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Sample records for program auto refinishing

  1. Assessment of heavy metal exposure around auto body refinishing ...

    African Journals Online (AJOL)

    Workers, soil, plants, air and all environments around these shops are continually exposed by their organic solvents, dust, noise and metal pigments. In the present study, 36 top soil samples including controls were collected from 26 different auto body refinishing shops of the metropolitan city, Karachi. The soil samples ...

  2. Automotive Refinishing Industry: Isocyanates Profile

    Science.gov (United States)

    The isocyanates profile document is part of the DfE Auto Refinishing Shop Project and is intended to provide information on refinishing, control technologies, and regulatory status regarding isocyanate compounds

  3. Auto Body Welding 2 (Course Outline), Automotive Body Repair and Refinishing 1: 9033.04.

    Science.gov (United States)

    Dade County Public Schools, Miami, FL.

    The 90-hour course is a foundation quinmester course in welding for the auto body repairman. The outline consists of seven blocks of instruction (orientation, 6 hours; auto body oxyacetylene welding, 10 hours; electric arc welding equipment, 6 hours; auto body electric arc welding, 8 hours; position welding, 40 hours; electric spot welders, 16…

  4. AUTO

    DEFF Research Database (Denmark)

    Gammelgaard Nielsen, Anders; Aagaard, Tine; Diaz, pauline

    2011-01-01

    AUTO is the first assignment that the students of Architecture are introduced to at the Aarhus school of Architecture. The aim is to give students an understanding of design through a generic working method. This by disassembling a car engine and staging its components through a series of castings...... in plaster. The assignment can be as an implementation of a research into teaching. Thus the study method is based on a generative research method that the present author acquired while conducting research work for a Ph.D project....

  5. AutoBayes Program Synthesis System System Internals

    Science.gov (United States)

    Schumann, Johann Martin

    2011-01-01

    This lecture combines the theoretical background of schema based program synthesis with the hands-on study of a powerful, open-source program synthesis system (Auto-Bayes). Schema-based program synthesis is a popular approach toward program synthesis. The lecture will provide an introduction into this topic and discuss how this technology can be used to generate customized algorithms. The synthesis of advanced numerical algorithms requires the availability of a powerful symbolic (algebra) system. Its task is to symbolically solve equations, simplify expressions, or to symbolically calculate derivatives (among others) such that the synthesized algorithms become as efficient as possible. We will discuss the use and importance of the symbolic system for synthesis. Any synthesis system is a large and complex piece of code. In this lecture, we will study Autobayes in detail. AutoBayes has been developed at NASA Ames and has been made open source. It takes a compact statistical specification and generates a customized data analysis algorithm (in C/C++) from it. AutoBayes is written in SWI Prolog and many concepts from rewriting, logic, functional, and symbolic programming. We will discuss the system architecture, the schema libary and the extensive support infra-structure. Practical hands-on experiments and exercises will enable the student to get insight into a realistic program synthesis system and provides knowledge to use, modify, and extend Autobayes.

  6. Fatal exposure to methylene chloride among bathtub refinishers - United States, 2000-2011.

    Science.gov (United States)

    2012-02-24

    In 2010, the Michigan Fatality Assessment and Control Evaluation program conducted an investigation into the death of a bathtub refinisher who used a methylene chloride-based paint stripping product marketed for use in aircraft maintenance. The program identified two earlier, similar deaths in Michigan. Program staff members notified CDC's National Institute for Occupational Safety and Health (NIOSH), which in turn notified the Occupational Safety and Health Administration (OSHA). In addition to the three deaths, OSHA identified 10 other bathtub refinisher fatalities associated with methylene chloride stripping agents that had been investigated in nine states during 2000-2011. Each death occurred in a residential bathroom with inadequate ventilation. Protective equipment, including a respirator, either was not used or was inadequate to protect against methylene chloride vapor, which has been recognized as potentially fatal to furniture strippers and factory workers but has not been reported previously as a cause of death among bathtub refinishers. Worker safety agencies, public health agencies, methylene chloride-based stripper manufacturers, and trade organizations should communicate the extreme hazards of using methylene chloride-based stripping products in bathtub refinishing to employers, workers, and consumers. Employers should strongly consider alternative methods of bathtub stripping and always ensure worker safety protections that reduce the risk for health hazards to acceptable levels. Employers choosing to use methylene chloride-based stripping products must comply with OSHA's standard to limit methylene chloride exposures to safe levels.

  7. Europe's Auto/Oil 2 program, understanding the cost-benefits of NGV's

    NARCIS (Netherlands)

    Weide, J. van der

    2000-01-01

    In the mid-nineties in Europe, the so-called Auto/Oil 1 Program was carried out. The aim was to improve air quality in urban areas by setting new emissions standards based on improved vehicle and fuel technology. The program was carried out by the auto and oil industry under leadership of the

  8. Enhancing Price Response Programs through Auto-DR: California's 2007 Implementation Experience

    Energy Technology Data Exchange (ETDEWEB)

    Kiliccote, Sila; Wikler, Greg; Chiu, Albert; Piette, Mary Ann; Kiliccote, Sila; Hennage, Dan; Thomas, Chuck

    2007-12-18

    This paper describes automated demand response (Auto-DR) activities, an innovative effort in California to ensure that DR programs produce effective and sustainable impacts. Through the application of automation and communication technologies coupled with well-designed incentives and DR programs such as Critical Peak Pricing (CPP) and Demand Bidding (DBP), Auto-DR is opening up the opportunity for many different types of buildings to effectively participate in DR programs. We present the results of Auto-DR implementation efforts by the three California investor-owned utilities for the Summer of 2007. The presentation emphasizes Pacific Gas and Electric Company's (PG&E) Auto-DR efforts, which represents the largest in the state. PG&E's goal was to recruit, install, test and operate 15 megawatts of Auto-DR system capability. We describe the unique delivery approaches, including optimizing the utility incentive structures designed to foster an Auto-DR service provider community. We also show how PG&E's Critical Peak Pricing (CPP) and Demand Bidding (DBP) options were called and executed under the automation platform. Finally, we show the results of the Auto-DR systems installed and operational during 2007, which surpassed PG&E's Auto-DR goals. Auto-DR is being implemented by a multi-disciplinary team including the California Investor Owned Utilities (IOUs), energy consultants, energy management control system vendors, the Lawrence Berkeley National Laboratory (LBNL), and the California Energy Commission (CEC).

  9. Refinishing contamination floors in Spent Nuclear Fuels storage basins

    Energy Technology Data Exchange (ETDEWEB)

    Huang, F.F.; Moore, F.W.

    1997-07-11

    The floors of the K Basins at the Hanford Site are refinished to make decontamination easier if spills occur as the spent nuclear fuel (SNF) is being unloaded from the basins for shipment to dry storage. Without removing the contaminated existing coating, the basin floors are to be coated with an epoxy coating material selected on the basis of the results of field tests of several paint products. The floor refinishing activities must be reviewed by a management review board to ensure that work can be performed in a controlled manner. Major documents prepared for management board review include a report on maintaining radiation exposure as low as reasonably achievable, a waste management plan, and reports on hazard classification and unreviewed safety questions. To protect personnel working in the radiation zone, Operational Health Physics prescribed the required minimum protective methods and devices in the radiological work permit. Also, industrial hygiene safety must be analyzed to establish respirator requirements for persons working in the basins. The procedure and requirements for the refinishing work are detailed in a work package approved by all safety engineers. After the refinishing work is completed, waste materials generated from the refinishing work must be disposed of according to the waste management plan.

  10. From Single- to Multi-Objective Auto-Tuning of Programs: Advantages and Implications

    Directory of Open Access Journals (Sweden)

    Juan Durillo

    2014-01-01

    Full Text Available Automatic tuning (auto-tuning of software has emerged in recent years as a promising method that tries to automatically adapt the behaviour of a program to attain different performance objectives on a given computing system. This method is gaining momentum due to the increasing complexity of modern multicore-based hardware architectures. Many solutions to auto-tuning have been explored ranging from simple random search to more sophisticate methods like machine learning or evolutionary search. To this day, it is still unclear whether these approaches are general enough to encompass all the complexities of the problem (e.g. search space, parameters influencing the search space, input data sensitivity, etc., or which approach is best suited for a given problem. Furthermore, the growing interest in auto-tuning a program for several objectives is increasing this confusion even further. The goal of this paper is to formally describe the problem addressed by auto-tuning programs and review existing solutions highlighting the advantages and drawbacks of different techniques for single-objective as well as multi-objective auto-tuning approaches.

  11. A Program Recognition and Auto-Testing Approach

    Directory of Open Access Journals (Sweden)

    Wen C. Pai

    2003-06-01

    Full Text Available The goals of the software testing are to assess and improve the quality of the software. An important problem in software testing is to determine whether a program has been tested enough with a testing criterion. To raise a technology to reconstruct the program structure and generating test data automatically will help software developers to improve software quality efficiently. Program recognition and transformation is a technology that can help maintainers to recover the programs' structure and consequently make software testing properly. In this paper, a methodology to follow the logic of a program and transform to the original program graph is proposed. An approach to derive testing paths automatically for a program to test every blocks of the program is provided. A real example is presented to illustrate and prove that the methodology is practicable. The proposed methodology allows developers to recover the programs' design and makes software maintenance properly.

  12. Method of development of the program of forming of parametrical drawings of details in the AutoCAD software product

    Science.gov (United States)

    Alshakova, E. L.

    2017-01-01

    The program in the AutoLISP language allows automatically to form parametrical drawings during the work in the AutoCAD software product. Students study development of programs on AutoLISP language with the use of the methodical complex containing methodical instructions in which real examples of creation of images and drawings are realized. Methodical instructions contain reference information necessary for the performance of the offered tasks. The method of step-by-step development of the program is the basis for training in programming on AutoLISP language: the program draws elements of the drawing of a detail by means of definitely created function which values of arguments register in that sequence in which AutoCAD gives out inquiries when performing the corresponding command in the editor. The process of the program design is reduced to the process of step-by-step formation of functions and sequence of their calls. The author considers the development of the AutoLISP program for the creation of parametrical drawings of details, the defined design, the user enters the dimensions of elements of details. These programs generate variants of tasks of the graphic works performed in educational process of "Engineering graphics", "Engineering and computer graphics" disciplines. Individual tasks allow to develop at students skills of independent work in reading and creation of drawings, as well as 3D modeling.

  13. An Auto-management Thesis Program WebMIS Based on Workflow

    Science.gov (United States)

    Chang, Li; Jie, Shi; Weibo, Zhong

    An auto-management WebMIS based on workflow for bachelor thesis program is given in this paper. A module used for workflow dispatching is designed and realized using MySQL and J2EE according to the work principle of workflow engine. The module can automatively dispatch the workflow according to the date of system, login information and the work status of the user. The WebMIS changes the management from handwork to computer-work which not only standardizes the thesis program but also keeps the data and documents clean and consistent.

  14. Improvement of air quality according to Mobile reduction measures to establish Korean Auto-oil program

    Science.gov (United States)

    Sunwoo, Y.; Jo, H.; Ma, Y.; Kim, S.; Hong, K.; Lim, Y.; Javascript:Setnextpage('sponsor')

    2011-12-01

    The mobile of NOx and PM10 emission of Korea in 2007 accounted for 42%, 23%, respectively (excluded fugitive dust). Seoul highly affected mobile emission which accounted for 46%, 49%, respectively. Korean government ,therefore, established "Special Act for improvement of air quality in Seoul metropolitan area" including mobile emission reduction measures and organized research forum including reformation of fuel and cars, risk assessment, control of greenhouse gas and assessment of air quality to establish Korean Auto-oil program This study quantitatively analyses improvement of air quality in Seoul according to the reformation of fuel and supply of DPF in Korean Auto-oil program. WRF-SMOKE-CMAQ were emploied for this study. SO2, CO, NOx, PM10 and VOCs emission are based on the INTEX-B emission inventory, NH3 were from the REAS emission inventory. Korea emission is derived by CAPSS (Clean Air Policy Support System) data. The reduction through reformation of fuel and supply of DPF is calculated by reduction ratio of air pollutants with strengthen fuel quality standard and number of car supplied DPF, refer to Metropolitan Air Quality Management Office Republic of Korea (2011) in detail. The effect of air quality is quantifiably comparing modeling results which are applied/not applied on the measures. This study will be provided basic data to establish Korean Auto-oil program through quantifying and predicting to improvement of air quality according to the mobile measures. Acknowledgement This research was supported in part by the "Assessment of risk and health benefits considering exposure characteristics of fuel" project sponsored by the Korea Automobile Environmental Association.

  15. Chemical characterization of sanding dust and methylene chloride usage in automotive refinishing: implications for occupational and environmental health.

    Science.gov (United States)

    Enander, Richard T; Gute, David M; Cohen, Howard J; Brown, Linfield C; Desmaris, Anne Marie C; Missaghian, Richard

    2002-01-01

    Surface preparation activities conducted during automotive refinishing present several potential human health and environmental risks. This study examines the chemical composition of vehicle sanding dust and the prevalence of methylene chloride use as a basis for evaluating potential chemical exposures in the work environment, fugitive environmental releases, and take-home toxics. This article reports on the findings of (1) a statewide technology and work practices survey of 353 licensed auto body shops and (2) laboratory analyses of sanding dust representing more than 200 vehicles, 10 commercial body filler compounds, and work shirts worn during vehicle sanding while using nonventilated equipment. Survey data revealed that the majority of shops (78%) do not use ventilated sanding equipment, that most workers (55%) take their work clothes and shoes home at the end of the workday, and that 17% of the respondents used a methylene chloride-based paint stripper as an adjunct to mechanical sanding. Laboratory results showed that Pb, As, Cr, Mn, and Ni were present in the sanding dust at every facility tested. Lead concentrations in sanding dust were found to be highest at facilities that performed complete vehicle refinishing (range 770 to 7300 ppm) and at a collision repair shop that used a high-lead content body filler compound (1800 ppm). Hexavalent chromium also was found in two vocational high school paint dust samples at concentrations of 54 and 710 ppm. When total lead and chromium concentrations reached 7300 and 2300 ppm, respectively, facility sanding dust samples failed the U.S. Environmental Protection Agency's Toxicity Characteristic Leaching Procedure for hazardous waste. Metals found in the sanding dust also were present on the work shirts of technicians-ranging from 0.06 (Cd) to 81 (Mg) microg/inch2 of cloth-who sanded on paint without ventilated equipment. Results suggest that sanding dust and methylene chloride paint strippers used in vehicle

  16. AutoStitcher: An Automated Program for Efficient and Robust Reconstruction of Digitized Whole Histological Sections from Tissue Fragments

    Science.gov (United States)

    Penzias, Gregory; Janowczyk, Andrew; Singanamalli, Asha; Rusu, Mirabela; Shih, Natalie; Feldman, Michael; Stricker, Phillip D.; Delprado, Warick; Tiwari, Sarita; Böhm, Maret; Haynes, Anne-Maree; Ponsky, Lee; Viswanath, Satish; Madabhushi, Anant

    2016-07-01

    In applications involving large tissue specimens that have been sectioned into smaller tissue fragments, manual reconstruction of a “pseudo whole-mount” histological section (PWMHS) can facilitate (a) pathological disease annotation, and (b) image registration and correlation with radiological images. We have previously presented a program called HistoStitcher, which allows for more efficient manual reconstruction than general purpose image editing tools (such as Photoshop). However HistoStitcher is still manual and hence can be laborious and subjective, especially when doing large cohort studies. In this work we present AutoStitcher, a novel automated algorithm for reconstructing PWMHSs from digitized tissue fragments. AutoStitcher reconstructs (“stitches”) a PWMHS from a set of 4 fragments by optimizing a novel cost function that is domain-inspired to ensure (i) alignment of similar tissue regions, and (ii) contiguity of the prostate boundary. The algorithm achieves computational efficiency by performing reconstruction in a multi-resolution hierarchy. Automated PWMHS reconstruction results (via AutoStitcher) were quantitatively and qualitatively compared to manual reconstructions obtained via HistoStitcher for 113 prostate pathology sections. Distances between corresponding fiducials placed on each of the automated and manual reconstruction results were between 2.7%-3.2%, reflecting their excellent visual similarity.

  17. AutoCAD workbook

    CERN Document Server

    Metherell, Phil

    1989-01-01

    AutoCAD Workbook helps new users learn the basics of AutoCad, providing guidance on most of the commonly used functions in which the program operates.This book discusses loading AutoCad and starting a drawing; drawing and erasing lines, circles, and arcs; and setting up the drawing environment. The topics on drawing and editing polylines; entering text and text styles; and layers, linetype, and color are also considered. This publication likewise covers creating and using blocks, hatching and extracting information, dimensioning drawings, 3D visualization, and plotting a drawing. Other

  18. NONPROCESS SOLVENT USE IN THE FURNITURE REFINISHING AND REPAIR INDUSTRY: EVALUATION OF ALTERNATIVE CHEMICAL STRIPPERS

    Science.gov (United States)

    The report gives results of an evaluation of the feasibility of using alternatives to high volatile organic compound/hazardous air pollutant (VOC/HAP) solvent-based, chemical strippers that are currently used in the furniture repair and refinishing industry to remove both traditi...

  19. A hybrid analytical network process and fuzzy goal programming for supplier selection: A case study of auto part maker

    Directory of Open Access Journals (Sweden)

    Hesam Zande Hesami

    2011-10-01

    Full Text Available The aim of this research is to present a hybrid model to select auto part suppliers. The proposed method of this paper uses factor analysis to find the most influencing factors on part maker selection and the results are validated using different statistical tests such as Cronbach's Alpha and Kaiser-Meyer.The hybrid model uses analytical network process to rank different part maker suppliers and fuzzy goal programming to choose the appropriate alternative among various choices. The implementation of the proposed model of this paper is used for a case study of real-world problem and the results are discussed.

  20. AutoCAD 2010 For Dummies

    CERN Document Server

    Byrnes, David

    2009-01-01

    AutoCAD is the hot computer-aided design software known for both its powerful tools and its complexity. AutoCAD 2010 for Dummies is the bestselling guide that walks you through this complicated program so you can build complex 3D technical drawings, edit like a pro, enter new dimensions, and plot with style. AutoCAD 2010 for Dummies helps you navigate the program, use the AutoCAD Design Center, create a basic layout and work with dimension, and put your drawings on the Internet. You'll soon be setting up the AutoCAD environment, using the AutoCAD Ribbon, creating annotation and dimension drawi

  1. Import Auto Technician; Curriculum Guide for the Development of an Import Automobile Technology Program.

    Science.gov (United States)

    East Los Angeles Coll., CA.

    In this curriculum guide, courses in a three-phase community college program for training import automobile technicians are provided. Following an introducation to the guide, the background of the development of the program, the program, the instruction, support for instruction, and the import automobile industry are discussed. Sample options for…

  2. AutoCAD platform customization autolisp

    CERN Document Server

    Ambrosius, Lee

    2014-01-01

    Customize and personalize programs built on the AutoCAD platform AutoLISP is the key to unlocking the secrets of a more streamlined experience using industry leading software programs like AutoCAD, Civil 3D, Plant 3D, and more. AutoCAD Platform Customization: AutoLISP provides real-world examples that show you how to do everything from modifying graphical objects and reading and setting system variables to communicating with external programs. It also features a resources appendix and downloadable datasets and customization examples-tools that ensure swift and easy adoption. Find out how to r

  3. AutoCAD platform customization VBA

    CERN Document Server

    Ambrosius, Lee

    2015-01-01

    Boost productivity and streamline your workflow with expert AutoCAD: VBA programming instruction AutoCAD Platform Customization: VBA is the definitive guide to personalizing AutoCAD and the various programs that run on the AutoCAD platform, including AutoCAD Architecture, Civil 3D, Plant 3D, and more. Written by an Autodesk insider with years of customization and programming experience, this book features detailed discussions backed by real-world examples and easy-to-follow tutorials that illustrate each step in the personalization process. Readers gain expert guidance toward managing layout

  4. AutoMicromanager: a microscopy scripting toolkit for LABVIEW and other programming environments.

    Science.gov (United States)

    Ashcroft, Brian Alan; Oosterkamp, Tjerk

    2010-11-01

    We present a scripting toolkit for the acquisition and analysis of a wide variety of imaging data by integrating the ease of use of various programming environments such as LABVIEW, IGOR PRO, MATLAB, SCILAB, and others. This toolkit is designed to allow the user to quickly program a variety of standard microscopy components for custom microscopy applications allowing much more flexibility than other packages. Included are both programming tools as well as graphical user interface classes allowing a standard, consistent, and easy to maintain scripting environment. This programming toolkit allows easy access to most commonly used cameras, stages, and shutters through the Micromanager project so the scripter can focus on their custom application instead of boilerplate code generation.

  5. AutoMicromanager: A microscopy scripting toolkit for LABVIEW and other programming environments

    Science.gov (United States)

    Ashcroft, Brian Alan; Oosterkamp, Tjerk

    2010-11-01

    We present a scripting toolkit for the acquisition and analysis of a wide variety of imaging data by integrating the ease of use of various programming environments such as LABVIEW, IGOR PRO, MATLAB, SCILAB, and others. This toolkit is designed to allow the user to quickly program a variety of standard microscopy components for custom microscopy applications allowing much more flexibility than other packages. Included are both programming tools as well as graphical user interface classes allowing a standard, consistent, and easy to maintain scripting environment. This programming toolkit allows easy access to most commonly used cameras, stages, and shutters through the Micromanager project so the scripter can focus on their custom application instead of boilerplate code generation.

  6. Community College Guide for Associate Degree Programs in Auto and Truck Service/Management.

    Science.gov (United States)

    Automobile Manufacturers-American Vocational Association Industry Planning Council.

    Realizing that the community college serves in a special capacity through the development of varied and flexible curriculms, this program guide was developed by the Automobile Manufacturers-American Vocational Association Industry Planning Council. For the benefit of administrators and curriculum specialists, it gives a setting for associate…

  7. Productive High Performance Parallel Programming with Auto-tuned Domain-Specific Embedded Languages

    Science.gov (United States)

    2013-01-02

    http://dl.acm. org/citation.cfm?id=645980.674267. [93] Inc. PLT Scheme. The Racket Language. 2012. URL: http://racket-lang.org. [94] Sebastian Pop...URL: http://pypi.python.org/pypi. [100] Python Programming Language - Offical Website. 2012. URL: http://www.python.org. [101] Gabriel Rivera and Chau

  8. AutoCAD platform customization user interface, AutoLISP, VBA, and beyond

    CERN Document Server

    Ambrosius, Lee

    2015-01-01

    Take control of AutoCAD to boost the speed, quality, and precision of your work Senior drafters and savvy users are increasingly taking AutoCAD customization out of the hands of system administrators, and taking control of their own workflow. In AutoCAD Platform Customization, Autodesk customization guru Lee Ambrosius walks you through a multitude of customization options using detailed tutorials and real-world examples applicable to AutoCAD, AutoCAD LT, Civil 3D, Plant 3D, and other programs built on the AutoCAD platform. By unleashing the full power of the software, you'll simplify and str

  9. 40 CFR Table 1 to Subpart B of... - Volatile Organic Compound (VOC) Content Limits for Automobile Refinish Coatings

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Volatile Organic Compound (VOC) Content... Compound (VOC) Content Limits for Automobile Refinish Coatings Coating category Grams VOC per liter Pounds VOC per gallon a Pretreatment wash primers 780 6.5 Primers/primer surfacers 580 4.8 Primer sealers 550...

  10. AutoCAD 2008 and AutoCAD LT 2008 Bible

    CERN Document Server

    Finkelstein, Ellen

    2011-01-01

    "Whether you're new to AutoCAD or a veteran, you will undoubtedly find this book to be an excellent resource."-- Abhi Singh, AutoCAD Product Manager, Autodesk, Inc.Here's the book that makes AutoCAD approachableEven the people at Autodesk look to Ellen Finkelstein for AutoCAD training, so who better to teach you about AutoCAD 2008? This comprehensive guide brings veterans up to speed on AutoCAD updates and takes novices from the basics to programming in AutoLISP(r) and VBA. Every feature is covered in a logical order, and with the Quick Start chapter, you'll be creating drawings on your very f

  11. Instant AutoIt scripting

    CERN Document Server

    Laso, Emilio Aristides de Fez

    2013-01-01

    Filled with practical, step-by-step instructions and clear explanations for the most important and useful tasks. This is a Packt Instant How-to guide, which provides concise and clear recipes for getting started with AutoIt.Instant AutoIt Scripting Essentials How-to is for beginners who wish to know more about automation and programming, system administration developers who intent to automate/manage clusters and servers, and for computer programmers who want to control any PC to create seamless automation apps.

  12. Development of an AutoFlat program for the acquisition of effective flat images in the automated observation system

    Directory of Open Access Journals (Sweden)

    Joh-Na Yoon

    2013-12-01

    Full Text Available The purpose of this study is to develop an observation program for obtaining effective flat images that are necessary for photometric observation. The development of the program was achieved by improving the existing method for obtaining twilight flat images. The existing method for obtaining twilight flat images acquires flat images by observing the sky light after sunset or light before sunrise. The decision of when to observe flat images at each night is solely dependent on the judgment of an observer, and thus the obtained flat images for particular nights may not be clean. Especially, in the case of the observatories where an automated observation system is in operation, there is a difficulty that an observer should pay attention during sunrise and sunset in order to obtain flat images. In this study, a computer program is developed to improve this inconvenience and to efficiently perform photometric observation in the observatories where an automated observation system is applied. This program can obtain flat images by calculating the time for obtaining flat images automatically and the exposure time using a numerically calculated function. When obtaining twilight flat images at dusk and at dawn, the developed program performs automated observation and provides effective flat images by acquiring appropriate exposure time considering the sunrise and sunset times that vary depending on the day of observation. The code for performing this task was added to Obs Tool II (Yoon et al. 2006, which is the automated observation system of the Chungbuk National University Observatory, and the usefulness of the developed program was examined by performing an actual automated observation. If this program is applied to other observatories where automated observation is in operation, it is expected that stable and highquality flat images could be obtained, which can be used for the pre-processing of photometric observation data.

  13. Auto Mechanics. Heavy Equipment. Small Engines.

    Science.gov (United States)

    Finnerty, Kathy

    Developed for use in auto mechanics, Heavy Equipment Repair and Operation (HERO), and small engines programs, these study guides and supplemental worksheets cover operating principles, lubrication, cooling system, ignition circuit and electrical system, and fuel system. The worksheets and guide questions are phrased to emphasize key points…

  14. AutoCAD

    DEFF Research Database (Denmark)

    Jensen, Henrik

    1998-01-01

    I 1998 var AutoCAD Arkitektskolens basale CAD-tilbud til de studerende. Kursets vægt ligger på konstruktion og strukturering af 3d-modeller og med udgangspunkt i dette, 2d-tegning. Kurset er opbygget over CAD Clasic skabelonen (se min forskning). Kompendiet kan bruges til selvstudium....

  15. The Durban Auto Cluster

    DEFF Research Database (Denmark)

    Lorentzen, Jochen; Robbins, Glen; Barnes, Justin

    2004-01-01

    The paper describes the formation of the Durban Auto Cluster in the context of trade liberalization. It argues that the improvement of operational competitiveness of firms in the cluster is prominently due to joint action. It tests this proposition by comparing the gains from cluster activities...

  16. AUTO-EXPANSIVE FLOW

    Science.gov (United States)

    Physics suggests that the interplay of momentum, continuity, and geometry in outward radial flow must produce density and concomitant pressure reductions. In other words, this flow is intrinsically auto-expansive. It has been proposed that this process is the key to understanding...

  17. Beginning AutoCAD 2002

    CERN Document Server

    McFarlane, Bob

    2002-01-01

    New features in AutoCAD 2002 are covered in this book, making it a useful refresher course for anyone using AutoCAD at this level, and upgrading to the new software release. The material in the book is also relevant to anyone using other recent releases, including, AutoCAD 2000.

  18. AutoCAD 2014 and AutoCAD LT 2014

    CERN Document Server

    Gladfelter, Donnie

    2013-01-01

    A step-by-step tutorial introduction to AutoCAD As the only book to teach AutoCAD using a continuous tutorial which allows you to follow along sequentially or jump in at any exercise by downloading the drawing files, this Autodesk Official Press book is ideal for the AutoCAD novice. Industry expert and AutoCAD guru Donnie Gladfelter walks you through the powerful features of AutoCAD, provides you with a solid foundation of the basics, and shares the latest industry standards and techniques. The hands-on tutorial project inspired by real-world workflows that runs throughout the book

  19. MS AutoCad

    DEFF Research Database (Denmark)

    Andersen, Michael Rye; Heinicke, Hugo

    1996-01-01

    Formålet med dette notat er at give en introduktion til tegning af et generalarrangement ved anvendelse af CAD-programmet AutoCAD. Generalarrangementets formål er at skabe en overskuelig præsentation af et skibsprojekt. Det skal gøres indenfor de rammer, som ligger til grund for praktiskprojekter......Formålet med dette notat er at give en introduktion til tegning af et generalarrangement ved anvendelse af CAD-programmet AutoCAD. Generalarrangementets formål er at skabe en overskuelig præsentation af et skibsprojekt. Det skal gøres indenfor de rammer, som ligger til grund...

  20. PERFORMING [AUTO] ETHNOGRAPHY POLITICALLY

    OpenAIRE

    Denzin, Norman K.

    2015-01-01

    Building on earlier arguments, I propose a civic, publicly responsable [auto] ethnography that addresses the central issues of self, race, gender, class, society, and democracy.  I begin with pedagogies of hope and the sociological and ethnographic imaginations.  I turn then to the ethnographer and cultural studies, reviewing several models of critical ethnography. I next examine critical performance pedagogy, politics, and critical race theory, and conclude with a brief discussion of the pra...

  1. Myocarditis in auto-immune or auto-inflammatory diseases.

    Science.gov (United States)

    Comarmond, Cloé; Cacoub, Patrice

    2017-08-01

    Myocarditis is a major cause of heart disease in young patients and a common precursor of heart failure due to dilated cardiomyopathy. Some auto-immune and/or auto-inflammatory diseases may be accompanied by myocarditis, such as sarcoidosis, Behçet's disease, eosinophilic granulomatosis with polyangiitis, myositis, and systemic lupus erythematosus. However, data concerning myocarditis in such auto-immune and/or auto-inflammatory diseases are sparse. New therapeutic strategies should better target the modulation of the immune system, depending on the phase of the disease and the type of underlying auto-immune and/or auto-inflammatory disease. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Methylene chloride intoxication in a furniture refinisher. A comparison of exposure estimates utilizing workplace air sampling and blood carboxyhemoglobin measurements.

    Science.gov (United States)

    Shusterman, D; Quinlan, P; Lowengart, R; Cone, J

    1990-05-01

    A 35-year-old furniture refinisher came to the occupational medicine clinic with complaints of upper respiratory irritation, fatigue, and lightheadedness occurring on a daily basis after using a methylene chloride-containing paint stripper. Determinations of blood carboxyhemoglobin (COHb) on three occasions showed an apparently linear elevation of COHb as a function of hours worked on the day of sampling. COHb levels predicted from spot industrial hygiene measurements were in close concordance with those observed in the patient, indicating the potential usefulness of COHb monitoring in estimating airborne exposure levels. Methylene chloride (or dichloromethane) is an organic solvent that has found wide use as a degreaser, paint remover, aerosol propellant, and a blowing agent for polyurethane foams, and as a solvent in food processing, photographic film production, and plastics manufacturing. Discovery of its unusual metabolic fate--conversion to carbon monoxide in vivo--has earned the compound a special place in the solvent toxicology literature. Demonstration of oncogenicity in experimental animals has occasioned a reconsideration of exposure limits, with emphasis upon stricter controls. In some workplaces, conditions prevail in which controls are inadequate to prevent even acute toxicity, much less long-term exposure risks.

  3. Apparatus-Program Complexes Processing and Creation of Essentially non-Format Documents on the Basis of Technology Auto-Adaptive Fonts

    Directory of Open Access Journals (Sweden)

    E. G. Andrianova

    2014-01-01

    Full Text Available The need to translate paper documents into electronic form demanded a development of methods and algorithms for automatic processing systems and web publishing unformatted graphic documents of on-line libraries. Translation of scanned images into modern formats of electronic documents using OCR programmes faces serious difficulties. These difficulties are connected with the standardization set of fonts and design of printed documents. There is also a need to maintain the original form of electronic format of such documents. The article discusses the possibility for building an extensible adaptive dictionary of graphic objects, which constitute unformatted graphics documents. Dictionary automatically adjusted as graphics processing and accumulation of statistical information for each new document. This adaptive extensible dictionary of graphic letters, fonts, and other objects of automated particular document processing is called "auto-adaptive font", and a set of its application methods is named "auto-adaptive font technology."Based on the theory of estimation algorithms, a mathematical model is designed. It allows us to represent all objects of unformatted graphic document in a unified manner to build a feature vector for each object, and evaluate a similarity of these objects in the selected metric. The algorithm of the adaptive models of graphic images is developed and a criterion for combining similar properties in one element to build an auto-adaptive font is offered thus allowing us to build a software core of hardware-software complex for processing the unformatted graphic documents. A standard block diagram of hardware-software complex is developed to process the unformatted graphic documents. The article presents a description of all the blocks of this complex, including document processing station and its interaction with the web server of publishing electronic documents.

  4. PERFORMING [AUTO] ETHNOGRAPHY POLITICALLY

    Directory of Open Access Journals (Sweden)

    Norman K. Denzin

    2015-06-01

    Full Text Available Building on earlier arguments, I propose a civic, publicly responsable [auto] ethnography that addresses the central issues of self, race, gender, class, society, and democracy.  I begin with pedagogies of hope and the sociological and ethnographic imaginations.  I turn then to the ethnographer and cultural studies, reviewing several models of critical ethnography. I next examine critical performance pedagogy, politics, and critical race theory, and conclude with a brief discussion of the practices of a performative cultural politics.

  5. Promoção do autoconceito e auto estima através de um programa de leitura a par Promoting self-concept and self esteem through a peer reading program

    Directory of Open Access Journals (Sweden)

    Vera Monteiro

    2012-01-01

    Full Text Available Um autoconceito positivo é fundamental para o sucesso académico das crianças. Uma forma de promover o autoconceito é implementando programas tutoriais. Deste modo, esta investigação teve como objectivo implementar e avaliar os efeitos de um Programa de Leitura a Par, no autoconceito de alunos dos 2º e 4º anos de escolaridade e na auto-estima dos alunos mais velhos. Para avaliar as autopercepções utilizaram-se duas escalas devido à discrepância de idade das crianças. Os resultados obtidos demonstram que este Programa teve um efeito positivo em todas as dimensões do autoconceito, quer para os tutores como para os tutorandos, e na auto-estima dos tutores. As crianças do Grupo Experimental apresentaram valores estatisticamente superiores aos dos alunos do Grupo de Controle.A positive self-concept is essential for children's academic success. One way of promoting self-concept is by the implementation of tutorial programs. Thus, this research aimed to evaluate the effects of a Peer Reading Program on self-concept of 2nd and 4th grade students and on self-esteem of older students. In order to assess self-perceptions two scales were used due to the discrepancy in children's age. The results show that the Peer Reading Program had a positive effect on all dimensions of self-concept, for tutors and tutees, and on tutors' self-esteem. Children's outcomes obtained in the experimental group were statistically higher than those of students in the control group.

  6. Auto-fotografi som metode

    DEFF Research Database (Denmark)

    Mogensen, Mette

    2014-01-01

    Artiklen sætter fokus på auto-fotografi som metode i arbejdsmiljøforskningen. Den organisationsæstetiske tilgang, som metoden ofte forbindes med, udfordres med afsæt i en performativ og aktørnetværks-teoretisk position. Gennem en analyse af et enkelt auto-fotografi vises hvordan en artikulation af...

  7. Pharmacist Prescriptive Authority for Epinephrine Auto-Injectors in Idaho

    Directory of Open Access Journals (Sweden)

    Alex J Adams, PharmD, MPH

    2016-10-01

    Full Text Available Objective: To describe recent legislation in Idaho that granted pharmacists autonomous prescriptive authority for epinephrine auto-injectors. Practice Innovation: States have taken action to increase access to epinephrine auto-injectors by allowing them to be stocked and prepositioned at locations where individuals may encounter allergens. All 50 states have allowed schools to maintain stock supplies of epinephrine auto-injectors and 26 states have allowed other entities, such as summer camps, daycare centers, gymnasiums, and restaurants to begin stocking product as well. In 2016, legislation in Idaho pursued entity stocking while simultaneously granting pharmacists autonomous prescriptive authority for epinephrine auto-injectors. Results: Idaho legislation granted prescriptive authority for pharmacists for epinephrine auto-injectors not just for individual patients, but also for authorized entities. No collaborative practice agreement is necessary. To receive an epinephrine auto-injector, an agent or employee of an authorized entity must present proof that they have completed an appropriate training program. Pharmacists are provided liability protections when prescribing in good faith to an authorized entity. Conclusion: Idaho’s legislation provides a potential model for pharmacist prescriptive authority for epinephrine auto-injectors that other states may consider pursuing in the years ahead.   Type: Commentary

  8. AutoCAD 2014 essentials

    CERN Document Server

    Onstott, Scott

    2013-01-01

    Learn crucial AutoCAD tools and techniques with this Autodesk Official Press Book Quickly become productive using AutoCAD 2014 and AutoCAD LT 2014 with this full color Autodesk Official Press guide. This unique learning resource features concise, straightforward explanations and real-world, hands-on exercises and tutorials. Following a quick discussion of concepts and goals, each chapter moves on to an approachable hands-on exercise designed to reinforce real-world tactics and techniques. Compelling, full-color screenshots illustrate tutorial steps, and chapters conclude with relat

  9. Sajandi Auto / Willem J. Staat

    Index Scriptorium Estoniae

    Staat, Willem J.

    1998-01-01

    Näitus 'Car of the Century' toimus 27. juunist 5. juulini Amsterdamis, 21. augustist 7. septembrini Torontos. Edasi liigub näitus Pariisi, Melbourne'i ja Lissaboni. Võistluse korraldusest. Lõplikult selgitatakse Sajandi Auto 4. detsembril 1999.

  10. Esma Auto ja Mazda on loodud kestma

    Index Scriptorium Estoniae

    2003-01-01

    Ülevaade olulisematest sündmustest Esma Auto kümne tegevusaasta jooksul. Kommenteerivad Tarmo Järvoja, Mart Laar ja Enn Sau. Diagrammid ja skeemid: AS Esma Auto müügi statistika läbi aastate; AS Esma Auto kasum ja klientide arv aastate lõikes; Esma Auto esindused Eestis ja pakutavad teenused

  11. An alternative approach for assessment of liquid chromatography-mass spectrometry matrix effects using auto-sampler programmed co-injection.

    Science.gov (United States)

    Rogers, Caitlyn A; Stockham, Peter C; Nash, Christine M; Martin, Sheridan M; Kostakis, Chris; Lenehan, Claire E

    2016-03-01

    We report the use of auto-sampler programmable functions to co-inject analyte standard solution and matrix extract to assess ion enhancement and suppression (matrix effects) in LC-MS. This is effectively an automated post-extraction addition (APEA) procedure, emulating the manual post-extraction addition (PEA) approach widely adopted for assessment of matrix effects. To verify that APEA was comparable to the conventional PEA approach, matrix effects were determined using both methods for a selection of 31 illicit and pharmaceutical drugs in 10 different human urine extracts. Matrix effects measured using APEA were statistically indistinguishable from manual PEA methodology for 27 of the 31 drugs. Of the four drugs that showed significant differences using the two methods, three differed by less than 2 %, which is within the expected accuracy limits required for matrix effect determinations. The remaining analyte, trimeprazine, was found to degrade in the spiked PEA matrix extract, accounting for the difference between matrix effects measured by the PEA and APEA approaches. APEA enables a single matrix extract to be assessed at multiple analyte concentrations, resulting in a considerable reduction in sample preparation time. In addition, APEA can reduce the quantity of analyte-free sample matrix required for matrix effect assessment, which is an important consideration in certain analytical and bioanalytical fields. This work shows that APEA may be considered as an acceptable alternative to PEA for the assessment of matrix effects in LC-MS method validation and may be applicable to a variety of matrices such as environmental samples.

  12. AutoCAD 2015 and AutoCAD LT 2015

    CERN Document Server

    Gladfelter, Donnie

    2014-01-01

    Learn AutoCAD by example with this tutorial-based guide from Autodesk Official Press Whether you are just starting out or an experienced user wanting to brush up on your skills, this Autodesk Official Press book provides you with concise explanations, focused examples, and step-by-step instructions through a hands-on tutorial project that runs throughout the book. As you progress through the project, the book introduces you to the Microsoft Windows-based AutoCAD interface and then guides you through basic commands and creating drawings. A downloadable file is available from the website so that

  13. Fra form-Z til AutoCad

    DEFF Research Database (Denmark)

    Jensen, Henrik

    2003-01-01

    Dette kursus er lavet for at forberede de studerende til deres tegnestuepraktik, og dets indhold er planlagt i samarbejde med tegnestuerne. I 2003 var form-Z Arkitektskolens grundlæggende CAD-program; men på tegnestuerne arbejde man med AutoCad. Kurset er opbygget over CAD Clasic skabelonen (se min...

  14. Instant Autodesk AutoCAD 2014 customization with .NET

    CERN Document Server

    Nelson, Tom

    2013-01-01

    Filled with practical, step-by-step instructions and clear explanations for the most important and useful tasks. An instruction-based guide with examples written in the C# programming language. VB.NET programmers can also take advantage of these examples by using one of the free conversion websites to convert the examples to VB.NET.Clear, step-by-step instructions and complete code examples illustrate the processes, making it easy to develop your own custom AutoCAD tools.This book is perfect if you are interested in customizing AutoCAD 2014 using the .NET API. You should have a basic familiari

  15. Investigating the Simulink Auto-Coding Process

    Science.gov (United States)

    Gualdoni, Matthew J.

    2016-01-01

    Model based program design is the most clear and direct way to develop algorithms and programs for interfacing with hardware. While coding "by hand" results in a more tailored product, the ever-growing size and complexity of modern-day applications can cause the project work load to quickly become unreasonable for one programmer. This has generally been addressed by splitting the product into separate modules to allow multiple developers to work in parallel on the same project, however this introduces new potentials for errors in the process. The fluidity, reliability and robustness of the code relies on the abilities of the programmers to communicate their methods to one another; furthermore, multiple programmers invites multiple potentially differing coding styles into the same product, which can cause a loss of readability or even module incompatibility. Fortunately, Mathworks has implemented an auto-coding feature that allows programmers to design their algorithms through the use of models and diagrams in the graphical programming environment Simulink, allowing the designer to visually determine what the hardware is to do. From here, the auto-coding feature handles converting the project into another programming language. This type of approach allows the designer to clearly see how the software will be directing the hardware without the need to try and interpret large amounts of code. In addition, it speeds up the programming process, minimizing the amount of man-hours spent on a single project, thus reducing the chance of human error as well as project turnover time. One such project that has benefited from the auto-coding procedure is Ramses, a portion of the GNC flight software on-board Orion that has been implemented primarily in Simulink. Currently, however, auto-coding Ramses into C++ requires 5 hours of code generation time. This causes issues if the tool ever needs to be debugged, as this code generation will need to occur with each edit to any part of

  16. Auto-Generated Semantic Processing Services

    Science.gov (United States)

    Davis, Rodney; Hupf, Greg

    2009-01-01

    Auto-Generated Semantic Processing (AGSP) Services is a suite of software tools for automated generation of other computer programs, denoted cross-platform semantic adapters, that support interoperability of computer-based communication systems that utilize a variety of both new and legacy communication software running in a variety of operating- system/computer-hardware combinations. AGSP has numerous potential uses in military, space-exploration, and other government applications as well as in commercial telecommunications. The cross-platform semantic adapters take advantage of common features of computer- based communication systems to enforce semantics, messaging protocols, and standards of processing of streams of binary data to ensure integrity of data and consistency of meaning among interoperating systems. The auto-generation aspect of AGSP Services reduces development time and effort by emphasizing specification and minimizing implementation: In effect, the design, building, and debugging of software for effecting conversions among complex communication protocols, custom device mappings, and unique data-manipulation algorithms is replaced with metadata specifications that map to an abstract platform-independent communications model. AGSP Services is modular and has been shown to be easily integrable into new and legacy NASA flight and ground communication systems.

  17. AutoCAD 2008 for dummies

    CERN Document Server

    Byrnes, David

    2007-01-01

    A gentle, humorous introduction to this fearsomely complex software that helps new users start creating 2D and 3D technical drawings right awayCovers the new features and enhancements in the latest AutoCAD version and provides coverage of AutoCAD LT, AutoCAD''s lower-cost siblingTopics covered include creating a basic layout, using AutoCAD DesignCenter, drawing and editing, working with dimensions, plotting, using blocks, adding text to drawings, and drawing on the InternetAutoCAD is the leading CAD software for architects, engineers, and draftspeople who need to create detailed 2D and 3D tech

  18. AutoCAD 2014 for dummies

    CERN Document Server

    Fane, Bill

    2013-01-01

    Find your way around AutoCAD 2014 with this full-color, For Dummies guide!Put away that pencil and paper and start putting the power of AutoCAD 2014 to work in your CAD projects and designs. From setting up your drawing environment to using text, dimensions, hatching, and more, this guide walks you through AutoCAD basics and provides you with a solid understanding of the latest CAD tools and techniques. You'll also benefit from the full-color illustrations that mirror exactly what you'll see on your AutoCAD 2014 screen and highlight the importance of AutoCAD's Mode

  19. [Stress and auto-immunity].

    Science.gov (United States)

    Delévaux, I; Chamoux, A; Aumaître, O

    2013-08-01

    The etiology of auto-immune disorders is multifactorial. Stress is probably a participating factor. Indeed, a high proportion of patients with auto-immune diseases report uncommon stress before disease onset or disease flare. The biological consequences of stress are increasingly well understood. Glucocorticoids and catecholamines released by hypothalamic-pituitary-adrenal axis during stress will alter the balance Th1/Th2 and the balance Th17/Treg. Stress impairs cellular immunity, decreases immune tolerance and stimulates humoral immunity exposing individuals to autoimmune disease among others. The treatment for autoimmune disease should include stress management. Copyright © 2012 Société nationale française de médecine interne (SNFMI). Published by Elsevier SAS. All rights reserved.

  20. Self-Programmed Counseling and Self-Programmed Control Manual. A Guide to Self-Image Development with Emphasis on the Chicano Student. Student's Guide = Manual de Sistema de Consejo Auto Programado y Control Auto Programado. Una Guia Para el Desarrollo de La Imagen Propia Con un Enfasis en el Estudiante Chicano.

    Science.gov (United States)

    Mireles, S. Raymond

    Self-Programmed Counseling, the instructor's guidance, and Self-Programmed Control (SPC), the student's response, was initially developed by Title III Project USTED (United Students and Teachers for Educational Development) for Mexican American college students on academic probation to use on a non-credit, special group counseling basis. As part…

  1. Combinatorial Gene Regulation Using Auto-Regulation

    Science.gov (United States)

    Hermsen, Rutger; Ursem, Bas; ten Wolde, Pieter Rein

    2010-01-01

    As many as 59% of the transcription factors in Escherichia coli regulate the transcription rate of their own genes. This suggests that auto-regulation has one or more important functions. Here, one possible function is studied. Often the transcription rate of an auto-regulator is also controlled by additional transcription factors. In these cases, the way the expression of the auto-regulator responds to changes in the concentrations of the “input” regulators (the response function) is obviously affected by the auto-regulation. We suggest that, conversely, auto-regulation may be used to optimize this response function. To test this hypothesis, we use an evolutionary algorithm and a chemical–physical model of transcription regulation to design model cis-regulatory constructs with predefined response functions. In these simulations, auto-regulation can evolve if this provides a functional benefit. When selecting for a series of elementary response functions—Boolean logic gates and linear responses—the cis-regulatory regions resulting from the simulations indeed often exploit auto-regulation. Surprisingly, the resulting constructs use auto-activation rather than auto-repression. Several design principles show up repeatedly in the simulation results. They demonstrate how auto-activation can be used to generate sharp, switch-like activation and repression circuits and how linearly decreasing response functions can be obtained. Auto-repression, on the other hand, resulted only when a high response speed or a suppression of intrinsic noise was also selected for. The results suggest that, while auto-repression may primarily be valuable to improve the dynamical properties of regulatory circuits, auto-activation is likely to evolve even when selection acts on the shape of response function only. PMID:20548950

  2. Business Plan : Green Auto Spa

    OpenAIRE

    Sherpa, Nyima

    2017-01-01

    Business plan is an important blue print tool that helps entrepreneurs and business managers to think through their business idea, convince possible investors and ensure financial success to the business. A good business plan outlines company’s product, how the production will take place and how the product or service is going to ensure that it reaches its’ targeted market. The purpose of this project is to create a business plan for a new and soon-to-be established auto wash shop with s...

  3. AutoClickChem: click chemistry in silico.

    Science.gov (United States)

    Durrant, Jacob D; McCammon, J Andrew

    2012-01-01

    Academic researchers and many in industry often lack the financial resources available to scientists working in "big pharma." High costs include those associated with high-throughput screening and chemical synthesis. In order to address these challenges, many researchers have in part turned to alternate methodologies. Virtual screening, for example, often substitutes for high-throughput screening, and click chemistry ensures that chemical synthesis is fast, cheap, and comparatively easy. Though both in silico screening and click chemistry seek to make drug discovery more feasible, it is not yet routine to couple these two methodologies. We here present a novel computer algorithm, called AutoClickChem, capable of performing many click-chemistry reactions in silico. AutoClickChem can be used to produce large combinatorial libraries of compound models for use in virtual screens. As the compounds of these libraries are constructed according to the reactions of click chemistry, they can be easily synthesized for subsequent testing in biochemical assays. Additionally, in silico modeling of click-chemistry products may prove useful in rational drug design and drug optimization. AutoClickChem is based on the pymolecule toolbox, a framework that may facilitate the development of future python-based programs that require the manipulation of molecular models. Both the pymolecule toolbox and AutoClickChem are released under the GNU General Public License version 3 and are available for download from http://autoclickchem.ucsd.edu.

  4. AutoClickChem: click chemistry in silico.

    Directory of Open Access Journals (Sweden)

    Jacob D Durrant

    Full Text Available Academic researchers and many in industry often lack the financial resources available to scientists working in "big pharma." High costs include those associated with high-throughput screening and chemical synthesis. In order to address these challenges, many researchers have in part turned to alternate methodologies. Virtual screening, for example, often substitutes for high-throughput screening, and click chemistry ensures that chemical synthesis is fast, cheap, and comparatively easy. Though both in silico screening and click chemistry seek to make drug discovery more feasible, it is not yet routine to couple these two methodologies. We here present a novel computer algorithm, called AutoClickChem, capable of performing many click-chemistry reactions in silico. AutoClickChem can be used to produce large combinatorial libraries of compound models for use in virtual screens. As the compounds of these libraries are constructed according to the reactions of click chemistry, they can be easily synthesized for subsequent testing in biochemical assays. Additionally, in silico modeling of click-chemistry products may prove useful in rational drug design and drug optimization. AutoClickChem is based on the pymolecule toolbox, a framework that may facilitate the development of future python-based programs that require the manipulation of molecular models. Both the pymolecule toolbox and AutoClickChem are released under the GNU General Public License version 3 and are available for download from http://autoclickchem.ucsd.edu.

  5. AutoCTF: Creating Diverse Pwnables via Automated Bug Injection

    Science.gov (United States)

    2017-05-31

    tech- niques to create AutoCTF, a week-long event involving teams from four universities. For evaluation, we con- ducted surveys and semi- structured ...injected code at the attack point to reference this array instead of calling lava_get. This approach eliminates the need for a global data structure ...in the filesys- tem . This program is 239 lines of source code as mea- sured by David Wheeler’s sloccount. The second service, fifth, is an

  6. Self-Image Development: A Chicano Enfasis. Self-Programmed Counseling and Self-Programmed Control. Instructor's Guide = Desarrollo de la Imagen Propia: Enfasis en el Chicano. Sistema de Consejo y Control Auto-Programado. Manuel del Profesor.

    Science.gov (United States)

    Mireles, S. Raymond

    Self-Programmed Counseling, the instructor's guidance, and Self-Programmed Control (SPC), the student's response, was initially developed by Title III Project USTED (United Students and Teachers for Educational Development) for Mexican American students on academic probation to use on a non-credit, special group counseling basis. As part of a…

  7. AutoCAD 2015 and AutoCAD LT 2015 bible

    CERN Document Server

    Finkelstein, Ellen

    2014-01-01

    The perfect reference for all AutoCAD users AutoCAD 2015 and AutoCAD LT 2015 Bible is the book you want to have close at hand to answer those day-to-day questions about this industry-leading software. Author and Autodesk University instructor Ellen Finkelstein guides readers through AutoCAD 2015 and AutoCAD LT 2015 with clear, easy-to-understand instruction and hands-on tutorials that allow even total beginners to create a design on their very first day. Although simple and fundamental enough to be used by those new to CAD, the book is so comprehensive that even Autodesk power u

  8. Query auto completion in information retrieval

    NARCIS (Netherlands)

    Cai, Fei

    2016-01-01

    Query auto completion is an important feature embedded into today's search engines. It can help users formulate queries which other people have searched for when he/she finishes typing the query prefix. Today's most sophisticated query auto completion approaches are based on the collected query logs

  9. Analysis on the workspace of palletizing robot based on AutoCAD

    Science.gov (United States)

    Li, Jin-quan; Zhang, Rui; Guan, Qi; Cui, Fang; Chen, Kuan

    2017-10-01

    In this paper, a four-degree-of-freedom articulated palletizing robot is used as the object of research. Based on the analysis of the overall configuration of the robot, the kinematic mathematical model is established by D-H method to figure out the workspace of the robot. In order to meet the needs of design and analysis, using AutoCAD secondary development technology and AutoLisp language to develop AutoCAD-based 2D and 3D workspace simulation interface program of palletizing robot. At last, using AutoCAD plugin, the influence of structural parameters on the shape and position of the working space is analyzed when the structure parameters of the robot are changed separately. This study laid the foundation for the design, control and planning of palletizing robots.

  10. Second auto-SCT for treatment of relapsed multiple myeloma.

    Science.gov (United States)

    Gonsalves, W I; Gertz, M A; Lacy, M Q; Dispenzieri, A; Hayman, S R; Buadi, F K; Dingli, D; Hogan, W J; Kumar, S K

    2013-04-01

    High-dose therapy and auto-SCT remain integral in the initial treatment of multiple myeloma (MM), and are increasingly being applied for management of relapsed disease. We examined the outcomes in 98 patients undergoing salvage auto-SCT (auto-SCT2) for relapsed MM after receiving an initial transplant (auto-SCT1) between 1994 and 2009. The median age at auto-SCT2 was 60 years (range: 35-74). The median time between auto-SCT1 and auto-SCT2 was 46 months (range: 10-130). Treatment-related mortality was seen in 4%. The median PFS from auto-SCT2 was 10.3 (95% confidence interval (CI): 7-14) months and the median OS from auto-SCT2 was 33 months (95% CI: 28-51). In a multivariable analysis, shorter time to progression (TTP) after auto-SCT1, not achieving a CR after auto-SCT2, higher number of treatment regimens before auto-SCT2 and a higher plasma cell labeling index at auto-SCT2 predicted for shorter PFS. However, only a shorter TTP after auto-SCT1 predicted for a shorter OS post auto-SCT2. Hence, auto-SCT2 is an effective and feasible therapeutic option for MM patients relapsing after other treatments, especially in patients who had a TTP of at least 12 months after their auto-SCT1.

  11. Auto-incompatibilidade em plantas

    Directory of Open Access Journals (Sweden)

    Schifino-Wittmann Maria Teresa

    2002-01-01

    Full Text Available A auto-incompatibilidade (AI é a incapacidade de uma planta fértil formar sementes quando fertilizada por seu próprio pólen. É um mecanismo fisiólogico, com base genética, que promove a alogamia, e tem despertado a atenção de geneticistas e melhoristas de plantas. Atualmente, a ênfase nas pesquisas está na identificação e entendimento dos processos moleculares e celulares que levam ao reconhecimento e à rejeição do pólen auto-incompatível, incluindo a identificação, localização e seqüenciamento das proteínas, enzimas e genes envolvidos. Existem dois tipos principais de AI, a gametofítica (AIG, em que a especificidade do pólén é gerada pelo alelo S do genoma haplóide do grão do pólen (gametófito, e a esporofítica (AIE, em que a especificidade é gerada pelo genótipo diplóide da planta adulta (esporófito que deu origem ao grão de pólen. A AIE pode ser homomórfica, quando não existem modificações florais que acompanham o processo, ou heteromórfica, quando, com o processo de AI, ocorrem modificações florais. A reação da AI engloba desde o impedimento da germinação do pólen até o rompimento do tubo polínico. A ocorrência de AI em espécies de interesse econômico pode ter uma importância muito grande, sendo muito positiva em alguns casos e um empecilho em outros, dependendo da parte da planta (vegetativa ou reprodutiva que é colhida e do tipo de reprodução, sexual ou vegetativa. A utilização da AI no melhoramento de plantas é feita há bastante tempo, mas existe uma lacuna entre o grau de detalhamento do conhecimento teórico, como as bases genética e molecular, e a aplicação deste conhecimento no melhoramento.

  12. Programe sua mente e seja bem sucedido, feliz, influente, próspero e saudável : um estudo da persuasão em livros de auto-ajuda

    OpenAIRE

    Lilian Salete Alonso Moreira Lima

    2005-01-01

    O objetivo principal desta dissertação é analisar de que forma se apresenta a persuasão em livros de auto-ajuda. O corpus constitui-se dos livros Como fazer amigos e influenciar pessoas, de Dale Carnegie; Você pode curar sua vida, de Louise L. Hay; A carícia essencial e O sucesso é ser feliz, de Roberto Shinyashiki; O sucesso não ocorre por acaso, Comunicação global e Prosperidade, de Lair Ribeiro; As sete leis espirituais do sucesso, de Deepak Chopra. A persuasão é utilizada, neste trabalho,...

  13. The Auto-Gopher Deep Drill

    Science.gov (United States)

    Badescu, Mircea

    2014-01-01

    Subsurface penetration by coring, drilling or abrading is of great importance for a large number of space and earth applications. An Ultrasonic/Sonic Drill/Corer (USDC) has been in development at JPL's Nondestructive Evaluation and Advanced Actuators (NDEAA) lab as an adaptable tool for many of these applications. The USDC uses a novel drive mechanism to transform the high frequency ultrasonic or sonic vibrations of the tip of a horn into a lower frequency sonic hammering of a drill bit through an intermediate free-flying mass. The USDC device idea has been implemented at various scales from handheld drills to large diameter coring devices. A series of computer programs that model the function and performance of the USDC device were developed and were later integrated into an automated modeling package. The USDC has also evolved from a purely hammering drill to a rotary hammer drill as the design requirements increased form small diameter shallow drilling to large diameter deep coring. A synthesis of the Auto-Gopher development is presented in this paper.

  14. Trends in auto emissions and gasoline composition.

    Science.gov (United States)

    Sawyer, R F

    1993-12-01

    The invention of the spark-ignited internal combustion engine provided a market for a petroleum middle distillate, gasoline, about 100 years ago. The internal combustion engine and gasoline have co-evolved until motor vehicles now annually consume about 110 billion gallons of gasoline in the United States. Continuing air pollution problems and resulting regulatory pressures are driving the need for further automotive emissions reductions. Engine and emissions control technology provided most earlier reductions. Changing the composition of gasoline will play a major role in the next round of reductions. The engineering and regulatory definition of a reformulated gasoline is proceeding rapidly, largely as the result of an auto and oil industry cooperative data generation program. It is likely that this new, reformulated gasoline will be introduced in high-ozone regions of the United States in the mid-1990s. Alternative clean fuels, primarily methane, methanol, and liquid petroleum gas, will become more widely used during this same period, probably first in fleet operations.

