WorldWideScience

Sample records for program design principles

  1. Database principles programming performance

    CERN Document Server

    O'Neil, Patrick

    2014-01-01

    Database: Principles Programming Performance provides an introduction to the fundamental principles of database systems. This book focuses on database programming and the relationships between principles, programming, and performance.Organized into 10 chapters, this book begins with an overview of database design principles and presents a comprehensive introduction to the concepts used by a DBA. This text then provides grounding in many abstract concepts of the relational model. Other chapters introduce SQL, describing its capabilities and covering the statements and functions of the programmi

  2. Algorithmic Principles of Mathematical Programming

    NARCIS (Netherlands)

    Faigle, Ulrich; Kern, Walter; Still, Georg

    2002-01-01

    Algorithmic Principles of Mathematical Programming investigates the mathematical structures and principles underlying the design of efficient algorithms for optimization problems. Recent advances in algorithmic theory have shown that the traditionally separate areas of discrete optimization, linear

  3. Optimal Input Design for Aircraft Parameter Estimation using Dynamic Programming Principles

    Science.gov (United States)

    Morelli, Eugene A.; Klein, Vladislav

    1990-01-01

    A new technique was developed for designing optimal flight test inputs for aircraft parameter estimation experiments. The principles of dynamic programming were used for the design in the time domain. This approach made it possible to include realistic practical constraints on the input and output variables. A description of the new approach is presented, followed by an example for a multiple input linear model describing the lateral dynamics of a fighter aircraft. The optimal input designs produced by the new technique demonstrated improved quality and expanded capability relative to the conventional multiple input design method.

  4. RFID design principles

    CERN Document Server

    Lehpamer, Harvey

    2012-01-01

    This revised edition of the Artech House bestseller, RFID Design Principles, serves as an up-to-date and comprehensive introduction to the subject. The second edition features numerous updates and brand new and expanded material on emerging topics such as the medical applications of RFID and new ethical challenges in the field. This practical book offers you a detailed understanding of RFID design essentials, key applications, and important management issues. The book explores the role of RFID technology in supply chain management, intelligent building design, transportation systems, military

  5. Using Principles of Programmed Instruction

    Science.gov (United States)

    Huffman, Harry

    1971-01-01

    Although programmed instruction in accounting is available, it is limited in scope and in acceptance. Teachers, however, may apply principles of programming to the individualizing of instruction. (Author)

  6. Designing an Effective Prevention Program: Principles Underlying the Rand Smoking and Drug Prevention Experiment.

    Science.gov (United States)

    Ellickson, Phyllis L.

    This paper describes the Project ALERT program (Adolescent Learning Experiences in Resistance Training) which was established by the Rand Corporation to prevent smoking and drug use among seventh graders. The program is based on the social influence model of drug use initiation. Curriculum features are described including motivation to resist and…

  7. Principles of Protocol Design

    DEFF Research Database (Denmark)

    Sharp, Robin

    This is a new and updated edition of a book first published in 1994. The book introduces the reader to the principles used in the construction of a large range of modern data communication protocols, as used in distributed computer systems of all kinds. The approach taken is rather a formal one...

  8. Principles and Criteria for Design

    DEFF Research Database (Denmark)

    Beghin, D.; Cervetto, D.; Hansen, Peter Friis

    1997-01-01

    The mandate of ISSC Committee IV.1 on principles and Criteria for Design is to report on the following:The ongoing concern for quantification of general economic and safety criteria for marine structures and for the development of appropriate principles for rational life cycle design using...

  9. Update heat exchanger designing principles

    International Nuclear Information System (INIS)

    Lipets, A.U.; Yampol'skij, A.E.

    1985-01-01

    Update heat exchanger design principles are analysed. Different coolant pattern in a heat exchanger are considered. It is suggested to rationally organize flow rates irregularity in it. Applying on heat exchanger designing measures on using really existing temperature and flow rate irregularities will permit to improve heat exchanger efficiency. It is expedient in some cases to artificially produce irregularities. In this connection some heat exchanger design principles must be reviewed now

  10. Cavity design programs

    International Nuclear Information System (INIS)

    Nelson, E.M.

    1996-01-01

    Numerous computer programs are available to help accelerator physicists and engineers model and design accelerator cavities and other microwave components. This article discusses the problems these programs solve and the principles upon which these programs are based. Some examples of how these programs are used in the design of accelerator cavities are also given

  11. Logical database design principles

    CERN Document Server

    Garmany, John; Clark, Terry

    2005-01-01

    INTRODUCTION TO LOGICAL DATABASE DESIGNUnderstanding a Database Database Architectures Relational Databases Creating the Database System Development Life Cycle (SDLC)Systems Planning: Assessment and Feasibility System Analysis: RequirementsSystem Analysis: Requirements Checklist Models Tracking and Schedules Design Modeling Functional Decomposition DiagramData Flow Diagrams Data Dictionary Logical Structures and Decision Trees System Design: LogicalSYSTEM DESIGN AND IMPLEMENTATION The ER ApproachEntities and Entity Types Attribute Domains AttributesSet-Valued AttributesWeak Entities Constraint

  12. Optimal decisions principles of programming

    CERN Document Server

    Lange, Oskar

    1971-01-01

    Optimal Decisions: Principles of Programming deals with all important problems related to programming.This book provides a general interpretation of the theory of programming based on the application of the Lagrange multipliers, followed by a presentation of the marginal and linear programming as special cases of this general theory. The praxeological interpretation of the method of Lagrange multipliers is also discussed.This text covers the Koopmans' model of transportation, geometric interpretation of the programming problem, and nature of activity analysis. The solution of t

  13. Dynamic Programming Foundations and Principles

    CERN Document Server

    Sniedovich, Moshe

    2010-01-01

    Focusing on the modeling and solution of deterministic multistage decision problems, this book looks at dynamic programming as a problem-solving optimization method. With over 400 useful references, this edition discusses the dynamic programming analysis of a problem, illustrates the rationale behind this analysis, and clarifies the theoretical grounds that justify the rationale. It also explains the meaning and role of the concept of state in dynamic programming, examines the purpose and function of the principle of optimality, and outlines solution strategies for problems defiant of conventi

  14. Design Principles for Hybrid Ventilation

    DEFF Research Database (Denmark)

    Heiselberg, Per

    For many years mechanical and natural ventilation systems have developed separately. Naturally, the next step in this development is the development of ventilation concepts that utilize and combine the best features from each system to create a new type of ventilation system -Hybrid Ventilation. ....... The hybrid ventilation concepts, design challenges and - principles are discussed and illustrated by four building examples....

  15. Structuring Principles for the Designer

    DEFF Research Database (Denmark)

    Miller, Thomas Dedenroth; Pedersen, Per Erik Elgård

    1998-01-01

    This paper suggests a list of structuring principles that support the designer in making alternative concepts for product architectures. Different architectures may support different points of diversification in the product life-cycle. The aim is to balance reuse of resources and reduction...

  16. Fundamental Principles of Alarm Design

    DEFF Research Database (Denmark)

    Us, Tolga; Jensen, Niels; Lind, Morten

    2011-01-01

    Traditionally alarms are designed on the basis of empirical guidelines rather than on a sound scientific framework rooted in a theoretical foundation for process and control system design. This paper proposes scientific principles and a methodology for design of alarms based on a functional...... be applied to any engineering system which can be modeled by MFM. The methodology provides a set of alarms which can facilitate event interpretation and operator support for abnormal situation management. The proposed design methodology provides the information content of the alarms, but does not deal...

  17. Principles of modern digital design

    CERN Document Server

    Lala, Parag K

    2007-01-01

    A major objective of this book is to fill the gap between traditional logic design principles and logic design/optimization techniques used in practice. Over the last two decades several techniques for computer-aided design and optimization of logic circuits have been developed. However, underlying theories of these techniques are inadequately covered or not covered at all in undergraduate text books. This book covers not only the ""classical"" material found in current text books but also selected materials that modern logic designers need to be familiar with.

  18. Industrial instrumentation principles and design

    CERN Document Server

    Padmanabhan, Tattamangalam R

    2000-01-01

    Pneumatic, hydraulic and allied instrumentation schemes have given way to electronic schemes in recent years thanks to the rapid strides in electronics and allied areas. Principles, design and applications of such state-of-the-art instrumentation schemes form the subject matter of this book. Through representative examples, the basic building blocks of instrumentation schemes are identified and each of these building blocks discussed in terms of its design and interface characteristics. The common generic schemes synthesized with such building blocks are dealt with subsequently. This forms the scope of Part I. The focus in Part II is on application. Displacement and allied instrumentation, force and allied instrumentation and process instrumentation in terms of temperature, flow, pressure level and other common process variables are dealt with separately and exhaustively. Despite the diversity in the sensor principles and characteristics and the variety in the applications and their environments, it is possib...

  19. Communications receivers principles and design

    CERN Document Server

    Rohde, Ulrich L; Zahnd, Hans

    2017-01-01

    This thoroughly updated guide offers comprehensive explanations of the science behind today’s radio receivers along with practical guidance on designing, constructing, and maintaining real-world communications systems. You will explore system planning, antennas and antenna coupling, amplifiers and gain control, filters, mixers, demodulation, digital communication, and the latest software defined radio (SDR) technology. Written by a team of telecommunication experts, Communications Receivers: Principles and Design, Fourth Edition, features technical illustrations, schematic diagrams, and detailed examples. Coverage includes: • Basic radio considerations • Radio receiver characteristics • Receiver system planning • Receiver implementation considerations • RF and baseband techniques for Software-Defined Radios • Transceiver SDR considerations • Antennas and antenna coupling • Mixers • Frequency sources and control • Ancillary receiver circuits • Performance measurement

  20. Design principles for precision mechanisms

    CERN Document Server

    Soemers, Herman

    2011-01-01

    The successful design of mechanisms for products, tools and equipment relies on excellent concepts and properly designed details. Both are covered in this book. Many of the examples presented have been realised in practice and properly evaluated, giving the reader/designer a high level of confidence. Every example comes with the considerations underlying the application and the limitations of the particular idea. This book is based on the work started in the 1960s by W. van der Hoek at Philips in Eindhoven, the Netherlands, and subsequently continued by M.P. Koster, culminating in the Dutch-language book “Constructieprincipes” [Design principles for accurate movement and positioning]. The core of their design approach has been preserved, while theory and examples were updated and the English language was adopted to reach a broad audience within the Netherlands as well as abroad. Herman (H.M.J.R.) Soemers is associated with the University of Twente, Enschede, the Netherlands. He also works as a technolog...

  1. Visual Design Principles: An Empirical Study of Design Lore

    Science.gov (United States)

    Kimball, Miles A.

    2013-01-01

    Many books, designers, and design educators talk about visual design principles such as balance, contrast, and alignment, but with little consistency. This study uses empirical methods to explore the lore surrounding design principles. The study took the form of two stages: a quantitative literature review to determine what design principles are…

  2. Design principles for riboswitch function.

    Directory of Open Access Journals (Sweden)

    Chase L Beisel

    2009-04-01

    Full Text Available Scientific and technological advances that enable the tuning of integrated regulatory components to match network and system requirements are critical to reliably control the function of biological systems. RNA provides a promising building block for the construction of tunable regulatory components based on its rich regulatory capacity and our current understanding of the sequence-function relationship. One prominent example of RNA-based regulatory components is riboswitches, genetic elements that mediate ligand control of gene expression through diverse regulatory mechanisms. While characterization of natural and synthetic riboswitches has revealed that riboswitch function can be modulated through sequence alteration, no quantitative frameworks exist to investigate or guide riboswitch tuning. Here, we combined mathematical modeling and experimental approaches to investigate the relationship between riboswitch function and performance. Model results demonstrated that the competition between reversible and irreversible rate constants dictates performance for different regulatory mechanisms. We also found that practical system restrictions, such as an upper limit on ligand concentration, can significantly alter the requirements for riboswitch performance, necessitating alternative tuning strategies. Previous experimental data for natural and synthetic riboswitches as well as experiments conducted in this work support model predictions. From our results, we developed a set of general design principles for synthetic riboswitches. Our results also provide a foundation from which to investigate how natural riboswitches are tuned to meet systems-level regulatory demands.

  3. Principles of a reversible programming language

    DEFF Research Database (Denmark)

    Yokoyama, Tetsuo; Axelsen, Holger Bock; Glück, Robert

    2008-01-01

    The principles of reversible programming languages are explicated and illustrated with reference to the design of a high-level imperative language, Janus. The fundamental properties for such languages include backward as well as forward determinism and reversible updates of data. The unique design...... languages, and demonstrate this for Janus. We show the practicality of the language by implementation of a reversible fast Fourier transform. Our results indicate that the reversible programming paradigm has fundamental properties that are relevant to many different areas of computer science....... features of the language include explicit post-condition assertions, direct access to an inverse semantics and the possibility of clean (i.e., garbage-free) computation of injective functions. We suggest the clean simulation of reversible Turing machines as a criterion for computing strength of reversible...

  4. The promise and challenge of practice-research collaborations: Guiding principles and strategies for initiating, designing, and implementing program evaluation research.

    Science.gov (United States)

    Secret, Mary; Abell, Melissa L; Berlin, Trey

    2011-01-01

    The authors present a set of guiding principles and strategies to facilitate the collaborative efforts of social work researchers and practitioners as they initiate, design, and implement outcome evaluations of human service interventions and programs. Beginning with an exploration of the interpersonal barriers to practice-research collaborations, and building on their experiences in successfully completing a community-based research evaluation, the authors identify specific relationship-focused principles and strategies and illustrate how these approaches can guide practice-research teams through the various sequential activities of the evaluation research process. In particular, it is suggested that practice-research collaborations can be formed, strengthened, and sustained by emphasis on a spirit of discovery and shared leadership at the start of the relationship, use of a comprehensive evaluation model to clarify and frame the evaluation and program goals, beginning where the client is when selecting research methodology and measurement tools, commitment to keeping the program first and recording everything during the implementation and data-collection stages, discussion of emerging findings and presentation of findings in graphic format at the data-analysis stage, and a total team approach at the dissemination stage.

  5. 49 CFR 212.101 - Program principles.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Program principles. 212.101 Section 212.101 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... principles. (a) The purpose of the national railroad safety program is to promote safety in all areas of...

  6. General Principles for Brain Design

    Science.gov (United States)

    Josephson, Brian D.

    2006-06-01

    The task of understanding how the brain works has met with only limited success since important design concepts are not as yet incorporated in the analysis. Relevant concepts can be uncovered by studying the powerful methodologies that have evolved in the context of computer programming, raising the question of how the concepts involved there can be realised in neural hardware. Insights can be gained in regard to such issues through the study of the role played by models and representation. These insights lead on to an appreciation of the mechanisms underlying subtle capacities such as those concerned with the use of language. A precise, essentially mathematical account of such capacities is in prospect for the future.

  7. Design Principles of Open Innovation Concept – Universal Design Viewpoint

    OpenAIRE

    Mustaquim, Moyen; Nyström, Tobias

    2013-01-01

    The concept of open innovation is becoming an increasingly popular topic of interest and seems to promise a lot in organizational development. However, to date there are no certain design principles that can be followed by organizations on how to use open innovation successfully. In this paper seven design principles of open innovation concept have been proposed. The derived principles are the outcome which is based on the principles of universal design. The open innovation design, based on t...

  8. Design Principles for Closed Loop Supply Chains

    NARCIS (Netherlands)

    H.R. Krikke (Harold); C.P. Pappis (Costas); G.T. Tsoulfas; J.M. Bloemhof-Ruwaard (Jacqueline)

    2001-01-01

    textabstractIn this paper we study design principles for closed loop supply chains. Closed loop supply chains aim at closing material flows thereby limiting emission and residual waste, but also providing customer service at low cost. We study 'traditional' and 'new' design principles known in the

  9. Design Principles for Fragment Libraries: Maximizing the Value of Learnings from Pharma Fragment-Based Drug Discovery (FBDD) Programs for Use in Academia.

    Science.gov (United States)

    Keserű, György M; Erlanson, Daniel A; Ferenczy, György G; Hann, Michael M; Murray, Christopher W; Pickett, Stephen D

    2016-09-22

    Fragment-based drug discovery (FBDD) is well suited for discovering both drug leads and chemical probes of protein function; it can cover broad swaths of chemical space and allows the use of creative chemistry. FBDD is widely implemented for lead discovery in industry but is sometimes used less systematically in academia. Design principles and implementation approaches for fragment libraries are continually evolving, and the lack of up-to-date guidance may prevent more effective application of FBDD in academia. This Perspective explores many of the theoretical, practical, and strategic considerations that occur within FBDD programs, including the optimal size, complexity, physicochemical profile, and shape profile of fragments in FBDD libraries, as well as compound storage, evaluation, and screening technologies. This compilation of industry experience in FBDD will hopefully be useful for those pursuing FBDD in academia.

  10. Principles for enabling deep secondary design

    DEFF Research Database (Denmark)

    Pries-Heje, Jan; Hansen, Magnus Rotvit Perlt

    2017-01-01

    design by analyzing two cases where secondary designers fundamentally change functionality, content and technology complexity level. The first case redesigns a decision model for agile development in an insurance company; the second creates a contingency model for choosing project management tools...... and techniques in a hospital. Our analysis of the two cases leads to the identification of four principles of design implementation that primary designers can apply to enable secondary design and four corresponding design implementation principles that secondary designers themselves need to apply....

  11. Justifying Design Decisions with Theory-based Design Principles

    OpenAIRE

    Schermann, Michael;Gehlert, Andreas;Pohl, Klaus;Krcmar, Helmut

    2014-01-01

    Although the role of theories in design research is recognized, we show that little attention has been paid on how to use theories when designing new artifacts. We introduce design principles as a new methodological approach to address this problem. Design principles extend the notion of design rationales that document how a design decision emerged. We extend the concept of design rationales by using theoretical hypotheses to support or object to design decisions. At the example of developing...

  12. Design principles for a large RFP experiment

    International Nuclear Information System (INIS)

    Phillpott, J.; Rostagni, G.; Di Marco, J.

    1981-01-01

    An RFP experiment (RFX) has been designed by an International Design Team, by groups of collaborating physicists and engineers working in their home laboratories. This international collaborative project has been brought to an advanced stage of system and component design by the co-operation of three design teams under the co-ordination of a Design Manager, based at Culham Laboratory. The paper summaries the important design principles for an RFP device, based on the outcome of this collaborative design project

  13. Towards agile large-scale predictive modelling in drug discovery with flow-based programming design principles.

    Science.gov (United States)

    Lampa, Samuel; Alvarsson, Jonathan; Spjuth, Ola

    2016-01-01

    Predictive modelling in drug discovery is challenging to automate as it often contains multiple analysis steps and might involve cross-validation and parameter tuning that create complex dependencies between tasks. With large-scale data or when using computationally demanding modelling methods, e-infrastructures such as high-performance or cloud computing are required, adding to the existing challenges of fault-tolerant automation. Workflow management systems can aid in many of these challenges, but the currently available systems are lacking in the functionality needed to enable agile and flexible predictive modelling. We here present an approach inspired by elements of the flow-based programming paradigm, implemented as an extension of the Luigi system which we name SciLuigi. We also discuss the experiences from using the approach when modelling a large set of biochemical interactions using a shared computer cluster.Graphical abstract.

  14. Game Design Principles based on Human Error

    Directory of Open Access Journals (Sweden)

    Guilherme Zaffari

    2016-03-01

    Full Text Available This paper displays the result of the authors’ research regarding to the incorporation of Human Error, through design principles, to video game design. In a general way, designers must consider Human Error factors throughout video game interface development; however, when related to its core design, adaptations are in need, since challenge is an important factor for fun and under the perspective of Human Error, challenge can be considered as a flaw in the system. The research utilized Human Error classifications, data triangulation via predictive human error analysis, and the expanded flow theory to allow the design of a set of principles in order to match the design of playful challenges with the principles of Human Error. From the results, it was possible to conclude that the application of Human Error in game design has a positive effect on player experience, allowing it to interact only with errors associated with the intended aesthetics of the game.

  15. Design Principles for Synthesizable Processor Cores

    DEFF Research Database (Denmark)

    Schleuniger, Pascal; McKee, Sally A.; Karlsson, Sven

    2012-01-01

    As FPGAs get more competitive, synthesizable processor cores become an attractive choice for embedded computing. Currently popular commercial processor cores do not fully exploit current FPGA architectures. In this paper, we propose general design principles to increase instruction throughput...

  16. MWH's water treatment: principles and design

    National Research Council Canada - National Science Library

    Crittenden, John C

    2012-01-01

    ... with additional worked problems and new treatment approaches. It covers both the principles and theory of water treatment as well as the practical considerations of plant design and distribution...

  17. Symbiotic architecture: Redefinition of recycling design principles

    OpenAIRE

    Milan Šijaković; Ana Perić

    2018-01-01

    The study seeks to examine the possibility of implementing the biological concept of symbiosis into the field of architecture for redefining the design principles of architectural recycling. Through an in-depth analysis of the biological concept of symbiosis (i.e., a close and often long-term interaction between two or more different biological species and the criteria that govern the differentiation between symbiotic associations), three redefined design principles of recycling—commensalism,...

  18. Team learning center design principles

    Energy Technology Data Exchange (ETDEWEB)

    Daily, B.; Loveland, J.; Whatley, A. [New Mexico State Univ., Las Cruces, NM (United States)] [and others

    1995-06-01

    This is a preliminary report of a multi-year collaboration of the authors addressing the subject: Can a facility be designed for team learning and would it improve the efficiency and effectiveness of team interactions? Team learning in this context is a broad definition that covers all activities where small to large groups of people come together to work, to learn, and to share through team activities. Multimedia, networking, such as World Wide Web and other tools, are greatly enhancing the capability of individual learning. This paper addresses the application of technology and design to facilitate group or team learning. Many organizational meetings need tens of people to come together to do work as a large group and then divide into smaller subgroups of five to ten to work and then to return and report and interact with the larger group. Current facilities were not, in general, designed for this type of meeting. Problems with current facilities are defined and a preliminary design solution to many of the identified problems is presented.

  19. Teaching geometrical principles to design students

    NARCIS (Netherlands)

    Feijs, L.M.G.; Bartneck, C.

    2009-01-01

    We propose a new method of teaching the principles of geometry to design students. The students focus on a field of design in which geometry is the design: tessellation. We review different approaches to geometry and the field of tessellation before we discuss the setup of the course. Instead of

  20. From qualification design to training design using ECVET principles

    International Nuclear Information System (INIS)

    Ceclan, Mihail; Wastin, Franck

    2017-01-01

    The Joint Research Centre of European Commission was designated in 2009 as Operating agent of European Human Resources Observatory - in Nuclear (EHRO@N). EHRO@N identified the nuclear sector's major challenges: to fill@in the 30 % gap between HR demand and supply in decommissioning and to adapt nuclear E and T system to comply more to the labour market demands. The process of nuclear training system adaptation to the labour market needs is based on the design of the flexible qualifications (unit based qualifications) using European Credit system for Vocational Education and Training (ECVET) principles. The process of ECVET implementation in the nuclear energy sector is ongoing since 2011 and is based on the strategy and road map developed by EHRO-N. The current paper presents the latest developments on the designing of training programs based on exit outcomes.

  1. From qualification design to training design using ECVET principles

    Energy Technology Data Exchange (ETDEWEB)

    Ceclan, Mihail; Wastin, Franck [European Commission Joint Research Centre, Petten (Netherlands). Directorate Nuclear Safety and Security

    2017-05-15

    The Joint Research Centre of European Commission was designated in 2009 as Operating agent of European Human Resources Observatory - in Nuclear (EHRO@N). EHRO@N identified the nuclear sector's major challenges: to fill@in the 30 % gap between HR demand and supply in decommissioning and to adapt nuclear E and T system to comply more to the labour market demands. The process of nuclear training system adaptation to the labour market needs is based on the design of the flexible qualifications (unit based qualifications) using European Credit system for Vocational Education and Training (ECVET) principles. The process of ECVET implementation in the nuclear energy sector is ongoing since 2011 and is based on the strategy and road map developed by EHRO-N. The current paper presents the latest developments on the designing of training programs based on exit outcomes.

  2. Construction principles of prevention programs for adolescents

    Directory of Open Access Journals (Sweden)

    A.A. Bochaver

    2014-08-01

    Full Text Available We present the basic principles for the development of effective programs for prevention of substance abuse among young people employed in the United States. They are based on the model of “risk factors and protective factors” and suggest a consistent, systematic, coordinated deployment of preventive interventions for children of different ages and in different social contexts (individually, in family, at school, in community. These principles can be useful for transfer of foreign experience on the Russian reality and for development of a new generation of programs for the prevention of substance abuse in Russia. Also, these principles and ideas may be partly extrapolated to develop prevention programs for other social risks.

  3. Design Principles for Augmented Reality Learning

    Science.gov (United States)

    Dunleavy, Matt

    2014-01-01

    Augmented reality is an emerging technology that utilizes mobile, context-aware devices (e.g., smartphones, tablets) that enable participants to interact with digital information embedded within the physical environment. This overview of design principles focuses on specific strategies that instructional designers can use to develop AR learning…

  4. Mechatronics design principles for biotechnology product development.

    Science.gov (United States)

    Mandenius, Carl-Fredrik; Björkman, Mats

    2010-05-01

    Traditionally, biotechnology design has focused on the manufacture of chemicals and biologics. Still, a majority of biotechnology products that appear on the market today is the result of mechanical-electric (mechatronic) construction. For these, the biological components play decisive roles in the design solution; the biological entities are either integral parts of the design, or are transformed by the mechatronic system. This article explains how the development and production engineering design principles used for typical mechanical products can be adapted to the demands of biotechnology products, and how electronics, mechanics and biology can be integrated more successfully. We discuss three emerging areas of biotechnology in which mechatronic design principles can apply: stem cell manufacture, artificial organs, and bioreactors. Copyright 2010 Elsevier Ltd. All rights reserved.

  5. Design Principles for Natural and Hybrid Ventilation

    OpenAIRE

    Heiselberg, Per

    2000-01-01

    For many years mechanical and natural ventilation systems have developed separately. Naturally, the next step in this development is the development of ventilation concepts that utilize and combine the best features from each system to create a new type of ventilation system- Hybrid Ventilation. The hybrid ventilation concepts, design challenges and principles are discussed and illustrated by four building examples.

  6. RFID Malware: Design Principles and Examples

    NARCIS (Netherlands)

    Rieback, M.R.; Simpson, P.N.D.; Crispo, B.; Tanenbaum, A.S.

    2006-01-01

    This paper explores the concept of malware for Radio Frequency Identification (RFID) systems - including RFID exploits, RFID worms, and RFID viruses. We present RFID malware design principles together with concrete examples; the highlight is a fully illustrated example of a self-replicating RFID

  7. Devising Principles of Design for Numeracy Tasks

    Science.gov (United States)

    Geiger, Vince; Forgasz, Helen; Goos, Merrilyn; Bennison, Anne

    2014-01-01

    Numeracy is a fundamental component of the Australian National Curriculum as a General Capability identified in each F-10 subject. In this paper, we consider the principles of design necessary for the development of numeracy tasks specific to subjects other than mathematics--in this case, the subject of English. We explore the nature of potential…

  8. Teaching geometrical principles to design students

    Directory of Open Access Journals (Sweden)

    Christoph Bartneck

    2009-12-01

    Full Text Available We propose a new method of teaching the principles of geometry to design students. The students focus on a field of design in which geometry is the design: tessellation. We review different approaches to geometry and the field of tessellation before we discuss the setup of the course. Instead of employing 2D drawing tools, such as Adobe Illustrator, the students define their tessellation in mathematical formulas, using the Mathematica software. This procedure enables them to understand the mathematical principles on which graphical tools, such as Illustrator are built upon. But we do not stop at a digital representation of their tessellation design we continue to cut their tessellations in Perspex. It moves the abstract concepts of math into the real world, so that the students can experience them directly, which provides a tremendous reward to the students.

  9. A survey of functional programming language principles

    Science.gov (United States)

    Holloway, C. M.

    1986-01-01

    Research in the area of functional programming languages has intensified in the 8 years since John Backus' Turing Award Lecture on the topic was published. The purpose of this paper is to present a survey of the ideas of functional programming languages. The paper assumes the reader is comfortable with mathematics and has knowledge of the basic principles of traditional programming languages, but does not assume any prior knowledge of the ideas of functional languages. A simple functional language is defined and used to illustrate the basic ideas. Topics discussed include the reasons for developing functional languages, methods of expressing concurrency, the algebra of functional programming languages, program transformation techniques, and implementations of functional languages. Existing functional languages are also mentioned. The paper concludes with the author's opinions as to the future of functional languages. An annotated bibliography on the subject is also included.

  10. Stochastic control theory dynamic programming principle

    CERN Document Server

    Nisio, Makiko

    2015-01-01

    This book offers a systematic introduction to the optimal stochastic control theory via the dynamic programming principle, which is a powerful tool to analyze control problems. First we consider completely observable control problems with finite horizons. Using a time discretization we construct a nonlinear semigroup related to the dynamic programming principle (DPP), whose generator provides the Hamilton–Jacobi–Bellman (HJB) equation, and we characterize the value function via the nonlinear semigroup, besides the viscosity solution theory. When we control not only the dynamics of a system but also the terminal time of its evolution, control-stopping problems arise. This problem is treated in the same frameworks, via the nonlinear semigroup. Its results are applicable to the American option price problem. Zero-sum two-player time-homogeneous stochastic differential games and viscosity solutions of the Isaacs equations arising from such games are studied via a nonlinear semigroup related to DPP (the min-ma...

  11. Human Factors Principles in Information Dashboard Design

    Energy Technology Data Exchange (ETDEWEB)

    Hugo, Jacques V.; St. Germain, Shawn

    2016-06-01

    strategic modernization program at a nuclear power plant where legacy systems are upgraded to advanced digital technologies through a systematic process that links human factors principles to the systems engineering process. This approach will help to create an integrated control room architecture beyond what is possible for individual subsystem upgrades alone. In addition, several human factors design and evaluation methods were used to develop the end-state concept, including interactive sessions with operators in INL’s Human System Simulation Laboratory, three-dimensional modeling to visualize control board changes.

  12. The Effect of a Computer Program Designed with Constructivist Principles for College Non-Science Majors on Understanding of Photosynthesis and Cellular Respiration

    Science.gov (United States)

    Wielard, Valerie Michelle

    2013-01-01

    The primary objective of this project was to learn what effect a computer program would have on academic achievement and attitude toward science of college students enrolled in a biology class for non-science majors. It became apparent that the instructor also had an effect on attitudes toward science. The researcher designed a computer program,…

  13. Macro-environmental policy: Principles and design

    International Nuclear Information System (INIS)

    Huppes, G.

    1993-01-01

    The central theme of this book is how macro-environmental policy can be developed, which does not prescribe or suggest specific technologies and products bu realizes the environmental quality desired by changing the general context. The publication is composed of four main parts. The framework for analysis and the normative principles for policy design and evaluation, the first two parts, form the analytic core. The framework for analysis gives a classification of instruments in terms of permutations of a limited number of defining elements. The normative principles guide choices in instrument design and, as the flexible response strategy, guide their application in specific policies. Detailing two main new instruments (the standard method for life cycle analysis and the substance deposit, and applying the instrument strategy as developed to the cases make up the next two parts

  14. Universal Instructional Design Principles for Moodle

    Directory of Open Access Journals (Sweden)

    Tanya Elias

    2010-05-01

    Full Text Available The paper identifies a set of universal instructional design (UID principles appropriate to distance education (DE and tailored to the needs of instructional designers and instructors teaching online. These principles are then used to assess the accessibility level of a sample online course and the availability of options in its LMS platform (Moodle to increase course accessibility. Numerous accessibility-sensitive plug-in modules are found to be available to Moodle users, though relatively few features were included in the sample course analysed. This may be because they have not been made available to instructors at the institutional level. The paper offers a series of recommendations to improve the accessibility of online DE to learners with diverse abilities, disabilities, and needs.

  15. Implantable biomedical microsystems design principles and applications

    CERN Document Server

    Bhunia, Swarup; Sawan, Mohamad

    2015-01-01

    Research and innovation in areas such as circuits, microsystems, packaging, biocompatibility, miniaturization, power supplies, remote control, reliability, and lifespan are leading to a rapid increase in the range of devices and corresponding applications in the field of wearable and implantable biomedical microsystems, which are used for monitoring, diagnosing, and controlling the health conditions of the human body. This book provides comprehensive coverage of the fundamental design principles and validation for implantable microsystems, as well as several major application areas. Each co

  16. Design Principles for E-Government Architectures

    Science.gov (United States)

    Sandoz, Alain

    The paper introduces a holistic approach for architecting systems which must sustain the entire e-government activity of a public authority. Four principles directly impact the architecture: Legality, Responsibility, Transparency, and Symmetry leading to coherent representations of the architecture for the client, the designer and the builder. The approach enables to deploy multipartite, distributed public services, including legal delegation of roles and outsourcing of non mandatory tasks through PPP.

  17. Cryostat design case studies, principles and engineering

    CERN Document Server

    2016-01-01

    This book enables the reader to learn the fundamental and applied aspects of practical cryostat design by examining previous design choices and resulting cryostat performance. Through a series of extended case studies the book presents an overview of existing cryostat design covering a wide range of cryostat types and applications, including the magnet cryostats that comprise the majority of the Large Hadron Collider at CERN, space-borne cryostats containing sensors operating below 1 K, and large cryogenic liquid storage vessels. It starts with an introductory section on the principles of cryostat design including practical data and equations. This section is followed by a series of case studies on existing cryostats, describing the specific requirements of the cryostat, the challenges involved and the design choices made along with the resulting performance of the cryostat. The cryostat examples used in the studies are chosen to cover a broad range of cryostat applications and the authors of each case are ...

  18. Y-12 Sustainable Design Principles for Building Design and Construction

    Energy Technology Data Exchange (ETDEWEB)

    Jackson, J. G.

    2008-11-01

    B&W Y-12 is committed to modernizing the Y-12 complex to meet future needs with a sustainable and responsive infrastructure and to integrating sustainability principles and practices into Y-12 work (Y72-001, B&W Y-12 Environmental, Safety and Health Policy). This commitment to sustainability and specifically sustainable design of buildings is also incorporated into Presidential Executive Orders (EO), DOE Orders (DOE O), and goals. Sustainable building design is an approach to design, construct, and operate facilities in an efficient and environmentally sound manner that will produce a healthful, resource-efficient and productive working environment that is inherently protective of the environment. The DOE has established the following 5 Guiding Principles for High Performance Sustainable Building (HPSB), and has issued directives that require Y-12 to incorporate the principles and a number of supporting specific practices and techniques into building design, construction and renovation projects: (1) Employ Integrated Design Principles; (2) Optimize Energy Performance; (3) Protect and Conserve Water; (4) Enhance Indoor Environmental Quality; and (5) Reduce Environmental Impact of Materials. The purpose of this document is to present the required sustainable building principles, practices and techniques, summarize the key drivers for incorporating them into Y-12 projects, and present additional recommendations and resources that can be used to support sustainable buildings to enhance the environmental and economic performance of the Y-12 Complex.

  19. Design Principles for Natural and Hybrid Ventilation

    DEFF Research Database (Denmark)

    Heiselberg, Per

    For many years mechanical and natural ventilation systems have developed separately. Naturally, the next step in this development is the development of ventilation concepts that utilize and combine the best features from each system to create a new type of ventilation system- Hybrid Ventilation. ....... The hybrid ventilation concepts, design challenges and principles are discussed and illustrated by four building examples.......For many years mechanical and natural ventilation systems have developed separately. Naturally, the next step in this development is the development of ventilation concepts that utilize and combine the best features from each system to create a new type of ventilation system- Hybrid Ventilation...

  20. Construction principles and design rules in the case of circular design

    NARCIS (Netherlands)

    Romme, A.G.L.; Endenburg, G.

    2006-01-01

    This paper proposes science-based organization design that uses construction principles and design rules to guide practitioner-academic projects. Organization science implies construction principles for creating and implementing designs. These principles serve to construct design rules that are

  1. Design and construction of a basic principle simulator: an experiment

    International Nuclear Information System (INIS)

    Fernandez, O.; Galdoz, E.; Flury, C.; Fontanini, H.; Maciel, F.; Rovere, L.; Carpio, R.

    1992-01-01

    This paper describes activities developed over design and building of a Basic Principle Simulator for nuclear power plants. This simulator has been developed in Process Control Division of Bariloche Atomic Center, Argentina. This project was sponsored jointly by CNEA and Atomic Energy International Organization, through the United Nations Program for Development. The paper specially emphasizes aspects like: architecture design methodology of real time simulators; graphic environment and interfaces design for users and instructor interaction, and for display information; test and validation of the used models; and human resources formation. Finally describes the actual implementation of the simulator to be used in Embalse Nuclear Power Plant. (author)

  2. Two Eyes, 3D: Stereoscopic Design Principles

    Science.gov (United States)

    Price, Aaron; Subbarao, M.; Wyatt, R.

    2013-01-01

    Two Eyes, 3D is a NSF-funded research project about how people perceive highly spatial objects when shown with 2D or stereoscopic ("3D") representations. As part of the project, we produced a short film about SN 2011fe. The high definition film has been rendered in both 2D and stereoscopic formats. It was developed according to a set of stereoscopic design principles we derived from the literature and past experience producing and studying stereoscopic films. Study participants take a pre- and post-test that involves a spatial cognition assessment and scientific knowledge questions about Type-1a supernovae. For the evaluation, participants use iPads in order to record spatial manipulation of the device and look for elements of embodied cognition. We will present early results and also describe the stereoscopic design principles and the rationale behind them. All of our content and software is available under open source licenses. More information is at www.twoeyes3d.org.

  3. Design principles for robust oscillatory behavior.

    Science.gov (United States)

    Castillo-Hair, Sebastian M; Villota, Elizabeth R; Coronado, Alberto M

    2015-09-01

    Oscillatory responses are ubiquitous in regulatory networks of living organisms, a fact that has led to extensive efforts to study and replicate the circuits involved. However, to date, design principles that underlie the robustness of natural oscillators are not completely known. Here we study a three-component enzymatic network model in order to determine the topological requirements for robust oscillation. First, by simulating every possible topological arrangement and varying their parameter values, we demonstrate that robust oscillators can be obtained by augmenting the number of both negative feedback loops and positive autoregulations while maintaining an appropriate balance of positive and negative interactions. We then identify network motifs, whose presence in more complex topologies is a necessary condition for obtaining oscillatory responses. Finally, we pinpoint a series of simple architectural patterns that progressively render more robust oscillators. Together, these findings can help in the design of more reliable synthetic biomolecular networks and may also have implications in the understanding of other oscillatory systems.

  4. The new international certification and design principles

    International Nuclear Information System (INIS)

    Heijnen, W.H.P.M.; Heineman, H.

    1995-01-01

    ISO/TC 67 deals with standardization of Equipment for the Petroleum and Natural Gas Industries at a global level. The paper will provide the reader with insight in the Certification system as well as its link with Design. It will explain how the total process fits in the business structure of the Petroleum and Natural Gas Industry, with the focus on the emerging concepts such as partnering, turn key contracts, the developments in the EC and the need to reduce costs at a global basis. The paper will also address the topic of Design Principles based on the results of the study performed for ISO/TC 67. The paper will provide a framework that can be used by the industry in how to deal with issues such as, there shall the activity of the Operator be focused on when ordering equipment or services and how the manufacturer or service provider should prepare himself to become an equal partner with regard to the required equipment, service and its associated technology now and in the future. In the changing world with ever increasing focus on Health, Safety and Environment (HSE), the topic efficiency, technology, equipment performance and functionality should not be overlooked or been given less attention. The Certification and Design principles, implemented in standards, aim predominantly at Fitness for Purpose of equipment and/or services to regain the balance. A further aim is to limit consequential costs due to deficiencies in the broadest sense, allowing the Petroleum and Natural Gas Industry to produce oil and gas in a cost effective manner with the highest possible HSE targets

  5. Novel Natural Convection Heat Sink Design Concepts From First Principles

    Science.gov (United States)

    2016-06-01

    CONVECTION HEAT SINK DESIGN CONCEPTS FROM FIRST PRINCIPLES by Derek E. Fletcher June 2016 Thesis Advisor: Garth Hobson Second Reader...COVERED Master’s Thesis 4. TITLE AND SUBTITLE NOVEL NATURAL CONVECTION HEAT SINK DESIGN CONCEPTS FROM FIRST PRINCIPLES 5. FUNDING NUMBERS 6...CONVECTION HEAT SINK DESIGN CONCEPTS FROM FIRST PRINCIPLES Derek E. Fletcher Lieutenant Commander, United States Navy B.S., Southwestern

  6. Basic design principles of colorimetric vision systems

    Science.gov (United States)

    Mumzhiu, Alex M.

    1998-10-01

    Color measurement is an important part of overall production quality control in textile, coating, plastics, food, paper and other industries. The color measurement instruments such as colorimeters and spectrophotometers, used for production quality control have many limitations. In many applications they cannot be used for a variety of reasons and have to be replaced with human operators. Machine vision has great potential for color measurement. The components for color machine vision systems, such as broadcast quality 3-CCD cameras, fast and inexpensive PCI frame grabbers, and sophisticated image processing software packages are available. However the machine vision industry has only started to approach the color domain. The few color machine vision systems on the market, produced by the largest machine vision manufacturers have very limited capabilities. A lack of understanding that a vision based color measurement system could fail if it ignores the basic principles of colorimetry is the main reason for the slow progress of color vision systems. the purpose of this paper is to clarify how color measurement principles have to be applied to vision systems and how the electro-optical design features of colorimeters have to be modified in order to implement them for vision systems. The subject of this presentation far exceeds the limitations of a journal paper so only the most important aspects will be discussed. An overview of the major areas of applications for colorimetric vision system will be discussed. Finally, the reasons why some customers are happy with their vision systems and some are not will be analyzed.

  7. Framework for assessing causality in disease management programs: principles.

    Science.gov (United States)

    Wilson, Thomas; MacDowell, Martin

    2003-01-01

    To credibly state that a disease management (DM) program "caused" a specific outcome it is required that metrics observed in the DM population be compared with metrics that would have been expected in the absence of a DM intervention. That requirement can be very difficult to achieve, and epidemiologists and others have developed guiding principles of causality by which credible estimates of DM impact can be made. This paper introduces those key principles. First, DM program metrics must be compared with metrics from a "reference population." This population should be "equivalent" to the DM intervention population on all factors that could independently impact the outcome. In addition, the metrics used in both groups should use the same defining criteria (ie, they must be "comparable" to each other). The degree to which these populations fulfill the "equivalent" assumption and metrics fulfill the "comparability" assumption should be stated. Second, when "equivalence" or "comparability" is not achieved, the DM managers should acknowledge this fact and, where possible, "control" for those factors that may impact the outcome(s). Finally, it is highly unlikely that one study will provide definitive proof of any specific DM program value for all time; thus, we strongly recommend that studies be ongoing, at multiple points in time, and at multiple sites, and, when observational study designs are employed, that more than one type of study design be utilized. Methodologically sophisticated studies that follow these "principles of causality" will greatly enhance the reputation of the important and growing efforts in DM.

  8. Personnel Selection Using Fuzzy Axiomatic Design Principles

    Directory of Open Access Journals (Sweden)

    Anant V. Khandekar

    2016-09-01

    Full Text Available Overall competency of the working personnel is often observed to ultimately affect the productivity of an organization. The globalised competitive atmosphere coupled with technological improvements demands for efficient and specialized manpower for the industrial operations. A set of typical technological skills and attitudes is thus demanded for every job profile. Most often, these skills and attitudes are expressed imprecisely and hence, necessitating the support of fuzzy sets for their effective understanding and further processing. In this paper, a method based on fuzzy axiomatic design principles is applied for solving the personnel selection problems. Selecting a middle management staff of a service department for a large scale organization is demonstrated here as a real life example. Five shortlisted candidates are assessed with respect to a set of 18 evaluation criteria, and the selection committee with experts from the related fields also realizes the outcome of the adopted approach to be quite appropriate, befitting and in agreement with their expectations.

  9. Integrating Quality Matters into Hybrid Course Design: A Principles of Marketing Case Study

    Science.gov (United States)

    Young, Mark R.

    2014-01-01

    Previous research supports the idea that the success of hybrid or online delivery modes is more a function of course design than delivery media. This article describes a case study of a hybrid Principles of Marketing course that implemented a comprehensive redesign based on design principles espoused by the Quality Matters Program, a center for…

  10. Materials design principles of ancient fish armour

    Science.gov (United States)

    Bruet, Benjamin J. F.; Song, Juha; Boyce, Mary C.; Ortiz, Christine

    2008-09-01

    Knowledge of the structure-property-function relationships of dermal scales of armoured fish could enable pathways to improved bioinspired human body armour, and may provide clues to the evolutionary origins of mineralized tissues. Here, we present a multiscale experimental and computational approach that reveals the materials design principles present within individual ganoid scales from the `living fossil' Polypterus senegalus. This fish belongs to the ancient family Polypteridae, which first appeared 96 million years ago during the Cretaceous period and still retains many of their characteristics. The mechanistic origins of penetration resistance (approximating a biting attack) were investigated and found to include the juxtaposition of multiple distinct reinforcing composite layers that each undergo their own unique deformation mechanisms, a unique spatial functional form of mechanical properties with regions of differing levels of gradation within and between material layers, and layers with an undetectable gradation, load-dependent effective material properties, circumferential surface cracking, orthogonal microcracking in laminated sublayers and geometrically corrugated junctions between layers.

  11. Theory-Generating Practice: Proposing a principle for learning design

    Directory of Open Access Journals (Sweden)

    Mie Buhl

    2016-06-01

    Full Text Available This contribution proposes a principle for learning design: Theory-Generating Practice (TGP as an alternative to the way university courses often are taught and structured with a series of theoretical lectures separate from practical experience and concluding with an exam or a project. The aim is to contribute to a development of theoretical frameworks for learning designs by suggesting TGP which may lead to new practices and turn the traditional dramaturgy for teaching upside down. TGP focuses on embodied experience prior to text reading and lectures to enhance theoretical knowledge building and takes tacit knowledge into account. The article introduces TGP and contextualizes it to a Danish tradition of didactics as well as discusses it in relation to contemporary conceptual currents of didactic design and learning design. This is followed by a theoretical framing of TGP, and is discussed through three empirical examples from bachelor and master programs involving technology, and showing three ways of practicing it.

  12. Theory-Generating Practice: Proposing a principle for learning design

    Directory of Open Access Journals (Sweden)

    Mie Buhl

    2016-05-01

    Full Text Available This contribution proposes a principle for learning design: Theory-Generating Practice (TGP as an alternative to the way university courses often are taught and structured with a series of theoretical lectures separate from practical experience and concluding with an exam or a project. The aim is to contribute to a development of theoretical frameworks for learning designs by suggesting TGP which may lead to new practices and turn the traditional dramaturgy for teaching upside down. TGP focuses on embodied experience prior to text reading and lectures to enhance theoretical knowledge building and takes tacit knowledge into account. The article introduces TGP and contextualizes it to a Danish tradition of didactics as well as discusses it in relation to contemporary conceptual currents of didactic design and learning design. This is followed by a theoretical framing of TGP, and is discussed through three empirical examples from bachelor and master programs involving technology, and showing three ways of practicing it.

  13. Using the principles of circadian physiology enhances shift schedule design

    International Nuclear Information System (INIS)

    Connolly, J.J.; Moore-Ede, M.C.

    1987-01-01

    Nuclear power plants must operate 24 h, 7 days a week. For the most part, shift schedules currently in use at nuclear power plants have been designed to meet operational needs without considering the biological clocks of the human operators. The development of schedules that also take circadian principles into account is a positive step that can be taken to improve plant safety by optimizing operator alertness. These schedules reduce the probability of human errors especially during backshifts. In addition, training programs that teach round-the-clock workers how to deal with the problems of shiftwork can help to optimize performance and alertness. These programs teach shiftworkers the underlying causes of the sleep problems associated with shiftwork and also provide coping strategies for improving sleep and dealing with the transition between shifts. When these training programs are coupled with an improved schedule, the problems associated with working round-the-clock can be significantly reduced

  14. Principles for Promoting the Financial Sustainability of Online Programs

    Science.gov (United States)

    Meyer, Katrina A.; Bruwelheide, Janis; Poulin, Russell

    2009-01-01

    The project described in this article was an attempt to uncover the principles of financial sustainability for online programs and to align these with a guide to managing online programs. An initial team of experienced online educators developed draft principles, which were then reviewed by an external consultant and revised; the revised…

  15. Earth Science Principles Pertinent to the General Education Programs in Junior High Schools

    Science.gov (United States)

    Henson, Kenneth Tyrone

    1970-01-01

    Presents the procedures, and findings of a study designed to identify principles in astronomy, geology, meterology, oceanography and physical geography pertinent to general education programs in junior high schools. (LC)

  16. Preserving SSC Design Function Using RCM Principles

    International Nuclear Information System (INIS)

    Mohammadi, K.

    2009-01-01

    Reliability-Centered Maintenance (RCM) can be defined as an approach that employs preventive, predictive, proactive, and reactive maintenance practices and strategies in an integrated manner to increase the probability that a Structure, System, or Component (SSC) will function as designed over its life cycle with optimum maintenance. The goal of RCM is to preserve the SSC intended design function at the lowest cost by developing a maintenance strategy that is supported by sound technical and economic justification. RCM has been used extensively by the aircraft, space, defense, power generation, and manufacturing industries where functional failures of SSCs can have the potential to compromise worker or public safety, cause adverse environmental impact, cause loss of production, and/or result in excessive damage to critical SSCs. This paper provides a framework for performing an RCM analysis in support of DOE Order 430.1A (Life Cycle Asset Management) and DOE Order 420.1B (Facility Safety). The influence of RCM on the various aspects of the maintenance program including the work control process is also discussed

  17. Designing computer programs

    CERN Document Server

    Haigh, Jim

    1994-01-01

    This is a book for students at every level who are learning to program for the first time - and for the considerable number who learned how to program but were never taught to structure their programs. The author presents a simple set of guidelines that show the programmer how to design in a manageable structure from the outset. The method is suitable for most languages, and is based on the widely used 'JSP' method, to which the student may easily progress if it is needed at a later stage.Most language specific texts contain very little if any information on design, whilst books on des

  18. Design principles for engaging and retaining virtual citizen scientists.

    Science.gov (United States)

    Wald, Dara M; Longo, Justin; Dobell, A R

    2016-06-01

    Citizen science initiatives encourage volunteer participants to collect and interpret data and contribute to formal scientific projects. The growth of virtual citizen science (VCS), facilitated through websites and mobile applications since the mid-2000s, has been driven by a combination of software innovations and mobile technologies, growing scientific data flows without commensurate increases in resources to handle them, and the desire of internet-connected participants to contribute to collective outputs. However, the increasing availability of internet-based activities requires individual VCS projects to compete for the attention of volunteers and promote their long-term retention. We examined program and platform design principles that might allow VCS initiatives to compete more effectively for volunteers, increase productivity of project participants, and retain contributors over time. We surveyed key personnel engaged in managing a sample of VCS projects to identify the principles and practices they pursued for these purposes and led a team in a heuristic evaluation of volunteer engagement, website or application usability, and participant retention. We received 40 completed survey responses (33% response rate) and completed a heuristic evaluation of 20 VCS program sites. The majority of the VCS programs focused on scientific outcomes, whereas the educational and social benefits of program participation, variables that are consistently ranked as important for volunteer engagement and retention, were incidental. Evaluators indicated usability, across most of the VCS program sites, was higher and less variable than the ratings for participant engagement and retention. In the context of growing competition for the attention of internet volunteers, increased attention to the motivations of virtual citizen scientists may help VCS programs sustain the necessary engagement and retention of their volunteers. © 2016 Society for Conservation Biology.

