Enhanced Geothermal Systems (EGS) R&D Program

Energy Technology Data Exchange (ETDEWEB)

Entingh, Daniel J.

1999-08-18

The purpose of this workshop was to develop technical background facts necessary for planning continued research and development of Enhanced Geothermal Systems (EGS). EGS are geothermal reservoirs that require improvement of their permeability or fluid contents in order to achieve economic energy production. The initial focus of this R&D program is devising and testing means to extract additional economic energy from marginal volumes of hydrothermal reservoirs that are already producing commercial energy. By mid-1999, the evolution of the EGS R&D Program, begun in FY 1988 by the U.S. Department of Energy (DOE), reached the stage where considerable expertise had to be brought to bear on what technical goals should be pursued. The main purpose of this Workshop was to do that. The Workshop was sponsored by the Office of Geothermal Technologies of the Department of Energy. Its purpose and timing were endorsed by the EGS National Coordinating Committee, through which the EGS R&D Program receives guidance from members of the U.S. geothermal industry. Section 1.0 of this report documents the EGS R&D Program Review Session. There, managers and researchers described the goals and activities of the program. Recent experience with injection at The Geysers and analysis of downhole conditions at Dixie Valley highlighted this session. Section 2.0 contains a number of technical presentations that were invited or volunteered to illuminate important technical and economic facts and opportunities for research. The emphasis here was on fi.acture creation, detection, and analysis. Section 3.0 documents the initial general discussions of the participants. Important topics that emerged were: Specificity of defined projects, Optimizing cost effectiveness, Main technical areas to work on, Overlaps between EGS and Reservoir Technology R&D areas, Relationship of microseismic events to hydraulic fractures, and Defining criteria for prioritizing research thrusts. Sections 4.0 and 5.0 report

Interactive editing program using display

International Nuclear Information System (INIS)

Lang, I.; Ehsenski, J.; Namsraj, Yu.; Fefilov, B.V.

1976-01-01

A general description is given as well as principal functions are considered of 'DOSE' interactive editor program with a display involved. The program has been elaborated for TRA/1-1001 computer. This program enables one to edit and correct texts in algorithmical languages on a raster display screen as well as to provide perforated tapes for their further usage. 'DOSE' program is regarded as a basic program system for a set of TRA/1 and MINSK-32 computers

Beginning Programming with Java For Dummies

CERN Document Server

Burd, Barry

2012-01-01

One of the most popular beginning programming books, now fully updated Java is a popular language for beginning programmers, and earlier editions of this fun and friendly guide have helped thousands get started. Now fully revised to cover recent updates for Java 7.0, Beginning Programming with Java For Dummies, 3rd Edition is certain to put more first-time programmers and Java beginners on the road to Java mastery.Explores what goes into creating a program, putting the pieces together, dealing with standard programming challenges, debugging, and making the program work Offers new options for

Psychometric properties and validation of Portuguese version of Ages & Stages Questionnaires (3rd edition): 9, 18 and 30 Questionnaires.

Science.gov (United States)

Lopes, Sónia; Graça, Patrícia; Teixeira, Salete; Serrano, Ana Maria; Squires, Jane

2015-09-01

The essential underlying foundations of Early Intervention (EI), in which parents/family play a critical role in their child's development, leads us to conclude that their contribution assessing early detection of problems is fundamental. The Ages & Stages Questionnaires (ASQ) is a standardized screening instrument that has been successfully studied in different countries and cultures. Translate and study the psychometrics proprieties of the Portuguese version of the 9, 18 and 30month questionnaires of the Ages and Stages Questionnaires, 3rd edition (ASQ-3). Cross-sectional study. Validity and reliability were studied in a sample of 234 parents of children within 9, 18 and 30months. The results indicated that the questionnaires had good internal consistency, strong agreement between observers and between observations with two weeks interval, and strong Pearson product-moment correlation coefficients between the overall and the total for each domain. The cutoff points (i.e. 2 standard deviations below the mean domain score), that identifies children who should receive further referral for more comprehensive assessment, were close to those determined in the original ASQ-3 psychometric studies. Cronbach's alpha ranging from .42 to .70 and Pearson's r values varies from .22 to .60. Although some weaknesses were noted in psychometric qualities analysis, it can be concluded that the ASQ-PT of 9, 18 and 30months of age fulfills the requirements of a screening tool validated for the Portuguese population. To allow the early identification of children with developmental problems. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

MANAJEMEN EDITING POST PRODUCTION PROGRAM CURRENT AFFAIR DI TVONE

Directory of Open Access Journals (Sweden)

Ridho Azlam Ambo Asse

2016-11-01

Full Text Available Management is the art of completing the work through others. In an organization there are various components that are structured and coordinated in the movement toward shared vision and mission. Management is looking for that component to move under coordination, pressure, and problems that hit. Editing management, especially for the current affair type program, has a special purpose. Not just the speed of productivity that is based on the ability of individual editors. This research is done to know the process of stage editor in work. The process of managing files, data management, human resources, tools, facilities, scheduling, until the pattern of editing stage in one of the national media industry. This study concludes that the current affair program management editing system based on the concept of planning, organizing, implementation, supervision, and productivity management is done by Top Down method from top to bottom in the management of currenf affair tvOne editing program. What gets from above during a pre-production meeting of a program. Then coordinate with the supervisor and then delegate down to be implemented according to the agreed plan and in accordance with the duties and functions of both the production team and the editor.   Manajemen merupakan seni menyelesaikan pekerjaan melalui orang lain. Dalam sebuah organisasi terdapat berbagai macam komponen yang terstruktur dan terkordinasi dalam gerakan menuju visi dan misi bersama. Manajemen ialah mencari agar komponen tersebut dapat bergerak dibawah koordinasi, tekanan, dan masalah yang menerpa. Manajemen editing khususnya untuk program berjenis current affair, memiliki tujuan khusus. Tidak sekedar kecepatan produktifitas yang didasarkan pada kemampuan individu editor. Penelitian yang dilakukan ini untuk mengetahui proses tahapan editor dalam bekerja. Proses mengelola file, pengelolaan data, sumber daya manusia, alat, fasilitas, penjadwalan, hingga pola tahapan editing pada salah

A procedure for safety assessment of components with cracks - Handbook. 3rd revised edition

Energy Technology Data Exchange (ETDEWEB)

Andersson, P.; Bergman, M.; Brickstad, B.; Dahlberg, L.; Nilsson, F.; Sattari-Far, I. [SAQ Kontroll AB, Stockholm (Sweden)

1999-12-01

given objectives, the handbook contains solutions for the stress intensity factor and the limit load for a number of crack geometries of importance for applications. It also contains rules for defect characterization, recommendations for estimation of residual stresses, material data for nuclear applications and a safety evaluation system. To ensure conservatism, the procedure with the given solutions of the stress intensity factor and the limit load has been validated. Predictions of the procedure were compared with the actual outcome of full scale experiments reported in the literature. The first edition of the handbook was released in 1990 and the second in 1991. This third edition has been extensively revised. A new safety evaluation system has been introduced. The conservatism in the method for assessment of secondary stresses has been reduced. The solutions for the stress intensity factor and the limit load, the recommendations for estimation of residual stresses and the given material data for nuclear applications have been updated. A modern Windows based PC-program SACC has been developed which can perform the assessments described in this handbook including calculation of crack growth due to stress corrosion and fatigue. The program also has an option which enables assessment of cracks according to the 1995 edition of the ASME Boiler and Pressure Vessel Code, Section XI. Appendices A, C and H for assessment of cracks in ferritic pressure vessels, austenitic piping and ferritic piping, respectively.

A procedure for safety assessment of components with cracks - Handbook. 3rd revised edition

International Nuclear Information System (INIS)

Andersson, P.; Bergman, M.; Brickstad, B.; Dahlberg, L.; Nilsson, F.; Sattari-Far, I.

1999-12-01

, the handbook contains solutions for the stress intensity factor and the limit load for a number of crack geometries of importance for applications. It also contains rules for defect characterization, recommendations for estimation of residual stresses, material data for nuclear applications and a safety evaluation system. To ensure conservatism, the procedure with the given solutions of the stress intensity factor and the limit load has been validated. Predictions of the procedure were compared with the actual outcome of full scale experiments reported in the literature. The first edition of the handbook was released in 1990 and the second in 1991. This third edition has been extensively revised. A new safety evaluation system has been introduced. The conservatism in the method for assessment of secondary stresses has been reduced. The solutions for the stress intensity factor and the limit load, the recommendations for estimation of residual stresses and the given material data for nuclear applications have been updated. A modern Windows based PC-program SACC has been developed which can perform the assessments described in this handbook including calculation of crack growth due to stress corrosion and fatigue. The program also has an option which enables assessment of cracks according to the 1995 edition of the ASME Boiler and Pressure Vessel Code, Section XI. Appendices A, C and H for assessment of cracks in ferritic pressure vessels, austenitic piping and ferritic piping, respectively

Conference proceedings of the 2nd and 3rd Regional Innovation & Entrepreneurship Conference : at Saxion University of applied sciences

NARCIS (Netherlands)

Bazen, J.J. (Jacques); Hammer, M.H.M. (Matthijs)

2016-01-01

DOI:https://doi.org/10.14261/postit/F20ECDBA-3106-4133-9EE0714DBAA65B51 In 2015 and 2016, Saxion University of Applied Sciences organized the 2nd and 3rd edition of the Regional Innovation and Entrepreneurship Conference (RIEC). The book that is in front of you now is the result of these two

Handbook on process and chemistry of nuclear fuel reprocessing. 3rd edition

International Nuclear Information System (INIS)

2015-03-01

The fundamental data on spent nuclear fuel reprocessing and related chemistry was collected and summarized as a new edition of 'Handbook on Process and Chemistry of Nuclear Fuel Reprocessing'. The purpose of this handbook is contribution to development of the fuel reprocessing and fuel cycle technology for uranium fuel and mixed oxide fuel utilization. Contents in this book was discussed and reviewed by specialists of science and technology on fuel reprocessing in Japan. (author)

Microstructure Modeling of 3rd Generation Disk Alloys

Science.gov (United States)

Jou, Herng-Jeng

2010-01-01

The objective of this program is to model, validate, and predict the precipitation microstructure evolution, using PrecipiCalc (QuesTek Innovations LLC) software, for 3rd generation Ni-based gas turbine disc superalloys during processing and service, with a set of logical and consistent experiments and characterizations. Furthermore, within this program, the originally research-oriented microstructure simulation tool will be further improved and implemented to be a useful and user-friendly engineering tool. In this report, the key accomplishment achieved during the second year (2008) of the program is summarized. The activities of this year include final selection of multicomponent thermodynamics and mobility databases, precipitate surface energy determination from nucleation experiment, multiscale comparison of predicted versus measured intragrain precipitation microstructure in quench samples showing good agreement, isothermal coarsening experiment and interaction of grain boundary and intergrain precipitates, primary microstructure of subsolvus treatment, and finally the software implementation plan for the third year of the project. In the following year, the calibrated models and simulation tools will be validated against an independently developed experimental data set, with actual disc heat treatment process conditions. Furthermore, software integration and implementation will be developed to provide material engineers valuable information in order to optimize the processing of the 3rd generation gas turbine disc alloys.

Overview of the NASA balloon R&D program

Science.gov (United States)

Smith, I. Steve, Jr.

1994-01-01

The catastrophic balloon failure during the first half of the 1980's identified the need for a comprehensive and continuing balloon research and development (R&D) commitment by NASA. Technical understanding was lacking in many of the disciplines and processes associated with scientific ballooning. A comprehensive balloon R&D plan was developed in 1986 and implemented in 1987. The objectives were to develop the understanding of balloon system performance, limitations, and failure mechanisms. The program consisted of five major technical areas: structures, performance and analysis, materials, chemistry and processing, and quality control. Research activitites have been conducted at NASA/Goddard Space Flight Center (GSFC)-Wallops Flight Facility (WFF), other NASA centers and government facilities, universities, and the balloon manufacturers. Several new and increased capabilities and resources have resulted from this activity. The findings, capabilities, and plan of the balloon R&D program are presented.

Methodological proposal for the volumetric study of archaeological ceramics through 3D edition free-software programs: the case of the celtiberians cemeteries of the meseta

Directory of Open Access Journals (Sweden)

Álvaro Sánchez Climent

2014-10-01

Full Text Available Nowadays the free-software programs have been converted into the ideal tools for the archaeological researches, reaching the same level as other commercial programs. For that reason, the 3D modeling tool Blender has reached in the last years a great popularity offering similar characteristics like other commercial 3D editing programs such as 3D Studio Max or AutoCAD. Recently, it has been developed the necessary script for the volumetric calculations of three-dimnesional objects, offering great possibilities to calculate the volume of the archaeological ceramics. In this paper, we present a methodological approach for the volumetric studies with Blender and a study case of funerary urns from several celtiberians cemeteries of the Spanish Meseta. The goal is to demonstrate the great possibilities that the 3D editing free-software tools have in the volumetric studies at the present time.