  15. MICRO AUTO GASIFICATION SYSTEM: EMISSIONS ...

    Science.gov (United States)

    A compact, CONEX-housed waste to energy unit, Micro Auto Gasification System (MAGS), was characterized for air emissions from burning of military waste types. The MAGS unit is a dual chamber gasifier with a secondary diesel-fired combustor. Eight tests were conducted with multiple waste types in a 7-day period at the Kilauea Military Camp in Hawai’i. The emissions characterized were chosen based on regulatory emissions limits as well as their ability to cause adverse health effects on humans: particulate matter (PM), mercury, heavy metals, volatile organic compounds (VOCs), polyaromatic hydrocarbons (PAHs), and polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs). Three military waste feedstock compositions reflecting the variety of wastes to be encountered in theatre were investigated: standard waste (SW), standard waste with increased plastic content (HP), standard waste without SW food components but added first strike ration (FSR) food and packaging material (termed FSR). A fourth waste was collected from the Kilauea dumpster that served the dining facility and room lodging (KMC). Limited scrubber water and solid ash residue samples were collected to obtain a preliminary characterization of these effluents/residues.Gasifying SW, HP, and KMC resulted in similar PCDD/PCDF stack concentrations, 0.26-0.27 ng TEQ/m3 at 7% O2, while FSR waste generated a notably higher stack concentration of 0.68 ng TEQ/m3 at 7% O2. The PM emission

  16. Range-Based Auto-Focus Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Maracel Systems and Software Technologies, LLC proposes a revolutionary Range-Based Auto Focus (RBAF) system that will combine externally input range, such as might...

  17. Os processos auto-organizacionais do goalball

    National Research Council Canada - National Science Library

    Márcio Pereira Morato; Mariana Simões Pimentel Gomes; José Júlio Gavião de Almeida

    2012-01-01

    .... Distinguimos o ciclo auto-organizacional das equipes, um processo recursivo atrator de suas configurações. O histórico das relações entre as dimensões opostas das equipes representa o jogo...

  18. A novel auto-focus function

    Science.gov (United States)

    Wang, Jian; Chen, Hongbin

    2012-10-01

    The one key problem of passive auto-focus technique based on image is image definition criterion which is estimated by auto-focus function.This paper analyzes the limitation of traditional spatial domain auto-focus functions which are not sensitive to small changes of images,and presents a new auto-focus evaluation function which uses the combination filters to strengthen the image medium-frequency information.In order to evaluate the new function performance,the parameters of unimodality,accuracy,sensitivity,calculating cost are compared and analyzed.Compared with the traditional spatial domain evaluation functions,such as Brenner function,Laplacian function and Tenengrad function,the experimental results show that the new function has a fast calculation speed,and has a high sensitivity.

  19. Certifying Auto-Generated Flight Code

    Science.gov (United States)

    Denney, Ewen

    2008-01-01

    Model-based design and automated code generation are being used increasingly at NASA. Many NASA projects now use MathWorks Simulink and Real-Time Workshop for at least some of their modeling and code development. However, there are substantial obstacles to more widespread adoption of code generators in safety-critical domains. Since code generators are typically not qualified, there is no guarantee that their output is correct, and consequently the generated code still needs to be fully tested and certified. Moreover, the regeneration of code can require complete recertification, which offsets many of the advantages of using a generator. Indeed, manual review of autocode can be more challenging than for hand-written code. Since the direct V&V of code generators is too laborious and complicated due to their complex (and often proprietary) nature, we have developed a generator plug-in to support the certification of the auto-generated code. Specifically, the AutoCert tool supports certification by formally verifying that the generated code is free of different safety violations, by constructing an independently verifiable certificate, and by explaining its analysis in a textual form suitable for code reviews. The generated documentation also contains substantial tracing information, allowing users to trace between model, code, documentation, and V&V artifacts. This enables missions to obtain assurance about the safety and reliability of the code without excessive manual V&V effort and, as a consequence, eases the acceptance of code generators in safety-critical contexts. The generation of explicit certificates and textual reports is particularly well-suited to supporting independent V&V. The primary contribution of this approach is the combination of human-friendly documentation with formal analysis. The key technical idea is to exploit the idiomatic nature of auto-generated code in order to automatically infer logical annotations. The annotation inference algorithm

  20. Overheden bereid extra te betalen voor auto's op alternatieve brandstof

    NARCIS (Netherlands)

    Rijnsoever, F.J. van; Hagen, Paul

    2012-01-01

    De elektrische auto en een auto op groen gas worden door overheden hoger gewaardeerd dan de auto met reguliere verbrandingsmotor. Bovendien zijn overheden bereid extra te betalen voor een auto op alternatieve brandstof. Dit blijkt uit een masteronderzoek van de Universiteit Utrecht in opdracht

  1. PLC Based Hydraulic Auto Ladle System

    OpenAIRE

    Amogh Tayade; Anuja Chitre

    2014-01-01

    In this paper we have implemented a PLC based Hydraulic Auto Ladle System for Casting Department of Victory Precisions Pvt. Ltd. Chakan, Pune. This project work presents the study and design of PLC based Hydraulic Auto Ladle System. Aluminium pouring is the key process in Casting and Forging industry. Different products are manufactured by the company for automobile sector using aluminium. Programmable Logic Controller (PLC) is used for the automation of pouring process. Au...

  2. CONSIDERATIONS ON OBJECT-ORIENTED PROGRAMMING ENVIRONMENT AUTOCAD DRAWINGS

    Directory of Open Access Journals (Sweden)

    PINTILIE Alexandru

    2015-06-01

    Full Text Available In recent years, Low Cost CAD systems are widespread in the technical world. Currently, the highest-rated CAD system is AutoCAD due to the fact that in association with AutoLISP programming language covered a broad range of production needs. As a high-level programming language, AutoLISP provides an easy and efficient programming technique that leads to automation and parameterization of AutoCAD commands and reduces the time spending for designing the drawings. This paper aims to highlight the advantages of using AutoLISP programming environment in the 2D drafting and 3D modeling using AutoCAD tools.

  3. Using AutoCAD to improve the visibility of the organizational technological design

    Directory of Open Access Journals (Sweden)

    Lebedeva Irina Mikhailovna

    2014-01-01

    Full Text Available The article describes the issue of increasing the visibility of technological solutions in organizational-technological design. The ability to visualize the main stages of building process technology contributes to organic integration of all the requirements. A special role for the harmonious perception is played by correct display of the lighting facilities, shadowing. Realistic shadows help to analyze the rooms’ insolation of the designed facility and the surrounding areas. We give a justification for the use of AutoCAD in order to automate the process of visualizing the results of organizational-technological design. The author describes the methods of obtaining realistic natural lighting in AutoCAD without significantly increasing the complexity of the process. Engineering companies in 46 % of cases use the software AutoCAD in order to create construction plans. AutoCAD has a variety of possibilities and is constantly evolving. Continuation is one of the benefits of this program. AutoCAD is unique in terms of customization, because, apart from instruction languages, it has two built-in programming languages: AutoLISP and VisualBasic. Because of these specific features AutoCAD allows to create any applications related to graphics implementation. Constant monitoring of lightning changes allows finding the appropriate in terms of aesthetics, ergonomics and insolation decisions on planning and associating a building or structure to the environment. Solar lighting is simulated by a combination of several directional lightning point sources. The author offers a brief description of the program algorithm, which allows automatically managing lighting settings and creating a file with a realistic visualization of the design solutions.

  4. AutoCAD 2012 and AutoCAD LT 2012 Bible

    CERN Document Server

    Finkelstein, Ellen

    2011-01-01

    The latest version of this perennial favorite, in-depth, reference-tutorial This top-selling book has been updated by AutoCAD guru and author Ellen Finkelstein to provide you with the very latest coverage of both AutoCAD 2012 and AutoCAD LT 2012. It begins with a Quick Start tutorial, so you start creating right away. From there, the book covers so much in-depth material on AutoCAD that it is said that even Autodesk employees keep this comprehensive book at their desks. A DVD is included that features before-and-after drawings of all the tutorials and plenty of great examples from AutoCAD prof

  5. AutoCAD platform customization user interface and beyond

    CERN Document Server

    Ambrosius, Lee

    2014-01-01

    Make AutoCAD your own with powerful personalization options Options for AutoCAD customization are typically the domain of administrators, but savvy users can perform their own customizations to personalize AutoCAD. Until recently, most users never thought to customize the AutoCAD platform to meet their specific needs, instead leaving it to administrators. If you are an AutoCAD user who wants to ramp up personalization options in your favorite software, AutoCAD Platform Customization: User Interface and Beyond is the perfect resource for you. Author Lee Ambrosius is recognized as a leader in Au

  6. Satisfaction with early retirement: making choices in the auto industry.

    Science.gov (United States)

    Hardy, M A; Quadagno, J

    1995-07-01

    In recent decades, the expanded availability of early retirement incentive plans has allowed an increasing number of workers to retire at an age younger than normally allowed by their pension plans. On the surface, these retirement incentives appear to offer older workers more flexibility in deciding when to retire. However, the offer of early retirement incentives frequently occurs when employers are attempting to reduce employment; therefore, the opportunity for early retirement may be counterbalanced by downsizing goals that place older workers' continued employment in jeopardy. Early retirement incentive programs are thereby characterized by an unusual combination of inducement and coercion. In this study, we examined how the structure of the early retirement program shapes the way older male auto workers evaluate their retirement transitions. We conclude that the structure of the early retirement program, the timing of the retirement decision, and job security are important in framing the retirement transition and in distinguishing levels of satisfaction with the retirement experience.

  7. Auto-tuning for NMR probe using LabVIEW

    Science.gov (United States)

    Quen, Carmen; Pham, Stephanie; Bernal, Oscar

    2014-03-01

    Typical manual NMR-tuning method is not suitable for broadband spectra spanning several megahertz linewidths. Among the main problems encountered during manual tuning are pulse-power reproducibility, baselines, and transmission line reflections, to name a few. We present a design of an auto-tuning system using graphic programming language, LabVIEW, to minimize these problems. The program uses a simplified model of the NMR probe conditions near perfect tuning to mimic the tuning process and predict the position of the capacitor shafts needed to achieve the desirable impedance. The tuning capacitors of the probe are controlled by stepper motors through a LabVIEW/computer interface. Our program calculates the effective capacitance needed to tune the probe and provides controlling parameters to advance the motors in the right direction. The impedance reading of a network analyzer can be used to correct the model parameters in real time for feedback control.

  8. Parallel auto-correlative statistics with VTK.

    Energy Technology Data Exchange (ETDEWEB)

    Pebay, Philippe Pierre; Bennett, Janine Camille

    2013-08-01

    This report summarizes existing statistical engines in VTK and presents both the serial and parallel auto-correlative statistics engines. It is a sequel to [PT08, BPRT09b, PT09, BPT09, PT10] which studied the parallel descriptive, correlative, multi-correlative, principal component analysis, contingency, k-means, and order statistics engines. The ease of use of the new parallel auto-correlative statistics engine is illustrated by the means of C++ code snippets and algorithm verification is provided. This report justifies the design of the statistics engines with parallel scalability in mind, and provides scalability and speed-up analysis results for the autocorrelative statistics engine.

  9. Stochastic single-gene auto-regulation

    CERN Document Server

    Aquino, Tomás; Nunes, Ana

    2011-01-01

    A detailed stochastic model of single-gene auto-regulation is established and its solutions are explored when mRNA dynamics is fast compared with protein dynamics and in the opposite regime. The model includes all the sources of randomness that are intrinsic to the auto-regulation process. The timescale separation allows the derivation of analytic expressions for the equilibrium distributions of protein and mRNA. These distributions are shown to be well described in the continuous approximation, which is then used to discuss the qualitative features of the protein equilibrium distributions as a function of the biological parameters in the fast mRNA regime.

  10. AutoCAD 2012 and AutoCAD LT 2012 No Experience Required

    CERN Document Server

    Gladfelter, Donnie

    2011-01-01

    The perfect step-by-step introduction to Autodesk's powerful architectural design software With this essential guide, you'll learn how to plan, develop, document, and present a complete AutoCAD project by building a summer cabin from start to finish. You can follow each step sequentially or jump in at any point by downloading the drawing files from the book's companion web site. You'll also master all essential AutoCAD features, get a thorough grounding in the basics, learn the very latest industry standards and techniques, and quickly become productive with AutoCAD 2012.Features concise expla

  11. AutoCAD 2015 and AutoCAD LT 2015 essentials

    CERN Document Server

    Onstott, Scott

    2014-01-01

    Step-by-step instructions for the AutoCAD fundamentals AutoCAD 2015 Essentials contains 400 pages of full-color, comprehensive instruction on the world's top drafting and architecture software. This 2015 edition features architectural, manufacturing, and landscape architecture examples. And like previous editions, the detailed guide introduces core concepts using interactive tutorials and open-ended projects, which can be completed in any order, thanks to downloadable data sets (an especially useful feature for students and professionals studying for Autodesk AutoCAD certification). Unlike man

  12. [Failure to perform auto-test of anaesthesia machine at the opening of the operating room].

    Science.gov (United States)

    Suria, S; Puizillout, J-M; Baguenard, P; Bourgain, J-L

    2010-12-01

    controls performed at the opening of the operating room include the anesthesia machine auto-test. Omitting the preoperative checklist is unsafe for the patient and increases the risk of possible breakdowns. The purpose of this study was to evaluate the incidence and the situations in which the auto-test of the machine was not performed at the opening of the operative room. from a database including 55 195 cases between 1st January 2002 and 31st July 2009, a query identified cases in which the auto-test of the anaesthesia machine was omitted and the cases in which anaesthesia was made in spite of the failure of this test. Clinical circumstances were analyzed and anaesthetist and/or nurse anaesthetist were identified from the computerized anaesthesia record. one hundred and ninety cases (1.24%) were identified. Seventy-three percent of the omissions of the auto-test occurred while on duty whereas 85% of the failures of the auto-test took place at the beginning of the scheduled program. Individual factor was identified since three anaesthesiologists out of 22 were responsible for 49% of omissions on duty and one nurse anesthetist was responsible for 18% of the use of a failed machine and 30% of the omission of the auto-test. the auto-test of the anesthesia machine was correctly made in most cases but there are still situations where the checklist wasn't carried out. Therefore, the human factor seems important and justifies to be taken into account. 2010 Elsevier Masson SAS. All rights reserved.

  13. RayTrace: A Simplified Ray Tracing Software for use in AutoCad

    DEFF Research Database (Denmark)

    Reimann, Gregers Peter; Tang, C.K.

    2005-01-01

    A design aid tool for testing and development of daylighting systems was developed. A simplified ray tracing software was programmed in Lisp for AutoCad. Only fully specularly reflective, fully transparent and fully absorbant surfaces can be defined in the software. The software is therefore best...

  14. The Frustrations of Digital Fabrication: An Auto/Ethnographic Exploration of "3D Making" in School

    Science.gov (United States)

    Nemorin, Selena

    2017-01-01

    Following initial educational enthusiasms for 'Making' technologies and the 'Maker Movement', increasing numbers of students are now using digital fabrication programs and equipment in school. Given the current lack of empirical research exploring the realities of Making as a school activity, this paper presents an in-depth auto/ethnographic…

  15. Trajectory Auto-Corrected image reconstruction.

    Science.gov (United States)

    Ianni, Julianna D; Grissom, William A

    2016-09-01

    To estimate k-space trajectory errors in non-Cartesian acquisitions and reconstruct distortion-free images, without trajectory measurements or gradient calibrations. The Trajectory Auto-Corrected image Reconstruction method jointly estimates k-space trajectory errors and images, based on SENSE and SPIRiT parallel imaging reconstruction. The underlying idea is that parallel imaging and oversampling in the center of k-space provides data redundancy that can be exploited to simultaneously reconstruct images and correct trajectory errors. Trajectory errors are represented as weighted sums of trajectory-dependent error basis functions, the coefficients of which are estimated using gradient-based optimization. Trajectory Auto-Corrected image Reconstruction was applied to reconstruct images and errors in golden angle radial, center-out radial, and spiral in vivo 7 Tesla brain acquisitions in five subjects. Compared to reconstructions using nominal trajectories, Trajectory auto-corrected image reconstructions contained considerably less blurring and streaking and were of similar quality to images reconstructed using measured k-space trajectories in the center-out radial and spiral cases. Reconstruction cost function reductions and improvements in normalized image gradient squared were also similar to those for images reconstructed using measured trajectories. Trajectory Auto-Corrected image Reconstruction enables non-Cartesian image reconstructions free from trajectory errors without the need for separate gradient calibrations or trajectory measurements. Magn Reson Med 76:757-768, 2016. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.

  16. MICRO AUTO GASIFICATION SYSTEM: EMISSIONS CHARACTERIZATION

    Science.gov (United States)

    A compact, CONEX-housed waste to energy unit, Micro Auto Gasification System (MAGS), was characterized for air emissions from burning of military waste types. The MAGS unit is a dual chamber gasifier with a secondary diesel-fired combustor. Eight tests were conducted with multipl...

  17. Selectively personalizing query auto-completion

    NARCIS (Netherlands)

    Cai, F.; de Rijke, M.

    2016-01-01

    Query auto-completion (QAC) is being used by many of today's search engines. It helps searchers formulate queries by providing a list of query completions after entering an initial prefix of a query. To cater for a user's specific information needs, personalized QAC strategies use a searcher's

  18. Auto-correlograms and auto-regressive models of trace metal distributions in Cochin backwaters

    Digital Repository Service at National Institute of Oceanography (India)

    Jayalakshmy, K.V.; Sankaranarayanan, V.N.

    Auto-correlation technique has been applied to study fluctuations in concentration profiles of chemical species in Cochin Backwaters (Kerala, India). No stability in time can be detected for particulate Mn at all stations, for Fe at stations 1...

  19. Letselgevolgen van auto-inzittenden na een auto-ongeval : een volksgezondheidkundige studie

    NARCIS (Netherlands)

    Clay, Willem

    1986-01-01

    vraagstelling gaat over het verlies aan volksgezondheid door auto-ongevallen, deze verliespost is goed toegankelijk voor onderzoek, omdat de oorzaak van het verlies-botsingsenergie duidelijk is. ... Zie: Samenvatting

  20. 46 CFR 78.19-1 - Use of auto pilot.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 3 2010-10-01 2010-10-01 false Use of auto pilot. 78.19-1 Section 78.19-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PASSENGER VESSELS OPERATIONS Auto Pilot § 78.19-1 Use of auto pilot. Except as provided in 33 CFR 164.15, when the automatic pilot is used in— (a...

  1. 46 CFR 97.16-1 - Use of auto pilot.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Use of auto pilot. 97.16-1 Section 97.16-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CARGO AND MISCELLANEOUS VESSELS OPERATIONS Auto Pilot § 97.16-1 Use of auto pilot. Except as provided in 33 CFR 164.15, when the automatic pilot is used...

  2. Conversations with AutoTutor Help Students Learn

    Science.gov (United States)

    Graesser, Arthur C.

    2016-01-01

    AutoTutor helps students learn by holding a conversation in natural language. AutoTutor is adaptive to the learners' actions, verbal contributions, and in some systems their emotions. Many of AutoTutor's conversation patterns simulate human tutoring, but other patterns implement ideal pedagogies that open the door to computer tutors eclipsing…

  3. Clementine auto exposure control software

    Energy Technology Data Exchange (ETDEWEB)

    Arnold, E. [Lawrence Livermore National Lab., CA (United States)

    1994-11-15

    The primary mission of the Clementine program was to test technology developed under the auspices of BMDO (the Ballistic Missile Defense Organization). A secondary goal of the program was to provide astronomical data to the scientific and educational community. The mission plan developed to accomplish these goals included complete mapping of the lunar surface and a close fly-by of a near-Earth asteroid, 1620 Geographos. Exposure control for the Clementine mission was driven by mission phase requirements and sensor characteristics. Thus, there were a total of twelve algorithms developed for three primary mission phases and the four imaging sensors (two additional sensors operated as star trackers). The three mission phases in question were lunar mapping, distant observation of the asteroid for the purpose of tracking, and close-up viewing (as close as 100 Km) of Geographos. The four non-star tracker sensors consisted of an Ultra Violet/Visible (UV/Vis) camera, a High Resolution (HiRes) camera with a built-in LIDAR (Light Detection And Ranging) unit, a Near Infrared (NIR) camera, and a Long Wave InfraRed (LWIR) camera. Due to lack of test time and uncertainties about the imaging environment, numerous input parameters were provided in the algorithms to allow extensive tuning of the exposure control during the mission.

  4. Risk Evaluation in Auto Spare Parts Transport Based on the AHP Method

    OpenAIRE

    Zeng Rong; Xu Chang

    2017-01-01

    By way of example we analyze various risks exist in auto spare parts transportation, building engineering logistics risk evaluation index system of auto spare parts transportation, and the introduction of AHP, be more rational auto spare parts transportation risk assessment methods, strengthen risk management auto spare parts auto spare parts transportation to provide a reference for other engineering logistics auto spare parts transportation.

  5. PERI - Auto-tuning Memory Intensive Kernels for Multicore

    Energy Technology Data Exchange (ETDEWEB)

    Bailey, David H; Williams, Samuel; Datta, Kaushik; Carter, Jonathan; Oliker, Leonid; Shalf, John; Yelick, Katherine; Bailey, David H

    2008-06-24

    We present an auto-tuning approach to optimize application performance on emerging multicore architectures. The methodology extends the idea of search-based performance optimizations, popular in linear algebra and FFT libraries, to application-specific computational kernels. Our work applies this strategy to Sparse Matrix Vector Multiplication (SpMV), the explicit heat equation PDE on a regular grid (Stencil), and a lattice Boltzmann application (LBMHD). We explore one of the broadest sets of multicore architectures in the HPC literature, including the Intel Xeon Clovertown, AMD Opteron Barcelona, Sun Victoria Falls, and the Sony-Toshiba-IBM (STI) Cell. Rather than hand-tuning each kernel for each system, we develop a code generator for each kernel that allows us to identify a highly optimized version for each platform, while amortizing the human programming effort. Results show that our auto-tuned kernel applications often achieve a better than 4X improvement compared with the original code. Additionally, we analyze a Roofline performance model for each platform to reveal hardware bottlenecks and software challenges for future multicore systems and applications.

  6. Auto-communicating micro-orientalism

    DEFF Research Database (Denmark)

    Ren, Carina Bregnholm; Ooi, Can-Seng

    2013-01-01

    Using the concepts of auto-communication and micro-Orientalism, this article argues that nation branding at World Expos produces and propagates notions of difference and Otherness. We examine how Denmark presents itself in China, and how the message inevitably tells how the Danish authorities view...... the Chinese. Using the Danish ‘Welfairytales’ pavilion at the 2010 World Expo in Shanghai, we show how the national self is performed in two versions. One attempts to communicate ‘the good Danish life’ to the Danes themselves, while the other claims Occidental superiority. The case shows how the Danish...... exhibition is performed and regulated as sustainable and authentic and how in spite of its seemingly dialogical and interactive layout, a number of auto-communicative and micro-Orientalist practices are enacted. This study is based on field participation, observations and interviews. Public sources...

  7. Os processos auto-organizacionais do goalball

    Directory of Open Access Journals (Sweden)

    Márcio Pereira Morato

    2012-09-01

    Full Text Available O goalball é uma modalidade coletiva criada para pessoas com deficiência visual e baseada no tato e na audição. Partindo das contribuições das teorias sistêmicas, e entendendo as equipes e o jogo como sistemas, objetivamos interpretar os padrões e processos auto-organizacionais da modalidade. Para tal, observamos vinte jogos das Paralimpíadas de 2008. Distinguimos o ciclo auto-organizacional das equipes, um processo recursivo atrator de suas configurações. O histórico das relações entre as dimensões opostas das equipes representa o jogo. Cessada a interação cessa o jogo, permanecendo seu registro, que atuará recursivamente nas futuras preparações das equipes, oportunizando novos processos geradores de novos produtos, num interminável ciclo cuja causa e efeito, processo e produto se interligam.

  8. A model of auto immune response

    OpenAIRE

    Peterson, James K.; Kesson, Alison M.; King, Nicholas J. C.

    2017-01-01

    Background In this work, we develop a theoretical model of an auto immune response. This is based on modifications of standard second messenger trigger models using both signalling pathways and diffusion and a macro level dynamic systems approximation to the response of a triggering agent such as a virus, bacteria or environmental toxin. Results We show that there, in general, will be self damage effects whenever the triggering agent?s effect on the host can be separated into two distinct cla...

  9. AutoRoute Rapid Flood Inundation Model

    Science.gov (United States)

    2013-03-01

    cross-section data does not exist. As such, the AutoRoute model is not meant to be as accurate as models such as HEC - RAS (U.S. Army Engineer...such as HEC - RAS assume that the defined low point of cross sections must be connected. However, in this approach the channel is assumed to be defined...Res. 33(2): 309-319. U.S. Army Engineer Hydrologic Engineering Center. 2010. “ HEC - RAS : River Analysis System, User’s Manual, Version 4.1.” Davis

  10. Experimental Study of Magnetic Field Production and Dielectric Breakdown of Auto-Magnetizing Liners

    Science.gov (United States)

    Shipley, Gabriel; Awe, Thomas; Hutchinson, Trevor; Hutsel, Brian; Slutz, Stephen; Lamppa, Derek

    2017-10-01

    AutoMag liners premagnetize the fuel in MagLIF targets and provide enhanced x-ray diagnostic access and increased current delivery without requiring external field coils. AutoMag liners are composite liners made with discrete metallic helical conduction paths separated by insulating material. First, a low dI/dt ``foot'' current pulse (1 MA in 100 ns) premagnetizes the fuel. Next, a higher dI/dt pulse with larger induced electric field initiates breakdown on the composite liner's; surface, switching the current from helical to axial to implode the liner. Experiments on MYKONOS have tested the premagnetization and breakdown phases of AutoMag and demonstrate axial magnetic fields above 90 Tesla for a 550 kA peak current pulse. Electric fields of 17 MV/m have been generated before breakdown. AutoMag may enhance MagLIF performance by increasing the premagnetization strength significantly above 30 T, thus reducing thermal-conduction losses and mitigating anomalous diffusion of magnetic field out of hotter fuel regions, by, for example, the Nernst thermoelectric effect. This project was funded in part by Sandia's Laboratory Directed Research and Development Program (Projects No. 200169 and 195306).

  11. Web proxy auto discovery for the WLCG

    CERN Document Server

    Dykstra, D; Blumenfeld, B; De Salvo, A; Dewhurst, A; Verguilov, V

    2017-01-01

    All four of the LHC experiments depend on web proxies (that is, squids) at each grid site to support software distribution by the CernVM FileSystem (CVMFS). CMS and ATLAS also use web proxies for conditions data distributed through the Frontier Distributed Database caching system. ATLAS & CMS each have their own methods for their grid jobs to find out which web proxies to use for Frontier at each site, and CVMFS has a third method. Those diverse methods limit usability and flexibility, particularly for opportunistic use cases, where an experiment’s jobs are run at sites that do not primarily support that experiment. This paper describes a new Worldwide LHC Computing Grid (WLCG) system for discovering the addresses of web proxies. The system is based on an internet standard called Web Proxy Auto Discovery (WPAD). WPAD is in turn based on another standard called Proxy Auto Configuration (PAC). Both the Frontier and CVMFS clients support this standard. The input into the WLCG system comes from squids regis...

  12. Economic evaluation of epinephrine auto-injectors for peanut allergy.

    Science.gov (United States)

    Shaker, Marcus; Bean, Katherine; Verdi, Marylee

    2017-08-01

    Three commercial epinephrine auto-injectors were available in the United States in the summer of 2016: EpiPen, Adrenaclick, and epinephrine injection, USP auto-injector. To describe the variation in pharmacy costs among epinephrine auto-injector devices in New England and evaluate the additional expense associated with incremental auto-injector costs. Decision analysis software was used to evaluate costs of the most and least expensive epinephrine auto-injector devices for children with peanut allergy. To evaluate regional variation in epinephrine auto-injector costs, a random sample of New England national and corporate pharmacies was compared with a convenience sample of pharmacies from 10 Canadian provinces. Assuming prescriptions written for 2 double epinephrine packs each year (home and school), the mean costs of food allergy over the 20-year model horizon totaled $58,667 (95% confidence interval [CI] $57,745-$59,588) when EpiPen was prescribed and $45,588 (95% CI $44,873-$46,304) when epinephrine injection, USP auto-injector was prescribed. No effectiveness differences were evident between groups, with 17.19 (95% CI 17.11-17.27) quality-adjusted life years accruing for each subject. The incremental cost per episode of anaphylaxis treated with epinephrine over the model horizon was $12,576 for EpiPen vs epinephrine injection, USP auto-injector. EpiPen costs were lowest at Canadian pharmacies ($96, 95% CI $85-$107). There was price consistency between corporate and independent pharmacies throughout New England by device brand, with the epinephrine injection, USP auto-injector being the most affordable device. Cost differences among epinephrine auto-injectors were significant. More expensive auto-injector brands did not appear to provide incremental benefit. Copyright © 2017 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  13. Heavy Metals in Soils of auto- mechanic shops and refuse ...

    African Journals Online (AJOL)

    Michael Horsfall

    ABSTRACT: Dumpsites soil samples in Apir and North Bank Auto- mechanic workshop locations in Makurdi, ... soils. It will also form a baseline of the environmental effects of indiscriminate dumping of refuse. Previous studies have not recognized auto-mechanic shops ... or article for which no direct use is envisaged but.

  14. Auto concept y rasgos de personalidad: Un estudio correlacional

    Directory of Open Access Journals (Sweden)

    Débora Cecílio Fernandes

    Full Text Available Este estudio ha investigado las relaciones entre los rasgos de personalidad y auto concepto. Fueron aplicadas la Escala de Traços de Personalidade para Crianças y la Escala de Autoconceito Infanto-Juvenil en 389 niños, con edad de 8 a 10 años de escuelas públicas y particulares. Se han hallado diferencias de sexo para casi todas las medidas hechas. Para los varones, ha sido observado correlaciones positivas entre extroversión y auto conceptos escolar y familiar, neuroticismo y psicoticismo con auto conceptos personal y social, y sociabilidad con auto concepto familiar; y correlaciones negativas entre extroversión y auto concepto social, psicoticismo y auto concepto familiar, y sociabilidad y auto concepto personal. Para las niñas, fueron observadas correlaciones positivas entre el auto concepto social y psicoticismo y sociabilidad con el familiar; y correlaciones negativas entre extroversión y el social, psicoticismo y neuroticismo con el familiar. Los análisis de los grupos extremos confirmaron los datos encontrados.

  15. Kommest Auto ostmisest huvitub ka Hillar Teder / Andres Eilart

    Index Scriptorium Estoniae

    Eilart, Andres

    2008-01-01

    Kommest Auto ostmise vastu tunnevad huvi suurärimees Andres Sarri, Rootsis Peugeot' sõidukeid müüv Taani päritolu K. W. Bruun Import ja multimiljonär Hillar Teder, kellele kuulub Audisid müüv Reval Auto

  16. Auto-immune encefalitis in de psychiatrische praktijk

    NARCIS (Netherlands)

    de Witte, L; Kromkamp, M|info:eu-repo/dai/nl/241613876; Schoenmaker, N; van Mierlo, H C|info:eu-repo/dai/nl/413967263; Martinez-Martínez, P; Palmen, S J M; Sommer, I E C|info:eu-repo/dai/nl/258791519

    BACKGROUND: Our knowledge about auto-immune limbic encephalitis is increasing rapidly and it is now evident that patients with this disease can present with psychiatric symptoms. AIM: To propose practical guidelines for the recognition and diagnosis of an underlying auto-immune limbic encephalitis

  17. Rüütmann taandub Kommest Auto juhtimisest / Kaisa Tahlfeld

    Index Scriptorium Estoniae

    Tahlfeld, Kaisa

    2007-01-01

    AS-i Kommest Auto asutaja ja omanik Toomas Rüütmann loobub ettevõtte juhtimisest, kuid jätkab juhatuse liikmena ning keskendub eksportturgudele ja koostööle edasimüüjatega. Kommest Auto uueks juhiks saab Raido Toonekurg. Lisa: Mis on mis; Taust

  18. 46 CFR 131.960 - Use of auto-pilot.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Use of auto-pilot. 131.960 Section 131.960 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS OPERATIONS Miscellaneous § 131.960 Use of auto-pilot. When the automatic pilot is used in areas of high traffic density...

  19. 46 CFR 167.65-35 - Use of auto pilot.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Use of auto pilot. 167.65-35 Section 167.65-35 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS PUBLIC NAUTICAL SCHOOL SHIPS Special Operating Requirements § 167.65-35 Use of auto pilot. Except as provided in 33 CFR 164.15, when...

  20. 46 CFR 185.360 - Use of auto pilot.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Use of auto pilot. 185.360 Section 185.360 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Miscellaneous Operating Requirements § 185.360 Use of auto pilot. Whenever an automatic pilot is...

  1. 46 CFR 122.360 - Use of auto pilot.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Use of auto pilot. 122.360 Section 122.360 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS CARRYING MORE THAN 150... Requirements § 122.360 Use of auto pilot. Whenever an automatic pilot is used the master shall ensure that: (a...

  2. 46 CFR 109.585 - Use of auto pilot.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Use of auto pilot. 109.585 Section 109.585 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS OPERATIONS Miscellaneous § 109.585 Use of auto pilot. Except as provided in 33 CFR 164.15, when the automatic pilot is used...

  3. Auto-Clustering using Particle Swarm Optimization and Bacterial Foraging

    DEFF Research Database (Denmark)

    Rutkowski Olesen, Jakob; Cordero, Jorge; Zeng, Yifeng

    2009-01-01

    This paper presents a hybrid approach for clustering based on particle swarm optimization (PSO) and bacteria foraging algorithms (BFA). The new method AutoCPB (Auto-Clustering based on particle bacterial foraging) makes use of autonomous agents whose primary objective is to cluster chunks of data...

  4. Sarri võttis Talleksiga taanlastelt Saksa Auto / Villy Paimets

    Index Scriptorium Estoniae

    Paimets, Villy, 1972-

    2005-01-01

    Andres Sarri poolt kontrollitav AS Talleks ostis Taani partnerilt Semler Holding välja 50-protsendilise osaluse AS-is Saksa Auto. Lisa: Viimastel aastatel eestlaste poolt välja ostetud ettevõtted. Diagramm: Saksa Auto tulemused paranesid mullu märgatavalt. Vt. samas: Sarri: me ei tee halbu tehinguid; Peeter Raidla. Tuleristsed 90ndate alguse võimuvõitlusest

  5. A Survey of Query Auto Completion in Information Retrieval

    NARCIS (Netherlands)

    Cai, F.; de Rijke, M.

    2016-01-01

    In information retrieval, query auto completion (QAC), also known as type-ahead [Xiao et al., 2013, Cai et al., 2014b] and auto-complete suggestion [Jain and Mishne, 2010], refers to the following functionality: given a prefix consisting of a number of characters entered into a search box, the user

  6. AutoPyFactory and the Cloud

    CERN Document Server

    Caballero, J; The ATLAS collaboration; Love, P

    2013-01-01

    AutoPyFactory (APF) is a next-generation pilot submission framework that has been used as part of the ATLAS workload management system (PANDA) for two years. APF is reliable, scalable, and offers easy and flexible configuration. Using a plugin-based architecture, APF polls for information from configured information and batch systems (including grid sites), decides how many additional pilot jobs are needed, and submits them. With the advent of cloud computing, providing resources goes beyond submitting pilots to grid sites. Now, the resources on which the pilot will run also need to be managed. Handling both pilot submission and controlling the virtual machine life cycle (creation, retirement, and termination) from the same framework allows robust and efficient management of the process. In this paper we describe the design and implementation of these virtual machine management capabilities of APF. Expanding on our plugin-based approach, we allow cascades of virtual resources associated with a job queue. A si...

  7. Auto-choreography: Animating Sentient Archives

    Directory of Open Access Journals (Sweden)

    Kim Satchell

    2010-03-01

    Full Text Available The stories lives tell, the narratives they follow and the spaces they embody are critical to articulating the conditions of everyday life. This resonates in the fraught relations within and between surf cultures, affluent societies and economic development. In the context of Rural Cultural Studies the analysis of coastal place allows for a combination of self-reflexive, critical and transformative modes of inquiry. This pedagogy of the coast offers innovative approaches to contemporary anthropogenic and existential challenges. For the Ecological Humanities, adjusting to living synergistically requires dialogue, ethical frameworks and care. This includes attention to the more-than human world and the non-human inhabitants with whose lives people become entangled in the mutuality of wandering paths and shared haunts. The imaginary-material architectures and geographies of these samples of coastal life, are topographies woven of spatiality and contemporary coastal writing. These contemplations attempt to sketch performative interactions from the auto-choreography animating sentient archives.

  8. Female Infertility and Serum Auto-antibodies: a Systematic Review.

    Science.gov (United States)

    Deroux, Alban; Dumestre-Perard, Chantal; Dunand-Faure, Camille; Bouillet, Laurence; Hoffmann, Pascale

    2017-08-01

    On average, 10 % of infertile couples have unexplained infertility. Auto-immune disease (systemic lupus erythematosus, anti-phospholipid syndrome) accounts for a part of these cases. In the last 20 years, aspecific auto-immunity, defined as positivity of auto-antibodies in blood sample without clinical or biological criteria for defined diseases, has been evoked in a subpopulation of infertile women. A systematic review was performed (PUBMED) using the MESH search terms "infertility" and "auto-immunity" or "reproductive technique" or "assisted reproduction" or "in vitro fertilization" and "auto-immunity." We retained clinical and physiopathological studies that were applicable to the clinician in assuming joint management of both infertility associated with serum auto-antibodies in women. Thyroid auto-immunity which affects thyroid function could be a cause of infertility; even in euthyroidia, the presence of anti-thyroperoxydase antibodies and/or thyroglobulin are related to infertility. The presence of anti-phospholipid (APL) and/or anti-nuclear (ANA) antibodies seems to be more frequent in the population of infertile women; serum auto-antibodies are associated with early ovarian failure, itself responsible for fertility disorders. However, there exist few publications on this topic. The methods of dosage, as well as the clinical criteria of unexplained infertility deserve to be standardized to allow a precise response to the question of the role of serum auto-antibodies in these women. The direct pathogenesis of this auto-immunity is unknown, but therapeutic immunomodulators, prescribed on a case-by-case basis, could favor pregnancy even in cases of unexplained primary or secondary infertility.

  9. Performance Optimization and Auto-Tuning

    Energy Technology Data Exchange (ETDEWEB)

    Howison, Mark

    2012-10-01

    In the broader computational research community, one subject of recent research is the problem of adapting algorithms to make effective use of multi- and many-core processors. Effective use of these architectures, which have complex memory hierarchies with many layers of cache, typically involves a careful examination of how an algorithm moves data through the memory hierarchy. Unfortunately, there is often a non-obvious relationship between algorithmic parameters like blocking strategies, and their impact on memory utilization, and, in turn, the relationship with runtime performance. Auto-tuning is an empirical method used to discover optimal values for tunable algorithmic parameters under such circumstances. The challenge is compounded by the fact that the settings that produce the best performance for a given problem and a given platform may not be the best for a different problem on the same platform, or the same problem on a different platform. The high performance visualization research community has begun to explore and adapt the principles of auto-tuning for the purpose of optimizing codes on modern multi- and many-core processors. This report focuses on how performance optimization studies reveal a dramatic variation in performance for two fundamental visualization algorithms: one based on a stencil operation having structured, uniform memory access, and the other is ray casting volume rendering, which uses unstructured memory access patterns. The two case studies highlighted in this report show the extra effort required to optimize such codes by adjusting the tunable algorithmic parameters can return substantial gains in performance. Additionally, these case studies also explore the potential impact of and the interaction between algorithmic optimizations and tunable algorithmic parameters, along with the potential performance gains resulting from leveraging architecture-specific features.

  10. Analysis on the Workspace of Six-degrees-of-freedom Industrial Robot Based on AutoCAD

    Directory of Open Access Journals (Sweden)

    Li Jin-quan

    2017-01-01

    Full Text Available This research discusses the workspace of the industrial robot with six degrees of freedom(6-DOF based on AutoCAD platform. Based on the analysis of the overall configuration of the robot, this research establishes the kinematic mathematical model of the industrial robot by using DH parameters, and then solves the workspace of the robot consequently. In the AutoCAD, Auto Lisp language program is adopted to simulate the two-dimensional(2D and three-dimensional(3D space of the robot. Software user interface is written by using the dialog box control language of Visual LISP. At last, the research analyzes the trend of the shape and direction of the workspace when the length and angle range of the robot are changed. This research lays the foundation for the design, control and planning of industrial robots.

  11. Automatic detection of AutoPEEP during controlled mechanical ventilation

    Directory of Open Access Journals (Sweden)

    Nguyen Quang-Thang

    2012-06-01

    Full Text Available Abstract Background Dynamic hyperinflation, hereafter called AutoPEEP (auto-positive end expiratory pressure with some slight language abuse, is a frequent deleterious phenomenon in patients undergoing mechanical ventilation. Although not readily quantifiable, AutoPEEP can be recognized on the expiratory portion of the flow waveform. If expiratory flow does not return to zero before the next inspiration, AutoPEEP is present. This simple detection however requires the eye of an expert clinician at the patient’s bedside. An automatic detection of AutoPEEP should be helpful to optimize care. Methods In this paper, a platform for automatic detection of AutoPEEP based on the flow signal available on most of recent mechanical ventilators is introduced. The detection algorithms are developed on the basis of robust non-parametric hypothesis testings that require no prior information on the signal distribution. In particular, two detectors are proposed: one is based on SNT (Signal Norm Testing and the other is an extension of SNT in the sequential framework. The performance assessment was carried out on a respiratory system analog and ex-vivo on various retrospectively acquired patient curves. Results The experiment results have shown that the proposed algorithm provides relevant AutoPEEP detection on both simulated and real data. The analysis of clinical data has shown that the proposed detectors can be used to automatically detect AutoPEEP with an accuracy of 93% and a recall (sensitivity of 90%. Conclusions The proposed platform provides an automatic early detection of AutoPEEP. Such functionality can be integrated in the currently used mechanical ventilator for continuous monitoring of the patient-ventilator interface and, therefore, alleviate the clinician task.

  12. Web Proxy Auto Discovery for the WLCG

    Science.gov (United States)

    Dykstra, D.; Blomer, J.; Blumenfeld, B.; De Salvo, A.; Dewhurst, A.; Verguilov, V.

    2017-10-01

    All four of the LHC experiments depend on web proxies (that is, squids) at each grid site to support software distribution by the CernVM FileSystem (CVMFS). CMS and ATLAS also use web proxies for conditions data distributed through the Frontier Distributed Database caching system. ATLAS & CMS each have their own methods for their grid jobs to find out which web proxies to use for Frontier at each site, and CVMFS has a third method. Those diverse methods limit usability and flexibility, particularly for opportunistic use cases, where an experiment’s jobs are run at sites that do not primarily support that experiment. This paper describes a new Worldwide LHC Computing Grid (WLCG) system for discovering the addresses of web proxies. The system is based on an internet standard called Web Proxy Auto Discovery (WPAD). WPAD is in turn based on another standard called Proxy Auto Configuration (PAC). Both the Frontier and CVMFS clients support this standard. The input into the WLCG system comes from squids registered in the ATLAS Grid Information System (AGIS) and CMS SITECONF files, cross-checked with squids registered by sites in the Grid Configuration Database (GOCDB) and the OSG Information Management (OIM) system, and combined with some exceptions manually configured by people from ATLAS and CMS who operate WLCG Squid monitoring. WPAD servers at CERN respond to http requests from grid nodes all over the world with a PAC file that lists available web proxies, based on IP addresses matched from a database that contains the IP address ranges registered to organizations. Large grid sites are encouraged to supply their own WPAD web servers for more flexibility, to avoid being affected by short term long distance network outages, and to offload the WLCG WPAD servers at CERN. The CERN WPAD servers additionally support requests from jobs running at non-grid sites (particularly for LHC@Home) which they direct to the nearest publicly accessible web proxy servers. The responses

  13. Sistem Informasi Penjualan Pemasangan Kacafilm “HS Auto Film"

    Directory of Open Access Journals (Sweden)

    Noer Tjahja Moekthi Pratjitana

    2013-07-01

    Full Text Available The growing market share in many business areas especially in service area is causing the use of conventional accounting system being ineffective. One of the companies which still using the conventional one is a window film set-up service company called HS Auto Film. The process of processing sales data is less accurate and slower in the contrary of the developing sales data.  Computer-based window film set-up Sales Information System is built in order to make the processing data more accurate and faster.  The information system is built using Visual Basic programming language along with .NET framework technology and SQL Server database that embedded in the application itself. The making and development process of the Sales Information System is using waterfall method.  Waterfall method consists of user requirement, analysis, design, implementation, and testing. Entity Relationship Diagram, Data Flow Diagram and Flowchart are also used in the Information System design. The output of this application design is a desktop application that can help user to control the set-up of window film, manage payment bill, and manage document in accounting in faster and more accurate way. The information system can be developed later using web-based system so that the development and maintenance can be done easier.

  14. Is inflammaging an auto[innate]immunity subclinical syndrome?

    Directory of Open Access Journals (Sweden)

    Giunta Sergio

    2006-12-01

    Full Text Available Abstract The low-grade, chronic, systemic inflammatory state that characterizes the aging process (inflammaging results from late evolutive-based expression of the innate immune system. Inflammaging is characterized by the complex set of five conditions which can be described as 1. low-grade, 2. controlled, 3. asymptomatic, 4. chronic, 5. systemic, inflammatory state, and fits with the antagonistic pleiotropy theory on the evolution of aging postulating that senescence is the late deleterious effect of genes (pro-inflammatory versus anti-inflammatorythat are beneficial in early life. Evolutionary programming of the innate immune system may act via selection on these genetic traits. Here I propose that the already acquired knowledge in this field may pave the way to a new chapter in the pathophysiology of autoimmunity: the auto-innate-immunity syndromes. Indeed, differently from the well known chapter of conventional autoimmune diseases and syndromes where the main actor is the adaptive immunity, inflammaging may constitute the subclinical paradigm of a new chapter of autoimmunity, namely that arising from an autoimmune inflammatory response of the innate-immune-system, an old actor of immunity and yet a new actor of autoimmunity, also acting as a major determinant of elderly frailty and age-associated diseases.

  15. Information Processing in Auto-regulated Systems

    Directory of Open Access Journals (Sweden)

    Karl Javorszky

    2003-06-01

    Full Text Available Abstract: We present a model of information processing which is based on two concurrent ways of describing the world, where a description in one of the languages limits the possibilities for realisations in the other language. The two describing dimensions appear in our common sense as dichotomies of perspectives: subjective - objective; diversity - similarity; individual - collective. We abstract from the subjective connotations and treat the test theoretical case of an interval on which several concurrent categories can be introduced. We investigate multidimensional partitions as potential carriers of information and compare their efficiency to that of sequenced carriers. We regard the same assembly once as a contemporary collection, once as a longitudinal sequence and find promising inroads towards understanding information processing by auto-regulated systems. Information is understood to point out that what is the case from among alternatives, which could be the case. We have translated these ideas into logical operations on the set of natural numbers and have found two equivalence points on N where matches between sequential and commutative ways of presenting a state of the world can agree in a stable fashion: a flip-flop mechanism is envisioned. By following this new approach, a mathematical treatment of some poignant biomathematical problems is allowed. Also, the concepts presented in this treatise may well have relevance and applications within the information processing and the theory of language fields.

  16. Auto-interesse e incompetência

    Directory of Open Access Journals (Sweden)

    Luiz Carlos Bresser-Pereira

    2003-03-01

    Full Text Available Todas as escolas de ciências sociais têm uma hipótese comum: o auto-interesse é a variável central para explicar o comportamento humano em sociedade. Nas sociedades contemporâneas uma segunda variável está tornando-se cada vez mais relevante para explicar os resultados sociais: a incompetência técnica e emocional dos policymakers. Políticos incompetentes, que fracassam em escolher a alternativa mais consistente com seus próprios objetivos, mesmo quando interesses são neutralizados, sempre existiram. Mas, agora, que um número cada vez maior de resultados sociais dependem de políticas públicas do governo, competência tornou-se estratégica.All social science' schools have a common assumption: self-interest is the central variable explaining human behavior in society. In contemporary societies a second variable is turning increasingly relevant when one is willing to explain social outcomes: policymakers' technical and emotional incompetence. Incompetence policymakers, who fail to choose the alternative more consistent with their own objectives, even when interests were neutralized, always existed. But now, that an increasing number of social outcomes are dependent on government policy, competence has turned strategic.

  17. AutoFib2: small fibers

    Science.gov (United States)

    Goodsell, Stephen J.; Blanken, Maarten F.; Corradi, Romano; Dee, Kevin M.; Jolley, P. D.

    2003-03-01

    In July 2001, AutoFib-2 (AF2), the prime focus robotic fiber positioner for the Isaac Newton Group's (ING) 4.2m William Hershel Telescope (WHT) had its new Small Fiber Module (SFM) successfully commissioned. The new SFM contains 150 science fibers and 10 fiducial bundles. Each science fiber has a diameter of 90 μm, which corresponds to 1.6 arcsec in the sky. The continuous science fibers are fed into the Nasmyth platform Wide Field Fiber Optic Spectrograph (WYFFOS). Each fiducial bundle, 450 μm in diameter, contains 10,000 coherent fibers providing a rough imaging capability over an 8 arcsec round field. This paper looks at the reasons for developing this module, examines its mechanical design, describes its new science and fiducial fibers, looks at the fiber alignment techniques used, explains the new guiding system and briefly discusses changes in the AF2 control system. It continues to reveal the results of some fiber characterization experiments performed on sky and gives an example of a recent science run. The paper concludes with a section that lists planned AF2 enhancements.

  18. AutoCategorization for Customized Knowledge Portals Project

    Data.gov (United States)

    National Aeronautics and Space Administration — An AutoCategorizing Knowledge Management Engine ("AKM") will automate key capabilities for both human-human and human-agent collaboration tools in aerospace...

  19. The US Auto Industry in the 1990s

    National Research Council Canada - National Science Library

    Wong, David

    1990-01-01

      The recent slump in US automobile sales is primarily a cyclical phenomenon resulting from a combination of slower economic growth, more restrictive terms of auto loans, and the payback to a sustained...

  20. A Moment in the Auto/biographical Enterprise | Jansen | Current ...

    African Journals Online (AJOL)

    Abstract. Judith Lütge Coullie, Stephan Meyer, Thengani H Ngwenya and Thomas Olver (eds). (2006) Selves in Question: Interviews on Southern African Auto/biography. Honolulu: University of Hawai'i Press.

  1. Gender-Role Stereotyping among Auto-Artisans in Ghana | Edjah ...

    African Journals Online (AJOL)

    It is for this reason that the researchers examined the factors that contribute towards the choice of auto-work by male and female auto-artisans. It is also to find out the appropriateness of the choice of auto-work to their sex. Data was obtained from 350 auto-artisans in three major workshops in Ghana, namely: Siwudu(Cape ...

  2. Synthesis and luminescence in sol–gel auto-combustion ...

    Indian Academy of Sciences (India)

    2017-11-14

    Nov 14, 2017 ... Abstract. Undoped and Eu-doped CaSnO3 nanopowders were prepared by a facile sol–gel auto-combustion method calcined at 800 ... were published, synthesis of CaSnO3 through a sol–gel auto- combustion method is ... parent solutions were poured into silica crucibles and allowed to gel in an oven at ...

  3. Auto-immune encefalitis in de psychiatrische praktijk

    OpenAIRE

    de Witte, L; Kromkamp, M; Schoenmaker, N; van Mierlo, H C; Martinez-Martínez, P; Palmen, S J M; Sommer, I E C

    2015-01-01

    BACKGROUND: Our knowledge about auto-immune limbic encephalitis is increasing rapidly and it is now evident that patients with this disease can present with psychiatric symptoms. AIM: To propose practical guidelines for the recognition and diagnosis of an underlying auto-immune limbic encephalitis in patients with acute psychiatric symptoms. METHOD: We studied recent reviews on the topic and had discussions with psychiatrists, a neurologist and a neuroimmunologist in order to reach consensus....

  4. Regulatory T-cell vaccination independent of auto-antigen

    OpenAIRE

    Pascual, David W.; Yang, Xinghong; Holderness, Kathryn; Jun, SangMu; Maddaloni, Massimo; Kochetkova, Irina

    2014-01-01

    To date, efforts to treat autoimmune diseases have primarily focused on the disease symptoms rather than on the cause of the disease. In large part, this is attributed to not knowing the responsible auto-antigens (auto-Ags) for driving the self-reactivity coupled with the poor success of treating autoimmune diseases using oral tolerance methods. Nonetheless, if tolerogenic approaches or methods that stimulate regulatory T (Treg) cells can be devised, these could subdue autoimmune diseases. To...

  5. Analysis of Air Traffic Track Data with the AutoBayes Synthesis System

    Science.gov (United States)

    Schumann, Johann Martin Philip; Cate, Karen; Lee, Alan G.

    2010-01-01

    The Next Generation Air Traffic System (NGATS) is aiming to provide substantial computer support for the air traffic controllers. Algorithms for the accurate prediction of aircraft movements are of central importance for such software systems but trajectory prediction has to work reliably in the presence of unknown parameters and uncertainties. We are using the AutoBayes program synthesis system to generate customized data analysis algorithms that process large sets of aircraft radar track data in order to estimate parameters and uncertainties. In this paper, we present, how the tasks of finding structure in track data, estimation of important parameters in climb trajectories, and the detection of continuous descent approaches can be accomplished with compact task-specific AutoBayes specifications. We present an overview of the AutoBayes architecture and describe, how its schema-based approach generates customized analysis algorithms, documented C/C++ code, and detailed mathematical derivations. Results of experiments with actual air traffic control data are discussed.

  6. Schistosome infection intensity is inversely related to auto-reactive antibody levels.

    Directory of Open Access Journals (Sweden)

    Francisca Mutapi

    Full Text Available In animal experimental models, parasitic helminth infections can protect the host from auto-immune diseases. We conducted a population-scale human study investigating the relationship between helminth parasitism and auto-reactive antibodies and the subsequent effect of anti-helminthic treatment on this relationship. Levels of antinuclear antibodies (ANA and plasma IL-10 were measured by enzyme linked immunosorbent assay in 613 Zimbabweans (aged 2-86 years naturally exposed to the blood fluke Schistosoma haematobium. ANA levels were related to schistosome infection intensity and systemic IL-10 levels. All participants were offered treatment with the anti-helminthic drug praziquantel and 102 treated schoolchildren (5-16 years were followed up 6 months post-antihelminthic treatment. ANA levels were inversely associated with current infection intensity but were independent of host age, sex and HIV status. Furthermore, after allowing for the confounding effects of schistosome infection intensity, ANA levels were inversely associated with systemic levels of IL-10. ANA levels increased significantly 6 months after anti-helminthic treatment. Our study shows that ANA levels are attenuated in helminth-infected humans and that anti-helminthic treatment of helminth-infected people can significantly increase ANA levels. The implications of these findings are relevant for understanding both the aetiology of immune disorders mediated by auto-reactive antibodies and in predicting the long-term consequences of large-scale schistosomiasis control programs.

  7. The Potential of AutoClass as an Asteroidal Data Mining Tool

    Science.gov (United States)

    Walker, Matthew; Ziffer, J.; Harvell, T.; Fernandez, Y. R.; Campins, H.

    2011-05-01

    AutoClass-C, an artificial intelligence program designed to classify large data sets, was developed by NASA to classify stars based upon their infrared colors. Wanting to investigate its ability to classify asteroidal data, we conducted a preliminary test to determine if it could accurately reproduce the Tholen taxonomy using the data from the Eight Color Asteroid Survey (ECAS). For our initial test, we limited ourselves to those asteroids belonging to S, C, or X classes, and to asteroids with a color difference error of less than +/- 0.05 magnitudes. Of those 406 asteroids, AutoClass was able to confidently classify 85%: identifying the remaining asteroids as belonging to more than one class. Of the 346 asteroids that AutoClass classified, all but 3 (group associated with the other X types (which had only one rogue B type in with its other 49 X-types). Autoclass classified the remaining classes with a high accuracy: placing one A and one CU type in with an otherwise perfect S group; placing three P type and one T type in an otherwise perfect D group; and placing the four remaining asteroids (V, A, R, and Q) into a class together.

  8. Three Dimensional Magneto-Hydrodynamics Simulations of Auto-Magnetizing Imploding Liners for ICF

    Science.gov (United States)

    Woolstrum, Jeff; Jennings, Chris; Shipley, Gabriel; Awe, Thomas; Slutz, Stephen; Jordan, Nicholas; Lau, Yy; Peterson, Kyle; McBride, Ryan

    2017-10-01

    AutoMag is a potential next step in the magnetized liner inertial fusion (MagLIF) program. In standard MagLIF, external coils are used to magnetize deuterium gas inside a metal cylindrical liner, which is imploded by the Z-machine at Sandia National Laboratories. In AutoMag, helical slots are cut into the liner and filled with dielectric insulator to form a solenoid, producing an axial magnetic field from the drive current and removing the need for external field coils. Alternatively with external field coils, AutoMag could produce a field-reversed configuration inside the liner. Recent work at Sandia has found that the breakdown of the dielectric material corresponds to the geometry of the liner/dielectric. We explore this finding in 3D resistive-MHD simulations, modeling geometries relevant to both the 20-MA Z facility, and to the 1-MA MAIZE facility at the University of Michigan. Sandia National Laboratories is a multimission laboratory managed and operated by National Technology and Engineering Solutions of Sandia LLC, a wholly owned subsidiary of Honeywell International Inc. for the U.S. DoE's NNSA under contract DE-NA0003525.

  9. AutoFACT: An Automatic Functional Annotation and Classification Tool

    Directory of Open Access Journals (Sweden)

    Lang B Franz

    2005-06-01

    Full Text Available Abstract Background Assignment of function to new molecular sequence data is an essential step in genomics projects. The usual process involves similarity searches of a given sequence against one or more databases, an arduous process for large datasets. Results We present AutoFACT, a fully automated and customizable annotation tool that assigns biologically informative functions to a sequence. Key features of this tool are that it (1 analyzes nucleotide and protein sequence data; (2 determines the most informative functional description by combining multiple BLAST reports from several user-selected databases; (3 assigns putative metabolic pathways, functional classes, enzyme classes, GeneOntology terms and locus names; and (4 generates output in HTML, text and GFF formats for the user's convenience. We have compared AutoFACT to four well-established annotation pipelines. The error rate of functional annotation is estimated to be only between 1–2%. Comparison of AutoFACT to the traditional top-BLAST-hit annotation method shows that our procedure increases the number of functionally informative annotations by approximately 50%. Conclusion AutoFACT will serve as a useful annotation tool for smaller sequencing groups lacking dedicated bioinformatics staff. It is implemented in PERL and runs on LINUX/UNIX platforms. AutoFACT is available at http://megasun.bch.umontreal.ca/Software/AutoFACT.htm.

  10. [Oral diseases in auto-immune polyendocrine syndrome type 1].

    Science.gov (United States)

    Proust-Lemoine, Emmanuelle; Guyot, Sylvie

    2017-09-01

    Auto-immune polyendocrine syndrome type 1 (APS1) also called Auto-immune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED) is a rare monogenic childhood-onset auto-immune disease. This autosomal recessive disorder is caused by mutations in the auto-immune regulator (AIRE) gene, and leads to autoimmunity targeting peripheral tissues. There is a wide variability in clinical phenotypes in patients with APSI, with auto-immune endocrine and non-endocrine disorders, and chronic mucocutaneous candidiasis. These patients suffer from oral diseases such as dental enamel hypoplasia and candidiasis. Both are frequently described, and in recent series, enamel hypoplasia and candidiasis are even the most frequent components of APS1 together with hypoparathyroidism. Both often occur during childhood (before 5 years old for canrdidiasis, and before 15 years old for enamel hypoplasia). Oral candidiasis is recurrent all life long, could become resistant to azole antifungal after years of treatment, and be carcinogenic, leading to severe oral squamous cell carcinoma. Oral components of APS1 should be diagnosed and rigorously treated. Dental enamel hypoplasia and/or recurrent oral candidiasis in association with auto-immune diseases in a young child should prompt APS1 diagnosis. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  11. Auto-phosphorylation Represses Protein Kinase R Activity.