  19. Programming principles and practice using C++

    CERN Document Server

    Stroustrup, Bjarne

    2014-01-01

    An Introduction to Programming by the Inventor of C++ Preparation for Programming in the Real World The book assumes that you aim eventually to write non-trivial programs, whether for work in software development or in some other technical field. Focus on Fundamental Concepts and Techniques The book explains fundamental concepts and techniques in greater depth than traditional introductions. This approach will give you a solid foundation for writing useful, correct, maintainable, and efficient code. Programming with Today's C++ (C++11 and C++14) The book is an introduction to programming in general, including object-oriented programming and generic programming. It is also a solid introduction to the C++ programming language, one of the most widely used languages for real-world software. The book presents modern C++ programming techniques from the start, introducing the C++ standard library and C++11 and C++14 features to simplify programming tasks. For Beginners-And Anyone Who Wants to Learn Something New The...

  20. General design safety principles for nuclear power plants

    International Nuclear Information System (INIS)

    1986-01-01

    This Safety Guide provides the safety principles and the approach that have been used to implement the Code in the Safety Guides. These safety principles and the approach are tied closely to the safety analyses needed to assist the design process, and are used to verify the adequacy of nuclear power plant designs. This Guide also provides a framework for the use of other design Safety Guides. However, although it explains the principles on which the other Safety Guides are based, the requirements for specific applications of these principles are mostly found in the other Guides

  1. Human Systems Interface Design Methods Using Ecological Interface Design Principles

    International Nuclear Information System (INIS)

    Hong, Seung Kweon; Park, Jung Chul; Kim, Sun Su; Sim, Kwang Pyo; Yuk, Seung Yul; Choi, Jae Hyeon; Yoon, Seung Hyun

    2009-12-01

    The results of this study categorized into two parts. The first part is the guidelines for EID designs. The procedure to observe for EID design is composed of 6 steps; 1) to define a target system, 2) to make an abstraction hierarchy model, 3) to check the link structure among each components included in the layers of abstraction hierarchy model, 4) to transform information requirements to variables, 5) to make the graphs related to each variables, 6) to check the graphs by visual display design principles and heuristic rules. The second part is an EID design alternative for nuclear power plant. The EID for high level function represents the energy balance and energy flow in each loop of nuclear power plant. The EID for middle level function represents the performance indicators of each equipment involved in the all processes of changing from coolants to steam. The EID for low level function represents the values measured in each equipment such as temperature, pressure, water level and so on

  2. Safety principles and design management of Chashma Nuclear Power Plant

    International Nuclear Information System (INIS)

    Geng Qirui; Cheng Pingdong

    1997-01-01

    The basic safety consideration and detailed design principles in the design of Chashma Nuclear Power Plant is elaborated. The management within the frame setting up by 'safety culture' and 'quality culture'

  3. EVALUATION OF STREET FURNITURE ACCORDING TO BASIC DESIGN PRINCIPLES

    OpenAIRE

    GHORAB, Peyman; YÜCEL CAYMAZ, Gökçen Firdevs

    2014-01-01

    In the urban context, it is important to create more comfortable and livable environments with proper planning, design and application. Because aesthetic considerations are of more importance today, designing urban furniture to give a more beautiful appearance to cities is of high priority; designers and those working in related disciplines must be careful to observe these principles throughout the design process. This paper describes research conducted to review the aesthetic principles invo...

  4. The Value of the Operational Principle in Instructional Design

    Science.gov (United States)

    Gibbons, Andrew S.

    2009-01-01

    Formal design studies are increasing our insight into design processes, including those of instructional design. Lessons are being learned from other design fields, and new techniques and concepts can be imported as they are demonstrated effective. The purpose of this article is to introduce a design concept--the "operational principle"--for…

  5. Enhancing the Therapy Experience Using Principles of Video Game Design.

    Science.gov (United States)

    Folkins, John Wm; Brackenbury, Tim; Krause, Miriam; Haviland, Allison

    2016-02-01

    This article considers the potential benefits that applying design principles from contemporary video games may have on enhancing therapy experiences. Six principles of video game design are presented, and their relevance for enriching clinical experiences is discussed. The motivational and learning benefits of each design principle have been discussed in the education literature as having positive impacts on student motivation and learning and are related here to aspects of clinical practice. The essential experience principle suggests connecting all aspects of the experience around a central emotion or cognitive connection. The discovery principle promotes indirect learning in focused environments. The risk-taking principle addresses the uncertainties clients face when attempting newly learned skills in novel situations. The generalization principle encourages multiple opportunities for skill transfer. The reward system principle directly relates to the scaffolding of frequent and varied feedback in treatment. Last, the identity principle can assist clients in using their newly learned communication skills to redefine self-perceptions. These principles highlight areas for research and interventions that may be used to reinforce or advance current practice.

  6. Floyd's principle, correctness theories and program equivalence

    NARCIS (Netherlands)

    Bergstra, J.A.; Tiuryn, J.; Tucker, J.V.

    1982-01-01

    A programming system is a language made from a fixed class of data abstractions and a selection of familiar deterministic control and assignment constructs. It is shown that the sets of all ‘before-after’ first-order assertions which are true of programs in any such language can uniquely determine

  7. Architectural design of heterogeneous metallic nanocrystals--principles and processes.

    Science.gov (United States)

    Yu, Yue; Zhang, Qingbo; Yao, Qiaofeng; Xie, Jianping; Lee, Jim Yang

    2014-12-16

    CONSPECTUS: Heterogeneous metal nanocrystals (HMNCs) are a natural extension of simple metal nanocrystals (NCs), but as a research topic, they have been much less explored until recently. HMNCs are formed by integrating metal NCs of different compositions into a common entity, similar to the way atoms are bonded to form molecules. HMNCs can be built to exhibit an unprecedented architectural diversity and complexity by programming the arrangement of the NC building blocks ("unit NCs"). The architectural engineering of HMNCs involves the design and fabrication of the architecture-determining elements (ADEs), i.e., unit NCs with precise control of shape and size, and their relative positions in the design. Similar to molecular engineering, where structural diversity is used to create more property variations for application explorations, the architectural engineering of HMNCs can similarly increase the utility of metal NCs by offering a suite of properties to support multifunctionality in applications. The architectural engineering of HMNCs calls for processes and operations that can execute the design. Some enabling technologies already exist in the form of classical micro- and macroscale fabrication techniques, such as masking and etching. These processes, when used singly or in combination, are fully capable of fabricating nanoscopic objects. What is needed is a detailed understanding of the engineering control of ADEs and the translation of these principles into actual processes. For simplicity of execution, these processes should be integrated into a common reaction system and yet retain independence of control. The key to architectural diversity is therefore the independent controllability of each ADE in the design blueprint. The right chemical tools must be applied under the right circumstances in order to achieve the desired outcome. In this Account, after a short illustration of the infinite possibility of combining different ADEs to create HMNC design

  8. Principle design and data of graphite components

    International Nuclear Information System (INIS)

    Ishihara, Masahiro; Sumita, Junya; Shibata, Taiju; Iyoku, Tatsuo; Oku, Tatsuo

    2004-01-01

    The High Temperature Engineering Test Reactor (HTTR) constructed by Japan Atomic Energy Research Institute (JAERI) is a graphite-moderated and helium-gas-cooled reactor with prismatic fuel elements of hexagonal blocks. The reactor internal structures of the HTTR are mainly made up of graphite components. As well known, the graphite is a brittle material and there were no available design criteria for brittle materials. Therefore, JAERI had to develop the design criteria taking account of the brittle fracture behavior. In this paper, concept and key specification of the developed graphite design criteria is described, and also an outline of the quality control specified in the design criteria is mentioned

  9. Urban Environment Development based on Universal Design Principles

    Science.gov (United States)

    Harsritanto, Bangun Ir

    2018-02-01

    Universal Design is a design which facilitated full range of human diversity. By applying Universal design principles, urban environment can be more functional and more user-friendly for everyone. This study examined five urban streets of South Korea as a country experienced on developing various urban street designs based on universal design. This study aimed to examine and compare the South Korea cases using seven principles of universal design. The research methods of this study are literature study, case study, and site observation. The results of this study are: South Korea cases are good practices, urgency of implementing the direction into local regulations; and change of urban development paradigm.

  10. Toward Instructional Design Principles: Inducing Faraday's Law with Contrasting Cases

    Science.gov (United States)

    Kuo, Eric; Wieman, Carl E.

    2016-01-01

    Although physics education research (PER) has improved instructional practices, there are not agreed upon principles for designing effective instructional materials. Here, we illustrate how close comparison of instructional materials could support the development of such principles. Specifically, in discussion sections of a large, introductory…

  11. Design Principles for Achieving Integrated Healthcare Information Systems

    DEFF Research Database (Denmark)

    Jensen, Tina Blegind

    2013-01-01

    and Lyytinen, to examine the design principles that facilitated this smallscale project to expand and become widespread. As a result of my findings, I outline three lessons learned that emphasize: (i) principles of flexibility, (ii) expansion from the installed base through modular strategies and (iii...

  12. Publish Subscribe Systems Design and Principles

    CERN Document Server

    Tarkoma, Sasu

    2012-01-01

    This book offers an unified treatment of the problems solved by publish/subscribe, how to design and implement the solutions In this book, the author provides an insight into the publish/subscribe technology including the design, implementation, and evaluation of new systems based on the technology.  The book also addresses the basic design patterns and solutions, and discusses their application in practical application scenarios. Furthermore, the author examines current standards and industry best practices as well as recent research proposals in the area. Finally, necessary content ma

  13. MWH's water treatment: principles and design

    National Research Council Canada - National Science Library

    Crittenden, John C

    2012-01-01

    .... The contents have been updated to cover changes to regulatory requirements, testing methodology, and design approaches, as well as the emergent topics of pharmacological agents in the water supply...

  14. Design principles of electrical synaptic plasticity.

    Science.gov (United States)

    O'Brien, John

    2017-09-08

    Essentially all animals with nervous systems utilize electrical synapses as a core element of communication. Electrical synapses, formed by gap junctions between neurons, provide rapid, bidirectional communication that accomplishes tasks distinct from and complementary to chemical synapses. These include coordination of neuron activity, suppression of voltage noise, establishment of electrical pathways that define circuits, and modulation of high order network behavior. In keeping with the omnipresent demand to alter neural network function in order to respond to environmental cues and perform tasks, electrical synapses exhibit extensive plasticity. In some networks, this plasticity can have dramatic effects that completely remodel circuits or remove the influence of certain cell types from networks. Electrical synaptic plasticity occurs on three distinct time scales, ranging from milliseconds to days, with different mechanisms accounting for each. This essay highlights principles that dictate the properties of electrical coupling within networks and the plasticity of the electrical synapses, drawing examples extensively from retinal networks. Copyright © 2017 The Author. Published by Elsevier B.V. All rights reserved.

  15. Principles of waveform diversity and design

    CERN Document Server

    Wicks, Michael

    2011-01-01

    This is the first book to discuss current and future applications of waveform diversity and design in subjects such as radar and sonar, communications systems, passive sensing, and many other technologies. Waveform diversity allows researchers and system designers to optimize electromagnetic and acoustic systems for sensing, communications, electronic warfare or combinations thereof. This book enables solutions to problems, explaining how each system performs its own particular function, as well as how it is affected by other systems and how those other systems may likewise be affected. It is

  16. Design principles for radiological protection instrumentation systems

    International Nuclear Information System (INIS)

    Wells, F.H.; Powell, R.G.

    1981-02-01

    This Code of Practice takes the form of recommendations intended for designers and installers of Radiological Protection Instrumentation, and should also be of value to the newcomer to the R.P.I. field. Topics are discussed under the following headings: outline of R.P.I. requirements, specifying the requirement, satisfying the requirements, (overall design, availability and reliability, information display, human factors, power supplies, manufacture, quality assurance, testing, and cost analysis), supply, location and operation of the equipment, importance of documentation. (U.K.)

  17. Safety principles and design criteria for nuclear power stations

    International Nuclear Information System (INIS)

    Gazit, M.

    1982-01-01

    The criteria and safety principles for the design of nuclear power stations are presented from the viewpoint of a nuclear engineer. The design, construction and operation of nuclear power stations should be carried out according to these criteria and safety principles to ensure, to a reasonable degree, that the likelihood of release of radioactivity as a result of component failure or human error should be minimized. (author)

  18. Seven principles to design for embodied sensemaking

    NARCIS (Netherlands)

    Hummels, C.C.M.; Dijk, van J.

    2015-01-01

    The TEI-community is based a various paradigms. We believe that the community matures by scrutinising these different paradigms and unravelling the consequences for designing for tangible, embedded and embodied interaction. In this paper we explore the consequences and possibilities of

  19. Wireless sensor networks principles, design and applications

    CERN Document Server

    Yang, Shuang-Hua

    2014-01-01

    Wireless Sensor Networks presents the latest practical solutions to the design issues presented in wireless-sensor-network-based systems. Novel features of the text, distributed throughout, include workable solutions, demonstration systems and case studies of the design and application of wireless sensor networks (WSNs) based on the first-hand research and development experience of the author, and the chapters on real applications: building fire safety protection; smart home automation; and logistics resource management. Case studies and applications illustrate the practical perspectives of: ·         sensor node design; ·         embedded software design; ·         routing algorithms; ·         sink node positioning; ·         co-existence with other wireless systems; ·         data fusion; ·         security; ·         indoor location tracking; ·         integrating with radio-frequency identification; and ·         In...

  20. Design Principles for a Comprehensive Library System.

    Science.gov (United States)

    Uluakar, Tamer; And Others

    1981-01-01

    Describes an online design featuring circulation control, catalog access, and serial holdings that uses an incremental approach to system development. Utilizing a dedicated computer, this second of three releases pays particular attention to present and predicted computing capabilities as well as trends in library automation. (Author/RAA)

  1. Analysis of School Food Safety Programs Based on HACCP Principles

    Science.gov (United States)

    Roberts, Kevin R.; Sauer, Kevin; Sneed, Jeannie; Kwon, Junehee; Olds, David; Cole, Kerri; Shanklin, Carol

    2014-01-01

    Purpose/Objectives: The purpose of this study was to determine how school districts have implemented food safety programs based on HACCP principles. Specific objectives included: (1) Evaluate how schools are implementing components of food safety programs; and (2) Determine foodservice employees food-handling practices related to food safety.…

  2. Design principles for global commons: Natural resources and emerging technologies

    Directory of Open Access Journals (Sweden)

    Paul C. Stern

    2011-09-01

    Full Text Available Ostrom’s design principles for managing common pool resources were developed largely by examining local commons involving natural resources. This paper enumerates several key characteristics that distinguish such commons from more complex commons involving global resources and the risks of emerging technologies. It considers the degree to which the design principles transfer to those commons and concludes that although they have considerable external validity, the list needs some modification and elaboration to apply to global resources and risk commons. A list of design principles is offered for global resource commons and the risks of emerging technologies. Applying Ostrom’s approach to global resources and emerging technologies can improve understanding and expand the solution set for these problems from international treaties, top-down national regulation, and interventions in market pricing systems to include non-governmental institutions that embody principles of self-governance.

  3. Seven principle of highly effective Nuclear Energy Programs

    International Nuclear Information System (INIS)

    Ferguson, Ch.D.; Reed, Ph.D.

    2010-01-01

    This paper presents seven principles that demand consideration for any country using a nuclear power program or wanting to acquire such a program. These principles are assessing the overall energy system, determining effective use of financial resources for energy development, ensuring high safety standards, implementing best security practices, preventing the spread of nuclear weapons, managing radioactive waste in a safe and secure manner, and enacting a legal framework that encompasses the other principle areas. The paper applies management methods that underscore development of strong independent national capabilities integrated within an interdependent international system. The paper discusses the individual responsibilities of states in all seven principles and offers recommendations for how states can benefit from greater international cooperation in nuclear energy development

  4. Wind turbine technology principles and design

    CERN Document Server

    Adaramola, Muyiwa

    2014-01-01

    IntroductionPart I: AerodynamicsWind Turbine Blade Design; Peter J. Schubel and Richard J. CrossleyA Shrouded Wind Turbine Generating High Output Power with Wind-Lens Technology; Yuji Ohya and Takashi KarasudaniEcomoulding of Composite Wind Turbine Blades Using Green Manufacturing RTM Process; Brahim AttafAerodynamic Shape Optimization of a Vertical-Axis Wind Turbine Using Differential Evolution; Travis J. Carrigan, Brian H. Dennis, Zhen X. Han, and Bo P. WangPart II: Generators and Gear Systems

  5. Fuel cells principles, design, and analysis

    CERN Document Server

    Revankar, Shripad T

    2014-01-01

    ""This book covers all essential themes of fuel cells ranging from fundamentals to applications. It includes key advanced topics important for understanding correctly the underlying multi-science phenomena of fuel cell processes. The book does not only cope with traditional fuel cells but also discusses the future concepts of fuel cells. The book is rich on examples and solutions important for applying the theory into practical use.""-Peter Lund, Aalto University, Helsinki""A good introduction to the range of disciplines needed to design, build and test fuel cells.""-Nigel Brandon, Imperial Co

  6. Design principles of metal-cutting machine tools

    CERN Document Server

    Koenigsberger, F

    1964-01-01

    Design Principles of Metal-Cutting Machine Tools discusses the fundamentals aspects of machine tool design. The book covers the design consideration of metal-cutting machine, such as static and dynamic stiffness, operational speeds, gearboxes, manual, and automatic control. The text first details the data calculation and the general requirements of the machine tool. Next, the book discusses the design principles, which include stiffness and rigidity of the separate constructional elements and their combined behavior under load, as well as electrical, mechanical, and hydraulic drives for the op

  7. Geometry Design, Principles and Assembly of Micromotors

    Directory of Open Access Journals (Sweden)

    Huanpo Ning

    2018-02-01

    Full Text Available Discovery of bio-inspired, self-propelled and externally-powered nano-/micro-motors, rotors and engines (micromachines is considered a potentially revolutionary paradigm in nanoscience. Nature knows how to combine different elements together in a fluidic state for intelligent design of nano-/micro-machines, which operate by pumping, stirring, and diffusion of their internal components. Taking inspirations from nature, scientists endeavor to develop the best materials, geometries, and conditions for self-propelled motion, and to better understand their mechanisms of motion and interactions. Today, microfluidic technology offers considerable advantages for the next generation of biomimetic particles, droplets and capsules. This review summarizes recent achievements in the field of nano-/micromotors, and methods of their external control and collective behaviors, which may stimulate new ideas for a broad range of applications.

  8. Basic principles governing the design of magnetic switches

    International Nuclear Information System (INIS)

    Birx, D.L.; Lauer, E.J.; Reginato, L.L.; Schmidt, J.; Smith, M.

    1980-01-01

    The idea of using saturable reactors as the basis of high power pulse generators is not a new concept, but there have been few recent applications of this technology. Here the principle of magnetic pulse generation is briefly described and some of the basic guidelines used to design these circuits are discussed. A demonstration of the principles by a small scale pulse amplifier is presented, and finally there is an extrapolation to a large scale system

  9. The Elements and Principles of Design: A Baseline Study

    Science.gov (United States)

    Adams, Erin

    2013-01-01

    Critical to the discipline, both professionally and academically, are the fundamentals of interior design. These fundamentals include the elements and principles of interior design: the commonly accepted tools and vocabulary used to create and communicate successful interior environments. Research indicates a lack of consistency in both the…

  10. Non-Flutter Design Principle for long Span Bridges

    DEFF Research Database (Denmark)

    Johansson, Jens; Andersen, Michael Styrk; Starch Øvre, Michele

    velocity for a thin airfoil shows an asymptotical behavior. In traditional bridge design the torsional-to-vertical frequency ratio is increased to obtain higher flutter wind velocities. In the present study, we investigate, what we will label the non-flutter design principle, in which the torsional...

  11. Principle design of an energy efficient transfemoral prosthesis.

    NARCIS (Netherlands)

    Veltink, P.H.; Ünal, Ramazan; Eberle, W.; Hekman, Edsko E.G.; Carloni, Raffaella; Koopman, Hubertus F.J.M.; Stramigioli, Stefano

    2009-01-01

    In the pursuit of realizing an energy efficient transfemoral prosthetic, in this paper we present a preliminary study on a principle design. In particular, the design is based on the idea that the efficiency of the system can be realized by energetically coupling the knee and the ankle joints. In

  12. Design Principles of Next-Generation Digital Gaming for Education.

    Science.gov (United States)

    Squire, Kurt; Jenkins, Henry; Holland, Walter; Miller, Heather; O'Driscoll, Alice; Tan, Katie Philip; Todd, Katie.

    2003-01-01

    Discusses the rapid growth of digital games, describes research at MIT that is exploring the potential of digital games for supporting learning, and offers hypotheses about the design of next-generation educational video and computer games. Highlights include simulations and games; and design principles, including context and using information to…

  13. Designing User-Computer Dialogues: Basic Principles and Guidelines.

    Science.gov (United States)

    Harrell, Thomas H.

    This discussion of the design of computerized psychological assessment or testing instruments stresses the importance of the well-designed computer-user interface. The principles underlying the three main functional elements of computer-user dialogue--data entry, data display, and sequential control--are discussed, and basic guidelines derived…

  14. Engineering Design of an Adaptive Leg Prosthesis Using Biological Principles

    DEFF Research Database (Denmark)

    Lenau, Torben Anker; Dentel, Andy; Invarsdottir, Thorunn

    2010-01-01

    The biomimetic design process is explored through a design case: An adaptive leg prosthesis. The aim is to investigate if the biomimetic design process can be carried out with a minimum of biological knowledge and without using advanced design methods. In the design case biomimetic design was suc...... was successfully carried out using library search resulting in 14 biological analogies for the design problem 'shape adaption'. It is proposed that search results are handled using special cards describing the biological phenomena and the functional principles....

  15. Robust design principles for reducing variation in functional performance

    DEFF Research Database (Denmark)

    Christensen, Martin Ebro; Howard, Thomas J.

    2016-01-01

    This paper identifies, describes and classifies a comprehensive collection of variation reduction principles (VRP) that can be used to increase the robustness of a product and reduce its variation in functional performance. Performance variation has a negative effect on the reliability and percei......This paper identifies, describes and classifies a comprehensive collection of variation reduction principles (VRP) that can be used to increase the robustness of a product and reduce its variation in functional performance. Performance variation has a negative effect on the reliability...... and perceived quality of a product and efforts should be made to minimise it. The design principles are identified by a systematic decomposition of the Taguchi Transfer Function in combination with the use of existing literature and the authors’ experience. The paper presents 15 principles and describes...... their advantages and disadvantages along with example cases. Subsequently, the principles are classified based on their applicability in the various development and production stages. The VRP are to be added to existing robust design methodologies, helping the designer to think beyond robust design tool and method...

  16. Intelligent computer systems in engineering design principles and applications

    CERN Document Server

    Sunnersjo, Staffan

    2016-01-01

    This introductory book discusses how to plan and build useful, reliable, maintainable and cost efficient computer systems for automated engineering design. The book takes a user perspective and seeks to bridge the gap between texts on principles of computer science and the user manuals for commercial design automation software. The approach taken is top-down, following the path from definition of the design task and clarification of the relevant design knowledge to the development of an operational system well adapted for its purpose. This introductory text for the practicing engineer working in industry covers most vital aspects of planning such a system. Experiences from applications of automated design systems in practice are reviewed based on a large number of real, industrial cases. The principles behind the most popular methods in design automation are presented with sufficient rigour to give the user confidence in applying them on real industrial problems. This book is also suited for a half semester c...

  17. Patterns, principles, and practices of domain-driven design

    CERN Document Server

    Millett, Scott

    2015-01-01

    Methods for managing complex software construction following the practices, principles and patterns of Domain-Driven Design with code examples in C# This book presents the philosophy of Domain-Driven Design (DDD) in a down-to-earth and practical manner for experienced developers building applications for complex domains. A focus is placed on the principles and practices of decomposing a complex problem space as well as the implementation patterns and best practices for shaping a maintainable solution space. You will learn how to build effective domain models through the use of tactical pat

  18. Design criteria and principles for criticality detection and alarm systems

    International Nuclear Information System (INIS)

    Delafield, H.J.; Clifton, J.J.

    1984-10-01

    The report gives design principles and criteria for criticality detection and alarm systems based on earlier work and revised in the light of more recent experience. In particular, account is taken of the developments which have taken place in the field of radiation detection and in the understanding of the different types of criticality excursion. General guidance is given on the principles to apply in deciding upon the need for a criticality system. The characteristics of a criticality incident are described in terms of the minimum incident of concern, and the radiation field. Criteria for the threshold of detection of a criticality incident are then derived and the methods of detection considered. The selection and siting of criticality detectors is discussed, and design principles are given for alarm systems. Finally, testing and post-alarm procedures are outlined, followed by a summary of the principal recommendations. The supporting Appendices include a discussion of reliability and a summary of radiation detector characteristics. (author)

  19. Design principles and developmental mechanisms underlying retinal mosaics.

    Science.gov (United States)

    Reese, Benjamin E; Keeley, Patrick W

    2015-08-01

    Most structures within the central nervous system (CNS) are composed of different types of neuron that vary in both number and morphology, but relatively little is known about the interplay between these two features, i.e. about the population dynamics of a given cell type. How such arrays of neurons are distributed within a structure, and how they differentiate their dendrites relative to each other, are issues that have recently drawn attention in the invertebrate nervous system, where the genetic and molecular underpinnings of these organizing principles are being revealed in exquisite detail. The retina is one of the few locations where these principles have been extensively studied in the vertebrate CNS, indeed, where the design principles of 'mosaic regularity' and 'uniformity of coverage' were first explicitly defined, quantified, and related to each other. Recent studies have revealed a number of genes that influence the formation of these histotypical features in the retina, including homologues of those invertebrate genes, although close inspection reveals that they do not always mediate comparable developmental processes nor elucidate fundamental design principles. The present review considers just how pervasive these features of 'mosaic regularity' and 'uniform dendritic coverage' are within the mammalian retina, discussing the means by which such features can be assessed in the mature and developing nervous system and examining the limitations associated with those assessments. We then address the extent to which these two design principles co-exist within different populations of neurons, and how they are achieved during development. Finally, we consider the neural phenotypes obtained in mutant nervous systems, to address whether a prospective gene of interest underlies those very design principles. © 2014 The Authors. Biological Reviews © 2014 Cambridge Philosophical Society.

  20. Elements and Principles of Design Posters. Teacher's Guide.

    Science.gov (United States)

    1996

    This book accompanies a poster series and allows the teacher to pre-plan a lesson or activity for students with the objectives shown for each element or principle of design to be presented. Along with a black-and-white reproduction of each poster, major concepts are discussed. Suggested student activities relating to a particular element or…

  1. Implementation of the non-flutter design principle

    DEFF Research Database (Denmark)

    Andersen, Michael Styrk; Sahin, Emrah; Laustsen, Benjamin

    2014-01-01

    The non-flutter design principle is introduced. Aerodynamically stable section model tests performed by three different research groups indicate, that flutter might be avoided if the torsional-to-vertical frequency ratio is kept below 1. A case study of a suspension bridge spanning 3:7 km...

  2. Design Principles for Cell Phone Learning in EFL

    Science.gov (United States)

    Wang, Feihong

    2010-01-01

    Cell phone learning (C-learning), as an instructional approach, has been gaining more and more attention in the field of teaching English as a foreign language (EFL) in the last 10 years. While studies have proved C-learning an effective instructional approach in research settings, a review of literature indicates the lack of design principles to…

  3. Design principle and structure of the ANI data centre

    International Nuclear Information System (INIS)

    Akopov, N.Z.; Arutyunyan, S.Kh.; Chilingaryan, A.A.; Galfayan, S.Kh.; Matevosyan, V.Kh.; Zazyan, M.Z.

    1985-01-01

    The design principles and structure of applied statistical programms used for processing the data from the ANI experiments are described. Nonparametric algorithms provide development of high-efficient method for simultaneous analysis of computerized and experimental data, from cosmic ray experiments. Relation data base for unified data storage, protection, renewing and erasuring as well as for fast and convenient information retrieval is considered

  4. Design Principles for Improving the Process of Publishing Open data

    NARCIS (Netherlands)

    Zuiderwijk, A.M.G.; Janssen, M.F.W.H.A.; Choenni, R.; Meijer, R.F.

    2014-01-01

    · Purpose: Governments create large amounts of data. However, the publication of open data is often cumbersome and there are no standard procedures and processes for opening data. This blocks the easy publication of government data. The purpose of this paper is to derive design principles for

  5. Authentic tasks in higher education: Studying design principles for assessment

    NARCIS (Netherlands)

    van Keulen, H.; van den Berg, I.; Ramaekers, S.

    2006-01-01

    Students may benefit significantly from learning through authentic tasks. But how do we assess their learning outcomes, taking into account the specific characteristics of authentic tasks? In the second presentation of this symposium on design principles for authentic tasks we present and discuss

  6. Web Interface Design Principles for Adults' Self-Directed Learning

    Science.gov (United States)

    Firat, Mehmet; Sakar, A. Nurhan; Kabakci Yurdakul, Isil

    2016-01-01

    One of the most important features which e-learning tools and environments must possess within the scope of lifelong learning is self-directed learning, which can be considered as a form of self-learning. The aim of this study was to determine, based on the views and recommendations of experts, interface design principles for the development of…

  7. Students' guide to program design

    CERN Document Server

    Robertson, Lesley Anne

    1992-01-01

    Students' Guide to Program Design is a textbook on program design. This textbook approaches program design by using structures programming techniques and pseudocode to develop a solution algorithm. Divided into 10 chapters, the book begins with a basic explanation of structured programming techniques, top-down development, and modular design. This discussion is followed by detailed concepts of the syntax of pseudocode; methods of defining the problem; the application of basic control structures in the development of the solution algorithm; desk checking techniques; hierarchy charts; and module

  8. Computers as components principles of embedded computing system design

    CERN Document Server

    Wolf, Marilyn

    2012-01-01

    Computers as Components: Principles of Embedded Computing System Design, 3e, presents essential knowledge on embedded systems technology and techniques. Updated for today's embedded systems design methods, this edition features new examples including digital signal processing, multimedia, and cyber-physical systems. Author Marilyn Wolf covers the latest processors from Texas Instruments, ARM, and Microchip Technology plus software, operating systems, networks, consumer devices, and more. Like the previous editions, this textbook: Uses real processors to demonstrate both technology and tec

  9. Applying multimedia design principles enhances learning in medical education.

    Science.gov (United States)

    Issa, Nabil; Schuller, Mary; Santacaterina, Susan; Shapiro, Michael; Wang, Edward; Mayer, Richard E; DaRosa, Debra A

    2011-08-01

    The Association of American Medical Colleges' Institute for Improving Medical Education's report entitled 'Effective Use of Educational Technology' called on researchers to study the effectiveness of multimedia design principles. These principles were empirically shown to result in superior learning when used with college students in laboratory studies, but have not been studied with undergraduate medical students as participants. A pre-test/post-test control group design was used, in which the traditional-learning group received a lecture on shock using traditionally designed slides and the modified-design group received the same lecture using slides modified in accord with Mayer's principles of multimedia design. Participants included Year 3 medical students at a private, midwestern medical school progressing through their surgery clerkship during the academic year 2009-2010. The medical school divides students into four groups; each group attends the surgery clerkship during one of the four quarters of the academic year. Students in the second and third quarters served as the modified-design group (n=91) and students in the fourth-quarter clerkship served as the traditional-design group (n=39). Both student cohorts had similar levels of pre-lecture knowledge. Both groups showed significant improvements in retention (paffect transfer of learning. Further research on applying the principles of multimedia design to medical education is needed to verify the impact it has on the long-term learning of medical students, as well as its impact on other forms of multimedia instructional programmes used in the education of medical students. © Blackwell Publishing Ltd 2011.

  10. Chemical Frustration. A Design Principle for the Discovery of New Complex Alloy and Intermetallic Phases, Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Fredrickson, Daniel C [Univ. of Wisconsin, Madison, WI (United States)

    2015-06-23

    Final technical report for "Chemical Frustration: A Design Principle for the Discovery of New Complex Alloy and Intermetallic Phases" funded by the Office of Science through the Materials Chemistry Program of the Office of Basic Energy Sciences.

  11. Experimental application of design principles in corrosion research

    International Nuclear Information System (INIS)

    Smyrl, W.H.; Pohlman, S.L.

    1977-01-01

    Experimental design criteria for corrosion investigations are based on established principles for systems that have uniform, or nearly uniform, corrosive attack. Scale-up or scale-down may be accomplished by proper use of dimensionless groups that measure the relative importance of interfacial kinetics, solution conductivity, and mass transfer. These principles have been applied to different fields of corrosion which include materials selection testing and protection; and to a specific corrosion problem involving attack of a substrate through holes in a protective overplate

  12. Applying principles of Design For Assembly to ITER maintenance operations

    International Nuclear Information System (INIS)

    Heemskerk, Cock; de Baar, Marco; Elzendoorn, Ben; Koning, Jarich; Verhoeven, Toon; Vreede, Fred de

    2009-01-01

    In ITER, maintenance operations in the vessel and in the Hot Cell will be largely done by Remote Handling (RH). Remotely performed maintenance actions tend to be more time-costly than actions performed by direct human access. With a human operator in the control loop and adequate situational feedback, a two-armed master slave manipulator system can mimic direct access with dexterous manipulation, tactile feedback and vision. But even then, turnaround times are still very high. Adapting the design for simplified maintenance operations can yield significant time savings. One of the methods known to produce a simpler, more robust design, which is also better suited for handling with robots, is Design For Assembly (DFA). This paper discusses whether and how the principles of DFA can be applied to simplify maintenance operations for ITER. While DFA is normally used with series-production and ITER is a unique product, it is possible to apply the principles of DFA to ITER maintenance operations. Furthermore, DFA's principles can be applied at different abstraction levels. Combining principles of DFA with Virtual Reality leads to new insights and provides additional value.

  13. Design and evaluation of an integrated safeguards system: principles

    International Nuclear Information System (INIS)

    Markin, J.T.; Coulter, C.A.; Gutmacher, R.G.; Whitty, W.J.

    1984-07-01

    An integrated safeguards system is defined as a collection of safeguards activities in which system components are coordinated to meet safeguards objectives efficiently within constraints imposed by safeguards resources, facility operations, potential adversaries, and regulatory requirements. This paper describes principles for designing and evaluating an integrated safeguards system that consists of four parts: (1) a problem definition phase that specifies resources and constraints composing the problem boundary values; (2) a system analysis/synthesis phase that describes how to select and integrate safeguards activities for efficient attainment of system objectives; (3) a system evaluation/optimization phase that defines measures of safeguards performance and develops methods for evaluating them; and (4) a decision-making phase that develops principles for selecting admissible designs and preference-ordering designs. 6 references, 4 figures, 5 tables

  14. Design and evaluation of an integrated safeguards system: principles

    International Nuclear Information System (INIS)

    Markin, J.T.; Coulter, C.A.; Gutmacher, R.G.; Whitty, W.J.

    1984-01-01

    An integrated safeguards system is defined as a collection of safeguards activities in which system components are coordinated to meet safeguards objectives efficiently within constraints imposed by safeguards resources, facility operations, potential adversaries, and regulatory requirements. This paper describes principles for designing and evaluating an integrated safeguards system that consists of four parts: a problem definition phase that specifies resources and constraints composing the problem boundary values, a system analysis/synthesis phase that describes how to select and integrate safeguards activities for efficient attainment of system objectives, a system evaluation/optimization phase that defines measures of safeguards performance and develops methods for evaluating them, and a decision-making phase that develops principles for selecting admissible designs and preference-ordering designs

  15. Mechanical design of an electronic control unit using axiomatic principles

    Directory of Open Access Journals (Sweden)

    Cazacu Vlad

    2017-01-01

    Full Text Available If the engine of the car can be considered as the heart, then the E.C.U’s represents the brain of the car. Electronic control units (E.C.U’s are electronic devices which control the way different components of a car (engine, windows, airbags, etc. react in some situations (overheating, button pressed by a passenger, crash, etc.. Axiomatic design is a set of principles that theorizes the act of conceiving a new project. Based on two axiom this method comes into designers help, giving them the option to reach in a short period of time a fully functional and compliant product without supporting the design of the product on chance, past experiences or “try and fail” principle.

  16. Theory-generating practice. Proposing a principle for learning design

    DEFF Research Database (Denmark)

    Buhl, Mie

    2016-01-01

    This contribution proposes a principle for learning design – Theory-Generating Practice (TGP) – as an alternative to the way university courses are traditionally taught and structured, with a series of theoretical lectures isolated from practical experience and concluding with an exam or a project...... building, and takes tacit knowledge into account. The article introduces TGP, contextualizes it to a Danish tradition of didactics, and discusses it in relation to contemporary conceptual currents of didactic design and learning design. This is followed by a theoretical framing of TGP. Finally, three...

  17. Babinet principle applied to the design of metasurfaces and metamaterials.

    Science.gov (United States)

    Falcone, F; Lopetegi, T; Laso, M A G; Baena, J D; Bonache, J; Beruete, M; Marqués, R; Martín, F; Sorolla, M

    2004-11-05

    The electromagnetic theory of diffraction and the Babinet principle are applied to the design of artificial metasurfaces and metamaterials. A new particle, the complementary split rings resonator, is proposed for the design of metasurfaces with high frequency selectivity and planar metamaterials with a negative dielectric permittivity. Applications in the fields of frequency selective surfaces and polarizers, as well as in microwave antennas and filter design, can be envisaged. The tunability of all these devices by an applied dc voltage is also achievable if these particles are etched on the appropriate substrate.

  18. Infusing Adult Education Principles Into a Health Insurance Literacy Program.

    Science.gov (United States)

    Brown, Virginia

    2018-03-01

    Health insurance literacy is an emerging concept in the health education and health promotion field. The passage of the Affordable Care Act highlighted the link between health insurance and health outcomes. However, the law does not specifically address how the public should be educated on choosing an appropriate health insurance plan. Research shows adults, regardless of previous health insurance status, are likely confused and uncertain about their selection. The University of Maryland Extension developed and created health insurance Smart Choice Health Insurance™ to reduce confusion and increase confidence and capability to make this decision. Andragogy, an adult learning theory, was used to guide the development of the program and help ensure best practices are used to achieve desired outcomes. Using the six principles of andragogy, the team incorporated reality-based case studies, allowed adults time to practice, and emphasized choice making and many other elements to create an atmosphere conducive to adult learning. Results from Smart Choice indicate the program is successful in reducing confusion and increasing confidence. Furthermore, feedback from participants and trained educators indicates that adults were engaged in the program and found the materials useful. Based on program success, creation of new health insurance literacy programs grounded in adult education principles is under way.

  19. Design principles of a web interface for monitoring tools

    International Nuclear Information System (INIS)

    Aiftimiei, C; Pra, S D; Fantinel, S; Andreozzi, S; Fattibene, E; Misurelli, G; Cuscela, G; Donvito, G; Dudhalkar, V; Maggi, G; Pierro, A

    2008-01-01

    A monitoring tool of a complex Grid system can gather a huge amount of information that have to be presented to the users in the most comprehensive way. Moreover different types of consumers could be interested in inspecting and analyzing different subsets of data. The main goal in designing a Web interface for the presentation of monitoring information is to organize the huge amount of data in a simple, user-friendly and usable structure. One more problem is to consider different approaches, skills and interests that all the possible categories of users have in looking for the desired information. Starting from the Information Architecture guidelines for the Web, it is possible to design Web interfaces towards a closer user experience and to deal with an advanced user interaction through the implementation of many Web standard technologies. In this paper, we will present a number of principles for the design of Web interface for monitoring tools that provide a wider, richer range of possibilities for what concerns the user interaction. These principles are based on an extensive review of the current literature in Web design and on the experience with the development of the GridICE monitoring tool. The described principles can drive the evolution of the Web interface of Grid monitoring tools

  20. Digital sonar design in underwater acoustics principles and applications

    CERN Document Server

    Li, Qihu

    2012-01-01

    "Digital Sonar Design in Underwater Acoustics Principles and Applications" provides comprehensive and up-to-date coverage of research on sonar design, including the basic theory and techniques of digital signal processing, basic concept of information theory, ocean acoustics, underwater acoustic signal propagation theory, and underwater signal processing theory. This book discusses the general design procedure and approaches to implementation, the design method, system simulation theory and techniques, sonar tests in the laboratory, lake and sea, and practical validation criteria and methods for digital sonar design. It is intended for researchers in the fields of underwater signal processing and sonar design, and also for navy officers and ocean explorers. Qihu Li is a professor at the Institute of Acoustics, Chinese Academy of Sciences, and an academician of the Chinese Academy of Sciences.

  1. Zero Energy Buildings – Design Principles and Built Examples

    DEFF Research Database (Denmark)

    Designing a zero energy building is a complicated task, and in order to achieve good results it is necessary to include knowledge from a range of sources. Therefore, cooperation is required between different professions and between generalists and specialists from the very beginning of the process...... knowledge must be acquired, depending on the project in question. Through a cross-disciplinary approach to architecture and building design, and based on an integrated design process, this publication will: • introduce a number of design strategies and technologies which are particularly important...... for the development of zero energy houses. These strategies and technologies are illustrated through simple design principles and built examples • identify technical and architectural potentials and challenges related to design strategies of crucial importance to the development of zero energy houses • identify...

  2. Client Mobile Software Design Principles for Mobile Learning Systems

    Directory of Open Access Journals (Sweden)

    Qing Tan

    2009-01-01

    Full Text Available In a client-server mobile learning system, client mobile software must run on the mobile phone to acquire, package, and send student’s interaction data via the mobile communications network to the connected mobile application server. The server will receive and process the client data in order to offer appropriate content and learning activities. To develop the mobile learning systems there are a number of very important issues that must be addressed. Mobile phones have scarce computing resources. They consist of heterogeneous devices and use various mobile operating systems, they have limitations with their user/device interaction capabilities, high data communications cost, and must provide for device mobility and portability. In this paper we propose five principles for designing Client mobile learning software. A location-based adaptive mobile learning system is presented as a proof of concept to demonstrate the applicability of these design principles.

  3. Design principles for achieving integrated healthcare information systems.

    Science.gov (United States)

    Jensen, Tina Blegind

    2013-03-01

    Achieving integrated healthcare information systems has become a common goal for many countries in their pursuit of obtaining coordinated and comprehensive healthcare services. This article focuses on how a small local project termed 'Standardized pull of patient data' expanded and is now used on a large scale providing a majority of hospitals, general practitioners and citizens across Denmark with the possibility of accessing healthcare data from different electronic patient record systems and other systems. I build on design theory for information infrastructures, as presented by Hanseth and Lyytinen, to examine the design principles that facilitated this smallscale project to expand and become widespread. As a result of my findings, I outline three lessons learned that emphasize: (i) principles of flexibility, (ii) expansion from the installed base through modular strategies and (iii) identification of key healthcare actors to provide them with immediate benefits.

  4. Using Mathematical Modeling and Set-Based Design Principles to Recommend an Existing CVL Design

    Science.gov (United States)

    2017-09-01

    MATHEMATICAL MODELING AND SET-BASED DESIGN PRINCIPLES TO RECOMMEND AN EXISTING CVL DESIGN by William H. Ehlies September 2017 Thesis Advisor...Office of Management and Budget, Paperwork Reduction Project (0704-0188) Washington, DC 20503. 1. AGENCY USE ONLY (Leave blank) 2. REPORT DATE...September 2017 3. REPORT TYPE AND DATES COVERED Master’s thesis 4. TITLE AND SUBTITLE USING MATHEMATICAL MODELING AND SET-BASED DESIGN PRINCIPLES

  5. Program Theory for Participatory Design

    DEFF Research Database (Denmark)

    Bossen, Claus; Dindler, Christian; Iversen, Ole Sejer

    2018-01-01

    How does participatory design work and what are the links between investments in terms of time, people and skills, the processes and the resulting effects? This paper explores program theory as a way for Participatory Design (PD) to investigate and evaluate these issues. Program theory comes out...

  6. Design for Natural Breast Augmentation: The ICE Principle.

    Science.gov (United States)

    Mallucci, Patrick; Branford, Olivier Alexandre

    2016-06-01

    The authors' published studies have helped define breast beauty in outlining key parameters that contribute to breast attractiveness. The "ICE" principle puts design into practice. It is a simplified formula for inframammary fold incision planning as part of the process for determining implant selection and placement to reproduce the 45:55 ratio previously described as fundamental to natural breast appearance. The formula is as follows: implant dimensions (I) - capacity of the breast (C) = excess tissue required (E). The aim of this study was to test the accuracy of the ICE principle for producing consistent natural beautiful results in breast augmentation. A prospective analysis of 50 consecutive women undergoing primary breast augmentation by means of an inframammary fold incision with anatomical or round implants was performed. The ICE principle was applied to all cases to determine implant selection, placement, and incision position. Changes in parameters between preoperative and postoperative digital clinical photographs were analyzed. The mean upper pole-to-lower pole ratio changed from 52:48 preoperatively to 45:55 postoperatively (p principle for surgical planning in breast augmentation that attractive natural breasts may be achieved consistently and with precision. Therapeutic, IV.

  7. Power electronics basics operating principles, design, formulas, and applications

    CERN Document Server

    Rozanov, Yuriy; Chaplygin, Evgeny; Voronin, Pavel

    2015-01-01

    Power Electronics Basics: Operating Principles, Design, Formulas, and Applications provides fundamental knowledge for the analysis and design of modern power electronic devices. This concise and user-friendly resource:Explains the basic concepts and most important terms of power electronicsDescribes the power assemblies, control, and passive components of semiconductor power switchesCovers the control of power electronic devices, from mathematical modeling to the analysis of the electrical processesAddresses pulse-width modulation, power quality control, and multilevel, modular, and multicell

  8. Industrial and process furnaces principles, design and operation

    CERN Document Server

    Jenkins, Barrie

    2014-01-01

    Furnaces sit at the core of all branches of manufacture and industry, so it is vital that these are designed and operated safely and effi-ciently. This reference provides all of the furnace theory needed to ensure that this can be executed successfully on an industrial scale. Industrial and Process Furnaces: Principles, 2nd Edition provides comprehensive coverage of all aspects of furnace operation and design, including topics essential for process engineers and operators to better understand furnaces. This includes: the combustion process and its control, furnace fuels, efficiency,

  9. AGROECOLOGY: PRINCIPLES AND STRATEGIES FOR THE DESIGN OF SUSTAINABLE AGROECOSYSTEMS

    Directory of Open Access Journals (Sweden)

    João Carlos Canuto

    2017-04-01

    Full Text Available The theme of this paper is the debate on principles and strategies for designing sustainable agricultural systems. The paper builds on a broad approach to principles, moving to the more specific approach to strategies and finalizing with a micro-scale perspective on the practice of drawings and the consequences of each possible option. The objective is first of all to put to the debate the dialectic between conceptual plurality and unity in Agroecology. The problem in focus is to situate more clearly what are sustainable agroecosystems and, as a consequence, how to connect principles and strategies to make them viable. Regarding the theoretical reference, we use the classic authors of Agroecology and some critical articles on the conceptual question. The methodology that gives foundation to the approach is based on the author's theoretical and practical experience, with a qualitative, subjective and intuitive character. The results are only the presentation of ideas in order to contribute to the conceptual debate now in vogue and also to glimpse, on a smaller scale, the practical issue of sustainable agroecosystems designs.

  10. Semiconductor-inspired design principles for superconducting quantum computing.

    Science.gov (United States)

    Shim, Yun-Pil; Tahan, Charles

    2016-03-17

    Superconducting circuits offer tremendous design flexibility in the quantum regime culminating most recently in the demonstration of few qubit systems supposedly approaching the threshold for fault-tolerant quantum information processing. Competition in the solid-state comes from semiconductor qubits, where nature has bestowed some very useful properties which can be utilized for spin qubit-based quantum computing. Here we begin to explore how selective design principles deduced from spin-based systems could be used to advance superconducting qubit science. We take an initial step along this path proposing an encoded qubit approach realizable with state-of-the-art tunable Josephson junction qubits. Our results show that this design philosophy holds promise, enables microwave-free control, and offers a pathway to future qubit designs with new capabilities such as with higher fidelity or, perhaps, operation at higher temperature. The approach is also especially suited to qubits on the basis of variable super-semi junctions.

  11. Designing the Electronic Classroom: Applying Learning Theory and Ergonomic Design Principles.

    Science.gov (United States)

    Emmons, Mark; Wilkinson, Frances C.

    2001-01-01

    Applies learning theory and ergonomic principles to the design of effective learning environments for library instruction. Discusses features of electronic classroom ergonomics, including the ergonomics of physical space, environmental factors, and workstations; and includes classroom layouts. (Author/LRW)

  12. Parallelization for first principles electronic state calculation program

    International Nuclear Information System (INIS)

    Watanabe, Hiroshi; Oguchi, Tamio.

    1997-03-01

    In this report we study the parallelization for First principles electronic state calculation program. The target machines are NEC SX-4 for shared memory type parallelization and FUJITSU VPP300 for distributed memory type parallelization. The features of each parallel machine are surveyed, and the parallelization methods suitable for each are proposed. It is shown that 1.60 times acceleration is achieved with 2 CPU parallelization by SX-4 and 4.97 times acceleration is achieved with 12 PE parallelization by VPP 300. (author)

  13. Design principles and operating principles: the yin and yang of optimal functioning.

    Science.gov (United States)

    Voit, Eberhard O

    2003-03-01

    Metabolic engineering has as a goal the improvement of yield of desired products from microorganisms and cell lines. This goal has traditionally been approached with experimental biotechnological methods, but it is becoming increasingly popular to precede the experimental phase by a mathematical modeling step that allows objective pre-screening of possible improvement strategies. The models are either linear and represent the stoichiometry and flux distribution in pathways or they are non-linear and account for the full kinetic behavior of the pathway, which is often significantly effected by regulatory signals. Linear flux analysis is simpler and requires less input information than a full kinetic analysis, and the question arises whether the consideration of non-linearities is really necessary for devising optimal strategies for yield improvements. The article analyzes this question with a generic, representative pathway. It shows that flux split ratios, which are the key criterion for linear flux analysis, are essentially sufficient for unregulated, but not for regulated branch points. The interrelationships between regulatory design on one hand and optimal patterns of operation on the other suggest the investigation of operating principles that complement design principles, like a user's manual complements the hardwiring of electronic equipment.

  14. In search of design principles for developing digital learning & performance support for a student design task

    NARCIS (Netherlands)

    Bollen, Lars; van der Meij, Hans; Leemkuil, Hendrik H.; McKenney, Susan

    2015-01-01

    A digital learning and performance support environment for university student design tasks was developed. This paper describes on the design rationale, process, and the usage results to arrive at a core set of design principles for the construction of such an environment. We present a collection of

  15. In search of design principles for developing digital learning & performance support for a student design task

    NARCIS (Netherlands)

    Bollen, Lars; Van der Meij, Hans; Leemkuil, Henny; McKenney, Susan

    2016-01-01

    A digital learning and performance support environment for university student design tasks was developed. This paper describes on the design rationale, process, and the usage results to arrive at a core set of design principles for the construction of such an environment. We present a collection of

  16. The design of the MAD Design Program

    International Nuclear Information System (INIS)

    Niederer, J.