An introduction to programming using visual basic 2012(wvisual studio 2012 express edition dvd) (9th edition)

CERN Document Server

Schneider, David I.

2013-01-01

An Introduction to Programming Using Visual Basic 2012, Ninth Edition —consistently praised by both students and instructors — is designed for readers with no prior computer programming experience. Now updated for Visual Basic 2012, Schneider focuses on teaching problem-solving skills and sustainable programming skills. A broad range of real-world examples, section-ending exercises, case studies, and programming projects gives readers more hands-on experience than any other Visual Basic book on the market. NEW! This edition is available with MyProgrammingLab, an innovative online homework and assessment tool. Through the power of practice and immediate personalized feedback, MyProgrammingLab helps students fully grasp the logic, semantics, and syntax of programming. Note: If you are purchasing the standalone text or electronic version, MyProgrammingLab does not come automatically packaged with the text. To purchase MyProgrammingLab, please visit: myprogramminglab.com or you can purchase a...

Evaluation of long-term RD and D programs in the presence of market uncertainties

International Nuclear Information System (INIS)

Hazelrigg, G.A. Jr.

1982-01-01

Long-term research, development, and demonstration (RD and D) programs such as fusion research can span several decades, progressing through a number of discrete RD and D phases. Pursuit of a technology such as fusion does not mean commitment to the entire RD and D program, but only to the next phase of RD and D. The evaluation of a long-term RD and D program must account for the decision process to continue, modify, or discontinue the program upon completion of each RD and D phase, the technological uncertainties inherent in a long-term RD and D program, and the uncertainty inherent in the future marketplace for the technology if and when it becomes available. Presented here is a methodology that does this. An application of the methodology to fusion research is included. The example application shows that the perceived economic value of fusion research is strongly dependent on market uncertainty, with increasing market uncertainty yielding greatly increased perceived value to the research effort. 7 references, 8 figures, 2 tables

2015 Edition Health Information Technology (Health IT) Certification Criteria, 2015 Edition Base Electronic Health Record (EHR) Definition, and ONC Health IT Certification Program Modifications. Final rule.

Science.gov (United States)

2015-10-16

This final rule finalizes a new edition of certification criteria (the 2015 Edition health IT certification criteria or "2015 Edition'') and a new 2015 Edition Base Electronic Health Record (EHR) definition, while also modifying the ONC Health IT Certification Program to make it open and accessible to more types of health IT and health IT that supports various care and practice settings. The 2015 Edition establishes the capabilities and specifies the related standards and implementation specifications that Certified Electronic Health Record Technology (CEHRT) would need to include to, at a minimum, support the achievement of meaningful use by eligible professionals (EPs), eligible hospitals, and critical access hospitals (CAHs) under the Medicare and Medicaid EHR Incentive Programs (EHR Incentive Programs) when such edition is required for use under these programs.

Editing modifies the GABA(A) receptor subunit alpha3

DEFF Research Database (Denmark)

Ohlson, Johan; Pedersen, Jakob Skou; Haussler, David

2007-01-01

Adenosine to inosine (A-to-I) pre-mRNA editing by the ADAR enzyme family has the potential to increase the variety of the proteome. This editing by adenosine deamination is essential in mammals for a functional brain. To detect novel substrates for A-to-I editing we have used an experimental method...... to find selectively edited sites and combined it with bioinformatic techniques that find stem-loop structures suitable for editing. We present here the first verified editing candidate detected by this screening procedure. We show that Gabra-3, which codes for the alpha3 subunit of the GABA(A) receptor......, is a substrate for editing by both ADAR1 and ADAR2. Editing of the Gabra-3 mRNA recodes an isoleucine to a methionine. The extent of editing is low at birth but increases with age, reaching close to 100% in the adult brain. We therefore propose that editing of the Gabra-3 mRNA is important for normal brain...

Wind Program Newsletter, May 2016 Edition

Energy Technology Data Exchange (ETDEWEB)

2016-05-01

The U.S. Department of Energy Wind Program Newsletter provides wind industry stakeholders and the public with information about the Wind Program R&D efforts funded by the Wind and Water Power Technologies Office. The newsletter comes out twice a year and is sent electronically to subscribers and distributed in hard copy to conference attendees.

3rd International Conference on Robot Intelligence Technology and Applications

CERN Document Server

Yang, Weimin; Jo, Jun; Sincak, Peter; Myung, Hyun

2015-01-01

This book covers all aspects of robot intelligence from perception at sensor level and reasoning at cognitive level to behavior planning at execution level for each low level segment of the machine. It also presents the technologies for cognitive reasoning, social interaction with humans, behavior generation, ability to cooperate with other robots, ambience awareness, and an artificial genome that can be passed on to other robots. These technologies are to materialize cognitive intelligence, social intelligence, behavioral intelligence, collective intelligence, ambient intelligence and genetic intelligence. The book aims at serving researchers and practitioners with a timely dissemination of the recent progress on robot intelligence technology and its applications, based on a collection of papers presented at the 3rd International Conference on Robot Intelligence Technology and Applications (RiTA), held in Beijing, China, November 6 - 8, 2014. For better readability, this edition has the total 74 papers group...

Universal health coverage and intersectoral action for health: key messages from Disease Control Priorities, 3rd edition.

Science.gov (United States)

Jamison, Dean T; Alwan, Ala; Mock, Charles N; Nugent, Rachel; Watkins, David; Adeyi, Olusoji; Anand, Shuchi; Atun, Rifat; Bertozzi, Stefano; Bhutta, Zulfiqar; Binagwaho, Agnes; Black, Robert; Blecher, Mark; Bloom, Barry R; Brouwer, Elizabeth; Bundy, Donald A P; Chisholm, Dan; Cieza, Alarcos; Cullen, Mark; Danforth, Kristen; de Silva, Nilanthi; Debas, Haile T; Donkor, Peter; Dua, Tarun; Fleming, Kenneth A; Gallivan, Mark; Garcia, Patricia J; Gawande, Atul; Gaziano, Thomas; Gelband, Hellen; Glass, Roger; Glassman, Amanda; Gray, Glenda; Habte, Demissie; Holmes, King K; Horton, Susan; Hutton, Guy; Jha, Prabhat; Knaul, Felicia M; Kobusingye, Olive; Krakauer, Eric L; Kruk, Margaret E; Lachmann, Peter; Laxminarayan, Ramanan; Levin, Carol; Looi, Lai Meng; Madhav, Nita; Mahmoud, Adel; Mbanya, Jean Claude; Measham, Anthony; Medina-Mora, María Elena; Medlin, Carol; Mills, Anne; Mills, Jody-Anne; Montoya, Jaime; Norheim, Ole; Olson, Zachary; Omokhodion, Folashade; Oppenheim, Ben; Ord, Toby; Patel, Vikram; Patton, George C; Peabody, John; Prabhakaran, Dorairaj; Qi, Jinyuan; Reynolds, Teri; Ruacan, Sevket; Sankaranarayanan, Rengaswamy; Sepúlveda, Jaime; Skolnik, Richard; Smith, Kirk R; Temmerman, Marleen; Tollman, Stephen; Verguet, Stéphane; Walker, Damian G; Walker, Neff; Wu, Yangfeng; Zhao, Kun

2018-03-17

The World Bank is publishing nine volumes of Disease Control Priorities, 3rd edition (DCP3) between 2015 and 2018. Volume 9, Improving Health and Reducing Poverty, summarises the main messages from all the volumes and contains cross-cutting analyses. This Review draws on all nine volumes to convey conclusions. The analysis in DCP3 is built around 21 essential packages that were developed in the nine volumes. Each essential package addresses the concerns of a major professional community (eg, child health or surgery) and contains a mix of intersectoral policies and health-sector interventions. 71 intersectoral prevention policies were identified in total, 29 of which are priorities for early introduction. Interventions within the health sector were grouped onto five platforms (population based, community level, health centre, first-level hospital, and referral hospital). DCP3 defines a model concept of essential universal health coverage (EUHC) with 218 interventions that provides a starting point for country-specific analysis of priorities. Assuming steady-state implementation by 2030, EUHC in lower-middle-income countries would reduce premature deaths by an estimated 4·2 million per year. Estimated total costs prove substantial: about 9·1% of (current) gross national income (GNI) in low-income countries and 5·2% of GNI in lower-middle-income countries. Financing provision of continuing intervention against chronic conditions accounts for about half of estimated incremental costs. For lower-middle-income countries, the mortality reduction from implementing the EUHC can only reach about half the mortality reduction in non-communicable diseases called for by the Sustainable Development Goals. Full achievement will require increased investment or sustained intersectoral action, and actions by finance ministries to tax smoking and polluting emissions and to reduce or eliminate (often large) subsidies on fossil fuels appear of central importance. DCP3 is intended to

Universal health coverage and intersectoral action for health: key messages from Disease Control Priorities, 3rd edition

Science.gov (United States)

Jamison, Dean T; Adeyi, Olusoji; Anand, Shuchi; Atun, Rifat; Bertozzi, Stefano; Bhutta, Zulfiqar; Binagwaho, Agnes; Black, Robert; Blecher, Mark; Bloom, Barry R; Brouwer, Elizabeth; Bundy, Donald A P; Chisholm, Dan; Cieza, Alarcos; Cullen, Mark; Danforth, Kristen; de Silva, Nilanthi; Debas, Haile T; Donkor, Peter; Dua, Tarun; Fleming, Kenneth A; Gallivan, Mark; Garcia, Patricia J; Gawande, Atul; Gaziano, Thomas; Gelband, Hellen; Glass, Roger; Glassman, Amanda; Gray, Glenda; Habte, Demissie; Holmes, King K; Horton, Susan; Hutton, Guy; Jha, Prabhat; Knaul, Felicia M; Kobusingye, Olive; Krakauer, Eric L; Kruk, Margaret E; Lachmann, Peter; Laxminarayan, Ramanan; Levin, Carol; Looi, Lai Meng; Madhav, Nita; Mahmoud, Adel; Mbanya, Jean Claude; Measham, Anthony; Medina-Mora, María Elena; Medlin, Carol; Mills, Anne; Mills, Jody-Anne; Montoya, Jaime; Norheim, Ole; Olson, Zachary; Omokhodion, Folashade; Oppenheim, Ben; Ord, Toby; Patel, Vikram; Patton, George C; Peabody, John; Prabhakaran, Dorairaj; Qi, Jinyuan; Reynolds, Teri; Ruacan, Sevket; Sankaranarayanan, Rengaswamy; Sepúlveda, Jaime; Skolnik, Richard; Smith, Kirk R; Temmerman, Marleen; Tollman, Stephen; Verguet, Stéphane; Walker, Damian G; Walker, Neff; Wu, Yangfeng; Zhao, Kun

2018-01-01

The World Bank is publishing nine volumes of Disease Control Priorities, 3rd edition (DCP3) between 2015 and 2018. Volume 9, Improving Health and Reducing Poverty, summarises the main messages from all the volumes and contains cross-cutting analyses. This Review draws on all nine volumes to convey conclusions. The analysis in DCP3 is built around 21 essential packages that were developed in the nine volumes. Each essential package addresses the concerns of a major professional community (eg, child health or surgery) and contains a mix of intersectoral policies and health-sector interventions. 71 intersectoral prevention policies were identified in total, 29 of which are priorities for early introduction. Interventions within the health sector were grouped onto five platforms (population based, community level, health centre, first-level hospital, and referral hospital). DCP3 defines a model concept of essential universal health coverage (EUHC) with 218 interventions that provides a starting point for country-specific analysis of priorities. Assuming steady-state implementation by 2030, EUHC in lower-middle-income countries would reduce premature deaths by an estimated 4·2 million per year. Estimated total costs prove substantial: about 9·1% of (current) gross national income (GNI) in low-income countries and 5·2% of GNI in lower-middle-income countries. Financing provision of continuing intervention against chronic conditions accounts for about half of estimated incremental costs. For lower-middle-income countries, the mortality reduction from implementing the EUHC can only reach about half the mortality reduction in non-communicable diseases called for by the Sustainable Development Goals. Full achievement will require increased investment or sustained intersectoral action, and actions by finance ministries to tax smoking and polluting emissions and to reduce or eliminate (often large) subsidies on fossil fuels appear of central importance. DCP3 is intended to

Achievements and Challenges of the 3rd Edition of Master in Nuclear Engineering and Applications MINA-2010

International Nuclear Information System (INIS)

Herranz, L. E.; Garcia Cuesta, J. C.; Falcon, S.; Marco, M.; Casas, J. A.