    Science.gov (United States)

    Wang, Die; de Weerd, Nicole A; Willard, Belinda; Polekhina, Galina; Williams, Bryan R G; Sadler, Anthony J

    2017-03-10

    The central role of protein kinases in controlling disease processes has spurred efforts to develop pharmaceutical regulators of their activity. A rational strategy to achieve this end is to determine intrinsic auto-regulatory processes, then selectively target these different states of kinases to repress their activation. Here we investigate auto-regulation of the innate immune effector protein kinase R, which phosphorylates the eukaryotic initiation factor 2α to inhibit global protein translation. We demonstrate that protein kinase R activity is controlled by auto-inhibition via an intra-molecular interaction. Part of this mechanism of control had previously been reported, but was then controverted. We account for the discrepancy and extend our understanding of the auto-inhibitory mechanism by identifying that auto-inhibition is paradoxically instigated by incipient auto-phosphorylation. Phosphor-residues at the amino-terminus instigate an intra-molecular interaction that enlists both of the N-terminal RNA-binding motifs of the protein with separate surfaces of the C-terminal kinase domain, to co-operatively inhibit kinase activation. These findings identify an innovative mechanism to control kinase activity, providing insight for strategies to better regulate kinase activity.

  12. Auto/ethnography: A Transformative Research Paradigm

    Directory of Open Access Journals (Sweden)

    Sadruddin Bahadur Qutoshi

    2015-12-01

    Full Text Available This paper aims to address the key question, ‘How far autoethnography contributes towards enriching the field of transformative learning?’ Using my lived experiences as a teacher educator/autoethnographer/researcher and contextualizing self/others within a particular socio-pedagogical life courses I build the basis through addressing questions: Why auto/ethnography is one of the most suitable spaces for transformative researchers and to what extent it serves the agenda of envisioning a transformative teacher education. To achieve this objective I use autobiographies, stories, reflections and poems etc. as narratives with multiple logics and genres; pictography as art-based expression; and ethnography as methodological space within multiparadigmatic design space. In so doing autoethnographer has to delve into whole process of research along a continuum of self and beyond within a particular sociocultural context to understand the phenomena at deeper level of consciousness. This transformative paradigm holds a strong basis in the process of research as: re/reading, re/viewing, critically reflecting on self/others, re/writing for meaning making and developing a subjective understanding of phenomena under exploration. This process of research is found to be an innovative way of knowing through ‘interpreting and constructing (Luitel, 2009within Interpretivism, critically thinking and reflecting within Criticalism, and adding both ‘pluralism and playfulness’ (Taylor, 2013 within Postmodernism. In so doing it raises awareness, develops consciousness and improves capacities constantly that ultimately alters our way of seeing and being in the world differently- a paradigm shift in self/others. It is found to be highly rigorous, dialectically eloquent, dialogically rigorous, critically reflective, consciously awakening, and innovative critical discourse that greatly contributes to transform researcher/s. Therefore, it seems illustrious for

  13. Auto-context Convolutional Neural Network (Auto-Net) for Brain Extraction in Magnetic Resonance Imaging.

    Science.gov (United States)

    Salehi, Seyed Sadegh Mohseni; Erdogmus, Deniz; Gholipour, Ali

    2017-06-28

    Brain extraction or whole brain segmentation is an important first step in many of the neuroimage analysis pipelines. The accuracy and robustness of brain extraction, therefore, is crucial for the accuracy of the entire brain analysis process. State-of-the-art brain extraction techniques rely heavily on the accuracy of alignment or registration between brain atlases and query brain anatomy, and/or make assumptions about the image geometry; therefore have limited success when these assumptions do not hold or image registration fails. With the aim of designing an accurate, learning-based, geometry-independent and registration-free brain extraction tool in this study, we present a technique based on an auto-context convolutional neural network (CNN), in which intrinsic local and global image features are learned through 2D patches of different window sizes. We consider two different architectures: 1) a voxelwise approach based on three parallel 2D convolutional pathways for three different directions (axial, coronal, and sagittal) that implicitly learn 3D image information without the need for computationally expensive 3D convolutions, and 2) a fully convolutional network based on the U-net architecture. Posterior probability maps generated by the networks are used iteratively as context information along with the original image patches to learn the local shape and connectedness of the brain to extract it from non-brain tissue. The brain extraction results we have obtained from our CNNs are superior to the recently reported results in the literature on two publicly available benchmark datasets, namely LPBA40 and OASIS, in which we obtained Dice overlap coefficients of 97.73% and 97.62%, respectively. Significant improvement was achieved via our auto-context algorithm. Furthermore, we evaluated the performance of our algorithm in the challenging problem of extracting arbitrarily-oriented fetal brains in reconstructed fetal brain magnetic resonance imaging (MRI

  14. Cirios, trompetas y altares : el auto de fe como fiesta

    Directory of Open Access Journals (Sweden)

    Doris Moreno Martínez

    1997-01-01

    Full Text Available El análisis del auto de fe en su vertiente festiva nos permite superar la vieja polémica de la historiografía liberal y la historiografia conservadora, en torno a la popularidad/repulsión social de la Inquisición. Trascendiendo las visiones unidireccionales, se intenta aprender el auto de fe general desde una perspectiva global; se integran las vertientes jurídica, religiosa y social a través de algunos de los múltiples ingredientes del auto: sensitivos (luz, colores, sonidos..., sociales (participación activa de artesanos, familiares y asistentes... y simbólicos (orden preeminencial en las procesiones y en los tablados, juramentos..., para configurar el auto de fe como una fiesta compleja. poliédrica. En el auto de fe la Iglesia y el Estado tantas veces enfrentados, mostraban sus respectivos poderes concertados, con toda la capacidad intimidatoría de una simbología muy funcional y efectiva, y los componentes mórbidos de identificación personal del mal y la escenificación dramática.The analysis of the auto de fe on its festive side allows us to overecome the old discussion between the liberal histórical view and the conservative view that surrounds the social popularity/repulsion of the Inquisition. Overcoming the narrow visión we try to understand a global perspective; we intégrate the juridical, religious and social aspects through some of the many ingredients of the auto de fe: sensory (light, colours, sounds..., social (active participation of artisans, families and people present... and symbolical (order of rank in processions on stages and oath taking.... All those aspects combine to make the auto de fe a very complex and many sided festivity. In the auto de fe, the Church and the State, many times oppossed to one another, showed that their respective powers were united, with all the intimidating power of a very effective and functional symbolism and the morbid components of a personal identification of evil and the

  15. ACCTuner: OpenACC Auto-Tuner For Accelerated Scientific Applications

    KAUST Repository

    Alzayer, Fatemah

    2015-05-17

    We optimize parameters in OpenACC clauses for a stencil evaluation kernel executed on Graphical Processing Units (GPUs) using a variety of machine learning and optimization search algorithms, individually and in hybrid combinations, and compare execution time performance to the best possible obtained from brute force search. Several auto-tuning techniques – historic learning, random walk, simulated annealing, Nelder-Mead, and genetic algorithms – are evaluated over a large two-dimensional parameter space not satisfactorily addressed to date by OpenACC compilers, consisting of gang size and vector length. A hybrid of historic learning and Nelder-Mead delivers the best balance of high performance and low tuning effort. GPUs are employed over an increasing range of applications due to the performance available from their large number of cores, as well as their energy efficiency. However, writing code that takes advantage of their massive fine-grained parallelism requires deep knowledge of the hardware, and is generally a complex task involving program transformation and the selection of many parameters. To improve programmer productivity, the directive-based programming model OpenACC was announced as an industry standard in 2011. Various compilers have been developed to support this model, the most notable being those by Cray, CAPS, and PGI. While the architecture and number of cores have evolved rapidly, the compilers have failed to keep up at configuring the parallel program to run most e ciently on the hardware. Following successful approaches to obtain high performance in kernels for cache-based processors using auto-tuning, we approach this compiler-hardware gap in GPUs by employing auto-tuning for the key parameters “gang” and “vector” in OpenACC clauses. We demonstrate results for a stencil evaluation kernel typical of seismic imaging over a variety of realistically sized three-dimensional grid configurations, with different truncation error orders

  16. Auto/Ethnography and the Question of Ethics

    Directory of Open Access Journals (Sweden)

    Wolff-Michael Roth

    2008-10-01

    Full Text Available Auto/ethnography has emerged as an important method in the social sciences for contributing to the project of understanding human actions and concerns. Although the name of the method includes "ethnography," auto/ethnography often is concerned exclusively with an abstract (i.e., undeveloped and abstracting understanding, and therefore the writing, of the Self rather than the writing of the "ethno." Auto/ethnography, such conceived, is a form of therapy, in the best case, and a form of narcissism and autoerotic relation, in the worst case. But because the Self exists in relation to the world, becomes in and through participation in everyday events, and because the human relation is inherently ethical, there are inherent ethical questions where the Other may come to be harmed as much as the Self. URN: urn:nbn:de:0114-fqs0901381

  17. AutoCAD electrical 2013 for electrical control designers

    CERN Document Server

    Tickoo, Sham; CADCIM Technologies

    2013-01-01

    The AutoCAD Electrical 2013 for Electrical Control Designers textbook has been written to assist the engineering students and the practicing designers learn the application of various AutoCAD Electrical tools and options for creating electrical control designs. After reading this textbook, the users will be able to create professional electrical-control drawings easily and effectively. Moreover, the users will be able to automate various control engineering tasks such as building circuits, numbering wires, creating bills of materials, and many more. The textbook takes the users across a wide spectrum of electrical control drawings through progressive examples and numerous illustrations and exercises, thereby making it an ideal guide for both the novice and the advanced users. Salient Features of the Textbook Consists of 14 chapters that are organized in a pedagogical sequence covering various tools and features of AutoCAD Electrical such as schematic drawings, parametric and non-parametric PLC modules, Circu...

  18. Auto-tuning system for NMR probe with LabView

    Science.gov (United States)

    Quen, Carmen; Mateo, Olivia; Bernal, Oscar

    2013-03-01

    Typical manual NMR-tuning method is not suitable for broadband spectra spanning several megahertz linewidths. Among the main problems encountered during manual tuning are pulse-power reproducibility, baselines, and transmission line reflections, to name a few. We present a design of an auto-tuning system using graphic programming language, LabVIEW, to minimize these problems. The program is designed to analyze the detected power signal of an antenna near the NMR probe and use this analysis to automatically tune the sample coil to match the impedance of the spectrometer (50 Ω). The tuning capacitors of the probe are controlled by a stepper motor through a LabVIEW/computer interface. Our program calculates the area of the power signal as an indicator to control the motor so disconnecting the coil to tune it through a network analyzer is unnecessary. Work supported by NSF-DMR 1105380

  19. Ping-pong auto-zero amplifier with glitch reduction

    Science.gov (United States)

    Larson, Mark R [Maple Grove, MN

    2008-01-22

    A ping-pong amplifier with reduced glitching is described. The ping-pong amplifier includes a nulling amplifier coupled to a switching network. The switching network is used to auto-zero a ping amplifier within a ping-pong amplifier. The nulling amplifier drives the output of a ping amplifier to a proper output voltage level during auto-zeroing of the ping amplifier. By being at a proper output voltage level, glitches associated with transitioning between a ping amplifier and a pong amplifier are reduced or eliminated.

  20. STUDY CONCERNING CUSTOMERS’ LOYALTY IN THE AUTO MARKET

    Directory of Open Access Journals (Sweden)

    Tudor NISTORESCU

    2013-11-01

    Full Text Available In this paper we made an analysis of the loyalty in the auto market. We selected a sample from the residents of Craiova and asked them about their intentions concerning satisfaction, repurchase and recommendation regarding their cars. We used as auto market as the base of our study, since the car industry is very attractive to customers. We documented some correlation among the three dimensions of the loyalty. At the applicative level we found out that the loyalty toward the German cars is much higher than the loyalty for the cars from other countries. Further studies are needed to investigate the complex dimensions of the loyalty in-depth.

  1. Design of programmable logic controller auto power reset circuit for FM transmitter

    Directory of Open Access Journals (Sweden)

    Adisak Pattanajakr

    2016-06-01

    Full Text Available The mono-stereo controller using audio mute clock is used at the International Broadcasting Bureau (IBB FM 106.6 MHz transmitter in Ulaan Baatar, Mongolia since 2010. The major problem of the FM broadcast station was from the frozen Programmable Logic Controller, PLC, which must be manually reset and the report by the VOA listeners. Then, the PLC auto power reset circuit is proposed and built in mono-stereo controller to monitor the operation of the PLC. The circuit is also used to restart the PLC whenever, it is frozen. The cloud router and Transmission Control Protocol/Internet Protocol (TCP/IP to Recommended Standard number 232 (RS-232 converter are used to synchronize the PLC time. From the results, this circuit can improve the transmitter availability and quality of the 24 hours/day broadcast program without affection to the listeners. The reliability of the cloud router is acceptable with low delay of data transfer via the internet connection between Thailand to Mongolia. The cloud router which the IBB leases cloud service from the provider that offers high speed internet up to 1000 Mb/s, via the remote terminal is used for the schedule program and the time synchronization of the PLC correctly. The proposed system is very stable and there is no problem of the frozen PLC whether it connects to the internet or not. Hence, the designed PLC auto power reset circuit can be used to eliminate the frozen PLC problem.

  2. CICAAR - Convolutive ICA with an Auto-Regressive Inverse Model

    DEFF Research Database (Denmark)

    Dyrholm, Mads; Hansen, Lars Kai

    2004-01-01

    We invoke an auto-regressive IIR inverse model for convolutive ICA and derive expressions for the likelihood and its gradient. We argue that optimization will give a stable inverse. When there are more sensors than sources the mixing model parameters are estimated in a second step by least squares...

  3. Bioremediation of Soil Microcosms from Auto-Mechanic Workshops ...

    African Journals Online (AJOL)

    Microbial activities are essential for the restoration of soil contaminated with hydrocarbons, their roles includes biotransformation and mineralization of petroleum products into harmless compounds. In this study eighty six soil samples from fifteen auto-mechanic workshops within Ilorin metropolis were collected. These were ...

  4. Auto-Tutorial Instruction in Entomology: Principles of Entomology (Orders).

    Science.gov (United States)

    Minnick, D. R.; Steele, K. L.

    Auto-tutorial instruction was compared to traditional lecture instruction in a university entomology course. In seven consecutive terms, undergraduate students enrolled in an introductory entomology course were divided into two groups: Group I received only lecture instruction on insect orders, while Group II was dismissed for three consecutive…

  5. Inflation - Growth Nexus in Ethiopia: Evidence from Threshold Auto ...

    African Journals Online (AJOL)

    Optiplex 7010 Pro

    Inflation - Growth Nexus in Ethiopia: Evidence from Threshold Auto Regressive Model. 1. Ashagrie Demile. 2. Abstract. Achieving high economic growth with stable and low inflation level has long been the macroeconomic policy objective of Ethiopia. The Ethiopian economy, however, has gone through different paths of ...

  6. "O auto-retrato em crianças institucionalizadas"

    Directory of Open Access Journals (Sweden)

    Sonia Regina Pasian

    1999-12-01

    Full Text Available O presente trabalho estudou, por meio de desenhos de auto-retrato, a imagem corporal e o auto-conceito de crianças institucionalizadas (n = 37 e não institucionalizadas (n = 32, do sexo masculino e com idade entre sete e treze anos. As crianças dos dois grupos foram pareadas em termos etários e de escolaridade. Sua produção gráfica foi avaliada pela Escala de Indicadores Emocionais de Koppitz. Os resultados apontaram diferenças significativas entre os dois grupos, evidenciando que os meninos institucionalizados apresentaram maior número de indicadores emocionais em seus auto-retratos. A idade não pareceu fator decisivo nestas diferenças. O tempo de vida na instituição sinalizou-se fator relevante nos resultados, favorecendo aquisição de elementos propiciadores de uma imagem corporal mais integrada, comparativamente àqueles meninos institucionalizados há pouco tempo. As evidências sugerem que a institucionalização causa impacto emocional negativo na criança, porém a qualidade das experiências neste contexto é que pareceu determinante para cristalizar ou não processos de auto-desvalorização.

  7. Synthesis and luminescence in sol–gel auto-combustion ...

    Indian Academy of Sciences (India)

    gel auto-combustion methodcalcined at 800 ∘ C for 1 h. The samples are found to be well-crystallized pure orthorhombic CaSnO 3 structure. Photoluminescence (PL) measurements indicated that the undoped sample exhibits a broad blue ...

  8. Auto-correlation analysis of ocean surface wind vectors

    Indian Academy of Sciences (India)

    The nature of the inherent temporal variability of surface winds is analyzed by comparison of winds obtained through different measurement methods. In this work, an auto-correlation analysis of a time series data of surface winds measured in situ by a deep water buoy in the Indian Ocean has been carried out. Hourly time ...

  9. Dispersion effect and auto-reconditioning performance of nanometer ...

    Indian Academy of Sciences (India)

    This paper reported on dispersion effect and dispersing techniques of nanometer WS2 particles in the green lubricant concocted by us. And it also researched on auto-reconditioning performance of nanometer WS2 particles to the abrasive surfaces of steel ball from four-ball tribology test and piston ring from engine ...

  10. Measurement of antiacetylcholine receptor auto-antibodies in ...

    African Journals Online (AJOL)

    Two different acetylcholine receptor (AChR) preparations derived from amputated human muscle (AChRAMP) and from the human rhabdomyosarcoma cell line TE671 (AChRTE67,) were compared in radio-immunoprecipitation assays for the detection of AChR auto-antibodies in serum specimens from 20 patients with ...

  11. Careers in Auto Racing: Work in the Fast Lane

    Science.gov (United States)

    Lawhorn, William

    2009-01-01

    Long before most people had seen an automobile, thrill-seekers across the globe were driving cars competitively. The speed of racecars has accelerated steadily, as has the popularity of the sport. In public opinion polls of sports popularity, in fact, auto racing consistently finishes near the top. Racecar drivers may be the star of their event,…

  12. The Global Product: Internationalization of the Auto Industry.

    Science.gov (United States)

    Stanford Univ., CA. Stanford Program on International and Cross Cultural Education.

    This secondary level unit, designed for use in a social studies or introductory economics course, has students participate in decision-making activities about global auto production. Although Japan-United States interaction is emphasized, the concepts, terms and activities employed in the unit apply to other countries as well. The unit includes 11…

  13. Auto-calibration of Systematic Odometry Errors in Mobile Robots

    DEFF Research Database (Denmark)

    Bak, Martin; Larsen, Thomas Dall; Andersen, Nils Axel

    1999-01-01

    This paper describes the phenomenon of systematic errors in odometry models in mobile robots and looks at various ways of avoiding it by means of auto-calibration. The systematic errors considered are incorrect knowledge of the wheel base and the gains from encoder readings to wheel displacement...... and experiments on a mobile robot....

  14. Sex identification of Nigerian indigenous chicks using Auto-sexing ...

    African Journals Online (AJOL)

    Sexing has been a challenging task in Nigerian indigenous chickens due to the monomorphism of chicks which makes it impossible to distinguish the male from the female until eight weeks. . Therefore, this study was carried out to determine the sex of Nigerian indigenous chicks using the common auto-sexing methods.

  15. Genetic aspects of auto-immune profiles of healthy chickens.

    Science.gov (United States)

    Parmentier, Henk K; van der Vaart, Priscilla S; Nieuwland, Mike G B; Savelkoul, Huub F J

    2017-09-01

    Auto-antibody profiles binding liver antigens differed between chicken lines divergently selected for specific antibody responses to SRBC, and were affected by ageing suggesting both genetic and environmental effects. Presence and levels of IgM and IgG antibodies binding chicken liver cell lysate (CLL) fragments in plasma at 5 weeks of age from 10 individual full sibs and their parents from 5 Hsrbc and 5 Lsrbc line families was studied to reveal genetic relations. Non-genetic maternal effects were studied by comparing auto-antibody profiles of 36 weeks old hens from 2 other unrelated lines with the profiles from their chicks at hatch. IgM and IgG antibodies from parents and progeny from both Hsrbc and Lsrbc lines bound CLL fragments. Significant line and generation differences and their interactions were found for both isotypes. Higher staining of CLL fragments was usually found for Hsrbc line birds. Lines were clustered by auto-antibody profiles, but staining by birds of both lines in both generations was very individual for IgG and IgM. The current data with full sibs therefore not supported a genetic basis for auto-antibody profiles. IgG but not IgM auto-antibody profiles of chicks correlated with maternal auto-antibody profiles. The results suggest that the auto-antibody repertoire of healthy chickens is largely stochastically initiated and may be affected by environmental challenges during ageing, but genetic mechanisms may underlie staining intensity of individual bound CLL fragments. The present results suggest that identification of fragments or profiles to be used at early age for genetic selection for health traits is not feasible yet. Secondly, the IgM profile of neonatal chickens seems non-organised independent of the maternal profile, but the neonatal IgG profile is much more related with the maternal profile. Consequences of these findings for disease susceptibility or breeding for optimal health are discussed. Copyright © 2017 Elsevier Ltd. All

  16. Assessment of the Use of AutoCAD in Mechanical Engineering Technical Drawing Education

    OpenAIRE

    Akyürek, Turgut

    2017-01-01

    AutoCAD is one of the widely used software tools in engineering education. In this study, ageneral assessment of AutoCAD for the usage in the mechanical engineering technical drawing educationis made. AutoCAD is assessed in terms of the fulfilment of the requirements defined for the main twotechnical drawing courses. AutoCAD is assessed in terms of its capability in meeting the requirements ofthe technical drawing courses.

  17. AutoSite: an automated approach for pseudo-ligands prediction—from ligand-binding sites identification to predicting key ligand atoms

    Science.gov (United States)

    Ravindranath, Pradeep Anand; Sanner, Michel F.

    2016-01-01

    Motivation: The identification of ligand-binding sites from a protein structure facilitates computational drug design and optimization, and protein function assignment. We introduce AutoSite: an efficient software tool for identifying ligand-binding sites and predicting pseudo ligand corresponding to each binding site identified. Binding sites are reported as clusters of 3D points called fills in which every point is labelled as hydrophobic or as hydrogen bond donor or acceptor. From these fills AutoSite derives feature points: a set of putative positions of hydrophobic-, and hydrogen-bond forming ligand atoms. Results: We show that AutoSite identifies ligand-binding sites with higher accuracy than other leading methods, and produces fills that better matches the ligand shape and properties, than the fills obtained with a software program with similar capabilities, AutoLigand. In addition, we demonstrate that for the Astex Diverse Set, the feature points identify 79% of hydrophobic ligand atoms, and 81% and 62% of the hydrogen acceptor and donor hydrogen ligand atoms interacting with the receptor, and predict 81.2% of water molecules mediating interactions between ligand and receptor. Finally, we illustrate potential uses of the predicted feature points in the context of lead optimization in drug discovery projects. Availability and Implementation: http://adfr.scripps.edu/AutoDockFR/autosite.html Contact: sanner@scripps.edu Supplementary information: Supplementary data are available at Bioinformatics online. PMID:27354702

  18. Collective Mind: Towards Practical and Collaborative Auto-Tuning

    Directory of Open Access Journals (Sweden)

    Grigori Fursin

    2014-01-01

    Full Text Available Empirical auto-tuning and machine learning techniques have been showing high potential to improve execution time, power consumption, code size, reliability and other important metrics of various applications for more than two decades. However, they are still far from widespread production use due to lack of native support for auto-tuning in an ever changing and complex software and hardware stack, large and multi-dimensional optimization spaces, excessively long exploration times, and lack of unified mechanisms for preserving and sharing of optimization knowledge and research material. We present a possible collaborative approach to solve above problems using Collective Mind knowledge management system. In contrast with previous cTuning framework, this modular infrastructure allows to preserve and share through the Internet the whole auto-tuning setups with all related artifacts and their software and hardware dependencies besides just performance data. It also allows to gradually structure, systematize and describe all available research material including tools, benchmarks, data sets, search strategies and machine learning models. Researchers can take advantage of shared components and data with extensible meta-description to quickly and collaboratively validate and improve existing auto-tuning and benchmarking techniques or prototype new ones. The community can now gradually learn and improve complex behavior of all existing computer systems while exposing behavior anomalies or model mispredictions to an interdisciplinary community in a reproducible way for further analysis. We present several practical, collaborative and model-driven auto-tuning scenarios. We also decided to release all material at c-mind.org/repo to set up an example for a collaborative and reproducible research as well as our new publication model in computer engineering where experimental results are continuously shared and validated by the community.

  19. The impacts of auto-mechanic workshops on soil and groundwater ...

    African Journals Online (AJOL)

    The extents of groundwater and soil pollution arising from auto-mechanic activities from auto-mechanic workshops at Ibadan metropolis were examined. Groundwater and top soil samples from auto-mechanic villages and control site were collected fortnightly over a period of two months and analysed for both ...

  20. 47 CFR 80.307 - Compulsory use of radiotelegraph auto alarm.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Compulsory use of radiotelegraph auto alarm. 80.307 Section 80.307 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL... Safety Watches § 80.307 Compulsory use of radiotelegraph auto alarm. The radiotelegraph auto alarm...

  1. 75 FR 65524 - United Auto Workers Local 1999, Oklahoma City, OK; Notice of Negative Determination Regarding...

    Science.gov (United States)

    2010-10-25

    ... Employment and Training Administration United Auto Workers Local 1999, Oklahoma City, OK; Notice of Negative... Trade Adjustment Assistance (TAA), applicable to workers and former workers of United Auto Workers Local... petition filed on behalf of workers at United Auto Workers Local 1999, Oklahoma City, Oklahoma, was based...

  2. 75 FR 24753 - The Walker Auto Group, Inc., Miamisburg, OH; Notice of Negative Determination Regarding...

    Science.gov (United States)

    2010-05-05

    ... Employment and Training Administration The Walker Auto Group, Inc., Miamisburg, OH; Notice of Negative... TAA petition filed on behalf of workers at The Walker Auto Group, Inc., Miamisburg, Ohio, was based on... Walker Auto Group, Inc., Miamisburg, Ohio, supplies a service (sales and service of Pontiac automobiles...

  3. AutoTutor and Family: A Review of 17 Years of Natural Language Tutoring

    Science.gov (United States)

    Nye, Benjamin D.; Graesser, Arthur C.; Hu, Xiangen

    2014-01-01

    AutoTutor is a natural language tutoring system that has produced learning gains across multiple domains (e.g., computer literacy, physics, critical thinking). In this paper, we review the development, key research findings, and systems that have evolved from AutoTutor. First, the rationale for developing AutoTutor is outlined and the advantages…

  4. REFLEXÕES ACERCA DOS CONCEITOS AUTO-CUIDADO E COMPETÊNCIA/PODER PARA O AUTO-CUIDADO

    Directory of Open Access Journals (Sweden)

    Eloita Pereira Neves

    Full Text Available Neste trabalho a autora apresenta alguns aspectos da teoria de auto-cuidado de Orem e discute sua visão sobre poder/competência para abordagem cognitiva, baseada na teoria de desenvolvimento cognitivo de Perry. Alguns estudos que dão suporte a sua abordagem são revistas.

  5. Auto-Interviewing, Auto-Ethnography and Critical Incident Methodology for Eliciting a Self-Conceptualised Worldview

    Directory of Open Access Journals (Sweden)

    Béatrice Boufoy-Bastick

    2004-01-01

    Full Text Available Knowing oneself has been an age-old humanistic concern for many western and oriental philosophers. The same concern is now shared by modern psychologists and anthropologists who seek to understand the "self" and others by eluci­dating their worldviews. This paper presents an auto-anthropological methodology which can ef­fec­tively elucidate one's worldview. This intro­spective qualitative methodology uses integratively three methodological processes, namely auto-inter­viewing, auto-ethnography and critical incident technique to elicit baseline cultural data. The paper reports on how this methodology was used to elicit my current worldview. It first explains how emic data were educed and rendered in emo­tionally enhanced narratives, which were then deconstructed to elicit the major recurring themes in the etic interpretive content analysis. To illus­trate this auto-anthropological methodology, two cultural life events have been used: a critical incident in Singapore and a consciousness raising process in Fiji. The first event revealed my own education ideology while the second made me realise my mitigated support for cultural diversity. URN: urn:nbn:de:0114-fqs0401371

  6. Introduction to Programming in LISP.

    Science.gov (United States)

    King, Margaret

    The first section of this course on programming introduces LISP as a programming language designed to do symbol manipulation, with consequent prevalence in auto-instructional (AI) work. A programming language specifies in its description a number of primitive operations which the computer knows how to perform. An algorithm is the set of…

  7. Auto Draw from Excel Input Files

    Science.gov (United States)

    Strauss, Karl F.; Goullioud, Renaud; Cox, Brian; Grimes, James M.

    2011-01-01

    The design process often involves the use of Excel files during project development. To facilitate communications of the information in the Excel files, drawings are often generated. During the design process, the Excel files are updated often to reflect new input. The problem is that the drawings often lag the updates, often leading to confusion of the current state of the design. The use of this program allows visualization of complex data in a format that is more easily understandable than pages of numbers. Because the graphical output can be updated automatically, the manual labor of diagram drawing can be eliminated. The more frequent update of system diagrams can reduce confusion and reduce errors and is likely to uncover symmetric problems earlier in the design cycle, thus reducing rework and redesign.

  8. A relação entre auto-estima, auto imagem e qualidade de vida em idosos participantes de uma oficina de inclusão digital

    OpenAIRE

    Fraquelli, Ângela Aita

    2008-01-01

    Introdução: A educação permanente de idosos ativos e integrados na sociedade – sob o ponto de vista dos níveis de auto-estima, auto-imagem e qualidade de vida, pode contribuir para que o indivíduo alcance uma velhice bem-sucedida. Objetivos: O presente estudo teve como objetivo avaliar os níveis de auto-estima, auto-imagem e qualidade de vida em um grupo de idosos participantes das oficinas de inclusão digital do Projeto Potencialidade da Pontifícia Universidade Católica do Rio Grande do Sul ...

  9. The AutoProof Verifier: Usability by Non-Experts and on Standard Code

    Directory of Open Access Journals (Sweden)

    Carlo A. Furia

    2015-08-01

    Full Text Available Formal verification tools are often developed by experts for experts; as a result, their usability by programmers with little formal methods experience may be severely limited. In this paper, we discuss this general phenomenon with reference to AutoProof: a tool that can verify the full functional correctness of object-oriented software. In particular, we present our experiences of using AutoProof in two contrasting contexts representative of non-expert usage. First, we discuss its usability by students in a graduate course on software verification, who were tasked with verifying implementations of various sorting algorithms. Second, we evaluate its usability in verifying code developed for programming assignments of an undergraduate course. The first scenario represents usability by serious non-experts; the second represents usability on "standard code", developed without full functional verification in mind. We report our experiences and lessons learnt, from which we derive some general suggestions for furthering the development of verification tools with respect to improving their usability.

  10. Occupational noise-induced hearing loss in auto part factory workers in welding units in Thailand.

    Science.gov (United States)

    Sriopas, Apiradee; Chapman, Robert S; Sutammasa, Saravudh; Siriwong, Wattasit

    2017-01-24

    Most workers in auto part factories in Thailand are usually exposed to excessive noise in their workplace. This study aimed to assess the level of occupational noise-induced hearing loss and investigate risk factors causing hearing loss in auto part factory workers in the welding units in Thailand. This was a cross-sectional study. One hundred eighty subjects were recruited from 356 workers in the welding unit of three factories. Sixty eligible subjects in each factory were selected by systemic random sampling. The subjects were interviewed using a face-to-face questionnaire. Noise exposure levels and audiograms were measured by a noise dosimeter and an audiometer, respectively. The findings confirmed that noise exposure levels of 86-90 dB (A) and exceeding 90 dB (A) significantly increased the risk of hearing loss in either ear. A noise exposure level exceeding 90 dB (A) significantly increased the prevalence of hearing loss in both ears. Regarding, a 10-pack-year smoking history increased the prevalence of hearing loss in either ear or both ears. In addition, subjects with employment duration exceeding 10 years significantly developed hearing loss in either ear. The engineering control or personal control by wearing hearing protection device should be used to decrease noise exposure levels lower than 85 dB (A) for 8 h. Moreover, if the exposure level reaches 85 dB (A) for 8 h, the employer needs to implement a hearing conservation program in the workplace.

  11. AUTO_DERIV: Tool for automatic differentiation of a Fortran code

    Science.gov (United States)

    Stamatiadis, S.; Farantos, S. C.

    2010-10-01

    AUTO_DERIV is a module comprised of a set of FORTRAN 95 procedures which can be used to calculate the first and second partial derivatives (mixed or not) of any continuous function with many independent variables. The mathematical function should be expressed as one or more FORTRAN 77/90/95 procedures. A new type of variables is defined and the overloading mechanism of functions and operators provided by the FORTRAN 95 language is extensively used to define the differentiation rules. Proper (standard complying) handling of floating-point exceptions is provided by using the IEEE_EXCEPTIONS intrinsic module (Technical Report 15580, incorporated in FORTRAN 2003). New version program summaryProgram title: AUTO_DERIV Catalogue identifier: ADLS_v2_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADLS_v2_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 2963 No. of bytes in distributed program, including test data, etc.: 10 314 Distribution format: tar.gz Programming language: Fortran 95 + (optionally) TR-15580 (Floating-point exception handling) Computer: all platforms with a Fortran 95 compiler Operating system: Linux, Windows, MacOS Classification: 4.12, 6.2 Catalogue identifier of previous version: ADLS_v1_0 Journal reference of previous version: Comput. Phys. Comm. 127 (2000) 343 Does the new version supersede the previous version?: Yes Nature of problem: The need to calculate accurate derivatives of a multivariate function frequently arises in computational physics and chemistry. The most versatile approach to evaluate them by a computer, automatically and to machine precision, is via user-defined types and operator overloading. AUTO_DERIV is a Fortran 95 implementation of them, designed to evaluate the first and second derivatives of a function of many variables

  12. Lean Manufacturing Auto Cluster at Chennai

    Science.gov (United States)

    Bhaskaran, E.

    2012-10-01

    Due the presence of lot of automotive Industry, Chennai is known as Detroit of India, that producing over 40 % of the Indian vehicle and components. Lean manufacturing concepts have been widely recognized as an important tool in improving the competitiveness of industries. This is a continuous process involving everyone, starting from management to the shop floor. Automotive Component Industries (ACIs) in Ambattur Industrial Estate, Chennai has formed special purpose vehicle (SPV) society namely Ambattur Industrial Estate Manufacturers Association (AIEMA) Technology Centre (ATC) lean manufacturing cluster (ATC-LMC) during July 2010 under lean manufacturing competitiveness scheme, that comes under National Manufacturing Competitiveness Programme of Government of India. The Tripartite Agreement is taken place between National Productivity Council, consultants and cluster (ATC-LMC). The objective is to conduct diagnostic study, study on training and application of various lean manufacturing techniques and auditing in ten ACIs. The methodology adopted is collection of primary data/details from ten ACIs. In the first phase, diagnostic study is done and the areas for improvement in each of the cluster member companies are identified. In the second phase, training programs and implementation is done on 5S and other areas. In the third phase auditing is done and found that the lean manufacturing techniques implementation in ATC-LMC is sustainable and successful in every cluster companies, which will not only enhance competitiveness but also decrease cost, time and increase productivity. The technical efficiency of LMC companies also increases significantly.

  13. Globalisation, Crisis and Industrial Relations in the Indian Auto Industry

    DEFF Research Database (Denmark)

    D'Costa, Anthony

    2011-01-01

    This paper examines how the pattern of investment in the Indian auto industry has changed. The author argues that the industrial relations climate has been an important determinant of that pattern. Industrial relations climate is politically and institutionally determined hence any shift...... in the broader capital-labour relation in the wider global economy due to globalisation is argued to be tempered by India's particular national and local institutions governing industrial relations, unionisation, the specific trajectory of the Indian auto industry, and economic development strategies. When much...... of the global industry is reeling under the financial crisis, India's industry has been expanding. However, the power of workers has been declining in conflict-ridden states just as globalisation and deregulation have hastened capital flight to more pro-business regions. The paper draws some policy implications...

  14. Auto-configuration protocols in mobile ad hoc networks.

    Science.gov (United States)

    Villalba, Luis Javier García; Matesanz, Julián García; Orozco, Ana Lucila Sandoval; Díaz, José Duván Márquez

    2011-01-01

    The TCP/IP protocol allows the different nodes in a network to communicate by associating a different IP address to each node. In wired or wireless networks with infrastructure, we have a server or node acting as such which correctly assigns IP addresses, but in mobile ad hoc networks there is no such centralized entity capable of carrying out this function. Therefore, a protocol is needed to perform the network configuration automatically and in a dynamic way, which will use all nodes in the network (or part thereof) as if they were servers that manage IP addresses. This article reviews the major proposed auto-configuration protocols for mobile ad hoc networks, with particular emphasis on one of the most recent: D2HCP. This work also includes a comparison of auto-configuration protocols for mobile ad hoc networks by specifying the most relevant metrics, such as a guarantee of uniqueness, overhead, latency, dependency on the routing protocol and uniformity.

  15. Error estimation for the linearized auto-localization algorithm.

    Science.gov (United States)

    Guevara, Jorge; Jiménez, Antonio R; Prieto, Jose Carlos; Seco, Fernando

    2012-01-01

    The Linearized Auto-Localization (LAL) algorithm estimates the position of beacon nodes in Local Positioning Systems (LPSs), using only the distance measurements to a mobile node whose position is also unknown. The LAL algorithm calculates the inter-beacon distances, used for the estimation of the beacons' positions, from the linearized trilateration equations. In this paper we propose a method to estimate the propagation of the errors of the inter-beacon distances obtained with the LAL algorithm, based on a first order Taylor approximation of the equations. Since the method depends on such approximation, a confidence parameter τ is defined to measure the reliability of the estimated error. Field evaluations showed that by applying this information to an improved weighted-based auto-localization algorithm (WLAL), the standard deviation of the inter-beacon distances can be improved by more than 30% on average with respect to the original LAL method.

  16. Error Estimation for the Linearized Auto-Localization Algorithm

    Directory of Open Access Journals (Sweden)

    Fernando Seco

    2012-02-01

    Full Text Available The Linearized Auto-Localization (LAL algorithm estimates the position of beacon nodes in Local Positioning Systems (LPSs, using only the distance measurements to a mobile node whose position is also unknown. The LAL algorithm calculates the inter-beacon distances, used for the estimation of the beacons’ positions, from the linearized trilateration equations. In this paper we propose a method to estimate the propagation of the errors of the inter-beacon distances obtained with the LAL algorithm, based on a first order Taylor approximation of the equations. Since the method depends on such approximation, a confidence parameter τ is defined to measure the reliability of the estimated error. Field evaluations showed that by applying this information to an improved weighted-based auto-localization algorithm (WLAL, the standard deviation of the inter-beacon distances can be improved by more than 30% on average with respect to the original LAL method.

  17. AutoCompete: A Framework for Machine Learning Competition

    OpenAIRE

    Thakur, Abhishek; Krohn-Grimberghe, Artus

    2015-01-01

    In this paper, we propose AutoCompete, a highly automated machine learning framework for tackling machine learning competitions. This framework has been learned by us, validated and improved over a period of more than two years by participating in online machine learning competitions. It aims at minimizing human interference required to build a first useful predictive model and to assess the practical difficulty of a given machine learning challenge. The proposed system helps in identifying d...

  18. Testing First-Order Logic Axioms in AutoCert

    Science.gov (United States)

    Ahn, Ki Yung; Denney, Ewen

    2009-01-01

    AutoCert [2] is a formal verification tool for machine generated code in safety critical domains, such as aerospace control code generated from MathWorks Real-Time Workshop. AutoCert uses Automated Theorem Provers (ATPs) [5] based on First-Order Logic (FOL) to formally verify safety and functional correctness properties of the code. These ATPs try to build proofs based on user provided domain-specific axioms, which can be arbitrary First-Order Formulas (FOFs). These axioms are the most crucial part of the trusted base, since proofs can be submitted to a proof checker removing the need to trust the prover and AutoCert itself plays the part of checking the code generator. However, formulating axioms correctly (i.e. precisely as the user had really intended) is non-trivial in practice. The challenge of axiomatization arise from several dimensions. First, the domain knowledge has its own complexity. AutoCert has been used to verify mathematical requirements on navigation software that carries out various geometric coordinate transformations involving matrices and quaternions. Axiomatic theories for such constructs are complex enough that mistakes are not uncommon. Second, adjusting axioms for ATPs can add even more complexity. The axioms frequently need to be modified in order to have them in a form suitable for use with ATPs. Such modifications tend to obscure the axioms further. Thirdly, speculating validity of the axioms from the output of existing ATPs is very hard since theorem provers typically do not give any examples or counterexamples.

  19. A deep auto-encoder model for gene expression prediction.

    Science.gov (United States)

    Xie, Rui; Wen, Jia; Quitadamo, Andrew; Cheng, Jianlin; Shi, Xinghua

    2017-11-17

    Gene expression is a key intermediate level that genotypes lead to a particular trait. Gene expression is affected by various factors including genotypes of genetic variants. With an aim of delineating the genetic impact on gene expression, we build a deep auto-encoder model to assess how good genetic variants will contribute to gene expression changes. This new deep learning model is a regression-based predictive model based on the MultiLayer Perceptron and Stacked Denoising Auto-encoder (MLP-SAE). The model is trained using a stacked denoising auto-encoder for feature selection and a multilayer perceptron framework for backpropagation. We further improve the model by introducing dropout to prevent overfitting and improve performance. To demonstrate the usage of this model, we apply MLP-SAE to a real genomic datasets with genotypes and gene expression profiles measured in yeast. Our results show that the MLP-SAE model with dropout outperforms other models including Lasso, Random Forests and the MLP-SAE model without dropout. Using the MLP-SAE model with dropout, we show that gene expression quantifications predicted by the model solely based on genotypes, align well with true gene expression patterns. We provide a deep auto-encoder model for predicting gene expression from SNP genotypes. This study demonstrates that deep learning is appropriate for tackling another genomic problem, i.e., building predictive models to understand genotypes' contribution to gene expression. With the emerging availability of richer genomic data, we anticipate that deep learning models play a bigger role in modeling and interpreting genomics.

  20. Cyclotron Auto-Resonance Accelerator for environmental applications

    Science.gov (United States)

    Jiang, Yong; Shchelkunov, Sergey V.; Hirshfield, Jay L.

    2017-03-01

    A MW-level CW electron beam source for environmental remediation based on extensions of the scientifically-proven Cyclotron Auto-Resonance Accelerator, dubbed CARA, is described here. CARA is distinguished by its exceptionally high RF-to-beam efficiency, by its production of a self-scanning beam, and by its proportionately lower specific power loading on a beam output window. Its environmental applications include sterilization, flue gas and waste water treatment.

  1. Auto-Coding UML Statecharts for Flight Software

    Science.gov (United States)

    Benowitz, Edward G; Clark, Ken; Watney, Garth J.

    2006-01-01

    Statecharts have been used as a means to communicate behaviors in a precise manner between system engineers and software engineers. Hand-translating a statechart to code, as done on some previous space missions, introduces the possibility of errors in the transformation from chart to code. To improve auto-coding, we have developed a process that generates flight code from UML statecharts. Our process is being used for the flight software on the Space Interferometer Mission (SIM).

  2. Auto-coding UML statecharts for flight software

    OpenAIRE

    Benowitz, Ed; Clark, Ken; Watney, Garth

    2006-01-01

    Statecharts have been used as a means to communicate behaviors in a precise manner between system engineers and software engineers. Handtranslating a statechart to code, as done on some previous space missions, introduces the possibility of errors in the transformation from chart to code. To improve auto-coding, we have developed a process that generates flight code from UML statecharts. Our process is being used for the flight software on the Space Interferometer M...

  3. Reducing auto moiré in discrete line juxtaposed halftoning

    OpenAIRE

    Babaei, Vahid; Hersch, Roger

    2013-01-01

    Discrete line juxtaposed halftoning creates color halftones with discrete colorant lines of freely selectable rational thicknesses laid-out side by side. Screen elements are made of parallelogram screen tiles incorporating the discrete colorant lines. The repetition of discrete colorant lines from one screen element to the next may create auto moiré artifacts. By decomposing each supertile into screen element tiles having slightly different rational thicknesses, we ensure that successive disc...

  4. AutoPyFactory: A Scalable Flexible Pilot Factory Implementation

    Science.gov (United States)

    Caballero, J.; Hover, J.; Love, P.; Stewart, G. A.

    2012-12-01

    The ATLAS experiment at the CERN LHC is one of the largest users of grid computing infrastructure, which is a central part of the experiment's computing operations. Considerable efforts have been made to use grid technology in the most efficient and effective way, including the use of a pilot job based workload management framework. In this model the experiment submits ‘pilot’ jobs to sites without payload. When these jobs begin to run they contact a central service to pick-up a real payload to execute. The first generation of pilot factories were usually specific to a single Virtual Organization (VO), and were bound to the particular architecture of that VO's distributed processing. A second generation provides factories which are more flexible, not tied to any particular VO, and provide new and improved features such as monitoring, logging, profiling, etc. In this paper we describe this key part of the ATLAS pilot architecture, a second generation pilot factory, AutoPyFactory. AutoPyFactory has a modular design and is highly configurable. It is able to send different types of pilots to sites and exploit different submission mechanisms and queue characteristics. It is tightly integrated with the PanDA job submission framework, coupling pilot flow to the amount of work the site has to run. It gathers information from many sources in order to correctly configure itself for a site and its decision logic can easily be updated. Integrated into AutoPyFactory is a flexible system for delivering both generic and specific job wrappers which can perform many useful actions before starting to run end-user scientific applications, e.g., validation of the middleware, node profiling and diagnostics, and monitoring. AutoPyFactory also has a robust monitoring system that has been invaluable in establishing a reliable pilot factory service for ATLAS.

  5. Possibilities of platinum recovery from metal supported spent auto catalysts

    Directory of Open Access Journals (Sweden)

    A. Fornalczyk

    2014-10-01

    Full Text Available The used auto catalytic converter is a valuable source of platinum group metals, so it is important to have it recycled in order to recover precious metals. World literature describes a number of pyro- or hydrometallurgical methods used for recovery of platinum from used automobile catalytic converters. However, all the methods, available in the literature, are used to recover platinum from ceramic carrier. Among automotive catalysts withdrawn from use, these with metallic carrier constitute quite a big group.

  6. [THREE CASES OF ACCIDENTAL AUTO-INJECTION OF ADRENALINE].

    Science.gov (United States)

    Yanagida, Noriyuki; Iikura, Katsuhito; Ogura, Kiyotake; Wang, Ling-jen; Asaumi, Tomoyuki; Sato, Sakura; Ebisawa, Motohiro

    2015-12-01

    Reports on accidental auto-injection of adrenaline are few. We encountered three cases of accidental injection of adrenaline. In this study, we have examined and reported the clinical courses and symptoms of our cases. CASE 1 involved a female physician in her 50s who had attended an explanatory meeting on auto-injection of adrenaline. She mistook EpiPen® to be the EpiPen trainer and accidentally injected herself with 0.3 mg EpiPen®. Her systolic/diastolic pressure peaked at 7 min to reach 144/78 mmHg and decreased to 120/77 mmHg at 14 min. Except for palpitation after 7 min, the only subjective symptom was local pain at the injection site. CASE 2 was noted in a 6-year-old boy. He accidentally pierced his right forefinger with 0.15 mg EpiPen®, and after 20 min, his right forefinger was swollen. The swelling improved 80 min after the accidental injection. CASE 3 was noted in a 4-year-old girl. She accidentally injected herself with 0.15 mg EpiPen®. Her systolic/diastolic pressure peaked at 23 min to reach 123/70 mmHg and decreased to 96/86 mmHg at 28 min. Severe adverse effects of accidental auto-injection of adrenaline were not observed in these three cases. Our findings suggest that while handling adrenaline auto-injectors, we should keep in mind the possibility of accidental injection.

  7. Regulatory T-cell vaccination independent of auto-antigen

    Science.gov (United States)

    Pascual, David W; Yang, Xinghong; Holderness, Kathryn; Jun, SangMu; Maddaloni, Massimo; Kochetkova, Irina

    2014-01-01

    To date, efforts to treat autoimmune diseases have primarily focused on the disease symptoms rather than on the cause of the disease. In large part, this is attributed to not knowing the responsible auto-antigens (auto-Ags) for driving the self-reactivity coupled with the poor success of treating autoimmune diseases using oral tolerance methods. Nonetheless, if tolerogenic approaches or methods that stimulate regulatory T (Treg) cells can be devised, these could subdue autoimmune diseases. To forward such efforts, our approach with colonization factor antigen I (CFA/I) fimbriae is to establish bystander immunity to ultimately drive the development of auto-Ag-specific Treg cells. Using an attenuated Salmonella vaccine expressing CFA/I fimbriae, fimbriae-specific Treg cells were induced without compromising the vaccine's capacity to protect against travelers' diarrhea or salmonellosis. By adapting the vaccine's anti-inflammatory properties, it was found that it could also dampen experimental inflammatory diseases resembling multiple sclerosis (MS) and rheumatoid arthritis. Because of this bystander effect, disease-specific Treg cells are eventually induced to resolve disease. Interestingly, this same vaccine could elicit the required Treg cell subset for each disease. For MS-like disease, conventional CD25+ Treg cells are stimulated, but for arthritis CD39+ Treg cells are induced instead. This review article will examine the potential of treating autoimmune diseases without having previous knowledge of the auto-Ag using an innocuous antigen to stimulate Treg cells via the production of transforming growth factor-β and interleukin-10. PMID:24626168

  8. AutoDJ: the art of electronic music mixing

    Science.gov (United States)

    Lemma, Aweke N.

    2005-10-01

    As a result of advances in audio compression, availability of broadband Internet access at home and the popularity of electronic music distribution systems, today consumers acquire and store ever-increasing number of songs in their local databases. Moreover, consumer-devices with mass random-access storage and sophisticated rendering capabilities make the whole electronic music database available for instant playback. As opposed to traditional music playback where only a limited number of songs are manually selected, there is a strong need for intelligent play-list generation techniques that utilize the whole database while taking the user's interests into account. Moreover, it is desirable to present these songs in a seamlessly streaming manner with smooth transitions. In this paper, we propose a systematic expressive content retrieval system, called AutoDJ, that achieves both objectives. It automatically creates a play-list by sorting songs ac-cording to their low-level features and plays them in a smooth rhythmically consistent way after audio mixing. AutoDJ first builds a profile for each song using features such as tempo, beat and major. Afterwards, it uses a similarity metric to build up a play-list based on a "seed" song. Finally, it introduces smooth transition from one song (profile) to the other by equalizing the tempo and synchronizing the beat phase. We present the system design principles and the signal processing techniques used, as well as a simple AutoDJ demonstrator.

  9. Auto-calibration approach for k-t SENSE.

    Science.gov (United States)

    Ponce, Irene P; Blaimer, Martin; Breuer, Felix A; Griswold, Mark A; Jakob, Peter M; Kellman, Peter

    2014-03-01

    The goal of this work is to increase the spatial resolution of training data, used by reconstruction methods such as k-t SENSE in order to calculate the missing data in a series of dynamic images, without compromising their temporal resolution or acquisition time. The k-t SENSE method allows dynamic imaging at high acceleration factors with high reconstruction quality. However, the low resolution training data required by k-t SENSE may cause undesired temporal filtering effects in the reconstructed images. In this work, a feedback regularization approach is applied to realize auto-calibration of the k-t SENSE algorithm. To that end, a full resolution training data set is calculated from the accelerated data itself using a TSENSE reconstruction. The reconstructed training data are then fed back for the actual k-t SENSE reconstruction. For evaluation of our approach, temporal filtering effects are quantified by calculating the modulation transfer function and noise measurements are done by Monte-Carlo simulations. Computer simulations and cardiac imaging experiments demonstrate an improved temporal fidelity of auto-calibrated k-t SENSE compared to standard k-t SENSE. Auto-calibrated k-t SENSE provides high quality reconstructions for dynamic imaging applications. Copyright © 2013 Wiley Periodicals, Inc.

  10. Graph Regularized Auto-Encoders for Image Representation.

    Science.gov (United States)

    Yiyi Liao; Yue Wang; Yong Liu

    2017-06-01

    Image representation has been intensively explored in the domain of computer vision for its significant influence on the relative tasks such as image clustering and classification. It is valuable to learn a low-dimensional representation of an image which preserves its inherent information from the original image space. At the perspective of manifold learning, this is implemented with the local invariant idea to capture the intrinsic low-dimensional manifold embedded in the high-dimensional input space. Inspired by the recent successes of deep architectures, we propose a local invariant deep nonlinear mapping algorithm, called graph regularized auto-encoder (GAE). With the graph regularization, the proposed method preserves the local connectivity from the original image space to the representation space, while the stacked auto-encoders provide explicit encoding model for fast inference and powerful expressive capacity for complex modeling. Theoretical analysis shows that the graph regularizer penalizes the weighted Frobenius norm of the Jacobian matrix of the encoder mapping, where the weight matrix captures the local property in the input space. Furthermore, the underlying effects on the hidden representation space are revealed, providing insightful explanation to the advantage of the proposed method. Finally, the experimental results on both clustering and classification tasks demonstrate the effectiveness of our GAE as well as the correctness of the proposed theoretical analysis, and it also suggests that GAE is a superior solution to the current deep representation learning techniques comparing with variant auto-encoders and existing local invariant methods.

  11. Death and Taxes: Auto Dealers Face Their Final Reckoning

    Directory of Open Access Journals (Sweden)

    Robert Hutchinson

    2013-07-01

    While a paring down of the auto retail industry, particularly the domestic dealer networks, may be necessary and even welcomed by surviving dealers and the manufacturers they represent, the impact of this sector of the economy cannot be understated. Despite its importance, it has been often overlooked, as the government and public have focused their attention on large individual corporations, such as banks and the auto manufacturers themselves. While even the largest private dealerships in the nation, and even the large publicly-traded dealers such as Auto Nation and J.D. Buyrider, are relatively small in comparison with the likes of General Motors, Chrysler, AIG, Bank of America, etc., collectively they make up the single largest portion of the retail sector of the economy at 17%, accounting for $789B in annual sales in 2008[i] and 1,114,500 jobs with an annual payroll of $54B in 2007[ii]. Moreover, many dealers represent the backbone of small business, especially in small and rural communities throughout the country, paying some $20B in annual sales taxes to state and local municipalities.[iii

  12. Lipid Accumulation Mechanisms in Auto- and Heterotrophic Microalgae.

    Science.gov (United States)

    Chen, Hao-Hong; Jiang, Jian-Guo

    2017-09-20

    Microalgae lipids have attracted great attention in the world as a result of their potential use for biodiesel productions. Microalgae are cultivated in photoautotrophic conditions in most cases, but several species are able to grow under heterotrophic conditions, in which microalgae are cultivated in the dark where the cell growth and reproduction are supported by organic carbons. This perspective is covering the related studies concerning the difference between hetero- and autotrophic cultivation of microalgae. The auto- and heterotrophic central carbon metabolic pathways in microalgae are described, and the catalyzing reactions of several key metabolic enzymes and their corresponding changes in the protein level are summarized. Under adverse environmental conditions, such as nutrient deprivation, microalgae have the ability to highly store energy by forming triacylglycerol (TAG), the reason for which is analyzed. In addition, the biosynthesis of fatty acids and TAGs and their difference between auto- and heterotrophic conditions are compared at the molecular level. The positive regulatory enzymes, such as glucose transporter protein, fructose-1,6-bisphosphate aldolase, and glycerol-3-phosphate dehydrogenase, and the negative regulation enzymes, such as triose phosphate isomerase, played a crucial role in the lipid accumulation auto- and heterotrophic conditions.

  13. AutoCAD electrical 2016 for electrical control designers

    CERN Document Server

    Tickoo, Sham

    2016-01-01

    The AutoCAD Electrical 2016 for Electrical Control Designers textbook has been written to assist the engineering students and the practicing designers who are new to AutoCAD Electrical. Using this textbook, the readers can learn the application of basic tools required for creating professional electrical control drawings with the help of AutoCAD Electrical. Keeping in view the varied requirements of the users, this textbook covers a wide range of tools and features such as schematic drawings, Circuit Builder, panel drawings, parametric and nonparametric PLC modules, stand-alone PLC I/O points, ladder diagrams, point-to-point wiring diagrams, report generation, creation of symbols, and so on. This will help the readers to create electrical drawings easily and effectively. Special emphasis has been laid on the introduction of concepts, which have been explained using text and supported with graphical examples. The examples and tutorials used in this book ensure that the users can relate the information provided...

  14. Interpolis SlimOpWeg-programma : de AutoModus-app : vragenlijstonderzoek naar het effect van een app om smartphonegebruik in de auto te verminderen.

    NARCIS (Netherlands)

    Groot-Mesken, J. de Wijnen, W. Stelling-Konczak, A. & Commandeur, J.J.F.

    2017-01-01

    Interpolis SlimOpWeg programme: the AutoModus app; Survey into the effect of an app on reducing smartphone use while driving a car. Within the programme SlimOpWeg the Dutch insurance company Interpolis had a smartphone app developed. The purpose of this ‘AutoModus app’ is to help young drivers to

  15. Cyber-intrusion Auto-response and Policy Management System (CAPMS)

    Energy Technology Data Exchange (ETDEWEB)

    Lusk, Steve [ViaSat Inc., Boston, MA (United States); Lawrence, David [Duke Energy, Charlotte, NC (United States); Suvana, Prakash [Southern California Edison, Rosemead, CA (United States)

    2015-11-11

    The Cyber-intrusion Auto-response and Policy Management System (CAPMS) project was funded by a grant from the US Department of Energy (DOE) Cybersecurity for Energy Delivery Systems (CEDS) program with contributions from two partner electric utilities: Southern California Edison (SCE) and Duke Energy. The goal of the project was to demonstrate protecting smart grid assets from a cyber attack in a way that “does not impede critical energy delivery functions.” This report summarizes project goals and activities for the CAPMS project and explores what did and did not work as expected. It concludes with an assessment of possible benefits and value of the system for the future.

  16. AutoTutor: a human tutoring simulation with an animated pedagogical interface

    Science.gov (United States)

    Craig, Scotty D.; Hu, Xiangen; Gholson, Barry; Marks, William; Graesser, Arthur C.

    2000-11-01

    This paper presents an overview AutoTutor, an intelligent tutoring system that engages in conversationally smooth dialogue with students. AutoTutor simulates the discourse patterns and dialogue moves of human tutors with modest tutoring expertise. In order to concretize the situation we begin with two short snapshots of AutoTutor in action. In one snapshot, involving an articulate and knowledgeable student, AutoTutor begins with a how question and then simply pumps for further information. In the other, with an inarticulate and less knowledgeable student AutoTutor begins with a why question and follows this with numerous hints and prompts until the topic is covered. The remainder of the paper describes the system's architecture, which is comprised of seven modules: a curriculum script, language extraction, speech act classification, latent semantic analysis, topic selection, dialogue move generation, and animated agent. AutoTutor responds to the learner in real time and runs of a single Pentium processor.

  17. Productivity enhancement and reliability through AutoAnalysis

    Science.gov (United States)

    Garetto, Anthony; Rademacher, Thomas; Schulz, Kristian

    2015-09-01

    The decreasing size and increasing complexity of photomask features, driven by the push to ever smaller technology nodes, places more and more challenges on the mask house, particularly in terms of yield management and cost reduction. Particularly challenging for mask shops is the inspection, repair and review cycle which requires more time and skill from operators due to the higher number of masks required per technology node and larger nuisance defect counts. While the measurement throughput of the AIMS™ platform has been improved in order to keep pace with these trends, the analysis of aerial images has seen little advancement and remains largely a manual process. This manual analysis of aerial images is time consuming, dependent on the skill level of the operator and significantly contributes to the overall mask manufacturing process flow. AutoAnalysis, the first application available for the FAVOR® platform, offers a solution to these problems by providing fully automated analysis of AIMS™ aerial images. Direct communication with the AIMS™ system allows automated data transfer and analysis parallel to the measurements. User defined report templates allow the relevant data to be output in a manner that can be tailored to various internal needs and support the requests of your customers. Productivity is significantly improved due to the fast analysis, operator time is saved and made available for other tasks and reliability is no longer a concern as the most defective region is always and consistently captured. In this paper the concept and approach of AutoAnalysis will be presented as well as an update to the status of the project. The benefits arising from the use of AutoAnalysis will be discussed in more detail and a study will be performed in order to demonstrate.