    1992-01-01

    The study of long term stability in particle accelerators has long been served by a group of widely circulated computer programs. The progress in these programs has mirrored the growth and versatility in accelerator size, complexity, and purpose, as well as evolving technologies in computing software and hardware. A number of large accelerator projects during the last decade were designed with the aid of physics programs either written for, or tailored for the project at hand, each invariably benefiting from contributions of previous workers. This paper outlines the recent history of of expample of an accelerator lattice model tool kit, the Methodical Accelerator Design (MAD) Program, which has tried to knit together this collective wisdom of the accelerator community, The ideas behind the software design of the program itself are traced here; the accelerator physics contents and origins are thoroughly documented elsewhere. These informal notes have a Brookhaven flavor, in part because of early BNL efforts to generalize the ways that technical problems are organized and presented to computers. Some recent BNL applications not covered in the extensive CERN documentation are also included

  17. Proof of principle for epitope-focused vaccine design

    Science.gov (United States)

    Correia, Bruno E.; Bates, John T.; Loomis, Rebecca J.; Baneyx, Gretchen; Carrico, Chris; Jardine, Joseph G.; Rupert, Peter; Correnti, Colin; Kalyuzhniy, Oleksandr; Vittal, Vinayak; Connell, Mary J.; Stevens, Eric; Schroeter, Alexandria; Chen, Man; MacPherson, Skye; Serra, Andreia M.; Adachi, Yumiko; Holmes, Margaret A.; Li, Yuxing; Klevit, Rachel E.; Graham, Barney S.; Wyatt, Richard T.; Baker, David; Strong, Roland K.; Crowe, James E.; Johnson, Philip R.; Schief, William R.

    2014-03-01

    Vaccines prevent infectious disease largely by inducing protective neutralizing antibodies against vulnerable epitopes. Several major pathogens have resisted traditional vaccine development, although vulnerable epitopes targeted by neutralizing antibodies have been identified for several such cases. Hence, new vaccine design methods to induce epitope-specific neutralizing antibodies are needed. Here we show, with a neutralization epitope from respiratory syncytial virus, that computational protein design can generate small, thermally and conformationally stable protein scaffolds that accurately mimic the viral epitope structure and induce potent neutralizing antibodies. These scaffolds represent promising leads for the research and development of a human respiratory syncytial virus vaccine needed to protect infants, young children and the elderly. More generally, the results provide proof of principle for epitope-focused and scaffold-based vaccine design, and encourage the evaluation and further development of these strategies for a variety of other vaccine targets, including antigenically highly variable pathogens such as human immunodeficiency virus and influenza.

  18. Zero Energy Buildings – Design Principles and Built Examples

    DEFF Research Database (Denmark)

    Bejder, Anne Kirkegaard; Knudstrup, Mary-Ann; Jensen, Rasmus Lund

    Designing a zero energy building is a complicated task, and in order to achieve good results it is necessary to include knowledge from a range of sources. Therefore, cooperation is required between different professions and between generalists and specialists from the very beginning of the process...... for the development of zero energy houses. These strategies and technologies are illustrated through simple design principles and built examples • identify technical and architectural potentials and challenges related to design strategies of crucial importance to the development of zero energy houses • identify...... technical and architectural potentials and challenges related to the application of new technologies • make visible engineering and architectural issues and create greater transparency, providing a point of departure for cross-disciplinary cooperation....

  19. Principles of human joint replacement design and clinical application

    CERN Document Server

    Buechel, Frederick F

    2015-01-01

    This book is written for the users and designers of joint replacements. In its second extended edition it conveys to the reader the knowledge accumulated by the authors during their forty year effort on the development of replacement devices for the lower limb for the purpose of aiding the reader in their design and evaluation of joint replacement devices. The early chapters describe the engineering, scientific and medical principles needed for replacement joint evaluation. One must understand the nature and performance of the materials involved and their characteristics in vivo, i.e. the response of the body to implant materials. It is also essential to understand the response of the implants to applied loading and motion, particularly in the hostile physiological environment. A chapter describes the design methodology now required for joint replacement in the USA and EU countries. The remaining chapters provide a history of joint replacement, an evaluation of earlier and current devices and sample case hist...

  20. Principles of Human Joint Replacement Design and Clinical Application

    CERN Document Server

    Buechel, Frederick F

    2012-01-01

    Drs. Buechel, an orthopaedic surgeon, and Pappas, a professor of Mechanical Engineering, are the designers of several successful joint replacement systems. The most well-known of these is the pioneering LCS knee replacement. They have written this book for the users and designers of joint replacements. It is an attempt to convey to the reader the knowledge accumulated by the authors during their thirty five year effort on the development of replacement devices for the lower limb for the purpose of aiding the reader in their design and evaluation of joint replacement devices. The early chapters describe the engineering, scientific and medical principles needed for replacement joint evaluation. One must understand the nature and performance of the materials involved and their characteristics in vivo, i.e. the response of the body to implant materials. It is also essential to understand the response of the implants to applied loading and motion, particularly in the hostile physiological environment. A chapter de...

  1. Autonomous Reactivity Control (ARC) — Principles, geometry and design process

    Energy Technology Data Exchange (ETDEWEB)

    Qvist, Staffan A., E-mail: staffan.qvist@physics.uu.se [Department of Physics and Astronomy, Uppsala University, Uppsala (Sweden); Department of Nuclear Engineering, University of California Berkeley (United States); Hellesen, Carl [Department of Physics and Astronomy, Uppsala University, Uppsala (Sweden); Thiele, Roman [Division of Reactor Technology, Royal Institute of Technology, Stockholm (Sweden); Dubberley, Allen E. [General Electric Advanced Reactor Systems Department (retired), Sunnyvale, CA (United States); Gradecka, Malwina; Greenspan, Ehud [Department of Nuclear Engineering, University of California Berkeley (United States)

    2016-10-15

    Highlights: • Here we define the principles of the operation and design of ARC systems. • ARC systems can provide inherent safety during and following unprotected transients. • A manufacturing and assembly method was developed and presented. - Abstract: The Autonomous Reactivity Control (ARC) system was developed to ensure inherent safety performance of Generation-IV reactors while having a minimal impact on reactor performance and economic viability. Here we present in detail the principles of how the ARC system operates, what materials should be used, what components make up the system and how they are interconnected. The relevant equations regarding how to design the system for a certain response are developed and defined, and the most important aspects determining the speed of actuation of the systems are analyzed. Thus, this study serves as the general reference material for all of the fundamental principles behind the ARC idea. Finally, we present a step-by-step guide to how a fast reactor fuel subassembly with an ARC system installed would be manufactured, using a full 3D-CAD model. For an ARC installation in a 1000 MWth sodium-cooled oxide-fueled fast reactor core, the system constitutes a relatively minor adjustment to a typical fuel assembly, increasing its total axial extent by ∼5–10% and the total primary coolant pressure drop by ∼1%. The main finding of this study is that it is possible to design, manufacture (using existing methods) and implement ARC systems in the fuel assemblies of fast reactor cores to provide inherent safety in all anticipated unprotected transients with only a modest increase in the length of the assembly and the pressure drop across the core.

  2. Reconfigurable manufacturing systems: Principles, design, and future trends

    Science.gov (United States)

    Koren, Yoram; Gu, Xi; Guo, Weihong

    2018-06-01

    Reconfigurable manufacturing systems (RMSs), which possess the advantages of both dedicated serial lines and flexible manufacturing systems, were introduced in the mid-1990s to address the challenges initiated by globalization. The principal goal of an RMS is to enhance the responsiveness of manufacturing systems to unforeseen changes in product demand. RMSs are costeffective because they boost productivity, and increase the lifetime of the manufacturing system. Because of the many streams in which a product may be produced on an RMS, maintaining product precision in an RMS is a challenge. But the experience with RMS in the last 20 years indicates that product quality can be definitely maintained by inserting in-line inspection stations. In this paper, we formulate the design and operational principles for RMSs, and provide a state-of-the-art review of the design and operations methodologies of RMSs according to these principles. Finally, we propose future research directions, and deliberate on how recent intelligent manufacturing technologies may advance the design and operations of RMSs.

  3. Using Green Chemistry and Engineering Principles to Design ...

    Science.gov (United States)

    The concepts of green chemistry and engineering (GC&E) have been promoted as an effective qualitative framework for developing more sustainable chemical syntheses, processes, and material management techniques. This has been demonstrated by many theoretical and practical cases. In addition, there are several approaches and frameworks focused on demonstrating that improvements were achieved through GC&E technologies. However, the application of these principles is not always straightforward. We propose using systematic frameworks and tools that help practitioners when deciding which principles can be applied, the levels of implementation, prospective of obtaining simultaneous improvements in all sustainability aspects, and ways to deal with multiobjective problems. Therefore, this contribution aims to provide a systematic combination of three different and complementary design tools for assisting designers in evaluating, developing, and improving chemical manufacturing and material management systems under GC&E perspectives. The WAR Algorithm, GREENSCOPE, and SustainPro were employed for this synergistic approach of incorporating sustainability at early stages of process development. In this demonstration, simulated ammonia production is used as a case study to illustrate this advancement. Results show how to identify process design areas for improvements, key factors, multi-criteria decision-making solutions, and optimal tradeoffs. Finally, conclusions were pre

  4. SYSTEMATIC PRINCIPLES AND METHODS OF SYMBOLIC APPROACHES IN URBAN DESIGN

    Directory of Open Access Journals (Sweden)

    BULAKH I. V

    2015-12-01

    Full Text Available Formulation of the problem. The low level of expression and personalization of mass architecture of the second half of the twentieth century connected with the spread of industrial technology and even to a greater extent with mechanistic traditionally functional relation to the average person as, abstract consumer architecture. The condition out of the critical situation is focusing on matters aesthetic, artistic understanding and harmonious image creation environment. The problem of increasing architectural and artistic level of architectural and urban planning solutions to overcome the monotony of planning and development, creating aesthetically expressive urban environment does not lose relevance over the past decades. Understanding and acceptance of enigma and dynamic development of cities encourage architects to find new design techniques that are able to provide in the future a reasonable possibility of forming artistic and aesthetic image of the modern city. Purpose. Define and systematize the principles of symbolization architectural and planning images; propose methods symbolism in the architectural planning of image of the urban environment. Conclusion based on analysis of the enhanced concept symbolizing the image of Architecture and Planning, the place, role and symbolization trends at all levels of the urban environment - planning, three-dimensional and improvement of urban areas; first identified the main stages and levels of symbolization (analohyzatsyya, schematization and alehoryzatsiya, their features and characteristics, formulated the basic principles of symbolization architectural and planning of image, namely the principles of communication between figurative analogies, transformation of subsequent circuits, switching allegorical groupings and metamorfizm ultimate goal – symbol birth .

  5. Integrating rock mechanics issues with repository design through design process principles and methodology

    International Nuclear Information System (INIS)

    Bieniawski, Z.T.

    1996-01-01

    A good designer needs not only knowledge for designing (technical know-how that is used to generate alternative design solutions) but also must have knowledge about designing (appropriate principles and systematic methodology to follow). Concepts such as open-quotes design for manufactureclose quotes or open-quotes concurrent engineeringclose quotes are widely used in the industry. In the field of rock engineering, only limited attention has been paid to the design process because design of structures in rock masses presents unique challenges to the designers as a result of the uncertainties inherent in characterization of geologic media. However, a stage has now been reached where we are be able to sufficiently characterize rock masses for engineering purposes and identify the rock mechanics issues involved but are still lacking engineering design principles and methodology to maximize our design performance. This paper discusses the principles and methodology of the engineering design process directed to integrating site characterization activities with design, construction and performance of an underground repository. Using the latest information from the Yucca Mountain Project on geology, rock mechanics and starter tunnel design, the current lack of integration is pointed out and it is shown how rock mechanics issues can be effectively interwoven with repository design through a systematic design process methodology leading to improved repository performance. In essence, the design process is seen as the use of design principles within an integrating design methodology, leading to innovative problem solving. In particular, a new concept of open-quotes Design for Constructibility and Performanceclose quotes is introduced. This is discussed with respect to ten rock mechanics issues identified for repository design and performance

  6. A case study analysis of the application of design for manufacture principles by industrial design students

    OpenAIRE

    Marshall, R; Page, T

    2016-01-01

    This paper describes a case study evaluation of a module that engages students on product and industrial design programmes with the principles of Design for Manufacturing (DFM). The primary element of the module is to expose students to the constraints of a full design to manufacture process. The module explores the design of a small polymer promotional item, together with the means of mass producing that item. This is done through the process of injection moulding and students design an inje...

  7. Design principles and algorithms for automated air traffic management

    Science.gov (United States)

    Erzberger, Heinz

    1995-01-01

    This paper presents design principles and algorithm for building a real time scheduler. The primary objective of the scheduler is to assign arrival aircraft to a favorable landing runway and schedule them to land at times that minimize delays. A further objective of the scheduler is to allocate delays between high altitude airspace far from the airport and low altitude airspace near the airport. A method of delay allocation is described that minimizes the average operating cost in the presence of errors in controlling aircraft to a specified landing time.

  8. Basic Principles of Industrial Electric Power Network Computer Aided Design and Engineering

    Directory of Open Access Journals (Sweden)

    M. I. Fursanov

    2012-01-01

    Full Text Available A conceptual model for a computer aided design and engineering system has been developed in the paper. The paper presents basic automation process principles including a graphical representation   network and calculation results, convenient user interface, automatic mode calculation, selection of transformer rated power and cross-section area of wires. The developed algorithm and program make it possible to save time and improve quality of project implementation.

  9. Teaching the Principles of Effective Online Course Design: What Works?

    Directory of Open Access Journals (Sweden)

    Clare Gormley

    2014-06-01

    Full Text Available While much has been written about the pedagogy and challenges of online learning, there is comparatively little research that advises how online course design competencies can be achieved. Certainly a growing range of course design resources is being created and made openly available, but there is a need to evaluate their actual impact on practice. This predominantly qualitative study describes the impact of two learning interventions – open online tutorials and a design and development workshop – aimed at introducing the fundamentals of online course design. Four online course developers at an Irish university were interviewed about their experiences creating multimedia-based online courses. Two of the developers were given access to targeted learning interventions and were subsequently interviewed about their experiences using those interventions. The main findings were that novice online course developers can potentially learn and apply design principles through a dedicated introductory phase, techniques that promote discussion of effective pedagogy, and ongoing collaboration in course design. These strategies could be adapted to specific contexts elsewhere.

  10. Achieving integration in mixed methods designs-principles and practices.

    Science.gov (United States)

    Fetters, Michael D; Curry, Leslie A; Creswell, John W

    2013-12-01

    Mixed methods research offers powerful tools for investigating complex processes and systems in health and health care. This article describes integration principles and practices at three levels in mixed methods research and provides illustrative examples. Integration at the study design level occurs through three basic mixed method designs-exploratory sequential, explanatory sequential, and convergent-and through four advanced frameworks-multistage, intervention, case study, and participatory. Integration at the methods level occurs through four approaches. In connecting, one database links to the other through sampling. With building, one database informs the data collection approach of the other. When merging, the two databases are brought together for analysis. With embedding, data collection and analysis link at multiple points. Integration at the interpretation and reporting level occurs through narrative, data transformation, and joint display. The fit of integration describes the extent the qualitative and quantitative findings cohere. Understanding these principles and practices of integration can help health services researchers leverage the strengths of mixed methods. © Health Research and Educational Trust.

  11. Five Principles for MOOC Design: With a Case Study

    Directory of Open Access Journals (Sweden)

    John R. Drake

    2015-05-01

    Full Text Available New web technologies have enabled online education to take on a massive scale, prompting many universities to create massively open online courses (MOOCs that take advantage of these technologies in a seemingly effortless manner. Designing a MOOC, however, is anything but trivial. It involves developing content, learning activities, and assessments to accommodate both the massiveness and openness of the course. To design an effective MOOC, instructors need to integrate both pedagogical and information systems theory. In this paper, we present a case study of a MOOC grant and a series of decisions made in its development. These decisions, when paired with the theoretical framework, suggest five principles – meaningful, engaging, measurable, accessible, and scalable – may be applicable to future MOOC development projects.

  12. Seeing is believing: good graphic design principles for medical research.

    Science.gov (United States)

    Duke, Susan P; Bancken, Fabrice; Crowe, Brenda; Soukup, Mat; Botsis, Taxiarchis; Forshee, Richard

    2015-09-30

    Have you noticed when you browse a book, journal, study report, or product label how your eye is drawn to figures more than to words and tables? Statistical graphs are powerful ways to transparently and succinctly communicate the key points of medical research. Furthermore, the graphic design itself adds to the clarity of the messages in the data. The goal of this paper is to provide a mechanism for selecting the appropriate graph to thoughtfully construct quality deliverables using good graphic design principles. Examples are motivated by the efforts of a Safety Graphics Working Group that consisted of scientists from the pharmaceutical industry, Food and Drug Administration, and academic institutions. Copyright © 2015 John Wiley & Sons, Ltd.

  13. IFE Power Plant design principles. Drivers. Solid state laser drivers

    International Nuclear Information System (INIS)

    Nakai, S.; Andre, M.; Krupke, W.F.; Mak, A.A.; Soures, J.M.; Yamanaka, M.

    1995-01-01

    The present status of solid state laser drivers for an inertial confinement thermonuclear fusion power plant is discussed. In particular, the feasibility of laser diode pumped solid state laser drivers from both the technical and economic points of view is briefly reviewed. Conceptual design studies showed that they can, in principle, satisfy the design requirements. However, development of new solid state materials with long fluorescence lifetimes and good thermal characteristics is a key issue for laser diode pumped solid state lasers. With the advent of laser diode pumping many materials which were abandoned in the past can presently be reconsidered as viable candidates. It is also concluded that it is important to examine the technical requirements for solid state lasers in relation to target performance criteria. The progress of laser diode pumped lasers in industrial applications should also be closely watched to provide additional information on the economic feasibility of this type of driver. 15 refs, 9 figs, 2 tabs

  14. Zebrafish housing systems: a review of basic operating principles and considerations for design and functionality.

    Science.gov (United States)

    Lawrence, Christian; Mason, Timothy

    2012-01-01

    The strategies for housing zebrafish used in biomedical research have evolved considerably over the past three decades. To keep pace with the rapid expansion and development of the zebrafish model system, the field has generally moved from keeping fish at the level of aquarium hobbyist to that of industrialized, recirculating aquaculture. Numerous commercial system vendors now offer increasingly sophisticated housing systems based on design principles that maximize the number of animals that can be housed in a given space footprint, and they are thus able to support large and diverse research programs. This review is designed to provide managers, lab animal veterinarians, investigators, and other parties responsible for care and use of these animals with a comprehensive overview of the basic operating and design principles of zebrafish housing systems. This information can be used to help plan the construction of new facilities and/or the upgrade and maintenance of existing operations.

  15. Usability Issues in the Design of Novice Programming Systems,

    Science.gov (United States)

    1996-08-01

    lists this as a design principle for novice programming environments. In traditional compiled languages, beginners are also confused by the need to...programming task external knowledge that might interfere with correct under- standing of the language. Most beginner programming errors can be...language for text editing, but [Curtis 1988] found that a textual pseudocode and graphical flowcharts were both bet- ter than natural language in program

  16. Synthetic RNAs for Gene Regulation: Design Principles and Computational Tools

    International Nuclear Information System (INIS)

    Laganà, Alessandro; Shasha, Dennis; Croce, Carlo Maria

    2014-01-01

    The use of synthetic non-coding RNAs for post-transcriptional regulation of gene expression has not only become a standard laboratory tool for gene functional studies but it has also opened up new perspectives in the design of new and potentially promising therapeutic strategies. Bioinformatics has provided researchers with a variety of tools for the design, the analysis, and the evaluation of RNAi agents such as small-interfering RNA (siRNA), short-hairpin RNA (shRNA), artificial microRNA (a-miR), and microRNA sponges. More recently, a new system for genome engineering based on the bacterial CRISPR-Cas9 system (Clustered Regularly Interspaced Short Palindromic Repeats), was shown to have the potential to also regulate gene expression at both transcriptional and post-transcriptional level in a more specific way. In this mini review, we present RNAi and CRISPRi design principles and discuss the advantages and limitations of the current design approaches.

  17. Synthetic RNAs for Gene Regulation: Design Principles and Computational Tools

    Energy Technology Data Exchange (ETDEWEB)

    Laganà, Alessandro [Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH (United States); Shasha, Dennis [Courant Institute of Mathematical Sciences, New York University, New York, NY (United States); Croce, Carlo Maria [Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH (United States)

    2014-12-11

    The use of synthetic non-coding RNAs for post-transcriptional regulation of gene expression has not only become a standard laboratory tool for gene functional studies but it has also opened up new perspectives in the design of new and potentially promising therapeutic strategies. Bioinformatics has provided researchers with a variety of tools for the design, the analysis, and the evaluation of RNAi agents such as small-interfering RNA (siRNA), short-hairpin RNA (shRNA), artificial microRNA (a-miR), and microRNA sponges. More recently, a new system for genome engineering based on the bacterial CRISPR-Cas9 system (Clustered Regularly Interspaced Short Palindromic Repeats), was shown to have the potential to also regulate gene expression at both transcriptional and post-transcriptional level in a more specific way. In this mini review, we present RNAi and CRISPRi design principles and discuss the advantages and limitations of the current design approaches.

  18. Web Interface Design Principles for Adults’ Self-Directed Learning

    Directory of Open Access Journals (Sweden)

    Mehmet FIRAT

    2016-10-01

    Full Text Available One of the most important features which e-learning tools and environments must possess within the scope of lifelong learning is self-directed learning, which can be considered as a form of self-learning. The aim of this study was to determine, based on the views and recommendations of experts, interface design principles for the development of educational web interfaces that will support the self-directed learning of adults. This descriptive study was conducted with the contribution of 12 academicians specializing in interface design and self-directed learning. Within the scope of the study, new interfaces features were identified based on an evaluation of the literature on interface designs for self-directed learning, and the views of subject experts. Based on the study results, it was determined that interface designs supporting self-directed learning must possess five basic features, which include being user-directed, ensuring variety, being supported by learning analytics, being motivational, and being sharing-oriented.

  19. Multimedia programming using Max/MSP and TouchDesigner

    CERN Document Server

    Lechner, Patrik

    2014-01-01

    If you want to learn how to use Max 6 and/or TouchDesigner, or work in audio-visual real-time processing, this is the book for you. It is intended for intermediate users of both programs and can be helpful for artists, designers, musicians, VJs, and researchers. A basic understanding of audio principles is advantageous.

  20. Pay for performance programs in Australia: a need for guiding principles.

    Science.gov (United States)

    Scott, Ian A

    2008-11-01

    Pay-for-performance (P4P) programs which reward clinical providers with incentive payments based on one or more measures of quality of care are now common in the United States and the United Kingdom and it is likely they will attract increasing interest in Australia. However, empirical evidence demonstrating effectiveness of such programs is limited and many existing programs have not had rigorous outcome evaluation. To maximise success, future P4P programs should incorporate the lessons and insights obtained from previous experience. Based on a review of published trials, program evaluations and position statements, the following principles that may guide future program design and implementation were synthesised: 1) formulate a rationale and a business case for P4P; 2) use established evidence-based performance measures; 3) use rigorous and verifiable methods of data collection and analysis; 4) define performance targets using absolute and relative thresholds; 5) use rewards that are sufficient, equitable and transparent; 6) address appropriateness of provider responses and avoid perverse incentives; 7) implement communication and feedback strategies; 8) use existing organisational structures to implement P4P programs; 9) attribute credit for performance to participants in ways that foster population-based perspectives; and 10) invest in outcomes and health service research. Recommendations flowing from these principles relevant to Australian settings are provided.

  1. Usability principles to design mobile workplace learning content

    Directory of Open Access Journals (Sweden)

    Alessia Messuti

    2015-04-01

    Full Text Available The article describes the design of a mobile workplace learning tool for trainers of the International Training Centre of the International Labour Organization. The motivation behind is to provide trainers with a practical tool that will enable them to recall information at the moment of need and continue to learn in context. On this purpose a set of visual augmented reality cards was created, taking into consideration the fundamental mobile learning and usability principles. The nature of the article is empirical as it reports an experiment carried out with trainers which aimed at testing cards usability and learnability. Results show that the integration of both online and offline strategies was perceived as an added value as trainers could choose to retrieve information as they mostly like; finally, it also resulted in high usability scores, an aspect that contributes to their effectiveness at the workplace.

  2. Synthetic Elucidation of Design Principles for Molecular Qubits

    Science.gov (United States)

    Graham, Michael James

    Quantum information processing (QIP) is an emerging computational paradigm with the potential to enable a vast increase in computational power, fundamentally transforming fields from structural biology to finance. QIP employs qubits, or quantum bits, as its fundamental units of information, which can exist in not just the classical states of 0 or 1, but in a superposition of the two. In order to successfully perform QIP, this superposition state must be sufficiently long-lived. One promising paradigm for the implementation of QIP involves employing unpaired electrons in coordination complexes as qubits. This architecture is highly tunable and scalable, however coordination complexes frequently suffer from short superposition lifetimes, or T2. In order to capitalize on the promise of molecular qubits, it is necessary to develop a set of design principles that allow the rational synthesis of complexes with sufficiently long values of T2. In this dissertation, I report efforts to use the synthesis of series of complexes to elucidate design principles for molecular qubits. Chapter 1 details previous work by our group and others in the field. Chapter 2 details the first efforts of our group to determine the impact of varying spin and spin-orbit coupling on T2. Chapter 3 examines the effect of removing nuclear spins on coherence time, and reports a series of vanadyl bis(dithiolene) complexes which exhibit extremely long coherence lifetimes, in excess of the 100 mus threshold for qubit viability. Chapters 4 and 5 form two complimentary halves of a study to determine the exact relationship between electronic spin-nuclear spin distance and the effect of the nuclear spins on T2. Finally, chapter 6 suggests next directions for the field as a whole, including the potential for work in this field to impact the development of other technologies as diverse as quantum sensors and magnetic resonance imaging contrast agents.

  3. Programming languages for circuit design.

    Science.gov (United States)

    Pedersen, Michael; Yordanov, Boyan

    2015-01-01

    This chapter provides an overview of a programming language for Genetic Engineering of Cells (GEC). A GEC program specifies a genetic circuit at a high level of abstraction through constraints on otherwise unspecified DNA parts. The GEC compiler then selects parts which satisfy the constraints from a given parts database. GEC further provides more conventional programming language constructs for abstraction, e.g., through modularity. The GEC language and compiler is available through a Web tool which also provides functionality, e.g., for simulation of designed circuits.

  4. PRINCIPLE "EARLY MATCHING" AERODYNAMIC DESIGN AIRCRAFT WITH LANDING GEAR HOVERCRAFT

    Directory of Open Access Journals (Sweden)

    V. P. Morozov

    2015-01-01

    Full Text Available The principle of "early matching" aircraft aerohydrodynamic layouts with air cushion landing gear is suggested. Application of this principle is considered as an example of adaptation to the ball screw base circuit of light transport aircraft. The principle, other than weight, aerodynamic, technological and operational requirements includes additional project activities related to the installation of ball screws.

  5. Three Principles of Perception for Instructional Interface Design.

    Science.gov (United States)

    Lohr, Linda L.

    2000-01-01

    Discusses graphical user interfaces used for instructional purposes in educational environments, which promote learning goals, and in support environments, which promote performance goals. Explains three key principles of perception and gives guidelines for their use, including the figure/ground principle, the hierarchy principle, and the gestalt…

  6. Design Minimalism in Robotics Programming

    Directory of Open Access Journals (Sweden)

    Anthony Cowley

    2008-11-01

    Full Text Available With the increasing use of general robotic platforms in different application scenarios, modularity and reusability have become key issues in effective robotics programming. In this paper, we present a minimalist approach for designing robot software, in which very simple modules, with well designed interfaces and very little redundancy can be connected through a strongly typed framework to specify and execute different robotics tasks.

  7. Design Minimalism in Robotics Programming

    Directory of Open Access Journals (Sweden)

    Anthony Cowley

    2006-03-01

    Full Text Available With the increasing use of general robotic platforms in different application scenarios, modularity and reusability have become key issues in effective robotics programming. In this paper, we present a minimalist approach for designing robot software, in which very simple modules, with well designed interfaces and very little redundancy can be connected through a strongly typed framework to specify and execute different robotics tasks.

  8. EDF EPR project: operating principles validation and human factor engineering program

    International Nuclear Information System (INIS)

    Lefebvre, B.; Berard, E.; Arpino, J.-M.

    2005-01-01

    This article describes the specificities of the operating principles chosen by EDF for the EPR project as a result of an extensive Human Factor Engineering program successfully implemented in an industrial project context. The design process and its achievements benefit of the EDF experience feedback not only in term of NPP operation - including the fully computerized control room of the N4-serie - but also in term of NPP designer. The elements exposed hereafter correspond to the basic design phase of EPR HMI which has been completed and successfully validated by the end of 2003. The article aims to remind the context of the project which basically consists in designing a modern and efficient HMI taking into account the operating needs while relying on proven and reliable technologies. The Human Factor Engineering program implemented merges these both aspects by : 1) being fully integrated within the project activities and scheduling; 2) efficiently taking into account the users needs as well as the feasibility constraints by relying on a multidisciplinary design team including HF specialists, I and C specialists, Process specialists and experienced operator representatives. The resulting design process makes a wide use of experience feedback and experienced operator knowledge to complete largely the existing standards for providing a fully useable and successful design method in an industrial context. The article underlines the design process highlights that largely contribute to the successful implementation of a Human Factor Engineering program for EPR. (authors)

  9. Virus-inspired design principles of nanoparticle-based bioagents.

    Directory of Open Access Journals (Sweden)

    Hongyan Yuan

    Full Text Available The highly effectiveness and robustness of receptor-mediated viral invasion of living cells shed lights on the biomimetic design of nanoparticle(NP-based therapeutics. Through thermodynamic analysis, we elucidate that the mechanisms governing both the endocytic time of a single NP and the cellular uptake can be unified into a general energy-balance framework of NP-membrane adhesion and membrane deformation. Yet the NP-membrane adhesion strength is a globally variable quantity that effectively regulates the NP uptake rate. Our analysis shows that the uptake rate interrelatedly depends on the particle size and ligand density, in contrast to the widely reported size effect. Our model predicts that the optimal radius of NPs for maximal uptake rate falls in the range of 25-30 nm, and optimally several tens of ligands should be coated onto NPs. These findings are supported by both recent experiments and typical viral structures, and serve as fundamental principles for the rational design of NP-based nanomedicine.

  10. Silver Nanoclusters: From Design Principles to Practical Applications

    KAUST Repository

    Abdulhalim, Lina G.

    2015-12-08

    A strategy based on reticulating metal ions and organic ligands into atomically precise gold and silver nanoclusters (NCs) with high monodispersity has been advanced to a point that allows the design of NCs with strict stoichiometries, functionalities and valence. Of the Ag NCs discovered, Ag44 is the most studied, not only due to its high absorption that transcends the visible spectrum suitable for photovoltaics but also because of its long excited state lifetime, as revealed by nanosecond transient absorption spectroscopy. A major principle discovered in this dissertation is the ability to produce Ag44 in scalable amounts and with high stability in addition to modulation of the functional groups of the organic ligands via a fast and complete ligand exchange process. This new discovery has led to the development of synthetic designs in which new sizes were obtained by varying the reaction parameters (e.g., ligands functionality, reaction temperature and time), namely, Ag29 using dithiols and phosphines. The synthesized NCs possess tetravalent functionalities that facilitate their crystallization and characterization. Furthermore, Ag29 glows red and is therefore a possible candidate for sensing and imaging applications.

  11. Design principles for solid-state lithium superionic conductors.

    Science.gov (United States)

    Wang, Yan; Richards, William Davidson; Ong, Shyue Ping; Miara, Lincoln J; Kim, Jae Chul; Mo, Yifei; Ceder, Gerbrand

    2015-10-01

    Lithium solid electrolytes can potentially address two key limitations of the organic electrolytes used in today's lithium-ion batteries, namely, their flammability and limited electrochemical stability. However, achieving a Li(+) conductivity in the solid state comparable to existing liquid electrolytes (>1 mS cm(-1)) is particularly challenging. In this work, we reveal a fundamental relationship between anion packing and ionic transport in fast Li-conducting materials and expose the desirable structural attributes of good Li-ion conductors. We find that an underlying body-centred cubic-like anion framework, which allows direct Li hops between adjacent tetrahedral sites, is most desirable for achieving high ionic conductivity, and that indeed this anion arrangement is present in several known fast Li-conducting materials and other fast ion conductors. These findings provide important insight towards the understanding of ionic transport in Li-ion conductors and serve as design principles for future discovery and design of improved electrolytes for Li-ion batteries.

  12. 75 FR 80571 - Core Principles and Other Requirements for Designated Contract Markets

    Science.gov (United States)

    2010-12-22

    ... Part II Commodity Futures Trading Commission 17 CFR Parts 1, 16, and 38 Core Principles and Other... CFR Parts 1, 16, and 38 RIN 3038-AD09 Core Principles and Other Requirements for Designated Contract... Principles 1. Subpart B--Designation as Contract Market 2. Subpart C--Compliance With Rules i. Proposed Sec...

  13. 78 FR 32988 - Core Principles and Other Requirements for Designated Contract Markets; Correction

    Science.gov (United States)

    2013-06-03

    ... COMMODITY FUTURES TRADING COMMISSION 17 CFR Part 38 RIN 3038-AD09 Core Principles and Other... regarding Core Principles and Other Requirements for Designated Contract Markets by inserting a missing... regarding Core Principles and Other Requirements for Designated Contract Markets (77 FR 36612, June 19, 2012...

  14. Defining DSL design principles for enhancing the requirements elicitation process

    Directory of Open Access Journals (Sweden)

    Gustavo Arroyo

    2012-03-01

    Full Text Available La Elicitación de Requisitos propicia el entendimiento de las necesidades de los usuarios con respecto a un desarrollo de software. Los métodos que se emplean provienen de las ciencias sociales por lo que se carece de una retroalimentación ejecutable. Consecuentemente, la primera versión del software podría no cumplir con las expectativas. El uso de DSLs como herramientas para el descubrimiento de requisitos es una idea aceptada, desafortunadamente, muy pocos trabajos en la literatura se enfocan en la definición de principios de diseño de DSLs. En este trabajo planteamos principios de diseño de DSLs orientados a la elicitación de requisitos, enseguida, generamos casos de prueba en ANTLR, Ruby y Curry. También, enunciamos el perfil que debe tener el nuevo analista de software. Con ello, se incrementa la retroalimentación entre los involucrados en el desarrollo de software y se mejora el producto.Requirements elicitation is concerned with learning and understanding the needs of users w.r.t. a new software development. Frequently the methods employed for requirements elicitation are adapted from areas like social sciences that do not include executable (prototype based on feedback. As a consequence, it is relatively common to discover that the first release does not fit the requirements defined at the beginning of the project. Using domain-specific languages (DSLs as an auxiliary tool for requirements elicitation is a commonly well accepted idea. Unfortunately, there are few works in the literature devoted to the definition of design principles for DSLs to be experienced in the frameworks for DSL developing such as ANTLR, Ruby, and Curry. We propose design principles for the DSL development (regardless of paradigm which are sufficient to model the domain in a requirements phase. Further more we enunciate a new profile for the requirements analyst and a set of elicitation steps. The use of DSLs not only giveus an immediate feedback with

  15. Computer-based teaching module design: principles derived from learning theories.

    Science.gov (United States)

    Lau, K H Vincent

    2014-03-01

    The computer-based teaching module (CBTM), which has recently gained prominence in medical education, is a teaching format in which a multimedia program serves as a single source for knowledge acquisition rather than playing an adjunctive role as it does in computer-assisted learning (CAL). Despite empirical validation in the past decade, there is limited research into the optimisation of CBTM design. This review aims to summarise research in classic and modern multimedia-specific learning theories applied to computer learning, and to collapse the findings into a set of design principles to guide the development of CBTMs. Scopus was searched for: (i) studies of classic cognitivism, constructivism and behaviourism theories (search terms: 'cognitive theory' OR 'constructivism theory' OR 'behaviourism theory' AND 'e-learning' OR 'web-based learning') and their sub-theories applied to computer learning, and (ii) recent studies of modern learning theories applied to computer learning (search terms: 'learning theory' AND 'e-learning' OR 'web-based learning') for articles published between 1990 and 2012. The first search identified 29 studies, dominated in topic by the cognitive load, elaboration and scaffolding theories. The second search identified 139 studies, with diverse topics in connectivism, discovery and technical scaffolding. Based on their relative representation in the literature, the applications of these theories were collapsed into a list of CBTM design principles. Ten principles were identified and categorised into three levels of design: the global level (managing objectives, framing, minimising technical load); the rhetoric level (optimising modality, making modality explicit, scaffolding, elaboration, spaced repeating), and the detail level (managing text, managing devices). This review examined the literature in the application of learning theories to CAL to develop a set of principles that guide CBTM design. Further research will enable educators to

  16. Design Principles for the Information Architecture of a SMET Education Digital Library.

    Science.gov (United States)

    Dong, Andy; Agogino, Alice M.

    This implementation paper introduces principles for the information architecture of an educational digital library, principles that address the distinction between designing digital libraries for education and designing digital libraries for information retrieval in general. Design is a key element of any successful product. Good designers and…

  17. EMERGING ENGINEERING PRINCIPLES FOR YIELD IMPROVEMENT IN MICROBIAL CELL DESIGN

    Directory of Open Access Journals (Sweden)

    Santiago Comba

    2012-10-01

    Full Text Available Metabolic Engineering has undertaken a rapid transformation in the last ten years making real progress towards the production of a wide range of molecules and fine chemicals using a designed cellular host. However, the maximization of product yields through pathway optimization is a constant and central challenge of this field. Traditional methods used to improve the production of target compounds from engineered biosynthetic pathways in non-native hosts include: codon usage optimization, elimination of the accumulation of toxic intermediates or byproducts, enhanced production of rate-limiting enzymes, selection of appropriate promoter and ribosome binding sites, application of directed evolution of enzymes, and chassis re-circuit. Overall, these approaches tend to be specific for each engineering project rather than a systematic practice based on a more generalizable strategy. In this mini-review, we highlight some novel and extensive approaches and tools intended to address the improvement of a target product formation, founded in sophisticated principles such as dynamic control, pathway genes modularization, and flux modeling.

  18. Emerging engineering principles for yield improvement in microbial cell design

    Directory of Open Access Journals (Sweden)

    Santiago Comba

    2012-10-01

    Full Text Available Metabolic Engineering has undertaken a rapid transformation in the last ten years making real progress towards the production of a wide range of molecules and fine chemicals using a designed cellular host. However, the maximization of product yields through pathway optimization is a constant and central challenge of this field. Traditional methods used to improve the production of target compounds from engineered biosynthetic pathways in non-native hosts include: codon usage optimization, elimination of the accumulation of toxic intermediates or byproducts, enhanced production of rate-limiting enzymes, selection of appropriate promoter and ribosome binding sites, application of directed evolution of enzymes, and chassis re-circuit. Overall, these approaches tend to be specific for each engineering project rather than a systematic practice based on a more generalizable strategy. In this mini-review, we highlight some novel and extensive approaches and tools intended to address the improvement of a target product formation, founded in sophisticated principles such as dynamic control, pathway genes modularization, and flux modeling.

  19. Principles for designing and delivering psychosocial and mental healthcare.

    Science.gov (United States)

    Williams, Richard; Kemp, V

    2018-03-08

    The development of the UK's military policy includes the potential for military organisations to deploy in support of humanitarian aid operations. This paper offers an overview of the risks to people's mental health of their exposure to emergencies, major incidents, disasters, terrorism, displacement, postconflict environments in which humanitarian aid is delivered, and deployments to conflict zones. It summarises the psychosocial approach recommended by many contemporary researchers and practitioners. It differentiates the extremely common experience of distress from the mental disorders that people who are affected may develop and introduces the construct of psychosocial resilience. The authors recognise the importance of trajectories of response in separating people who are distressed and require psychosocial care from those who require mental healthcare. Finally, this paper summarises a strategic approach to designing, planning and providing psychosocial and mental healthcare, provides a model of care and outlines the principles for early psychosocial interventions that do not require training in mental healthcare to deliver them. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  20. Design principles of a conditional futile cycle exploited for regulation.

    Science.gov (United States)

    Tolla, Dean A; Kiley, Patricia J; Lomnitz, Jason G; Savageau, Michael A

    2015-07-01

    In this report, we characterize the design principles of futile cycling in providing rapid adaptation by regulatory proteins that act as environmental sensors. In contrast to the energetically wasteful futile cycles that are avoided in metabolic pathways, here we describe a conditional futile cycle exploited for a regulatory benefit. The FNR (fumarate and nitrate reduction) cycle in Escherichia coli operates under two regimes - a strictly futile cycle in the presence of O2 and as a pathway under anoxic conditions. The computational results presented here use FNR as a model system and provide evidence that cycling of this transcription factor and its labile sensory cofactor between active and inactive states affords rapid signaling and adaptation. We modify a previously developed mechanistic model to examine a family of FNR models each with different cycling speeds but mathematically constrained to be otherwise equivalent, and we identify a trade-off between energy expenditure and response time that can be tuned by evolution to optimize cycling rate of the FNR system for a particular ecological context. Simulations mimicking experiments with proposed double mutant strains offer suggestions for experimentally testing our predictions and identifying potential fitness effects. Our approach provides a computational framework for analyzing other conditional futile cycles, which when placed in their larger biological context may be found to confer advantages to the organism.

  1. Development of design principles for automated systems in transport control.

    Science.gov (United States)

    Balfe, Nora; Wilson, John R; Sharples, Sarah; Clarke, Theresa

    2012-01-01

    This article reports the results of a qualitative study investigating attitudes towards and opinions of an advanced automation system currently used in UK rail signalling. In-depth interviews were held with 10 users, key issues associated with automation were identified and the automation's impact on the signalling task investigated. The interview data highlighted the importance of the signallers' understanding of the automation and their (in)ability to predict its outputs. The interviews also covered the methods used by signallers to interact with and control the automation, and the perceived effects on their workload. The results indicate that despite a generally low level of understanding and ability to predict the actions of the automation system, signallers have developed largely successful coping mechanisms that enable them to use the technology effectively. These findings, along with parallel work identifying desirable attributes of automation from the literature in the area, were used to develop 12 principles of automation which can be used to help design new systems which better facilitate cooperative working. The work reported in this article was completed with the active involvement of operational rail staff who regularly use automated systems in rail signalling. The outcomes are currently being used to inform decisions on the extent and type of automation and user interfaces in future generations of rail control systems.

  2. Principles underlying rational design of live attenuated influenza vaccines

    Science.gov (United States)

    Jang, Yo Han

    2012-01-01

    Despite recent innovative advances in molecular virology and the developments of vaccines, influenza virus remains a serious burden for human health. Vaccination has been considered a primary countermeasure for prevention of influenza infection. Live attenuated influenza vaccines (LAIVs) are particularly attracting attention as an effective strategy due to several advantages over inactivated vaccines. Cold-adaptation, as a classical means for attenuating viral virulence, has been successfully used for generating safe and effective donor strains of LAIVs against seasonal epidemics and occasional pandemics. Recently, the advent of reverse genetics technique expedited a variety of rational strategies to broaden the pool of LAIVs. Considering the breadth of antigenic diversity of influenza virus, the pool of LAIVs is likely to equip us with better options for controlling influenza pandemics. With a brief reflection on classical attenuating strategies used at the initial stage of development of LAIVs, especially on the principles underlying the development of cold-adapted LAIVs, we further discuss and outline other attenuation strategies especially with respect to the rationales for attenuation, and their practicality for mass production. Finally, we propose important considerations for a rational vaccine design, which will provide us with practical guidelines for improving the safety and effectiveness of LAIVs. PMID:23596576

  3. Design Principles and Algorithms for Air Traffic Arrival Scheduling

    Science.gov (United States)

    Erzberger, Heinz; Itoh, Eri

    2014-01-01

    This report presents design principles and algorithms for building a real-time scheduler of arrival aircraft based on a first-come-first-served (FCFS) scheduling protocol. The algorithms provide the conceptual and computational foundation for the Traffic Management Advisor (TMA) of the Center/terminal radar approach control facilities (TRACON) automation system, which comprises a set of decision support tools for managing arrival traffic at major airports in the United States. The primary objective of the scheduler is to assign arrival aircraft to a favorable landing runway and schedule them to land at times that minimize delays. A further objective of the scheduler is to allocate delays between high-altitude airspace far away from the airport and low-altitude airspace near the airport. A method of delay allocation is described that minimizes the average operating cost in the presence of errors in controlling aircraft to a specified landing time. This report is a revision of an earlier paper first presented as part of an Advisory Group for Aerospace Research and Development (AGARD) lecture series in September 1995. The authors, during vigorous discussions over the details of this paper, felt it was important to the air-trafficmanagement (ATM) community to revise and extend the original 1995 paper, providing more detail and clarity and thereby allowing future researchers to understand this foundational work as the basis for the TMA's scheduling algorithms.

  4. Design Principles for Online Instruction: A New Kind of Classroom

    Directory of Open Access Journals (Sweden)

    Neil TOPORSKI

    2004-01-01

    Full Text Available In the 1900’s, distance education attempted to mimic the traditional classroom lecture via the transmission of live or “canned” broadcasts, regardless of the technologies used: satellite, television, film, or radio. These kinds of media predisposed DE to closely adhere to the lecture (sit and absorb model, where content was disseminated in about the same time constraints as a traditional class: taught at scheduled times throughout the week–almost anywhere but not always anytime. Moreover, the modes of presentation in classic DE seemed to hinder the kinds of human interactions normally experienced in the traditional classroom, fostering individualized and isolated learning experiences.Online learning is a hybrid between the traditional classroom and the DE experience. Like the traditional classroom, instruction is teacher-facilitated. The student is enrolled in a conventional course with topic (lecture presentations, reading and homework assignments, classroom discussions, and class projects. Unlike the traditional classroom, courses are web-based and distributed from a distance, using an assortment of synchronous and asynchronous computer technologies and offered anywhere and anytime. In this way, online learning is different from the classic DE model by encouraging decentralized and collaborative learning environments. So that in this presentation will be discuss design principles for online instruction as being a new kind of classroom.

  5. Design principles for simulation games for learning clinical reasoning: A design-based research approach.

    Science.gov (United States)

    Koivisto, J-M; Haavisto, E; Niemi, H; Haho, P; Nylund, S; Multisilta, J

    2018-01-01

    Nurses sometimes lack the competence needed for recognising deterioration in patient conditions and this is often due to poor clinical reasoning. There is a need to develop new possibilities for learning this crucial competence area. In addition, educators need to be future oriented; they need to be able to design and adopt new pedagogical innovations. The purpose of the study is to describe the development process and to generate principles for the design of nursing simulation games. A design-based research methodology is applied in this study. Iterative cycles of analysis, design, development, testing and refinement were conducted via collaboration among researchers, educators, students, and game designers. The study facilitated the generation of reusable design principles for simulation games to guide future designers when designing and developing simulation games for learning clinical reasoning. This study makes a major contribution to research on simulation game development in the field of nursing education. The results of this study provide important insights into the significance of involving nurse educators in the design and development process of educational simulation games for the purpose of nursing education. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. How bioethics principles can aid design of electronic health records to accommodate patient granular control.

    Science.gov (United States)

    Meslin, Eric M; Schwartz, Peter H

    2015-01-01

    Ethics should guide the design of electronic health records (EHR), and recognized principles of bioethics can play an important role. This approach was recently adopted by a team of informaticists who are designing and testing a system where patients exert granular control over who views their personal health information. While this method of building ethics in from the start of the design process has significant benefits, questions remain about how useful the application of bioethics principles can be in this process, especially when principles conflict. For instance, while the ethical principle of respect for autonomy supports a robust system of granular control, the principles of beneficence and nonmaleficence counsel restraint due to the danger of patients being harmed by restrictions on provider access to data. Conflict between principles has long been recognized by ethicists and has even motivated attacks on approaches that state and apply principles. In this paper, we show how using ethical principles can help in the design of EHRs by first explaining how ethical principles can and should be used generally, and then by discussing how attention to details in specific cases can show that the tension between principles is not as bad as it initially appeared. We conclude by suggesting ways in which the application of these (and other) principles can add value to the ongoing discussion of patient involvement in their health care. This is a new approach to linking principles to informatics design that we expect will stimulate further interest.

  7. Distributed learning process: principles of design and implementation

    Directory of Open Access Journals (Sweden)

    G. N. Boychenko

    2016-01-01

    authors determines specifi cs of educational objectives, learning content and distributed learning lifecycle design, approaches to implementing learning scenarios, as well as the functions and roles of students and teachers in a distributed interaction. Main advantage of the author’s methodology is that it allows to use various paradigms (behaviorism, cognitivism, constructivism in instructional design. It is applicable to all levels of distributed learning: traditional face-to-face learning with ICT support, blended learning, distance learning in virtual learning environments.Conclusion. Methodology presented by the authors has been tested in the professional teachers training programs for IT-teachers to be at the Novokuznetsk Institute (Branch of Kemerovo State University in the curriculum of disciplines ‘Educational process management informatization’, ‘Innovative methods and technologies for e-learning’ and ‘Distance learning organization’.

  8. Transformer design principles with applications to core-form power transformers

    CERN Document Server

    Del Vecchio, Robert M; Feeney, Mary-Ellen F

    2001-01-01

    Transformer Design Principles presents the theory of transformer operation and the methods and techniques of designing them. It emphasizes the physical principles and mathematical tools for simulating transformer behavior, including modern computer techniques. The scope of the book includes types of construction, circuit analysis, mechanical aspects of design, high voltage insulation requirements, and cooling design. The authors also address test procedures and reliability methods to assure successful design and discuss the economic analysis of designs. Summarizing material currently scattered

  9. Designing and Programming CICS Applications

    CERN Document Server

    Horswill, John

    2011-01-01

    CICS is an application server that delivers industrial-strength, online transaction management for critical enterprise applications. Proven in the market for over 30 years with many of the world's leading businesses, CICS enables today's customers to modernize and extend their applications to take advantage of the opportunities provided by e-business while maximizing the benefits of their existing investments. Designing and Programming CICS Applications will benefit a diverse audience. It introduces new users of IBM's mainframe (OS/390) to CICS features. It shows experienced users how t

  10. Temporal Evolution of Design Principles in Engineering Systems: Analogies with Human Evolution

    DEFF Research Database (Denmark)

    Deb, Kalyanmoy; Bandaru, Sunith; Tutum, Cem Celal

    2012-01-01

    constructed later during optimization. Interestingly, there exists a simile between evolution of design principles with that of human evolution. Such information about the hierarchy of key design principles should enable designers to have a deeper understanding of their problems.......Optimization of an engineering system or component makes a series of changes in the initial random solution(s) iteratively to form the final optimal shape. When multiple conflicting objectives are considered, recent studies on innovization revealed the fact that the set of Pareto-optimal solutions...... portray certain common design principles. In this paper, we consider a 14-variable bi-objective design optimization of a MEMS device and identify a number of such common design principles through a recently proposed automated innovization procedure. Although these design principles are found to exist...

  11. User-Centered Design of GPU-Based Shader Programs

    DEFF Research Database (Denmark)

    Kraus, Martin

    2012-01-01

    In the context of game engines with graphical user interfaces, shader programs for GPUs (graphics processing units) are an asset for game development that is often used by artists and game developers without knowledge of shader programming. Thus, it is important that non-programmers are enabled...... to explore and exploit the full potential of shader programs. To this end, we develop principles and guidelines for the design of usercentered graphical interfaces for shaders. With the help of several examples, we show how the requirements of a user-centered interface design influence the choice of widgets...

  12. Large Coil Program magnetic system design study

    International Nuclear Information System (INIS)

    Moses, S.D.; Johnson, N.E.

