WorldWideScience

Sample records for program etv joint

  1. ENVIRONMENTAL TECHNOLOGY VERIFICATION (ETV) PROGRAM: GREEN BUILDING TECHNOLOGIES

    Science.gov (United States)

    The U.S. Environmental Protection Agency (EPA) Environmental Technology Verification (ETV) Program evaluates the performance of innovative air, water, pollution prevention and monitoring technologies that have the potential to improve human health and the environment. This techno...

  2. ETV Program Report: Coatings for Wastewater Collection ...

    Science.gov (United States)

    The Standard Cement Materials, Inc. Standard Epoxy Coating 4553™ (SEC 4553) epoxy coating used for wastewater collection system rehabilitation was evaluated by EPA’s Environmental Technology Verification Program under laboratory conditions at the Center for Innovative Grouting Material and Technology (CIGMAT) Laboratory at the University of Houston. Testing was conducted over a period of six months to evaluate the coating’s (1) chemical resistance and (2) bonding strength for infrastructure applications. For chemical resistance, coated concrete and clay bricks with holidays (holes created in the coating) were used to evaluate the chemical resistance of the coating/substrate bond under a corrosive environment. Twenty coated concrete (dry and wet) and 20 coated clay brick (dry and wet) specimens were exposed to DI water and sulfuric acid solution (pH=1), and the specimens were visually inspected and weight changes measured. Evaluation of the coating-to-substrate bonding strength was determined using two modified ASTM test methods – one to determine bond strength of the coating with two specimens sandwiched together using the coating, and the second to determine the bond strength by applying a tensile load to the coating applied to specimens of each substrate. Forty-eight bonding tests were performed over the six month evaluation. The tests resulted in the following conclusions about Standard Cement’s SEC 4553 coating: • After the six-month chemi

  3. U.S. ENVIRONMENTAL PROTECTION AGENCY (EPA) ENVIRONMENTAL TECHNOLOGY VERIFICATION (ETV) PROGRAM: ARSENIC MONITORING TECHNOLOGIES

    Science.gov (United States)

    The U.S. Environmental Protection Agency Environmental Technology Verification (ETV) program evaluates the performance of innovative air, water, pollution prevention and monitoring technologies that have the potential to improve human health and the environment. This technology ...

  4. U.S. ENVIRONMENTAL PROTECTION AGENCY (EPA) ENVIRONMENTAL TECHNOLOGY VERIFICATION (ETV) PROGRAM: ARSENIC TREATMENT TECHNOLOGIES

    Science.gov (United States)

    The U.S. Environmental Protection Agency (EPA) Environmental Technology Verification (ETV) program evaluates the performance of innovative air, water, pollution prevention and monitoring technologies that have the potential to improve human health and the environment. This techn...

  5. Performance Testing of Homeland Security Technologies in U.S. EPA's Environmental Technology Verification (ETV) Program

    National Research Council Canada - National Science Library

    Kelly, Thomas J; Hofacre, Kent C; Derringer, Tricia L; Riggs, Karen B; Koglin, Eric N

    2004-01-01

    ... (reports and test plans available at www.epa.gov/etv). In the aftermath of the terrorist attacks of September 11, 2001, the ETV approach has also been employed in performance tests of technologies relevant to homeland security (HS...

  6. ETV - HOMELAND SECURITY EVALUATION OF CYANIDE DETECTORS

    Science.gov (United States)

    EPA's Environmental Technology Verification (ETV) Program was established in 1995 to objectively verify the performance of technologies that measure / monitor the quality of our environment, both for background or at suspected contamination site. The ETV program has established...

  7. Tantsufilm "Teine" ETV-s

    Index Scriptorium Estoniae

    2005-01-01

    Täna on ETV-s rahvusvahelises ühistöös valminud tantsufilm "Teine" ("Another") : režissöör Rene Vilbre : stsenaristid Rene Vilbre, Teet Kask, Helena Jonsdottir : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir : osatäitjad Mait Malmsten, Ruslan Stepanov. Filmi võtted toimusid Tartu vanglas

  8. Jointly Sponsored Research Program

    Energy Technology Data Exchange (ETDEWEB)

    Everett A. Sondreal; John G. Hendrikson; Thomas A. Erickson

    2009-03-31

    U.S. Department of Energy (DOE) Cooperative Agreement DE-FC26-98FT40321 funded through the Office of Fossil Energy and administered at the National Energy Technology Laboratory (NETL) supported the performance of a Jointly Sponsored Research Program (JSRP) at the Energy & Environmental Research Center (EERC) with a minimum 50% nonfederal cost share to assist industry in commercializing and effectively applying highly efficient, nonpolluting energy systems that meet the nation's requirements for clean fuels, chemicals, and electricity in the 21st century. The EERC in partnership with its nonfederal partners jointly performed 131 JSRP projects for which the total DOE cost share was $22,716,634 (38%) and the nonfederal share was $36,776,573 (62%). Summaries of these projects are presented in this report for six program areas: (1) resource characterization and waste management, (2) air quality assessment and control, (3) advanced power systems, (4) advanced fuel forms, (5) value-added coproducts, and (6) advanced materials. The work performed under this agreement addressed DOE goals for reductions in CO{sub 2} emissions through efficiency, capture, and sequestration; near-zero emissions from highly efficient coal-fired power plants; environmental control capabilities for SO{sub 2}, NO{sub x}, fine respirable particulate (PM{sub 2.5}), and mercury; alternative transportation fuels including liquid synfuels and hydrogen; and synergistic integration of fossil and renewable resources.

  9. ETV Program Report: Coatings for Wastewater Collection Systems - Standard Cement Materials, Epoxy Coating 4553

    Science.gov (United States)

    The Standard Cement Materials, Inc. Standard Epoxy Coating 4553™ (SEC 4553) epoxy coating used for wastewater collection system rehabilitation was evaluated by EPA’s Environmental Technology Verification Program under laboratory conditions at the Center for Innovative Grouting Ma...

  10. ETV VERTIFICATION REPORT AND VERIFICATION STATEMENT: COOPER POWER SYSTEMS ENVIROTEMP® FR3™ VEGETABLE OIL-BASED INSULATING DIELECTRIC FLUID

    Science.gov (United States)

    EPA's ETV Program, through the NRMRL has partnered with the California Department of Toxic Substances Control (DTSC) under an ETV Pilot Project to verify pollution prevention, recycling, and waste treatment technologies. This report and statement provides documentation of perfor...

  11. AN ENVIRONMENTAL TECHNOLOGY VERIFICATION (ETV) TESTING OF TWO HYDROGEN SULFIDE ANALYZERS: HORIBA INSTRUMENTS, INC., APSA-360 AND TELEDYNE-API MODEL 101E

    Science.gov (United States)

    The Environmental Technology Verification (ETV) Program, beginning as an initiative of the U.S. Environmental Protection Agency (EPA) in 1995, verifies the performance of commercially available, innovative technologies that can be used to measure environmental quality. The ETV p...

  12. enter endoscopic third ventriculostomy (ETV)

    African Journals Online (AJOL)

    hydrocephalus and how they explain the effectiveness of ETV in treating hydrocephalus ..... traditional indications, the proponents of the hydrodynamic theory suggest .... Adeloye A: The Rahima Dawood Memorial Guest Lecture. – December ...

  13. ETV teeb Tartu vanglas tantsufilmi

    Index Scriptorium Estoniae

    2005-01-01

    ETV-l valmib koos EFS-i ja Estinfilmiga kultuurikanali ARTE tellimusel tantsufilm "Teine" : režissöör Rene Vilbre : stsenarist Teet Kask : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir

  14. TEST DESIGN FOR ENVIRONMENTAL TECHNOLOGY VERIFICATION (ETV) OF ADD-ON NOX CONTROL UTILIZING OZONE INJECTION

    Science.gov (United States)

    The paper discusses the test design for environmental technology verification (ETV) of add-0n nitrogen oxides (NOx) control utilizing ozone injection. (NOTE: ETV is an EPA-established program to enhance domestic and international market acceptance of new or improved commercially...

  15. Joint shape segmentation with linear programming

    KAUST Repository

    Huang, Qixing; Koltun, Vladlen; Guibas, Leonidas

    2011-01-01

    program is solved via a linear programming relaxation, using a block coordinate descent procedure that makes the optimization feasible for large databases. We evaluate the presented approach on the Princeton segmentation benchmark and show that joint shape

  16. Joint shape segmentation with linear programming

    KAUST Repository

    Huang, Qixing

    2011-01-01

    We present an approach to segmenting shapes in a heterogenous shape database. Our approach segments the shapes jointly, utilizing features from multiple shapes to improve the segmentation of each. The approach is entirely unsupervised and is based on an integer quadratic programming formulation of the joint segmentation problem. The program optimizes over possible segmentations of individual shapes as well as over possible correspondences between segments from multiple shapes. The integer quadratic program is solved via a linear programming relaxation, using a block coordinate descent procedure that makes the optimization feasible for large databases. We evaluate the presented approach on the Princeton segmentation benchmark and show that joint shape segmentation significantly outperforms single-shape segmentation techniques. © 2011 ACM.

  17. ETV kutsub tantsule / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2003-01-01

    Tantsufilmide õhtu "Meeste mängud" ETVs. Lähemalt filmidest "The Car Man" (koreograaf Matthew Bourne, režissöör Ross MacGibbon), "Achilleuse tulek" ("Enter Achilleus" : koreograaf Lloyd Newson, režissöör Clara van Gool), "Ühevärvilised inimesed, elutud unistused" ("Dead Dreams of Monochrome Men" : koreograaf Lloyd Newson, režissöör David Hinton). Lisatud filmide kava

  18. Joint Chance-Constrained Dynamic Programming

    Science.gov (United States)

    Ono, Masahiro; Kuwata, Yoshiaki; Balaram, J. Bob

    2012-01-01

    This paper presents a novel dynamic programming algorithm with a joint chance constraint, which explicitly bounds the risk of failure in order to maintain the state within a specified feasible region. A joint chance constraint cannot be handled by existing constrained dynamic programming approaches since their application is limited to constraints in the same form as the cost function, that is, an expectation over a sum of one-stage costs. We overcome this challenge by reformulating the joint chance constraint into a constraint on an expectation over a sum of indicator functions, which can be incorporated into the cost function by dualizing the optimization problem. As a result, the primal variables can be optimized by a standard dynamic programming, while the dual variable is optimized by a root-finding algorithm that converges exponentially. Error bounds on the primal and dual objective values are rigorously derived. We demonstrate the algorithm on a path planning problem, as well as an optimal control problem for Mars entry, descent and landing. The simulations are conducted using a real terrain data of Mars, with four million discrete states at each time step.

  19. Joint Degree Program: the Perspective of Employers

    Directory of Open Access Journals (Sweden)

    Tatjana Bilevičienė

    2013-08-01

    Full Text Available Purpose — the purpose of this article is to extend discussion towards the need and importance of joint degree programs in modern universities, introducing the perspective of the employers toward this question. Design/methodology/approach — the research was conducted to analyze the demand of joint degree programs from the perspective of employers, identify weak and strong aspects, opinion and demand for graduates of such programs. To achieve this purpose, a combination of theoretical and empirical methods was chosen: document analysis (previous studies, statistics was conducted and an online qualitative survey was organized. Findings — The analysis of articles, studies and statistics points out the challenges and threats faced by universities nowadays, forcing higher education institutions to find new ways to raise the quality of studies and raise the interest of employers to choose graduates from MRU, as well as the satisfaction of employers with their choice of employees. Theoretical analysis pointed out these challenges and requirements for the modern employee, summarised the challenges in preparation of IT field specialists. The conducted research results showed that the diploma of joint degree programs would not be treated as an advantage of possible employee from the perspective of employers in case some important aspects will not be taken into consideration by program creators. On the other hand, undeniably there are strong sides, such as knowledge in the fields of foreign language, international experience, innovativeness and creativeness of employees that would be treated as an advantage in the process of selection for positions of any technical support related positions. Research limitations/implications — employers, whose business activities are closely related to information technology, have been invited as experts. In addition, these experts have a good understanding of the specifics of joint degree programs. The received

  20. Designing and Managing Successful International Joint Development Programs

    Science.gov (United States)

    2016-04-30

    joint development programs are important because of their potential to reduce costs and increase partnership benefits such as interoperability, economies ...have actualized by discussing what characteristics research has shown as crucial to international joint development program outcomes. The study team... characteristics of international joint development programs that result in positive or negative cost, scheduling, and end-product outcomes, such as a final

  1. ANIMAL WASTE IMPACT ON SOURCE WATERSAIDED BY EPA/NSF ENVIRONMENTAL TECHNOLOGY VERIFICATION (ETV) SOURCE WATER PROTECTION PILOT

    Science.gov (United States)

    The Environmental Technology Verification Program (ETV) was established in 1995 by the U.S. Environmental Protection Agency to encourage the development and commercialization of new environmental technologies through third part testing and reporting of performance data. By ensur...

  2. Comunidad del conocimiento Ecosalud Etv

    Directory of Open Access Journals (Sweden)

    Laura Magaña Valladares

    2013-01-01

    Full Text Available El Proyecto Liderazgo en Ecosalud para las Enfermedades Transmitidas por Vectores (ETV en América Latina y el Caribe colocó entre los principales objetivos de trabajo la conformación de una comunidad del conocimiento que garantizara la sostenibilidad de la estrategia de capacitación. Este artículo es el resultado de una investigación documental centrada en la construcción de una comunidad del conocimiento desde el Portal de la iniciativa, aprovechando las bondades del trabajo colaborativo que brinda la perspectiva de la web 2.0 y colocando a las tecnologías de la información y las comunicaciones como un agente clave al servicio de la salud pública en la región.

  3. Jointly Sponsored Research Program Energy Related Research

    Energy Technology Data Exchange (ETDEWEB)

    Western Research Institute

    2009-03-31

    Cooperative Agreement, DE-FC26-98FT40323, Jointly Sponsored Research (JSR) Program at Western Research Institute (WRI) began in 1998. Over the course of the Program, a total of seventy-seven tasks were proposed utilizing a total of $23,202,579 in USDOE funds. Against this funding, cosponsors committed $26,557,649 in private funds to produce a program valued at $49,760,228. The goal of the Jointly Sponsored Research Program was to develop or assist in the development of innovative technology solutions that will: (1) Increase the production of United States energy resources - coal, natural gas, oil, and renewable energy resources; (2) Enhance the competitiveness of United States energy technologies in international markets and assist in technology transfer; (3) Reduce the nation's dependence on foreign energy supplies and strengthen both the United States and regional economies; and (4) Minimize environmental impacts of energy production and utilization. Under the JSR Program, energy-related tasks emphasized enhanced oil recovery, heavy oil upgrading and characterization, coal beneficiation and upgrading, coal combustion systems development including oxy-combustion, emissions monitoring and abatement, coal gasification technologies including gas clean-up and conditioning, hydrogen and liquid fuels production, coal-bed methane recovery, and the development of technologies for the utilization of renewable energy resources. Environmental-related activities emphasized cleaning contaminated soils and waters, processing of oily wastes, mitigating acid mine drainage, and demonstrating uses for solid waste from clean coal technologies, and other advanced coal-based systems. Technology enhancement activities included resource characterization studies, development of improved methods, monitors and sensors. In general the goals of the tasks proposed were to enhance competitiveness of U.S. technology, increase production of domestic resources, and reduce environmental

  4. Minister proposes re-introducing ETV commercials / Kairi Kurm

    Index Scriptorium Estoniae

    Kurm, Kairi

    2005-01-01

    Kultuuriminister Raivo Palmaru tegi ettepaneku hakata ETV-s taas reklaami näitama, millest saadud tuludega suurendada telekanali eelarvet. Kanal 2 ja TV3 juhtide arvates mõjutaks see meediaturu stabiilsust ning oleks ebaaus konkurents

  5. DOE-EERC jointly sponsored research program

    Energy Technology Data Exchange (ETDEWEB)

    Hendrikson, J.G.; Sondreal, E.A.

    1999-09-01

    U.S. Department of Energy (DOE) Cooperative Agreement DE-FC21-93MC30098 funded through the Office of Fossil Energy and administered at the Federal Energy Technology Center (FETC) supported the performance of a Jointly Sponsored Research Program (JSRP) at the Energy and Environmental Research Center (EERC) with a minimum 50% nonfederal cost share to assist industry in commercializing and effectively applying efficient, nonpolluting energy technologies that can compete effectively in meeting market demands for clean fuels, chemical feedstocks, and electricity in the 21st century. The objective of the JSRP was to advance the deployment of advanced technologies for improving energy efficiency and environmental performance through jointly sponsored research on topics that would not be adequately addressed by the private sector alone. Examples of such topics include the barriers to hot-gas cleaning impeding the deployment of high-efficiency power systems and the search for practical means for sequestering CO{sub 2} generated by fossil fuel combustion. The selection of particular research projects was guided by a combination of DOE priorities and market needs, as provided by the requirement for joint venture funding approved both by DOE and the private sector sponsor. The research addressed many different energy resource and related environmental problems, with emphasis directed toward the EERC's historic lead mission in low-rank coals (LRCs), which represent approximately half of the U.S. coal resources in the conterminous states, much larger potential resources in Alaska, and a major part of the energy base in the former U.S.S.R., East Central Europe, and the Pacific Rim. The Base and JSRP agreements were tailored to the growing awareness of critical environmental issues, including water supply and quality, air toxics (e.g., mercury), fine respirable particulate matter (PM{sub 2.5}), and the goal of zero net CO{sub 2} emissions.

  6. Analysis list: Etv2 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Etv2 Pluripotent stem cell + mm9 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/Et...v2.1.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/Etv2.5.tsv http://dbarchive.bioscienced...bc.jp/kyushu-u/mm9/target/Etv2.10.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/Etv2.Pluripotent_s

  7. Testing program for burning plasma experiment vacuum vessel bolted joint

    International Nuclear Information System (INIS)

    Hsueh, P.K.; Khan, M.Z.; Swanson, J.; Feng, T.; Dinkevich, S.; Warren, J.

    1992-01-01

    As presently designed, the Burning Plasma Experiment vacuum vessel will be segmentally fabricated and assembled by bolted joints in the field. Due to geometry constraints, most of the bolted joints have significant eccentricity which causes the joint behavior to be sensitive to joint clamping forces. Experience indicates that as a result of this eccentricity, the joint will tend to open at the side closest to the applied load with the extent of the opening being dependent on the initial preload. In this paper analytical models coupled with a confirmatory testing program are developed to investigate and predict the non-linear behavior of the vacuum vessel bolted joint

  8. Program Management Challenges in a Joint Service Environment

    National Research Council Canada - National Science Library

    Taneyhill, Dorothy E

    2007-01-01

    ... or modifications of the same design. The Interim Defense Acquisition Guidebook defines a Joint Program Management Office as any defense acquisition system, subsystem, component, or technology program that involves formal management...

  9. Failure of ETV in patients with the highest ETV success scores.

    Science.gov (United States)

    Gianaris, Thomas J; Nazar, Ryan; Middlebrook, Emily; Gonda, David D; Jea, Andrew; Fulkerson, Daniel H

    2017-09-01

    OBJECTIVE Endoscopic third ventriculostomy (ETV) is a surgical alternative to placing a CSF shunt in certain patients with hydrocephalus. The ETV Success Score (ETVSS) is a reliable, simple method to estimate the success of the procedure by 6 months of postoperative follow-up. The highest score is 90, estimating a 90% chance of the ETV effectively treating hydrocephalus without requiring a shunt. Treatment with ETV fails in certain patients, despite their being the theoretically best candidates for the procedure. In this study the authors attempted to identify factors that further predicted success in patients with the highest ETVSSs. METHODS A retrospective review was performed of all patients treated with ETV at 3 institutions. Demographic, radiological, and clinical data were recorded. All patients by definition were older than 1 year, had obstructive hydrocephalus, and did not have a prior shunt. Failure of ETV was defined as the need for a shunt by 1 year. The ETV was considered a success if the patient did not require another surgery (either shunt placement or a repeat endoscopic procedure) by 1 year. A statistical analysis was performed to identify factors associated with success or failure. RESULTS Fifty-nine patients met the entry criteria for the study. Eleven patients (18.6%) required further surgery by 1 year. All of these patients received a shunt. The presenting symptom of lethargy statistically correlated with success (p = 0.0126, odds ratio [OR] = 0.072). The preoperative radiological finding of transependymal flow (p = 0.0375, OR 0.158) correlated with success. A postoperative larger maximum width of the third ventricle correlated with failure (p = 0.0265). CONCLUSIONS The preoperative findings of lethargy and transependymal flow statistically correlated with success. This suggests that the best candidates for ETV are those with a relatively acute elevation of intracranial pressure. Cases without these findings may represent the failures in this

  10. ETV katuse all keedeti salaseepi / Tiina Jõgeda

    Index Scriptorium Estoniae

    Jõgeda, Tiina, 1962-

    2011-01-01

    Rahvusringhäälingu (ERR) tootmisteenistuse juhataja Janno-Hans Arro, kes seoses pettustega vallandati augustis ERR-ist, valmistas mitu aastat ette suurejoonelist kodumaist teleseriaali. Seriaali filmiti sel suvel Madeiral. Põhjendustest, miks ETV seda ära osta ei taha

  11. ETVs näeb uusi dokfilme

    Index Scriptorium Estoniae

    2006-01-01

    ETVs täna kolm noore autori 2005.a. valminud dokumentaalfilmi : Kullar Viimse "Jumalaga", Kristin Raubi "O.M.V.K." ja Riin Kranna ja shveitslase Enrico Pizzolato "Vaimu võsuke". Viimase filmi meeskond koosneb India filmitudengitest, tegevus toimub Indias

  12. Austraallased huvituvad ETV toodangust / Karin Leemet

    Index Scriptorium Estoniae

    Leemet, Karin

    2000-01-01

    ETV saadet "Simson Seakülast" näidatakse peagi Austraalia telekanalil The Special Broadcasting Service. 1995. a. valminud kunstisaade on eesti skulptorist Aivar Simsonist, saate autorid Mariina Mälk, Peeter Brambat, operaator Peep Laansalu. Mari Sobolev A. Simsoni töödest

  13. Novel RNA hybridization method for the in situ detection of ETV1, ETV4, and ETV5 gene fusions in prostate cancer.

    Science.gov (United States)

    Kunju, Lakshmi P; Carskadon, Shannon; Siddiqui, Javed; Tomlins, Scott A; Chinnaiyan, Arul M; Palanisamy, Nallasivam

    2014-09-01

    The genetic basis of 50% to 60% of prostate cancer (PCa) is attributable to rearrangements in E26 transformation-specific (ETS) (ERG, ETV1, ETV4, and ETV5), BRAF, and RAF1 genes and overexpression of SPINK1. The development and validation of reliable detection methods are warranted to classify various molecular subtypes of PCa for diagnostic and prognostic purposes. ETS gene rearrangements are typically detected by fluorescence in situ hybridization and reverse-transcription polymerase chain reaction methods. Recently, monoclonal antibodies against ERG have been developed that detect the truncated ERG protein in immunohistochemical assays where staining levels are strongly correlated with ERG rearrangement status by fluorescence in situ hybridization. However, specific antibodies for ETV1, ETV4, and ETV5 are unavailable, challenging their clinical use. We developed a novel RNA in situ hybridization-based assay for the in situ detection of ETV1, ETV4, and ETV5 in formalin-fixed paraffin-embedded tissues from prostate needle biopsies, prostatectomy, and metastatic PCa specimens using RNA probes. Further, with combined RNA in situ hybridization and immunohistochemistry we identified a rare subset of PCa with dual ETS gene rearrangements in collisions of independent tumor foci. The high specificity and sensitivity of RNA in situ hybridization provides an alternate method enabling bright-field in situ detection of ETS gene aberrations in routine clinically available PCa specimens.

  14. Analysis list: Etv6 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Etv6 Blood + mm9 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/Etv6.1.tsv h...ttp://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/Etv6.5.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/Et...v6.10.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/Etv6.Blood.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/Blood.gml ...

  15. ETV ekraanigraafika on Euroopa parimate seas / René Vilbre

    Index Scriptorium Estoniae

    Vilbre, René, 1970-

    2011-01-01

    Euroopa avalik-õiguslikle telejaamade konkurentsis valiti ETV ekraanigraafika viie parima hulka. Finaali pääses ETV kahes kategoorias - "Best design package" ja "Best use of audio". Intervjuu vaheklippide autori René Vilbrega. Võttemeeskonda kuulusid veel toimetaja Anu Välba, operaatorid Kristjan-Jaak Nuudi ja Ergo Treier

  16. A Study of Joint Cost Inclusion in Linear Programming Optimization

    Directory of Open Access Journals (Sweden)

    P. Armaos

    2013-08-01

    Full Text Available The concept of Structural Optimization has been a topic or research over the past century. Linear Programming Optimization has proved being the most reliable method of structural optimization. Global advances in linear programming optimization have been recently powered by University of Sheffield researchers, to include joint cost, self-weight and buckling considerations. A joint cost inclusion scopes to reduce the number of joints existing in an optimized structural solution, transforming it to a practically viable solution. The topic of the current paper is to investigate the effects of joint cost inclusion, as this is currently implemented in the optimization code. An extended literature review on this subject was conducted prior to familiarization with small scale optimization software. Using IntelliFORM software, a structured series of problems were set and analyzed. The joint cost tests examined benchmark problems and their consequent changes in the member topology, as the design domain was expanding. The findings of the analyses were remarkable and are being commented further on. The distinct topologies of solutions created by optimization processes are also recognized. Finally an alternative strategy of penalizing joints is presented.

  17. Quality Assurance in Environmental Technology Verification (ETV): Analysis and Impact on the EU ETV Pilot Programme Performance

    Science.gov (United States)

    Molenda, Michał; Ratman-Kłosińska, Izabela

    2018-03-01

    Many innovative environmental technologies never reach the market because they are new and cannot demonstrate a successful track record of previous applications. This fact is a serious obstacle on their way to the market. Lack of credible data on the performance of a technology causes mistrust of investors in innovations, especially from public sector, who seek effective solutions however without compromising the technical and financial risks associated with their implementation. Environmental technology verification (ETV) offers a credible, robust and transparent process that results in a third party confirmation of the claims made by the providers about the performance of the novel environmental technologies. Verifications of performance are supported by high quality, independent test data. In that way ETV as a tool helps establish vendor credibility and buyer confidence. Several countries across the world have implemented ETV in the form of national or regional programmes. ETV in the European Union was implemented as a voluntary scheme if a form of a pilot programme. The European Commission launched the Environmental Technology Pilot Programme of the European Union (EU ETV) in 2011. The paper describes the European model of ETV set up and put to operation under the Pilot Programme of Environmental Technologies Verification of the European Union. The goal, objectives, technological scope, involved entities are presented. An attempt has been made to summarise the results of the EU ETV scheme performance available for the period of 2012 when the programme has become fully operational until the first half of 2016. The study was aimed at analysing the overall organisation and efficiency of the EU ETV Pilot Programme. The study was based on the analysis of the documents the operation of the EU ETV system. For this purpose, a relevant statistical analysis of the data on the performance of the EU ETV system provided by the European Commission was carried out.

  18. Government-sponsored microfinance program: Joint liability vs. individual liability

    Directory of Open Access Journals (Sweden)

    Arghya Kusum Mukherjee

    2014-12-01

    Full Text Available Swarnajayanti Gram Swarozgar Yojana (SGSY is a government-sponsored microfinance program. The scheme is based on four features: group lending with joint liability, progressive lending, back-ended subsidy, and social capital. We propose a new model of SGSY having these features: group lending with individual liability, progressive lending, back-ended subsidy, and social capital. “Joint liability” clause of the existing model is replaced with individual liability in the new model. The paper shows that problem of adverse selection is removed in both models, i.e. in “SGSY with group lending and joint liability” and “SGSY with group lending and individual liability.” The problem of “moral hazard” is more severe in the existing model of SGSY compared with the proposed model of SGSY. Borrowers are also benefitted from participation in the proposed scheme of SGSY than that in the existing model of SGSY.

  19. ETV uus seriaal "Vistrik" kavatseb nime muuta / Anne Vetik

    Index Scriptorium Estoniae

    Vetik, Anne

    2006-01-01

    Toimuvad ETV uue krimisarja "Vistrik" võtted, stsenarist Mihkel Ulman, režissöör Ain Prosa, produtsent Raivo Suviste, kesksetes rollides Marko Matvere, Jaan Rekkor, Elisabet Tamm, tootjaks OÜ Balti Video

  20. Optimal timing of joint replacement using mathematical programming and stochastic programming models.

    Science.gov (United States)

    Keren, Baruch; Pliskin, Joseph S

    2011-12-01

    The optimal timing for performing radical medical procedures as joint (e.g., hip) replacement must be seriously considered. In this paper we show that under deterministic assumptions the optimal timing for joint replacement is a solution of a mathematical programming problem, and under stochastic assumptions the optimal timing can be formulated as a stochastic programming problem. We formulate deterministic and stochastic models that can serve as decision support tools. The results show that the benefit from joint replacement surgery is heavily dependent on timing. Moreover, for a special case where the patient's remaining life is normally distributed along with a normally distributed survival of the new joint, the expected benefit function from surgery is completely solved. This enables practitioners to draw the expected benefit graph, to find the optimal timing, to evaluate the benefit for each patient, to set priorities among patients and to decide if joint replacement should be performed and when.

  1. F-35 Joint Strike Fighter: Preliminary Observations on Program Progress

    Science.gov (United States)

    2016-03-23

    current fighter aircraft. The cost of extending the lives of current fighter aircraft and acquiring other major weapon systems, while continuing to... Norway . Ongoing Manufacturing and Reliability Progress Continue Page 12 GAO-16-489T rework, and repair costs have remained steady over...Program Progress Why GAO Did This Study With estimated acquisition costs of nearly $400 billion, the F-35 Joint Strike Fighter—also known as the

  2. 76 FR 2147 - UAW-Chrysler National Training Center Technology Training Joint Programs Staff, Detroit, MI; UAW...

    Science.gov (United States)

    2011-01-12

    ...-Chrysler National Training Center Technology Training Joint Programs Staff, Detroit, MI; UAW-Chrysler Technical Training Center Technology Training Joint Programs Staff, Warren, MI; Notice of Revised... investigation, the Department confirmed that the proportion of Technology Training Joint Programs Staff...

  3. Characterization of leukemias with ETV6-ABL1 fusion

    Science.gov (United States)

    Zaliova, Marketa; Moorman, Anthony V.; Cazzaniga, Giovanni; Stanulla, Martin; Harvey, Richard C.; Roberts, Kathryn G.; Heatley, Sue L.; Loh, Mignon L.; Konopleva, Marina; Chen, I-Ming; Zimmermannova, Olga; Schwab, Claire; Smith, Owen; Mozziconacci, Marie-Joelle; Chabannon, Christian; Kim, Myungshin; Frederik Falkenburg, J. H.; Norton, Alice; Marshall, Karen; Haas, Oskar A.; Starkova, Julia; Stuchly, Jan; Hunger, Stephen P.; White, Deborah; Mullighan, Charles G.; Willman, Cheryl L.; Stary, Jan; Trka, Jan; Zuna, Jan

    2016-01-01

    To characterize the incidence, clinical features and genetics of ETV6-ABL1 leukemias, representing targetable kinase-activating lesions, we analyzed 44 new and published cases of ETV6-ABL1-positive hematologic malignancies [22 cases of acute lymphoblastic leukemia (13 children, 9 adults) and 22 myeloid malignancies (18 myeloproliferative neoplasms, 4 acute myeloid leukemias)]. The presence of the ETV6-ABL1 fusion was ascertained by cytogenetics, fluorescence in-situ hybridization, reverse transcriptase-polymerase chain reaction and RNA sequencing. Genomic and gene expression profiling was performed by single nucleotide polymorphism and expression arrays. Systematic screening of more than 4,500 cases revealed that in acute lymphoblastic leukemia ETV6-ABL1 is rare in childhood (0.17% cases) and slightly more common in adults (0.38%). There is no systematic screening of myeloproliferative neoplasms; however, the number of ETV6-ABL1-positive cases and the relative incidence of acute lymphoblastic leukemia and myeloproliferative neoplasms suggest that in adulthood ETV6-ABL1 is more common in BCR-ABL1-negative chronic myeloid leukemia-like myeloproliferations than in acute lymphoblastic leukemia. The genomic profile of ETV6-ABL1 acute lymphoblastic leukemia resembled that of BCR-ABL1 and BCR-ABL1-like cases with 80% of patients having concurrent CDKN2A/B and IKZF1 deletions. In the gene expression profiling all the ETV6-ABL1-positive samples clustered in close vicinity to BCR-ABL1 cases. All but one of the cases of ETV6-ABL1 acute lymphoblastic leukemia were classified as BCR-ABL1-like by a standardized assay. Over 60% of patients died, irrespectively of the disease or age subgroup examined. In conclusion, ETV6-ABL1 fusion occurs in both lymphoid and myeloid leukemias; the genomic profile and clinical behavior resemble BCR-ABL1-positive malignancies, including the unfavorable prognosis, particularly of acute leukemias. The poor outcome suggests that treatment with

  4. File list: Oth.PSC.10.Etv2.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.PSC.10.Etv2.AllCell mm9 TFs and others Etv2 Pluripotent stem cell SRX652259,SRX...652260 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Oth.PSC.10.Etv2.AllCell.bed ...

  5. FY 2002 End of Year Report (Joint Advanced Warfighting Program)

    National Research Council Canada - National Science Library

    Gold, Theodore

    2003-01-01

    ...) I Experiment and joint urban operations. However, other JAWP activities are described, for example, metrics for transformation, continuous joint experimentation, commercial-off-the-shelf (COTS...

  6. DOE/PNC joint program on transportation technology

    International Nuclear Information System (INIS)

    Kubo, M.; Kajitani, M.; Seya, M.; Yoshimura, H.R.; Moya, J.L.; May, R.A.; Huerta, M.; Stenberg, D.R.

    1986-01-01

    This paper summarizes the work performed in a cooperative program on transportation technology between the Department of Energy (DOE) and the Power Reactor and Nuclear Fuel Development Corporation (PNC) of Japan. This work was performed at Sandia National Laboratories (SNL) in Albuquerque, New Mexico. The joint program emphasized the safety analysis for truck transportation of special nuclear materials (SNM) in Japan. Tasks included structural analyses and testing, thermal testing, leak rate studies and tests, and transportation risk assessments. The purpose of this paper is to present the results of full-scale structural and thermal tests conducted on a PNC development SNM transport system. Correlation of full-scale impact test results with structural analysis and scale model testing will also be reviewed

  7. The obesity-associated transcription factor ETV5 modulates circulating glucocorticoids

    Science.gov (United States)

    Gutierrez-Aguilar, Ruth; Thompson, Abigail; Marchand, Nathalie; Dumont, Patrick; Woods, Stephen C.; de Launoit, Yvan; Seeley, Randy J.; Ulrich-Lai, Yvonne M.

    2015-01-01

    The transcription factor E-twenty-six version 5 (ETV5) has been linked with obesity in genome-wide association studies. Moreover, ETV5-deficient mice (knockout; KO) have reduced body weight, lower fat mass, and are resistant to diet-induced obesity, directly linking ETV5 to the regulation of energy balance and metabolism. ETV5 is expressed in hypothalamic brain regions that regulate both metabolism and HPA axis activity, suggesting that ETV5 may also modulate HPA axis function. In order to test this possibility, plasma corticosterone levels were measured in ETV5 KO and wildtype (WT) mice before (pre-stress) and after (post-stress) a mild stressor (intraperitoneal injection). ETV5 deficiency increased both pre- and post-stress plasma corticosterone, suggesting that loss of ETV5 elevated glucocorticoid tone. Consistent with this idea, ETV5 KO mice have reduced thymus weight, suggestive of increased glucocorticoid-induced thymic involution. ETV5 deficiency also decreased the mRNA expression of glucocorticoid receptor (GR), mineralocorticoid receptor (MR), and vasopressin receptor 1A in the hypothalamus, without altering vasopressin, corticotropin-releasing hormone, or oxytocin mRNA expression. In order to test whether reduced MR and GR expression affected glucocorticoid negative feedback, a dexamethasone suppression test was performed. Dexamethasone reduced plasma corticosterone in both ETV5 KO and WT mice, suggesting that glucocorticoid negative feedback was unaltered by ETV5 deficiency. In summary, these data suggest that the obesity-associated transcription factor ETV5 normally acts to diminish circulating glucocorticoids. This might occur directly via ETV5 actions on HPA-regulatory brain circuitry, and/or indirectly via ETV5-induced alterations in metabolic factors that then influence the HPA axis. PMID:25813907

  8. Clonal origins of ETV6-RUNX1+ acute lymphoblastic leukemia

    DEFF Research Database (Denmark)

    Alpar, D.; Wren, D.; Ermini, Luca

    2015-01-01

    Studies on twins with concordant acute lymphoblastic leukemia (ALL) have revealed that ETV6-RUNX1 gene fusion is a common, prenatal genetic event with other driver aberrations occurring subclonally and probably postnatally. The fetal cell type that is transformed by ETV6-RUNX1 is not identified...... by such studies or by the analysis of early B-cell lineage phenotype of derived progeny. Ongoing, clonal immunoglobulin (IG) and cross-lineage T-cell receptor (TCR) gene rearrangements are features of B-cell precursor leukemia and commence at the pro-B-cell stage of normal B-cell lineage development. We reasoned...

  9. ETV noortekoor võitis Šveitsi koorifestivali peapreemia

    Index Scriptorium Estoniae

    2009-01-01

    ETV noortekoor Külli Kiiveti juhatusel pälvis 14.-19. aprillini Šveitsis toimunud 45. rahvusvahelisel koorifestivalil "Montreux Choral Festival 2009" nii žürii peapreemia kui ka parima kava ja interpretatsiooni ning kohustusliku laulu preemia

  10. Current status of Joint FAA/NASA Runway Friction Program

    Science.gov (United States)

    Yager, Thomas J.; Vogler, William A.

    1989-01-01

    Tests with specially instrumented NASA B-737 and FAA B-727 aircraft together with several different ground friction measuring devices have been conducted for a variety of runway surface types and wetness conditions. This effort is part of the Joint FAA/NASA Aircraft Ground Vehicle Runway Friction Program aimed at obaining a better understanding of aircraft ground handling performance under adverse weather conditions and defining relationships between aircraft and ground vehicle tire friction measurements. Aircraft braking performance on dry, wet, snow-, and ice-covered runway conditions is discussed together with ground vehicle friction data obtained under similar runway conditions. For the wet, compacted snow- and ice-covered runway conditions, the relationship between ground vehicles and aircraft friction data is identified. The influence of major test parameters on friction measurements such as speed, test tire characteristics, and surface contaminant type are discussed. The test results indicate that use of properly maintained and calibrated ground vehicles for monitoring runway friction conditions should be encouraged particularly under adverse weather conditions. The current status of the runway friction program is summarized and future test plans are identified.

  11. 76 FR 35474 - UAW-Chrysler Technical Training Center, Technology Training Joint Programs Staff, Including On...

    Science.gov (United States)

    2011-06-17

    ...-Chrysler Technical Training Center, Technology Training Joint Programs Staff, Including On-Site Leased Workers From Cranks, O/E Learning, DBSI, IDEA, and Tonic/MVP, Detroit, MI; UAW-Chrysler Technical Training... workers and former workers of UAW-Chrysler Technical Training Center, Technology Training Joint Programs...

  12. Semiconductor laser joint study program with Rome Laboratory

    Science.gov (United States)

    Schaff, William J.; Okeefe, Sean S.; Eastman, Lester F.

    1994-09-01

    A program to jointly study vertical-cavity surface emitting lasers (VCSEL) for high speed vertical optical interconnects (VOI) has been conducted under an ES&E between Rome Laboratory and Cornell University. Lasers were designed, grown, and fabricated at Cornell University. A VCSEL measurement laboratory has been designed, built, and utilized at Rome Laboratory. High quality VCSEL material was grown and characterized by fabricating conventional lateral cavity lasers that emitted at the design wavelength of 1.04 microns. The VCSEL's emit at 1.06 microns. Threshold currents of 16 mA at 4.8 volts were obtained for 30 microns diameter devices. Output powers of 5 mW were measured. This is 500 times higher power than from the light emitting diodes employed previously for vertical optical interconnects. A new form of compositional grading using a cosinusoidal function has been developed and is very successful for reducing diode series resistance for high speed interconnection applications. A flip-chip diamond package compatible with high speed operation of 16 VCSEL elements has been designed and characterized. A flip-chip device binding effort at Rome Laboratory was also designed and initiated. This report presents details of the one-year effort, including process recipes and results.

  13. The Cost of Commonality: Assessing Value in Joint Programs

    Science.gov (United States)

    2015-12-01

    though product differentiation. This can manifest as a real or perceived value disparity. Thus, substantial coordination among system stakeholders is... satisfaction . Ultimately, incorporation of the Joint Value Model can contribute to more cost-effective solutions and greater value in joint capability...

  14. Elina Hokkaneni ootab ees ETV "Laulukarusselli" finaal / Ülle Lätte

    Index Scriptorium Estoniae

    Lätte, Ülle, 1955-

    2008-01-01

    ETVs 22. septembril laste lauluvõistlusel "Laulukarussell 2008" esinenud Jõgevamaa lauljate seast pääses finaalsaatesse Helina Hokkanen Põltsamaalt (juhendajaks Tiia Kaeramaa), saate lindistusest

  15. Long range plan for flexible joint development program

    International Nuclear Information System (INIS)

    Objective is to develop bellows expansion joints into CDS and subsequent LMFBR and liquid metal applications. An assessment was performed on the use of Incoloy 800H and Inconel 718 as bellows materials

  16. Joint Solutions to Substance Abuse: Public Sector Employee Assistance Programs.

    Science.gov (United States)

    State and Local Government Labor-Management Committee, Washington, DC.

    This short booklet is a joint expression by public sector labor and management that recognizes that neither side has all the answers to the problems of employee substance abuse and that both share a common concern for a successful outcome. The booklet summarizes the dimension of substance abuse in today's workplace; and it tries to encourage…

  17. Characterization of a newly identified ETV6-NTRK3 fusion transcript in acute myeloid leukemia

    Directory of Open Access Journals (Sweden)

    Erdel Martin

    2011-03-01

    Full Text Available Abstract Background Characterization of novel fusion genes in acute leukemia is important for gaining information about leukemia genesis. We describe the characterization of a new ETV6 fusion gene in acute myeloid leukemia (AML FAB M0 as a result of an uncommon translocation involving chromosomes 12 and 15. Methods The ETV6 locus at 12p13 was shown to be translocated and to constitute the 5' end of the fusion product by ETV6 break apart fluorescence in situ hybridisation (FISH. To identify a fusion partner 3' rapid amplification of cDNA-ends with polymerase chain reaction (RACE PCR was performed followed by cloning and sequencing. Results The NTRK3 gene on chromosome 15 was found to constitute the 3' end of the fusion gene and the underlying ETV6-NTRK3 rearrangement was verified by reverse transcriptase PCR. No RNA of the reciprocal NTRK3-ETV6 fusion gene could be detected. Conclusion We have characterized a novel ETV6-NTRK3 fusion transcript which has not been previously described in AML FAB M0 by FISH and RACE PCR. ETV6-NTRK3 rearrangements have been described in secretory breast carcinoma and congenital fibrosarcoma.

  18. 24 CFR 570.411 - Joint Community Development Program.

    Science.gov (United States)

    2010-04-01

    ... designated to work on the program, including subcontractors and consultants firmly committed to work on the... activities in a timely fashion, including satisfactory performance in carrying out any previous HUD-assisted...

  19. Teaching Joint-Level Robot Programming with a New Robotics Software Tool

    Directory of Open Access Journals (Sweden)

    Fernando Gonzalez

    2017-12-01

    Full Text Available With the rising popularity of robotics in our modern world there is an increase in the number of engineering programs that offer the basic Introduction to Robotics course. This common introductory robotics course generally covers the fundamental theory of robotics including robot kinematics, dynamics, differential movements, trajectory planning and basic computer vision algorithms commonly used in the field of robotics. Joint programming, the task of writing a program that directly controls the robot’s joint motors, is an activity that involves robot kinematics, dynamics, and trajectory planning. In this paper, we introduce a new educational robotics tool developed for teaching joint programming. The tool allows the student to write a program in a modified C language that controls the movement of the arm by controlling the velocity of each joint motor. This is a very important activity in the robotics course and leads the student to gain knowledge of how to build a robotic arm controller. Sample assignments are presented for different levels of difficulty.

  20. Jointly Sponsored Research Program on Energy Related Research

    Energy Technology Data Exchange (ETDEWEB)

    No, author

    2013-12-31

    Cooperative Agreements, DE-FC26-08NT43293, DOE-WRI Cooperative Research and Development Program for Fossil Energy-Related Resources began in June 2009. The goal of the Program was to develop, commercialize, and deploy technologies of value to the nation’s fossil and renewable energy industries. To ensure relevancy and early commercialization, the involvement of an industrial partner was encouraged. In that regard, the Program stipulated that a minimum of 20% cost share be achieved in a fiscal year. This allowed WRI to carry a diverse portfolio of technologies and projects at various development technology readiness levels. Depending upon the maturity of the research concept and technology, cost share for a given task ranged from none to as high as 67% (two-thirds). Over the course of the Program, a total of twenty six tasks were proposed for DOE approval. Over the period of performance of the Cooperative agreement, WRI has put in place projects utilizing a total of $7,089,581 in USDOE funds. Against this funding, cosponsors have committed $7,398,476 in private funds to produce a program valued at $14,488,057. Tables 1 and 2 presented at the end of this section is a compilation of the funding for all the tasks conducted under the program. The goal of the Cooperative Research and Development Program for Fossil Energy-Related Resources was to through collaborative research with the industry, develop or assist in the development of innovative technology solutions that will: • Increase the production of United States energy resources – coal, natural gas, oil, and renewable energy resources; • Enhance the competitiveness of United States energy technologies in international markets and assist in technology transfer; • Reduce the nation's dependence on foreign energy supplies and strengthen both the United States and regional economies; and • Minimize environmental impacts of energy production and utilization. Success of the Program can be measured by

  1. Joint Logistics Commanders Guide for the Management of Multinational Program,

    Science.gov (United States)

    1981-07-01

    purchase of the A-300 Airbus and the 1977 record-breaking export performance of the French and UK aerospace industries of around $5 billion and $2 billion...DIS. They are the Defense Industrial Security Clearance Office ( DISCO ), the Defense Industrial Security Institute (DISI), and the Office of Industrial...Security International (ISI). Defense Industrial Security Clearance Office ( DISCO ) The Defense Industrial Security Program (DISP) establishes pro

  2. Joint program for the improvement of bimetallic weld inspection

    International Nuclear Information System (INIS)

    Serre, M.; Rattoni, B.; Coquillay; Samman; Billet; Bodson; Olivera

    1985-02-01

    The aim of this program is to improve the in-service monitoring of austenitic and bimetallic welds in PWR Main Coolant Systems. This paper presents the work performed on the bimetallic weld connecting the safe end to the reactor vessel nozzle: suitability of ultrasonic testing for determining the size and location of defects, automation and calibration, gamma-ray examination in three different planes

  3. Clinical and pathogenic features of ETV6-related thrombocytopenia with predisposition to acute lymphoblastic leukemia

    Science.gov (United States)

    Melazzini, Federica; Palombo, Flavia; Balduini, Alessandra; De Rocco, Daniela; Marconi, Caterina; Noris, Patrizia; Gnan, Chiara; Pippucci, Tommaso; Bozzi, Valeria; Faleschini, Michela; Barozzi, Serena; Doubek, Michael; Di Buduo, Christian A.; Kozubik, Katerina Stano; Radova, Lenka; Loffredo, Giuseppe; Pospisilova, Sarka; Alfano, Caterina; Seri, Marco; Balduini, Carlo L.; Pecci, Alessandro; Savoia, Anna

    2016-01-01

    ETV6-related thrombocytopenia is an autosomal dominant thrombocytopenia that has been recently identified in a few families and has been suspected to predispose to hematologic malignancies. To gain further information on this disorder, we searched for ETV6 mutations in the 130 families with inherited thrombocytopenia of unknown origin from our cohort of 274 consecutive pedigrees with familial thrombocytopenia. We identified 20 patients with ETV6-related thrombocytopenia from seven pedigrees. They have five different ETV6 variants, including three novel mutations affecting the highly conserved E26 transformation-specific domain. The relative frequency of ETV6-related thrombocytopenia was 2.6% in the whole case series and 4.6% among the families with known forms of inherited thrombocytopenia. The degree of thrombocytopenia and bleeding tendency of the patients with ETV6-related thrombocytopenia were mild, but four subjects developed B-cell acute lymphoblastic leukemia during childhood, resulting in a significantly higher incidence of this condition compared to that in the general population. Clinical and laboratory findings did not identify any particular defects that could lead to the suspicion of this disorder from the routine diagnostic workup. However, at variance with most inherited thrombocytopenias, platelets were not enlarged. In vitro studies revealed that the maturation of the patients’ megakaryocytes was defective and that the patients have impaired proplatelet formation. Moreover, platelets from patients with ETV6-related thrombocytopenia have reduced ability to spread on fibrinogen. Since the dominant thrombocytopenias due to mutations in RUNX1 and ANKRD26 are also characterized by normal platelet size and predispose to hematologic malignancies, we suggest that screening for ETV6, RUNX1 and ANKRD26 mutations should be performed in all subjects with autosomal dominant thrombocytopenia and normal platelet size. PMID:27365488

  4. A Joint Interactive Storybook Intervention Program for Preschool and Kindergarten Children

    Science.gov (United States)

    Vaknin-Nusbaum, Vered; Nevo, Einat

    2017-01-01

    The effectiveness of a joint interactive storybook reading program delivered by class teachers to develop literacy skills is examined in Hebrew-speaking preschool and kindergarten children. Post-intervention, both groups achieved significantly higher gains in language and print concept skills than age-matched comparison groups that did not have…

  5. 75 FR 32535 - ITS Joint Program Office; IntelliDriveSM

    Science.gov (United States)

    2010-06-08

    ... DEPARTMENT OF TRANSPORTATION ITS Joint Program Office; IntelliDrive\\SM\\ Deployment Scenarios Workshop; Notice of Workshop AGENCY: Research and Innovative Technology Administration, Department of... participants to identify advantages and disadvantages of each of the draft scenarios and critical policy and...

  6. 76 FR 72493 - ITS Joint Program Office Webinar on Alternative Organizational Structures for a Certificate...

    Science.gov (United States)

    2011-11-23

    ... organizational structures for a certificate management entity (CME) to support a trusted and secure connected... DEPARTMENT OF TRANSPORTATION ITS Joint Program Office Webinar on Alternative Organizational... Adam Hopps at (202) 680-0091. The ITS JPO will present results from an early analysis of organizational...

  7. F-35 Lightning II Joint Strike Fighter (JSF) Program: Background, Status, and Issues

    National Research Council Canada - National Science Library

    Bolkcom, Christopher; Murch, Anthony

    2008-01-01

    The Defense Department's F-35 Lightning II Joint Strike Fighter (JSF) is one of three aircraft modernization programs in tactical aviation, the others being the Air Force F-22A fighter and the Navy F/A-18E/F fighter/attack plane...

  8. F-35 Lightning II Joint Strike Fighter "JSF" Program: Background, Status, and Issues

    National Research Council Canada - National Science Library

    Murch, Anthony; Bolkcom, Christopher

    2007-01-01

    The Defense Department's F-35 Lightning II Joint Strike Fighter (JSF) is one of three aircraft modernization programs in tactical aviation, the others being the Air Force F-22A fighter and the Navy F/A-18E/F fighter/attack plane...

  9. F-35 Lightning II Joint Strike Fighter (JSF) Program: Background, Status, and Issues

    National Research Council Canada - National Science Library

    Bolkcom, Christopher

    2009-01-01

    The Defense Department's F-35 Lightning II Joint Strike Fighter (JSF) is one of three aircraft modernization programs in tactical aviation, the others being the Air Force F-22A fighter and the Navy F/A-18E/F fighter/attack plane...

  10. 75 FR 56651 - ITS Joint Program Office; Trucking Industry Mobility & Technology Coalition Annual Meeting

    Science.gov (United States)

    2010-09-16

    ... DEPARTMENT OF TRANSPORTATION ITS Joint Program Office; Trucking Industry Mobility & Technology... Transportation. ACTION: Notice. The Trucking Industry Mobility & Technology Coalition (TIMTC) Annual [[Page 56652...: Beating Gridlock with a Smart Grid; U.S. DOT Truck Technology Initiatives; and State and Federal...

  11. A two-stage inexact joint-probabilistic programming method for air quality management under uncertainty.

    Science.gov (United States)

    Lv, Y; Huang, G H; Li, Y P; Yang, Z F; Sun, W

    2011-03-01

    A two-stage inexact joint-probabilistic programming (TIJP) method is developed for planning a regional air quality management system with multiple pollutants and multiple sources. The TIJP method incorporates the techniques of two-stage stochastic programming, joint-probabilistic constraint programming and interval mathematical programming, where uncertainties expressed as probability distributions and interval values can be addressed. Moreover, it can not only examine the risk of violating joint-probability constraints, but also account for economic penalties as corrective measures against any infeasibility. The developed TIJP method is applied to a case study of a regional air pollution control problem, where the air quality index (AQI) is introduced for evaluation of the integrated air quality management system associated with multiple pollutants. The joint-probability exists in the environmental constraints for AQI, such that individual probabilistic constraints for each pollutant can be efficiently incorporated within the TIJP model. The results indicate that useful solutions for air quality management practices have been generated; they can help decision makers to identify desired pollution abatement strategies with minimized system cost and maximized environmental efficiency. Copyright © 2010 Elsevier Ltd. All rights reserved.

  12. Assessment of the Accounting and Joint Accounting/Computer Information Systems Programs.

    Science.gov (United States)

    Appiah, John; Cernigliaro, James; Davis, Jeffrey; Gordon, Millicent; Richards, Yves; Santamaria, Fernando; Siegel, Annette; Lytle, Namy; Wharton, Patrick

    This document presents City University of New York LaGuardia Community College's Department of Accounting and Managerial Studies assessment of its accounting and joint accounting/computer information systems programs report, and includes the following items: (1) description of the mission and goals of the Department of Accounting and Managerial…

  13. The joint EC/EPA mid-Connecticut test program

    International Nuclear Information System (INIS)

    Kilgroe, J.D.; Brna, T.G.