  18. Transparency and the logic of auto-immunity

    Directory of Open Access Journals (Sweden)

    Emanuele Antonelli

    2011-12-01

    Full Text Available In Voyous, Jacques Derrida develops his argument starting from the presupposition that democracy as such is the entity whose integrity and immunity are at stake and, therefore, under investigation. This gesture reflects the setting in which ten years before, in Foi et savoir, he had cast his reasoning about the logic of immunity. There, it was one of the sources of religion, the immunity of the sacred, that operated according to this logic. The hyphen between these two essays, beside Derrida’s own crossed references, is the genealogical reasoning on the meaning and essence of the concept of democracy: contrary to what Derrida claims, it will be maintained that Athenian democracy had a clear immune matrix, whose constant exercise is clearly defined, in spite of himself, by Vernant, and it will be shown how modern democracy has been forced to change policy. Modern democracy is an entity characterized by an immune deficiency. In order to save Derrida’s intuition from both the collapse of different vantage points and from a quite bizarre reticence in taking into account of the immune value of rituals, our starting point will be René Girard’s œuvre and his reading of the role of immune logic in sacred systems and, more generally, in modernity. The threshold between the auto-immune reaction, immune deficiency and auto-immune disease, between the sacrifice who delimits and constitutes the self and the holocauste du peuple en détail, is the space where, constantly exposed to the risk of auto-denial, democracy lives. 

  19. Auto-interpreter for CYP2D6 SNaPshot genotyping.

    Science.gov (United States)

    Ong, Sungmoon; Jeong, Hye-Eun; Lee, Sang Seop; Shon, Ji-Hong; Shin, Jae-Gook; Kim, Eun-Young

    2008-11-06

    CYP2D6 genotyping using SNaPshot method is a very useful tool clinically. However it's hard to interpret the obtained data as a genotype without training. Thus SNaPshot auto-interpreter for the genotype was designed to interpret obtained raw data to a genotype. The auto-interpreter showed good concordance with experts' reading. The validated auto-interpreter of CYP2D6 genotyping using SNaPshot can contribute to accelerating the clinical use.

  20. Magnonic Crystal as a Delay Line for Low-Noise Auto-Oscillator

    Science.gov (United States)

    2015-05-12

    Magnonic crystal as a delay line for low-noise auto -oscillator Elena Bankowski and Thomas Meitzler U.S. Army TARDEC, Warren, Michigan 48397, USA...authors propose to use the magnonic crystal patterned on the YIG magnetic film as an efficient delay line in the feedback loop of tunable auto -oscillator...noise properties of the auto -oscillator. I. INTRODUCTION Spin waves propagating in thin YIG films have use- ful properties that are suitable for the

  1. Benchmark para la Evaluación de Algoritmos de Auto-ajuste de Controladores PID

    Directory of Open Access Journals (Sweden)

    Julio A. Romero

    2011-01-01

    Full Text Available Resumen: En este documento se propone un benchmark para la evaluación de algoritmos de auto-ajuste de controladores PID. Para ello se definen índices cuantitativos que permiten medir el comportamiento de los algoritmos, tanto durante la realización del experimento como en la fase de control. El benchmark presentado pretende ser una herramienta que permita realizar estudios comparativos entre algoritmos de auto-ajuste. Palabras clave: Benchmark, Auto-ajuste, PID

  2. Inhibition of Hydroxyquinol Auto-Oxidation by a Cell Extract of Trichosporon cutaneum

    OpenAIRE

    Katsunori, Suzuki; Masao, ITOH; Department of Agricultural Chemistry, Faculty of Agriculture, Tokyo University

    1986-01-01

    A cell extract from acetate-grown Trichosporon cutaneum WY2-2 inhibited auto-oxidation of phenolics, especially that of hydroxyquinol. It prevented auto-oxidation of hydroxyquinol without direct interaction with hydroxyquinol. Bovine erythrocyte superoxide dismutase had similar characteristics as the cell extract, and the elution patterns of superoxide dismutase activity and of the inhibitory activity to hydroxyquinol auto-oxidation from a Sephadex G-150 column coincided. These results indica...

  3. Engineering drawing from first principles using AutoCAD

    CERN Document Server

    Maguire, Dennis E

    1998-01-01

    Engineering Drawing From First Principles is a guide to good draughting for students of engineering who need to learn how to produce technically accurate and detailed designs to British and International Standards. Written by Dennis Maguire, an experienced author and City and Guilds chief examiner, this text is designed for use on Further Education and University courses where a basic understanding of draughtsmanship and CAD is necessary. Although not written as an AutoCAD tutor, the book will be a useful introduction to good CAD practice.Part of the Revision and Self-Assessmen

  4. Bonding auto-polymerising acrylic resin to acrylic denture teeth.

    LENUS (Irish Health Repository)

    Nagle, Susan

    2009-09-01

    This study investigated the effect of surface treatments on the shear bond strength of an auto-polymerising acrylic resin cured to acrylic denture teeth. The surface treatments included a combination of grit-blasting and\\/or wetting the surface with monomer. Samples were prepared and then stored in water prior to shear testing. The results indicated that the application of monomer to the surface prior to bonding did not influence the bond strength. Grit blasting was found to significantly increase the bond strength.

  5. Essai pratique de performance des masques auto-sauveteurs SAVOX

    CERN Multimedia

    CERN DGS/GS/PT; N. Dupont-Sagorin

    2009-01-01

    Cette vidéo présente l'essai pratique de performance (EPP) des masques auto-sauveteurs Savox (MSA) par 10 volontaires. Répartis en groupes effectuant différents niveaux d'activité physique, ils ont porté le masque pendant 23 à 51 minutes et ont parcouru de 2,4 à 3,6 km. Des paramètres physiques et subjectifs ont été relevés durant l'essai.

  6. Mazda kiintotyövaiheiden perustaminen : Delta Auto Oy

    OpenAIRE

    Schreck, Ville

    2012-01-01

    Täyden palvelun autoliikeketju Delta Auto myy ja huoltaa Kia-, Mitsubishi- ja Mazda-merkkisiä autoja paikkakuntakohtaisesti kahdessakymmenessäviidessä toimipisteessä. Opinnäytetyön tarkoituksena oli tehdä toimiva ratkaisu Mazdan työvaiheiden sekä työpakettien myyntiin Automaster-ohjelmistoon. Työvaiheet sekä ohjeajat tulevat käyttöön kaikkiin Delta Auton toimipisteisiin ympäri Suomea. Työn lähdemateriaalin sain Inchcape Motor Finland Oy:ltä, joka toimii Suomessa Mazdan maahantuojana. Tarve tä...

  7. RFID and Auto-ID in planning and logistics

    CERN Document Server

    Jones, Erick C

    2011-01-01

    As RFID technology is becoming increasingly popular, the need has arisen to address the challenges and approaches to successful implementation. RFID and Auto-ID in Planning and Logistics: A Practical Guide for Military UID Applications presents the concepts for students, military personnel and contractors, and corporate managers to learn about RFID and other automatic information capture technologies, and their integration into planning and logistics functions. The text includes comparisons of RFID with technologies such as bar codes, satellite tags, and global positioning systems and provides

  8. AutoCAD Civil 3D 2014 essentials

    CERN Document Server

    Chappell, Eric

    2013-01-01

    Quickly learn essential Civil 3D tools and techniques Get a thorough introduction to AutoCAD Civil 3D, the industry-leading engineering software used to design roads, highways, subdivisions, drainage and sewer systems, and more. This Autodesk Official Press book is a unique learning resource that features concise, straightforward explanations and real-world, hands-on exercises and tutorials. With compelling full-color screenshots and approachable exercises that demonstrate core features and functions, the book helps you gain understanding and confidence as you master this premiere

  9. Visual Auto-landing of an Autonomous Aircraft

    OpenAIRE

    Rives, Patrick; Azinheira, José Raul

    2002-01-01

    This report is the summary of work done in the CIMAR project of collaboration between IST (Lisboa) and the Icare Project (INRIA Sophia Antipolis) for vision-based control applied to an autonomous aircraft. An unified modeling framework is defined and the vision-based auto-landing of the UAV model is analyzed, based on the classical alternative between position-based and image-based visual control. The controller design is adapted for both approaches and simulations results are presented in or...

  10. Up and running with AutoCAD 2014 2D and 3D drawing and modeling

    CERN Document Server

    Gindis, Elliot

    2013-01-01

    Get ""Up and Running"" with AutoCAD using Gindis's combination of step-by-step instruction, examples, and insightful explanations. The emphasis from the beginning is on core concepts and practical application of AutoCAD in architecture, engineering and design. Equally useful in instructor-led classroom training, self-study, or as a professional reference, the book is written with the user in mind by a long-time AutoCAD professional and instructor based on what works in the industry and the classroom. Strips away complexities, both real and perceived, and reduces AutoCAD t

  11. Auto-calibration system of EMG sensor suit

    Science.gov (United States)

    Suzuki, Yousuke; Tanaka, Takayuki; Feng, Maria Q.

    2005-12-01

    Biogenic measurement has been studied as a robot's interface. We have studied the wearable sensor suit as a robot's interface. Some kinds of sensor disks are embedded the sensor suit to the wet suit-like material. The sensor suit measures a wearing person's joint, and muscular activity. In this report, we aim to establish an auto-calibration system for measuring joint torques by using EMG sensors based on neural network and sensor disks of a lattice. The Torque presumption was performed using the share neural network, which learned the data that formed the whole subject's teacher data. Additional training of the share neural network was carried out using the individual teaching data. As a result, that was able to do the neural network training in short time, high probability and high accuracy to training of initial neural network. Moreover, high-presumed accuracy was able to be acquired by this method Next, Sensor disks of a lattice was developed. EMG is measurable, checking the state of an electrode by that can measure biogenic impedance. That was able to measure EMG by sensor disks which has low impedance We measured EMG and joint torque by trial production sensor suit and torque measuring instrument. The predominancy of the torque presumption using the share neural network was check. We proposed Measurement system, which consists sensor disk of lattice. Experimental results show the proposed method is effective for the auto-calibration.

  12. AutoPyFactory: A Scalable Flexible Pilot Factory Implementation

    CERN Document Server

    Caballero, J; The ATLAS collaboration; Love, P; Stewart, G

    2012-01-01

    The ATLAS experiment at the CERN LHC is one of the largest users of grid computing infrastructure, which is a central part of the experiment’s computing operations. Considerable efforts have been made to use grid technology in the most efficient and effective way, including the use of a pilot job based workload management framework. In this model the experiment submits ’pilot’ jobs to sites without payload. When these jobs begin to run they contact a central service to retrieve a real payload to execute. The first generation of pilot factories were usually specific to a single VO, and were bound to the particular architecture of that VO’s distributed processing. A second generation provides factories which are more flexible, not tied to any particular VO, and provide new or improved features such as monitoring, logging, profiling, etc. In this paper we describe this key part of the ATLAS pilot architecture, a second generation pilot factory, AutoPyFactory. AutoPyFactory has a modular design and is hig...

  13. BCG and protection against inflammatory and auto-immune diseases.

    Science.gov (United States)

    Kowalewicz-Kulbat, Magdalena; Locht, Camille

    2017-07-01

    Bacillus Calmette-Guérin (BCG) is the only available vaccine against tuberculosis. Although its protective efficacy against pulmonary tuberculosis is still under debate, it provides protection against other mycobacterial diseases. BCG is also an effective therapy against superficial bladder cancer and potentially decreases overall childhood mortality. Areas covered: The purpose of this paper is to provide a state-of-the-art summary of the beneficial effects of BCG in inflammatory and auto-immune diseases. As a strong inducer of Th1 type immunity, BCG has been reported to protect against atopic conditions, such as allergic asthma, a Th2-driven disorder. Its protective effect has been well documented in mice, but still awaits definitive evidence in humans. Similarly, murine studies have shown a protective effect of BCG against auto-immune diseases, such as multiple sclerosis and insulin-dependent diabetes, but studies in humans have come to conflicting conclusions. Expert commentary: Studies in mice have shown a beneficial effect of the BCG vaccine against allergic asthma, multiple sclerosis and diabetes. However, the understanding of its mechanism is still fragmentary and requires further in depth research. Some observational or intervention studies in humans have also suggested a beneficial effect, but definitive evidence for this requires confirmation in carefully conducted prospective studies.

  14. An improved auto-tuning scheme for PID controllers.

    Science.gov (United States)

    Dey, Chanchal; Mudi, Rajani K

    2009-10-01

    An improved auto-tuning scheme is proposed for Ziegler-Nichols (ZN) tuned PID controllers (ZNPIDs), which usually provide excessively large overshoots, not tolerable in most of the situations, for high-order and nonlinear processes. To overcome this limitation ZNPIDs are upgraded by some easily interpretable heuristic rules through an online gain modifying factor defined on the instantaneous process states. This study is an extension of our earlier work [Mudi RK., Dey C. Lee TT. An improved auto-tuning scheme for PI controllers. ISA Trans 2008; 47: 45-52] to ZNPIDs, thereby making the scheme suitable for a wide range of processes and more generalized too. The proposed augmented ZNPID (AZNPID) is tested on various high-order linear and nonlinear dead-time processes with improved performance over ZNPID, refined ZNPID (RZNPID), and other schemes reported in the literature. Stability issues are addressed for linear processes. Robust performance of AZNPID is observed while changing its tunable parameters as well as the process dead-time. The proposed scheme is also implemented on a real time servo-based position control system.

  15. Auto-Configuration Protocols in Mobile Ad Hoc Networks

    Directory of Open Access Journals (Sweden)

    Julián García Matesanz

    2011-03-01

    Full Text Available The TCP/IP protocol allows the different nodes in a network to communicate by associating a different IP address to each node. In wired or wireless networks with infrastructure, we have a server or node acting as such which correctly assigns IP addresses, but in mobile ad hoc networks there is no such centralized entity capable of carrying out this function. Therefore, a protocol is needed to perform the network configuration automatically and in a dynamic way, which will use all nodes in the network (or part thereof as if they were servers that manage IP addresses. This article reviews the major proposed auto-configuration protocols for mobile ad hoc networks, with particular emphasis on one of the most recent: D2HCP. This work also includes a comparison of auto-configuration protocols for mobile ad hoc networks by specifying the most relevant metrics, such as a guarantee of uniqueness, overhead, latency, dependency on the routing protocol and uniformity.

  16. Auto insurance fraud detection using unsupervised spectral ranking for anomaly

    Directory of Open Access Journals (Sweden)

    Ke Nian

    2016-03-01

    Full Text Available For many data mining problems, obtaining labels is costly and time consuming, if not practically infeasible. In addition, unlabeled data often includes categorical or ordinal features which, compared with numerical features, can present additional challenges. We propose a new unsupervised spectral ranking method for anomaly (SRA. We illustrate that the spectral optimization in SRA can be viewed as a relaxation of an unsupervised SVM problem. We demonstrate that the first non-principal eigenvector of a Laplacian matrix is linked to a bi-class classification strength measure which can be used to rank anomalies. Using the first non-principal eigenvector of the Laplacian matrix directly, the proposed SRA generates an anomaly ranking either with respect to the majority class or with respect to two main patterns. The choice of the ranking reference can be made based on whether the cardinality of the smaller class (positive or negative is sufficiently large. Using an auto insurance claim data set but ignoring labels when generating ranking, we show that our proposed SRA significantly surpasses existing outlier-based fraud detection methods. Finally we demonstrate that, while proposed SRA yields good performance for a few similarity measures for the auto insurance claim data, notably ones based on the Hamming distance, choosing appropriate similarity measures for a fraud detection problem remains crucial.

  17. SURFACE INTEGRITY EVALUATION OF TURNING WITH AUTO-ROTATING TOOL

    Directory of Open Access Journals (Sweden)

    Jozef Struharnansky

    2016-09-01

    Full Text Available The technical practice requirements comes to have increased demands on higher productivity, speed and quality of the machining process of various materials. Hard to machine materials, whose machining led to the development of turning with rotating cutting edge are not an exception. The machining process of auto-rotating tool is more complicated than the conventional process of turning, especially for the process of reshaping cutting layers into chips. There is a significant load in the system, that may affect the life of the cutting edge of the tool as well as the whole system and also in the final extent of the qualitative parameters of the workpiece (product / product. The article specifies the knowledge and findings of measurement in machining material 100Cr6 with an auto-rotating tool. The measurements were conducted to evaluate the integrity of the surface (roughness of the workpiece to the impacts of cutting conditions, in particular the feed and the cutting edge inclination. It also analyzes the presence (size, character, action of residual stresses concentrated in the surface layers of the workpiece by changing the cutting conditions.

  18. Auto-Configuration Protocols in Mobile Ad Hoc Networks

    Science.gov (United States)

    Villalba, Luis Javier García; Matesanz, Julián García; Orozco, Ana Lucila Sandoval; Díaz, José Duván Márquez

    2011-01-01

    The TCP/IP protocol allows the different nodes in a network to communicate by associating a different IP address to each node. In wired or wireless networks with infrastructure, we have a server or node acting as such which correctly assigns IP addresses, but in mobile ad hoc networks there is no such centralized entity capable of carrying out this function. Therefore, a protocol is needed to perform the network configuration automatically and in a dynamic way, which will use all nodes in the network (or part thereof) as if they were servers that manage IP addresses. This article reviews the major proposed auto-configuration protocols for mobile ad hoc networks, with particular emphasis on one of the most recent: D2HCP. This work also includes a comparison of auto-configuration protocols for mobile ad hoc networks by specifying the most relevant metrics, such as a guarantee of uniqueness, overhead, latency, dependency on the routing protocol and uniformity. PMID:22163814

  19. The Expanded Use of Auto-augmentation Techniques in Oncoplastic Breast Surgery.

    Science.gov (United States)

    Losken, Albert; Hart, Alexandra M; Dutton, James Walter; Broecker, Justine S; Styblo, Toncred M; Carlson, Grant W

    2017-09-13

    Auto-augmentation techniques have been applied to oncoplastic reductions to assist with filling larger, more remote defects and women with smaller breasts. The purpose of this report is to describe the use of auto-augmentation techniques in OR and compare the results with traditional OR. We queried a prospectively maintained database of all women who underwent partial mastectomy and OR between 1994 and October 2015. The auto-augmentation techniques were defined as 1) extended primary nipple auto-augmentation pedicle, and 2) primary nipple pedicle and secondary auto-augmentation pedicle. Comparisons were made to a control oncoplastic group. There were a total of 333 patients, 222 patients (67.7%) without auto-augmentation and 111 patients (33%) with auto-augmentation. Fifty-one patients had extended auto-augmentation pedicle, and 60 patients with a secondary auto-augmentation pedicle. Biopsy weight was smallest in the extended pedicle group (136 grams) and largest in the regular oncoplastic group (235 grams, p=0.017). Superomedial was the most common extended pedicle and lateral being the most common location. Inferorolateral was the most common secondary pedicle for lateral and upper outer defects. There were no significant differences in the overall complication rate: 15.5% in the regular oncoplastic group, 19.6% in the extended pedicle group, and 20% in the secondary pedicle group. Auto-augmentation techniques have evolved to manage complex defects not amenable to standard oncoplastic reduction methods. They are often required for lateral defects especially in smaller breasts. Auto-augmentation can be done safely without increase risk of complications, broadening the indications for breast conservation therapy.

  20. Unintentional Epinephrine Auto-injector Injuries: A National Poison Center Observational Study.

    Science.gov (United States)

    Anshien, Marco; Rose, S Rutherfoord; Wills, Brandon K

    2016-11-24

    Epinephrine is the only first-line therapeutic agent used to treat life-threatening anaphylaxis. Epinephrine auto-injectors are commonly carried by patients at risk for anaphylaxis, and reported cases of unintentional auto-injector injury have increased over the last decade. Modifications of existing designs and release of a new style of auto-injector are intended to reduce epinephrine auto-injector misuse. The aim of the study was to characterize reported cases of unintentional epinephrine auto-injector exposures from 2013 to 2014 and compare demographics, auto-injector model, and anatomical site of such exposures. The American Association of Poison Control Center's National Poison Data System was searched from January 1, 2013, to December 31, 2014, for cases of unintentional epinephrine auto-injector exposures. Anatomical site data were obtained from all cases reported to the Virginia Poison Center and participating regional poison center for Auvi-Q cases. A total of 6806 cases of unintentional epinephrine auto-injector exposures were reported to US Poison Centers in 2013 and 2014. Of these cases, 3933 occurred with EpiPen, 2829 with EpiPen Jr, 44 with Auvi-Q, and no case reported of Adrenaclick. The most common site of unintentional injection for traditional epinephrine auto-injectors was the digit or thumb, with 58% of cases for EpiPen and 39% of cases with EpiPen Jr. With Auvi-Q, the most common site was the leg (78% of cases). The number of unintentional epinephrine auto-injector cases reported to American Poison Centers in 2013-2014 has increased compared with previous data. Most EpiPen exposures were in the digits, whereas Auvi-Q was most frequently in the leg. Because of the limitations of Poison Center data, more research is needed to identify incidence of unintentional exposures and the effectiveness of epinephrine auto-injector redesign.

  1. Avaliação do resultado de um programa educativo dirigido a paraplégicos visando o autocuidado relacionado aos déficits identificados na eliminação intestinal Evaluación del resultado de un programa educativo dirigido a parapléjicos visando el auto cuidado relacionado a los déficits identificados en la eliminación intestinal Effect of an educational program in intestinal elimination self-care deficits among individuals with paraplegia

    Directory of Open Access Journals (Sweden)

    Marcele Pescuma Capeletti Padula

    2007-06-01

    Full Text Available OBJETIVOS: Avaliar o progresso de paraplégicos na assunção do autocuidado, após a implementação de um programa educativo relacionado a 16 déficits identificados na eliminação intestinal; verificar a influência do nível neurológico da lesão e lócus de controle à saúde na assunção do autocuidado. MÉTODOS: Estudo semi-experimental com 28 pacientes, 14 pertencentes ao grupo experimental aos quais aplicou-se o programa educativo e 14 do grupo controle submetidos ao tratamento convencional da instituição. Foram atribuídos escores às ações de enfermagem: fazer - 4, guiar - 3, apoiar - 2, ensinar - 1, independente - 0. RESULTADOS: O grupo experimental progrediu significativamente na assunção do autocuidado em comparação com o grupo controle (teste de Quiquadrado p-valueOBJETIVOS: Evaluar el progreso de los pacientes parapléjicos en la asunción del auto cuidado después de la implantación de un programa educativo relacionado a 16 déficits identificados en la eliminación intestinal; verificar la influencia del nivel neurológico de lesión y locus de control a la salud en la asunción del auto cuidado. MÉTODOS: Estudio cuasi experimental realizado con 28 pacientes, 14 pertenecientes al grupo experimental a quienes se les aplicó el programa educativo y 14 del grupo control sometidos al tratamiento convencional de la institución. Fueron atribuidos puntuaciones a las acciones de enfermería: hacer -4, guiar - 3, apoyar - 2, enseñar - 1, independiente - 0. RESULTADOS: El grupo experimental progresó significativamente en la asunción del auto cuidado en comparación al grupo control (test de Chi cuadrado p-valueOBJECTIVES: To evaluate self-care progress of individuals with paraplegia who attended an educational program regarding 16 intestinal elimination self-care deficits, and to determine the influence of the neurological level of the injury and locus of control on the progress of the self-care. METHODS: A quasi

  2. Auto-calibration of capacitive MEMS accelerometers based on pull-in voltage

    NARCIS (Netherlands)

    Rocha, L.A.; Dias, R.A.; Cretu, E.; Mol, L.; Wolffenbuttel, R.F.

    2011-01-01

    This paper describes an electro-mechanical auto-calibration technique for use in capacitive MEMS accelerometers. Auto-calibration is achieved using the combined information derived from an initial measurement of the resonance frequency and the measurement of the pull-in voltages during device

  3. Auto-correlation analysis of wave heights in the Bay of Bengal

    Indian Academy of Sciences (India)

    Time series observations of significant wave heights in the Bay of Bengal were subjected to auto- correlation analysis to determine temporal variability scale. The analysis indicates an exponen- tial fall of auto-correlation in the first few hours with a decorrelation time scale of about six hours. A similar figure was found earlier ...

  4. Automation of AutoCAD for Detailing of Reinforced Concrete Dog ...

    African Journals Online (AJOL)

    AutoLISP was used to automate AutoCAD to produce reinforced concrete drawing of a half-turn dog-leg staircase, on receiving information relating to geometry and related parameters. This was done to improve efficiency as well as to save time and effort during structural detailing of the staircase type. The software ...

  5. 46 CFR 28.875 - Radar, depth sounding, and auto-pilot.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Radar, depth sounding, and auto-pilot. 28.875 Section 28.875 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY UNINSPECTED VESSELS REQUIREMENTS FOR COMMERCIAL FISHING INDUSTRY VESSELS Aleutian Trade Act Vessels § 28.875 Radar, depth sounding, and auto-pilot...

  6. [Auto-immune disorders as a possible cause of neuropsychiatric syndromes].

    Science.gov (United States)

    Martinez-Martinez, P; Molenaar, P C; Losen, M; Hoffmann, C; Stevens, J; de Witte, L D; van Amelsvoort, T; van Os, J; Rutten, B P F

    2015-01-01

    Changes that occur in the behaviour of voltage-gated ion channels and ligand-gated receptor channels due to gene mutations or auto-immune attack are the cause of channelopathies in the central and peripheral nervous system. Although the relation between molecular channel defects and clinical symptoms has been explained in the case of many neuromuscular channelopathies, the pathophysiology of auto-immunity in neuropsychiatric syndromes is still unclear. To review recent findings regarding neuronal auto-immune reactions in severe neuropsychiatric syndromes. Using PubMed, we consulted the literature published between 1990 and August 2014 relating to the occurrence of auto-immune antibodies in severe and persistent neuropsychiatric syndromes. Auto-antibodies have only limited access to the central nervous system, but if they do enter the system they can, in some cases, cause disease. We discuss recent findings regarding the occurrence of auto-antibodies against ligand-activated receptor channels and potassium channels in neuropsychiatric and neurological syndromes, including schizophrenia and limbic encephalitis. Although the occurrence of several auto-antibodies in schizophrenia has been confirmed, there is still no proof of a causal relationship in the syndrome. We still have no evidence of the prevalence of auto-immunity in neuropsychiatric syndromes. The discovery that an antibody against an ion channel is associated with some neuropsychiatric disorders may mean that in future it will be possible to treat patients by means of immunosuppression, which could lead to an improvement in a patient's cognitive abilities.

  7. 28 CFR 25.56 - Responsibilities of junk yards and salvage yards and auto recyclers.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Responsibilities of junk yards and salvage yards and auto recyclers. 25.56 Section 25.56 Judicial Administration DEPARTMENT OF JUSTICE... Responsibilities of junk yards and salvage yards and auto recyclers. (a) By no later than March 31, 2009, and...

  8. Auto-Graph: Considering the Utility of Student Behaviour Self-Monitoring for Inclusive Schools

    Science.gov (United States)

    Jull, Stephen K.

    2006-01-01

    This paper reports the outcomes of a small-scale exploratory study that examined the utility of a novel computer-supported student behaviour self-monitoring procedure called Auto-Graph. The Auto-Graph procedure is a universal classroom behaviour management strategy for responding to disruptive antisocial behaviours. It was designed to provide…

  9. Interpolis SlimOpWeg-programma : de AutoModus-app : samenvatting onderzoeksresultaten.

    NARCIS (Netherlands)

    2016-01-01

    Interpolis heeft in het kader van het SlimOpWeg-programma een app voor de smartphone laten ontwikkelen. Het doel van deze ‘AutoModus-app’ is om jongeren te helpen hun smart phonegebruik in de auto te verminderen. Afleiding door mobiel telefoongebruik vormt namelijk een groot verkeers

  10. AUTO-MUTE 2.0: A Portable Framework with Enhanced Capabilities for Predicting Protein Functional Consequences upon Mutation

    Directory of Open Access Journals (Sweden)

    Majid Masso

    2014-01-01

    Full Text Available The AUTO-MUTE 2.0 stand-alone software package includes a collection of programs for predicting functional changes to proteins upon single residue substitutions, developed by combining structure-based features with trained statistical learning models. Three of the predictors evaluate changes to protein stability upon mutation, each complementing a distinct experimental approach. Two additional classifiers are available, one for predicting activity changes due to residue replacements and the other for determining the disease potential of mutations associated with nonsynonymous single nucleotide polymorphisms (nsSNPs in human proteins. These five command-line driven tools, as well as all the supporting programs, complement those that run our AUTO-MUTE web-based server. Nevertheless, all the codes have been rewritten and substantially altered for the new portable software, and they incorporate several new features based on user feedback. Included among these upgrades is the ability to perform three highly requested tasks: to run “big data” batch jobs; to generate predictions using modified protein data bank (PDB structures, and unpublished personal models prepared using standard PDB file formatting; and to utilize NMR structure files that contain multiple models.

  11. The role of brand image congruity in Iranian consumers’ demand for auto parts

    Directory of Open Access Journals (Sweden)

    Naser Azad

    2014-06-01

    Full Text Available One of the primary issues in handling demands for auto parts in the world is to build a mutual trust between consumers and vendors. When people trust a brand, they purchase more easily and it is possible to develop market. In Iran, there is a growing interest in demand for auto parts and each year, tens of millions of auto parts are getting sold. This paper presents an empirical investigation to detect the effects of brand image on demand for auto parts. Using a sample of 202 randomly selected people who buy/sell auto parts in city of Tehran, Iran, the study determines three variables including brand strength, brand attributes and consumer trust through the implementation of structural equation modeling.

  12. Calibration transfer via an extreme learning machine auto-encoder.

    Science.gov (United States)

    Chen, Wo-Ruo; Bin, Jun; Lu, Hong-Mei; Zhang, Zhi-Min; Liang, Yi-Zeng

    2016-03-21

    In order to solve the spectra standardization problem in near-infrared (NIR) spectroscopy, a Transfer via Extreme learning machine Auto-encoder Method (TEAM) has been proposed in this study. A comparative study among TEAM, piecewise direct standardization (PDS), generalized least squares (GLS) and calibration transfer methods based on canonical correlation analysis (CCA) was conducted, and the performances of these algorithms were benchmarked with three spectral datasets: corn, tobacco and pharmaceutical tablet spectra. The results show that TEAM is a stable method and can significantly reduce prediction errors compared with PDS, GLS and CCA. TEAM can also achieve the best RMSEPs in most cases with a small number of calibration sets. TEAM is implemented in Python language and available as an open source package at https://github.com/zmzhang/TEAM.

  13. Auto antibodies against oxidized low density lipoprotein in severe preeclampsia.

    Science.gov (United States)

    Jain, Meenakshi; Sawhney, Harjeet; Aggarwal, Neelam; Vashistha, Kala; Majumdhar, Siddarth

    2004-06-01

    To study autoantibody titres against oxidized low density lipoprotein in preeclamsia. Ten millimeters of heparinized blood samples were collected from 20 primigravidae with severe preeclamsia (study group) and 20 gestation-matched normotensive primigravidae (control group). Concentration of malondialdehyde, metabolite of lipid peroxidation were measured in sera by HPLC and autoantibodies against oxidized low density lipoproteins (obtained after oxidation with 2 mm CuSO(4)) were determined by ELISA. Statistical analysis was performed by Student's t-test and chi(2) test. Mean triglyceride levels were significantly (P /=1.32). In preeclamptic women, diastolic blood pressure, the amount of urinary protein excretion and the plasma level of urea were significantly higher (P < 0.05) in patients with higher auto antibody titre. Titres of autoantibodies to oxidized low density lipoprotein were similar in normotensive and preeclamptic women. In preeclamptic women, titres correlated positively with the severity of preeclampsia.

  14. Auto-adjusting of the gap at electro erosion processing

    Science.gov (United States)

    Rusnac, V.; Topala, P.; Guzgan, D.; Poperecinii, A.

    2017-08-01

    In this paper the authors studied the mechanism of materials’ erosion when applying pulsed electrical discharge machining (PEDM) during the dimensional processing and the formation of deposition layers. It is known that during the processing the tool-electrode wear occurs. The practical part of the paper is of particular interest that describes design and the construction of a device intended for auto-adjusting of the gap size at the processing by applying PEDM. As a result, there is a stable amount of power released in the interstitial space, to avoid uncontrolled wear of the tool-electrode, for the homogeneous processing, free from defects leading to an increase in dimensional processing precision.

  15. A Novel Auto-Sorting System for Chinese Cabbage Seeds

    Directory of Open Access Journals (Sweden)

    Kuo-Yi Huang

    2017-04-01

    Full Text Available This paper presents a novel machine vision-based auto-sorting system for Chinese cabbage seeds. The system comprises an inlet-outlet mechanism, machine vision hardware and software, and control system for sorting seed quality. The proposed method can estimate the shape, color, and textural features of seeds that are provided as input neurons of neural networks in order to classify seeds as “good” and “not good” (NG. The results show the accuracies of classification to be 91.53% and 88.95% for good and NG seeds, respectively. The experimental results indicate that Chinese cabbage seeds can be sorted efficiently using the developed system.

  16. YASMINA REZA, OU LE SERVICE MINIMUM AUTO/BIOGRAPHIQUE

    Directory of Open Access Journals (Sweden)

    Hélène Jaccomard

    2009-12-01

    Full Text Available Yasmina Reza, dramaturge de renommée mondiale, a écrit d’autres types de textes que des pièces de théâtre. Notamment, deux recueils, Hammerklavier en 1997, puis Nulle part en 2005. Il s’agira de justifier la nature «auto/biographique » de ces fragments anecdotiques et philosophiques, car la narratrice, d’après elle, bien qu’étant l’héroïne de son texte, ne raconte ni sa vie privée, ni son enfance située ‘nulle part’. Reza se rattache donc à une conception du genre, comme étant non-réaliste, non-totalisant. Les deux recueils s’apparentent tout à la fois à de l’autofiction, de l’autocritique et de l’autoréflexion.

  17. [Value of positive auto controls in the gel centrifugation method].

    Science.gov (United States)

    Eichler, H; Kretschmer, V

    1994-01-01

    We studied 97 samples of patients being positive in the autocontrol of the indirect antiglobulin test (IAT) in the gel system (DiaMed). In 83.2%, retesting with monospecific anti-IgG serum gave also positive results, due to a specific phenomenon caused, for example, by drug-specific antibodies (AB), warm auto-AB or allo-AB. In contrast, only 52.9% of the samples retested by the standard tube technique with polyspecific antiglobulin serum reacted positive. Only in 6 patients slightly increased cold agglutinins could be detected. None of the investigated patients showed any clinical or laboratory signs of hemolysis except one with pernicious anemia. We conclude that positive results of the autocontrol in the gel IAT should be confirmed by an additional DAT in the tube technique. If this second test shows a negative result, transfusions can take place without any restrictions.

  18. Sähköauto : Akkujärjestelmä

    OpenAIRE

    Nykänen, Veikko

    2014-01-01

    Työn tavoitteena oli muokata vanhasta polttomoottorillisesta henkilöautosta täyssähköauto esittely- ja kaupunkiautoksi. Autolle asetettavia tavoitteita olivat, että auton pystyi lataamaan sähköverkon lisäksi koulun omaa tuuli- ja aurinkovoimaa käyttäen, autolla piti saavuttaa 120 km toimintasäde sekä autosta piti saada mahdollisimman käyttöturvallinen. Työssä käytettiin paljon täyssähköautomuunnoksesta käsiteltäviä materiaaleja ja dokumentteja, kuten opinnäytetöitä ja foorumikeskusteluita...

  19. Administration of the adrenaline auto-injector at the nursery/kindergarten/school in Western Japan.

    Science.gov (United States)

    Korematsu, Seigo; Fujitaka, Michiko; Ogata, Mika; Zaitsu, Masafumi; Motomura, Chikako; Kuzume, Kazuyo; Toku, Yuchiro; Ikeda, Masanori; Odajima, Hiroshi

    2017-01-01

    In view of the increasing prevalence of food allergies, there has been an associated increase in frequency of situations requiring an emergency response for anaphylaxis at the home, childcare facilities and educational institutions. To clarify the situation of adrenaline auto-injector administration in nursery/kindergarten/school, we carried out a questionnaire survey on pediatric physicians in Western Japan. In 2015, self-reported questionnaires were mailed to 421 physicians who are members of the West Japan Research Society Pediatric Clinical Allergy and Shikoku Research Society Pediatric Clinical Allergy. The response rate was 44% (185 physicians) where 160 physicians had a prescription registration for the adrenaline auto-injector. In the past year, 1,330 patients were prescribed the adrenaline auto-injector where 83 patients (6% of the prescribed patients) actually administered the adrenaline auto-injector, of which 14 patients (17% of the administered patients) self-administered the adrenaline auto-injector. "Guardians" at the nursery/kindergarten and elementary school were found to have administered the adrenaline auto-injector the most. Among 117 adrenaline auto-injector prescription-registered physicians, 79% had experienced nonadministration of adrenaline auto-injector at nursery/kindergarten/school when anaphylaxis has occurred. The most frequent reason cited for not administering the adrenaline auto-injector was "hesitation about the timing of administration." If the adrenaline auto-injector was administered after the guardian arrived at the nursery/kindergarten/school, it may lead to delayed treatment of anaphylaxis in which symptoms develop in minutes. Education and cooperation among physicians and nursery/kindergarten/school staff will reduce the number of children suffering unfortunate outcomes due to anaphylaxis.

  20. The auto-amputated adnexa: a review of findings in a pediatric population.

    Science.gov (United States)

    Focseneanu, Mariel A; Omurtag, Kenan; Ratts, Valerie S; Merritt, Diane F

    2013-12-01

    To quantify our experience and that of the literature with diagnosis and management of the auto-amputated adnexa in a pediatric population. Case series and literature review. Tertiary care medical center. Case series of pediatric patients (auto-amputation collected from our medical center and the literature. None. Auto-amputated adnexa. In addition to the 3 cases discussed from our institution, 91 cases of auto-amputated adnexa were identified in the literature dating back to 1943, for a total of 94 cases. Forty-nine percent (46/94) of the cases involved girls in a pediatric population (auto-amputated adnexa. 34 out of 46 cases were analyzed in detail. The right adnexa were involved in 56% of the cases. The most common presenting complaint verbalized by the older girls was pain; however, 8 cases were identified in asymptomatic girls undergoing unrelated diagnostic testing. The auto-amputated adnexa is a rare finding in the pediatric population, but it must be considered as a possible explanation for the incidental finding of absence of the fallopian tube or ovary in the subgroup of patients who undergo surgery for any reason. Patients with an antecedent history of pelvic pain either chronic or intermittent in nature may be diagnosed with torsion or less frequently auto-amputation of the adnexa. A fetal "pelvic mass" or "ovarian cyst" may predispose the adnexa to torsion and subsequent auto-amputation either in-utero or post-delivery. Many of these antenatally diagnosed cysts and even subsequent auto-amputations are completely asymptomatic, however, and do not compromise fertility assuming the contralateral adnexa are normal. Thus expectant management is appropriate for small (less than 4 cm), asymptomatic simple cysts and even suspected auto-amputated adnexa in an asymptomatic patient. Copyright © 2013 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

  1. Workshop on coatings needs in the auto industry

    Energy Technology Data Exchange (ETDEWEB)

    Courtright, E L

    1993-05-01

    New lightweight materials continue to be of great interest to the automotive industry. Compared to 20 years ago, the average vehicle weight has been reduced by almost a fourth, and fuel economy has nearly doubled. While continued improvements are both desirable and possible, materials choices are narrowing and the manufacturing methods needed to produce advanced materials systems are much more costly. The incentives remain high, however; particularly in view of large payoffs associated with minimizing structural weight in electric and hybrid-type vehicles. One generic solution is to develop coatings that will enable the use of lower cost materials. A workshop on coatings needs in the auto industry was held in Detroit, Michigan on October 27 and 28, 1992 with the objective of identifying research needs where coatings could enhance the use of energy efficient lightweight materials for automotive applications. Four generic areas had previously been identified auto manufacturers and industry suppliers. These were: Wear Coatings, Hard Protective Coatings for Plastics, Solar Control Coatings, and Process Manufacturing Issues. The development of coatings and coating technologies for lightweight metals and metal matrix composites emerged as the number one research needs. This need underscores the interest in making better use of existing lightweight metals, e.g. magnesium, aluminum, and their alloys. Coatings to protect plastics and reinforced plastic composites were also identified as a major area of importance. Protection from automotive liquids and gases. Coatings that will improve mar resistance, resist UV degradation, or eliminate degradation due to moisture absorption are also needed. Accordingly, manufacturability issues associated with coating light metals, e.g. aluminum, magnesium, and metal matrix composites with wear and corrosion resistant materials, were identified as a high priority research need.

  2. Cross-sectional and Quasi-panel Explorations of the Connection between the Built Environment and Auto Ownership

    OpenAIRE

    Cao, Xinyu; Mokhtarian, Patricia L; Handy, Susan L.

    2007-01-01

    Auto ownership is a critical mediating link in the connection between the built environment and travel behavior: the built environment presumably influences auto ownership, which in turn impacts travel behavior. However, the way in which individual elements of the built environment affect auto ownership choices is far from understood. Further, residential self-selection may confound the interaction between the built environment and auto ownership. And the absence of panel data impedes our und...

  3. The Performance of Several Docking Programs at Reproducing Protein–Macrolide-Like Crystal Structures

    Directory of Open Access Journals (Sweden)

    Alejandro Castro-Alvarez

    2017-01-01

    Full Text Available The accuracy of five docking programs at reproducing crystallographic structures of complexes of 8 macrolides and 12 related macrocyclic structures, all with their corresponding receptors, was evaluated. Self-docking calculations indicated excellent performance in all cases (mean RMSD values ≤ 1.0 and confirmed the speed of AutoDock Vina. Afterwards, the lowest-energy conformer of each molecule and all the conformers lying 0–10 kcal/mol above it (as given by Macrocycle, from MacroModel 10.0 were subjected to standard docking calculations. While each docking method has its own merits, the observed speed of the programs was as follows: Glide 6.6 > AutoDock Vina 1.1.2 > DOCK 6.5 >> AutoDock 4.2.6 > AutoDock 3.0.5. For most of the complexes, the five methods predicted quite correct poses of ligands at the binding sites, but the lower RMSD values for the poses of highest affinity were in the order: Glide 6.6 ≈ AutoDock Vina ≈ DOCK 6.5 > AutoDock 4.2.6 >> AutoDock 3.0.5. By choosing the poses closest to the crystal structure the order was: AutoDock Vina > Glide 6.6 ≈ DOCK 6.5 ≥ AutoDock 4.2.6 >> AutoDock 3.0.5. Re-scoring (AutoDock 4.2.6//AutoDock Vina, Amber Score and MM-GBSA improved the agreement between the calculated and experimental data. For all intents and purposes, these three methods are equally reliable.

  4. What factors affect the carriage of epinephrine auto-injectors by teenagers?

    Directory of Open Access Journals (Sweden)

    Macadam Clare

    2012-02-01

    Full Text Available Abstract Background Teenagers with allergies are at particular risk of severe and fatal reactions, but epinephrine auto-injectors are not always carried as prescribed. We investigated barriers to carriage. Methods Patients aged 12-18 years old under a specialist allergy clinic, who had previously been prescribed an auto-injector were invited to participate. Semi-structured interviews explored the factors that positively or negatively impacted on carriage. Results Twenty teenagers with food or venom allergies were interviewed. Only two patients had used their auto-injector in the community, although several had been treated for severe reactions in hospital. Most teenagers made complex risk assessments to determine whether to carry the auto-injector. Most but not all decisions were rational and were at least partially informed by knowledge. Factors affecting carriage included location, who else would be present, the attitudes of others and physical features of the auto-injector. Teenagers made frequent risk assessments when deciding whether to carry their auto-injectors, and generally wanted to remain safe. Their decisions were complex, multi-faceted and highly individualised. Conclusions Rather than aiming for 100% carriage of auto-injectors, which remains an ambitious ideal, personalised education packages should aim to empower teenagers to make and act upon informed risk assessments.

  5. What factors affect the carriage of epinephrine auto-injectors by teenagers?

    Science.gov (United States)

    Macadam, Clare; Barnett, Julie; Roberts, Graham; Stiefel, Gary; King, Rosemary; Erlewyn-Lajeunesse, Michel; Holloway, Judith A; Lucas, Jane S

    2012-02-02

    Teenagers with allergies are at particular risk of severe and fatal reactions, but epinephrine auto-injectors are not always carried as prescribed. We investigated barriers to carriage. Patients aged 12-18 years old under a specialist allergy clinic, who had previously been prescribed an auto-injector were invited to participate. Semi-structured interviews explored the factors that positively or negatively impacted on carriage. Twenty teenagers with food or venom allergies were interviewed. Only two patients had used their auto-injector in the community, although several had been treated for severe reactions in hospital. Most teenagers made complex risk assessments to determine whether to carry the auto-injector. Most but not all decisions were rational and were at least partially informed by knowledge. Factors affecting carriage included location, who else would be present, the attitudes of others and physical features of the auto-injector. Teenagers made frequent risk assessments when deciding whether to carry their auto-injectors, and generally wanted to remain safe. Their decisions were complex, multi-faceted and highly individualised. Rather than aiming for 100% carriage of auto-injectors, which remains an ambitious ideal, personalised education packages should aim to empower teenagers to make and act upon informed risk assessments.

  6. Drug-device combination products in the twenty-first century: epinephrine auto-injector development using human factors engineering.

    Science.gov (United States)

    Edwards, Eric S; Edwards, Evan T; Simons, F Estelle R; North, Robert

    2015-05-01

    The systematic application of human factors engineering (HFE) principles to the development of drug-device combination products, including epinephrine auto-injectors (EAIs), has the potential to improve the effectiveness and safety of drug administration. A PubMed search was performed to assess the role of HFE in the development of drug-device combination products. The following keywords were used in different combinations: 'human factors engineering,' 'human factors,' 'medical products,' 'epinephrine/adrenaline auto-injector,' 'healthcare' and 'patient safety.' This review provides a summary of HFE principles and their application to the development of drug-device combination products as advised by the US FDA. It also describes the HFE process that was applied to the development of Auvi-Q, a novel EAI, highlighting specific steps that occurred during the product-development program. For drug-device combination products, device labeling and usability are critical and have the potential to impact clinical outcomes. Application of HFE principles to the development of drug-delivery devices has the potential to improve product quality and reliability, reduce risk and improve patient safety when applied early in the development process. Additional clinical and real-world studies will confirm whether the application of HFE has helped to develop an EAI that better meets the needs of patients at risk of anaphylaxis.

  7. Up and Running with AutoCAD 2011 2D and 3D Drawing and Modeling

    CERN Document Server

    Gindis, Elliot

    2010-01-01

    Gindis introduces AutoCAD with step by step instructions, stripping away complexities to  begin working in AutoCAD immediately.  All concepts are explained first in theory, and then shown in practice, helping the reader understand what it is they are doing and why, before they do it. Divided into three parts, the book covers beginning through advanced AutoCAD, including 3D features.  Also included is an extensive Appendix for each part, detailing additional useful CAD-related information not often found in other text books The book contains supporting graphics (screen shot

  8. Up and Running with AutoCAD 2012 2D and 3D Drawing and Modeling

    CERN Document Server

    Gindis, Elliot

    2011-01-01

    Gindis introduces AutoCAD with step by step instructions, stripping away complexities to  begin working in AutoCAD immediately.  All concepts are explained first in theory, and then shown in practice, helping the reader understand what it is they are doing and why, before they do it. Divided into three parts, the book covers beginning through advanced AutoCAD, including 3D features.  Also included is an extensive Appendix for each part, detailing additional useful CAD-related information not often found in other text books The book contains supporting graphics (screen shot

  9. Discribing the Auto-Ignition Quality of Fuels in HCCI Engines

    OpenAIRE

    Risberg, Per

    2006-01-01

    The Homogeneous Charge Compression Ignition (HCCI) engine is a promising engine concept that emits low concentrations of NOx and particulates and still has a high efficiency. Since the charge is auto-ignited, the auto-ignition quality of the fuel is of major importance. It has been shown in several studies that neither of the classical measures of auto-ignition quality of gasoline-like fuels, RON and MON, can alone describe this in all conditions in HCCI combustion. However, even in such case...

  10. Introduction to AutoCAD 2013 2D and 3D design

    CERN Document Server

    Yarwood, Alf

    2013-01-01

    Master the complexities of the world's bestselling 2D and 3D software with Alf Yarwood's Introduction to AutoCAD 2013. Ideally suited to new users of AutoCAD, this book will be a useful resource for drawing modules in both vocational and introductory undergraduate courses in engineering and construction.Alf Yarwood has once again produced a comprehensive, step-by-step introduction to the latest release of AutoCAD. Covering all the basic principles and acting as an introduction to 2D drawing, it also contains extensive coverage of all 3D topics, including 3D solid modelling a

  11. Una voz temblorosa: Música y auto-afección en Jacques Derrida

    OpenAIRE

    Cristóbal Durán

    2015-01-01

    El presente artículo busca mostrar que el estatuto de la música en la obra de Jacques Derrida propone una problematización rigurosa de la figura de la auto-afección. Si esta última encuentra en la voz su modelo ejemplar, en tanto espacio en el cual un sí-mismo garantiza la estabilidad de su presencia, la formulación derrideana de la música como experiencia de una apropiación imposible sugiere una reformulación de la voz auto-afectiva. La auto-afección, como posibilidad de una subjetividad, ya...

  12. Up and running with AutoCAD 2013 2D and 3D drawing and modeling

    CERN Document Server

    Gindis, Elliot

    2012-01-01

    Gindis introduces AutoCAD with step by step instructions, stripping away complexities to  begin working in AutoCAD immediately.  All concepts are explained first in theory, and then shown in practice, helping the reader understand what it is they are doing and why, before they do it. Divided into three parts, the book covers beginning through advanced AutoCAD, including 3D features.  Also included is an extensive Appendix for each part, detailing additional useful CAD-related information not often found in other text books The book contains support

  13. Feedback circuit design of an auto-gating power supply for low-light-level image intensifier

    Science.gov (United States)

    Yang, Ye; Yan, Bo; Zhi, Qiang; Ni, Xiao-bing; Li, Jun-guo; Wang, Yu; Yao, Ze

    2015-11-01

    This paper introduces the basic principle of auto-gating power supply which using a hybrid automatic brightness control scheme. By the analysis of current as image intensifier to special requirements of auto-gating power supply, a feedback circuit of the auto-gating power supply is analyzed. Find out the reason of the screen flash after the auto-gating power supply assembled image intensifier. This paper designed a feedback circuit which can shorten the response time of auto-gating power supply and improve screen slight flicker phenomenon which the human eye can distinguish under the high intensity of illumination.

  14. A persuasão no discurso de auto-ajuda: uma abordagem sistêmico-funcional

    OpenAIRE

    Loli, Rejane

    2008-01-01

    Os livros de auto-ajuda constituem um dos segmentos com maior crescimento e é também o responsável pelos novos best-sellers do mercado. O instituto de pesquisas Marketdata estima que o mercado mundial da auto-ajuda movimentou cerca de US$8.5 bilhões em 2003. Eles estimam que o tamanho total desse mercado pode alcançar mais de US$11 bilhões em 2008. Notemos que o auto de auto-ajuda, tal como em auto-didata, significa aprendizagem sem o acompanhamento de um mestre. Não quer dizer que a pessoa...

  15. Methods of In-Process On-Machine Auto-Inspection of Dimensional Error and Auto-Compensation of Tool Wear for Precision Turning

    Directory of Open Access Journals (Sweden)

    Shih-Ming Wang

    2016-04-01

    Full Text Available The purpose of this study is mainly to develop an information and communication technology (ICT-based intelligent dimension inspection and tool wear compensation method for precision tuning. With the use of vibration signal processing/characteristics analysis technology combined with ICT, statistical analysis, and diagnosis algorithms, the method can be used to proceed with an on-line dimension inspection and on-machine tool wear auto-compensation for the turning process. Meanwhile, the method can also monitor critical tool life to identify the appropriate time for cutter replacement to reduce machining costs and improve the production efficiency of the turning process. Compared to the traditional ways, the method offers the advantages of requiring less manpower, and having better production efficiency, high tool life, fewer scrap parts, and low costs for inspection instruments. Algorithms and diagnosis threshold values for the detection, cutter wear compensation, and cutter life monitoring were developed. In addition, a bilateral communication module utilizing FANUC Open CNC (computer numerical control Application Programming Interface (API Spec was developed for the on-line extraction of instant NC (numerical control codes for monitoring and transmit commands to CNC controllers for cutter wear compensation. With use of local area networks (LAN to deliver the detection and correction information, the proposed method was able to remotely control the on-machine monitoring process and upload the machining and inspection data to a remote central platform for further production optimization. The verification experiments were conducted on a turning production line. The results showed that the system provided 93% correction for size inspection and 100% correction for cutter wear compensation.

  16. Rotary Percussive Auto-Gopher for Deep Drilling and Sampling

    Science.gov (United States)

    Bar-Cohen, Yoseph; Badescu, Mircea; Sherrit, Stewart

    2009-01-01

    The term "rotary percussive auto-gopher" denotes a proposed addition to a family of apparatuses, based on ultrasonic/ sonic drill corers (USDCs), that have been described in numerous previous NASA Tech Briefs articles. These apparatuses have been designed, variously, for boring into, and/or acquiring samples of, rock or other hard, brittle materials of geological interest. In the case of the rotary percussive autogopher, the emphasis would be on developing an apparatus capable of penetrating to, and acquiring samples at, depths that could otherwise be reached only by use of much longer, heavier, conventional drilling-and-sampling apparatuses. To recapitulate from the prior articles about USDCs: A USDC can be characterized as a lightweight, low-power jackhammer in which a piezoelectrically driven actuator generates ultrasonic vibrations and is coupled to a tool bit through a free mass. The bouncing of the free mass between the actuator horn and the drill bit converts the actuator ultrasonic vibrations into sonic hammering of the drill bit. The combination of ultrasonic and sonic vibrations gives rise to a hammering action (and a resulting chiseling action at the tip of the tool bit) that is more effective for drilling than is the microhammering action of ultrasonic vibrations alone. The hammering and chiseling actions are so effective that the size of the axial force needed to make the tool bit advance into soil, rock, or another material of interest is much smaller than in ordinary rotary drilling, ordinary hammering, or ordinary steady pushing. The predecessor of the rotary percussive auto-gopher is an apparatus, now denoted an ultrasonic/sonic gopher and previously denoted an ultrasonic gopher, described in "Ultrasonic/ Sonic Mechanism for Drilling and Coring" (NPO-30291), NASA Tech Briefs Vol. 27, No. 9 (September 2003), page 65. The ultrasonic/sonic gopher is intended for use mainly in acquiring cores. The name of the apparatus reflects the fact that, like a

  17. Doenças auto-imunes da tiróide: associação com gastrite auto-imune

    OpenAIRE

    Marinho, Ana Sofia santos

    2013-01-01

    As patologias auto-imunes da tiróide, incluindo tiroidite linfocítica crónica e doença de Graves, são doenças auto-imunes específicas de órgão, caracterizadas por infiltração linfocítica da tiróide. Auto-anticorpos contra antigénios da tiróide (anticorpos anti-peroxidase tiroideia, anti-tiroglobulina e anti-receptor da tirotropina), são frequentemente encontrados no soro dos doentes. A gastrite atrófica é uma alteração que afecta a mucosa corporal e quando associada com anemia perniciosa é...

  18. Morbidity of total pancreatectomy with islet cell auto-transplantation compared to total pancreatectomy alone.

    Science.gov (United States)

    Bhayani, Neil H; Enomoto, Laura M; Miller, Jennifer L; Ortenzi, Gail; Kaifi, Jussuf T; Kimchi, Eric T; Staveley-O'Carroll, Kevin F; Gusani, Niraj J

    2014-06-01

    In pancreatitis, total pancreatectomy (TP) is an effective treatment for refractory pain. Islet cell auto-transplantation (IAT) may mitigate resulting endocrinopathy. Short-term morbidity data for TP + IAT and comparisons with TP are limited. This study, using 2005-2011 National Surgical Quality Improvement Program data, examined patients with pancreatitis or benign neoplasms. Morbidity after TP alone was compared with that after TP + IAT. In 126 patients (40%) undergoing TP and 191 (60%) patients undergoing TP + IAT, the most common diagnosis was chronic pancreatitis. Benign neoplasms were present in 46 (14%) patients, six of whom underwent TP + IAT. Patients in the TP + IAT group were younger and had fewer comorbidities than those in the TP group. Despite this, major morbidity was more frequent after TP + IAT than after TP [n = 79 (41%) versus n = 36 (29%); P = 0.020]. Transfusions were more common after TP + IAT [n = 39 (20%) versus n = 9 (7%); P = 0.001], as was longer hospitalization (13 days versus 9 days; P < 0.0001). There was no difference in mortality. This study is the only comparative, multicentre study of TP and TP + IAT. The TP + IAT group experienced higher rates of major morbidity and transfusion, and longer hospitalizations. Better data on the longterm benefits of TP + IAT are needed. In the interim, this study should inform physicians and patients regarding the perioperative risks of TP + IAT. © 2013 International Hepato-Pancreato-Biliary Association.

  19. Advanced High Strength Steel in Auto Industry: an Overview

    Directory of Open Access Journals (Sweden)

    N. Baluch

    2014-08-01

    Full Text Available The world’s most common alloy, steel, is the material of choice when it comes to making products as diverse as oil rigs to cars and planes to skyscrapers, simply because of its functionality, adaptability, machine-ability and strength. Newly developed grades of Advanced High Strength Steel (AHSS significantly outperform competing materials for current and future automotive applications. This is a direct result of steel’s performance flexibility, as well as of its many benefits including low cost, weight reduction capability, safety attributes, reduced greenhouse gas emissions and superior recyclability. To improve crash worthiness and fuel economy, the automotive industry is, increasingly, using AHSS. Today, and in the future, automotive manufacturers must reduce the overall weight of their cars. The most cost-efficient way to do this is with AHSS. However, there are several parameters that decide which of the AHSS types to be used; the most important parameters are derived from the geometrical form of the component and the selection of forming and blanking methods. This paper describes the different types of AHSS, highlights their advantages for use in auto metal stampings, and discusses about the new challenges faced by stampers, particularly those serving the automotive industry.

  20. Sepsis Patient Detection and Monitor Based on Auto-BN.

    Science.gov (United States)

    Jiang, Yu; Sha, Lui; Rahmaniheris, Maryam; Wan, Binhua; Hosseini, Mohammad; Tan, Pengliu; Berlin, Richard B

    2016-04-01

    Sepsis is a life-threatening condition caused by an inappropriate immune response to infection, and is a leading cause of elderly death globally. Early recognition of patients and timely antibiotic therapy based on guidelines improve survival rate. Unfortunately, for those patients, it is often detected late because it is too expensive and impractical to perform frequent monitoring for all the elderly. In this paper, we present a risk driven sepsis screening and monitoring framework to shorten the time of onset detection without frequent monitoring of all the elderly. Within this framework, the sepsis ultimate risk of onset probability and mortality is calculated based on a novel temporal probabilistic model named Auto-BN, which consists of time dependent state, state dependent property, and state dependent inference structures. Then, different stages of a patient are encoded into different states, monitoring frequency is encoded into the state dependent property, and screening content is encoded into different state dependent inference structures. In this way, the screening and monitoring frequency and content can be automatically adjusted when encoding the sepsis ultimate risk into the guard of state transition. This allows for flexible manipulation of the tradeoff between screening accuracy and frequency. We evaluate its effectiveness through empirical study, and incorporate it into existing medical guidance system to improve medical healthcare.

  1. Investigation of Auto-ignition of Several Single Fuels

    Directory of Open Access Journals (Sweden)

    Firmansyaha

    2014-07-01

    Full Text Available HCCI operating principals have been widely investigated yet the uncontrollable combustion of HCCI is the major obstacle in its development. This paper is trying to increase the understanding on the auto-ignition and combustion process of several fuels to be applied in HCCI combustion system. The investigation includes the combustion behavior of 4 fuels, gasoline (RON95, diesel, n-heptane, isooctane, The investigation was done in constant volume chamber with elevated temperature (800°C. Four lambdas were tested for each fuel namely 0.8, 1, 1.2 and 2. It is found that these fuels can be categorized into two major categories based on combustion characteristics, homogeneous and diffusive combustion. Gasoline and isooctane, homogeneous combustion, shows almost the same behavior where the increase in lambda will increase the combustion delay even though isooctane shows much longer delayed compared to gasoline. While diesel and n-heptane, diffusive combustion, has no ignition delay yet showing different behavior on the later parts of the combustion where diesel effecting 10-90% combustion stage while n-heptane on 90-100%.