    1977-01-01

    The primary objective of the Large Coil Program (LCP) is to demonstrate the reliable operation of large superconducting coils to provide a basis for the design principles, materials, and fabrication techniques proposed for the toroidal magnets for the THE NEXT STEP (TNS) and other future tokamak devices. This paper documents a design study of the Large Coil Test Facility (LCTF) in which the structural response of the Toroidal Field (TF) Coils and the supporting structure was evaluated under simulated reactor conditions. The LCP test facility structural system consists of six TF Coils, twelve coil-to-coil torsional restraining beams (torque rings), a central bucking post with base, and a Pulse Coil system. The NASTRAN Finite Element Structural Analysis computer Code was utilized to determine the distribution of deflections, forces, and stresses for each of the TF Coils, torque rings, and the central bucking post. Eleven load conditions were selected to represent probable test operations. Pulse Coils suspended in the bore of the test coil were energized to simulate the pulsed field environment characteristic of the TNS reactor system. The TORMAC Computer Code was utilized to develop the magnetic forces in the TF Coils for each of the eleven loading conditions examined, with or without the Pulse Coils energized. The TORMAC computer program output forces were used directly as input load conditions for the NASTRAN analyses. Results are presented which demonstrate the reliability of the LCTF under simulated reactor operating conditions

  13. Assessment Of Co60 Industrial Irradiators According To Basic Design Principles

    Directory of Open Access Journals (Sweden)

    El-Sayed Mohamed El Refaie

    2017-04-01

    Full Text Available Ensuring safe and easy operation providing relative uniform dose in the product and maximizing radiation utilization are the basic design principles for each Co60 industrial irradiator to maintain radiation safety. The study shows an assessment for four industrial irradiators to determine which active results were been maintained by using basic design principles. Different designs elements of the chosen irradiators have been illustrated and studied. The study shows that IRASM and ROBO industrial irradiators satisfy all basic design principles. IAEA-NR3772 irradiator maintains only two of the three basic design principles due to rotating door. Brevion irradiator satisfies only the principle of relative uniform radiation dose in product. Without affecting radiation safety this study proposes a new design of the irradiator to maximize energy utilization by adding a new track for low density products and also a static irradiation for cultural heritage beside the main track of high density products.

  14. Seismic design and performance of nuclear safety related RC structures based on new seismic design principle

    International Nuclear Information System (INIS)

    Murugan, R.; Sivathanu Pillai, C.; Chattopadhyaya, S.; Sundaramurthy, C.

    2011-01-01

    Full text: Seismic design of safety related Reinforced Concrete (RC) structures of Nuclear power plants (NPP) in India as per the present AERB codal procedures tries to ensure predominantly elastic behaviour under OBE so that the features of Nuclear Power Plant (NPP) necessary for continued safe operation are designed to remain functional and prevent accident (collapse) of NPP under SSE for which certain Structures, Systems and Components (SSCs) those are necessary to ensure the capability to shut down the reactor safely, are designed to remain functional. While the seismic design principles of non safety related structures as per Indian code (IS 1893-2002) are ensuring elastic behaviour under DBE and inelastic behaviour under MCE by utilizing ductility and energy dissipation capacity of the structure effectively. The design principle of AERB code is ensuring elastic behaviour under OBE and is not enlightening much inference about the overall structural behaviour under SSE (only ensuring the capability of certain SSCs required for safe shutdown of reactor). Various buildings and structures of Indian Nuclear power plant are classified from the basis of associated safety functions in a descending order in according with their roles in preventions and mitigation of an accident or support functions for prevention. This paper covers a comprehensive seismic analysis and design methodology based on the AERB codal provisions followed for safety related RC structure taking Diesel Generator Building of PFBR as a case study and study and investigates its performance under OBE and SSE by carrying out Non-linear static Pushover analysis. Based on the analysis, observed variations, recommendations are given for getting the desired performance level so as to implement performance based design in the future NPP design

  15. Designing Next Generation Rechargeable Battery Materials from First-Principles

    Science.gov (United States)

    Kim, Soo

    Technology has advanced rapidly, especially in the twenty-first century, influencing our day-to-day life on unprecedented levels. Most such advances in technology are closely linked to, and often driven by, the discovery and design of new materials. It follows that the discovery of new materials can not only improve existing technologies but also lead to revolutionary ones. In particular, there is a growing need to develop new energy materials that are reliable, clean, and affordable for emerging applications such as portable electronics, electric vehicles, and power grid systems. Many researchers have been actively searching for more cost-effective and clean electrode materials for lithium-ion batteries (LIBs) during the last few decades. These new electrode materials are also required to achieve higher electrochemical performance, compared to the already commercialized electrodes. Unfortunately, discovering the next sustainable energy materials based on a traditional 'trial-and-error' method via experiment would be extremely slow and difficult. In the last two decades, computational compilations of battery material properties such as voltage, diffusivity, and phase stability against irreversible phase transformation(s) using first-principles density functional theory (DFT) calculations have helped researchers to understand the underlying mechanism in many oxide materials that are used as LIB electrodes. Here, we have examined the (001) and (111) surface structures of LiMn2O4 (LMO) spinel cathode materials using DFT calculations within the generalized gradient approximation (GGA) + U approach. Our theoretical results explain the observation of a wide spectrum of polyhedral shapes between (001)- and (111)-dominated LMO particles in experiments, which can be described by the narrow range of surface energies and their sensitivity to synthesis conditions. We further show that single-layer graphene coatings help suppress manganese dissolution in LMO by chemically

  16. Designing MOOC: a shared view on didactical principles

    NARCIS (Netherlands)

    Stoyanov, Slavi; De Vries, Fred

    2018-01-01

    The innovative impact of the paper can be highlighted by the following statements: 1. Applying the Group Concept Mapping, a non-traditional and power research methodology for objectively identifying the shared vision of a group of experts on MOOC didactical principles. 2. Defining MOOC didactical

  17. Silver Nanoclusters: From Design Principles to Practical Applications

    KAUST Repository

    AbdulHalim, Lina G.

    2015-01-01

    transient absorption spectroscopy. A major principle discovered in this dissertation is the ability to produce Ag44 in scalable amounts and with high stability in addition to modulation of the functional groups of the organic ligands via a fast and complete

  18. Design Principles for the Development of the Balanced Scorecard

    Science.gov (United States)

    Keser Ozmantar, Zehra; Gedikoglu, Tokay

    2016-01-01

    Purpose: The purpose of this paper is to investigate the development and implementation process of the balanced scorecard (BSC) approach in an educational institution in the context of the Turkish educational system. It also aims, on the basis of the results of the applications in a particular school, to define principles through which the…

  19. Design of Learning Objects for Concept Learning: Effects of Multimedia Learning Principles and an Instructional Approach

    Science.gov (United States)

    Chiu, Thomas K. F.; Churchill, Daniel

    2016-01-01

    Literature suggests using multimedia learning principles in the design of instructional material. However, these principles may not be sufficient for the design of learning objects for concept learning in mathematics. This paper reports on an experimental study that investigated the effects of an instructional approach, which includes two teaching…

  20. Representing Clarity: Using Universal Design Principles to Create Effective Hybrid Course Learning Materials

    Science.gov (United States)

    Spiegel, Cheri Lemieux

    2012-01-01

    This article describes how the author applied principles of universal design to hybrid course materials to increase student understanding and, ultimately, success. Pulling the three principles of universal design--consistency, color, and icon representation--into the author's Blackboard course allowed her to change the types of reading skills…

  1. 10 CFR 435.6 - Sustainable principles for siting, design and construction. [Reserved

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Sustainable principles for siting, design and construction. [Reserved] 435.6 Section 435.6 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY STANDARDS...-Rise Residential Buildings. § 435.6 Sustainable principles for siting, design and construction...

  2. 10 CFR 433.6 - Sustainable principles for siting, design and construction. [Reserved

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Sustainable principles for siting, design and construction. [Reserved] 433.6 Section 433.6 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY STANDARDS... BUILDINGS § 433.6 Sustainable principles for siting, design and construction. [Reserved] ...

  3. The principles of design of a shallow disposal site for low and intermediate level radioactive wastes

    International Nuclear Information System (INIS)

    Holmes, R.E.

    1985-01-01

    This paper addresses the principles of design of a shallow disposal site for low and intermediate level radioactive wastes. The objective of the author is to review the need for shallow land disposal facilities in the UK and to propose design principles which will protect the public and operatives from excessive risk. It is not the intent of the author to present a detailed design of facility which will meet the design standards proposed although such a design is feasible and within the scope of currently available technology. The principles and standards proposed in this paper are not necessarily those of PPC Consultant Services Ltd. or NEI Waste Technologies Ltd. (author)

  4. Workspace Design: A case study applying participatory design principles of healthy workplaces in an industrial setting

    DEFF Research Database (Denmark)

    Broberg, Ole

    2010-01-01

    The Danish Workspace Design (WSD) research program is aimed to develop and trial a potential new concept for ergonomists and other workplace consultants who are to engage in socio-technical design processes. The objective of this paper is to report on the trial of the workspace design concept...... in a case involving the design and implementation of a new mixing technology in an industrial plant. The case showed how the WSD concept can contribute to an engineering design process. The WSD team took the role as workspace designer and by the participatory workshops achieved an impact on the technology...... project. In the role as workspace designer it was important for the WSD team to make sure that the achievements in the workshops were “transmitted” to and sustained in the ordinary engineering design process. In this case, it turned out that the artefacts such as a layout game board and documents...

  5. Design Principles for Serious Video Games in Mathematics Education: From Theory to Practice

    OpenAIRE

    Konstantinos Chorianopoulos; Michail Giannakos

    2014-01-01

    There is growing interest in the employment of serious video games in science education, but there are no clear design principles. After surveying previous work in serious video game design, we highlighted the following design principles: 1) engage the students with narrative (hero, story), 2) employ familiar gameplay mechanics from popular video games, 3) engage students into constructive trial and error game-play and 4) situate collaborative learning. As illustrated examples we designed two...

  6. Design principles for data- and change-oriented organisational analysis in workplace health promotion.

    Science.gov (United States)

    Inauen, A; Jenny, G J; Bauer, G F

    2012-06-01

    This article focuses on organizational analysis in workplace health promotion (WHP) projects. It shows how this analysis can be designed such that it provides rational data relevant to the further context-specific and goal-oriented planning of WHP and equally supports individual and organizational change processes implied by WHP. Design principles for organizational analysis were developed on the basis of a narrative review of the guiding principles of WHP interventions and organizational change as well as the scientific principles of data collection. Further, the practical experience of WHP consultants who routinely conduct organizational analysis was considered. This resulted in a framework with data-oriented and change-oriented design principles, addressing the following elements of organizational analysis in WHP: planning the overall procedure, data content, data-collection methods and information processing. Overall, the data-oriented design principles aim to produce valid, reliable and representative data, whereas the change-oriented design principles aim to promote motivation, coherence and a capacity for self-analysis. We expect that the simultaneous consideration of data- and change-oriented design principles for organizational analysis will strongly support the WHP process. We finally illustrate the applicability of the design principles to health promotion within a WHP case study.

  7. Some General Principles in Cryogenic Design, Implementation, and Testing

    Science.gov (United States)

    Dipirro, Michael James

    2015-01-01

    Brief Course Description: In 2 hours only the most basic principles of cryogenics can be presented. I will concentrate on the differences between a room temperature thermal analysis and cryogenic thermal analysis, namely temperature dependent properties. I will talk about practical materials for thermal contact and isolation. I will finish by describing the verification process and instrumentation used that is unique to cryogenic (in general less than 100K) systems.

  8. ANALYSIS OF FUZZY QUEUES: PARAMETRIC PROGRAMMING APPROACH BASED ON RANDOMNESS - FUZZINESS CONSISTENCY PRINCIPLE

    OpenAIRE

    Dhruba Das; Hemanta K. Baruah

    2015-01-01

    In this article, based on Zadeh’s extension principle we have apply the parametric programming approach to construct the membership functions of the performance measures when the interarrival time and the service time are fuzzy numbers based on the Baruah’s Randomness- Fuzziness Consistency Principle. The Randomness-Fuzziness Consistency Principle leads to defining a normal law of fuzziness using two different laws of randomness. In this article, two fuzzy queues FM...

  9. Food Safety Programs Based on HACCP Principles in School Nutrition Programs: Implementation Status and Factors Related to Implementation

    Science.gov (United States)

    Stinson, Wendy Bounds; Carr, Deborah; Nettles, Mary Frances; Johnson, James T.

    2011-01-01

    Purpose/Objectives: The objectives of this study were to assess the extent to which school nutrition (SN) programs have implemented food safety programs based on Hazard Analysis and Critical Control Point (HACCP) principles, as well as factors, barriers, and practices related to implementation of these programs. Methods: An online survey was…

  10. Evaluation of the revised training program for senior control room staff: science fundamentals and equipment principles

    International Nuclear Information System (INIS)

    Jervis, R.E.; Evans, G.J.

    1996-10-01

    Canadian nuclear utilities have formed an Inter-Utility Working Group to revise their program for training nuclear generating station senior control room staff, namely Control Room Operators and Shift Supervisors, in Science Fundamentals and Equipment Principles. This report documents the findings of an external review of this revision process, addressing, amongst other topics, the process of revision undertaken by the Working Group, their outline of topics to be included, and, the pertinence and comprehensiveness of the detailed training objectives identified for two of the courses. The approach to revising the program being followed by the Working Group appears to be reasonable insomuch that some training needs have been identified and used to construct detailed sets of training objectives. However, as assessed by the consultants without full documentation being available, some important steps appear to have been missed. Specifically, much of the basis of the revision process has not been documented, neither has the approach selected for the revision process, nor has any justification for not performing a CANDU specific job and task analysis been offered. Furthermore, the Working Group has not yet proposed any criteria for evaluation of the program or provided any test items. As a result, the consultants have had to develop criteria for evaluation of the overall program and of individual courses. These criteria were applied in a more detailed review of the training objectives for two particular courses: Plant Chemistry, and Nuclear Physics and Reactor Theory. Many of the training objectives for these courses were found to be too qualitative or ones that require trainees to memorize blocks of information rather than develop in them an ability to arrive at conclusions about scientific phenomena using principles and reasoning. This assessment indicates that the training objectives are designed to achieve too low a level of cognition, inconsistent with developing an

  11. Friction reduction using discrete surface textures: principle and design

    International Nuclear Information System (INIS)

    Hsu, Stephen M; Jing, Yang; Hua, Diann; Zhang, Huan

    2014-01-01

    There have been many reports on the use of dimples, grooves, and other surface textures to control friction in sliding interfaces. The effectiveness of surface textures in friction reduction has been demonstrated in conformal contacts under high speed low load applications such as mechanical seals and automotive water pump seals, etc., resulting in reduced friction and longer durability. For sliding components with higher contact pressures or lower speeds, conflicting results were reported. Reasons for the inconsistency may be due to the differences in texture fabrication techniques, lack of dimple size and shape uniformity, and different tester used. This paper examines the basic principles on which surface textural patterns influence friction under the three principle lubrication regimes: hydrodynamic, elastohydrodynamic, and boundary lubrication regimes. Our findings suggest that each regime requires specific dimple size, shape, depth, and areal density to achieve friction reduction. Control experiments were also conducted to explore mechanisms of friction reduction. The dimple geometric shape and the dimple's orientation with respect to the sliding direction influence friction significantly. The underlying mechanisms for friction control via textures are discussed. (paper)

  12. Design of a Blended Learning Environment Based on Merrill’s Principles

    Science.gov (United States)

    Simarmata, Janner; Djohar, Asari; Purba, Janulis; Juanda, Enjang A.

    2018-01-01

    Designing blended learning courses requires a systematic approach, in instructional design decisions and implementations, instructional principles help educators not only to specify the elements of the course, but also to provide a solid base from which to build the technology. The blended learning course was designed based on Merrill’s First Principles of Instruction with five phases. This paper helps inform educators about how to develop appropriate learning styles and preferences according to students’ learning needs.

  13. Media Designed Programs for Librarians.

    Science.gov (United States)

    Penland, Patrick R.

    Media materials and services may be used for two different but closely related purposes: motivating people to participate in informational and educational experiences, and motivating them to learn. As more librarians and patrons begin to use the audiovisual media they may be induced to question conventional principles of composition and work to…

  14. Design principles and fundamental trade-offs in biomimetic light harvesting

    International Nuclear Information System (INIS)

    Sarovar, Mohan; Birgitta Whaley, K

    2013-01-01

    Recent developments in synthetic and supramolecular chemistry have created opportunities to design organic systems with tailored nanoscale structure for various technological applications. A key application area is the capture of light energy and its conversion into electrochemical or chemical forms for photovoltaic or sensing applications. In this work we consider cylindrical assemblies of chromophores that model structures produced by several supramolecular techniques. Our study is especially guided by the versatile structures produced by virus-templated assembly. We use a multi-objective optimization framework to determine design principles and limitations in light harvesting performance for such assemblies, both in the presence and absence of disorder. We identify a fundamental trade-off in cylindrical assemblies that is encountered when attempting to maximize both efficiency of energy transfer and absorption bandwidth. We also rationalize the optimal design strategies and provide explanations for why various structures provide optimal performance. Most importantly, we find that the optimal design strategies depend on the amount of energetic and structural disorder in the system. The aim of these studies is to develop a program of quantum-informed rational design for construction of organic assemblies that have the same degree of tailored nanoscale structure as biological photosynthetic light harvesting complexes, and consequently have the potential to reproduce their remarkable light harvesting performance. (paper)

  15. Generative design visualize, program, and create with processing

    CERN Document Server

    Bohnacker, Hartmut; Laub, Julia; Lazzeroni, Claudius

    2012-01-01

    Generative design is a revolutionary new method of creating artwork, models, and animations from sets of rules, or algorithms. By using accessible programming languages such as Processing, artists and designers are producing extravagant, crystalline structures that can form the basis of anything from patterned textiles and typography to lighting, scientific diagrams, sculptures, films, and even fantastical buildings. Opening with a gallery of thirty-five illustrated case studies, Generative Design takes users through specific, practical instructions on how to create their own visual experiments by combining simple-to-use programming codes with basic design principles. A detailed handbook of advanced strategies provides visual artists with all the tools to achieve proficiency. Both a how-to manual and a showcase for recent work in this exciting new field, Generative Design is the definitive study and reference book that designers have been waiting for.

  16. Four Principles for User Interface Design of Computerised Clinical Decision Support Systems

    DEFF Research Database (Denmark)

    Kanstrup, Anne Marie; Christiansen, Marion Berg; Nøhr, Christian

    2011-01-01

    emphasises a focus on how users interact with the system, a focus on how information is provided by the system, and four principles of interaction. The four principles for design of user interfaces for CDSS are summarised as four A’s: All in one, At a glance, At hand and Attention. It is recommended that all...... four interaction principles are integrated in the design of user interfaces for CDSS, i.e. the model is an integrated model which we suggest as a guide for interaction design when working with preventing medication errors....

  17. Resisting Technological Gravity: Using Guiding Principles for Instructional Design

    Science.gov (United States)

    McDonald, Jason K.

    2010-01-01

    Instructional designers face tremendous pressure to abandon the essential characteristics of educational approaches, and settle instead for routine practices that do not preserve the level of quality those approaches originally expressed. Because this pressure can be strong enough to affect designers almost as gravity affects objects in the…

  18. Principles and Concepts for Information and Communication Technology Design.

    Science.gov (United States)

    Adams, Ray; Langdon, Patrick

    2003-01-01

    This article presents a theory for evaluating information and communication technology design for individuals with disabilities. Simplex 1 evaluates designs in five zones: sensory and input zone; output zone; abstract working memory; long-term memory; and central executive functioning. Simplex 2 evaluates feedback, emotional responses, cognitive…

  19. Software tools to aid Pascal and Ada program design

    Energy Technology Data Exchange (ETDEWEB)

    Jankowitz, H.T.

    1987-01-01

    This thesis describes a software tool which analyses the style and structure of Pascal and Ada programs by ensuring that some minimum design requirements are fulfilled. The tool is used in much the same way as a compiler is used to teach students the syntax of a language, only in this case issues related to the design and structure of the program are of paramount importance. The tool operates by analyzing the design and structure of a syntactically correct program, automatically generating a report detailing changes that need to be made in order to ensure that the program is structurally sound. The author discusses how the model gradually evolved from a plagiarism detection system which extracted several measurable characteristics in a program to a model that analyzed the style of Pascal programs. In order to incorporate more-sophistical concepts like data abstraction, information hiding and data protection, this model was then extended to analyze the composition of Ada programs. The Ada model takes full advantage of facilities offered in the language and by using this tool the standard and quality of written programs is raised whilst the fundamental principles of program design are grasped through a process of self-tuition.

  20. Using principles of learning to inform language therapy design for children with specific language impairment.

    Science.gov (United States)

    Alt, Mary; Meyers, Christina; Ancharski, Alexandra

    2012-01-01

    Language treatment for children with specific language impairment (SLI) often takes months to achieve moderate results. Interventions often do not incorporate the principles that are known to affect learning in unimpaired learners. To outline some key findings about learning in typical populations and to suggest a model of how they might be applied to language treatment design as a catalyst for further research and discussion. Three main principles of implicit learning are reviewed: variability, complexity and sleep-dependent consolidation. After explaining these principles, evidence is provided as to how they influence learning tasks in unimpaired learners. Information is reviewed on principles of learning as they apply to impaired populations, current treatment designs are also reviewed that conform to the principles, and ways in which principles of learning might be incorporated into language treatment design are demonstrated. This paper provides an outline for how theoretical knowledge might be applied to clinical practice in an effort to promote discussion. Although the authors look forward to more specific details on how the principles of learning relate to impaired populations, there is ample evidence to suggest that these principles should be considered during treatment design. © 2012 Royal College of Speech and Language Therapists.

  1. The principle of commonality and its application to the Space Station Freedom Program

    Science.gov (United States)

    Hopson, George D.; Thomas, L. Dale; Daniel, Charles C.

    1989-01-01

    The principle of commonality has achieved wide application in the communication, automotive, and aircraft industries. By the use of commonality, component development costs are minimized, logistics are simplified, and the investment costs of spares inventory are reduced. With space systems, which must be maintained and repaired in orbit, the advantages of commonality are compounded. Transportation of spares is expensive, on-board storage volume for spares is limited, and crew training and special tools needed for maintenance and repair are significant considerations. This paper addresses the techniques being formulated to realize the benefits of commonality in the design of the systems and elements of the Space Station Freedom Program, and include the criteria for determining the extent of commonality to be implemented.

  2. Design Principles and Concepts for Enhancing Long-Term Cap Performance and Confidence

    International Nuclear Information System (INIS)

    Steven J. Piet; Robert P. Breckenridge; Gregory J. White; Jacob J. Jacobson; Hilary I. Inyang

    2005-01-01

    The siting of new landfills is becoming increasing difficult as the public and stakeholders want more confidence of performance for longer times and landfill owners want to store more waste in the least area while knowing and limiting their long-term liabilities. These changes motivate re-examination of long-term performance mechanisms and their implications for cap and barrier designs. Accordingly, in this paper we first consider design principles from the standpoint of long-term performance and management, including the ability to monitor and repair barriers. We then consider some design concepts that may implement these principles, especially evapo-transpiration (ET) caps. We suggest five design principles based on experience in the cap and barrier field as well as other engineering disciplines. These principles are as follows: (1) Establish a clear and defendable design basis. (2) Design for ease of monitoring and repair. (3) Analyze the barrier as a dynamic system, not static. (4) Work with nature, not against. (5) Recognize that increased complexity can reduce, not enhance, net performance. ET caps are an excellent embodiment of these design principles. We apply the design principles to ET caps, as well as variants such as erosion armor, capillary breaks, bio-intrusion layers, and low permeability material layers

  3. Market Aspects of an Interior Design Program.

    Science.gov (United States)

    Gold, Judy E.

    A project was conducted to evaluate a proposed interior design program in order to determine the marketability (job availability in the field of interior design and home furnishings merchandising) and the feasibility (educational requirements for entrance into the interior design and home furnishings merchandising job market) of the program. To…

  4. 49 CFR Appendix E to Part 238 - General Principles of Reliability-Based Maintenance Programs

    Science.gov (United States)

    2010-10-01

    ... STANDARDS Pt. 238, App. E Appendix E to Part 238—General Principles of Reliability-Based Maintenance... 49 Transportation 4 2010-10-01 2010-10-01 false General Principles of Reliability-Based... the design level of safety and reliability of the equipment; (2) To restore safety and reliability to...

  5. Principles of VLSI RTL design a practical guide

    CERN Document Server

    Churiwala, Sanjay; Gianfagna, Mike

    2011-01-01

    This book examines the impact of register transfer level (RTL) design choices that may result in issues of testability, data synchronization across clock domains, synthesizability, power consumption and routability, that appear later in the product lifecycle.

  6. SOA and Web services interface design principles, techniques, and standards

    CERN Document Server

    Bean, James

    2009-01-01

    SOA offers solutions to the most intractable business problems faced by every enterprise, but getting the SOA service interface right requires the practical design knowledge this book uniquely delivers

  7. Constructal Law and the Unifying Principle of Design

    CERN Document Server

    Lorente, Sylvie; Bejan, Adrian

    2013-01-01

    Design happens everywhere, whether in animate objects (e.g., dendritic lung structures, bacterial colonies, and corals), inanimate patterns (river basins, beach slope, and dendritic crystals), social dynamics (pedestrian traffic flows), or engineered systems (heat dissipation in electronic circuitry). This “design in nature” often takes on remarkably similar patterns, which can be explained under one unifying Constructal Law. This book explores the unifying power of the Constructal Law and its applications in all domains of design generation and evolution, ranging from biology and geophysics to globalization, energy, sustainability, and security.  The Constructal Law accounts for the universal tendency of flow systems to morph into evolving configurations that provide greater and easier access over time. The Constructal Law resolves the many and contradictory ad hoc statements of “optimality”, end design, and destiny in nature, such as minimum and maximum entropy production and minimum and maximum fl...

  8. Sales Course Design Using Experiential Learning Principles and Bloom's Taxonomy

    Science.gov (United States)

    Healy, William J.; Taran, Zinaida; Betts, Stephen C.

    2011-01-01

    Practitioner concerns and the changing educational marketplace are pressuring colleges to provide more skills based learning. Among the newer skill based areas of study that is greatly in demand is professional sales. In this paper, two courses in a successful professional sales program are examined through the lenses of experiential learning…

  9. A Learning and Interaction design framework, from a study on formulating principles for the design of engaging music learning games

    DEFF Research Database (Denmark)

    Weitze, Charlotte Lærke; Ørngreen, Rikke

    2012-01-01

    Based on a preliminary action research study investigating the design of digital music games and years of experiences from interaction design processes of learning resources, this extended abstract presents a framework that mixes designs for learning principles and game design with a process view...... using a simple interaction design lifecycle. Though the first outset was to design engaging music games, the resulting framework has a more generic character....

  10. Structured Design Language for Computer Programs

    Science.gov (United States)

    Pace, Walter H., Jr.

    1986-01-01

    Box language used at all stages of program development. Developed to provide improved productivity in designing, coding, and maintaining computer programs. BOX system written in FORTRAN 77 for batch execution.

  11. Designing high pressure containers for research- principles and applications

    International Nuclear Information System (INIS)

    Anandkumar, V.

    1997-01-01

    The high pressure scientist looks for a well engineered pressure apparatus for high pressure experiments for 1 kbar (0.1 GPa) and above. Often, a variety of difficulties including the choice of materials, design configuration, optimum utilisation of the strength of materials used in the design, are encountered. This article is intended to help the high pressure scientist to select the design approach for pressure retaining container. The limitations imposed by the strength of available materials and engineering standards in building high pressure containers are discussed. Engineering solutions to overcome these limitations with optimal utilisation of the strength of the materials are also discussed. Novel methods to boost up the pressure retaining capacity like multilayered design and autofrettaging are compared along with their relative advantages and disadvantages. Special methods by which it is possible to attain pressures which are several times the yield strength of the materials of construction are presented. In this aspects such as the basis of the codes and their relevance in the design of high pressure equipment will also be described. Discussions are centered around the methods to tackle situations where experimental constraints dictate requirements of pressures higher than those permitted by design codes. Safety features are also discussed. (author)

  12. Fundamental Design Principles for Transcription-Factor-Based Metabolite Biosensors.

    Science.gov (United States)

    Mannan, Ahmad A; Liu, Di; Zhang, Fuzhong; Oyarzún, Diego A

    2017-10-20

    Metabolite biosensors are central to current efforts toward precision engineering of metabolism. Although most research has focused on building new biosensors, their tunability remains poorly understood and is fundamental for their broad applicability. Here we asked how genetic modifications shape the dose-response curve of biosensors based on metabolite-responsive transcription factors. Using the lac system in Escherichia coli as a model system, we built promoter libraries with variable operator sites that reveal interdependencies between biosensor dynamic range and response threshold. We developed a phenomenological theory to quantify such design constraints in biosensors with various architectures and tunable parameters. Our theory reveals a maximal achievable dynamic range and exposes tunable parameters for orthogonal control of dynamic range and response threshold. Our work sheds light on fundamental limits of synthetic biology designs and provides quantitative guidelines for biosensor design in applications such as dynamic pathway control, strain optimization, and real-time monitoring of metabolism.

  13. Design principles and realization of electro-optical circuit boards

    Science.gov (United States)

    Betschon, Felix; Lamprecht, Tobias; Halter, Markus; Beyer, Stefan; Peterson, Harry

    2013-02-01

    The manufacturing of electro-optical circuit boards (EOCB) is based to a large extent on established technologies. First products with embedded polymer waveguides are currently produced in series. The range of applications within the sensor and data communication markets is growing with the increasing maturity level. EOCBs require design flows, processes and techniques similar to existing printed circuit board (PCB) manufacturing and appropriate for optical signal transmission. A key aspect is the precise and automated assembly of active and passive optical components to the optical waveguides which has to be supported by the technology. The design flow is described after a short introduction into the build-up of EOCBs and the motivation for the usage of this technology within the different application fields. Basis for the design of EOCBs are the required optical signal transmission properties. Thereafter, the devices for the electro-optical conversion are chosen and the optical coupling approach is defined. Then, the planar optical elements (waveguides, splitters, couplers) are designed and simulated. This phase already requires co-design of the optical and electrical domain using novel design flows. The actual integration of an optical system into a PCB is shown in the last part. The optical layer is thereby laminated to the purely electrical PCB using a conventional PCB-lamination process to form the EOCB. The precise alignment of the various electrical and optical layers is thereby essential. Electrical vias are then generated, penetrating also the optical layer, to connect the individual electrical layers. Finally, the board has to be tested electrically and optically.

  14. Computers as Components Principles of Embedded Computing System Design

    CERN Document Server

    Wolf, Wayne

    2008-01-01

    This book was the first to bring essential knowledge on embedded systems technology and techniques under a single cover. This second edition has been updated to the state-of-the-art by reworking and expanding performance analysis with more examples and exercises, and coverage of electronic systems now focuses on the latest applications. Researchers, students, and savvy professionals schooled in hardware or software design, will value Wayne Wolf's integrated engineering design approach.The second edition gives a more comprehensive view of multiprocessors including VLIW and superscalar archite

  15. Design principles of a nuclear and industrial HVAC of IFMIF

    International Nuclear Information System (INIS)

    Pruneri, Giuseppe; Ibarra, A.; Heidinger, R.; Knaster, J.; Sugimoto, M.

    2016-01-01

    Highlights: • Parameter of Derivate air Contamination (DAC) allows to associate the type of air ventilation. • The construction and operation of IFMIF will be subjected to the regulations of the country in which it will be sited. • Structures, systems and components are assigned a particular safety important components (SIC, 1–2 and Non-SIC) clarification that is based on the consequences of their failure. • Reliability, Availability, Maintainability and Inspectability (RAMI) analysis has given a great contribution of the facility to optimize the configuration, particularly for the HVAC system. - Abstract: In 2013, the IFMIF, the International Fusion Material Irradiation Facility, presently in its Engineering Validation and Engineering Design Activities (EVEDA) phase, framed by the Broader Approach Agreement between Japan and EURATOM, accomplished in 2013 its mandate to provide the engineering design of the plant on schedule [1]. The IFMIF aims to qualify and characterize materials that are capable of withstanding the intense neutron flux originated in D-T reactions of future fusion reactors due to a neutron flux with a broad peak at 14 MeV, which is able to provide >20 dpa/fpy on small specimens in this EVEDA phase. The successful operation of such a challenging plant demands a careful assessment of the Conventional Facilities (CF), which have adequate redundancies to allow for the target plant availability [2]. The present paper addresses the design proposed in the IFMIF Intermediate Engineering Design Report regarding the CF, particularly the IFMIF's Nuclear and Industrial HVAC design. A preliminary feasibility study, including the initial configuration, calculations and reliability/availability analysis, were performed. The nuclear HVAC design was developed progressively; first, by establishing a conceptual design, starting from the system functional description, followed by the identification of the corresponding interfacing systems and their

  16. Design principles of a nuclear and industrial HVAC of IFMIF

    Energy Technology Data Exchange (ETDEWEB)

    Pruneri, Giuseppe [IFMIF/EVEDA, Project Team, Rokkasho (Japan); Ibarra, A. [CIEMAT, Madrid (Spain); Heidinger, R. [F4E, Garching (Germany); Knaster, J. [IFMIF/EVEDA Project Team, Rokkasho (Japan); Sugimoto, M. [JAEA, Rokkasho (Japan)

    2016-02-15

    Highlights: • Parameter of Derivate air Contamination (DAC) allows to associate the type of air ventilation. • The construction and operation of IFMIF will be subjected to the regulations of the country in which it will be sited. • Structures, systems and components are assigned a particular safety important components (SIC, 1–2 and Non-SIC) clarification that is based on the consequences of their failure. • Reliability, Availability, Maintainability and Inspectability (RAMI) analysis has given a great contribution of the facility to optimize the configuration, particularly for the HVAC system. - Abstract: In 2013, the IFMIF, the International Fusion Material Irradiation Facility, presently in its Engineering Validation and Engineering Design Activities (EVEDA) phase, framed by the Broader Approach Agreement between Japan and EURATOM, accomplished in 2013 its mandate to provide the engineering design of the plant on schedule [1]. The IFMIF aims to qualify and characterize materials that are capable of withstanding the intense neutron flux originated in D-T reactions of future fusion reactors due to a neutron flux with a broad peak at 14 MeV, which is able to provide >20 dpa/fpy on small specimens in this EVEDA phase. The successful operation of such a challenging plant demands a careful assessment of the Conventional Facilities (CF), which have adequate redundancies to allow for the target plant availability [2]. The present paper addresses the design proposed in the IFMIF Intermediate Engineering Design Report regarding the CF, particularly the IFMIF's Nuclear and Industrial HVAC design. A preliminary feasibility study, including the initial configuration, calculations and reliability/availability analysis, were performed. The nuclear HVAC design was developed progressively; first, by establishing a conceptual design, starting from the system functional description, followed by the identification of the corresponding interfacing systems and their

  17. Verification of Concurrent Programs. Part II. Temporal Proof Principles.

    Science.gov (United States)

    1981-09-01

    not modify any of the shared program variables. In order to ensure the correct synchronization between the processes we use three semaphore variables...direct, simple, and intuitive rides for the establishment of these properties. rhey usually replace long but repetitively similar chains of primitive ...modify the variables on which Q actually depends. A typical case is that of semaphores . We have the following property: The Semaphore Variable Rule

  18. Execution Of Systems Integration Principles During Systems Engineering Design

    Science.gov (United States)

    2016-09-01

    application utilized a paper-based approach to systems design. The customer directed utilization of an SE Waterfall process model . These new...regarding requirements, stakeholders, testing, and system boundaries. Additionally, this thesis discusses use of systems architecture frameworks and models ...and the consistent use of model - based systems engineering throughout development. Lastly, it proposes formal methods language for improving models

  19. Design Principles for Digital Badges Used in Libraries

    Science.gov (United States)

    Rimland, Emily; Raish, Victoria

    2017-01-01

    Digital badges give libraries greater flexibility in delivering impactful instruction to students. They serve as flexible, stackable microcredentials that sequence an information literacy experience across the curriculum. Design considerations rooted in learning theory have a foundation through which to drive decisions. Information literacy badges…

  20. Designing sustainable energy landscapes : concepts, principles and procedures

    NARCIS (Netherlands)

    Stremke, S.

    2010-01-01

    The depletion of fossil fuels, in combination with climate change, necessitates a transition to sustainable energy systems. Such systems are characterized by a decreased energy demand and an increase in the use of renewables. The objective of this dissertation is to advance the planning and design

  1. PHASAR-based WDM-devices: principles, design and applications

    NARCIS (Netherlands)

    Smit, M.K.; Dam, van C.

    1996-01-01

    Wavelength multiplexers, demultiplexers and routers based on optical phased arrays play a key role in multiwavelength telecommunication links and networks. In this paper, a detailed description of phased-array operation and design is presented and an overview is given of the most important

  2. Mammalian designer cells: Engineering principles and biomedical applications.

    Science.gov (United States)

    Xie, Mingqi; Fussenegger, Martin

    2015-07-01

    Biotechnology is a widely interdisciplinary field focusing on the use of living cells or organisms to solve established problems in medicine, food production and agriculture. Synthetic biology, the science of engineering complex biological systems that do not exist in nature, continues to provide the biotechnology industry with tools, technologies and intellectual property leading to improved cellular performance. One key aspect of synthetic biology is the engineering of deliberately reprogrammed designer cells whose behavior can be controlled over time and space. This review discusses the most commonly used techniques to engineer mammalian designer cells; while control elements acting on the transcriptional and translational levels of target gene expression determine the kinetic and dynamic profiles, coupling them to a variety of extracellular stimuli permits their remote control with user-defined trigger signals. Designer mammalian cells with novel or improved biological functions not only directly improve the production efficiency during biopharmaceutical manufacturing but also open the door for cell-based treatment strategies in molecular and translational medicine. In the future, the rational combination of multiple sets of designer cells could permit the construction and regulation of higher-order systems with increased complexity, thereby enabling the molecular reprogramming of tissues, organisms or even populations with highest precision. Copyright © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. Public Relations for Brazilian Libraries: Process, Principles, Program Planning, Planning Techniques and Suggestions.

    Science.gov (United States)

    Kies, Cosette N.

    A brief overview of the functions of public relations in libraries introduces this manual, which provides an explanation of the public relations (PR) process, including fact-finding, planning, communicating, evaluating, and marketing; some PR principles; a 10-step program that could serve as a model for planning a PR program; a discussion of PR…

  4. Serious game design principles: The impact of game design on learning outcomes

    Science.gov (United States)

    Martin, Michael W.

    This dissertation examines the research question "How do video game design principles affect learning outcomes in serious games?" This research first develops a theoretical foundation concerning the meaning of the terms "game" and "serious game". This conceptual clarification is broken down into analytic propositions, which state that games have participants, rules, goals and challenges, and synthetic propositions, which state that the games should be intrinsically compelling, provide meaningful choices, and be self encapsulated. Based on these synthetic propositions, three hypotheses were developed. The hypotheses are that games with an enhanced aesthetic presentation, more meaningful choices, or provide player competition will elicit higher learning outcomes than identical games without these factors. These hypotheses were tested via a quantitative experiment involving 172 undergraduate students in the Old Dominion University Chemistry Department. The students were asked to play a chemistry-oriented serious game entitled Element Solitaire©, which was created by the research author. The students were randomly given different treatments of the Element Solitaire© game to play, and the difference between their learning outcomes were compared. The experimental results demonstrated that the aesthetic presentation of a game can have a significant impact upon the learning outcome. The experiment was not able to discern significant effects from the choice or competition conditions, but further examination of the experimental data did reveal some insight into these aspects of serious game design. Choices need to provide the player with options that have a sufficient value that they will be considered and the application of competition within games needs to be judiciously implemented to promote a positive affect for all players. The results of the theoretical foundations and empirical evidence were then combined with additional theoretical research to develop a set of

  5. Emergent features and perceptual objects: re-examining fundamental principles in analogical display design.

    Science.gov (United States)

    Holt, Jerred; Bennett, Kevin B; Flach, John M

    2015-01-01

    Two sets of design principles for analogical visual displays, based on the concepts of emergent features and perceptual objects, are described. An interpretation of previous empirical findings for three displays (bar graph, polar graphic, alphanumeric) is provided from both perspectives. A fourth display (configural coordinate) was designed using principles of ecological interface design (i.e. direct perception). An experiment was conducted to evaluate performance (accuracy and latency of state identification) with these four displays. Numerous significant effects were obtained and a clear rank ordering of performance emerged (from best to worst): configural coordinate, bar graph, alphanumeric and polar graphic. These findings are consistent with principles of design based on emergent features; they are inconsistent with principles based on perceptual objects. Some limitations of the configural coordinate display are discussed and a redesign is provided. Practitioner Summary: Principles of ecological interface design, which emphasise the quality of very specific mappings between domain, display and observer constraints, are described; these principles are applicable to the design of all analogical graphical displays.

  6. Network-driven design principles for neuromorphic systems

    OpenAIRE

    Partzsch, Johannes; Sch?ffny, Rene

    2015-01-01

    Synaptic connectivity is typically the most resource-demanding part of neuromorphic systems. Commonly, the architecture of these systems is chosen mainly on technical considerations. As a consequence, the potential for optimization arising from the inherent constraints of connectivity models is left unused. In this article, we develop an alternative, network-driven approach to neuromorphic architecture design. We describe methods to analyse performance of existing neuromorphic architectures i...

  7. Designing sensory-substitution devices: Principles, pitfalls and potential1.

    Science.gov (United States)

    Kristjánsson, Árni; Moldoveanu, Alin; Jóhannesson, Ómar I; Balan, Oana; Spagnol, Simone; Valgeirsdóttir, Vigdís Vala; Unnthorsson, Rúnar

    2016-09-21

    An exciting possibility for compensating for loss of sensory function is to augment deficient senses by conveying missing information through an intact sense. Here we present an overview of techniques that have been developed for sensory substitution (SS) for the blind, through both touch and audition, with special emphasis on the importance of training for the use of such devices, while highlighting potential pitfalls in their design. One example of a pitfall is how conveying extra information about the environment risks sensory overload. Related to this, the limits of attentional capacity make it important to focus on key information and avoid redundancies. Also, differences in processing characteristics and bandwidth between sensory systems severely constrain the information that can be conveyed. Furthermore, perception is a continuous process and does not involve a snapshot of the environment. Design of sensory substitution devices therefore requires assessment of the nature of spatiotemporal continuity for the different senses. Basic psychophysical and neuroscientific research into representations of the environment and the most effective ways of conveying information should lead to better design of sensory substitution systems. Sensory substitution devices should emphasize usability, and should not interfere with other inter- or intramodal perceptual function. Devices should be task-focused since in many cases it may be impractical to convey too many aspects of the environment. Evidence for multisensory integration in the representation of the environment suggests that researchers should not limit themselves to a single modality in their design. Finally, we recommend active training on devices, especially since it allows for externalization, where proximal sensory stimulation is attributed to a distinct exterior object.

  8. Computing risk for oil prospects: principles and programs

    International Nuclear Information System (INIS)

    Harbaugh, J.W.; Davis, J.C.; Wendebourg, J.

    1995-01-01

    This volume in the series Computer Methods in the Geosciences examines the challenge of risk assessment, field size distributions, and success, sequence and gambler's ruin. The estimation of the discovery size from the prospect size, outcome probabilities and success ratios, modeling prospects, and mapping properties and uncertainties are reviewed, and discriminating discoveries and dry holes, forecasting cash flow for a prospect, the worth of money, and use of risk analysis tables, decision tables and trees are considered. Appendices cover the installation of the RISK program and user manuals, and two disks are included with the volume. (UK)

  9. Network-driven design principles for neuromorphic systems

    Directory of Open Access Journals (Sweden)

    Johannes ePartzsch

    2015-10-01

    Full Text Available Synaptic connectivity is typically the most resource-demanding part of neuromorphic systems. Commonly, the architecture of these systems is chosen mainly on technical considerations. As a consequence, the potential for optimization arising from the inherent constraints of connectivity models is left unused. In this article, we develop an alternative, network-driven approach to neuromorphic architecture design. We describe methods to analyse performance of existing neuromorphic architectures in emulating certain connectivity models. Furthermore, we show step-by-step how to derive a neuromorphic architecture from a given connectivity model. For this, we introduce a generalized description for architectures with a synapse matrix, which takes into account shared use of circuit components for reducing total silicon area. Architectures designed with this approach are fitted to a connectivity model, essentially adapting to its connection density. They are guaranteeing faithful reproduction of the model on chip, while requiring less total silicon area. In total, our methods allow designers to implement more area-efficient neuromorphic systems and verify usability of the connectivity resources in these systems.

  10. Network-driven design principles for neuromorphic systems.

    Science.gov (United States)

    Partzsch, Johannes; Schüffny, Rene

    2015-01-01

    Synaptic connectivity is typically the most resource-demanding part of neuromorphic systems. Commonly, the architecture of these systems is chosen mainly on technical considerations. As a consequence, the potential for optimization arising from the inherent constraints of connectivity models is left unused. In this article, we develop an alternative, network-driven approach to neuromorphic architecture design. We describe methods to analyse performance of existing neuromorphic architectures in emulating certain connectivity models. Furthermore, we show step-by-step how to derive a neuromorphic architecture from a given connectivity model. For this, we introduce a generalized description for architectures with a synapse matrix, which takes into account shared use of circuit components for reducing total silicon area. Architectures designed with this approach are fitted to a connectivity model, essentially adapting to its connection density. They are guaranteeing faithful reproduction of the model on chip, while requiring less total silicon area. In total, our methods allow designers to implement more area-efficient neuromorphic systems and verify usability of the connectivity resources in these systems.

  11. [Structured residency training program for otolaryngology: a trendsetting principle].

    Science.gov (United States)

    Meyer, J E; Wollenberg, B; Schmidt, C

    2008-09-01

    A concept for an ORL residency training program is necessary because of personnel bottlenecks, quality assurance and benchmarkings. We have created a 2.5 years' program, which is based on 6 pillars: 1. Acquisition of the necessary specialist knowledge by the resident in self-study. 2. Weekly attendance of training lectures according to a study timetable, a monthly specialist seminar to discuss case examples. 3. Weekly presentation by the resident on an article from the current literature, alternating with a presentation on cases and a morbidity and mortality conference. 4. Annual 60 min learning target test. 5. Definition of a surgical training calendar oriented to the new national ORL training regulations. 6. Internal operation course with preparative exercises in anatomy and visit to an operations course at a renowned otolaryngology clinic each year. After 2.5 years of the training time a revision course is introduced. In this way a basic training will be guaranteed for all residents, which can be assessed by the annual test. Finally, the construction of a further training curriculum should lead to an improved transparent training, a higher standard of quality and improved staff satisfaction.

  12. Business Education for Plastic Surgeons: A Systematic Review, Development, and Implementation of a Business Principles Curriculum in a Residency Program.

    Science.gov (United States)

    Zarrabi, Bahar; Burce, Karen K; Seal, Stella M; Lifchez, Scott D; Redett, Richard J; Frick, Kevin D; Dorafshar, Amir H; Cooney, Carisa M

    2017-05-01

    Rising health care costs, decreasing reimbursement rates, and changes in American health care are forcing physicians to become increasingly business-minded. Both academic and private plastic surgeons can benefit from being educated in business principles. The authors conducted a systematic review to identify existing business curricula and integrated a business principles curriculum into residency training. The authors anonymously surveyed their department regarding perceived importance of business principles and performed a systematic literature review from 1993 to 2013 using PubMed and Embase to identify residency training programs that had designed/implemented business curricula. Subsequently, the authors implemented a formal, quarterly business curriculum. Thirty-two of 36 physicians (88.9 percent; 76.6 percent response rate) stated business principles are either "pretty important" or "very important" to being a doctor. Only 36 percent of faculty and 41 percent of trainees had previous business instruction. The authors identified 434 articles in the systematic review: 29 documented formal business curricula. Twelve topics were addressed, with practice management/administration (n = 22) and systems-based practice (n = 6) being the most common. Four articles were from surgical specialties: otolaryngology (n = 1), general surgery (n = 2), and combined general surgery/plastic surgery (n = 1). Teaching formats included lectures and self-directed learning modules; outcomes and participant satisfaction were reported inconsistently. From August of 2013 to June of 2015, the authors held eight business principles sessions. Postsession surveys demonstrated moderately to extremely satisfied responses in 75 percent or more of resident/fellow respondents (n = 13; response rate, 48.1 percent) and faculty (n = 9; response rate, 45.0 percent). Business principles can be integrated into residency training programs. Having speakers familiar with the physician audience and a

  13. Beam dynamics pre-design with KONUS principle for the DTL of SPPC p-Linac

    Science.gov (United States)

    Liu, Jing; Li, Haipeng; Lu, Yuanrong; Su, Jiancang; Liu, Xiaolong; Fu, Qi

    2018-04-01

    As the Higgs bosons were observed on the LHC in 2012, a two-stage particle collider program named CEPC-SPPC is proposed for precise measurement of Higgs properties and exploring the new physics models. In order to deliver a 2.1-TeV proton beam into the Super Proton-Proton Collider (SPPC), the injector chain will use a 1.2-GeV proton linac (p-Linac) and three synchrotrons of p-RCS, MSS and SS. This paper focuses on the preliminary conceptual design of the DTL within the p-Linac and mainly concerns about the beam dynamics studies. Taking advantages of the KONUS principle and LORASR code, a 325 MHz, 50.65 MeV DTL design which is composed of three tanks in 15.6 m will be presented. The whole DTL contains 129 gaps for beam acceleration, one quadruple doublet which is behind the buncher and eight quadruple triplets of which three are located after each tank, respectively. The aims of this pre-study are to optimize the acceleration electric field distribution together with the focusing magnetic field parameters, enhance the beam transmission quality of beam envelopes, particle distribution and energy spread, then improve the DTL performance in terms of transmission efficiency and so on. The results of the analyses show that the DTL pre-design achieves 16.8 times high energy gain and meets all the p-Linac requirements well.

  14. Principles of alloy design in high nitrogen 12% chromium steels

    International Nuclear Information System (INIS)

    Goecmen, A.; Ernst, P.; Holmes, P.

    1999-01-01

    12% chromium steels are hardened by a martensitic transformation and by precipitation reactions of the martensite during a subsequent tempering treatment. The original alloy design of these steels is based on the intensifying effect of C on the martensitic transformation hardening as well as on the effects of V and Mo on intensity and stability of carbide precipitation hardening reactions. Advanced alloy design of high carbon 12% chromium steels makes use of f.c.c.-MX type carbonitrides to improve grain refinement and tempering resistance, whereas alloying with about 0.05 wt.-% nitrogen already plays a decisive role. In this paper, new alloy design opportunities provided by high nitrogen are reviewed, which promise to achieve a best possible compromise between grain size limitation, particle hardening and particle stability of 12% chromium steels. The crucial effects of the solubility product of MX-type phases on grain coarsening resistance, precipitation hardening and particle stability are reviewed. The advantages of high nitrogen steels to improve these properties are rationalized to result from the lower solubility of nitrides compared with carbides. As an advantageous opportunity of the achievable higher grain coarsening resistance, the normalizing temperature in high nitrogen steels can be increased in order to increase the amount of the less soluble and thereby slow coarsening f.c.c.-nitrides. In addition, as a consequence of a higher normalizing temperature, the solubility gap of nitrides in the austenite is expanded, which in turn enables an effective precipitation hardening due to low soluble nitrides in the metastable austenite before the martensitic transformation

  15. Real-time embedded systems design principles and engineering practices

    CERN Document Server

    Fan, Xiaocong

    2015-01-01

    This book integrates new ideas and topics from real time systems, embedded systems, and software engineering to give a complete picture of the whole process of developing software for real-time embedded applications. You will not only gain a thorough understanding of concepts related to microprocessors, interrupts, and system boot process, appreciating the importance of real-time modeling and scheduling, but you will also learn software engineering practices such as model documentation, model analysis, design patterns, and standard conformance. This book is split into four parts to help you

  16. Designing Embedded Systems with PIC Microcontrollers Principles and Applications

    CERN Document Server

    Wilmshurst, Tim

    2009-01-01

    PIC microcontrollers are used worldwide in commercial and industrial devices. The 8-bit PIC which this book focuses on is a versatile work horse that completes many designs. An engineer working with applications that include a microcontroller will no doubt come across the PIC sooner rather than later. It is a must to have a working knowledge of this 8-bit technology. This book takes the novice from introduction of embedded systems through to advanced development techniques for utilizing and optimizing the PIC family of microcontrollers in your device. To truly understand the PIC, assembly and

  17. Primate Anatomy, Kinematics, and Principles for Humanoid Design

    Science.gov (United States)

    Ambrose, Robert O.; Ambrose, Catherine G.