    1991-01-01

    In early 1989, Environment Canada and the U.S. Environmental Protection Agency sponsored a comprehensive test program on a refuse-derived fuel (RDF) unit of the Mid-Connecticut facility in Hartford. The program, conducted in cooperation with the Connecticut Resource Recovery Authority (CRRA), the facility's operator, included characterization and performance test phases. The results of the characterization tests were used in defining both the combustion and flue gas cleaning system operating conditions for the performance tests. The results of the performance tests are emphasized in this paper and are summarized in three parts. First, the combustion tests results will be addressed and related to good combustion practice for RDF combustors. Then, the performance of the lime spray dryer absorber/fabric filter system in controlling acid gas (hydrogen chloride, sulfur dioxide), trace organic [polychlorinated dibenzodioxin (PCDD) and polychlorinated dibenzofuran (PCDF)], trace metal [arsenic (as), cadmium (Cd), chromium (Cr), lead (Pb), mercury (Hg), nickel (Ni), and zinc (Zn)], and particulate matter (PM) emissions will be discussed. Finally, the results of ash/residue analyses will be presented

  14. LMFBR flexible pipe joint development program. Annual technical progress report, government fiscal year 1977

    International Nuclear Information System (INIS)

    1978-01-01

    Currently, the ASME Boiler and Pressure Vessel Code does not allow the use of flexible pipe joints (bellows) in Section III, Class 1 reactor primary piping systems. Studies have shown that the primary piping loops of LMFBR's could be simplified by using these joints. This simplification translates directly into shorter primary piping runs and reduced costs for the primary piping system. Further cost savings result through reduced vault sizes and reduced containment building diameter. In addition, the use of flexible joints localizes the motions from thermally-induced piping growth into components which are specifically designed to accommodate this motion. This reduces the stress levels in the piping system and its components. It is thus economically and structurally important that flexible piping joints be available to the LMFBR designer. The overall objective of the Flexible Joint Program is to provide this availability. This will be accomplished through the development of ASME rules which allow the appropriate use of such joints in Section III, Class 1 piping systems and through the development and demonstration of construction methods which satisfy these rules. The rule development includes analytic and testing methodology formulations which will be supported by subscale bellows testing. The construction development and demonstration encompass the design, fabrication, and in-sodium testing of prototypical LMFBR plant-size flexible pipe joints which meet all ASME rule requirements. The satisfactory completion of these developmental goals will result in an approved flexible pipe joint design for the LMFBR. Progress is summarized in the following efforts undertaken during 1977 to accomplish these goals: (1) code case support, (2) engineering and design, (3) material development, (4) testing, and (5) manufacturing development

  15. Effects of an intensive weight loss program on knee joint loading in obese adults with knee osteoarthritis

    DEFF Research Database (Denmark)

    Aaboe, J; Bliddal, H; Messier, S P

    2011-01-01

    To determine the effect of an intensive weight loss program on knee joint loads during walking in obese patients with knee osteoarthritis (OA).......To determine the effect of an intensive weight loss program on knee joint loads during walking in obese patients with knee osteoarthritis (OA)....

  16. Quality Assurance of Joint Degree Programs from the Perspective of Quality Assurance Agencies: Experience in East Asia

    Science.gov (United States)

    Hou, Yung-Chi; Ince, Martin; Tsai, Sandy; Wang, Wayne; Hung, Vicky; Lin Jiang, Chung; Chen, Karen Hui-Jung

    2016-01-01

    Joint degree programs have gained popularity in East Asia, due to the growth of transnational higher education in the region since 2000. However, the external quality assurance (QA) and accreditation of joint degree programs is a challenge for QA agencies, as it normally involves the engagement of several institutions and multiple national…

  17. The Joint Philosophical Program of Russell and Wittgenstein and Its Demise

    Directory of Open Access Journals (Sweden)

    Nikolay Milkov

    2013-03-01

    Full Text Available Between April and November 1912, Bertrand Russell and Ludwig Wittgenstein were engaged in a joint philosophical program. Wittgenstein’s meeting with Gottlob Frege in December 1912 led, however, to its dissolution—the joint program was abandoned. Section 1 of this paper outlines the key points of that program, identifying what Russell and Wittgenstein each contributed to it. The second section determines precisely those features of their collaborative work that Frege criticized. Finally, building upon the evidence developed in the first two sections, section 3 recasts along previously undeveloped lines Wittgensein’s logical–philosophical discoveries in the two years following his encounter with Frege in 1912. The paper concludes, in section 4, with an overview of the dramatic consequences the Frege–Wittgenstein critique had for Russell’s philosophical development.

  18. YK-4-279 inhibits ERG and ETV1 mediated prostate cancer cell invasion.

    Directory of Open Access Journals (Sweden)

    Said Rahim

    2011-04-01

    Full Text Available Genomic rearrangements involving the ETS family of transcription factors occur in 40-70% of prostate cancer cases. ERG and ETV1 are the most common ETS members observed in these genetic alterations. The high prevalence of these rearrangements and their biological significance represents a novel therapeutic target for the treatment of prostate cancer.We recently reported the development of YK-4-279, a small molecule inhibitor of EWS-FLI1 oncoprotein in Ewing's Sarcoma. Since ERG and ETV1 belong to the same class of ETS factors as FLI1, we tested the ability of YK-4-279 to inhibit biological functions of ERG and ETV1 proteins in prostate cancer. YK-4-279 inhibited ERG and ETV1 mediated transcriptional activity in a luciferase assay. YK-4-279 also decreased ERG and ETV1 downstream target mRNA and protein expression in ETV1-fusion positive LNCaP and ERG fusion positive VCaP cells. YK-4-279 reduced the motility of LNCaP cells in a scratch assay and the invasive phenotype of both LNCaP and VCaP cells in a HUVEC invasion assay. Fusion-negative PC3 cells were unresponsive to YK-4-279. SiRNA mediated ERG knockdown in VCaP cells resulted in a loss of drug responsiveness. Concurrently, transient ERG expression in PC-3 cells resulted in increased invasive potential, which was reduced by YK-4-279.These data demonstrate that YK-4-279 inhibits ERG and ETV1 biological activity in fusion-positive prostate cancer cells leading to decreased motility and invasion. Therefore, YK-4-279 may have an impact on metastasis in prostate cancer and it may be further evaluated for its clinical applications in prostate cancer in addition to Ewing's sarcoma.

  19. RNF4 interacts with multiSUMOylated ETV4.

    Science.gov (United States)

    Aguilar-Martinez, Elisa; Guo, Baoqiang; Sharrocks, Andrew D

    2016-01-01

    Protein SUMOylation represents an important regulatory event that changes the activities of numerous proteins. Recent evidence demonstrates that polySUMO chains can act as a trigger to direct the ubiquitin ligase RNF4 to substrates to cause their turnover through the ubiquitin pathway. RNF4 uses multiple SUMO interaction motifs (SIMs) to bind to these chains. However, in addition to polySUMO chains, a multimeric binding surface created by the simultaneous SUMOylation of multiple residues on a protein or complex could also provide a platform for the recruitment of multi-SIM proteins like RNF4. Here we demonstrate that multiSUMOylated ETV4 can bind to RNF4 and that a unique combination of SIMs is required for RNF4 to interact with this multiSUMOylated platform. Thus RNF4 can bind to proteins that are either polySUMOylated through a single site or multiSUMOylated on several sites and raises the possibility that such multiSIM-multiSUMO interactions might be more widespread.

  20. FAA/NASA Joint University Program for Air Transportation Research, 1992-1993

    Science.gov (United States)

    Morrell, Frederick R. (Compiler)

    1994-01-01

    The research conducted during the academic year 1992-1993 under the FAA/NASA sponsored Joint University Program for Air Transportation Research is summarized. The year end review was held at Ohio University, Athens, Ohio, 17-18 June 1993. The Joint University Program is a coordinated set of three grants sponsored by the Federal Aviation Administration and NASA Langley Research Center, one each with the Massachusetts Institute of Technology, Ohio University, and Princeton University. Completed works, status reports, and annotated bibliographies are presented for research topics, which include navigation, guidance, and control theory and practice, aircraft performance, human factors and air traffic management. An overview of the year's activities for each university is also presented.

  1. FAA/NASA Joint University Program for Air Transportation Research: 1993-1994

    Science.gov (United States)

    Hueschen, Richard M. (Compiler)

    1995-01-01

    This report summarizes the research conducted during the academic year 1993-1994 under the NASA/FAA sponsored Joint University Program for Air Transportation Research. The year end review was held at Ohio University, Athens, Ohio, July 14-15, 1994. The Joint University Program is a coordinated set of three grants sponsored by NASA Langley Research Center and the Federal Aviation Administration, one each with the Massachusetts Institute of Technology (NGL-22-009-640), Ohio University (NGR-36-009-017), and Princeton University (NGL-31-001-252). Completed works, status reports, and annotated bibliographies are presented for research topics which include navigation, guidance and control theory and practice, aircraft performance, human factors, and expert systems concepts applied to aircraft and airport operations. An overview of the year's activities for each university is also presented.

  2. Joint MS Degree Program between the Korea University of Technology and Education and the University of Kansas

    Science.gov (United States)

    Dougherty, R. L.; Kim, Kwang Su

    This paper provides an overview of the Joint MS Degree Program between Korea University of Technology and Education’ s (KUT) Mechatronics Department and Kansas University’ s (KU) Mechanical Engineering Department. Discussions were initiated in early 2005 which resulted in a formal agreement being approved by both parties in mid-2007. The Joint MS Degree Program is composed of 30 semester credit hours, equally split between the two universities, with the actual degree being awarded by the institution at which the thesis work is performed. Issues addressed during the development of this Joint MS Program included: joint versus dual degrees, institutional acceptance of the transfer of fifteen hours of credit for an MS degree, different admissions requirements and procedures for the two institutions, financial support of the students, faculty advisors at each institution, Graduate Directors at each institution, transcript acknowledgement of the Joint Degree, residency requirements, English speaking requirements/abilities, thesis publication allowances/requirements, and time zone differences for virtual meetings. These issues have been addressed, and the Joint MS Degree Program is functioning with a small number of students having taken advantage of the opportunity since the Program’ s inception. Future considerations are: growing the number of students in the Program, expansion to other Departments besides KU-Mechanical Engineering and KUTMechatronics, including other universities in the Program, expansion to a Joint PhD Degree Program, and stronger funding resources.

  3. ETV6-NTRK3 as a therapeutic target of small molecule inhibitor PKC412

    Energy Technology Data Exchange (ETDEWEB)

    Chi, Hoang Thanh, E-mail: kk086406@mgs.k.u-tokyo.ac.jp [Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo 108-8639 (Japan); Ly, Bui Thi Kim [Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo 108-8639 (Japan); Kano, Yasuhiko [Division of Hematology and Medical Oncology, Tochigi Cancer Center, Tochigi 321-0293 (Japan); Tojo, Arinobu [Division of Molecular Therapy, Department of Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of Tokyo, Tokyo (Japan); Watanabe, Toshiki [Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo 108-8639 (Japan); Sato, Yuko [Musashimurayama Hospital, Musashimurayama, Tokyo 208-0011 (Japan)

    2012-12-07

    Highlights: Black-Right-Pointing-Pointer ETV6-NTRK3 is an oncogene with transformation activity in multiple cell lineages. Black-Right-Pointing-Pointer PKC412 could block ETV6-NTRK3 activation. Black-Right-Pointing-Pointer Loss of ETV6-NTRK3 phosphorylation leads to inactivation of its downstream signaling pathway. Black-Right-Pointing-Pointer Inhibition of ETV6-NTRK3 activation by PKC412 could be a novel strategy for the treatment. -- Abstract: The ETV6-NTRK3 (EN) fusion gene which encodes a chimeric tyrosine kinase was first identified by cloning of the t(12;15)(p13;q25) translocation in congenital fibrosarcoma (CFS). Since then, EN has been also found in congenital mesoblastic nephroma (CMN), secretory breast carcinoma (SBC) and acute myelogenous leukemia (AML). Using IMS-M2 and M0-91 cell lines harboring the EN fusion gene, and Ba/F3 cells stably transfected with EN, we demonstrated that PKC412, also known as midostaurin, is an inhibitor of EN. Inhibition of EN activity by PKC412 suppressed the activity of it downstream molecules leading to inhibition of cell proliferation and induction of apoptosis. Our data for the first time suggested that PKC412 could serve as therapeutic drug for treatment of patients with this fusion.

  4. ETV6–NTRK3 as a therapeutic target of small molecule inhibitor PKC412

    International Nuclear Information System (INIS)

    Chi, Hoang Thanh; Ly, Bui Thi Kim; Kano, Yasuhiko; Tojo, Arinobu; Watanabe, Toshiki; Sato, Yuko

    2012-01-01

    Highlights: ► ETV6–NTRK3 is an oncogene with transformation activity in multiple cell lineages. ► PKC412 could block ETV6–NTRK3 activation. ► Loss of ETV6–NTRK3 phosphorylation leads to inactivation of its downstream signaling pathway. ► Inhibition of ETV6–NTRK3 activation by PKC412 could be a novel strategy for the treatment. -- Abstract: The ETV6–NTRK3 (EN) fusion gene which encodes a chimeric tyrosine kinase was first identified by cloning of the t(12;15)(p13;q25) translocation in congenital fibrosarcoma (CFS). Since then, EN has been also found in congenital mesoblastic nephroma (CMN), secretory breast carcinoma (SBC) and acute myelogenous leukemia (AML). Using IMS-M2 and M0–91 cell lines harboring the EN fusion gene, and Ba/F3 cells stably transfected with EN, we demonstrated that PKC412, also known as midostaurin, is an inhibitor of EN. Inhibition of EN activity by PKC412 suppressed the activity of it downstream molecules leading to inhibition of cell proliferation and induction of apoptosis. Our data for the first time suggested that PKC412 could serve as therapeutic drug for treatment of patients with this fusion.

  5. ETV4 and Myeov knockdown impairs colon cancer cell line proliferation and invasion

    International Nuclear Information System (INIS)

    Moss, Alan C.; Lawlor, Garrett; Murray, David; Tighe, Donal; Madden, Stephen F.; Mulligan, Anne-Marie; Keane, Conor O.; Brady, Hugh R.; Doran, Peter P.; MacMathuna, Padraic

    2006-01-01

    We have identified novel colorectal cancer-associated genes using NCBI's UNIGENE cDNA libraries. Colon cancer libraries were examined using Digital Differential Display and disease-associated genes were selected. Among these were ETV4 and MYEOV, novel colorectal cancer-associated genes. Samples of matched normal and neoplastic colon were obtained from human subjects and gene expression was quantified using real-time PCR. ETV4 gene expression was significantly increased in colonic neoplasia in comparison to matched normal colonic tissue (p < 0.05). Myeov expression was also increased in colon neoplasia in comparison to matched normal tissue. The effect of siRNA-mediated knockdown of ETV4 and Myeov on cell proliferation and invasion was assessed. ETV4 knockdown resulted in a 90% decrease in cell proliferation (p < 0.05) and a 67% decrease in cell invasion. Myeov knockdown resulted in a 48% decrease in cell proliferation (p < 0.05) and a 36% decrease in cell invasion. These data suggest that ETV4 and Myeov may provide novel targets for therapeutic intervention

  6. ETV6-RUNX1 Rearrangement in Tunisian Pediatric B-Lineage Acute Lymphoblastic Leukemia

    Directory of Open Access Journals (Sweden)

    Abir Gmidène

    2009-01-01

    Full Text Available In this study, Forty-one out of fifty-seven Tunisian children with B-lineage acute lymphoblastic leukemia (B-ALL, and without cytogenetically detectable recurrent abnormalities at the time of the diagnosis, were evaluated by fluorescence in situ hybridization (FISH for the t(12;21. This translocation leads ETV6-RUNX1 (previously TEL-AML1 fusion gene. 16 patients (28% had ETV6-RUNX1 rearrangement. In addition to this rearrangement, two cases showed a loss of the normal ETV6 allele, and three others showed an extra signal of the RUNX1 gene. Seven patients without ETV6-RUNX1 rearrangement showed extra signals of the RUNX1 gene. One out of the 7 patients was also associated with a t(3;12 identified by FISH. This is the first Tunisian study in which we report the incidence of t(12;21 among childhood B-lineage ALL and in which we have found multiple copies of RUNX1. Finally, our findings confirm that additional or secondary genetic changes are commonly encountered in pediatric B-lineage ALL with ETV6-RUNX1 gene fusion which is envisaged to play a pivotal role in disease progression.

  7. A Double Negative Loop Comprising ETV6/RUNX1 and MIR181A1 Contributes to Differentiation Block in t(12;21-Positive Acute Lymphoblastic Leukemia.

    Directory of Open Access Journals (Sweden)

    Yung-Li Yang

    Full Text Available Childhood acute lymphoblastic leukemia (ALL with t(12;21, which results in expression of the ETV6/RUNX1 fusion gene, is the most common chromosomal lesion in precursor-B (pre-B ALL. We identified 17 microRNAs that were downregulated in ETV6/RUNX1+ compared with ETV6/RUNX1- clinical samples. Among these microRNAs, miR-181a-1 was the most significantly reduced (by ~75%; P < 0.001. Using chromatin immunoprecipitation, we demonstrated that ETV6/RUNX1 directly binds the regulatory region of MIR181A1, and knockdown of ETV6/RUNX1 increased miR-181a-1 level. We further showed that miR-181a (functional counterpart of miR-181a-1 could target ETV6/RUNX1 and cause a reduction in the level of the oncoprotein ETV6/RUNX1, cell growth arrest, an increase in apoptosis, and induction of cell differentiation in ETV6/RUNX1+ cell line. Moreover, ectopic expression of miR-181a also resulted in decreased CD10 hyperexpression in ETV6/RUNX1+ primary patient samples. Taken together, our results demonstrate that MIR181A1 and ETV6/RUNX1 regulate each other, and we propose that a double negative loop involving MIR181A1 and ETV6/RUNX1 may contribute to ETV6/RUNX1-driven arrest of differentiation in pre-B ALL.

  8. Toward a joint health and disease management program. Toronto hospitals partner to provide system leadership.

    Science.gov (United States)

    Macleod, Anne Marie; Gollish, Jeffrey; Kennedy, Deborah; McGlasson, Rhona; Waddell, James

    2009-01-01

    The Joint Health and Disease Management Program in the Toronto Central Local Health Integration Network (TC LHIN) is envisioned as a comprehensive model of care for patients with hip and knee arthritis. It includes access to assessment services, education, self-management programs and other treatment programs, including specialist care as needed. As the first phase of this program, the hospitals in TC LHIN implemented a Hip and Knee Replacement Program to focus on improving access and quality of care, coordinating services and measuring wait times for patients waiting for hip or knee replacement surgery. The program involves healthcare providers, consumers and constituent hospitals within TC LHIN. The approach used for this program involved a definition of governance structure, broad stakeholder engagement to design program elements and plans for implementation and communication to ensure sustainability. The program and approach were designed to provide a model that is transferrable in its elements or its entirety to other patient populations and programs. Success has been achieved in creating a single wait list, developing technology to support referral management and wait time reporting, contributing to significant reductions in waits for timely assessment and treatment, building human resource capacity and improving patient and referring physician satisfaction with coordination of care.

  9. SEMTAP (Serpentine End Match TApe program): The Easy Way to Program Your Numerically Controlled Router for the Production of SEM Joints

    Science.gov (United States)

    Ronald E. Coleman

    1977-01-01

    SEMTAP (Serpentine End Match TApe Program) is an easy and inexpensive method of programing a numerically controlled router for the manufacture of SEM (Serpentine End Matching) joints. The SEMTAP computer program allows the user to issue commands that will accurately direct a numerically controlled router along any SEM path. The user need not be a computer programer to...

  10. Russian-U.S. joint program on the safe management of nuclear materials

    International Nuclear Information System (INIS)

    Witmer, F.E.; Krumpe, P.F.; Carlson, D.D.

    1997-12-01

    The Russian-US joint program on the safety of nuclear materials was initiated in response to the 1993 Tomsk-7 accident. The bases for this program are the common technical issues confronting the US and Russia in the safe management of excess weapons grade nuclear materials. The US and Russian weapons dismantlement process is producing hundreds of tons of excess Pu and HEU fissile materials. The US is on a two path approach for disposition of excess Pu: (1) use Pu in existing reactors and/or (2) immobilize Pu in glass or ceramics followed by geologic disposal. Russian plans are to fuel reactors with excess Pu. US and Russia are both converting and blending HEU into LEU for use in existing reactors. Fissile nuclear materials storage, handling, processing, and transportation will be occurring in both countries for tens of years. A table provides a history of the major events comprising the Russian-US joint program on the safety of nuclear materials. A paper delineating program efforts was delivered at the SPECTRUM '96 conference. This paper provides an update on program activities since then

  11. Overview of the joint US/Russia surety program in the Sandia National Laboratories Cooperative Measures Program

    International Nuclear Information System (INIS)

    Smith, R.E.; Vorontsova, O.S.; Blinov, I.M.

    1998-02-01

    Sandia National Laboratories has initiated many joint research and development projects with the two premier Russian nuclear laboratories, VNIIEF and VNIITF, (historically known as Arzamas-16 and Chelyabinsk-70) in a wide spectrum of areas. One of the areas in which critical dialogue and technical exchange is continuing to take place is in the realm of system surety. Activities primarily include either safety or security methodology development, processes, accident environment analyses and testing, accident data-bases, assessments, and product design. Furthermore, a continuing dialog has been established between the organizations with regard to developing a better understanding of how risk is perceived and analyzed in Russia versus that in the US. The result of such efforts could reduce the risk of systems to incur accidents or incidents resulting in high consequences to the public. The purpose of this paper is to provide a current overview of the Sandia surety program and its various initiatives with the Russian institutes, with an emphasis on the program scope and rationale. The historical scope of projects will be indicated. A few specific projects will be discussed, along with results to date. The extension of the joint surety initiatives to other government and industry organizations will be described. This will include the current status of a joint Sandia/VNIIEF initiative to establish an International Surety Center for Energy Intensive and High Consequence Systems and Infrastructures

  12. Overexpression of ETV4 protein in triple-negative breast cancer is associated with a higher risk of distant metastasis

    Directory of Open Access Journals (Sweden)

    Yuan ZY

    2014-09-01

    Full Text Available Zhong-Yu Yuan,1–3,* Ting Dai,1,2,* Shu-Sen Wang,1–3 Rou-Jun Peng,1–3 Xing-Hua Li,1,2 Tao Qin,1–3 Li-Bing Song,1,2 Xi Wang1,2,41State Key Laboratory of Oncology in South China, Guangzhou, People's Republic of China; 2Collaborative Innovation Center for Cancer Medicine, Guangzhou, People's Republic of China; 3Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, People's Republic of China; 4Department of Breast Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, People's Republic of China  *These authors contributed equally to this work Background: Patients with triple-negative breast cancer (TNBC present a higher probability of distant metastasis and lack of effective targeted therapy. ETS translocation variant 4 (ETV4 is an ETS (E-26 transcription factor and has been associated with tumor metastasis. However, the clinical and functional significance of ETV4 in TNBC still remains unclear. Methods: A human tumor metastasis polymerase chain reaction array was used to profile differential expression of tumor metastasis-related genes in TNBC tissue. Real-time reverse transcription and Western blot analyses were performed to verify ETV4 expression in TNBC cells and tissue. Immunohistochemistry was used to detect expression of ETV4 protein in 135 TNBC tissue samples for association between ETV4 protein expression and clinical outcomes. Results: A total total of eight upregulated (CCL7, KISS1, MET, MMP7, NR4A3, ETV4, TIMP3, and TSHR and three downregulated (ITGA7, SSTR, and MMP2 genes were identified between TNBC tissue and the luminal subtype of breast cancer tissue. ETV4 messenger ribonucleic acid was more than five-fold upregulated in TNBC tissue compared with the control tissue. ETV4 overexpression was found in 57.0% of 135 TNBC cases. Overexpression of ETV4 protein was associated with an advanced stage and a higher proportion of positive lymph node and lymphovascular invasion. Patients with an ETV4

  13. The Effectiveness of a Joint Attention Training Program on Improving Communication Skills of Children with Autism Spectrum Disorder

    Science.gov (United States)

    Eissa, Mourad Ali

    2015-01-01

    The purpose of this study was to explore the effect of a joint attention intervention program on improving joint attention and communication skills in children with autism disorder. Participants were ten children between the ages of five and seven who attended a school for children with developmental disabilities (Tarbya Fekrya ). A pre-post…

  14. ETV6/RUNX1 Induces Reactive Oxygen Species and Drives the Accumulation of DNA Damage in B Cells

    Directory of Open Access Journals (Sweden)

    Hans-Peter Kantner

    2013-11-01

    Full Text Available The t(12;21(p13;q22 chromosomal translocation is the most frequent translocation in childhood B cell precursor-acute lymphoblastic leukemia and results in the expression of an ETV6/RUNX1 fusion protein. The frequency of ETV6/RUNX1 fusions in newborns clearly exceeds the leukemia rate revealing that additional events occur in ETV6/RUNX1-positive cells for leukemic transformation. Hitherto, the mechanisms triggering these second hits remain largely elusive. Thus, we generated a novel ETV6/RUNX1 transgenic mouse model where the expression of the fusion protein is restricted to CD19+ B cells. These animals harbor regular B cell development and lack gross abnormalities. We established stable pro-B cell lines carrying the ETV6/RUNX1 transgene that allowed us to investigate whether ETV6/RUNX1 itself favors the acquisition of second hits. Remarkably, these pro-B cell lines as well as primary bone marrow cells derived from ETV6/RUNX1 transgenic animals display elevated levels of reactive oxygen species (ROS as tested with ETV6/RUNX1 transgenic dihydroethidium staining. In line, intracellular phospho-histone H2AX flow cytometry and comet assay revealed increased DNA damage indicating that ETV6/RUNX1 expression enhances ROS. On the basis of our data, we propose the following model: the expression of ETV6/RUNX1 creates a preleukemic clone and leads to increased ROS levels. These elevated ROS favor the accumulation of secondary hits by increasing genetic instability and doublestrand breaks, thus allowing preleukemic clones to develop into fully transformed leukemic cells.

  15. EU program fuel cells in 2012 - FCH JU Fuel Cell and Hydrogen Joint Undertaking; EU-program braensleceller 2012 - FCH JU Fuel Cell and Hydrogen Joint Undertaking

    Energy Technology Data Exchange (ETDEWEB)

    Ridell, Bengt

    2013-03-15

    An EU activity in fuel cell and hydrogen field are gathered since 2008 in a so called JU, Joint Undertaking, or as it is also referred to as JTI Joint Technology Initiative. The program will run 2008 - 2013 and covers in total 940 MEUR of which the EU Commission is funding 470 MEUR. The activities of the FCH JU are governed by a Governing Board which has 12 members, five from the Commission, one of the research group and 5 from the Industrial Group. The current agreement for the FCH JU / JTI is coming to an end, and the sixth and final call was released in January 2013 with the deadline of 22 May 2013. Funding from the Commission is made through the Seventh Framework Programme FP7, which ends in 2013. Next the Eighth Framework Programme called Horizon 2020 shall continue for the years 2014 - 2020. Five of the six calls are completed. From the four first calls there are 61 projects started which 6 have been completed. From the fifth announcement is further 27 projects selected for negotiation with the Commission and they will start soon. It is now working intensively to plan Horizon 2020. There are plans to continue the new FCH JU but nothing is decided either for this or for the budget for Horizon 2020. If the FCH Joint Undertaking shall continue in its present form as a Joint Undertaking it will require clear long-term commitments from the private sector and also from the Member States. Another issue is that the long-term research should also get space it has not been the case in the present FCH JU. There are several Swedish participants in the projects and in the working groups of the program. There are Swedish participants in 11 of the 68 projects launched so far. It is in the areas of Stationary systems, Transportation and Early Markets. Project manager for the project FCGEN is Volvo Technology AB. FCH JU has its own website, www.fch-ju.eu, which opened in 2010 when the organization of the program was taken over from the Commission to permanent organisation

  16. Russia-U.S. joint program on the safe management of nuclear materials

    International Nuclear Information System (INIS)

    Witmer, F.E.; Krumpe, P.F.; Carlson, D.D.

    1998-06-01

    The Russia-US joint program on the safe management of nuclear materials was initiated to address common technical issues confronting the US and Russia in the management of excess weapons grade nuclear materials. The program was initiated after the 1993 Tomsk-7 accident. This paper provides an update on program activities since 1996. The Fourth US Russia Nuclear Materials Safety Management Workshop was conducted in March 1997. In addition, a number of contracts with Russian Institutes have been placed by Lawrence Livermore National Laboratory (LLNL) and Sandia National Laboratories (SNL). These contracts support research related to the safe disposition of excess plutonium (Pu) and highly enriched uranium (HEU). Topics investigated by Russian scientists under contracts with SNL and LLNL include accident consequence studies, the safety of anion exchange processes, underground isolation of nuclear materials, and the development of materials for the immobilization of excess weapons Pu

  17. AAV-mediated gene transfer of the obesity-associated gene Etv5 in rat midbrain does not affect energy balance or motivated behavior.

    Directory of Open Access Journals (Sweden)

    Arjen J Boender

    Full Text Available Several genome-wide association studies have implicated the transcription factor E-twenty- six version 5 (Etv5 in the regulation of body mass index. Further substantiating the role of Etv5 in feeding behavior are the findings that targeted disruption of Etv5 in mice leads to decreased body weight gain and that expression of Etv5 is decreased in the ventral tegmental area and substantia nigra pars compacta (VTA/SNpc after food restriction. As Etv5 has been suggested to influence dopaminergic neurotransmission by driving the expression of genes that are responsible for the synthesis and release of dopamine, we investigated if expression levels of Etv5 are dependent on nutritional state and subsequently influence the expression levels of tyrosine hydroxylase. While it was shown that Etv5 expression in the VTA/SNpc increases after central administration of leptin and that Etv5 was able to drive expression of tyrosine hydroxylase in vitro, AAV-mediated gene transfer of Etv5 into the VTA/SNpc of rats did not alter expression of tyrosine hydroxylase in vivo. Moreover, AAV-mediated gene transfer of Etv5 in the VTA/SNpc did not affect measures of energy balance or performances in a progressive ratio schedule. Thus, these data do not support a role for increased expression of Etv5 in the VTA/SNpc in the regulation of feeding behavior.

  18. A Double Negative Loop Comprising ETV6/RUNX1 and MIR181A1 Contributes to Differentiation Block in t(12;21)-Positive Acute Lymphoblastic Leukemia.

    Science.gov (United States)

    Yang, Yung-Li; Yen, Ching-Tzu; Pai, Chen-Hsueh; Chen, Hsuan-Yu; Yu, Sung-Liang; Lin, Chien-Yu; Hu, Chung-Yi; Jou, Shiann-Tarng; Lin, Dong-Tsamn; Lin, Shu-Rung; Lin, Shu-Wha

    2015-01-01

    Childhood acute lymphoblastic leukemia (ALL) with t(12;21), which results in expression of the ETV6/RUNX1 fusion gene, is the most common chromosomal lesion in precursor-B (pre-B) ALL. We identified 17 microRNAs that were downregulated in ETV6/RUNX1+ compared with ETV6/RUNX1- clinical samples. Among these microRNAs, miR-181a-1 was the most significantly reduced (by ~75%; P regulatory region of MIR181A1, and knockdown of ETV6/RUNX1 increased miR-181a-1 level. We further showed that miR-181a (functional counterpart of miR-181a-1) could target ETV6/RUNX1 and cause a reduction in the level of the oncoprotein ETV6/RUNX1, cell growth arrest, an increase in apoptosis, and induction of cell differentiation in ETV6/RUNX1+ cell line. Moreover, ectopic expression of miR-181a also resulted in decreased CD10 hyperexpression in ETV6/RUNX1+ primary patient samples. Taken together, our results demonstrate that MIR181A1 and ETV6/RUNX1 regulate each other, and we propose that a double negative loop involving MIR181A1 and ETV6/RUNX1 may contribute to ETV6/RUNX1-driven arrest of differentiation in pre-B ALL.

  19. FAA/NASA Joint University Program for Air Transportation Research 1994-1995

    Science.gov (United States)

    Remer, J. H.

    1998-01-01

    The Joint University Program for Air Transportation Research (JUP) is a coordinated set of three grants co-sponsored by the Federal Aviation Administration (FAA) and the National Aeronautics and Space Administration (NASA). Under JUP, three institutions: the Massachusetts Institute of Technology, Princeton, and Ohio Universities receive research grants and collaborate with FAA and NASA in defining and performing civil aeronautics research in a multitude of areas. Some of these disciplines are artificial intelligence, control theory, atmospheric hazards, navigation, avionics, human factors, flight dynamics, air traffic management, and electronic communications.

  20. Redesigning a joint replacement program using Lean Six Sigma in a Veterans Affairs hospital.

    Science.gov (United States)

    Gayed, Benjamin; Black, Stephen; Daggy, Joanne; Munshi, Imtiaz A

    2013-11-01

    In April 2009, an analysis of joint replacement surgical procedures at the Richard L. Roudebush Veterans Affairs Medical Center, Indianapolis, Indiana, revealed that total hip and knee replacements incurred $1.4 million in non-Veterans Affairs (VA) care costs with an average length of stay of 6.1 days during fiscal year 2008. The Joint Replacement Program system redesign project was initiated following the Vision-Analysis-Team-Aim-Map-Measure-Change-Sustain (VA-TAMMCS) model to increase efficiency, decrease length of stay, and reduce non-VA care costs. To determine the effectiveness of Lean Six Sigma process improvement methods applied in a VA hospital. Perioperative processes for patients undergoing total joint replacement were redesigned following the VA-TAMMCS model--the VA's official, branded method of Lean Six Sigma process improvement. A multidisciplinary team including the orthopedic surgeons, frontline staff, and executive management identified waste in the current processes and initiated changes to reduce waste and increase efficiency. Data collection included a 1-year baseline period and a 20-month sustainment period. The primary endpoint was length of stay; a secondary analysis considered non-VA care cost reductions. Length of stay decreased 36% overall, decreasing from 5.3 days during the preproject period to 3.4 days during the 20-month sustainment period (P Lean and Six Sigma process improvement initiatives in a surgical practice, producing a 36% sustained reduction in length of stay and completely eliminating non-VA care for total hip and knee replacements while increasing total joint replacement volume at this medical center.

  1. Frequency and clinical impact of ETV6/RUNX1, AF4‑MLL, and BCR ...

    African Journals Online (AJOL)

    Background: Variations in disease presentation and outcome of leukemia treatment has been associated with the presence of certain mutant genes. Three major translocations (ETV6‑RUNX1, BCR‑ABL, and AF4‑MLL) in acute lymphoblastic leukemia (ALL) have been shown to affect treatment outcome. This study is aimed ...

  2. Frequency and clinical impact of ETV6/RUNX1, AF4‑MLL, and BCR ...

    African Journals Online (AJOL)

    2015-05-12

    May 12, 2015 ... features of prognostic importance, which include total white blood cell count (P = 0.416) and FAB subtype (P = 0.576). Conclusion: Presence of fusion ... Frequency and clinical impact of ETV6/RUNX1, AF4‑MLL, and BCR/ABL fusion ... define distinct clinic‑pathological subgroups and have been used in risk ...

  3. The coach program - a "joint" approach to patient education and support.

    Science.gov (United States)

    Shaked, Yael; Dickson, Patricia; Workman, Kathy

    2016-12-01

    Hospital lengths of stay for orthopaedic procedures are declining internationally. Discharge home from hospital following total joint replacement surgery can be stressful due to pain and physical restrictions. Thus, many patients report experiencing increased anxiety and feeling a sudden withdrawal of support from their medical team. The Coach Program maximizes human resources and family-centred care by formally integrating an individual whom the patient identifies as their primary support into their health care team. This unique and innovative program was designed to decrease patient anxiety, increase patient confidence, enhance coping with shorter hospital lengths of stay, and smooth the discharge planning process. Anecdotal feedback from patients and staff has been overwhelmingly positive. A pilot self-reported patient survey was conducted. Future steps include distribution and analysis of a more detailed survey to a broader patient population and finding ways to address the needs of patients with limited social support. Copyright © 2016 Elsevier Inc. All rights reserved.

  4. Joint Task Force on Undergraduate Physics Programs: Implications for physics programs and why you should care

    Science.gov (United States)

    Hodapp, Theodore

    2016-03-01

    The content of undergraduate physics programs has not changed appreciably in 50 years, however, the jobs our students take have changed dramatically. Preparing students for careers they are likely to encounter requires physics programs to rethink and in some cases retool to provide an education that will not only educate an individual in the habits of mind and keen sense of how to solve complex technical problems, but also what related skills they will need to be effective in those careers. Do you teach your student how to read or create a budget? How about dealing with a low-performing member of an R&D team? This talk will explore driving forces behind this report, potential implications for physics departments, and practical steps faculty members can take to continue to consider improvements in experiences for our students. This work is supported in part by the National Science Foundation (NSF-1540570).

  5. Genome‐wide analysis of cytogenetic aberrations in ETV6/RUNX1‐positive childhood acute lymphoblastic leukaemia

    DEFF Research Database (Denmark)

    Borst, Louise; Wesolowska, Agata; Joshi, Tejal

    2012-01-01

    The chromosomal translocation t(12;21) resulting in the ETV6/RUNX1 fusion gene is the most frequent structural cytogenetic abnormality among patients with childhood acute lymphoblastic leukaemia (ALL). We investigated 62 ETV6/RUNX1‐positive childhood ALL patients by single nucleotide polymorphism...... childhood ALL, which may be important for understanding poor responses among this otherwise highly curable subset of ALL and lead to novel targeted treatment strategies....

  6. Ret and Etv4 Promote Directed Movements of Progenitor Cells during Renal Branching Morphogenesis.

    Directory of Open Access Journals (Sweden)

    Paul Riccio

    2016-02-01

    Full Text Available Branching morphogenesis of the epithelial ureteric bud forms the renal collecting duct system and is critical for normal nephron number, while low nephron number is implicated in hypertension and renal disease. Ureteric bud growth and branching requires GDNF signaling from the surrounding mesenchyme to cells at the ureteric bud tips, via the Ret receptor tyrosine kinase and coreceptor Gfrα1; Ret signaling up-regulates transcription factors Etv4 and Etv5, which are also critical for branching. Despite extensive knowledge of the genetic control of these events, it is not understood, at the cellular level, how renal branching morphogenesis is achieved or how Ret signaling influences epithelial cell behaviors to promote this process. Analysis of chimeric embryos previously suggested a role for Ret signaling in promoting cell rearrangements in the nephric duct, but this method was unsuited to study individual cell behaviors during ureteric bud branching. Here, we use Mosaic Analysis with Double Markers (MADM, combined with organ culture and time-lapse imaging, to trace the movements and divisions of individual ureteric bud tip cells. We first examine wild-type clones and then Ret or Etv4 mutant/wild-type clones in which the mutant and wild-type sister cells are differentially and heritably marked by green and red fluorescent proteins. We find that, in normal kidneys, most individual tip cells behave as self-renewing progenitors, some of whose progeny remain at the tips while others populate the growing UB trunks. In Ret or Etv4 MADM clones, the wild-type cells generated at a UB tip are much more likely to remain at, or move to, the new tips during branching and elongation, while their Ret-/- or Etv4-/- sister cells tend to lag behind and contribute only to the trunks. By tracking successive mitoses in a cell lineage, we find that Ret signaling has little effect on proliferation, in contrast to its effects on cell movement. Our results show that Ret/Etv

  7. Oxide dispersion strengthened ferritic steels: a basic research joint program in France

    Energy Technology Data Exchange (ETDEWEB)

    Boutard, J.-L., E-mail: jean-louis.boutard@cea.fr [Cabinet du Haut-Commissaire, CEA/Saclay, 91191 Gif sur Yvette Cedex (France); Badjeck, V. [LPS, UMR CNRS 8502, Building 510, Université Paris-Sud 11, 91405 Orsay Cedex (France); Barguet, L. [LAUM, UMR CNRS 6613, Building IAM – UFR Sciences, Avenue O. Messiaen, 72085 Le Mans Cedex 9 (France); Barouh, C. [DMN/SRMP, CEA/Saclay, Building 520, 91191 Gif sur Yvette Cedex (France); Bhattacharya, A. [DMN/SRMP, CEA/Saclay, Building 520, 91191 Gif sur Yvette Cedex (France); CSNSM, UMR CNRS 8609, Université Paris-Sud 11, Buildings 104 and 108, 91405 Orsay Campus (France); Colignon, Y. [IM2NP, UMR CNRS 7334, Case 142, Faculté des Sciences, Campus de Saint Jérôme, Aix Marseille Université, 13397 Marseille Cedex 20 (France); Hatzoglou, C. [GPM, UMR CNRS 6634, Technopôle du Madrillet, Avenue de l’Université, BP12, 76801 Saint Etienne du Rouvray Cedex (France); Loyer-Prost, M. [DMN/SRMP, CEA/Saclay, Building 520, 91191 Gif sur Yvette Cedex (France); Rouffié, A.L. [DMN/SRMA, CEA/Saclay, Building 455, 91191 Gif sur Yvette Cedex (France); Sallez, N. [SIMAP, UMR CNRS 5266, INPG, Domaine Universitaire, 1130 rue de la Piscine, BP75, 38402 Saint Martin d’Hères Cedex (France); Salmon-Legagneur, H. [DMN/SRMA, CEA/Saclay, Building 455, 91191 Gif sur Yvette Cedex (France); Schuler, T. [DMN/SRMP, CEA/Saclay, Building 520, 91191 Gif sur Yvette Cedex (France)

    2014-12-15

    AREVA, CEA, CNRS, EDF and Mécachrome are funding a joint program of basic research on Oxide Dispersion Strengthened Steels (ODISSEE), in support to the development of oxide dispersion strengthened 9–14% Cr ferritic–martensitic steels for the fuel element cladding of future Sodium-cooled fast neutron reactors. The selected objectives and the results obtained so far will be presented concerning (i) physical–chemical characterisation of the nano-clusters as a function of ball-milling process, metallurgical conditions and irradiation, (ii) meso-scale understanding of failure mechanisms under dynamic loading and creep, and, (iii) kinetic modelling of nano-clusters nucleation and α/α′ unmixing.

  8. An overview of the joint FAA/NASA aircraft/ground runway friction program

    Science.gov (United States)

    Yager, Thomas J.

    1989-01-01

    There is a need for information on runways which may become slippery due to various forms and types of contaminants. Experience has shown that since the beginning of all weather aircraft operations, there have been landing and aborted takeoff incidents and/or accidents each year where aircraft have either run off the end or veered off the shoulder of low friction runways. NASA Langley's Landing and Impact Dynamics Branch is involved in several research programs directed towards obtaining a better understanding of how different tire properties interact with varying pavement surface characteristics to produce acceptable performance for aircraft ground handling requirements. One such effort, which was jointly supported by not only NASA and the FAA but by several aviation industry groups including the Flight Safety Foundation, is described.

  9. Oxide dispersion strengthened ferritic steels: a basic research joint program in France

    Science.gov (United States)

    Boutard, J.-L.; Badjeck, V.; Barguet, L.; Barouh, C.; Bhattacharya, A.; Colignon, Y.; Hatzoglou, C.; Loyer-Prost, M.; Rouffié, A. L.; Sallez, N.; Salmon-Legagneur, H.; Schuler, T.

    2014-12-01

    AREVA, CEA, CNRS, EDF and Mécachrome are funding a joint program of basic research on Oxide Dispersion Strengthened Steels (ODISSEE), in support to the development of oxide dispersion strengthened 9-14% Cr ferritic-martensitic steels for the fuel element cladding of future Sodium-cooled fast neutron reactors. The selected objectives and the results obtained so far will be presented concerning (i) physical-chemical characterisation of the nano-clusters as a function of ball-milling process, metallurgical conditions and irradiation, (ii) meso-scale understanding of failure mechanisms under dynamic loading and creep, and, (iii) kinetic modelling of nano-clusters nucleation and α/α‧ unmixing.

  10. Oxide dispersion strengthened ferritic steels: a basic research joint program in France

    International Nuclear Information System (INIS)

    Boutard, J.-L.; Badjeck, V.; Barguet, L.; Barouh, C.; Bhattacharya, A.; Colignon, Y.; Hatzoglou, C.; Loyer-Prost, M.; Rouffié, A.L.; Sallez, N.; Salmon-Legagneur, H.; Schuler, T.

    2014-01-01

    AREVA, CEA, CNRS, EDF and Mécachrome are funding a joint program of basic research on Oxide Dispersion Strengthened Steels (ODISSEE), in support to the development of oxide dispersion strengthened 9–14% Cr ferritic–martensitic steels for the fuel element cladding of future Sodium-cooled fast neutron reactors. The selected objectives and the results obtained so far will be presented concerning (i) physical–chemical characterisation of the nano-clusters as a function of ball-milling process, metallurgical conditions and irradiation, (ii) meso-scale understanding of failure mechanisms under dynamic loading and creep, and, (iii) kinetic modelling of nano-clusters nucleation and α/α′ unmixing

  11. Somatic drivers of B-ALL in a model of ETV6-RUNX1; Pax5+/− leukemia

    International Nuclear Information System (INIS)

    Weyden, Louise van der; Giotopoulos, George; Wong, Kim; Rust, Alistair G.; Robles-Espinoza, Carla Daniela; Osaki, Hikari; Huntly, Brian J.; Adams, David J.

    2015-01-01

    B-cell precursor acute lymphoblastic leukemia (B-ALL) is amongst the leading causes of childhood cancer-related mortality. Its most common chromosomal aberration is the ETV6-RUNX1 fusion gene, with ~25 % of ETV6-RUNX1 patients also carrying PAX5 alterations. We have recreated this mutation background by inter-crossing Etv6-RUNX1 (Etv6 RUNX1-SB ) and Pax5 +/− mice and performed an in vivo analysis to find driver genes using Sleeping Beauty transposon-mediated mutagenesis and also exome sequencing. Combination of Etv6-RUNX1 and Pax5 +/− alleles generated a transplantable B220 + CD19+ B-ALL with a significant disease incidence. RNA-seq analysis showed a gene expression pattern consistent with arrest at the pre-B stage. Analysis of the transposon common insertion sites identified genes involved in B-cell development (Zfp423) and the JAK/STAT signaling pathway (Jak1, Stat5 and Il2rb), while exome sequencing revealed somatic hotspot mutations in Jak1 and Jak3 at residues analogous to those mutated in human leukemias, and also mutation of Trp53. Powerful synergies exists in our model suggesting STAT pathway activation and mutation of Trp53 are potent drivers of B-ALL in the context of Etv6-RUNX1;Pax5 +/− . The online version of this article (doi:10.1186/s12885-015-1586-1) contains supplementary material, which is available to authorized users

  12. Comprehensive Analysis of ETS Family Members in Melanoma by Fluorescence In Situ Hybridization Reveals Recurrent ETV1 Amplification

    Science.gov (United States)

    Mehra, Rohit; Dhanasekaran, Saravana M; Palanisamy, Nallasivam; Vats, Pankaj; Cao, Xuhong; Kim, Jung H; Kim, David SL; Johnson, Timothy; Fullen, Douglas R; Chinnaiyan, Arul M

    2013-01-01

    E26 transformation-specific (ETS) transcription factors are known to be involved in gene aberrations in various malignancies including prostate cancer; however, their role in melanoma oncogenesis has yet to be fully explored. We have completed a comprehensive fluorescence in situ hybridization (FISH)-based screen for all 27 members of the ETS transcription factor family on two melanoma tissue microarrays, representing 223 melanomas, 10 nevi, and 5 normal skin tissues. None of the melanoma cases demonstrated ETS fusions; however, 6 of 114 (5.3%) melanomas were amplified for ETV1 using a break-apart FISH probe. For the six positive cases, locus-controlled FISH probes revealed that two of six cases were amplified for the ETV1 region, whereas four cases showed copy gains of the entire chromosome 7. The remaining 26 ETS family members showed no chromosomal aberrations by FISH. Quantitative polymerase chain reaction showed an average 3.4-fold (P value = .00218) increased expression of ETV1 in melanomas, including the FISH ETV1-amplified cases, when compared to other malignancies (prostate, breast, and bladder carcinomas). These data suggest that a subset of melanomas overexpresses ETV1 and amplification of ETV1 may be one mechanism for achieving high gene expression. PMID:23908683

  13. Romanian-Canadian joint program for qualification of FCN as a CANDU fuel supplier

    International Nuclear Information System (INIS)

    Galeriu, C.A.; Andrei, G.; Bailescu, A.

    1995-01-01

    target. The experience achieved during this project by all the parts involved ensures a good basis for the next joint programs. (author)

  14. Joint Assessment of ETRR-2 Research Reactor Operations Program, Capabilities, and Facilities

    International Nuclear Information System (INIS)

    Bissani, M; O'Kelly, D S

    2006-01-01

    A joint assessment meeting was conducted at the Egyptian Atomic Energy Agency (EAEA) followed by a tour of Egyptian Second Research Reactor (ETRR-2) on March 22 and 23, 2006. The purpose of the visit was to evaluate the capabilities of the new research reactor and its operations under Action Sheet 4 between the U.S. DOE and the EAEA, ''Research Reactor Operation'', and Action Sheet 6, ''Technical assistance in The Production of Radioisotopes''. Preliminary Recommendations of the joint assessment are as follows: (1) ETRR-2 utilization should be increased by encouraging frequent and sustained operations. This can be accomplished in part by (a) Improving the supply-chain management for fresh reactor fuel and alleviating the perception that the existing fuel inventory should be conserved due to unreliable fuel supply; and (b) Promulgating a policy for sample irradiation priority that encourages the use of the reactor and does not leave the decision of when to operate entirely at the discretion of reactor operations staff. (2) Each experimental facility in operation or built for a single purpose should be reevaluated to focus on those that most meet the goals of the EAEA strategic business plan. Temporary or long-term elimination of some experimental programs might be necessary to provide more focused utilization. There may be instances of emerging reactor applications for which no experimental facility is yet designed or envisioned. In some cases, an experimental facility may have a more beneficial use than the purpose for which it was originally designed. For example, (a) An effective Boron Neutron Capture Therapy (BNCT) program requires nearby high quality medical facilities. These facilities are not available and are unlikely to be constructed near the Inshas site. Further, the BNCT facility is not correctly designed for advanced research and therapy programs using epithermal neutrons. (b) The ETRR-2 is frequently operated to provide color-enhanced gemstones but is

  15. Joint state of Colorado-US Department of Energy WIPP Shipment Exercise Program: TRANSAX '90

    International Nuclear Information System (INIS)

    1990-01-01

    In July 1990, the United States Secretary of Energy requested the DOE conduct a transportation emergency exercise before the end of CY 1990. The tasking was subsequently directed to the Director of DOE's Office of Environmental Restoration and Waste Management (EM) to plan and conduct an exercise, based on a Waste Isolation Pilot Plant (WIPP) shipment scenario. The state of Colorado was asked to participate. Colorado, in turn, invited the DOE to integrate the exercise into its own series of WIPP-related tabletop and field exercises for which the state had already begun planning. The result was a joint USDOE/Colorado full-scale (orientation) exercise called Transportation Accident Exercise 1990 (TRANSAX '90). The state of Colorado's exercise program was a follow-on to previously conducted classroom training. The program would serve to identify and resolve outstanding issues concerning inspections of the WIPP shipment transporter as it entered and passed through the state on the designated Interstate 25 transportation corridor; criteria for movement under various adverse weather and road conditions; and emergency response to accidents occurring in an urban or rural environment. The USDOE designed its participation in the exercise program to test selected aspects of the DOE Emergency Management System relating to response to and management of DOE off-site transportation emergencies involving assistance to state and local emergency response personnel. While a number of issues remain under study for ultimate resolution, others have been resolved and will become the basis for emergency operations plans, SOPs, mutual aid agreements, and checklist upgrades. Concurrently, the concentrated efforts at local, state, and federal levels in dealing with WIPP- related activities during this exercise program development have given renewed impetus to all parties as the beginning of actual shipments draws nearer. Three tabletop scenarios are discussed in this report

  16. A comprehensive joint replacement program for total knee arthroplasty: a descriptive study

    Directory of Open Access Journals (Sweden)

    Prefontaine Paul

    2008-11-01

    Full Text Available Abstract Background Total knee arthroplasty (TKA is a commonly performed surgical procedure in the US. It is important to have a comprehensive inpatient TKA program which maximizes outcomes while minimizing adverse events. The purpose of this study was to describe a TKA program – the Joint Replacement Program (JRP – and report post-surgical outcomes. Methods 74 candidates for a primary TKA were enrolled in the JRP. The JRP was designed to minimize complications and optimize patient-centered outcomes using a team approach including the patient, patient's family, and a multidisciplinary team of health professionals. The JRP consisted of a pre-operative class, standard pathways for medical care, comprehensive peri-operative pain management, aggressive physical therapy (PT, and proactive discharge planning. Measures included functional tests, knee range of motion (ROM, and medical record abstraction of patient demographics, length of stay, discharge disposition, and complications over a 6-month follow-up period. Results All patients achieved medical criteria for hospital discharge. The patients achieved the knee flexion ROM goal of 90° (91.7 ± 5.4°, but did not achieve the knee extension ROM goal of 0° (2.4 ± 2.6°. The length of hospital stay was two days for 53% of the patients, with 39% and 7% discharged in three and four days, respectively. All but three patients were discharged home with functional independence. 68% of these received outpatient physical therapy compared with 32% who received home physical therapy immediately after discharge. Two patients ( Conclusion The comprehensive JRP for TKA was associated with satisfactory clinical outcomes, short lengths of stay, a high percentage of patients discharged home with outpatient PT, and minimal complications. This JRP may represent an efficient, effective and safe protocol for providing care after a TKA.

  17. The effects of adding single-joint exercises to a multi-joint exercise resistance training program on upper body muscle strength and size in trained men.

    Science.gov (United States)

    de França, Henrique Silvestre; Branco, Paulo Alexandre Nordeste; Guedes Junior, Dilmar Pinto; Gentil, Paulo; Steele, James; Teixeira, Cauê Vazquez La Scala

    2015-08-01

    The aim of this study was compare changes in upper body muscle strength and size in trained men performing resistance training (RT) programs involving multi-joint plus single-joint (MJ+SJ) or only multi-joint (MJ) exercises. Twenty young men with at least 2 years of experience in RT were randomized in 2 groups: MJ+SJ (n = 10; age, 27.7 ± 6.6 years) and MJ (n = 10; age, 29.4 ± 4.6 years). Both groups trained for 8 weeks following a linear periodization model. Measures of elbow flexors and extensors 1-repetition maximum (1RM), flexed arm circumference (FAC), and arm muscle circumference (AMC) were taken pre- and post-training period. Both groups significantly increased 1RM for elbow flexion (4.99% and 6.42% for MJ and MJ+SJ, respectively), extension (10.60% vs 9.79%, for MJ and MJ+SJ, respectively), FAC (1.72% vs 1.45%, for MJ and MJ+SJ, respectively), and AMC (1.33% vs 3.17% for MJ and MJ+SJ, respectively). Comparison between groups revealed no significant difference in any variable. In conclusion, 8 weeks of RT involving MJ or MJ+SJ resulted in similar alterations in muscle strength and size in trained participants. Therefore, the addition of SJ exercises to a RT program involving MJ exercises does not seem to promote additional benefits to trained men, suggesting MJ-only RT to be a time-efficient approach.

  18. Joint Commission

    Science.gov (United States)

    ... for the latest publication of The Joint Commission Journal on Quality and Patient Safety (JQPS). . How We Work Process improvement program breeds quality culture, empowers staff An article in Quality Progress, June ...