2011-01-01

This article provides a summary of the comparative analysis between the first three editions of the Master MINA The first part is devoted to identifying trends between generations in terms of interest, qualifications and responses to the challenges of the Master. The second provides the assessment of students in the last edition and the measures that are to be adopted accordingly. Moreover, in the last part of the presentation includes an analysis of the effects that it has had the Fukushima accident.

Guide for Conducting Benefit-Cost Evaluation of Realized Impacts of Public R&D Programs

Energy Technology Data Exchange (ETDEWEB)

Ruegg, Rosalie [TIA Consulting, Inc., Emerald Isle, NC (United States); Jordan, Gretchen B. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2011-08-01

This document provides guidance for evaluators who conduct impact assessments to determine the “realized” economic benefits and costs, energy, environmental benefits, and other impacts of the Office of Energy Efficiency and Renewable Energy’s (EERE) R&D programs. The focus of this Guide is on realized outcomes or impacts of R&D programs actually experienced by American citizens, industry, and others. Retrospective evaluations may be contrasted to prospective evaluations that reflect expected or potential outcomes only if assumptions hold. The retrospective approach described in this Guide is based on realized results only and the extent they can be attributed to the efforts of an R&D program. While it has been prepared specifically to guide retrospective benefit-cost analysis of EERE R&D Programs, this report may be used for similar analysis of other public R&D organizations.

3rd CEAS Specialist Conference on Guidance, Navigation and Control

CERN Document Server

Drouin, Antoine; Roos, Clément

2015-01-01

The two first CEAS (Council of European Aerospace Societies) Specialist Conferences on Guidance, Navigation and Control (CEAS EuroGNC) were held in Munich, Germany in 2011 and in Delft, The Netherlands in 2013. ONERA The French Aerospace Lab, ISAE (Institut Supérieur de l’Aéronautique et de l’Espace) and ENAC (Ecole Nationale de l’Aviation Civile) accepted the challenge of jointly organizing the 3rd edition. The conference aims at promoting new advances in aerospace GNC theory and technologies for enhancing safety, survivability, efficiency, performance, autonomy and intelligence of aerospace systems. It represents a unique forum for communication and information exchange between specialists in the fields of GNC systems design and operation, including air traffic management. This book contains the forty best papers and gives an interesting snapshot of the latest advances over the following topics: l  Control theory, analysis, and design l  Novel navigation, estimation, and tracking methods l  Aircr...

Specifications and Construction Methods for Asphalt Concrete and Other Plant-Mix Types, 3rd Edition.

Science.gov (United States)

Asphalt Inst., College Park, MD.

The purpose of this publication is to assist engineers in the analysis, design and control of paving projects that use asphalt concrete and other asphalt plant-mixes. The scope of this new third edition has been enlarged, and changes necessitated by advances in asphalt technology have been incorporated. Chapters I and II and Appendices A and B…

US Accelerator R&D Program Toward Intensity Frontier Machines

Energy Technology Data Exchange (ETDEWEB)

Shiltsev, Vladimir [Fermilab

2016-09-15

The 2014 P5 report indicated the accelerator-based neutrino and rare decay physics research as a centerpiece of the US domestic HEP program. Operation, upgrade and development of the accelerators for the near-term and longer-term particle physics program at the Intensity Frontier face formidable challenges. Here we discuss key elements of the accelerator physics and technology R&D program toward future multi-MW proton accelerators.

The INFN–FBK “Phase-2” R&D program

CERN Document Server

Dalla Betta, Gian-Franco; Bomben, Marco; Brianzi, Mirko; Calderini, Giovanni; Darbo, Giovanni; Dell'Orso, Roberto; Gaudiello, Andrea; Giacomini, Gabriele; Mendicino, Roberto; Meschini, Marco; Messineo, Alberto; Ronchin, Sabina; Sultan, D.M.S.; Zorzi, Nicola

2016-07-11

We report on the 3-year INFN ATLAS–CMS joint research activity in collaboration with FBK, started in 2014, and aimed at the development of new thin pixel detectors for the High Luminosity LHC Phase-2 upgrades. The program is concerned with both 3D and planar active-edge pixel sensors to be made on 6” p-type wafers. The technology and the design will be optimized and qualified for extreme radiation hardness (2×10^16 neq cm^−2). Pixel layouts compatible with present (for testing) and future (RD53 65 nm) front-end chips of ATLAS and CMS are considered. The paper covers the main aspects of the research program, from the sensor design and fabrication technology, to the results of initial tests performed on the first prototypes.

The INFN–FBK “Phase-2” R&D program

International Nuclear Information System (INIS)

Dalla Betta, G.-F.; Boscardin, M.; Bomben, M.; Brianzi, M.; Calderini, G.; Darbo, G.; Dell’Orso, R.; Gaudiello, A.; Giacomini, G.; Mendicino, R.; Meschini, M.; Messineo, A.; Ronchin, S.; Sultan, D.M.S.; Zorzi, N.

2016-01-01

We report on the 3-year INFN ATLAS–CMS joint research activity in collaboration with FBK, started in 2014, and aimed at the development of new thin pixel detectors for the High Luminosity LHC Phase-2 upgrades. The program is concerned with both 3D and planar active-edge pixel sensors to be made on 6” p-type wafers. The technology and the design will be optimized and qualified for extreme radiation hardness (2×10"1"6 n_e_q cm"−"2). Pixel layouts compatible with present (for testing) and future (RD53 65 nm) front-end chips of ATLAS and CMS are considered. The paper covers the main aspects of the research program, from the sensor design and fabrication technology, to the results of initial tests performed on the first prototypes.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Czech Academy of Sciences Publication Activity Database

Váchová, Libuše

2016-01-01

Roč. 12, č. 1 (2016), s. 1-222 ISSN 1554-8627 R&D Projects: GA MŠk(CZ) ED1.1.00/02.0109; GA MŠk(CZ) LD15129 Institutional support: RVO:61388971 Keywords : autolysosome * autophagosome * chaperone-mediated autophagy Subject RIV: EE - Microbiology, Virology Impact factor: 8.593, year: 2016

Resource Guide to Careers in Toxicology, 3rd Edition.

Science.gov (United States)

Society of Toxicology, Reston, VA.

This resource guide was prepared by the Tox 90's Educational Issues Task Force of the Society of Toxicology. The introduction provides information on the Society of Toxicology and financial support for graduate students in toxicology. Other sections include career opportunities in toxicology, academic and postdoctoral programs in toxicology, and…

PREFACE: 3rd International Conference of Mechanical Engineering Research (ICMER 2015)

Science.gov (United States)

Mamat, Riazalman; Rahman, Mustafizur; Mohd. Zuki Nik Mohamed, Nik; Che Ghani, Saiful Anwar; Harun, Wan Sharuzi Wan

2015-12-01

The 3rd ICMER2015 is the continuity of the NCMER2010. The year 2010 represents a significant milestone in the history for Faculty of Mechanical Engineering, Universiti Malaysia Pahang (UMP) Malaysia with the organization of the first and second national level conferences (1st and 2nd NCMER) at UMP on May 26-27 and Dec 3-4 2010. The Faculty then changed the name from National Conference on Mechanical Engineering Research (NCMER) to International Conference on Mechanical Engineering Research (ICMER) in 2011 and this year, 2015 is our 3rd ICMER. These proceedings contain the selected scientific manuscripts submitted to the conference. It is with great pleasure to welcome you to the "International Conference on Mechanical Engineering Research (ICMER2015)" that is held at Zenith Hotel, Kuantan, Malaysia. The call for papers attracted submissions of over two hundred abstracts from twelve different countries including Japan, Iran, China, Kuwait, Indonesia, Norway, Philippines, Morocco, Germany, UAE and more. The scientific papers published in these proceedings have been revised and approved by the technical committee of the 3rd ICMER2015. All of the papers exhibit clear, concise, and precise expositions that appeal to a broad international readership interested in mechanical engineering, combustion, metallurgy, materials science as well as in manufacturing and biomechanics. The reports present original ideas or results of general significance supported by clear reasoning and compelling evidence, and employ methods, theories and practices relevant to the research. The authors clearly state the questions and the significance of their research to theory and practice, describe how the research contributes to new knowledge, and provide tables and figures that meaningfully add to the narrative. In this edition of ICMER representatives attending are from academia, industry, governmental and private sectors. The plenary and invited speakers will present, discuss, promote and

Overview of Evaluation Methods for R&D Programs. A Directory of Evaluation Methods Relevant to Technology Development Programs

Energy Technology Data Exchange (ETDEWEB)

Ruegg, Rosalie [TIA Consulting, Inc., Emeral Isle, NC (United States); Jordan, Gretchen B. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2007-03-01

This document provides guidance for evaluators who conduct impact assessments to determine the “realized” economic benefits and costs, energy, environmental benefits, and other impacts of the Office of Energy Efficiency and Renewable Energy’s (EERE) R&D programs. The focus of this Guide is on realized outcomes or impacts of R&D programs actually experienced by American citizens, industry, and others.

Economic Education Programs and Resources Directory. Second Edition.

Science.gov (United States)

National Association of Manufacturers, Washington, DC.

This directory provides a selective listing of information about economic education programs and resource activities of 299 corporations, organizations, universities, and colleges in the United States. This second edition of the directory is intended to stimulate interaction between business firms and schools and to help educators, members of the…

The INFN–FBK “Phase-2” R&D program

Energy Technology Data Exchange (ETDEWEB)

Dalla Betta, G.-F., E-mail: gianfranco.dallabetta@unitn.it [Università di Trento, Dipartimento di Ingegneria Industriale, I-38123 Trento (Italy); TIFPA INFN, I-38123 Trento (Italy); Boscardin, M. [Fondazione Bruno Kessler (FBK), I-38123 Trento (Italy); TIFPA INFN, I-38123 Trento (Italy); Bomben, M. [Laboratoire de Physique Nucleaire et de Hautes Énergies (LPNHE), 75252 Paris (France); Brianzi, M. [INFN Sezione di Firenze, I-50019 Sesto Fiorentino (Italy); Calderini, G. [Laboratoire de Physique Nucleaire et de Hautes Énergies (LPNHE), 75252 Paris (France); Università di Pisa, Dipartimento di Fisica, I-56127 Pisa (Italy); INFN Sezione di Pisa, I-56127 Pisa (Italy); Darbo, G. [INFN Sezione di Genova, I-16146 Genova (Italy); Dell’Orso, R. [INFN Sezione di Pisa, I-56127 Pisa (Italy); Gaudiello, A. [Università di Genova, Dipartimento di Fisica, I-16146 Genova (Italy); INFN Sezione di Genova, I-16146 Genova (Italy); Giacomini, G. [Fondazione Bruno Kessler (FBK), I-38123 Trento (Italy); Mendicino, R. [Università di Trento, Dipartimento di Ingegneria Industriale, I-38123 Trento (Italy); TIFPA INFN, I-38123 Trento (Italy); Meschini, M. [INFN Sezione di Firenze, I-50019 Sesto Fiorentino (Italy); Messineo, A. [Università di Pisa, Dipartimento di Fisica, I-56127 Pisa (Italy); INFN Sezione di Pisa, I-56127 Pisa (Italy); Ronchin, S. [Fondazione Bruno Kessler (FBK), I-38123 Trento (Italy); Sultan, D.M.S. [Università di Trento, Dipartimento di Ingegneria Industriale, I-38123 Trento (Italy); TIFPA INFN, I-38123 Trento (Italy); Zorzi, N. [Fondazione Bruno Kessler (FBK), I-38123 Trento (Italy); TIFPA INFN, I-38123 Trento (Italy)

2016-07-11

We report on the 3-year INFN ATLAS–CMS joint research activity in collaboration with FBK, started in 2014, and aimed at the development of new thin pixel detectors for the High Luminosity LHC Phase-2 upgrades. The program is concerned with both 3D and planar active-edge pixel sensors to be made on 6” p-type wafers. The technology and the design will be optimized and qualified for extreme radiation hardness (2×10{sup 16} n{sub eq} cm{sup −2}). Pixel layouts compatible with present (for testing) and future (RD53 65 nm) front-end chips of ATLAS and CMS are considered. The paper covers the main aspects of the research program, from the sensor design and fabrication technology, to the results of initial tests performed on the first prototypes.

Sandstone columns of the 3rd Nile Cataract (Nubia, Northern Sudan)

Czech Academy of Sciences Publication Activity Database

Cílek, Václav; Adamovič, Jiří; Suková, L.

2015-01-01

Roč. 59, Supplement 1 (2015), s. 151-165 ISSN 0372-8854 Grant - others:Program interní podpory projektů mezinárodní spolupráce AV ČR(CZ) M100130902 Institutional support: RVO:67985831 Keywords : Nubian sandstone * columnar jointing * Voronoi fragmentation * 3rd Nile Cataract * Sudan Subject RIV: DB - Geology ; Mineralogy Impact factor: 1.103, year: 2015

Developing Product Lines with 3rd-party components

NARCIS (Netherlands)

De Jonge, M.