  2. Dissolution of Metal Supported Spent Auto Catalysts in Acids

    Directory of Open Access Journals (Sweden)

    Fornalczyk A.

    2016-03-01

    Full Text Available Metal supported auto catalysts, have been used in sports and racing cars initially, but nowadays their application systematically increases. In Metal Substrate (supported Converters (MSC, catalytic functions are performed by the Platinum Group Metals (PGM: Pt, Pd, Rh, similarly to the catalysts on ceramic carriers. The contents of these metals make that spent catalytic converters are valuable source of precious metals. All over the world there are many methods for the metals recovery from the ceramic carriers, however, the issue of platinum recovery from metal supported catalysts has not been studied sufficiently yet. The paper presents preliminary results of dissolution of spent automotive catalyst on a metal carrier by means of acids: H2SO4, HCl, HNO3, H3PO4. The main assumption of the research was the dissolution of base metals (Fe, Cr, Al from metallic carrier of catalyst, avoiding dissolution of PGMs. Dissolution was the most effective when concentrated hydrochloric acid, and 2M sulfuric acid (VI was used. It was observed that the dust, remaining after leaching, contained platinum in the level of 0.8% and 0.7%, respectively.

  3. Noise exposure levels in stock car auto racing.

    Science.gov (United States)

    Rose, Austin S; Ebert, Charles S; Prazma, Jiri; Pillsbury, Harold C

    2008-12-01

    Noise-induced hearing loss associated with the workplace has been well described. Far less is known, however, about the risks to hearing from recreational sources of noise. We investigated the popular sport of stock car racing as a potentially significant source of noise exposure, and we conducted a sound-level survey at a National Association for Stock Car Auto Racing (NASCAR) event. Noise levels measured during the race ranged from 96.5 to 104 dB(A) at 46 meters ( approximately 150 feet) from the track and 99 to 109 dB(A) at 6 meters ( approximately 20 feet) from the track. The peak sound pressure level at 6 meters was 109 dB(A). Although significantly less than that associated with an immediate permanent threshold shift, such an exposure could cause a temporary threshold shift. Alhough hearing protection is recommended, particularly for track employees with longer periods of exposure, racing fans with only occasional exposure to such noise levels are unlikely to develop a permanent noise-induced hearing loss.

  4. Basal forebrain thermoregulatory mechanism modulates auto-regulated sleep

    Directory of Open Access Journals (Sweden)

    Hruda N Mallick

    2012-06-01

    Full Text Available Regulation of body temperature and sleep are two physiological mechanisms that are vital for our survival. Interestingly neural structures implicated in both these functions are common. These areas include the medial preoptic area, the lateral preoptic area, the ventrolateral preoptic area, the median preoptic nucleus and the medial septum, which form part of the basal forebrain.When given a choice, rats prefer to stay at an ambient temperature of 270C, though the maximum sleep was observed when they were placed at 300C. Ambient temperature around 270C should be considered as the thermoneutral temperature for rats in all sleep studies. At this temperature the diurnal oscillations of sleep and body temperature are properly expressed. The warm sensitive neurons of the preoptic area mediate the increase in sleep at 300C. Promotion of sleep during the rise in ambient temperature from 270C to 300C, serve a thermoregulatory function. Autonomous thermoregulatory changes in core body temperature and skin temperature could act as an input signal to modulate neuronal activity in sleep-promoting brain areas. The studies presented here show that the neurons of the basal forebrain play a key role in regulating sleep. Basal forebrain thermoregulatory system is a part of the global homeostatic sleep regulatory mechanism, which is auto-regulated.

  5. An auto-locked diode laser system for precision metrology

    Science.gov (United States)

    Beica, H. C.; Carew, A.; Vorozcovs, A.; Dowling, P.; Pouliot, A.; Barron, B.; Kumarakrishnan, A.

    2017-05-01

    We present a unique external cavity diode laser system that can be auto-locked with reference to atomic and molecular spectra. The vacuum-sealed laser head design uses an interchangeable base-plate comprised of a laser diode and optical elements that can be selected for desired wavelength ranges. The feedback light to the laser diode is provided by a narrow-band interference filter, which can be tuned from outside the laser cavity to fineadjust the output wavelength in vacuum. To stabilize the laser frequency, the digital laser controller relies either on a pattern-matching algorithm stored in memory, or on first or third derivative feedback. We have used the laser systems to perform spectroscopic studies in rubidium at 780 nm, and in iodine at 633 nm. The linewidth of the 780-nm laser system was measured to be ˜500 kHz, and we present Allan deviation measurements of the beat note and the lock stability. Furthermore, we show that the laser system can be the basis for a new class of lidar transmitters in which a temperature-stabilized fiber-Bragg grating is used to generate frequency references for on-line points of the transmitter. We show that the fiber-Bragg grating spectra can be calibrated with reference to atomic transitions.

  6. MAMMOGRAM IMAGE SEGMENTATION USING AUTO ADAPTIVE FUZZY INDEX MEASURE

    Directory of Open Access Journals (Sweden)

    I. Laurence Aroquiaraj

    2011-08-01

    Full Text Available Breast Cancer involves the uncontrolled growth of abnormal cells that have mutated from normal tissues. A radiologist looks for certain signs and characteristics indicative of cancer when evaluating a mammogram. The main task is to obtain the locations of suspicious regions to assist radiologists in diagnosis. Image segmentation has been approached from a wide variety of perspectives: region-based approach, morphological operation, multi-scale analysis, fuzzy approaches and stochastic approaches have been used for mammogram image segmentation but with some limitations. In spite of the several methods available in the literature, image segmentation still a challenging problem in most of image processing applications. The challenge comes from the fuzziness of image objects and the overlapping of the different regions. In this paper we propose fast auto adaptive image segmentation algorithm for finding the optimal thresholds for segmenting gray scale images. The proposed method is based on fuzzy index which decreases the similarity between pixels increases. The system uses initial estimation of the parameters. The fuzzy subsets derived from the image histogram using weighted fuzzy entropy will shows the similar cost measure as in pixels of the same subset. Experimental results demonstrate the effectiveness of the proposed approach.

  7. Emociones auto-percibidas en las clases de educacion fisica en primaria

    National Research Council Canada - National Science Library

    Martinez-Lopez, Maria; Gil-Madrona, Pedro

    2015-01-01

    El presente trabajo ofrece los resultados y las principales conclusiones sobre el estudio de las emociones auto-percibidas que predominan en los alumnos y profesores en las clases de Educacion fisica...

  8. Optimal level of continuous positive airway pressure: Auto-CPAP titration versus predictive formulas

    Directory of Open Access Journals (Sweden)

    Nashwa Abdel Wahab

    2017-04-01

    Conclusions: Predictive formulas might be useful as an alternative to autoCPAP. The model of predictive formula derived from the present small sample of Egyptian patients with OSAHS should be validated on a larger sample size.

  9. An application of ANP for ranking different factors influencing on demand for auto parts

    Directory of Open Access Journals (Sweden)

    Ali Zarepour

    2014-04-01

    Full Text Available This paper presents an empirical investigation to study different factors influencing auto parts in different regions of Iran. The study has asked some experts who worked for the biggest auto parts supplier named SaipaYadak to express their insights about important factors influencing demand for auto parts in different region and their insights have grouped into four categories of parts related issues, weather conditions, regional as well as cultural factors. The study has been applied in five different regions of country including central, south, north, west and east. The study has used analytical network process (ANP to rank different factors and the results indicate that regional factors is the most important item followed by cultural issues, auto parts and weather conditions.

  10. The auto-Igusa zeta function of a plane curve singularity is rational

    OpenAIRE

    Stout, Andrew R.

    2015-01-01

    It is shown that the auto-Igusa zeta function of a plane curve singularity is rational. This gives a new criterion for a plane curve over an algebraically closed field of characteristic zero to be smooth at a point.

  11. Auto-Photography as Research Practice: Identity and Self-Esteem Research

    Directory of Open Access Journals (Sweden)

    Carey M. Noland

    2006-01-01

    Full Text Available This paper explores auto-photography as a form of research practice in the area of identity and self-esteem research. It allows researchers to capture and articulate the ways identity guides human action and thought. It involves the generation and examination of the static images that participants themselves believe best represent them. Auto-photography is an important tool for building bridges with marginalized groups in the research process, since it offers researchers a way to let participants speak for themselves. Furthermore, by using this method researchers can avoid exclusive reliance on survey questionnaires and other such research instruments that may be culturally biased. I present two research projects using auto-photography: one involving adolescent Latina girls and one involving Indian women. Based on the experience of these projects, I discuss auto-photography's importance in identity and self-esteem research. Finally, I discuss some of the benefits and challenges of working with this method.

  12. Interpolis SlimOpWeg-programma : de AutoModus-app : vragenlijstonderzoek naar het effect van een app om smartphonegebruik in de auto te verminderen.

    OpenAIRE

    Groot-Mesken, J. de Wijnen, W. Stelling-Konczak, A. & Commandeur, J.J.F.

    2017-01-01

    Interpolis SlimOpWeg programme: the AutoModus app; Survey into the effect of an app on reducing smartphone use while driving a car. Within the programme SlimOpWeg the Dutch insurance company Interpolis had a smartphone app developed. The purpose of this ‘AutoModus app’ is to help young drivers to reduce their smartphone use behind the wheel, as distraction by mobile phone use is a major road safety problem. Interpolis asked SWOV to investigate the effectiveness of two versions of the app: 1. ...

  13. Trader’s competence in the internationalization of producing and exporting auto parts vehicles company

    OpenAIRE

    Carlos Roberto Rodrigues; Paolo Edoardo Coti-Zelati; Davi Lucas Arruda de Araújo

    2015-01-01

    This research proposes an analysis about the capacity of the Trader on the internationalization of auto parts manufacturers and exporters. The goal of this study is to contribute to the knowledge and for the awareness of key managers of auto parts manufacturers and exporters, for the Automotive Aftermarket business, about the importance of hiring a qualified professional to manage this area. To that end, it was adopted a descriptive research of qualitative nature. By the end of this study, it...

  14. Use of individual auto-injector kits ?IZAS-05? on the contemporary battlefield

    OpenAIRE

    Ziemba, Rados?aw

    2012-01-01

    Summary In crisis situations, such as transportation catastrophes, terrorist attacks or contamination with chemical warfare agents, it is crucial to properly organize and sensibly conduct rescue operations. Among chemical warfare agents, the most toxic ones are the derivatives of organophosphorus compounds. An individual auto-injector kit ?IZAS-05? contains auto-injectors, which are devices designed for intramuscular administration of drugs in self-aid or buddy-aid on the battlefield. This pa...

  15. O auto-retrato na fotografia contemporânea : que resta do sujeito, tecnicamente falado?

    Directory of Open Access Journals (Sweden)

    Pot Eduarda Neves

    2011-01-01

    Full Text Available O auto-retrato na fotografia contemporânea. Da ilusão da semelhança da realidade à ilusão da representação da identidade. O paradoxo como categoria tensional do auto-retrato.Self-portrait in contemporary photography: from the illusion of realities’s resemblance to the illusion of identities’s representation. Paradox as self-portrait’s tensional category.

  16. Serum anti-BPAG1 auto-antibody is a novel marker for human melanoma.

    Directory of Open Access Journals (Sweden)

    Takashi Shimbo

    2010-05-01

    Full Text Available Malignant melanoma is one of the most aggressive types of tumor. Because malignant melanoma is difficult to treat once it has metastasized, early detection and treatment are essential. The search for reliable biomarkers of early-stage melanoma, therefore, has received much attention. By using a novel method of screening tumor antigens and their auto-antibodies, we identified bullous pemphigoid antigen 1 (BPAG1 as a melanoma antigen recognized by its auto-antibody. BPAG1 is an auto-antigen in the skin disease bullous pemphigoid (BP and anti-BPAG1 auto-antibodies are detectable in sera from BP patients and are used for BP diagnosis. However, BPAG1 has been viewed as predominantly a keratinocyte-associated protein and a relationship between BPAG1 expression and melanoma has not been previously reported. In the present study, we show that bpag1 is expressed in the mouse F10 melanoma cell line in vitro and F10 melanoma tumors in vivo and that BPAG1 is expressed in human melanoma cell lines (A375 and G361 and normal human melanocytes. Moreover, the levels of anti-BPAG1 auto-antibodies in the sera of melanoma patients were significantly higher than in the sera of healthy volunteers (p<0.01. Furthermore, anti-BPAG1 auto-antibodies were detected in melanoma patients at both early and advanced stages of disease. Here, we report anti-BPAG1 auto-antibodies as a promising marker for the diagnosis of melanoma, and we discuss the significance of the detection of such auto-antibodies in cancer biology and patients.

  17. Matched-pair analysis to compare the outcomes of a second salvage auto-SCT to systemic chemotherapy alone in patients with multiple myeloma who relapsed after front-line auto-SCT.

    Science.gov (United States)

    Yhim, H-Y; Kim, K; Kim, J S; Kang, H J; Kim, J-A; Min, C-K; Bae, S H; Park, E; Yang, D-H; Suh, C; Kim, M K; Mun, Y-C; Eom, H S; Shin, H J; Yoon, H-J; Kwon, J H; Lee, J H; Kim, Y S; Yoon, S-S; Kwak, J-Y

    2013-03-01

    The aims of this study were to investigate the outcomes of second salvage auto-SCT and to identify the impacts of a second auto-SCT compared with systemic chemotherapy alone on disease outcome. Data from 48 patients who underwent second auto-SCT were matched to 144 patients (1:3) who received systemic chemotherapy alone from the Korean Myeloma Registry. Groups were matched for nine potential prognostic factors and compared for treatment outcomes. The median age of matching-pairs at relapse was 55.5 years. A total of 156 patients (81%) received vincristine, doxorubicin and dexamethasone induction therapy before the first auto-SCT. Thirty-five patients (73%) in the second auto-SCT group received novel agent-based therapies before the second auto-SCT, and similar proportion in both groups received novel therapies after relapse of front-line auto-SCT. With a median follow-up of 55.3 months, patients who underwent a second auto-SCT had significantly better median OS (55.5 vs 25.4 months, P=0.035). In multivariate analysis for OS, auto-SCT, International Staging System III and salvage chemotherapy alone were independent predictors for worse OS. The outcomes of second auto-SCT appear to be superior to those of systemic chemotherapy alone. A randomized trial comparing both treatment strategies is required.

  18. Patterns of synchrony for feed-forward and auto-regulation feed-forward neural networks

    Science.gov (United States)

    Aguiar, Manuela A. D.; Dias, Ana Paula S.; Ferreira, Flora

    2017-01-01

    We consider feed-forward and auto-regulation feed-forward neural (weighted) coupled cell networks. In feed-forward neural networks, cells are arranged in layers such that the cells of the first layer have empty input set and cells of each other layer receive only inputs from cells of the previous layer. An auto-regulation feed-forward neural coupled cell network is a feed-forward neural network where additionally some cells of the first layer have auto-regulation, that is, they have a self-loop. Given a network structure, a robust pattern of synchrony is a space defined in terms of equalities of cell coordinates that is flow-invariant for any coupled cell system (with additive input structure) associated with the network. In this paper, we describe the robust patterns of synchrony for feed-forward and auto-regulation feed-forward neural networks. Regarding feed-forward neural networks, we show that only cells in the same layer can synchronize. On the other hand, in the presence of auto-regulation, we prove that cells in different layers can synchronize in a robust way and we give a characterization of the possible patterns of synchrony that can occur for auto-regulation feed-forward neural networks.

  19. Patterns of synchrony for feed-forward and auto-regulation feed-forward neural networks.

    Science.gov (United States)

    Aguiar, Manuela A D; Dias, Ana Paula S; Ferreira, Flora

    2017-01-01

    We consider feed-forward and auto-regulation feed-forward neural (weighted) coupled cell networks. In feed-forward neural networks, cells are arranged in layers such that the cells of the first layer have empty input set and cells of each other layer receive only inputs from cells of the previous layer. An auto-regulation feed-forward neural coupled cell network is a feed-forward neural network where additionally some cells of the first layer have auto-regulation, that is, they have a self-loop. Given a network structure, a robust pattern of synchrony is a space defined in terms of equalities of cell coordinates that is flow-invariant for any coupled cell system (with additive input structure) associated with the network. In this paper, we describe the robust patterns of synchrony for feed-forward and auto-regulation feed-forward neural networks. Regarding feed-forward neural networks, we show that only cells in the same layer can synchronize. On the other hand, in the presence of auto-regulation, we prove that cells in different layers can synchronize in a robust way and we give a characterization of the possible patterns of synchrony that can occur for auto-regulation feed-forward neural networks.

  20. Should we systematically test patients with clinically isolated syndrome for auto-antibodies?

    Science.gov (United States)

    Negrotto, Laura; Tur, Carmen; Tintoré, Mar; Arrambide, Georgina; Sastre-Garriga, Jaume; Río, Jordi; Comabella, Manuel; Nos, Carlos; Galán, Ingrid; Vidal-Jordana, Angela; Simon, Eva; Castilló, Joaquín; Palavra, Filipe; Mitjana, Raquel; Auger, Cristina; Rovira, Àlex; Montalban, Xavier

    2015-12-01

    Several autoimmune diseases (ADs) can mimic multiple sclerosis (MS). For this reason, testing for auto-antibodies (auto-Abs) is often included in the diagnostic work-up of patients with a clinically isolated syndrome (CIS). The purpose was to study how useful it was to systematically determine antinuclear-antibodies, anti-SSA and anti-SSB in a non-selected cohort of CIS patients, regarding the identification of other ADs that could represent an alternative diagnosis. From a prospective CIS cohort, we selected 772 patients in which auto-Ab levels were tested within the first year from CIS. Baseline characteristics of auto-Ab positive and negative patients were compared. A retrospective revision of clinical records was then performed in the auto-Ab positive patients to identify those who developed ADs during follow-up. One or more auto-Ab were present in 29.4% of patients. Only 1.8% of patients developed other ADs during a mean follow-up of 6.6 years. In none of these cases the concurrent AD was considered the cause of the CIS. In all cases the diagnosis of the AD resulted from the development of signs and/or symptoms suggestive of each disease. Antinuclear-antibodies, anti-SSA and anti-SSB should not be routinely determined in CIS patients but only in those presenting symptoms suggestive of other ADs. © The Author(s), 2015.

  1. Auto-validation of complete blood counts in an outpatient's regional laboratory.

    Science.gov (United States)

    Froom, Paul; Barak, Mira

    2015-02-01

    The rate of auto-validation is dependent on the ability of the laboratory information system (LIS) to integrate historical data, on the frequency and methods for identifying analyzer errors, and on the criteria for reflex testing, including the need for peripheral smear review. The rate of auto-validation in outpatient laboratories, however, is unclear. We examined 45,925 consecutive complete blood count (CBC) test results (1 January, 2014-31 January, 2014) from patients aged 50±24 years. The LIS auto-validates all samples according to set criteria. Technicians validated test results when previous CBC test results were required to determine: 1) the need for peripheral slide review and/or sample rerun or 2) the need for reflex testing to detect autoimmune hemolytic anemia or β-thalassemia minor. The auto-validation rates were 97.6% after rejecting results requiring validation to determine the need for a peripheral smear review and/or sample rerun. This decreased to 92.9% after including reflex testing to determine the reasons for normocytic and microcytic anemia. We estimated that auto-validation decreased the workload by 7.7-11.6 h per 3000 test results. We conclude that very high auto-validation rates are possible in outpatient general laboratories, leading to conformity in the validation process and a considerable estimated savings in technician time. Further studies are needed in other settings.

  2. Family factors associated with auto-aggressiveness in adolescents in Croatia.

    Science.gov (United States)

    Tripković, Mara; Francisković, Tanja; Grgić, Neda; Ercegović, Nela; Graovac, Mirjana; Zecević, Iva

    2013-12-01

    The aim of this research is to look into the roles of families' social situation and cohesion in adolescent auto-aggressiveness in Croatia. The research was conducted on a sample of Zagreb high school students which encompassed 701 pupils of both genders aged 14-19. The basic demographic data were obtained using the Structured Demographic and Family Data Questionnaire. Auto-aggressiveness was tested using a section of the Report on Youth Aged 11-18 and the Scale of Auto-destructiveness--SAD, whereas the family cohesion was tested with the Family Adaptability and Cohesion Evaluation Scales FACES III. The obtained results show differences according to the gender: girls are more prone to auto-aggressiveness than boys (t = -3.385, df = 565, p = 0.001) and girls more often show symptoms of destructiveness (t = -3.809, df = 637, p aggressiveness (t = 2.655, df = 653, p = 0.008). Significant family factors associated with auto-aggressiveness are parents' marital status (chi2 = 18.039, df = 4, p = 0.001), their financial situation (F(2.548) = 4.604, p = 0.010), alcoholic father (chi2 = 9.270, df = 2, p = 0.010), mentally ill mother (t = 5.264, df = 541, p aggressiveness. Family cohesion appears to be considerably associated with auto-aggressiveness and the adolescents that see their families as less cohesive have more mental problems (chi2 = 29.98, df = 2, p aggressiveness in adolescents.

  3. When should we perform a repeat training on adrenaline auto-injector use for physician trainees?

    Science.gov (United States)

    Topal, E; Bakirtas, A; Yilmaz, O; Karagol, I H E; Arga, M; Demirsoy, M S; Turktas, I

    2014-01-01

    Studies demonstrate that both doctors and patients may use adrenaline auto-injector improperly and the usage skills are improved by training. In this study, we aimed to determine the appropriate frequency of training to maintain skills for adrenaline auto-injector use. We invited all interns of 2011-2012 training period. At baseline, all participants were given theoretical and practical training on adrenaline auto-injector use. The participants were randomly assigned into two groups. We asked those in group 1 to demonstrate the use of adrenaline auto-injector trainer in the third month and those in group 2 in the sixth month. One hundred and sixty interns were enrolled. Compared with the beginning score, demonstration of skills at all the steps and total scores did not change for the group tested in the third month (p=0.265 and p=0.888, respectively). However; for the group examined in the sixth month; the demonstration of skills for proper use of the auto-injector at all steps and the mean time to administer adrenaline decreased (p=0.018 and padrenaline (p<0.001) and presumptive self-injection into thumb (p=0.029). Auto-injector usage skills of physician trainees decrease after the sixth month and are better in those who had skill reinforcement at 3 months, suggesting continued education and skill reinforcement may be useful. Copyright © 2013 SEICAP. Published by Elsevier Espana. All rights reserved.

  4. Intrinsic Tau Acetylation Is Coupled to Auto-Proteolytic Tau Fragmentation.

    Directory of Open Access Journals (Sweden)

    Todd J Cohen

    Full Text Available Tau proteins are abnormally aggregated in a range of neurodegenerative tauopathies including Alzheimer's disease (AD. Recently, tau has emerged as an extensively post-translationally modified protein, among which lysine acetylation is critical for normal tau function and its pathological aggregation. Here, we demonstrate that tau isoforms have different propensities to undergo lysine acetylation, with auto-acetylation occurring more prominently within the lysine-rich microtubule-binding repeats. Unexpectedly, we identified a unique intrinsic property of tau in which auto-acetylation induces proteolytic tau cleavage, thereby generating distinct N- and C-terminal tau fragments. Supporting a catalytic reaction-based mechanism, mapping and mutagenesis studies showed that tau cysteines, which are required for acetyl group transfer, are also essential for auto-proteolytic tau processing. Further mass spectrometry analysis identified the C-terminal 2nd and 4th microtubule binding repeats as potential sites of auto-cleavage. The identification of acetylation-mediated auto-proteolysis provides a new biochemical mechanism for tau self-regulation and warrants further investigation into whether auto-catalytic functions of tau are implicated in AD and other tauopathies.

  5. Cost Optimal Elastic Auto-Scaling in Cloud Infrastructure

    Science.gov (United States)

    Mukhopadhyay, S.; Sidhanta, S.; Ganguly, S.; Nemani, R. R.

    2014-12-01

    Today, elastic scaling is critical part of leveraging cloud. Elastic scaling refers to adding resources only when it is needed and deleting resources when not in use. Elastic scaling ensures compute/server resources are not over provisioned. Today, Amazon and Windows Azure are the only two platform provider that allow auto-scaling of cloud resources where servers are automatically added and deleted. However, these solution falls short of following key features: A) Requires explicit policy definition such server load and therefore lacks any predictive intelligence to make optimal decision; B) Does not decide on the right size of resource and thereby does not result in cost optimal resource pool. In a typical cloud deployment model, we consider two types of application scenario: A. Batch processing jobs → Hadoop/Big Data case B. Transactional applications → Any application that process continuous transactions (Requests/response) In reference of classical queuing model, we are trying to model a scenario where servers have a price and capacity (size) and system can add delete servers to maintain a certain queue length. Classical queueing models applies to scenario where number of servers are constant. So we cannot apply stationary system analysis in this case. We investigate the following questions 1. Can we define Job queue and use the metric to define such a queue to predict the resource requirement in a quasi-stationary way? Can we map that into an optimal sizing problem? 2. Do we need to get into a level of load (CPU/Data) on server level to characterize the size requirement? How do we learn that based on Job type?

  6. Flooded: An Auto-Ethnography of the 2011 Bangkok Flood

    Directory of Open Access Journals (Sweden)

    Erik Cohen

    2012-01-01

    Full Text Available In this personal account I report my perceptions, experiences, and conduct during the 2011 Bangkok flood, in which my home and neighbourhood have been badly inundated and damaged. Therefore, I draw on auto-ethnography as an increasingly popular, though controversial qualitative methodology in social sciences. Though personal, the account has some broader implications, deriving primarily from the examination of the relationship between my perceptions and conduct in the disaster and my life experiences and present social position, as set against the perceptions and conduct of my Thai wife, our neighbours, and the broader community. The contrast throws some light on an aspect of Thai culture rarely discussed in the literature: the Thai response to disaster. ----- In dieser persönlichen Darstellung berichte ich über meine Wahrnehmungen, Erfahrungen und mein Verhalten während der Überschwemmungen 2011 in Bangkok, in denen mein Heim und die Nachbarschaft überschwemmt und schwer beschädigt wurden. In diesem Zusammenhang stütze ich mich auf die Autoethnografie als zunehmend populäre, wenn auch umstrittene qualitative Methode in der sozialwissenschaftlichen Forschung. Trotz des persönlichen Zugangs einer Autoethnografie lässt diese breitere Schlussfolgerungen zu, die sich hauptsächlich aus der Betrachtung der Beziehung zwi- schen meinen Wahrnehmungen und Verhalten während der Katastrophe sowie meinen persönlichen Erfahrungen und meiner sozialen Stellung im Gegensatz zu den Wahrnehmungen und Verhalten meiner thailändischen Ehefrau, unserer Nachbarn und der Community ableiten lassen. Dieser Kontrast wirft Licht auf einen bisher in der Literatur wenig diskutierten Aspekt der thailändischen Kultur: der thailändischen Antwort auf Katastrophen.

  7. Study on optimized dispensing of F-18 FDG auto dispenser

    Energy Technology Data Exchange (ETDEWEB)

    Ji, Bong Geun; Lee, Sang Hun; Kim, Jong Eon; Kim, Won Tae; Kim, Tae Jeong [Dept. of Radiological Science, Kaya University, Kimhae (Korea, Republic of)

    2016-09-15

    This is a study on the optimized dispensing of the auto dispenser used for the purpose of reducing the exposure dose and accurate radiation dose of radioisotope with regard to the PET/CT practitioners. The research method was to find the optimized dispensing method through evaluating the results according to the syringe type, dispensing rate, and vial pressure and through the application of corrected values. As a result of this study, 9.38 mCi has been dispensed on average in the case of 5 ml syringe, and the reproducibility close to 10 mCi was shown at the dispense of 9.55 mCi in the case of 3 ml syringe. In the evaluation according to the dispensing rate, the quantity of radioisotope close to 10 mCi was dispensed at the rate of 5 mm/min when the measurement was carried out by increasing the rate by 5 mm/min units in the order of 5, 10, 15 and 20 mm/min . In the evaluation result according to the vial pressure before/after the use of Needle filter, it was measured to be 9.53 mCi before use and 9.84 mCi after use confirming that the dispensing after using Needle filter showed the optimal value. In addition, in the evaluation of radioactivity before/after the application of corrected values according to the increase in dispense frequency, it was measured 9.53 mCi before correction and 10.07 mCi after correction confirming that the value with correction applied was closer to the quantitative value. Thus, a good optimized method was confirmed to use a 3 ml syringe with dispensing rate of 5 mm/min, to use a Needle filter at dispensing, and to set the corrected value of [y = 0.097 × χ] according to the dispensing frequency of equipment.

  8. Intermediate species measurement during iso-butanol auto-ignition

    KAUST Repository

    Ji, Weiqi

    2015-10-01

    © 2015 The Combustion Institute.Published by Elsevier Inc. All rights reserved. This work presents the time histories of intermediate species during the auto-ignition of iso-butanol at high pressure and intermediate temperature conditions obtained using a rapid compression machine and recently developed fast sampling system. Iso-butanol ignition delays were acquired for iso-butanol/O2 mixture with an inert/O2 ratio of 7.26, equivalence ratio of 0.4, in the temperature range of 840-950 K and at pressure of 25 bar. Fast sampling and gas chromatography were used to acquire and quantify the intermediate species during the ignition delay of the same mixture at P = 25.3 bar and T = 905 K. The ignition delay times and quantitative measurements of the mole fraction time histories of methane, ethene, propene, iso-butene, iso-butyraldehyde, iso-butanol, and carbon monoxide were compared with predictions from the detailed mechanisms developed by Sarathy et al., Merchant et al., and Cai et al. It is shown that while the Sarathy mechanism well predicts the overall ignition delay time, it overpredicts ethene by a factor of 6-10, underpredicts iso-butene by a factor of 2, and overpredicts iso-butyraldehyde by a factor of 2. Reaction path and sensitivity analyses were carried out to identify the reactions responsible for the observed inadequacy. The rates of iso-butanol hydrogen atom abstraction by OH radical and the beta-scission reactions of hydroxybutyl radicals were updated based on recently published quantum calculation results. Significant improvements were achieved in predicting ignition delay at high pressures (25 and 30 bar) and the species concentrations of ethene and iso-butene. However, the updated mechanism still overpredicts iso-butyraldehyde concentrations. Also, the updated mechanism degrades the prediction in ignition delay at lower pressure (15 bar) compared to the original mechanism developed by Sarathy et al.

  9. Auto-correcting for atmospherical effects in thermal hyperspectral measurements

    Science.gov (United States)

    Timmermans, Joris; Buitrago-Acevedo, Maria; Verhoef, Wout

    2017-04-01

    Correct estimation of soil and vegetation thermal emissivity's has been of huge importance in remote sensing studies. Field measurements of the leaf/soil and canopy emissivity can lead to estimations of water content. Consequently several studies have been performed with the objective of identifying the spectral behavior of the emissivity. However such measurements provide additional challenges before any retrieval can successfully be performed. While in laboratory the influence of the atmospheric conditions can be controlled in field experiments this cannot be done. In most cases such atmospheric correction however requires detailed knowledge of the atmospheric constituents at the time of the measurements. The objective of this research was to create an auto-atmospherically correct thermal hyperspectral emissivity measurements for retrieving canopy water content. For this hyperspectral thermal measurements were obtained during ESAs REFLEX campaign in 2012 using a MIDAC FTIR radiometer. MODTRAN simulations were used to construct a simple quadratic radiative transfer model that couples atmospheric transmissivities to the different gas constituents. This model was afterwards used to estimate the concentrations of H20 (g) and CO2 (g). The radiative measurements were afterwards corrected for these gas absorptions. Finally a temperature emissivity separation was applied to estimate the emissivities of the different land surface components. Gas concentrations were validated against measurements of a LICOR 7500 taken in parallel to the MIDAC measurements. It is observed that in general the relative errors are around 25% of the LICOR measurements, which are in the same range as the instrumental errors of the eddy-covariance system (15-30%). The correction of the absorption features proved however more difficult and resulted in overestimations of the correction-terms; 1) because spectral collocation of the simulations with the observations proved troublesome, and 2 because

  10. Fermi-Pasta-Ulam auto recurrence in the description of the electrical activity of the heart.

    Science.gov (United States)

    Novopashin, M A; Shmid, A V; Berezin, A A

    2017-04-01

    The authors proposed and mathematically described model of a new type of the Fermi-Pasta-Ulam recurrence (the FPU auto recurrence) and hypothesized an adequate description of the heart's electrical dynamics within the observed phenomenon. The dynamics of the FPU auto recurrence making appropriate electrical dynamics of the normal functioning of the heart in the form of an electrocardiogram (ECG) was obtained by a computer model study. The model solutions in the form of the FPU auto recurrence - ECG Fourier spectrum were evaluated for resistance to external disturbances in the form of random effects, as well as periodic perturbation at a frequency close to the heart beating rate of about 1Hz. In addition, in order to simulate the dynamics of myocardial infarction model, studied the effect of the surface area of the myocardium on the stability and shape of the auto recurrence - ECG spectrum. It has been found that the intense external disturbing periodic impacts at a frequency of about 1Hz lead to a sharp disturbance spectrum shape FPU auto recurrence - ECG structure. In addition, the decrease in the surface of the myocardium by 50% in the model led to the destruction of structures of the auto recurrence - ECG, which corresponds to the state of atrial myocardium. Research models have revealed a hypothetical basis of coronary heart disease in the form of increasing the energy of high-frequency harmonics spectrum of the auto recurrence by reducing the energy of low-frequency harmonic spectrum of the auto recurrence, which ultimately leads to a sharp decrease in myocardial contractility. In order to test the hypothesis has been studied more than 20,000 ECGs both healthy people and patients with cardiovascular disease. As a result of these studies, it was found that the dynamics of the electrical activity of normal functioning of the heart can be interpreted by the display of the detected by authors the FPU auto recurrence, and coronary heart disease is a violation of

  11. Proliferation of epithelial rests of Malassez following auto-transplantation of third molars: a case report

    Directory of Open Access Journals (Sweden)

    Schepers Serge

    2010-10-01

    Full Text Available Abstract Introduction Auto-transplantation of third molars is frequently undertaken in order to restore a perfect occlusion and to improve mastication following a substantial loss of molars. However, little is known about the precise role of the periodontal membrane during this procedure. Therefore, we investigated if the epithelial rests of Malassez persist in the periodontal ligament of auto-transplanted teeth and, if so, whether these may show signs of a neuro-epithelial relationship. Case presentation We report a case of a 21-year-old Caucasian woman who underwent an auto-transplantation of two third molars. After two years, renewed progressive caries of the auto-transplanted teeth led to the removal of the auto-transplanted elements. The periodontal ligament was removed and studied with a light and transmission electron microscope. Conclusion In this report we examined the ultrastructure of the periodontal ligament after auto-transplantation in order to see if the periodontal ligament recovers completely from this intervention. We observed fully developed blood vessels and a re-innervation of the epithelial rests of Malassez which were proliferating following auto-transplantation. This proliferation might be critical in the remodelling of the alveolar socket in order to provide a perfect fit for the transplanted tooth. In order to minimalise the damage to the epithelial rests of Malassez, the extraction of the tooth should be as atraumatic as possible in order to provide an optimal conservation of the periodontal ligament which will be beneficial to the healing-process.

  12. Tuba-ovarian auto-amputation caused by ovarian teratoma in an adolescent girl.

    Science.gov (United States)

    Atıcı, Ahmet; Yılmaz, Engin; Karaman, Ayşe; Apaydın, Sema; Afşarlar, Çağatay Evrim

    2017-01-01

    Atıcı A, Yılmaz E, Karaman A, Apaydın S, Afşarlar ÇE. Tuba-ovarian auto-amputation caused by ovarian teratoma in an adolescent girl. Turk J Pediatr 2017; 59: 90-92. Ovarian auto-amputation is an extremely rare condition commonly encountered in the perinatal period. Spontaneous or secondary torsion of the ovary caused by an ovarian lesion may result in infarction and subsequent auto-amputation of the ovary. This paper demonstrates a case that underwent laparoscopic appendectomy with an incidental calcified auto-amputated right ovary. A 16-year-old adolescent girl was admitted to our department with a history of one-day abdominal pain. Physical examination of the patient revealed abdominal tenderness and rigidity on right lower quadrant. Her white blood cell count was 11x103/mL, and C-reactive protein was 69 mg/L. The patient underwent a laparoscopic appendectomy with a provisional diagnosis of acute appendicitis, and further exploration revealed a 2x2 cm white ovoid mass floating freely in the pelvis. The left ovary was clearly identified in its usual localization, but the right tuba was blindly ending without any fimbria or ovary. Postoperative course of the patient was uneventful, and she was discharged on postoperative day 2. The histopathological examination revealed a necrotic calcified ovarian teratoma. Auto-amputated ovary is a rare occasion mostly encountered during perinatal period, and it may be unilateral or bilateral. An auto-amputated ovarian mass may rarely be a teratoma although the most common cause of auto-amputation during perinatal and adolescent period is ovarian torsion due to an ovarian cyst.

  13. Auto-percepções, auto-estima, ansiedade físico-social e imagem corporal – estudo comparativo entre instrutores de fitness e praticantes de actividade física

    Directory of Open Access Journals (Sweden)

    João Filipe Santos

    2007-06-01

    Full Text Available O instrutor de fitness é constantemente confrontado, nas suas aulas, com a sua imagem corporal, auto-conceito, auto-estima e com a apreciação da mesma pelo próprio e pela classe. Assim, o modo como o instrutor se auto-percepciona e como este pensa como os outros o percepcionam tem vindo a ser um tema ainda por responder. O propósito de examinar o modo como o Autoconceito, a Auto-estima e a Imagem Corporal se reflecte na vida profissional do instrutor de fitness poderá, de alguma forma, cooperar na procura dessa resposta.

  14. The continental integration of the North American automobile industry: from the Auto Pact to the FTA and beyond

    OpenAIRE

    Holmes, J

    1992-01-01

    The continental integration of the US and Canadian automobile industries quickly followed the negotiation of a sectorial managed trade agreement -- the Auto Pact -- in 1965. Thus the recent Canada - US Free Trade Agreement (FTA) will likely have less short-term impact on restructuring in the auto industry than it will in most other industries. The paper begins with an analysis of the significant restructuring that occurred within the North American auto industry during the 1980s in response t...

  15. A kinetic model of TBP auto-regulation exhibits bistability.

    Science.gov (United States)

    Gokhale, Sucheta A; Roshan, Reema; Khetan, Vivek; Pillai, Beena; Gadgil, Chetan J

    2010-08-05

    TATA Binding Protein (TBP) is required for transcription initiation by all three eukaryotic RNA polymerases. It participates in transcriptional initiation at the majority of eukaryotic gene promoters, either by direct association to the TATA box upstream of the transcription start site or by indirectly localizing to the promoter through other proteins. TBP exists in solution in a dimeric form but binds to DNA as a monomer. Here, we present the first mathematical model for auto-catalytic TBP expression and use it to study the role of dimerization in maintaining the steady state TBP level. We show that the autogenous regulation of TBP results in a system that is capable of exhibiting three steady states: an unstable low TBP state, one stable state corresponding to a physiological TBP concentration, and another stable steady state corresponding to unviable cells where no TBP is expressed. Our model predicts that a basal level of TBP is required to establish the transcription of the TBP gene, and hence for cell viability. It also predicts that, for the condition corresponding to a typical mammalian cell, the high-TBP state and cell viability is sensitive to variation in DNA binding strength. We use the model to explore the effect of the dimer in buffering the response to changes in TBP levels, and show that for some physiological conditions the dimer is not important in buffering against perturbations. Results on the necessity of a minimum basal TBP level support the in vivo observations that TBP is maternally inherited, providing the small amount of TBP required to establish its ubiquitous expression. The model shows that the system is sensitive to variations in parameters indicating that it is vulnerable to mutations in TBP. A reduction in TBP-DNA binding constant can lead the system to a regime where the unviable state is the only steady state. Contrary to the current hypotheses, we show that under some physiological conditions the dimer is not very important in

  16. Comparison of two nicotine dependence measures for use with Korean American Women: The FTND and AUTOS

    Directory of Open Access Journals (Sweden)

    Sun S. Kim

    2017-06-01

    Full Text Available This study compares psychometric properties of the Fagerström Test for Nicotine Dependence (FTND and Autonomy over Tobacco Scale (AUTOS, which are measures of nicotine dependence. This study is a secondary analysis of data obtained from a smoking cessation study conducted with 49 Korean American women. We compared the FTND and AUTOS assessed at baseline regarding their internal consistency reliability and concurrent and predictive validities. The AUTOS outperformed the FTND in reliability and concurrent validity by yielding a higher Cronbach’s alpha and having significant relationships with smoking-related variables such as age at smoking onset, perceived risks of quitting, and self-efficacy in quitting. In contrast, there was no relationship between the FTND and any of the variables. Both measures had a significant relationship with post-quit nicotine withdrawal symptoms but failed to predict abstinence at follow-ups. The AUTOS seems to be a better assessment tool for Korean American women than the FTND. Before fully adopting the AUTOS as a measure of nicotine dependence for this group, factor structure of the scale should be tested with a larger sample of Korean American women.

  17. Epinephrine auto-injector needle length: what is the ideal length?

    Science.gov (United States)

    Song, T Ted; Lieberman, Phil

    2016-08-01

    The purpose of this manuscript is to review the literature on the clinical effects of the needle length of epinephrine (adrenaline) auto-injectors. Epinephrine has maximal pharmacodynamic effect within 10 min of intramuscular administration into the thigh. Prefilled epinephrine auto-injectors are designed for simplicity of use and safety. Auto-injectors are primarily used by patients in an unsupervised setting in cases of anaphylaxis. There are weight-appropriate doses of epinephrine available with auto-injectors that are prefilled, to prevent dosing errors, with 0.15, 0.30, and 0.50 mg amounts. In addition, needle lengths vary from 1.17 to 2.50 cm. The recommended needle lengths differ between adults and pediatric patients. In addition, the needle lengths differ between devices as well. There are concerns that the needle length may be too short in select obese patients. Yet, there are also concerns that the needle length may be too long in some patients. Factors that affect the depth of the injection, and therefore the pharmacokinetics of the drug, include not only the needle length but also the BMI, obesity, compression of soft tissue, and propulsion. Epinephrine auto-injectors have different needle lengths. Using the right device with appropriate needle length based on BMI, obesity, and employing the proper technique can improve the outcome in an anaphylactic event.

  18. Ventilator auto-cycling from cardiogenic oscillations: case report and review of literature.

    Science.gov (United States)

    Noujeim, Carlos; Bouakl, Imad; El-Khatib, Mohamad; Bou-Khalil, Pierre

    2013-09-01

    Brain death is the total loss of all brain and brain stem functions, and its diagnosis is often confirmed by an apnoea test, which relies on disconnecting the patient from the ventilator. Auto-triggering or auto-cycling is defined as a ventilator being triggered in the absence of patient effort, intrinsic respiratory drive or inspiratory muscle activity. Ventilator auto-triggering could delay the diagnosis of brain death leading to unnecessary admission for the patient and false hopes of recovery for the family. We report a case of ventilator auto-triggering associated with cardiogenic oscillations in a female patient. We confirmed the finding of ventilator auto-triggering by changing the patient's position and reassessing the triggering thresholds. Brain death was then confirmed by apnoea test. This case is presented to arouse the awareness of the medical staff and nurses to this phenomenon, which can mimic an intrinsic respiratory effort in patients allegedly diagnosed with brain death. Along with this case report, we review the English language publications for similar cases. © 2013 British Association of Critical Care Nurses.

  19. A Real-Time Non-invasive Auto-bioluminescent Urinary Bladder Cancer Xenograft Model.

    Science.gov (United States)

    John, Bincy Anu; Xu, Tingting; Ripp, Steven; Wang, Hwa-Chain Robert

    2017-02-01

    The study was to develop an auto-bioluminescent urinary bladder cancer (UBC) xenograft animal model for pre-clinical research. The study used a humanized, bacteria-originated lux reporter system consisting of six (luxCDABEfrp) genes to express components required for producing bioluminescent signals in human UBC J82, J82-Ras, and SW780 cells without exogenous substrates. Immune-deficient nude mice were inoculated with Lux-expressing UBC cells to develop auto-bioluminescent xenograft tumors that were monitored by imaging and physical examination. Lux-expressing auto-bioluminescent J82-Lux, J82-Ras-Lux, and SW780-Lux cell lines were established. Xenograft tumors derived from tumorigenic Lux-expressing auto-bioluminescent J82-Ras-Lux cells allowed a serial, non-invasive, real-time monitoring by imaging of tumor development prior to the presence of palpable tumors in animals. Using Lux-expressing auto-bioluminescent tumorigenic cells enabled us to monitor the entire course of xenograft tumor development through tumor cell implantation, adaptation, and growth to visible/palpable tumors in animals.

  20. Violência escolar e auto-estima de adolescentes Violence at school and teenager's self-esteem

    Directory of Open Access Journals (Sweden)

    Lucimar Câmara Marriel

    2006-04-01

    Full Text Available Este artigo procura estudar a associação entre auto-estima e violências que ocorrem no ambiente escolar. Apresenta resultados obtidos em pesquisa realizada em escolas públicas e particulares de São Gonçalo, Estado do Rio de Janeiro. Emprega basicamente metodologia quantitativa (inquérito epidemiológico com uma amostra de 1.686 alunos com alunos das 7ª e 8ª séries do ensino fundamental e 1º e 2º anos do ensino médio. Os resultados indicam que alunos com baixa auto-estima relacionam-se de forma pior com colegas e professores que os pares de elevada auto-estima, além de se colocarem mais freqüentemente na posição de vítimas de violência na escola e terem mais dificuldade de se sentir bem no espaço escolar. São apontados alguns programas nacionais que têm tentado abordar o problema da violência na escola.The purpose of this article is to study the relationship between self-esteem and the acts of physical and psychological violence that arise in school. It provides results a research carried out both in public and private schools in São Gonçalo, Rio de Janeiro State. An epidemiological survey with a sample of 1,686 students was used with 7th and 8th grade elementary and 1st and 2nd grade secondary school students. As pointed out by the results, for those students with a low self-esteem it seems to be more difficult to get along both with classmates and teachers than for those with a high self-esteem. Not to mention that more often than the others the former pose as victims of violence at school and find it more difficult to feel at home there. This paper addresses some Brazilian programs which have been attempting to approach the issue of violence at school.

  1. Arabidopsis TNL-WRKY domain receptor RRS1 contributes to temperature-conditioned RPS4 auto-immunity

    Directory of Open Access Journals (Sweden)

    Katharina eHeidrich

    2013-10-01

    Full Text Available In plant effector-triggered immunity (ETI, intracellular nucleotide binding-leucine rich repeat (NLR receptors are activated by specific pathogen effectors. The Arabidopsis TIR (Toll Interleukin1 receptor domain-NLR (denoted TNL gene pair, RPS4 and RRS1, confers resistance to Pseudomonas syringae pv tomato (Pst strain DC3000 expressing the Type III-secreted effector, AvrRps4. Nuclear accumulation of AvrRps4, RPS4 and the TNL resistance regulator EDS1 is necessary for ETI. RRS1 possesses a C-terminal ‘WRKY’ transcription factor DNA binding domain suggesting that important RPS4/RRS1 recognition and/or resistance signaling events occur at the nuclear chromatin. In Arabidopsis accession Ws-0, the RPS4Ws/RRS1Ws allelic pair governs resistance to Pst/AvrRps4 accompanied by host programmed cell death (pcd. In accession Col-0, RPS4Col/RRS1Col effectively limits Pst/AvrRps4 growth without pcd. Constitutive expression of HA-StrepII tagged RPS4Col (in a 35S:RPS4-HS line confers temperature conditioned EDS1-dependent auto-immunity. Here we show that a high (28oC, non-permissive to moderate (19oC, permissive temperature shift of 35S:RPS4-HS plants can be used to follow defense-related transcriptional dynamics without a pathogen effector trigger. By comparing responses of 35S:RPS4-HS with 35S:RPS4-HS rrs1-11 and 35S:RPS4-HS eds1-2 mutants, we establish that RPS4Col auto-immunity depends entirely on EDS1 and partially on RRS1Col. Examination of gene expression microarray data over 24h after temperature shift reveals a mainly quantitative RRS1Col contribution to up- or down-regulation of a small subset of RPS4Col-reprogrammed, EDS1-dependent genes. We find significant over-representation of WRKY transcription factor binding W-box cis-elements within the promoters of these genes. Our data show that RRS1Col contributes to temperature-conditioned RPS4Col auto-immunity and are consistent with activated RPS4Col engaging RRS1Col for resistance signaling.

  2. Surveillance of the use of adrenaline auto-injectors in Japanese children.

    Science.gov (United States)

    Ito, Komei; Ono, Manabu; Kando, Naoyuki; Matsui, Teruaki; Nakagawa, Tomoko; Sugiura, Shiro; Ebisawa, Motohiro

    2017-08-04

    The appropriate usage of an adrenaline auto-injector (AAI, Epipen®) is a key aspect of patient and social education in the management of anaphylaxis. However, although AAIs are being prescribed increasingly frequently, there are few reports on their actual use. The Anaphylaxis Working Group of the Japanese Society of Pediatric Allergy and Clinical Immunology requested that society members register cases in which AAIs were used. Two hundred and sixty-six cases were collected from March 2014 to March 2016. The cases included 240 events of immediate-type food allergies caused by cow's milk (n = 100), hen's egg (n = 42), wheat (n = 40), and peanuts (n = 11). Exercise-related events were reported in 19 cases; however, the diagnosis of food-dependent exercise-induced anaphylaxis with a specific causative food was only made in 4 cases (wheat, n = 2; fish, n = 1; squid, n = 1). The frequent reasons for the causative intake included programmed intake (n = 48), failure to check the food labeling (n = 43), and consuming an inappropriate food (n = 26). AAIs were used at schools or nurseries in 67 cases, with school or nursery staff members administering the AAI in 39 cases (58%). On arriving at the hospital, the symptom grade was improved in 71% of the cases, while grade 4 symptoms remained in 20% of the cases. No lethal cases or sequelae were reported. AAIs were used effectively, even by school teachers. The need to visit a hospital after the use of an AAI should be emphasized because additional treatment might be required. Copyright © 2017 Japanese Society of Allergology. Production and hosting by Elsevier B.V. All rights reserved.

  3. Software Design of Mobile Antenna for Auto Satellite Tracking Using Modem Correction and Elevation Azimuth Method

    Directory of Open Access Journals (Sweden)

    Djamhari Sirat

    2010-10-01

    Full Text Available Pointing accuracy is an important thing in satellite communication. Because the satellite’s distance to the surface of the earth's satellite is so huge, thus 1 degree of pointing error will make the antenna can not send data to satellites. To overcome this, the auto-tracking satellite controller is made. This system uses a microcontroller as the controller, with the GPS as the indicator location of the antenna, digital compass as the beginning of antenna pointing direction, rotary encoder as sensor azimuth and elevation, and modem to see Eb/No signal. The microcontroller use serial communication to read the input. Thus the programming should be focused on in the UART and serial communication software UART. This controller use 2 phase in the process of tracking satellites. Early stages is the method Elevation-Azimuth, where at this stage with input from GPS, Digital Compass, and the position of satellites (both coordinates, and height that are stored in microcontroller. Controller will calculate the elevation and azimuth angle, then move the antenna according to the antenna azimuth and elevation angle. Next stages is correction modem, where in this stage controller only use modem as the input, and antenna movement is set up to obtain the largest value of Eb/No signal. From the results of the controller operation, there is a change in the value of the original input level from -81.7 dB to -30.2 dB with end of Eb/No value, reaching 5.7 dB.

  4. FRACOR-software toolbox for deterministic mapping of fracture corridors in oil fields on AutoCAD platform

    Science.gov (United States)

    Ozkaya, Sait I.

    2018-03-01

    Fracture corridors are interconnected large fractures in a narrow sub vertical tabular array, which usually traverse entire reservoir vertically and extended for several hundreds of meters laterally. Fracture corridors with their huge conductivities constitute an important element of many fractured reservoirs. Unlike small diffuse fractures, actual fracture corridors must be mapped deterministically for simulation or field development purposes. Fracture corridors can be identified and quantified definitely with borehole image logs and well testing. However, there are rarely sufficient image logs or well tests, and it is necessary to utilize various fracture corridor indicators with varying degrees of reliability. Integration of data from many different sources, in turn, requires a platform with powerful editing and layering capability. Available commercial reservoir characterization software packages, with layering and editing capabilities, can be cost intensive. CAD packages are far more affordable and may easily acquire the versatility and power of commercial software packages with addition of a small software toolbox. The objective of this communication is to present FRACOR, a software toolbox which enables deterministic 2D fracture corridor mapping and modeling on AutoCAD platform. The FRACOR toolbox is written in AutoLISPand contains several independent routines to import and integrate available fracture corridor data from an oil field, and export results as text files. The resulting fracture corridor maps consists mainly of fracture corridors with different confidence levels from combination of static and dynamic data and exclusion zones where no fracture corridor can exist. The exported text file of fracture corridors from FRACOR can be imported into an upscaling programs to generate fracture grid for dual porosity simulation or used for field development and well planning.

  5. Optimisation sous contraintes par intelligence collective auto-adaptative

    OpenAIRE

    Khichane, Madjid

    2010-01-01

    In this thesis, we focused on the implementation of self-adaptive algorithms for solving optimization problems modeled in a Constraint Programming (CP) language. We focus on to the Ant Colony Optimization (ACO) algorithms. We have developed three contributions, namely: (1) Integration of ACO algorithms in a constraint programming language for solving constraint satisfaction problems, (2) Proposal of a generic hybrid algorithm which combines ACO and CP approach to solving combinatorial optimiz...

  6. DOVIS 2.0: an efficient and easy to use parallel virtual screening tool based on AutoDock 4.0

    Directory of Open Access Journals (Sweden)

    Wallqvist Anders

    2008-09-01

    Full Text Available Abstract Background Small-molecule docking is an important tool in studying receptor-ligand interactions and in identifying potential drug candidates. Previously, we developed a software tool (DOVIS to perform large-scale virtual screening of small molecules in parallel on Linux clusters, using AutoDock 3.05 as the docking engine. DOVIS enables the seamless screening of millions of compounds on high-performance computing platforms. In this paper, we report significant advances in the software implementation of DOVIS 2.0, including enhanced screening capability, improved file system efficiency, and extended usability. Implementation To keep DOVIS up-to-date, we upgraded the software's docking engine to the more accurate AutoDock 4.0 code. We developed a new parallelization scheme to improve runtime efficiency and modified the AutoDock code to reduce excessive file operations during large-scale virtual screening jobs. We also implemented an algorithm to output docked ligands in an industry standard format, sd-file format, which can be easily interfaced with other modeling programs. Finally, we constructed a wrapper-script interface to enable automatic rescoring of docked ligands by arbitrarily selected third-party scoring programs. Conclusion The significance of the new DOVIS 2.0 software compared with the previous version lies in its improved performance and usability. The new version makes the computation highly efficient by automating load balancing, significantly reducing excessive file operations by more than 95%, providing outputs that conform to industry standard sd-file format, and providing a general wrapper-script interface for rescoring of docked ligands. The new DOVIS 2.0 package is freely available to the public under the GNU General Public License.

  7. DOVIS 2.0: an efficient and easy to use parallel virtual screening tool based on AutoDock 4.0.

    Science.gov (United States)

    Jiang, Xiaohui; Kumar, Kamal; Hu, Xin; Wallqvist, Anders; Reifman, Jaques

    2008-09-08

    Small-molecule docking is an important tool in studying receptor-ligand interactions and in identifying potential drug candidates. Previously, we developed a software tool (DOVIS) to perform large-scale virtual screening of small molecules in parallel on Linux clusters, using AutoDock 3.05 as the docking engine. DOVIS enables the seamless screening of millions of compounds on high-performance computing platforms. In this paper, we report significant advances in the software implementation of DOVIS 2.0, including enhanced screening capability, improved file system efficiency, and extended usability. To keep DOVIS up-to-date, we upgraded the software's docking engine to the more accurate AutoDock 4.0 code. We developed a new parallelization scheme to improve runtime efficiency and modified the AutoDock code to reduce excessive file operations during large-scale virtual screening jobs. We also implemented an algorithm to output docked ligands in an industry standard format, sd-file format, which can be easily interfaced with other modeling programs. Finally, we constructed a wrapper-script interface to enable automatic rescoring of docked ligands by arbitrarily selected third-party scoring programs. The significance of the new DOVIS 2.0 software compared with the previous version lies in its improved performance and usability. The new version makes the computation highly efficient by automating load balancing, significantly reducing excessive file operations by more than 95%, providing outputs that conform to industry standard sd-file format, and providing a general wrapper-script interface for rescoring of docked ligands. The new DOVIS 2.0 package is freely available to the public under the GNU General Public License.

  8. Fault tolerant control of multivariable processes using auto-tuning PID controller.

    Science.gov (United States)

    Yu, Ding-Li; Chang, T K; Yu, Ding-Wen

    2005-02-01

    Fault tolerant control of dynamic processes is investigated in this paper using an auto-tuning PID controller. A fault tolerant control scheme is proposed composing an auto-tuning PID controller based on an adaptive neural network model. The model is trained online using the extended Kalman filter (EKF) algorithm to learn system post-fault dynamics. Based on this model, the PID controller adjusts its parameters to compensate the effects of the faults, so that the control performance is recovered from degradation. The auto-tuning algorithm for the PID controller is derived with the Lyapunov method and therefore, the model predicted tracking error is guaranteed to converge asymptotically. The method is applied to a simulated two-input two-output continuous stirred tank reactor (CSTR) with various faults, which demonstrate the applicability of the developed scheme to industrial processes.

  9. Competitive strategies of late followers in auto industry: Case study Hyundai-Kia

    Directory of Open Access Journals (Sweden)

    Rakita Branko

    2017-01-01

    Full Text Available This paper analyzes competitive strategy of late followers in auto industry in the case of Hyundai Kia Auto Group (HKAG. The global economic crisis has had a strong impact on the leaders in auto industry. HKAG took advantage of the crisis and increased sales and global market share at the expense of the leaders in the industry. We found that during the crisis the company achieved excellent results thanks to innovative marketing and sales strategies combined with top quality, product design and productivity. Growing competition and changes in business environment in the post-crisis period jeopardized the future growth of the company. The company reacted to the changes in business environment by shifting the focus to the luxury segment and green vehicles, by launching independent luxury brand Genesis and by scaling up investment in R&D.

  10. Development of Auto-tuning System for the Process Optimal Control of Wolsung NPP

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, M.H.; Park, I.S.; Shin, C.H. [Korea Electric Power Research Institute, Taejeon (Korea, Republic of)

    1997-12-31

    This was written as the research final report of {sup D}evelopment of Auto-tuning System for the Process Optimal Control of Wolsung NPP{sup (}95ZS13). In this research, a new PID controller auto-tuning algorithm and Auto-tuning System which can simulate and analyze control system performance have been developed for process optimal control of Wolsung NPP. The developed algorithm can estimate a process model without using test signal generation and calculate the optimal PID control parameters which can satisfy desired control performances. The system can be used in the PID controller tuning or retuning of operating plants or initial startup plants as well as fossil plants. (author). 40 refs., 117 figs., 33 tabs.