  19. Joint Assessment of ETRR-2 Research Reactor Operations Program, Capabilities, and Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Bissani, M; O' Kelly, D S

    2006-05-08

    A joint assessment meeting was conducted at the Egyptian Atomic Energy Agency (EAEA) followed by a tour of Egyptian Second Research Reactor (ETRR-2) on March 22 and 23, 2006. The purpose of the visit was to evaluate the capabilities of the new research reactor and its operations under Action Sheet 4 between the U.S. DOE and the EAEA, ''Research Reactor Operation'', and Action Sheet 6, ''Technical assistance in The Production of Radioisotopes''. Preliminary Recommendations of the joint assessment are as follows: (1) ETRR-2 utilization should be increased by encouraging frequent and sustained operations. This can be accomplished in part by (a) Improving the supply-chain management for fresh reactor fuel and alleviating the perception that the existing fuel inventory should be conserved due to unreliable fuel supply; and (b) Promulgating a policy for sample irradiation priority that encourages the use of the reactor and does not leave the decision of when to operate entirely at the discretion of reactor operations staff. (2) Each experimental facility in operation or built for a single purpose should be reevaluated to focus on those that most meet the goals of the EAEA strategic business plan. Temporary or long-term elimination of some experimental programs might be necessary to provide more focused utilization. There may be instances of emerging reactor applications for which no experimental facility is yet designed or envisioned. In some cases, an experimental facility may have a more beneficial use than the purpose for which it was originally designed. For example, (a) An effective Boron Neutron Capture Therapy (BNCT) program requires nearby high quality medical facilities. These facilities are not available and are unlikely to be constructed near the Inshas site. Further, the BNCT facility is not correctly designed for advanced research and therapy programs using epithermal neutrons. (b) The ETRR-2 is frequently operated to

  20. CSPG - SEPM joint convention : Program with abstracts - Sedimentary events and hydrocarbon systems

    International Nuclear Information System (INIS)

    Beauchamp, B.

    1997-01-01

    This joint conference of the Canadian Society of Petroleum Geologists (CSPG) and the Society for Sedimentary Geology (SEPM) was held in Calgary, to encourage collaboration between the petroleum resource industry and academia. Well over 150 papers were presented in various special sessions. The principal topics of discussion included examination, investigation and assessment of the geology, geophysics, geochemistry and the resource potential of sedimentary basins in Canada and around the world. In the course of the presentations the depositional, tectonic and diagenetic histories of various formations, augmented with interpretations of the origin and evolution of the basins were reviewed. The new interpretations were made possible by the new concepts and models of sedimentary geoscience that were born in the creative cauldron of collaboration that exists between industry, government institutions and the universities. The widespread use of modern sequence stratigraphy was used as an example of how scientific and engineering synergy evolved over time to shed new light on the nature of the stratigraphic record. Environmental issues regarding the petroleum industry also received much attention. This volume contains the complete conference program listing, a list of the sponsors and exhibitors, and provides brief abstracts of all papers presented at the conference

  1. "APEC blue"--The effects and implications of joint pollution prevention and control program.

    Science.gov (United States)

    Wang, Hongbo; Zhao, Laijun; Xie, Yujing; Hu, Qingmi

    2016-05-15

    To ensure good air quality in Beijing during Asia-Pacific Economic Cooperation (APEC) China 2014, Beijing and its neighboring five provinces and the associated cities were combined under the Joint Prevention and Control of Atmospheric Pollution (JPCAP) program, which implemented rigorous cooperative emission reduction measures. The program was a unique and large-scale artificial experiment that showed that such measures can achieve excellent results, and it led to the popular "APEC blue" catchphrase (i.e., Beijing's skies became blue as pollution levels decreased). This artificial experiment provided the means to effectively conduct JPCAP strategies in the future. Accordingly, our research focused on the characteristics of the six primary pollutants in Beijing. We found that the JPCAP measures directly reduced concentrations of all pollutants except O3. Through correlation analysis, we found that the band distribution of the cities with strong correlations in PM2.5 and PM10 concentrations was affected by wind conditions. Therefore, JPCAP measures should account for specific seasonal and climatic conditions. Based on cluster analysis using the results from the correlation analysis, we divided 13 cities within a 300-km radius of Beijing into different groups according to the similarity of their PM2.5 and PM10 correlation coefficients. For JPCAP measures relevant to PM2.5 and PM10, we found differences in the degrees of collaboration among cities. Therefore, depending upon the pollutant type, the JPCAP strategy should account for the cities involved, the scope of the core area, and the optimal cities to involve in the collaborative efforts based on cost-effectiveness and collaborative difficulty among the involved cities. Copyright © 2016 Elsevier B.V. All rights reserved.

  2. Joint Attention in Infant-Toddler Early Childhood Programs: Its Dynamics and Potential for Collaborative Learning

    Science.gov (United States)

    Degotardi, Sheila

    2017-01-01

    This article examines how joint attention episodes constitute a core feature of relational pedagogy for infants and toddlers. It draws on social interactionist approaches to language and cognitive development to propose that joint attention may afford significant current and future potential for young children's learning. However, most joint…

  3. Remote sensing for the oil in ice Joint Industry Program 2007-2009

    International Nuclear Information System (INIS)

    Dickins, D.; Andersen, J.H.S; Brandvik, P.J.; Singsaas, I.; Buvik, T.; Bradford, J.; Hall, R.; Babiker, M.; Kloster, K.; Sandven, S.

    2009-01-01

    The challenge of detecting, mapping and tracking oil spills on ice were discussed with particular reference to the importance of spill detection and mapping for Arctic oil spills, where the oil can be hidden from view under snow and ice during periods of almost total darkness. The remote sensing project (P5) with in the Oil-in-Ice Joint Industry Program aimed to establish whether off-the-shelf technologies and sensors could detect oil in the presence of ice in particular scenarios. The specific goals were to evaluate the limitations and capabilities of currently operational remote sensors for spill surveillance in ice regimes encountered during the 2008 and 2009 field experiments and to draw conclusions regarding which sensors are most likely to be effective in a variety of oil and ice situations. The project focused on proven, commercially available systems and technologies. These included airborne sensors such as Ultra-violet/Infrared ( UV/IR ), forward looking infrared (FLIR) and synthetic aperture radar/side-looking airborne radars (SAR/SLAR); all weather satellite systems involving SAR; dogs for surface oil detection; and ground penetrating radar (GPR) for low level airborne oil on ice detection. The key finding was that flexible combinations of sensors operating from a variety of platforms are needed to cover a range of oil in ice scenarios. The most effective solution to detect oil patches during periods of darkness or fog was to deploy closely spaced global positioning system (GPS) tracking buoys to follow the ice and the oil. 34 refs., 1 tab., 17 figs.

  4. Remote sensing for the oil in ice Joint Industry Program 2007-2009

    Energy Technology Data Exchange (ETDEWEB)

    Dickins, D. [DF Dickins Associates LLC, La Jolla, CA (United States); Andersen, J.H.S [Norconsult, Horten (Norway); Brandvik, P.J.; Singsaas, I. [SINTEF Materials and Chemistry, Trondheim (Norway); Buvik, T. [Trondheim Dog Training Centre, Trondheim (Norway); Bradford, J. [Boise State Univ., Boise, ID (United States); Hall, R. [Kongsberg Satellite Services, Tromso (Norway); Babiker, M.; Kloster, K.; Sandven, S. [Nansen Environmental and Remote Sensing Center, Bergen (Norway)

    2009-07-01

    The challenge of detecting, mapping and tracking oil spills on ice were discussed with particular reference to the importance of spill detection and mapping for Arctic oil spills, where the oil can be hidden from view under snow and ice during periods of almost total darkness. The remote sensing project (P5) with in the Oil-in-Ice Joint Industry Program aimed to establish whether off-the-shelf technologies and sensors could detect oil in the presence of ice in particular scenarios. The specific goals were to evaluate the limitations and capabilities of currently operational remote sensors for spill surveillance in ice regimes encountered during the 2008 and 2009 field experiments and to draw conclusions regarding which sensors are most likely to be effective in a variety of oil and ice situations. The project focused on proven, commercially available systems and technologies. These included airborne sensors such as Ultra-violet/Infrared ( UV/IR ), forward looking infrared (FLIR) and synthetic aperture radar/side-looking airborne radars (SAR/SLAR); all weather satellite systems involving SAR; dogs for surface oil detection; and ground penetrating radar (GPR) for low level airborne oil on ice detection. The key finding was that flexible combinations of sensors operating from a variety of platforms are needed to cover a range of oil in ice scenarios. The most effective solution to detect oil patches during periods of darkness or fog was to deploy closely spaced global positioning system (GPS) tracking buoys to follow the ice and the oil. 34 refs., 1 tab., 17 figs.

  5. Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia

    Science.gov (United States)

    Ellinghaus, E; Stanulla, M; Richter, G; Ellinghaus, D; te Kronnie, G; Cario, G; Cazzaniga, G; Horstmann, M; Panzer Grümayer, R; Cavé, H; Trka, J; Cinek, O; Teigler-Schlegel, A; ElSharawy, A; Häsler, R; Nebel, A; Meissner, B; Bartram, T; Lescai, F; Franceschi, C; Giordan, M; Nürnberg, P; Heinzow, B; Zimmermann, M; Schreiber, S; Schrappe, M; Franke, A

    2012-01-01

    Acute lymphoblastic leukemia (ALL) is a malignant disease of the white blood cells. The etiology of ALL is believed to be multifactorial and likely to involve an interplay of environmental and genetic variables. We performed a genome-wide association study of 355 750 single-nucleotide polymorphisms (SNPs) in 474 controls and 419 childhood ALL cases characterized by a t(12;21)(p13;q22) — the most common chromosomal translocation observed in childhood ALL — which leads to an ETV6–RUNX1 gene fusion. The eight most strongly associated SNPs were followed-up in 951 ETV6-RUNX1-positive cases and 3061 controls from Germany/Austria and Italy, respectively. We identified a novel, genome-wide significant risk locus at 3q28 (TP63, rs17505102, PCMH=8.94 × 10−9, OR=0.65). The separate analysis of the combined German/Austrian sample only, revealed additional genome-wide significant associations at 11q11 (OR8U8, rs1945213, P=9.14 × 10−11, OR=0.69) and 8p21.3 (near INTS10, rs920590, P=6.12 × 10−9, OR=1.36). These associations and another association at 11p11.2 (PTPRJ, rs3942852, P=4.95 × 10−7, OR=0.72) remained significant in the German/Austrian replication panel after correction for multiple testing. Our findings demonstrate that germline genetic variation can specifically contribute to the risk of ETV6–RUNX1-positive childhood ALL. The identification of TP63 and PTPRJ as susceptibility genes emphasize the role of the TP53 gene family and the importance of proteins regulating cellular processes in connection with tumorigenesis. PMID:22076464

  6. An Approximation Solution to Refinery Crude Oil Scheduling Problem with Demand Uncertainty Using Joint Constrained Programming

    OpenAIRE

    Duan, Qianqian; Yang, Genke; Xu, Guanglin; Pan, Changchun

    2014-01-01

    This paper is devoted to develop an approximation method for scheduling refinery crude oil operations by taking into consideration the demand uncertainty. In the stochastic model the demand uncertainty is modeled as random variables which follow a joint multivariate distribution with a specific correlation structure. Compared to deterministic models in existing works, the stochastic model can be more practical for optimizing crude oil operations. Using joint chance constraints, the demand unc...

  7. Evaluation of the 1997 Joint National Conference, Women in Engineering Program Advocates Network (WEPAN) and National Association of Minority Engineering Program Administrators (NAMEPA)

    Energy Technology Data Exchange (ETDEWEB)

    Brainard, Suzanne G.

    1997-07-01

    The primary goal of the 1997 Joint National Conference was to unite NAMEPA and WEPAN in a unique collaborative effort to further the cause of increasing the participation of women and minorities in science and engineering. The specific objectives were to: (1) conduct technical and programmatic seminars for institutions desiring to initiate, replicate, or expand women and minorities in engineering program; (2) provide assistance in fundraising and grant writing; (3) profile women in engineering programs of excellence; (4) sponsor inspiring knowledgeable and motivational keynote speakers; and (5) offer a series of workshops focused on a multitude of topics.

  8. Telelegend Leo Karpin : ETV uus juhtkond teeb vaid lammutustööd / Leo Karpin ; interv. Verni Leivak

    Index Scriptorium Estoniae

    Karpin, Leo, 1946-2014

    2004-01-01

    Pea 40 aastat Eesti Televisioonis töötanud telerežissöör oma teletöölt lahkumise põhjustest. Lisaks kommentaar "ETV juhatuse esimees Ilmar Raag, miks tunnustatud telemees Leo Karpin ametist vabastati?"

  9. An approximation solution to refinery crude oil scheduling problem with demand uncertainty using joint constrained programming.

    Science.gov (United States)

    Duan, Qianqian; Yang, Genke; Xu, Guanglin; Pan, Changchun

    2014-01-01

    This paper is devoted to develop an approximation method for scheduling refinery crude oil operations by taking into consideration the demand uncertainty. In the stochastic model the demand uncertainty is modeled as random variables which follow a joint multivariate distribution with a specific correlation structure. Compared to deterministic models in existing works, the stochastic model can be more practical for optimizing crude oil operations. Using joint chance constraints, the demand uncertainty is treated by specifying proximity level on the satisfaction of product demands. However, the joint chance constraints usually hold strong nonlinearity and consequently, it is still hard to handle it directly. In this paper, an approximation method combines a relax-and-tight technique to approximately transform the joint chance constraints to a serial of parameterized linear constraints so that the complicated problem can be attacked iteratively. The basic idea behind this approach is to approximate, as much as possible, nonlinear constraints by a lot of easily handled linear constraints which will lead to a well balance between the problem complexity and tractability. Case studies are conducted to demonstrate the proposed methods. Results show that the operation cost can be reduced effectively compared with the case without considering the demand correlation.

  10. An Approximation Solution to Refinery Crude Oil Scheduling Problem with Demand Uncertainty Using Joint Constrained Programming

    Directory of Open Access Journals (Sweden)

    Qianqian Duan

    2014-01-01

    Full Text Available This paper is devoted to develop an approximation method for scheduling refinery crude oil operations by taking into consideration the demand uncertainty. In the stochastic model the demand uncertainty is modeled as random variables which follow a joint multivariate distribution with a specific correlation structure. Compared to deterministic models in existing works, the stochastic model can be more practical for optimizing crude oil operations. Using joint chance constraints, the demand uncertainty is treated by specifying proximity level on the satisfaction of product demands. However, the joint chance constraints usually hold strong nonlinearity and consequently, it is still hard to handle it directly. In this paper, an approximation method combines a relax-and-tight technique to approximately transform the joint chance constraints to a serial of parameterized linear constraints so that the complicated problem can be attacked iteratively. The basic idea behind this approach is to approximate, as much as possible, nonlinear constraints by a lot of easily handled linear constraints which will lead to a well balance between the problem complexity and tractability. Case studies are conducted to demonstrate the proposed methods. Results show that the operation cost can be reduced effectively compared with the case without considering the demand correlation.

  11. Joint Exercise Program: DOD Needs to Take Steps to Improve the Quality of Funding Data

    Science.gov (United States)

    2017-02-01

    need to do their due diligence in uploading supporting documentation in order to ensure proper accountability of Combatant Commanders Exercise...Event Life Cycle5 methodology captured and reviewed in JTIMS. Task Performance Observations—which identify whether the training audience achieved the...5The Joint Event Life Cycle comprises the design, planning, preparation, execution

  12. Mission and work program of the Joint Committee on Structural Safety

    NARCIS (Netherlands)

    Vrouwenvelder, A.C.W.M.; Faber, M.H.; Chryssanthopoulos, M.

    2003-01-01

    The Joint Committee on Structural Safety (JCSS for short) is concerned with fundamental and pre-normative research in the field of Structural Reliability and Risk Assessment, and is directly and indirectly involved in the development of ISO-standards and Eurocodes. The JCSS acts on behalf of five

  13. 76 FR 10598 - Medicare and Medicaid Programs; Approval of the Joint Commission for Deeming Authority for...

    Science.gov (United States)

    2011-02-25

    ... corporal punishment. To meet the requirements at Sec. 482.24(b)(2), the Joint Commission revised its... include both short-term and long-range patient goals. To meet the requirements at Sec. 482.61(c)(1)(iv.... B. Term of Approval Based on the review and observations described in section III. of this final...

  14. 76 FR 59134 - Medicare and Medicaid Programs; Approval of the Joint Commission's Continued Deeming Authority...

    Science.gov (United States)

    2011-09-23

    ... address the requirement that physician assistants, nurse practitioners, or clinical nurse specialists.... SUMMARY: This notice announces our decision to approve the Joint Commission for continued recognition as a... complaints against accredited facilities. ++ Survey review and decision-making process for accreditation. A...

  15. A Model for a Single Unmanned Aircraft Systems (UAS) Program Office Managing Joint ISR Capabilities

    Science.gov (United States)

    2017-10-01

    managing the efforts of medium and high altitude UAS assets from a Joint perspective while employing agile principles versus the duplicative efforts... managed using agile principles , could provide greater capability to the warfighter. Consolidation cost efficiencies became an independent variable...ensure quality and value are delivered. Senior leadership buy in is needed, along with an understanding of agile principles and management style that

  16. Impact of the Joint Task Force on Undergraduate Physics Programs for Innovation and Entrepreneurship Education in Physics

    Science.gov (United States)

    Arion, Douglas

    The Joint Task Force on Undergraduate Physics Programs has worked diligently to develop recommendations for what physics programs could and should be doing to prepare graduates for 21st century careers. While the `traditional' physics curriculum has served for many years, the demands of the new workforce, and the recognition that only a few percent of physics students actually become faculty - the vast majority entering the workforce and applying their skills to a very diverse range of problems, projects, and products - implies that a review of the education undergraduates receives is in order. The outcomes of this study point to the need to provide greater connection between the education process and the actual skills, knowledge, and abilities that the workplace demands. This presentation will summarize these considerations, and show how entrepreneurship and innovation programs and curricula are a particularly effective means of bringing these elements to physics students.

  17. 95. German Roentgen congress and 7. joint congress of the DRG and OeRG. Program with abstracts

    International Nuclear Information System (INIS)

    Diederich, Stefan; Lammer, Johannes

    2014-01-01

    The volume contains the program and the abstracts of the 95th German Roentgen congress and the 7th joint congress of the DRG and OeRG. The radiological focal points of the congress were thorax radiology (pneumology: lung fibrosis, emphysema); oncological radiology: skeletal carcinoma, lung carcinoma, kidneys, lung metastases, primary liver carcinoma, liver metastases. Further topics included radiology in hospitals and medical centers, tele-radiology, ambulant health care, legal issues, financial accounting and management issues. Several courses an specific radiological issues and radiological techniques were offered, including radiation protection and legal aspects.

  18. A joint program for seismographic station operations in the Republic of Kazakstan

    International Nuclear Information System (INIS)

    Kim, W.Y.; Belyashova, N.N.; Richards, P.G.

    1998-01-01

    In this paper there are examples of seismic signals recorded at the stations operated jointly by the Kazakhstan National Nuclear Centre and Lamont-Doherty Earth Observatory of Columbia University. Also the way the stations can be used to interpret the natural (earthquake) and and anthropogenic (explosion) sources from which the signals originated is shown. Examples include nuclear explosions carried out by China, India and Pakistan in recent years and months

  19. DOD Joint Bases: Implementation Challenges Demonstrate Need to Reevaluate the Program

    Science.gov (United States)

    2014-09-01

    28. Military and family support 8. Emergency management 29. Military personnel services 9. Environmental 30. Morale, welfare , and recreation...military and civilian personnel to provide a specific installation-support function, whereas the Army may have outsourced the provision of the same...facility-sustainment function because of how the Army and Air Force provided installation support prior to joint basing. The Army outsourced delivery of

  20. Near-term electric test vehicle ETV-2. Phase II. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1981-04-01

    A unique battery-powered passenger vehicle has been developed that provides a significant improvement over conventional electric vehicle performance, particularly during stop-and-go driving. The vehicle is unique in two major respects: (1) the power system incorporates a flywheel that stores energy during regenerative braking and makes possible the acceleration capability needed to keep up with traffic without reducing range to unacceptable values; and (2) lightweight plastic materials are used for the vehicle unibody to minimize weight and increase range. These features were analyzed and demonstrated in an electric test vehicle, ETV-2. Characteristics of this vehicle are summarized. Information is presented on: vehicle design, fabrication, safety testing, and performance testing; power system design and operation; flywheel; battery pack performance; and controls and electronic equipment. (LCL)

  1. Joint Assessment of Renewable Energy and Water Desalination Research Center (REWDC) Program Capabilities and Facilities In Radioactive Waste Management

    International Nuclear Information System (INIS)

    Bissani, M; Fischer, R; Kidd, S; Merrigan, J

    2006-01-01

    The primary goal of this visit was to perform a joint assessment of the Renewable Energy and Water Desalination Center's (REWDC) program in radioactive waste management. The visit represented the fourth technical and scientific interaction with Libya under the DOE/NNSA Sister Laboratory Arrangement. Specific topics addressed during the visit focused on Action Sheet P-05-5, ''Radioactive Waste Management''. The Team, comprised of Mo Bissani (Team Lead), Robert Fischer, Scott Kidd, and Jim Merrigan, consulted with REWDC management and staff. The team collected information, discussed particulars of the technical collaboration and toured the Tajura facility. The tour included the waste treatment facility, waste storage/disposal facility, research reactor facility, hot cells and analytical labs. The assessment team conducted the first phase of Task A for Action Sheet 5, which involved a joint assessment of the Radioactive Waste Management Program. The assessment included review of the facilities dedicated to the management of radioactive waste at the Tourja site, the waste management practices, proposed projects for the facility and potential impacts on waste generation and management

  2. Medicare Program; Comprehensive Care for Joint Replacement Payment Model for Acute Care Hospitals Furnishing Lower Extremity Joint Replacement Services. Final rule.

    Science.gov (United States)

    2015-11-24

    This final rule implements a new Medicare Part A and B payment model under section 1115A of the Social Security Act, called the Comprehensive Care for Joint Replacement (CJR) model, in which acute care hospitals in certain selected geographic areas will receive retrospective bundled payments for episodes of care for lower extremity joint replacement (LEJR) or reattachment of a lower extremity. All related care within 90 days of hospital discharge from the joint replacement procedure will be included in the episode of care. We believe this model will further our goals in improving the efficiency and quality of care for Medicare beneficiaries with these common medical procedures.

  3. Epidermal growth factor receptor signaling promotes metastatic prostate cancer through microRNA-96-mediated downregulation of the tumor suppressor ETV6.

    Science.gov (United States)

    Tsai, Yuan-Chin; Chen, Wei-Yu; Siu, Man Kit; Tsai, Hong-Yuan; Yin, Juan Juan; Huang, Jiaoti; Liu, Yen-Nien

    2017-01-01

    It has been suggested that ETV6 serves as a tumor suppressor; however, its molecular regulation and cellular functions remain unclear. We used prostate cancer as a model system and demonstrated a molecular mechanism in which ETV6 can be regulated by epidermal growth factor receptor (EGFR) signaling through microRNA-96 (miR-96)-mediated downregulation. In addition, EGFR acts as a transcriptional coactivator that binds to the promoter of primary miR-96 and transcriptionally regulates miR-96 levels. We analyzed two sets of clinical prostate cancer samples, confirmed association patterns that were consistent with the EGFR-miR-96-ETV6 signaling model and demonstrated that the reduced ETV6 levels were associated with malignant prostate cancer. Based on results derived from multiple approaches, we identified the biological functions of ETV6 as a tumor suppressor that inhibits proliferation and metastasis in prostate cancer. We present a molecular mechanism in which EGFR activation leads to the induction of miR-96 expression and suppression of ETV6, which contributes to prostate cancer progression. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  4. 2014-2015 Partnership accomplishments report on joint activities: National Gap Analysis Program and LANDFIRE

    Science.gov (United States)

    Davidson, Anne; McKerrow, Alexa; Long, Don; Earnhardt, Todd

    2015-01-01

    The intended target audience for this document initially is management and project technical specialist and scientists involved in the Gap Analysis Program (GAP) and the Landscape Fire and Resource Management Planning Tools - (LANDFIRE) program to help communicate coordination activities to all involved parties. This document is also intended to give background information in other parts of the USGS and beyond, although some details given are relatively oriented to management of the respective programs. Because the Gap Analysis Program (GAP) and the Landscape Fire and Resource Management Planning Tools - LANDFIRE programs both rely on characterizations of land cover using similar scales and resolutions, the programs have been coordinating their work to improve scientific consistency and efficiency of production. Initial discussions and informal sharing of ideas and work began in 2008. Although this collaboration was fruitful, there was no formal process for reporting results, plans, or outstanding issues, nor was there any formally-defined coordinated management team that spanned the two programs. In 2012, leadership from the two programs agreed to strengthen the coordination of their respective work efforts. In 2013 the GAP and LANDFIRE programs developed an umbrella plan of objectives and components related to three mutual focus areas for the GAP and LANDFIRE collaboration for the years 2013 and 2014 (GAP/LANDFIRE 2013). The evolution of this partnership resulted in the drafting of an inter-program Memorandum of Understanding (MOU) in 2014. This MOU identified three coordination topics relevant to the two programs participating at this point in the MOU history: Vegetation mappingDisturbance classesFormal quality assessment

  5. Readers of the Round Table: The 1998 Joint Kentucky - Arizona Reading Program.

    Science.gov (United States)

    Kentucky State Dept. for Libraries and Archives, Frankfort.

    Intended to encourage children of all ages to read over the summer, this manual presents library-based programs, crafts, displays, and events with a medieval theme. The chapters of the manual are: (1) Introductory Materials; (2) Goals, Objectives and Evaluation; (3) Getting Started; (4) Common Program Structures; (5) Planning Timeline; (6)…

  6. Contingency planning for oil spill response: A program of joint IMO/oil industry regional seminars

    International Nuclear Information System (INIS)

    Bavister, R.; Wonham, J.

    1993-01-01

    Cooperative efforts between the oil industry and governments at the national and local levels have resulted in a series of reports for both technical and general audiences on subjects relating to oil spills, as well as an ongoing series of government/industry regional seminars for senior executives. The seminars emphasize the crucial importance of joint government/industry attention to contingency planning. These activities, which are continuing, are organized under the auspices of an International Petroleum Industry Environmental Conservation Association working group, and the International Maritime Organization. Feedback is solicited from seminar participants for use in planning further seminars and to give the IMO a clear picture of follow up activities that have resulted from the seminars

  7. Business Case Analysis of the Joint Strike Fighter's Alternate Engine Program

    National Research Council Canada - National Science Library

    Shick, BethAnn

    2007-01-01

    .... The JSF will serve the Air Force, Navy and Marine Corps, as well as many of our key international allies In 1998, the DoD initiated the JSF alternate engine program in an effort to achieve cost...

  8. 75 FR 45694 - ITS Joint Program Office; IntelliDriveSM

    Science.gov (United States)

    2010-08-03

    ... professionals from the public and private sectors. The meeting is open to the public at no charge (public... the IntelliDrive research program and to obtain stakeholder input on user needs for the definition of...

  9. F-35 Joint Strike Fighter (JSF) Program: Background and Issues for Congress

    Science.gov (United States)

    2011-04-26

    bulkheads on the F-22.”28 Third, the driveshaft, lift-fan clutch, and actuator for the F-35B’s roll-post nozzles will be redesigned following...levels of participation in the program. International partners are also assisting with Initial Operational Test and Evaluation ( IOT &E), a subset of...Week/Ares blog, March 15, 2010. 59 Currently, the UK, Italy, and the Netherlands have agreed to participate in the IOT &E program. UK, the senior F

  10. A Multidimensional Analysis of the Joint Strike Fighter (JSF) Acquisition Program from the Perspective of Turkey

    Science.gov (United States)

    2016-12-01

    the largest and the most expensive development and acquisition program in history, with eight cost-sharing participant countries , which are the United...JSF) ACQUISITION PROGRAM FROM THE PERSPECTIVE OF TURKEY December 2016 By: Asım Furkan Demir Advisors: Nicholas Dew Mie-Sophia...VA 22202-4302, and to the Office of Management and Budget, Paperwork Reduction Project (0704-0188) Washington DC 20503. 1. AGENCY USE ONLY (Leave

  11. The juxtamembrane domain in ETV6/FLT3 is critical for PIM-1 up-regulation and cell proliferation

    International Nuclear Information System (INIS)

    Vu, Hoang Anh; Xinh, Phan Thi; Kano, Yasuhiko; Tokunaga, Katsushi; Sato, Yuko

    2009-01-01

    We recently reported that the ETV6/FLT3 fusion protein conferred interleukin-3-independent growth on Ba/F3 cells. The present study has been conducted to assess role of the juxtamembrane domain of FLT3 for signal transduction and cell transformation. The wild-type ETV6/FLT3 fusion protein in transfected cells was a constitutively activated tyrosine kinase that led to up-regulation of PIM-1 and activations of STAT5, AKT, and MAPK. Deletion of the juxtamembrane domain abrogated interleukin-3-independent growth of the transfected cells and PIM-1 up-regulation, whereas it retained compatible levels of phosphorylations of STAT5, AKT, and MAPK. Further deletion of N-terminal region of the tyrosine kinase I domain of FLT3 completely abolished these phosphorylations. Our data indicate that the juxtamembrane domain of FLT3 in ETV6/FLT3 fusion protein is critical for cell proliferation and PIM-1 up-regulation that might be independent of a requirement for signaling through STAT5, MAPK, and AKT pathways.

  12. E2F1-Mediated Induction of NFYB Attenuates Apoptosis via Joint Regulation of a Pro-Survival Transcriptional Program.

    Directory of Open Access Journals (Sweden)

    Xiaolei Jiang

    Full Text Available The E2F1 transcription factor regulates cell proliferation and apoptosis through the control of a considerable variety of target genes. Previous work has detailed the role of other transcription factors in mediating the specificity of E2F function. Here we identify the NF-YB transcription factor as a novel direct E2F1 target. Genome-wide expression analysis of the effects of NFYB knockdown on E2F1-mediated transcription identified a large group of genes that are co-regulated by E2F1 and NFYB. We also provide evidence that knockdown of NFYB enhances E2F1-induced apoptosis, suggesting a pro-survival function of the NFYB/E2F1 joint transcriptional program. Bioinformatic analysis suggests that deregulation of these NFY-dependent E2F1 target genes might play a role in sarcomagenesis as well as drug resistance.

  13. The Joint Fire Science Program Fire Exchange Network: Facilitating Knowledge Exchange About Wildland Fire Science Across the U.S.

    Science.gov (United States)

    York, A.; Blocksome, C.; Cheng, T.; Creighton, J.; Edwards, G.; Frederick, S.; Giardina, C. P.; Goebel, P. C.; Gucker, C.; Kobziar, L.; Lane, E.; Leis, S.; Long, A.; Maier, C.; Marschall, J.; McGowan-Stinski, J.; Mohr, H.; MontBlanc, E.; Pellant, M.; Pickett, E.; Seesholtz, D.; Skowronski, N.; Stambaugh, M. C.; Stephens, S.; Thode, A.; Trainor, S. F.; Waldrop, T.; Wolfson, B.; Wright, V.; Zedler, P.

    2014-12-01

    The Joint Fire Science Program's (JFSP) Fire Exchange Network is actively working to accelerate the awareness, understanding, and adoption of wildland fire science information by federal, tribal, state, local, and private stakeholders within ecologically similar regions. Our network of 15 regional exchanges provides timely, accurate, and regionally relevant science-based information to assist with fire management challenges. Regional activities, through which we engage fire and resource managers, scientists, and private landowners, include online newsletters and announcements, social media, regionally focused web-based clearinghouses of relevant science, field trips and demonstration sites, workshops and conferences, webinars and online training, and syntheses and fact sheets. Exchanges also help investigators design research that is relevant to regional management needs and assist with technology transfer to management audiences. This poster provides an introduction to and map of the regional exchanges.

  14. FLANGE: a computer program for the analysis of flanged joints with ring-type gaskets

    International Nuclear Information System (INIS)

    Rodabaugh, E.C.; O'Hara, F.M. Jr.; Moore, S.E.

    1976-01-01

    The computer program FLANGE was written to calculate not only the stresses due to moment loads on the flange ring but also stresses due to internal pressure; stresses due to a temperature difference between the hub and ring; and stresses due to the variations in bolt load that result from pressure, hub-ring temperature gradient, and/or bolt-ring temperature difference. The program FLANGE is applicable to tapered-hub, straight, and blind flanges. The analysis method is based on the differential equations for thin plates and shells. The stresses due to moment loading calculated by the two methods are essentially identical for identical boundary conditions. A description of the general model of flanges used in the theoretical development of the computer code is provided. The actual mathematical expressions for calculating stresses and displacements due to moment and pressure loads are derived. Example calculations, listings, and flowcharts of the program and its subroutines are included as appendices

  15. Joint FAM/Line Management Assessment Report on LLNL Machine Guarding Safety Program

    Energy Technology Data Exchange (ETDEWEB)

    Armstrong, J. J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-07-19

    The LLNL Safety Program for Machine Guarding is implemented to comply with requirements in the ES&H Manual Document 11.2, "Hazards-General and Miscellaneous," Section 13 Machine Guarding (Rev 18, issued Dec. 15, 2015). The primary goal of this LLNL Safety Program is to ensure that LLNL operations involving machine guarding are managed so that workers, equipment and government property are adequately protected. This means that all such operations are planned and approved using the Integrated Safety Management System to provide the most cost effective and safest means available to support the LLNL mission.

  16. Implementing joint tuberculosis projects in Somaliland and Sweden for mutual strengthening of programs and research

    Directory of Open Access Journals (Sweden)

    Abdi Yassin

    2015-01-01

    Discussion and conclusions: Herein this study presents a planned TB project aiming at cooperation between healthcare staff from a low- and a high-endemic country. For such a project, several baseline data are required, e.g., the pattern of resistance of MTB and the treatment outcome in Somaliland, as well as among immigrants in Sweden. The social circumstances for any patient with TB, whether in Somaliland or Sweden, during disease and when recovered is a main issue for health from a holistic perspective. Further, the nutritional status is not satisfactory for TB patients in either country, and a dietary intervention may be of importance in both countries. Baseline data according to the above are necessary for assessment of the interventions and are part of ongoing pre-studies. For the Swedish party the exchange of clinical knowledge is beneficial since TB is rare in Sweden and access to TB research and clinical implantation of new methods will be facilitated and possible through the joint project. Ultimately, an expanded project could curb TB at the source and decrease TB in both countries.

  17. DOE-NE Light Water Reactor Sustainability Program and EPRI Long-Term Operations Program. Joint Research and Development Plan

    International Nuclear Information System (INIS)

    Williams, Don

    2014-01-01

    Nuclear power has contributed almost 20% of the total amount of electricity generated in the United States over the past two decades. High capacity factors and low operating costs make nuclear power plants (NPPs) some of the most economical power generators available. Further, nuclear power remains the single largest contributor (nearly 70%) of non-greenhouse gas-emitting electric power generation in the United States. Even when major refurbishments are performed to extend operating life, these plants continue to represent cost-effective, low-carbon assets to the nation's electrical generation capability. By the end of 2014, about one-third of the existing domestic fleet will have passed their 40th anniversary of power operations, and about one-half of the fleet will reach the same 40-year mark within this decade. Recognizing the challenges associated with pursuing extended service life of commercial nuclear power plants, the U.S. Department of Energy's (DOE) Office of Nuclear Energy [NE] and the Electric Power Research Institute (EPRI) have established separate but complementary research and development programs (DOE-NE's Light Water Reactor Sustainability [LWRS] Program and EPRI's Long-Term Operations [LTO] Program) to address these challenges. To ensure that a proper linkage is maintained between the programs, DOE-NE and EPRI executed a memorandum of understanding in late 2010 to @@@establish guiding principles under which research activities (between LWRS and LTO) could be coordinated to the benefit of both parties.@@@ This document represents the third annual revision to the initial version (March 2011) of the plan as called for in the memorandum of understanding.

  18. DOE-NE Light Water Reactor Sustainability Program and EPRI Long-Term Operations Program. Joint Research and Development Plan

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Don

    2014-04-01

    Nuclear power has contributed almost 20% of the total amount of electricity generated in the United States over the past two decades. High capacity factors and low operating costs make nuclear power plants (NPPs) some of the most economical power generators available. Further, nuclear power remains the single largest contributor (nearly 70%) of non-greenhouse gas-emitting electric power generation in the United States. Even when major refurbishments are performed to extend operating life, these plants continue to represent cost-effective, low-carbon assets to the nation’s electrical generation capability. By the end of 2014, about one-third of the existing domestic fleet will have passed their 40th anniversary of power operations, and about one-half of the fleet will reach the same 40-year mark within this decade. Recognizing the challenges associated with pursuing extended service life of commercial nuclear power plants, the U.S. Department of Energy’s (DOE) Office of Nuclear Energy (NE) and the Electric Power Research Institute (EPRI) have established separate but complementary research and development programs (DOE-NE’s Light Water Reactor Sustainability [LWRS] Program and EPRI’s Long-Term Operations [LTO] Program) to address these challenges. To ensure that a proper linkage is maintained between the programs, DOE-NE and EPRI executed a memorandum of understanding in late 2010 to “establish guiding principles under which research activities (between LWRS and LTO) could be coordinated to the benefit of both parties.” This document represents the third annual revision to the initial version (March 2011) of the plan as called for in the memorandum of understanding.

  19. [Environmental Hazards Assessment Program annual report, June 1992--June 1993]. South Carolina ETV Socratic Dialog II

    Energy Technology Data Exchange (ETDEWEB)

    1993-06-01

    This report contains the script from a videotaped dialogue concerning a hypothetical hazardous waste/community health risk scenario presented as a Round Table Forum. Various issues are explored, ranging from the scientific and technical aspects of environmental studies and remedial action, to public information and community involvement, to the economic impact on local communities. The roles of the media, local government and federal and state agencies are examined as well as sources for funding. In an attempt to gauge audience response and reaction, evaluation cards were distributed, and the comments and recommendations are included here.

  20. The Joint Program Dilemma: Analyzing the Pervasive Role that Social Dilemmas Play in Undermining Acquisition Success

    Science.gov (United States)

    2013-04-01

    acquisition programs may substantially exceed budget, overrun schedule, deliver inadequate quality, and ultimately even fail ( Frangos , 1998; Madachy, 2008...Society. Fehr, E., & Gachter, S. (2002, January). Altruistic punishment in humans. Nature, 415, 137–140. Frangos , S. A. (1998). Motivated humans for

  1. 76 FR 34286 - ITS Joint Program Office; Webinar on Connected Vehicle Infrastructure Deployment Analysis Report...

    Science.gov (United States)

    2011-06-13

    ... communications devices to improve safety, mobility, and environmental sustainability. The program is the major research initiative of the ITS JPO, which is currently working with the eight major automotive companies to... safety, mobility and sustainability. There is also connected vehicle-related research in the areas of...

  2. Joint Service Chemical and Biological Defense Program: FY 06-07 Overview

    Science.gov (United States)

    2006-01-01

    Performers Molecular model of human plasma-derived butyryl Electronmicrograph of bacillus spores adhering to cell membrane processes 38866_BATT_TX 11...agents, and radioactive fallout. CPS is integrated with the ship’s Heating, Ventilation, and Air-Conditioning ( HVAC ) systems and provides filtered air...molecules for intervention against protein NTA. • Identify and evaluate effectiveness of spore germination inhibitors. • Expand drug discovery program

  3. RNF4 interacts with multiSUMOylated ETV4 [version 2; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Elisa Aguilar-Martinez

    2017-02-01

    Full Text Available Protein SUMOylation represents an important regulatory event that changes the activities of numerous proteins. Recent evidence demonstrates that polySUMO chains can act as a trigger to direct the ubiquitin ligase RNF4 to substrates to cause their turnover through the ubiquitin pathway. RNF4 uses multiple SUMO interaction motifs (SIMs to bind to these chains. However, in addition to polySUMO chains, a multimeric binding surface created by the simultaneous SUMOylation of multiple residues on a protein or complex could also provide a platform for the recruitment of multi-SIM proteins like RNF4. Here we demonstrate that multiSUMOylated ETV4 can bind to RNF4 and that a unique combination of SIMs is required for RNF4 to interact with this multiSUMOylated platform. Thus RNF4 can bind to proteins that are either polySUMOylated through a single site or multiSUMOylated on several sites and raises the possibility that such multiSIM-multiSUMO interactions might be more widespread.

  4. Joint pricing and production management: a geometric programming approach with consideration of cubic production cost function

    Science.gov (United States)

    Sadjadi, Seyed Jafar; Hamidi Hesarsorkh, Aghil; Mohammadi, Mehdi; Bonyadi Naeini, Ali

    2015-06-01

    Coordination and harmony between different departments of a company can be an important factor in achieving competitive advantage if the company corrects alignment between strategies of different departments. This paper presents an integrated decision model based on recent advances of geometric programming technique. The demand of a product considers as a power function of factors such as product's price, marketing expenditures, and consumer service expenditures. Furthermore, production cost considers as a cubic power function of outputs. The model will be solved by recent advances in convex optimization tools. Finally, the solution procedure is illustrated by numerical example.

  5. Aircraft and ground vehicle friction correlation test results obtained under winter runway conditions during joint FAA/NASA Runway Friction Program

    Science.gov (United States)

    Yager, Thomas J.; Vogler, William A.; Baldasare, Paul

    1988-01-01

    Aircraft and ground vehicle friction data collected during the Joint FAA/NASA Runway Friction Program under winter runway conditions are discussed and test results are summarized. The relationship between the different ground vehicle friction measurements obtained on compacted snow- and ice-covered conditions is defined together with the correlation to aircraft tire friction performance under similar runway conditions.

  6. Joint Oil Analysis Program Spectrometer Standards SCP Science (Conostan) Qualification Report for D19-0, D3-100, and D12-XXX Series Standards

    Science.gov (United States)

    2015-05-20

    Joint Oil Analysis Program Spectrometer Standards SCP Science (Conostan) Qualification Report For D19-0, D3-100, and D12- XXX Series Standards NF...Candidate Type D19-0 ICP-AES Results ..................................................................... 4 Table V. Candidate Type D12- XXX ...Physical Property Results .................................................. 5 Table VI. Candidate Type D12- XXX Rotrode-AES Results

  7. CHANDA and ERINDA: Joint European programs for research on safety of nuclear facilities and waste reduction

    Energy Technology Data Exchange (ETDEWEB)

    Beyer, Roland; Hannaske, Roland; Koegler, Toni [Institut fuer Strahlenphysik, Helmholtz Zentrum DD-Rossendorf, 01328 Dresden (Germany); Institut fuer Kern- und Teilchenphysik, TU Dresden, 01069 Dresden (Germany); Grosse, Eckart [Institut fuer Kern- und Teilchenphysik, TU Dresden, 01069 Dresden (Germany); Junghans, Arnd R. [Institut fuer Strahlenphysik, Helmholtz Zentrum DD-Rossendorf, 01328 Dresden (Germany)

    2014-07-01

    In spite of the planned termination of the German nuclear power program neutron beam facilities in Germany can contribute considerably to research studies on the reduction of hazards due to nuclear waste. Transnational research programs support EU groups who want to carry out projects at the new tof set-up nELBE at HZDR, the calibrated n-flux at PTB and the FRANZ accelerator under construction at Frankfurt. Vice versa various facilities in the EU offer beams for transmutation and safety related studies with neutrons to German scientists under support by ERINDA (2011-2013) and CHANDA (2014-2017; solving challenges in nuclear data for the safety of European nuclear facilities). For work in that field scientific visits are also fostered to improve the exchange of experience between the partners (13 and in future about 35 from 18 countries). Plans for new projects as well as results obtained so far are discussed, and special emphasis is given to the present research performed at nELBE on neutron scattering and absorption.

  8. Status of the CNES-CEA joint program on space nuclear Brayton systems

    International Nuclear Information System (INIS)

    Carre, F.; Proust, E.; Chaudourne, S.; Keirle, P.; Tilliette, Z.; Vrillon, B.

    1989-01-01

    A cooperative program between the French Centre National d'Etudes Spatiales (CNES) and the Commissariat a l'Energie Atomique (CEA) was initiated in 1983, to investigate the possible development of 20 to 200 kWe space nuclear power systems to be launched by the next version of the European launcher, Ariane V. After completion in 1986 of preliminary conceptual studies of a reference 200 kWe turbo-electric power system, an additional 3 year study phase was decided, with the double objective of assessing the potential advantage of nuclear power systems versus solar photovoltaic or dynamic systems in the 20 kWe power range, and comparing various reactor candidate technologies and system options for 20 kWe space nuclear power systems, likely to meet the projected energy needs of future European space missions. A comprehensive program including conceptual design studies, operating transient analyses and technology base assessment, is currently applied to a few reference concepts of 20 kWe nuclear Brayton and thermoelectric systems, in order to establish sound technical and economical bases for selecting the design options and the development strategy of a first space nuclear power system in Europe

  9. Status of the CNES-CEA joint program on space nuclear Brayton systems

    International Nuclear Information System (INIS)

    Carre, F.; Proust, E.; Chaudourne, S.; Keirle, P.; Tilliette, Z.; Vrillon, B.

    1989-01-01

    A Cooperative program between the French Centre National d'Etudes Spatiales (CNES) and the Commissariat a l'Engergie Atomique (CEA) was initiated in 1983, to investigate the possible development of 20 to 200 kWe space nuclear power systems to be launched by the next version of the European launcher, Ariane V. After completion in 1986 of preliminary conceptual studies of a reference 200 kWe turboelectric power system, an additional 3 year study phase was decided, with the double objective of assessing the potential advantage of nuclear power systems versus solar photovoltaic or dynamic systems in the 20 kWe power range, and comparing various reactor candidate technologies and systems options for 20 kWe space nuclear power systems, likely to meet the projected energy needs of future European space missions. The results of this study are discussed by the authors

  10. From design to implementation--the Joint Asia Diabetes Evaluation (JADE) program: a descriptive report of an electronic web-based diabetes management program.

    Science.gov (United States)

    Ko, Gary T; So, Wing-Yee; Tong, Peter C; Le Coguiec, Francois; Kerr, Debborah; Lyubomirsky, Greg; Tamesis, Beaver; Wolthers, Troels; Nan, Jennifer; Chan, Juliana

    2010-05-13

    The Joint Asia Diabetes Evaluation (JADE) Program is a web-based program incorporating a comprehensive risk engine, care protocols, and clinical decision support to improve ambulatory diabetes care. The JADE Program uses information technology to facilitate healthcare professionals to create a diabetes registry and to deliver an evidence-based care and education protocol tailored to patients' risk profiles. With written informed consent from participating patients and care providers, all data are anonymized and stored in a databank to establish an Asian Diabetes Database for research and publication purpose. The JADE electronic portal (e-portal: http://www.jade-adf.org) is implemented as a Java application using the Apache web server, the mySQL database and the Cocoon framework. The JADE e-portal comprises a risk engine which predicts 5-year probability of major clinical events based on parameters collected during an annual comprehensive assessment. Based on this risk stratification, the JADE e-portal recommends a care protocol tailored to these risk levels with decision support triggered by various risk factors. Apart from establishing a registry for quality assurance and data tracking, the JADE e-portal also displays trends of risk factor control at each visit to promote doctor-patient dialogues and to empower both parties to make informed decisions. The JADE Program is a prototype using information technology to facilitate implementation of a comprehensive care model, as recommended by the International Diabetes Federation. It also enables health care teams to record, manage, track and analyze the clinical course and outcomes of people with diabetes.

  11. From design to implementation - The Joint Asia Diabetes Evaluation (JADE program: A descriptive report of an electronic web-based diabetes management program

    Directory of Open Access Journals (Sweden)

    Lyubomirsky Greg

    2010-05-01

    Full Text Available Abstract Background The Joint Asia Diabetes Evaluation (JADE Program is a web-based program incorporating a comprehensive risk engine, care protocols, and clinical decision support to improve ambulatory diabetes care. Methods The JADE Program uses information technology to facilitate healthcare professionals to create a diabetes registry and to deliver an evidence-based care and education protocol tailored to patients' risk profiles. With written informed consent from participating patients and care providers, all data are anonymized and stored in a databank to establish an Asian Diabetes Database for research and publication purpose. Results The JADE electronic portal (e-portal: http://www.jade-adf.org is implemented as a Java application using the Apache web server, the mySQL database and the Cocoon framework. The JADE e-portal comprises a risk engine which predicts 5-year probability of major clinical events based on parameters collected during an annual comprehensive assessment. Based on this risk stratification, the JADE e-portal recommends a care protocol tailored to these risk levels with decision support triggered by various risk factors. Apart from establishing a registry for quality assurance and data tracking, the JADE e-portal also displays trends of risk factor control at each visit to promote doctor-patient dialogues and to empower both parties to make informed decisions. Conclusions The JADE Program is a prototype using information technology to facilitate implementation of a comprehensive care model, as recommended by the International Diabetes Federation. It also enables health care teams to record, manage, track and analyze the clinical course and outcomes of people with diabetes.

  12. From design to implementation - The Joint Asia Diabetes Evaluation (JADE) program: A descriptive report of an electronic web-based diabetes management program

    Science.gov (United States)

    2010-01-01

    Background The Joint Asia Diabetes Evaluation (JADE) Program is a web-based program incorporating a comprehensive risk engine, care protocols, and clinical decision support to improve ambulatory diabetes care. Methods The JADE Program uses information technology to facilitate healthcare professionals to create a diabetes registry and to deliver an evidence-based care and education protocol tailored to patients' risk profiles. With written informed consent from participating patients and care providers, all data are anonymized and stored in a databank to establish an Asian Diabetes Database for research and publication purpose. Results The JADE electronic portal (e-portal: http://www.jade-adf.org) is implemented as a Java application using the Apache web server, the mySQL database and the Cocoon framework. The JADE e-portal comprises a risk engine which predicts 5-year probability of major clinical events based on parameters collected during an annual comprehensive assessment. Based on this risk stratification, the JADE e-portal recommends a care protocol tailored to these risk levels with decision support triggered by various risk factors. Apart from establishing a registry for quality assurance and data tracking, the JADE e-portal also displays trends of risk factor control at each visit to promote doctor-patient dialogues and to empower both parties to make informed decisions. Conclusions The JADE Program is a prototype using information technology to facilitate implementation of a comprehensive care model, as recommended by the International Diabetes Federation. It also enables health care teams to record, manage, track and analyze the clinical course and outcomes of people with diabetes. PMID:20465815

  13. Evaluation of the Program in Medical Education for the Urban Underserved (PRIME-US) at the UC Berkeley-UCSF Joint Medical Program (JMP): The First 4 Years.

    Science.gov (United States)

    Sokal-Gutierrez, Karen; Ivey, Susan L; Garcia, Roxanna M; Azzam, Amin

    2015-01-01

    Medical educators, clinicians, and health policy experts widely acknowledge the need to increase the diversity of our healthcare workforce and build our capacity to care for medically underserved populations and reduce health disparities. The Program in Medical Education for the Urban Underserved (PRIME-US) is part of a family of programs across the University of California (UC) medical schools aiming to recruit and train physicians to care for underserved populations, expand the healthcare workforce to serve diverse populations, and promote health equity. PRIME-US selects medical students from diverse backgrounds who are committed to caring for underserved populations and provides a 5-year curriculum including a summer orientation, a longitudinal seminar series with community engagement and leadership-development activities, preclerkship clinical immersion in an underserved setting, a master's degree, and a capstone rotation in the final year of medical school. This is a mixed-methods evaluation of the first 4 years of the PRIME-US at the UC Berkeley-UC San Francisco Joint Medical Program (JMP). From 2006 to 2010, focus groups were conducted each year with classes of JMP PRIME-US students, for a total of 11 focus groups; major themes were identified using content analysis. In addition, 4 yearly anonymous, online surveys of all JMP students, faculty and staff were conducted and analyzed. Most PRIME-US students came from socioeconomically disadvantaged backgrounds and ethnic backgrounds underrepresented in medicine, and all were committed to caring for underserved populations. The PRIME-US students experienced many program benefits including peer support, professional role models and mentorship, and curricular enrichment activities that developed their knowledge, skills, and sustained commitment to care for underserved populations. Non-PRIME students, faculty, and staff also benefited from participating in PRIME-sponsored seminars and community-based activities

  14. Dendritic Cells and Programmed Death-1 Blockade: A Joint Venture to Combat Cancer.

    Science.gov (United States)

    Versteven, Maarten; Van den Bergh, Johan M J; Marcq, Elly; Smits, Evelien L J; Van Tendeloo, Viggo F I; Hobo, Willemijn; Lion, Eva

    2018-01-01

    Two decades of clinical cancer research with dendritic cell (DC)-based vaccination have proved that this type of personalized medicine is safe and has the capacity to improve survival, but monotherapy is unlikely to cure the cancer. Designed to empower the patient's antitumor immunity, huge research efforts are set to improve the efficacy of next-generation DC vaccines and to find synergistic combinations with existing cancer therapies. Immune checkpoint approaches, aiming to breach immune suppression and evasion to reinforce antitumor immunity, have been a revelation in the immunotherapy field. Early success of therapeutic antibodies blocking the programmed death-1 (PD-1) pathway has sparked the development of novel inhibitors and combination therapies. Hence, merging immunoregulatory tumor-specific DC strategies with PD-1-targeted approaches is a promising path to explore. In this review, we focus on the role of PD-1-signaling in DC-mediated antitumor immunity. In the quest of exploiting the full potential of DC therapy, different strategies to leverage DC immunopotency by impeding PD-1-mediated immune regulation are discussed, including the most advanced research on targeted therapeutic antibodies, lessons learned from chemotherapy-induced immune activation, and more recent developments with soluble molecules and gene-silencing techniques. An overview of DC/PD-1 immunotherapy combinations that are currently under preclinical and clinical investigation substantiates the clinical potential of such combination strategies.

  15. JUPITER: Joint Universal Parameter IdenTification and Evaluation of Reliability - An Application Programming Interface (API) for Model Analysis

    Science.gov (United States)

    Banta, Edward R.; Poeter, Eileen P.; Doherty, John E.; Hill, Mary C.

    2006-01-01

    he Joint Universal Parameter IdenTification and Evaluation of Reliability Application Programming Interface (JUPITER API) improves the computer programming resources available to those developing applications (computer programs) for model analysis.The JUPITER API consists of eleven Fortran-90 modules that provide for encapsulation of data and operations on that data. Each module contains one or more entities: data, data types, subroutines, functions, and generic interfaces. The modules do not constitute computer programs themselves; instead, they are used to construct computer programs. Such computer programs are called applications of the API. The API provides common modeling operations for use by a variety of computer applications.The models being analyzed are referred to here as process models, and may, for example, represent the physics, chemistry, and(or) biology of a field or laboratory system. Process models commonly are constructed using published models such as MODFLOW (Harbaugh et al., 2000; Harbaugh, 2005), MT3DMS (Zheng and Wang, 1996), HSPF (Bicknell et al., 1997), PRMS (Leavesley and Stannard, 1995), and many others. The process model may be accessed by a JUPITER API application as an external program, or it may be implemented as a subroutine within a JUPITER API application . In either case, execution of the model takes place in a framework designed by the application programmer. This framework can be designed to take advantage of any parallel processing capabilities possessed by the process model, as well as the parallel-processing capabilities of the JUPITER API.Model analyses for which the JUPITER API could be useful include, for example: Compare model results to observed values to determine how well the model reproduces system processes and characteristics.Use sensitivity analysis to determine the information provided by observations to parameters and predictions of interest.Determine the additional data needed to improve selected model

  16. Delivery of integrated diabetes care using logistics and information technology--the Joint Asia Diabetes Evaluation (JADE) program.