2007-01-01

The trends toward product line development and toward adopting more 3rd-party software are hard to combine. The reason is that productlines demand fine control over the software (e.g., for diversity management), while 3rd-party software (almost by definition) provides only little or no control. A

Lecture Notes in Statistics. 3rd Semester

DEFF Research Database (Denmark)

The lecture note is prepared to meet the requirements for the 3rd semester course in statistics at the Aarhus School of Business. It focuses on multiple regression models, analysis of variance, and log-linear models.......The lecture note is prepared to meet the requirements for the 3rd semester course in statistics at the Aarhus School of Business. It focuses on multiple regression models, analysis of variance, and log-linear models....

AN ANALYSIS OF STUDENTS’ SPEAKING ABILITY IN ENGLISH CONVERSATION CLUB (ECC PROGRAM AT THE 3rd SEMESTER

Directory of Open Access Journals (Sweden)

M. Fadhly Farhy Abbas

2017-07-01

Full Text Available This research is based on students’ speaking ability who had followed the EnglishConversation Club (ECC program especially for the third semester of English Department. Thepurpose of this study was to analyze the students’ speaking ability at the 3rd semester in the EnglishConversation Club FKIP UNILAK Pekanbaru. The type of the research was mixed method in typeof explanatory design. The number of participant was 53 students. The researcher used twoinstruments, those were test and interview. In analyzing the data, it used in descriptive statistics.The result of the analysis showed that the average score of 3rd semester students’ speaking abilitywas 45.42. It can be concluded that the students’ speaking ability was categorized into failed . Thescore of Standard Deviation was 7.02, Variance was 49.30, and Range was 36 points . It meansthat the students’ speaking ability was homogeneous. According to the Z-Score, it can be seen that49.06% students’ ability was higher than average and 50.94% students ability was below theaverage. In conclusion, the students’ ability in learning speaking English was failed, it had beenaffected by some factors, those were lack of vocabulary, grammar and motivation. It was supportedby the interview, eventhough the students’ perception to English Conversation Club (ECCprogram was positive, but in fact, the students’ frequency to speak English was seldom, they wereless practice speaking English everyday.Keywords : Speaking , English Conversation Club (ECC

Star Ware: The Amateur Astronomer's Guide to Choosing, Buying, and Using Telescopes and Accessories, 3rd Edition

Science.gov (United States)

Harrington, Philip S.

2002-05-01

Praise for the Second Edition of Star Ware "Star Ware is still a tour de force that any experienced amateur will find invaluable, and which hardware-minded beginners will thoroughly enjoy." -Robert Burnham, Sky & Telescope magazine "Star Ware condenses between two covers what would normally take a telescope buyer many months to accumulate." -John Shibley, Astronomy magazine Now more than ever, the backyard astronomer has a dazzling array of choices when it comes to telescope shopping-which can make choosing just the right sky-watching equipment a formidable challenge. In this revised and updated edition of Star Ware, the essential guide to buying astronomical equipment, award-winning astronomy writer Philip Harrington does the work for you, analyzing and exploring today's astronomy market and offering point-by-point comparisons of everything you need. Whether you're an experienced amateur astronomer or just getting started, Star Ware, Third Edition will prepare you to explore the farthest reaches of space with: Extensive, expanded reviews of leading models and accessories, including dozens of new products, to help you buy smart A clear, step-by-step guide to all aspects of purchasing everything from telescopes and binoculars to filters, mounts, lenses, cameras, film, star charts, guides and references, and much more Eleven new do-it-yourself projects for making unique astronomical equipment at home Easy tips on maintenance, photography, and star-mapping to help you get the most out of your telescope Lists of where to find everything astronomical, including Internet sites and Web resources; distributors, dealers, and conventions; and corporate listings for products and services

Financing R&D Projects in Southern Italy: The “Technological Vouchers and Cooperative Research” Program

Directory of Open Access Journals (Sweden)

Gianpaolo Iazzolino

2013-09-01

Full Text Available The paper deals with the evaluation and financing of research and innovation projects. The paper analyzes and discusses the “Technological Vouchers and Cooperative Research” program in the Calabria Region (Southern Italy, as a program for financing R&D projects in a geographical area far behind in development. Three real cases of R&D projects are described. The program was effective as regards the stimulus to realizing R&D activities by Calabrian SMEs and furthermore in relation to the improvement of cooperation between SMEs, research centers, universities and technological laboratories. The weak points of the program mainly regard the evaluation phase that made it impossible to get a feedback useful for policy and for driving future agenda.

The R+D radiological protection program in the European Communities

International Nuclear Information System (INIS)

Mingot Buades, F.

1993-01-01

The R+D program a radiological protection for the year 1992 has lied basically on three areas: I .- Radiological exposure of man II .- Radiation effects on man (evaluation, prevention and treatment) III.- Risks and management of radiation exposure

R&D of Nb$_{3}$Sn accelerator magnets at Fermilab

CERN Document Server

Zlobin, A V; Andreev, N; Barzi, E; Bordini, B; Bossert, R; Carcagno, R; Chichili, D R; Di Marco, J; Elementi, L; Fehér, S; Kashikhin, V S; Kashikhin, V V; Kephart, R; Lamm, M J; Limon, P J; Novitski, I; Orris, D; Pischalnikov, Y; Schlabach, P; Stanek, R; Strait, J; Sylvester, C D; Tartaglia, M; Tompkins, J C; Turrioni, D; Velev, G; Yamada, R; Yarba, V A; 10.1109/TASC.2005.849507

2005-01-01

Fermilab is developing and investigating different high-field magnets (HFM) for present and future accelerators. The HFM R&D program focused on the 10-12 T magnets based on Nb/sub 3/Sn superconductor and explored both basic magnet technologies for brittle superconductors-wind-and-react and react-and-wind. Magnet design studies in support of LHC upgrades and VLHC were conducted. A series of 1-m long cos-theta dipole models based on the wind-and-react technique was fabricated and tested. Three 1-m long flat racetracks and the common coil dipole model, based on a single-layer coil and react-and-wind technique, were also fabricated and tested. Extensive theoretical and experimental studies of electro-magnetic instabilities in Nb/sub 3/Sn strands, cables and magnets were performed and led to a successful 10 T dipole model. This paper presents the details of Fermilab's HFM program, reports its status and major results, and formulates the next steps for the program.

Labview advanced programming techniques, second edition

CERN Document Server

Bitter, Rick; Nawrocki, Matt

2006-01-01

Whether seeking deeper knowledge of LabVIEW®'s capabilities or striving to build enhanced VIs, professionals know they will find everything they need in LabVIEW: Advanced Programming Techniques. Now accompanied by LabVIEW 2011, this classic second edition, focusing on LabVIEW 8.0, delves deeply into the classic features that continue to make LabVIEW one of the most popular and widely used graphical programming environments across the engineering community. The authors review the front panel controls, the Standard State Machine template, drivers, the instrument I/O assistant, error handling functions, hyperthreading, and Express VIs. It covers the introduction of the Shared Variables function in LabVIEW 8.0 and explores the LabVIEW project view. The chapter on ActiveX includes discussion of the Microsoft™ .NET® framework and new examples of programming in LabVIEW using .NET. Numerous illustrations and step-by-step explanations provide hands-on guidance. Reviewing LabVIEW 8.0 and accompanied by the latest s...

Machining Data Handbook. 3rd Edition. Volume 2

Science.gov (United States)

1980-01-01

HY230 50 ORC age 250 Grade 7 ASTM A538: Grades A, B. C I 8. TOOL STEELS , WROUGHT r~n 5 05.05 1-. Group I 00 t oBOT5 A2 H13 L6 P20 8000 125 Finish: (Max...max 50 R ~ Maraged 0 Rough 112 8. TOOL STEELS , WROUGH4T Rough0 60/2 Group I to40 to 0 P2 H13 L6 P20 6500 !00 Finish- A3 H14 L7 P21 50 R Annealed 0005max...Over .0002 max. 50 Rc Maraged - s- . .__.. _ GroupRough: 8. TOOL STEELS , WROUGHT 1 5000 75 o.00 1/3 to to A60MV A2 H13 L6 P20 6500 200 Finish: A3 H14

Evaluating Realized Impacts of DOE/EERE R&D Programs. Standard impact evaluation method

Energy Technology Data Exchange (ETDEWEB)

Ruegg, Rosalie [TIA Consulting, Inc. (United States); O' Connor, Alan C. [RTI International, Research Triangle Park, NC (United States); Loomis, Ross J. [RTI International, Research Triangle Park, NC (United States)

2014-08-01

This document provides guidance for evaluators who conduct impact assessments of research and development (R&D) programs for the U.S. Department of Energy’s (DOE) Office of Energy Efficiency and Renewable Energy (EERE). It is also targeted at EERE program staff responsible for initiating and managing commissioned impact studies. The guide specifies how to estimate economic benefits and costs, energy saved and installed or generated, environmental impacts, energy security impacts, and knowledge impacts of R&D investments in advanced energy technologies.

Reading Improvement through Art Replicator Manual of Instruction, 3rd Edition

Science.gov (United States)

Corwin, Sylvia K., Ed.

2013-01-01

Reading Improvement Through Art (RITA) program is an interdisciplinary approach to literacy that blends visual art with reading comprehension, evaluated in nine New York City urban high schools. 240 problem readers participating in the pilot program were pre- and post-tested in the Fall 1975 and Spring 1976 semesters. The testing showed the 9th…

R&D Proposal for the National Muon Acccelerator Program

Energy Technology Data Exchange (ETDEWEB)

2010-02-01

This document contains a description of a multi-year national R&D program aimed at completing a Design Feasibility Study (DFS) for a Muon Collider and, with international participation, a Reference Design Report (RDR) for a muon-based Neutrino Factory. It also includes the supporting component development and experimental efforts that will inform the design studies and permit an initial down-selection of candidate technologies for the ionization cooling and acceleration systems. We intend to carry out this plan with participants from the host national laboratory (Fermilab), those from collaborating U.S. national laboratories (ANL, BNL, Jlab, LBNL, and SNAL), and those from a number of other U.S. laboratories, universities, and SBIR companies. The R&D program that we propose will provide the HEP community with detailed information on future facilities based on intense beams of muons - the Muon Collider and the Neutrino Factory. We believe that these facilities offer the promise of extraordinary physics capabilities. The Muon Collider presents a powerful option to explore the energy frontier and the Neutrino Factory gives the opportunity to perform the most sensitive neutrino oscillation experiments possible, while also opening expanded avenues for the study of new physics in the neutrino sector. The synergy between the two facilities presents the opportunity for an extremely broad physics program and a unique pathway in accelerator facilities. Our work will give clear answers to the questions of expected capabilities and performance of these muon-based facilities, and will provide defensible ranges for their cost. This information, together with the physics insights gained from the next-generation neutrino and LHC experiments, will allow the HEP community to make well-informed decisions regarding the optimal choice of new facilities. We believe that this work is a critical part of any broad strategic program in accelerator R&D and, as the P5 panel has recently

R&D PROPOSAL FOR THE NATIONAL MUON ACCELERATOR PROGRAM

Energy Technology Data Exchange (ETDEWEB)

Muon Accelerator Program; Zisman, Michael S.; Geer, Stephen

2010-02-24

This document contains a description of a multi-year national R&D program aimed at completing a Design Feasibility Study (DFS) for a Muon Collider and, with international participation, a Reference Design Report (RDR) for a muon-based Neutrino Factory. It also includes the supporting component development and experimental efforts that will inform the design studies and permit an initial down-selection of candidate technologies for the ionization cooling and acceleration systems. We intend to carry out this plan with participants from the host national laboratory (Fermilab), those from collaborating U.S. national laboratories (ANL, BNL, Jlab, LBNL, and SNAL), and those from a number of other U.S. laboratories, universities, and SBIR companies. The R&D program that we propose will provide the HEP community with detailed information on future facilities based on intense beams of muons--the Muon Collider and the Neutrino Factory. We believe that these facilities offer the promise of extraordinary physics capabilities. The Muon Collider presents a powerful option to explore the energy frontier and the Neutrino Factory gives the opportunity to perform the most sensitive neutrino oscillation experiments possible, while also opening expanded avenues for the study of new physics in the neutrino sector. The synergy between the two facilities presents the opportunity for an extremely broad physics program and a unique pathway in accelerator facilities. Our work will give clear answers to the questions of expected capabilities and performance of these muon-based facilities, and will provide defensible ranges for their cost. This information, together with the physics insights gained from the next-generation neutrino and LHC experiments, will allow the HEP community to make well-informed decisions regarding the optimal choice of new facilities. We believe that this work is a critical part of any broad strategic program in accelerator R&D and, as the P5 panel has recently

MP3 audio-editing software for the department of radiology

International Nuclear Information System (INIS)