    2004-01-01

    The primate order of animals is investigated for clues in the design of Humanoid Robots. The pursuit is directed with a theory that kinematics, musculature, perception, and cognition can be optimized for specific tasks by varying the proportions of limbs, and in particular, the points of branching in kinematic trees such as the primate skeleton. Called the Bifurcated Chain Hypothesis, the theory is that the branching proportions found in humans may be superior to other animals and primates for the tasks of dexterous manipulation and other human specialties. The primate taxa are defined, contemporary primate evolution hypotheses are critiqued, and variations within the order are noted. The kinematic branching points of the torso, limbs and fingers are studied for differences in proportions across the order, and associated with family and genus capabilities and behaviors. The human configuration of a long waist, long neck, and short arms is graded using a kinematic workspace analysis and a set of design axioms for mobile manipulation robots. It scores well. The re emergence of the human waist, seen in early Prosimians and Monkeys for arboreal balance, but lost in the terrestrial Pongidae, is postulated as benefiting human dexterity. The human combination of an articulated waist and neck will be shown to enable the use of smaller arms, achieving greater regions of workspace dexterity than the larger limbs of Gorillas and other Hominoidea.

  18. General-purpose RFQ design program

    International Nuclear Information System (INIS)

    Wadlinger, E.A.

    1984-01-01

    We have written a general-purpose, radio-frequency quadrupole (RFQ) design program that allows maximum flexibility in picking design algorithms. This program optimizes the RFQ on any combination of design parameters while simultaneously satisfying mutually compatible, physically required constraint equations. It can be very useful for deriving various scaling laws for RFQs. This program has a friendly user interface in addition to checking the consistency of the user-defined requirements and is written to minimize the effort needed to incorporate additional constraint equations. We describe the program and present some examples

  19. Design principles of the yeast G1/S switch.

    Directory of Open Access Journals (Sweden)

    Xiaojing Yang

    2013-10-01

    Full Text Available A hallmark of the G1/S transition in budding yeast cell cycle is the proteolytic degradation of the B-type cyclin-Cdk stoichiometric inhibitor Sic1. Deleting SIC1 or altering Sic1 degradation dynamics increases genomic instability. Certain key facts about the parts of the G1/S circuitry are established: phosphorylation of Sic1 on multiple sites is necessary for its destruction, and both the upstream kinase Cln1/2-Cdk1 and the downstream kinase Clb5/6-Cdk1 can phosphorylate Sic1 in vitro with varied specificity, cooperativity, and processivity. However, how the system works as a whole is still controversial due to discrepancies between in vitro, in vivo, and theoretical studies. Here, by monitoring Sic1 destruction in real time in individual cells under various perturbations to the system, we provide a clear picture of how the circuitry functions as a switch in vivo. We show that Cln1/2-Cdk1 sets the proper timing of Sic1 destruction, but does not contribute to its destruction speed; thus, it acts only as a trigger. Sic1's inhibition target Clb5/6-Cdk1 controls the speed of Sic1 destruction through a double-negative feedback loop, ensuring a robust all-or-none transition for Clb5/6-Cdk1 activity. Furthermore, we demonstrate that the degradation of a single-phosphosite mutant of Sic1 is rapid and switch-like, just as the wild-type form. Our mathematical model confirms our understanding of the circuit and demonstrates that the substrate sharing between the two kinases is not a redundancy but a part of the design to overcome the trade-off between the timing and sharpness of Sic1 degradation. Our study provides direct mechanistic insight into the design features underlying the yeast G1/S switch.

  20. Integrating the Principles of Effective Intervention into Batterer Intervention Programming: The Case for Moving Toward More Evidence-Based Programming.

    Science.gov (United States)

    Radatz, Dana L; Wright, Emily M

    2016-01-01

    The majority of batterer intervention program (BIP) evaluations have indicated they are marginally effective in reducing domestic violence recidivism. Meanwhile, correctional programs used to treat a variety of offenders (e.g., substance users, violent offenders, and so forth) that adhere to the "principles of effective intervention" (PEI) have reported significant reductions in recidivism. This article introduces the PEI-the principles on which evidence-based practices in correctional rehabilitation are based-and identifies the degree to which they are currently integrated into BIPs. The case is made that batterer programs could be more effective if they incorporate the PEI. Recommendations for further integration of the principles into BIPs are also provided. © The Author(s) 2015.

  1. MiTEP's Collaborative Field Course Design Process Based on Earth Science Literacy Principles

    Science.gov (United States)

    Engelmann, C. A.; Rose, W. I.; Huntoon, J. E.; Klawiter, M. F.; Hungwe, K.

    2010-12-01

    Michigan Technological University has developed a collaborative process for designing summer field courses for teachers as part of their National Science Foundation funded Math Science Partnership program, called the Michigan Teacher Excellence Program (MiTEP). This design process was implemented and then piloted during two two-week courses: Earth Science Institute I (ESI I) and Earth Science Institute II (ESI II). Participants consisted of a small group of Michigan urban science teachers who are members of the MiTEP program. The Earth Science Literacy Principles (ESLP) served as the framework for course design in conjunction with input from participating MiTEP teachers as well as research done on common teacher and student misconceptions in Earth Science. Research on the Earth Science misconception component, aligned to the ESLP, is more fully addressed in GSA Abstracts with Programs Vol. 42, No. 5. “Recognizing Earth Science Misconceptions and Reconstructing Knowledge through Conceptual-Change-Teaching”. The ESLP were released to the public in January 2009 by the Earth Science Literacy Organizing Committee and can be found at http://www.earthscienceliteracy.org/index.html. Each day of the first nine days of both Institutes was focused on one of the nine ESLP Big Ideas; the tenth day emphasized integration of concepts across all of the ESLP Big Ideas. Throughout each day, Michigan Tech graduate student facilitators and professors from Michigan Tech and Grand Valley State University consistantly focused teaching and learning on the day's Big Idea. Many Earth Science experts from Michigan Tech and Grand Valley State University joined the MiTEP teachers in the field or on campus, giving presentations on the latest research in their area that was related to that Big Idea. Field sites were chosen for their unique geological features as well as for the “sense of place” each site provided. Preliminary research findings indicate that this collaborative design

  2. Designing Surveys for Language Programs.

    Science.gov (United States)

    Brown, James Dean

    A discussion of survey methodology for investigating second language programs and instruction examines two methods: oral interviews and written questionnaires. Each method is defined, and variations are explored. For interviews, this includes individual, group, and telephone interviews. For questionnaires, this includes self-administered and…

  3. Designing Crop Simulation Web Service with Service Oriented Architecture Principle

    Science.gov (United States)

    Chinnachodteeranun, R.; Hung, N. D.; Honda, K.

    2015-12-01

    Crop simulation models are efficient tools for simulating crop growth processes and yield. Running crop models requires data from various sources as well as time-consuming data processing, such as data quality checking and data formatting, before those data can be inputted to the model. It makes the use of crop modeling limited only to crop modelers. We aim to make running crop models convenient for various users so that the utilization of crop models will be expanded, which will directly improve agricultural applications. As the first step, we had developed a prototype that runs DSSAT on Web called as Tomorrow's Rice (v. 1). It predicts rice yields based on a planting date, rice's variety and soil characteristics using DSSAT crop model. A user only needs to select a planting location on the Web GUI then the system queried historical weather data from available sources and expected yield is returned. Currently, we are working on weather data connection via Sensor Observation Service (SOS) interface defined by Open Geospatial Consortium (OGC). Weather data can be automatically connected to a weather generator for generating weather scenarios for running the crop model. In order to expand these services further, we are designing a web service framework consisting of layers of web services to support compositions and executions for running crop simulations. This framework allows a third party application to call and cascade each service as it needs for data preparation and running DSSAT model using a dynamic web service mechanism. The framework has a module to manage data format conversion, which means users do not need to spend their time curating the data inputs. Dynamic linking of data sources and services are implemented using the Service Component Architecture (SCA). This agriculture web service platform demonstrates interoperability of weather data using SOS interface, convenient connections between weather data sources and weather generator, and connecting

  4. Turning challenges into design principles: Telemonitoring systems for patients with multiple chronic conditions.

    Science.gov (United States)

    Sultan, Mehwish; Kuluski, Kerry; McIsaac, Warren J; Cafazzo, Joseph A; Seto, Emily

    2018-01-01

    People with multiple chronic conditions often struggle with managing their health. The purpose of this research was to identify specific challenges of patients with multiple chronic conditions and to use the findings to form design principles for a telemonitoring system tailored for these patients. Semi-structured interviews with 15 patients with multiple chronic conditions and 10 clinicians were conducted to gain an understanding of their needs and preferences for a smartphone-based telemonitoring system. The interviews were analyzed using a conventional content analysis technique, resulting in six themes. Design principles developed from the themes included that the system must be modular to accommodate various combinations of conditions, reinforce a routine, consolidate record keeping, as well as provide actionable feedback to the patients. Designing an application for multiple chronic conditions is complex due to variability in patient conditions, and therefore, design principles developed in this study can help with future innovations aimed to help manage this population.

  5. Electronic automation of LRFD design programs.

    Science.gov (United States)

    2010-03-01

    The study provided electronic programs to WisDOT for designing pre-stressed girders and piers using the Load : Resistance Factor Design (LRFD) methodology. The software provided is intended to ease the transition to : LRFD for WisDOT design engineers...

  6. Developing design principles for a Virtual Hospice: improving access to care.

    Science.gov (United States)

    Taylor, Andrea; French, Tara; Raman, Sneha

    2018-03-01

    Providing access to hospice services will become increasingly difficult due to the pressures of an ageing population and limited resources. To help address this challenge, a small number of services called Virtual Hospice have been established. This paper presents early-stage design work on a Virtual Hospice to improve access to services provided by a hospice (Highland Hospice) serving a largely remote and rural population in Scotland, UK. The study was structured as a series of Experience Labs with Highland Hospice staff, healthcare professionals and patients. Experience Labs employ a participatory design approach where participants are placed at the centre of the design process, helping to ensure that the resultant service meets their needs. Data from the Experience Labs were analysed using qualitative thematic analysis and design analysis. A number of themes and barriers to accessing Highland Hospice services were identified. In response, an initial set of seven design principles was developed. Design principles are high-level guidelines that are used to improve prioritisation and decision making during the design process by ensuring alignment with research insights. The design principles were piloted with a group of stakeholders and gained positive feedback. The design principles are intended to guide the ongoing development of the Highland Hospice Virtual Hospice. However, the challenges faced by Highland Hospice in delivering services in a largely remote and rural setting are not unique. The design principles, encompassing digital and non-digital guidelines, or the design approach could be applied by other hospices in the UK or overseas. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  7. Fuel channel in-service inspection programs program design for maximum cost effectiveness

    International Nuclear Information System (INIS)

    Van den Brekel, N.C.

    1995-01-01

    Inspection is an integral part of fuel channel life management strategy. Inspection data is used to assess the state of reactor core integrity and provide the information necessary to optimize long term maintenance programs. This paper will provide an overview of the structured approach to developing fuel channel inspection programs within OHN. The inspection programs are designed to balance the resources utilized (cost, outage time, and dose expenditure) with the benefits provided by the inspection data obtained (improved knowledge of component status, degradation mechanisms and rates, etc..). The CANDU community has yet to have a fuel channel operate for a full 30 year design life. Since research programs can not fully simulate reactor operating conditions, inspections become an essential feature of the life management strategy as the components age. Inspection programs often include activities designed to develop predictive capability for long term fuel channel behaviour and provide early warning of changes in behaviour. It should be noted that although this paper addresses the design of fuel channel inspection programs, the basic principles presented can be applied to the design of inspection programs for any major power plant component or system. (author)

  8. Effective safety training program design

    International Nuclear Information System (INIS)

    Chilton, D.A.; Lombardo, G.J.; Pater, R.F.

    1991-01-01

    Changes in the oil industry require new strategies to reduce costs and retain valuable employees. Training is a potentially powerful tool for changing the culture of an organization, resulting in improved safety awareness, lower-risk behaviors and ultimately, statistical improvements. Too often, safety training falters, especially when applied to pervasive, long-standing problems. Stepping, Handling and Lifting injuries (SHL) more commonly known as back injuries and slips, trips and falls have plagued mankind throughout the ages. They are also a major problem throughout the petroleum industry. Although not as widely publicized as other immediately-fatal accidents, injuries from stepping, materials handling, and lifting are among the leading causes of employee suffering, lost time and diminished productivity throughout the industry. Traditional approaches have not turned the tide of these widespread injuries. a systematic safety training program, developed by Anadrill Schlumberger with the input of new training technology, has the potential to simultaneously reduce costs, preserve employee safety, and increase morale. This paper: reviews the components of an example safety training program, and illustrates how a systematic approach to safety training can make a positive impact on Stepping, Handling and Lifting injuries

  9. ANALYSIS OF FUZZY QUEUES: PARAMETRIC PROGRAMMING APPROACH BASED ON RANDOMNESS - FUZZINESS CONSISTENCY PRINCIPLE

    Directory of Open Access Journals (Sweden)

    Dhruba Das

    2015-04-01

    Full Text Available In this article, based on Zadeh’s extension principle we have apply the parametric programming approach to construct the membership functions of the performance measures when the interarrival time and the service time are fuzzy numbers based on the Baruah’s Randomness- Fuzziness Consistency Principle. The Randomness-Fuzziness Consistency Principle leads to defining a normal law of fuzziness using two different laws of randomness. In this article, two fuzzy queues FM/M/1 and M/FM/1 has been studied and constructed their membership functions of the system characteristics based on the aforesaid principle. The former represents a queue with fuzzy exponential arrivals and exponential service rate while the latter represents a queue with exponential arrival rate and fuzzy exponential service rate.

  10. Using Persuasive Design Principles in Motivational Feeling towards Children Dental Anxiety (CDA)

    Science.gov (United States)

    Salam, Sobihatun Nur-Abdul; Yahaya, Wan Ahmad Jaafar-Wan; Ali, Azillah-Mohd

    This paper is focusing the potential use of persuasive design principles in motivating children's dental anxiety. The main intention of the paper is to emphasize an attempt of how persuasive design principle can be designed into educational material using CD ROM based multimedia learning environment to overcome the CDA. Firstly, we describe a problem domain which discuss about the universal feeling of CDA and secondly the current practices in handling those negative feelings. Thirdly, the conceptual background of PMLE and how the principle has been applied in designing the information interfaces and presentation of a persuasive multimedia learning environment (PMLE) are described. Fourthly, an experimental design was used to validate the effects of prototype which assessed children dental anxiety level before and after the demonstration and utilization of a PMLE. Primary school children age between seven and nine years old are selected as respondents. Fifthly, the result of the study has revealed the feedback from children regarding baseline test and children dental anxiety test. It shows how by using persuasive design principles as an overall strategy in designing PMLE was able to motivate children feelings towards dental anxiety and could let the children behave in a good manner for dental visit in the future.

  11. Novel Principles and Techniques to Create a Natural Design in Female Hairline Correction Surgery.

    Science.gov (United States)

    Park, Jae Hyun

    2015-12-01

    Female hairline correction surgery is becoming increasingly popular. However, no guidelines or methods of female hairline design have been introduced to date. The purpose of this study was to create an initial framework based on the novel principles of female hairline design and then use artistic ability and experience to fine tune this framework. An understanding of the concept of 5 areas (frontal area, frontotemporal recess area, temporal peak, infratemple area, and sideburns) and 5 points (C, A, B, T, and S) is required for female hairline correction surgery (the 5A5P principle). The general concepts of female hairline correction surgery and natural design methods are, herein, explained with a focus on the correlations between these 5 areas and 5 points. A natural and aesthetic female hairline can be created with application of the above-mentioned concepts. The 5A5P principle of forming the female hairline is very useful in female hairline correction surgery.

  12. Pacific Canada's Rockfish Conservation Areas: using Ostrom's design principles to assess management effectiveness

    Directory of Open Access Journals (Sweden)

    Darienne Lancaster

    2015-09-01

    Full Text Available International declines in marine biodiversity have lead to the creation of marine protected areas and fishery reserve systems. In Canada, 164 Rockfish Conservation Areas (RCAs were implemented between 2003 and 2007 and now cover 4847.2 km² of ocean. These reserves were created in response to widespread concern from fishers and nongovernmental organizations about inshore rockfish (genus Sebastes population declines. We used the design principles for effective common-pool resource management systems, originally developed by Elinor Ostrom, to assess the social and ecological effectiveness of these conservation areas more than 10 years after their initial implementation. We assessed the relative presence or absence of each design principle within current RCA management. We found that 2 of the 11 design principles were moderately present in the recreational fishery. All other design principles were lacking for the recreational sector. We found that 2 design principles were fully present and 5 were moderately present in the commercial sector. Four design principles were lacking in the commercial sector. Based on this analysis, we highlight 4 main areas for management improvement: (1 create an education and outreach campaign to explain RCA rules, regulations, boundaries, and the need for marine conservation; (2 increase monitoring of users and resources to discourage noncompliance and gather the necessary data to create social buy-in for marine conservation; (3 encourage informal nested governance through stakeholder organizations for education and self-regulation (e.g. fisher to fisher; and (4 most importantly, create a formal, decadal RCA review process to gather stakeholder input and make amendments to regulations and RCA boundaries. This information can be used to inform spatial management systems both in Canada and internationally. This analysis also contributes to a growing literature on effectively scaling up small-scale management techniques

  13. Review: Janice M. Morse & Linda Niehaus (2009). Mixed method design: principles and procedures

    OpenAIRE

    Öhlen, Joakim

    2010-01-01

    Mixed-Method-Designs, in denen quantitative und qualitative Methoden Verwendung finden, erfreuen sich zunehmender Beliebtheit für die Untersuchung komplexer Phänomene. Die vorliegende Besprechung beschäftigt sich in diesem Zusammenhang mit dem Buch "Mixed Method Design: Principles and Procedures" von Janice M. MORSE und Linda NIEHAUS, die für solche Designs Kern- und Ergänzungskomponenten zu identifizieren versuchen. Hierzu differenzieren sie zwischen Projekten, die einer eher deduktiven oder...

  14. Review: Janice M. Morse & Linda Niehaus (2009). Mixed Method Design: Principles and Procedures

    OpenAIRE

    Öhlen, Joakim

    2010-01-01

    Mixed method design related to the use of a combination of methods, usually quantitative and qualitative, is increasingly used for the investigation of complex phenomena. This review discusses the book, "Mixed Method Design: Principles and Procedures," by Janice M. MORSE and Linda NIEHAUS. A distinctive feature of their approach is the consideration of mixed methods design out of a core and a supplemental component. In order to define these components they emphasize the overall conceptual dir...

  15. The roles and uses of design principles for developing the trialogical approach on learning

    Directory of Open Access Journals (Sweden)

    Kari Kosonen

    2011-12-01

    Full Text Available In the present paper, the development and use of a specific set of pedagogical design principles in a large research and development project are analysed. The project (the Knowledge Practices Laboratory developed technology and a pedagogical approach to support certain kinds of collaborative knowledge creation practices related to the ‘trialogical' approach on learning. The design principles for trialogical learning are examined from three main developmental perspectives that were emphasised in the project: theory, pedagogy, and technology. As expected, the design principles had many different roles but not as straightforward or overarching as was planned. In their outer form they were more resistant to big changes than was expected but they were elaborated and specified during the process. How theories change in design-based research is discussed on the basis of the analysis. Design principles are usually seen as providing a bridge between theory and practice, but the present case showed that also complementary, more concrete frameworks are needed for bridging theory to practical pedagogical or technical design solutions.

  16. Relationship between Maximum Principle and Dynamic Programming for Stochastic Recursive Optimal Control Problems and Applications

    Directory of Open Access Journals (Sweden)

    Jingtao Shi

    2013-01-01

    Full Text Available This paper is concerned with the relationship between maximum principle and dynamic programming for stochastic recursive optimal control problems. Under certain differentiability conditions, relations among the adjoint processes, the generalized Hamiltonian function, and the value function are given. A linear quadratic recursive utility portfolio optimization problem in the financial engineering is discussed as an explicitly illustrated example of the main result.

  17. Treatment Plans in Psychiatric Community Housing Programs : Do They Reflect Rehabilitation Principles?

    NARCIS (Netherlands)

    de Heer-Wunderink, Charlotte; Visser, Ellen; Caro-Nienhuis, Annemarie D.; van Weeghel, Jaap; Sytema, Sjoerd; Wiersma, Durk

    2012-01-01

    Objective: This study examined the extent to which treatment plans of service users of community housing programs measure up to rehabilitation principles according to the Choose-Get-Keep model of psychiatric rehabilitation. The study evaluates whether these plans correspond with service-user and

  18. Financial Sector Assessment Program : Nigeria - Basel Core Principles for Effective Banking Supervision

    OpenAIRE

    International Monetary Fund; World Bank

    2013-01-01

    The assessment of the current state of the implementation of the Basel Core Principles (BCP) for effective banking supervision in Nigeria, against the BCP methodology issued by the Basel Committee on Banking Supervision (BCBS) in October 2006, was completed between August 27 and September 19, 2012, as part of a Financial Sector Assessment Program (FSAP) update, undertaken jointly by the Fu...

  19. A study of usability principles and interface design for mobile e-books.

    Science.gov (United States)

    Wang, Chao-Ming; Huang, Ching-Hua

    2015-01-01

    This study examined usability principles and interface designs in order to understand the relationship between the intentions of mobile e-book interface designs and users' perceptions. First, this study summarised 4 usability principles and 16 interface attributes, in order to conduct usability testing and questionnaire survey by referring to Nielsen (1993), Norman (2002), and Yeh (2010), who proposed the usability principles. Second, this study used the interviews to explore the perceptions and behaviours of user operations through senior users of multi-touch prototype devices. The results of this study are as follows: (1) users' behaviour of operating an interactive interface is related to user prior experience; (2) users' rating of the visibility principle is related to users' subjective perception but not related to user prior experience; however, users' ratings of the ease, efficiency, and enjoyment principles are related to user prior experience; (3) the interview survey reveals that the key attributes affecting users' behaviour of operating an interface include aesthetics, achievement, and friendliness. This study conducts experiments to explore the effects of users’ prior multi-touch experience on users’ behaviour of operating a mobile e-book interface and users’ rating of usability principles. Both qualitative and quantitative data analyses were performed. By applying protocol analysis, key attributes affecting users’ behaviour of operation were determined.

  20. Slide layout and integrated design (SLIDE) program

    International Nuclear Information System (INIS)

    Roberts, S.G.

    1975-01-01

    SLIDE is a FORTRAN IV program for producing 35 mm color slides on the Control Data CYBER-74. SLIDE interfaces with the graphics package, DISSPLA, on the CYBER-74. It was designed so that persons with no previous computer experience can easily and quickly generate their own textual 35 mm color slides for verbal presentations. SLIDE's features include seven different colors, five text sizes, ten tab positions, and two page sizes. As many slides as desired may be produced during any one run of the program. Each slide is designed to represent an 8 1 / 2 in. x 11 in. or an 11 in. x 8 1 / 2 in. page. The input data cards required to run the SLIDE program and the program output are described. Appendixes contain a sample program run showing input, output, and the resulting slides produced and a FORTRAN listing of the SLIDE program. (U.S.)

  1. Double degree master program: Optical Design

    Science.gov (United States)

    Bakholdin, Alexey; Kujawinska, Malgorzata; Livshits, Irina; Styk, Adam; Voznesenskaya, Anna; Ezhova, Kseniia; Ermolayeva, Elena; Ivanova, Tatiana; Romanova, Galina; Tolstoba, Nadezhda

    2015-10-01

    Modern tendencies of higher education require development of master programs providing achievement of learning outcomes corresponding to quickly variable job market needs. ITMO University represented by Applied and Computer Optics Department and Optical Design and Testing Laboratory jointly with Warsaw University of Technology represented by the Institute of Micromechanics and Photonics at The Faculty of Mechatronics have developed a novel international master double-degree program "Optical Design" accumulating the expertise of both universities including experienced teaching staff, educational technologies, and experimental resources. The program presents studies targeting research and professional activities in high-tech fields connected with optical and optoelectronics devices, optical engineering, numerical methods and computer technologies. This master program deals with the design of optical systems of various types, assemblies and layouts using computer modeling means; investigation of light distribution phenomena; image modeling and formation; development of optical methods for image analysis and optical metrology including optical testing, materials characterization, NDT and industrial control and monitoring. The goal of this program is training a graduate capable to solve a wide range of research and engineering tasks in optical design and metrology leading to modern manufacturing and innovation. Variability of the program structure provides its flexibility and adoption according to current job market demands and personal learning paths for each student. In addition considerable proportion of internship and research expands practical skills. Some special features of the "Optical Design" program which implements the best practices of both Universities, the challenges and lessons learnt during its realization are presented in the paper.

  2. Design and Development of a Nonverbal Program

    Science.gov (United States)

    Thiagarajan, S.

    1973-01-01

    Problems were encountered in designing an illustrated program on contraceptive techniques for India's rural population where illiteracy is high and hundreds of different languages are spoken. Field trials of a picture program indicated the ability to "read" a picture is an acquired skill. (Author)

  3. Microprocessors principles and applications

    CERN Document Server

    Debenham, Michael J

    1979-01-01

    Microprocessors: Principles and Applications deals with the principles and applications of microprocessors and covers topics ranging from computer architecture and programmed machines to microprocessor programming, support systems and software, and system design. A number of microprocessor applications are considered, including data processing, process control, and telephone switching. This book is comprised of 10 chapters and begins with a historical overview of computers and computing, followed by a discussion on computer architecture and programmed machines, paying particular attention to t

  4. Design Principles for Serious Video Games in Mathematics Education: From Theory to Practice

    Directory of Open Access Journals (Sweden)

    Konstantinos Chorianopoulos

    2014-09-01

    Full Text Available There is growing interest in the employment of serious video games in science education, but there are no clear design principles. After surveying previous work in serious video game design, we highlighted the following design principles: 1 engage the students with narrative (hero, story, 2 employ familiar gameplay mechanics from popular video games, 3 engage students into constructive trial and error game-play and 4 situate collaborative learning. As illustrated examples we designed two math video games targeted to primary education students. The gameplay of the math video games embeds addition operations in a seamless way, which has been inspired by that of classic platform games. In this way, the students are adding numbers as part of popular gameplay mechanics and as a means to reach the video game objective, rather than as an end in itself. The employment of well-defined principles in the design of math video games should facilitate the evaluation of learning effectiveness by researchers. Moreover, educators can deploy alternative versions of the games in order to engage students with diverse learning styles. For example, some students might be motived and benefited by narrative, while others by collaboration, because it is unlikely that one type of serious video game might fit all learning styles. The proposed principles are not meant to be an exhaustive list, but a starting point for extending the list and applying them in other cases of serious video games beyond mathematics and learning.

  5. On the importance of agile communication skills in BPM education: Design principles for international seminars

    Directory of Open Access Journals (Sweden)

    Jan vom Brocke

    2012-12-01

    Full Text Available Business Process Management (BPM has evolved as an integrated management discipline that aims to enable organizations to continuously innovate and improve their operations. BPM experts are exposed to communication processes involving people from various backgrounds (e.g., various business areas, fields of expertise, and cultures. Research in applied linguistics has shown that it is difficult to plan for constellations of such communication processes; thus, agile communication skills are vital for successful business communication. Teaching programs for BPM, however, do not account for these skills. Rather, they mainly address methods for the analysis, implementation, and management of business processes. As a result, graduates—though they may be technically and methodologically apt—face unexpected challenges due to communication deficiencies in BPM projects. BPM research has shown that deficiencies in communication are in fact among the most frequent reasons for project failure. In this paper, we present a course setting to teach agile communication skills in BPM education. The approach is informed by literature on BPM education as well as theories from virtual collaboration education. We have evaluated it in an international virtual seminar involving seven European universities. We argue for the importance of agile communication skills in BPM education. In addition, we present design principles for courses to teach agile communication skills that can be applied by fellow academics.

  6. Urban Principle of Water Sensitive Design in Kampung Kamboja at Pontianak City

    Science.gov (United States)

    Hasriyanti, N.; Ryanti, E.

    2017-07-01

    This study will define the design principles of settlement area banks of the Kapuas Pontianak to approach the concept of water sensitive urban design (WSUD) in densely populated residential areas. Using a case study of a region densely located on the banks of the river with engineering literature to formulate the aspects taken into consideration and the components are arranged in the design, analysis descriptive paradigm rationalistic to identify the characteristics of residential areas riverbank with consideration of elements WSUD and formulate design principles residential area that is sensitive to water. This research is important to do because of problems related to the water management system in the settlement bank of the river in the city of Pontianak do not maximize. So that the primacy of this study contains several objectives to be achieved is to identify the characteristics of the settlement area riverbanks under consideration aspects areas design that is sensitive to water and principle areas design that will formulate the structure of the existing problems related to the needs of the community infrastructure facilities infrastructure neighborhoods and formulate and create guidelines for appropriate technology for integrated water management systems in the residential area of the riverbank and engineering design for the settlements are sensitive to water (WSUD). The final aim of the study is expected to achieve water management systems in residential areas by utilizing the abundant rainwater availability by using LID (Low Impact Development) through the concept of urban design that sensitive water

  7. Efficiency evaluation of grant policy in sport by principles of program financing

    Directory of Open Access Journals (Sweden)

    Vladimír Hobza

    2010-03-01

    Full Text Available The paper concerns with mutual interconnection of goals of municipal development concepts and methods of their assessment. Based on grant policy of selected municipalities (regions, communities and on the principles of program financing, a specific method of evaluation performance is suggested, which enables to evaluate closer control of sport development, visions, proclaimed goals and sport support programs. The principle of the proposed procedure is based on the use of indicators and methods: CEA, CBA, CUA and CMA in program financing of sport - a field where it is not possible to calculate only direct economic results but it is necessary to consider the impact of externalities (benefits. The authors suggest procedures, which lead to a higher level of control, transparency and efficiency of public spending in the municipal sphere. The goal of this contribution is to point out possible means of assessing grant proposals, as a support tool for decision-making and subsequent control.

  8. Designing an orientation program for new faculty.

    Science.gov (United States)

    Holyfield, Lavern J; Berry, Charles W

    2008-12-01

    The Faculty Development Committee (FDC) at Baylor College of Dentistry (BCD) is charged with providing programs and activities that facilitate the success of existing faculty in the constantly changing environment of academia. In response to concerns regarding the challenges wrought by current and projected shortages of dental faculty across the nation, the FDC was prompted to assess development opportunities available to BCD faculty. A professional development resource that we found deficient was a formal, comprehensive orientation program for newly hired faculty. To guide the efforts of the committee in developing this program, a survey was designed and administered during an annual faculty retreat. Respondents were new and junior faculty, senior faculty, and some administrators. The results of the survey to determine requirements for new faculty orientation became the basis for formalizing BCD's new faculty orientation program. This article provides an overview of the new faculty orientation process from design to program implementation and describes the development and use of a faculty survey to determine the fundamental elements of a faculty development program, identification of essential individuals for designing/implementing the program, and implementation of a new faculty orientation program at BCD.

  9. Design principles of water sensitive in settlement area on the river banks

    Science.gov (United States)

    Ryanti, E.; Hasriyanti, N.; Utami, W. D.

    2018-03-01

    This research will formulate the principle of designing settlement area of Kapuas River Pontianak with the approach of water sensitive concept of urban design (WSUD) the densely populated settlement area. By using a case study the approach that is a dense settlement area located on the banks of the river with literature study techniques to formulate the aspects considered and components that are set in the design, descriptive analysis with the rationalistic paradigm for identification characteristics of the settlement in the river banks areas with consideration of WSUD elements and formulate the principles of designing water-sensitive settlement areas. This research is important to do because the problems related to the water management system in the existing riverside settlement in Pontianak has not been maximal to do. So the primary of this research contains several objectives that will be achieved that is identifying the characteristics of riverside settlement area based on consideration of design aspects of the area that are sensitive to water and the principle of designing the area so that the existing problem structure will be formulated in relation to the community’s need for infrastructure in settlement environment and formulate and develop appropriate technology guidelines for integrated water management systems in riverside settlement areas and design techniques for water-sensitive settlements (WSUD).

  10. To Design and Evaluate a 12th Grade Course in the Principles of Economics; Final Report.

    Science.gov (United States)

    Wiggins, Suzanne E.; Sperling, John G.

    Reported is the design, development, and evaluation of a one-semester course on the principles of economics for twelfth grade students. The course is intended to develop students' capacity for economic reasoning through economic theory and empirical research. To do this, teaching materials and innovative techniques for teacher training were…

  11. The pit ventilation features and the design principle of ventilation system in trackless mining uranium mine

    International Nuclear Information System (INIS)

    Deng Wenhui; Zhou Xinghuo; Li Xianjie

    2001-01-01

    According to the pit arrangement features of trackless mining uranium mine, based on the fundamental of radon permeation and control, and analysis of radon pollution characteristics and radon education, the design principle of ventilation system in trackless mining uranium mine has been raised

  12. Opportunity recognition in entrepreneurship education, design principles on fostering competent entrepreneurs in the science domain

    NARCIS (Netherlands)

    Nab, J.; Beugels, J.; van Keulen, H.; Oost, H.; Pilot, A.

    2008-01-01

    This paper is part of a research project focusing on educational design principles that should help students with a background in Science to become competent with respect to opportunity recognition in business. The recognition of business opportunities is one of the basic competencies of

  13. The Roles and Uses of Design Principles for Developing the Trialogical Approach on Learning

    Science.gov (United States)

    Paavola, Sami; Lakkala, Minna; Muukkonen, Hanni; Kosonen, Kari; Karlgren, Klas

    2011-01-01

    In the present paper, the development and use of a specific set of pedagogical design principles in a large research and development project are analysed. The project (the Knowledge Practices Laboratory) developed technology and a pedagogical approach to support certain kinds of collaborative knowledge creation practices related to the…

  14. PBMR phase 1 study: Seismic and structural design consideration - An overview of principles

    International Nuclear Information System (INIS)

    Wium, D.J.W.

    1997-01-01

    This paper briefly reviews the principles involved in the planning and design of the proposed facility to cater for seismic and structural loads. The conceptual layout is discussed, as well as the different load characteristics and scenarios. An outline is given of model used to estimate the seismic loads, whereafter the different analytical models are discussed. (author)

  15. Sign Redesign: Applying Design Principles to Improve Signage in an Academic Library

    Directory of Open Access Journals (Sweden)

    Sheila Kasperek

    2014-05-01

    Full Text Available When the Mansfield University library’s Special Events and Customer Service Committee created a communications plan for the library, the opportunity presented itself to overhaul the library signs. Applying basic design principles of contrast, alignment, and repetition along with standards from the Americans with Disabilities Act, the library improved the visual communications within the library. Patrons can now read signs from a distance and understand their purpose. Using common design elements, the library began presenting official library information more cohesively. Extending beyond signs, these design principles are now part of the library’s print publications and promotional items. With this consistency, the library brand is more easily recognizable both within the library and across campus. This article describes some basic elements of design and the process of redesigning the signs.

  16. First principles design of a core bioenergetic transmembrane electron-transfer protein

    Energy Technology Data Exchange (ETDEWEB)

    Goparaju, Geetha; Fry, Bryan A.; Chobot, Sarah E.; Wiedman, Gregory; Moser, Christopher C.; Leslie Dutton, P.; Discher, Bohdana M.

    2016-05-01

    Here we describe the design, Escherichia coli expression and characterization of a simplified, adaptable and functionally transparent single chain 4-α-helix transmembrane protein frame that binds multiple heme and light activatable porphyrins. Such man-made cofactor-binding oxidoreductases, designed from first principles with minimal reference to natural protein sequences, are known as maquettes. This design is an adaptable frame aiming to uncover core engineering principles governing bioenergetic transmembrane electron-transfer function and recapitulate protein archetypes proposed to represent the origins of photosynthesis. This article is part of a Special Issue entitled Biodesign for Bioenergetics — the design and engineering of electronic transfer cofactors, proteins and protein networks, edited by Ronald L. Koder and J.L. Ross Anderson.

  17. A CAL Program to Teach the Basic Principles of Genetic Engineering--A Change from the Traditional Approach.

    Science.gov (United States)

    Dewhurst, D. G.; And Others

    1989-01-01

    An interactive computer-assisted learning program written for the BBC microcomputer to teach the basic principles of genetic engineering is described. Discussed are the hardware requirements software, use of the program, and assessment. (Author/CW)

  18. The concept and principles of sustainable architectural design for national parks in Serbia

    OpenAIRE

    Milošević Predrag

    2004-01-01

    The paper elaborates the concept of sustainable architectural design that has come to the forefront in the last 20 years, and in the light of the National Park. This concept recognizes that human civilization is an integral part of the natural world and that nature must be preserved and perpetuated if the human community itself is to survive. Sustainable design articulates this idea through developments that exemplify the principles of conservation and encourage the application of those princ...

  19. High-throughput spectrometer designs in a compact form-factor: principles and applications

    Science.gov (United States)

    Norton, S. M.

    2013-05-01

    Many compact, portable Raman spectrometers have entered the market in the past few years with applications in narcotics and hazardous material identification, as well as verification applications in pharmaceuticals and security screening. Often, the required compact form-factor has forced designers to sacrifice throughput and sensitivity for portability and low-cost. We will show that a volume phase holographic (VPH)-based spectrometer design can achieve superior throughput and thus sensitivity over conventional Czerny-Turner reflective designs. We will look in depth at the factors influencing throughput and sensitivity and illustrate specific VPH-based spectrometer examples that highlight these design principles.

  20. Designing Social Interfaces Principles, Patterns, and Practices for Improving the User Experience

    CERN Document Server

    Crumlish, Christian

    2009-01-01

    From the creators of Yahoo!'s Design Pattern Library, Designing Social Interfaces provides you with more than 100 patterns, principles, and best practices, along with salient advice for many of the common challenges you'll face when starting a social website. Designing sites that foster user interaction and community-building is a valuable skill for web developers and designers today, but it's not that easy to understand the nuances of the social web. Now you have help. Christian Crumlish and Erin Malone share hard-won insights into what works, what doesn't, and why. You'll learn how to bala

  1. Software Engineering Design Principles Applied to Instructional Design: What Can We Learn from Our Sister Discipline?

    Science.gov (United States)

    Adnan, Nor Hafizah; Ritzhaupt, Albert D.

    2018-01-01

    The failure of many instructional design initiatives is often attributed to poor instructional design. Current instructional design models do not provide much insight into design processes for creating e-learning instructional solutions. Given the similarities between the fields of instructional design and software engineering, instructional…

  2. Outline of principle of design construction of demolished concrete from electric power plant

    International Nuclear Information System (INIS)

    Takahashi, Tomohiko; Sakagami, Takeharu; Inagaki, Hirokazu; Morozumi, Hironori; Muranaka, Kenji

    2005-01-01

    'The principle of design construction of recycled demolished concrete from electric power plant' (a plan) is going to be published by TSCE Concrete Committee in 2005. The abstract of the above principle is described. A large amount of demolished concrete is generated by decommissioning of atomic power plant. About 450,000 to 500,000t of concrete with small radiation level per an atomic power plant will be generated. This report included decommissioning of Tokai power plant, characteristics of subject of demolished concrete, the recycled demolished concrete, fresh conditions of the recycled demolished concrete, the strength, deformation properties, durability, alkali silica reactivity of them and control measurement. (S.Y.)

  3. Operationalising the Lean principles in maternity service design using 3P methodology.

    Science.gov (United States)

    Smith, Iain

    2016-01-01

    The last half century has seen significant changes to Maternity services in England. Though rates of maternal and infant mortality have fallen to very low levels, this has been achieved largely through hospital admission. It has been argued that maternity services may have become over-medicalised and service users have expressed a preference for more personalised care. NHS England's national strategy sets out a vision for a modern maternity service that continues to deliver safe care whilst also adopting the principles of personalisation. Therefore, there is a need to develop maternity services that balance safety with personal choice. To address this challenge, a maternity unit in North East England considered improving their service through refurbishment or building new facilities. Using a design process known as the production preparation process (or 3P), the Lean principles of understanding user value, mapping value-streams, creating flow, developing pull processes and continuous improvement were applied to the design of a new maternity department. Multiple stakeholders were engaged in the design through participation in a time-out (3P) workshop in which an innovative pathway and facility for maternity services were co-designed. The team created a hybrid model that they described as "wrap around care" in which the Lean concept of pull was applied to create a service and facility design in which expectant mothers were put at the centre of care with clinicians, skills, equipment and supplies drawn towards them in line with acuity changes as needed. Applying the Lean principles using the 3P method helped stakeholders to create an innovative design in line with the aspirations and objectives of the National Maternity Review. The case provides a practical example of stakeholders applying the Lean principles to maternity services and demonstrates the potential applicability of the Lean 3P approach to design healthcare services in line with policy requirements.

  4. Mapping of Affordance and Activity as the Biophilic Design Principle of Blue Lagoon Tourism Area Yogyakarta

    Directory of Open Access Journals (Sweden)

    Saptorini Hastuti

    2018-01-01

    Full Text Available Bathing and playing in the river is not a new phenomenon for some people. But this experience creates a recreational spirit on the Tepusriver which is now better known as the Blue Lagoon. This area is a term for the settlement that is split a piece of the river in the dusun Ndalem Ngemplak Sleman. Its tributaries are clear and blue, surrounded by some springs with natural bamboo groves and old trees that invite local and around communities for recreation. The local community has anticipated it by responding to the communities’ demands as well as the recreation area. Appear sporadically “warungs” and recreational activities follow-up though not yet grown in conceptual. This paper aims to study the map of affordance and activity of previous research findings and could be used to the biophilic design to afford the health, productivity, and wellbeing in the tourism area. The method is by synthesizing the previous research findings in 2016, some relevant urban design theories, and biophilic design principle. The conclusion is paid attention to two main principles. The first principle is maximizing the utilization of existing natural properties and the existing cultural skills into its development to nourish visitors both physically and psychologically. The second principle is the Government, and Non-Government Organizations (i.e., expertise, academics, universities, investors support, both policy and financially, in many sectors: tourism, environment, and infrastructure.

  5. Logic-programming language enriches design processes

    Energy Technology Data Exchange (ETDEWEB)

    Kitson, B.; Ow-Wing, K.

    1984-03-22

    With the emergence of a set of high-level CAD tools for programmable logic devices, designers can translate logic into functional custom devices simply and efficiently. The core of the package is a blockstructured hardware description language called PLPL, for ''programmable-logic programming language.'' The cheif advantage of PLPL lies in its multiple input formats, which permit different design approaches for a variety of design problems. The higher the level of the approach, the closer PLPL will come to directly specifying the desired function. Intermediate steps in the design process can be eliminated, along with the errors that might have been generated during those steps.

  6. Seismic design principles for the German fast breeder reactor SNR2

    International Nuclear Information System (INIS)

    Rangette, A.M.; Peters, K.A.

    1988-01-01

    The leading aim of a seismic design is, besides protection against seismic impacts, not to enhance the overall risk in the absence of seismic vibrations and, secondly, to avoid competition between operational needs and a seismic structural design. This approach is supported by avoiding overconservatism in the assumption of seismic loads and in the calculation of the structural response. Accordingly the seismic principles are stated as follows: restriction to German or equivalent low seismicity sites with intensities (SSE) lower VIII at frequency lower than 10 -4 /year; best estimate of seismic input-data without further conservatism; no consideration of OBE. The structural design principles are: 1. The secondary character of the seismic excitation is explicitly accounted for; 2. Energy absorption is allowed for by ductility of materials and construction. Accordingly strain criteria are used for failure predictions instead of stress criteria. (author). 1 fig

  7. Blockchain to Rule the Waves - Nascent Design Principles for Reducing Risk and Uncertainty in Decentralized Environments

    DEFF Research Database (Denmark)

    Nærland, Kristoffer; Müller-Bloch, Christoph; Beck, Roman

    2017-01-01

    Many decentralized, inter-organizational environments such as supply chains are characterized by high transactional uncertainty and risk. At the same time, blockchain technology promises to mitigate these issues by introducing certainty into economic transactions. This paper discusses the findings...... of a Design Science Research project involving the construction and evaluation of an information technology artifact in collaboration with Maersk, a leading international shipping company, where central documents in shipping, such as the Bill of Lading, are turned into a smart contract on blockchain. Based...... on our insights from the project, we provide first evidence for preliminary design principles for applications that aim to mitigate the transactional risk and uncertainty in decentralized environments using blockchain. Both the artifact and the first evidence for emerging design principles are novel...

  8. Principles from history, community psychology and developmental psychology applied to community based programs for deinstitutionalized youth

    OpenAIRE

    Levine, Murray

    2007-01-01

    ABSTRACT: This article analyses the issues of the deinstitutionalization of youth, and the development of community based services, using some historical data and some of the principles of community psychology. The basic premise is that there is no such thing as a social vacuum. All programs are implemented and function in an elaborate social context. RESUMO: Este artigo analisa as questões referentes à desinstitunalização dos jovens e ao desenvolvimento de serviços ...

  9. Switzerland; Financial Sector Assessment Program: Factual Update: Basel Core Principles for Effective Banking Supervision

    OpenAIRE

    International Monetary Fund

    2007-01-01

    This technical note presents a factual update of the 2001 assessment of Switzerland’s compliance with the 1997 Basel Core Principles for Effective Banking Supervision (BCP), including a follow-up on implementation of the 2001 BCP assessment, undertaken in the context of the original Financial Sector Assessment Program in 2001. The note discusses that the Swiss Federal Banking Commission (SFBC) has made impressive progress both organizationally and to its supervisory practices to strengthen Sw...

  10. Formulation of engineering design principles for the treatment of irradiated fuel and associated radioactive waste

    International Nuclear Information System (INIS)

    Banford, A.W.; Hanson, B.C.; Scully, P.J.; Taylor, R.

    2007-01-01

    The industrial scale treatment of irradiated fuel in the UK has resulted in BNFL developing extensive experience of the process design, build, commissioning, and operation necessary for successful nuclear processing plant. Much of the design experience now resides in Nexia Solutions (formally BNFL Research and Development Division) who have always defined and undertaken the extensive development programmes necessary to underpin the design at all stages of the project life-cycle. Since the 1990's, Nexia Solutions has built up a large portfolio of plant designs for a range of spent fuel applications, from fuel conditioning to partitioning and transmutation. In addition, by investigation of a large and diverse portfolio of technologies Nexia Solutions has developed innovative concepts for plant design that could present significant economic savings on conventional approaches. Using this experience and the lessons learned, we have developed and refined our own engineering design principles necessary for the successful design of commercial spent fuel and waste treatment plant. Our approach is to advocate an integral concept, with both science and engineering designs working in parallel during development. 4 foundation principles for success have been identified: -) understand the strategic objective, -) adopt a risk driven programme, -) engage in engineering activities early, and -) timely application of appropriate engineering methodologies. 2 Case studies presented in this paper: first, the BNFL segregated effluent treatment plant and secondly, the selection of a pyrochemical process for recycle of fast reactor, demonstrate how this approach has been adopted and the benefits that have been gained

  11. Novel Designs for the Audio Mixing Interface Based on Data Visualisation First Principles

    OpenAIRE

    Dewey, Christopher; Wakefield, Jonathan P.

    2016-01-01

    Given the shortcomings of current audio mixing interfaces (AMIs) this study focuses on the development of alternative AMIs based on data visualisation first principles. The elementary perceptual tasks defined by Cleveland informed the design process. Two design ideas were considered for pan: using the elementary perceptual tasks ‘scale’ to display pan on either a single or multiple horizontal lines. Four design ideas were considered for level:\\ud using ‘length’, ‘area’, ‘saturation’ or ‘scala...

  12. The concept and principles of sustainable architectural design for national parks in Serbia

    Directory of Open Access Journals (Sweden)

    Milošević Predrag

    2004-01-01

    Full Text Available The paper elaborates the concept of sustainable architectural design that has come to the forefront in the last 20 years, and in the light of the National Park. This concept recognizes that human civilization is an integral part of the natural world and that nature must be preserved and perpetuated if the human community itself is to survive. Sustainable design articulates this idea through developments that exemplify the principles of conservation and encourage the application of those principles in our daily lives. A corollary concept, and one that supports sustainable design, is that of bio-regionalism - the idea that all life is established and maintained on a functional community basis and that all of these distinctive communities (bio-regions have mutually supporting life systems that are generally self-sustaining. The concept of sustainable design holds that future technologies must function primarily within bioregional patterns and scales. They must maintain biological diversity and environmental integrity contribute to the health of air, water, and soils, incorporate design and construction that reflect bio-regional conditions, and reduce the impacts of human use. Sustainable design, sustainable development, design with nature environmentally sensitive design, holistic resource management - regardless of what it's called, "sustainability," the capability of natural and cultural systems being continued over time, is the key. Sustainable design must use an alternative approach to traditional design and the new design approach must recognize the impacts of every design choice on the natural and cultural resources of the local, regional, and global environments. Sustainable park and recreation development will succeed to the degree that it anticipates and manages human experiences. Interpretation provides the best single tool for shaping experiences and sharing values. By providing an awareness of the environment, values are taught that are

  13. Basic principles of test-negative design in evaluating influenza vaccine effectiveness.

    Science.gov (United States)

    Fukushima, Wakaba; Hirota, Yoshio

    2017-08-24

    Based on the unique characteristics of influenza, the concept of "monitoring" influenza vaccine effectiveness (VE) across the seasons using the same observational study design has been developed. In recent years, there has been a growing number of influenza VE reports using the test-negative design, which can minimize both misclassification of diseases and confounding by health care-seeking behavior. Although the test-negative designs offer considerable advantages, there are some concerns that widespread use of the test-negative design without knowledge of the basic principles of epidemiology could produce invalid findings. In this article, we briefly review the basic concepts of the test-negative design with respect to classic study design such as cohort studies or case-control studies. We also mention selection bias, which may be of concern in some countries where rapid diagnostic testing is frequently used in routine clinical practices, as in Japan. Copyright © 2017. Published by Elsevier Ltd.

  14. Program design of data acquisition in Windows

    International Nuclear Information System (INIS)

    Cai Jianxin; Yan Huawen

    2004-01-01

    Several methods for the design of data acquisition program based on Microsoft Windows are introduced. Then their respective advantages and disadvantages are totally analyzed. At the same time, the data acquisition modes applicable to each method are also pointed out. It is convenient for data acquisition programmers to develop data acquisition systems. (authors)

  15. Quiet engine program flight engine design study

    Science.gov (United States)

    Klapproth, J. F.; Neitzel, R. E.; Seeley, C. T.

    1974-01-01

    The results are presented of a preliminary flight engine design study based on the Quiet Engine Program high-bypass, low-noise turbofan engines. Engine configurations, weight, noise characteristics, and performance over a range of flight conditions typical of a subsonic transport aircraft were considered. High and low tip speed engines in various acoustically treated nacelle configurations were included.

  16. IN QUEST OF TOTAL QUALITY MANAGEMENT PRINCIPLES IN ARCHITECTURAL DESIGN SERVICES: EVIDENCE FROM TURKEY

    Directory of Open Access Journals (Sweden)

    Umut Durmus

    2010-12-01

    Full Text Available Proposal: Architectural design companies increasingly recognize that time spent on management is not at the expense of their production and there are always better ways to organize business. Although architects have long placed a traditional emphasis on quality, quality management is still a new concept for the majority of architectural design companies, which have to organize relatively more complicated operations nowadays to meet their clients’ expectations. This study aims to understand how architectural design companies define quality and explores the extent to which Total Quality Management (TQM principles like continual improvement, employee involvement, customer satisfaction and others can be pertinent in these companies. Adopting a qualitative research strategy, the authors interviewed with the owner-managers of 10 widely-recognized architectural design companies of different size in Istanbul. The results from the content analysis of semi-structured interview data suggest that i TQM principles cannot be directly applied in architectural design companies without an appropriate translation; ii special characteristics of design services are important to explain quality-related perceptions of owner-managers; iii the owner-managers feel the pressure from the changing internal and external environmental conditions, however few of them adopt a systematic and documented approach to quality management. Architectural design offices which aim to establish a quality management system can benefit from this study to understand potential problem areas on their road.