  11. Auto-trilevel versus bilevel positive airway pressure ventilation for hypercapnic overlap syndrome patients.

    Science.gov (United States)

    Su, Mei; Huai, De; Cao, Juan; Ning, Ding; Xue, Rong; Xu, Meijie; Huang, Mao; Zhang, Xilong

    2017-06-13

    Although bilevel positive airway pressure (Bilevel PAP) therapy is usually used for overlap syndrome (OS), there is still a portion of OS patients in whom Bilevel PAP therapy could not simultaneously eliminate residual apnea events and hypercapnia. The current study was expected to explore whether auto-trilevel positive airway pressure (auto-trilevel PAP) therapy with auto-adjusting end expiratory positive airway pressure (EEPAP) can serve as a better alternative for these patients. From January of 2014 to June of 2016, 32 hypercapnic OS patients with stable chronic obstructive pulmonary diseases (COPD) and moderate-to-severe obstructive sleep apnea syndrome (OSAS) were recruited. Three variable modes of positive airway pressure (PAP) from the ventilator (Prisma25ST, Weinmann Inc., Germany) were applicated for 8 h per night. We performed the design of each mode at each night with an interval of two nights with no PAP treatment as a washout period among different modes. In Bilevel-1 mode (Bilevel-1), the expiratory positive airway pressure (EPAP) delivered from Bilevel PAP was always set as the lowest PAP for abolishment of snoring. For each patient, the inspiratory positive airway pressure (IPAP) was constantly set the same as the minimal pressure for keeping end-tidal CO2 (ETCO2) ≤45 mmHg for all three modes. However, the EPAP issued by Bilevel PAP in Bilevel-2 mode (Bilevel-2) was kept 3 cmH2O higher than that in Bilevel-1. In auto-trilevel mode (auto-trilevel) with auto-trilevel PAP, the initial part of EPAP was fixed at the same PAP as that in Bilevel-1 while the EEPAP was automatically regulated to rise at a range of ≤4 cmH2O based on nasal airflow wave changes. Comparisons were made for parameters before and during or following treatment as well as among different PAP therapy modes. The following parameters were compared such as nocturnal apnea hypopnea index (AHI), minimal SpO2 (minSpO2), arousal index, sleep structure and efficiency, morning PaCO2

  12. [DNA extraction from bones and teeth using AutoMate Express forensic DNA extraction system].

    Science.gov (United States)

    Gao, Lin-Lin; Xu, Nian-Lai; Xie, Wei; Ding, Shao-Cheng; Wang, Dong-Jing; Ma, Li-Qin; Li, You-Ying

    2013-04-01

    To explore a new method in order to extract DNA from bones and teeth automatically. Samples of 33 bones and 15 teeth were acquired by freeze-mill method and manual method, respectively. DNA materials were extracted and quantified from the triturated samples by AutoMate Express forensic DNA extraction system. DNA extraction from bones and teeth were completed in 3 hours using the AutoMate Express forensic DNA extraction system. There was no statistical difference between the two methods in the DNA concentration of bones. Both bones and teeth got the good STR typing by freeze-mill method, and the DNA concentration of teeth was higher than those by manual method. AutoMate Express forensic DNA extraction system is a new method to extract DNA from bones and teeth, which can be applied in forensic practice.

  13. Design of an adaptive backstepping controller for auto-berthing a cruise ship under wind loads

    Directory of Open Access Journals (Sweden)

    Park Jong-Yong

    2014-06-01

    Full Text Available The auto-berthing of a ship requires excellent control for safe accomplishment. Crabbing, which is the pure sway motion of a ship without surge velocity, can be used for this purpose. Crabbing is induced by a peculiar operation procedure known as the push-pull mode. When a ship is in the push-pull mode, an interacting force is induced by complex turbulent flow around the ship generated by the propellers and side thrusters. In this paper, three degrees of freedom equations of the motions of crabbing are derived. The equations are used to apply the adaptive backstepping control method to the auto-berthing controller of a cruise ship. The controller is capable of handling the system nonlinearity and uncertainty of the berthing process. A control allocation algorithm for a ship equipped with two propellers and two side thrusters is also developed, the performance of which is validated by simulation of auto-berthing.

  14. Application of the AutoClass Automatic Bayesian Classification System to HMI Solar Images

    Science.gov (United States)

    Parker, D. G.; Beck, J. G.; Ulrich, R. K.

    2011-12-01

    When applied to a sample set of observed data, the Bayesian automatic classification system known as AutoClass finds a set of class definitions based on specified attributes of the data, such as magnetic field and intensity, without human supervision. These class definitions can then be applied to new data sets to identify automatically in them the classes found in the sample set. AutoClass can be applied to solar magnetic and intensity images to identify surface features associated with different values of magnetic and intensity fields in a consistent manner without the need for human judgment. AutoClass has been applied to Mt. Wilson magnetograms and intensity-grams to identify solar surface features associated with variations in total solar irradiance (TSI) and, using those identifications, to improve modeling of TSI variations over time. (Ulrich, et al, 2010) Here, we apply AutoClass to observables derived from the high resolution 4096 x 4096 HMI magnetic, intensity continuum, line width and line depth images to identify solar surface regions which may be associated with variations in TSI and other solar irradiance measurements. To prevent small instrument artifacts from interfering with class identification, we apply a flat-field correction and a rotationally shifted temporal average to the HMI images prior to processing with AutoClass. This pre-processing also allows an investigation of the sensitivity of AutoClass to instrumental artifacts. The ability to categorize automatically surface features in the HMI images holds out the promise of consistent, relatively quick and manageable analysis of the large quantity of data available in these highly resolved images and the use of that analysis to enhance understanding of the physical processes at work in solar surface features and their implications for the solar-terrestrial environment. Reference Ulrich, R.K., Parker, D, Bertello, L. and Boyden, J. 2010, Solar Phys., 261, 11.

  15. Skin symptoms in bakery and auto body shop workers: associations with exposure and respiratory symptoms.

    Science.gov (United States)

    Arrandale, Victoria; Meijster, Tim; Pronk, Anjoeka; Doekes, Gert; Redlich, Carrie A; Holness, D Linn; Heederik, Dick

    2013-02-01

    Despite the importance of skin exposure, studies of skin symptoms in relation to exposure and respiratory symptoms are rare. The goals of this study were to describe exposure-response relationships for skin symptoms, and to investigate associations between skin and respiratory symptoms in bakery and auto body shop workers. Data from previous studies of bakery and auto body shop workers were analyzed. Average exposure estimates for wheat allergen and isocyanates were used. Generalized linear models were constructed to describe the relationships between exposure and skin symptoms, as well as between skin and respiratory symptoms. Data from 723 bakery and 473 auto body shop workers were analyzed. In total, 5.3% of bakery and 6.1% of auto body shop workers were female; subjects' mean age was 39 and 38 years, respectively. Exposure-response relationships were observed in auto body shop workers for itchy or dry skin (PR 1.55, 95% CI 1.2-2.0) and work-related itchy skin (PR 1.97, 95% CI 1.2-3.3). A possible exposure-response relationship for work-related itchy skin in bakery workers did not reach statistical significance. In both groups, reporting skin symptoms was strongly and significantly associated with reporting respiratory symptoms, both work-related and non-work-related. Exposure-response relationships were observed for skin symptoms in auto body shop workers. The lack of significant exposure-response associations in bakery workers should be interpreted cautiously. Workers who reported skin symptoms were up to four times more likely to report respiratory symptoms. Improved awareness of both skin and respiratory outcomes in exposed workers is needed.

  16. Use of individual auto-injector kits 'IZAS-05' on the contemporary battlefield.

    Science.gov (United States)

    Ziemba, Radosław

    2012-01-01

    In crisis situations, such as transportation catastrophes, terrorist attacks or contamination with chemical warfare agents, it is crucial to properly organize and sensibly conduct rescue operations. Among chemical warfare agents, the most toxic ones are the derivatives of organophosphorus compounds. An individual auto-injector kit 'IZAS-05' contains auto-injectors, which are devices designed for intramuscular administration of drugs in self-aid or buddy-aid on the battlefield. This paper describes in detail the components of the 'IZAS-05' kit, as well as its mode of use and possible contraindications.

  17. Resolution of overlapping skin auto-fluorescence for development of non-invasive applications

    Science.gov (United States)

    Su, Yu-Zheng; Lin, Li-Wu; Chen, Chuen-Yau; Hung, Min-Wei; Huang, Kuo-Cheng

    2010-08-01

    Skin auto-fluorescence spectra can provide useful biological information, but the obtained spectrum is overlapped and is difficult to distinguish each contributed component. We applied the genetic algorithm to decompose the overlapping spectrum. First, we simulate the overlapping spectral to confirm our feasible algorithm. The skin auto-fluorescence spectra were obtained from the normal human skin with 337 nm excitation light source. The nicotinamide adenine dinucleotid (NADH) and flavin adenine dinucleotide (FAD) are accurately decomposed and demonstrated. The developed algorithm can be widely applied to achieve qualitative and quantitative analysis for overlapping spectra.

  18. Asynchronous teams for solving the loading and routing auto-carrier problem

    OpenAIRE

    Parolin, Erick Skorupa

    2016-01-01

    Orientador: Prof. Dr. Cláudio Nogueira de Meneses Dissertação (mestrado) - Universidade Federal do ABC, Programa de Pós-Graduação em Ciência da Computação, 2016. Beyond a complex real world system composed by a set of sophisticated machines and qualied human resources distributed around manufacturing environment, the Auto In- dustry needs a little more to allow their products to reach the nal costumers. Loading vehicles like cars, trucks and vans into auto-carriers and designin...

  19. Auto y heteroestereotipo étnico en estudiantes preuniversitarios de Lima Metropolitana

    Directory of Open Access Journals (Sweden)

    Carmen Zornoza

    1986-12-01

    Full Text Available La autora revisa algunas de las investigaciones hechas en el Perú acerca de la influencia de factores étnicos. Luego expone los resultados de una investigación acerca de auto y hetero estereotipos en grupos raciales diferentes.  Queda demostrado que el auto estereotipo de los blancos es más alto que el de los mestizos y que el hetero estereotipo de estos últimos es más alto que el de los primeros.

  20. Use of individual auto-injector kits ‘IZAS-05’ on the contemporary battlefield

    Science.gov (United States)

    Ziemba, Radosław

    2012-01-01

    Summary In crisis situations, such as transportation catastrophes, terrorist attacks or contamination with chemical warfare agents, it is crucial to properly organize and sensibly conduct rescue operations. Among chemical warfare agents, the most toxic ones are the derivatives of organophosphorus compounds. An individual auto-injector kit ‘IZAS-05’ contains auto-injectors, which are devices designed for intramuscular administration of drugs in self-aid or buddy-aid on the battlefield. This paper describes in detail the components of the ‘IZAS-05’ kit, as well as its mode of use and possible contraindications. PMID:22207129

  1. Long-term exposure to auto exhaust and other pollutant mixtures

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, T.E.; Moorman, W.J.; Yang, Y.; Stara, J.F.

    1974-08-01

    Research report:beagles were exposed 16 hr daily for 61 months to raw and photochemically reacted auto exhaust, nitrogen oxides, and sulfur, alone and in combination. exposure to nitrogen oxides reduced diffusion capacity and peak expiratory flow. raw exhaust and raw exhaust plus sulfur oxides produced pulmonary hyperinflation. irradiated auto exhaust also impaired ventilatory distribution. lung volumes, compliances, and maximal breathing capacity were not impaired by the experimental atmospheres. such chronic pulmonary changes resulting from long-term, low-level exposure to ubiquitous urban air pollutants denote potential, serious health hazards. (l diagram, 16 references, 3 tables)

  2. "Autos de Resistência" As an Instrument for Extermination Policy of the "Enemy"

    Directory of Open Access Journals (Sweden)

    Larissa Leilane Fontes de Lima

    2016-12-01

    Full Text Available The present article aims to analyze, through the study of "autos de resistência", its tensions with social inequality. From the understanding of the processes of criminalization - through a Marxist perspective - it was possible to make some observations about the social construction of the "enemy" to then understand how works the extermination policy of these sectors of society. The police structures in the Brazilian context of the "war on drugs", play a key role in the policy of extermination of the "enemy", which is made possible by the "autos de resistência".

  3. Auto-eficacia docente, motivaci??n intr??nseca y expectativa de resultado de alumnado

    OpenAIRE

    Revelli Galarza, Joel Andr??s; Guti??rrez Sede??o, Pablo; Castillo Fern??ndez, Federico del; Centeno Mudarra, Mar??a; Vinuesa Gonz??lez, Alejandro; Belcaid, Basma; Andrade Robles, Mar??a Teresa

    2013-01-01

    La Teor??a Social-Cognitiva de Bandura da gran importancia a la auto-eficacia como m??todo regulador del aprendizaje y sus diferentes elementos, como la motivaci??n y la expectativa de resultado. Por ello, el objetivo de este estudio es determinar en qu?? grado se relacionan ambos constructos en un contexto universitario y como la motivaci??n intr??nseca afecta la expectativa de resultado en alumnos. Para ello se han pasado cuestionarios de auto-eficacia a tres profesores, y cuestionarios de ...

  4. Inflation and deflation timing of the AutoCAT 2 WAVE intra-aortic balloon pump using the autoPilot mode in a clinical setting.

    Science.gov (United States)

    Bakker, E W M; Visser, K; van der Wal, A; Kuiper, M A; Koopmans, M; Breedveld, R

    2012-09-01

    The primary goal of this observational clinical study was to register the occurrence of incorrect inflation and deflation timing of an intra-aortic balloon pump in autoPilot mode. The secondary goal was to identify possible causes of incorrect timing. During IABP assistance of 60 patients, every four hours a strip was printed with the IABP frequency set to 1:2. Strips were examined for timing discrepancies beyond 40 ms from the dicrotic notch (inflation) and the end of the diastolic phase (deflation). In this way, 320 printed strips were examined. A total of 52 strips (16%) showed incorrect timing. On 24 of these strips, the incorrect timing was called incidental, as it showed on only one or a few beats. The other 28 cases of erroneous timing were called consistent, as more than 50% of the beats on the strip showed incorrect timing. We observed arrhythmia in 69% of all cases of incorrect timing. When timing was correct, arrhythmia was found on 13 (5%) of 268 strips. A poor quality electrocardiograph (ECG) signal showed on 37% of all strips with incorrect timing and 11% of all strips with proper timing. We conclude that inflation and deflation timing of the IABP is not always correct when using the autoPilot mode. The quality of the ECG input signal and the occurrence of arrhythmia appear to be related to erroneous timing. Switching from autoPilot mode to operator mode may not always prevent incorrect timing.

  5. Modeling Defects, Shape Evolution, and Programmed Auto-origami in Liquid Crystal Elastomers

    Directory of Open Access Journals (Sweden)

    Andrew eKonya

    2016-06-01

    Full Text Available Liquid crystal elastomers represent a novel class of programmable shape-transforming materials whose shape change trajectory is encoded in the material’s nematic director field. Using three-dimensional nonlinear finite element elastodynamics simulation, we model a variety of different actuation geometries and device designs: thin films containing topological defects, patterns that induce formation of folds and twists, and a bas-relief structure. The inclusion of finite bending energy in the simulation model reveals features of actuation trajectory that may be absent when bending energy is neglected. We examine geometries with a director pattern uniform through the film thickness encoding multiple regions of positive Gaussian curvature. Simulations indicate that heating such a system uniformly produces a disordered state with curved regions emerging randomly in both directions due to the film’s up/down symmetry. By contrast, applying a thermal gradient by heating the material first on one side breaks up/down symmetry and results in a deterministic trajectory producing a more ordered final shape. We demonstrate that a folding zone design containing cut-out areas accommodates transverse displacements without warping or buckling; and demonstrate that bas-relief and more complex bent/twisted structures can be assembled by combining simple design motifs.

  6. Determination of Required Skills Necessary for Job Entry Level of Employment in the Auto Body Trade. Final Report.

    Science.gov (United States)

    Schindler, John; And Others

    A study to identify the basic skills and tasks that are necessary to obtain job-entry level employment as an auto body technician was conducted at the Southwest Wisconsin Vocational-Technical Institute from March to July 1975. Surveys were distributed to employees, vocational graduates, and employers in the auto body trade. The survey determined…

  7. Auto-SCT improves survival in systemic light chain amyloidosis: a retrospective analysis with 14-year follow-up.

    Science.gov (United States)

    Parmar, S; Kongtim, P; Champlin, R; Dinh, Y; Elgharably, Y; Wang, M; Bashir, Q; Shah, J J; Shah, N; Popat, U; Giralt, S A; Orlowski, R Z; Qazilbash, M H

    2014-08-01

    Optimal treatment approach continues to remain a challenge for systemic light chain amyloidosis (AL). So far, Auto-SCT is the only modality associated with long-term survival. However, failure to show survival benefit in randomized study raises questions regarding its efficacy. We present a comparative outcome analysis of Auto-SCT to conventional therapies (CTR) in AL patients treated over a 14-year period at our institution. Out of the 145 AL amyloidosis patients, Auto-SCT was performed in 80 patients with 1-year non-relapse mortality rate of 12.5%. Novel agents were used as part of induction therapy in 56% of transplant recipients vs 46% of CTR patients. Hematological and organ responses were seen in 74.6% and 39% in the Auto-SCT arm vs 53% and 12% in the CTR arm, respectively. The projected 5-year survival for Auto-SCT vs CTR was 63% vs 38%, respectively. Landmark analysis of patients alive at 1-year after diagnosis showed improved 5-year OS of 72% with Auto-SCT vs 65% in the CTR arm. In the multivariate analysis, age Auto-SCT were associated with improved survival. In conclusion, Auto-SCT is associated with long-term survival for patients with AL amyloidosis.

  8. A AUTO-ESTIMA EM ADOLESCENTES COM E SEM FISSURAS DE LÁBIO E/OU DE PALATO

    Directory of Open Access Journals (Sweden)

    Andrade Denise de

    2001-01-01

    Full Text Available O auto-conceito é um determinante importante da auto-estima, entre homens e mulheres, isto nos fez refletir sobre o processo de reabilitação das pessoas portadoras de malformação. Utilizamos para mensurar o nível de auto-estima a escala de Janis e Field. Entrevistou-se 608 adolescentes sendo 235 com e 373 sem fissuras de lábio e/ou de palato, entre idades de 17 a 20 anos e de ambos o sexos. Analisando os níveis de auto-estima concluímos que o grupo de adolescentes com fissuras se comporta de forma diferente do grupo sem fissura, ou seja, os portadores de fissuras exibem menores escores de auto-estima.

  9. Epinephrine auto-injector use in adolescents at risk of anaphylaxis: a qualitative study in Scotland, UK.

    Science.gov (United States)

    Gallagher, M; Worth, A; Cunningham-Burley, S; Sheikh, A

    2011-06-01

    Adolescents with severe allergies are at particular risk of severe and fatal anaphylactic reactions. Epinephrine (adrenaline) is known to be under-utilized by teenagers. We sought to gain knowledge of adolescents' attitudes towards and experience of epinephrine auto-injectors in order to inform improvements in patient education. A qualitative study of adolescents in Scotland, UK with a history of anaphylaxis and their parents. In-depth interviews explored adolescents' accounts of anaphylactic reactions, including issues related to using epinephrine auto-injectors. Focus groups with adolescents and parents were used to discuss interventions to improve adolescent self-management of anaphylaxis. Twenty-six adolescents and 28 parents were interviewed. Eight adolescents and 10 parents participated in separate focus groups. Most adolescents had not used the auto-injector in an anaphylactic emergency. We identified multi-faceted barriers to use, including: failure to recognize anaphylaxis; uncertainty about auto-injector technique and when to administer it; fear of using the auto-injector. Most adolescents reported carrying auto-injectors some of the time, though several found this inconvenient due to the size; only one reported non-use of an auto-injector because it had not been carried. Adolescents and parents reported under-use of epinephrine auto-injectors. Carriage is insufficient to ensure that auto-injectors are used. Barriers to use are multiple and complex, and unlikely to be overcome using simple educational interventions. Auto-injector training currently offered is often inadequate preparation for an emergency. A more comprehensive approach is needed, addressing the psychosocial dimensions of anaphylactic emergencies as well as treatment. Training should ideally be provided by specialist allergists or nurses, but can also be provided and reinforced in primary care. © 2011 Blackwell Publishing Ltd.

  10. Flow Forecasting in Drainage Systems with Extrapolated Radar Rainfall Data and Auto Calibration on Flow Observations

    DEFF Research Database (Denmark)

    Thorndahl, Søren Liedtke; Grum, M.; Rasmussen, Michael R.

    2011-01-01

    in a small urban catchment has been developed. The forecast is based on application of radar rainfall data, which by a correlation based technique, is extrapolated with a lead time up to two hours. The runoff forecast in the drainage system is based on a fully distributed MOUSE model which is auto...

  11. Come diventare una Rockstar. Gli Houser e l’evoluzione del franchise Grand Theft Auto.

    Directory of Open Access Journals (Sweden)

    Federico Giordano

    2013-03-01

    Full Text Available Wanted. La storia criminale di Grand Theft Auto, Multiplayer, 2012, il libro scritto da David Kushner, giornalista e docente universitario già autore del precedente, molto apprezzato, Master of Doom, è un testo importante per gli studi sui videogiochi, nonostante non si presenti in apparenza – a partire dal titolo evocativo – come testo accademico.

  12. Optimal Operation of Microgrids Considering Auto-Configuration Function Using Multiagent System

    Directory of Open Access Journals (Sweden)

    Van-Hai Bui

    2017-09-01

    Full Text Available Monitoring the status of existing devices and identification of newly added devices is required in microgrids to adjust the operation schedule followed by any event or integration of a new device. Therefore, in this paper, automatic reconfiguration of microgrids is considered after the addition of a new device or change in the operation status of an existing device by using a multiagent system. This capability of the microgrid is named as auto-configuration function, which is performed by the auto-configurator agent. In case of addition of a new device, the auto-configurator agent is responsible for authorization and registration of the newly added device. In case of change in status of any existing device, the status information is updated. After integration of a new device or change in status of an existing device, re-optimization is carried out by the energy management system (EMS agent. Agent communication language (ACL is used to develop a modified contract net protocol (MCNP for communication among different agents. EMS agent and auto-configurator agent exchange information for economic rescheduling of the microgrid components. Simulation results have shown that the proposed method can be used for optimal operation of microgrids when the configuration changes due to the addition/removal of a device.

  13. An Auto Tuning Substation Peak Shaving Controller for Congestion Management Using Flexible Demand

    DEFF Research Database (Denmark)

    Sossan, Fabrizio; Marinelli, Mattia

    2013-01-01

    A closed loop substation peak shaving/congestion management controller for radial distribution networks is presented. The controller it uses an individual control signal in order to shift the consumption of a population of demand side resources, DSRs. The controller auto tunes its parameters on...

  14. The Li(f)e of the Self: Missing Persons and Auto/Archeological Excavations

    Science.gov (United States)

    Burdick, Jake

    2014-01-01

    This article describes and enacts a process of autobiographical inquiry, auto/archeology, which seeks to address problematic confluences of memory and identity in reconstructing one's historical narrative. Drawing on curriculum theory and Lacanian psychoanalysis, the author describes a process of excavation in which understandings of a prior…

  15. The ZeroAccess Auto-Clicking and Search-Hijacking Click Fraud Modules

    Science.gov (United States)

    2013-12-16

    payloads and instead began distributing Bitcoin miners and click fraud modules.3 From a technical perspective, the primary click fraud malware used in...this era operated in the indiscriminate “auto-clicking” fashion we describe in Section 5. Alongside the click fraud and Bitcoin payloads, ZeroAccess

  16. Auto-parametric semi-trivial and post-critical response of a spherical pendulum damper

    Czech Academy of Sciences Publication Activity Database

    Náprstek, Jiří; Fischer, Cyril

    2009-01-01

    Roč. 87, 19-20 (2009), s. 1204-1215 ISSN 0045-7949 R&D Projects: GA ČR(CZ) GA103/06/0099 Institutional research plan: CEZ:AV0Z20710524 Keywords : non-linear vibration * spherical pendulum * auto-parametric systems Subject RIV: JM - Building Engineering Impact factor: 1.440, year: 2009

  17. Heating and Air Conditioning. Auto Mechanics Curriculum Guide Module 9. Instructor's Guide.

    Science.gov (United States)

    Hevel, David

    This unit of instruction is one of a series of modules in the Missouri Auto Mechanics Curriculum Guide. The module's format was developed for competency-based teaching and testing. The module contains 11 units, each of which contains the following components: a competency profile, objective sheets, references, notes to the instructor, lesson…

  18. Soliton Coupling Driven by Phase Fluctuations in Auto-Parametric Resonance

    CERN Document Server

    Binder, B

    2002-01-01

    In this paper the interaction of sine-Gordon solitons and mediating linear waves is modelled by a special case of auto-parametric resonance, the Rayleigh-type self-excited non-linear autonomous system driven by a statistical phase gradient related to the soliton energy. Spherical symmetry can stimulate "whispering gallery modes" (WGM) with integral coupling number M=137.

  19. Distress, problems and supportive care needs of patients treated with auto- or allo-SCT

    NARCIS (Netherlands)

    Braamse, A.M.J.; van Meijel, B.; Visser, O.; Huijgens, P.C.; Beekman, A.T.F.; Dekker, J.

    2014-01-01

    Hematological malignancies and treatment with hematopoietic SCT are known to affect patients' quality of life. The problem profile and care needs of this patient group need clarification, however. This study aimed to assess distress, problems and care needs after allo-or auto-SCT, and to identify

  20. Anemia Hemolítica Auto-Imune - Caso Clínico

    OpenAIRE

    Correia, T; Ferreira, A; Almeida, T

    2004-01-01

    A anemia hemolitica é uma entidade caracterizada por destruição dos glóbulos vermelhos mediada por auto-anticorpos. Os mecanismos fisiopatológicos ainda nao estão completamente compreendidos e a terapêutica é controversa.Os autores apresentam este caso pela sua particular evolução/resposta terapêutica.

  1. Item Response Theory analysis of the Autonomy over Tobacco Scale (AUTOS).

    Science.gov (United States)

    Wellman, Robert J; Edelen, Maria Orlando; DiFranza, Joseph R

    2015-06-01

    The Autonomy over Tobacco Scale (AUTOS) is composed of 12-symptoms of nicotine dependence. While it has demonstrated excellent reliability and validity, several psychometric properties have yet to be investigated. We aimed to determine (1) whether items functioned differently across demographic groups, (2) the likelihood that individual symptoms would be endorsed by smokers at different levels of diminished autonomy, and (3) the degree of information provided by each item and the reliability of the full AUTOS across the range of diminished autonomy. Data for this study come from two convenience samples of American adult current smokers (n=777; 69% female; 88% white; Mage=34 years, range: 18-78), of whom 66% were daily smokers (Mcigarettes/smoking day=10.1, range: autonomy. The AUTOS maintains acceptable reliability (>0.70) across the range of diminished autonomy within which more than 95% of smokers' scores could be anticipated to fall. The AUTOS is a versatile and psychometrically sound instrument for measuring the loss of autonomy over tobacco use. Copyright © 2015 Elsevier Ltd. All rights reserved.

  2. Auto-estima dos alunos de graduação de enfermagem

    Directory of Open Access Journals (Sweden)

    Lucila Amaral Carneiro Vianna

    2002-10-01

    Full Text Available Este estudo avalia a auto-estima dos alunos de Graduação em Enfermagem, que por meio da Oficina desenvolvem mecanismos para melhoria da auto-estima, acreditando ser a fase mais propícia para se tornarem multiplicadores das ações de saúde. METODOLOGIA: foi realizado com 156 alunos do 3º ano. Foram utilizadas técnicas do sociodrama, da neurolingüística e a avaliação foi elaborada segundo Minayo. Foi possível verificar que a auto-estima é normalmente confundida com a auto-imagem e estas são estereotipadas, em ambos os sexos. Por estar voltado e preocupado com o bem estar e a qualidade de vida do cliente / paciente, o profissional de enfermagem negligencia a si próprio. Neste caso, a Oficina, foi essencial para que os alunos pudessem resgatar maior conhecimento interior sobre si, e que para prestar assistência eficaz aos clientes/pacientes, devem estar saudáveis física e psicologicamente.

  3. Research on AutoCAD secondary development and function expansion based on VBA technology

    Science.gov (United States)

    Zhang, Runmei; Gu, Yehuan

    2017-06-01

    AutoCAD is the most widely used drawing tool among the similar design drawing products. In the process of drawing different types of design drawings of the same product, there are a lot of repetitive and single work contents. The traditional manual method uses a drawing software AutoCAD drawing graphics with low efficiency, high error rate and high input cost shortcomings and many more. In order to solve these problems, the design of the parametric drawing system of the hot-rolled I-beam (steel beam) cross-section is completed by using the VBA secondary development tool and the Access database software with large-capacity storage data, and the analysis of the functional extension of the plane drawing and the parametric drawing design in this paper. For the secondary development of AutoCAD functions, the system drawing work will be simplified and work efficiency also has been greatly improved. This introduction of parametric design of AutoCAD drawing system to promote the industrial mass production and related industries economic growth rate similar to the standard I-beam hot-rolled products.

  4. Epinephrine auto-injector prescriptions to food-allergic patients in primary care in The Netherlands

    NARCIS (Netherlands)

    Saleh-Langenberg, Jacquelien; Dubois, A. E. J.; Groenhof, F.; Kocks, J. W. H.; van der Molen, T.; Flokstra-de Blok, B. M. J.

    2015-01-01

    Background: The knowledge of general practitioner(s) (GPs) regarding food allergy and anaphylaxis and practices in the prescription of epinephrine auto-injector(s) (EAIs) among GPs has previously only been studied using questionnaires and hypothetical cases. Therefore, there are currently no data as

  5. Economic Development Policymaking Down the Global Commodity Chain: Attracting an Auto Industry to Silao, Mexico

    Science.gov (United States)

    Rothstein, Jeffrey S.

    2005-01-01

    This article applies the global commodity chain approach to analyze the way policymakers encouraged an automotive commodity chain to touch down in Silao, Mexico. The article explains that the changing dynamics of the global auto industry have transformed it into an "assembler-driven" commodity chain. It notes how policymakers in the…

  6. Disrupted Auto-Activation, Dysexecutive and Confabulating Syndrome Following Bilateral Thalamic and Right Putaminal Stroke

    Directory of Open Access Journals (Sweden)

    Lieve De Witte

    2008-01-01

    Full Text Available Objective: Clinical, neuropsychological, structural and functional neuroimaging results are reported in a patient who developed a unique combination of symptoms after a bi-thalamic and right putaminal stroke. The symptoms consisted of dysexecutive disturbances associated with confabulating behavior and auto-activation deficits. Background: Basal ganglia and thalamic lesions may result in a variety of motor, sensory, neuropsychological and behavioral syndromes. However, the combination of a dysexecutive syndrome complicated at the behavioral level with an auto-activation and confabulatory syndrome has never been reported. Methods: Besides clinical and neuroradiological investigations, an extensive set of standardized neuropsychological tests was carried out. Results: In the post-acute phase of the stroke, a dysexecutive syndrome was found in association with confabulating behavior and auto-activation deficits. MRI showed focal destruction of both thalami and the right putamen. Quantified ECD SPECT revealed bilateral hypoperfusions in the basal ganglia and thalamus but no perfusion deficits were found at the cortical level. Conclusion: The combination of disrupted auto-activation, dysexecutive and confabulating syndrome in a single patient following isolated subcortical damage renders this case exceptional. Although these findings do not reveal a functional disruption of the striato-ventral pallidal-thalamic-frontomesial limbic circuitry, they add to the understanding of the functional role of the basal ganglia in cognitive and behavioral syndromes.

  7. Engine Performance (Section C: Emission Control Systems). Auto Mechanics Curriculum Guide. Module 3. Instructor's Guide.

    Science.gov (United States)

    Rains, Larry

    This engine performance (emission control systems) module is one of a series of competency-based modules in the Missouri Auto Mechanics Curriculum Guide. Topics of this module's five units are: positive crankcase ventilation (PCV) and evaporative emission control systems; exhaust gas recirculation (EGR); air injection and catalytic converters;…

  8. Auto-ubiquitination of Mdm2 Enhances Its Substrate Ubiquitin Ligase Activity*

    Science.gov (United States)

    Ranaweera, Ruchira S.; Yang, Xiaolu

    2013-01-01

    The RING domain E3 ubiquitin ligase Mdm2 is the master regulator of the tumor suppressor p53. It targets p53 for proteasomal degradation, restraining the potent activity of p53 and enabling cell survival and proliferation. Like most E3 ligases, Mdm2 can also ubiquitinate itself. How Mdm2 auto-ubiquitination may influence its substrate ubiquitin ligase activity is undefined. Here we show that auto-ubiquitination of Mdm2 is an activating event. Mdm2 that has been conjugated to polyubiquitin chains, but not to single ubiquitins, exhibits substantially enhanced activity to polyubiquitinate p53. Mechanistically, auto-ubiquitination of Mdm2 facilitates the recruitment of the E2 ubiquitin-conjugating enzyme. This occurs through noncovalent interactions between the ubiquitin chains on Mdm2 and the ubiquitin binding domain on E2s. Mutations that diminish the noncovalent interactions render auto-ubiquitination unable to stimulate Mdm2 substrate E3 activity. These results suggest a model in which polyubiquitin chains on an E3 increase the local concentration of E2 enzymes and permit the processivity of substrate ubiquitination. They also support the notion that autocatalysis may be a prevalent mode for turning on the activity of latent enzymes. PMID:23671280

  9. Deutschland hält Führungsrolle bei Patenten für autonome Autos

    OpenAIRE

    Bardt, Hubertus

    2017-01-01

    Auf der Internationalen Automobilausstellung IAA im September in Frankfurt werden die beiden großen Trends der Autoindustrie eine zentrale Rolle spielen: Die Entwicklung umweltfreundlicher Technologien zum einen und die Digitalisierung des Autos auf der anderen Seite. Beide Trends werden die Autoindustrie nachhaltig verändern.

  10. Internationalization of the auto industry in the conditions of national economies growth

    Directory of Open Access Journals (Sweden)

    Tetiana Laduba

    2010-12-01

    Full Text Available In the article were studied the strategies, models and forms of the auto industry internationalization in the conditions of integration processes development and growth of the national economies transparency level. The authors determined the factors and grounded the criteria of effective strategies implementation of automobile companies of the USA, Japan, the EU and China.

  11. A QR code identification technology in package auto-sorting system

    Science.gov (United States)

    di, Yi-Juan; Shi, Jian-Ping; Mao, Guo-Yong

    2017-07-01

    Traditional manual sorting operation is not suitable for the development of Chinese logistics. For better sorting packages, a QR code recognition technology is proposed to identify the QR code label on the packages in package auto-sorting system. The experimental results compared with other algorithms in literatures demonstrate that the proposed method is valid and its performance is superior to other algorithms.

  12. Iterative model-building, structure refinement, and density modification with the PHENIX AutoBuild Wizard

    Energy Technology Data Exchange (ETDEWEB)

    Los Alamos National Laboratory, Mailstop M888, Los Alamos, NM 87545, USA; Lawrence Berkeley National Laboratory, One Cyclotron Road, Building 64R0121, Berkeley, CA 94720, USA; Department of Haematology, University of Cambridge, Cambridge CB2 0XY, England; Terwilliger, Thomas; Terwilliger, T.C.; Grosse-Kunstleve, Ralf Wilhelm; Afonine, P.V.; Moriarty, N.W.; Zwart, P.H.; Hung, L.-W.; Read, R.J.; Adams, P.D.

    2007-04-29

    The PHENIX AutoBuild Wizard is a highly automated tool for iterative model-building, structure refinement and density modification using RESOLVE or TEXTAL model-building, RESOLVE statistical density modification, and phenix.refine structure refinement. Recent advances in the AutoBuild Wizard and phenix.refine include automated detection and application of NCS from models as they are built, extensive model completion algorithms, and automated solvent molecule picking. Model completion algorithms in the AutoBuild Wizard include loop-building, crossovers between chains in different models of a structure, and side-chain optimization. The AutoBuild Wizard has been applied to a set of 48 structures at resolutions ranging from 1.1 {angstrom} to 3.2 {angstrom}, resulting in a mean R-factor of 0.24 and a mean free R factor of 0.29. The R-factor of the final model is dependent on the quality of the starting electron density, and relatively independent of resolution.

  13. Iterative model building, structure refinement and density modification with the PHENIX AutoBuild wizard.

    Science.gov (United States)

    Terwilliger, Thomas C; Grosse-Kunstleve, Ralf W; Afonine, Pavel V; Moriarty, Nigel W; Zwart, Peter H; Hung, Li Wei; Read, Randy J; Adams, Paul D

    2008-01-01

    The PHENIX AutoBuild wizard is a highly automated tool for iterative model building, structure refinement and density modification using RESOLVE model building, RESOLVE statistical density modification and phenix.refine structure refinement. Recent advances in the AutoBuild wizard and phenix.refine include automated detection and application of NCS from models as they are built, extensive model-completion algorithms and automated solvent-molecule picking. Model-completion algorithms in the AutoBuild wizard include loop building, crossovers between chains in different models of a structure and side-chain optimization. The AutoBuild wizard has been applied to a set of 48 structures at resolutions ranging from 1.1 to 3.2 A, resulting in a mean R factor of 0.24 and a mean free R factor of 0.29. The R factor of the final model is dependent on the quality of the starting electron density and is relatively independent of resolution.

  14. Auto-inhibition and phosphorylation-induced activation of PLC-γ isozymes

    Science.gov (United States)

    Hajicek, Nicole; Charpentier, Thomas H.; Rush, Jeremy R.; Harden, T. Kendall; Sondek, John

    2013-01-01

    Multiple extracellular stimuli, such as growth factors and antigens, initiate signaling cascades through tyrosine phosphorylation and activation of phospholipase C (PLC)-γ isozymes. Like most other PLCs, PLC-γ1 is basally auto-inhibited by its X-Y linker, which separates the X-and Y-boxes of the catalytic core. The C-terminal SH2 (cSH2) domain within the X-Y linker is the critical determinant for auto-inhibition of phospholipase activity. Release of auto-inhibition requires an intramolecular interaction between the cSH2 domain and a phosphorylated tyrosine, Tyr783, also located within the X-Y linker. The molecular mechanisms that mediate auto-inhibition and phosphorylation-induced activation have not been defined. Here, we describe structures of the cSH2 domain both alone and bound to a PLC-γ1 peptide encompassing phosphorylated Tyr783. The cSH2 domain remains largely unaltered by peptide engagement. Point mutations in the cSH2 domain located at the interface with the peptide were sufficient to constitutively activate PLC-γ1 suggesting that peptide engagement directly interferes with the capacity of the cSH2 domain to block the lipase active site. This idea is supported by mutations in a complimentary surface of the catalytic core that also enhanced phospholipase activity. PMID:23777354

  15. Variational Gaussian Process Auto-Encoder for Ordinal Prediction of Facial Action Units

    NARCIS (Netherlands)

    Eleftheriadis, Stefanos; Rudovic, Ognjen; Deisenroth, Marc Peter; Pantic, Maja; Lai, Shang-Hong; Lepetit, Vincent; Nishino, Ko; Sato, Yoichi

    2016-01-01

    We address the task of simultaneous feature fusion and modeling of discrete ordinal outputs. We propose a novel Gaussian process (GP) auto-encoder modeling approach. In particular, we introduce GP encoders to project multiple observed features onto a latent space, while GP decoders are responsible

  16. Comparative and International Learning from Vanuatu Research Moratoria: A Plurilevel, Plurilocal Researcher's Auto-Ethnography

    Science.gov (United States)

    McCormick, Alexandra

    2017-01-01

    In this article, I offer a reflexive auto-ethnography to revisit questions about knowledge and research practices in international contexts, influenced differently by aspects of globalization. Specifically, I position my experience of the Vanuatu research moratorium on "foreign" researchers of 2013/2014 as a lynchpin to analyse and…

  17. Footy, Gangs and Love: Using Auto-Ethnography to Problematise Practice on a Practicum

    Science.gov (United States)

    Bellamy, Roz

    2017-01-01

    This article was written as an auto ethnography, which allowed for a complex and personal exploration of professional standards, teachers' professional identities, neoliberal reforms, and approaches to literacy and creativity. This article reflects on a practicum which involved teaching Romeo and Juliet to two year nine classes at an all boys'…

  18. DESIGN AND DEVELOPMENT OF AUTO DEPTH CONTROL OF REMOTELY OPERATED VEHICLE USING THRUSTER SYSTEM

    Directory of Open Access Journals (Sweden)

    F.A. Ali

    2014-12-01

    Full Text Available Remotely Operated Vehicles are underwater robots designed specifically for surveillance, monitoring and collecting data for underwater activities. In the underwater vehicle industries, the thruster is an important part in controlling the direction, depth and speed of the ROV. However, there are some ROVs that cannot be maintained at the specified depth for a long time because of disturbance. This paper proposes an auto depth control using a thruster system. A prototype of a thruster with an auto depth control is developed and attached to the previously fabricated UTeM ROV. This paper presents the operation of auto depth control as well as thrusters for submerging and emerging purposes and maintaining the specified depth. The thruster system utilizes a microcontroller as its brain, a piezoresistive strain gauge pressure sensor and a DC brushless motor to run the propeller. Performance analysis of the auto depth control system is conducted to identify the sensitivity of the pressure sensor, and the accuracy and stability of the system. The results show that the thruster system performs well in maintaining a specified depth as well as stabilizing itself when a disturbanceoccurs even with a simple proportional controller used to control the thruster, where the thruster is an important component of the ROV.

  19. La Tarea de Auto-consuelo Compasivo en Terapia Focalizada en la Emoción

    National Research Council Canada - National Science Library

    Ciro Caro; Teresa Hornillos

    2015-01-01

    El objetivo de este artículo es poner a disposición de los terapeutas y de los equipos de investigación clínica en psicoterapia, el conocimiento actualizado sobre la Tarea de Auto-consuelo Compasivo de la Terapia Focalizada...

  20. A teoria do auto-cuidado e sua aplicabilidade no sistema de alojamento conjunto

    Directory of Open Access Journals (Sweden)

    Adriana Remor

    1986-09-01

    Full Text Available O trabalho se refere à aplicação da teoria do OREM no sistema de alojamento conjunto, visando determinar as deficiências das capacidades dos indivíduos para execução de medidas de auto-cuidado.

  1. Auto-Communication and Micro-Orientalism at the Shanghai Expo 2010

    DEFF Research Database (Denmark)

    Ren, Carina Bregnholm; Ooi, Can-Seng

    Using the concepts of auto-communication and micro-orientalism, this article argues that nation branding at World Expos produces and propagates notions of difference and otherness. By use of the Danish ‘Welfairytales’ pavilion at the 2010 Expo in Shanghai, we show how national Self is performed...

  2. Biochemical and Ultrastructural Changes in Sida cordifolia L. and Catharanthus roseus L. to Auto Pollution.

    Science.gov (United States)

    Verma, Vijeta; Chandra, Neelam

    2014-01-01

    Auto pollution is the by-product of our mechanized mobility, which adversely affects both plant and human life. However, plants growing in the urban locations provide a great respite to us from the brunt of auto pollution by absorbing the pollutants at their foliar surface. Foliar surface configuration and biochemical changes in plant species, namely, Sida cordifolia L. and Catharanthus roseus L. grown at roadside (polluted site 1, Talkatora; polluted site 2, Charbagh) in Lucknow city and in the garden of the university campus, which has been taken as reference site, were investigated. It was observed that air pollution caused by auto exhaust showed marked alterations in photosynthetic pigments (chlorophyll, carotenoid, and phaeophytin), and relative water content was reduced while antioxidative enzymes like catalase and peroxidase were found to be enhanced. The changes in the foliar configuration reveal marked alteration in epidermal traits, with decreased number of stomata, stomatal indices, and epidermal cells per unit area, while length and breadth of stomata and epidermal cells were found to be increased in leaves samples wich can be used as biomarkers of auto pollution.

  3. Convolutional auto-encoder for image denoising of ultra-low-dose CT

    Directory of Open Access Journals (Sweden)

    Mizuho Nishio

    2017-08-01

    Conclusion: Neural network with convolutional auto-encoder could be trained using pairs of standard-dose and ultra-low-dose CT image patches. According to the visual assessment by radiologists and technologists, the performance of our proposed method was superior to that of large-scale nonlocal mean and block-matching and 3D filtering.

  4. A free-boundary value problem related to auto ignition of ...

    African Journals Online (AJOL)

    We examine a free boundary value problem related to auto ignition of combustible fluid in insulation materials. The criteria for the existence of similarity solution of the model equations are established. The conditions for the existence of unique solution are also stated. The numerical results which show the influence of ...

  5. Auto-tuning Stencil Computations on Multicore and Accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Datta, Kaushik [Univ. of California, Berkeley, CA (United States); Williams, Samuel [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Volkov, Vasily [Univ. of California, Berkeley, CA (United States); Carter, Jonathan [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Oliker, Leonid [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Shalf, John [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Yelick, Katherine [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2010-12-07

    The recent transformation from an environment where gains in computational performance came from increasing clock frequency and other hardware engineering innovations, to an environment where gains are realized through the deployment of ever increasing numbers of modest performance cores has profoundly changed the landscape of scientific application programming. This exponential increase in core count represents both an opportunity and a challenge: access to petascale simulation capabilities and beyond will require that this concurrency be efficiently exploited.

  6. [Thyroiditis and gluten intolerance: extrapancreatic auto-immune diseases associated with type 1 diabetes].

    Science.gov (United States)

    Faesch, S; Jennane, F; Izembart, I; Chatenoud, L; Taupin, P; Martin, D; Polak, M; Robert, J-J

    2007-01-01

    This study aimed at evaluating the screening of thyroïditis and coeliac disease, in a population of children and adolescents with type 1 diabetes, and at comparing the appearance of antibodies specific for these 2 diseases as a function of age. The study included 370 children and adolescents, 179 girls and 191 boys, aged 13.8 +/- 4.4 yr and with diabetes for 7.1 +/- 3.8 yr. Auto-immune thyroïditis was screened using antimicrosomal and antithyroglobulin auto-antibodies, at a mean rhythm of 3 tests per patient (1 every 2 yr), associated with dosages of TSH and FT4. Coeliac disease was screened using antigliadin (+/- antiendomysium) auto-antibodies, at a mean rhythm of 2 tests per patient, and was confirmed by duodenojejunal biopsy. Antithyroïd auto-antibodies were correlated with age following the "censured data analysis" type approach. Antithyroïd autoantibodies were found in 42 patients (11.4%), of whom 9 were treated for hypothyroïdism and 1 for Basedow disease, and coeliac disease autoantibodies were found in 9 patients (3.2% of tested patients). The cumulated frequency of antithyroïd auto-antibodies increased regularly with age and was significantly higher in girls, reaching 28% in girls and 12% in boys around 18 yr of age. As a consequence of this evolution, antithyroïd auto-antibodies were frequently found at the time of diagnosis of diabetes when it declared after 10 yr of age, while they often became positive secondarily when diabetes occurred before 10 yr of age. Coeliac disease specific auto-antibodies appeared much earlier and were found at the time of diagnosis of diabetes or at the first screening test. Antithyroïd autoantibodies are increasingly frequent with age in children with type 1 diabetes, and become very elevated in girls. The rhythm for screening should be adapted to this evolution of autoantibodies with age, which is very different between thyroïditis and coeliac disease.

  7. Effect of external PEEP in patients under controlled mechanical ventilation with an auto-PEEP of 5?cmH2O or higher.

    OpenAIRE

    Natalini, G; Tuzzo, D; Rosano, A.; Testa, M; Grazioli, M.; Pennestr?, V; Amodeo, G.; Berruto, F.; Fiorillo, M; Peratoner, A; Tinnirello, A.; Filippini, M; Marsilia, PF; Minelli, C; Bernardini, A

    2016-01-01

    Background In some patients with auto-positive end-expiratory pressure (auto-PEEP), application of PEEP lower than auto-PEEP maintains a constant total PEEP, therefore reducing the inspiratory threshold load without detrimental cardiovascular or respiratory effects. We refer to these patients as ?complete PEEP-absorbers.? Conversely, adverse effects of PEEP application could occur in patients with auto-PEEP when the total PEEP rises as a consequence. From a pathophysiological perspective, all...

  8. AutoBD: Automated Bi-Level Description for Scalable Fine-Grained Visual Categorization.

    Science.gov (United States)

    Yao, Hantao; Zhang, Shiliang; Yan, Chenggang; Zhang, Yongdong; Li, Jintao; Tian, Qi

    Compared with traditional image classification, fine-grained visual categorization is a more challenging task, because it targets to classify objects belonging to the same species, e.g., classify hundreds of birds or cars. In the past several years, researchers have made many achievements on this topic. However, most of them are heavily dependent on the artificial annotations, e.g., bounding boxes, part annotations, and so on. The requirement of artificial annotations largely hinders the scalability and application. Motivated to release such dependence, this paper proposes a robust and discriminative visual description named Automated Bi-level Description (AutoBD). "Bi-level" denotes two complementary part-level and object-level visual descriptions, respectively. AutoBD is "automated," because it only requires the image-level labels of training images and does not need any annotations for testing images. Compared with the part annotations labeled by the human, the image-level labels can be easily acquired, which thus makes AutoBD suitable for large-scale visual categorization. Specifically, the part-level description is extracted by identifying the local region saliently representing the visual distinctiveness. The object-level description is extracted from object bounding boxes generated with a co-localization algorithm. Although only using the image-level labels, AutoBD outperforms the recent studies on two public benchmark, i.e., classification accuracy achieves 81.6% on CUB-200-2011 and 88.9% on Car-196, respectively. On the large-scale Birdsnap data set, AutoBD achieves the accuracy of 68%, which is currently the best performance to the best of our knowledge.Compared with traditional image classification, fine-grained visual categorization is a more challenging task, because it targets to classify objects belonging to the same species, e.g., classify hundreds of birds or cars. In the past several years, researchers have made many achievements on this topic

  9. SHORT-TERM EFFECTS OF MOBILIZATION-WITH-MOVEMENT (MWM AND AUTO-MWM APPLICATION IN RECREATIONAL RUNNERS WITH ILIOTIBIAL BAND SYNDROME

    Directory of Open Access Journals (Sweden)

    Konstantinos Zemadanis

    2017-12-01

    Full Text Available Background: It is well known that Iliotibial band syndrome (ITBS is the most frequent overuse injury in recreational runners. Given the fact that there are no clear guidelines on the optimal conservative treatment approach regarding ITBS rehabilitation, manual therapy effect by a functional joint mobilization is still unknown. The purpose of the study was to investigate whether implementation of mobilization-with-movement (MWM and auto-mobilization had a significant short-term improvement in pain and functionality of recreational runners with ITBS. Methods: Participants: thirty ITBS patients, were randomly assigned into two groups. Design and Settings: One group pre-test /post-test with the control group. Interventions: Runners on the treatment group followed an MWM protocol of six sessions with an additive program of auto-MWM, while the control group received a SHAM form of MWM. Outcome measurements: Pain and functionality were measured at baseline and post-treatment, via Numeric Pain Rating scale and Lower Extremity Functional Scale respectively. Mixed-ANOVA test detected possible differences among treatment phases and between groups, but also interactions among factors. Result: The present findings revealed significant interactions between factors and significant main effects of each TIME and GROUP factors on pain and functionality. MWM-treatment group showed significant improvement in post-intervention NPRT and LEFS scores, compared to baseline scores (p.001. Differences between groups were significant in post-treatment scores (p<.001. Conclusion: Our findings suggest that MWM and auto-MWM are a significant treatment approach, improving pain and functionality in recreational runners suffering from ITBS.

  10. Pareto-optimal multi-objective dimensionality reduction deep auto-encoder for mammography classification.

    Science.gov (United States)

    Taghanaki, Saeid Asgari; Kawahara, Jeremy; Miles, Brandon; Hamarneh, Ghassan

    2017-07-01

    Feature reduction is an essential stage in computer aided breast cancer diagnosis systems. Multilayer neural networks can be trained to extract relevant features by encoding high-dimensional data into low-dimensional codes. Optimizing traditional auto-encoders works well only if the initial weights are close to a proper solution. They are also trained to only reduce the mean squared reconstruction error (MRE) between the encoder inputs and the decoder outputs, but do not address the classification error. The goal of the current work is to test the hypothesis that extending traditional auto-encoders (which only minimize reconstruction error) to multi-objective optimization for finding Pareto-optimal solutions provides more discriminative features that will improve classification performance when compared to single-objective and other multi-objective approaches (i.e. scalarized and sequential). In this paper, we introduce a novel multi-objective optimization of deep auto-encoder networks, in which the auto-encoder optimizes two objectives: MRE and mean classification error (MCE) for Pareto-optimal solutions, rather than just MRE. These two objectives are optimized simultaneously by a non-dominated sorting genetic algorithm. We tested our method on 949 X-ray mammograms categorized into 12 classes. The results show that the features identified by the proposed algorithm allow a classification accuracy of up to 98.45%, demonstrating favourable accuracy over the results of state-of-the-art methods reported in the literature. We conclude that adding the classification objective to the traditional auto-encoder objective and optimizing for finding Pareto-optimal solutions, using evolutionary multi-objective optimization, results in producing more discriminative features. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. PREVALENCE OF CARDIO-VASCULAR DISEASE (CVD RISK FACTORS AMONG AUTO-RICKSHAW DRIVERS

    Directory of Open Access Journals (Sweden)

    Shailendra Chaudhary

    2011-06-01

    Full Text Available Research question: What is the prevalence of some cardio-vascular disease (CVD risk factors among auto-rickshaw drivers (ARDs working in Nagpur city of India? Methods: This cross-sectional study was conducted from June 2007 to December 2008 at the auto-rickshaw stand of Nagpur railway station. Out of total 6000 auto-rickshaw drivers (ARDs of Nagpur city, 296 were studied. Results: Mean age of ARDs was 41.70±9.05 years. Their mean length of occupation was 17 years and average daily working was 11½ hours. 40.20% subjects had habit of tobacco chewing; while 35.14% were smokers and 34.12% were alcohol consumers. Only 16.89% subjects were engaged in regular physical exercise. 27.36% subjects had ‘moderate’ or ‘severe’ self reported stress. Mean weight of these auto-rickshaw drivers was 58.59±9.25 kg; while their mean body mass index (BMI was 21.95±3.48 kg/m2. 14.86% subjects were overweight and another 3.38% had obesity. 37.16% subjects had pre-hypertension; while 104 (35.14% subjects had hypertension. 4.73% of the ARDs also had a family history of hypertension. Conclusions: As the prevalence of various CVD risk factors is high; there is an urgent need of regular health check-ups and appropriate preventive and promotive interventions among these auto-rickshaw drivers.

  12. Epinephrine Auto-Injector Versus Drawn Up Epinephrine for Anaphylaxis Management: A Scoping Review.

    Science.gov (United States)

    Chime, Nnenna O; Riese, Victoria G; Scherzer, Daniel J; Perretta, Julianne S; McNamara, LeAnn; Rosen, Michael A; Hunt, Elizabeth A

    2017-08-01

    Anaphylaxis is a life-threatening event. Most clinical symptoms of anaphylaxis can be reversed by prompt intramuscular administration of epinephrine using an auto-injector or epinephrine drawn up in a syringe and delays and errors may be fatal. The aim of this scoping review is to identify and compare errors associated with use of epinephrine drawn up in a syringe versus epinephrine auto-injectors in order to assist hospitals as they choose which approach minimizes risk of adverse events for their patients. PubMed, Embase, CINAHL, Web of Science, and the Cochrane Library were searched using terms agreed to a priori. We reviewed human and simulation studies reporting errors associated with the use of epinephrine in anaphylaxis. There were multiple screening stages with evolving feedback. Each study was independently assessed by two reviewers for eligibility. Data were extracted using an instrument modeled from the Zaza et al instrument and grouped into themes. Three main themes were noted: 1) ergonomics, 2) dosing errors, and 3) errors due to route of administration. Significant knowledge gaps in the operation of epinephrine auto-injectors among healthcare providers, patients, and caregivers were identified. For epinephrine in a syringe, there were more frequent reports of incorrect dosing and erroneous IV administration with associated adverse cardiac events. For the epinephrine auto-injector, unintentional administration to the digit was an error reported on multiple occasions. This scoping review highlights knowledge gaps and a diverse set of errors regardless of the approach to epinephrine preparation during management of anaphylaxis. There are more potentially life-threatening errors reported for epinephrine drawn up in a syringe than with the auto-injectors. The impact of these knowledge gaps and potentially fatal errors on patient outcomes, cost, and quality of care is worthy of further investigation.

  13. Auto Code Generation for Simulink-Based Attitude Determination Control System

    Science.gov (United States)

    MolinaFraticelli, Jose Carlos

    2012-01-01

    This paper details the work done to auto generate C code from a Simulink-Based Attitude Determination Control System (ADCS) to be used in target platforms. NASA Marshall Engineers have developed an ADCS Simulink simulation to be used as a component for the flight software of a satellite. This generated code can be used for carrying out Hardware in the loop testing of components for a satellite in a convenient manner with easily tunable parameters. Due to the nature of the embedded hardware components such as microcontrollers, this simulation code cannot be used directly, as it is, on the target platform and must first be converted into C code; this process is known as auto code generation. In order to generate C code from this simulation; it must be modified to follow specific standards set in place by the auto code generation process. Some of these modifications include changing certain simulation models into their atomic representations which can bring new complications into the simulation. The execution order of these models can change based on these modifications. Great care must be taken in order to maintain a working simulation that can also be used for auto code generation. After modifying the ADCS simulation for the auto code generation process, it is shown that the difference between the output data of the former and that of the latter is between acceptable bounds. Thus, it can be said that the process is a success since all the output requirements are met. Based on these results, it can be argued that this generated C code can be effectively used by any desired platform as long as it follows the specific memory requirements established in the Simulink Model.

  14. Increased glycosylation efficiency of recombinant proteins in Escherichia coli by auto-induction.

    Science.gov (United States)

    Ding, Ning; Yang, Chunguang; Sun, Shenxia; Han, Lichi; Ruan, Yao; Guo, Longhua; Hu, Xuejun; Zhang, Jianing

    2017-03-25

    Escherichia coli cells have been considered as promising hosts for producing N-glycosylated proteins since the successful production of N-glycosylated protein in E. coli with the pgl (N-linked protein glycosylation) locus from Campylobacter jejuni. However, one hurdle in producing N-glycosylated proteins in large scale using E. coli is inefficient glycan glycosylation. In this study, we developed a strategy for the production of N-glycosylated proteins with high efficiency via an optimized auto-induction method. The 10th human fibronectin type III domain (FN3) was engineered with native glycosylation sequon DFNRSK and optimized DQNAT sequon in C-terminus with flexible linker as acceptor protein models. The resulting glycosylation efficiencies were confirmed by Western blots with anti-FLAG M1 antibody. Increased efficiency of glycosylation was obtained by changing the conventional IPTG induction to auto-induction method, which increased the glycosylation efficiencies from 60% and 75% up to 90% and 100% respectively. Moreover, in the condition of inserting the glycosylation sequon in the loop of FN3 (the acceptor sequon with local structural conformation), the glycosylation efficiency was increased from 35% to 80% by our optimized auto-induction procedures. To justify the potential for general application of the optimized auto-induction method, the reconstituted lsg locus from Haemophilus influenzae and PglB from C. jejuni were utilized, and this led to 100% glycosylation efficiency. Our studies provided quantitative evidence that the optimized auto-induction method will facilitate the large-scale production of pure exogenous N-glycosylation proteins in E. coli cells. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. [PSYCHOTHERAPEUTIC INTERVENTIONS IN PATIENTS WITH AUTO-AGGRESSIVE BEHAVIOR DURING THE FIRST PSYCHOTIC EPISODE].

    Science.gov (United States)

    Mudrenko, I; Potapov, A; Sotnikov, D; Kolenko, O; Kmyta, A

    2017-09-01

    In this article the formation of psychopathological predictors auto-aggressive behavior in patients with a first psychotic episode were identified, which became "targets" in the framework of a comprehensive emergency suicide assistance to conduct the crisis psychotherapy. The work was done on the basis of the Sumy regional psychoneurologic dispensary, where 100 patients with a first psychotic episode were examined: 52 of them (core group) had suicidal symptoms and 48 (control group) had not. According to the test results of severity of auto-aggressive predictors (pre-suicidal syndrome) to clinicopsychopathological predictors of auto-aggressive behavior include: the narrowing of the cognitive function (p≤0,001), the avoidance of interpersonal contact (r≤0,001), the presence of affective (p≤0,001) and vegetative (p≤0,01) violations, the autoaggression of moderate severity (p≤0,001) and impulsivity (p≤0,001). Patients of the core group with the auto-aggressive behavior (n=58) completed a course of a crisis psychotherapy comprising the stages of crisis support, crisis intervention and increase the adaptation layer. After a psychotherapy course levels of aggression (6,45±0,41), auto-aggression (of 9,68±0,67), disorders in the affective sphere (18,58±0,66) and impulsivity (of 4,23±0,30) decreased, which was manifested in increasing tolerance to emotional stress factors, control over their emotions and reduce their affective valence (p≤0,001). The expansion of interpersonal interaction, the increase of patients social activity, the blood relationships establishment (of 9,23±0,40) was observed.