    Science.gov (United States)

    Chan, Juliana C N; Ozaki, Risa; Luk, Andrea; Kong, Alice P S; Ma, Ronald C W; Chow, Francis C C; Wong, Patrick; Wong, Rebecca; Chung, Harriet; Chiu, Cherry; Wolthers, Troels; Tong, Peter C Y; Ko, Gary T C; So, Wing-Yee; Lyubomirsky, Greg

    2014-12-01

    Diabetes is a global epidemic, and many affected individuals are undiagnosed, untreated, or uncontrolled. The silent and multi-system nature of diabetes and its complications, with complex care protocols, are often associated with omission of periodic assessments, clinical inertia, poor treatment compliance, and care fragmentation. These barriers at the system, patient, and care-provider levels have resulted in poor control of risk factors and under-usage of potentially life-saving medications such as statins and renin-angiotensin system inhibitors. However, in the clinical trial setting, use of nurses and protocol with frequent contact and regular monitoring have resulted in marked differences in event rates compared to epidemiological data collected in the real-world setting. The phenotypic heterogeneity and cognitive-psychological-behavioral needs of people with diabetes call for regular risk stratification to personalize care. Quality improvement initiatives targeted at patient education, task delegation, case management, and self-care promotion had the largest effect size in improving cardio-metabolic risk factors. The Joint Asia Diabetes Evaluation (JADE) program is an innovative care prototype that advocates a change in clinic setting and workflow, coordinated by a doctor-nurse team and augmented by a web-based portal, which incorporates care protocols and a validated risk engine to provide decision support and regular feedback. By using logistics and information technology, supported by a network of health-care professionals to provide integrated, holistic, and evidence-based care, the JADE Program aims to establish a high-quality regional diabetes database to reflect the status of diabetes care in real-world practice, confirm efficacy data, and identify unmet needs. Through collaborative efforts, we shall evaluate the feasibility, acceptability, and cost-effectiveness of this "high tech, soft touch" model to make diabetes and chronic disease care more

  17. Joint Services Electronics Program.

    Science.gov (United States)

    1983-09-30

    ISEP Projects: as of 31 August 1983 B. Consolidated List of JSEP Published Papers and Memorandums through 31 August 1983 During this time period 1...for the control lines for the inter- ferometers. Receft Publications with ISEP Support "Silicon-Coupled Josephson Junctions and Super-Schottky Diodes...Rcmnt Publications uthout ISEP Spport * "Stimulated Emission of Surface Plasmons in Metal-Insulator-Degenerate p-type Semiconductor Structures," S. R

  18. Joint Services Electronics Program.

    Science.gov (United States)

    1986-09-30

    and W.E. Lamb , Jr., Phys. Rev. 181, 618 (1969); B.J. Feldman and M.S. Feld, Phys. Rev. Al, 1375 (-970); J.H. Shirley, Phys. Rev. A8, 347 (1973); V.S...Dr. Leo Young Mr. Ball Chin Office of the Deputy Under Secretary White Sands Missile Range of Defense for Research and ATTN: STEWS -ID-E Engineering (R

  19. Joint Services Electronics Program.

    Science.gov (United States)

    1981-04-01

    photolithographic technology suitable for making three-dimensional point contacts. By using an anisotropic etch, a small, pyramidal hole is defined in a wafer of...studied in detail, and strong anisotropics were observed. It was realized that these measurements provided a new and sensitive test of the standard theory...absorption data were apparently influenced by rotational hole filling by collisions. Under collisionless circumstances the ratio of the Rabi frequency to the

  20. Joint Robotics Program

    Science.gov (United States)

    2008-04-23

    Kotler , P.M. (1997). Marketing management: Analysis, planning, implementation, and control. Upper Saddle River, NJ: Prentice Hall...needed to provide needed items. Production needed to be stable so suppliers could more easily meet demand ( Kotler , 1997, pp. 214-215). The Robotics

  1. Joint Robotics Program

    National Research Council Canada - National Science Library

    Brown, Joel; Varian, Paul

    2008-01-01

    ..., then automobiles, airplanes, and rockets -- logistics too has progressed over the years: focusing first on Mass-based Supply, then Just-in-Time Supply Chain Management, and now on Sense and Respond logistics...

  2. Joint Services Electronics Program.

    Science.gov (United States)

    1985-03-30

    Siences and Systems, Baltimore, MD, March 27-29, 1985, to appear (JSEP/NSF/Kodak). 2. G. Bilardi and F. P. Preparata, "Tessellation techniques for...ADDITONAIL INFORMATION: Awards and Honors: Donna J. Broan Outstanding Young Woman of America, 1984 Member-at-Large, ACM, SIGACT1, 1983-85 * Michael C

  3. Joint Services Electronics Program.

    Science.gov (United States)

    1983-04-01

    study of controlled source audio magneto -telluric (CSAMT) surveys is in progres3. It is the logical continuation of the previous scattering problem in...heating is the insertion of an insulated antenna into a tumor to produce local hyper- thermia in conjunction with radiation therapy . This application

  4. Joint Robotics Program

    National Research Council Canada - National Science Library

    Brown, Joel; Varian, Paul

    2008-01-01

    .... Much like human transportation history evolution -- beginning first with people walking or running from point a to point b, followed by thousands of years being transported by real horse power...

  5. Joint Services Electronics Program

    Science.gov (United States)

    1982-09-30

    ntearated-Circuit Antennas and Detectors,’ David B. Rutledge. This thesis has the following abstract: Integrated-circuit technicues promise to make...D. Parxer, ADD1. Phys. Lett., 24, ,0, 1974. l-) H. F. Fetterman , B. J. Clifton, ?. E. Tannenwald, C. D. Parker, and H. Penfield, IEEE Trans...34Characteristics of Metal-Oxide-Metal Devices," Ph.D. Thesis, University of California, Berkeley, CA, 1978. (19) P. :. Tannenwald, H. R. Fetterman , C

  6. Society Influencing Science: The role of the Transdisciplinary Advisory Board (TAB) of the European Joint Programming Initiative on Climate.

    Science.gov (United States)

    Noone, K. J.; Manderscheid, P.; Monfray, P.

    2017-12-01

    It is becoming increasingly apparent that the separation between science and the rest of society is not helping us find solutions to "wicked" problems like climate change or achieving the Sustainable Development Goals. It is clear that a broader approach to research is necessary - one that includes stakeholders in the research process itself. What is unclear is how best to do this. The Transdisciplinary Advisory Board (TAB) of the European Joint Programming Initiative on Climate (JPI Climate) is an example of scientists and stakeholders working together to frame climate research and move the results of scientific research into decision support. JPI Climate is a consortium of 12 European countries (with partners from nine more countries) and is a major funding channel and forum for climate research in Europe. The TAB has an equal number of stakeholders and researchers from 10 different European countries, has an even gender balance, and its members have widely differing backgrounds. The TAB provides input and advice to the governing board of JPI Climate, and influences both the strategic planning for this funding initiative as well as specific calls for proposals issued through the consortium. In addition to its advisory role, the TAB explores the transdisciplinary process itself, expanding the boundaries of how stakeholders and science can interact positively. The TAB is a two-way mechanism through which stakeholders can help improve research and science can help improve society. We will give examples of the spectrum of how the TAB provides mutual influence between stakeholders and science - from helping to draft 10-year research strategies to helping advance the uptake of climate research into the private and policy sectors.

  7. The ERK MAP kinase-PEA3/ETV4-MMP-1 axis is operative in oesophageal adenocarcinoma

    LENUS (Irish Health Repository)

    Keld, Richard

    2010-12-09

    Abstract Background Many members of the ETS-domain transcription factor family are important drivers of tumourigenesis. In this context, their activation by Ras-ERK pathway signaling is particularly relevant to the tumourigenic properties of many ETS-domain transcription factors. The PEA3 subfamily of ETS-domain transcription factors have been implicated in tumour metastasis in several different cancers. Results Here, we have studied the expression of the PEA3 subfamily members PEA3\\/ETV4 and ER81\\/ETV1 in oesophageal adenocarcinomas and determined their role in oesophageal adenocarcinoma cell function. PEA3 plays an important role in controlling both the proliferation and invasive properties of OE33 oesophageal adenocarcinoma cells. A key target gene is MMP-1. The ERK MAP kinase pathway activates PEA3 subfamily members and also plays a role in these PEA3 controlled events, establishing the ERK-PEA3-MMP-1 axis as important in OE33 cells. PEA3 subfamily members are upregulated in human adenocarcinomas and expression correlates with MMP-1 expression and late stage metastatic disease. Enhanced ERK signaling is also more prevalent in late stage oesophageal adenocarcinomas. Conclusions This study shows that the ERK-PEA3-MMP-1 axis is upregulated in oesophageal adenocarcinoma cells and is a potentially important driver of the metastatic progression of oesophageal adenocarcinomas.

  8. The Texts of the Instruments relating to a Project for a Joint Agency-Norwegian Program of Research with the Zero Power Reactor 'NORA'

    International Nuclear Information System (INIS)

    1961-01-01

    The text of the Supply Agreement between the Agency and the Governments of Norway and of the United States of America, and the text of the related Project Agreement between the Agency and the Government of Norway concerning an Agency project for cooperation in carrying out a joint program of research in reactor physics with the zero power reactor 'NORA', are reproduced in this document for the information of all Members of the Agency

  9. The Texts of the Instruments relating to a Project for a Joint Agency-Norwegian Program of Research with the Zero Power Reactor 'NORA'

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1961-06-22

    The text of the Supply Agreement between the Agency and the Governments of Norway and of the United States of America, and the text of the related Project Agreement between the Agency and the Government of Norway concerning an Agency project for cooperation in carrying out a joint program of research in reactor physics with the zero power reactor 'NORA', are reproduced in this document for the information of all Members of the Agency.

  10. McArthur River underground exploration program: report of the joint Federal-Provincial panel on uranium mining developments in Northern Saskatchewan

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1993-01-15

    A report of the joint federal-provincial panel on uranium mining developments in northern Saskatchewan, on the McArthur River underground exploration program. The proposal to construct the surface and underground facilities required for the exploration and delineation of the McArthur River ore body, and any necessary additional infrastructure has been examined and public hearings have been held. The panel recommends that the underground exploration program as described by Cameco in its Environmental Impact Statement, and as clarified in its written and oral responses to the panel, be allowed to proceed under the conditions described within the report.

  11. McArthur River underground exploration program: report of the joint Federal-Provincial panel on uranium mining developments in Northern Saskatchewan

    International Nuclear Information System (INIS)

    1993-01-01

    A report of the joint federal-provincial panel on uranium mining developments in northern Saskatchewan, on the McArthur River underground exploration program. The proposal to construct the surface and underground facilities required for the exploration and delineation of the McArthur River ore body, and any necessary additional infrastructure has been examined and public hearings have been held. The panel recommends that the underground exploration program as described by Cameco in its Environmental Impact Statement, and as clarified in its written and oral responses to the panel, be allowed to proceed under the conditions described within the report

  12. Production of ceramic-metal joints for high-vacuum applications and development of simulation program for discharge tube

    Energy Technology Data Exchange (ETDEWEB)

    Kang, S. H.; Chung, K. H. [Seoul National University, Seoul (Korea)

    2000-04-01

    To develop a ceramic-metal jointed tube for high-vacuum applications, metalizing process and active metal brazing were investigated. Active metal brazing was adopted as a joining process to produce a high-vacuum tube which had high joint strength and reliability. A possibility for the development of new composition of Mo-Mn paste was studied. Also, to improve the strength and reliability of active metal brazed joint, TiN coating was introduced as a diffusion barrier. It was revealed that TiN coating could improve the joint strength and reliability. 100mm {phi} tube joint was produced using incusil ABA brazing alloy. The strength and reliability of manufactured tube showed higher value than commercial one. The electric field distribution in ceramic tube under high voltage was analyzed. Two dimensional electric field distribution was investigated under the existence of charged particles. From this result, electric field distribution at the surface of ceramic tube and the location of high electric field was predicted. Finally, Arc discharge was simulated to analyze the effect of arc discharge on the discharge tube wall. The maximum temperature of arc was 12000-13000K. The wall temperature was increased 100-170K by the arc discharge. 45 refs., 57 figs., 4 tabs. (Author)

  13. Regulatory perspectives on model validation in high-level radioactive waste management programs: A joint NRC/SKI white paper

    Energy Technology Data Exchange (ETDEWEB)

    Wingefors, S.; Andersson, J.; Norrby, S. [Swedish Nuclear Power lnspectorate, Stockholm (Sweden). Office of Nuclear Waste Safety; Eisenberg, N.A.; Lee, M.P.; Federline, M.V. [U.S. Nuclear Regulatory Commission, Washington, DC (United States). Office of Nuclear Material Safety and Safeguards; Sagar, B.; Wittmeyer, G.W. [Center for Nuclear Waste Regulatory Analyses, San Antonio, TX (United States)

    1999-03-01

    Validation (or confidence building) should be an important aspect of the regulatory uses of mathematical models in the safety assessments of geologic repositories for the disposal of spent nuclear fuel and other high-level radioactive wastes (HLW). A substantial body of literature exists indicating the manner in which scientific validation of models is usually pursued. Because models for a geologic repository performance assessment cannot be tested over the spatial scales of interest and long time periods for which the models will make estimates of performance, the usual avenue for model validation- that is, comparison of model estimates with actual data at the space-time scales of interest- is precluded. Further complicating the model validation process in HLW programs are the uncertainties inherent in describing the geologic complexities of potential disposal sites, and their interactions with the engineered system, with a limited set of generally imprecise data, making it difficult to discriminate between model discrepancy and inadequacy of input data. A successful strategy for model validation, therefore, should attempt to recognize these difficulties, address their resolution, and document the resolution in a careful manner. The end result of validation efforts should be a documented enhancement of confidence in the model to an extent that the model's results can aid in regulatory decision-making. The level of validation needed should be determined by the intended uses of these models, rather than by the ideal of validation of a scientific theory. This white Paper presents a model validation strategy that can be implemented in a regulatory environment. It was prepared jointly by staff members of the U.S. Nuclear Regulatory Commission and the Swedish Nuclear Power Inspectorate-SKI. This document should not be viewed as, and is not intended to be formal guidance or as a staff position on this matter. Rather, based on a review of the literature and previous

  14. Regulatory perspectives on model validation in high-level radioactive waste management programs: A joint NRC/SKI white paper

    International Nuclear Information System (INIS)

    Wingefors, S.; Andersson, J.; Norrby, S.

    1999-03-01

    Validation (or confidence building) should be an important aspect of the regulatory uses of mathematical models in the safety assessments of geologic repositories for the disposal of spent nuclear fuel and other high-level radioactive wastes (HLW). A substantial body of literature exists indicating the manner in which scientific validation of models is usually pursued. Because models for a geologic repository performance assessment cannot be tested over the spatial scales of interest and long time periods for which the models will make estimates of performance, the usual avenue for model validation- that is, comparison of model estimates with actual data at the space-time scales of interest- is precluded. Further complicating the model validation process in HLW programs are the uncertainties inherent in describing the geologic complexities of potential disposal sites, and their interactions with the engineered system, with a limited set of generally imprecise data, making it difficult to discriminate between model discrepancy and inadequacy of input data. A successful strategy for model validation, therefore, should attempt to recognize these difficulties, address their resolution, and document the resolution in a careful manner. The end result of validation efforts should be a documented enhancement of confidence in the model to an extent that the model's results can aid in regulatory decision-making. The level of validation needed should be determined by the intended uses of these models, rather than by the ideal of validation of a scientific theory. This white Paper presents a model validation strategy that can be implemented in a regulatory environment. It was prepared jointly by staff members of the U.S. Nuclear Regulatory Commission and the Swedish Nuclear Power Inspectorate-SKI. This document should not be viewed as, and is not intended to be formal guidance or as a staff position on this matter. Rather, based on a review of the literature and previous

  15. Marine mammal observations collected by aircraft and ship and submitted as part of the ConocoPhillips and Shell Joint Monitoring Program in the Chukchi and Beaufort Seas, 2006-2007 (NODC Accession 0120531)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set was collected as part of the Joint Monitoring Program during seismic activities in the Chukchi Sea. The 2006 data was collected by ship and aircraft as...

  16. Fast breeder reactor program. Hearings before the Joint Economic Committee, Congress of the United States, Ninety-Fourth Congress, First Session

    International Nuclear Information System (INIS)

    Anon.

    1976-01-01

    The economics of the liquid metal fast breeder reactor (LMFBR) was the subject of hearings of the Joint Economic Committee, chaired by Sen. Hubert Humphrey. FY '76 funding for the breeder program is $450 million, the largest single item of the Federal energy program. Elmer B. Staats, U.S. Comptroller General, testified on the rising costs of demonstration facilities and pointed out that Federal agencies are required to make all estimates of costs and benefits in constant dollars rather than projecting for inflation. Staats recommended a joint ERDA-Congressional study of the possible use of foreign breeder technology. Sheldon Meyers of the Environmental Protection Agency, while not opposing the breeder program, recommended a delay to resolve three problem areas: (1) base energy demand projections; (2) timing of the commercial introduction of the LMFBR; and (3) uncertainties over possible benefits from the LMFBR program. Theodore B. Taylor, International Research and Technology Corp., discussed the costs and security safeguards of the LMFBR, which produces more spent fuel than the light water reactor. Other witnesses included Robert Seamans and officials from ERDA, Ralph Nader, and speakers from private study groups

  17. A goal programming approach for a joint design of macroeconomic and environmental policies: a methodological proposal and an application to the Spanish economy.

    Science.gov (United States)

    André, Francisco J; Cardenete, M Alejandro; Romero, Carlos

    2009-05-01

    The economic policy needs to pay increasingly more attention to the environmental issues, which requires the development of methodologies able to incorporate environmental, as well as macroeconomic, goals in the design of public policies. Starting from this observation, this article proposes a methodology based upon a Simonian satisficing logic made operational with the help of goal programming (GP) models, to address the joint design of macroeconomic and environmental policies. The methodology is applied to the Spanish economy, where a joint policy is elicited, taking into consideration macroeconomic goals (economic growth, inflation, unemployment, public deficit) and environmental goals (CO(2), NO( x ) and SO( x ) emissions) within the context of a computable general equilibrium model. The results show how the government can "fine-tune" its policy according to different criteria using GP models. The resulting policies aggregate the environmental and the economic goals in different ways: maximum aggregate performance, maximum balance and a lexicographic hierarchy of the goals.

  18. JSPS-CAS Core University Program seminar. Proceedings of Japan-China joint seminar on atomic and molecular processes in plasma

    Energy Technology Data Exchange (ETDEWEB)

    Koike, Fumihiro [Kitasato Univ., Tokyo (Japan); Dong, Chenzhong [Northwest Normal Univ., Lanzhou (China)

    2005-02-01

    As one of the activities of JSPS-CAS Core University Program, Japan-China Joint Seminar on Atomic and Molecular Processes in Plasma was held on March 6 - 11, 2004 in Lanzhou, China. The total number of the officially registered participants was 29, in which 17 from Japan, 10 from China, and 2 from Germany. In the nuclear fusion plasma, there are quite a variety of atomic processes such as ionization, excitation, radiative recombination, non-radiative recombination (di-electronic recombination, collisional electron transfer), cascade radiation, and cascade Auger decay over the wide range of plasma temperature. The knowledge of such the processes is indispensable for the evaluation and improvement of the plasma properties, which is desirable to be investigated by international collaboration groups. The present Japan-China Joint Seminar constitutes one of such the activities to realize the above stated aim. The 21 of the presented papers are indexed individually. (J.P.N.)

  19. NOAA's Joint Polar Satellite System's (JPSS) Proving Ground and Risk Reduction (PGRR) Program - Bringing JPSS Science into Support of Key NOAA Missions!

    Science.gov (United States)

    Sjoberg, W.; McWilliams, G.

    2017-12-01

    This presentation will focus on the continuity of the NOAA Joint Polar Satellite System (JPSS) Program's Proving Ground and Risk Reduction (PGRR) and key activities of the PGRR Initiatives. The PGRR Program was established in 2012, following the launch of the Suomi National Polar Partnership (SNPP) satellite. The JPSS Program Office has used two PGRR Project Proposals to establish an effective approach to managing its science and algorithm teams in order to focus on key NOAA missions. The presenter will provide details of the Initiatives and the processes used by the initiatives that have proven so successful. Details of the new 2017 PGRR Call-for-Proposals and the status of project selections will be discussed.

  20. Hip2Norm: an object-oriented cross-platform program for 3D analysis of hip joint morphology using 2D pelvic radiographs.

    Science.gov (United States)

    Zheng, G; Tannast, M; Anderegg, C; Siebenrock, K A; Langlotz, F

    2007-07-01

    We developed an object-oriented cross-platform program to perform three-dimensional (3D) analysis of hip joint morphology using two-dimensional (2D) anteroposterior (AP) pelvic radiographs. Landmarks extracted from 2D AP pelvic radiographs and optionally an additional lateral pelvic X-ray were combined with a cone beam projection model to reconstruct 3D hip joints. Since individual pelvic orientation can vary considerably, a method for standardizing pelvic orientation was implemented to determine the absolute tilt/rotation. The evaluation of anatomically morphologic differences was achieved by reconstructing the projected acetabular rim and the measured hip parameters as if obtained in a standardized neutral orientation. The program had been successfully used to interactively objectify acetabular version in hips with femoro-acetabular impingement or developmental dysplasia. Hip(2)Norm is written in object-oriented programming language C++ using cross-platform software Qt (TrollTech, Oslo, Norway) for graphical user interface (GUI) and is transportable to any platform.

  1. Joint ventures

    DEFF Research Database (Denmark)

    Sørensen, Karsten Engsig

    Afhandlingen analysere de konkurrenceretlige og selskabsretlige regler som er bestemmende for hvordan et joint venture samarbejde er struktureret......Afhandlingen analysere de konkurrenceretlige og selskabsretlige regler som er bestemmende for hvordan et joint venture samarbejde er struktureret...

  2. Status of the joint United States/Japanese criticality data development program for the Fast Breeder fuel cycle

    International Nuclear Information System (INIS)

    Takeda, H.; Kishimoto, Y.; Matsumoto, T.; Haire, M.J.

    1987-01-01

    An experimental program is described to accumulate the basic criticality data on uranium-plutonium aqueous solution systems, including pin and water systems. This experimental program, managed by the Consolidated Fuel Reprocessing Program, utilized existing critical experiment facilities. However, Japan at least for the near future, does not have a facility for conducting critical experiments where fissible solution can be treated and processed. Therefore, Japan has remoted the existing US experimental program as well as enlarged the program so that a close cooperative relationship may exist in this area. This paper is an update of a description of the program presented in September 1985. 9 refs., 5 figs., 1 tab

  3. Coracoclavicular joint

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Kun Sang; Park, Chan Il; Ahn, Jae Doo; Lim, Chong Won [Seoul National University College of Medicine, Seoul (Korea, Republic of)

    1970-10-15

    The coracoclvicular joint, a rear abnormality which may be the cause of pain in the shoulder and limitation of motion of the shoulder joint, is discussed. A case of coracoclvicular joint with shoulder pain was observed in 65 yrs old Korean male.

  4. F-35 Joint Strike Fighter: Continued Oversight Needed as Program Plans to Begin Development of New Capabilities

    Science.gov (United States)

    2016-04-01

    material , permission from the copyright holder may be necessary if you wish to reproduce this material separately. Page 1 GAO-16-390 F-35 Joint...conducted this performance audit from June 2015 to April 2016 in accordance with generally accepted government auditing standards. Those standards...require that we plan and perform the audit to obtain sufficient, appropriate evidence to provide a reasonable basis for our findings and conclusions

  5. The selection of the American-Polish joint venture projects for the Krakow program and results of the efforts to date

    Energy Technology Data Exchange (ETDEWEB)

    Gyorke, D.F.; Butcher, T.A.

    1995-12-31

    To implement the Krakow Clean Fossil Fuels and Energy Efficiency Program, eight U.S. firms were selected by the U.S. Department of Energy to market their technologies to reduce pollution from low emission sources in Krakow. The eight U.S. firms were selected by a competitive solicitation that required the proposing firms to themselves provide funding to match or exceed the funding provided by the Program. These U.S. firms and their Polish partner companies have begun sales and cooperative work efforts in Krakow, and some have already made initial equipment installations with measurable performance improvements. Following their efforts as part of the Program, these U.S.-Polish joint ventures will market their technologies and achieve the associated environmental benefits elsewhere in Poland and Eastern and Central Europe. As part of the Krakow Program a spreadsheet model was developed to compare technological options for supplying heat to the city by calculation and comparing the heating costs and associated emissions reduction for each option. Comparison of options is made on the basis of the user cost-per-metric ton of equivalent emissions reduction. For all options considered in the Krakow Program, this cost parameter has ranged from -$1469 (best) to $2650 (worst). The costs for technologies associated with the eight projects in the Krakow Program are at the lower end of this range placing these technologies among the most cost effective solutions to the pollution problems from the low emission sources.

  6. Research on radionuclide migration under subsurface geochemical conditions. JAERI/AECL Phase II Collaborative Program Year 1 (joint research)

    International Nuclear Information System (INIS)

    1998-11-01

    A radionuclide migration experiment program for fractured rocks was performed under the JAERI/AECL Phase-II Collaborative Program on research and development in radioactive waste management. The program started in the fiscal year 1993, as a five-year program consists of Quarried block radionuclide migration program, Speciation of long-lived radionuclides in groundwater, Isotopic hydrogeology and Groundwater flow model development. During the first year of the program (Program Year 1: March 18, 1994 - September 30, 1994), a plan was developed to take out granite blocks containing part of natural water-bearing fracture from the wall of the experimental gallery at the depth of 240 m, and literature reviews were done in the area of the speciation of long-lived radionuclides in groundwater, isotopic hydrogeology and the groundwater flow model development to proceed further work for the Program Year 2. (author)

  7. [Implementation of the program of "Collaborative Development of Advanced Practical Education to Train Pharmacists in Leadership" under the joint operation of the pharmaceutical departments in fourteen national universities].

    Science.gov (United States)

    Hirata, Kazumasa; Tamura, Satoru; Kobayashi, Motomasa

    2012-01-01

    "Collaborative Development of Advanced Practical Education Program to Train Pharmacists with Leadership" applied jointly by the pharmaceutical departments of fourteen national universities was selected to receive the special expenditure support of Ministry of Education, Culture, Sports, Science and Technology for fiscal year 2010 under "the Training of Highly Skillful Professionals and Improvement of the Quality of the Function of Professional Education". This project is to promote the collaborative development of the educational program which will make it possible to further advance and substantiate the education of pharmacists in the six year course of the pharmaceutical department for the ultimate purpose to introduce pharmacists with leadership who can play an active role and fill in a leadership position in a wide range of responsibilities into the society which, more and more, has come to expect pharmacy to take the initiative in acting against health hazards caused by infections, foods and environmental pollution as well as to meet the diversification of healthcare. To be more specific, this project is to try and evaluate the following programs repeatedly based on the plan-do-check-act (PDCA) cycle: 1) Practical medical and pharmaceutical education program; 2) Program concerning research on long term themes and advanced education; 3) Program concerning training and education of SPs (standardized patients or simulated patients) and PBL (problem-based learning) tutorial education; and 4) Program concerning the method of evaluation of education. Through this repeated trial and evaluation, this project ultimately seeks to construct a highly effective practical educational program which integrates each university's achievements and educational attempts rich in originality.

  8. ENVIRONMENTAL TECHNOLOGY VERIFICATION PROGRAM: PROTOCOL FOR THE VERIFICATION OF GROUTING MATERIALS FOR INFRASTRUCTURE REHABILITATION AT THE UNIVERSITY OF HOUSTON - CIGMAT

    Science.gov (United States)

    This protocol was developed under the Environmental Protection Agency's Environmental Technology Verification (ETV) Program, and is intended to be used as a guide in preparing laboratory test plans for the purpose of verifying the performance of grouting materials used for infra...

  9. THE CONCEPTUAL MANAGEMENT FRAMEWORK OF MICROCREDIT PROVIDERS FOR ANTI-POVERTY PROGRAMS: A STUDY ON JOINT AND SEVERAL LIABILITY APPLIED IN MITRA MANINDO COOPERATIVE, NORTH SUMATERA, INDONESIA

    Directory of Open Access Journals (Sweden)

    Hartanto A.D.

    2017-07-01

    Full Text Available Microcredit program has been widely adopted by some coutries to enhance low-end enterprieses which is also a part of anti-poverty program. However, the implementation of microcredit distribution has been criticized for its high number of bad credit cases and less-optimacy in decreasing the poverty. Those problems have attracted researchers’ interest to investigate the ideal management model for microcredit program to decrease poverty cases of the members. This case-study shows that Mitra Manindo Copperative in North Sumatera has successfully decreased the poverty faced by the members through the application of the joint and several liability system (JSL. This JSL model successfully enhance the social power shared among the members by grouping method. Institutional dynamicity of the JSL application has also grown trusts among the members which appeared to be the main input to enhance the social cohesion and social capital. Strong social capital has diseminated various values that enhance the productivity of the members’ enterprises. The result of this study can be used as the proliferation in constructing ideal management procedures to apply in microcredit programs by loan providers in order to efficiently and effectively increase members’ earnings.

  10. Joint environmental assessment 1997--2001 of the California Department of Food and Agriculture Curly Top Virus Control Program for Bureau of Land Management and Department of Energy

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    The DOE, Naval Petroleum reserves in California (NPRC), proposes to sign an Amendment to the Cooperative Agreement and Supplement with the California Department of Food and Agriculture (CDFA) to extend the term of the Curly Top Virus Control Program (CTVCP) in California. This program involves Malathion spraying on NPRC lands to control the beet leafhopper, over a five year period from 1997 through 2001. It is expected that approximately 330 acres on Naval Petroleum Reserve Number 1 (NPR-1) and approximately 9,603 acres on Naval Petroleum Reserve Number 2 (NPR-2) will be treated with Malathion annually by CDFA during the course of this program. The actual acreage subject to treatment can vary from year to year. Pursuant to the requirements of the National Environmental Policy Act of 1969 (NEPA), as amended, the potential impacts of the proposed action were analyzed in a Joint Environmental Assessment (DOE/EA-1011) with the US Department of Interior, Bureau of Land Management (BLM) acting as lead agency, in consultation with the CDFA, and the DOE acting as a cooperating agency. Based on the analysis in the EA, DOE has determined that the conduct of the Curly Top Virus Control Program in California is not a major Federal action significantly affecting the quality of the human environment, within the meaning of the NEPA. Therefore, the preparation of an Environmental Impact Statement is not required and DOE is consequently issuing a FONSI.

  11. Efficiency of ETV diagrams as diagnostic tools for long-term period variations. II. Non-conservative mass transfer, and gravitational radiation

    Science.gov (United States)

    Nanouris, N.; Kalimeris, A.; Antonopoulou, E.; Rovithis-Livaniou, H.

    2015-03-01

    Context. The credibility of an eclipse timing variation (ETV) diagram analysis is investigated for various manifestations of the mass transfer and gravitational radiation processes in binary systems. The monotonicity of the period variations and the morphology of the respective ETV diagrams are thoroughly explored in both the direct impact and the accretion disk mode of mass transfer, accompanied by different types of mass and angular momentum losses (through a hot-spot emission from the gainer and via the L2/L3 points). Aims: Our primary objective concerns the traceability of each physical mechanism by means of an ETV diagram analysis. Also, possible critical mass ratio values are sought for those transfer modes that involve orbital angular momentum losses strong enough to dictate the secular period changes even when highly competitive mechanisms with the opposite direction act simultaneously. Methods: The dot{J-dot{P}} relation that governs the orbital evolution of a binary system is set to provide the exact solution for the period and the function expected to represent the subsequent eclipse timing variations. The angular momentum transport is parameterized through appropriate empirical relations, which are inferred from semi-analytical ballistic models. Then, we numerically determine the minimum temporal range over which a particular mechanism is rendered measurable, as well as the critical mass ratio values that signify monotonicity inversion in the period modulations. Results: Mass transfer rates comparable to or greater than 10-8 M⊙ yr-1 are measurable for typical noise levels of the ETV diagrams, regardless of whether the process is conservative. However, the presence of a transient disk around the more massive component defines a critical mass ratio (qcr ≈ 0.83) above which the period turns out to decrease when still in the conservative regime, rendering the measurability of the anticipated variations a much more complicated task. The effects of

  12. A Program of Research and Education in Aerospace Structures at the Joint Institute for Advancement of Flight Sciences

    Science.gov (United States)

    Tolson, Robert H.

    2000-01-01

    The objectives of the cooperative effort with NASA was to conduct research related to aerospace structures and to increase the quality and quantity of highly trained engineers knowledgeable about aerospace structures. The program has successfully met the objectives and has been of significant benefit to NASA LARC, the GWU and the nation. The program was initiated with 3 students in 1994 under the direction of Dr. Robert Tolson as the Principal Investigator. Since initiation, 14 students have been involved in the program, resulting in 11 MS degrees with 2 more expected in 2000. The 11 MS theses and projects are listed. For technology transfer purposes some research is not reported in thesis form. Graduates from the program have been hired at aerospace and other companies across the nation, providing GWU and LARC with important industry and government contacts.

  13. Temporomandibular joint

    International Nuclear Information System (INIS)

    Westesson, P.L.; Hatala, M.; Tallents, R.H.; Katzberg, R.W.; Musgrave, M.; Levitt, S.

    1990-01-01

    This paper determines the frequency of MR signs of abnormal temporomandibular joints (TMJs) in asymptomatic volunteers. Forty-two volunteers with 84 clinically normal TMJs were imaged in the sagittal and coronal planes with surface coil MR imaging. Sagittal closed and open and coronal closed views were obtained bilaterally in all volunteers. The images were classified as normal (superior disk position) or abnormal (disk displacement of degenerative joint disease). Eighteen joints in 11 volunteers were abnormal; 12 had disk displacement with reduction and six had disk displacement without reduction, with associated degenerative joint disease in three of the six. Asymptomatic internal derangement and degenerative joint disease occur in about one-fourth of asymptomatic volunteers

  14. US/French joint research program regarding the behavior of polymer base materials subjected to beta radiation: Volume 2, Phase-2a screening tests: [Final report

    International Nuclear Information System (INIS)

    Buckalew, W.H.; Wyant, F.J.; Chenion, J.; Carlin, F.; Gaussens, G.; Le Tutour, P.; Le Meur, M.

    1987-09-01

    As part of the ongoing joint NRC/CEA cooperative test program to investigate the relative effectiveness of beta and gamma irradiation to produce damage in polymer base materials, ethylene propylene rubber (EPR) specimens, in slab geometry, were exposed to Cobalt-60 gamma rays and accelerator produced electron beams. Specimens were irradiated and evaluated at research facilities in the US (Sandia National Laboratories) and France (Compagnie ORIS Industrie). These tests included several electron beam energies, sample thicknesses, exposure doses, and dose rates. Based on changes in the tensile properties, of the test specimens, results of these studies suggest that material damage resulting from electron and gamma irradiations can be correlated on the basis of absorbed radiation dose

  15. US/French Joint Research Program regarding the behavior of polymer base materials subjected to beta radiation. Volume 1. Phase-1 normalization results

    International Nuclear Information System (INIS)

    Wyant, F.J.; Buckalew, W.H.; Chenion, J.; Carlin, F.; Gaussens, G.; Le Tutour, P.; Le Meur, M.

    1986-06-01

    As part of the ongoing multi-year joint NRC/CEA international cooperative test program to investigate the dose-damage equivalence of gamma and beta radiation on polymer base materials, dosimetry and ethylene-propylene rubber (EPR) specimens were exchanged, irradiated, and evaluated for property changes at research facilities in the US (Sandia National Laboratories) and France (Compagnie ORIS Industrie). The purpose of this Phase-1 test series was to normalize and cross-correlate the results obtained by one research center to the other, in terms of exposure (1.0 MeV accelerated electrons and 60 Co gammas) and postirradiation testing (ultimate elongation and tensile strength, hardness, and density) techniques. The dosimetry and material specimen results indicate good agreement between the two countries regarding the exposure conditions and postirradiation evaluation techniques employed

  16. SIGNIFICANCE OF ETV6-RUNX1 FUSION GENE TRANSCRIPT DETECTION IN PEDIATRIC B-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA WITH TRANSLOCATION t(12;21(p13;q22

    Directory of Open Access Journals (Sweden)

    G. A. Tsaur

    2017-01-01

    Full Text Available Introduction. Translocation t(12;21(p13;q22 is one of the most common structural genetic abnormalities in childhood acute lymphoblastic leukemia (ALL. It cannot be detected by conventional G-banding, so a reverse-transcriptase polymerase chain reaction (RT-PCR or fluorescent in situ hybridization are used for this purpose.The aim of the study was to evaluate the prognostic significance of qualitative and quantitative detection of ETV6-RUNX1 fusion gene transcript at various time points in childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL patients.Materials and methods. ETV6-RUNX1 fusion gene transcript was revealed by both reverse-transcriptase PCR and quantitative real-time PCR (RQ-PCR in 34 out of 166 (20.5 % children with BCP-ALL. Qualitative ETV6-RUNX1-positivity at days 36 and 85 led to unfavorable outcome (lower event-free survival –EFS and higher cumulative incidence of relapse – CIR. While ETV6-RUNX1 status at day 15 did not allow to divide patients with different outcomes. By ROC curve analysis we determined threshold levels (TL for ETV6-RUNX1/ABL1 ratio at days 0, 15, 36 and 85. Afterwards we adjusted obtained results to 10-fold scale.Results. So practically applicable TL were as follows 500.0 %, 1 %, 0.1 % и 0.01 % for days 0, 15, 36 and 85, respectively. EFS and CIR were both worse in patients with ETV6-RUNX1/ABL1 ratio equal or above defined TL. Moreover, initial ratio ≥500,0 % corresponded to delayed blast clearance at days 15 and 36. We showed good qualitative (84.8 % and quantitative (R2 = 0.953 concordance between ETV6-RUNX1/ABL1 ratio and MRD data obtained by flow cytometry at days 15, 36, 85. Of note, defined TL for ETV6-RUNX1/ABL1 at days 15, 36, 85 were equal to prognostically important levels for flow cytometry MRD.Conclusion. Thus, qualitative detection and quantitative value of ETV6-RUNX1 fusion gene transcript showed prognostic significance in the course of treatment in children with BCP-ALL. Based

  17. First-Year Analysis of a New, Home-Based Palliative Care Program Offered Jointly by a Community Hospital and Local Visiting Nurse Service.

    Science.gov (United States)

    Pouliot, Katherine; Weisse, Carol S; Pratt, David S; DiSorbo, Philip

    2017-03-01

    There is a growing need for home-based palliative care services, especially for seriously ill individuals who want to avoid hospitalizations and remain with their regular outside care providers. To evaluate the effectiveness of Care Choices, a new in-home palliative care program provided by the Visiting Nurse Services of Northeastern New York and Ellis Medicine's community hospital serving New York's Capital District. This prospective cohort study assessed patient outcomes over the course of 1 year for 123 patients (49 men and 74 women) with serious illnesses who were new enrollees in the program. Quality of life was assessed at baseline and after 1 month on service. Satisfaction with care was measured after 1 and 3 months on service. The number of emergency department visits and inpatient hospitalizations pre- and postenrollment was measured for all enrollees. Patients were highly satisfied (72.7%-100%) with their initial care and reported greater satisfaction ( P care service. An in-home palliative care program offered jointly through a visiting nurse service and community hospital may be a successful model for providing quality care that satisfies chronically ill patients' desire to remain at home and avoid hospital admissions.

  18. Joint NASA/USAF Airborne Field Mill Program - Operation and safety considerations during flights of a Lear 28 airplane in adverse weather

    Science.gov (United States)

    Fisher, Bruce D.; Phillips, Michael R.; Maier, Launa M.

    1992-01-01

    A NASA Langley Research Center Learjet 28 research airplane was flown in various adverse weather conditions in the vicinity of the NASA Kennedy Space Center from 1990-1992 to measure airborne electric fields during the Joint NASA/USAF Airborne Field Mill Program. The objective of this program was to characterize the electrical activity in various weather phenomena common to the NASA-Kennedy area in order to refine Launch Commit Criteria for natural and triggered lightning. The purpose of the program was to safely relax the existing launch commit criteria, thereby increasing launch availability and reducing the chance for weather holds and delays. This paper discusses the operational conduct of the flight test, including environmental/safety considerations, aircraft instrumentation and modification, test limitations, flight procedures, and the procedures and responsibilities of the personnel in the ground station. Airborne field mill data were collected for all the Launch Commit Criteria during two summer and two winter deployments. These data are now being analyzed.

  19. Determination of Parachute Joint Factors using Seam and Joint Testing

    Science.gov (United States)

    Mollmann, Catherine

    2015-01-01

    This paper details the methodology for determining the joint factor for all parachute components. This method has been successfully implemented on the Capsule Parachute Assembly System (CPAS) for the NASA Orion crew module for use in determining the margin of safety for each component under peak loads. Also discussed are concepts behind the joint factor and what drives the loss of material strength at joints. The joint factor is defined as a "loss in joint strength...relative to the basic material strength" that occurs when "textiles are connected to each other or to metals." During the CPAS engineering development phase, a conservative joint factor of 0.80 was assumed for each parachute component. In order to refine this factor and eliminate excess conservatism, a seam and joint testing program was implemented as part of the structural validation. This method split each of the parachute structural joints into discrete tensile tests designed to duplicate the loading of each joint. Breaking strength data collected from destructive pull testing was then used to calculate the joint factor in the form of an efficiency. Joint efficiency is the percentage of the base material strength that remains after degradation due to sewing or interaction with other components; it is used interchangeably with joint factor in this paper. Parachute materials vary in type-mainly cord, tape, webbing, and cloth -which require different test fixtures and joint sample construction methods. This paper defines guidelines for designing and testing samples based on materials and test goals. Using the test methodology and analysis approach detailed in this paper, the minimum joint factor for each parachute component can be formulated. The joint factors can then be used to calculate the design factor and margin of safety for that component, a critical part of the design verification process.

  20. Engaging the Public Through a Joint Outreach Program with the Appalachian Mountain Club - A Successful First Year

    Science.gov (United States)

    Arion, Douglas N.; DeLucia, S.; Anderson, K.; Tatge, C.; Troyer, Z. D.

    2013-01-01

    Carthage College and the Appalachian Mountain Club (AMC) formed a partnership to deliver hands-on astronomy programs to the public, train mentors and docents, and provide experiential learning opportunities for astronomy students. In its first year of operation the program reached over 2000 visitors, and engaged them in daytime and nighttime observing, lectures and presentations, and workshops. The AMC serves more than 500,000 visitors each year at its lodges, centers, and high-mountain huts and delivers a wealth of experiences in nature and the environment. Through this project Carthage and the AMC have added astronomy to the education programming to provide a holistic, integrative picture of the workings of the universe to the lay public. The presentations given are atypical of astronomy outreach, as they emphasize the physical connections and linkages among many disciplines with astronomy. For example, the coincidence between eye color sensitivity and the solar spectrum; the evolutionary patterns that resulted from asteroid impacts; and the seasonal variation in animal coat colors are emphasized as much as the scale of the Universe and the typical stellar nucleosynthesis (the ‘we are stardust’ analogy) that are often covered. An extensive evaluation and assessment process has been implemented, and results of those studies show significant impact on participants. Participants ranged from older, more experienced AMC visitors to elementary and middle school students in the Mountain Classroom program, as well as a wide range of visitors from across the country. In addition to these programs, training workshops have been implemented for all AMC staff who work with the public, including those at the high mountain huts, the naturalists, and AMC volunteers. This work was supported in part by the National Science Foundation AST Division.

  1. Theoretical analysis of rolled joints

    International Nuclear Information System (INIS)

    Sinha, R.K.

    1975-01-01

    A procedure for theoretically analysing the case of an externally restrained sandwich joint formed by a hypothetical uniform hydrostatic expansion process is outlined. Reference is made to a computer program based on this theory. Results illustrating the effect of major joint variables on residual contact pressure are presented and analysed. The applicability and limitations of this theory are discussed. (author)

  2. Environmental Technology Verification Coatings and Coating Equipment Program (ETV CCEP). High Transfer Efficiency Spray Equipment - Generic Verification Protocol (Revision 0)

    Science.gov (United States)

    2006-09-30

    High-Pressure Waterjet • CO2 Pellet/Turbine Wheel • Ultrahigh-Pressure Waterjet 5 Process Water Reuse/Recycle • Cross-Flow Microfiltration ...documented on a process or laboratory form. Corrective action will involve taking all necessary steps to restore a measuring system to proper working order...In all cases, a nonconformance will be rectified before sample processing and analysis continues. If corrective action does not restore the

  3. Joint diseases

    International Nuclear Information System (INIS)

    Weissman, S.D.

    1989-01-01

    The authors discuss how x-ray examination is essential in the diagnosis and evaluation of the arthritides. Most arthritides are first suspected by the clinician, and x-ray evaluation of these entities along with laboratory testing is important for confirmation of the clinical diagnosis and in staging of the disease process. Several arthritides are often diagnosed first by the podiatrist on x-ray evaluation, including pseudogout, ankylosing spondylitis, early rheumatoid arthritis, degenerative joint disease, and tuberculosis of bone. The joint responds to insult in only a limited number of ways that become apparent on x-ray. The soft tissues surrounding the joint, the articulating bones, and alignment of the joint space may all be involved by the arthritic process. On roentgenographic examination, the soft tissues must be examined for edema, masses, calcifications, and atrophy. The articulating bones must be examined for demineralization, erosions, osteophytes, periosteal reaction, cysts and sclerosis

  4. Joint pain

    Science.gov (United States)

    ... or conditions. It may be linked to arthritis , bursitis , and muscle pain . No matter what causes it, ... Autoimmune diseases such as rheumatoid arthritis and lupus Bursitis Chondromalacia patellae Crystals in the joint: Gout (especially ...

  5. Finding of no significant impact for the joint DOE/EPA program on national industrial competitiveness through energy efficiency and economics (NICE{sup 3})

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    The Department of Energy (DOE) has prepared a Programmatic Environmental Assessment (PEA), to assess the environment impacts associated with a joint DOE/EPA cost-sharing grant program named National Industrial Competitiveness through Energy Efficiency, Environment and Economics (NICE{sup 3}). The purpose of the NICE{sup 3} Program is to encourage waste minimization technology in industry by funding projects that develop activities and process improvements to conserve energy and reduce pollution. The proposed action would provide Federal financial assistance in the form of grants to industry in order to promote pollution prevention, energy efficiency, and cost competitiveness. Based on the analysis presented in the PEA, DOE has determined that the proposed action (providing NICE{sup 3} grants for projects which are consistent with the goals of the PPA and EPACT) does not constitute a major Federal action significantly affecting the quality of the human environment within the meaning of NEPA. Therefore, the preparation of an Environmental Impact Statement is not needed and the Department is issuing this Finding of No Significant Impact.

  6. Cost effective safety enhancements for research reactors in Uzbekistan and Kazakhstan - results of a joint program with US DOE

    International Nuclear Information System (INIS)

    Earle, O.K.; Carlson, R.B.; Rakhmanov, A.; Salikhbaev, U.S.; Chernyaev, V.; Chakrov, P.

    2004-01-01

    The US Department of Energy's Office of International Nuclear Safety and Cooperation established the Integrated Research Reactor Safety Enhancement Program (IRRSEP) in February 2002 to support U.S. nonproliferation goals by implementing safety upgrades, or assisting with the safe shutdown and decommissioning of foreign test and research reactors which present security concerns. IRRSEP's key program components are: Phase I: Self-evaluation by facility using provided checklists followed by prioritization to identify the 20 highest risk facilities; Phase II: Site visits with technical evaluation to finalize a list of projects that will enhance safety consistent with IAEA observations; Phase III: Corrective measures to implement the projects. Phases I, II and III are accomplished on a rolling basis, such that work is ongoing at three or four reactors per year. IRRSEP's key objective is to resolve the highest-priority nuclear safety issues at the most vulnerable foreign research reactors as quickly as possible. The prioritization methodology employed identified which research reactors fell into this category. The corrective measures mutually developed with the host facility are based on the premise of developing a sustainable infrastructure within each country to deal with its own nuclear material safety, security, and response issues in the future. IRRSEP also assists in creating an international framework of cooperation and openness between research and test reactor operators, and national and international regulators. The initial projects under IRRSEP are underway at research reactors in Kazakhstan, Uzbekistan, and Romania. This paper focuses on the projects undertaken at the WWR-K research reactor at the Institute of Nuclear Physics in Alatau, Kazakhstan and the WWR-SM research reactor at the Institute of Nuclear Physics in Ulugbek, Uzbekistan. These projects demonstrate the success and cost effectiveness of the IRRSEP program

  7. Cost effective safety enhancements for research reactors in Uzbekistan and Kazakhstan - results of a joint program with US DOE

    International Nuclear Information System (INIS)

    Earle, O.K.; Carlson, R.B.; Rakhmanov, A.; Salikhbaev, U.S.; Chernyaev, V.; Chakrov, P.

    2004-01-01

    Full text: The US Department of Energy's Office of International Nuclear Safety and Cooperation established the Integrated Research Reactor Safety Enhancement Program (IRRSEP) in February 2002 to support U.S. nonproliferation goals by (1) implementing safety upgrades, or (2) assisting with the safe shutdown and decommissioning of foreign test and research reactors which present security concerns. IRRSEP's key program components are: Phase I: Self-evaluation by facility using provided checklists followed by prioritization to identify the 20 highest risk facilities; Phase II: Site visits with technical evaluation to finalize a list of projects that will enhance safety consistent with IAEA observations; Phase III: Corrective measures to implement the projects. Phases I, II and III are accomplished on a rolling basis, such that work is ongoing at three or four reactors per year. IRRSEP's key objective is to resolve the highest-priority nuclear safety issues at the most vulnerable foreign research reactors as quickly as possible. The prioritization methodology employed identified which research reactors fell into this category. The corrective measures mutually developed with the host facility are based on the premise of developing a sustainable infrastructure within each country to deal with its own nuclear material safety, security, and response issues in the future. IRRSEP also assists in creating an international framework of cooperation and openness between research and test reactor operators, and national and international regulators. The initial projects under IRRSEP are underway at research reactors in Kazakhstan, Uzbekistan, and Romania. This paper focuses on the projects undertaken at the WWR-K research reactor at the Institute of Nuclear Physics in Alatau, Kazakhstan and the WWR-SM research reactor at the Institute of Nuclear Physics in Ulugbek, Uzbekistan. These projects demonstrate the success and cost effectiveness of the IRRSEP program

  8. Joint Performance and Planning System

    Data.gov (United States)

    US Agency for International Development — A joint State/USAID system hosted by State that integrates resource and performance information at the program level and enables more flexible and frequent entry of...

  9. The leukemia-specific fusion gene ETV6/RUNX1 perturbs distinct key biological functions primarily by gene repression.

    Directory of Open Access Journals (Sweden)

    Gerhard Fuka

    Full Text Available BACKGROUND: ETV6/RUNX1 (E/R (also known as TEL/AML1 is the most frequent gene fusion in childhood acute lymphoblastic leukemia (ALL and also most likely the crucial factor for disease initiation; its role in leukemia propagation and maintenance, however, remains largely elusive. To address this issue we performed a shRNA-mediated knock-down (KD of the E/R fusion gene and investigated the ensuing consequences on genome-wide gene expression patterns and deducible regulatory functions in two E/R-positive leukemic cell lines. FINDINGS: Microarray analyses identified 777 genes whose expression was substantially altered. Although approximately equal proportions were either up- (KD-UP or down-regulated (KD-DOWN, the effects on biological processes and pathways differed considerably. The E/R KD-UP set was significantly enriched for genes included in the "cell activation", "immune response", "apoptosis", "signal transduction" and "development and differentiation" categories, whereas in the E/R KD-DOWN set only the "PI3K/AKT/mTOR signaling" and "hematopoietic stem cells" categories became evident. Comparable expression signatures obtained from primary E/R-positive ALL samples underline the relevance of these pathways and molecular functions. We also validated six differentially expressed genes representing the categories "stem cell properties", "B-cell differentiation", "immune response", "cell adhesion" and "DNA damage" with RT-qPCR. CONCLUSION: Our analyses provide the first preliminary evidence that the continuous expression of the E/R fusion gene interferes with key regulatory functions that shape the biology of this leukemia subtype. E/R may thus indeed constitute the essential driving force for the propagation and maintenance of the leukemic process irrespective of potential consequences of associated secondary changes. Finally, these findings may also provide a valuable source of potentially attractive therapeutic targets.

  10. A small molecule inhibitor of ETV1, YK-4-279, prevents prostate cancer growth and metastasis in a mouse xenograft model.

    Directory of Open Access Journals (Sweden)

    Said Rahim

    Full Text Available The erythroblastosis virus E26 transforming sequences (ETS family of transcription factors consists of a highly conserved group of genes that play important roles in cellular proliferation, differentiation, migration and invasion. Chromosomal translocations fusing ETS factors to promoters of androgen responsive genes have been found in prostate cancers, including the most clinically aggressive forms. ERG and ETV1 are the most commonly translocated ETS proteins. Over-expression of these proteins in prostate cancer cells results in a more invasive phenotype. Inhibition of ETS activity by small molecule inhibitors may provide a novel method for the treatment of prostate cancer.We recently demonstrated that the small molecule YK-4-279 inhibits biological activity of ETV1 in fusion-positive prostate cancer cells leading to decreased motility and invasion in-vitro. Here, we present data from an in-vivo mouse xenograft model. SCID-beige mice were subcutaneously implanted with fusion-positive LNCaP-luc-M6 and fusion-negative PC-3M-luc-C6 tumors. Animals were treated with YK-4-279, and its effects on primary tumor growth and lung metastasis were evaluated. YK-4-279 treatment resulted in decreased growth of the primary tumor only in LNCaP-luc-M6 cohort. When primary tumors were grown to comparable sizes, YK-4-279 inhibited tumor metastasis to the lungs. Expression of ETV1 target genes MMP7, FKBP10 and GLYATL2 were reduced in YK-4-279 treated animals. ETS fusion-negative PC-3M-luc-C6 xenografts were unresponsive to the compound. Furthermore, YK-4-279 is a chiral molecule that exists as a racemic mixture of R and S enantiomers. We established that (S-YK-4-279 is the active enantiomer in prostate cancer cells.Our results demonstrate that YK-4-279 is a potent inhibitor of ETV1 and inhibits both the primary tumor growth and metastasis of fusion positive prostate cancer xenografts. Therefore, YK-4-279 or similar compounds may be evaluated as a potential

  11. Report on the joint USA-Germany drop test program for a vitrified high level waste cask

    International Nuclear Information System (INIS)

    Golliher, K.G.; Witt, C.R.; Wieser, K.E.

    1993-01-01

    A series of full-scale drop tests was performed on a ductile iron transport cask in a cooperative program between the US Department of Energy (DOE) and Bundesantalt fuer Materialpruefung (BAM) in Germany. The tests, which were performed at BAM's test facility located near Lehre, Germany, were performed on a prototype cask designed for transport of Vitrified High Level Waste (VHLW) canisters. The VHLW cask is a right circular cylinder with a diameter of 1156 mm and a height of 3454 cm, and weighs approximately 24.6 kg including its payload of a single VHLW canister. The drop tests were performed with a non-radioactive, prototype VHLW canister in the cavity. (J.P.N.)