  17. Extending cluster lot quality assurance sampling designs for surveillance programs.

    Science.gov (United States)

    Hund, Lauren; Pagano, Marcello

    2014-07-20

    Lot quality assurance sampling (LQAS) has a long history of applications in industrial quality control. LQAS is frequently used for rapid surveillance in global health settings, with areas classified as poor or acceptable performance on the basis of the binary classification of an indicator. Historically, LQAS surveys have relied on simple random samples from the population; however, implementing two-stage cluster designs for surveillance sampling is often more cost-effective than simple random sampling. By applying survey sampling results to the binary classification procedure, we develop a simple and flexible nonparametric procedure to incorporate clustering effects into the LQAS sample design to appropriately inflate the sample size, accommodating finite numbers of clusters in the population when relevant. We use this framework to then discuss principled selection of survey design parameters in longitudinal surveillance programs. We apply this framework to design surveys to detect rises in malnutrition prevalence in nutrition surveillance programs in Kenya and South Sudan, accounting for clustering within villages. By combining historical information with data from previous surveys, we design surveys to detect spikes in the childhood malnutrition rate. Copyright © 2014 John Wiley & Sons, Ltd.

  18. Object-oriented design and programming with C++ your hands-on guide to C++ programming, with special emphasis on design, testing, and reuse

    CERN Document Server

    Leach, Ronald

    2014-01-01

    Object-Oriented Design and Programming with C++: Your Hands-On Guide to C++ Programming, with Special Emphasis on Design, Testing, and Reuse provides a list of software engineering principles to guide the software development process. This book presents the fundamentals of the C++ language.Organized into two parts encompassing 10 chapters, this book begins with an overview of C++ and describes object-oriented programming and the history of C++. This text then introduces classes, polymorphism, inheritance, and overloading. Other chapters consider the C++ preprocessor and organization of class l

  19. Grounding IS Design Education in the First Principles of a Designerly Way of Knowing

    Science.gov (United States)

    Waguepack, Leslie J.; Babb, Jeffry S.

    2017-01-01

    "The Golden Age of Design may finally be upon us!" or so reported the New York Times in September of 2014. On the one hand everyday personal information appliances emphasized beauty and function. Apple™ took a lead by marketing the "feeling" of the iPod's design. The business world took notice and the cachet of designers soared…

  20. A review of human factors principles for the design and implementation of medication safety alerts in clinical information systems

    OpenAIRE

    Phansalkar, Shobha; Edworthy, Judy; Hellier, Elizabeth; Seger, Diane L; Schedlbauer, Angela; Avery, Anthony J; Bates, David W

    2010-01-01

    The objective of this review is to describe the implementation of human factors principles for the design of alerts in clinical information systems. First, we conduct a review of alarm systems to identify human factors principles that are employed in the design and implementation of alerts. Second, we review the medical informatics literature to provide examples of the implementation of human factors principles in current clinical information systems using alerts to provide medication decisio...

  1. Using engineering control principles to inform the design of adaptive interventions: a conceptual introduction.

    Science.gov (United States)

    Rivera, Daniel E; Pew, Michael D; Collins, Linda M

    2007-05-01

    The goal of this paper is to describe the role that control engineering principles can play in developing and improving the efficacy of adaptive, time-varying interventions. It is demonstrated that adaptive interventions constitute a form of feedback control system in the context of behavioral health. Consequently, drawing from ideas in control engineering has the potential to significantly inform the analysis, design, and implementation of adaptive interventions, leading to improved adherence, better management of limited resources, a reduction of negative effects, and overall more effective interventions. This article illustrates how to express an adaptive intervention in control engineering terms, and how to use this framework in a computer simulation to investigate the anticipated impact of intervention design choices on efficacy. The potential benefits of operationalizing decision rules based on control engineering principles are particularly significant for adaptive interventions that involve multiple components or address co-morbidities, situations that pose significant challenges to conventional clinical practice.

  2. Design Principles for the Atomic and Electronic Structure of Halide Perovskite Photovoltaic Materials: Insights from Computation.

    Science.gov (United States)

    Berger, Robert F

    2018-02-09

    In the current decade, perovskite solar cell research has emerged as a remarkably active, promising, and rapidly developing field. Alongside breakthroughs in synthesis and device engineering, halide perovskite photovoltaic materials have been the subject of predictive and explanatory computational work. In this Minireview, we focus on a subset of this computation: density functional theory (DFT)-based work highlighting the ways in which the electronic structure and band gap of this class of materials can be tuned via changes in atomic structure. We distill this body of computational literature into a set of underlying design principles for the band gap engineering of these materials, and rationalize these principles from the viewpoint of band-edge orbital character. We hope that this perspective provides guidance and insight toward the rational design and continued improvement of perovskite photovoltaics. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. Parallel power electronics filters in three-phase four-wire systems principle, control and design

    CERN Document Server

    Wong, Man-Chung; Lam, Chi-Seng

    2016-01-01

    This book describes parallel power electronic filters for 3-phase 4-wire systems, focusing on the control, design and system operation. It presents the basics of power-electronics techniques applied in power systems as well as the advanced techniques in controlling, implementing and designing parallel power electronics converters. The power-quality compensation has been achieved using active filters and hybrid filters, and circuit models, control principles and operational practice problems have been verified by principle study, simulation and experimental results. The state-of-the-art research findings were mainly developed by a team at the University of Macau. Offering background information and related novel techniques, this book is a valuable resource for electrical engineers and researchers wanting to work on energy saving using power-quality compensators or renewable energy power electronics systems. .

  4. Program Helps Design Tests Of Developmental Software

    Science.gov (United States)

    Hops, Jonathan

    1994-01-01

    Computer program called "A Formal Test Representation Language and Tool for Functional Test Designs" (TRL) provides automatic software tool and formal language used to implement category-partition method and produce specification of test cases in testing phase of development of software. Category-partition method useful in defining input, outputs, and purpose of test-design phase of development and combines benefits of choosing normal cases having error-exposing properties. Traceability maintained quite easily by creating test design for each objective in test plan. Effort to transform test cases into procedures simplified by use of automatic software tool to create cases based on test design. Method enables rapid elimination of undesired test cases from consideration and facilitates review of test designs by peer groups. Written in C language.

  5. Environmental qualification program for new designs

    International Nuclear Information System (INIS)

    Doerffer, K.

    2007-01-01

    Qualification of nuclear power plant equipment and components important to safety (ITS) is an integral part of the design process. The qualification methodology differs based on the severity of service conditions (operational and ambient), to which the ITS equipment is exposed. In Canada, the licensing requirements for environmental qualification for new designs are governed by the Canadian Standard Association (CSA) standard, N290.13-2005 titled 'Environmental Qualification of Equipment for CANDU Nuclear Power Plants' and the pre-consultation draft, 'Requirements for Design of Nuclear Power Plants'(DRD), issued for trial use by the Canadian Nuclear Safety Commission (CNSC) in March 2005. This paper will describe AECL's current Environmental Qualification program developed to comply with the above licensing requirements as applied to new designs. The focus will be given to qualification of ITS systems structures and components (SSC) to harsh conditions occurring due to the Design Basis Accidents (DBA). (author)

  6. Application of Instructional Design Principles in Developing an Online Information Literacy Curriculum.

    Science.gov (United States)

    Mi, Misa

    2016-01-01

    An online information literacy curriculum was developed as an intervention to engage students in independent study and self-assessment of their learning needs and learning outcomes, develop proficiency in information skills, and foster lifelong learning. This column demonstrates how instructional design principles were applied to create the learning experiences integrated into various courses of the medical curriculum to promote active learning of information skills and maximize self-directed learning outcomes for lifelong learning.

  7. The Effect of Content Representation Design Principles on Users' Intuitive Beliefs and Use of E-Learning Systems

    Science.gov (United States)

    Al-Samarraie, Hosam; Selim, Hassan; Zaqout, Fahed

    2016-01-01

    A model is proposed to assess the effect of different content representation design principles on learners' intuitive beliefs about using e-learning. We hypothesized that the impact of the representation of course contents is mediated by the design principles of alignment, quantity, clarity, simplicity, and affordance, which influence the…

  8. Hydride heat pump. Volume I. Users manual for HYCSOS system design program. [HYCSOS code

    Energy Technology Data Exchange (ETDEWEB)

    Gorman, R.; Moritz, P.

    1978-05-01

    A method for the design and costing of a metal hydride heat pump for residential use and a computer program, HYCSOS, which automates that method are described. The system analyzed is one in which a metal hydride heat pump can provide space heating and space cooling powered by energy from solar collectors and electric power generated from solar energy. The principles and basic design of the system are presented, and the computer program is described giving detailed design and performance equations used in the program. The operation of the program is explained, and a sample run is presented. This computer program is part of an effort to design, cost, and evaluate a hydride heat pump for residential use. The computer program is written in standard Fortran IV and was run on a CDC Cyber 74 and Cyber 174 computer. A listing of the program is included as an appendix. This report is Volume 1 of a two-volume document.

  9. Designing nanomaterials to maximize performance and minimize undesirable implications guided by the Principles of Green Chemistry.

    Science.gov (United States)

    Gilbertson, Leanne M; Zimmerman, Julie B; Plata, Desiree L; Hutchison, James E; Anastas, Paul T

    2015-08-21

    The Twelve Principles of Green Chemistry were first published in 1998 and provide a framework that has been adopted not only by chemists, but also by design practitioners and decision-makers (e.g., materials scientists and regulators). The development of the Principles was initially motivated by the need to address decades of unintended environmental pollution and human health impacts from the production and use of hazardous chemicals. Yet, for over a decade now, the Principles have been applied to the synthesis and production of engineered nanomaterials (ENMs) and the products they enable. While the combined efforts of the global scientific community have led to promising advances in the field of nanotechnology, there remain significant research gaps and the opportunity to leverage the potential global economic, societal and environmental benefits of ENMs safely and sustainably. As such, this tutorial review benchmarks the successes to date and identifies critical research gaps to be considered as future opportunities for the community to address. A sustainable material design framework is proposed that emphasizes the importance of establishing structure-property-function (SPF) and structure-property-hazard (SPH) relationships to guide the rational design of ENMs. The goal is to achieve or exceed the functional performance of current materials and the technologies they enable, while minimizing inherent hazard to avoid risk to human health and the environment at all stages of the life cycle.

  10. Development of safety principles for the design of future nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-06-01

    The main purpose of this TECDOC is to propose updates to existing safety principles which could be used as a basis for developing safety principles for the design of future NPPs. Accordingly, this document is intended to be useful to reactor designers, owners, operators, researchers and regulators. It is also expected that this document can contribute to international harmonization of safety approaches, and that it will help ensure that future reactors will be designed worldwide to a high standard of safety. As such, these proposed updates are intended to provide general guidance which, if carefully and properly implemented, will result in reactor designs with enhanced safety characteristics beyond those currently in operation. This enhancement results from the fact that the proposals are derived from the lessons learned from more recent operational experience, R and D, design, testing, and analysis developed over the past decade or so, as well as from attempts to reflect the current trends in reactor design, such as the introduction of new technologies. 8 refs, 3 figs.

  11. Towards automating the discovery of certain innovative design principles through a clustering-based optimization technique

    Science.gov (United States)

    Bandaru, Sunith; Deb, Kalyanmoy

    2011-09-01

    In this article, a methodology is proposed for automatically extracting innovative design principles which make a system or process (subject to conflicting objectives) optimal using its Pareto-optimal dataset. Such 'higher knowledge' would not only help designers to execute the system better, but also enable them to predict how changes in one variable would affect other variables if the system has to retain its optimal behaviour. This in turn would help solve other similar systems with different parameter settings easily without the need to perform a fresh optimization task. The proposed methodology uses a clustering-based optimization technique and is capable of discovering hidden functional relationships between the variables, objective and constraint functions and any other function that the designer wishes to include as a 'basis function'. A number of engineering design problems are considered for which the mathematical structure of these explicit relationships exists and has been revealed by a previous study. A comparison with the multivariate adaptive regression splines (MARS) approach reveals the practicality of the proposed approach due to its ability to find meaningful design principles. The success of this procedure for automated innovization is highly encouraging and indicates its suitability for further development in tackling more complex design scenarios.

  12. Applying design principles to fusion reactor configurations for propulsion in space

    International Nuclear Information System (INIS)

    Carpenter, S.A.; Deveny, M.E.; Schulze, N.R.

    1993-01-01

    The application of fusion power to space propulsion requires rethinking the engineering-design solution to controlled-fusion energy. Whereas the unit cost of electricity (COE) drives the engineering-design solution for utility-based fusion reactor configurations; initial mass to low earth orbit (IMLEO), specific jet power (kW(thrust)/kg(engine)), and reusability drive the engineering-design solution for successful application of fusion power to space propulsion. Three design principles (DP's) were applied to adapt and optimize three candidate-terrestrial-fusion-reactor configurations for propulsion in space. The three design principles are: provide maximum direct access to space for waste radiation, operate components as passive radiators to minimize cooling-system mass, and optimize the plasma fuel, fuel mix, and temperature for best specific jet power. The three candidate terrestrial fusion reactor configurations are: the thermal barrier tandem mirror (TBTM), field reversed mirror (FRM), and levitated dipole field (LDF). The resulting three candidate space fusion propulsion systems have their IMLEO minimized and their specific jet power and reusability maximized. A preliminary rating of these configurations was performed, and it was concluded that the leading engineering-design solution to space fusion propulsion is a modified TBTM that we call the Mirror Fusion Propulsion System (MFPS)

  13. Development of safety principles for the design of future nuclear power plants

    International Nuclear Information System (INIS)

    1995-06-01

    The main purpose of this TECDOC is to propose updates to existing safety principles which could be used as a basis for developing safety principles for the design of future NPPs. Accordingly, this document is intended to be useful to reactor designers, owners, operators, researchers and regulators. It is also expected that this document can contribute to international harmonization of safety approaches, and that it will help ensure that future reactors will be designed worldwide to a high standard of safety. As such, these proposed updates are intended to provide general guidance which, if carefully and properly implemented, will result in reactor designs with enhanced safety characteristics beyond those currently in operation. This enhancement results from the fact that the proposals are derived from the lessons learned from more recent operational experience, R and D, design, testing, and analysis developed over the past decade or so, as well as from attempts to reflect the current trends in reactor design, such as the introduction of new technologies. 8 refs, 3 figs

  14. STRATEGIC PROJECT MANAGEMENT PRINCIPLES, PROGRAMS AND PORTFOLIOS OF THE MEDICAL INSTITUTION

    Directory of Open Access Journals (Sweden)

    Елена Борисовна ДАНЧЕНКО

    2017-03-01

    Full Text Available The article gives a brief overview of the latest research in the direction of the use of the project-based approach to the management of medical institutions. It is shown that medicine today is a project-oriented area, and modern scientific studies suggest the use of not only the project management approach and portfolio management. The various scientific sources proposed the classification of projects of medical institutions, mechanisms of formation of projects portfolios of such institutions. The concept of integrated management of medical institutions, which includes strategic, project, portfolio, program management approach (S3P-concept, is offered. According to this concept, the process of S3P-management of the medical institution will include four stages, which are closely interrelated. For the first time, the pair principles of S3P-management are formulated. The proposed concept and principles of S3P-management of medical institution require further development and creating of models, methods and integrated management tools, as well as the development of a system of indicators verify compliance with the organization's strategy of its projects, projects portfolios and programs. This concept and the proposed integrated management principles are universal and can be applied to any project-oriented area.

  15. Principles for designing proteins with cavities formed by curved β sheets

    Energy Technology Data Exchange (ETDEWEB)

    Marcos, Enrique; Basanta, Benjamin; Chidyausiku, Tamuka M.; Tang, Yuefeng; Oberdorfer, Gustav; Liu, Gaohua; Swapna, G. V. T.; Guan, Rongjin; Silva, Daniel-Adriano; Dou, Jiayi; Pereira, Jose Henrique; Xiao, Rong; Sankaran, Banumathi; Zwart, Peter H.; Montelione, Gaetano T.; Baker, David

    2017-01-12

    Active sites and ligand-binding cavities in native proteins are often formed by curved β sheets, and the ability to control β-sheet curvature would allow design of binding proteins with cavities customized to specific ligands. Toward this end, we investigated the mechanisms controlling β-sheet curvature by studying the geometry of β sheets in naturally occurring protein structures and folding simulations. The principles emerging from this analysis were used to design, de novo, a series of proteins with curved β sheets topped with α helices. Nuclear magnetic resonance and crystal structures of the designs closely match the computational models, showing that β-sheet curvature can be controlled with atomic-level accuracy. Our approach enables the design of proteins with cavities and provides a route to custom design ligand-binding and catalytic sites.

  16. Designing a leadership development program for surgeons.

    Science.gov (United States)

    Jaffe, Gregory A; Pradarelli, Jason C; Lemak, Christy Harris; Mulholland, Michael W; Dimick, Justin B

    2016-01-01

    Although numerous leadership development programs (LDPs) exist in health care, no programs have been specifically designed to meet the needs of surgeons. This study aimed to elicit practicing surgeons' motivations and desired goals for leadership training to design an evidence-based LDP in surgery. At a large academic health center, we conducted semistructured interviews with 24 surgical faculty members who voluntarily applied and were selected for participation in a newly created LDP. Transcriptions of the interviews were analyzed using analyst triangulation and thematic coding to extract major themes regarding surgeons' motivations and perceived needs for leadership knowledge and skills. Themes from interview responses were then used to design the program curriculum specifically to meet the leadership needs of surgical faculty. Three major themes emerged regarding surgeons' motivations for seeking leadership training: (1) Recognizing key gaps in their formal preparation for leadership roles; (2) Exhibiting an appetite for personal self-improvement; and (3) Seeking leadership guidance for career advancement. Participants' interviews revealed four specific domains of knowledge and skills that they indicated as desired takeaways from a LDP: (1) leadership and communication; (2) team building; (3) business acumen/finance; and (4) greater understanding of the health care context. Interviews with surgical faculty members identified gaps in prior leadership training and demonstrated concrete motivations and specific goals for participating in a formal leadership program. A LDP that is specifically tailored to address the needs of surgical faculty may benefit surgeons at a personal and institutional level. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. Roots of Performance - Aided Design in Utzon´s design principles

    DEFF Research Database (Denmark)

    Parigi, Dario

    2014-01-01

    on paper, to an evolving paradigm where the increasing integration of parametric tools, performative analysis and computational methods is changing the way we learn and design. Its constitutive factors are: 1) embedded tectonics, 2) performance simulation 3) computational methods.......This paper discuss an emerging paradigm here identified as PAD, acronym of Performance-Aided Design, that aims at embracing complexity in the design process, and tackling it with digital tools. Computer Aided Design tools are gradually shifting from the mere translation of the work once carried...

  18. Design criteria for piping and nozzles program

    International Nuclear Information System (INIS)

    Moore, S.E.; Bryson, J.W.

    1977-01-01

    This report reviews the activities and accomplishments of the Design Criteria for Piping and Nozzles program being conducted by the Oak Ridge National Laboratory for the period July 1, 1975, to September 30, 1976. The objectives of the program are to conduct integrated experimental and analytical stress analysis studies of piping system components and isolated and closely-spaced pressure vessel nozzles in order to confirm and/or improve the adequacy of structural design criteria and analytical methods used to assure the safe design of nuclear power plants. Activities this year included the development of a finite-element program for analyzing two closely spaced nozzles in a cylindrical pressure vessel; a limited-parameter study of vessels with isolated nozzles, finite-element studies of piping elbows, a fatigue test of an out-of-round elbow, summary and evaluation of experimental studies on the elastic-response and fatigue failure of tees, parameter studies on the behavior of flanged joints, publication of fifteen topical reports and papers on various experimental and analytical studies; and the development and acceptance of a number of design rules changes to the ASME Code. 2 figures, 2 tables

  19. Control room philosophy: Principles of control room design and control room work

    International Nuclear Information System (INIS)

    Skriver, Jan; Ramberg, Jasmine; Allwin, Pernilla

    2006-01-01

    In order to provide insights for improvement of work in control rooms several factors have to be considered. Knowledge of principles including control room philosophies will guide the recommended improvements. In addition to knowledge about specific principles an advantage for an organization can be an understanding of similarities and policies used in other high risk industry. The report has been developed on the basis of a document analysis of international standards and other guiding documents. (NUREG 0711, ISO 11064, ISO 6385, IEC 60964). In addition to the document analysis which has strived to compare the documents to see similarities in important principals, experience from working with control room design, modifications and evaluations in other high risk industries has pervaded the report. Important principles have been identified which are recommended to be included in a control room philosophy. Many of these are similar to the principles identified in the international standards. An additional principal which is regarded as important is the utilization of Key Performance Indicators (KPI) which can be used as a measure to target preventative means. Further more it is critical that the control room philosophy is easy to access and comprehend for all users. One of the challenges that remain after having developed a control room philosophy is how to utilize it in the daily work situation. It is vital that the document remains as a living document, guiding the continual improvement of the control room in the various life cycle stages

  20. Designation and Implementation of Microcomputer Principle and Interface Technology Virtual Experimental Platform Website

    Science.gov (United States)

    Gao, JinYue; Tang, Yin

    This paper explicitly discusses the designation and implementation thought and method of Microcomputer Principle and Interface Technology virtual experimental platform website construction. The instructional design of this platform mainly follows with the students-oriented constructivism learning theory, and the overall structure is subject to the features of teaching aims, teaching contents and interactive methods. Virtual experiment platform production and development should fully take the characteristics of network operation into consideration and adopt relevant technologies to improve the effect and speed of network software application in internet.

  1. Code of practice and design principles for portable and transportable radiological protection systems

    International Nuclear Information System (INIS)

    Wells, F.H.; Powell, R.G.

    1980-10-01

    The Code of Practice and design principles for portable and transportable radiological protection systems are presented in three parts. Part 1 specifies the requirement for Radiological Protection Instrumentation (RPI) including operational characteristics and the effects of both a radiation and non-radiation environment. Part 2 satisfies the requirement for RPI equipment as regards the overall design, the availability, the reliability, the information display, the human factors, the power supplies, the manufacture and quality assurance, the testing and the cost. Part 3 deals with the supply, location and operation of the RPI equipment. (U.K.)

  2. Safety philosophy and design principles for systems and components of nuclear power plant: external event

    International Nuclear Information System (INIS)

    Lopes, J.P.G.

    1986-01-01

    In nuclear power plants, some systems and components are designed to withstand external impacts. Such systems and components are those which have to perform their functions even during and after the occurrences of an earthquake, for example, fulfilling the safety objectives and avoiding the release of radioactive material to the environment. The aim of this report is to introduce the safety philosophy and design principles for systems/components to perform their functions during and after the occurrence of an earthquake, as applied by NUCLEN for Angra 2 and 3. (Author) [pt

  3. Computational Materials Program for Alloy Design

    Science.gov (United States)

    Bozzolo, Guillermo

    2005-01-01

    The research program sponsored by this grant, "Computational Materials Program for Alloy Design", covers a period of time of enormous change in the emerging field of computational materials science. The computational materials program started with the development of the BFS method for alloys, a quantum approximate method for atomistic analysis of alloys specifically tailored to effectively deal with the current challenges in the area of atomistic modeling and to support modern experimental programs. During the grant period, the program benefited from steady growth which, as detailed below, far exceeds its original set of goals and objectives. Not surprisingly, by the end of this grant, the methodology and the computational materials program became an established force in the materials communitiy, with substantial impact in several areas. Major achievements during the duration of the grant include the completion of a Level 1 Milestone for the HITEMP program at NASA Glenn, consisting of the planning, development and organization of an international conference held at the Ohio Aerospace Institute in August of 2002, finalizing a period of rapid insertion of the methodology in the research community worlwide. The conference, attended by citizens of 17 countries representing various fields of the research community, resulted in a special issue of the leading journal in the area of applied surface science. Another element of the Level 1 Milestone was the presentation of the first version of the Alloy Design Workbench software package, currently known as "adwTools". This software package constitutes the first PC-based piece of software for atomistic simulations for both solid alloys and surfaces in the market.Dissemination of results and insertion in the materials community worldwide was a primary focus during this period. As a result, the P.I. was responsible for presenting 37 contributed talks, 19 invited talks, and publishing 71 articles in peer-reviewed journals, as

  4. [Design of an HACCP program for a cocoa processing facility].

    Science.gov (United States)

    López D'Sola, Patrizia; Sandia, María Gabriela; Bou Rached, Lizet; Hernández Serrano, Pilar

    2012-12-01

    The HACCP plan is a food safety management tool used to control physical, chemical and biological hazards associated to food processing through all the processing chain. The aim of this work is to design a HACCP Plan for a Venezuelan cocoa processing facility.The production of safe food products requires that the HACCP system be built upon a solid foundation of prerequisite programs such as Good Manufacturing Practices (GMP) and Sanitation Standard Operating Procedures (SSOP). The existence and effectiveness of these prerequisite programs were previously assessed.Good Agriculture Practices (GAP) audit to cocoa nibs suppliers were performed. To develop the HACCP plan, the five preliminary tasks and the seven HACCP principles were accomplished according to Codex Alimentarius procedures. Three Critical Control Points (CCP) were identified using a decision tree: winnowing (control of ochratoxin A), roasting (Salmonella control) and metallic particles detection. For each CCP, Critical limits were established, the Monitoring procedures, Corrective actions, Procedures for Verification and Documentation concerning all procedures and records appropriate to these principles and their application was established. To implement and maintain a HACCP plan for this processing plant is suggested. Recently OchratoxinA (OTA) has been related to cocoa beans. Although the shell separation from the nib has been reported as an effective measure to control this chemical hazard, ochratoxin prevalence study in cocoa beans produced in the country is recommended, and validate the winnowing step as well

  5. NRC Seismic Design Margins Program Plan

    International Nuclear Information System (INIS)

    Cummings, G.E.; Johnson, J.J.; Budnitz, R.J.

    1985-08-01

    Recent studies estimate that seismically induced core melt comes mainly from earthquakes in the peak ground acceleration range from 2 to 4 times the safe shutdown earthquake (SSE) acceleration used in plant design. However, from the licensing perspective of the US Nuclear Regulatory Commission, there is a continuing need for consideration of the inherent quantitative seismic margins because of, among other things, the changing perceptions of the seismic hazard. This paper discusses a Seismic Design Margins Program Plan, developed under the auspices of the US NRC, that provides the technical basis for assessing the significance of design margins in terms of overall plant safety. The Plan will also identify potential weaknesses that might have to be addressed, and will recommend technical methods for assessing margins at existing plants. For the purposes of this program, a general definition of seismic design margin is expressed in terms of how much larger that the design basis earthquake an earthquake must be to compromise plant safety. In this context, margin needs to be determined at the plant, system/function, structure, and component levels. 14 refs., 1 fig

  6. Large coil program support structure conceptual design

    International Nuclear Information System (INIS)

    Litherland, P.S.

    1977-01-01

    The purpose of the Large Coil Program (LCP) is to perform tests on both pool boiling and force cooled superconducting toroidal field coils. The tests will attempt to approximate conditions anticipated in an ignition tokamak. The test requirements resulted in a coil support design which accommodates up to six (6) test coils and is mounted to a structure capable of resisting coil interactions. The steps leading to the present LCP coil support structure design, details on selected structural components, and the basic assembly sequence are discussed

  7. Heuristic program to design Relational Databases

    Directory of Open Access Journals (Sweden)

    Manuel Pereira Rosa

    2009-09-01

    Full Text Available The great development of today’s world determines that the world level of information increases day after day, however, the time allowed to transmit this information in the classrooms has not changed. Thus, the rational work in this respect is more than necessary. Besides, if for the solution of a given type of problem we do not have a working algorism, we have, first to look for a correct solution, then the heuristic programs are of paramount importance to succeed in these aspects. Having into consideration that the design of the database is, essentially, a process of problem resolution, this article aims at proposing a heuristic program for the design of the relating database.

  8. Advanced network programming principles and techniques : network application programming with Java

    CERN Document Server

    Ciubotaru, Bogdan

    2013-01-01

    Answering the need for an accessible overview of the field, this text/reference presents a manageable introduction to both the theoretical and practical aspects of computer networks and network programming. Clearly structured and easy to follow, the book describes cutting-edge developments in network architectures, communication protocols, and programming techniques and models, supported by code examples for hands-on practice with creating network-based applications. Features: presents detailed coverage of network architectures; gently introduces the reader to the basic ideas underpinning comp

  9. Human Factors Principles in Design of Computer-Mediated Visualization for Robot Missions

    Energy Technology Data Exchange (ETDEWEB)

    David I Gertman; David J Bruemmer

    2008-12-01

    With increased use of robots as a resource in missions supporting countermine, improvised explosive devices (IEDs), and chemical, biological, radiological nuclear and conventional explosives (CBRNE), fully understanding the best means by which to complement the human operator’s underlying perceptual and cognitive processes could not be more important. Consistent with control and display integration practices in many other high technology computer-supported applications, current robotic design practices rely highly upon static guidelines and design heuristics that reflect the expertise and experience of the individual designer. In order to use what we know about human factors (HF) to drive human robot interaction (HRI) design, this paper reviews underlying human perception and cognition principles and shows how they were applied to a threat detection domain.

  10. Thermal hydraulics and mechanics core design programs

    International Nuclear Information System (INIS)

    Heinecke, J.

    1992-10-01

    The report documents the work performed within the Research and Development Task T hermal hydraulics and mechanics core design programs , funded by the German government. It contains the development of new codes, the extension of existing codes, the qualification and verification of codes and the development of a code library. The overall goal of this work was to adapt the system of thermal hydraulics and mechanics codes to the permanently growing requirements of the status of science and technology

  11. Incorporating person centred care principles into an ongoing comprehensive cancer management program: An experiential account

    Directory of Open Access Journals (Sweden)

    Vallath Nandini

    2011-01-01

    Full Text Available Recent research indicates a definite positive impact on treatment outcomes when an integrative approach that focuses on symptom control and quality of life is provided along with the standard therapeutic regimens. However implementation or practice of this approach is not seen widely due to the culture of medical training and practice. This article presents the initial development of a program for incorporating integrative care principles into an ongoing comprehensive cancer care program at a tertiary centre. The key purpose of the program being to develop, facilitate, and establish comprehensive and holistic processes including palliative care principles, that would positively enhance the quantity and quality of life of the person with disease, as well as create an environment that reflects and sustains this approach. The vision, objectives, goals, strategies, activities and results within the 7 months of implementation are documented. The new learnings gained during the process have also been noted in the hope that the model described may be used to conceptualize similar care giving facilities in other centres.

  12. Intentional Teaching, Intentional Scholarship: Applying Backward Design Principles in a Faculty Writing Group

    Science.gov (United States)

    Linder, Kathryn E.; Cooper, Frank Rudy; McKenzie, Elizabeth M.; Raesch, Monika; Reeve, Patricia A.

    2014-01-01

    Backward design is a course creation method that encourages teachers to identify their goals for student understanding and measurable objectives for learning from the outset. In this article we explore the application of backward design to the production of scholarly articles. Specifically, we report on a writing group program that encourages…

  13. Java programming fundamentals problem solving through object oriented analysis and design

    CERN Document Server

    Nair, Premchand S

    2008-01-01

    While Java texts are plentiful, it's difficult to find one that takes a real-world approach, and encourages novice programmers to build on their Java skills through practical exercise. Written by an expert with 19 experience teaching computer programming, Java Programming Fundamentals presents object-oriented programming by employing examples taken from everyday life. Provides a foundation in object-oriented design principles and UML notation Describes common pitfalls and good programming practicesFurnishes supplemental links, documents, and programs on its companion website, www.premnair.netU

  14. How nature designs light-harvesting antenna systems: design principles and functional realization in chlorophototrophic prokaryotes

    Science.gov (United States)

    Bryant, Donald A.; Canniffe, Daniel P.

    2018-02-01

    Chlorophyll-based phototrophs, or chlorophototrophs, convert light energy into stored chemical potential energy using two types of photochemical reaction center (RC), denoted type-1 and type-2. After excitation with light, a so-called special pair of chlorophylls in the RC is oxidized, and an acceptor is reduced. To ensure that RCs function at maximal rates in diffuse and variable light conditions, chlorophototrophs have independently evolved diverse light-harvesting antenna systems to rapidly and efficiently transfer that energy to the RCs. Energy transfer between weakly coupled chromophores is generally believed to proceed by resonance energy transfer, a dipole-induced-dipole process that was initially described theoretically by Förster. Nature principally optimizes three parameters in antenna systems: the distance separating the donor and acceptor chromophores, the relative orientations of those chromophores, and the spectral overlap between the donor and the acceptor chromophores. However, there are other important biological parameters that nature has optimized, and some common themes emerge from comparisons of different antenna systems. This tutorial considers structural and functional characteristics of three fundamentally different light-harvesting antenna systems of chlorophotrophic bacteria: phycobilisomes of cyanobacteria, the light-harvesting complexes (LH1 and LH2) of purple bacteria, and chlorosomes of green bacteria. Phycobilisomes are generally considered to represent an antenna system in which the chromophores are weakly coupled, while the strongly coupled bacteriochlorophyll molecules in LH1 and LH2 are strongly coupled and are better described by exciton theory. Chlorosomes can contain up to 250 000 bacteriochlorophyll molecules, which are very strongly coupled and form supramolecular, nanotubular arrays. The general and specific principles that have been optimized by natural selection during the evolution of these diverse light

  15. Design Principles for Rapid Prototyping Forces Sensors using 3D Printing.

    Science.gov (United States)

    Kesner, Samuel B; Howe, Robert D

    2011-07-21

    Force sensors provide critical information for robot manipulators, manufacturing processes, and haptic interfaces. Commercial force sensors, however, are generally not adapted to specific system requirements, resulting in sensors with excess size, cost, and fragility. To overcome these issues, 3D printers can be used to create components for the quick and inexpensive development of force sensors. Limitations of this rapid prototyping technology, however, require specialized design principles. In this paper, we discuss techniques for rapidly developing simple force sensors, including selecting and attaching metal flexures, using inexpensive and simple displacement transducers, and 3D printing features to aid in assembly. These design methods are illustrated through the design and fabrication of a miniature force sensor for the tip of a robotic catheter system. The resulting force sensor prototype can measure forces with an accuracy of as low as 2% of the 10 N measurement range.

  16. A review of human factors principles for the design and implementation of medication safety alerts in clinical information systems.

    Science.gov (United States)

    Phansalkar, Shobha; Edworthy, Judy; Hellier, Elizabeth; Seger, Diane L; Schedlbauer, Angela; Avery, Anthony J; Bates, David W

    2010-01-01

    The objective of this review is to describe the implementation of human factors principles for the design of alerts in clinical information systems. First, we conduct a review of alarm systems to identify human factors principles that are employed in the design and implementation of alerts. Second, we review the medical informatics literature to provide examples of the implementation of human factors principles in current clinical information systems using alerts to provide medication decision support. Last, we suggest actionable recommendations for delivering effective clinical decision support using alerts. A review of studies from the medical informatics literature suggests that many basic human factors principles are not followed, possibly contributing to the lack of acceptance of alerts in clinical information systems. We evaluate the limitations of current alerting philosophies and provide recommendations for improving acceptance of alerts by incorporating human factors principles in their design.

  17. Principles relating to the digital instrumentation and control design approach 2017

    International Nuclear Information System (INIS)

    2017-01-01

    The design of the instrumentation and control of nuclear facilities uses digital systems that offer increasing computation and interconnection capabilities. They enable advanced functions to be carried out, such as calculation of the critical heat flux ratio, help to detect hardware failures in real time and provide operators with rich, flexible interfaces. However, these evolved functions may be affected by faults that make their logic systematically inadequate in certain cases, which introduces sources of failure other than random hardware failures and raises questions about the informal concept of the increased 'complexity' of instrumentation and control. Appropriate design principles shall therefore be applied so that this logic is as fault-free as possible and can be assessed by an independent body such as IRSN. This document presents the main problems associated with the design of the digital instrumentation and control of a complex facility, as well as the general principles to follow to demonstrate that a satisfactory safety level has been achieved. The doctrine elements presented in this document are the result of the experience acquired during assessments carried out for the French nuclear power plants, enhanced by exchanges with experts from the nuclear sector, and reflect French practice; they apply in other sectors in which a high level of confidence can be attributed to instrumentation and control. The normative texts cited in this document provide detailed requirements that are open to considerable interpretation, as the nature of the problem posed does not enable relevant and measurable criteria to be defined in all cases. This document aims to explain the principles underlying these detailed requirements and to give the means for interpreting them in each situation. (authors)

  18. Design and evaluation of potentiometric principles for bladder volume monitoring: a preliminary study.

    Science.gov (United States)

    Chen, Shih-Ching; Hsieh, Tsung-Hsun; Fan, Wen-Jia; Lai, Chien-Hung; Chen, Chun-Lung; Wei, Wei-Feng; Peng, Chih-Wei

    2015-06-01

    Recent advances in microelectronics and wireless transmission technology have led to the development of various implantable sensors for real-time monitoring of bladder conditions. Although various sensing approaches for monitoring bladder conditions were reported, most such sensors have remained at the laboratory stage due to the existence of vital drawbacks. In the present study, we explored a new concept for monitoring the bladder capacity on the basis of potentiometric principles. A prototype of a potentiometer module was designed and fabricated and integrated with a commercial wireless transmission module and power unit. A series of in vitro pig bladder experiments was conducted to determine the best design parameters for implementing the prototype potentiometric device and to prove its feasibility. We successfully implemented the potentiometric module in a pig bladder model in vitro, and the error of the accuracy of bladder volume detection was design principles and animal experience gathered from this research can serve as a basis for developing new implantable bladder sensors in the future.

  19. Towards Synergistic Electrode-Electrolyte Design Principles for Nonaqueous Li-O[Formula: see text] batteries.

    Science.gov (United States)

    Khetan, Abhishek; Krishnamurthy, Dilip; Viswanathan, Venkatasubramanian

    2018-03-20

    One route toward sustainable land and aerial transportation is based on electrified vehicles. To enable electrification in transportation, there is a need for high-energy-density batteries, and this has led to an enormous interest in lithium-oxygen batteries. Several critical challenges remain with respect to realizing a practical lithium-oxygen battery. In this article, we present a detailed overview of theoretical efforts to formulate design principles for identifying stable electrolytes and electrodes with the desired functionality and stability. We discuss design principles relating to electrolytes and the additional stability challenges that arise at the cathode-electrolyte interface. Based on a thermodynamic analysis, we discuss two important requirements for the cathode: the ability to nucleate the desired discharge product, Li[Formula: see text]O[Formula: see text], and the ability to selectively activate only this discharge product while suppressing lithium oxide, the undesired secondary discharge product. We propose preliminary guidelines for determining the chemical stability of the electrode and illustrate the challenge associated with electrode selection using the examples of carbon cathodes and transition metals. We believe that a synergistic design framework for identifying electrolyte-electrode formulations is needed to realize a practical Li-O[Formula: see text] battery.

  20. Design principles and issues of rights expression languages for digital rights management

    Science.gov (United States)

    Wang, Xin

    2005-07-01

    Digital rights management (DRM) provides a unified approach to specifying, interpreting, enforcing and managing digital rights throughout the entire life cycle of digital assets. Using a declarative rights expression language (REL) for specifying rights and conditions in the form of licenses, as opposite to some other approaches (such as data structures and imperative languages), has been considered and adopted as a superior technology for implementing effective, interoperable and scalable DRM systems. This paper discusses some principles and issues for designing RELs, based on the experiences of developing a family of REL"s (DPRL, XrML 1.x, XrML 2.0 and MPEG REL). It starts with an overview of a family tree of the past and current REL"s, and their development history, followed by an analysis of their data models and a comparison with access-control oriented models. It then presents a number of primary design principles such as syntactic and semantic un-ambiguity, system interoperability, expressiveness in supporting business models and future extensibility, and discusses a number of key design issues such as maintaining stateful information, multi-tier issuance of rights, meta rights, identification of individual and aggregate objects, late-binding of to-beidentified entities, as well as some advanced ones on revocation and delegation of rights. The paper concludes with some remarks on REL profiling and extension for specific application domains.

  1. A game plan: Gamification design principles in mHealth applications for chronic disease management.

    Science.gov (United States)

    Miller, Aaron S; Cafazzo, Joseph A; Seto, Emily

    2016-06-01

    Effective chronic disease management is essential to improve positive health outcomes, and incentive strategies are useful in promoting self-care with longevity. Gamification, applied with mHealth (mobile health) applications, has the potential to better facilitate patient self-management. This review article addresses a knowledge gap around the effective use of gamification design principles, or mechanics, in developing mHealth applications. Badges, leaderboards, points and levels, challenges and quests, social engagement loops, and onboarding are mechanics that comprise gamification. These mechanics are defined and explained from a design and development perspective. Health and fitness applications with gamification mechanics include: bant which uses points, levels, and social engagement, mySugr which uses challenges and quests, RunKeeper which uses leaderboards as well as social engagement loops and onboarding, Fitocracy which uses badges, and Mango Health, which uses points and levels. Specific design considerations are explored, an example of the efficacy of a gamified mHealth implementation in facilitating improved self-management is provided, limitations to this work are discussed, a link between the principles of gaming and gamification in health and wellness technologies is provided, and suggestions for future work are made. We conclude that gamification could be leveraged in developing applications with the potential to better facilitate self-management in persons with chronic conditions. © The Author(s) 2014.

  2. PRINCIPLES OF DESIGNING THE CENTER FOR ADMINISTRATIVE SERVICES IN DNIPROPETROVS’K

    Directory of Open Access Journals (Sweden)

    PODOLYNNY S. I.

    2016-01-01

    Full Text Available Problem. Nowadays providing administrative services of good quality is considered to be one of the most important conditions for establishing firm and democratic relations between local authorities and population The work for creating municipal institutions using the principle of a "single window" is being fulfilled in Dnipropetrovs’k. Two pilot projects have been done at the Department of Architectural Engineering and Design (Prydniprovs’ka State Academy of Construction and Architecture. Objective. To demonstrate peculiarities of two project proposals for CAS comparing them with the recommendations of State Administration and basic principles formed while designing similar objects in foreign practice. Main part. Basic principles for creating the Center for Administrative Services (CAS were formulated regarding foreign experience and recommendations of State Administration. These principles are organized as three conceptual blocks: city-planning relevancy, functional arrangement, form making and artistic image peculiarities. CAS on the left bank of the river is situated on the territory that is being reconstructed at the moment. It is a functional and compositional landmark of social and administrative subcentre of the left bank. The Centre is designed in a 16-storey building with a build-in and build-on 2-floor block of the front-office. The front-office is designed for 121 working places and the back-office – for 440 ones. The general area of the front-office is 605 sq. m., the area of the back-office is 2130 sq. m. Artistic characteristics are designed according to traditional office planning schemes. CAS of the right bank is planned on a vacant site on Zaporiz’ke highway. Spacious parking lots are also provided on the territory. The building is positioned sideways on to the highway with its long axis. It can serve as a peculiar sign at the entrance to the city. The front-office is situated in a two-floor stylobate of the Center

  3. A methodology to aid in the design of naval steels: Linking first principles calculations to mesoscale modeling

    International Nuclear Information System (INIS)

    Spanos, G.; Geltmacher, A.B.; Lewis, A.C.; Bingert, J.F.; Mehl, M.; Papaconstantopoulos, D.; Mishin, Y.; Gupta, A.; Matic, P.

    2007-01-01

    This paper provides a brief overview of a multidisciplinary effort at the Naval Research Laboratory aimed at developing a computationally-based methodology to assist in the design of advanced Naval steels. This program uses multiple computational techniques ranging from the atomistic length scale to continuum response. First-principles electronic structure calculations using density functional theory were employed, semi-empirical angular dependent potentials were developed based on the embedded atom method, and these potentials were used as input into Monte-Carlo and molecular dynamics simulations. Experimental techniques have also been applied to a super-austenitic stainless steel (AL6XN) to provide experimental input, guidance, verification, and enhancements to the models. These experimental methods include optical microscopy, scanning electron microscopy, transmission electron microscopy, electron backscatter diffraction, and serial sectioning in conjunction with computer-based three-dimensional reconstruction and quantitative analyses. The experimental results are also used as critical input into mesoscale finite element models of materials response

  4. The hybrid K-edge/K-XRF densitometer: Principles - design - performance

    International Nuclear Information System (INIS)

    Ottmar, H.; Eberle, H.

    1991-02-01

    The Euratom Safeguards Directorate (ESD) has recently installed a hybrid K-edge/K-XRF densitometer in a commerical reprocessing plant for the safeguarding of nuclear materials. This instrument, developed at KfK Karlsruhe, offers for the first time analytical measurement capabilities for timely on-site input accountancy verification. Lectures providing informations on measurement principles, instrument design features and performance data have been given to inspectors of ESD to make them familiar with the new instrument. This report summarizes the essential materials presented during these courses. (orig.) [de

  5. From First Principles Design to Realization of Bimetallic Catalysts for Enhanced Selectivity

    Energy Technology Data Exchange (ETDEWEB)

    Lobo, Raul F.; Crooks, Richard M.; Mavrikakis, Manos

    2014-04-08

    “Catalysis by design” has been a dream for decades. To specify the composition and structure of matter to effect a desired catalytic transformation with desired and predicted rate and selectivity remains a monumental challenge, especially in heterogeneous catalysis. Our research thrusts have been chosen not only for their practical and scientific relevance, e.g. for more efficient and sustainable chemicals and fuels production, but also because they provide a foundation for developing and exploring broadly applicable principles and strategies for catalyst design.

  6. Designing a 'neotissue' using the principles of biology, chemistry and engineering.

    Science.gov (United States)

    Nannaparaju, Madhusudhan; Oragui, Emeka; Khan, Wasim S

    2012-01-01

    The traditional methods of treating musculoskeletal injuries and disorders are not completely effective and have several limitations. Tissue engineering involves using the principles of biology, chemistry and engineering to design a 'neotissue' that augments a malfunctioning in vivo tissue. The main requirements for functional engineered tissue include reparative cellular components that proliferate on a scaffold grown within a bioreactor that provides specific biochemical and physical signals to regulate cell differentiation and tissue assembly. In this review we provide an overview of the biology of common musculoskeletal tissue and discuss their common pathologies. We also describe the commonly used stem cells, scaffolds and bioreactors and evaluate their role in issue engineering.

  7. Design of an internal dosimetry program

    International Nuclear Information System (INIS)

    Wu, C.F.; Goff, T.E.

    2004-01-01

    Measurement of radiation dose is an essential element of radiation protection programs at nuclear facilities. To protect workers and demonstrate compliance with regulatory requirements, dosimetry programs must be established based on sound technical basis. Historically, external exposure was controlled by occupational dose limits. Internal exposure to radionuclides was limited by maximum permissible body burden and maximum permissible concentration. With the issuance of ICRP 26, ICRP 30, DOE Order 5480.11, DOE/EH-0256T, and the new 10 CFR 20, it has become a requirement that internal dose be assessed and the sum of internal and external doses be maintained below regulatory limits. Nuclear facilities are required to have internal dose evaluation programs adequate to demonstrate compliance with radiation protection standards (RPSs). The Waste Isolation Pilot Plant is a DOE facility designed to demonstrate safe disposal of transuranic (TRU) wastes in an ancient salt bed 2,150 feet underground. Internal dose measurement is required to support waste handling activities. This paper describes the technical basis for the WIPP Internal Dosimetry Program. (author)

  8. 41 CFR 102-76.55 - What sustainable development principles must Federal agencies apply to the siting, design, and...

    Science.gov (United States)

    2010-07-01

    ... and Construction Sustainable Development § 102-76.55 What sustainable development principles must... Acquisition,” Federal agencies must apply sustainable development principles to the siting, design, and... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What sustainable...

  9. Design and analysis of environmental monitoring programs

    DEFF Research Database (Denmark)

    Lophaven, Søren Nymand

    2005-01-01

    This thesis describes statistical methods for modelling space-time phenomena. The methods were applied to data from the Danish marine monitoring program in the Kattegat, measured in the five-year period 1993-1997. The proposed model approaches are characterised as relatively simple methods, which...... into account. Thus, it serves as a compromise between existing methods. The space-time model approaches and geostatistical design methods used in this thesis are generally applicable, i.e. with minor modifications they could equally well be applied within areas such as soil and air pollution. In Danish: Denne...

  10. Instructional Design of a Programming Course

    DEFF Research Database (Denmark)

    Caspersen, Michael Edelgaard; Bennedsen, Jens

    2007-01-01

    We present a brief overview of a model for the human cognitive architecture and three learning theories based on this model: cognitive load theory, cognitive apprenticeship, and worked examples (a key area of cognitive skill acquisition). Based on this brief overview we argue how an introductory...... object-oriented programming course is designed according to results of cognitive science and educational psychology in general and cognitive load theory and cognitive skill acquisition in particular; the principal techniques applied are: worked examples, scaffolding, faded guidance, cognitive...

  11. Robust Control Design via Linear Programming

    Science.gov (United States)

    Keel, L. H.; Bhattacharyya, S. P.

    1998-01-01

    This paper deals with the problem of synthesizing or designing a feedback controller of fixed dynamic order. The closed loop specifications considered here are given in terms of a target performance vector representing a desired set of closed loop transfer functions connecting various signals. In general these point targets are unattainable with a fixed order controller. By enlarging the target from a fixed point set to an interval set the solvability conditions with a fixed order controller are relaxed and a solution is more easily enabled. Results from the parametric robust control literature can be used to design the interval target family so that the performance deterioration is acceptable, even when plant uncertainty is present. It is shown that it is possible to devise a computationally simple linear programming approach that attempts to meet the desired closed loop specifications.

  12. Cardinal principle and application practice of 3D digital model design for nuclear power plant

    International Nuclear Information System (INIS)

    Wang Ruobing; Wu Yan

    2005-01-01

    The practical application of 3D digital model design at nuclear power plants was introduced in detail in the paper. The whole process for system choice, program constitution, model design and project practice were also summarized. By demonstrating the cardinal principal and application practice of 3D digital model design as an important sub-project of CGNPC Digital Plant, the paper validates the rationality and validity of the major architecture system and program configuration of the digital plant, carries out beneficial attempt and study in the overall power plant life engineering management and site practice, and has achieved significant engineering and social benefits. The success of practices in the project accelerates the extended and extensive application of Digital Plant in the operation and maintenance simulation of Daya Bay and Ling'ao Nuclear Power Plants, and the engineering design management for Ling'ao II and III of CGNPC on a consolidated basis. (authors)

  13. Towards Rational Design of Functional Fluoride and Oxyfluoride Materials from First Principles

    Science.gov (United States)

    Charles, Nenian

    Complex transition metal compounds (TMCs) research has produced functional materials with a range of properties, including ferroelectricity, colossal magnetoresistance, nonlinear optical activity and high-temperature superconductivity. Conventional routes to tune properties in transition metal oxides, for example, have relied primarily on cation chemical substitution and interfacial effects in thin film heterostructures. In heteroanionic TMCs, exhibiting two chemically distinct anions coordinating the same or different cations, engineering of the anion sub-lattice for property control is a promising alternative approach. The presence of multiple anions provides additional design variables, such as anion order, that are absent in homoanionic counterparts. The more complex structural and chemical phase space of heteroanionic materials provides a unique opportunity to realize enhanced or unanticipated electronic, optical, and magnetic responses. Although there is growing interest in heteroanionic materials, and synthetic and characterization advances are occurring for these materials, the crystal-chemistry principles for realizing structural and property control are only slowing emerging. This dissertation employs anion engineering to investigate phenomena in transition metal fluorides and oxyfluorides compounds using first principles density functional theory calculations. Oxyfluorides are particularly intriguing owing their tendency to stabilize highly ordered anion sublattices as well as the potential to combine the advantageous properties of transition metal oxides and fluorides. This work 1) addresses the challenges of studying fluorides and oxyfluorides using first principles calculations; 2) evaluates the feasibility of using external stimuli, such as epitaxial strain and hydrostatic pressure, to control properties of fluorides and oxyfluorides; and 3) formulates a computational workflow based on multiple levels of theory and computation to elucidate structure

  14. Studies on design principles and criteria of fuels and graphites for experimental multi-purpose very high temperature reactor

    International Nuclear Information System (INIS)

    Arai, Taketoshi; Sato, Sadao; Tani, Yutaro

    1977-12-01

    Design principles and criteria of fuels and graphites have been studied to determine the main design parameters of a reference core MARK-III of the Experimental Multi-purpose Very High Temperature Reactor. The present status of research and development for HTGR fuels and graphites is reviewed from a standpoint of their integrity and safety aspects, and is compared to the specific design requirements for the VHTR fuels and graphites. Consequently, reasonable materials specifications, safety criteria and design analysis methods are presented for coated fuel particle, fuel compact, graphite sleeve, core support graphite and neutron absorber material. These design principles and criteria will be refined by further experimental investigations. (auth.)