  16. AutoLab: a robotics solution for flexible laboratory automation

    Science.gov (United States)

    Ahmed, Nizam; Sowmya, Arcot

    1994-10-01

    This paper describes a proposal to develop a flexible automation system for sample preparation and analysis in a chemistry laboratory without human assistance. The key to such automation is a robot arm, centrally placed with respect to a series of work stations containing balances, mixers, dispensers, centrifuges and analytical instruments. Object handling at each station and sample movement from one station to another is performed by the robot arm according to user-programmed procedures. The research emphasizes the analysis and modular decomposition of chemistry procedures, modeling the procedures in a computer system and integrating this model with robot arm and other instrumentation hardware involved in a complete automation of a chemistry laboratory.

  17. Contactin-1 and Neurofascin-155/-186 Are Not Targets of Auto-Antibodies in Multifocal Motor Neuropathy.

    Directory of Open Access Journals (Sweden)

    Kathrin Doppler

    Full Text Available Multifocal motor neuropathy is an immune mediated disease presenting with multifocal muscle weakness and conduction block. IgM auto-antibodies against the ganglioside GM1 are detectable in about 50% of the patients. Auto-antibodies against the paranodal proteins contactin-1 and neurofascin-155 and the nodal protein neurofascin-186 have been detected in subgroups of patients with chronic inflammatory demyelinating polyneuropathy. Recently, auto-antibodies against neurofascin-186 and gliomedin were described in more than 60% of patients with multifocal motor neuropathy. In the current study, we aimed to validate this finding, using a combination of different assays for auto-antibody detection. In addition we intended to detect further auto-antibodies against paranodal proteins, specifically contactin-1 and neurofascin-155 in multifocal motor neuropathy patients' sera. We analyzed sera of 33 patients with well-characterized multifocal motor neuropathy for IgM or IgG anti-contactin-1, anti-neurofascin-155 or -186 antibodies using enzyme-linked immunosorbent assay, binding assays with transfected human embryonic kidney 293 cells and murine teased fibers. We did not detect any IgM or IgG auto-antibodies against contactin-1, neurofascin-155 or -186 in any of our multifocal motor neuropathy patients. We conclude that auto-antibodies against contactin-1, neurofascin-155 and -186 do not play a relevant role in the pathogenesis in this cohort with multifocal motor neuropathy.

  18. Estimates of Average Glandular Dose with Auto-modes of X-ray Exposures in Digital Breast Tomosynthesis

    Directory of Open Access Journals (Sweden)

    Izdihar Kamal

    2015-05-01

    Full Text Available Objectives: The aim of this research was to examine the average glandular dose (AGD of radiation among different breast compositions of glandular and adipose tissue with auto-modes of exposure factor selection in digital breast tomosynthesis. Methods: This experimental study was carried out in the National Cancer Society, Kuala Lumpur, Malaysia, between February 2012 and February 2013 using a tomosynthesis digital mammography X-ray machine. The entrance surface air kerma and the half-value layer were determined using a 100H thermoluminescent dosimeter on 50% glandular and 50% adipose tissue (50/50 and 20% glandular and 80% adipose tissue (20/80 commercially available breast phantoms (Computerized Imaging Reference Systems, Inc., Norfolk, Virginia, USA with auto-time, auto-filter and auto-kilovolt modes. Results: The lowest AGD for the 20/80 phantom with auto-time was 2.28 milliGray (mGy for two dimension (2D and 2.48 mGy for three dimensional (3D images. The lowest AGD for the 50/50 phantom with auto-time was 0.97 mGy for 2D and 1.0 mGy for 3D. Conclusion: The AGD values for both phantoms were lower against a high kilovolt peak and the use of auto-filter mode was more practical for quick acquisition while limiting the probability of operator error.

  19. Phenotypic modulation of auto-reactive cells by insertion of tolerogenic molecules via MSC-derived exosomes.

    Science.gov (United States)

    Mokarizadeh, Aram; Delirezh, Nowruz; Morshedi, Ahhmad; Mosayebi, Ghasem; Farshid, Amir-Abbas; Dalir-Naghadeh, Bahram

    2012-01-01

    Auto-reactive cells-mediated immune responses are responsible for the current tissue damages during autoimmunity. Accordingly, functional modulation of auto-reactive cells has been a pivotal aim in many of recent studies. In the current study, we investigated the possibility for insertion of regulatory molecules onto auto-reactive cells through exosomal nano-shuttles as a novel approach for phenotype modification of auto-reactive cells. The exosomes were isolated from supernatant of mesenchymal stem cells culture. Resultant exosomes co-cultured with lymphocytes were harvested from established EAE mice in the presence of antigenic MOG35-55 peptide. After 24 hr, insertion of exosomal tolerogenic molecules (PD-L1, TGF-β, galectin-1) onto auto-reactive cells were explored through flow cytometry. The potency of exosomal inserted membrane molecules to modulate phenotype of auto-reactive lymphocytes was assessed upon ELISA test for their-derived cytokines IFN-γ and IL-17. Incorporation of exosomal molecules into lymohocytes' membrane was confirmed by flow cytometric analyses for surface levels of mentioned molecules. Additionally, the decreased secretion of IFN-γ and IL-17 were detected in exosome pre-treated lymphocytes upon stimulation with MOG peptide. Mesenchymal stem cells -derived exosomes showed to be efficient organelles for insertion of bioactive tolerogenic molecules onto auto-reactive cells and modulation of their phenotypes.

  20. Factors affecting the development of atrial fibrillation and atrial flutter (AF/AFL) following autologous hematopoietic SCT (auto-HSCT).

    Science.gov (United States)

    Steuter, J A; Villanueva, M L H; Loberiza, F R; Armitage, J O; Bociek, R G; Ganti, A K; Tarantolo, S R; Vose, J M; Easley, A; Bierman, P J

    2013-07-01

    The use of autologous hematopoietic SCT (auto-HSCT) has expanded to include older patients. Increasing age is a well-appreciated risk factor for the development of atrial fibrillation and/or atrial flutter (AF/AFL) in the general population. As more elderly patients undergo auto-HSCT, the risk of developing AF/AFL post transplant may also increase. However, few data evaluating other risk factors for the development of AF/AFL following auto-HSCT exist. Therefore, we performed a retrospective study to determine the incidence of AF/AFL following auto-HSCT and to determine the risk factors associated with the development of AF/AFL. Patients who developed AF/AFL were compared with a group of patients who received auto-HSCT within the same time period (April 1999 to May 2005) and were within 5 years of age. Of the 516 patients who underwent auto-HSCT at the University of Nebraska Medical Center 44 (8.5%) developed AF/AFL at a median time of 4 days (range, days 1-9) following auto-HSCT. In multivariate analysis, risk factors for developing AF/AFL were older age, odds ratio and 95% CI of 1.14 (1.07-1.21), elevated serum creatinine level, 2.69 (1.00-7.22), history of previous arrhythmia, 9.33 (3.01-28.99), and history of previous mediastinal irradiation, 11.12 (1.33-92.96).

  1. Auto-eficácia para atividades ocupacionais e interesses profissionais em estudantes do ensino médio

    Directory of Open Access Journals (Sweden)

    Maiana Farias Oliveira Nunes

    Full Text Available A auto-eficácia para as atividades ocupacionais e os interesses profissionais descrevem, respectivamente, atividades que os jovens possuem confiança de que podem desempenhar e ações que gostariam de executar. Os objetivos deste artigo foram analisar diferenças de média na auto-eficácia e suas fontes e nos interesses em função das variáveis gênero, tipo de escola e série escolar. Participaram 333 alunos do ensino médio, com média de idade de 15,9 anos, sendo 182 mulheres, que responderam a EAAOc e o SDS, que avaliam auto-eficácia e interesses. A auto-eficácia, classificada de acordo com os tipos de Holland, apresentou padrão IRSAEC, e os interesses, ESIACR. Houve diferenças significativas em função do gênero para os interesses, a auto-eficácia e suas fontes. Não houve diferenças significativas para a auto-eficácia pela série escolar ou tipo de escola. Algumas fontes de auto-eficácia apresentaram diferenças pelo tipo de escola e série escolar, tendo o mesmo ocorrido com alguns perfis de interesse.

  2. Program system HARM designed for analyzing the frequencies of vibroacoustic signals

    Energy Technology Data Exchange (ETDEWEB)

    Barszczewski, L.

    1987-06-01

    The described program system HARM has resulted from development works in the field of measuring signal analysis at the Institute of Industrial Automation of the Warsaw Technical College. Equipment is based on a minicomputer MERA-60/30 with the CAMAC cassette connected for measuring data collection. The system is able to carry out both single-channel and two-channel analyses. The following statistical estimates can be performed: auto and cross correlations, auto and cross power spectra, transfer functions.

  3. Promoção do auto-conceito e auto-estima na pessoa com doença mental, aplicando técnicas expressivas

    OpenAIRE

    Gomes, Elsa Sofia Carvalho

    2012-01-01

    Mestrado, Enfermagemde Saúde Mental e Psiquiátrica, 2012, Escola Superior de Enfermagem de Lisboa A minha finalidade ao longo do curso foi desenvolver competências do Enfermeiro Especialista em Saúde Mental e Psiquiatria e Psiquiatria. Neste estágio o desenvolvimento dessas competências centrou-se nas intervenções psicoterapêuticas, com recurso a técnicas de terapias expressivas, em utentes com alteração do autoconceito e baixa de auto-estima. Nesta perspectiva procurei também compreender ...

  4. Clinical assessment of auto-positive end-expiratory pressure by diaphragmatic electrical activity during pressure support and neurally adjusted ventilatory assist.

    Science.gov (United States)

    Bellani, Giacomo; Coppadoro, Andrea; Patroniti, Nicolò; Turella, Marta; Arrigoni Marocco, Stefano; Grasselli, Giacomo; Mauri, Tommaso; Pesenti, Antonio

    2014-09-01

    Auto-positive end-expiratory pressure (auto-PEEP) may substantially increase the inspiratory effort during assisted mechanical ventilation. Purpose of this study was to assess whether the electrical activity of the diaphragm (EAdi) signal can be reliably used to estimate auto-PEEP in patients undergoing pressure support ventilation and neurally adjusted ventilatory assist (NAVA) and whether NAVA was beneficial in comparison with pressure support ventilation in patients affected by auto-PEEP. In 10 patients with a clinical suspicion of auto-PEEP, the authors simultaneously recorded EAdi, airway, esophageal pressure, and flow during pressure support and NAVA, whereas external PEEP was increased from 2 to 14 cm H2O. Tracings were analyzed to measure apparent "dynamic" auto-PEEP (decrease in esophageal pressure to generate inspiratory flow), auto-EAdi (EAdi value at the onset of inspiratory flow), and IDEAdi (inspiratory delay between the onset of EAdi and the inspiratory flow). The pressure necessary to overcome auto-PEEP, auto-EAdi, and IDEAdi was significantly lower in NAVA as compared with pressure support ventilation, decreased with increase in external PEEP, although the effect of external PEEP was less pronounced in NAVA. Both auto-EAdi and IDEAdi were tightly correlated with auto-PEEP (r = 0.94 and r = 0.75, respectively). In the presence of auto-PEEP at lower external PEEP levels, NAVA was characterized by a characteristic shape of the airway pressure. In patients with auto-PEEP, NAVA, compared with pressure support ventilation, led to a decrease in the pressure necessary to overcome auto-PEEP, which could be reliably monitored by the electrical activity of the diaphragm before inspiratory flow onset (auto-EAdi).

  5. Long-term outcome of patients with multiple [corrected] myeloma-related advanced renal failure following auto-SCT.

    Science.gov (United States)

    Glavey, S V; Gertz, M A; Dispenzieri, A; Kumar, S; Buadi, F; Lacy, M; Hayman, S R; Kapoor, P; Dingli, D; McCurdy, A; Hogan, W J; Gastineau, D A; Leung, N

    2013-11-01

    Renal failure commonly complicates multiple myeloma (MM) and is associated with reduced survival. It is not clear whether auto-SCT results in improved renal function or attainment of independence from dialysis in patients with advanced renal impairment due to MM. We conducted a retrospective cohort study of all patients who underwent auto-SCT for MM complicated by advanced renal failure at our institution over a 10-year period (2000-2010). We aimed to assess the association between auto-SCT and renal outcome in patients with serum creatinine (SCr) over 3 mg/dL, attributable to MM, including those who were dialysis dependent. Thirty patients (2.8% of all auto-SCT patients) met inclusion criteria. Fourteen of 15 patients who were dialysis dependent before auto-SCT remained dialysis dependent in the long term despite hematological response (HR). Of the remaining 15 patients with SCr >3 mg/dL, an improvement in glomerular filtration rate (GFR) from 15 to 19.4 mL/min/1.73 m(2) was noted post auto-SCT (P=0.035); however, neither HR post auto-SCT or pre-existing renal function were independently associated with renal outcome. Auto-SCT was not associated with independence from dialysis in patients with renal failure due to MM at our institution. Although auto-SCT was associated with an improvement in GFR in patients with SCr >3 mg/dL, this improvement was not related to HR.

  6. How To Refinish Wood Siding With Latex Paints

    Science.gov (United States)

    E. A. Mraz

    1976-01-01

    Every homeowner with painted wood siding and trim at some time faces the job of repainting. In this note a simple test is described to determine whether an old surface will form a satisfactory bond with latex paints, and suggestions are given on preparing the surface to achieve a satisfactory bond.

  7. Capturing the Sun: A Roadmap for Navigating Data-Access Challenges and Auto-Populating Solar Home Sales Listings

    Energy Technology Data Exchange (ETDEWEB)

    Stukel, Laura [Elevate Energy, Chicago, IL (United States); Hoen, Ben [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Adomatis, Sandra [Adomatis Appraisal Services, Punta Gorda, FL (United States); Foley, Craig [Sustainable Real Estate Consulting Services, Somerville, MA (United States); Parsons, Laura [Center for Sustainable Energy, San Diego, CA (United States); James, Mark [Vermont Law School, South Royalton, VT (United States). Inst. for Energy and Environment; Mastor, Roxana-Andreea [Vermont Law School, South Royalton, VT (United States). Inst. for Energy and Environment; Wedewer, Lindsey [Colorado Energy Office, Denver, CO (United States)

    2017-04-13

    Capturing the Sun: A Roadmap for Navigating Data-Access Challenges and Auto-Populating Solar Home Sales Listings supports a vision of solar photovoltaic (PV) advocates and real estate advocates evolving together to make information about solar homes more accessible to home buyers and sellers and to simplify the process when these homes are resold. The Roadmap is based on a concept in the real estate industry known as automatic population of fields. Auto-population (also called auto-pop in the industry) is the technology that allows data aggregated by an outside industry to be matched automatically with home sale listings in a multiple listing service (MLS).

  8. Efeitos da idade, sexo e nível sócio-cultural no auto-conceito

    OpenAIRE

    Peixoto, Francisco José Brito; Mata, Maria de Lourdes Estorninho Neves

    1993-01-01

    O presente trabalho teve por objectivo a análise dos efeitos das variáveis idade, sexo e nível sócio- -cultural no auto-conceito e na auto-estima, de sujeitos pré-adolescentes. A 586 sujeitos a frequentarem o terceiro, quarto, quinto ou sexto ano de escolaridade, foi administrada a escala de auto-conceito de Susan Harter. Os resultados mostram uma influência da variável idade para todos os domínios considerados e das variáveis sexo e nível sócio-cultural para alguma...

  9. Hand-Assisted Laparoscopic Nephrectomy and Auto-Transplantation for a Hilar Renal Artery Aneurysm: A Case Report.

    Science.gov (United States)

    Kim, Min Jung; Lee, Kyo Won; Park, Jae Berm; Kim, Sung Joo

    2017-06-01

    A 52-year-old man was admitted with an incidentally detected right renal artery aneurysm (RAA). Computed tomographic angiography with three-dimensional reconstruction revealed that the aneurysm was 2.2 cm in diameter and located at the renal hilum. We performed hand-assisted laparoscopic nephrectomy with ex vivo repair of the RAA and auto-transplantation with minimal elongation of Gibson incision. The operation and postoperative course were uneventful. At last follow-up, the patient was alive with a well-functioning auto-transplant. Hand-assisted laparoscopic nephrectomy and auto-transplantation is a useful treatment option for hilar RAA.

  10. Aplicando el auto-habla con tenistas adultos: la familiarización con la técnica

    OpenAIRE

    Latinjak, Alexander T.; Miquel Torregrosa; Jordi Renom

    2011-01-01

    El objetivo de este trabajo ha sido estudiar el proceso de familiarización de un deportista con la técnica del auto-habla. Para ello, 14 tenistas adultos (edad media = 39,36, DT = 6,18) han aplicado un auto-habla instruccional y auto determinado durante varias repeticiones de una tarea de tenis. Hemos medido la dificultad percibida y la efectividad percibida de la técni­ca, además del acierto, la satisfacción con el rendimiento y concentración percibida. Los análisis de la varianza con medida...

  11. Sub-cellular trafficking of phytochemicals explored using auto-fluorescent compounds in maize cells

    Directory of Open Access Journals (Sweden)

    Grotewold Erich

    2003-12-01

    Full Text Available Abstract Background Little is known regarding the trafficking mechanisms of small molecules within plant cells. It remains to be established whether phytochemicals are transported by pathways similar to those used by proteins, or whether the expansion of metabolic pathways in plants was associated with the evolution of novel trafficking pathways. In this paper, we exploited the induction of green and yellow auto-fluorescent compounds in maize cultured cells by the P1 transcription factor to investigate their targeting to the cell wall and vacuole, respectively. Results We investigated the accumulation and sub-cellular localization of the green and yellow auto-fluorescent compounds in maize BMS cells expressing the P1 transcription factor from an estradiol inducible promoter. We established that the yellow fluorescent compounds accumulate inside the vacuole in YFBs that resemble AVIs. The green fluorescent compounds accumulate initially in the cytoplasm in large spherical GFBs. Cells accumulating GFBs also contain electron-dense structures that accumulate initially in the ER and which later appear to fuse with the plasma membrane. Structures resembling the GFBs were also observed in the periplasmic space of plasmolized cells. Ultimately, the green fluorescence accumulates in the cell wall, in a process that is insensitive to the Golgi-disturbing agents BFA and monensin. Conclusions Our results suggest the presence of at least two distinct trafficking pathways, one to the cell wall and the other to the vacuole, for different auto-fluorescent compounds induced by the same transcription factor in maize BMS cells. These compartments represent two of the major sites of accumulation of phenolic compounds characteristic of maize cells. The secretion of the green auto-fluorescent compounds occurs by a pathway that does not involve the TGN, suggesting that it is different from the secretion of most proteins, polysaccharides or epicuticular waxes. The

  12. Autogas at Equip'Auto 2001: a very calm vintage; Le GPL a Equip'Auto 2001, un cru bien calme

    Energy Technology Data Exchange (ETDEWEB)

    Valcano, N.

    2001-09-01

    Autogas equipment manufacturers and importers, as well as the other actors in this field will be present in a mitigated atmosphere at the Equip'Auto 2001 Trade Show, at Paris-Nord Villepinte from 16 to 21 October. The market is at slow pace after new regulatory changes and this leads importers and installers/fitters to act in a carefulness way, as the retrofit operation in progress across the country (the fitting of the R67-01 type safety relief valve) amounts today to a large share in installers' activity. Thus, no more than a dozen of booths will show autogas components and technologies. Nevertheless, some brand new products will be exhibited. At the end of August, foreign exhibitors listed were Sahinler Metal (Turkey) and Brecav (Italy). But some brands will be found on importers booths. Cora Auto distributes Tartarini's Etagas system, as does on its side 'la Carburation Gaz'. OMVL and now Landi will be found at France GPL Carburation's. Cofraca, the French arm of Necam-Koltec, will be present, as well as some installers groupings, dispensers manufacturers and Autogas distributors. (authors)

  13. PID controller auto-tuning based on process step response and damping optimum criterion.

    Science.gov (United States)

    Pavković, Danijel; Polak, Siniša; Zorc, Davor

    2014-01-01

    This paper presents a novel method of PID controller tuning suitable for higher-order aperiodic processes and aimed at step response-based auto-tuning applications. The PID controller tuning is based on the identification of so-called n-th order lag (PTn) process model and application of damping optimum criterion, thus facilitating straightforward algebraic rules for the adjustment of both the closed-loop response speed and damping. The PTn model identification is based on the process step response, wherein the PTn model parameters are evaluated in a novel manner from the process step response equivalent dead-time and lag time constant. The effectiveness of the proposed PTn model parameter estimation procedure and the related damping optimum-based PID controller auto-tuning have been verified by means of extensive computer simulations. © 2013 ISA. Published by Elsevier Ltd. All rights reserved.

  14. User productivity as a function of AutoCAD interface design.

    Science.gov (United States)

    Mitta, D A; Flores, P L

    1995-12-01

    Increased operator productivity is a desired outcome of user-CAD interaction scenarios. Two objectives of this research were to (1) define a measure of operator productivity and (2) empirically investigate the potential effects of CAD interface design on operator productivity, where productivity is defined as the percentage of a drawing session correctly completed per unit time. Here, AutoCAD provides the CAD environment of interest. Productivity with respect to two AutoCAD interface designs (menu, template) and three task types (draw, dimension, display) was investigated. Analysis of user productivity data revealed significantly higher productivity under the menu interface condition than under the template interface condition. A significant effect of task type was also discovered, where user productivity under display tasks was higher than productivity under the draw and dimension tasks. Implications of these results are presented.

  15. A Digital Auto-Zeroing Circuit to Reduce Offset in Sub-Threshold Sense Amplifiers

    Directory of Open Access Journals (Sweden)

    Benton H. Calhoun

    2013-05-01

    Full Text Available Device variability in modern processes has become a major concern in SRAM design leading to degradation of both performance and yield. Variation induced offset in the sense amplifiers requires a larger bitline differential, which slows down SRAM access times and causes increased power consumption. The effect aggravated in the sub-threshold region. In this paper, we propose a circuit that reduces the sense amp offset using an auto-zeroing scheme with automatic temperature, voltage, and aging tracking. The circuit enables flexible tuning of the offset voltage. Measurements taken from a 45 nm test chip show the circuit is able to limit the offset to 20 mV. A 16kB SRAM is designed using the auto-zeroing circuit for the sense amps. The reduction in the total read energy and delay is reported for various configurations of the memory.

  16. Auto-ignition generated combustion. Pt. 2. Thermodynamic fundamentals; Verbrennungssteuerung durch Selbstzuendung. T. 2. Experimentelle Analyse

    Energy Technology Data Exchange (ETDEWEB)

    Guibert, P. [Paris-6 Univ. (France). Lab. de Mecanique Physique; Morin, C. [Paris-6 Univ. (France); Mokhtari, S.

    2004-02-01

    The combustion initiation by auto-ignition demonstrates benefits in NO{sub x} reduction and in process stability for both spark-ignited and compression ignited engines. Based on the better thermodynamic particularities of the auto-ignition, which have been presented in the first part, the characteristics of this process are demonstrated in the second part by experimental analysis. For comparison with similar studies, the analyses have been carried out in base of a two stroke loop scavenged spark-ignition single cylinder engine. (orig.) [German] Die Steuerung der Verbrennung durch Selbstzuendung zeigt Vorteile bezueglich Senkung der NO{sub x}-Emission und Prozessstabilitaet, sowohl bei Otto- als auch bei Dieselmotoren. Auf Grundlage der thermodynamischen Besonderheiten der Selbstzuendvorgaenge, die im ersten Teil praesentiert wurden, erfolgt im zweiten Teil eine experimentelle Betrachtung der Prozesscharakteristika. Zur Vergleichbarkeit mit aehnlichen Untersuchungen wird die experimentelle Analyse auf Basis eines Zweitakt-Einzylinder-Ottomotors mit Umkehrspuelung durchgefuehrt. (orig.)

  17. Auto white balance method using a pigmentation separation technique for human skin color

    Science.gov (United States)

    Tanaka, Satomi; Kakinuma, Akihiro; Kamijo, Naohiro; Takahashi, Hiroshi; Tsumura, Norimichi

    2017-02-01

    The human visual system maintains the perception of colors of an object across various light sources. Similarly, current digital cameras feature an auto white balance function, which estimates the illuminant color and corrects the color of a photograph as if the photograph was taken under a certain light source. The main subject in a photograph is often a person's face, which could be used to estimate the illuminant color. However, such estimation is adversely affected by differences in facial colors among individuals. The present paper proposes an auto white balance algorithm based on a pigmentation separation method that separates the human skin color image into the components of melanin, hemoglobin and shading. Pigment densities have a uniform property within the same race that can be calculated from the components of melanin and hemoglobin in the face. We, thus, propose a method that uses the subject's facial color in an image and is unaffected by individual differences in facial color among Japanese people.

  18. Antivital experience and auto-aggressive behavior in teenagers with “diffuse identity”2

    Directory of Open Access Journals (Sweden)

    G. S. Bannikov

    2013-04-01

    Full Text Available In order to identify the role of “diffuse identity” in the development of antivital experience and auto-aggressive behavior, we examined 60 adolescents (24 boys and 36 girls who sought for psychological or psychiatric aid in medical and psychological services in Moscow. The average age of the participants was 15,7 ± 6 years. We revealed two groups of adolescents (70% with moderate to severe degree of “diffuse identity”, who have unique inherent characteristics of identity conflict, structural features, and pattern of interpersonal relations construction. Alto-gether, these characteristics determine the leading pattern of behavior, way of antivital feelings and auto-agressive behavior formation, resources and capacities of adolescents in crisis. Psychological aid in crisis, considering these features and using them, allows one to create new and effective coping strategies that are specific to each group.

  19. A Solidão e o Auto-Conceito na Idade Adulta e Velhice

    OpenAIRE

    Ferreira, Sandy Lousada; Cunha, Marina (Orientadora)

    2009-01-01

    Neste estudo propomo-nos estudar as possíveis diferenças existentes entre a idade adulta e a velhice ao nível da solidão e do auto-conceito. Analisámos o papel de variáveis psicossociais específicas e de variáveis psicológicas, como a depressão, ansiedade, stresse e estilos de coping, sobre a solidão, bem como qual o conjunto de variáveis que melhor prediz a solidão. A solidão e o auto-conceito constituem constructos relevantes na vida do ser humano nas mais variadas formas,...

  20. EXCHANGE RATE VOLATILITY AND U.S. AUTO-INDUSTRY EXPORTS: A PANEL COINTEGRATION APPROACH

    Directory of Open Access Journals (Sweden)

    Veysel Avsar

    2013-10-01

    Full Text Available Intermediate goods are often neglected in the empirical studies of the impact of exchange rate volatility on bilateral trade flows. Using import unit values of 58 motor vehicle products and 193 auto-parts, which are classified by the 10-digit level of Harmonized Tariff Schedule (HTS, this study examines the impact of exchange rate volatility on the U.S. automotive industry exports and imports (both motor-vehicle products and auto-parts from 37 major trading partners for the period of 1996.01 to 2008.4 by using panel data cointegration techniques. We obtain substantial heterogeneity in terms of the impact of exchange rate volatility for final and intermediate goods. We also find support for the positive hypothesis that exchange rate volatility may lead to greater levels of trade.

  1. Auto and hetero-associative memory using a 2-D optical logic gate

    Science.gov (United States)

    Chao, Tien-Hsin (Inventor)

    1992-01-01

    An optical system for auto-associative and hetero-associative recall utilizing Hamming distance as the similarity measure between a binary input image vector V(sup k) and a binary image vector V(sup m) in a first memory array using an optical Exclusive-OR gate for multiplication of each of a plurality of different binary image vectors in memory by the input image vector. After integrating the light of each product V(sup k) x V(sup m), a shortest Hamming distance detection electronics module determines which product has the lowest light intensity and emits a signal that activates a light emitting diode to illuminate a corresponding image vector in a second memory array for display. That corresponding image vector is identical to the memory image vector V(sup m) in the first memory array for auto-associative recall or related to it, such as by name, for hetero-associative recall.

  2. Chemotaxis and auto-chemotaxis of self-propelling artificial droplet swimmers

    Science.gov (United States)

    Jin, Chenyu; Krueger, Carsten; Maass, Corinna

    Chemotaxis and auto-chemotaxis are key mechanisms in the dynamics of micro-organisms, e.g. in the acquisition of nutrients and in the communication between individuals, influencing the collective behavior. However, chemical signalling and the natural environment of biological swimmers are generally complex, making them hard to access analytically. Simple experimental systems showing similar features could provide vital insights. We present such a swimmer system, as well as controlled assays to study chemotactic effects quantitatively and reproducibly. In our experiments, we let auto-chemotactic droplet swimmers pass through bifurcating microfluidic channels and record anticorrelations between the branch choices of consecutive droplets. We present an analytical model based on balancing stochastic forces versus a diffusing chemical gradient matching the experimental data. supported by the DFG SPP 1726 ''Microswimmers'' and the MaxSynBio network.

  3. Novel Auto-Reclosing Blocking Method for Combined Overhead-Cable Lines in Power Networks

    Directory of Open Access Journals (Sweden)

    Ricardo Granizo Arrabé

    2016-11-01

    Full Text Available This paper presents a novel auto-reclosing blocking method for combined overhead-cable lines in power distribution networks that are solidly or impedance grounded, with distribution transformers in a delta connection in their high-voltage sides. The main contribution of this new technique is that it can detect whether a ground fault has been produced at the overhead line side or at the cable line side, thus improving the performance of the auto-reclosing functionality. This localization technique is based on the measurements and analysis of the argument differences between the load currents in the active conductors of the cable and the currents in the shields at the cable end where the transformers in delta connection are installed, including a wavelet analysis. This technique has been verified through computer simulations and experimental laboratory tests.

  4. Slow motion replay detection of tennis video based on color auto-correlogram

    Science.gov (United States)

    Zhang, Xiaoli; Zhi, Min

    2012-04-01

    In this paper, an effective slow motion replay detection method for tennis videos which contains logo transition is proposed. This method is based on the theory of color auto-correlogram and achieved by fowllowing steps: First,detect the candidate logo transition areas from the video frame sequence. Second, generate logo template. Then use color auto-correlogram for similarity matching between video frames and logo template in the candidate logo transition areas. Finally, select logo frames according to the matching results and locate the borders of slow motion accurately by using the brightness change during logo transition process. Experiment shows that, unlike previous approaches, this method has a great improvement in border locating accuracy rate, and can be used for other sports videos which have logo transition, too. In addition, as the algorithm only calculate the contents in the central area of the video frames, speed of the algorithm has been improved greatly.

  5. Robot Assisted Renal Auto Transplantation: A Case Based Discussion of Unique Anaesthetic Considerations

    Directory of Open Access Journals (Sweden)

    Praveen Gupta

    2015-02-01

    Full Text Available Laparoscopic renal autotransplantation has serious perturbations on the body's homeostasis due to its non physiological positioning, use of pneumoperitoneum, changing fluid strategy at different points of time and on-going steps to maintain optimal environment for the transplanted kidney. Generally speaking, the anaesthetic management of renal auto-transplantation by open technique is not very complex and the perioperative management can be categorized in the intermediate level of clinical skill requirement. Adding to the comfort of the anaesthesiologist is the fact that these patients are not in end stage renal disease state and does not manifest the comorbidities, multisystem involvement and technical complexities of long term renal dysfunction and renal replacement therapy. In our case report surgeons used the da Vinci surgical robotic system for laparoscopic transplantation of the kidney at a new site. In this article we discuss the anaesthetic challenges of robot assisted laparoscopic renal auto-transplantation along with a description of our index case.

  6. High density growth of T7 expression strains with auto-induction option

    Energy Technology Data Exchange (ETDEWEB)

    Studier, F. William (Stony Brook, NY)

    2010-07-20

    A bacterial growth medium for promoting auto-induction of transcription of cloned DNA in cultures of bacterial cells grown batchwise is disclosed. The transcription is under the control of a lac repressor. Also disclosed is a bacterial growth medium for improving the production of a selenomethionine-containing protein or polypeptide in a bacterial cell, the protein or polypeptide being produced by recombinant DNA techniques from a lac or T7lac promoter, the bacterial cell encoding a vitamin B12-dependent homocysteine methylase. Finally, disclosed is a bacterial growth medium for suppressing auto-induction of expression in cultures of bacterial cells grown batchwise, said transcription being under the control of lac repressor.

  7. AutoSync : Automatic duty-cycle control for synchronous low-power listening

    DEFF Research Database (Denmark)

    Hansen, Morten Tranberg; Kusy, Branislav; Jurdak, Raja

    2012-01-01

    Low power listening (LPL) has been widely adopted to save energy in wireless sensor networks. However, LPL is ineffective in adapting to dynamic networks with asymmetric traffic patterns, as it sets a network-wide check interval. As a result, nodes with low data traffic waste significant energy...... resources doing idle listening. This problem is particularly exacerbated in multi-radio networks where majority of data comes through the most reliable radio and the duty cycles of other radios could be reduced. We address this issue in AutoSync, a protocol that combines synchronous LPL with automatic...... experiments. Results show that AutoSync attains a substantial increase in the operational lifetime and mean power consumption over existing protocols in single radio networks and even more in dual radio networks....

  8. The Signal Detection and Control Circuit Design for Confocal Auto-Focus System

    Directory of Open Access Journals (Sweden)

    Yin Liu

    2016-01-01

    Full Text Available Based on the demands of Confocal Auto-Focus system, the implementation method of signal measurement circuit and control circuit is given. Using the high performance instrumental amplifier AD620BN, low noise precision FET Op amplifier AD795JRZ and ultralow offset voltage Op amplifier OP07EP, a signal measurement circuit used to converse the two differential light intensity signal to electric signal is designed. And a control circuit which takes MCU MSP430F149 as core processes the former signal and generate a control signal driving the platform for auto-focusing. The experimental results proved the feasibility and correctness of circuits. And the system meets the design requirement.

  9. Cavity-enhanced Faraday rotation measurement with auto-balanced photodetection.

    Science.gov (United States)

    Chang, Chia-Yu; Shy, Jow-Tsong

    2015-10-01

    Optical cavity enhancement for a tiny Faraday rotation is demonstrated with auto-balanced photodetection. This configuration is analyzed using the Jones matrix formalism. The resonant rotation signal is amplified, and thus, the angular sensitivity is improved. In the experiment, the air Faraday rotation is measured with an auto-balanced photoreceiver in single-pass and cavity geometries. The result shows that the measured Faraday rotation in the single-pass geometry is enhanced by a factor of 85 in the cavity geometry, and the sensitivity is improved to 7.54×10(-10)  rad Hz(-1/2), which agrees well with the Jones matrix analysis. With this verification, we propose an AC magnetic sensor whose magnetic sensitivity is expected to achieve 10  pT Hz(-1/2).

  10. Contours, 2ft Contour Information in AutoCAD & ArcInfo formats. AutoCAD contains cut line information. NAD83, Nevada State Plane, West Zone, US Foot. Broken into Township, Range, and Section Grids, Published in 2006, City of Carson City Government.

    Data.gov (United States)

    NSGIC Local Govt | GIS Inventory — Contours dataset current as of 2006. 2ft Contour Information in AutoCAD & ArcInfo formats. AutoCAD contains cut line information. NAD83, Nevada State Plane, West...

  11. DETERMINING TACTICAL OPERATIONAL PLANNING POLICIES FOR AN AUTO CARRIER – A CASE STUDY

    Directory of Open Access Journals (Sweden)

    A.J. Du Plessis

    2012-01-01

    Full Text Available

    ENGLISH ABSTRACT: This study was done to assist a local auto carrier company with tactical operational planning. The objective of the planning process is to maximise the number of vehicles delivered while being on time and adhering to staff and maintenance schedule constraints.

    We investigated the feasibility of allowing part of the fleet to roam the closed spatial network, as opposed to the traditional assignment of the complete fleet to fixed routes. We developed decision-making rules for roaming and fixed-to-route auto carriers, and evaluated the quality of these proposed rules, in combination with different fleet compositions, using discrete event simulation and four performance measures.

    We found that the auto carrier company should adopt a tactical operations policy where at least 50% of the fleet is allowed to roam, while roaming auto carriers pick vehicles to transport according to specific rules.

    AFRIKAANSE OPSOMMING: Hierdie studie is gedoen om ’n plaaslike motorvervoer-onderneming te help met taktiese bedryfsbeplanning. Die doelwit van die beplanningsproses is om die aantal voertuie wat betyds afgelewer word te maksimeer met inagneming van personeel- en instandhoudingbeperkings. Ons het die moontlikheid dat ’n deel van die vragmotorvloot swerwend in die geslote ruimtelike roete-network moet opereer, ondersoek. Dit is in teenstelling met die tradisionele vaste toedeling van vragmotors aan roetes. Besluitnemingreëls vir swerwende en vaste-roete vragmotors is ontwikkel, en die gehalte van die reëls is met diskrete simulasie en vier prestasiemaatstawwe evalueer.

    Ons het bevind dat die vervoeronderneming ’n bedryfsbeleid behoort te aanvaar wat toelaat dat ten minste 50% van die vloot swerf, terwyl hierdie swerwende vragmotors voertuie volgens spesifieke reëls by oplaaipunte moet kies.

  12. The influence of platinum washing-out time on its recovery from used auto catalytic converters

    Directory of Open Access Journals (Sweden)

    A. Fornalczyk

    2014-07-01

    Full Text Available The used catalytic converters contain small amounts of precious metals. Recovery of these metals is essential for environmental and economic reasons. This work presents a method of Platinum Group Metals (PGM recovery from auto catalytic converters in which they are washed out by a liquid metal. The magneto-hydro-dynamic pump was used to force circulation of liquid metal under the influence of electromagnetic fields The influence of process time on platinum recovery was also carried out.

  13. Auto-Gopher-II: an autonomous wireline rotary-hammer ultrasonic drill

    Science.gov (United States)

    Badescu, Mircea; Lee, Hyeong Jae; Sherrit, Stewart; Bao, Xiaoqi; Bar-Cohen, Yoseph; Jackson, Shannon; Chesin, Jacob; Zacny, Kris; Paulsen, Gale L.; Mellerowicz, Bolek; Kim, Daniel

    2017-04-01

    Developing technologies that would enable future NASA exploration missions to penetrate deeper into the subsurface of planetary bodies for sample collection is of great importance. Performing these tasks while using minimal mass/volume systems and with low energy consumption is another set of requirements imposed on such technologies. A deep drill, called Auto-Gopher II, is currently being developed as a joint effort between JPL's NDEAA laboratory and Honeybee Robotics Corp. The Auto-Gopher II is a wireline rotary-hammer drill that combines formation breaking by hammering using an ultrasonic actuator and cuttings removal by rotating a fluted auger bit. The hammering mechanism is based on the Ultrasonic/Sonic Drill/Corer (USDC) mechanism that has been developed as an adaptable tool for many drilling and coring applications. The USDC uses an intermediate free-flying mass to transform high frequency vibrations of a piezoelectric transducer horn tip into sonic hammering of the drill bit. The USDC concept was used in a previous task to develop an Ultrasonic/Sonic Ice Gopher and then integrated into a rotary hammer device to develop the Auto-Gopher-I. The lessons learned from these developments are being integrated into the development of the Auto- Gopher-II, an autonomous deep wireline drill with integrated cuttings and sample management and drive electronics. Subsystems of the wireline drill are being developed in parallel at JPL and Honeybee Robotics Ltd. This paper presents the development efforts of the piezoelectric actuator, cuttings removal and retention flutes and drive electronics.

  14. Améliorer la performance organisationnelle : Manuel d'auto-évaluation

    International Development Research Centre (IDRC) Digital Library (Canada)

    Avez-vous pris la mesure de la performance réelle de votre organisation ? Dans le cas contraire, en connaissez-vous la cause ? Ce manuel présente un modèle d'auto-évaluation organisationnelle novateur et opportunément éprouvé. Les instruments et les conseils proposés dans Améliorer la performance ...

  15. Experimental and theoretical analysis of auto-parametric stability of pendulum with viscous dampers

    Czech Academy of Sciences Publication Activity Database

    Pospíšil, Stanislav; Fischer, Cyril; Náprstek, Jiří

    2011-01-01

    Roč. 56, č. 4 (2011), s. 359-378 ISSN 0001-7043 R&D Projects: GA AV ČR(CZ) IAA200710805; GA ČR(CZ) IAA200710902; GA ČR(CZ) GA103/09/0094 Institutional research plan: CEZ:AV0Z20710524 Keywords : auto-parametric pendulum * variable damping * semi-trivial stability * limit cycles Subject RIV: JM - Building Engineering

  16. Efficiency and Cost Analysis of Cell Saver Auto Transfusion System in Total Knee Arthroplasty

    OpenAIRE

    Bilgili, Mustafa Gökhan; Erçin, Ersin; Peker, Gökhan; Kural, Cemal; Başaran, Serdar Hakan; Duramaz, Altuğ; Avkan, Cevdet

    2014-01-01

    Background: Blood loss and replacement is still a controversial issue in major orthopaedic surgery. Allogenic blood transfusion may cause legal problems and concerns regarding the transmission of transfusion-related diseases. Cellsaver Systems (CSS) were developed as an alternative to allogenic transfusion but CSS transfusion may cause coagulation, infection and haemodynamic instability. Aims: Our aim was to analyse the efficiency and cost analysis of a cell saver auto-transfusion system ...

  17. State of the art on hydrogen passive auto-catalytic recombiner (european union Parsoar project)

    Energy Technology Data Exchange (ETDEWEB)

    Arnould, F.; Bachellerie, E. [Technicatome, 13 - Aix en Provence (France); Auglaire, M. [Tractebel Energy Engineering, Brussels (Belgium); Boeck, B. de [Association Vincotte Nuclear, Brussels (Belgium); Braillard, O. [CEA Cadarache, 13 - Saint Paul lez Durance (France); Eckardt, B. [Siemens AG, Offenbach am Main (Germany); Ferroni, F. [Electrowatt Engineering Limited, Zurich (Switzerland); Moffett, R. [Atomic Energy Canada Limited, Pinawa (Canada); Van Goethem, G. [European Commission, Brussels (Belgium)

    2001-07-01

    This paper presents an overview of the European Union PARSOAR project, which consists in carrying out a state of the art on hydrogen passive auto-catalytic recombiner (PAR) and a handbook guide for implementing these devices in nuclear power plants. This work is performed in the area ''Operational Safety of Existing Installations'' of the key action ''Nuclear Fission'' of the fifth Euratom Framework Programme (1998-2002). (author)

  18. Novel silver-doped NiTiO3: auto-combustion synthesis ...

    African Journals Online (AJOL)

    Novel silver-doped NiTiO3: auto-combustion synthesis, characterization and photovoltaic measurements. ... To fabricate a FTO/TiO2/Ag-NiTiO3/Pt-FTO solar cell, Ag-NiTiO3 film was directly deposited on top of the TiO2 prepared by electrophoresis deposition method. Furthermore, solar cell result indicates that an ...

  19. A bronchial fibroepithelial polyp with abnormal findings on auto?fluorescence imaging

    OpenAIRE

    Saito, Naomi; Yamasaki, Masahiro; Daido, Wakako; Ishiyama, Sayaka; Deguchi, Naoko; Taniwaki, Masaya

    2017-01-01

    Bronchial fibroepithelial polyps represent a rare type of tumour that displays endobronchial growth. The findings of these lesions on auto?fluorescence imaging (AFI) bronchoscopy have not been reported, despite the usefulness of AFI in detecting early lung cancer. We report the case of a patient with a bronchial fibroepithelial polyp that displayed positivity (magenta colour) on AFI. The patient was a 65?year?old man, in whom an endobronchial polypoid lesion of 10?mm diameter had been detecte...

  20. Influence of fuel ratios on auto combustion synthesis of barium ferrite ...

    Indian Academy of Sciences (India)

    Abstract. Single-domain barium ferrite nano particles have been synthesized with narrow particle-size distribution using an auto combustion technique. In this process, citric acid was used as a fuel. Ratios of cation to fuel were maintained variously at 1 : 1, 1 : 2 and 1 : 3. The pH was 7 in all cases. Of all three cases, a cation ...

  1. Epinephrine auto-injector prescriptions to food-allergic patients in primary care in The Netherlands

    OpenAIRE

    Saleh-Langenberg, Jacquelien; Dubois, A. E. J.; Groenhof, F.; Kocks, J. W. H.; van der Molen, T.; Flokstra-de Blok, B. M. J.

    2015-01-01

    Background The knowledge of general practitioner(s) (GPs) regarding food allergy and anaphylaxis and practices in the prescription of epinephrine auto-injector(s) (EAIs) among GPs has previously only been studied using questionnaires and hypothetical cases. Therefore, there are currently no data as to whether or not GPs prescribe EAIs to high risk food-allergic patients presenting to primary care practices. The aim of this study was therefore to describe and evaluate practice in EAI prescript...

  2. A fast auto-focusing method of microscopic imaging based on an improved MCS algorithm

    OpenAIRE

    Guangkai Fu; Yiping Cao; Mingteng Lu

    2015-01-01

    An improved "three steps" mountain-climb searching (MCS) algorithm is proposed which is applied to auto-focusing for microscopic imaging accurately and efficiently. By analyzing the performance of several evaluation functions, the variance function and the Brenner function are synthesized as a new evaluation function. In the first step, a self-adaptive step length which is much dependent on the reciprocal of the evaluation function value at the beginning position of climbing is used for appro...

  3. Auto adaptation incluant une double mobilité logicielle et physique ...

    African Journals Online (AJOL)

    Dans ce papier, nous étudions les possibilités d'auto adaptation que pourrait offrir un calcul réparti incluant une double mobilité : d'une part une mobilité physique des sites supports d'exécution et, d'autre part, une mobilité des composants logiciels métiers ou clients. Cette mobilité de niveau logiciel est envisagée dans le ...

  4. Administration of the adrenaline auto-injector at the nursery/kindergarten/school in Western Japan

    OpenAIRE

    Korematsu, Seigo; Fujitaka, Michiko; Ogata, Mika; Zaitsu, Masafumi; Motomura, Chikako; Kuzume, Kazuyo; Toku, Yuchiro; Ikeda, Masanori; Odajima, Hiroshi

    2017-01-01

    Background In view of the increasing prevalence of food allergies, there has been an associated increase in frequency of situations requiring an emergency response for anaphylaxis at the home, childcare facilities and educational institutions. Objective To clarify the situation of adrenaline auto-injector administration in nursery/kindergarten/school, we carried out a questionnaire survey on pediatric physicians in Western Japan. Methods In 2015, self-reported questionnaires were mailed to 42...

  5. Anaphylaxis and epinephrine auto-injector training: who will teach the teachers?

    Science.gov (United States)

    Grouhi, M; Alshehri, M; Hummel, D; Roifman, C M

    1999-07-01

    Anaphylaxis is the most urgent clinical immunologic event. Effective treatment is best achieved by administration of epinephrine. Accidental exposure to the responsible allergen is the most common cause of anaphylaxis, and because it could be fatal within minutes, epinephrine in preloaded syringes and auto-injectors has been introduced. In our experience patients and medical personnel are not familiar with the use of this device. We sought to assess community-based professionals' knowledge of epinephrine auto-injector use and their ability to educate patients. Study participants consisted of a medical convention's delegates and emergency department personnel in metropolitan Toronto, as well as pharmacists of the target hospitals and retail pharmacists. Research assistants approached eligible professionals to fill out a questionnaire and demonstrate their ability to use a standard placebo auto-injector trainer. A total of 122 professionals (composed of emergency physicians, family practitioners, and pediatricians) consented to participate in this study. The majority of participants (81%) did not have a placebo trainer to educate their patients; 76% did not know the 2 available dose strengths. To provide instructions and reinforcement, physicians clearly must have the necessary skills and knowledge, yet only 25% of the study participants were able to demonstrate the 3 steps of injection correctly. Our study highlights a specific and important deficiency in medical professionals' care of patients at risk for anaphylaxis. The results challenge the current methods of educating professionals, as well as patients, when prescribing or using epinephrine auto-injectors. Clearly a new approach to educating and maintaining such skills is required.

  6. Effects of methyl substitution on the auto-ignition of C16 alkanes

    KAUST Repository

    Lapuerta, Magín

    2015-12-18

    The auto-ignition quality of diesel fuels, quantified by their cetane number or derived cetane number (DCN), is a critical design property to consider when producing and upgrading synthetic paraffinic fuels. It is well known that auto-ignition characteristics of paraffinic fuels depend on their degree of methyl substitution. However, there remains a need to study the governing chemical functionalities contributing to such ignition characteristics, especially in the case of methyl substitutions, which have not been studied in detail. In this work, the auto-ignition of 2,6,10-trimethyltridecane has been compared with the reference hydrocarbons used for cetane number determination, i.e. n-hexadecane and heptamethylnonane, all of them being C16 isomers. Results from a constant-volume combustion chamber under different pressure and temperature initial conditions showed that the ignition delay time for both cool flame and main combustion events increased less from n-hexadecane to trimethyltridecane than from trimethyltridecane to heptamethylnonane. Additional experimental results from blends of these hydrocarbons, together with kinetic modelling, showed that auto-ignition times and combustion rates were correlated to the concentration of the functional groups indicative of methyl substitution, although not in a linear manner. When the concentration of these functional groups decreased, the first stage OH radical concentration increased and ignition delay times decreased, whereas when their concentration increased, H2O2 production was slower and ignition was retarded. Contrary to the ignition delay times, DCN was correlated linearly with functional groups, thus homogenizing the range of values and clarifying the differences between fuels.

  7. Facial expression recognition based on improved local ternary pattern and stacked auto-encoder

    Science.gov (United States)

    Wu, Yao; Qiu, Weigen

    2017-08-01

    In order to enhance the robustness of facial expression recognition, we propose a method of facial expression recognition based on improved Local Ternary Pattern (LTP) combined with Stacked Auto-Encoder (SAE). This method uses the improved LTP extraction feature, and then uses the improved depth belief network as the detector and classifier to extract the LTP feature. The combination of LTP and improved deep belief network is realized in facial expression recognition. The recognition rate on CK+ databases has improved significantly.

  8. Multi-atlas segmentation of subcortical brain structures via the AutoSeg software pipeline

    Science.gov (United States)

    Wang, Jiahui; Vachet, Clement; Rumple, Ashley; Gouttard, Sylvain; Ouziel, Clémentine; Perrot, Emilie; Du, Guangwei; Huang, Xuemei; Gerig, Guido; Styner, Martin

    2014-01-01

    Automated segmenting and labeling of individual brain anatomical regions, in MRI are challenging, due to the issue of individual structural variability. Although atlas-based segmentation has shown its potential for both tissue and structure segmentation, due to the inherent natural variability as well as disease-related changes in MR appearance, a single atlas image is often inappropriate to represent the full population of datasets processed in a given neuroimaging study. As an alternative for the case of single atlas segmentation, the use of multiple atlases alongside label fusion techniques has been introduced using a set of individual “atlases” that encompasses the expected variability in the studied population. In our study, we proposed a multi-atlas segmentation scheme with a novel graph-based atlas selection technique. We first paired and co-registered all atlases and the subject MR scans. A directed graph with edge weights based on intensity and shape similarity between all MR scans is then computed. The set of neighboring templates is selected via clustering of the graph. Finally, weighted majority voting is employed to create the final segmentation over the selected atlases. This multi-atlas segmentation scheme is used to extend a single-atlas-based segmentation toolkit entitled AutoSeg, which is an open-source, extensible C++ based software pipeline employing BatchMake for its pipeline scripting, developed at the Neuro Image Research and Analysis Laboratories of the University of North Carolina at Chapel Hill. AutoSeg performs N4 intensity inhomogeneity correction, rigid registration to a common template space, automated brain tissue classification based skull-stripping, and the multi-atlas segmentation. The multi-atlas-based AutoSeg has been evaluated on subcortical structure segmentation with a testing dataset of 20 adult brain MRI scans and 15 atlas MRI scans. The AutoSeg achieved mean Dice coefficients of 81.73% for the subcortical structures

  9. Optimal Operation of Microgrids Considering Auto-Configuration Function Using Multiagent System

    OpenAIRE

    Van-Hai Bui; Akhtar Hussain; Hak-Man Kim

    2017-01-01

    Monitoring the status of existing devices and identification of newly added devices is required in microgrids to adjust the operation schedule followed by any event or integration of a new device. Therefore, in this paper, automatic reconfiguration of microgrids is considered after the addition of a new device or change in the operation status of an existing device by using a multiagent system. This capability of the microgrid is named as auto-configuration function, which is performed by the...

  10. Auto-antibodies and their association with clinical findings in women diagnosed with microscopic colitis.

    Directory of Open Access Journals (Sweden)

    Bodil Roth

    Full Text Available BACKGROUND: Microscopic colitis (MC is a disease manifested by diarrhoea and is divided into collagenous and lymphocytic colitis. The aetiology is unknown, but auto-immunity is suggested. Auto-antibodies have been only rarely examined in this entity. The aim of the study was to examine the prevalence of auto-antibodies, and to examine associations between the presence of antibodies and clinical findings. METHODS AND FINDINGS: Women with MC verified by biopsy and younger than 73 years, at any Department of Gastroenterology, in the district of Skåne, between 2002 and 2010 were invited to participate in this study. The patients were asked to complete both a questionnaire describing their medical history and the Gastrointestinal Symptom Rating Scale (GSRS. Blood samples were collected. Anti-nuclear antibodies (ANA, anti-neutrophil cytoplasmic antibodies (ANCA, anti-Saccharomyces cerevisiae antibodies (ASCA, and antibodies against glutamic acid decarboxylase (anti-GAD, islet antigens-like insulin 2 (anti-IA2, thyroid peroxidase (anti-TPO, and thyrotropin receptor (TRAK were analysed. Of 240 women identified, 133 were finally included in the study, median age 63 (59-67 years. Apart from the MC diagnosis, 52% also suffered from irritable bowel syndrome, 31% from hypertension and 31% from allergy. The prevalence of ANA (14%, ASCA IgG (13%, and anti-TPO antibodies (14% for these patients was slightly higher than for the general population, and were found together with other concomitant diseases. Patients had more of all gastrointestinal symptoms compared with norm values, irrespective of antibody expression. CONCLUSIONS: Women with MC have a slightly increased prevalence of some auto-antibodies. These antibodies are not associated with symptoms, but are expressed in patients with concomitant diseases, obscuring the pathophysiology and clinical picture of MC.

  11. Comparison of the robustness and functionality of three adrenaline auto-injectors

    OpenAIRE

    Schwirtz, Andreas; Seeger, H

    2012-01-01

    Andreas Schwirtz, Harald SeegerPharma Consult GmbH, Vienna, AustriaBackground: Anaphylaxis is a medical emergency that requires the intramuscular injection of adrenaline using an adrenaline auto-injector (AAI). This study compared the robustness and performance characteristics of three AAIs available in Europe.Methods: Three AAIs (Jext®, EpiPen®, and Anapen®) were tested in terms of the force needed to activate the AAIs, exposed needle length, injection volume, and inj...

  12. Getting full control of canonical correlation analysis with the AutoBiplot.CCA function

    Science.gov (United States)

    Alves, M. Rui

    2016-06-01

    Function AutoBiplot.CCA was built in R language. Given two multivariate data sets, this function carries out a conventional canonical correlation analysis, followed by the automatic production of predictive biplots based on the accuracy of readings as assessed by a mean standard predictive error and a user defined tolerance value. As the user's intervention is mainly restricted to the choice of the magnitude of the t.axis value, common misinterpretations, overestimations and adjustments between outputs and personal beliefs are avoided.

  13. Elimination de l'auto-modulation de phase dans un amplificateur optique à fibre

    OpenAIRE

    Audo, Frederic; Boscolo, Sonia; Fatome, Julien; Kibler, Bertrand; Finot, Christophe

    2017-01-01

    Nous proposons et démontrons expérimentalement une nouvelle technique simple et efficace pour combattre l’auto-modulation de phase qui dégrade les performances des amplificateurs à fibre. En appliquant une modulation de phase temporelle sinusoïdale, nous éliminons ainsi quasi-totalement l’élargissement spectral causé par l’effet Kerr.

  14. The filling-in function of the Bayesian AutoEncoder Network

    Science.gov (United States)

    Nishino, Kaneharu; Inaba, Mary

    2017-06-01

    We developed the Bayesian AutoEncoder (BAE) to construct a multi-layer restricted Bayesian Network by extracting features from a training dataset. Networks constructed using BAE have hidden variables that represent features of the data and can execute inferences for each feature. In this paper, we show that a network constructed by BAE can not only recognize features but can also fill in lacking data. We performed experiments and confirmed this filling-in ability.

  15. Apoio social e auto-exame das mamas no Estudo Pró-Saúde

    Directory of Open Access Journals (Sweden)

    Griep Rosane Harter

    2005-01-01

    Full Text Available Os autores investigaram a associação entre a freqüência relatada do auto-exame das mamas e cinco dimensões de apoio social (material, emocional, afetivo, de informação e interação social positiva entre 2.240 funcionárias de uma universidade no Rio de Janeiro, participantes da Fase 1 de um estudo de coorte (Estudo Pró-Saúde. A coleta de informações foi feita por intermédio de um questionário autopreenchível. A realização do auto-exame das mamas "todo mês" ou "quase todo mês" foi relatada por 43% das funcionárias; 24% informaram praticá-lo "raramente" ou "nunca". As participantes com escores mais altos nas cinco dimensões de apoio social relataram freqüência mais elevada de auto-exame das mamas. Em todas as dimensões, a chance de praticar o auto-exame foi aproximadamente duas vezes maior entre aquelas situadas no tercil superior, e cerca de 50% mais elevada entre aquelas no tercil intermediário, quando comparadas às participantes situadas no tercil inferior dos escores de apoio social (teste para tendência linear: p < 0,001. A consistência dos resultados sugere que diversas dimensões de apoio social podem contribuir positivamente para a prática regular de autocuidados de saúde.

  16. Intraoperative Near-infrared Imaging for Parathyroid Gland Identification by Auto-fluorescence: A Feasibility Study.

    Science.gov (United States)

    De Leeuw, Frederic; Breuskin, Ingrid; Abbaci, Muriel; Casiraghi, Odile; Mirghani, Haïtham; Ben Lakhdar, Aïcha; Laplace-Builhé, Corinne; Hartl, Dana

    2016-09-01

    Parathyroid glands (PGs) can be particularly hard to distinguish from surrounding tissue and thus can be damaged or removed during thyroidectomy. Postoperative hypoparathyroidism is the most common complication after thyroidectomy. Very recently, it has been found that the parathyroid tissue shows near-infrared (NIR) auto-fluorescence which could be used for intraoperative detection, without any use of contrast agents. The work described here presents a histological validation ex vivo of the NIR imaging procedure and evaluates intraoperative PG detection by NIR auto-fluorescence using for the first time to our knowledge a commercially available clinical NIR imaging device. Ex vivo study on resected operative specimens combined with a prospective in vivo study of consecutive patients who underwent total or partial thyroid, or parathyroid surgery at a comprehensive cancer center. During surgery, any tissue suspected to be a potential PG by the surgeon was imaged with the Fluobeam 800 (®) system. NIR imaging was compared to conventional histology (ex vivo) and/or visual identification by the surgeon (in vivo). We have validated NIR auto-fluorescence with an ex vivo study including 28 specimens. Sensitivity and specificity were 94.1 and 80 %, respectively. Intraoperative NIR imaging was performed in 35 patients and 81 parathyroids were identified. In 80/81 cases, the fluorescence signal was subjectively obvious on real-time visualization. We determined that PG fluorescence is 2.93 ± 1.59 times greater than thyroid fluorescence in vivo. Real-time NIR imaging based on parathyroid auto-fluorescence is fast, safe, and non-invasive and shows very encouraging results, for intraoperative parathyroid identification.

  17. Piropos hacia las mujeres y auto-cosificación: Las consecuencias perversas de conductas aparentemente halagadoras

    National Research Council Canada - National Science Library

    Alba Moya-Garófano

    2016-01-01

    ...-cosificación de las mujeres, por un lado, y sus evaluaciones y reacciones ante un piropo (una situación de cosificación), por otro. Los resultados muestran un nuevo efecto pernicioso de la auto...