  12. The Live program - Results of test L1 and joint analyses on transient molten pool thermal hydraulics

    Energy Technology Data Exchange (ETDEWEB)

    Buck, M.; Buerger, M. [Univ Stuttgart, Inst Kernenerget and Energiesyst, D-70569 Stuttgart (Germany); Miassoedov, A.; Gaus-Liu, X.; Palagin, A. [IRSN Forschungszentrum Karlsruhe GmbH, D-76021 Karlsruhe, (Germany); Godin-Jacqmin, L. [CEA Cadarache, DEN STRI LMA, F-13115 St Paul Les Durance (France); Tran, C. T.; Ma, W. M. [KTH, AlbaNova Univ Ctr, S-10691 Stockholm (Sweden); Chudanov, V. [Nucl Safety Inst, Moscow 113191 (Russian Federation)

    2010-07-01

    The development of a corium pool in the lower head and its behaviour is still a critical issue. This concerns, in general, the understanding of a severe accident with core melting, its course, major critical phases and timing, and the influence of these processes on the accident progression as well as, in particular, the evaluation of in-vessel melt retention by external vessel flooding as an accident mitigation strategy. Previous studies were especially related to the in-vessel retention question and often just concentrated on the quasi-steady state behaviour of a large molten pool in the lower head, considered as a bounding configuration. However, non-feasibility of the in-vessel retention concept for high power density reactors and uncertainties e. g. due to layering effects even for low or medium power reactors, turns this to be insufficient. Rather, it is essential to consider the whole evolution of the accident, including e. g. formation and growth of the in-core melt pool, characteristics of corium arrival in the lower head, and molten pool behaviour after the debris re-melting. These phenomena have a strong impact on a potential termination of a severe accident. The general objective of the LIVE program at FZK is to study these phenomena resulting from core melting experimentally in large-scale 3D geometry and in supporting separate-effects tests, with emphasis on the transient behaviour. Up to now, several tests on molten pool behaviour have been performed within the LIVE experimental program with water and with non-eutectic melts (KNO{sub 3}-NaNO{sub 3}) as simulant fluids. The results of these experiments, performed in nearly adiabatic and in isothermal conditions, allow a direct comparison with findings obtained earlier in other experimental programs (SIMECO, ACOPO, BALI, etc. ) and will be used for the assessment of the correlations derived for the molten pool behaviour. Complementary to other international programs with real corium melts, the results

  13. Gene fusions AHRR-NCOA2, NCOA2-ETV4, ETV4-AHRR, P4HA2-TBCK, and TBCK-P4HA2 resulting from the translocations t(5;8;17)(p15;q13;q21) and t(4;5)(q24;q31) in a soft tissue angiofibroma.

    Science.gov (United States)

    Panagopoulos, Ioannis; Gorunova, Ludmila; Viset, Trond; Heim, Sverre

    2016-11-01

    We present an angiofibroma of soft tissue with the karyotype 46,XY,t(4;5)(q24;q31),t(5;8;17)(p15;q13;q21)[8]/46,XY,t(1;14)(p31;q32)[2]/46,XY[3]. RNA‑sequencing showed that the t(4;5)(q24;q31) resulted in recombination of the genes TBCK on 4q24 and P4HA2 on 5q31.1 with generation of an in‑frame TBCK‑P4HA2 and the reciprocal but out‑of‑frame P4HA2‑TBCK fusion transcripts. The putative TBCK‑P4HA2 protein would contain the kinase, the rhodanese‑like domain, and the Tre‑2/Bub2/Cdc16 (TBC) domains of TBCK together with the P4HA2 protein which is a component of the prolyl 4‑hydroxylase. The t(5;8;17)(p15;q13;q21) three‑way chromosomal translocation targeted AHRR (on 5p15), NCOA2 (on 8q13), and ETV4 (on 17q21) generating the in‑frame fusions AHRR‑NCOA2 and NCOA2‑ETV4 as well as an out‑of‑frame ETV4‑AHRR transcript. In the AHRR‑NCOA2 protein, the C‑terminal part of AHRR is replaced by the C‑terminal part of NCOA2 which contains two activation domains. The NCOA2‑ETV4 protein would contain the helix‑loop‑helix, PAS_9 and PAS_11, CITED domains, the SRC‑1 domain of NCOA2 and the ETS DNA‑binding domain of ETV4. No fusion gene corresponding to t(1;14)(p31;q32) was found. Our findings indicate that, in spite of the recurrence of AHRR‑NCOA2 in angiofibroma of soft tissue, additional genetic events (or fusion genes) might be required for the development of this tumor.

  14. Electric and hybrid vehicle program. Quarterly report, January-February-March 1981

    Energy Technology Data Exchange (ETDEWEB)

    1981-05-01

    Highlights of program developments are discussed, and ETV-1 test results are described. The temperature effects on lead-acid battery performance from 27 to 55/sup 0/C are reported, and the status of demonstration electric vehicle orders and deliveries is summarized. The certification and testing status of demonstration project vehicles is outlined, and a personnel directory for the DOE Electric and Hybrid Vehicle Program is included. (WHK)

  15. Joint Intentionality

    Directory of Open Access Journals (Sweden)

    Koreň Ladislav

    2016-03-01

    Full Text Available According to the shared intentionality hypothesis proposed by Michael Tomasello, two cognitive upgrades – joint and collective intentionality, respectively – make human thinking unique. Joint intentionality, in particular, is a mindset supposed to account for our early, species-specific capacity to participate in collaborative activities involving two (or a few agents. In order to elucidate such activities and their proximate cognitive-motivational mechanism, Tomasello draws on philosophical accounts of shared intentionality. I argue that his deference to such cognitively demanding accounts of shared intentional activities is problematic if his theoretical ambition is in part to show that and how early (prelinguistic and precultural capacities for joint action contribute to the development of higher cognitive capacities.

  16. NASA/University JOint VEnture (JOVE) Program. VIXEN(tm): Object-Oriented, Technology-Adaptive, Virtual Information Exchange Environment

    Science.gov (United States)

    Anyiwo, Joshua C.

    2000-01-01

    Vixen is a collection of enabling technologies for uninhibited distributed object computing. In the Spring of 1995 when Vixen was proposed, it was an innovative idea very much ahead of its time. But today the technologies proposed in Vixen have become standard technologies for Enterprise Computing. Sun Microsystems J2EE/EJB specifications, among others, are independently proposed technologies of the Vixen type. I have brought Vixen completely under the J2EE standard in order to maximize interoperability and compatibility with other computing industry efforts. Vixen and the Enterprise JavaBean (EJB) Server technologies are now practically identical; OIL, another Vixen technology, and the Java Messaging System (JMS) are practically identical; and so on. There is no longer anything novel or patentable in the Vixen work performed under this grant. The above discussion, notwithstanding, my independent development of Vixen has significantly helped me, my university, my students and the local community. The undergraduate students who worked with me in developing Vixen have enhanced their expertise in what has become the cutting edge technology of their industry and are therefore well positioned for lucrative employment opportunities in the industry. My academic department has gained a new course: "Multi-media System Development", which provides a highly desirable expertise to our students for employment in any enterprise today. The many Outreach Programs that I conducted during this grant period have exposed local Middle School students to the contributions that NASA is making in our society as well as awakened desires in many such students for careers in Science and Technology. I have applied Vixen to the development of two software packages: (a) JAS: Joshua Application Server - which allows a user to configure an EJB Server to serve a J2EE compliant application over the world wide web; (b) PCM: Professor Course Manager: a J2EE compliant application for configuring a

  17. JSPS-CAS Core University Program seminar. Proceedings of Japan-China joint seminar on atomic and molecular processes in plasma

    International Nuclear Information System (INIS)

    Koike, Fumihiro; Dong Chenzhong

    2010-02-01

    As one of the activities of JSPS-CAS Core University Program, Japan-China Joint Seminar on Atomic and Molecular Processes in Plasma was held on October 26 - 31, 2009 in Xi'an, China. The total number of the officially registered participants was 54, in which 18 from Japan, 35 from China, and 1 from USA. And this seminar is an extension of the last two seminars that were held on March 6 - 11, 2004 in Lanzhou, China, and on October 6 - 12, 2007 in Dunhuang, China. In the nuclear fusion plasma, there are quite a variety of atomic processes such as ionization, excitation, radiative recombination, non-radiative recombination (di-electronic recombination, collisional electron transfer), cascade radiation, and cascade Auger decay over the wide range of plasma temperature. The knowledge of those processes is indispensable for the evaluation and improvement of the plasma properties. Because of the diversity of the subject, it is desirable to investigate them by international collaboration groups. The present seminar may contribute to realize the above stated aim; especially it has given an opportunity for the collaborative workers to illustrate their achievements. This seminar summarizes the collaborative researches for the last decade and propose the issues for the future prospect. The 30 of the presented papers are indexed individually. (J.P.N.)

  18. Mathematical Modelling of a Friction Stir Welding Process to Predict the Joint Strength of Two Dissimilar Aluminium Alloys Using Experimental Data and Genetic Programming

    Directory of Open Access Journals (Sweden)

    Mohammed Yunus

    2018-01-01

    Full Text Available Friction stir welding (FSW is the most popular and efficient method of solid-state joining for similar as well as dissimilar metals and alloys. It is mostly used in applications for aerospace, rail, automotive, and marine industries. Many researchers are currently working with different perspectives on this FSW process for various combinations of materials. The general input process parameters are the thickness of the plate, axial load, rotational speed, welding speed, and tilt angle. The output parameters are joint hardness, % of elongation, and impact and yield strengths. Genetic programming (GP is a relatively new method of evolutionary computing with the principal advantage of this approach being to evaluate efficacious predictive mathematical models or equations without any prior assumption regarding the possible form of the functional relationship. This paper both defines and illustrates how GP can be applied to the FSW process to derive precise relationships between the output and input parameters in order to obtain a generalized prediction model. A GP model will assist engineers in quantifying the performance of FSW, and the results from this study can then be utilized to estimate future requirements based on the historical data to provide a robust solution. The obtained results from the GP models showed good agreement with experimental and target data at an average prediction error of 0.72%.

  19. JSPS-CAS core university program seminar. Proceedings of Japan-China joint seminar on atomic and molecular processes in plasma

    International Nuclear Information System (INIS)

    Koike, Fumihiro; Dong Chenzhong

    2008-03-01

    As one of the activities of JSPS-CAS Core University Program, Japan-China Joint Seminar on Atomic and Molecular Processes in Plasma was held on October 8 - 12, 2007 in Dunhuang, China. The total number of the officially registered participants was 41, in which 12 from Japan, 25 from China, and 4 from EU. And this seminar is an extension of the last seminar that was held on March 6 - 11, 2004 in Lanzhou, China. In the nuclear fusion plasma, there are quite a variety of atomic processes such as ionization, excitation, radiative recombination, non-radiative recombination (di-electronic recombination, collisional electron transfer), cascade radiation, and cascade Auger decay over the wide range of plasma temperature. The knowledge of such processes is indispensable for the evaluation and improvement of the plasma properties, which is desirable to be investigated by international collaboration groups. The present seminar constitutes one of such activities to realize the above stated aim; especially it has given an opportunity for the collaborative workers to illustrate their achievements. The 32 of the presented papers are indexed individually. (J.P.N.)

  20. JSPS-NRF-NSFC A3 foresight program seminar. Proceedings of Japan-China-Korea joint seminar on atomic and molecular processes in plasma

    International Nuclear Information System (INIS)

    Kato, Daiji; Ding Xiaobin; Dong Chenzhong

    2016-02-01

    As one of the activities of JSPS-NRF-NSFC A3 Foresight Program in the field of Plasma Physics 'Study on Critical Physics Issues Specific to Steady State Sustainment of High-Performance Plasmas', Japan-China-Korea Joint Seminar on Atomic and Molecular Processes in Plasma (AMPP2015) was held on July 28 - August 1, 2014, in Lanzhou, China. The total number of the officially registered participants was 50. This seminar is the extension of the last four seminars that were held in 2004 in Lanzhou, in 2007 in Dunhuang, in 2009 in Xi'an, and in 2012 in Lanzhou. In the nuclear fusion plasma, there are quite a variety of atomic processes such as ionization, excitation, di-electronic recombination, collisional electron transfer, cascade radiation, and cascade Auger decay over the wide range of plasma temperature. The knowledge of those processes is indispensable for the evaluation and improvement of the plasma properties. Because of the diversity of the subjects, it is desirable to investigate them by international collaboration groups. This seminar is held to discuss achievement during the past two years and issues for the future prospect. This issue is the collection of 16 papers presented at the entitled meeting. All the 16 presented papers are indexed individually. (J.P.N.)

  1. Joint imaging

    International Nuclear Information System (INIS)

    Hengst, W.

    1984-01-01

    Joint imaging is a proven diagnostic procedure which has become indispensable to the detection and treatment of different joint diseases in almost all disciplines. The method is suited for early diagnosis of joint affections both in soft tissue and bone which cannot be detected by X-ray or other procedures. The local activity accumulation depends on the rate of metabolism and is visualized in the scan, which in turn enables the extension and floridity of focal lesions to be evaluated and followed-up. Although joint scans may often give hints to probabilities relevant to differential diagnosis, the method is non-specific and only useful if based on the underlying clinical picture and X-ray finding, if possible. The radiation exposure is very low and does not represent a hazard in cases of adequate assessment of indication. In pregnant women and children the assessment of indication has to be based on very strict principles. The method is suited for out-patient diagnosis and can be applied in all installations equipped with a gamma camera and a technetium generator. (orig.) [de

  2. Joint purpose?

    DEFF Research Database (Denmark)

    Pristed Nielsen, Helene

    2013-01-01

    Starting from Crenshaw´s point that antiracism often fails to interrogate patriarchy and that feminism often reproduces racist practices (1991: 1252), this paper asks: What are the theoretical reasons for believing that feminism and anti-racism can be regarded as fighting for the joint purpose...

  3. History of the biomedical studies PhD program: a joint graduate program of the Baylor Health Care system and Baylor University.

    Science.gov (United States)

    Morel, Christine R; Horton, Joshua M; Peng, Han; Xu, Kangling; Batra, Sushil K; Miles, Jonathan P; Kane, Robert R

    2008-10-01

    On a sweltering summer morning, throngs of people filed into Jones Theatre at Baylor University in Waco for the graduate student orientation. One could look around and notice the diversity of not only the student population, but also the disciplines being represented. Many students had stepped off planes only hours prior, but even those who had been traveling for days could not contain their excitement. As for me, I was nowhere near any of this. I was still 40 miles north of Waco in Waxahachie, having been pulled over for speeding. After 4 days of traveling with my life in my Volkswagon Jetta, all the way from San Francisco, on one of the most important days of my life, I was late. When I finally arrived at the Hooper Schafer Fine Arts Auditorium, out of breath from running all the way from the parking structure, all of the graduate students were quietly listening to the first introductory speech. I snuck into the back and sat down. My mind was racing, as I knew very little about Waco and Baylor University except for the growing accomplishments of the biomedical studies program. What little I did know about Baylor seemed so different from my very liberal upbringing in California. What would this experience be like for me? But, as I listened to the talks, met with other students, and finally met the entire biomedical studies entering class of 2007, I knew that I had made the right decision in coming to Baylor. This would be an experience unlike any other, and I was wholeheartedly open to embracing it. -Christine Morel, PhD candidate, Institute of Biomedical Studies.

  4. Myeloid Neoplasms with t(5;12 and ETV6-ACSL6 Gene Fusion, Potential Mimickers of Myeloid Neoplasm with PDGFRB Rearrangement: Case Report with Imatinib Therapy and Review of the Literature

    Directory of Open Access Journals (Sweden)

    Javier De Luca-Johnson

    2016-01-01

    Full Text Available We report the second case of ETV6-ACSL6 associated myeloproliferative neoplasm that has received a full course of imatinib therapy. The patient was a 51-year-old previously healthy man who presented with three months of worsening dyspnea and was found to have a white count of 216,000/cmm, of which 84% were eosinophil lineage. Cytogenetic analysis revealed a t(5;12(q31~33;p13. FISH was negative for PDGFRB rearrangement but additional FISH testing demonstrated an ACSL6 rearrangement. ETV6-ACSL6 gene fusion is a rare abnormality that most often presents as a myeloproliferative-type disorder with prominent eosinophilia or basophilia. Review of the literature yielded a total of 11 previous cases. This gene fusion results in a t(5;12(q31~33;p13 that mimics the t(5;12 found in ETV6-PDGFRB neoplasms. Identification of the fusion genes involved in t(5;12 in eosinophilia-associated myeloproliferative disorders is crucial to direct an effective treatment plan. In particular, while tyrosine kinase inhibitor therapy is effective in patients with PDGFRB rearrangement, there is little information on imatinib efficacy in patients with ETV6-ACSL6 gene fusion. Our patient was found to be nonresponsive to imatinib therapy.

  5. Efficacy of Caregiver-Mediated Joint Engagement Intervention for Young Children with Autism Spectrum Disorders

    Science.gov (United States)

    Chiang, Chung-Hsin; Chu, Ching-Lin; Lee, Tsung-Chin

    2016-01-01

    Joint attention intervention for children with autism spectrum disorders was focused on improving joint engagement and joint attention skills. The purpose of this study was to develop a caregiver-mediated joint engagement intervention program combined with body movement play to investigate the effects of joint engagement/joint attention skills in…

  6. National Guard Bureau Joint Staff

    Science.gov (United States)

    Civic Leader's Guide ARNG Vision 2020 Posture Statement Strategic Direction CNGB ARNG Financial Report Marshal Office of the Joint Surgeon PARC Small Business Programs Chaplain Diversity NGB-GOMO Resources Legislative Liaison Small Business Programs Social Media State Websites Videos Featured Videos On Every Front

  7. Joint Services Electronics Program. Appendix

    Science.gov (United States)

    1992-11-01

    R.E. Kleinman, Electromagnetic and (Raleigh- Ritz ), Galerkins method, and the method of Acoustic Scattering by Simple Shapes, J.J. Bowman, least...71 C. Namislo, "Analysis of mobile radio slotted ALOHA networks," IEEE the M. Barry Carlton Award for best paper from the IEEE Aerospace and Tram

  8. Joint Civilian Orientation Conference Program

    Science.gov (United States)

    2009-12-09

    duplicate payment of $1,064 to the contractor for dinner costs at the Star of Honolulu restaurant on November 4, 2007. The documentation the...some, if not all, of the mementos and other items. On two different occasions, we examined the merchandise in the storage room maintained by the

  9. Gender, diabetes education, and psychosocial factors are associated with persistent poor glycemic control in patients with type 2 diabetes in the Joint Asia Diabetes Evaluation (JADE) program.

    Science.gov (United States)

    Yin, Junmei; Yeung, Roseanne; Luk, Andrea; Tutino, Greg; Zhang, Yuying; Kong, Alice; Chung, Harriet; Wong, Rebecca; Ozaki, Risa; Ma, Ronald; Tsang, Chiu-Chi; Tong, Peter; So, Wingyee; Chan, Juliana

    2016-01-01

    Factors associated with persistent poor glycemic control were explored in patients with type 2 diabetes under the Joint Asia Diabetes Evaluation (JADE) program. Chinese adults enrolled in JADE with HbA1c ≥8% at initial comprehensive assessment (CA1) and repeat assessment were analyzed. The improved group was defined as those with a ≥1% absolute reduction in HbA1c, and the unimproved group was those with patients with HbA1c ≥8% at baseline, 1450 underwent repeat CA. After a median interval of 1.7 years (interquartile range[IQR] 1.1-2.2) between CA1 and CA2, the unimproved group (n = 677) had a mean 0.4% (95% confidence interval [CI] 0.3%, 0.5%) increase in HbA1c compared with a mean 2.8% reduction (95% CI -2.9, -2.6%) in the improved group (n = 773). The unimproved group had a female preponderance with lower education level, and was more likely to be insulin treated. Patients in the improved group received more diabetes education between CAs with improved self-care behaviors, whereas the unimproved group had worsening of health-related quality of life at CA2. Apart from female gender, long disease duration, low educational level, obesity, retinopathy, history of hypoglycemia, and insulin use, lack of education from diabetes nurses between CAs had the strongest association for persistent poor glycemic control. These results highlight the multidimensional nature of glycemic control, and the importance of diabetes education and optimizing diabetes care by considering psychosocial factors. © 2015 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and Wiley Publishing Asia Pty Ltd.

  10. JSPS-NRF-NSFC A3 foresight program seminar. Proceedings of Japan-China joint seminar on atomic and molecular processes in plasma

    International Nuclear Information System (INIS)

    Koike, Fumihiro; Dong Chenzhong; Ding Xiaobin

    2013-02-01

    As one of the activities of JSPS-NRF-NSFC A3 Foresight Program in the field of Plasma Physics (NSFC: No.11261140328), Japan-China Joint Seminar on Atomic and Molecular Processes in Plasma was held on July 30 - August 4, 2012, in Lanzhou, China. The total number of the officially registered participants was 37, in which 14 from Japan, 21 from China, 1 from Germany, and 1 from Ireland. This seminar is the extension of the last three seminars that were held on March 6-11, 2004 in Lanzhou, China, on October 6-12, 2007 in Dunhuang, China, and on October 26-31, 2009 in Xi'an, China. In the nuclear fusion plasma, there are quite a variety of atomic processes such as ionization, excitation, di-electronic recombination, collisional electron transfer, cascade radiation, and cascade Auger decay over the wide range of plasma temperature. The knowledge of those processes is indispensable for the evaluation and improvement of the plasma properties. Especially, in these years, the property of tungsten ions has become a subject of urgent investigations since tungsten has been considered as one of the plasma facing wall materials. Because of the diversity of the subject, it is desirable to investigate them by international collaboration groups. The present seminar may contribute to realize the above stated aim; especially it has given an opportunity for the collaborative workers to illustrate their achievements. The present seminar summarizes the collaborative researches for the last decade and proposes the issues for the future prospect. This issue is the collection of 19 papers presented at the entitled meeting. All the 19 of the presented papers are indexed individually. (J.P.N.)

  11. Joint Operation Planning

    National Research Council Canada - National Science Library

    2006-01-01

    .... It sets forth joint doctrine to govern the joint operation planning activities and performance of the Armed Forces of the United States in joint operations, and provides the joint doctrinal basis...

  12. Expansion joints for LMFBR

    International Nuclear Information System (INIS)

    Dzenus, M.; Hundhausen, W.; Jansing, W.

    1980-01-01

    This discourse recounts efforts put into the SNR-2 project; specifically the development of compensation devices. The various prototypes of these compensation devices are described and the state of the development reviewed. Large Na (sodium)-heat transfer systems require a lot of valuable space if the component lay-out does not include compensation devices. So, in order to condense the spatial requirement as much as possible, expansion joints must be integrated into the pipe system. There are two basic types to suit the purpose: axial expansion joints and angular expansion joints. The expansion joints were developed on the basis of specific design criteria whereby differentiation is made between expansion joints of small and large nominal diameter. Expansion joints for installation in the sodium-filled primary piping are equipped with safety bellows in addition to the actual working bellows. Expansion joints must be designed and mounted in a manner to completely withstand seismic forces. The design must exclude any damage to the bellows during intermittent operations, that is, when sodium is drained the bellows' folds must be completely empty; otherwise residual solidified sodium could destroy the bellows when restarting. The expansion joints must be engineered on the basis of the following design data for the secondary system of the SNR project: working pressure: 16 bar; failure mode pressure: 5 events; failure mode: 5 sec., 28.5 bar, 520 deg. C; working temperature: 520 deg. C; temperature transients: 30 deg. C/sec.; service life: 200,000 h; number of load cycles: 10 4 ; material: 1.4948 or 1.4919; layer thickness of folds: 0.5 mm; angular deflection (DN 800): +3 deg. C or; axial expansion absorption (DN 600): ±80 mm; calculation: ASME class. The bellows' development work is not handled within this scope. The bellows are supplied by leading manufacturers, and warrant highest quality. Multiple bellows were selected on the basis of maximum elasticity - a property

  13. 15 CFR 296.8 - Joint venture agreement.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Joint venture agreement. 296.8 Section... PROGRAM General § 296.8 Joint venture agreement. NIST shall not issue a TIP award to a joint venture and no costs shall be incurred under a TIP project by the joint venture members until such time as a...

  14. Application of Transaction Cost Economics to Capabilities-Based Acquisition: Exploring Single Service vs. Joint Service Programs and Single Systems vs. System-of-Systems

    National Research Council Canada - National Science Library

    Angelis, Diana; Dillard, John; Franck, Raymond; Melese, Francois; Brown, Mary M; Flowe, Robert M

    2008-01-01

    The US Department of Defense (DoD) is in the process of radical transformation -- transformation to a national security strategy predicated on joint Service purchases and complex System-of-Systems (SoS) capabilities...

  15. E-TV

    DEFF Research Database (Denmark)

    Jensen, Ingelise

    2008-01-01

    Materialet er en serie dvd-udgivelser + en lærervejledning med forslag til, hvordan man kan arbejde med filmen, filmscript samt kopiark til elevernes arbejde. Et supplement til den daglige undervisning i engelsk, som gør formidlingen af fremmedsproget kultur levende for eleverne, samtidig med at de...

  16. Festivalifilmid ETV ekraanil

    Index Scriptorium Estoniae

    2007-01-01

    XXI Rahvusvaheline Pärnu filmifestival : Eesti Televisioon näitab 8.-14.07. eriprogrammi, kuhu on valitud filmid "Minu surm, mitte sinu" (Saksamaa-India 2006), "Valgevene õppetund" (Poola-Valgevene 2006), "Beslan - õigus elada" (Venemaa 2006), "Esimene rahu õppetund" (Iisrael 2006), "Õnne vaenlased" (Taani-Afganistan 2006), "Mu tütar on terrorist" (Norra 2006) ja "Lugu kehast" (Iisrael 2006)

  17. ETVS - a process for decentral processing of liquid, pasty and solid organic residues into electrical energy and ash, optionally with hydrosoft high-pressure dewatering, fluidized-bed drying, fluidized-bed gasification and heat-and-power cogeneration using product gas; ETVS - Ein Verfahren zur dezentralen Verwertung von fluessigen, pastoesen und festen biologischen Reststoffen in elektrische Energie und Asche, bedarfsweise mit Hydrosoft-Hochdruckentwaesserung, Wirbelschicht-Trockner, Wirbelschicht-Vergaser und Produktgas-Kraft-Waerme-Kopplung

    Energy Technology Data Exchange (ETDEWEB)

    Eder, C.; Eder, G. [Christian Eder Technology, Neunkirchen (Germany); Wied, E. [Bisanz GmbH, Saarbruecken (Germany)

    1999-07-01

    By means of the ETVS process, predominantly liquid organic residues can be converted into electrical energy and mineral ash decentrally, i.e. where they accrue. The process is exemplified with reference to sewage sludge. Sludge containing at least about 4 % dry residue is dewatered to the highest dry substance content possible. The obtained filter cakes are indirectly dried in a fluidized-bed drier using internal process waste heat. Then the organic sewage sludge constituents are gasified in an atmospheric fluidized bed system. The cleaned product gas is used to generate power in a cogeneration power plant, meeting the sewage treatment plant's in-house power demand. The ETVS process is self-sufficient in terms of thermal energy requirement from an initial dry substance content of the filter cake > 40 %. Incineration is a means of disposing of sewage sludge in accordance with the boundary conditions for sewage sludge disposal from 2005, laid down in the technical code on municipal waste. Combining the ETVS process with modern biological treatment stages makes for a substantial cut in the construction and operating cost of sewage treatment plants. (orig.) [German] Mit dem ETVS-Verfahren koennen ueberwiegend fluessige biologische Reststoffe dezentral, d.h. an der Anfallstelle in eigennutzbare elektrische Energie und mineralische Asche umgewandelt werden. Das Verfahren wird am Klaerschlamm beispielhaft dargestellt. Der Klaerschlamm wird ab einem Trockensubstanzgehalt von ca. 4%TR auf moeglichst hohe Trockensubstanzgehalte entwaessert und die dabei erzeugten Filterkuchen mit internen Prozessabwaermen in einem Wirbelschichttrockner indirekt getrocknet. Die organischen Bestandteile des Klaerschlammes werden anschliessend in einer ebenfalls atmosphaerischen Wirbelschichtanlage vergast. Der mit dem gereinigten Produktgas in einer KWK-Anlage erzeugte Strom wird zur Deckung des Eigenbedarfs der Klaeranlage verwandt. Durch die Veraschung liefert das ab einem

  18. Joint and Coordinated Calls for Science and Technology Programs between Ukraine and the European Commission as a Potential Tool for Harmonization of the EU-Ukraine Priorities

    Directory of Open Access Journals (Sweden)

    M. Gorohovatska

    2013-07-01

    Full Text Available Results of scientific cooperation between European countries, including Ukraine, within the Seventh Framework Programme for Research and Technological Development are reviewed. Terms of preparation of joint and coordinated EUUkraine calls within the Framework Programme «Horizon 2020» are discussed; terms and conditions of participation in these calls are determined.

  19. Joint Instability and Osteoarthritis

    Directory of Open Access Journals (Sweden)

    Darryl Blalock

    2015-01-01

    Full Text Available Joint instability creates a clinical and economic burden in the health care system. Injuries and disorders that directly damage the joint structure or lead to joint instability are highly associated with osteoarthritis (OA. Thus, understanding the physiology of joint stability and the mechanisms of joint instability-induced OA is of clinical significance. The first section of this review discusses the structure and function of major joint tissues, including periarticular muscles, which play a significant role in joint stability. Because the knee, ankle, and shoulder joints demonstrate a high incidence of ligament injury and joint instability, the second section summarizes the mechanisms of ligament injury-associated joint instability of these joints. The final section highlights the recent advances in the understanding of the mechanical and biological mechanisms of joint instability-induced OA. These advances may lead to new opportunities for clinical intervention in the prevention and early treatment of OA.

  20. Joint instability and osteoarthritis.

    Science.gov (United States)

    Blalock, Darryl; Miller, Andrew; Tilley, Michael; Wang, Jinxi

    2015-01-01

    Joint instability creates a clinical and economic burden in the health care system. Injuries and disorders that directly damage the joint structure or lead to joint instability are highly associated with osteoarthritis (OA). Thus, understanding the physiology of joint stability and the mechanisms of joint instability-induced OA is of clinical significance. The first section of this review discusses the structure and function of major joint tissues, including periarticular muscles, which play a significant role in joint stability. Because the knee, ankle, and shoulder joints demonstrate a high incidence of ligament injury and joint instability, the second section summarizes the mechanisms of ligament injury-associated joint instability of these joints. The final section highlights the recent advances in the understanding of the mechanical and biological mechanisms of joint instability-induced OA. These advances may lead to new opportunities for clinical intervention in the prevention and early treatment of OA.

  1. Electrothermal vaporisation ICP-mass spectrometry (ETV-ICP-MS) for the determination and speciation of trace elements in solid samples - A review of real-life applications from the author's lab

    Energy Technology Data Exchange (ETDEWEB)

    Vanhaecke, Frank; Resano, Martin; Moens, Luc [Laboratory of Analytical Chemistry, Ghent University, Institute for Nuclear Sciences, Proeftuinstraat 86, 9000 Ghent (Belgium)

    2002-09-01

    The use of electrothermal vaporisation (ETV) from a graphite furnace as a means of sample introduction in inductively coupled plasma mass spectrometry (ICP-MS) permits the direct analysis of solid samples. A multi-step furnace temperature programme is used to separate the vaporisation of the target element(s) and of the matrix components from one another. Sometimes, a chemical modifier is used to enable a higher thermal pre-treatment temperature, by avoiding premature analyte losses (stabilisation) or promoting the selective volatilisation of matrix components. In almost all instances, accurate results can be obtained via external calibration or single standard addition using an aqueous standard solution. Absolute limits of detection are typically 1 pg, which corresponds to 1 ng/g for a typical sample mass of 1 mg. Real-life applications carried out in the author's lab are used to illustrate the utility of this approach. These applications aim at trace element determination in industrial and environmental materials. The industrial materials analysed include different types of plastics - Carilon, polyethylene, poly(ethyleneterephtalate) and polyamide - and photo- and thermographic materials. As samples from environmental origin, plant material, animal tissue and sediments were investigated. Some applications aimed at a multi-element determination, while in other, the content of a single, but often challenging, element (e.g., Si or S) had to be measured. ETV-ICP-MS was also used in elemental speciation studies. Separation of Se-containing proteins was accomplished using polyacrylamide gel electrophoresis (PAGE). Subsequent quantification of the Se content in the protein spots was carried out using ETV-ICP-MS. As the volatilisation of methylmercury and inorganic mercury could be separated from one another with respect to time, no chromatographic or electrophoretic separation procedure was required, but ETV-ICP-MS as such sufficed for Hg speciation in fish tissue

  2. Joint Ventures: A New Agenda for Education.

    Science.gov (United States)

    Griffin, Dean

    1989-01-01

    The author states that vocational education can join in partnerships with industry, labor, and government to contribute to economic development. Examples of current programs are included. The "joint venture" concept is explained and ideas for forming joint ventures are shared. (CH)

  3. 95. German Roentgen congress and 7. joint congress of the DRG and OeRG. Program with abstracts; 95. Deutscher Roentgenkongress und 7. Gemeinsamer Kongress von DRG und OeRG. Vollstaendiges Programm mit Abstracts

    Energy Technology Data Exchange (ETDEWEB)

    Diederich, Stefan; Lammer, Johannes (eds.)

    2014-05-15

    The volume contains the program and the abstracts of the 95th German Roentgen congress and the 7th joint congress of the DRG and OeRG. The radiological focal points of the congress were thorax radiology (pneumology: lung fibrosis, emphysema); oncological radiology: skeletal carcinoma, lung carcinoma, kidneys, lung metastases, primary liver carcinoma, liver metastases. Further topics included radiology in hospitals and medical centers, tele-radiology, ambulant health care, legal issues, financial accounting and management issues. Several courses an specific radiological issues and radiological techniques were offered, including radiation protection and legal aspects.

  4. Cerebrospinal fluid (CSF) shunting and ventriculocisternostomy (ETV) in 400 pediatric patients. Shifts in understanding, diagnostics, case-mix, and surgical management during half a century.

    Science.gov (United States)

    Paulsen, A Henriette; Due-Tønnessen, Bernt J; Lundar, Tryggve; Lindegaard, Karl-Fredrik

    2017-02-01

    To characterize shifts from the 1960s to the first decade in the 21st century as to diagnostics, case-mix, and surgical management of pediatric patients undergoing permanent CSF diversion procedures. One hundred and thirty-four patients below 15 years of age were the first time treated with CSF shunt or ETV for hydrocephalus or idiopathic intracranial hypertension (IIH) in 2009-2013. This represents our current practice. Our previously reported cohorts of shunted children 1967-1970 (n = 128) and 1985-1988 (n = 138) served as backgrounds for comparison. In the 1960s, ventriculography and head circumference measurements were the main diagnostic tools; ventriculoatrial shunt was the preferred procedure (94 %), neural tube defect (NTD) was the leading etiology (33 %), and overall 2-year survival rate was 76 % (non-tumor survival 84 %). In the 1980s, computerized tomography (CT) was the preferred diagnostic imaging tool; ventriculoperitoneal shunt (VPS) had become standard (91 %), the proportion of NTD children declined to 17 %, and the 2-year survival rate was 91 % (non-tumor survival 95 %). Hydrocephalus caused by intracranial hemorrhage had, on the other hand, increased from 7 to 19 %. In the years 2009-2013, when MRI and endoscopic third ventriculocisternostomy (ETV) were matured technologies, 73 % underwent VPS, and 23 % ETV as their initial surgical procedure. The most prevalent etiology was CNS tumor (31 %). The proportion of NTD patients was yet again halved to 8 %, while intracranial hemorrhage was also reduced to 12 %. In this last period, six children were treated with VPS for Idiopathic Intracranial Hypertension (IIH) due to unsatisfactory response to medical treatment. They all had headache, papilledema, and visual disturbances and responded favorably to treatment. The 2 years of survival was 92 % (non-tumor survival 99 %). In contrast to the previous periods, there was no early shunt related mortality (2 years). Aqueductal stenosis

  5. International joint ventures

    DEFF Research Database (Denmark)

    Sørensen, Karsten Engsig

    2001-01-01

    The article analysis problems connected with corporate joint ventures. Among others the possible conflicts between the joint venture agreement and the statutes of the companies is examined, as well as certain problems connected to the fact that the joint venture partners have created commen control...... over their joint company....

  6. Fiscal 1999 research report. Basic research for promotion of joint implementation programs (Research on energy saving plan for NORSI Refinery); 1999 nendo NORSI seiyusho sho energy keikaku chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This is a feasibility study desired to connect to a joint implementation program in the future, which plans to modify the oil refining system now in existence at the NORSI Refinery in the Russian Federation. The modification plan for energy efficiency improvement consists of (1) the reconstruction of the heat exchanger network, addition of three high-efficiency heating furnaces, and the introduction of stripping steam into the pre-distillation tower for the atmospheric/vacuum distillation system, (2) the addition of two combined heat exchangers, replacement of the reboiler with a steam reboiler, and the use of reflux line in the deethanization tower for the reforming section of the catalytic reforming unit, and (3) the addition of combined heat exchangers and the installation of two high-efficiency heater furnaces for the hydrodesulfurization unit for kerosene and light oil. The plan requires 40,470,000 dollars, and will save 48,000 tons/year in terms of oil and reduce CO2 emissions by 120,000 tons/year. No settlement has been reached, however, about financing, agreement to cost performance, or apportioning of the amount of reduction in CO2 emissions to the parties involved in case of transfer under a joint implementation program. It is desired that these problems will be solved for the promotion of the project. (NEDO)

  7. Sikap Bangladesh Dalam Menanggapi Program Unhcr €œUnited Nations Joint Initiative€ Terhadap Penanganan Pengungsi Rohingya (Periode 2006-2011)

    OpenAIRE

    Olivia, Yessy; ", Mery

    2014-01-01

    This research explains Bangladesh€™s response about UNHCR€™s €œUnited Nations Joint Initiative€ in handling Rohingya refugees in Bangladesh. Bangladesh is now home to 29.016 Rohingyas. The refugees has caused social and economic problems for Bangladeshi goverment over 33 years. UNJI was proposed by UNHCR to help Rohingyas ang Bangladeshis.The research applies qualitative methods, and case study in this research the data collected through library research, literature studies, official documen...

  8. 15 CFR 296.7 - Joint venture registration.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Joint venture registration. 296.7 Section 296.7 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL... PROGRAM General § 296.7 Joint venture registration. Joint ventures selected for assistance under the...

  9. The impact of TEL-AML1 (ETV6-RUNX1) expression in precursor B cells and implications for leukaemia using three different genome-wide screening methods

    International Nuclear Information System (INIS)

    Linka, Y; Ginzel, S; Krüger, M; Novosel, A; Gombert, M; Kremmer, E; Harbott, J; Thiele, R; Borkhardt, A; Landgraf, P

    2013-01-01

    The reciprocal translocation t(12;21)(p13;q22), the most common structural genomic alteration in B-cell precursor acute lymphoblastic leukaemia in children, results in a chimeric transcription factor TEL-AML1 (ETV6-RUNX1). We identified directly and indirectly regulated target genes utilizing an inducible TEL-AML1 system derived from the murine pro B-cell line BA/F3 and a monoclonal antibody directed against TEL-AML1. By integration of promoter binding identified with chromatin immunoprecipitation (ChIP)-on-chip, gene expression and protein output through microarray technology and stable labelling of amino acids in cell culture, we identified 217 directly and 118 indirectly regulated targets of the TEL-AML1 fusion protein. Directly, but not indirectly, regulated promoters were enriched in AML1-binding sites. The majority of promoter regions were specific for the fusion protein and not bound by native AML1 or TEL. Comparison with gene expression profiles from TEL-AML1-positive patients identified 56 concordantly misregulated genes with negative effects on proliferation and cellular transport mechanisms and positive effects on cellular migration, and stress responses including immunological responses. In summary, this work for the first time gives a comprehensive insight into how TEL-AML1 expression may directly and indirectly contribute to alter cells to become prone for leukemic transformation

  10. It Is a Brave New World: Alternative Payment Models and Value Creation in Total Joint Arthroplasty: Creating Value for TJR, Quality and Cost-Effectiveness Programs.

    Science.gov (United States)

    Chen, Kevin K; Harty, Jonathan H; Bosco, Joseph A

    2017-06-01

    The increasing cost of our country's healthcare is not sustainable. To address this crisis, the federal government is transiting healthcare reimbursement from the traditional volume-based system to a value-based system. As such, increasing healthcare value has become an essential point of discussion for all healthcare stakeholders. The purpose of this study is to discuss the importance of healthcare value as a means to achieve this goal of value-based medicine and 3 methods to create value in total joint arthroplasty. These methods are to: (1) improve outcomes greater than the increased costs to achieve this improvement, (2) decrease costs without affecting outcomes, and (3) decrease costs while simultaneously improving outcomes. Following these guidelines will help practitioners thrive in a bundled care environment. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. Medicare Program; Advancing Care Coordination Through Episode Payment Models (EPMs); Cardiac Rehabilitation Incentive Payment Model; and Changes to the Comprehensive Care for Joint Replacement Model (CJR). Final rule.

    Science.gov (United States)

    2017-01-03

    This final rule implements three new Medicare Parts A and B episode payment models, a Cardiac Rehabilitation (CR) Incentive Payment model and modifications to the existing Comprehensive Care for Joint Replacement model under section 1115A of the Social Security Act. Acute care hospitals in certain selected geographic areas will participate in retrospective episode payment models targeting care for Medicare fee-forservice beneficiaries receiving services during acute myocardial infarction, coronary artery bypass graft, and surgical hip/femur fracture treatment episodes. All related care within 90 days of hospital discharge will be included in the episode of care. We believe these models will further our goals of improving the efficiency and quality of care for Medicare beneficiaries receiving care for these common clinical conditions and procedures.

  12. Program and Abstracts of the ninth Joint Uzbek-Korea Symposium Nanoscience: Problems and Prospects on Quantum Functional Materials and Devices

    International Nuclear Information System (INIS)

    Zakhidov, E.A.; Kang, T.W.; Mamatkulov, Sh.; Kokhkharov, A.M.; Cho Hak Dong

    2010-11-01

    The Ninth Joint Uzbek-Korea Symposium on Quantum Functional Materials and Devices was held on November 2-5, 2010 in Tashkent, Uzbekistan. The purpose of the Symposium is to provide a forum for Uzbekistan and Korean scientists to get together and discuss recent progress and future trends in the rapidly advancing nanoscience and nanotechnology. The symposium will promote an exchange of scientific information and a mutual collaboration. Symposium activities include in-depth coverage on materials grows, physics, characterization, device fabrication and application. The main scientific topics of the symposium: Synthesis of nanomaterials, nanocomposites and nanostructures; Structural, electrical and optical properties; New concepts of devices and related phenomena; Theoretical aspects of nanosciense. (eds.)

  13. Life Estimation of Hip Joint Prosthesis

    Science.gov (United States)

    Desai, C.; Hirani, H.; Chawla, A.

    2015-07-01

    Hip joint is one of the largest weight-bearing structures in the human body. In the event of a failure of the natural hip joint, it is replaced with an artificial hip joint, known as hip joint prosthesis. The design of hip joint prosthesis must be such so as to resist fatigue failure of hip joint stem as well as bone cement, and minimize wear caused by sliding present between its head and socket. In the present paper an attempt is made to consider both fatigue and wear effects simultaneously in estimating functional-life of the hip joint prosthesis. The finite element modeling of hip joint prosthesis using HyperMesh™ (version 9) has been reported. The static analysis (load due to the dead weight of the body) and dynamic analysis (load due to walking cycle) have been described. Fatigue life is estimated by using the S-N curve of individual materials. To account for progressive wear of hip joint prosthesis, Archard's wear law, modifications in socket geometry and dynamic analysis have been used in a sequential manner. Using such sequential programming reduction in peak stress has been observed with increase in wear. Finally life is estimated on the basis of socket wear.

  14. Joint Replacement (Finger and Wrist Joints)

    Science.gov (United States)

    ... All Topics A-Z Videos Infographics Symptom Picker Anatomy Bones Joints Muscles Nerves Vessels Tendons About Hand Surgery What is a Hand Surgeon? What is a Hand Therapist? Media Find a Hand Surgeon Home Anatomy Joint Replacement Email to a friend * required fields ...

  15. First experience with a new biomedical engineering program in Slovenia established following the TEMPUS IV CRH-BME joint project guidelines.

    Science.gov (United States)

    Jarm, Tomaz; Miklavcic, Damijan

    2014-01-01

    A new study program of biomedical engineering was recently established at Faculty of Electrical Engineering, University of Ljubljana, Slovenia. It is based on the long-lasting tradition of education in the field of BME at the host institution and is built on the BME areas in which the research groups of the Faculty of Electrical Engineering have been traditionally successful. The program was prepared in accordance with the recommendations of the TEMPUS IV CRH-BME Project consortium.

  16. Experience of joint use NDA instruments between Japan and IAEA in inspection fields

    International Nuclear Information System (INIS)

    Yoshii, Hiroshi; Aoki, Minoru; Shimizu, Toku

    1997-01-01

    In order to implement more effective and efficient safeguards scheme in Japan, Japan and IAEA established joint use program of NDA instruments which was commenced in 1989 from LEU fuel fabrication facilities. The joint use program was proposed by Science and Technology Agency (STA) in the 10th (1989) Joint Japan and IAEA Committee, and it was agreed. Subsequently, Japan and IAEA established working group of the joint use program, whose prepared necessary joint use procedures. Currently, the joint use program has been expanding to almost facilities in domestic, and has been contributing reduce the facility operator's burden for the for inspection activities. (author)

  17. Hip joint injection

    Science.gov (United States)

    ... medicine into the joint. The provider uses a real-time x-ray (fluoroscopy) to see where to place ... Wakefield RJ. Arthrocentesis and injection of joints and soft tissue. In: Firestein GS, Budd RC, Gabriel SE, ...

  18. Sacroiliac joint pain - aftercare

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/patientinstructions/000610.htm Sacroiliac joint pain - aftercare To use the sharing features on this page, please enable JavaScript. The sacroiliac joint (SIJ) is a term used to describe ...

  19. Reliability of Tubular Joints

    DEFF Research Database (Denmark)

    Sørensen, John Dalsgaard; Thoft-Christensen, Palle

    In this paper the preliminary results obtained by tests on tubular joints are presented. The joints are T-joints and the loading is static. It is the intention in continuation of these tests to perform tests on other types of joints (e.g. Y-joints) and also with dynamic loading. The purpose...... of the test is partly to obtain empirical data for the ultimate load-carrying capacity of tubular T-joints and partly to obtain some experience in performing tests with tubular joints. It is well known that tubular joints are usually designed in offshore engineering on the basis of empirical formulas obtained...... by experimental test results. Therefore, there is a need for performing experimental tests in this area....

  20. Hip joint replacement - slideshow

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/presentations/100006.htm Hip joint replacement - series—Normal anatomy To use the ... to slide 5 out of 5 Overview The hip joint is made up of two major parts: ...

  1. Design of mechanical joints

    CERN Document Server

    Blake, Alexander

    2018-01-01

    A cornerstone publication that covers the basic principles and practical considerations of design methodology for joints held by rivets, bolts, weld seams, and adhesive materials, Design of Mechanical Joints gives engineers the practical results and formulas they need for the preliminary design of mechanical joints, combining the essential topics of joint mechanics...strength of materials...and fracture control to provide a complete treatment of problems pertinent to the field of mechanical connections.

  2. Managing Joint Production Motivation

    DEFF Research Database (Denmark)

    Lindenberg, Siegwart; Foss, Nicolai Juul

    2011-01-01

    We contribute to the microfoundations of organizational performance by proffering the construct of joint production motivation. Under such motivational conditions individuals see themselves as part of a joint endeavor, each with his or her own roles and responsibilities; generate shared...... representations of actions and tasks; cognitively coordinate cooperation; and choose their own behaviors in terms of joint goals. Using goal-framing theory, we explain how motivation for joint production can be managed by cognitive/symbolic management and organizational design....

  3. RSRM Nozzle-to-Case Joint J-leg Development

    Science.gov (United States)

    Albrechtsen, Kevin U.; Eddy, Norman F.; Ewing, Mark E.; McGuire, John R.

    2003-01-01

    Since the beginning of the Space Shuttle Reusable Solid Rocket Motor (RSRM) program, nozzle-to-case joint polysulfide adhesive gas paths have occurred on several flight motors. These gas paths have allowed hot motor gases to reach the wiper O-ring. Even though these motors continue to fly safely with this condition, a desire was to reduce such occurrences. The RSRM currently uses a J-leg joint configuration on case field joints and igniter inner and outer joints. The J-leg joint configuration has been successfully demonstrated on numerous RSRM flight and static test motors, eliminating hot gas intrusion to the critical O-ring seals on these joints. Using the proven technology demonstrated on the case field joints and igniter joints, a nozzle-to-case joint J-leg design was developed for implementation on RSRM flight motors. This configuration provides an interference fit with nozzle fixed housing phenolics at assembly, with a series of pressurization gaps incorporated outboard of the joint mating surface to aid in joint pressurization and to eliminate any circumferential flow in this region. The joint insulation is bonded to the nozzle phenolics using the same pressure sensitive adhesive used in the case field joints and igniter joints. An enhancement to the nozzle-to-case joint J-leg configuration is the implementation of a carbon rope thermal barrier. The thermal barrier is located downstream of the joint bondline and is positioned within the joint in a manner where any hot gas intrusion into the joint passes through the thermal barrier, reducing gas temperatures to a level that would not affect O-rings downstream of the thermal barrier. This paper discusses the processes used in reaching a final nozzle-to-case joint J-leg design, provides structural and thermal results in support of the design, and identifies fabrication techniques and demonstrations used in arriving at the final configuration.

  4. Solid phase extraction for analysis of biogenic carbonates by electrothermal vaporization inductively coupled plasma mass spectrometry (ETV-ICP-MS): an investigation of rare earth element signatures in otolith microchemistry

    International Nuclear Information System (INIS)

    Arslan, Zikri; Paulson, Anthony J.

    2003-01-01

    Uptake of trace elements into fish otoliths is governed by several factors such as life histories and environment in addition to stock and species differences. In an attempt to elucidate the elemental signatures of rare earth elements (REEs) in otoliths, a solid phase extraction (SPE) protocol was used in combination with electrothermal vaporization (ETV) as a sample introduction procedure for the determinations by inductively coupled plasma quadrupole mass spectrometry (ICP-MS). Effects of various parameters, such as carrier gas flow rate, atomization temperature and chemical modification, were examined for optimization of the conditions by ETV-ICP-MS. Atomization was achieved at 2800 deg. C. Lower temperatures (i.e. 2600 deg. C) resulted in severe memory problems due to incomplete atomization. Palladium was used as a chemical modifier. It was found that an increase in Pd concentration up to 0.5 μg in the injection volume (70 μl) led up to four-fold enhancement in the integrated signals. This phenomenon is attributed to the carrier effect of Pd rather than the stabilization since no significant losses were observed for high temperature drying around 700 deg. C even in the absence of Pd. Preconcentration was performed on-line at pH 5 by using a mini-column of Toyopearl AF-Chelate 650M chelating resin, which also eliminated the calcium matrix of otolith solutions. After preconcentration of 6.4 ml of solution, the concentrate was collected in 0.65 ml of 0.5% (v/v) HNO 3 in autosampler cups, and then analyzed by ETV-ICP-MS. The method was validated with the analysis of a fish otolith certified reference material (CRM) of emperor snapper, and then applied to samples. Results obtained from otoliths of fish captured in the same habitat indicated that otolith rare earth element concentrations are more dependent on environmental conditions of the habitat than on species differences

  5. Report of the Defense Science Board/Air Force Scientific Advisory Board Joint Task Force on Acquisition of National Security Space Programs

    Science.gov (United States)

    2003-05-01

    space requires both contractors---at least until sustainable performance is demonstrated • EELV program has occurred in highly cost constrained...both contractors • Take necessary actions to assure both contractors remain viable---at least until sustainable performance is demonstrated

  6. 2007 Joint Chemical Biological, Radiological and Nuclear (CBRN) Conference and Exhibition - Combating Weapons of Mass Destruction

    Science.gov (United States)

    2007-06-27

    Selected CB Defense Systems SHAPESENSE Joint Warning and Reporting Network JSLIST CB Protected Shelter Joint Vaccine Acquisition Program Joint Effects...military can operate in any environment, unconstrained by chemical or biological weapons. 21 SHIELD SUSTAIN Selected CB Defense Systems SHAPESENSE Joint...28070625_JCBRN_Conference_Reeves UNCLASSIFIED Decontamination Vision Strippable Barriers Self-Decontaminating Fabrics/Coatings Reduce Logistics Burden

  7. Rapid determination of 90Sr by electrothermal vaporization-inductively coupled plasma mass spectrometry (ETV-ICP-MS)

    International Nuclear Information System (INIS)

    Berryman, N.; Probst, T.

    1997-01-01

    A two-step temperature program has been developed to determine 90 Sr in highly active samples in the presence of Zr. In a first step, Sr is volatilized at 2400 C using argon as a carrier gas, while Zr is completely retained in the graphite tube. It is removed in a second step by adding 0.1% CHF 3 to the argon carrier gas and increasing the temperature to 2650 C. Even a 100 fold excess of Zr has no detrimental effects on the determination of 90 Sr. The detection limit is 2 pg/ml (10 Bq/ml) without using a modifier. (orig.)

  8. Russian RERTR program as a part of Joint US DOE-RF MINATOM collaboration on elimination of the threat connected to the use of HEU in research reactors

    International Nuclear Information System (INIS)

    Arkhangelsky, N.

    2002-01-01

    The Russian RERTR Program started at the end of 70's, the final goal of the program is to eliminate supplies of HEU in fuel elements and assemblies for foreign research reactors that were designed according to Russian projects. Basic directions of the work include: completion of the development of the fuel elements and assemblies on a basis of uranium dioxide; development of the fuel on a basis of U-Mo alloy; and development of pin type fuel elements. Fuel assemblies of WWR-M2 type with LEU were developed and qualified for using in foreign research reactors that use such type of fuel assemblies. These assemblies are ready for the supplying several operating foreign research reactors. There are more than 20 sites in Eastern European countries, former Soviet republics and another countries that have big amount of Russian origin HEU in fresh and spent fuel. The problem of the shipment of SNF from sites of research reactors is also very important for domestic Russian research reactors. More than ten years from its beginning the Russian RERTR program developed practically independently from the international RERTR program and only at the begin of 90's the Russian specialists started to contact with foreign scientists and the exchange of the scientific information has become more intensive. In September 1994, representatives of Minatom and DOE signed a protocol of intent to reduce an enrichment of uranium in research reactors. The main aspects of collaboration involve: Several domestic Russian research reactors such as WWR-M, IR-8 and others were investigated from the point of view of possibility of reducing of enrichment; financial support of the program from US DOE which is insufficient. The important part of international collaboration is the import of Russian origin spent and fresh fuel of research reactors to Russia. In August 2002 an impressive result of the Russian-American collaboration with support of IAEA and with the help and assistance of Yugoslavian side was

  9. Programming

    International Nuclear Information System (INIS)

    Jackson, M.A.

    1982-01-01

    The programmer's task is often taken to be the construction of algorithms, expressed in hierarchical structures of procedures: this view underlies the majority of traditional programming languages, such as Fortran. A different view is appropriate to a wide class of problem, perhaps including some problems in High Energy Physics. The programmer's task is regarded as having three main stages: first, an explicit model is constructed of the reality with which the program is concerned; second, this model is elaborated to produce the required program outputs; third, the resulting program is transformed to run efficiently in the execution environment. The first two stages deal in network structures of sequential processes; only the third is concerned with procedure hierarchies. (orig.)