Hong Qingfen; Sun Canhui; Li Ziping; Meng Quanfei; Jiang Li

2006-01-01

Objective: To evaluate the MP3 audio-editing software in the daily work in the department of radiology. Methods: The audio content of daily consultation seminar, held in the department of radiology every morning, was recorded and converted into MP3 audio format by a computer integrated recording device. The audio data were edited, archived, and eventually saved in the computer memory storage media, which was experimentally replayed and applied in the research or teaching. Results: MP3 audio-editing was a simple process and convenient for saving and searching the data. The record could be easily replayed. Conclusion: MP3 audio-editing perfectly records and saves the contents of consultation seminar, and has replaced the conventional hand writing notes. It is a valuable tool in both research and teaching in the department. (authors)

PREFACE: 3rd International Congress on Ceramics (ICC3)

Science.gov (United States)

Niihara, Koichi; Ohji, Tatsuki; Sakka, Yoshio

2011-10-01

Early in 2005, the American Ceramic Society, the European Ceramic Society and the Ceramic Society of Japan announced a collaborative effort to provide leadership for the global ceramics community that would facilitate the use of ceramic and glass materials. That effort resulted in an agreement to organize a new biennial series of the International Congress on Ceramics, convened by the International Ceramic Federation (ICF). In order to share ideas and visions of the future for ceramic and glass materials, the 1st International Congress on Ceramics (ICC1) was held in Canada, 2006, under the organization of the American Ceramic Society, and the 2nd Congress (ICC2) was held in Italy, 2008, hosted by the European Ceramic Society. Organized by the Ceramic Society of Japan, the 3rd Congress (ICC3) was held in Osaka, Japan, 14-18 November 2010. Incorporating the 23rd Fall Meeting of the Ceramic Society of Japan and the 20th Iketani Conference, ICC3 was also co-organized by the Iketani Science and Technology Foundation, and was endorsed and supported by ICF, Asia-Oceania Ceramic Federation (AOCF) as well as many other organizations. Following the style of the previous two successful Congresses, the program was designed to advance ceramic and glass technologies to the next generation through discussion of the most recent advances and future perspectives, and to engage the worldwide ceramics community in a collective effort to expand the use of these materials in both conventional as well as new and exciting applications. ICC3 consisted of 22 voluntarily organized symposia in the most topical and essential themes of ceramic and glass materials, including Characterization, design and processing technologies Electro, magnetic and optical ceramics and devices Energy and environment related ceramics and systems Bio-ceramics and bio-technologies Ceramics for advanced industry and safety society Innovation in traditional ceramics It also contained the Plenary Session and the

3rd IDPASC School

CERN Document Server

Lectures on particle physics, astrophysics and cosmology

2015-01-01

This volume gathers the content of the courses held at the Third IDPASC School, which took place in San Martiño Pinario, Hospederia and Seminario Maior, in the city of Santiago de Compostela, Galiza, Spain, from January 21st to February 2nd, 2013. This school is the annual joint program of the International Doctorate Network in Particle Physics, Astrophysics, and Cosmology (IDPASC).   The purpose of the school series is to present doctoral students from different universities and laboratories in Europe and beyond with a broad range of the latest results and current state of the art in the fields of Particle Physics, Astrophysics, and Cosmology, and to further introduce them to both the questions now posed by the potentials of physics and to challenges connected with current and future experiments – in particular, with the newly available energy ranges.   Following these guidelines, the content of this third edition of the IDPASC School was jointly planned by the Academic Council and by the network’s In...

RD50 Prolongation Request 2018

CERN Document Server

Casse, Gianluigi

2018-01-01

With this document, we request the prolongation of the CERN RD50 research program for 5 years. A very brief historical review of the RD50 research program since the RD50 project approval by the Research Board in the year 2002 is presented and the biggest RD50 achievements are highlighted. The present composition of the collaboration, its organizational structure, and the research methodology are described. The role of RD50 in the present various upgrade and research programs of the LHC Experiments community is given and the overall work plan explained. Finally, a detailed 5-years work program with precise milestones and deliverables for the various research activities is presented. We conclude with our prolongation request towards the LHCC.

Summary of the 3rd workshop on the reduced-moderation water reactor

International Nuclear Information System (INIS)

Ishikawa, Nobuyuki; Nakatsuka, Tohru; Iwamura, Takamichi

2000-06-01

The research activities of a Reduced-Moderation Water Reactor (RMWR) are being performed for a development of the next generation water-cooled reactor. A workshop on the RMWR was held on March 3rd 2000 aiming to exchange information between JAERI and other organizations such as universities, laboratories, utilities and vendors. This report summarizes the contents of lectures and discussions on the workshop. The 1st workshop was held on March 1998 focusing on the review of the research activities and future research plan. The succeeding 2nd workshop was held on March 1999 focusing on the topics of the plutonium utilization in water-cooled reactors. The 3rd workshop was held on March 3rd 2000, which was attended by 77 participants. The workshop began with a lecture titled 'Recent Situation Related to Reduced-Moderation Water Reactor (RMWR)', followed by 'Program on MOX Fuel Utilization in Light Water Reactors' which is the mainstream scenario of plutonium utilization by utilities, and 'Feasibility Studies on Commercialized Fast Breeder Reactor Cycle System' mainly conducted by Japan Nuclear Cycle Development Institute (JNC). Also, following lectures were given as the recent research activities in JAERI: 'Progress in Design Study on Reduced-Moderation Water Reactors', 'Long-Term Scenarios of Power Reactors and Fuel Cycle Development and the Role of Reduced Moderation Water Reactors', 'Experimental and Analytical Study on Thermal Hydraulics' and Reactor Physics Experiment Plan using TCA'. At the end of the workshop, a general discussion was performed about the research and development of the RMWR. This report includes the original papers presented at the workshop and summaries of the questions and answers for each lecture and general discussion, as well as presentation viewgraphs, program and participant list as appendixes. The 7 of the presented papers are indexed individually. (J.P.N.)

Summary of the 3rd workshop on the reduced-moderation water reactor

Energy Technology Data Exchange (ETDEWEB)

Ishikawa, Nobuyuki; Nakatsuka, Tohru; Iwamura, Takamichi [eds.

2000-06-01

The research activities of a Reduced-Moderation Water Reactor (RMWR) are being performed for a development of the next generation water-cooled reactor. A workshop on the RMWR was held on March 3rd 2000 aiming to exchange information between JAERI and other organizations such as universities, laboratories, utilities and vendors. This report summarizes the contents of lectures and discussions on the workshop. The 1st workshop was held on March 1998 focusing on the review of the research activities and future research plan. The succeeding 2nd workshop was held on March 1999 focusing on the topics of the plutonium utilization in water-cooled reactors. The 3rd workshop was held on March 3rd 2000, which was attended by 77 participants. The workshop began with a lecture titled 'Recent Situation Related to Reduced-Moderation Water Reactor (RMWR)', followed by 'Program on MOX Fuel Utilization in Light Water Reactors' which is the mainstream scenario of plutonium utilization by utilities, and 'Feasibility Studies on Commercialized Fast Breeder Reactor Cycle System' mainly conducted by Japan Nuclear Cycle Development Institute (JNC). Also, following lectures were given as the recent research activities in JAERI: 'Progress in Design Study on Reduced-Moderation Water Reactors', 'Long-Term Scenarios of Power Reactors and Fuel Cycle Development and the Role of Reduced Moderation Water Reactors', 'Experimental and Analytical Study on Thermal Hydraulics' and Reactor Physics Experiment Plan using TCA'. At the end of the workshop, a general discussion was performed about the research and development of the RMWR. This report includes the original papers presented at the workshop and summaries of the questions and answers for each lecture and general discussion, as well as presentation viewgraphs, program and participant list as appendixes. The 7 of the presented papers are indexed individually. (J.P.N.)

Fundamentals of Welding. Teacher Edition [and] Student Edition [and] Student Workbook. Second Edition.

Science.gov (United States)

Fortney, Clarence; Gregory, Mike; New, Larry

Teacher and student editions and a student workbook for fundamentals of welding comprise the first of six in a series of competency-based instructional materials for welding programs. Introductory pages in the teacher edition are training and competency profile, instructional/task analysis, basic skills icons and classifications, basic skills…

Vom work Book Journal, 2011 3rd Edition

African Journals Online (AJOL)

USER

relieve constipation in man and animals. Senna cinnamonum is the source of aromatic stomachic, ... feeding the plant to the animals. KEYWORDS: Senna obtusifolia, feedstuff, digestibility, ... Vol. 32(3): 2011; 199 - 203. ARTICLE. Utilization of Senna obtusifolia as a Potential Non-Conventional Feedstuff. In Sheep. 1. 2. 2. 1.

Short-term diagnostic stability of probable headache disorders based on the International Classification of Headache Disorders, 3rd edition beta version, in first-visit patients: a multicenter follow-up study.

Science.gov (United States)

Kim, Byung-Su; Moon, Heui-Soo; Sohn, Jong-Hee; Cha, Myong-Jin; Song, Tae-Jin; Kim, Jae-Moon; Park, Jeong Wook; Park, Kwang-Yeol; Cho, Soo-Jin; Kim, Soo-Kyoung

2016-01-01

A "Probable headache disorder" is diagnosed when a patient's headache fulfills all but one criterion of a headache disorder in the 3rd beta edition of the International Classification of Headache Disorder (ICHD-3β). We investigated diagnostic changes in probable headache disorders in first-visit patients after at least 3 months of follow-up. This was a longitudinal study using a prospective headache registry from nine headache clinics of referral hospitals. The diagnostic change of probable headache disorders at baseline was assessed at least 3 months after the initial visit using ICHD-3β. Of 216 patients with probable headache disorders at baseline, the initial probable diagnosis remained unchanged for 162 (75.0 %) patients, while it progressed to a definite diagnosis within the same headache subtype for 45 (20.8 %) by fulfilling the criteria during a median follow-up period of 6.5 months. Significant difference on the proportions of constant diagnosis was not found between headache subtypes (P headache (TTH), and 76.0 % for probable other primary headache disorders (OPHD). Among patients with headache recurrence, the proportion of constant diagnosis was higher for probable migraine than for probable TTH plus probable OPHD (59.2 vs. 23.1 %; P 3 and ≤ 6 months vs. > 6 and ≤ 10 months) in probable migraine, probable TTH, and probable OPHD, respectively. In this study, a probable headache diagnosis, based on ICHD-3β, remained in approximately three-quarters of the outpatients; however, diagnostic stability could differ by headache recurrence and subtype. Probable headache management might have to consider these differences.

Impressions from the 3rd Nordcode Seminar & Workshop

DEFF Research Database (Denmark)

Lenau, Torben Anker; Boelskifte, Per; Hansen, Claus Thorp

2005-01-01

This paper summarises the purpose and contents of the 3rd Nordcode Seminar and Workshop. First, the workshop assignments are described. Second, the paper briefly presents the topics of the keynote speeches and all presentations of the working papers that took place in the seminar.......This paper summarises the purpose and contents of the 3rd Nordcode Seminar and Workshop. First, the workshop assignments are described. Second, the paper briefly presents the topics of the keynote speeches and all presentations of the working papers that took place in the seminar....

The World Health Organization Classification of dontogenic Lesions: A Summary of the Changes of the 2017 (4th Edition

Directory of Open Access Journals (Sweden)

Merva SOLUK-TEKKEŞİN

2018-01-01

Full Text Available The 4th edition of the World Health Organization (WHO Classification of Head and Neck Tumors was published in January 2017. The edition serves to provide an updated classification scheme, and extended genetic and molecular data that are useful as diagnostic tools for the lesions of the head and neck region. This review focuses on the most current update of odontogenic cysts and tumors based on the 2017 WHO edition. The updated classification has some important differences from the 3rd edition (2005, including a new classification of odontogenic cysts, ‘reclassified’ odontogenic tumors, and some new entities.

File list: Oth.Lar.50.AllAg.3rd_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: Oth.Lar.10.AllAg.3rd_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: Oth.Lar.20.AllAg.3rd_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: Oth.Lar.05.AllAg.3rd_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available Oth.Lar.05.AllAg.3rd_instar dm3 TFs and others Larvae 3rd instar SRX104964,SRX10496...1403,SRX495243 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Lar.05.AllAg.3rd_instar.bed ...

3rd International Conference on Computer Science, Applied Mathematics and Applications

CERN Document Server

Nguyen, Ngoc; Do, Tien

2015-01-01

This volume contains the extended versions of papers presented at the 3rd International Conference on Computer Science, Applied Mathematics and Applications (ICCSAMA 2015) held on 11-13 May, 2015 in Metz, France. The book contains 5 parts: 1. Mathematical programming and optimization: theory, methods and software, Operational research and decision making, Machine learning, data security, and bioinformatics, Knowledge information system, Software engineering. All chapters in the book discuss theoretical and algorithmic as well as practical issues connected with computation methods & optimization methods for knowledge engineering and machine learning techniques.  