  18. Auto-flotation of heterocyst enables the efficient production of renewable energy in cyanobacteria.

    Science.gov (United States)

    Chen, Ming; Li, Jihong; Zhang, Lei; Chang, Sandra; Liu, Chen; Wang, Jianlong; Li, Shizhong

    2014-02-06

    Utilizing cyanobacteria as a bioenergy resource is difficult due to the cost and energy consuming harvests of microalgal biomass. In this study, an auto-floating system was developed by increasing the photobiological H2 production in the heterocysts of filamentous cyanobacteria. An amount of 1.0 μM of diuron, which inhibited O2 production in cyanobacteria, resulted in a high rate of H2 production in heterocysts. The auto-floating process recovered 91.71% ± 1.22 of the accumulated microalgal biomass from the liquid media. Quantification analysis revealed that 0.72-1.10 μmol H2 per mg dry weight microalgal biomass was necessary to create this auto-floating system. Further bio-conversion by using anaerobic digestion converted the harvested microalgal biomass into biogas. Through this novel coupled system of photobiological H2 production and anaerobic digestion, a high level of light energy conversion efficiency from solar energy to bioenergy was attained with the values of 3.79% ± 0.76.

  19. Lagged Poincar\\'{e} and auto-correlation analysis of Heart rate variability in diabetes

    CERN Document Server

    Ghatak, S K

    2010-01-01

    The heart rate variability (HRV) in diabetic human subjects, has been analyzed using lagged Poincar\\'{e} plot, auto-correlation and the detrended fluctuation analysis methods. The parameters $SD1$, and $SD12 (= SD1/SD2)$ for Poincar\\'{e} plot for diabetic are lower than that for non-diabetic subjects and reverse is case for $SD2$ for all lagged number (m). The slope and the curvature of the plot SD12 vs m is much reduced for diabetic subject. The scatter plot of two successive interbeat intervals points out smaller variability in diabetic heart. The detrended fluctuation exponent has a higher value for diabetic group. The auto-correlation function of the deviation of interbeat interval in diabetic group shows highly correlated pattern when compared to that of normal one. The study suggests that the curvature of $SD12$ and auto-correlation method appear to be better way to assess the alteration of regulatory system on heart dynamics in diabetic condition.

  20. A novel auto-tuning method for fractional order PI/PD controllers.

    Science.gov (United States)

    De Keyser, Robin; Muresan, Cristina I; Ionescu, Clara M

    2016-05-01

    Fractional order PID controllers benefit from an increasing amount of interest from the research community due to their proven advantages. The classical tuning approach for these controllers is based on specifying a certain gain crossover frequency, a phase margin and a robustness to gain variations. To tune the fractional order controllers, the modulus, phase and phase slope of the process at the imposed gain crossover frequency are required. Usually these values are obtained from a mathematical model of the process, e.g. a transfer function. In the absence of such model, an auto-tuning method that is able to estimate these values is a valuable alternative. Auto-tuning methods are among the least discussed design methods for fractional order PID controllers. This paper proposes a novel approach for the auto-tuning of fractional order controllers. The method is based on a simple experiment that is able to determine the modulus, phase and phase slope of the process required in the computation of the controller parameters. The proposed design technique is simple and efficient in ensuring the robustness of the closed loop system. Several simulation examples are presented, including the control of processes exhibiting integer and fractional order dynamics. Copyright © 2016 ISA. Published by Elsevier Ltd. All rights reserved.

  1. A fast auto-focusing method of microscopic imaging based on an improved MCS algorithm

    Directory of Open Access Journals (Sweden)

    Guangkai Fu

    2015-09-01

    Full Text Available An improved "three steps" mountain-climb searching (MCS algorithm is proposed which is applied to auto-focusing for microscopic imaging accurately and efficiently. By analyzing the performance of several evaluation functions, the variance function and the Brenner function are synthesized as a new evaluation function. In the first step, a self-adaptive step length which is much dependent on the reciprocal of the evaluation function value at the beginning position of climbing is used for approaching the halfway up the mountain roughly. Secondly, a fixed moderate step length is applied for approaching the mountaintop of the variance function as closer as possible. Finally, a fine step is employed for reaching the exact mountaintop of the Brenner function. The microscope auto-focusing experiments based on the proposed algorithm for blood smear detection have been carried out comprehensively. The results show that the improved algorithm can not only guarantee the precision to get clear focal images, but also improve the auto-focusing efficiency.

  2. Civilian adult self injections of atropine-trimedoxime (TMB4) auto-injectors.

    Science.gov (United States)

    Bentur, Yedidia; Layish, Ido; Krivoy, Amir; Berkovitch, Matitiahu; Rotman, Eran; Haim, Shmuel Bar; Yehezkelli, Yoav; Kozer, Eran

    2006-01-01

    The clinical effects of self injections of atropine-trimedoxime auto-injectors distributed to the civilian population as a field antidote for nerve agent attack were assessed. Data on self injections by adults (> or = 18 years) were collected from the Israel Poison Information Center and a hospital Emergency Department's records during a 2-year period. The data included demographics, time interval from injection, type of auto-injector, clinical manifestations and atropinization score. Sixty-five patients, all with unintentional self injections, were reported. Systemic atropine effects were observed in 24 patients, but no severe atropinization. The atropinization score was significantly higher in the 2 mg atropine dose group than in the two lower dose groups, which were in the normal range. No specific adverse effects attributable to trimedoxime were observed. Intravenous fluids and physostigmine were not required. Only mild reactions were observed following self-injection of atropine trimedoxime auto-injectors in adults, attesting to their relative safety under these conditions.

  3. A dedicated on-line detecting system for auto air dryers

    Science.gov (United States)

    Shi, Chao-yu; Luo, Zai

    2013-10-01

    According to the correlative automobile industry standard and the requirements of manufacturer, this dedicated on-line detecting system is designed against the shortage of low degree automatic efficiency and detection precision of auto air dryer in the domestic. Fast automatic detection is achieved by combining the technology of computer control, mechatronics and pneumatics. This system can detect the speciality performance of pressure regulating valve and sealability of auto air dryer, in which online analytical processing of test data is available, at the same time, saving and inquiring data is achieved. Through some experimental analysis, it is indicated that efficient and accurate detection of the performance of auto air dryer is realized, and the test errors are less than 3%. Moreover, we carry out the type A evaluation of uncertainty in test data based on Bayesian theory, and the results show that the test uncertainties of all performance parameters are less than 0.5kPa, which can meet the requirements of operating industrial site absolutely.

  4. [Trial digitalization of analog-data obtained from the AutoAnalyzer].

    Science.gov (United States)

    Omori, S

    2000-10-01

    The AutoAnalzer(Basic Model) manufactured on Technicon corporation was a very useful instrument for clinical laboratory automation, but it was necessary to convert the data obtained from the instrument to digital values used the chart reader. This was very troublesome and there was apprehension that there would be errors in A-D conversion. We tried converting data obtained from the AutoAnalzer to a digital value by on-line connection of the instruments with minicomputers(LINC-8 and FACOM-R). The output of the recorder was converted to voltage(0 to 100 V) using a potentiometer, quantitated(0 to 1.000) by the A-D converter attached to LINC-8, and processed by the minicomputer. The control-box was an experimental device mainly designed for the convenience of users. The functions of the control-box were designated analytical items, No. of A-D converters, start and stop of the AutoAnalzer operation to the minicomputer. Employing the control-box, a technician operated this system freely, without direct computer operation. We established a generally satisfactory system for clinical laboratory automation using the minicomputer.

  5. Evaluation of segmentation methods on head and neck CT: Auto-segmentation challenge 2015.

    Science.gov (United States)

    Raudaschl, Patrik F; Zaffino, Paolo; Sharp, Gregory C; Spadea, Maria Francesca; Chen, Antong; Dawant, Benoit M; Albrecht, Thomas; Gass, Tobias; Langguth, Christoph; Lüthi, Marcel; Jung, Florian; Knapp, Oliver; Wesarg, Stefan; Mannion-Haworth, Richard; Bowes, Mike; Ashman, Annaliese; Guillard, Gwenael; Brett, Alan; Vincent, Graham; Orbes-Arteaga, Mauricio; Cárdenas-Peña, David; Castellanos-Dominguez, German; Aghdasi, Nava; Li, Yangming; Berens, Angelique; Moe, Kris; Hannaford, Blake; Schubert, Rainer; Fritscher, Karl D

    2017-05-01

    Automated delineation of structures and organs is a key step in medical imaging. However, due to the large number and diversity of structures and the large variety of segmentation algorithms, a consensus is lacking as to which automated segmentation method works best for certain applications. Segmentation challenges are a good approach for unbiased evaluation and comparison of segmentation algorithms. In this work, we describe and present the results of the Head and Neck Auto-Segmentation Challenge 2015, a satellite event at the Medical Image Computing and Computer Assisted Interventions (MICCAI) 2015 conference. Six teams participated in a challenge to segment nine structures in the head and neck region of CT images: brainstem, mandible, chiasm, bilateral optic nerves, bilateral parotid glands, and bilateral submandibular glands. This paper presents the quantitative results of this challenge using multiple established error metrics and a well-defined ranking system. The strengths and weaknesses of the different auto-segmentation approaches are analyzed and discussed. The Head and Neck Auto-Segmentation Challenge 2015 was a good opportunity to assess the current state-of-the-art in segmentation of organs at risk for radiotherapy treatment. Participating teams had the possibility to compare their approaches to other methods under unbiased and standardized circumstances. The results demonstrate a clear tendency toward more general purpose and fewer structure-specific segmentation algorithms. © 2017 American Association of Physicists in Medicine.

  6. Preferential recognition of auto-antibodies against 4-hydroxynonenal modified DNA in the cancer patients.

    Science.gov (United States)

    Faisal, Mohammad; Shahab, Uzma; Alatar, Abdulrahman A; Ahmad, Saheem

    2017-11-01

    The structural perturbations in DNA molecule may be caused by a break in a strand, a missing base from the backbone, or a chemically changed base. These alterations in DNA that occurs naturally can result from metabolic or hydrolytic processes. DNA damage plays a major role in the mutagenesis, carcinogenesis, aging and various other patho-physiological conditions. DNA damage can be induced through hydrolysis, exposure to reactive oxygen species (ROS) and other reactive carbonyl metabolites including 4-hydroxynonenal (HNE). 4-HNE is an important lipid peroxidation product which has been implicated in the mutagenesis and carcinogenesis processes. The present study examines to probe the presence of auto-antibodies against 4-hydroxynonenal damaged DNA (HNE-DNA) in various cancer subjects. In this study, the purified calf thymus DNA was damaged by the action of 4-HNE. The DNA was incubated with 4-HNE for 24 h at 37°C temperature. The binding characteristics of cancer auto-antibodies were assessed by direct binding and competitive inhibition ELISA. DNA modifications produced hyperchromicity in UV spectrum and decreased fluorescence intensity. Cancer sera exhibited enhanced binding with the 4-HNE modified calf thymus DNA as compared to its native conformer. The 4-HNE modified DNA presents unique epitopes which may be one of the factors for the auto-antibody induction in cancer patients. The HNE modified DNA presents unique epitopes which may be one of the factors for the autoantibody induction in cancer patients. © 2017 Wiley Periodicals, Inc.

  7. Enfermedad poliquística autosómica recesiva Recessive autosomal polycystic disease

    Directory of Open Access Journals (Sweden)

    Sandalio Durán Álvarez

    2007-06-01

    Full Text Available Como enfermedades renales poliquísticas hereditarias se describen clásicamente la autosómica recesiva y la autosómica dominante, mal llamadas enfermedad poliquística de tipo infantily de;tipo adulto, respectivamente, pues ambas pueden verse tanto en una como en otra edad. Los conceptos cambiantes en cuanto a la enfermedad autosómica recesiva, dados por los progresos en el tratamiento de los recién nacidos con la enfermedad, y la localización del gen, que por su mutación la produce, nos motivan hacer esta breve revisión con la finalidad de contribuir a la comprensión de la enfermedad por los estudiantes de medicina y el médico general básico.Recessive autosomal and dominant autosomal polycystic kidney diseases are classically described as hereditary illnesses; they are also called polycystic disease of child type” and of adult typerespectively since both may be seen in any of these two life stages. The changing concepts of recessive autosomal disease, given the advances made in the treatment of newborns with this disease, and the location of the gen, the mutation of which causes it, encouraged us to make a brief literature review to help medical students and general practitioners to understand this disease.

  8. 3D printed auto-mixing chip enables rapid smartphone diagnosis of anemia.

    Science.gov (United States)

    Plevniak, Kimberly; Campbell, Matthew; Myers, Timothy; Hodges, Abby; He, Mei

    2016-09-01

    Clinical diagnosis requiring central facilities and site visits can be burdensome for patients in resource-limited or rural areas. Therefore, development of a low-cost test that utilizes smartphone data collection and transmission would beneficially enable disease self-management and point-of-care (POC) diagnosis. In this paper, we introduce a low-cost i POC 3D diagnostic strategy which integrates 3D design and printing of microfluidic POC device with smartphone-based disease diagnosis in one process as a stand-alone system, offering strong adaptability for establishing diagnostic capacity in resource-limited areas and low-income countries. We employ smartphone output (AutoCAD 360 app) and readout (color-scale analytical app written in-house) functionalities for rapid 3D printing of microfluidic auto-mixers and colorimetric detection of blood hemoglobin levels. The auto-mixing of reagents with blood via capillary force has been demonstrated in 1 second without the requirement of external pumps. We employed this i POC 3D system for point-of-care diagnosis of anemia using a training set of patients (n anemia  = 16 and n healthy  = 6), which showed consistent measurements of blood hemoglobin levels (a.u.c. = 0.97) and comparable diagnostic sensitivity and specificity, compared with standard clinical hematology analyzer. Capable of 3D fabrication flexibility and smartphone compatibility, this work presents a novel diagnostic strategy for advancing personalized medicine and mobile healthcare.

  9. A pilot study assessing adherence to auto-bilevel following a poor initial encounter with CPAP.

    Science.gov (United States)

    Powell, Eric D; Gay, Peter C; Ojile, Joseph M; Litinski, Mikhail; Malhotra, Atul

    2012-02-15

    We hypothesized that early intervention with an auto bilevel device would improve treatment adherence compared to CPAP among OSA patients with a poor initial experience with lab-based CPAP titration. Patients with a poor initial CPAP experience were recruited for this parallel group, randomized, double-blind, controlled pilot study. After an in-lab titration, patients were randomized with either an auto-bilevel device or CPAP. Treatment adherence and functioning were assessed at 90 days. We enrolled 51 subjects, with 47 completing the protocol. Groups were equally matched for gender, age, education, and OSA severity. There was no significant difference in the proportion of compliant subjects (≥ 4 h/night) between the auto bilevel and CPAP groups (62% vs. 54%; p = 0.624) after 90 days of use. Functional outcomes significantly improved in both groups during treatment use (p CPAP groups in this study. Patients with a poor initial CPAP exposure may still achieve an acceptable long-term clinical outcome. Both groups demonstrated comparably significant improvements in functional outcomes, sleepiness, and fatigue complaints over the treatment period. CLINICAL TRIALS INFORMATION: NCT00635206 ClinicalTrials.gov

  10. La Distracción de Sí. Jacques Derrida y la Auto-Afección

    Directory of Open Access Journals (Sweden)

    Cristóbal Durán

    2015-08-01

    Full Text Available En este texto buscamos hacer inteligible el lugar y los derroteros que sigue el concepto de auto-afección en el pensamiento de Jacques Derrida. Dicho concepto se desarrolla a partir de una interpretación de Kant y el problema de la metafísica, de Heidegger. En la elaboración del concepto en Derrida se enfatiza el momento de distancia en el que el sí-mismo no puede reducir al otro, sino que tiene que hacer patente la demora en su propia formación. Esto implicaría considerar que la mismidad que se constituye en la auto-afección no puede ser separada de una hetero-afección, mediante la cual el otro no puede ser objetivado y no es otra cosa que el sí-mismo en su alteración. La forma de dicho espaciamiento que produce la alteración se pone a prueba en la voz y en la estructura del “oírse-hablar”, la que se revela como un espacio polifónico irreductible a una unidad, donde la auto-afección se desune de sí para retornar como aquello que no espera y como aquello que no puede replegarse en un lugar de reunión.

  11. Hierarchical auto-configuration addressing in mobile ad hoc networks (HAAM)

    Science.gov (United States)

    Ram Srikumar, P.; Sumathy, S.

    2017-11-01

    Addressing plays a vital role in networking to identify devices uniquely. A device must be assigned with a unique address in order to participate in the data communication in any network. Different protocols defining different types of addressing are proposed in literature. Address auto-configuration is a key requirement for self organizing networks. Existing auto-configuration based addressing protocols require broadcasting probes to all the nodes in the network before assigning a proper address to a new node. This needs further broadcasts to reflect the status of the acquired address in the network. Such methods incur high communication overheads due to repetitive flooding. To address this overhead, a new partially stateful address allocation scheme, namely Hierarchical Auto-configuration Addressing (HAAM) scheme is extended and proposed. Hierarchical addressing basically reduces latency and overhead caused during address configuration. Partially stateful addressing algorithm assigns addresses without the need for flooding and global state awareness, which in turn reduces the communication overhead and space complexity respectively. Nodes are assigned addresses hierarchically to maintain the graph of the network as a spanning tree which helps in effectively avoiding the broadcast storm problem. Proposed algorithm for HAAM handles network splits and merges efficiently in large scale mobile ad hoc networks incurring low communication overheads.

  12. Adrenaline auto-injectors for the treatment of anaphylaxis with and without cardiovascular collapse in the community.

    Science.gov (United States)

    Sheikh, Aziz; Simons, F Estelle R; Barbour, Victoria; Worth, Allison

    2012-08-15

    Anaphylaxis is a serious hypersensitivity reaction that is rapid in onset and may cause death. Adrenaline (epinephrine) auto-injectors are recommended as the initial, potentially life-saving treatment of choice for anaphylaxis in the community, but they are not universally available and have limitations in their use. To assess the effectiveness of adrenaline (epinephrine) auto-injectors in relieving respiratory, cardiovascular, and other symptoms during episodes of anaphylaxis that occur in the community. We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2012, Issue 1), MEDLINE (Ovid SP) (1950 to January 2012), EMBASE (Ovid SP) (1980 to January 2012 ), CINAHL (EBSCO host) (1982 to January 2012 ), AMED (EBSCO host) (1985 to January 2012 ), LILACS, (BIREME) (1980 to January 2012 ), ISI Web of Science (1950 to January 2012 ). We adapted our search terms for other databases. We also searched websites listing on-going trials: the World Health Organization International Clinical Trials Registry Platform, the UK Clinical Research Network Study Portfolio, and the meta Register of Controlled Trials; and contacted pharmaceutical companies who manufacture adrenaline auto-injectors in an attempt to locate unpublished material. Randomized and quasi-randomized controlled trials comparing auto-injector administration of adrenaline with any control including no intervention, placebo, or other adrenergic agonists were eligible for inclusion. Two authors independently assessed articles for inclusion. None of the 1328 studies that were identified satisfied the inclusion criteria. Based on this review, we cannot make any new recommendations on the effectiveness of adrenaline auto-injectors for the treatment of anaphylaxis. Although randomized, double-blind, placebo-controlled clinical trials of high methodological quality are necessary to define the true extent of benefits from the administration of adrenaline in anaphylaxis via an auto

  13. A simple protocol for attenuating the auto-fluorescence of cyanobacteria for optimized fluorescence in situ hybridization (FISH) imaging.

    Science.gov (United States)

    Zeller, Perrine; Ploux, Olivier; Méjean, Annick

    2016-03-01

    Cyanobacteria contain pigments, which generate auto-fluorescence that interferes with fluorescence in situ hybridization (FISH) imaging of cyanobacteria. We describe simple chemical treatments using CuSO4 or H2O2 that significantly reduce the auto-fluorescence of Microcystis strains. These protocols were successfully applied in FISH experiments using 16S rRNA specific probes and filamentous cyanobacteria. Copyright © 2016 Elsevier B.V. All rights reserved.

  14. Anti-pentraxin 3 auto-antibodies might be protective in lupus nephritis: a large cohort study.

    Science.gov (United States)

    Yuan, Mo; Tan, Ying; Pang, Yun; Li, Yong-Zhe; Song, Yan; Yu, Feng; Zhao, Ming-Hui

    2017-11-01

    Anti-pentraxin 3 (PTX3) auto-antibodies were found to be associated with the absence of renal involvement in systemic lupus erythematosus (SLE). This study is to investigate the prevalence of anti-PTX3 auto-antibodies and their clinical significance based on a large Chinese lupus nephritis cohort. One hundred and ninety-six active lupus nephritis patients, 150 SLE patients without clinical renal involvement, and 100 healthy controls were enrolled. Serum anti-PTX3 auto-antibodies and PTX3 levels were screened by enzyme-linked immunosorbent assay (ELISA). The associations between anti-PTX3 auto-antibodies and clinicopathological parameters in lupus nephritis were further analyzed. Anti-PTX3 auto-antibodies were less prevalent in active lupus nephritis patients compared with SLE without renal involvement (19.4% (38/196) versus 40.7% (61/150), p proteinuria in lupus nephritis (r = -.143, p = .047). The levels of proteinuria, serum creatinine, and the prevalence of thrombotic microangiopathy were significantly higher in patients with higher PTX3 levels (≥3.207 ng/ml) and without anti-PTX3 auto-antibodies compared with patients with lower PTX3 levels (<3.207 ng/ml) and with anti-PTX3 auto-antibodies (4.79 (3.39-8.28) versus 3.95 (1.78-7.0), p = .03; 168.84 ± 153.63 versus 101.44 ± 47.36, p = .01; 34.1% (14/41) versus 0% (0/9), p = .04; respectively). Anti-PTX3 auto-antibodies were less prevalent in active lupus nephritis patients compared with SLE without renal involvement and associated with less severe renal damage, especially with the combined evaluation of serum PTX3 levels.

  15. A novel electromechanical autoinjector, AutoTouch™, for self-injection of etanercept: real-world use and benefits.

    Science.gov (United States)

    Collier, David H; Bitman, Bojena; Coles, Andrew; Liu, Lyrica; Kumar, Sandeep; Judd, Clinton

    2017-01-01

    We assessed the ability of patients with autoimmune inflammatory diseases to successfully use the investigational AutoTouch™ reusable autoinjector as well as patient preference for AutoTouch™ versus the currently marketed single-use prefilled etanercept SureClick® autoinjector. Two multicenter studies were performed: a Home Use Study and a Patient Preference Study. In the Home Use Study, 77 patients with rheumatoid arthritis (RA) or psoriatic arthritis self-administered etanercept once weekly for 5 weeks. The primary end point was successful self-injection of etanercept via AutoTouch™. The Patient Preference Study was an open-label, randomized, 8-week crossover trial (4 weeks for each device) in 216 patients with RA or psoriasis (PsO). The primary end point was preference for AutoTouch™ versus SureClick®. In the Home Use Study, the proportion of successful self-injections with AutoTouch™ during weeks 1 through 5 was 97.8% (95% CI, 96.3‒99.3). In the Patient Preference Study, patients had a preference rate for AutoTouch™ of 41.7% (95% CI, 34.9-48.4) overall, 43.5% (95% CI, 35.5‒51.6) for patients with RA, and 36.8% (95% CI, 24.3‒49.4) for patients with PsO. Needle apprehension was not different at initiation of the autoinjectors, nor was there a difference between the injectors after 4 weeks. Overall, patients preferred AutoTouch™ for ease of self-injecting, ease of pressing the start button, ease of following injection progress, and certainty of knowing when the injection was completed. SureClick® was preferred for fewer steps and experiencing less injection site discomfort or pain. The introduction of the AutoTouch™ will give patients a choice between two different autoinjectors for self-administration of etanercept.

  16. Directly auto-transplanted mesenchymal stem cells induce bone formation in a ceramic bone substitute in an ectopic sheep model

    Science.gov (United States)

    Boos, Anja M; Loew, Johanna S; Deschler, Gloria; Arkudas, Andreas; Bleiziffer, Oliver; Gulle, Heinz; Dragu, Adrian; Kneser, Ulrich; Horch, Raymund E; Beier, Justus P

    2011-01-01

    Abstract Bone tissue engineering approaches increasingly focus on the use of mesenchymal stem cells (MSC). In most animal transplantation models MSC are isolated and expanded before auto cell transplantation which might be critical for clinical application in the future. Hence this study compares the potential of directly auto-transplanted versus in vitro expanded MSC with or without bone morphogenetic protein-2 (BMP-2) to induce bone formation in a large volume ceramic bone substitute in the sheep model. MSC were isolated from bone marrow aspirates and directly auto-transplanted or expanded in vitro and characterized using fluorescence activated cell sorting (FACS) and RT-PCR analysis before subcutaneous implantation in combination with BMP-2 and β-tricalcium phosphate/hydroxyapatite (β-TCP/HA) granules. Constructs were explanted after 1 to 12 weeks followed by histological and RT-PCR evaluation. Sheep MSC were CD29+, CD44+ and CD166+ after selection by Ficoll gradient centrifugation, while directly auto-transplanted MSC-populations expressed CD29 and CD166 at lower levels. Both, directly auto-transplanted and expanded MSC, were constantly proliferating and had a decreasing apoptosis over time in vivo. Directly auto-transplanted MSC led to de novo bone formation in a heterotopic sheep model using a β-TCP/HA matrix comparable to the application of 60 μg/ml BMP-2 only or implantation of expanded MSC. Bone matrix proteins were up-regulated in constructs following direct auto-transplantation and in expanded MSC as well as in BMP-2 constructs. Up-regulation was detected using immunohistology methods and RT-PCR. Dense vascularization was demonstrated by CD31 immunohistology staining in all three groups. Ectopic bone could be generated using directly auto-transplanted or expanded MSC with β-TCP/HA granules alone. Hence BMP-2 stimulation might become dispensable in the future, thus providing an attractive, clinically feasible approach to bone tissue engineering. PMID

  17. Complement deposition induced by binding of anti-contactin-1 auto-antibodies is modified by immunoglobulins.

    Science.gov (United States)

    Appeltshauser, Luise; Weishaupt, Andreas; Sommer, Claudia; Doppler, Kathrin

    2017-01-01

    Inflammatory neuropathies associated with auto-antibodies against paranodal proteins like contactin-1 are reported to respond poorly to treatment with intravenous immunoglobulins (IVIG). A reason might be that IVIG interacts with the complement pathway and these auto-antibodies often belong to the IgG4 subclass that does not activate complement. However, some patients do show a response to IVIG, especially at the beginning of the disease. This corresponds with the finding of coexisting IgG subclasses IgG1, IgG2 and IgG3. We therefore aimed to investigate complement deposition and activation by samples of three patients with anti-contactin-1 IgG auto-antibodies of different subclasses as a potential predictor for response to IVIG. Complement deposition and activation was measured by cell binding and ELISA based assays, and the effect of IVIG on complement deposition was assessed by addition of different concentrations of IVIG. Binding of anti-contactin-1 auto-antibodies of all three patients induced complement deposition and activation with the strongest effect shown by the serum of a patient with predominance of IgG3 auto-antibodies. IVIG led to a reduction of complement deposition in a dose-dependent manner, but did not reduce binding of auto-antibodies to contactin-1. We conclude that complement deposition may contribute to the pathophysiology of anti-contactin-1 associated neuropathy, particularly in patients with predominance of the IgG3 subclass. The proportion of different auto-antibody subclasses may be a predictor for the response to IVIG in patients with auto-antibodies against paranodal proteins. Copyright © 2016 Elsevier Inc. All rights reserved.

  18. Controlled auto-ignition characteristics of methane-air mixture in a rapid intake compression and expansion machine

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Gyubaek; Jeong, Dongsoo [Engine Research Team, Eco-Machinery Research Division, Korea Institute of Machinery and Materials, 104 Sinseongno, Yuseong-gu, Daejeon 305-701 (Korea); Moon, Gunfeel [Department of Clean Environmental system, University of Science and Technology, 52 Eoeun-dong, Yuseong-gu, Daejeon (Korea); Bae, Choongsik [Engine Laboratory, Department of Mechanical Engineering, Korea Advanced Institute of Science and Technology, 373-1 GuSeong-Dong, Yuseong-Gu, Daejeon 305-701 (Korea)

    2010-10-15

    The characteristics of controlled auto-ignition (CAI) were investigated with a methane-air mixture and simulated residual gas, that represents internal exhaust gas recirculation (IEGR). Supply systems were additionally installed on the conventional rapid compression machine (RCM), and this modified machine - a rapid intake compression and expansion machine (RICEM) - was able to simulate an intake stroke for the evaluation of controlled auto-ignition with fuel-air mixture. The fuel-air mixture and the simulated residual gas were introduced separately into the combustion chamber through the spool valves. Various IEGR rates and temperatures of the IEGR gas were tested. The initial reaction and the development in controlled auto-ignition combustion were compared with spark-ignited combustion by visualization with a high-speed digital camera. Under the controlled auto-ignition operation, multi-point ignition and faster combustion were observed. With increasing the temperature of IEGR gas, the auto-ignition timing was advanced and burning duration was shortened. The higher rate of IEGR had the same effects on the combustion of the controlled auto-ignition. However, this trend was reversed with more than 47 per cent of IEGR. (author)

  19. Metabolic syndrome and occupation: Any association? Prevalence among auto technicians and school teachers in South West Nigeria.

    Science.gov (United States)

    Akintunde, Adeseye A; Oloyede, Taiwo W

    2017-11-01

    To determine occupational association with metabolic syndrome among auto technicians and school teachers. One hundred and sixty six subjects were selected for this study. Clinical data was obtained while laboratory investigations including plasma glucose and lipid profile were performed. Statistical analysis was done with SPSS 20.0. Pauto technicians. Mean serum triglycerides was significantly higher among auto-technicians compared to school teachers in this study. The prevalence of some conventional cardiovascular risk factors was significantly higher among auto-technicians compared to school teachers: Impaired blood glucose (9.6% vs. 1.2%, pauto-technicians. Based on the WHO and the Harmonized criteria, metabolic syndrome was more frequent among auto-technicians compared to school teachers. (8.4% vs. 1.2% and 19.3% vs. 7.2% respectively, pauto technicians despite their high level of physical activity, exertion and education compared to teachers. This may be related to the increased occupational exposure to organic and inorganic materials from dust particles, oil and oil related matter and particulate matter among auto technicians. Prompt definitive evaluation of this concept and appropriate health education to encourage safety mechanism can reduce this burden of metabolic syndrome among auto technicians in Nigeria. Copyright © 2016 Diabetes India. Published by Elsevier Ltd. All rights reserved.

  20. Auto-Regulatory RNA Editing Fine-Tunes mRNA Re-Coding and Complex Behaviour in Drosophila

    Science.gov (United States)

    Savva, Yiannis A.; Jepson, James E.C; Sahin, Asli; Sugden, Arthur U.; Dorsky, Jacquelyn S.; Alpert, Lauren; Lawrence, Charles; Reenan, Robert A.

    2014-01-01

    Auto-regulatory feedback loops are a common molecular strategy used to optimize protein function. In Drosophila many mRNAs involved in neuro-transmission are re-coded at the RNA level by the RNA editing enzyme dADAR, leading to the incorporation of amino acids that are not directly encoded by the genome. dADAR also re-codes its own transcript, but the consequences of this auto-regulation in vivo are unclear. Here we show that hard-wiring or abolishing endogenous dADAR auto-regulation dramatically remodels the landscape of re-coding events in a site-specific manner. These molecular phenotypes correlate with altered localization of dADAR within the nuclear compartment. Furthermore, auto-editing exhibits sexually dimorphic patterns of spatial regulation and can be modified by abiotic environmental factors. Finally, we demonstrate that modifying dAdar auto-editing affects adaptive complex behaviors. Our results reveal the in vivo relevance of auto-regulatory control over post-transcriptional mRNA re-coding events in fine-tuning brain function and organismal behavior. PMID:22531175

  1. What are the 'ideal' features of an adrenaline (epinephrine) auto-injector in the treatment of anaphylaxis?

    Science.gov (United States)

    Frew, A J

    2011-01-01

    Anaphylaxis is a systemic allergic reaction that often involves respiratory symptoms and cardiovascular collapse, which are potentially life-threatening if not treated promptly with intramuscular adrenaline. Owing to the unpredictable nature of anaphylaxis and accidental exposure to allergens (such as peanuts and shellfish), patients should be prescribed intramuscular adrenaline auto-injectors and carry these with them at all times. Patients also need to be able to use their auto-injectors correctly while under high stress, when an anaphylactic attack occurs. Despite this, an alarming number of patients fail to carry their auto-injectors and many patients, carers of children with known anaphylaxis and healthcare professionals do not know how to use the device correctly, despite having had training. Currently available auto-injector devices have various limitations that may impede their use in the management of anaphylaxis. There is also a lack of validated assessment criteria and regulatory requirements for new devices. This review describes the different delivery systems used in currently available auto-injectors and discusses the key barriers to the use of adrenaline auto-injectors, with the goal of identifying the 'ideal' features/characteristics of such devices in the emergency treatment of anaphylaxis that will ensure ease of use, portability and accurate delivery of a life-saving drug. © 2010 John Wiley & Sons A/S.

  2. MRT letter: Auto-fluorescence by human alveolar macrophages after in vitro exposure to air pollution particles.

    Science.gov (United States)

    Ghio, Andrew J; Sangani, Rahul G; Brighton, Luisa E; Carson, John L

    2010-06-01

    Macrophages from smokers demonstrate an increased auto-fluorescence. Similarly, auto-fluorescence follows in vitro exposure of macrophages to cigarette smoke condensate (i.e., the particulate fraction of cigarette smoke). The composition of particles in cigarette smoke can be comparable to air pollution particles. We tested the postulate that macrophages exposed to air pollution particles could demonstrate auto-fluorescence. Healthy nonsmoking and healthy smoking volunteers (both 18-40 years of age) underwent fiberoptic bronchoscopy with bronchoalveolar lavage and alveolar macrophages isolated. Macrophages were incubated at 37 degrees C in 5% CO(2) with either PBS or 100 microg/mL particle for both 1 and 24 h. Particles included a residual oil fly ash, Mt. St. Helens volcanic ash, and ambient air particles collected from St. Louis, Missouri and Salt Lake City, Utah. At the end of incubation, 50 microL of the cell suspension was cytocentrifuged and examined at modes for viewing fluorescein isothiocyanate (FITC) and rhodamine fluorescence. Both emission source air pollution particles demonstrated FITC and rhodamine auto-fluorescence at 1 and 24 h, but the signal following incubation of the macrophages with oil fly ash appeared greater. Similarly, the ambient particles were associated with auto-fluorescence by the alveolar macrophages and this appeared to be dose-dependent. We conclude that exposure of macrophages to air pollution particles can be associated with auto-fluorescence in the FITC and rhodamine modes. c) 2009 Wiley-Liss, Inc

  3. La criticalité auto-organisée des feux de forêts marocaines

    Directory of Open Access Journals (Sweden)

    Larbi ABIBI

    2014-03-01

    Full Text Available La Criticalité Auto-Organisée (CAO des feux de forêts marocaines est étudiée à partir d’une analyse d’une série de données historiques (1960 à 2011. En effet, cette analyse montre que les relations entre les surfaces brûlées annuelles normalisées par la surface brûlée globale et la fréquence des incendies annuels par la surface brûlée annuelle sont décrites par des distributions en loi en puissance (queue lourde et non en distribution gaussienne (queue mince, et ceci quelque soit la magnitude du feu. Aussi la relation log-log de la fréquence-taille ou « rang-taille » des incendies vérifie son adéquation avec une droite. L’invariance d’échelle temporelle et spatiale des feux est vérifiée. Ainsi les feux de forêts marocaines satisfont la criticalité auto-organisée. Les résultats des données réelles relatives aux feux des forêts marocaines sont confrontés avec ceux des simulations réalisées par notre logiciel « LoSiFire » (automate cellulaire basé sur le « jeu de la Vie », leur bonne adéquation est obtenue. Par conséquent notre logiciel « LoSiFire » s’applique bien et vérifie les caractéristiques de la criticalité auto-organisée. En effet, notre automate cellulaire est un système critique auto-organisé. Enfin les caractéristiques de la criticalité auto-organisée ont des implications pratiques pour la protection des forêts contre les incendies et constituent un moyen d’évaluation et d’élaboration de la stratégie de prévention et de lutte contre les feux de forêts.

  4. The feasibility of the auto tuning respiratory compensation system with ultrasonic image tracking technique.

    Science.gov (United States)

    Chuang, Ho-Chiao; Hsu, Hsiao-Yu; Nieh, Shu-Kan; Tien, Der-Chi

    2015-01-01

    The purpose of this study is to assess the feasibility of using the analytical technique of ultrasound images in combination with an auto tumor localization system. During respiration, the activity of breathing in and out causes organs displacement at the lower lobe of the lung, and the maximum displacement range happens in the Superior-Inferior (SI) direction. Therefore, in this study all the tumor positioning is in SI direction under respiratory compensation, in which the compensations are carried out to the organs at the lower lobe and adjacent to the lower lobe of lung.In this research, due to the processes of ultrasound imaging generation, image analysis and signal transmission, when the captured respiratory signals are sent to auto tumor localization system, there was a signal time delay. The total delay time of the entire signal transmission process was 0.254 ± 0.023 seconds (with the lowest standard deviation) after implementing a series of analyses. To compensate for this signal delay time (0.254 ± 0.023 sec), a phase lead compensator (PLC) was designed and built into the auto tumor localization system. By analyzing the impact of the delay time and the respiratory waveforms under different frequencies on the phase lead compensator, an overall system delay time can be configured. Results showed as the respiratory frequency increased, variable value ``a'' and the subsequent gain ``k'' in the controller becomes larger. Moreover, value ``a'' and ``k'' increased as the system delay time increased when the respiratory frequency was fixed. The relationship of value ``a'' and ``k'' to the respiratory frequency can be obtained by using the curve fitting method to compensate for the respiratory motion for tumor localization. Through the comparison of the uncompensated signal and the compensated signal performed by the auto tumor localization system on the simulated respiratory signal, the feasibility of using ultrasound image analysis technology combined with the

  5. Self-esteem of raped women Autoestima de las mujeres que sufrieron violencias Auto-estima de mulheres que sofreram violência

    Directory of Open Access Journals (Sweden)

    Lucila Amaral Carneiro Vianna

    2006-10-01

    Full Text Available This qualitative study shows the results of workshops held with health workers and public health users (raped women, aimed at raising these women's self-esteem and creating awareness among health workers who attend them. Neuro-Linguistic Programming techniques were used to bring back life experiences, which contributed to a re-reading and to minimize causal factors of low self-esteem. Themes like repugnance, fear and the fruit of rape; image and place; death; revenge; support and solidarity; domestic violence and bad care delivery to victims were addressed during the meetings. The stories were transcribed and analyzed, preserving content fidelity. Experiences lived at home and with loved and admired people, and mainly experiences resulting from the rape were responsible for the low self-esteem. The evaluations indicated the workshops as an opportunity to reflect, to return to normal life and to reconstruct self-esteem, for the raped women as well for the health workers who deliver care to them.Este estudio cualitativo muestra resultados de oficinas de autoestima realizadas con usuarias (mujeres que sufrieron violencia sexual y profesionales de instituciones de salud, con objeto de elevar la autoestima de esas mujeres y sensibilizar los profesionales que las asisten. Con las técnicas de la Programación Neurolinguística, surgieron experiencias vividas, favoreciendo nueva lectura y minimización de los factores causales de la baja autoestima. En los encuentros, fueron tratados temas como: asco, miedo y el fruto de la violación; imagen y local; muerte; venganza; apoyo y solidariedad; violación domestica y la mala atención a las victimas. Las historias fueron copiadas y analizadas, manteniendo la fidelidad del contenido. La responsabilidad por este problema de baja autoestima vino de experiencias negativas vividas en el hogar y con personas de nuestro circulo de afecto e admiración, principalmente las que surgieron con la violación. Las

  6. An Evaluation of a Biological Slide-Tutorial Program.

    Science.gov (United States)

    Chan, Gordon L.

    Described is an auto-tutorial slide program for zoology students. A self-paced system was devised for observing the subject matter covered in the twelve study units of a zoology course. The post-testing evaluation revealed that students with lower grade point averages achieved scores comparable with students of higher grade point averages.…

  7. Relevance of Flow Cytometric Auto-Crossmatch to the Post-transplant Course of Kidney Transplant Recipients.

    Science.gov (United States)

    Demir, E; Yeğit, O; Erol, A; Akgül, S U; Çalışkan, B; Bayraktar, A; Çalışkan, Y; Türkmen, A; Savran, F O; Sever, M S

    2017-04-01

    The crossmatch test is essential prior to kidney transplantation (tx) to confirm compatibility between the donor and the recipient. However, its results can be misleading due to "undetectable antibodies" in the recipient's serum. To establish if undetectable autoantibodies are responsible for a positive result, an auto-crossmatch test can be performed. In this study, we aim to determine the long-term prognostic value of auto-flow cytometric auto-crossmatch (FCXM) test on kidney survival in kidney tx recipients. The primary outcome variable was reduced renal function. Secondary endpoints were incidence of biopsy-confirmed chronic antibody-mediated rejection (CAMR) and recurrent glomerulonephritis (GN). There were no differences regarding initial serum creatinine levels between the study and control groups (P = .441). Patients who had positive auto-B FCXM had a significantly reduced renal function compared with the control group (P = .016). Four patients developed biopsy-confirmed CAMR in the study group and 1 patient in the control group (P = .047). Five patients had biopsy-confirmed recurrent GN in the GN study group, and only 1 patient had recurrent GN in the GN control group (P = .026). Kidney transplant recipients with positive auto-FCXM test had significantly reduced renal function and a higher incidence of recurrent GN and CAMR compared with the control group. The findings of this study suggest a potential role of auto-antibody causing positive auto-FCXM test result, meanwhile increasing the risk of CAMR, recurrent GN, and new-onset diabetes after tx. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Auto Safety

    Science.gov (United States)

    ... to Talk to Your Child About the News Gun Safety Too Late for the Flu Vaccine? Eating ... many local health departments, public safety groups, hospitals, law enforcement agencies, and fire departments have technicians or ...

  9. Ettevaatust, auto!

    Index Scriptorium Estoniae

    2008-01-01

    Väljavõte käibemaksuseaduse muutmise seaduse seletuskirjast. Lisatud: ettevõtte sõiduauto ja kaubiku omatarbe maksustamise näited. Lisatud kirjavahetus: EML selgitustaotlus Rahandusministeeriumile ; Varrak, Tea. Rahandusministeeriumi vastus selgitustaotlusele ; Lehis, Lasse. Rahandusministeerium plaanib unemaksu. - Vt.: http://www.maksumaksjad.ee/modules/smartsection/item.php?itemid=577.

  10. Effect of missing values in estimation of mean of auto-correlated measurement series.

    Science.gov (United States)

    Paakkunainen, Maaret; Kilpeläinen, Jarmo; Reinikainen, Satu-Pia; Minkkinen, Pentti

    2007-07-09

    Sampling and uncertainty of sampling are important tasks, when industrial processes are monitored. Missing values and unequal sources can cause problems in almost all industrial fields. One major problem is that during weekends samples may not be collected. On the other hand a composite sample may be collected during weekend. These systematically occurring missing values (gaps) will have an effect on the uncertainties of the measurements. Another type of missing values is random missing values. These random gaps are caused, for example, by instrument failures. Pierre Gy's sampling theory includes tools to evaluate all error components that are involved in sampling of heterogeneous materials. Variograms, introduced by Gy's sampling theory, have been developed to estimate the uncertainty of auto-correlated process measurements. Variographic experiments are utilized for estimating the variance for different sample selection strategies. The different sample selection strategies are random sampling, stratified random sampling and systematic sampling. In this paper both systematic and random gaps were estimated by using simulations and real process data. These process data were taken from bark boilers of pulp and paper mills (combustion processes). When systematic gaps were examined a linear interpolation was utilized. Also cases introducing composite sampling were studied. Aims of this paper are: (1) how reliable the variogram is to estimate the process variogram calculated from data with systematic gaps, (2) how the uncertainty of missing gap can be estimated in reporting time-averages of auto-correlated time series measurements. The results show that when systematic gaps were filled by linear interpolation only minor changes in the values of variogram were observed. The differences between the variograms were constantly smallest with composite samples. While estimating the effect of random gaps, the results show that for the non-periodic processes the stratified

  11. Origin of Magnetization Auto-Oscillations in Constriction-Based Spin Hall Nano-Oscillators

    Science.gov (United States)

    Dvornik, Mykola; Awad, Ahmad A.; Åkerman, Johan

    2018-01-01

    We use micromagnetic simulations to map out and compare the linear and auto-oscillating modes in constriction-based spin Hall nano-oscillators as a function of the applied magnetic field with a varying magnitude and out-of-plane angle. We demonstrate that, for all possible applied field configurations, the auto-oscillations emerge from the localized linear modes of the constriction. For field directions tending towards the plane, these modes are of the so-called edge type, i.e., localized at the opposite edges of the constriction. By contrast, when the magnetization direction approaches the film normal, the modes transform to the so-called bulk type, i.e., localized inside the constriction with substantially increased precession volume, consistent with the redistribution of the magnetic charges from the edges to the top and bottom surfaces of the constriction. In general, the threshold current of the corresponding auto-oscillations increases with the applied field strength and decreases with its out-of-plane angle, consistent with the behavior of the internal field and in good agreement with a macrospin model. A quantitative agreement is then achieved by taking into account the strongly nonuniform character of the system via a mean-field approximation. Both the Oersted (Oe) field and the spin-transfer torque from the drive current increase the localization and decrease the frequency of the observed mode. Furthermore, the antisymmetric Oe field breaks the lateral symmetry, favoring the localized mode at one of the two constriction edges, particularly for large out-of-plane field angles where the threshold current is significantly increased and the edge demagnetization is suppressed.

  12. Auto-Gopher: a wire-line rotary-hammer ultrasonic drill

    Science.gov (United States)

    Badescu, Mircea; Sherrit, Stewart; Bao, Xiaoqi; Bar-Cohen, Yoseph; Chen, Beck

    2011-04-01

    Developing technologies that would enable NASA to sample rock, soil, and ice by coring, drilling or abrading at a significant depth is of great importance for a large number of in-situ exploration missions as well as for earth applications. Proven techniques to sample Mars subsurface will be critical for future NASA astrobiology missions that will search for records of past and present life on the planet, as well as the search of water and other resources. A deep corer, called Auto-Gopher, is currently being developed as a joint effort of the JPL's NDEAA laboratory and Honeybee Robotics Corp. The Auto-Gopher is a wire-line rotary- hammer drill that combines rock breaking by hammering using an ultrasonic actuator and cuttings removal by rotating a fluted bit. The hammering mechanism is based on the Ultrasonic/Sonic Drill/Corer (USDC) that has been developed as an adaptable tool for many of drilling and coring applications. The USDC uses an intermediate free-flying mass to transform the high frequency vibrations of the horn tip into a sonic hammering of a drill bit. The USDC concept was used in a previous task to develop an Ultrasonic/Sonic Ice Gopher. The lessons learned from testing the ice gopher were implemented into the design of the Auto-Gopher by inducing a rotary motion onto the fluted coring bit. A wire-line version of such a system would allow penetration of significant depth without a large increase in mass. A laboratory version of the corer was developed in the NDEAA lab to determine the design and drive parameters of the integrated system. The design configuration lab version of the design and fabrication and preliminary testing results are presented in this paper.

  13. Efficiency and cost analysis of cell saver auto transfusion system in total knee arthroplasty.

    Science.gov (United States)

    Bilgili, Mustafa Gökhan; Erçin, Ersin; Peker, Gökhan; Kural, Cemal; Başaran, Serdar Hakan; Duramaz, Altuğ; Avkan, Cevdet

    2014-06-01

    Blood loss and replacement is still a controversial issue in major orthopaedic surgery. Allogenic blood transfusion may cause legal problems and concerns regarding the transmission of transfusion-related diseases. Cellsaver Systems (CSS) were developed as an alternative to allogenic transfusion but CSS transfusion may cause coagulation, infection and haemodynamic instability. Our aim was to analyse the efficiency and cost analysis of a cell saver auto-transfusion system in the total knee arthroplasty procedure. Retrospective comparative study. Those patients who were operated on by unilateral, cemented total knee arthroplasty (TKA) were retrospectively evaluated. Group 1 included 37 patients who were treated using the cell saver system, and Group 2 involved 39 patients who were treated by allogenic blood transfusion. The groups were compared in terms of preoperative haemoglobin and haematocrit levels, blood loss and transfusion amount, whether allogenic transfusion was made, degree of deformity, body mass index and cost. No significant results could be obtained in the statistical comparisons made in terms of the demographic properties, deformity properties, preoperative laboratory values, transfusion amount and length of hospital stay of the groups. Average blood loss was calculated to be less in Group 1 (ptransfusion and costs more. Therefore, the routine usage of the auto-transfusion systems is a controversial issue. Cell saver system usage does not affect allogenic blood transfusion incidence or allogenic blood transfusion volume. It was found that preoperative haemoglobin and body mass index rates may affect allogenic blood transfusion. Therefore, it is foreseen that auto-transfusion systems could be useful in patients with low haemoglobin level and body mass index.

  14. In silico design and performance of peptide microarrays for breast cancer tumour-auto-antibody testing

    Directory of Open Access Journals (Sweden)

    Andreas Weinhäusel

    2012-06-01

    Full Text Available The simplicity and potential of minimally invasive testing using sera from patients makes auto-antibody based biomarkers a very promising tool for use in cancer diagnostics. Protein microarrays have been used for the identification of such auto-antibody signatures. Because high throughput protein expression and purification is laborious, synthetic peptides might be a good alternative for microarray generation and multiplexed analyses. In this study, we designed 1185 antigenic peptides, deduced from proteins expressed by 642 cDNA expression clones found to be sero-reactive in both breast tumour patients and controls. The sero-reactive proteins and the corresponding peptides were used for the production of protein and peptide microarrays. Serum samples from females with benign and malignant breast tumours and healthy control sera (n=16 per group were then analysed. Correct classification of the serum samples on peptide microarrays were 78% for discrimination of ‘malignant versus healthy controls’, 72% for ‘benign versus malignant’ and 94% for ‘benign versus controls’. On protein arrays, correct classification for these contrasts was 69%, 59% and 59%, respectively. The over-representation analysis of the classifiers derived from class prediction showed enrichment of genes associated with ribosomes, spliceosomes, endocytosis and the pentose phosphate pathway. Sequence analyses of the peptides with the highest sero-reactivity demonstrated enrichment of the zinc-finger domain. Peptides’ sero-reactivities were found negatively correlated with hydrophobicity and positively correlated with positive charge, high inter-residue protein contact energies and a secondary structure propensity bias. This study hints at the possibility of using in silico designed antigenic peptide microarrays as an alternative to protein microarrays for the improvement of tumour auto-antibody based diagnostics.

  15. An auto-balancer device for high spin-drying frequencies (LoWash Project

    Directory of Open Access Journals (Sweden)

    Clerc Christian

    2015-01-01

    Full Text Available Auto-balancing or active control balancing can be efficient solutions for high speed rotors with changing out-of-balance loads like washing machines in spin-drying mode. In the LoWash EU project, Vibratec is in charge to design, to build and to validate a balancing system for reducing the vibrations at high spin-drying speeds. The system is based on two trolleys rolling in a ring linked to the drum. The trolley shape allows a ring cross section optimization and they are equipped with a mechanism for escaping the disadvantage encountered at low speeds by similar devices. Analytical and multi-body models are first made for understanding the mechanisms, highlighting the driving parameters and drawing the final design of a first prototype which is inserted in a washing machine drum. Different tests are carried out for different initial unbalances and different rotation speeds: the residual unbalance is measured by means of a set of accelerometers mounted on the tub, while the mobile masses behaviour is observed by means of a large aperture swift camera. The test results highlight the auto-balancer high efficiency but also the sensitivity to geometrical defects which should be corrected in the next systems. According the theory, the balancing is efficient when the rotation frequency is significantly greater than the hanging frequencies. The multi-body model relevance is also demonstrated. A washer-dryer prototype including an auto-balancer second prototype and two other innovations, regarding thermal exchange efficiency and drum insulation, will be tested in operating conditions.

  16. Auto-Gopher: A Wire-Line Rotary-Hammer Ultrasonic Drill

    Science.gov (United States)

    Badescu, Mircea; Sherrit, Stewart; Bao, Xiaogi; Bar-Cohen, Yoseph; Chen, Beck

    2011-01-01

    Developing technologies that would enable NASA to sample rock, soil, and ice by coring, drilling or abrading at a significant depth is of great importance for a large number of in-situ exploration missions as well as for earth applications. Proven techniques to sample Mars subsurface will be critical for future NASA astrobiology missions that will search for records of past and present life on the planet, as well as, the search for water and other resources. A deep corer, called Auto-Gopher, is currently being developed as a joint effort of the JPL's NDEAA laboratory and Honeybee Robotics Corp. The Auto-Gopher is a wire-line rotary-hammer drill that combines rock breaking by hammering using an ultrasonic actuator and cuttings removal by rotating a fluted bit. The hammering mechanism is based on the Ultrasonic/Sonic Drill/Corer (USDC) that has been developed as an adaptable tool for many of drilling and coring applications. The USDC uses an intermediate free-flying mass to transform the high frequency vibrations of the horn tip into a sonic hammering of a drill bit. The USDC concept was used in a previous task to develop an Ultrasonic/Sonic Ice Gopher. The lessons learned from testing the ice gopher were implemented into the design of the Auto-Gopher by inducing a rotary motion onto the fluted coring bit. A wire-line version of such a system would allow penetration of significant depth without a large increase in mass. A laboratory version of the corer was developed in the NDEAA lab to determine the design and drive parameters of the integrated system. The design configuration lab version of the design and fabrication and preliminary testing results are presented in this paper

  17. Homologous Hevea brasiliensis REF (Hevb1) and SRPP (Hevb3) present different auto-assembling.

    Science.gov (United States)

    Berthelot, Karine; Lecomte, Sophie; Estevez, Yannick; Coulary-Salin, Bénédicte; Peruch, Frédéric

    2014-02-01

    HbREF and HbSRPP are two Hevea brasiliensis proteins present on rubber particles, and probably involved in the coagulation of latex. Their function is unclear, but we previously discovered that REF had amyloid properties, which could be of particular interest during the coagulation process. First, we confirmed that REF and SRPP, homologous and principal proteins in hevea latex, are not glycoproteins. In this work, we investigated various aspects of protein interactions: aggregation, auto-assembling, yeast and erythrocyte agglutination, co-interactions by various biochemical (PAGE, spectroscopy, microscopy), biophysical (DLS, ellipsometry) and structural (TEM, ATR-FTIR, PM-IRRAS) approaches. We demonstrated that both proteins are auto-assembling into different aggregative states: REF polymerizes as an amyloid rich in β-sheets and forms quickly large aggregates (>μm), whereas SRPP auto-assembles in solution into stable nanomultimers of a more globular nature. Both proteins are however able to interact together, and SRPP may inhibit the amyloidogenesis of REF. REF is also able to interact with the membranes of yeasts and erythrocytes, leading to their agglutination. In addition, we also showed that both REF and SRPP did not have antimicrobial activity, whereas their activity on membranes has been clearly evidenced. We may suspect that these aggregative properties, even though they are clearly different, may occur during coagulation, when the membrane is destabilized. The interaction of proteins with membranes could help in the colloidal stability of latex, whereas the protein-protein interactions would contribute to the coagulation process, by bringing rubber particles together or eventually disrupting the particle monomembranes. Copyright © 2013 Elsevier B.V. All rights reserved.

  18. Genetic and phenotypic selection affect natural (auto-) antibody reactivity of chickens.

    Science.gov (United States)

    de Jong, Britt G; Lammers, Aart; Oberendorf, Leonora A A; Nieuwland, Mike G B; Savelkoul, Huub F J; Parmentier, Henk K

    2013-01-01

    Specificity, antibody isotype distribution and levels of natural antibodies (NAb) may be potential informative parameters for immune mediated natural disease resistance, immune modulation, and maintenance of physiological homeostasis. A large proportion of mammalian NAb have affinity for or are directed against self-antigens; so called natural auto antibodies (N(A)Ab). In the present study we showed the presence and typed levels and isotypes (total immunoglobulins, IgG and IgM) of N(A)Ab in plasma binding the 'auto-antigen' complex chicken liver cell lysate (CLL) of one-year old chickens from different genotype and phenotype backgrounds by ELISA and quantitative Western blotting. Higher levels of N(A)Ab binding CLL were found in plasma from chickens genetically selected for high specific antibody responses. In all birds, extensive staining patterns of plasma antibodies binding CLL were found for all isotypes, with IgG binding the highest number of CLL antigens and also showing the highest variation in staining patterns between individuals. Patterns of IgM antibodies binding CLL appeared to be more similar in all lines. Significant differences of binding patterns of N(A)Ab (antigen fragments of CLL and staining intensity) were detected between the different chicken lines, and lines could be clustered on the basis of their auto-antibody profile. In addition, also individual differences within lines were found. The present results indicate that analysis of the levels and the N(A)Ab repertoire of poultry like in mammals could provide a new way of distinguishing differences of immune competence and immune maturation between individuals, and could provide tools to select birds for health traits, or optimize hygiene and husbandry procedures.

  19. Genetic and phenotypic selection affect natural (auto- antibody reactivity of chickens.

    Directory of Open Access Journals (Sweden)

    Britt G de Jong

    Full Text Available Specificity, antibody isotype distribution and levels of natural antibodies (NAb may be potential informative parameters for immune mediated natural disease resistance, immune modulation, and maintenance of physiological homeostasis. A large proportion of mammalian NAb have affinity for or are directed against self-antigens; so called natural auto antibodies (N(AAb. In the present study we showed the presence and typed levels and isotypes (total immunoglobulins, IgG and IgM of N(AAb in plasma binding the 'auto-antigen' complex chicken liver cell lysate (CLL of one-year old chickens from different genotype and phenotype backgrounds by ELISA and quantitative Western blotting. Higher levels of N(AAb binding CLL were found in plasma from chickens genetically selected for high specific antibody responses. In all birds, extensive staining patterns of plasma antibodies binding CLL were found for all isotypes, with IgG binding the highest number of CLL antigens and also showing the highest variation in staining patterns between individuals. Patterns of IgM antibodies binding CLL appeared to be more similar in all lines. Significant differences of binding patterns of N(AAb (antigen fragments of CLL and staining intensity were detected between the different chicken lines, and lines could be clustered on the basis of their auto-antibody profile. In addition, also individual differences within lines were found. The present results indicate that analysis of the levels and the N(AAb repertoire of poultry like in mammals could provide a new way of distinguishing differences of immune competence and immune maturation between individuals, and could provide tools to select birds for health traits, or optimize hygiene and husbandry procedures.

  20. Estereotipos de género 2.0: Auto-representaciones de adolescentes en Facebook

    Directory of Open Access Journals (Sweden)

    2016-07-01

    Full Text Available Chicas y chicos adolescentes hacen un uso diferente de las redes sociales online, y las chicas presentan un mayor riesgo de verse perjudicadas por un uso no adaptativo. El objetivo de este estudio era investigar en qué medida los adolescentes se presentan en términos de estereotipos de género en sus perfiles de Facebook. Los participantes, 623 usuarios de Facebook de ambos sexos, contestaron el Bem Sex Role Inventory (BSRI y el Personal Well-being Index (PWI. En la primera fase, respondieron sobre cómo ven a un adulto típico en términos de estereotipos de género. En la segunda fase, la mitad de ellos contestó el BSRI en relación a cómo se ven a sí mismos, y la otra mitad cómo se presentan en Facebook. Los resultados muestran que los adolescentes se consideran más sexualmente indiferenciados que un adulto típico de su mismo sexo, tanto en su auto-percepción como en su presentación en Facebook. Se confirma que el bienestar psicológico de las chicas baja considerablemente con la edad, y que está asociado a un mayor grado de masculinidad. Se concluye que los adolescentes producen representaciones verdaderas en sus perfiles de Facebook, y que existe una tendencia hacia una auto-concepción y auto-presentación más sexualmente indiferenciada con una leve preferencia por rasgos masculinos, tanto en chicos como en chicas; además, la masculinidad está asociada a un mayor grado de bienestar psicológico.