  10. Programming

    OpenAIRE

    Jackson, M A

    1982-01-01

    The programmer's task is often taken to be the construction of algorithms, expressed in hierarchical structures of procedures: this view underlies the majority of traditional programming languages, such as Fortran. A different view is appropriate to a wide class of problem, perhaps including some problems in High Energy Physics. The programmer's task is regarded as having three main stages: first, an explicit model is constructed of the reality with which the program is concerned; second, thi...

  11. PROGRAMA PARA LA VERIFICACIN DE LA TECNOLOGIA AMBIENTAL/ENVIRONMENTAL TECHNOLOGY VERIFICATION PROGRAM (ETV) (EPA/600/F-98/015A)

    Science.gov (United States)

    A travs de su historia, la Agencia de Proteccin del Medio Ambiente estadounidense (U.S. Environmental Protection Agency, EPA) ha evaluado distintas tecnologas para determinar su efectividad en el monitoreo, la prevencin, el control, y la limpieza de la contaminacin ambiental. Sin...

  12. 26th May 2011 -Delegate to CERN Open Council sessions and European Commission Head of Unit for Joint Programming European Research Area, DG Research and Innovation R. Lečbychová visiting the CERN Control Centre with M. Pojer, accompanied by CERN S. Stavrev.

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    26th May 2011 -Delegate to CERN Open Council sessions and European Commission Head of Unit for Joint Programming European Research Area, DG Research and Innovation R. Lečbychová visiting the CERN Control Centre with M. Pojer, accompanied by CERN S. Stavrev.

  13. Hydrocolonotherapy ankle joints after injuries

    Directory of Open Access Journals (Sweden)

    Volodymyr Muchin

    2016-02-01

    Full Text Available Purpose: to improve efficiency of gydrokinesitherapy by means of specially designed devices and monolasts for patients after ankle joint injuries. Material & Methods: there are pedagogical methods, clinical and radiological methods, anthropometric measurements and goniometry were used. Results: the author's technique of hydrokinesitherapy with application hydrokinesimechanotherapy device in the program of physical rehabilitation which provides optimum conditions for the recovery process was developed. Conclusions: the specially designed hydrokinesomechanotherapeutic device and monolasts are allow strictly controlled movement in all planes of the ankle joint, which contributes to the acceleration of the recovery; the conducted anthropometric and goniometric studies were indicate more rapid elimination of edema, increase movement amplitude, carries opposition to the development of contractures and muscle atrophy.

  14. Mechanics of Suture Joints

    Science.gov (United States)

    Li, Yaning; Song, Juha; Ortiz, Christine; Boyce, Mary; Ortiz Group/DMSE/MIT Team; Boyce Group/ME/MIT Team

    2011-03-01

    Biological sutures are joints which connect two stiff skeletal or skeletal-like components. These joints possess a wavy geometry with a thin organic layer providing adhesion. Examples of biological sutures include mammalian skulls, the pelvic assembly of the armored fish Gasterosteus aculeatus (the three-spined stickleback), and the suture joints in the shell of the red-eared slider turtle. Biological sutures allow for movement and compliance, control stress concentrations, transmit loads, reduce fatigue stress and absorb energy. In this investigation, the mechanics of the role of suture geometry in providing a naturally optimized joint is explored. In particular, analytical and numerical micromechanical models of the suture joint are constructed. The anisotropic mechanical stiffness and strength are studied as a function of suture wavelength, amplitude and the material properties of the skeletal and organic components, revealing key insights into the optimized nature of these ubiquitous natural joints.

  15. 2010 Joint United States-Canadian Program to explore the limits of the Extended Continental Shelf aboard U.S. Coast Guard Cutter Healy--Cruise HLY1002

    Science.gov (United States)

    Edwards, Brian D.; Childs, Jonathan R.; Triezenberg, Peter J.; Danforth, William W.; Gibbons, Helen

    2013-01-01

    In August and September 2010, the U.S. Geological Survey, in cooperation with Natural Resources Canada, Geological Survey of Canada, conducted bathymetric and geophysical surveys in the Beaufort Sea and eastern Arctic Ocean aboard the U.S. Coast Guard Cutter Healy. The principal objective of this mission to the high Arctic was to acquire data in support of a delineation of the outer limits of the U.S. and Canadian Extended Continental Shelf in the Arctic Ocean, in accordance with the provisions of Article 76 of the United Nations Convention on the Law of the Sea. The Healy was accompanied by the Canadian Coast Guard icebreaker Louis S. St-Laurent. The scientific parties on board the two vessels consisted principally of staff from the U.S. Geological Survey (Healy), and the Geological Survey of Canada and the Canadian Hydrographic Service (Louis). The crew also included marine-mammal observers, Native-community observers, ice observers, and biologists conducting research of opportunity in the Arctic Ocean. Despite interruptions necessitated by three medical emergencies, the joint survey proved largely successful. The Healy collected 7,201 trackline-kilometers of swath (multibeam) bathymetry (47,663 square kilometers) and CHIRP subbottom data, with accompanying marine gravity measurements, and expendable bathythermograph data. The Louis acquired 3,673 trackline-kilometers of multichannel seismic (airgun) deep-penetration reflection data along 25 continuous profiles, as well as 34 sonobuoy refraction stations and 9,500 trackline-kilometers of single-beam bathymetry. The coordinated efforts of the two vessels resulted in seismic-reflection-profile data that were of much higher quality and continuity than if the data had been acquired with a single vessel alone. The equipment-failure rate of the seismic equipment aboard the Louis was greatly reduced when the Healy led as the ice breaker. When ice conditions proved too severe to deploy the seismic system, the Louis led

  16. Expansion joints for LMFBR

    Energy Technology Data Exchange (ETDEWEB)

    Dzenus, M.; Hundhausen, W.; Jansing, W.

    1979-10-15

    This discourse recounts efforts put into the SNR-2 project; specifically the development of compensation devices. The various prototypes of these compensation devices are described and the state of development reviewed. The expansion joints were developed on the basis of specific design criteria whereby differentiation is made between expansion joints of small and large nominal diameter. Expansion joints for installation in the sodium-filled primary piping are equipped with safety bellows in addition to the actual working bellows.

  17. Finite element analysis of elasto-plastic tee joints

    International Nuclear Information System (INIS)

    Powell, G.H.

    1974-09-01

    The theory and computational procedures used in the computer program B169TJ/EP for the analysis of elasto-plastic tee joints are described, and detailed user's guide is presented. The program is particularly applicable to joints conforming to the ANSI B16.9 Manufacturing Standard, but can also be applied to other joint geometries. The joint may be loaded by internal pressure and by arbitrary combinations of applied forces and moments at the ends of the branch and run pipes, and the loading sequence may be arbitrary. The joint material is assumed to yield according to the von Mises criterion, and to exhibit either linear kinematic hardening or nonlinear isotropic hardening after yield. The program makes use of the finite element and mesh generation procedures previously applied in the elastic stress analysis program B16.9TJ/ SA, with minor modifications. (U.S.)

  18. Society for Health Psychology (APA Division 38) and Society of Behavioral Medicine joint position statement on the Medicare Diabetes Prevention Program.

    Science.gov (United States)

    Fitzpatrick, Stephanie L; Wilson, Dawn K; Pagoto, Sherry L

    2017-06-01

    Beginning in January 2018, the Centers for Medicare and Medicaid Services (CMS) plans to cover the Diabetes Prevention Program (DPP), also referred to as Medicare DPP. The American Psychological Association Society for Health Psychology (SfHP) and the Society for Behavioral Medicine (SBM) reviewed the proposed plan. SfHP and SBM are in support of the CMS decision to cover DPP for Medicare beneficiaries but have a significant concern that aspects of the proposal will limit the public health impact. Concerns include the emphasis on weight outcomes to determine continued coverage and the lack of details regarding requirements for coaches. SfHP and SBM are in strong support of modifications to the proposal that would remove the minimum weight loss stipulation to determine coverage and to specify type and qualifications of "coaches."

  19. Surgical Technical Evidence Review for Elective Total Joint Replacement Conducted for the AHRQ Safety Program for Improving Surgical Care and Recovery

    Science.gov (United States)

    Siletz, Anaar E.; Singer, Emily S.; Faltermeier, Claire; Hu, Q. Lina; Ko, Clifford Y.; Golladay, Gregory J.; Kates, Stephen L.; Wick, Elizabeth C.; Maggard-Gibbons, Melinda

    2018-01-01

    Background: Use of enhanced recovery pathways (ERPs) can improve patient outcomes, yet national implementation of these pathways remains low. The Agency for Healthcare Research and Quality (AHRQ; funder), the American College of Surgeons, and the Johns Hopkins Medicine Armstrong Institute for Patent Safety and Quality have developed the Safety Program for Improving Surgical Care and Recovery—a national effort to catalyze implementation of practices to improve perioperative care and enhance recovery of surgical patients. This review synthesizes evidence that can be used to develop a protocol for elective total knee arthroplasty (TKA) and total hip arthroplasty (THA). Study Design: This review focuses on potential components of the protocol relevant to surgeons; anesthesia components are reported separately. Components were identified through review of existing pathways and from consultation with technical experts. For each, a structured review of MEDLINE identified systematic reviews, randomized trials, and observational studies that reported on these components in patients undergoing elective TKA/THA. This primary evidence review was combined with existing clinical guidelines in a narrative format. Results: Sixteen components were reviewed. Of the 10 preoperative components, most were focused on risk factor assessment including anemia, diabetes mellitus, tobacco use, obesity, nutrition, immune-modulating therapy, and opiates. Preoperative education, venous thromboembolism (VTE) prophylaxis, and bathing/Staphylococcus aureus decolonization were also included. The routine use of drains was the only intraoperative component evaluated. The 5 postoperative components included early mobilization, continuous passive motion, extended duration VTE prophylaxis, early oral alimentation, and discharge planning. Conclusion: This review synthesizes the evidence supporting potential surgical components of an ERP for elective TKA/THA. The AHRQ Safety Program for Improving

  20. Surgical Technical Evidence Review for Elective Total Joint Replacement Conducted for the AHRQ Safety Program for Improving Surgical Care and Recovery.

    Science.gov (United States)

    Childers, Christopher P; Siletz, Anaar E; Singer, Emily S; Faltermeier, Claire; Hu, Q Lina; Ko, Clifford Y; Golladay, Gregory J; Kates, Stephen L; Wick, Elizabeth C; Maggard-Gibbons, Melinda

    2018-01-01

    Use of enhanced recovery pathways (ERPs) can improve patient outcomes, yet national implementation of these pathways remains low. The Agency for Healthcare Research and Quality (AHRQ; funder), the American College of Surgeons, and the Johns Hopkins Medicine Armstrong Institute for Patent Safety and Quality have developed the Safety Program for Improving Surgical Care and Recovery-a national effort to catalyze implementation of practices to improve perioperative care and enhance recovery of surgical patients. This review synthesizes evidence that can be used to develop a protocol for elective total knee arthroplasty (TKA) and total hip arthroplasty (THA). This review focuses on potential components of the protocol relevant to surgeons; anesthesia components are reported separately. Components were identified through review of existing pathways and from consultation with technical experts. For each, a structured review of MEDLINE identified systematic reviews, randomized trials, and observational studies that reported on these components in patients undergoing elective TKA/THA. This primary evidence review was combined with existing clinical guidelines in a narrative format. Sixteen components were reviewed. Of the 10 preoperative components, most were focused on risk factor assessment including anemia, diabetes mellitus, tobacco use, obesity, nutrition, immune-modulating therapy, and opiates. Preoperative education, venous thromboembolism (VTE) prophylaxis, and bathing/ Staphylococcus aureus decolonization were also included. The routine use of drains was the only intraoperative component evaluated. The 5 postoperative components included early mobilization, continuous passive motion, extended duration VTE prophylaxis, early oral alimentation, and discharge planning. This review synthesizes the evidence supporting potential surgical components of an ERP for elective TKA/THA. The AHRQ Safety Program for Improving Surgical Care and Recovery aims to guide hospitals and

  1. Austenitic stainless steel-to-ferritic steel transition joint welding for elevated temperature service

    International Nuclear Information System (INIS)

    King, J.F.; Goodwin, G.M.; Slaughter, G.M.

    1978-01-01

    Transition weld joints between ferritic steels and austenitic stainless steels are required for fossil-fired power plants and proposed nuclear plants. The experience with these dissimilar-metal transition joints has been generally satisfactory, but an increasing number of failures of these joints is occurring prematurely in service. These concerns with transition joint service history prompted a program to develop more reliable joints for application in proposed nuclear power plants

  2. JET Joint Undertaking

    International Nuclear Information System (INIS)

    Keen, B.E.

    1987-03-01

    The paper presents the progress report of the Joint European Torus (JET) Joint Undertaking, 1986. The report contains a survey of the scientific and technical achievements on JET during 1986; the more important articles referred to in this survey are reproduced as appendices to this Report. The last section discusses developments which might improve the overall performance of the machine. (U.K.)

  3. 13. Sacroiliac joint pain

    NARCIS (Netherlands)

    Vanelderen, P.; Szadek, K.M.; Cohen, S.P.; Witte, J.; Lataster, A.; Patijn, J.; Mekhail, N.; van Kleef, M.; van Zundert, J.

    2010-01-01

    The sacroiliac joint accounts for approximately 16% to 30% of cases of chronic mechanical low back pain. Pain originating in the sacroiliac joint is predominantly perceived in the gluteal region, although pain is often referred into the lower and upper lumbar region, groin, abdomen, and/ or lower

  4. Transversely Compressed Bonded Joints

    DEFF Research Database (Denmark)

    Hansen, Christian Skodborg; Schmidt, Jacob Wittrup; Stang, Henrik

    2012-01-01

    The load capacity of bonded joints can be increased if transverse pressure is applied at the interface. The transverse pressure is assumed to introduce a Coulomb-friction contribution to the cohesive law for the interface. Response and load capacity for a bonded single-lap joint was derived using...

  5. Joint Newspaper Operating Agreements.

    Science.gov (United States)

    Parsons, Marie

    The number of competing daily newspapers in American cities has dwindled until only about 50 cities boast two papers. Of the newspapers in those cities, 23 now maintain separate editorial operations but have joint printing, advertising, and circulation departments. The concept of joint operation is 50 years old, dating from the Depression years…

  6. Joint Hub Network Development

    NARCIS (Netherlands)

    Cruijssen, F.C.A.M.; Borm, P.E.M.; Dullaert, W.; Hamers, H.J.M.

    2007-01-01

    This paper introduces a framework for joint hub network development. Building a joint physical hub for transhipment of goods is expensive and therefore involves considerable risks for the cooperating companies. In a practical setting, it is unlikely that an entire network will be built at once.

  7. Elbow joint instability

    DEFF Research Database (Denmark)

    Olsen, Bo Sanderhoff; Henriksen, M G; Søjbjerg, Jens Ole

    1994-01-01

    The effect of simultaneous ulnar and radial collateral ligament division on the kinematics of the elbow joint is studied in a cadaveric model. Severance of the anterior part of the ulnar collateral ligament and the annular ligament led to significant elbow joint instability in valgus and varus...

  8. Bistable Articulated Joint

    Science.gov (United States)

    Graighead, Norwood D., II; Preliasco, R. J.; Hult, T. D.

    1986-01-01

    Joint with four-bar-linkage geometry has following attributes: Springs to fully extended fully folded positions. Automatically locks in its extended position. Joint combines zero backlash, positive locking, and centerline pivoting. Used in folding tool handles, portable antenna booms, and many other deployable structures.

  9. MP Joint Arthritis

    Science.gov (United States)

    ... All Topics A-Z Videos Infographics Symptom Picker Anatomy Bones Joints Muscles Nerves Vessels Tendons About Hand Surgery What is a Hand Surgeon? What is a Hand Therapist? Media Find a Hand Surgeon Home Anatomy MP Joint Arthritis Email to a friend * required ...

  10. Creep of timber joints

    NARCIS (Netherlands)

    Van de Kuilen, J.W.G.

    2008-01-01

    A creep analysis has been performed on nailed, toothed-plates and split-ring joints in a varying uncontrolled climate. The load levels varied between 30% and 50% of the average ultimate short term strength of these joints, tested in accordance with ISO 6891. The climate in which the tests were

  11. MR diagnosis of temporomandibular joint. A study of joint effusion

    International Nuclear Information System (INIS)

    Kaneda, Takashi; Yamashiro, Mitsuaki; Ozawa, Kaoru; Suzuki, Hiromi; Okada, Hiroyuki; Yamamoto, Hirotsugu

    1998-01-01

    The purposes of this study were to evaluate the relationship between correlation of MR joint effusion of the temporomandibular joint and disk position, to evaluate the relationship between joint effusion and aging, and to assess the frequency of MR joint effusion of bilateral temporomandibular joints. The temporomandibular joints of 192 patients with clinical symptoms of temporomandibular joint disorders were imaged bilaterally using high field, surface-coil MR imaging. Oblique sagittal and coronal proton density-weighted and T2-weighted images were obtained. Imaging findings of joint effusion were correlated with disk position, aging, and bilateral temporomandibular joints. MR showed effusion in 4% of the joints with normal superior disk position, 36% of the joints with disk displacement with reduction, and 45% of the joints with disk displacement without reduction. There were significant differences in the incidence of joint effusion between normal disk position and anterior disk displacement with or without reduction. Younger patients less than 40 years were significant higher the incidence of joint effusion than those of older patients. A significant association was seen between joint effusion and aging. MR showed effusion in 17% of the unilateral temporomandibular joint, 24% of the bilateral temporomandibular joints. There was no significant difference between unilateral and bilateral case. These results indicated that joint effusion using MR imaging was associated with varied temporomandibular joint pathologic states. (author)

  12. Generalised joint hypermobility and knee joint hypermobility

    DEFF Research Database (Denmark)

    Junge, Tina; Henriksen, Peter; Hansen, Sebrina

    2018-01-01

    . Respondents with GJHk and KJH reported lower HRQoL. CONCLUSION: GJHk and KJH were frequently reported in the Danish adult population, mostly in women. Respondents with GJHk and KJH were two times more likely to report knee joint-related symptoms such as pain, reduced performance of usual activity and lower...

  13. Space Suit Joint Torque Testing

    Science.gov (United States)

    Valish, Dana J.

    2011-01-01

    In 2009 and early 2010, a test was performed to quantify the torque required to manipulate joints in several existing operational and prototype space suits in an effort to develop joint torque requirements appropriate for a new Constellation Program space suit system. The same test method was levied on the Constellation space suit contractors to verify that their suit design meets the requirements. However, because the original test was set up and conducted by a single test operator there was some question as to whether this method was repeatable enough to be considered a standard verification method for Constellation or other future space suits. In order to validate the method itself, a representative subset of the previous test was repeated, using the same information that would be available to space suit contractors, but set up and conducted by someone not familiar with the previous test. The resultant data was compared using graphical and statistical analysis and a variance in torque values for some of the tested joints was apparent. Potential variables that could have affected the data were identified and re-testing was conducted in an attempt to eliminate these variables. The results of the retest will be used to determine if further testing and modification is necessary before the method can be validated.

  14. Evaluation of two transport aircraft and several ground test vehicle friction measurements obtained for various runway surface types and conditions. A summary of test results from joint FAA/NASA Runway Friction Program

    Science.gov (United States)

    Yager, Thomas J.; Vogler, William A.; Baldasare, Paul

    1990-01-01

    Tests with specially instrumented NASA Boeing 737 and 727 aircraft together with several different ground friction measuring devices were conducted for a variety of runway surface types and conditions. These tests are part of joint FAA/NASA Aircraft/Ground Vehicle Runway Friction Program aimed at obtaining a better understanding of aircraft ground handling performance under adverse weather conditions and defining relationships between aircraft and ground vehicle tire friction measurements. Aircraft braking performance on dry, wet, snow and ice-covered runway conditions is discussed as well as ground vehicle friction data obtained under similar runway conditions. For a given contaminated runway surface condition, the correlation between ground vehicles and aircraft friction data is identified. The influence of major test parameters on friction measurements such as speed, test tire characteristics, type and amount of surface contaminant, and ambient temperature are discussed. The effect of surface type on wet friction levels is also evaluated from comparative data collected on grooved and ungrooved concrete and asphalt surfaces.

  15. Fiscal 1999 research report. Basic research for promotion of joint implementation programs (Basic research on energy efficiency at Novolipetsk Iron and Steel Works); 1999 nendo Novolipetsk seitetsushosho energy kihon chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    A survey is conducted about whether energy efficiency improving facilities will be appropriately accommodated by the sintering process, blast furnace process, steelmaking process, and the energy process that consume energy in large quantities at the Novolipetsk Iron and Steel Works which represents Russia's steelmaking plants, which is for scouting out a project to develop into a joint implementation activity in the future. The result shows that the amount of natural gas for domestic power generators in the steelworks or the amount of power to be purchased will be reduced when large-scale exhaust heat recovery facilities are adopted. A study of the energy profile shows that there is no problem to impede the implementation of this program. Regarding the introduction of energy saving measures into the respective processes, the results of investigations conducted into the respective processes are subjected to a macroscopic study. The facilities involved include a sintering cooler exhaust heat recovery facility, hot blast furnace waste heat recovery facility, TRT (power generation by blast furnace top-pressure recovery turbines) facility, and an LDG (basic oxygen gas) recovery facility. Upon adoption of all these facilities, there will be a reduction in green effect gas (CO2) emissions of approximately 410,000 tons/year, for which a total of 20.9-billion yen will have to be invested. (NEDO)

  16. A Chronosequence Feasibility Assessment of Emergency Fire Rehabilitation Records within the Intermountain Western United States - Final Report to the Joint Fire Science Program - Project 08-S-08

    Science.gov (United States)

    Knutson, Kevin C.; Pyke, David A.; Wirth, Troy A.; Pilliod, David S.; Brooks, Matthew L.; Chambers, Jeanne C.

    2009-01-01

    Department of the Interior (DOI) bureaus have invested heavily (for example, the U.S. Bureau of Land Management (BLM) spent more than $60 million in fiscal year 2007) in seeding vegetation for emergency stabilization and burned area rehabilitation of non-forested arid lands over the past 10 years. The primary objectives of these seedings commonly are to (1) reduce the post-fire dominance of non-native annual grasses, such as cheatgrass (Bromus tectorum) and red brome (Bromus rubens); (2) minimize the probability of recurrent fire; and (3) ultimately produce desirable vegetation characteristics (for example, ability to recover following disturbance [resilience], resistance to invasive species, and a capacity to support a diverse flora and fauna). Although these projects historically have been monitored to varying extents, land managers currently lack scientific evidence to verify whether seeding arid and semiarid lands achieves desired objectives. Given the amount of resources dedicated to post-fire seeding projects, a synthesis of information determining the factors that result in successful treatments is critically needed. Although results of recently established experiments and monitoring projects eventually will provide useful insights for the future direction of emergency stabilization and burned area rehabilitation programs, a chronosequence approach evaluating emergency stabilization and burned area rehabilitation treatments (both referenced hereafter as ESR treatments) over the past 30 years could provide a comprehensive assessment of treatment success across a range of regional environmental gradients. By randomly selecting a statistically robust sample from the population of historic ESR treatments in the Intermountain West, this chronosequence approach would have inference for most ecological sites in this region. The goal of this feasibility study was to compile and examine historic ESR records from BLM field offices across the Intermountain West to

  17. Multielement trace determination in SiC powders: assessment of interlaboratory comparisons aimed at the validation and standardization of analytical procedures with direct solid sampling based on ETV ICP OES and DC arc OES.

    Science.gov (United States)

    Matschat, Ralf; Hassler, Jürgen; Traub, Heike; Dette, Angelika

    2005-12-01

    The members of the committee NMP 264 "Chemical analysis of non-oxidic raw and basic materials" of the German Standards Institute (DIN) have organized two interlaboratory comparisons for multielement determination of trace elements in silicon carbide (SiC) powders via direct solid sampling methods. One of the interlaboratory comparisons was based on the application of inductively coupled plasma optical emission spectrometry with electrothermal vaporization (ETV ICP OES), and the other on the application of optical emission spectrometry with direct current arc (DC arc OES). The interlaboratory comparisons were organized and performed in the framework of the development of two standards related to "the determination of mass fractions of metallic impurities in powders and grain sizes of ceramic raw and basic materials" by both methods. SiC powders were used as typical examples of this category of material. The aim of the interlaboratory comparisons was to determine the repeatability and reproducibility of both analytical methods to be standardized. This was an important contribution to the practical applicability of both draft standards. Eight laboratories participated in the interlaboratory comparison with ETV ICP OES and nine in the interlaboratory comparison with DC arc OES. Ten analytes were investigated by ETV ICP OES and eleven by DC arc OES. Six different SiC powders were used for the calibration. The mass fractions of their relevant trace elements were determined after wet chemical digestion. All participants followed the analytical requirements described in the draft standards. In the calculation process, three of the calibration materials were used successively as analytical samples. This was managed in the following manner: the material that had just been used as the analytical sample was excluded from the calibration, so the five other materials were used to establish the calibration plot. The results from the interlaboratory comparisons were summarized and

  18. Joint Electromagnetic Spectrum Management Operations

    Science.gov (United States)

    2012-03-20

    promulgate command-specific policy and guidance for EMS use, the joint restricted frequency list (JRFL) process, the joint communications–electronics...joint communications–electronics operating instructions (JCEOI) and joint restricted frequency list (JRFL). Examples of FM include providing the...joint restricted frequency list Figure III-4. Joint Frequency Management Office Spectrum Management Process Chapter III III-10 JP 6-01 assignments

  19. Critical joints in large composite aircraft structure

    Science.gov (United States)

    Nelson, W. D.; Bunin, B. L.; Hart-Smith, L. J.

    1983-01-01

    A program was conducted at Douglas Aircraft Company to develop the technology for critical structural joints of composite wing structure that meets design requirements for a 1990 commercial transport aircraft. The prime objective of the program was to demonstrate the ability to reliably predict the strength of large bolted composite joints. Ancillary testing of 180 specimens generated data on strength and load-deflection characteristics which provided input to the joint analysis. Load-sharing between fasteners in multirow bolted joints was computed by the nonlinear analysis program A4EJ. This program was used to predict strengths of 20 additional large subcomponents representing strips from a wing root chordwise splice. In most cases, the predictions were accurate to within a few percent of the test results. In some cases, the observed mode of failure was different than anticipated. The highlight of the subcomponent testing was the consistent ability to achieve gross-section failure strains close to 0.005. That represents a considerable improvement over the state of the art.

  20. 7 CFR 760.113 - Refunds; joint and several liability.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Refunds; joint and several liability. 760.113 Section... Agricultural Disaster Assistance Programs § 760.113 Refunds; joint and several liability. (a) In the event that... provided that interest will in all cases run from the date of the original disbursement. (b) All persons...

  1. ETV laiendab filmiskaalat / Tarmo Teder

    Index Scriptorium Estoniae

    Teder, Tarmo, 1958-

    2003-01-01

    Eesti Televisioonis näidatud filme - Concordia tudengite "Hüvasti igaveseks, Värdjad!" : autorid Liina Paakspuu, Kadriann Kibus ja dokumentaalfilm sõjafotograaf James Nachtwey'st "Sõjafotograaf" ("War Photographer") : autor Christian Frei : Šveits 2001

  2. Joint Quantum Institute

    Data.gov (United States)

    Federal Laboratory Consortium — The Joint Quantum Institute (JQI) is pursuing that goal through the work of leading quantum scientists from the Department of Physics of the University of Maryland...

  3. Temporomandibular Joint Disorder

    Science.gov (United States)

    ... Baby Bottle Tooth Decay? Pacifiers Have Negative and Positive Effects What is Dental Amalgam (Silver Filling)? Check Menstrual Calendar for Tooth Extraction Temporomandibular Joint Disorder Learn what those dental words mean. Check out how your teeth and mouth ...

  4. Hip joint replacement

    Science.gov (United States)

    Hip arthroplasty; Total hip replacement; Hip hemiarthroplasty; Arthritis - hip replacement; Osteoarthritis - hip replacement ... Your hip joint is made up of 2 major parts. One or both parts may be replaced during surgery: ...

  5. Knee joint replacement

    Science.gov (United States)

    ... to make everyday tasks easier. Practice using a cane, walker , crutches , or a wheelchair correctly. On the ... ask your doctor Knee joint replacement - discharge Preventing falls Preventing falls - what to ask your doctor Surgical ...

  6. Concrete pavement joint deterioration.

    Science.gov (United States)

    2015-12-01

    Concrete pavements are an important part of our national infrastructure. In recent years the relatively small number of reported joints deteriorating prematurely in concrete pavements around Indiana has increased. Changes over the past 45 years in IN...

  7. Sacroiliac joint dysfunction.

    Science.gov (United States)

    Ilaslan, Hakan; Arslan, Ahmet; Koç, Omer Nadir; Dalkiliç, Turker; Naderi, Sait

    2010-07-01

    Sacroiliac joint dysfunction is a disorder presenting with low back and groin pain. It should be taken into consideration during the preoperative differential diagnosis of lumbar disc herniation, lumbar spinal stenosis and facet syndrome. Four cases with sacroiliac dysfunction are presented. The clinical and radiological signs supported the evidence of sacroiliac dysfunction, and exact diagnosis was made after positive response to sacroiliac joint block. A percutaneous sacroiliac fixation provided pain relief in all cases. The mean VAS scores reduced from 8.2 to 2.2. It is concluded that sacroiliac joint dysfunction diagnosis requires a careful physical examination of the sacroiliac joints in all cases with low back and groin pain. The diagnosis is made based on positive response to the sacroiliac block. Sacroiliac fixation was found to be effective in carefully selected cases.

  8. Joint Hub Network Development

    OpenAIRE

    Cruijssen, F.C.A.M.; Borm, P.E.M.; Dullaert, W.; Hamers, H.J.M.

    2007-01-01

    This paper introduces a framework for joint hub network development. Building a joint physical hub for transhipment of goods is expensive and therefore involves considerable risks for the cooperating companies. In a practical setting, it is unlikely that an entire network will be built at once. Rather, the partners will have a more cautious attitude and build the hub facilities one-by-one. In the proposed framework, every time a new hub is introduced, partners will have the opportunity to dec...

  9. Prosthetic Joint Infections

    Science.gov (United States)

    Aslam, Saima; Darouiche, Rabih O.

    2012-01-01

    Prosthetic joint infections represent a major therapeutic challenge for both healthcare providers and patients. This paper reviews the predisposing factors, pathogenesis, microbiology, diagnosis, treatment and prophylaxis of prosthetic joint infection. The most optimal management strategy should be identified based on a number of considerations including type and duration of infection, antimicrobial susceptibility of the infecting pathogen, condition of infected tissues and bone stock, patient wishes and functional status. PMID:22847032

  10. Benign joint hypermobility syndrome

    Directory of Open Access Journals (Sweden)

    Iwona Słowińska

    2014-11-01

    Full Text Available Benign joint hypermobility syndrome (BJHS, commonly known as loose ligament syndrome, is a non-inflammatory rheumatic condition. It is characterised by a greater than normal range of motion of the joints of the limbs and spine. The prevalence of the syndrome in preschool-age children is estimated to be between 2% and 30%, depending on ethnic background (with higher prevalence in Asian and African populations, occurring most often in families with a history of the condition and more frequently in girls. This paper presents a case report of a 12-year-old girl. A broad differential diagnostic approach to recurrent joint inflammation with joint effusion and pain made it possible to establish a diagnosis of benign joint hypermobility syndrome. The child met the Brighton criteria; her Beighton score was 7 out of 9. Patient education aimed at eliminating abnormal joint movement and an appropriate rehabilitation programme play key roles in the treatment of BJHS.

  11. Improvement of Hungarian Joint Terminal Attack Program

    Science.gov (United States)

    2013-06-13

    LST Laser Spot Tracker NVG Night Vision Goggle ROMAD Radio Operator Maintainer and Driver ROVER Remotely Operated Video Enhanced Receiver TACP...visual target designation. The other component consists of a laser spot tracker (LST), which identifies targets by tracking laser energy reflecting...capability for every type of night time missions, laser spot tracker for laser spot search missions, remotely operated video enhanced receiver

  12. Joint General Atomic-TAERF fusion program

    Energy Technology Data Exchange (ETDEWEB)

    Kerst, D W [John Jay Hopkins Laboratory for Pure and Applied Science, General Atomic Division of General Dynamics Corporation, San Diego, CA (United States)

    1958-07-01

    The experimental work has consisted of several parts: the study of charge exchange in hydrogen ionic and atomic collisions, the study of some linear pinch discharge systems with high stabilizing axial magnetic fields, developments on a small scale for a large toroidal geometry, and experiments with various diagnostic methods, including electrical, optical, and shock-tube methods. The experiments on atomic collisions have consisted of measurements of cross sections for the ionization, the excitation of Lyman-alpha radiation, and elastic scattering for the case of electron bombardment. In addition, charge-exchange cross sections between deuterons and deuterium atoms have been measured. The calculations of Dalgarno and Yadav, using a perturbed stationary-state approximation are close to the experimental results which show a very large cross section for charge exchange.

  13. NASA/University Joint Venture (JOVE) Program

    Science.gov (United States)

    Magee-Sauer, Karen P.

    1999-01-01

    Hale-Bopp observations at the NASA IRTF concluded in September 1997. For the post Hale-Bopp period, telescope time was awarded to study comet Giacobini-Zinner in October 1998 at the NASA IRTF. A total of 6 nights were awarded to our team to study the comet where 2 of those 6 nights were awarded to Magee-Sauer as the principal investigator. Other observing trips were awarded to study YSOs (October 1998) and Mars (spring 1999) were Magee-Sauer was a co-investigator. An observing run from July 4 -7 1999 included study of Mars and YSOS. Our group has started to use the NIRSPEC instrument on the Keck II telescope. In collaboration with the development team from UCLA, we obtained images of comet Lee in August 1999. Telescope proposals are submitted each semester for targeted comet observations when a comet is bright enough to observe.

  14. Do Joint Fighter Programs Save Money?

    Science.gov (United States)

    2013-01-01

    Reports & Bookstore Make a charitable contribution Limited Electronic Distribution Rights This document and trademark(s) contained herein are protected by...reflect the opinions of its research clients and sponsors. Support RAND—make a tax-deductible charitable contribution at www.rand.org/giving...Ahn, Sanghoon, Competition, Innovation and Productivity Growth: A Review of Theory and Evidence, Paris: Organisation for Economic Co-Operation and

  15. Joint Services Electronics Program Progress Report.

    Science.gov (United States)

    1982-09-30

    and Detectors," David B. Rutledge. This thesis has the following abstract: Integrated-circuit techniques promise to make possible reliable...T. DeGraauw, H. Van De Stadt, D. Bicanic, and B. Zuidberg, Infrared Physics, 16, 233, 1976. (13) H. R. Fetterman , B. J. Clifton, P. E. Tannenwald...and C. D. Parker, Appl. Phys. Lett., 24, 70, 1974. (14) H. R. Fetterman , B. J. Clifton, P. E. Tannenwald, C. D. Parker, and H. Penfield, IEEE Trans

  16. Jointness for the Rest of Us: Reforming Joint Professional Development

    Science.gov (United States)

    2016-06-10

    transferred to the Joint Staff. 13 DOD’s instinct to “overly centralize planning, organization, and management.”20 The authors contend that this...2. 3 John F. Schank and others, Who is Joint? Reevaluating the Joint Duty Assignment List : A Study Prepared for the Joint Staff, by the RAND...and code those billets as such. Once identified, DOD must expand the Joint Duty Assignment List (JDAL) to include billets that offer enlisted personnel

  17. Joint studies on large CANDU

    International Nuclear Information System (INIS)

    Lee, Ikhwan; Yu, S. K. W.

    1994-01-01

    from economic, safety and strategic viewpoints. A large number of research and development programs are now in place at AECL and KAERI that will permit substantial improvements to be realized in the next generation of CANDU okabts, Furthermore, opportunities exist for engineered improvements based on the research and development in advancing the generic CANDU Technology. Final Large CANDU joint study report with technical deliverables will be issued 1994 October. Phase 2 R and D program of the joint studies will be determined this year and implemented in next year. CANDU neutron economy permits versatility in choices of fuel cycles. This allows a utility to choose fuel cycle options for lower fuelling cost, better security of supply, and ultimately for much lower spent-fuel volume, than with PWR's alone. To meet Korea's strategic requirements, CANDU should be an integral part of the electricity supply mix.

  18. Distributionally Robust Joint Chance Constrained Problem under Moment Uncertainty

    Directory of Open Access Journals (Sweden)

    Ke-wei Ding

    2014-01-01

    Full Text Available We discuss and develop the convex approximation for robust joint chance constraints under uncertainty of first- and second-order moments. Robust chance constraints are approximated by Worst-Case CVaR constraints which can be reformulated by a semidefinite programming. Then the chance constrained problem can be presented as semidefinite programming. We also find that the approximation for robust joint chance constraints has an equivalent individual quadratic approximation form.

  19. Flat H Frangible Joint Evolution

    Science.gov (United States)

    Diegelman, Thomas E.; Hinkel, Todd J.; Benjamin, Andrew; Rochon, Brian V.; Brown, Christopher W.

    2016-01-01

    Space vehicle staging and separation events require pyrotechnic devices. They are single-use mechanisms that cannot be tested, nor can failure-tolerant performance be demonstrated in actual flight articles prior to flight use. This necessitates the implementation of a robust design and test approach coupled with a fully redundant, failure-tolerant explosive mechanism to ensure that the system functions even in the event of a single failure. Historically, NASA has followed the single failure-tolerant (SFT) design philosophy for all human-rated spacecraft, including the Space Shuttle Program. Following the end of this program, aerospace companies proposed building the next generation human-rated vehicles with off-the-shelf, non-redundant, zero-failure-tolerant (ZFT) separation systems. Currently, spacecraft and launch vehicle providers for both the Orion and Commercial Crew Programs (CCPs) plan to deviate from the heritage safety approach and NASA's SFT human rating requirements. Both programs' partners have base-lined ZFT frangible joints for vehicle staging and fairing separation. These joints are commercially available from pyrotechnic vendors. Non-human-rated missions have flown them numerous times. The joints are relatively easy to integrate structurally within the spacecraft. In addition, the separation event is debris free, and the resultant pyro shock is lower than that of other design solutions. It is, however, a serious deficiency to lack failure tolerance. When used for critical applications on human-rated vehicles, a single failure could potentially lead to loss of crew (LOC) or loss of mission (LOM)). The Engineering and Safety & Mission Assurance directorates within the NASA Johnson Space Center took action to address this safety issue by initiating a project to develop a fully redundant, SFT frangible joint design, known as the Flat H. Critical to the ability to retrofit on launch vehicles being developed, the SFT mechanisms must fit within the same

  20. Acromioclavicular joint separation

    Directory of Open Access Journals (Sweden)

    Devan Pandya, BS

    2018-04-01

    Full Text Available History of present illness: A 30-year-old male was brought in by ambulance to the emergency department as a trauma activation after a motorcycle accident. The patient was the helmeted rider of a motorcycle traveling at an unknown speed when he lost control and was thrown off his vehicle. He denied loss of consciousness, nausea, or vomiting. The patient’s vital signs were stable and his only complaint was pain around his left shoulder. On exam, the patient had a prominent left clavicle without skin compromise. He had adequate range of motion in the left shoulder with moderate pain, and his left upper extremity was neurovascularly intact. Significant findings: Plain films of the left shoulder showed elevation of the left clavicle above the acromion. There was an increase in the acromioclavicular (AC and coracoclavicular (CC distances (increased joint distances marked with red and blue arrows, respectively. A normal AC joint measures 1-3 mm whereas a normal CC distance measures 11-13 mm.1 The injury was classified as a Rockwood type III AC joint separation. Discussion: The AC joint is a synovial joint between an oval facet on the acromion and a similar facet on the distal end of the clavicle. Horizontal stability is provided by the AC joint while axial stability is provided by the CC joint.2,3 AC joint injuries account for about 9%-12% of shoulder girdle injuries, and the most common mechanism is direct trauma.4,5 Initial evaluation with imaging includes plain films with three views: the anterior-posterior (AP view with the shoulder in internal and external rotation as well as an axillary, or scapula-Y view (sensitivity 40%, specificity 90% for all films.6,7 AC joint injuries are classified by the Rockwood system.8 Type I involves a sprain or incomplete tear of the AC ligaments with an intact CC ligament. The AC joint appears normal on X-ray, but can become widened with stress, achieved by having the patient hold a 10-15 pound weight from each

  1. Forming a multinational joint venture

    International Nuclear Information System (INIS)

    Bhatia, N.K.; Garb, R.H.; Statton, T.D.

    1990-01-01

    This paper discusses the basis and mechanics for forming a multinational joint venture. The topics of the paper include the motivations for a joint venture, selection of the appropriate co-venturer, management of the multinational joint venture, and the joint venture agreement. The authors state that a joint venture is not applicable or desirable in all instances and to be successful, must be carefully planned

  2. Facet joint syndrome

    International Nuclear Information System (INIS)

    Zigrai, M.; Zakovic, J.; Brezinova, M.; Pavlovicova, M.

    2002-01-01

    It is the purpose of the study to demonstrate the clinical relevance of degenerative changes in the facet joint of patients with low back pain irradiating to the lower extremities, and discuss some problems relating to diagnosis and different diagnosis. 119 patients presenting the listed bellow syndromes are covered by the study: scoliosis, polytopic pain vertebral syndrome, paresis and history of trauma. all patients undergo comprehensive neurological examination with special attention focused on the spine: CT and plain x-rays are taken of the lumbosacral segment to assess the condition of the facet joints. The neurological examination demonstrates in all cases pain syndrome in the lumbar spine referred to one or both lower extremities. In 56% it is a matter of persisting pain, and in 44% - recurrent. More than half of the patients complain of sacroiliac (SI) dislocation and palpatory pain. Unilateral or bilateral degenerative changes are documented by imaging studies in all patients, including: subchondral thickening, osteopathy narrowing the lateral or central part of the spinal canal with ensuing nerve root compression. The lumbosacral zygoapophyseal joints are source of pseudoradicular pain. A correlation between clinical picture and GT changes is noted in all patients with facet joint syndrome. CT is an indispensable method in diagnosing facet joint syndrome. (authors)

  3. Temporomandibular joint examination reviewed

    Directory of Open Access Journals (Sweden)

    L. Guarda Nardini

    2011-09-01

    Full Text Available The temporo-mandibular joint (TMJ it’s a joint closely related to the skull base, the spine, and the jaws; all these anatomical structures must be taken in consideration when evaluating pain involving the tmj. In order to detect patients affected by pathology or dysfunctions of the tmj, physical examination is of great value in orienting the diagnosis. Inspection must consider the symmetry of the body, the dental status and the type of occlusion. Palpation is a way to assess contractiont involving the muscles of the masticatory system and of the neck. Auscultation, based on articular noise provides means to determine whether we are dealing with degeneration of the joint or a dislocation of the intrarticular disc. In order to confirm the diagnosis obtained with the clinical evaluation, it’s useful to perform imaging techniques as opt, tomography and TC of the tmj and electromyokineosiography – index of the mandibular functionality and of the muscles status. MRI and dynamic MRI are among the non invasive exams which give the greatest amount of information, regarding the disc position and the joint degeneration. Arthroscopy is an invasive technique that allows early diagnosis of degeneration and is helpful to reveal early inflammatory processes of the joint.

  4. Distal radioulnar joint injuries

    Directory of Open Access Journals (Sweden)

    Binu P Thomas

    2012-01-01

    Full Text Available Distal radioulnar joint is a trochoid joint relatively new in evolution. Along with proximal radioulnar joint , forearm bones and interosseous membrane, it allows pronosupination and load transmission across the wrist. Injuries around distal radioulnar joint are not uncommon, and are usually associated with distal radius fractures,fractures of the ulnar styloid and with the eponymous Galeazzi or Essex_Lopresti fractures. The injury can be purely involving the soft tissue especially the triangular fibrocartilage or the radioulnar ligaments.The patients usually present with ulnar sided wrist pain, features of instability, or restriction of rotation. Difficulty in carrying loads in the hand is a major constraint for these patients. Thorough clinical examination to localize point of tenderness and appropriate provocative tests help in diagnosis. Radiology and MRI are extremely useful, while arthroscopy is the gold standard for evaluation. The treatment protocols are continuously evolving and range from conservative, arthroscopic to open surgical methods. Isolated dislocation are uncommon. Basal fractures of the ulnar styloid tend to make the joint unstable and may require operative intervention. Chronic instability requires reconstruction of the stabilizing ligaments to avoid onset of arthritis. Prosthetic replacement in arthritis is gaining acceptance in the management of arthritis.

  5. Formation of Exfoliation Joints

    Science.gov (United States)

    Martel, S. J.

    2004-12-01

    The Earth's internal stresses interact with the topographic surface to affect many phenomena. Exfoliation joints, or sheeting joints, are widespread manifestations of this interaction. These opening-mode fractures form subparallel to the Earth's surface, bounding roughly concentric slabs of rock that resemble the layers of an onion. They occur worldwide in all major bedrock types, attain in-plane dimensions of hundreds of meters, exert a strong influence on groundwater flow, and help produce spectacular scenery, as in Yosemite National Park. The mechanism that causes them has been enigmatic. They are widely regarded as forming in response to "removal of overburden", but large fractures do not open in rocks merely by relieving a compressive stress. High fluid pressures, thermal effects, rock heterogeneity, and weathering also are rejected as primary causes of these fractures. Tensile stresses normal to the surface are required for large exfoliation fractures to open. Intriguingly, high surface-parallel compressive stresses are widely documented where exfoliation joints occur. Both numerical and analytical solutions for two-dimensional elastic bodies show that localized tensile stresses perpendicular to the ground surface must develop beneath certain topographies subject to strong compressive stresses parallel to the surface. This highly non-intuitive effect reflects the profound influence that topography can have on stresses near the surface of the Earth, and it can explain how exfoliation joints open. The theoretical results also indicate that exfoliation joint distributions could be used to infer the horizontal stresses near the Earth's surface.

  6. The temporomandibular joint

    International Nuclear Information System (INIS)

    Campbell, W.

    1984-01-01

    Whilst the temporomandibular joint is in many ways unique, it is subject to all the diseases and disorders found in joints in other parts of the human skeleton. By far the most common disorder is injury, followed by arthropathy, acute and chronic dislocations, ankylosis, and in rare instances, neoplasms. The diagnosis and management of the temporomandibular joint are the primary responsibility of the oral surgeon. Nevertheless, this anatomical region is an area in which the cooperation of medical and dental disciplines may be required for the satisfactory conclusion of treatment. The more so when the disease process involves either associated psychosomatic illness or malignancy. The mainstay of the diagnosis is a careful radiological examination of the joint. There exists a delicate relationship between the dentition, the muscles of mastication, and the temporomandibular articulation, which is controlled by arthrokinetic reflex activity of the branches of the 5th cranial nerve. Imbalance between one or more of the components of this integrated system frequently leads to disturbances in function. Pain-dysfunction disorders constitute the larger part of temporomandibular joint disturbances generally encountered

  7. Fractal Analysis of Rock Joint Profiles

    Science.gov (United States)

    Audy, Ondřej; Ficker, Tomáš

    2017-10-01

    Surface reliefs of rock joints are analyzed in geotechnics when shear strength of rocky slopes is estimated. The rock joint profiles actually are self-affine fractal curves and computations of their fractal dimensions require special methods. Many papers devoted to the fractal properties of these profiles were published in the past but only a few of those papers employed a convenient computational method that would have guaranteed a sound value of that dimension. As a consequence, anomalously low dimensions were presented. This contribution deals with two computational modifications that lead to sound fractal dimensions of the self-affine rock joint profiles. These are the modified box-counting method and the modified yard-stick method sometimes called the compass method. Both these methods are frequently applied to self-similar fractal curves but the self-affine profile curves due to their self-affine nature require modified computational procedures implemented in computer programs.

  8. 75 FR 33613 - Notice of the Carbon Sequestration-Geothermal Energy-Science Joint Workshop

    Science.gov (United States)

    2010-06-14

    ... Energy, DOE. ACTION: Notice of the Carbon Sequestration--Geothermal Energy--Science Joint Workshop... Fossil Energy-Carbon Sequestration Program will be holding a joint workshop on Common Research Themes for...-- http://www.geothermal.energy.gov . DATES: The Carbon Sequestration--Geothermal Energy--Science Joint...

  9. Total ankle joint replacement.

    Science.gov (United States)

    2016-02-01

    Ankle arthritis results in a stiff and painful ankle and can be a major cause of disability. For people with end-stage ankle arthritis, arthrodesis (ankle fusion) is effective at reducing pain in the shorter term, but results in a fixed joint, and over time the loss of mobility places stress on other joints in the foot that may lead to arthritis, pain and dysfunction. Another option is to perform a total ankle joint replacement, with the aim of giving the patient a mobile and pain-free ankle. In this article we review the efficacy of this procedure, including how it compares to ankle arthrodesis, and consider the indications and complications. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  10. MAJOR OUTCOMES OF THE WORK PERFORMED BY ST. PETERSBURG RESEARCH INSTITUTE OF RADIATION HYGIENE AFTER PROFESSOR P. V. RAMZAEV ON THE IMPLEMENTATION OF THE FEDERAL TARGETED PROGRAM “MITIGATION OF THE RADIATION ACCIDENTS’CONSEQUENCES UNTIL 2015” AND OF THE “JOINT ACTIVITIES PROGRAM ON MITIGATION OF THE CHERNOBYL DISASTER WITHIN THE UNION STATE FOR THE PERIOD UNTIL 2016“

    Directory of Open Access Journals (Sweden)

    A. N. Barkovskiy

    2016-01-01

    Full Text Available The article presents major results of the work performed by St. Petersburg Research Institute of Radiation Hygiene after Professor P. V. Ramzaev on public contracts signed within the implementation of the Federal targeted program “ Mitigation of the radiation accidents’ consequences for the period until 2015” ( Direction IV “ Streamlining of monitoring systems and their elements and situation forecasting on radioactively contaminated territories paragraph 14 “The analyses and comprehensive evaluation of radiation situation changes on radioactively contaminated territories “ aimed at compilation of radioactively contaminated zones’ settlements list and Direction VI “Awareness raising and social -psychological rehabilitation of radiation- affected residents”, paragraph 20 “Creation of unified informational system on ensuring population’s radiation safety and overcoming radiation accidents’ consequences via development of the federal and regional informational resources’ systems” and “ Joint activities program on mitigation of the Chernobyl disaster within the Union State for the period until 2016” ( Direction II “ Streamlining of unified radiation protection system in radioactively contaminated territories” paragraph 2.1 “ The harmonization of requirements, methods and technologies aimed at mitigation of Russian and Belorussian population’s internal and external exposure, the development of radiation control and monitoring unified system”, sub-paragraph 2.1.1 “The development of unified assessment and forecast system for population exposure doses and rationing of radionuclide – containing foodstuffs, agricultural products and forest preserves based on the international approaches” over the period from 2011 to 2015.

  11. JOINT INVOLVEMENT IN SYPHILIS

    Directory of Open Access Journals (Sweden)

    T. I. Zlobina

    2016-01-01

    Full Text Available Joint involvement in syphilis has been considered as casuistry in recent years. At the same time, the high incidence of primary syphilis and the notified cases of late neurosyphilis may suggest that joint involvement in this disease is by no means always verified. Traditionally there are two forms of syphilitic arthritis: primary synovial (involving the articular membranes and sac and primary bone (involving the articular bones and cartilages ones. The paper describes the authors' clinical case of the primary bone form of articular syphilis in a 34-year-old man. 

  12. Sacroiliac Joint Interventions.

    Science.gov (United States)

    Soto Quijano, David A; Otero Loperena, Eduardo

    2018-02-01

    Sacroiliac joint (SIJ) pain is an important cause of lower back problems. Multiple SIJ injection techniques have been proposed over the years to help in the diagnosis and treatment of this condition. However, the SIJ innervation is complex and variable, and truly intra-articular injections are sometimes difficult to obtain. Different sacroiliac joint injections have shown to provide pain relief in patients suffering this ailment. Various techniques for intraarticular injections, sacral branch blocks and radiofrequency ablation, both fluoroscopy guided and ultrasound guided are discussed in this paper. Less common techniques like prolotherapy, platelet rich plasma injections and botulism toxin injections are also discussed. Copyright © 2017 Elsevier Inc. All rights reserved.

  13. Prosthetic Joint Infection

    Science.gov (United States)

    Tande, Aaron J.

    2014-01-01

    SUMMARY Prosthetic joint infection (PJI) is a tremendous burden for individual patients as well as the global health care industry. While a small minority of joint arthroplasties will become infected, appropriate recognition and management are critical to preserve or restore adequate function and prevent excess morbidity. In this review, we describe the reported risk factors for and clinical manifestations of PJI. We discuss the pathogenesis of PJI and the numerous microorganisms that can cause this devastating infection. The recently proposed consensus definitions of PJI and approaches to accurate diagnosis are reviewed in detail. An overview of the treatment and prevention of this challenging condition is provided. PMID:24696437

  14. Imaging findings of charcot joint

    International Nuclear Information System (INIS)

    Meng Quanfei; Zhou Chunxiang; Chen Yingming; Jiang Bo

    2003-01-01

    Objective: To analyze the MRI characters of Charcot joint, and to evaluate the diagnostic value of X-ray, CT, and MRI on Charcot joint. Methods: Eight patients with 8 Charcot joints underwent X-ray, CT, and MR examinations. 6 of them had syringomyelia, 1 patient had injury of the spinal cord, and 1 case had diabetes. All 8 patients had sensory reduction or deficit in the sick extremities. Results: There were two types of Charcot joint, hypertrophic and atrophic. Radiographic and CT features of hypertrophic joint (n=3) showed hyperostotic osteosclerosis and mammoth osteophytes in the sick bones, periarticular ossification, and articular disorganization. Radiographic and CT features of atrophic joint (n=5) showed extensive bone resorption (destruction), periarticular debris, and articular disorganization. Main MRI features of Charcot joint included hydrarthrosis within joint capsule, thickened, loose, and elongated joint capsule with para-joint, peri-diaphysis, and inter-muscular extension in a pseudopodia pattern. The irregular joint capsule wall was presented as mild hypointensity on T 1 WI, slight hyper-intensity on T 2 WI, and was markedly enhanced after Gd-DTPA was administrated, which was considered as a characteristic manifestation of the lesion. Soft tissue mass containing hypo-intense stripes on both T 1 WI and T 2 WI was commonly noted adjacent to the involved joint. Conclusion: X-rays plain film is the first choice for the diagnosis of Charcot joint, and MRI is pretty useful in the diagnosis of Charcot joint

  15. Computational Intelligence : International Joint Conference

    CERN Document Server

    Rosa, Agostinho; Cadenas, José; Dourado, António; Madani, Kurosh; Filipe, Joaquim

    2016-01-01

    The present book includes a set of selected extended papers from the sixth International Joint Conference on Computational Intelligence (IJCCI 2014), held in Rome, Italy, from 22 to 24 October 2014. The conference was composed by three co-located conferences:  The International Conference on Evolutionary Computation Theory and Applications (ECTA), the International Conference on Fuzzy Computation Theory and Applications (FCTA), and the International Conference on Neural Computation Theory and Applications (NCTA). Recent progresses in scientific developments and applications in these three areas are reported in this book. IJCCI received 210 submissions, from 51 countries, in all continents. After a double blind paper review performed by the Program Committee, 15% were accepted as full papers and thus selected for oral presentation. Additional papers were accepted as short papers and posters. A further selection was made after the Conference, based also on the assessment of presentation quality and audience in...