File list: Pol.Lar.10.AllAg.3rd_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available Pol.Lar.10.AllAg.3rd_instar dm3 RNA polymerase Larvae 3rd instar SRX287908,SRX28790...7,SRX013070,SRX013082 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Pol.Lar.10.AllAg.3rd_instar.bed ...

File list: Pol.Lar.50.AllAg.3rd_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: ALL.Lar.50.AllAg.3rd_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: Pol.Lar.05.AllAg.3rd_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: Pol.Lar.20.AllAg.3rd_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available Pol.Lar.20.AllAg.3rd_instar dm3 RNA polymerase Larvae 3rd instar SRX287908,SRX28790...7,SRX013070,SRX013082 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Pol.Lar.20.AllAg.3rd_instar.bed ...

High field accelerator magnet R&D in Europe

CERN Document Server

Devred, Arnaud; Bottura, L; Chorowski, M; Fabbricatore, P; Leroy, D; den Ouden, A; Rifflet, J M; Rossi, L; Vincent-Viry, O; Volpini, G

2004-01-01

The LHC magnet R&D program has shown that the limit of NbTi technology at 1.9 K was in the 10-to-10.5-T range. Hence, to go beyond the 10-T threshold, it is necessary to change the superconducting material. Given the state of the art in HTS, the only serious candidate is Nb$_{3}$Sn. A series of dipole magnet models built at Twente University and LBNL as well as a vigorous program carried out at Fermilab have demonstrated the feasibility of Nb$_{3}$Sn magnet technology. The next step is to bring this technology to maturity, which require further conductor and conductor insulation development and a simplification of manufacturing processes. After a brief history, we review ongoing R&D programs in Europe and we present the Next European Dipole (NED) initiative promoted by the European Steering Group on Accelerator R&D (ESGARD).

R&D PROPOSAL FOR THE NATIONAL MUON ACCELERATOR PROGRAM

OpenAIRE

Zisman, Michael S.

2011-01-01

This document contains a description of a multi-year national R&D program aimed at completing a Design Feasibility Study (DFS) for a Muon Collider and, with international participation, a Reference Design Report (RDR) for a muon-based Neutrino Factory. It also includes the supporting component development and experimental efforts that will inform the design studies and permit an initial down-selection of candidate technologies for the ionization cooling and acceleration systems. We intend to ...

A trace display and editing program for data from fluorescence based sequencing machines.

Science.gov (United States)

Gleeson, T; Hillier, L

1991-12-11

'Ted' (Trace editor) is a graphical editor for sequence and trace data from automated fluorescence sequencing machines. It provides facilities for viewing sequence and trace data (in top or bottom strand orientation), for editing the base sequence, for automated or manual trimming of the head (vector) and tail (uncertain data) from the sequence, for vertical and horizontal trace scaling, for keeping a history of sequence editing, and for output of the edited sequence. Ted has been used extensively in the C.elegans genome sequencing project, both as a stand-alone program and integrated into the Staden sequence assembly package, and has greatly aided in the efficiency and accuracy of sequence editing. It runs in the X windows environment on Sun workstations and is available from the authors. Ted currently supports sequence and trace data from the ABI 373A and Pharmacia A.L.F. sequencers.

File list: ALL.Lar.05.AllAg.3rd_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available ALL.Lar.05.AllAg.3rd_instar dm3 All antigens Larvae 3rd instar SRX104964,SRX104963,...SRX287718,SRX331401,SRX287658,SRX331366,SRX287906,SRX287678 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.05.AllAg.3rd_instar.bed ...

File list: ALL.Lar.10.AllAg.3rd_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: ALL.Lar.20.AllAg.3rd_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: Unc.Lar.50.AllAg.3rd_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available Unc.Lar.50.AllAg.3rd_instar dm3 Unclassified Larvae 3rd instar SRX1038029,SRX103803...1,SRX1038032,SRX1038030,SRX022335,SRX032124,SRX032123,SRX013058 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Lar.50.AllAg.3rd_instar.bed ...

FERMILAB ACCELERATOR R&D PROGRAM TOWARDS INTENSITY FRONTIER ACCELERATORS : STATUS AND PROGRESS

Energy Technology Data Exchange (ETDEWEB)

Shiltsev, Vladimir [Fermilab

2016-11-15

The 2014 P5 report indicated the accelerator-based neutrino and rare decay physics research as a centrepiece of the US domestic HEP program at Fermilab. Operation, upgrade and development of the accelerators for the near- term and longer-term particle physics program at the Intensity Frontier face formidable challenges. Here we discuss key elements of the accelerator physics and technology R&D program toward future multi-MW proton accelerators and present its status and progress. INTENSITY FRONTIER ACCELERATORS

File list: Unc.Lar.10.AllAg.3rd_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: Unc.Lar.20.AllAg.3rd_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: Unc.Lar.05.AllAg.3rd_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available Unc.Lar.05.AllAg.3rd_instar dm3 Unclassified Larvae 3rd instar SRX1038031,SRX103802...9,SRX1038032,SRX1038030,SRX022335,SRX022334,SRX032124,SRX013058,SRX032123 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Lar.05.AllAg.3rd_instar.bed ...

Summary of findings of the R&D committee

Energy Technology Data Exchange (ETDEWEB)

Kenley, C.R. [Lockheed Martin Idaho Technologies, Idaho Falls (United States); Kokenge, B.R. [BRK Associates Inc., Farmersville, OH (United States)

1996-05-01

In March 1995, the Department of Energy`s (DOE) Nuclear Materials Stabilization Task Group (NMST) chartered a committee to formulate a research and development (R&D) plan in response to Sub-recommendation (2) of Defense Nuclear Facilities Safety Board (DNFSB) Recommendation 94-1. The NMSTG was established as an organizational unit operating under the auspices of the DOE Office of the Environmental Management. As a result of its efforts, the Research Committee concluded that, in general, the technology needs for stabilizing 94-1 nuclear materials are being adequately met by existing or planned DOE programs. At the same time, the committee, in the form of recommendations, noted specific R&D program areas that should be addressed by the NMSTG. These recommendations are documented in the R&D plan and formulated based on: (1) existing {open_quotes}gaps{close_quotes} in DOE`s R&D stabilization program, (2) the relative maturity of various technologies, and (3) other important R&D program issues that, in the judgement of the committee, should be addressed by the NMSTG. A systems engineering approach, derived form the aerospace industry, was applied to the various stabilization technologies to assess their relative maturity and availability for use in treating 94-1 nuclear materials.

Alaska Highway bibliography, 3rd edition

DEFF Research Database (Denmark)

Prange, Laurie

Since the early 20th century various schemes were considered for the construction of roads, trails or railways 71 to link the Yukon, northern British Columbia and Alaska to the “outside.” These schemes were motivated by economic interests, including mining, lumber and tourism concerns. During...... the 1920s and 1930s a small but vocal group of “builders” began to campaign for a highway, either a coastal or inland route, to improve the northwest’s economic base. With the impending threat of war in the late 1930s, there was an increasing awareness by the American and Canadian governments...... increasing military needs. The unexpected bombing of Pearl Harbour in December 1941 stimulated interest in the construction of the Alaska Highway by the American government. The U.S. Army Corps of Engineers selected a route based on the location of the NWSR airfields and the military needs for an alternative...

Nuclear and radiochemistry, 3rd edition

International Nuclear Information System (INIS)

Friedlander, G.; Kennedy, J.W.; Macias, E.S.; Miller, J.M.

1981-01-01

A broad coverage of radioactivity and nuclear phenomena fundamentals is presented, followed by discussions of applications in such fields as basic chemistry, biology, medicine, earth and space sciences. Following an introductory historical chapter, the basic fundamentals of nuclear properties, radioactive growth and decay, and nuclear reactions are covered in the first five chapters. Chapters 6-10 deal mainly with topics essential to the practicing radiochemist. They include discussion of interactions of radiation with matter, radiation detection and measurement, techniques in nuclear chemistry, statistics and radioactivity and nuclear models. Applications of these disciplines in the various fields noted above together with chapters on nuclear energy and sources of nuclear bombarding particles complete the 15 chapters of the book

Program for control and editing the output data of spiral reader

International Nuclear Information System (INIS)

Yamburenko, V.S.

1983-01-01

The program forming the magnetic tape with outpug data of Spiral Reader from that one containing initial data for computing on big computers is desribed. The program is controlled by ''operator-computer'' dialogue using the HT-340 display. During rewriting the data structure and quality are checked. Manual and automatic modes of rewriting are possible. The editing mode permits to create easily arrays of data of a given format. The magnetic tapes format and data structure are also described

High level of APOBEC3F/3G editing in HIV-2 DNA vif and pol sequences from antiretroviral-naive patients.

Science.gov (United States)

Bertine, Mélanie; Charpentier, Charlotte; Visseaux, Benoit; Storto, Alexandre; Collin, Gilles; Larrouy, Lucile; Damond, Florence; Matheron, Sophie; Brun-Vézinet, Françoise; Descamps, Diane

2015-04-24

In HIV-1, hypermutation introduced by APOBEC3F/3G cytidine deaminase activity leads to defective viruses. In-vivo impact of APOBEC3F/3G editing on HIV-2 sequences remains unknown. The objective of this study was to assess the level of APOBEC3F/3G editing in HIV-2-infected antiretroviral-naive patients. Direct sequencing of vif and pol regions was performed on HIV-2 proviral DNA from antiretroviral-naive patients included in the French Agence Nationale de Recherches sur le SIDA et les hépatites virales CO5 HIV-2 cohort. Hypermutated sequences were identified using Hypermut2.0 program. HIV-1 proviral sequences from Genbank were also assessed. Among 82 antiretroviral-naive HIV-2-infected patients assessed, 15 (28.8%) and five (16.7%) displayed Vif proviral defective sequences in HIV-2 groups A and B, respectively. A lower proportion of defective sequences was observed in protease-reverse transcriptase region. A higher median number of G-to-A mutations was observed in HIV-2 group B than in group A, both in Vif and protease-reverse transcriptase regions (P = 0.02 and P = 0.006, respectively). Compared with HIV-1 Vif sequences, a higher number of Vif defective sequences was observed in HIV-2 group A (P = 0.00001) and group B sequences (P = 0.013). We showed for the first time a high level of APOBEC3F/3G editing in HIV-2 sequences from antiretroviral-naive patients. Our study reported a group effect with a significantly higher level of APOBEC3F/3G editing in HIV-2 group B than in group A sequences.

3rd International Conference on Modelling, Computation and Optimization in Information Systems and Management Sciences

CERN Document Server

Dinh, Tao; Nguyen, Ngoc

2015-01-01

This proceedings set contains 85 selected full papers presented at the 3rd International Conference on Modelling, Computation and Optimization in Information Systems and Management Sciences - MCO 2015, held on May 11–13, 2015 at Lorraine University, France. The present part I of the 2 volume set includes articles devoted to Combinatorial optimization and applications, DC programming and DCA: thirty years of Developments, Dynamic Optimization, Modelling and Optimization in financial engineering, Multiobjective programming, Numerical Optimization, Spline Approximation and Optimization, as well as Variational Principles and Applications

User's guide of parallel program development environment (PPDE). The 2nd edition

International Nuclear Information System (INIS)

Ueno, Hirokazu; Takemiya, Hiroshi; Imamura, Toshiyuki; Koide, Hiroshi; Matsuda, Katsuyuki; Higuchi, Kenji; Hirayama, Toshio; Ohta, Hirofumi

2000-03-01

The STA basic system has been enhanced to accelerate support for parallel programming on heterogeneous parallel computers, through a series of R and D on the technology of parallel processing. The enhancement has been made through extending the function of the PPDF, Parallel Program Development Environment in the STA basic system. The extended PPDE has the function to make: 1) the automatic creation of a 'makefile' and a shell script file for its execution, 2) the multi-tools execution which makes the tools on heterogeneous computers to execute with one operation a task on a computer, and 3) the mirror composition to reflect editing results of a file on a computer into all related files on other computers. These additional functions will enhance the work efficiency for program development on some computers. More functions have been added to the PPDE to provide help for parallel program development. New functions were also designed to complement a HPF translator and a parallelizing support tool when working together so that a sequential program is efficiently converted to a parallel program. This report describes the use of extended PPDE. (author)

User's guide of parallel program development environment (PPDE). The 2nd edition

Energy Technology Data Exchange (ETDEWEB)

Ueno, Hirokazu; Takemiya, Hiroshi; Imamura, Toshiyuki; Koide, Hiroshi; Matsuda, Katsuyuki; Higuchi, Kenji; Hirayama, Toshio [Center for Promotion of Computational Science and Engineering, Japan Atomic Energy Research Institute, Tokyo (Japan); Ohta, Hirofumi [Hitachi Ltd., Tokyo (Japan)

2000-03-01

The STA basic system has been enhanced to accelerate support for parallel programming on heterogeneous parallel computers, through a series of R and D on the technology of parallel processing. The enhancement has been made through extending the function of the PPDF, Parallel Program Development Environment in the STA basic system. The extended PPDE has the function to make: 1) the automatic creation of a 'makefile' and a shell script file for its execution, 2) the multi-tools execution which makes the tools on heterogeneous computers to execute with one operation a task on a computer, and 3) the mirror composition to reflect editing results of a file on a computer into all related files on other computers. These additional functions will enhance the work efficiency for program development on some computers. More functions have been added to the PPDE to provide help for parallel program development. New functions were also designed to complement a HPF translator and a paralleilizing support tool when working together so that a sequential program is efficiently converted to a parallel program. This report describes the use of extended PPDE. (author)

Main results on pilot operation during 5 years of the 3rd generation fuel in VVER-440 reactors of Kola NPP

International Nuclear Information System (INIS)

Saprykin, V.; Sumarokov, M.; Gagarinskiy, A.; Sumarokova, A.; Adeev, V.