  15. Investigations into the design principles in the chemotactic behavior of Escherichia coli.

    Science.gov (United States)

    Kim, Tae-Hwan; Jung, Sung Hoon; Cho, Kwang-Hyun

    2008-01-01

    Inspired by the recent studies on the analysis of biased random walk behavior of Escherichia coli[Passino, K.M., 2002. Biomimicry of bacterial foraging for distributed optimization and control. IEEE Control Syst. Mag. 22 (3), 52-67; Passino, K.M., 2005. Biomimicry for Optimization, Control and Automation. Springer-Verlag, pp. 768-798; Liu, Y., Passino, K.M., 2002. Biomimicry of social foraging bacteria for distributed optimization: models, principles, and emergent behaviors. J. Optim. Theory Appl. 115 (3), 603-628], we have developed a model describing the motile behavior of E. coli by specifying some simple rules on the chemotaxis. Based on this model, we have analyzed the role of some key parameters involved in the chemotactic behavior to unravel the underlying design principles. By investigating the target tracking capability of E. coli in a maze through computer simulations, we found that E. coli clusters can be controlled as target trackers in a complex micro-scale-environment. In addition, we have explored the dynamical characteristics of this target tracking mechanism through perturbation of parameters under noisy environments. It turns out that the E. coli chemotaxis mechanism might be designed such that it is sensitive enough to efficiently track the target and also robust enough to overcome environmental noises.

  16. Design Principle of A Small Angle Neutron Scattering Spectrometer. Vol. 2

    Energy Technology Data Exchange (ETDEWEB)

    Ashry, A [Dept. of Physics, Faculty of Education, Ain Shams University, Cairo (Egypt)

    1996-03-01

    The design principle of a small angle neutron scattering (SANS) spectrometer is based on producing monochromatic neutron bursts using two phased rotors. The rotors have a number of slots to achieve the highly available intensity of monoenergetic neutrons at the required resolution. The design principle was applied to improve the performance of the pulsed monochromatic double rotor system at ET-RR-1 to operate as SANS spectrometer. It is shown that for rotors having 19 slots each with radius of curvature 96.8 cm, the intensity gain factor is 13. The proposed SANS spectrometer could cover the neutron wavelength range from 2 A{sup {omicron}} up to 6 A{sup {omicron}} through small angles of scattering from 5 x 10{sup -3} rad. to 0.1 rad. i.e, the scattering wavevector transfer between 0.6 A{sup {omicron}-1} and 0.01 A{sup {omicron}-1}. The maximum neutron flux density on the specimen is 5 x 10{sup 5} n cm{sup -2} s{sup -1}. 8 figs.

  17. Design principle for absorption enhancement with nanoparticles in thin-film silicon solar cells

    International Nuclear Information System (INIS)

    Xu, Yuanpei; Xuan, Yimin

    2015-01-01

    The use of nanoparticles in solar cells has created many controversies. In this paper, different mechanisms of nanoparticles with different materials with diameters varying from 50 to 200 nm, surface coverage at 5, 20, and 60 %, and different locations are analyzed systematically for efficient light trapping in a thin-film c-Si solar cell. Mie theory and the finite difference time domain method are used for analysis to give a design principle with nanoparticles for the solar cell application. Metals exhibit plasmonic resonances and angular scattering, while dielectrics show anti-reflection and scattering in the incident direction. A table is given to summarize the advantages and disadvantages in different conditions. The silicon absorption enhancement with nanoparticles on top is mainly in the shorter wavelengths below 700 nm, and both Al and SiO 2 nanoparticles with diameter around 100 nm show the most significant enhancement. The silicon absorption enhancement with embedded nanoparticles takes place in the longer wavelengths over 700 nm, and Ag and SiO 2 nanoparticles with larger diameter around 200 nm perform better. However, the light absorbed by Ag nanoparticles will be converted to heat and will lead to decrease in cell efficiency; hence, the choice of metallic nanoparticles in applications to solar cells should be carefully considered. The design principle proposed in this work gives a guideline by choosing reasonable parameters for the different requirements in the application of thin-film solar cells

  18. Principle of maximum entropy for reliability analysis in the design of machine components

    Science.gov (United States)

    Zhang, Yimin

    2018-03-01

    We studied the reliability of machine components with parameters that follow an arbitrary statistical distribution using the principle of maximum entropy (PME). We used PME to select the statistical distribution that best fits the available information. We also established a probability density function (PDF) and a failure probability model for the parameters of mechanical components using the concept of entropy and the PME. We obtained the first four moments of the state function for reliability analysis and design. Furthermore, we attained an estimate of the PDF with the fewest human bias factors using the PME. This function was used to calculate the reliability of the machine components, including a connecting rod, a vehicle half-shaft, a front axle, a rear axle housing, and a leaf spring, which have parameters that typically follow a non-normal distribution. Simulations were conducted for comparison. This study provides a design methodology for the reliability of mechanical components for practical engineering projects.

  19. Design principles for CANDU control centres in response to evolving utility business needs

    International Nuclear Information System (INIS)

    Davey, E.

    2002-01-01

    Nuclear generation operators are facing a challenging business environment at the beginning of the new millennium. Evolving changes in business context, competitive commercial pressures, and changes in technology have dictated recurring evaluation of operational practices and the adequacy of supporting tools, and the pursuit of opportunities for operational improvement. A key area of utility operations that has been impacted by these changes is the nuclear plant control centre. Changes to workspace layout, equipment provisions, staffing, and work organization are examples of some of the adjustments being introduced to improve operational and safety effectiveness. This paper discusses some of the key factors influencing these changes and identifies additional design principles for CANDU control centres that will enable new control centre designs and retrofits of existing control centres to remain relevant and responsive to utility needs. (author)

  20. Seismic design principles for the German fast breeder reactor SNR 2

    International Nuclear Information System (INIS)

    Busch, K.A.; Peters, K.A.; Rosenhauer, W.

    1987-01-01

    The safety issue of an adequate and optimized external event protection is of course that unnecessary hardware precautions might promote internal disturbances or hamper their control. It has up to now not satisfactorily been realized that the only serious context for seismic impacts on a fast reactor is their attributed potential of overriding core disruptive accident prevention, see e.g. GRS 1982. General and exaggerated antiseismic design features not focussed upon this point may as well turn out to be non-negligible initators in the absence of seismic vibrations. Unexpected snubber difficulties requiring additional reactor scrams and decay heat removal phases may be named as a simple example. The presented seismic design principles reflect the progress made in the concerned fields of analysis and do serve on the other hand as guidelines for research and development efforts under work. (orig./GL)

  1. Principle of human system interface (HSI) design for new reactor console of PUSPATI TRIGA Reactor (RTP)

    International Nuclear Information System (INIS)

    Zareen Khan Abdul Jalil Khan; Ridzuan Abdul Mutalib; Mohd Idris Taib; Mohd Khairulezwan Abdul Manan; Nurfarhana Ayuni Joha; Mohd Sabri Minhat; Izhar Abu Hussin

    2013-01-01

    Full-text: This paper will describe the principle of human system interface design for new reactor console in control room at TRIGA reactor facility. In order to support these human system interface challenges in digital reactor console. Software-based instrumentation and control (I and C) system for new reactor console could lead to new human machine integration. The proposed of Human System Interface (HSI) which included the large display panels which shows reactor status, compact and computer-based workstations for monitoring, control and protection function. The proposed Human System Interface (HIS) has been evaluated using various human factor engineering. It can be concluded that the Human System Interface (HIS) is designed as to address the safety related computer controlled system. (author)

  2. A Program for the Identification of the Enterobacteriaceae for Use in Teaching the Principles of Computer Identification of Bacteria.

    Science.gov (United States)

    Hammonds, S. J.

    1990-01-01

    A technique for the numerical identification of bacteria using normalized likelihoods calculated from a probabilistic database is described, and the principles of the technique are explained. The listing of the computer program is included. Specimen results from the program, and examples of how they should be interpreted, are given. (KR)

  3. Design Principles of Worked Examples: A Review of the Empirical Studies

    Science.gov (United States)

    Shen, Chun-Yi; Tsai, Hui-Chun

    2009-01-01

    Many researchers investigated the efficacy of using worked examples in classroom instruction and provided evidence in the effectiveness of worked example instruction in mathematics, computer programming, physics, and etc. However, there are limited studies in worked example design. The purpose of this study is to generate the instructional design…

  4. Leveraging lean principles in creating a comprehensive quality program: The UCLA health readmission reduction initiative.

    Science.gov (United States)

    Afsar-Manesh, Nasim; Lonowski, Sarah; Namavar, Aram A

    2017-12-01

    UCLA Health embarked to transform care by integrating lean methodology in a key clinical project, Readmission Reduction Initiative (RRI). The first step focused on assembling a leadership team to articulate system-wide priorities for quality improvement. The lean principle of creating a culture of change and accountability was established by: 1) engaging stakeholders, 2) managing the process with performance accountability, and, 3) delivering patient-centered care. The RRI utilized three major lean principles: 1) A3, 2) root cause analyses, 3) value stream mapping. Baseline readmission rate at UCLA from 9/2010-12/2011 illustrated a mean of 12.1%. After the start of the RRI program, for the period of 1/2012-6/2013, the readmission rate decreased to 11.3% (p<0.05). To impact readmissions, solutions must evolve from smaller service- and location-based interventions into strategies with broader approach. As elucidated, a systematic clinical approach grounded in lean methodologies is a viable solution to this complex problem. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Toward a Monte Carlo program for simulating vapor-liquid phase equilibria from first principles

    Energy Technology Data Exchange (ETDEWEB)

    McGrath, M; Siepmann, J I; Kuo, I W; Mundy, C J; Vandevondele, J; Sprik, M; Hutter, J; Mohamed, F; Krack, M; Parrinello, M

    2004-10-20

    Efficient Monte Carlo algorithms are combined with the Quickstep energy routines of CP2K to develop a program that allows for Monte Carlo simulations in the canonical, isobaric-isothermal, and Gibbs ensembles using a first principles description of the physical system. Configurational-bias Monte Carlo techniques and pre-biasing using an inexpensive approximate potential are employed to increase the sampling efficiency and to reduce the frequency of expensive ab initio energy evaluations. The new Monte Carlo program has been validated through extensive comparison with molecular dynamics simulations using the programs CPMD and CP2K. Preliminary results for the vapor-liquid coexistence properties (T = 473 K) of water using the Becke-Lee-Yang-Parr exchange and correlation energy functionals, a triple-zeta valence basis set augmented with two sets of d-type or p-type polarization functions, and Goedecker-Teter-Hutter pseudopotentials are presented. The preliminary results indicate that this description of water leads to an underestimation of the saturated liquid density and heat of vaporization and, correspondingly, an overestimation of the saturated vapor pressure.

  6. Proactive Management of Materials Degradation - A Review of Principles and Programs

    Energy Technology Data Exchange (ETDEWEB)

    Bond, Leonard J.; Doctor, Steven R.; Taylor, Theodore T.

    2008-08-28

    The U.S. Nuclear Regulatory Commission (NRC) has undertaken a program to lay the technical foundation for defining proactive actions so that future degradation of materials in light water reactors (LWRs) is limited and, thereby, does not diminish either the integrity of important LWR components or the safety of operating plants. This technical letter report was prepared by staff at Pacific Northwest National Laboratory in support of the NRC Proactive Management of Materials Degradation (PMMD) program and relies heavily on work that was completed by Dr. Joseph Muscara and documented in NUREG/CR-6923. This report concisely explains the basic principles of PMMD and its relationship to prognostics, provides a review of programs related to PMMD being conducted worldwide, and provides an assessment of the technical gaps in PMMD and prognostics that need to be addressed. This technical letter report is timely because the majority of the U.S. reactor fleet is applying for license renewal, and many plants are also applying for increases in power rating. Both of these changes could increase the likelihood of materials degradation and underline, therefore, the interest in proactive management in the future.

  7. Management of educational programs on the base of standardization principles application

    Directory of Open Access Journals (Sweden)

    O. S. Nikulcheva

    2016-01-01

    Full Text Available Contemporary higher education is characterized by the development of innovative teaching technologies. This process leads to the necessity of their systematization and classification. The transformation carried out at the high school meets the modern trends of the world scientific and technical progress development. Such innovative method as the audiovisual aids in teaching completes traditional educational process improving its effectiveness. Method of training projects is aimed at the development of students individual and group autonomy, it makes the students apply synthesis and analysis technique, and determine the methods and means of obtaining results. It is a multifunctional method of learning, teaching and training. Educational programs management in higher educational institutions is possible when applying the principle of consistency and optimizing the innovative teaching methods integration in educational process. When adopting modern teaching methods it is necessary to solve the problem of material and technical support of educational process. It is of great importance to develop standards for material and technical support of innovative educational programs in order to create a single harmonized educational space. The progress of information technologies will allow us to use the advantages of online learning, which will be based on the online lectures prepared by the leading Universities of the country. Higher educational institutions in such conditions will play a role of supporting and consulting centers. This form is more democratic, it allows us to vary the time of training however its application requires methodical, organizational and systemic preparation. Adopting innovative methods and technologies it should be followed the principle of total quality management involving the teaching staff in the process of the united team formation.

  8. Principles of Emergency Department facility design for optimal management of mass-casualty incidents.

    Science.gov (United States)

    Halpern, Pinchas; Goldberg, Scott A; Keng, Jimmy G; Koenig, Kristi L

    2012-04-01

    The Emergency Department (ED) is the triage, stabilization and disposition unit of the hospital during a mass-casualty incident (MCI). With most EDs already functioning at or over capacity, efficient management of an MCI requires optimization of all ED components. While the operational aspects of MCI management have been well described, the architectural/structural principles have not. Further, there are limited reports of the testing of ED design components in actual MCI events. The objective of this study is to outline the important infrastructural design components for optimization of ED response to an MCI, as developed, implemented, and repeatedly tested in one urban medical center. In the authors' experience, the most important aspects of ED design for MCI have included external infrastructure and promoting rapid lockdown of the facility for security purposes; an ambulance bay permitting efficient vehicle flow and casualty discharge; strategic placement of the triage location; patient tracking techniques; planning adequate surge capacity for both patients and staff; sufficient command, control, communications, computers, and information; well-positioned and functional decontamination facilities; adequate, well-located and easily distributed medical supplies; and appropriately built and functioning essential services. Designing the ED to cope well with a large casualty surge during a disaster is not easy, and it may not be feasible for all EDs to implement all the necessary components. However, many of the components of an appropriate infrastructural design add minimal cost to the normal expenditures of building an ED. This study highlights the role of design and infrastructure in MCI preparedness in order to assist planners in improving their ED capabilities. Structural optimization calls for a paradigm shift in the concept of structural and operational ED design, but may be necessary in order to maximize surge capacity, department resilience, and patient and

  9. Designing an Interactive OER Course Development at Athabasca University Based on ODL Principles

    Directory of Open Access Journals (Sweden)

    Hongxin Yan

    2013-11-01

    Full Text Available Failure rates in first year calculus courses are high in most post-secondary institutions across North America and other parts of the world. This Inukshuk-funded open education project involved the development of five stand-alone pre-calculus learning modules. The design and revision phases of this project occurred between the fall of 2007 and late spring of 2009. These modules were designed to support learners enrolled in first year calculus by providing just-in-time instruction in five areas: algebraic operations, factorization, polynomials and rational expressions, radical expressions, linear and quadratic equations. One of the major challenges of the project was developing dynamic activities that could support the display of a variety of mathematical formulas. To this end an open source Flash-based authoring tool was developed called the Athabasca University Tutor Authoring Tool (AUTAT. This paper explores the design and development of the AUTAT based on the needs assessment and design principles discussed.

  10. Explaining success and failure in the commons: the configural nature of Ostrom's institutional design principles

    Directory of Open Access Journals (Sweden)

    Jacopo Alessandro Baggio

    2016-09-01

    Full Text Available Governing common pool resources (CPR in the face of disturbances such as globalization and climate change is challenging. The outcome of any CPR governance regime is the influenced by local combinations of social, institutional, and biophysical factors, as well as cross-scale interdependencies. In this study, we take a step towards understanding multiple-causation of CPR outcomes by analyzing 1 the co-occurrence of Destign Principles (DP by activity (irrigation, fishery and forestry, and 2 the combination(s of DPs leading to social and ecological success. We analyzed 69 cases pertaining to three different activities: irrigation, fishery, and forestry. We find that the importance of the design principles is dependent upon the natural and hard human made infrastructure (i.e. canals, equipment, vessels etc.. For example, clearly defined social bounduaries are important when the natural infrastructure is highly mobile (i.e. tuna fish, while monitoring is more important when the natural infrastructure is more static (i.e. forests or water contained within an irrigation system. However, we also find that congruence between local conditions and rules and proportionality between investment and extraction are key for CPR success independent from the natural and human hard made infrastructure. We further provide new visualization techniques for co-occurrence patterns and add to qualitative comparative analysis by introducing a reliability metric to deal with a large meta-analysis dataset on secondary data where information is missing or uncertain.

  11. Controller design approach based on linear programming.

    Science.gov (United States)

    Tanaka, Ryo; Shibasaki, Hiroki; Ogawa, Hiromitsu; Murakami, Takahiro; Ishida, Yoshihisa

    2013-11-01

    This study explains and demonstrates the design method for a control system with a load disturbance observer. Observer gains are determined by linear programming (LP) in terms of the Routh-Hurwitz stability criterion and the final-value theorem. In addition, the control model has a feedback structure, and feedback gains are determined to be the linear quadratic regulator. The simulation results confirmed that compared with the conventional method, the output estimated by our proposed method converges to a reference input faster when a load disturbance is added to a control system. In addition, we also confirmed the effectiveness of the proposed method by performing an experiment with a DC motor. © 2013 ISA. Published by ISA. All rights reserved.

  12. Ab initio identified design principles of solid-solution strengthening in Al

    International Nuclear Information System (INIS)

    Ma Duancheng; Friák, Martin; Pezold, Johann von; Raabe, Dierk; Neugebauer, Jörg

    2013-01-01

    Solid-solution strengthening in six Al–X binary systems is investigated using first-principle methods. The volumetric mismatch parameter and the solubility enthalpy per solute were calculated. We derive three rules for designing solid-solution strengthened alloys: (i) the solubility enthalpy per solute is related to the volumetric mismatch by a power law; (ii) for each annealing temperature, there exists an optimal solute–volume mismatch to achieve maximum strength; and (iii) the strengthening potential of high volumetric mismatch solutes is severely limited by their low solubility. Our results thus show that the thermodynamic properties of the system (here Al–X alloys) set clear upper bounds to the achievable strengthening effects owing to the reduced solubility with increasing volume mismatch. (paper)

  13. Novel Geometrical Concept of a High Performance Brain PET Scanner Principle, Design and Performance Estimates

    CERN Document Server

    Séguinot, Jacques; Chesi, Enrico Guido; Joram, C; Mathot, S; Weilhammer, P; Chamizo-Llatas, M; Correia, J G; Ribeiro da Silva, M; Garibaldi, F; De Leo, R; Nappi, E; Corsi, F; Dragone, A; Schoenahl, F; Zaidi, H

    2006-01-01

    We present the principle, a possible implementation and performance estimates of a novel geometrical concept for a high resolution positron emission tomograph. The concept, which can for example be implemented in a brain PET device, promisses to lead to an essentially parallax free 3D image reconstruction with excellent spatial resolution and constrast, uniform over the complete field of view. The key components are matrices of long axially oriented scintillator crystals which are read out at both extremities by segmented Hybrid Photon Detectors. We discuss the relevant design considerations for a 3D axial PET camera module, motivate parameter and material choices, and estimate its performance in terms of spatial and energy resolution. We support these estimates by Monte Carlo simulations and in some cases by first experimental results. From the performance of a camera module, we extrapolate to the reconstruction resolution of a 3D axial PET scanner in a semi-analytical way and compare it to an existing state...

  14. Design of a digital PAD based on I/Q demodulation principle

    International Nuclear Information System (INIS)

    Geng Zheqiao; Cui Yanyan; Hou Mi; Pei Guoxi

    2005-01-01

    Conventional analog I/Q demodulator suffers from phase and amplitude imbalance and DC offset, which cause big error into the measurement. A digital PAD is designed. Based on I/Q demodulation principle, using digital algorithms, such as digital filter and Hilbert transform, the conventional measurement error can basically be removed. Measuremental results show that the digital PAD has a maximum phase error of ±0.5 degree and a resolution of 0.2 degree. Its temperature coefficient is -0.1 degree/degree C. Its dynamic ranges for phase-measurement and amplitude-measurement are -1825 dBm and -2020 dBm, respectively. The digital PAD can meet the need of the BEPC II phasing system. (authors)

  15. Design principle of TVO's final repository and preliminary adaptation to site specific conditions

    International Nuclear Information System (INIS)

    Salo, J-P.; Reikkola, R.

    1995-01-01

    Teollisuuden Voima Oy (TVO) is responsible for the management of spent fuel produced by the Olkiluoto power plant. TVO's current programme of spent fuel management is based on the guidelines and time schedule set by the Finnish Government. TVO has studied a final disposal concept in which the spent fuel bundles are encapsulated in copper canisters and emplaced in Finnish bedrock. According to the plan the final repository for spent fuel will be in operation by 2020. TVO's updated technical plans for the disposal of spent fuel together with a performance analysis (TVO-92) were submitted to the authorities in 1992. The paper describes the design principle of TVO's final repository and preliminary adaptation of the repository to site specific conditions. (author). 10 refs., 5 figs

  16. Principles of designing mobile robots for nuclear applications: Some Soviet development projects

    International Nuclear Information System (INIS)

    Adamov, E.O.; Ivanov, V.G.; Meieran, H.B.

    1990-01-01

    The I.V. Kurchatov Institute of Atomic Energy and the Research and Design Institute of Power Engineering, both designers of nuclear power plant systems and located in Moscow, USSR, have collectively recognized the positive merits of utilizing mobile robots in the nuclear industry. They have given authority to their subsidiary agency CENOTECH to mount an active campaign to program the development of new generations of mobile robots that will support routine and emergency situation operations in the nuclear industry. CENOTECH's rationale for design and performance requirements of mobile robot units to be utilized in the nuclear industry is presented in this paper. A description of design, performance requirements, and operational characteristics of four mobile robots that have been developed at CENOTECH within the past 3 yr is also presented: the 2-tracked KURSOR; the 4 hybrid-wheeled TELER; the 12-wheeled BUGGY with articulated platforms; and the 2-tracked SADKO

  17. Does Implementation Follow Design? A Case Study of a Workplace Health Promotion Program Using the 4-S Program Design and the PIPE Impact Metric Evaluation Models.

    Science.gov (United States)

    Äikäs, Antti Hermanni; Pronk, Nicolaas P; Hirvensalo, Mirja Hannele; Absetz, Pilvikki

    2017-08-01

    The aim of this study was to describe the content of a multiyear market-based workplace health promotion (WHP) program and to evaluate design and implementation processes in a real-world setting. Data was collected from the databases of the employer and the service provider. It was classified using the 4-S (Size, Scope, Scalability, and Sustainability) and PIPE Impact Metric (Penetration, Implementation) models. Data analysis utilized both qualitative and quantitative methods. Program design covered well the evidence-informed best practices except for clear path toward sustainability, cooperation with occupational health care, and support from middle-management supervisors. The penetration rate among participants was high (99%) and majority (81%) of services were implemented as designed. Study findings indicate that WHP market would benefit the use of evidence-based design principles and tendentious decisions to anticipate a long-term implementation process already during the planning phase.

  18. Applications of Context-Aware Computing in Hospital Work - Examples and Design Principles

    DEFF Research Database (Denmark)

    Bardram, Jacob Eyvind

    2004-01-01

    Context-awareness is a key concept in ubiquitous computing, which sometimes seems to be a technology looking for a purpose. In this paper we report on the application of context-aware computing for medical work in hospitals, which has appeared to be a strong case for applying context-aware comput...... of designing, developing, and evaluating context-aware clinical applications, the paper outlines some key design principles for a context-awareness framework, supporting the development and deployment of context-aware clinical computer applications.......Context-awareness is a key concept in ubiquitous computing, which sometimes seems to be a technology looking for a purpose. In this paper we report on the application of context-aware computing for medical work in hospitals, which has appeared to be a strong case for applying context......-aware computing. We present the design of a context-aware pill container and a context-aware hospital bed, both of which reacts and adapts according to what is happening in their context. The applications have been evaluated in a number of workshop with clinicians and patients. Based on this empirical work...

  19. Extending the generality of leaf economic design principles in the cycads, an ancient lineage.

    Science.gov (United States)

    Zhang, Yong-Jiang; Cao, Kun-Fang; Sack, Lawren; Li, Nan; Wei, Xue-Mei; Goldstein, Guillermo

    2015-04-01

    Cycads are the most ancient lineage of living seed plants, but the design of their leaves has received little study. We tested whether cycad leaves are governed by the same fundamental design principles previously established for ferns, conifers and angiosperms, and characterized the uniqueness of this relict lineage in foliar trait relationships. Leaf structure, photosynthesis, hydraulics and nutrient composition were studied in 33 cycad species from nine genera and three families growing in two botanical gardens. Cycads varied greatly in leaf structure and physiology. Similarly to other lineages, light-saturated photosynthetic rate per mass (Am ) was related negatively to leaf mass per area and positively to foliar concentrations of chlorophyll, nitrogen (N), phosphorus and iron, but unlike angiosperms, leaf photosynthetic rate was not associated with leaf hydraulic conductance. Cycads had lower photosynthetic N use efficiency and higher photosynthetic performance relative to hydraulic capacity compared with other lineages. These findings extend the relationships shown for foliar traits in angiosperms to the cycads. This functional convergence supports the modern synthetic understanding of leaf design, with common constraints operating across lineages, even as they highlight exceptional aspects of the biology of this key relict lineage. © 2015 The Authors. New Phytologist © 2015 New Phytologist Trust.

  20. [Principles and methodology for ecological rehabilitation and security pattern design in key project construction].

    Science.gov (United States)

    Chen, Li-Ding; Lu, Yi-He; Tian, Hui-Ying; Shi, Qian

    2007-03-01

    Global ecological security becomes increasingly important with the intensive human activities. The function of ecological security is influenced by human activities, and in return, the efficiency of human activities will also be affected by the patterns of regional ecological security. Since the 1990s, China has initiated the construction of key projects "Yangtze Three Gorges Dam", "Qinghai-Tibet Railway", "West-to-East Gas Pipeline", "West-to-East Electricity Transmission" and "South-to-North Water Transfer" , etc. The interaction between these projects and regional ecological security has particularly attracted the attention of Chinese government. It is not only important for the regional environmental protection, but also of significance for the smoothly implementation of various projects aimed to develop an ecological rehabilitation system and to design a regional ecological security pattern. This paper made a systematic analysis on the types and characteristics of key project construction and their effects on the environment, and on the basis of this, brought forward the basic principles and methodology for ecological rehabilitation and security pattern design in this construction. It was considered that the following issues should be addressed in the implementation of a key project: 1) analysis and evaluation of current regional ecological environment, 2) evaluation of anthropogenic disturbances and their ecological risk, 3) regional ecological rehabilitation and security pattern design, 4) scenario analysis of environmental benefits of regional ecological security pattern, 5) re-optimization of regional ecological system framework, and 6) establishment of regional ecosystem management plan.

  1. HIGH QUALITY ENVIRONMENTAL PRINCIPLES APPLIED TO THE ARCHITECTONIC DESIGN SELECTION PROCEDURE: THE NUTRE LAB CASE

    Directory of Open Access Journals (Sweden)

    Claudia Barroso Krause

    2012-06-01

    Full Text Available The need to produce more sustainable buildings has been influencing the design decisions all over the world. That’s why it is imperative, in Brazil, the development of strategies and method to aid the decision making during the design process, focused on high quality environmental. This paper presents a decision support tool based on the principles of sustainable construction developed by the Project, Architecture and Sustainability Research Group (GPAS of Federal University of Rio de Janeiro – Brazil. The methodology has been developed for the selection of a preliminary design of a laboratory to be built at Rio Technology Park at the University campus. The support provided by GPAS occurred in three stages: the elaboration of the Reference Guide for the competitors, the development of a methodology to evaluate the proposed solutions (based on environmental performance criteria and the assistance of the members of jury in the trial phase. The theoretical framework was based upon the concepts of the bioclimatic architecture, the procedures specified by the certification HQE® (Haute Qualité Environnementale and the method suggested by the ADDENDA® architecture office. The success of this experience points out the possibility to future application in similar cases.

  2. Design principles of nuclear receptor signaling: how complex networking improves signal transduction

    Science.gov (United States)

    Kolodkin, Alexey N; Bruggeman, Frank J; Plant, Nick; Moné, Martijn J; Bakker, Barbara M; Campbell, Moray J; van Leeuwen, Johannes P T M; Carlberg, Carsten; Snoep, Jacky L; Westerhoff, Hans V

    2010-01-01

    The topology of nuclear receptor (NR) signaling is captured in a systems biological graphical notation. This enables us to identify a number of ‘design' aspects of the topology of these networks that might appear unnecessarily complex or even functionally paradoxical. In realistic kinetic models of increasing complexity, calculations show how these features correspond to potentially important design principles, e.g.: (i) cytosolic ‘nuclear' receptor may shuttle signal molecules to the nucleus, (ii) the active export of NRs may ensure that there is sufficient receptor protein to capture ligand at the cytoplasmic membrane, (iii) a three conveyor belts design dissipating GTP-free energy, greatly aids response, (iv) the active export of importins may prevent sequestration of NRs by importins in the nucleus and (v) the unspecific nature of the nuclear pore may ensure signal-flux robustness. In addition, the models developed are suitable for implementation in specific cases of NR-mediated signaling, to predict individual receptor functions and differential sensitivity toward physiological and pharmacological ligands. PMID:21179018

  3. Design principles of natural light-harvesting as revealed by single molecule spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Krüger, T.P.J., E-mail: tjaart.kruger@up.ac.za [Department of Physics, University of Pretoria, Private bag X20, Hatfield 0028 (South Africa); Grondelle, R. van [Department of Physics and Astronomy, VU University Amsterdam, De Boelelaan 1081, 1081 HV Amsterdam (Netherlands)

    2016-01-01

    Biology offers a boundless source of adaptation, innovation, and inspiration. A wide range of photosynthetic organisms exist that are capable of harvesting solar light in an exceptionally efficient way, using abundant and low-cost materials. These natural light-harvesting complexes consist of proteins that strongly bind a high density of chromophores to capture solar photons and rapidly transfer the excitation energy to the photochemical reaction centre. The amount of harvested light is also delicately tuned to the level of solar radiation to maintain a constant energy throughput at the reaction centre and avoid the accumulation of the products of charge separation. In this Review, recent developments in the understanding of light-harvesting by plants will be discussed, based on results obtained from single molecule spectroscopy studies. Three design principles of the main light-harvesting antenna of plants will be highlighted: (a) fine, photoactive control over the intrinsic protein disorder to efficiently use intrinsically available thermal energy dissipation mechanisms; (b) the design of the protein microenvironment of a low-energy chromophore dimer to control the amount of shade absorption; (c) the design of the exciton manifold to ensure efficient funneling of the harvested light to the terminal emitter cluster.

  4. Striking a Balance between Program Requirements and GT Principles: Writing a compromised GT proposal

    Directory of Open Access Journals (Sweden)

    Sherry L. Xie, Ph.D. Candidate

    2009-06-01

    Full Text Available Glaser’s term “compromised GT proposal” (2001, p.114 refers to the type of Grounded Theory (GT proposal that is written in order to conform to the requirements of a standardized qualitative research proposal. A GT proposal needs only to supply information on the area of interest, the data source and a statement of method to the effect that the researcher begin to collect, code and analyse the data and let the theory emerge. Thus, the proposal may only occupy “a page or two” (Glaser, 2001, p. 111. Whilst being consistent with the methodology, a GT proposal sometimes has to give way to the format specified by a PhD program or committee even though the format was not defined for a GT proposal and in some areas, conflicts with GT principles; for example, the format may require a literature review. This short paper reports on my experience of writing a compromised GT proposal as a first-time GT researcher. It describes how both Glaser’s advice on writing compromised GT research proposals and the characteristics of the substantive area of the proposed research were used to satisfy program requirements while still maintaining GT fundamentals.

  5. NASA universities advanced space design program, focus on nuclear engineering

    International Nuclear Information System (INIS)

    Lyon, W.F. III; George, J.A.; Alred, J.W.; Peddicord, K.L.

    1987-01-01

    In January 1985, the National Aeronautics and Space Administration (NASA), in affiliation with the Universities Space Research Association (USRA), inaugurated the NASA Universities Advanced Space Design Program. The purpose of the program was to encourage participating universities to utilize design projects for the senior and graduate level design courses that would focus on topics relevant to the nation's space program. The activities and projects being carried out under the NASA Universities Advanced Space Design Program are excellent experiences for the participants. This program is a well-conceived, well-planned effort to achieve the maximum benefit out of not only the university design experience but also of the subsequent summer programs. The students in the university design classes have the opportunity to investigate dramatic and new concepts, which at the same time have a place in a program of national importance. This program could serve as a very useful model for the development of university interaction with other federal agencies

  6. Urban Space Innovation - “10+” Principles through Designing the New Image of the Existing Shopping Mall in Csepel, Hungary

    Science.gov (United States)

    Gyergyak, Janos

    2017-10-01

    The first part of the paper is about to introduce the principles of “placemaking” as an innovation and important tool of the cities in the 21st century. The process helps designers to transform the spaces of “nobody” to a community-based space for supporting the connection among humans. The second part of the paper shows the process of the used principles by the author for designing the new image of the existing shopping mall in Csepel, Hungary. This work was selected as one of the best design ideas for renewing the existing underutilized space.

  7. Integrating computer programs for engineering analysis and design

    Science.gov (United States)

    Wilhite, A. W.; Crisp, V. K.; Johnson, S. C.

    1983-01-01

    The design of a third-generation system for integrating computer programs for engineering and design has been developed for the Aerospace Vehicle Interactive Design (AVID) system. This system consists of an engineering data management system, program interface software, a user interface, and a geometry system. A relational information system (ARIS) was developed specifically for the computer-aided engineering system. It is used for a repository of design data that are communicated between analysis programs, for a dictionary that describes these design data, for a directory that describes the analysis programs, and for other system functions. A method is described for interfacing independent analysis programs into a loosely-coupled design system. This method emphasizes an interactive extension of analysis techniques and manipulation of design data. Also, integrity mechanisms exist to maintain database correctness for multidisciplinary design tasks by an individual or a team of specialists. Finally, a prototype user interface program has been developed to aid in system utilization.

  8. Climate-responsive design: A framework for an energy concept design-decision support tool for architects using principles of climate-responsive design

    Directory of Open Access Journals (Sweden)

    Remco Looman

    2017-01-01

    Full Text Available In climate-responsive design the building becomes an intermediary in its own energy housekeeping, forming a link between the harvest of climate resources and low energy provision of comfort. Essential here is the employment of climate-responsive building elements, defined as structural and architectural elements in which the energy infrastructure is far-reaching integrated. This thesis presents the results of research conducted on what knowledge is needed in the early stages of the design process and how to transfer and transform that knowledge to the field of the architect in order for them to successfully implement the principles of climate-responsive design. The derived content, form and functional requirements provide the framework for a design decision support tool. These requirements were incorporated into a concept tool that has been presented to architects in the field, in order to gain their feedback. Climate-responsive design makes the complex task of designing even more complex. Architects are helped when sufficient information on the basics of climate-responsive design and its implications are provided as informative support during decision making in the early design stages of analysis and energy concept development. This informative support on climate-responsive design should address to different design styles in order to be useful to any type of architects. What is defined as comfortable has far-reaching implications for the way buildings are designed and how they operate. This in turn gives an indication of the energy used for maintaining a comfortable indoor environment. Comfort is not a strict situation, but subjective. Diversity is appreciated and comfort is improved when users have the ability to exert influence on their environment. Historically, the provision of comfort has led to the adoption of mechanical climate control systems that operate in many cases indifferent from the building space and mass and its environment

  9. Utilizing Design Information in Aspect-Oriented Programming

    OpenAIRE

    Nagy, I.; Bergmans, Lodewijk; Havinga, W.K.; Aksit, Mehmet; Hirschfeld, Robert; Kowalczyk, Ryszard; Polze, Andreas; Weske, Mathias

    2005-01-01

    Traditionally in aspect-oriented languages, pointcut designators select joinpoints of a program based on lexical information such as explicit names of program elements. However, this reduces the adaptability of software, since it involves too much information that is hard-coded, and often implementationspecific. We claim that this problem can be reduced by referring to program units through their design intentions. Design intention is represented by annotated design information, which describ...

  10. Water, Resilience and the Law: From General Concepts and Governance Design Principles to Actionable Mechanisms

    Science.gov (United States)

    Hill Clarvis, M.; Allan, A.; Hannah, D. M.

    2013-12-01

    least data infrastructure. The article aims to contribute to both theory and practice, enabling policy makers to translate resilience based terminology and adaptive governance principles into clear instructions for incorporating uncertainty into legislation and policy design.

  11. A mechanical design principle for tissue structure and function in the airway tree.

    Science.gov (United States)

    LaPrad, Adam S; Lutchen, Kenneth R; Suki, Béla

    2013-01-01

    With every breath, the dynamically changing mechanical pressures must work in unison with the cells and soft tissue structures of the lung to permit air to efficiently traverse the airway tree and undergo gas exchange in the alveoli. The influence of mechanics on cell and tissue function is becoming apparent, raising the question: how does the airway tree co-exist within its mechanical environment to maintain normal cell function throughout its branching structure of diminishing dimensions? We introduce a new mechanical design principle for the conducting airway tree in which mechanotransduction at the level of cells is driven to orchestrate airway wall structural changes that can best maintain a preferred mechanical microenvironment. To support this principle, we report in vitro radius-transmural pressure relations for a range of airway radii obtained from healthy bovine lungs and model the data using a strain energy function together with a thick-walled cylinder description. From this framework, we estimate circumferential stresses and incremental Young's moduli throughout the airway tree. Our results indicate that the conducting airways consistently operate within a preferred mechanical homeostatic state, termed mechanical homeostasis, that is characterized by a narrow range of circumferential stresses and Young's moduli. This mechanical homeostatic state is maintained for all airways throughout the tree via airway wall dimensional and mechanical relationships. As a consequence, cells within the airway walls throughout the airway tree experience similar oscillatory strains during breathing that are much smaller than previously thought. Finally, we discuss the potential implications of how the maintenance of mechanical homeostasis, while facilitating healthy tissue-level alterations necessary for maturation, may lead to airway wall structural changes capable of chronic asthma.

  12. A mechanical design principle for tissue structure and function in the airway tree.

    Directory of Open Access Journals (Sweden)

    Adam S LaPrad

    Full Text Available With every breath, the dynamically changing mechanical pressures must work in unison with the cells and soft tissue structures of the lung to permit air to efficiently traverse the airway tree and undergo gas exchange in the alveoli. The influence of mechanics on cell and tissue function is becoming apparent, raising the question: how does the airway tree co-exist within its mechanical environment to maintain normal cell function throughout its branching structure of diminishing dimensions? We introduce a new mechanical design principle for the conducting airway tree in which mechanotransduction at the level of cells is driven to orchestrate airway wall structural changes that can best maintain a preferred mechanical microenvironment. To support this principle, we report in vitro radius-transmural pressure relations for a range of airway radii obtained from healthy bovine lungs and model the data using a strain energy function together with a thick-walled cylinder description. From this framework, we estimate circumferential stresses and incremental Young's moduli throughout the airway tree. Our results indicate that the conducting airways consistently operate within a preferred mechanical homeostatic state, termed mechanical homeostasis, that is characterized by a narrow range of circumferential stresses and Young's moduli. This mechanical homeostatic state is maintained for all airways throughout the tree via airway wall dimensional and mechanical relationships. As a consequence, cells within the airway walls throughout the airway tree experience similar oscillatory strains during breathing that are much smaller than previously thought. Finally, we discuss the potential implications of how the maintenance of mechanical homeostasis, while facilitating healthy tissue-level alterations necessary for maturation, may lead to airway wall structural changes capable of chronic asthma.

  13. The Principle of the Micro-Electronic Neural Bridge and a Prototype System Design.

    Science.gov (United States)

    Huang, Zong-Hao; Wang, Zhi-Gong; Lu, Xiao-Ying; Li, Wen-Yuan; Zhou, Yu-Xuan; Shen, Xiao-Yan; Zhao, Xin-Tai

    2016-01-01

    The micro-electronic neural bridge (MENB) aims to rebuild lost motor function of paralyzed humans by routing movement-related signals from the brain, around the damage part in the spinal cord, to the external effectors. This study focused on the prototype system design of the MENB, including the principle of the MENB, the neural signal detecting circuit and the functional electrical stimulation (FES) circuit design, and the spike detecting and sorting algorithm. In this study, we developed a novel improved amplitude threshold spike detecting method based on variable forward difference threshold for both training and bridging phase. The discrete wavelet transform (DWT), a new level feature coefficient selection method based on Lilliefors test, and the k-means clustering method based on Mahalanobis distance were used for spike sorting. A real-time online spike detecting and sorting algorithm based on DWT and Euclidean distance was also implemented for the bridging phase. Tested by the data sets available at Caltech, in the training phase, the average sensitivity, specificity, and clustering accuracies are 99.43%, 97.83%, and 95.45%, respectively. Validated by the three-fold cross-validation method, the average sensitivity, specificity, and classification accuracy are 99.43%, 97.70%, and 96.46%, respectively.

  14. [Hygienic principles of the design of the space and architectural environment of kindergartens].

    Science.gov (United States)

    Stepanova, M I; Kuchma, V R

    In the article there are considered current requirements for the design of the architectural environment of preschool institutions. These requirements provide conditions ofpreservation and promotion of health ofpreschool children. Among them are: the association of rooms according to a functional purpose; division of children collectives according to the age; rational placement of main rooms for the prevention ofpenetration of noise and pollution; ensuring convenientfunctional connections between different premises and group rooms and the parcel ofpreschool institutions; optimal solution of the light mode; rational air and thermal mode. There are made proposals for the expansion of the list of hygienic principles of the design of buildings of kindergartens: provision of conditions for realization of physical activity of children, the safe use of electronic educational equipment, and the creation of the barrier-free environment. There was established the insufficiency of areas of group rooms for the realization of voluntary motor activity of children in modern kindergartens and the need of the revision of the standard of the area of the group room per one child.

  15. Designing the Health-related Internet of Things: Ethical Principles and Guidelines

    Directory of Open Access Journals (Sweden)

    Brent Mittelstadt

    2017-07-01

    Full Text Available The conjunction of wireless computing, ubiquitous Internet access, and the miniaturisation of sensors have opened the door for technological applications that can monitor health and well-being outside of formal healthcare systems. The health-related Internet of Things (H-IoT increasingly plays a key role in health management by providing real-time tele-monitoring of patients, testing of treatments, actuation of medical devices, and fitness and well-being monitoring. Given its numerous applications and proposed benefits, adoption by medical and social care institutions and consumers may be rapid. However, a host of ethical concerns are also raised that must be addressed. The inherent sensitivity of health-related data being generated and latent risks of Internet-enabled devices pose serious challenges. Users, already in a vulnerable position as patients, face a seemingly impossible task to retain control over their data due to the scale, scope and complexity of systems that create, aggregate, and analyse personal health data. In response, the H-IoT must be designed to be technologically robust and scientifically reliable, while also remaining ethically responsible, trustworthy, and respectful of user rights and interests. To assist developers of the H-IoT, this paper describes nine principles and nine guidelines for ethical design of H-IoT devices and data protocols.

  16. Ultra-high resolution flat-panel volume CT: fundamental principles, design architecture, and system characterization

    International Nuclear Information System (INIS)

    Gupta, Rajiv; Brady, Tom; Grasruck, Michael; Suess, Christoph; Schmidt, Bernhard; Stierstorfer, Karl; Popescu, Stefan; Flohr, Thomas; Bartling, Soenke H.

    2006-01-01

    Digital flat-panel-based volume CT (VCT) represents a unique design capable of ultra-high spatial resolution, direct volumetric imaging, and dynamic CT scanning. This innovation, when fully developed, has the promise of opening a unique window on human anatomy and physiology. For example, the volumetric coverage offered by this technology enables us to observe the perfusion of an entire organ, such as the brain, liver, or kidney, tomographically (e.g., after a transplant or ischemic event). By virtue of its higher resolution, one can directly visualize the trabecular structure of bone. This paper describes the basic design architecture of VCT. Three key technical challenges, viz., scatter correction, dynamic range extension, and temporal resolution improvement, must be addressed for successful implementation of a VCT scanner. How these issues are solved in a VCT prototype and the modifications necessary to enable ultra-high resolution volumetric scanning are described. The fundamental principles of scatter correction and dose reduction are illustrated with the help of an actual prototype. The image quality metrics of this prototype are characterized and compared with a multi-detector CT (MDCT). (orig.)

  17. Design principles and field performance of a solar spectral irradiance meter

    Energy Technology Data Exchange (ETDEWEB)

    Tatsiankou, V.; Hinzer, K.; Haysom, J.; Schriemer, H.; Emery, K.; Beal, R.

    2016-08-01

    A solar spectral irradiance meter (SSIM), designed for measuring the direct normal irradiance (DNI) in six wavelength bands, has been combined with models to determine key atmospheric transmittances and the resulting spectral irradiance distribution of DNI under all sky conditions. The design principles of the SSIM, implementation of a parameterized transmittance model, and field performance comparisons of modeled solar spectra with reference radiometer measurements are presented. Two SSIMs were tested and calibrated at the National Renewable Energy Laboratory (NREL) against four spectroradiometers and an absolute cavity radiometer. The SSIMs' DNI was on average within 1% of the DNI values reported by one of NREL's primary absolute cavity radiometers. An additional SSIM was installed at the SUNLAB Outdoor Test Facility in September 2014, with ongoing collection of environmental and spectral data. The SSIM's performance in Ottawa was compared against a commercial pyrheliometer and a spectroradiometer over an eight month study. The difference in integrated daily spectral irradiance between the SSIM and the ASD spectroradiometer was found to be less than 1%. The cumulative energy density collected by the SSIM over this duration agreed with that measured by an Eppley model NIP pyrheliometer to within 0.5%. No degradation was observed.

  18. Ultra-high resolution flat-panel volume CT: fundamental principles, design architecture, and system characterization

    Energy Technology Data Exchange (ETDEWEB)

    Gupta, Rajiv; Brady, Tom [Massachusetts General Hospital, Department of Radiology, Founders House, FND-2-216, Boston, MA (United States); Grasruck, Michael; Suess, Christoph; Schmidt, Bernhard; Stierstorfer, Karl; Popescu, Stefan; Flohr, Thomas [Siemens Medical Solutions, Forchheim (Germany); Bartling, Soenke H. [Hannover Medical School, Department of Neuroradiology, Hannover (Germany)

    2006-06-15

    Digital flat-panel-based volume CT (VCT) represents a unique design capable of ultra-high spatial resolution, direct volumetric imaging, and dynamic CT scanning. This innovation, when fully developed, has the promise of opening a unique window on human anatomy and physiology. For example, the volumetric coverage offered by this technology enables us to observe the perfusion of an entire organ, such as the brain, liver, or kidney, tomographically (e.g., after a transplant or ischemic event). By virtue of its higher resolution, one can directly visualize the trabecular structure of bone. This paper describes the basic design architecture of VCT. Three key technical challenges, viz., scatter correction, dynamic range extension, and temporal resolution improvement, must be addressed for successful implementation of a VCT scanner. How these issues are solved in a VCT prototype and the modifications necessary to enable ultra-high resolution volumetric scanning are described. The fundamental principles of scatter correction and dose reduction are illustrated with the help of an actual prototype. The image quality metrics of this prototype are characterized and compared with a multi-detector CT (MDCT). (orig.)

  19. Natural Programming: Project Overview and Proposal

    National Research Council Canada - National Science Library

    Myers, Brad

    1998-01-01

    .... The Natural Programming Project is developing general principles, methods, and programming language designs that will significantly reduce the amount of learning and effort needed to write programs...

  20. The application of safeguards design principles to the spent fuel bundle counter for 600 MW

    International Nuclear Information System (INIS)

    Stirling, A.J.; Allen, V.H.

    1978-10-01

    The irradiated fuel bundle counters for CANDU 600 MW reactors provide the IAEA with a secure and independent means of estimating the inventory of the spent fuel storage bay at each inspection. Their function is straightforward: to count the bundles entering the storage area through the normal transfer ports. However, location, reliability, security and operating requirements make them highly ΣintelligentΣ instruments which have required a major development program. Moreover, the bundle counters incorporate principles which apply to many unattended safeguards instruments. For example, concealing the operating status from potential diverters eases reliability specifications, continuous self-checking gives the inspector confidence in the readout, independence from continuous station services improves tamper resistance, and the detailed data display provides tamper indication and a high level of credibility. Each irradiated fuel bundle counter uses four Geiger counters to detect the passage of fuel bundles as they pass sequentially through the field-of-view. A Microprocessor analyzes the sequence of the Geiger counter signals and determines the number and direction of bundles transferred. The readout for IAEA inspectors includes both a tally and a printed log. The printer is also used to alert the inspector to abnomal fuel movements, tampering, Geiger counter failures and contamination of the fuel transfer mechanism. (author)

  1. USING THE PRINCIPLES OF TRANSFORMATION IN THE DEVELOPMENT OF NEW DESIGN CLOTHES-MAKING FOR WOMEN

    Directory of Open Access Journals (Sweden)

    IROVAN Marcela

    2016-05-01

    Full Text Available The transformable garments represent an actual group in the assortment of contemporary clothing, providing wide possibilities of obtaining multifunctional shapes. The work presents the results of theoretical and applied research in the design of garments with flexible structure for women. The scope of study consists in the analysis of possibilities to develop modern assortments of garments for women by using morphological transformation techniques. The transformable products include an ensemble of garments designed with diverse techniques and methods, both traditional and non-traditional. The morphological transformation techniques are based on the principles of reconstruction and transformation, facilitating the transformation of one product shape into another and transformation of elements in the interior of the same shape. The study has defined several development directions for transformable products in the actual wardrobe: products made with two different texture, color and structure faces; products with attachable or detachable elements; products with a separate structure that by location, wrapping or connection of elements allow to obtain diverse shapes; products with changing shapes with the aid of various types of accessories; multifunctional product elements. The experimental studies were aimed at the elaboration of assortments of garments for women by applying the morphological transformation procedures with elaboration and manufacturing of models of transformable skirts for women. The transformable models demonstrate the universality of products, their functional possibilities, capacity to change the external appearance and aesthetic properties. When designing women’s skirts one may use all types of transformation, several types of transformation may be used in one product simultaneously thus achieving several functional scopes.