  16. Computational Intelligence : International Joint Conference

    CERN Document Server

    Dourado, António; Rosa, Agostinho; Filipe, Joaquim; Kacprzyk, Janusz

    2016-01-01

    The present book includes a set of selected extended papers from the fifth International Joint Conference on Computational Intelligence (IJCCI 2013), held in Vilamoura, Algarve, Portugal, from 20 to 22 September 2013. The conference was composed by three co-located conferences:  The International Conference on Evolutionary Computation Theory and Applications (ECTA), the International Conference on Fuzzy Computation Theory and Applications (FCTA), and the International Conference on Neural Computation Theory and Applications (NCTA). Recent progresses in scientific developments and applications in these three areas are reported in this book. IJCCI received 111 submissions, from 30 countries, in all continents. After a double blind paper review performed by the Program Committee, only 24 submissions were accepted as full papers and thus selected for oral presentation, leading to a full paper acceptance ratio of 22%. Additional papers were accepted as short papers and posters. A further selection was made after ...

  17. Space Suit Joint Torque Measurement Method Validation

    Science.gov (United States)

    Valish, Dana; Eversley, Karina

    2012-01-01

    In 2009 and early 2010, a test method was developed and performed to quantify the torque required to manipulate joints in several existing operational and prototype space suits. This was done in an effort to develop joint torque requirements appropriate for a new Constellation Program space suit system. The same test method was levied on the Constellation space suit contractors to verify that their suit design met the requirements. However, because the original test was set up and conducted by a single test operator there was some question as to whether this method was repeatable enough to be considered a standard verification method for Constellation or other future development programs. In order to validate the method itself, a representative subset of the previous test was repeated, using the same information that would be available to space suit contractors, but set up and conducted by someone not familiar with the previous test. The resultant data was compared using graphical and statistical analysis; the results indicated a significant variance in values reported for a subset of the re-tested joints. Potential variables that could have affected the data were identified and a third round of testing was conducted in an attempt to eliminate and/or quantify the effects of these variables. The results of the third test effort will be used to determine whether or not the proposed joint torque methodology can be applied to future space suit development contracts.

  18. Temporomandibular Joint Septic Arthritis

    Directory of Open Access Journals (Sweden)

    Gianfranco Frojo, MD

    2018-01-01

    Full Text Available Summary:. Infection of the temporomandibular joint (TMJ is a rare pediatric condition resulting from the introduction of pathogens into the joint by hematogenous seeding, local extension, or trauma. Early recognition of the typical signs and symptoms including fever, trismus, preauricular swelling, and TMJ region tenderness are critical in order to initiate further evaluation and prevent feared complications of fibrosis, ankylosis, abnormal facial structure, or persistence of symptoms. Contrast-enhanced computed tomography with ancillary laboratory analysis including erythrocyte sedimentation rate, C-reactive protein, and white blood cell count are beneficial in confirming the suspected diagnosis and monitoring response to therapy. Initial intervention should include empiric parenteral antibiotics, early mandibular mobilization, and joint decompression to provide synovial fluid for analysis including cultures. This report describes a case of TMJ bacterial arthritis in a healthy 6-year-old male who was promptly treated nonsurgically with intravenous antibiotics and localized needle joint decompression with return to normal function after completion of oral antibiotics and physical therapy.

  19. Joint-Use Libraries

    Science.gov (United States)

    Casstevens, Susan

    2017-01-01

    The joint-use library is a place where people of all ages, interests, and income levels can find items of interest at no personal cost. The mission of A. H. Meadows Public and High School Library in Midlothian, Texas, is to offer what other public libraries provide: educational and entertainment resources to a community. Yet, the staff also wants…

  20. Keyed shear joints

    DEFF Research Database (Denmark)

    Hansen, Klaus

    This report gives a summary of the present information on the behaviour of vertical keyed shear joints in large panel structures. An attemp is made to outline the implications which this information might have on the analysis and design of a complete wall. The publications also gives a short...

  1. Jointness: A Selected Bibliography

    Science.gov (United States)

    2007-08-01

    AD-A431-767) http://handle.dtic.mil/100.2/ADA431767 Lamb , William L. Moving beyond Goldwater-Nichols: The Case for Continued Reform of the DoD...in Support of the Joint Force’." Army Aviation 55 (May 2006): 22-24. Magnuson, Stew . "Turf Battles: Strategic Command’s Expanded Portfolio

  2. Gonococcal Prosthetic Joint Infection.

    Science.gov (United States)

    Gassiep, Ian; Gilpin, Bradley; Douglas, Joel; Siebert, David

    2017-01-01

    Neisseria gonorrhoea is a common sexually transmitted infection worldwide. Disseminated gonococcal infection is an infrequent presentation and rarely can be associated with septic arthritis. Incidence of this infection is rising, both internationally and in older age groups. We present the first documented case of N. gonorrhoea prosthetic joint infection which was successfully treated with laparoscopic debridement and antimicrobial therapy.

  3. An analysis of a joint shear model for jointed media with orthogonal joint sets

    International Nuclear Information System (INIS)

    Koteras, J.R.

    1991-10-01

    This report describes a joint shear model used in conjunction with a computational model for jointed media with orthogonal joint sets. The joint shear model allows nonlinear behavior for both joint sets. Because nonlinear behavior is allowed for both joint sets, a great many cases must be considered to fully describe the joint shear behavior of the jointed medium. An extensive set of equations is required to describe the joint shear stress and slip displacements that can occur for all the various cases. This report examines possible methods for simplifying this set of equations so that the model can be implemented efficiently form a computational standpoint. The shear model must be examined carefully to obtain a computationally efficient implementation that does not lead to numerical problems. The application to fractures in rock is discussed. 5 refs., 4 figs

  4. Temporomandibular joint space in children without joint disease

    International Nuclear Information System (INIS)

    Larheim, T.A.

    1981-01-01

    Bilateral assessment of the temporomandibular joint space in children without joint disease is reported. Twenty-eight children were examined with conventional radiography and 23 with tomography. High prevalence of asymmetric joint spaces with both techniques indicated that great care should be taken when using narrowing or widening of the joint space as a diagnostic criterion in children with juvenile rheumatoid arthritis. Other signs, such as restricted translation of the mandibular head, and clinical symptoms should be evaluated. (Auth.)

  5. Anaerobic prosthetic joint infection.

    Science.gov (United States)

    Shah, Neel B; Tande, Aaron J; Patel, Robin; Berbari, Elie F

    2015-12-01

    In an effort to improve mobility and alleviate pain from degenerative and connective tissue joint disease, an increasing number of individuals are undergoing prosthetic joint replacement in the United States. Joint replacement is a highly effective intervention, resulting in improved quality of life and increased independence [1]. By 2030, it is predicted that approximately 4 million total hip and knee arthroplasties will be performed yearly in the United States [2]. One of the major complications associated with this procedure is prosthetic joint infection (PJI), occurring at a rate of 1-2% [3-7]. In 2011, the Musculoskeletal Infectious Society created a unifying definition for prosthetic joint infection [8]. The following year, the Infectious Disease Society of America published practice guidelines that focused on the diagnosis and management of PJI. These guidelines focused on the management of commonly encountered organisms associated with PJI, including staphylococci, streptococci and select aerobic Gram-negative bacteria. However, with the exception of Propionibacterium acnes, management of other anaerobic organisms was not addressed in these guidelines [1]. Although making up approximately 3-6% of PJI [9,10], anaerobic microorganisms cause devastating complications, and similar to the more common organisms associated with PJI, these bacteria also result in significant morbidity, poor outcomes and increased health-care costs. Data on diagnosis and management of anaerobic PJI is mostly derived from case reports, along with a few cohort studies [3]. There is a paucity of published data outlining factors associated with risks, diagnosis and management of anaerobic PJI. We therefore reviewed available literature on anaerobic PJI by systematically searching the PubMed database, and collected data from secondary searches to determine information on pathogenesis, demographic data, clinical features, diagnosis and management. We focused our search on five commonly

  6. Proceedings of the symposium on the joint research program between JAERI and Universities. Current status and future perspectives of the chemistry research in the nuclear fuel cycle back end field

    International Nuclear Information System (INIS)

    1999-10-01

    The first Symposium on the Joint Research Project between JAERI and Universities was held in Tokyo, January 27, 1999, to present the main achievements of the project in these 5 years and to discuss future perspectives of the chemistry research relating to the nuclear fuel cycle. The areas covered by the Joint Research Project are (1) Nuclear Chemistry for TRU Recycling, (2) Solid State Chemistry on Nuclear Fuels and Wastes, (3) Solution Chemistry on Fuel Reprocessing and Waste Management, and (4) Fundamental Chemistry on Radioactive Waste Disposal. The 8 papers are indexed individually. (J.P.N.)

  7. Longitudinal joint specifications and performance.

    Science.gov (United States)

    2012-08-01

    Deterioration of longitudinal joints is widely recognized as one of the major factors contributing to failure of asphalt pavements. Finding : ways to improve the durability of longitudinal joints will lead to improved service lives and lower life cyc...

  8. Swivel Joint For Liquid Nitrogen

    Science.gov (United States)

    Milner, James F.

    1988-01-01

    Swivel joint allows liquid-nitrogen pipe to rotate through angle of 100 degree with respect to mating pipe. Functions without cracking hard foam insulation on lines. Pipe joint rotates on disks so mechanical stress not transmitted to thick insulation on pipes. Inner disks ride on fixed outer disks. Disks help to seal pressurized liquid nitrogen flowing through joint.

  9. Joint audits - benefit or burden?

    DEFF Research Database (Denmark)

    Holm, Claus; Thinggaard, Frank

    a joint audit regime to a single auditor/voluntary joint audit regime. The dataset used in this paper has been collected for the full population of non-financial Danish companies listed on the Copenhagen Stock Exchange (CSE) in the years 2004 and 2005. We find that a majority of firms perceive joint...

  10. Joint International Accelerator School

    CERN Multimedia

    CERN Accelerator School

    2014-01-01

    The CERN and US Particle Accelerator Schools recently organised a Joint International Accelerator School on Beam Loss and Accelerator Protection, held at the Hyatt Regency Hotel, Newport Beach, California, USA from 5-14 November 2014. This Joint School was the 13th in a series of such schools, which started in 1985 and also involves the accelerator communities in Japan and Russia.   Photo courtesy of Alfonse Pham, Michigan State University.   The school attracted 58 participants representing 22 different nationalities, with around half from Europe and the other half from Asia and the Americas. The programme comprised 26 lectures, each of 90 minutes, and 13 hours of case study. The students were given homework each day and had an opportunity to sit a final exam, which counted towards university credit. Feedback from the participants was extremely positive, praising the expertise and enthusiasm of the lecturers, as well as the high standard and quality of their lectures. Initial dis...

  11. Posterolateral elbow joint instability

    DEFF Research Database (Denmark)

    Olsen, Bo Sanderhoff; Søjbjerg, Jens Ole; Nielsen, K K

    1998-01-01

    Thirty-five osteoligamentous elbows were included in a study on the kinematics of posterolateral elbow joint instability during the pivot shift test (PST) before and after separate ligament cuttings in the lateral collateral ligament complex (LCLC). Division of the annular ligament or the lateral...... ulnar collateral ligament caused no laxity during the PST. Division of the lateral collateral ligament caused maximal laxity of 4 degrees and 23 degrees during forced PST in valgus and external rotation (supination), respectively. Cutting of the LCLC at the ulnar or the humeral insertion was necessary...... for any PST stressed elbow joint laxity to occur. Total division of the LCLC induced a maximal laxity of 7.9 degrees and 37 degrees during forced PST in valgus and external rotation (supination), respectively. This study suggests the lateral collateral ligament to be the primary soft tissue constraint...

  12. JET Joint Undertaking

    International Nuclear Information System (INIS)

    Keen, B.E.; Lallia, P.; O'Hara, G.W.; Pollard, I.E.

    1987-06-01

    The paper presents the annual report of the Joint European Torus (JET) Joint Undertaking, 1986. The report is divided into two parts: a part on the scientific and technical programme of the project, and a part setting out the administration and organisation of the Project. The first part includes: a summary of the main features of the JET apparatus, the JET experimental programme, the position of the Project in the overall Euratom programme, and how JET relates to other large fusion devices throughout the world. In addition, the technical status of JET is described, as well as the results of the JET operations in 1986. The final section of the first part outlines the proposed future programme of JET. (U.K.)

  13. Peripheral degenerative joint diseases

    Directory of Open Access Journals (Sweden)

    Nilzio Antonio da Silva

    2008-03-01

    Full Text Available Osteoarthritis, a degenerative joint disease, is the most commonrheumatic disorder mainly in a geriatric population. Manifestationsare pain, stiffness and functional loss in the affected joint.According to etiology it is classifi ed as primary (or idiopathicand secondary. Some risk factors for disease development aregenetics, race, age, sex, obesity, occupational activities andarticular biomechanics. Pathogenesis is the same for any cause orlocalization, being catabolic alterations, with synthesis, inhibitionand reparing intent of the cartilage matrix. Metalloproteinases andcytokines (IL-1,IL-6,TNF-α actions promote infl ammatory reactionand cartilage degradation. Pain, the most important symptom,does not correlate with radiologic fi ndings. Peripheral osteoarthritisoccurs predominantly in the knee, hip and hand. Diagnosis is basedon clinical features, laboratorial tests and radiological changes.Rheumatological associations’ guidelines for treatment includenon-pharmacologic (education, physiotherapy, assistive devices,and pharmacologic (analgesics, anti-infl ammatory drugs therapyand surgery. Arthroplasty seems to work better than medicines, butshould be used if other treatments have failed.

  14. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... CME Accreditation PartnerCME Joint Providership Program Verification of Knowledge and Skills Academy of Master Surgeon Educators Academy ... Online Guide to Choosing a Surgical Residency Practice Management Workshops Patients and Family Patient Education Patient Education ...

  15. BUILDING MODEL ANALYSIS APPLICATIONS WITH THE JOINT UNIVERSAL PARAMETER IDENTIFICATION AND EVALUATION OF RELIABILITY (JUPITER) API

    Science.gov (United States)

    The open-source, public domain JUPITER (Joint Universal Parameter IdenTification and Evaluation of Reliability) API (Application Programming Interface) provides conventions and Fortran-90 modules to develop applications (computer programs) for analyzing process models. The input ...

  16. Joint Counterdrug Operations

    Science.gov (United States)

    1998-02-17

    Chapter II Joint Pub 3-07.4 cocaine HCL production. There are over 150 groups trafficking in cocaine, with cartels centered in Medellin and Cali. These...nontraditional mapping products and several digital mapping data bases for geological information and intelligence systems. • Defense Security Assistance Agency...variety of means. Dissemination means include personal contact, physical transfer or courier of hard copy textual and graphic materials, digital and

  17. Jet Joint Undertaking

    International Nuclear Information System (INIS)

    Keen, B.E.; O'Hara, G.W.; Pollard, I.E.

    1988-07-01

    The paper presents the Jet Joint Undertaking annual report 1987. A description is given of the JET and Euratom and International Fusion Programmes. The technical status of JET is outlined, including the development and improvements made to the system in 1987. The results of JET Operation in 1987 are described within the areas of: density effects, temperature improvements, energy confinement studies and other material effects. The contents also contain a summary of the future programme of JET. (U.K.)

  18. Joint Fire Support

    Science.gov (United States)

    2010-06-30

    intelligence application package for theater battle management core system ( TBMCS ) functionality at wing and squadron levels. The automated four... TBMCS , Joint Surveillance and Target Attack Radar System (Ground Control Station), and Global Command and Control System, as well as with Allied FA...The TBMCS is a force level integrated air C2 system. TBMCS provides hardware, software, and communications interfaces to support the preparation

  19. Australias Joint Approach

    Science.gov (United States)

    2015-09-01

    headquarters command and control architecture , including consideration of our suggestion of formalising the strategic J staff system for the support of... architecture … to support successful joint operations.”28 Our analysis involving consultation with a number of senior officers indicates that a more...transported armies into battle since ancient Egyptian times.57 The cooperation between the Royal Australian Navy (RAN) and the Australian Army began with

  20. Working Partnerships: A Joint Venture in Vocational Education.

    Science.gov (United States)

    Campbell, Clifton P.

    Joint Ventures in Vocational Education projects link participating businesses with secondary vocational programs in a cooperative relationship. These are voluntary arrangements between vocational programs and a public or private sector agency that combine the energies and resources of the partners to enrich various aspects of the vocational…

  1. Formation of tough composite joints

    International Nuclear Information System (INIS)

    Brun, M.K.

    1997-05-01

    Joints which exhibit tough fracture behavior were formed in a composite with a Si/SiC matrix reinforced with Textron SCS-6 fibers with either boron nitride or silicon nitride fiber coatings. In composites with BN coatings fibers were aligned uniaxially, while composites with Si 3 N 4 -coated fibers had a 0/90 degree architecture. Lapped joints (joints with overlapping fingers) were necessary to obtain tough behavior. Geometrical requirements necessary to avoid brittle joint failure have been proposed. Joints with a simple overlap geometry (only a few fingers) would have to be very long in order to prevent brittle failure. Typical failure in these joints is caused by a crack propagating along the interfaces between the joint fingers. Joints of the same overall length, but with geometry changed to be symmetric about the joint centerline and with an extra shear surface exhibited tough fractures accompanied with extensive fiber pullout. The initial matrix cracking of these joints was relatively low because cracks propagated easily through the ends of the fingers. Joints with an optimized stepped sawtooth geometry produced composite-like failures with the stress/strain curves containing an elastic region followed by a region of rising stress with an increase of strain. Increasing the fiber/matrix interfacial strength from 9 to 25 MPa, by changing the fiber coating, increased matrix cracking and ultimate strength of the composite significantly. The best joints had matrix cracking stress and ultimate strength of 138 and 240 MPa, respectively. Joint failure was preceded by multiple matrix cracking in the entire composite. The high strength of the joints will permit building of structures containing joints with only a minor reduction of design stresses

  2. Laboratory characterization of rock joints

    International Nuclear Information System (INIS)

    Hsiung, S.M.; Kana, D.D.; Ahola, M.P.; Chowdhury, A.H.; Ghosh, A.

    1994-05-01

    A laboratory characterization of the Apache Leap tuff joints under cyclic pseudostatic and dynamic loads has been undertaken to obtain a better understanding of dynamic joint shear behavior and to generate a complete data set that can be used for validation of existing rock-joint models. Study has indicated that available methods for determining joint roughness coefficient (JRC) significantly underestimate the roughness coefficient of the Apache Leap tuff joints, that will lead to an underestimation of the joint shear strength. The results of the direct shear tests have indicated that both under cyclic pseudostatic and dynamic loadings the joint resistance upon reverse shearing is smaller than that of forward shearing and the joint dilation resulting from forward shearing recovers during reverse shearing. Within the range of variation of shearing velocity used in these tests, the shearing velocity effect on rock-joint behavior seems to be minor, and no noticeable effect on the peak joint shear strength and the joint shear strength for the reverse shearing is observed

  3. Joint Duty Prerequisite for Promotion to 07 (Brigadier General

    Science.gov (United States)

    1989-03-13

    NUMBER)(O LTC Julius E. Coats, Jr. 9. PERFORMING ORGANIZATIN NAME AND ADDRESS I0. PROGRAM ELEMENT. PROJECT. tASK U.S. Army War College AREA 4 WORK...new personnel policy; to wit, the Army leadership at all levels should view joint duty re- quirement for selection for flag officer with a positive...the Army leadership at all levels should view joint duty requirement for selection for flag officer with a positive attitude, not as a means for

  4. Critical joints in large composite primary aircraft structures. Volume 1: Technical summary

    Science.gov (United States)

    Bunin, Bruce L.

    1985-01-01

    A program was conducted at Douglas Aircraft Company to develop the technology for critical joints in composite wing structure that meets all the design requirements of a 1990 commercial transport aircraft. In fulfilling this objective, analytical procedures for joint design and analysis were developed during Phase 1 of the program. Tests were conducted at the element level to supply the empirical data required for methods development. Large composite multirow joints were tested to verify the selected design concepts and for correlation with analysis predictions. The Phase 2 program included additional tests to provide joint design and analysis data, and culminated with several technology demonstration tests of a major joint area representative of a commercial transport wing. The technology demonstration program of Phase 2 is discussed. The analysis methodology development, structural test program, and correlation between test results and analytical strength predictions are reviewed.

  5. Flanged joints with contact outside the bolt circle: ASME Part B design rules

    International Nuclear Information System (INIS)

    Rodabaugh, E.C.; Moore, S.E.

    1976-05-01

    The ASME Boiler and Pressure Vessel Code, Section VIII, Division 1, gives rules which are subdivided into ''Part A'' and ''Part B''. Part A covers flanged joints where contact between flanges occurs through a gasket located inside the bolt holes. Part B covers flanged joints with contact outside the bolt holes. This report (a) summarizes the theory for Part B flanged joints, (b) presents examples which show the significant differences between Part A flanged joints and Part B flanged joints, (c) presents the available test data relevant to the characteristics of Part B flanged joints, (d) gives listings of two computer programs which can be used to evaluate the characteristics of Part B flanged joints, and (e) gives recommendations for Code revisions and other aspects of Part B flanged-joint design

  6. Rapid and sensitive determination of radiocesium (Cs-135, Cs-137) in the presence of excess barium by electrothermal vaporization-inductively coupled plasma-mass spectrometry (ETV-ICP-MS) with potassium thiocyanate as modifier

    International Nuclear Information System (INIS)

    Song, M.; Probst, T.U.; Berryman, N.G.

    2001-01-01

    An electrothermal vaporization-inductively coupled plasma-mass spectrometric (ETV-ICP-MS) method based on selective volatilization of cesium with KSCN as modifier has been developed for determination of radiocesium, i.e. 135 Cs and 137 Cs, in the presence of isobaric barium. A 10000 times excess of barium, which was volatilized at a temperature of 1100 C, resulted only in a 1% signal increase in the signal of mass 135 amu. The recommended concentration of KSCN is 0.3 mM, and pretreatment and volatilization temperatures are 400 C and 1100 C, respectively. A ramp time of 1 s is recommended for the volatilization step. The achieved limit of detection for 135 Cs is 0.2 pg/mL (10 μBq/mL) and 4 fg (0.2 μBq) absolute for a sample volume of 20 μL. This means a limit of detection for 137 Cs of 0.2 pg/mL (0.6 Bq/mL) and of 4 fg (0.01 Bq) absolute. Signal variations of 135 Cs and 137 Cs, respectively, in spiked samples with various matrices were investigated. (orig.)

  7. US/Brazil joint pilot project objectives

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-01

    This paper describes a joint US/Brazil pilot project for rural electrification, whose major goals are: to establish technical, institutional, and economic confidence in using renewable energy (PV and wind) to meet the needs of the citizens of rural Brazil; to establish on-going institutional, individual and business relationships necessary to implement sustainable programs and commitments; to lay the groundwork for larger scale rural electrification through the use of distributed renewable technologies. The projects have supported low power home lighting systems, lighting and refrigeration for schools and medical centers, and water pumping systems. This is viewed as a long term project, where much of the equipment will come from the US, but Brazil will be responsible for program management, and sharing data gained from the program. The paper describes in detail the Brazilian program which was instituted to support this phased project.

  8. The Cost of Jointness: Insights from Environmental Monitoring Systems in Low-Earth Orbit

    Energy Technology Data Exchange (ETDEWEB)

    Dwyer, Morgan Maeve [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2014-09-01

    This report summarizes the results of doctoral research that explored the cost impact of acquiring complex government systems jointly. The report begins by reviewing recent evidence that suggests that joint programs experience greater cost growth than non-joint programs. It continues by proposing an alternative approach for studying cost growth on government acquisition programs and demonstrates the utility of this approach by applying it to study the cost of jointness on three past programs that developed environmental monitoring systems for low-Earth orbit. Ultimately, the report concludes that joint programs' costs grow when the collaborating government agencies take action to retain or regain their autonomy. The report provides detailed qualitative and quantitative data in support of this conclusion and generalizes its findings to other joint programs that were not explicitly studied here. Finally, it concludes by presenting a quantitative model that assesses the cost impacts of jointness and by demonstrating how government agencies can more effectively architect joint programs in the future.

  9. Temporomandibular joint motion

    International Nuclear Information System (INIS)

    Maeda, M.; Kawamura, Y.; Matsuda, T.; Itou, S.; Odori, T.; Ishii, Y.; Torizuka, K.

    1990-01-01

    This paper evaluates MR imaging with the therapeutic effect after splint therapy in internal derangement of the temporomandibular joint (TMJ). Fifteen patients (19 TMJs) with internal derangement of the TMJ and five normal volunteers (10 TMJs) were examined with sagittal T1-weighted spin-echo and gradient recalled acquisition in a steady state (GRASS) MR imaging. MR studies of the patients undergoing splint therapy were performed with an without splints. Pseudodynamic images of TMJ motion provide information that was not available from spin-echo T1-weighted images

  10. Joint Advisory Appeals Board

    CERN Multimedia

    2013-01-01

    The Joint Advisory Appeals Board has examined the internal appeal lodged by a former member of the personnel, a beneficiary of the CERN Pension Fund, against the calculation of his pension in the framework of the Progressive Retirement Programme.   The person concerned has not objected to the report of the Board and the final decision of the Director-General being brought to the attention of the members of the personnel. In application of Article R VI 1.18 of the Staff Regulations, these documents will therefore be available from 26 July to 11 August 2013 at the following link. HR Department Head Office

  11. JOINT ADVISORY APPEALS BOARD

    CERN Multimedia

    Human Resources Division

    2002-01-01

    The Joint Advisory Appeals Board was convened to examine the appeal lodged by Mr Luc Vos with regard to advancement. As the appellant has not objected, the report of the Board and the final decision of the Director-General are brought to the notice of the personnel in accordance with Article R VI 1.20 of the Staff Regulations. The relevant documents will therefore be posted on the notice boards of the Administration Building (N° 60) from 14 to 28 June 2002. Human Resources Division Tel. 74128

  12. Joint Advisory Appeals Board

    CERN Multimedia

    HR Department

    2008-01-01

    The Joint Advisory Appeals Board has examined the internal appeal lodged by a member of the personnel against the decision to grant him only a periodic one-step advancement for the 2006 reference year. The person concerned has not objected to the report of the Board and the final decision of the Director-General being brought to the attention of the members of the personnel. In application of Article R VI 1.18 of the Staff Regulations, these documents will therefore be posted on the notice board of the Main building (bldg. 500) from 1 September to 14 September 2008. Human Resources Department (73911)

  13. Joint Advisory Appeals Board

    CERN Multimedia

    2003-01-01

    The Joint Advisory Appeals Board was convened to examine the appeal lodged by Mr Poul Frandsen concerning his assimilation into the new career structure. As the appellant has not objected, the report of the Board and the final decision of the Director-General are brought to the notice of the personnel in accordance with Article R VI 1.20 of the Staff Regulations. The relevant documents will therefore be posted on the notice boards of the Administration Building (N° 60) from 13 to 24 January 2003. Human Resources Division Tel. 74128

  14. JOINT ADVISORY APPEALS BOARD

    CERN Multimedia

    Personnel Division

    1999-01-01

    The Joint Advisory Appeals Board was convened to examine the appeal lodged by Mr Joào Bento with regard to residential category. As the appellant has not objected, the recommendations of the Board and the final decision of the Director-General are brought to the notice of the personnel in accordance with Article RÊVIÊ1.20 of the Staff Regulations.The relevant documents will therefore be posted on the notice boards of the Administration Building (N¡ 60) from 29 October to 12 November 1999.Personnel DivisionTel. 74128

  15. Joint Advisory Appeals Board

    CERN Multimedia

    HR Department

    2006-01-01

    The Joint Advisory Appeals Board was convened to examine an appeal lodged by a member of the personnel with regard to advancement. The person concerned has requested that the report of the Board and the final decision of the Director-General be brought to the notice of the personnel in accordance with Article R VI 1.20 of the Staff Regulations. The relevant documents will therefore be posted on the notice boards of the Administration Building (No. 60) from 24 March to 10 April 2006. Human Resources Department Tel. 74128

  16. Joint Advisory Appeals Board

    CERN Multimedia

    HR Department

    2007-01-01

    The Joint Advisory Appeals Board was convened to examine an internal appeal lodged by a member of the personnel with regard to the decision not to grant him an indefinite contract. The person concerned has requested that the report of the Board and the final decision of the Director-General be brought to the notice of the members of the personnel, in accordance with Article R VI 1.18 of the Staff Regulations. The relevant documents will therefore be posted on the notice board of the Main building (Bldg. 60) from 24 September to 7 October 2007. Human Resources Department

  17. JOINT ADVISORY APPEALS BOARD

    CERN Multimedia

    Human Resources Division

    2001-01-01

    The Joint Advisory Appeals Board was convened to examine the appeal lodged by Mr Olivier Francis Martin with regard to indefinite contract. As the appellant has not objected, the report of the Board and the final decision of the Director-General are brought to the notice of the personnel in accordance with Article R VI 1.20 of the Staff Regulations. The relevant documents will therefore be posted on the notice boards of the Administration Building (N° 60) from 8 to 25 June 2001.

  18. JOINT ADVISORY APPEALS BOARD

    CERN Multimedia

    Human Resources Division

    2002-01-01

    The Joint Advisory Appeals Board was convened to examine the appeal lodged by Mr Jack Blanchard with regard to 'non recognition of specific functions'. As the appellant has not objected, the report of the Board and the final decision of the Director-General are brought to the notice of the personnel in accordance with Article R VI 1.20 of the Staff Regulations. The relevant documents will therefore be posted on the notice boards of the Administration Building (N° 60) from 12th to 26th April 2002. Human Resources Division Tel. 74128

  19. Joint Advisory Appeals Board

    CERN Multimedia

    2003-01-01

    The Joint Advisory Appeals Board was convened to examine the appeal lodged by Mrs Judith Igo-Kemenes concerning the application of procedures foreseen by Administrative Circular N§ 26 (Rev. 3). As the appellant has not objected, the report of the Board and the final decision of the Director-General are brought to the notice of the personnel in accordance with Article R VI 1.20 of the Staff Regulations. The relevant documents will therefore be posted on the notice boards of the Administration Building (N° 60) from 6 to 20 June 2003. Human Resources Division Tel. 74128

  20. Joint Advisory Appeals Board

    CERN Multimedia

    2004-01-01

    The Joint Advisory Appeals Board was convened to examine the appeal lodged by Mrs Maria DIMOU with regard to a periodic one-step increase. As the appellant has not objected, the report of the Board and the final decision of the Director-General are brought to the notice of the personnel in accordance with Article R VI 1.20 of the Staff Regulations. The relevant documents will therefore be posted on the notice boards of the Administration Building (N° 60) from 30 April to 14 May 2004. Human Resources Department Tel. 74128

  1. JOINT ADVISORY APPEALS BOARD

    CERN Multimedia

    Human Resources Division

    2001-01-01

    The Joint Advisory Appeals Board was convened to examine the appeal lodged by Mr Joël Lahaye with regard to non-resident allowance. As the appellant has not objected, the report of the Board and the final decision of the Director-General are brought to the notice of the personnel in accordance with Article R VI 1.20 of the Staff Regulations. The relevant documents will therefore be posted on the notice boards of the Administration Building (N° 60) from 18 May to 1st June 2001.

  2. Joint Advisory Appeals Board

    CERN Multimedia

    HR Department

    2008-01-01

    The Joint Advisory Appeals Board has examined the internal appeal lodged by a member of the personnel with regard to the decision not to award him a periodic one-step advancement for the 2006 reference year. The person concerned has not objected to the report of the Board and the final decision of the Director-General being brought to the notice of the members of the personnel. In application of Article R VI 1.18 of the Staff Regulations, these documents will therefore be posted on the notice board of the Main building (Bldg. 500) from 17 March to 30 March 2008. Human Resources Department Tel. 73911

  3. JOINT ADVISORY APPEALS BOARD

    CERN Multimedia

    Human Resources Division

    2002-01-01

    The Joint Advisory Appeals Board was convened to examine the appeal lodged by Mr Bertrand Nicquevert with regard to the non-resident allowance. As the appellant has not objected, the report of the Board and the final decision of the Director-General are brought to the notice of the personnel in accordance with Article R VI 1.20 of the Staff Regulations. The relevant documents will therefore be posted on the notice boards of the Administration Building (N° 60) from 29 November to 13 December 2002. Human Resources Division Tel. 74128

  4. JOINT ADVISORY APPEALS BOARD

    CERN Multimedia

    Human Resources Division

    2002-01-01

    The Joint Advisory Appeals Board was convened to examine the appeal lodged by Mr Antonio Millich with regard to advancement. As the appellant has not objected, the report of the Board and the final decision of the Director-General are brought to the notice of the personnel in accordance with Article R VI 1.20 of the Staff Regulations. The relevant documents will therefore be posted on the notice boards of the Administration Building (N° 60) from 27 September to 11 October 2002. Human Resources Division Tel. 74128

  5. Joint Advisory Appeals Board

    CERN Multimedia

    Human Resources Department

    2005-01-01

    The Joint Advisory Appeals Board was convened to examine an appeal lodged by a member of the personnel with regard to a periodic one-step increase. As the appellant has not objected, the report of the Board and the final decision of the Director-General are brought to the notice of the personnel in accordance with Article R VI 1.20 of the Staff Regulations. The relevant documents will therefore be posted on the notice boards of the Administration Building (N° 60) from 1 to 15 April 2005. Human Resources Department Tel. 74128

  6. Joint Advisory Appeals Board

    CERN Multimedia

    HR Department

    2008-01-01

    The Joint Advisory Appeals Board has examined the internal appeal lodged by a member of the personnel against the decision to grant him only a periodic one-step advancement for the 2006 reference year. The person concerned has not objected to the report of the Board and the final decision of the Director-General being brought to the attention of the members of the personnel. In application of Article R VI 1.18 of the Staff Regulations, these documents will therefore be posted on the notice board of the Main Building (Bldg. 500) from 1 September to 14 September 2008. Human Resources Department (73911)

  7. JOINT ADVISORY APPEALS BOARD

    CERN Multimedia

    Human Resources Division

    2002-01-01

    The Joint Advisory Appeals Board was convened to examine the appeal lodged by Mr Gert Jan Bossen with regard to dependent child allowance. As the appellant has not objected, the report of the Board and the final decision of the Director-General are brought to the notice of the personnel in accordance with Article R VI 1.20 of the Staff Regulations. The relevant documents will therefore be posted on the notice boards of the Administration Building (N° 60) from 1st to 15 March 2002. Human Resources Division Tel. 74128

  8. Joint Advisory Appeals Board

    CERN Multimedia

    HR Department

    2008-01-01

    The Joint Advisory Appeals Board has examined the internal appeal lodged by a member of the personnel with regard to the decision not to grant him an indefinite contract. The person concerned has not objected to the report of the Board and the final decision of the Director-General being brought to the notice of the members of the personnel. In application of Article R VI 1.18 of the Staff Regulations, these documents will therefore be posted on the notice board of the Main Building (Bldg. 500) from 26 May to 6 June 2008. Human Resources Department (73911)

  9. JOINT ADVISORY APPEALS BOARD

    CERN Multimedia

    Human Resources Division

    2002-01-01

    The Joint Advisory Appeals Board was convened to examine the appeal lodged by Mr Serge Peraire with regard to exceptional advancement. As the appellant has not objected, the report of the Board and the final decision of the Director-General are brought to the notice of the personnel in accordance with Article R VI 1.20 of the Staff Regulations. The relevant documents will therefore be posted on the notice boards of the Administration Building (N° 60) from 17 to 31 May 2002. Human Resources Division Tel. 74128

  10. Joint Advisory Appeals Board

    CERN Multimedia

    HR Department

    2008-01-01

    The Joint Advisory Appeals Board was convened to examine an internal appeal lodged by a member of the personnel with regard to the decision not to grant him an indefinite contract. The person concerned has not objected to the report of the Board and the final decision of the Director-General being brought to the notice of the members of the personnel, in accordance with Article R VI 1.18 of the Staff Regulations. These documents will therefore be posted on the notice board of the Main Building (Bldg. 60) from 21 January to 3 February 2008. Human Resources Department (73911)

  11. Patellofemoral joint motion

    International Nuclear Information System (INIS)

    Stanford, W.; Phelan, J.; Albright, J.; Kathol, M.; Rooholamini, S.A.; El-Khoury, G.Y.; Palutsis, G.R.

    1988-01-01

    This paper describes the use of ultrafast computed tomography (CT) to obtain dynamic images of the patellofemoral joint during active motion. Thirty-eight patients underwent measurements of tangent offset, bisect offset, congruence angle, patellar tilt angle, lateral patellofemoral angle, sulcus angle, and sulcus depth made during leg movement. Selected parameters were compared with Merchant views. Significant correlations were obtained between Merchant views and comparable ultrafast CT views for all parameters except sulcus angle. Correlations between the other parameters were poor. Cine strips showed two patterns of movement; the patella remained centered either throughout excursion or until the last 20 0 of full extension, when it would sublux laterally

  12. Joint Advisory Appeals Board

    CERN Multimedia

    2003-01-01

    The Joint Advisory Appeals Board was convened to examine the appeal lodged by Mr Aloïs Girardoz with regard to classification and advancement. As the appellant has not objected, the Board's report and the Director-General's decision will be brought to the notice of the personnel in accordance with Article R VI 1.20 of the Staff Regulations. The relevant documents will therefore be posted on the notice boards of the Administration Building (N° 60) from 15 to 29 August 2003. Human Resources Division Tel. 74128

  13. Small Business Programs - The National Guard

    Science.gov (United States)

    Marshal Office of the Joint Surgeon PARC Small Business Programs Chaplain Diversity NGB-GOMO Resources Legislative Liaison Small Business Programs Social Media State Websites Videos Featured Videos On Every Front ARNG Readiness Home : Leadership : Joint Staff : Special Staff : Small Business Programs Small Business

  14. Glenohumeral Joint Injections

    Science.gov (United States)

    Gross, Christopher; Dhawan, Aman; Harwood, Daniel; Gochanour, Eric; Romeo, Anthony

    2013-01-01

    Context: Intra-articular injections into the glenohumeral joint are commonly performed by musculoskeletal providers, including orthopaedic surgeons, family medicine physicians, rheumatologists, and physician assistants. Despite their frequent use, there is little guidance for injectable treatments to the glenohumeral joint for conditions such as osteoarthritis, adhesive capsulitis, and rheumatoid arthritis. Evidence Acquisition: We performed a comprehensive review of the available literature on glenohumeral injections to help clarify the current evidence-based practice and identify deficits in our understanding. We searched MEDLINE (1948 to December 2011 [week 1]) and EMBASE (1980 to 2011 [week 49]) using various permutations of intra-articular injections AND (corticosteroid OR hyaluronic acid) and (adhesive capsulitis OR arthritis). Results: We identified 1 and 7 studies that investigated intra-articular corticosteroid injections for the treatment of osteoarthritis and adhesive capsulitis, respectively. Two and 3 studies investigated the use of hyaluronic acid in osteoarthritis and adhesive capsulitis, respectively. One study compared corticosteroids and hyaluronic acid injections in the treatment of osteoarthritis, and another discussed adhesive capsulitis. Conclusion: Based on existing studies and their level of evidence, there is only expert opinion to guide corticosteroid injection for osteoarthritis as well as hyaluronic acid injection for osteoarthritis and adhesive capsulitis. PMID:24427384

  15. Phytomedicine in Joint Disorders

    Directory of Open Access Journals (Sweden)

    Dorin Dragos

    2017-01-01

    Full Text Available Chronic joint inflammatory disorders such as osteoarthritis and rheumatoid arthritis have in common an upsurge of inflammation, and oxidative stress, resulting in progressive histological alterations and disabling symptoms. Currently used conventional medication (ranging from pain-killers to biological agents is potent, but frequently associated with serious, even life-threatening side effects. Used for millennia in traditional herbalism, medicinal plants are a promising alternative, with lower rate of adverse events and efficiency frequently comparable with that of conventional drugs. Nevertheless, their mechanism of action is in many cases elusive and/or uncertain. Even though many of them have been proven effective in studies done in vitro or on animal models, there is a scarcity of human clinical evidence. The purpose of this review is to summarize the available scientific information on the following joint-friendly medicinal plants, which have been tested in human studies: Arnica montana, Boswellia spp., Curcuma spp., Equisetum arvense, Harpagophytum procumbens, Salix spp., Sesamum indicum, Symphytum officinalis, Zingiber officinalis, Panax notoginseng, and Whitania somnifera.

  16. Joint resistance measurements of pancake and terminal joints for JT-60SA EF coils

    Energy Technology Data Exchange (ETDEWEB)

    Obana, Tetsuhiro, E-mail: obana.tetsuhiro@LHD.nifs.ac.jp [National Institute for Fusion Science, 322-6 Oroshi, Toki, Gifu 509-5292 (Japan); Takahata, Kazuya; Hamaguchi, Shinji; Mito, Toshiyuki; Imagawa, Shinsaku [National Institute for Fusion Science, 322-6 Oroshi, Toki, Gifu 509-5292 (Japan); Kizu, Kaname; Murakami, Haruyuki; Yoshida, Kiyoshi [Japan Atomic Energy Agency, 801-1 Mukoyama, Naka, Ibaraki 311-0193 (Japan)

    2013-11-15

    Highlights: • To evaluate the joint fabrication technology for the JT-60SA EF coils, joint resistance measurements were conducted with a joint sample. • The joint sample was composed of pancake and terminal joints. • The measurements demonstrated that both joints fulfilled the design requirement. • Considering the measurements, the characteristics of both joints were investigated using an analytical model that represents the joints. -- Abstract: To evaluate the joint fabrication technology for the JT-60SA EF coils, joint resistance measurements were conducted using a sample consisting of pancake and terminal joints. Both joints are shake-hands lap joints composed of cable-in-conduit conductors and a pure copper saddle-shaped spacer. The measurements demonstrated that both joints fulfilled the design requirement. Considering these measurements, the characteristics of both joints were investigated using analytical models that represent the joints. The analyses indicated that the characteristics of the conductors used in the joints affect the characteristics of the joints.

  17. Radiosynoviorthesis in haemaphilic joint disease

    International Nuclear Information System (INIS)

    Pad Bosch, P.J.I. van't; Putte, L.B.A. van de; Boerbooms, A.M.T.; Geerdink, P.J.

    1981-01-01

    The effects of radiosynoviorthesis on chronic haemophilic arthropathic joints were studied in six patients with severe haemophilia by a follow up study which spanned two and a half years. On clinical grounds the treatment was successful because pain and bleeding frequency diminished, although radiographic examination showed further deterioration of the treated joint. Chromosome damage was not detected. We conclude that radiosynoviorthesis is apparently changing the bleeding pattern of articular tissues without arresting the destruction and deformation of joints. (orig.) [de

  18. Leveraging Technology for Joint Training

    National Research Council Canada - National Science Library

    Walker, Jack

    1997-01-01

    .... While this innovation will have a significant impact on education and training, it will not fulfill its potential unless joint and component commanders understand what the technologies represent...

  19. Joint Small Arms Technology Development Strategy for Joint Service Small Arms Science and Technology Investments

    Science.gov (United States)

    2016-01-26

    reduction efforts that need to be led by the Joint Services include One Way Luminescence, where the improvement in hit goes up for the follow on shots...new technology would enable spectral segment defeat, ranging from ultraviolet ( UV ), visible, Infrared (IR), radar, and radio and any combinations...program of work as directed via the Land Armaments Management Plan ( LAMP ) and advise the NAAG on systems and equipment aspects of dismounted operations

  20. Strengthening of defected beam–column joints using CFRP

    Directory of Open Access Journals (Sweden)

    Mohamed H. Mahmoud

    2014-01-01

    Full Text Available This paper presents an experimental study for the structural performance of reinforced concrete (RC exterior beam–column joints rehabilitated using carbon-fiber-reinforced polymer (CFRP. The present experimental program consists of testing 10 half-scale specimens divided into three groups covering three possible defects in addition to an adequately detailed control specimen. The considered defects include the absence of the transverse reinforcement within the joint core, insufficient bond length for the beam main reinforcement and inadequate spliced implanted column on the joint. Three different strengthening schemes were used to rehabilitate the defected beam–column joints including externally bonded CFRP strips and sheets in addition to near surface mounted (NSM CFRP strips. The failure criteria including ultimate capacity, mode of failure, initial stiffness, ductility and the developed ultimate strain in the reinforcing steel and CFRP were considered and compared for each group for the control and the CFRP-strengthened specimens. The test results showed that the proposed CFRP strengthening configurations represented the best choice for strengthening the first two defects from the viewpoint of the studied failure criteria. On the other hand, the results of the third group showed that strengthening the joint using NSM strip technique enabled the specimen to outperform the structural performance of the control specimen while strengthening the joints using externally bonded CFRP strips and sheets failed to restore the strengthened joints capacity.

  1. Strengthening of defected beam-column joints using CFRP.

    Science.gov (United States)

    Mahmoud, Mohamed H; Afefy, Hamdy M; Kassem, Nesreen M; Fawzy, Tarek M

    2014-01-01

    This paper presents an experimental study for the structural performance of reinforced concrete (RC) exterior beam-column joints rehabilitated using carbon-fiber-reinforced polymer (CFRP). The present experimental program consists of testing 10 half-scale specimens divided into three groups covering three possible defects in addition to an adequately detailed control specimen. The considered defects include the absence of the transverse reinforcement within the joint core, insufficient bond length for the beam main reinforcement and inadequate spliced implanted column on the joint. Three different strengthening schemes were used to rehabilitate the defected beam-column joints including externally bonded CFRP strips and sheets in addition to near surface mounted (NSM) CFRP strips. The failure criteria including ultimate capacity, mode of failure, initial stiffness, ductility and the developed ultimate strain in the reinforcing steel and CFRP were considered and compared for each group for the control and the CFRP-strengthened specimens. The test results showed that the proposed CFRP strengthening configurations represented the best choice for strengthening the first two defects from the viewpoint of the studied failure criteria. On the other hand, the results of the third group showed that strengthening the joint using NSM strip technique enabled the specimen to outperform the structural performance of the control specimen while strengthening the joints using externally bonded CFRP strips and sheets failed to restore the strengthened joints capacity.

  2. Temporomandibular joint movement

    International Nuclear Information System (INIS)

    Maeda, M.; Itou, S.; Ishii, Y.; Yamamoto, K.; Kawamura, Y.; Matsuda, T.; Hayashi, N.; Ishii, J.

    1992-01-01

    Ten temporomandibular joints (TMJs) of 5 healthy volunteers and 19 TMJs of internal derangements in 16 patients with splint therapy were examined with MR imaging. T1-weighted images were obtained only in the closed mouth position, and gradient recalled acquisition in steady state (GRASS) images were obtained in active opening and closing phases, allowing a pseudodynamic display of TMJ movement. All patients received protrusive splint treatment. The usefulness of MR imaging to assess the efficacy of splint therapy was evaluated. Corrected disk position with the splint in place was clearly demonstrated in 9 TMJs, corresponding with elimination of reciprocal clicking. Ten other TMJs of anterior disk displacement without reduction showed uncorrected disk position by the splint. This information could confirm the therapeutic efficacy, or suggest other treatment alternatives. GRASS MR imaging can provide accurate and physiologic information about disk function in initial and follow-up assessment of protrusive splint therapy. (orig.)

  3. JOINT ADVISORY APPEALS BOARD

    CERN Multimedia

    Human Resources Division

    2001-01-01

    The Joint Advisory Appeals Board was convened to examine the appeal lodged by Mr Neil Calder, Mrs Sudeshna Datta Cockerill, Mrs Andrée Fontbonne, Mrs Moniek Laurent and Mr Ulrich Liptow with regard to membership in the Pension Fund under the period with a Paid Associate contract, appeals dealt with on a collective basis. As the appellants have not objected, the report of the Board and the final decision of the Director-General are brought to the notice of the personnel in accordance with Article R VI 1.20 of the Staff Regulations. The relevant documents will therefore be posted on the notice boards of the Administration Building (N° 60) from 10 to 31 August 2001.

  4. Temporomandibular joint arthrography

    International Nuclear Information System (INIS)

    Choi, Hyung Sik; Lee, Kyung Soo; Kim, Myoung Joon; Jun, Young Hwan; Chang, Duk Soo; Jung, Don Young; Jung, In Won

    1988-01-01

    The stress and occlusion disturbance are very important etiologic factors in the temporomandibular joint (TMJ) pain dysfunction syndromes. Authors performed TMJ arthrograms in the patients with TMJ problem such as pain, click sound, limited motion and locking, etc. The following results noted: 1. The arthrographic findings of 22 TMJ were analyzed. a) Normal: 6 cases b) Anterior disc displacement with rediction: 6 cases · Early reduction: 2 cases · Intermediate reduction: 3 cases · Late reduction: 1 case c) Anterior disc displacement without reduction: 6 cases · Two cases had adhesion between the posterior portion of disc and the posterior surfaces of the articular eminence. 2. Among 22 cases, the clinical findings of 16 cases (73%) were compatible with arthrographic findings. 6 cases showed disparity between them.

  5. Sacroiliac joint: A review

    Directory of Open Access Journals (Sweden)

    Khushali Tilvawala

    2018-01-01

    Full Text Available Sacroiliac joint (SIJ pain is one of the common but underdiagnosed source of mechanical low back pain. The incidence is estimated to be in the range of 15%–30% in patients with nonradicular low back pain. The signs and symptoms of SIJ pain mimic pain arising from other causes of low back pain. There is no single symptom or physical examination finding that can firmly diagnose SIJ as a source of patient's pain. There is good evidence suggesting that a combination of three or more positive provocative tests strongly suggests SIJ dysfunction. Intra-articular injection with local anesthetic is considered the gold standard for diagnosis of SIJ pain. Many treatment modalities are available for SIJ pain, ranging from conservative management to surgical interventions. This review article covers all the aspects of SIJ pain, with treatment section mainly covering evidence-based interventional procedures.

  6. Development of design and analysis methodology for composite bolted joints

    Science.gov (United States)

    Grant, Peter; Sawicki, Adam

    1991-05-01

    This paper summarizes work performed to develop composite joint design methodology for use on rotorcraft primary structure, determine joint characteristics which affect joint bearing and bypass strength, and develop analytical methods for predicting the effects of such characteristics in structural joints. Experimental results have shown that bearing-bypass interaction allowables cannot be defined using a single continuous function due to variance of failure modes for different bearing-bypass ratios. Hole wear effects can be significant at moderate stress levels and should be considered in the development of bearing allowables. A computer program has been developed and has successfully predicted bearing-bypass interaction effects for the (0/+/-45/90) family of laminates using filled hole and unnotched test data.

  7. Fiscal 1993 international joint projects under New Sunshine Program. Surveys of bilateral cooperation and solar energy technology; 1993 nendo kokusai kyoryoku jigyo nikokukan kyoryoku taiyo energy gijutsu ni kakawaru gijutsu chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-03-01

    Concerning bilateral projects, overseas surveys were conducted about Japan-Australian and Japan-US technical cooperation. Concerning technological development, information was collected at the Solar World Congress of the International Solar Energy Society (ISES), and information was collected and opinions were exchanged at the 15th International Conference on Amorphous Semiconductors. A survey was conducted of Russia's development of solar cells and of their performance evaluation, and an overseas survey was conducted of the development of spaceborne photovoltaic power generation system practicalization technology. Surveys were conducted of international joint projects for the development of photovoltaic power generation system practicalization technology in Europe and the US. Overseas surveys were conducted of international joint projects concerning the development of photovoltaic power generation system practicalization technology, and a survey was conducted of the research and development of photovoltaic power generation in the US and of the state of introduction and diffusion of the same. A survey was also conducted of the state of element technology development for solar energy utilization in Europe. (NEDO)

  8. Fiscal 1999 research report. Basic research for promotion of joint implementation programs (Basic energy efficiency survey at Russia's Severstal Steelworks); 1999 nendo Russia Severstal seitetsusho sho energy kihon chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    In the Kyoto Protocol adopted at COP3 (The 3rd Conference of the Parties), a framework was created of international cooperative efforts for greenhouse gas reduction, such as joint implementation with advanced countries and clean development mechanism construction with developing countries. As part of the above-named NEDO-sponsored project, a survey is conducted at the Severstal Steelworks in the effort to explore projects that will lead to joint implementation. It is then found, concerning the feasibility of introducing large waste heat recovery and energy-saving facilities into the steelworks, that there will be sufficient room if natural gas for the domestic power generators installed at two sites in the steelworks is reduced and that in the energy profile no problems are detected that will impede project implementation. Energy efficiency measure introduction feasibility is examined and the results are shown, which involve sintering furnace modification, sintering cooler waste heat recovery, converter exhaust gas recovery, and TRT (top-pressure recovery turbine) installation. In case all these measure are fully implemented, CO2 emissions will be reduced by 370,000 tons/year. (NEDO)

  9. Fiscal 1993 international joint projects under New Sunshine Program. Surveys of bilateral cooperation and solar energy technology; 1993 nendo kokusai kyoryoku jigyo nikokukan kyoryoku taiyo energy gijutsu ni kakawaru gijutsu chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-03-01

    Concerning bilateral projects, overseas surveys were conducted about Japan-Australian and Japan-US technical cooperation. Concerning technological development, information was collected at the Solar World Congress of the International Solar Energy Society (ISES), and information was collected and opinions were exchanged at the 15th International Conference on Amorphous Semiconductors. A survey was conducted of Russia's development of solar cells and of their performance evaluation, and an overseas survey was conducted of the development of spaceborne photovoltaic power generation system practicalization technology. Surveys were conducted of international joint projects for the development of photovoltaic power generation system practicalization technology in Europe and the US. Overseas surveys were conducted of international joint projects concerning the development of photovoltaic power generation system practicalization technology, and a survey was conducted of the research and development of photovoltaic power generation in the US and of the state of introduction and diffusion of the same. A survey was also conducted of the state of element technology development for solar energy utilization in Europe. (NEDO)

  10. Medicare Program; Cancellation of Advancing Care Coordination Through Episode Payment and Cardiac Rehabilitation Incentive Payment Models; Changes to Comprehensive Care for Joint Replacement Payment Model: Extreme and Uncontrollable Circumstances Policy for the Comprehensive Care for Joint Replacement Payment Model. Final rule; interim final rule with comment period.

    Science.gov (United States)

    2017-12-01

    This final rule cancels the Episode Payment Models (EPMs) and Cardiac Rehabilitation (CR) Incentive Payment Model and rescinds the regulations governing these models. It also implements certain revisions to the Comprehensive Care for Joint Replacement (CJR) model, including: Giving certain hospitals selected for participation in the CJR model a one-time option to choose whether to continue their participation in the model; technical refinements and clarifications for certain payment, reconciliation and quality provisions; and a change to increase the pool of eligible clinicians that qualify as affiliated practitioners under the Advanced Alternative Payment Model (Advanced APM) track. An interim final rule with comment period is being issued in conjunction with this final rule in order to address the need for a policy to provide some flexibility in the determination of episode costs for providers located in areas impacted by extreme and uncontrollable circumstances.