2015-01-01

In the report the results of comparison of main neutron-physical data of exploitation of nuclear fuel are presented for the average enrichment (on U - 235) of 4.87 for the 2nd and 3rd (12 piece) generations with the results of calculations by the complex of the programs KASKAD for 5 fuel loadings of Kola NPP Unit 4 with the reactor VVER- 440. The basic feature of fuel of the 3rd generation as compared with the 2nd is a presence of ribs of inflexibility at corners instead of cover of the fuel assembly and also the increased amount of uranium. The arrangement of fuel rods with different enrichment in fuel assemblies of the 2nd and 3rd generations is chosen identical for the convenient comparison of neutronic and thermohydraulic characteristics of the fuel of different generations. The fuel of 3rd generation was situated in the core symmetrically to the fuel of 2nd one

File list: InP.Lar.50.AllAg.3rd_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available InP.Lar.50.AllAg.3rd_instar dm3 Input control Larvae 3rd instar SRX287726,SRX331369...87917,SRX287921,SRX288023,SRX467107,SRX016172,SRX016173 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Lar.50.AllAg.3rd_instar.bed ...

Transcriptional regulation of ABI3- and ABA-responsive genes including RD29B and RD29A in seeds, germinating embryos, and seedlings of Arabidopsis.

Science.gov (United States)

Nakashima, Kazuo; Fujita, Yasunari; Katsura, Koji; Maruyama, Kyonoshin; Narusaka, Yoshihiro; Seki, Motoaki; Shinozaki, Kazuo; Yamaguchi-Shinozaki, Kazuko

2006-01-01

ABA-responsive elements (ABREs) are cis-acting elements and basic leucine zipper (bZIP)-type ABRE-binding proteins (AREBs) are transcriptional activators that function in the expression of RD29B in vegetative tissue of Arabidopsis in response to abscisic acid (ABA) treatment. Dehydration-responsive elements (DREs) function as coupling elements of ABRE in the expression of RD29A in response to ABA. Expression analysis using abi3 and abi5 mutants showed that ABI3 and ABI5 play important roles in the expression of RD29B in seeds. Base-substitution analysis showed that two ABREs function strongly and one ABRE coupled with DRE functions weakly in the expression of RD29A in embryos. In a transient transactivation experiment, ABI3, ABI5 and AREB1 activated transcription of a GUS reporter gene driven by the RD29B promoter strongly but these proteins activated the transcription driven by the RD29A promoter weakly. In 35S::ABI3 Arabidopsis plants, the expression of RD29B was up-regulated strongly, but that of RD29A was up-regulated weakly. These results indicate that the expression of RD29B having ABREs in the promoter is up-regulated strongly by ABI3, whereas that of RD29A having one ABRE coupled with DREs in the promoter is up-regulated weakly by ABI3. We compared the expression of 7000 Arabidopsis genes in response to ABA treatment during germination and in the vegetative growth stage, and that in 35S::ABI3 plants using a full-length cDNA microarray. The expression of ABI3- and/or ABA-responsive genes and cis-elements in the promoters are discussed.

File list: InP.Lar.20.AllAg.3rd_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: InP.Lar.10.AllAg.3rd_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: InP.Lar.05.AllAg.3rd_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

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Using Food as a Tool to Teach Science to 3rd Grade Students in Appalachian Ohio

Science.gov (United States)

Duffrin, Melani W.; Hovland, Jana; Carraway-Stage, Virginia; McLeod, Sara; Duffrin, Christopher; Phillips, Sharon; Rivera, David; Saum, Diana; Johanson, George; Graham, Annette; Lee, Tammy; Bosse, Michael; Berryman, Darlene

2010-01-01

The Food, Math, and Science Teaching Enhancement Resource (FoodMASTER) Initiative is a compilation of programs aimed at using food as a tool to teach mathematics and science. In 2007 to 2008, a foods curriculum developed by professionals in nutrition and education was implemented in 10 3rd-grade classrooms in Appalachian Ohio; teachers in these…

3rd International Conference on Transcriptomics

OpenAIRE

John A Daniel

2017-01-01

Conference Series has been instrumental in conducting international Biochemistry meetings for seven years, and very excited to expand Europe, America and Asia Pacific continents. Previous meetings were held in major cities like Philadelphia, Orlando with success the meetings again scheduled in three continents. 3rd International Conference on Transcriptomics to be held during October 30 - November 01, 2017 at Bangkok, Thailand The Global Transcriptomics business sector to develop at a C...

The 3rd power unit roofing decontamination

International Nuclear Information System (INIS)

Samojlenko, Yu.N.; Golubev, V.V.

1989-01-01

The most features of the 3rd power unit (PU) roofing decontamination are described: 1) the most active materials were thrown into the 4th PU ruins before the Ukrytie construction completion; 2) the decontamination was fulfilled using remote-controlled mechanisms and manual devices (the main part). 6 figs.; 1 tab

3rd Semester and Master's Thesis Ideas

DEFF Research Database (Denmark)

Clausen, Johan

The following pages contain a list of project ideas proposed by the scientific staff at the department of Civil Engineering, Aalborg University, and a number of companies. Most of the project ideas in this catalouge may form the basis for long and short candidate projects as well as regular 3rd...

Edit distance for marked point processes revisited: An implementation by binary integer programming

Energy Technology Data Exchange (ETDEWEB)

Hirata, Yoshito; Aihara, Kazuyuki [Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505 (Japan)

2015-12-15

We implement the edit distance for marked point processes [Suzuki et al., Int. J. Bifurcation Chaos 20, 3699–3708 (2010)] as a binary integer program. Compared with the previous implementation using minimum cost perfect matching, the proposed implementation has two advantages: first, by using the proposed implementation, we can apply a wide variety of software and hardware, even spin glasses and coherent ising machines, to calculate the edit distance for marked point processes; second, the proposed implementation runs faster than the previous implementation when the difference between the numbers of events in two time windows for a marked point process is large.

Entrepreneurship and Small Business : 3rd Asia-Pacific Edition

OpenAIRE

Schaper, Michael; Volery, Thierry; Weber, Paull; Lewis, Kate

2010-01-01

(See also PDF) PART 1 The nature of small business and entrepreneurship. CHAPTER 1 Entrepreneurship: definition and evolution. CHAPTER 2 The personality of entrepreneurs. CHAPTER 3 Creativity, innovation and entrepreneurship. CHAPTER 4 Small business: definitions and characteristics. PART 2 Getting into business. CHAPTER 5 Options for going into business. CHAPTER 6 Market research and strategy formulation. CHAPTER 7 Preparing a business plan. CHAPTER 7 ...

Second revised edition of JENDL-3 (JENDL-3,2)

International Nuclear Information System (INIS)

Kikuchi, Yasuyuki

1995-01-01

In Nuclear Data Center, Japan Atomic Energy Research Institute, the development of Japanese standard evaluated nuclear data library, JENDL, since the beginning of 1970s has been advanced. In June, 1994, the second revised edition of the third edition, JENDL-3,2, was opened to public. This JENDL-3,2 is expected to be utilized widely in Japan and abroad by freezing it for the time being as the final version of JENDL. This report is the contents of the publication of JENDL-3,2 of the title 'Present state of Japanese nuclear data activities' made at Physical Society of Japan in 1994. Nuclear data are divided into nuclear reaction data and nuclear structure data. The nuclear reaction data on neutron induction, evaluated nuclear data file and the international cooperation for nuclear data are described. The history of Japanese nuclear data activities, nuclear data libraries in the world and the history of JENDL are introduced. As for the evaluation of JENDL-3, its outline, light, medium and heavy nuclei, the nuclides of nuclear fission products, main actinide nuclides, transuranic elements and gamma ray generation data are reported. As for the bench mark test of JENDL-3,1, its outline, simple system bench mark, fast reactor system, thermal neutron reactor system, shield bench mark and feedback information from bench mark test are described. The evaluation and the bench mark test for LENDL-3,2 are reported. (K.I.)

CERES BiDirectional Scans (BDS) data in HDF (CER_BDS_Aqua-FM3_Edition1)

Science.gov (United States)

Wielicki, Bruce A. (Principal Investigator)

Each BiDirectional Scans (BDS) data product contains twenty-four hours of Level-1b data for each CERES scanner instrument mounted on each spacecraft. The BDS includes samples taken in normal and short Earth scan elevation profiles in both fixed and rotating azimuth scan modes (including space, internal calibration, and solar calibration views). The BDS contains Level-0 raw (unconverted) science and instrument data as well as the geolocated converted science and instrument data. The BDS contains additional data not found in the Level-0 input file, including converted satellite position and velocity data, celestial data, converted digital status data, and parameters used in the radiance count conversion equations. The following CERES BDS data sets are currently available: CER_BDS_TRMM-PFM_Edition1 CER_BDS_Terra-FM1_Edition1 CER_BDS_Terra-FM2_Edition1 CER_BDS_Terra-FM1_Edition2 CER_BDS_Terra-FM2_Edition2 CER_BDS_Aqua-FM3_Edition1 CER_BDS_Aqua-FM4_Edition1 CER_BDS_Aqua-FM3_Edition2 CER_BDS_Aqua-FM4_Edition2 CER_BDS_Aqua-FM3_Edition1-CV CER_BDS_Aqua-FM4_Edition1-CV CER_BDS_Terra-FM1_Edition1-CV CER_BDS_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2005-11-02] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

CERES BiDirectional Scans (BDS) data in HDF (CER_BDS_Aqua-FM3_Edition2)

Science.gov (United States)

Wielicki, Bruce A. (Principal Investigator)

Each BiDirectional Scans (BDS) data product contains twenty-four hours of Level-1b data for each CERES scanner instrument mounted on each spacecraft. The BDS includes samples taken in normal and short Earth scan elevation profiles in both fixed and rotating azimuth scan modes (including space, internal calibration, and solar calibration views). The BDS contains Level-0 raw (unconverted) science and instrument data as well as the geolocated converted science and instrument data. The BDS contains additional data not found in the Level-0 input file, including converted satellite position and velocity data, celestial data, converted digital status data, and parameters used in the radiance count conversion equations. The following CERES BDS data sets are currently available: CER_BDS_TRMM-PFM_Edition1 CER_BDS_Terra-FM1_Edition1 CER_BDS_Terra-FM2_Edition1 CER_BDS_Terra-FM1_Edition2 CER_BDS_Terra-FM2_Edition2 CER_BDS_Aqua-FM3_Edition1 CER_BDS_Aqua-FM4_Edition1 CER_BDS_Aqua-FM3_Edition2 CER_BDS_Aqua-FM4_Edition2 CER_BDS_Aqua-FM3_Edition1-CV CER_BDS_Aqua-FM4_Edition1-CV CER_BDS_Terra-FM1_Edition1-CV CER_BDS_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2006-01-01] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

Transcripts of the NADH-dehydrogenase subunit 3 gene are differentially edited in Oenothera mitochondria.

Science.gov (United States)

Schuster, W; Wissinger, B; Unseld, M; Brennicke, A

1990-01-01

A number of cytosines are altered to be recognized as uridines in transcripts of the nad3 locus in mitochondria of the higher plant Oenothera. Such nucleotide modifications can be found at 16 different sites within the nad3 coding region. Most of these alterations in the mRNA sequence change codon identities to specify amino acids better conserved in evolution. Individual cDNA clones differ in their degree of editing at five nucleotide positions, three of which are silent, while two lead to codon alterations specifying different amino acids. None of the cDNA clones analysed is maximally edited at all possible sites, suggesting slow processing or lowered stringency of editing at these nucleotides. Differentially edited transcripts could be editing intermediates or could code for differing polypeptides. Two edited nucleotides in an open reading frame located upstream of nad3 change two amino acids in the deduced polypeptide. Part of the well-conserved ribosomal protein gene rps12 also encoded downstream of nad3 in other plants, is lost in Oenothera mitochondria by recombination events. The functional rps12 protein must be imported from the cytoplasm since the deleted sequences of this gene are not found in the Oenothera mitochondrial genome. The pseudogene sequence is not edited at any nucleotide position. Images Fig. 3. Fig. 4. Fig. 7. PMID:1688531

3rd Interplanetary Network Gamma-Ray Burst Website

Science.gov (United States)

Hurley, Kevin

1998-05-01

We announce the opening of the 3rd Interplanetary Network web site at http://ssl.berkeley.edu/ipn3/index.html This site presently has four parts: 1. A bibliography of over 3000 publications on gamma-ray bursts, 2. IPN data on all bursts triangulated up to February 1998, 3. A master list showing which spacecraft observed which bursts, 4. Preliminary IPN data on the latest bursts observed.