  2. Design and exploration of semiconductors from first principles: A review of recent advances

    Science.gov (United States)

    Oba, Fumiyasu; Kumagai, Yu

    2018-06-01

    Recent first-principles approaches to semiconductors are reviewed, with an emphasis on theoretical insight into emerging materials and in silico exploration of as-yet-unreported materials. As relevant theory and methodologies have developed, along with computer performance, it is now feasible to predict a variety of material properties ab initio at the practical level of accuracy required for detailed understanding and elaborate design of semiconductors; these material properties include (i) fundamental bulk properties such as band gaps, effective masses, dielectric constants, and optical absorption coefficients; (ii) the properties of point defects, including native defects, residual impurities, and dopants, such as donor, acceptor, and deep-trap levels, and formation energies, which determine the carrier type and density; and (iii) absolute and relative band positions, including ionization potentials and electron affinities at semiconductor surfaces, band offsets at heterointerfaces between dissimilar semiconductors, and Schottky barrier heights at metal–semiconductor interfaces, which are often discussed systematically using band alignment or lineup diagrams. These predictions from first principles have made it possible to elucidate the characteristics of semiconductors used in industry, including group III–V compounds such as GaN, GaP, and GaAs and their alloys with related Al and In compounds; amorphous oxides, represented by In–Ga–Zn–O transparent conductive oxides (TCOs), represented by In2O3, SnO2, and ZnO; and photovoltaic absorber and buffer layer materials such as CdTe and CdS among group II–VI compounds and chalcopyrite CuInSe2, CuGaSe2, and CuIn1‑ x Ga x Se2 (CIGS) alloys, in addition to the prototypical elemental semiconductors Si and Ge. Semiconductors attracting renewed or emerging interest have also been investigated, for instance, divalent tin compounds, including SnO and SnS; wurtzite-derived ternary compounds such as ZnSnN2 and Cu

  3. 75 FR 8239 - School Food Safety Program Based on Hazard Analysis and Critical Control Point Principles (HACCP...

    Science.gov (United States)

    2010-02-24

    ... (HACCP); Approval of Information Collection Request AGENCY: Food and Nutrition Service, USDA. ACTION... Safety Program Based on Hazard Analysis and Critical Control Point Principles (HACCP) was published on... must be based on the (HACCP) system established by the Secretary of Agriculture. The food safety...

  4. THE RELATIONSHIP BETWEEN PEDAGOGICAL FORMATION TRAINING CERTIFICATE PROGRAM PROSPECTIVE TEACHERS' CRITICAL THINKING ATTITUDES AND THEIR PERCEPTIONS ON PROFESSIONAL ETHICAL PRINCIPLES

    OpenAIRE

    Birsel Aybek; Serkan Aslan

    2017-01-01

    This research aims to analyze the relationship between pedagogical formation training certificate program prospective teachers’ critical thinking attitudes and their perceptions on professional ethical principles. The study used relational screening model and convenience sampling method which is one of the purposeful sampling methods. The participants consisted of 393 prospective teachers from different majors such as mathematics, physics, chemistry, health, biology, philosophy, religious cul...

  5. A CAD (Classroom Assessment Design) of a Computer Programming Course

    Science.gov (United States)

    Hawi, Nazir S.

    2012-01-01

    This paper presents a CAD (classroom assessment design) of an entry-level undergraduate computer programming course "Computer Programming I". CAD has been the product of a long experience in teaching computer programming courses including teaching "Computer Programming I" 22 times. Each semester, CAD is evaluated and modified…

  6. Program computes single-point failures in critical system designs

    Science.gov (United States)

    Brown, W. R.

    1967-01-01

    Computer program analyzes the designs of critical systems that will either prove the design is free of single-point failures or detect each member of the population of single-point failures inherent in a system design. This program should find application in the checkout of redundant circuits and digital systems.

  7. Canadian nuclear power principles for beyond design basis events - supporting rationale

    International Nuclear Information System (INIS)

    Elliott, M.; Newman, G.; Bhaloo, A.

    2014-01-01

    The development of the following principles and their rationale began during a special Chief Nuclear Engineers forum held on March 25th, 2013 in Toronto. These principles are intended to provide guidance to the Canadian Nuclear Power Industry in developing responses to the lessons learned from the Fukushima event of March 2011. These principles were accepted and signed off by the Chief Nuclear Officers of each of the three utilities in August 2013 and were presented to the CNSC at a public hearing on August 21, 2013. This document provides the underlying rationale for the principles. (author)

  8. Canadian nuclear power principles for beyond design basis events - supporting rationale

    Energy Technology Data Exchange (ETDEWEB)

    Elliott, M. [OPG Nuclear, Ontario (Canada); Newman, G. [Bruce Power, Ontario (Canada); Bhaloo, A. [New Brunswick Power, New Brunswick (Canada)

    2014-09-15

    The development of the following principles and their rationale began during a special Chief Nuclear Engineers forum held on March 25th, 2013 in Toronto. These principles are intended to provide guidance to the Canadian Nuclear Power Industry in developing responses to the lessons learned from the Fukushima event of March 2011. These principles were accepted and signed off by the Chief Nuclear Officers of each of the three utilities in August 2013 and were presented to the CNSC at a public hearing on August 21, 2013. This document provides the underlying rationale for the principles. (author)

  9. Canadian nuclear power principles for beyond design basis events - supporting rationale

    Energy Technology Data Exchange (ETDEWEB)

    Elliott, M. [Ontario Power Generation Nuclear, Pickering, ON (Canada); Newman, G. [Bruce Power, Tiverton, ON (Canada); Bhaloo, A. [New Brunswick Power, Fredericton, NB (Canada)

    2014-07-01

    The development of the following principles and their rationale began during a special Chief Nuclear Engineers forum held on March 25th, 2013 in Toronto. These principles are intended to provide guidance to the Canadian Nuclear Power Industry in developing responses to the lessons learned from the Fukushima event of March 2011. These principles were accepted and signed off by the Chief Nuclear Officers of each of the three utilities in August 2013 and were presented to the CNSC at a public hearing on August 21, 2013. This document provides the underlying rationale for the principles. (author)

  10. Network innovation through OpenFlow and SDN principles and design

    CERN Document Server

    Hu, Fei

    2014-01-01

    FUNDAMENTALSSDN /OpenFlow: Concepts and Applications; Ashley Gerrity and Fei HuAn OpenFlow Network Design Cycle; Pedro A. Aranda Gutiřrez and Diego R. LopezDESIGNIP Source Address Validation Solution with OpenFlow Extension and OpenRouter; Jun BiLanguage and Programming in SDN /OpenFlow; Muhammad Farooq and Fei HuControl and Management Software for SDNs; Natalia Castro Fernandes and Luiz Claudio Schara MagalhêsController Architecture and Performance in Software-Defined Networks; Ting Zhang and Fei HuMobile Applications on Global Clouds Using OpenFlow and Software-Defined Networking; Subharth

  11. Biotechnology by Design: An Introductory Level, Project-Based, Synthetic Biology Laboratory Program for Undergraduate Students†

    OpenAIRE

    Beach, Dale L.; Alvarez, Consuelo J.

    2015-01-01

    Synthetic biology offers an ideal opportunity to promote undergraduate laboratory courses with research-style projects, immersing students in an inquiry-based program that enhances the experience of the scientific process. We designed a semester-long, project-based laboratory curriculum using synthetic biology principles to develop a novel sensory device. Students develop subject matter knowledge of molecular genetics and practical skills relevant to molecular biology, recombinant DNA techniq...

  12. A review of low carbon fuel policies: Principles, program status and future directions

    International Nuclear Information System (INIS)

    Yeh, Sonia; Witcover, Julie; Lade, Gabriel E.; Sperling, Daniel

    2016-01-01

    A low carbon fuel standard (LCFS) is a market-based policy that specifies declining standards for the average lifecycle fuel carbon intensity (AFCI) of transportation fuels sold in a region. This paper: (i) compares transportation fuel carbon policies in terms of their economic efficiency, fuel price impacts, greenhouse gas emission reductions, and incentives for innovation; (ii) discusses key regulatory design features of LCFS policies; and (iii) provides an update on the implementation status of LCFS policies in California, the European Union, British Columbia, and Oregon. The economics literature finds that an intensity standard implicitly taxes emissions and subsidizes output. The output subsidy results in an intensity standard being inferior to a carbon tax in a first-best world, although the inefficiency can be corrected with a properly designed consumption tax (or mitigated by a properly designed carbon tax or cap-and-trade program). In California, from 2011 to 2015 the share of alternative fuels in the regulated transportation fuels pool increased by 30%, and the reported AFCI of all alternative fuels declined 21%. LCFS credit prices have varied considerably, rising to above $100/credit in the first half of 2016. LCFS programs in other jurisdictions share many features with California's, but have distinct provisions as well. - Highlights: • LCFS is a market-based policy that sets standards for carbon intensity of fuels. • We compare efficiency, price impacts, GHG emissions, and innovation of C policies. • In California, reported carbon intensity of alternative fuels declined 21% 2011–2015. • LCFS credit prices have varied considerably, rising to above $100/credit in the first half of 2016. • Other LCFS programs share many features with CA's and have distinct provisions.

  13. Novel geometrical concept of a high-performance brain PET scanner. Principle, design and performance estimates

    International Nuclear Information System (INIS)

    Seguinot, J.; Braem, A.; Chesi, E.

    2006-01-01

    We present the principle, a possible implementation and performance estimates of a novel geometrical concept for a high-resolution positron emission tomograph. The concept, which can be for example implemented in a brain PET device, promises to lead to an essentially parallax-free 3D image reconstruction with excellent spatial resolution and contrast, uniform over the complete field of view. The key components are matrices of long axially oriented scintillator crystals which are read out at both extremities by segmented Hybrid Photon Detectors. We discuss the relevant design considerations for a 3D axial PET camera module, motivate parameter and material choices, and estimate its performance in terms of spatial and energy resolution. We support these estimates by Monte Carlo simulations and in some cases by first experimental results. From the performance of a camera module, we extrapolate to the reconstruction resolution of a 3D axial PET scanner in a semi-analytical way and compare it to an existing state-of-the art brain PET device. We finally describe a dedicated data acquisition system, capable to fully exploit the advantages of the proposed concept

  14. Structural design principles of complex bird songs: a network-based approach.

    Directory of Open Access Journals (Sweden)

    Kazutoshi Sasahara

    Full Text Available Bird songs are acoustic communication signals primarily used in male-male aggression and in male-female attraction. These are often monotonous patterns composed of a few phrases, yet some birds have extremely complex songs with a large phrase repertoire, organized in non-random fashion with discernible patterns. Since structure is typically associated with function, the structures of complex bird songs provide important clues to the evolution of animal communication systems. Here we propose an efficient network-based approach to explore structural design principles of complex bird songs, in which the song networks--transition relationships among different phrases and the related structural measures--are employed. We demonstrate how this approach works with an example using California Thrasher songs, which are sequences of highly varied phrases delivered in succession over several minutes. These songs display two distinct features: a large phrase repertoire with a 'small-world' architecture, in which subsets of phrases are highly grouped and linked with a short average path length; and a balanced transition diversity amongst phrases, in which deterministic and non-deterministic transition patterns are moderately mixed. We explore the robustness of this approach with variations in sample size and the amount of noise. Our approach enables a more quantitative study of global and local structural properties of complex bird songs than has been possible to date.

  15. Design Principles of A Sigma-delta Flux-gate Magnetometer

    Science.gov (United States)

    Magnes, W.; Valavanoglou, A.; Pierce, D.; Frank, A.; Schwingenschuh, K.

    A state-of-the-art flux-gate magnetometer is characterised by magnetic field resolution of several pT in a wide frequency range, low power consumption, low weight and high robustness. Therefore, flux-gate magnetometers are frequently used for ground-based Earth's field observation as well as for measurements aboard scientific space missions. But both traditional analogue and recently developed digital flux-gate magnetometers need low power and high-resolution analogue-to-digital converters for signal quan- tization. The disadvantage of such converters is the low radiation hardness. This fact has led to the idea of combining a traditional analogue flux-gate regulation circuit with that of a discretely realized sigma-delta converter in order to get a radiation hard and further miniaturized magnetometer. The name sigma-delta converter is derived from putting an integrator in front of a 1-bit delta modulator which forms the sigma-delta loop. It is followed by a digital decimation filter realized in a field-programmable gate array (FPGA). The flux-gate regulation and the sigma-delta loop are quite similar in the way of realizing the integrator and feedback circuit, which makes it easy to com- bine these two systems. The presented talk deals with the design principles and the results of a first bread board model.

  16. Principles underlying the design of "The Number Race", an adaptive computer game for remediation of dyscalculia

    Directory of Open Access Journals (Sweden)

    Cohen Laurent

    2006-05-01

    Full Text Available Abstract Background Adaptive game software has been successful in remediation of dyslexia. Here we describe the cognitive and algorithmic principles underlying the development of similar software for dyscalculia. Our software is based on current understanding of the cerebral representation of number and the hypotheses that dyscalculia is due to a "core deficit" in number sense or in the link between number sense and symbolic number representations. Methods "The Number Race" software trains children on an entertaining numerical comparison task, by presenting problems adapted to the performance level of the individual child. We report full mathematical specifications of the algorithm used, which relies on an internal model of the child's knowledge in a multidimensional "learning space" consisting of three difficulty dimensions: numerical distance, response deadline, and conceptual complexity (from non-symbolic numerosity processing to increasingly complex symbolic operations. Results The performance of the software was evaluated both by mathematical simulations and by five weeks of use by nine children with mathematical learning difficulties. The results indicate that the software adapts well to varying levels of initial knowledge and learning speeds. Feedback from children, parents and teachers was positive. A companion article 1 describes the evolution of number sense and arithmetic scores before and after training. Conclusion The software, open-source and freely available online, is designed for learning disabled children aged 5–8, and may also be useful for general instruction of normal preschool children. The learning algorithm reported is highly general, and may be applied in other domains.

  17. Principles of design and software development models of ontological-driven computer systems

    OpenAIRE

    Palagin, A. V.; Petrenko, N. G.; Velychko, V. Yu.; Malakhov, K. S.; Karun, O. V.

    2018-01-01

    This paper describes the design principles of methodology of knowledge-oriented information systems based on ontological approach. Such systems implement technology subject-oriented extraction of knowledge from the set of natural language texts and their formal and logical presentation and application processing В работе описаны основы методологии проектирования знание-ориентированных информационных систем на основе онтологического подхода. Такие системы реализуют технологию извлечения пре...

  18. Design of a speed meter interferometer proof-of-principle experiment

    International Nuclear Information System (INIS)

    Gräf, C; Barr, B W; Bell, A S; Campbell, F; Cumming, A V; Gordon, N A; Hammond, G D; Hennig, J; Houston, E A; Huttner, S H; Jones, R A; Leavey, S S; Macarthur, J; Marwick, M; Rigby, S; Sorazu, B; Spencer, A; Danilishin, S L; Lück, H; Schilling, R

    2014-01-01

    The second generation of large scale interferometric gravitational wave (GW) detectors will be limited by quantum noise over a wide frequency range in their detection band. Further sensitivity improvements for future upgrades or new detectors beyond the second generation motivate the development of measurement schemes to mitigate the impact of quantum noise in these instruments. Two strands of development are being pursued to reach this goal, focusing both on modifications of the well-established Michelson detector configuration and development of different detector topologies. In this paper, we present the design of the world's first Sagnac speed meter (SSM) interferometer, which is currently being constructed at the University of Glasgow. With this proof-of-principle experiment we aim to demonstrate the theoretically predicted lower quantum noise in a Sagnac interferometer compared to an equivalent Michelson interferometer, to qualify SSM for further research towards an implementation in a future generation large scale GW detector, such as the planned Einstein telescope observatory. (paper)

  19. ICT FOR HIGH SCHOOL STUDENTS’ RESEARCHES: DESIGN PRINCIPLES, TRENDS AND EXPERIENCE OF USE

    Directory of Open Access Journals (Sweden)

    Oleksandr Yu. Burov

    2016-02-01

    Full Text Available The article describes the principles of ICT design and technology for research in high school, including two subsystems - assessment of intellectual abilities and the selection of students for the intellectual professions, as well as the modeling of cognitive and perceptual activity in the conditions of influence of various factors (internal and external. The description of the psychological tests used in the proposed ICT has been given. It is described an example of student research projects in the field of natural and mathematical sciences on the basis of experimental studies using the developed ICT: identifying the effect of solar activity and geomagnetic field on a physiological state and cognitive performance, communication chronotype and success of high school students learning, appearance of bifurcation in the performance of cognitive tasks rate. These results demonstrated the students' ability to perform using this ICT not only the research training projects, but also the field research to yield new knowledge in mathematics, physics, psychology, medicine and physiology.

  20. PROJECTING PRINCIPLES OF «MATHEMATICAL AND PHYSICAL BASICS IN INFORMATICS» MODULE AS PART OF A UNIVERSAL BACCALAUREATE PROGRAM

    Directory of Open Access Journals (Sweden)

    E. K. Samerkhanova

    2016-01-01

    Full Text Available This article is a presentation of “Mathematical and Physical Basics in Informatics” Module projected as part of universal baccalaureate model realized in Minin State Pedagogical University, Nizhny Novgorod, within the educational program for an extended group of qualifications “Informatics and Calculating Machines”. Module authors defined a strategy for baccalaureates preparation in the field of informational technology, which is realized due to a bunch of principles: education fundamentalization, learning systematization, activity, integration and student-centration. The principle of education fundamentalization requires consolidation of scientific and methodological preparation of students. The principle of learning systematization guarantees formation of students’ holistic ideology. The principle of integration is directed onto qualitative interdisciplinary conversion based on mutual enrichment of knowledge and skills. The principle of activity considers student personality, its formation and growth with respect to practical activity as a special form of psychical activity. The principle of student-centration is displayed as social-humanistic purpose of the educational process.

  1. Design principles for high–pressure force fields: Aqueous TMAO solutions from ambient to kilobar pressures

    Energy Technology Data Exchange (ETDEWEB)

    Hölzl, Christoph; Horinek, Dominik, E-mail: dominik.horinek@ur.de [Institut für Physikalische und Theoretische Chemie, Universität Regensburg, 93040 Regensburg (Germany); Kibies, Patrick; Frach, Roland; Kast, Stefan M., E-mail: stefan.kast@tu-dortmund.de [Physikalische Chemie III, Technische Universität Dortmund, 44227 Dortmund (Germany); Imoto, Sho, E-mail: sho.imoto@theochem.rub.de; Marx, Dominik [Lehrstuhl für Theoretische Chemie, Ruhr-Universität Bochum, 44780 Bochum (Germany); Suladze, Saba; Winter, Roland [Physikalische Chemie I, Technische Universität Dortmund, 44227 Dortmund (Germany)

    2016-04-14

    Accurate force fields are one of the major pillars on which successful molecular dynamics simulations of complex biomolecular processes rest. They have been optimized for ambient conditions, whereas high-pressure simulations become increasingly important in pressure perturbation studies, using pressure as an independent thermodynamic variable. Here, we explore the design of non-polarizable force fields tailored to work well in the realm of kilobar pressures – while avoiding complete reparameterization. Our key is to first compute the pressure-induced electronic and structural response of a solute by combining an integral equation approach to include pressure effects on solvent structure with a quantum-chemical treatment of the solute within the embedded cluster reference interaction site model (EC-RISM) framework. Next, the solute’s response to compression is taken into account by introducing pressure-dependence into selected parameters of a well-established force field. In our proof-of-principle study, the full machinery is applied to N,N,N-trimethylamine-N-oxide (TMAO) in water being a potent osmolyte that counteracts pressure denaturation. EC-RISM theory is shown to describe well the charge redistribution upon compression of TMAO(aq) to 10 kbar, which is then embodied in force field molecular dynamics by pressure-dependent partial charges. The performance of the high pressure force field is assessed by comparing to experimental and ab initio molecular dynamics data. Beyond its broad usefulness for designing non-polarizable force fields for extreme thermodynamic conditions, a good description of the pressure-response of solutions is highly recommended when constructing and validating polarizable force fields.

  2. Design principles for high-pressure force fields: Aqueous TMAO solutions from ambient to kilobar pressures.

    Science.gov (United States)

    Hölzl, Christoph; Kibies, Patrick; Imoto, Sho; Frach, Roland; Suladze, Saba; Winter, Roland; Marx, Dominik; Horinek, Dominik; Kast, Stefan M

    2016-04-14

    Accurate force fields are one of the major pillars on which successful molecular dynamics simulations of complex biomolecular processes rest. They have been optimized for ambient conditions, whereas high-pressure simulations become increasingly important in pressure perturbation studies, using pressure as an independent thermodynamic variable. Here, we explore the design of non-polarizable force fields tailored to work well in the realm of kilobar pressures--while avoiding complete reparameterization. Our key is to first compute the pressure-induced electronic and structural response of a solute by combining an integral equation approach to include pressure effects on solvent structure with a quantum-chemical treatment of the solute within the embedded cluster reference interaction site model (EC-RISM) framework. Next, the solute's response to compression is taken into account by introducing pressure-dependence into selected parameters of a well-established force field. In our proof-of-principle study, the full machinery is applied to N,N,N-trimethylamine-N-oxide (TMAO) in water being a potent osmolyte that counteracts pressure denaturation. EC-RISM theory is shown to describe well the charge redistribution upon compression of TMAO(aq) to 10 kbar, which is then embodied in force field molecular dynamics by pressure-dependent partial charges. The performance of the high pressure force field is assessed by comparing to experimental and ab initio molecular dynamics data. Beyond its broad usefulness for designing non-polarizable force fields for extreme thermodynamic conditions, a good description of the pressure-response of solutions is highly recommended when constructing and validating polarizable force fields.

  3. Design principles for high–pressure force fields: Aqueous TMAO solutions from ambient to kilobar pressures

    International Nuclear Information System (INIS)

    Hölzl, Christoph; Horinek, Dominik; Kibies, Patrick; Frach, Roland; Kast, Stefan M.; Imoto, Sho; Marx, Dominik; Suladze, Saba; Winter, Roland

    2016-01-01

    Accurate force fields are one of the major pillars on which successful molecular dynamics simulations of complex biomolecular processes rest. They have been optimized for ambient conditions, whereas high-pressure simulations become increasingly important in pressure perturbation studies, using pressure as an independent thermodynamic variable. Here, we explore the design of non-polarizable force fields tailored to work well in the realm of kilobar pressures – while avoiding complete reparameterization. Our key is to first compute the pressure-induced electronic and structural response of a solute by combining an integral equation approach to include pressure effects on solvent structure with a quantum-chemical treatment of the solute within the embedded cluster reference interaction site model (EC-RISM) framework. Next, the solute’s response to compression is taken into account by introducing pressure-dependence into selected parameters of a well-established force field. In our proof-of-principle study, the full machinery is applied to N,N,N-trimethylamine-N-oxide (TMAO) in water being a potent osmolyte that counteracts pressure denaturation. EC-RISM theory is shown to describe well the charge redistribution upon compression of TMAO(aq) to 10 kbar, which is then embodied in force field molecular dynamics by pressure-dependent partial charges. The performance of the high pressure force field is assessed by comparing to experimental and ab initio molecular dynamics data. Beyond its broad usefulness for designing non-polarizable force fields for extreme thermodynamic conditions, a good description of the pressure-response of solutions is highly recommended when constructing and validating polarizable force fields.

  4. The principle of phase stability and the accelerator program at Berkeley, 1945--1954

    International Nuclear Information System (INIS)

    Lofgren, E.J.

    1994-07-01

    The discovery of the Principle of Phase Stability by Vladimir Veksler and Edwin McMillian and the end of the war released a surge of accelerator activity at the Lawrence Berkeley Laboratory (then The University of California Radiation Laboratory). Six accelerators incorporating the Principle of Phase Stability were built in the period 1945--1954

  5. Financial Sector Assessment Program : Malaysia - IOSCO Objectives and Principles of Securities Regulation

    OpenAIRE

    World Bank; International Monetary Fund

    2013-01-01

    The Securities Commission Malaysia (SC), as the supervisor of the capital markets, has developed a robust supervisory framework that exhibits high levels of implementation of the International Organization of Securities Commissions Objectives and Principles of Securities Regulation (IOSCO Principles) in most areas. The SC's independence will be buttressed by some changes to the legal provi...

  6. The organizational structure and governing principles of the Food and Drug Administration's Mini-Sentinel pilot program.

    Science.gov (United States)

    Forrow, Susan; Campion, Daniel M; Herrinton, Lisa J; Nair, Vinit P; Robb, Melissa A; Wilson, Marcus; Platt, Richard

    2012-01-01

    The US Food and Drug Administration's Mini-Sentinel pilot program is developing an organizational structure as well as principles and policies to govern its operations. These will inform the structure and function of the eventual Sentinel System. Mini-Sentinel is a collaboration that includes 25 participating institutions. We describe the program's current organizational structure and its major principles and policies. The organization includes a coordinating center with program leadership provided by a principal investigator; a planning board and subcommittees; an operations center; and data, methods, and protocol cores. Ad hoc workgroups are created as needed. A privacy panel advises about protection of individual health information. Principles and policies are intended to ensure that Mini-Sentinel conforms to the principles of fair information practices, protects the privacy of individual health information, maintains the security and integrity of data, assures the confidentiality of proprietary information, provides accurate and timely communications, prevents or manages conflicts of interest, and preserves respect for intellectual property rights. Copyright © 2012 John Wiley & Sons, Ltd.

  7. SASD-tools for program design

    International Nuclear Information System (INIS)

    Gather, K.S.

    1989-01-01

    An overview of Structured Analysis Structured Design (SASD) methodology is given. Some emphasis is put on the time needed to start in a HEP environment with software design methodologies, and on the motivation for SASD. The need for tools is indicated, and examples of their usefulness in analysis and design steps are discussed. Limitations of certain design methods are indicated and additional tools are briefly discussed. Criteria for the selection of tools to be used in large systems design are discussed, and some attention is given to implications for management structures. (orig.)

  8. Computer Aided Design System for Developing Musical Fountain Programs

    Institute of Scientific and Technical Information of China (English)

    刘丹; 张乃尧; 朱汉城

    2003-01-01

    A computer aided design system for developing musical fountain programs was developed with multiple functions such as intelligent design, 3-D animation, manual modification and synchronized motion to make the development process more efficient. The system first analyzed the music form and sentiment using many basic features of the music to select a basic fountain program. Then, this program is simulated with 3-D animation and modified manually to achieve the desired results. Finally, the program is transformed to a computer control program to control the musical fountain in time with the music. A prototype system for the musical fountain was also developed. It was tested with many styles of music and users were quite satisfied with its performance. By integrating various functions, the proposed computer aided design system for developing musical fountain programs greatly simplified the design of the musical fountain programs.

  9. Regulatory principles, criteria and guidelines for site selection, design, construction and operation of uranium tailings retention systems

    International Nuclear Information System (INIS)

    Coady, J.R.; Henry, L.C.

    1978-01-01

    Principles, criteria and guidelines developed by the Atomic Energy Control Board for the management of uranium mill tailings are discussed. The application of these concepts is considered in relation to site selection, design and construction, operation and decommissioning of tailings retention facilities

  10. Improving the Quality of Online Discussion: The Effects of Strategies Designed Based on Cognitive Load Theory Principles

    Science.gov (United States)

    Darabi, Aubteen; Jin, Li

    2013-01-01

    This article focuses on heavy cognitive load as the reason for the lack of quality associated with conventional online discussion. Using the principles of cognitive load theory, four online discussion strategies were designed specifically aiming at reducing the discussants' cognitive load and thus enhancing the quality of their online discussion.…

  11. Designing for Discovery Learning of Complexity Principles of Congestion by Driving Together in the TrafficJams Simulation

    Science.gov (United States)

    Levy, Sharona T.; Peleg, Ran; Ofeck, Eyal; Tabor, Naamit; Dubovi, Ilana; Bluestein, Shiri; Ben-Zur, Hadar

    2018-01-01

    We propose and evaluate a framework supporting collaborative discovery learning of complex systems. The framework blends five design principles: (1) individual action: amidst (2) social interactions; challenged with (3) multiple tasks; set in (4) a constrained interactive learning environment that draws attention to (5) highlighted target…

  12. Design and Development of a Learning Design Virtual Internship Program

    Science.gov (United States)

    Ruggiero, Dana; Boehm, Jeff

    2016-01-01

    Incorporation of practical experience in learning design and technology education has long been accepted as an important step in the developmental process of future learning designers. The proliferation of adult online education has increased the number of graduate students who are in need of a practical internship placement but have limited…

  13. Designing Camera Networks by Convex Quadratic Programming

    KAUST Repository

    Ghanem, Bernard; Wonka, Peter; Cao, Yuanhao

    2015-01-01

    be formulated mathematically as a convex binary quadratic program (BQP) under linear constraints. Moreover, we propose an optimization strategy with a favorable trade-off between speed and solution quality. Our solution

  14. Principles of transistor circuits introduction to the design of amplifiers, receivers and digital circuits

    CERN Document Server

    Amos, S W

    2013-01-01

    Principles of Transistor Circuits: Sixth Edition discusses the principles, concepts, and practices involved integrated circuits. The current edition includes up-to-date circuits, the section on thyristors has been revised to give more information on modern types, and dated information has been eliminated. The book covers related topics such as semiconductors and junction diodes; the principles behind transistors; and common amplifiers. The book also covers bias and DC stabilization; large-signal and small-signal AF amplifiers; DC and pulse amplifiers; sinusoidal oscillators; pulse and sawtooth

  15. The Andrews’ Principles of Risk, Need, and Responsivity as Applied in Drug Abuse Treatment Programs: Meta-Analysis of Crime and Drug Use Outcomes

    Science.gov (United States)

    Prendergast, Michael L.; Pearson, Frank S.; Podus, Deborah; Hamilton, Zachary K.; Greenwell, Lisa

    2013-01-01

    Objectives The purpose of the present meta-analysis was to answer the question: Can the Andrews principles of risk, needs, and responsivity, originally developed for programs that treat offenders, be extended to programs that treat drug abusers? Methods Drawing from a dataset that included 243 independent comparisons, we conducted random-effects meta-regression and ANOVA-analog meta-analyses to test the Andrews principles by averaging crime and drug use outcomes over a diverse set of programs for drug abuse problems. Results For crime outcomes, in the meta-regressions the point estimates for each of the principles were substantial, consistent with previous studies of the Andrews principles. There was also a substantial point estimate for programs exhibiting a greater number of the principles. However, almost all of the 95% confidence intervals included the zero point. For drug use outcomes, in the meta-regressions the point estimates for each of the principles was approximately zero; however, the point estimate for programs exhibiting a greater number of the principles was somewhat positive. All of the estimates for the drug use principles had confidence intervals that included the zero point. Conclusions This study supports previous findings from primary research studies targeting the Andrews principles that those principles are effective in reducing crime outcomes, here in meta-analytic research focused on drug treatment programs. By contrast, programs that follow the principles appear to have very little effect on drug use outcomes. Primary research studies that experimentally test the Andrews principles in drug treatment programs are recommended. PMID:24058325

  16. Cell surface receptors for signal transduction and ligand transport: a design principles study.

    Directory of Open Access Journals (Sweden)

    Harish Shankaran

    2007-06-01

    Full Text Available Receptors constitute the interface of cells to their external environment. These molecules bind specific ligands involved in multiple processes, such as signal transduction and nutrient transport. Although a variety of cell surface receptors undergo endocytosis, the systems-level design principles that govern the evolution of receptor trafficking dynamics are far from fully understood. We have constructed a generalized mathematical model of receptor-ligand binding and internalization to understand how receptor internalization dynamics encodes receptor function and regulation. A given signaling or transport receptor system represents a particular implementation of this module with a specific set of kinetic parameters. Parametric analysis of the response of receptor systems to ligand inputs reveals that receptor systems can be characterized as being: i avidity-controlled where the response control depends primarily on the extracellular ligand capture efficiency, ii consumption-controlled where the ability to internalize surface-bound ligand is the primary control parameter, and iii dual-sensitivity where both the avidity and consumption parameters are important. We show that the transferrin and low-density lipoprotein receptors are avidity-controlled, the vitellogenin receptor is consumption-controlled, and the epidermal growth factor receptor is a dual-sensitivity receptor. Significantly, we show that ligand-induced endocytosis is a mechanism to enhance the accuracy of signaling receptors rather than merely serving to attenuate signaling. Our analysis reveals that the location of a receptor system in the avidity-consumption parameter space can be used to understand both its function and its regulation.

  17. Limitations of implementing sustainable construction principles in the conventional South African design approach

    CSIR Research Space (South Africa)

    Sebake, TN

    2008-06-01

    Full Text Available professionals, particularly by architects, in the implementation of sustainability principles in the development of building projects. The aim of the paper is to highlight the limitations of introducing sustainability aspects into the existing South African...

  18. Guided-mode resonant filters and reflectors: Principles, design, and fabrication

    Science.gov (United States)

    Niraula, Manoj

    In this dissertation, we overview the operational principles of these resonant periodic structures, discuss the methods of their design and fabrication, and propose and demonstrate novel functionalities for spatial and spectral filtering, and unpolarized wideband reflection. Fashioned with materially sparse gratings, these optical devices are easy to fabricate and integration friendly compared to their traditional multi-layer counterparts making their research and development critical for practical applications. We study, theoretically, modal properties and parametric dependence of resonant periodic bandpass filters operating in the mid- and near-infrared spectral domains. We investigate three different device architectures consisting of single, double, and triple layers based on all-transparent dielectric and semiconductor thin films. We present three modal coupling configurations forming complex mixtures of two or three distinct leaky modes coupling at different evanescent diffraction orders. Our modal analysis demonstrates key attributes of subwavelength periodic thin-film structures in multiple-modal blending to achieve desired transmission spectra. We provide the first experimental demonstration of high-efficiency and narrow-linewidth resonant bandpass filter applying a single patterned silicon layer on a quartz substrate. Its performance corresponds to bandpass filters requiring 15 traditional Si/SiO2 thin-film layers. The feasibility of sparse narrowband, high-efficiency bandpass filters with extremely wide, flat, and low sidebands is thereby demonstrated. The proposed technology is integration-friendly and opens doors for further development in various disciplines and spectral regions where thin-film solutions are traditionally applied. We demonstrate concurrent spatial and spectral filtering as a new outstanding attribute of resonant periodic devices. This functionality is enabled by a unique, near-complete, reflection state that is discrete in both

  19. Endocrine Disruptor Screening Program (EDSP) Universe of Chemicals and General Validation Principles

    Science.gov (United States)

    This document was developed by the EPA to provide guidance to staff and managers regarding the EDSP universe of chemicals and general validation principles for consideration of computational toxicology tools for chemical prioritization.

  20. Graphical symbols -- Safety colours and safety signs -- Part 1: Design principles for safety signs in workplaces and public areas

    CERN Document Server

    International Organization for Standardization. Geneva

    2002-01-01

    This International Standard establishes the safety identification colours and design principles for safety signs to be used in workplaces and in public areas for the purpose of accident prevention, fire protection, health hazard information and emergency evacuation. It also establishes the basic principles to be applied when developing standards containing safety signs. This part of ISO 3864 is applicable to workplaces and all locations and all sectors where safety-related questions may be posed. However, it is not applicable to the signalling used for guiding rail, road, river, maritime and air traffic and, generally speaking, to those sectors subject to a regulation which may differ.

  1. Classical maple syrup urine disease and brain development: principles of management and formula design.

    Science.gov (United States)

    Strauss, Kevin A; Wardley, Bridget; Robinson, Donna; Hendrickson, Christine; Rider, Nicholas L; Puffenberger, Erik G; Shellmer, Diana; Shelmer, Diana; Moser, Ann B; Morton, D Holmes

    2010-04-01

    managed with MSUD hyperalimentation solution; 86% were precipitated by common infections, especially vomiting and gastroenteritis. The large majority of catabolic illnesses were managed successfully at home using 'sick-day' formula and frequent amino acid monitoring. We conclude that the study formula is safe and effective for the treatment of classical MSUD. In principle, dietary enrichment protects the brain against deficiency of amino acids used for protein accretion, neurotransmitter synthesis, and methyl group transfer. Although the pathophysiology of MSUD can be addressed through rational formula design, this does not replace the need for vigilant clinical monitoring, frequent measurement of the complete amino acid profile, and ongoing dietary adjustments that match nutritional intake to the metabolic demands of growth and illness. Copyright 2009 Elsevier Inc. All rights reserved.

  2. GRAPHIC, time-sharing magnet design computer programs at Argonne

    International Nuclear Information System (INIS)

    Lari, R.J.

    1974-01-01

    This paper describes three magnet design computer programs in use at the Zero Gradient Synchrotron of Argonne National Laboratory. These programs are used in the time sharing mode in conjunction with a Tektronix model 4012 graphic display terminal. The first program in called TRIM, the second MAGNET, and the third GFUN. (U.S.)

  3. Designing health promotion programs by watching the market.

    Science.gov (United States)

    Gelb, B D; Bryant, J M

    1992-03-01

    More health care providers and payors are beginning to see health promotion programs as a significant tool for attracting patients, reducing costs, or both. To help design programs that take into account the values and lifestyles of the target group, naturalistic observation can be useful. The authors illustrate the approach in a study of pipeline workers that provided input for the design of nutrition and smoking cessation programs.

  4. Fundamental Design Principles of Linear Collider Damping Rings, with an Application to CLIC

    CERN Document Server

    Potier, J P

    2000-01-01

    Damping Rings for Linear Colliders have to produce very small normalised emittances at a high repetition rate. A previous paper presented analytical expressions for the equilibrium emittance of an arc cell as a function of the deflection angle per dipole. In addition, an expression for the lattice parameters providing the minimum emittance, and a strategy to stay close to this, were proposed. This analytical approach is extended to the detailed design of Damping Rings, taking into account the straight sections and the damping wigglers. Complete rings, including wiggler and injection insections, were modelled with the MAD [1] program, and their performance was found to be in good agreement with the analytical calculation. With such an approach it is shown that a Damping Ring corresponding to the Compact Linear Collider (CLIC) parameters at 0.5 and 1 TeV centre-of-mass energy, and tunable for two different sets of emittance and injection repetition rate, can be designed using the same ring layout.

  5. Designing Workshops for the Introduction of Lean Enablers to Engineering Programs

    DEFF Research Database (Denmark)

    Gersing, Kilian; Oehmen, Josef; Rebentisch, Eric Rebentisch

    2014-01-01

    There is a large and growing body of knowledge regarding so-called Lean best practices, including most recently in the area of program management and systems engineering. However, there is little elaboration of how these documented best practices are to be introduced to a professional workforce. ...... the Lean principles. The framework was validated through interactions with training professionals in a large automobile manufacturer, and using subject matter experts from a variety of industrial sectors. © 2014 The Authors. Published by Elsevier B.V.......There is a large and growing body of knowledge regarding so-called Lean best practices, including most recently in the area of program management and systems engineering. However, there is little elaboration of how these documented best practices are to be introduced to a professional workforce...... the systematic design of workshops focused specifically on the introduction of Lean principles and practices to program management and the professional workforce in a program environment. The framework is based on a thorough review of literature on training, workshop delivery, and Lean principles, as well...

  6. Design Principles for Covalent Organic Frameworks as Efficient Electrocatalysts in Clean Energy Conversion and Green Oxidizer Production.

    Science.gov (United States)

    Lin, Chun-Yu; Zhang, Lipeng; Zhao, Zhenghang; Xia, Zhenhai

    2017-05-01

    Covalent organic frameworks (COFs), an emerging class of framework materials linked by covalent bonds, hold potential for various applications such as efficient electrocatalysts, photovoltaics, and sensors. To rationally design COF-based electrocatalysts for oxygen reduction and evolution reactions in fuel cells and metal-air batteries, activity descriptors, derived from orbital energy and bonding structures, are identified with the first-principle calculations for the COFs, which correlate COF structures with their catalytic activities. The calculations also predict that alkaline-earth metal-porphyrin COFs could catalyze the direct production of H 2 O 2 , a green oxidizer and an energy carrier. These predictions are supported by experimental data, and the design principles derived from the descriptors provide an approach for rational design of new electrocatalysts for both clean energy conversion and green oxidizer production. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. Design status of heavy ion injector program

    International Nuclear Information System (INIS)

    Ballard, E.O.; Meyer, E.A.; Rutkowski, H.L.; Shurter, R.P.; Van Haaften, F.W.; Riepe, K.B.

    1985-01-01

    Design and development of a sixteen beam, heavy ion injector is in progress at Los Alamos National Laboratory (LANL) to demonstrate the injector technology for the High Temperature Experiment (HTE) proposed by Lawrence Livermore Laboratory (LBL). The injector design provides for individual ion sources mounted to a support plate defining the sixteen beam array. The beamlets are electrostatically accelerated through a series of electrodes inside an evacuated (10 -7 torr) high voltage (HV) accelerating column

  8. Status of the HTR 500 design program

    International Nuclear Information System (INIS)

    Baust, E.; Arndt, E.

    1987-01-01

    Since 1982 BBC/HRB have offered the HTR 500 as the follow-on project of the THTR 300, the first large pebble bed reactor. The technical concept of the HTR-500 largely corresponds to the THTR 300 which has been in operation for almost 2 years now. In developing the design concept of the HTR 500 the ideas and demands of the reactor users in the FRG interested in the HTR have been taken into consideration to a large extent. In 1982 these potential users formed a working group 'Arbeitsgemeinschaft Hochtemperaturreaktor' (AHR), representing 16 power indusry companies and in early 1983, awarded a contract to HRB to perform a conceptual design study on the HTR 500. Within this conceptual design study BBC/HRB developed the safety concept of the HTR 500, prepared a detailed description of the overall power plant, and performed a cost calculation. These activities were completed in 1984. Based on the positive results of this conceptual design study, BBC/HRB are expecting to be granted a design contract by the users company Hochtemperaturreaktor GmbH (HRG) to establish the final complete design plans and documents for the HTR 500. (author)

  9. Program packages for dynamics systems analysis and design

    International Nuclear Information System (INIS)

    Athani, V.V.

    1976-01-01

    The development of computer program packages for dynamic system analysis and design are reported. The purpose of developing these program packages is to take the burden of writing computer programs off the mind of the system engineer and to enable him to concentrate on his main system analysis and design work. Towards this end, four standard computer program packages have been prepared : (1) TFANA - starting from system transfer function this program computes transient response, frequency response, root locus and stability by Routh Hurwitz criterion, (2) TFSYN - classical synthesis using algebraic method of Shipley, (3) MODANA - starting from state equations of the system this program computes solution of state equations, controllability, observability and stability, (4) OPTCON - This program obtains solutions of (i) linear regulator problem, (ii) servomechanism problems and (iii) problem of pole placement. The paper describes these program packages with the help of flowcharts and illustrates their use with the help of examples. (author)

  10. Nigeria; Publication of Financial Sector Assessment Program Documentation––Detailed Assessment of Observance of Insurance Core Principles

    OpenAIRE

    International Monetary Fund

    2013-01-01

    Nigeria undertook a Financial Sector Assessment Program (FSAP), which included a review of the structure of Nigeria’s insurance market and the supervisory framework. The assessment was benchmarked against the Insurance Core Principles (ICPs) issued by the International Association of Insurance Supervisors (IAISs). It is advised that the National Insurance Commission (NAICOM) of Nigeria can expand the objective to include the creation of a fair, safe, and stable insurance sector for the benefi...

  11. Recommendations for sex/gender neuroimaging research: Key principles and implications for research design, analysis and interpretation

    Directory of Open Access Journals (Sweden)

    Gina eRippon

    2014-08-01

    Full Text Available For over a decade, neuroimaging (NI technologies have had an increasing impact in the study of complex cognitive and social processes. In this emerging field of social cognitive neuroscience, a central goal should be to increase the understanding of the interaction between the neurobiology of the individual and the environment in which s/he develops and functions. The study of the relationship between sex and gender could offer a valuable example of such research. We identify here four main principles that should inform NI research. First, the principle of overlap, arising from evidence of significant overlap of female/male distributions on measures of many gendered behaviours. Second, the principle of mosaicism, arising from evidence that for both behaviour and brain, each individual manifests a complex and idiosyncratic combination of feminine and masculine characteristics. Third, the principle of contingency, arising from evidence that female/male behavioural differences are contingent on time, place, social group and context. Fourth, the principle of entanglement, arising from an awareness that the neural phenotypes that NI techniques measure are a function of the interactive and reciprocal influence of biology and environment. These important principles have emerged and become well-established over the past few decades, but their implications are often not reflected in the design and interpretation of NI sex/gender research. We therefore offer a set of guidelines for researchers to ensure that NI sex/gender research is appropriately designed and interpreted. We hope this ‘toolkit’ will also be of use to editorial boards and journal reviewers, as well as those who view, communicate and interpret such research.

  12. Game Programming Course - Creative Design and Development

    Directory of Open Access Journals (Sweden)

    Jaak Henno

    2008-10-01

    Full Text Available Rapid developments of the Electronic Entertainment - computer and video games, virtual environments, the "Games 3.0" revolution - influences also courses about Games and Virtual Environments. In the following is discussed the course “Games and Virtual Environments” presented in the fall 2007 term in Tallinn University of Technology; the main emphasis of the course was not on programming technology, but on understanding games as a special form of communication and exploring specific features of this form.

  13. Principles of expert fuzzy controller design: AI mobile wall climbing robots for decontamination of nuclear power-station

    International Nuclear Information System (INIS)

    Gradetsky, V.G.; Ul'yanov, S.; Slesarev, Y.V.; Pospelov, D.A.

    1994-01-01

    The arrangement principles for a complex control framework of artificial intelligence control systems are introduced. The notions of intelligence levels with the top boundary (intelligence in large) and the bottom boundary (intelligence in small) are defined. A special methodology for the design of an artificial intelligence control system design for the decontamination of a nuclear power plant using a wall climbing robot with different intelligence levels is presented. The application of WARP (Weight Associative Rule Processor) to the design of an automatic fuzzy controller for the fuzzy correction of the motion of the manipulator and WCR is examined

  14. Elmo Bumpy Torus proof of principle, Phase II: Title 1 report. Volume V. Vacuum-pumping system. Preliminary design report

    International Nuclear Information System (INIS)

    1982-01-01

    This report summarizes Title I Preliminary Design of the EBT-P Vacuum Pumping System. The Vacuum Pumping System has been designed by the McDonnell Douglas Astronautics Co. - St. Louis (MDAC). It includes the necessary vacuum pumps and vacuum valves to evacuate the torus, the Mirror Coil Dewars (MC Dewars), and the Gyrotron Magnet Dewars. The pumping ducts, manifolds, and microwave protection system are also included. A summary of the function of each subsystem and a description of its principle components is provided below. The analyses performed during the system design are also identified

  15. Development of design program for air handling units

    Energy Technology Data Exchange (ETDEWEB)

    Ham, J. K.; Kim, J. H.; Kim, Y. K.; Kim, Y. I.; Kang, P. Y. [Hyundai Heavy Industries Co., Ltd., Ulsan (Korea, Republic of)

    2000-07-01

    An Air Handling Unit(AHU) has been usually designed by manual calculations. Drawing works together with design calculations should be redone for every designing work, and also be needed to make some corrections of them. In order to design the AHU more efficiently, an AHU program has been developed. The developed program on the Windows environment is operated by the Graphic User Interface(GUI) realized using the Visual Basic Interpreter. The program provides calculation sheet of coils, weights and pressures in a MS-Excel file format as well as design drawing of the AHU in a auto CAD file format idealized by AutoLISP. Those files of the commercial softwares make easier for a designer to transfer design results to the another company for bid via e-mail.

  16. Development of design program for air handling units

    International Nuclear Information System (INIS)

    Ham, J. K.; Kim, J. H.; Kim, Y. K.; Kim, Y. I.; Kang, P. Y.

    2000-01-01

    An Air Handling Unit(AHU) has been usually designed by manual calculations. Drawing works together with design calculations should be redone for every designing work, and also be needed to make some corrections of them. In order to design the AHU more efficiently, an AHU program has been developed. The developed program on the Windows environment is operated by the Graphic User Interface(GUI) realized using the Visual Basic Interpreter. The program provides calculation sheet of coils, weights and pressures in a MS-Excel file format as well as design drawing of the AHU in a auto CAD file format idealized by AutoLISP. Those files of the commercial softwares make easier for a designer to transfer design results to the another company for bid via e-mail

  17. Development of design program for air handling units

    Energy Technology Data Exchange (ETDEWEB)

    Ham, J.K.; Kim, J.H.; Kim, Y.K.; Kim, Y.I.; Kang, P.Y. [Hyundai Heavy Industries Co., Ltd. (Korea)

    2000-11-01

    An air handling unit(AHU) has been usually designed by manual calculations. Drawing works together with design calculations should be redone for every designing work, and also be needed to make some corrections of them. In order to design the AHU more efficiently, an AHU program has been developed. The developed program on the Windows environment is operated by the graphic user interface(GUI) realized using the Visual Basic Interpreter. The program provides calculation sheet of coils, weights and pressures in a MS-Excel file format as well as design drawing of the AHU in a Auto CAD file format idealized by AutoLISP. Those files of the commercial softwares make easier for a designer to transfer design results to the another company for bid via e-mail. (author). 5 refs., 9 figs., 3 tabs.

  18. PEDAGOGICAL PRINCIPLES OF THE DESIGN AND DEVELOPMENT OF EXPERT TRAINING SYSTEMS

    Directory of Open Access Journals (Sweden)

    Oleh Shevchuk

    2016-05-01

    Full Text Available The articles defines the system of pedagogical principles (centering on an individual, the priority of the pedagogical approach, educational appropriateness of the use of new information technologies; the freedom of choice of the cognitive trajectory; diversity; openness and development; professional orientation; "precedent", the emotional fulfillment of the environment; the distribution of educational material which has to lie on the basis of designingeducational techniques which are based on expert training systems. The gnosiological grounds for the mentioned system of principles are provided.

  19. Principles of transistor circuits introduction to the design of amplifiers, receivers and digital circuits

    CERN Document Server

    Amos, S W

    1990-01-01

    Principles of Transistor Circuits, Seventh Edition discusses the fundamental concepts of transistor circuits. The book is comprised of 16 chapters that cover amplifiers, oscillators, and generators. Chapter 1 discusses semiconductors and junction nodes, while Chapter 2 covers the basic principles of transistors. The subsequent chapters focus on amplifiers, where one of the chapters discusses bias and D.C. The book also talks about sinusoidal oscillators and covers modulators, demodulators, mixers, and receivers. Chapters 13 and 14 discuss pulse generators and sawtooth generators, respectively.

  20. Optics Program Simplifies Analysis and Design

    Science.gov (United States)

    2007-01-01

    Engineers at Goddard Space Flight Center partnered with software experts at Mide Technology Corporation, of Medford, Massachusetts, through a Small Business Innovation Research (SBIR) contract to design the Disturbance-Optics-Controls-Structures (DOCS) Toolbox, a software suite for performing integrated modeling for multidisciplinary analysis and design. The DOCS Toolbox integrates various discipline models into a coupled process math model that can then predict system performance as a function of subsystem design parameters. The system can be optimized for performance; design parameters can be traded; parameter uncertainties can be propagated through the math model to develop error bounds on system predictions; and the model can be updated, based on component, subsystem, or system level data. The Toolbox also allows the definition of process parameters as explicit functions of the coupled model and includes a number of functions that analyze the coupled system model and provide for redesign. The product is being sold commercially by Nightsky Systems Inc., of Raleigh, North Carolina, a spinoff company that was formed by Mide specifically to market the DOCS Toolbox. Commercial applications include use by any contractors developing large space-based optical systems, including Lockheed Martin Corporation, The Boeing Company, and Northrup Grumman Corporation, as well as companies providing technical audit services, like General Dynamics Corporation