  11. Arthroscopy of the ankle joint

    NARCIS (Netherlands)

    van Dijk, C. N.; Scholte, D.

    1997-01-01

    Ankle arthroscopy has become a standard procedure for a variety of indications. Joint distraction is applied by many authors. A recent retrospective multicentre study provoked the following questions. Is there an indication for diagnostic arthroscopy? Can arthroscopic surgery of the ankle joint be

  12. From joint to single audits

    DEFF Research Database (Denmark)

    Holm, Claus; Thinggaard, Frank

    2018-01-01

    This study analyses audit quality differences between audits by a single big audit firm and joint audits with either one or two big audit firms. We exploit the unique situation in Denmark beginning on 1 January 2005, at which time a long-standing mandatory joint audit system for listed companies ...

  13. IMPLEMENTATION OF ESG FOR INTERNATIONAL JOINT EDUCATION PROGRAMMES

    Directory of Open Access Journals (Sweden)

    Vera I. Zabotkina

    2016-12-01

    Full Text Available Introduction: joint international programmes stimulate staff and student mobility, provide joint studies, provide development of joint study programmes of excellence, and open up new possibilities for cooperation between countries. Promotion and development of joint international programmes depend on effective quality assurance system which is high on the universities` priority list. ESG provide solid basis for the quality assurance system development at both institutional and programme levels. The problems of ESG interpretation in compliance with national legislative systems and education traditions in the countries participating in Bologna process are paid much attention to. Our emphases are on the practical aspects of ESG (2015 version implementation. The article concentrates on one of the most acute problems facing Russian Higher Education Institutions in the field of development and promotion of joint international programs: the problem of setting up modern quality assurance systems compatible with those in European HEIs is closely correlating with the profile of the journal “Integration of Education”. The journal centers around the publications on the enhancement and dissemination of the best practices on integration of regional education in Russia and abroad. Materials and Methods: methodical and practical aspects of the implementation of the ESG provisions for international joint educational programs on the basis of the European approach to education quality are the materials of study. The descriptive method, analysis of documents about education quality, and synthesis were used as research methods. Results: the authors come up with concrete recommendations for the implementation of the ESG renewed version (2015 in Quality Assurance systems of joint international programmes. This approach enhances the practical value of ESG. Modern Quality Assurance system is one of the main prerequisites for the successful collaboration among higher

  14. Transition joints in INDUS-2

    International Nuclear Information System (INIS)

    Sridhar, R.; Amalraj, William; Shukla, S.K.; Jain, A.K.

    2003-01-01

    Full text: A large number of welding joints are being employed in the fabrication of Indus-2 synchrotron storage ring being constructed at CAT. Apart from the TIG welded joints of aluminium alloy vacuum chambers, there are many other joints which are made between dissimilar metals. Stainless steel pipes are friction welded with aluminium pipes and are to be used as pumping ducts between vacuum pumps and the vacuum chambers. Similarly stainless steel flanges are fastened with aluminium flanges through a diamond seal. These joints are tested for a leak tightness of 2 x 10 -10 torr lit/sec of helium. This paper describes the details of the friction welded joints and their application in the Indus-2 synchrotron storage ring

  15. Induction brazing of complex joints

    DEFF Research Database (Denmark)

    Henningsen, Poul; Zhang, Wenqi; Bay, Niels

    2003-01-01

    , or if the hottest area is located outside the joint interface, a number of defects may appear: the braze metal may flow away from the joint, the flux may burn off, poor binding of the braze metal may appear or the braze metal may be overheated. Joint geometry as well as electro-magnetic properties of the work piece...... presents a combined numerical and experimental method for fast determination of appropriate coil geometry and position in induction brazing tube-to-plate joints of different ratios between tube and plate thickness and different combinations of the materials stainless steel, brass and copper. The method has...... proven to give successful results in brazing tube-plate joints of copper-brass, copper-stainless steel, stainless steel-brass, and stainless steel-stainless steel....

  16. Space Station alpha joint bearing

    Science.gov (United States)

    Everman, Michael R.; Jones, P. Alan; Spencer, Porter A.

    1987-01-01

    Perhaps the most critical structural system aboard the Space Station is the Solar Alpha Rotary Joint which helps align the power generation system with the sun. The joint must provide structural support and controlled rotation to the outboard transverse booms as well as power and data transfer across the joint. The Solar Alpha Rotary Joint is composed of two transition sections and an integral, large diameter bearing. Alpha joint bearing design presents a particularly interesting problem because of its large size and need for high reliability, stiffness, and on orbit maintability. The discrete roller bearing developed is a novel refinement to cam follower technology. It offers thermal compensation and ease of on-orbit maintenance that are not found in conventional rolling element bearings. How the bearing design evolved is summarized. Driving requirements are reviewed, alternative concepts assessed, and the selected design is described.

  17. BAGHOUSE FILTRATION PRODUCTS VERIFICATION TESTING, HOW IT BENEFITS THE BOILER BAGHOUSE OPERATOR

    Science.gov (United States)

    The paper describes the Environmental Technology Verification (ETV) Program for baghouse filtration products developed by the Air Pollution Control Technology Verification Center, one of six Centers under the ETV Program, and discusses how it benefits boiler baghouse operators. A...

  18. EFFECT OF HEEL LIFTS ON PATELLOFEMORAL JOINT STRESS DURING RUNNING.

    Science.gov (United States)

    Mestelle, Zachary; Kernozek, Thomas; Adkins, Kelly S; Miller, Jessica; Gheidi, Naghmeh

    2017-10-01

    Patellofemoral pain is a debilitating injury for many recreational runners. Excessive patellofemoral joint stress may be the underlying source of pain and interventions often focus on ways to reduce patellofemoral joint stress. Heel lifts have been used as an intervention within Achilles tendon rehabilitation programs and to address leg length discrepancies. The purpose of this study was to examine the effect of running with heel lifts on patellofemoral joint stress, patellofemoral stress impulse, quadriceps force, step length, cadence, and other related kinematic and spatiotemporal variables. A repeated-measures research design. Sixteen healthy female runners completed five running trials in a controlled laboratory setting with and without 11mm heel lifts inserted in a standard running shoe. Kinetic and kinematic data were used in combination with a static optimization technique to estimate individual muscle forces. These data were inserted into a patellofemoral joint model which was used to estimate patellofemoral joint stress and other variables during running. When running with heel lifts, peak patellofemoral joint stress and patellofemoral stress impulse were reduced by a 4.2% (p=0.049) and 9.3% (p=0.002). Initial center of pressure was shifted anteriorly 9.1% when running with heel lifts (p0.05) were shown between conditions. Heel lift use resulted in decreased patellofemoral joint stress and impulse without associated changes in step length or frequency, or other variables shown to influence patellofemoral joint stress. The center of pressure at initial contact was also more anterior using heel lifts. The use of heel lifts may have therapeutic benefits for runners with patellofemoral pain if the primary goal is to reduce patellofemoral joint stress. 3b.

  19. US initiative on joint implementation: An overview

    Energy Technology Data Exchange (ETDEWEB)

    Dixon, R.K. [Initiative on Joint Implementation, Washington, DC (United States)

    1996-12-31

    More than 150 countries are now Party to United Nations Framework Convention on Climate Change, which seeks as its ultimate objective, to stabilize atmospheric concentrations of greenhouse gases at a level that would prevent dangerous human interference with the global climate system. As a step towards that goal, all Parties are to take measures to mitigate greenhouse gas emissions and to promote cooperation in the development and diffusion of technologies and practices that control or reduce emissions and enhance sinks of greenhouse gases. In the U.S. view, efforts between countries or entities within them to reduce net greenhouse gas emissions undertaken cooperatively, termed joint implementation (JI), holds significant potential both for reducing the threat of global climate change and for promoting sustainable development. To develop and operationalize the JI concept, the U.S. launched its Initiative on Joint Implementation (IJI) in October, 1993, and designed a program to attract private sector resources and to encourage the diffusion of innovative technologies to mitigate greenhouse gas emissions. The goals of U.S. IJI complement the principles of Decision 5, First Conference of the FCCC Parties, establishing an Activities Implemented Jointly pilot phase.

  20. Joint implementation: Biodiversity and greenhouse gas offsets

    Science.gov (United States)

    Cutright, Noel J.

    1996-11-01

    One of the most pressing environmental issues today is the possibility that projected increases in global emissions of greenhouse gases from increased deforestation, development, and fossil-fuel combustion could significantly alter global climate patterns. Under the terms of the United Nations Framework Convention on Climate Change, signed in Rio de Janeiro during the June 1992 Earth Summit, the United States and other industrialized countries committed to balancing greenhouse gas emissions at 1990 levels in the year 2000. Included in the treaty is a provision titled “Joint Implementation,” whereby industrialized countries assist developing countries in jointly modifying long-term emission trends, either through emission reductions or by protecting and enhancing greenhouse gas sinks (carbon sequestration). The US Climate Action Plan, signed by President Clinton in 1993, calls for voluntary climate change mitigation measures by various sectors, and the action plan included a new program, the US Initiative on Joint Implementation. Wisconsin Electric decided to invest in a Jl project because its concept encourages creative, cost-effective solutions to environmental problems through partnering, international cooperation, and innovation. The project chosen, a forest preservation and management effort in Belize, will sequester more than five million tons of carbon dioxide over a 40-year period, will become economically selfsustaining after ten years, and will have substantial biodiversity benefits.

  1. Work in Progress - Developing Joint Degrees through E-Learning Systems

    OpenAIRE

    Aguirre Herrera, Sandra; Quemada Vives, Juan; Salvachúa Rodríguez, Joaquín

    2008-01-01

    The development of Joint Degrees is an important mechanism for opening higher education systems nationwide, adapting them to the international standard, and promoting quality assessment to a broader environment. Since e-Learning systems covers a wide range of academic programs, and as joint degrees such as e-Learning are rapidly growing trends, finding a suitable solution that enables universities to design joint degrees through their own e-Learning systems becomes necessary. This paper intro...

  2. Airborne and Maritime/Fixed Station Joint Tactical Radio System (AMF JTRS)

    Science.gov (United States)

    2015-12-01

    Selected Acquisition Report (SAR) RCS: DD-A&T(Q&A)823-421 Airborne & Maritime/Fixed Station Joint Tactical Radio System (AMF JTRS) As of FY 2017...Information Program Name Airborne & Maritime/Fixed Station Joint Tactical Radio System (AMF JTRS) DoD Component Army Responsible Office References SAR...UNCLASSIFIED 5 Mission and Description Airborne & Maritime/Fixed Station Joint Tactical Radio System (AMF JTRS) products are software programmable

  3. Determination of the spatial movement of the temporomandibular joints (tmj joint heads in patients with muscle and joint dysfunction according to computed tomography (ct

    Directory of Open Access Journals (Sweden)

    Аркадий Максимович Боян

    2015-11-01

    Full Text Available Computed tomography (CT is the one of most objective diagnostic methods of TMJ MJD it allows define amplitudes of joint heads movement in sagittal projections to detect an asymmetry of TMJ elements location.Aim of research. Assessment of location of mandibular joint heads and determination of its spatial position in patients with TMJ MJD before treatment and after it using CT.Materials and methods. 50 patients 28-62 years old, 37 women and 13 men who underwent computed tomography (CT of TMJ were under observation.The results of observation were analyzed in details.The studies were carried out using cone-radial computed tomographic scanner «Vatech Pax uni 3d». CT of TMJ was carried out in habitual occlusion before the start of treatment and after removal of TMJ MJD symptoms and complaints. At the study there were measured the width of joint fissure in front, upper and back segments according to N.A. Rabuhina methodology in N.E. Androsova and so-authors modification. Statistical analysis of the data received was carried out using «Statistics» (Statsoft, Inc program.Results. The results of TMJ CT in patients before the start of treatment demonstrated that the sizes of TMJ joint fissure were different. The width of the upper segment of TMJ joint fissure in patients before the start of treatment was reliably less (≤0,001 comparing with an analogous parameter in the group of patients after treatment that indicates the upper location of mandibular head in TMJ with reducing the height of the lower segment of face.So the data of study of the joint fissure width received using TMJ CT demonstrate formation of specific outlines of joint fissure at displacement of mandible and consequently joint head. Information about the joint fissure parameters allows rationally plan and realize orthopedic treatment and the necessary rehabilitation measures in patients with TMJ MJD.Conclusions. The studies demonstrated that the displacements of mandibular joint

  4. Joint action aesthetics.

    Science.gov (United States)

    Vicary, Staci; Sperling, Matthias; von Zimmermann, Jorina; Richardson, Daniel C; Orgs, Guido

    2017-01-01

    Synchronized movement is a ubiquitous feature of dance and music performance. Much research into the evolutionary origins of these cultural practices has focused on why humans perform rather than watch or listen to dance and music. In this study, we show that movement synchrony among a group of performers predicts the aesthetic appreciation of live dance performances. We developed a choreography that continuously manipulated group synchronization using a defined movement vocabulary based on arm swinging, walking and running. The choreography was performed live to four audiences, as we continuously tracked the performers' movements, and the spectators' affective responses. We computed dynamic synchrony among performers using cross recurrence analysis of data from wrist accelerometers, and implicit measures of arousal from spectators' heart rates. Additionally, a subset of spectators provided continuous ratings of enjoyment and perceived synchrony using tablet computers. Granger causality analyses demonstrate predictive relationships between synchrony, enjoyment ratings and spectator arousal, if audiences form a collectively consistent positive or negative aesthetic evaluation. Controlling for the influence of overall movement acceleration and visual change, we show that dance communicates group coordination via coupled movement dynamics among a group of performers. Our findings are in line with an evolutionary function of dance-and perhaps all performing arts-in transmitting social signals between groups of people. Human movement is the common denominator of dance, music and theatre. Acknowledging the time-sensitive and immediate nature of the performer-spectator relationship, our study makes a significant step towards an aesthetics of joint actions in the performing arts.

  5. Joint seal in tank

    International Nuclear Information System (INIS)

    Colquhoun, J.; White, G.V.

    1981-01-01

    A seal for a joint or gap between edges of adjacent wall sections (e.g. of concrete) of a liquid-containing vessel, such as a nuclear reactor cooling pond, comprises a sheet metal strip having longitudinally-extending edge parts, secured to the respective vessel-section edges, and a central part which is longitudinally corrugated to provide sufficient flexibility to accommodate slight relative movements between the vessel-section edges (e.g. due to thermal expansions). The edges of the sheet metal of the strip are turned in so that the edge parts of the strip are formed as generally U-section channels. These accommodate longitudinally extending securing bars which are bolted to the vessel wall sections by bolts which pass through the bars, through the free-edged wall of the channel section and through a longitudinally extending resilient seal pad compressed between that wall of the channel section and the vessel wall section to which it is secured. The other wall of the channel section (integral with the corrugated central part of the strip) has access windows through which the bolts are inserted and tightened, the windows being then closed off in liquid-tight manner by welding closure caps over them. (author)

  6. Temporomandibular Joint Regenerative Medicine

    Directory of Open Access Journals (Sweden)

    Xavier Van Bellinghen

    2018-02-01

    Full Text Available The temporomandibular joint (TMJ is an articulation formed between the temporal bone and the mandibular condyle which is commonly affected. These affections are often so painful during fundamental oral activities that patients have lower quality of life. Limitations of therapeutics for severe TMJ diseases have led to increased interest in regenerative strategies combining stem cells, implantable scaffolds and well-targeting bioactive molecules. To succeed in functional and structural regeneration of TMJ is very challenging. Innovative strategies and biomaterials are absolutely crucial because TMJ can be considered as one of the most difficult tissues to regenerate due to its limited healing capacity, its unique histological and structural properties and the necessity for long-term prevention of its ossified or fibrous adhesions. The ideal approach for TMJ regeneration is a unique scaffold functionalized with an osteochondral molecular gradient containing a single stem cell population able to undergo osteogenic and chondrogenic differentiation such as BMSCs, ADSCs or DPSCs. The key for this complex regeneration is the functionalization with active molecules such as IGF-1, TGF-β1 or bFGF. This regeneration can be optimized by nano/micro-assisted functionalization and by spatiotemporal drug delivery systems orchestrating the 3D formation of TMJ tissues.

  7. Fiscal 1999 report on basic research for promotion of joint implementation programs. Gas pipeline system optimization involving Ukrainian pipeline modification for reduction in global warming gas emissions; 1999 nendo ondanka gas haishutsu sakugen no tame no Ukraina ni okeru gas pipeline no kaishu wo fukumu pipeline system no saitekika chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    The result of a survey which involves a 520km-long gas pipeline (Shebelinka-Dikanka-Kyiv) modification in the Ukraine is described, which will promote joint implementation programs under COP3 (Third Session of the Conference of the Parties to the United Nations Framework Convention on Climate Change). Since the greenhouse effect of methane gas is 21 times as serious as that of CO2, it is important to ensure good maintenance and structural soundness for natural gas transporting pipeline systems. The currently available Ukrainian gas turbines and compressors are so obsolescent that their efficiency rate is as low as 23%. The rate will rise to 36% when the old ones are replaced by high power equipment capable of high efficiency combustion. Pipelines will be checked for deterioration due to stress corrosion cracking and dangerous pipes will be replaced, with attention paid particularly to joint sections. It is expected that there will be a greenhouse gas reduction of 512,000 tons (in terms of CO2) and a saving of 103,000 tons on fuel (in terms of crude). Balance is tentatively estimated in case the expected reduction in emissions is transacted in emission trading. Profitability will occur, in view of profit from emission trading and gas sales revenue after gas leakage prevention thanks to project implementation, when the emission right sells at 30 dollars/ton or higher. The rippling effect will be great now that the Ukrainian pipeline system is quite extensive (with 30% thereof superannuated). (NEDO)

  8. Joint annual report 1981

    International Nuclear Information System (INIS)

    Hohmuth, K.

    1982-10-01

    Results of research work carried out at the ZfK Rossendorf and other scientific institutions of the GDR in 1981 are presented in individual summaries covering the following topics: nuclear reactions, nuclear spectroscopy, nuclear theory, applied methods of nuclear physics, accelerators, nuclear electronics, computer programs. A list of publications is included

  9. Joint Sustainment of Weapon Systems. Would We Be Better Off?

    National Research Council Canada - National Science Library

    Hall, Richard A

    2006-01-01

    .... As depots within the military begin to implement new procedures based on the Lean Six Sigma model, a proposed consolidation of efforts based on major weapon systems could lead to improved cost benefits and decreased maintenance time. Tied with the current Joint Depot Maintenance Program, Lean Six Sigma can continue to improve the Service's depot performance.

  10. Simulation of Hooke's Joint on the Analog Computer.

    Science.gov (United States)

    Mitchell, Eugene E., Ed.

    1980-01-01

    A problem is presented that teaches the engineering student or practicing engineer the behavior of Hooke's joint, a widely used mechanism for transmitting rotary power in mechanical equipment. Also provided by this problem is an exercise in analog programing which utilizes nonlinear computer elements. (Author/CS)

  11. The National Guard: Recommendations to Develop the Joint Future Force

    Science.gov (United States)

    2010-03-01

    Health, Sexual Assault Prevention and Response, and Warrior Support programs.109 This joint support concept is distinctive to the NG, and provides an...National Defense Strategy (Washington, DC: Department of Defense, June 2008), TOC . Available online at http://www.defense.gov/news/2008%20 National

  12. Joint Optimization of Working and p-cycle Protection Capacity

    DEFF Research Database (Denmark)

    Stidsen, Thomas K.; Thomadsen, Tommy

    2004-01-01

    -cycles are significantly more efficient than rings and comparable to any meshed protection method. The results also show that substantial savings can be achieved when routing and protection is performed jointly as compared to when it is not. Based on the integer linear programming model, we discuss how protection costs...

  13. 76 FR 19188 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Science.gov (United States)

    2011-04-06

    ... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical... the panels of the Joint Biomedical Laboratory Research and Development and Clinical Science Research.... Neurobiology-D June 10, 2011 Crowne Plaza DC/Silver Spring. Clinical Research Program June 13, 2011 VA Central...

  14. 75 FR 57833 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Science.gov (United States)

    2010-09-22

    ... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical... the panels of the Joint Biomedical Laboratory Research and Development and Clinical Science Research... Crowne Plaza Clinical Research Program December 3, 2010 *VA Central Office Mental Hlth & Behav Sci-A...

  15. 75 FR 23847 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Science.gov (United States)

    2010-05-04

    ... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical... panels of the Joint Biomedical Laboratory Research and Development and Clinical Science Research and... & Behav Sci-A June 7, 2010 L'Enfant Plaza Hotel. Clinical Research Program June 9, 2010 *VA Central Office...

  16. 15 CFR 296.9 - Activities not permitted for joint ventures.

    Science.gov (United States)

    2010-01-01

    ... joint venture of any product, process, or service, other than the distribution among the parties to such venture, in accordance with such venture, of a product, process, or service produced by such venture, the... INNOVATION PROGRAM General § 296.9 Activities not permitted for joint ventures. The following activities are...

  17. The joint in psoriatic arthritis.

    Science.gov (United States)

    Mortezavi, Mahta; Thiele, Ralph; Ritchlin, Christopher

    2015-01-01

    Psoriatic arthritis (PsA), a chronic inflammatory joint disease associated with psoriasis, is notable for diversity in disease presentation, course and response to treatment. Equally varied are the types of musculoskeletal involvement which include peripheral and axial joint disease, dactylitis and enthesitis. In this review, we focus on the psoriatic joint and discuss pathways that underlie synovial, cartilage and bone inflammation and highlight key histopathologic features. The pivotal inflammatory mechanisms and pathobiology of PsA parallel findings in other forms of spondyloarthritis but are distinct from disease pathways described in rheumatoid synovitis and bone disease. The diagnosis of PsA from both a clinical and imaging perspective is also discussed.

  18. Jet joint undertaking annual report 1988

    International Nuclear Information System (INIS)

    1989-07-01

    The 1988 activity report of the Joint European Torus (JET) project, is presented. The report provides an overview of the scientific, technical and administrative status of the program. The background of the project, the description of JET and Euratom and International Fusion Programs are explained. The technical status of the machine is given and it includes: technical changes and achievements during 1988; details of the operational organisation of experiments and pulse statistics; and progress on enhancements in machine systems for future operations. The results of JET operations in 1988, under various conditions of heating and combined scenarios in different magnetic field configurations, are provided. The project budget situation, contractual arrangements, in 1988, and staff complements, are included

  19. Joint action aesthetics.

    Directory of Open Access Journals (Sweden)

    Staci Vicary

    Full Text Available Synchronized movement is a ubiquitous feature of dance and music performance. Much research into the evolutionary origins of these cultural practices has focused on why humans perform rather than watch or listen to dance and music. In this study, we show that movement synchrony among a group of performers predicts the aesthetic appreciation of live dance performances. We developed a choreography that continuously manipulated group synchronization using a defined movement vocabulary based on arm swinging, walking and running. The choreography was performed live to four audiences, as we continuously tracked the performers' movements, and the spectators' affective responses. We computed dynamic synchrony among performers using cross recurrence analysis of data from wrist accelerometers, and implicit measures of arousal from spectators' heart rates. Additionally, a subset of spectators provided continuous ratings of enjoyment and perceived synchrony using tablet computers. Granger causality analyses demonstrate predictive relationships between synchrony, enjoyment ratings and spectator arousal, if audiences form a collectively consistent positive or negative aesthetic evaluation. Controlling for the influence of overall movement acceleration and visual change, we show that dance communicates group coordination via coupled movement dynamics among a group of performers. Our findings are in line with an evolutionary function of dance-and perhaps all performing arts-in transmitting social signals between groups of people. Human movement is the common denominator of dance, music and theatre. Acknowledging the time-sensitive and immediate nature of the performer-spectator relationship, our study makes a significant step towards an aesthetics of joint actions in the performing arts.

  20. Joint action aesthetics

    Science.gov (United States)

    Vicary, Staci; Sperling, Matthias; von Zimmermann, Jorina; Richardson, Daniel C.

    2017-01-01

    Synchronized movement is a ubiquitous feature of dance and music performance. Much research into the evolutionary origins of these cultural practices has focused on why humans perform rather than watch or listen to dance and music. In this study, we show that movement synchrony among a group of performers predicts the aesthetic appreciation of live dance performances. We developed a choreography that continuously manipulated group synchronization using a defined movement vocabulary based on arm swinging, walking and running. The choreography was performed live to four audiences, as we continuously tracked the performers’ movements, and the spectators’ affective responses. We computed dynamic synchrony among performers using cross recurrence analysis of data from wrist accelerometers, and implicit measures of arousal from spectators’ heart rates. Additionally, a subset of spectators provided continuous ratings of enjoyment and perceived synchrony using tablet computers. Granger causality analyses demonstrate predictive relationships between synchrony, enjoyment ratings and spectator arousal, if audiences form a collectively consistent positive or negative aesthetic evaluation. Controlling for the influence of overall movement acceleration and visual change, we show that dance communicates group coordination via coupled movement dynamics among a group of performers. Our findings are in line with an evolutionary function of dance–and perhaps all performing arts–in transmitting social signals between groups of people. Human movement is the common denominator of dance, music and theatre. Acknowledging the time-sensitive and immediate nature of the performer-spectator relationship, our study makes a significant step towards an aesthetics of joint actions in the performing arts. PMID:28742849

  1. Telerehabilitation Feasibility in Total Joint Replacement

    Directory of Open Access Journals (Sweden)

    Mark J. Nelson

    2017-11-01

    Full Text Available Despite documented benefits, many Total Joint Replacement (TJR patients find it difficult to access rehabilitation following discharge from hospital. One solution to improve access for TJR patients is telerehabilitation. This study aimed to assess the feasibility of introducing a telerehabilitation program for TJR patients.   TJR patients at QEII Jubilee Hospital were invited to complete a questionnaire regarding their access, feelings towards and preferences in using technology. Seventy-five patients were recruited. Most patients had computer access (72% and internet (69% at home. Sixty-five percent of participants were willing to participate in telerehabilitation. A significant difference was found between older and younger patients. Watching videos on an electronic device was the preferred method for a technology-based home exercise program and phone call the preferred method of communication.  Results indicate telerehabilitation in the TJR population is feasible from the perspective of access to, feelings toward, and preferences for technology. Keywords: Hip replacement, Knee replacement, Telerehabilitation, Telemedicine, Total joint replacement

  2. Education: A Joint Transformation Enabler

    National Research Council Canada - National Science Library

    Alexander, Renita

    2003-01-01

    ... in an organization not known for its adaptability. Underlying the pursuit of transformational concepts necessary to respond to 21st century challenges is an emphasis on joint operations and doctrine...

  3. Finishing touch to joint venture

    CERN Multimedia

    2003-01-01

    "A new process for polishing titanium and its alloys has been announced following an agreement between Bripol (an Anopol/Delmet joint venture) of Birmingham and the European Organisation for Nuclear Reseach (CERN) in Geneva" (1 paragraph).

  4. MRI of the hip joint

    International Nuclear Information System (INIS)

    Czerny, C.; Noebauer-Huhmann, I.M.; Imhof, H.

    2005-01-01

    Magnetic resonance imaging (MRI) is performed to diagnose many pathologic conditions affecting the hip joint. Either conventional MRI (without contrast enhancement of the joint cavity) or MR arthrography is used to detect and most accurately differentiate hip joint pathologies. Conventional MRI is performed in cases of bone marrow edema, necrosis, arthrosis and especially the so-called ''activated arthrosis'', as well as in inflammatory and tumorous entities. MR arthography, which has only recently become available for use, is excellently suited for diagnosing lesions of the acetabular labrum, cartilage lesions, and free articular bodies. This article provides an overview about MRI characteristics and their accuracy of hip joint diseases and the impact on the therapeutic procedure. (orig.)

  5. Campus/Industry Joint Ventures.

    Science.gov (United States)

    McDonald, Eugene J.

    1985-01-01

    Opportunities for joint economic ventures of colleges and industry are discussed, and a variety of ventures undertaken by Duke University are outlined, including a health club, hotel, and office building. Tax and financing considerations are noted. (MSE)

  6. Engine mounts and structural joints

    Indian Academy of Sciences (India)

    mental studies are presented, and limitations of the passive device are briefly discussed. .... For the sake of simplifying formulations, several studies have used .... that the component mode synthesis methods work well when the joint stiffness is ...

  7. Practical aspects of joint implementation

    International Nuclear Information System (INIS)

    Michaelowa, A.

    1995-01-01

    Article 4, 2a of the UN Framework Convention on Climate Change states the possibility of joint policies of different countries to achieve national greenhouse gas reduction commitments (Joint Implementation). The cost of reducing greenhouse gas emissions can be reduced drastically if industrialized countries shift abatement activities to developing countries as marginal cost of reduction is much higher in the former countries. In this way economic efficiency of abatement measures can be raised to the point where marginal cost is equal all over the world. At the Conference of the Parties in Berlin in March 1995, criteria for Joint Implementation are to be established. The paper discusses possible forms of Joint Implementation and develops criteria

  8. Joint Logistics, Fact or Fiction?

    National Research Council Canada - National Science Library

    Carroll, Walton

    1998-01-01

    ...) and the evolution of Joint doctrine to meet these new demands. The focus of this examination remains at the strategic level and the ability of the Services to meet the logistical demands of the modern theater battlefield...

  9. Torsion testing of bed joints

    DEFF Research Database (Denmark)

    Hansen, Klavs Feilberg; Pedersen, Carsten Mørk

    2008-01-01

    This paper describes a simple test method for determining the torsion strength of a single bed joint between two bricks and presents results from testing using this test method. The setup for the torsion test is well defined, require minimal preparation of the test specimen and the test can...... be carried out directly in a normal testing machine. The torsion strength is believed to be the most important parameter in out-of-plane resistance of masonry walls subjected to bending about an axis perpendicular to the bed joints. The paper also contains a few test results from bending of small walls about...... an axis perpendicular to the bed joints, which indicate the close connection between these results and results from torsion tests. These characteristics make the torsion strength well suited to act as substitute parameter for the bending strength of masonry about an axis perpendicular to the bed joints....

  10. Management of Prosthetic Joint Infection.

    Science.gov (United States)

    Tande, Aaron J; Gomez-Urena, Eric O; Berbari, Elie F; Osmon, Douglas R

    2017-06-01

    Although uncommon, prosthetic joint infection is a devastating complication. This challenging condition requires a coordinated management approach to achieve good patient outcomes. This review details the general principles to consider when managing patients with prosthetic joint infection. The different medical/surgical treatment strategies and how to appropriately select a strategy are discussed. The data to support each strategy are presented, along with discussion of antimicrobial strategies in specific situations. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. Joint probabilities and quantum cognition

    International Nuclear Information System (INIS)

    Acacio de Barros, J.

    2012-01-01

    In this paper we discuss the existence of joint probability distributions for quantumlike response computations in the brain. We do so by focusing on a contextual neural-oscillator model shown to reproduce the main features of behavioral stimulus-response theory. We then exhibit a simple example of contextual random variables not having a joint probability distribution, and describe how such variables can be obtained from neural oscillators, but not from a quantum observable algebra.

  12. Joint probabilities and quantum cognition

    Energy Technology Data Exchange (ETDEWEB)

    Acacio de Barros, J. [Liberal Studies, 1600 Holloway Ave., San Francisco State University, San Francisco, CA 94132 (United States)

    2012-12-18

    In this paper we discuss the existence of joint probability distributions for quantumlike response computations in the brain. We do so by focusing on a contextual neural-oscillator model shown to reproduce the main features of behavioral stimulus-response theory. We then exhibit a simple example of contextual random variables not having a joint probability distribution, and describe how such variables can be obtained from neural oscillators, but not from a quantum observable algebra.

  13. Continuum description for jointed media

    International Nuclear Information System (INIS)

    Thomas, R.K.

    1982-04-01

    A general three-dimensional continuum description is presented for a material containing regularly spaced and approximately parallel jointing planes within a representative elementary volume. Constitutive relationships are introduced for linear behavior of the base material and nonlinear normal and shear behavior across jointing planes. Furthermore, a fracture permeability tensor is calculated so that deformation induced alterations to the in-situ values can be measured. Examples for several strain-controlled loading paths are presented

  14. Value of knee joint arthrography

    International Nuclear Information System (INIS)

    Luzsa, Gyoergy; Kiss Toth, Peter

    1985-01-01

    On the basis of the literature and the analysis of 204 examinations, the method and clinical application of knee joint arthrography are reviewed. 50 out of the 54 operated cases were perfectly diagnosed. The double contrast knee joint arthrography can be applied to detect meniscus changes, popliteal cysts, synovial disorders and chondral defects. The effectiveness of arthrography and arthroscopy was compared and the introduction of the former in each county seat is suggested. (author)

  15. F-Gas Partnership Programs

    Science.gov (United States)

    Provides basic information and resources for the Fluorinated Gas Partnership Programs, which were launched as a joint effort by EPA and industry groups to reduce the amount of fluorinated gases emitted through a variety of industrial processes.

  16. Fiscal 1999 report on basic research for promotion of joint implementation programs. Research on collection and utilization of coal mine methane gas in Russia (Kuznetsk coal field); Russia (Kuznetsk tanden) ni okeru tanko methane gas kaishu riyo chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    The above-mentioned effort is to comply with the COP3 (Third Session of the Conference of the Parties to the United Nations Framework Convention on Climate Change) joint implementation clause. At this coal field, mining facilities are growing superannuated and obsolescent in the prolonged business depression, causing frequent occurrence of disasters such as gas explosions. The coal mine gas collection rate at the Kuznetsk coal field is as low as 17%, with concern for safety discouraging sufficient collection. Even the small amount of the collected gas is, in the absence of gas utilizing facilities, totally discharged into the air. For the mitigation of global warming, for mining safety, and for the establishment of a foundation for business, it is desired that coal mine methane gas collection/utilization facilities and related technologies be introduced into the coal field. Gas purging from the pits is incomplete, which is attributed to the lack of equipment capable of excavating proper-diameter bores longer than 100m for longwall mining. Ventilation also needs improvement. The research is under way on the premise that highly reliable intermediate range (300m) boring equipment and gas management technologies will be available. Collection of gas of a 30-35% concentration level at a collection rate of 40% is the target. (NEDO)

  17. Proceedings from the second science team meeting of the United States of America Department of Energy and the People's Republic of China Academia Sinica Joint Research Program on CO/sub 2/-Induced Climate Change

    Energy Technology Data Exchange (ETDEWEB)

    1988-06-01

    The six papers presented here as the proceedings of this second Joint CO/sub 2/ Research Team Meeting are examples of the research progress during the last two years. The first paper is documentation of the first numerical climate simulation model developed by the Institute of Atmospheric Physics in Beijing. Two papers from the National Oceanic and Atmospheric Administration's National Climatic Data Center at Asheville, North Carolina, demonstrate the work being done on the United States Historical Climatology Network data (the time series of temperature, precipitation, and sunshine) in the US. The fourth paper speaks of climate variability on a regional scale being much larger than that based on averages of global-wide data and therefore more difficult to predict. The China Precipitation Proxy Index covers a period of 510 years. This permits comparison of contemporary climate patterns (i.e., the last 100 years) with the period of the Little Ice Age when the mean temperature over China was 2/degree/ colder than present. The fifth paper is fascinating documentation of the effects of climate change upon the wild elephants whose habitat has shifted from as far north as Beijing, in historical times, to a currently small, sequestered section in the southwest corner of the country. The final paper demonstrates the pragmatic exchange of both data and technical assistance between the two countries.

  18. Fiscal 1999 report on basic research for promotion of joint implementation programs. Basic research on modification of Symferopoloskaya thermoelectric power station; 1999 nendo Symferopoloskaya karyoku hatsudensho kaishu kiso chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This effort complies with the COP3 (Third Session of the Conference of the Parties to the United Nations Framework Convention on Climate Change) joint implementation clause. The plan is to replace the existing old facilities with three units of 107MW rated single shaft combined cycle power plants. Each unit comprises one 70MW rated gas turbine generator, one water circulating reheat type steam turbine/air cooled synchronous generator, and one exhaust heat recovery boiler. The rated output will be 321MW in total, and the maximum heat supply 71Gcal/hour. Fuel consumption will be less by 304,800 tons/year in terms of oil at a reduction rate of 46.3%. Greenhouse gas will be less by 712,089 tons/year in terms of CO2 at a reduction rate of 46.3%. The modification will cost 224-million US dollars. To secure profitability under the project and to keep EIRR (economic internal rate return) at 15% or higher, CO2 has to sell at 13 US dollars/ton in terms of CO2 or a US dollar has to be equivalent to or less than 4.9 UAHs (with repayment to be made in US dollars). Profitability will vary extensively, dependent on fluctuations in the exchange rate reflecting the Ukrainian economic state and on the magnitude of greenhouse gas trading scheme. (NEDO)

  19. Fiscal 1999 research report. Basic research for promotion of joint implementation programs (Energy efficiency survey at Noboil Refinery of Ufa City); 1999 nendo Ufa shi Noboil seiyusho ni kansuru sho energy chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    The aim is to explore projects that will lead to joint implementations for greenhouse gas emission reduction, and a survey was conducted at the Bashneftechim Refineries, Ufa City, Bashkir Republic, Russian Federation. A feasibility study was carried out involving energy efficiency improvement for oil refining related units such as atmospheric and vacuum distillators. In the energy efficiency survey, studies covered energy efficiency improvement in the existing equipment through the modification of the normal and vacuum distillators, visbreaker, vacuum desulfurizer for light oil, and the process heating furnace of the catalytic cracking equipment, for a reduction in fuel consumption by realizing combustion excess air ratio control; the installation of an air preheater or a waste heater boiler for the collection of heat from combustion exhaust gas; the addition of heat exchangers and the optimization of their arrangement for an increase in the amount of heat recoverable from hot oil; the replacement of obsolete instruments and controllers with state-of-the-art types for higher energy efficiency in the control of distillation tower operation, etc. It is desired that this energy saving project will be embodied for a reduction in CO2 emissions. (NEDO)

  20. JAERI RERTR program

    International Nuclear Information System (INIS)

    Sato, M.

    1983-01-01

    In 1979, Japan Atomic Energy Research Institute (JAERI) has started a five year program for the utilization of reduced enrichment uranium fuel, in place of currently used highly enriched uranium fuel for the JAERI Research and Test Reactors (RERTR), such as the JRR-2 (10 MWt), the JRR-4 35 MWt), the JMTR(50 MWO and the JMTRC (100 Wt, nuclear mockup of the JMTR), for contributing to the reduction of proliferation concerns. In order to assess the feasibility of converting the JAERI reactors to use of fuel with reduced enrichment uranium, ANL and JAERI have embarked on a joint study program since January 1980. This document provides outlines of the JAERI RERTR Program and of the ANL-JAERI Joint Study, and main results of JAERI's Phase A report which was made under the joint study

  1. Optimization of contrast of MR images in imaging of knee joint

    International Nuclear Information System (INIS)

    Szyblinski, K.; Bacic, G.

    1994-01-01

    The work describes the method of contrast optimization in magnetic resonance imaging. Computer program presented in the report allows analysis of contrast in selected tissues as a function of experiment parameters. Application to imaging of knee joint is presented

  2. Joint Stars and the Darkstar Unmanned Aerial Vehicle: An Operating and Support Cost Estimate

    National Research Council Canada - National Science Library

    SIKRA, JAMES

    1998-01-01

    With the 1997 Quadrennial Defense Review's (QDR) reduction of Joint STARS aircraft from 19 to 13, the program will not be able to maintain the Department of Defense requirement to fully support two major theater wars (MTWs...

  3. Strategic Change and the Joint Terrorism Task Force: Ideas and Recommendations

    National Research Council Canada - National Science Library

    D'Angelo, Anthony P

    2007-01-01

    ... and the multidisciplinary Joint Terrorism Task Forces. The terrorist attacks served as a catalyst for evaluating cultural, psychological and organizational processes, policies and procedures that influenced the FBI and impacted the JTTF program...

  4. Flat H Redundant Frangible Joint Development

    Science.gov (United States)

    Brown, Chris

    2016-01-01

    Orion and Commercial Crew Program (CCP) Partners have chosen to use frangible joints for certain separation events. The joints currently available are zero failure tolerant and will be used in mission safety applications. The goal is to further develop a NASA designed redundant frangible joint that will lower flight risk and increase reliability. FY16 testing revealed a successful design in subscale straight test specimens that gained efficiency and supports Orion load requirements. Approach / Innovation A design constraint is that the redundant joint must fit within the current Orion architecture, without the need for additional vehicle modification. This limitation required a design that changed the orientation of the expanding tube assemblies (XTAs), by rotating them 90deg from the standard joint configuration. The change is not trivial and affects the fracture mechanism and structural load paths. To address these changes, the design incorporates cantilevered arms on the break plate. The shock transmission and expansion of the XTA applies force to these arms and creates a prying motion to push the plate walls outward to the point of structural failure at the notched section. The 2014 test design revealed that parts could slip during functioning wasting valuable energy needed to separate the structure with only a single XTA functioning. Dual XTA functioning fully separated the assembly showing a discrepancy can be backed up with redundancy. Work on other fully redundant systems outside NASA is limited to a few patents that have not been subjected to functionality testing Design changes to prevent unwanted slippage (with ICA funding in 2015) showed success with a single XTA. The main goal for FY 2016 was to send the new Flat H RFJ to WSTF where single XTA test failures occurred back in 2014. The plan was to gain efficiency in this design by separating the Flat H RFJ with thicker ligaments with dimensions baselined in 2014. Other modifications included geometry

  5. Building Capacity for Complementary and Integrative Medicine Through a Large, Cross-Agency, Acupuncture Training Program: Lessons Learned from a Military Health System and Veterans Health Administration Joint Initiative Project.

    Science.gov (United States)

    Niemtzow, Richard; Baxter, John; Gallagher, Rollin M; Pock, Arnyce; Calabria, Kathryn; Drake, David; Galloway, Kevin; Walter, Joan; Petri, Richard; Piazza, Thomas; Burns, Stephen; Hofmann, Lew; Biery, John; Buckenmaier, Chester

    2018-03-26

    Complementary and integrative medicine (CIM) use in the USA continues to expand, including within the Military Health System (MHS) and Veterans Health Administration (VHA). To mitigate the opioid crisis and provide additional non-pharmacological pain management options, a large cross-agency collaborative project sought to develop and implement a systems-wide curriculum, entitled Acupuncture Training Across Clinical Settings (ATACS). ATACS curriculum content and structure were created and refined over the course of the project in response to consultations with Subject Matter Experts and provider feedback. Course content was developed to be applicable to the MHS and VHA environments and training was open to many types of providers. Training included a 4-hr didactic and "hands on" clinical training program focused on a single auricular acupuncture protocol, Battlefield Acupuncture. Trainee learning and skills proficiency were evaluated by trainer-observation and written examination. Immediately following training, providers completed an evaluation survey on their ATACS experience. One month later, they were asked to complete another survey regarding their auricular acupuncture use and barriers to use. The present evaluation describes the ATACS curriculum, faculty and trainee characteristics, as well as trainee and program developer perspectives. Over the course of a 19-mo period, 2,712 providers completed the in-person, 4-hr didactic and hands-on clinical training session. Due to the increasing requests for training, additional ATACS faculty were trained. Overall, 113 providers were approved to be training faculty. Responses from the trainee surveys indicated high satisfaction with the ATACS training program and illuminated several challenges to using auricular acupuncture with patients. The most common reported barrier to using auricular acupuncture was the lack of obtaining privileges to administer auricular acupuncture within clinical practice. The ATACS program

  6. Japan-U.S. Joint Ventures in Higher Education: Language Education in an Uncertain Future.

    Science.gov (United States)

    Clayton, Thomas

    1991-01-01

    Examines Japanese-U.S. joint venture language or U.S.-style education programs in Japan. These programs offer language and cultural education classes for those interested in English and for students who have failed in the Japanese education system. Problems facing these programs and the need to explore new, English-language education markets are…

  7. Structural optimization of an alternate design for the Space Shuttle solid rocket booster field joint

    Science.gov (United States)

    Barthelemy, Jean-Francois M.; Rogers, James L., Jr.; Chang, Kwan J.

    1987-01-01

    A structural optimization procedure is used to determine the shape of an alternate design for the Shuttle's solid rocket booster field joint. In contrast to the tang and clevis design of the existing joint, this alternate design consists of two flanges bolted together. Configurations with 150 studs of 1 1/8 in diameter and 135 studs of 1 3/16 in diameter are considered. Using a nonlinear programming procedure, the joint weight is minimized under constraints on either von Mises or maximum normal stresses, joint opening and geometry. The procedure solves the design problem by replacing it by a sequence of approximate (convex) subproblems; the pattern of contact between the joint halves is determined every few cycles by a nonlinear displacement analysis. The minimum weight design has 135 studs of 1 3/16 in diameter and is designed under constraints on normal stresses. It weighs 1144 lb per joint more than the current tang and clevis design.

  8. The tensile strength of mechanical joint prototype of lontar fiber composite

    Science.gov (United States)

    Bale, Jefri; Adoe, Dominggus G. H.; Boimau, Kristomus; Sakera, Thomas

    2018-03-01

    In the present study, an experimental activity has been programmed to investigate the effect of joint prototype configuration on tensile strength of lontar (Borassus Flabellifer) fiber composite. To do so, a series of tests were conducted to establish the tensile strength of different joint prototype configuration specimen of lontar fiber composite. In addition, post observation of macroscope was used to map damage behavior. The analysis of lontar fiber composite is a challenge since the material has limited information than others natural fiber composites materials. The results shown that, under static tensile loading, the tensile strength of 13 MPa produced by single lap joint of lontar fiber composite is highest compare to 11 MPa of tensile strength generated by step lap joint and double lap joint where produced the lowest tensile strength of 6 MPa. It is concluded that the differences of tensile strength depend on the geometric dimensions of the cross-sectional area and stress distribution of each joint prototype configuration.

  9. Branching miter joints : principles and artwork

    NARCIS (Netherlands)

    Verhoeff, T.; Verhoeff, K.; Hart, G.W.; Sarhangi, R.

    2010-01-01

    A miter joint connects two beams, typically of the same cross section, at an angle such that the longitudinal beam edges continue across the joint. When more than two beams meet in one point, like in a tree, we call this a branching joint. In a branching miter joint, the beams’ longitudinal edges

  10. 12 CFR 347.107 - Joint ventures.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Joint ventures. 347.107 Section 347.107 Banks... INTERNATIONAL BANKING § 347.107 Joint ventures. (a) Joint ventures. If a bank, directly or indirectly, acquires or holds an equity interest in a foreign organization that is a joint venture, and the bank or its...

  11. About the Joint Chiefs of Staff

    Science.gov (United States)

    Skip to main content (Press Enter). Toggle navigation Joint Chiefs of Staff Joint Chiefs of Staff Joint Chiefs of Staff Facebook Twitter YouTube Flickr Blog Instagram Search JCS: Search Search Search JCS: Search Home Media News Photos Videos Publications About The Joint Staff Chairman Vice Chairman

  12. US/USSR cooperative program in open-cycle MHD electrical power gneration. Joint test report No. 2: tests in the U-25B facility; MHD generator test No. 3

    International Nuclear Information System (INIS)

    Tempelmeyer, K.E.; Sokolov, Y.N.

    1979-04-01

    The third joint test with a Soviet U-25B MHD generator and a US superconducting magnet system (SCMS) was conducted in the Soviet U-25B Facility. The primary objectives of the 3rd test were: (1) to operate the facility and MHD channel over a wider range of test parameters, and (2) to study the performance of all components and systems of the flow train at increased mass flow rates of combustion products (up to 4 kg/s), at high magnetic-field induction (up to 5 T), and high values of the electrical field in the MHD generator. The third test has demonstrated that all components and systems of the U-25B facility performed reliably. The electric power generated by the MHD generaor reached a maximum of 575 kW during this test. The MHD generator was operated under electrical loading conditions for 9 hours, and the combustor for a total of approximately 14 hours. Very high Hall fields (2.1 kV/m) were produced in the MHD channel, with a total Hall voltage of 4.24 kV. A detailed description is given of (1) performance of all components and systems of the U-25B facility, (2) analysis of the thermal, gasdynamic, and electrical characteristics of the MHD generator, (3) results of plasma diagnostic studies, (4) studies of vibrational characteristics of the flow train, (5) fluctuation of electrodynamic and gasdynamic parameters, (6) interaction of the MHD generator with the superconducting magnet, and (7) an operational problem, which terminated the test

  13. What Is the Tech Prep/Associate Degree Program?

    Science.gov (United States)

    Parnell, Dale

    1993-01-01

    Discusses the nature, importance, and future of the Tech Prep/Associate Degree program. Suggests that these programs must move beyond simple articulation and become aggressive in jointly examining, developing, and sustaining high quality educational programs. (JOW)

  14. Fiscal 1997 survey report on the jointly executed/promoted basic survey project (the jointly executed activity Japan Program). Feasibility survey for CO2 reduction by deregulating heavy traffic at specified crossings in Bangkok, Thailand; 1997 nendo chosa hokokusho (kyodo jisshi suishin kiso chosa jigyo (kyodo jisshi katsudo Japan program)). Taikoku Bangkok no tokutei kosaten ni okeru kotsu jutai kanwa ni yoru CO2 sakugen kanosei chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The monetary crisis in Thailand with the baht drop in July 1997 as a beginning rapidly worsened the Thai economy. With it, the number of automobiles sold sharply declined, and automobile manufacturers were also heavily damaged as seen in the temporary discontinued production, etc. Under such economic situation, a discussion was made on execution of the project with the Thai Automotive Industry Association (TAIA), a partner at the Thai side. As a result, agreement was made on the positioning of the project, role sharing, and selection of measures against heavy traffic as follows: Japan Automobile Manufacturers Association (JAMA) conducts a feasibility study, proposal of a construction plan and confirmation of effects, and bears the costs. TAIA bears the execution and cost of construction (Due to the worsened Thai economy, JAMA paid almost all the construction expenses). In the light of the economic situation in Thailand, `improvement of the signal control system` was selected as an execution candidate, which has the highest cost effect among the measures against heavy traffic. In the future, the application, registration and execution are done for joint activities for the project. 49 figs., 59 tabs.

  15. Degenerative Joint Diseases and Neuroinflammation.

    Science.gov (United States)

    Fusco, Mariella; Skaper, Stephen D; Coaccioli, Stefano; Varrassi, Giustino; Paladini, Antonella

    2017-04-01

    Rheumatic and joint diseases, as exemplified by osteoarthritis and rheumatoid arthritis, are among the most widespread painful and disabling pathologies across the globe. Given the continuing rise in life expectancy, their prevalence is destined to grow. Osteoarthritis, a degenerative joint disease, is, in particular, on its way to becoming the fourth leading cause of disability worldwide by 2020, with the rising incidence of obesity in addition to age being important factors. It is estimated that 25% of osteoarthritic individuals are unable to perform daily activities. Accompanying osteoarthritis is rheumatoid arthritis, which is a chronic systemic disease that often causes pain and deformity. At least 50% of those affected are unable to remain gainfully employed within 10 years of disease onset. A growing body of evidence now points to inflammation, locally and more systemically, as a promoter of damage to joints and bones, as well as joint-related functional deficits. The pathogenesis underlying joint diseases remains unclear; however, it is currently believed that cross-talk between cartilage and subchondral bone-and loss of balance between these two structures in joint diseases-is a critical element. This view is amplified by the presence of mast cells, whose dysregulation is associated with alterations of junction structures (cartilage, bone, synovia, matrix, nerve endings, and blood vessels). In addition, persistent activation of mast cells facilitates the development of spinal neuroinflammation mediated through their interaction with microglia. Unfortunately, current treatment strategies for rheumatic and articular disease are symptomatic and do little to limit disease progression. Research now should be directed at therapeutic modalities that target osteoarticular structural elements and thereby delaying disease progression and joint replacement. © 2016 World Institute of Pain.

  16. Management of acromioclavicular joint injuries.

    Science.gov (United States)

    Li, Xinning; Ma, Richard; Bedi, Asheesh; Dines, David M; Altchek, David W; Dines, Joshua S

    2014-01-01

    Acromioclavicular joint injuries are among the most common shoulder girdle injuries in athletes and most commonly result from a direct force to the acromion with the arm in an adducted position. Acromioclavicular joint injuries often present with associated injuries to the glenohumeral joint, including an increased incidence of superior labrum anterior posterior (SLAP) tears that may warrant further evaluation and treatment. Anteroposterior stability of the acromioclavicular joint is conferred by the capsule and acromioclavicular ligaments, of which the posterior and superior ligaments are the strongest. Superior-inferior stability is maintained by the coracoclavicular (conoid and trapezoid) ligaments. Type-I or type-II acromioclavicular joint injuries have been treated with sling immobilization, early shoulder motion, and physical therapy, with favorable outcomes. Return to activity can occur when normal shoulder motion and strength are obtained and the shoulder is asymptomatic as compared with the contralateral normal extremity. The management of type-III injuries remains controversial and is individualized. While a return to the previous level of functional activity with nonsurgical treatment has been documented in a number of case series, surgical reduction and coracoclavicular ligament reconstruction has been associated with a favorable outcome and can be considered in patients who place high functional demands on their shoulders or in athletes who participate in overhead sports. Surgical management is indicated for high-grade (≥type IV) acromioclavicular joint injuries to achieve anatomic reduction of the acromioclavicular joint, reconstruction of the coracoclavicular ligaments, and repair of the deltotrapezial fascia. Outcomes after surgical reconstruction of the coracoclavicular ligaments have been satisfactory with regard to achieving pain relief and return to functional activities, but further improvements in the biomechanical strength of these

  17. Environmental Technology Verification: Baghouse Filtration Products--TDC Filter Manufacturing, Inc., SB025 Filtration Media

    Science.gov (United States)

    The U.S. Environmental Protection Agency (EPA) has created the Environmental Technology Verification (ETV) Program to facilitate the deployment of innovative or improved environmental technologies through performance verification and dissemination of information. ETV seeks to ach...

  18. GENERIC VERIFICATION PROTOCOL FOR DETERMINATION OF EMISSIONS REDUCTIONS FROM SELECTIVE CATALYTIC REDUCTIONS CONTROL TECHNOLOGIES FOR HIGHWAY, NONROAD, AND STATIONARY USE DIESEL ENGINES

    Science.gov (United States)

    The protocol describes the Environmental Technology Verification (ETV) Program's considerations and requirements for verification of emissions reduction provided by selective catalytic reduction (SCR) technologies. The basis of the ETV will be comparison of the emissions and perf...

  19. ENVIRONMENTAL TECHNOLOGY VERIFICATION--TEST REPORT OF MOBILE SOURCE EMISSION CONTROL DEVICES, FLINT HILLS RESOURCES, LP, CCD15010 DIESEL FUEL FORMULATION WITH HITEC4121 ADDITIVE

    Science.gov (United States)

    The U.S. Environmental Protection Agency (EPA) has created the Environmental Technology Verification (ETV) Program to facilitate the deployment of innovative or improved environmental technologies through performance verification and dissemination of information. ETV seeks to ach...

  20. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT: MOBILE SOURCE RETROFIT AIR POLLUTION CONTROL DEVICES: CLEAN CLEAR FUEL TECHNOLOGIES, INC.’S, UNIVERSAL FUEL CELL

    Science.gov (United States)

    The U.S. EPA's Office of Research and Development operates the Environmental Technology Verification (ETV) program to facilitate the deployment of innovative technologies through performance verification and information dissemination. Congress funds ETV in response to the belief ...