Fusion Canada issue 32. Final edition

International Nuclear Information System (INIS)

1997-07-01

Fusion Canada is a bulletin of the National Fusion Program, this is the last edition. Included in this July edition are articles on Funding for Canada's fusion program, Research and Development on TdeV-96 , Divertor Maintenance Robotics and reference listing for Canada's Fusion research and development sites

Exercises in statistics for HA & HA(dat.) & BSc(B), 3rd semester

DEFF Research Database (Denmark)

The booklet contains excercises to be used for the tutorials related to the 3rd semester course in statistics on the bachelors progarmme at the Aarhus School of Business.......The booklet contains excercises to be used for the tutorials related to the 3rd semester course in statistics on the bachelors progarmme at the Aarhus School of Business....

Operation results of 3-rd generation nuclear fuel WWER-440 in initial period

International Nuclear Information System (INIS)

Adeev, V.; Panov, A.

2011-01-01

On unit 4 of Kola NPP trial operation of 3-rd generation's fuel began in 2010. Fuel assemblies of 3-rd generation (FA-3) have a number of design features that provide better operational characteristics. Concise description of a design and the basic advantages of fuel of 3-rd generation are described in articles. Increasing of efficiency of nuclear fuel usage will be achieved by reduction of the parasitic capture of thermal neutrons in constructional materials (weight of zirconium is reduced), optimization of uranium-water relation (increase in fuel elements step), increasing of uranium loading (usage of fuel pellets with increased diameter and without central hole in them). By results of trial operation mass transition to use of given type of assemblies in WWER-440 is possible. This report presents the basic outcomes of the trial operation, a brief survey of the obtained data. The basic characteristics of the reactor core with fuel of 3-rd generation are resulted in work. (authors)

LabVIEW 8 student edition

CERN Document Server

Bishop, Robert H

2007-01-01

For courses in Measurement and Instrumentation, Electrical Engineering lab, and Physics and Chemistry lab. This revised printing has been updated to include new LabVIEW 8.2 Student Edition. National Instruments' LabVIEW is the defacto industry standard for test, measurement, and automation software solutions. With the Student Edition of LabVIEW, students can design graphical programming solutions to their classroom problems and laboratory experiments with software that delivers the graphical programming capabilites of the LabVIEW professional version. . The Student Edition is also compatible with all National Instruments data acquisition and instrument control hardware. Note: The LabVIEW Student Edition is available to students, faculty, and staff for personal educational use only. It is not intended for research, institutional, or commercial use. For more information about these licensing options, please visit the National Instruments website at (http:www.ni.com/academic/)

The Montana Rivers Information System: Edit/entry program user`s manual

Energy Technology Data Exchange (ETDEWEB)

1992-07-01

The Montana Rivers Information System (MRIS) was initiated to assess the state`s fish, wildlife, and recreation value; and natural cultural and geologic features. The MRIS is now a set of data bases containing part of the information in the Natural Heritage Program natural features and threatened and endangered species data bases. The purpose of this User`s Manual is to: (1) describe to the user how to maintain the MRIS database of their choice by updating, changing, deleting, and adding records using the edit/entry programs; and (2) provide to the user all information and instructions necessary to complete data entry into the MRIS databases.

User's guide of parallel program development environment (PPDE). The 2nd edition

Energy Technology Data Exchange (ETDEWEB)

Ueno, Hirokazu; Takemiya, Hiroshi; Imamura, Toshiyuki; Koide, Hiroshi; Matsuda, Katsuyuki; Higuchi, Kenji; Hirayama, Toshio [Center for Promotion of Computational Science and Engineering, Japan Atomic Energy Research Institute, Tokyo (Japan); Ohta, Hirofumi [Hitachi Ltd., Tokyo (Japan)

2000-03-01

The STA basic system has been enhanced to accelerate support for parallel programming on heterogeneous parallel computers, through a series of R and D on the technology of parallel processing. The enhancement has been made through extending the function of the PPDF, Parallel Program Development Environment in the STA basic system. The extended PPDE has the function to make: 1) the automatic creation of a 'makefile' and a shell script file for its execution, 2) the multi-tools execution which makes the tools on heterogeneous computers to execute with one operation a task on a computer, and 3) the mirror composition to reflect editing results of a file on a computer into all related files on other computers. These additional functions will enhance the work efficiency for program development on some computers. More functions have been added to the PPDE to provide help for parallel program development. New functions were also designed to complement a HPF translator and a paralleilizing support tool when working together so that a sequential program is efficiently converted to a parallel program. This report describes the use of extended PPDE. (author)

The operation of a Research and Development (R&D) program and its significance for practice change in community pharmacy.

Science.gov (United States)

Hermansyah, Andi; Sainsbury, Erica; Krass, Ines

2017-01-01

Community pharmacy practice in Australia is changing and Research and Development (R&D) in community pharmacy plays an important role in contributing to the changes. A range of Cognitive Pharmacy Services (CPS) were developed from R&D programs, yet their implementation has been minimal indicating slow practice change within community pharmacy. Given the vital role of R&D, little is known about the operation and the extent to which it has been effective in supporting practice change in community pharmacy. In depth, semi-structured interviews were conducted with 27 key stakeholders in the pharmacy and healthcare system in Australia. All interviews were audio-recorded, transcribed ad verbatim and analysed using an inductive approach. Participants perceived that the R&D program has played an important role in the advent of CPS. Furthermore, they considered that evidence generated by the R&D projects is a critical influence on policy formulation, funding and implementation of CPS into practice. However, policy decisions and subsequent implementation are also influenced by other factors associated with context and facilitation which in turn foster or inhibit effective Knowledge Translation (KT) in the community pharmacy sector. While R&D programs have been viewed as essential for supporting changes in community pharmacy practice through development and funding of CPS, the overall impact has been small, as contemporary practice continues to be predominantly a dispensing model. Given the complexity and dynamic nature of the community pharmacy system, stakeholders must take into account the inter-relationship between context, evidence and facilitation for successful KT in community pharmacy practice.

The INFN-FBK pixel R&D program for HL-LHC

Science.gov (United States)

Meschini, M.; Dalla Betta, G. F.; Boscardin, M.; Calderini, G.; Darbo, G.; Giacomini, G.; Messineo, A.; Ronchin, S.

2016-09-01

We report on the ATLAS and CMS joint research activity, which is aiming at the development of new, thin silicon pixel detectors for the Large Hadron Collider Phase-2 detector upgrades. This R&D is performed under special agreement between Istituto Nazionale di Fisica Nucleare and FBK foundation (Trento, Italy). New generations of 3D and planar pixel sensors with active edges are being developed in the R&D project, and will be fabricated at FBK. A first planar pixel batch, which was produced by the end of year 2014, will be described in this paper. First clean room measurement results on planar sensors obtained before and after neutron irradiation will be presented.

The INFN-FBK pixel R&D program for HL-LHC

International Nuclear Information System (INIS)

Meschini, M.; Dalla Betta, G.F.; Boscardin, M.; Calderini, G.; Darbo, G.; Giacomini, G.; Messineo, A.; Ronchin, S.

2016-01-01

We report on the ATLAS and CMS joint research activity, which is aiming at the development of new, thin silicon pixel detectors for the Large Hadron Collider Phase-2 detector upgrades. This R&D is performed under special agreement between Istituto Nazionale di Fisica Nucleare and FBK foundation (Trento, Italy). New generations of 3D and planar pixel sensors with active edges are being developed in the R&D project, and will be fabricated at FBK. A first planar pixel batch, which was produced by the end of year 2014, will be described in this paper. First clean room measurement results on planar sensors obtained before and after neutron irradiation will be presented.

The assembly of F1FO-ATP synthase is disrupted upon interference of RNA editing in Trypanosoma brucei

Czech Academy of Sciences Publication Activity Database

Hashimi, Hassan; Benkovičová, V.; Čermáková, P.; Lai, De Hua; Horváth, A.; Lukeš, Julius

2010-01-01

Roč. 40, č. 1 (2010), s. 45-54 ISSN 0020-7519 R&D Projects: GA ČR GA204/06/1558; GA AV ČR IAA500960705 Institutional research plan: CEZ:AV0Z60220518 Keywords : RNA editing * ATP synthase * mitochondrion * Trypanosoma * respiratory complex * membrane potential Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 3.822, year: 2010

Book of abstracts of the 3rd International conference and the 3rd International School for young scientists Interaction of hydrogen isotopes with structural materials. IHISM-07

International Nuclear Information System (INIS)

2007-01-01

The book involves abstracts of presentations at the 3rd International Conference and the 3rd International School for Young Scientists Interaction of Hydrogen Isotopes with Structural Materials (IHISM-07). The activities of Russian and foreign scientific centers associated with the use of hydrogen isotopes in power engineering, national economy and basic research are considered. The presentations cover the following areas: kinetics and interaction between hydrogen isotopes and solids including effects of radiogenic helium accumulation, hydrides and hydride transformations; structural transformations and mechanical properties; equipment and research techniques [ru

Magnet Free Generators - 3rd Generation Wind Turbine Generators

DEFF Research Database (Denmark)

Jensen, Bogi Bech; Mijatovic, Nenad; Henriksen, Matthew Lee

2013-01-01

This paper presents an introduction to superconducting wind turbine generators, which are often referred to as 3rd generation wind turbine generators. Advantages and challenges of superconducting generators are presented with particular focus on possible weight and efficiency improvements. A comp...

CERES ERBE-like Instantaneous TOA Estimates (ES-8) in HDF (CER_ES8_Aqua-FM3_Edition2)

Science.gov (United States)

Wielicki, Bruce A. (Principal Investigator)

The ES-8 archival data product contains a 24-hour, single-satellite, instantaneous view of scanner fluxes at the top-of-atmosphere (TOA) reduced from spacecraft altitude unfiltered radiances using Earth Radiation Budget Experiment (ERBE) scanner Inversion algorithms and the ERBE shortwave (SW) and longwave (LW) Angular Distribution Models (ADMs). The ES-8 also includes the total (TOT), SW, LW, and window (WN) channel radiometric data; SW, LW, and WN unfiltered radiance values; and the ERBE scene identification for each measurement. These data are organized according to the CERES 3.3-second scan into 6.6-second records. As long as there is one valid scanner measurement within a record, the ES-8 record will be generated. The following CERES ES8 data sets are currently available: CER_ES8_TRMM-PFM_Edition1 CER_ES8_TRMM-PFM_Edition2 CER_ES8_TRMM-PFM_Transient-Ops2 CER_ES8_Terra-FM1_Edition1 CER_ES8_Terra-FM2_Edition1 CER_ES8_Terra-FM1_Edition2 CER_ES8_Terra-FM2_Edition2 CER_ES8_Aqua-FM3_Edition1 CER_ES8_Aqua-FM4_Edition1 CER_ES8_Aqua-FM3_Edition2 CER_ES8_Aqua-FM4_Edition2 CER_ES8_Aqua-FM3_Edition1-CV CER_ES8_Aqua-FM4_Edition1-CV CER_ES8_Terra-FM1_Edition1-CV CER_ES8_Terra-FM1_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2005-12-31] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

3rd MeTrApp Conference

CERN Document Server

Lovasz, Erwin-Christian; Hüsing, Mathias

2015-01-01

This volume deals with topics such as mechanism and machine design, biomechanics and medical engineering, gears, mechanical transmissions, mechatronics, computational and experimental methods, dynamics of mechanisms and machines, micromechanisms and microactuators, and history of mechanisms and transmissions. Following MeTrApp 2011 and 2013, held under the auspices of the IFToMM, these proceedings of the 3rd Conference on Mechanisms, Transmissions and Applications offer a platform for original research presentations for researchers, scientists, industry experts and students in the fields of mechanisms and transmissions with special emphasis on industrial applications in order to stimulate the exchange of new and innovative ideas.

FY2016 Advanced Batteries R&D Annual Progress Report - Part 3 of 5

Energy Technology Data Exchange (ETDEWEB)

None, None

2017-08-31

The Advanced Batteries research and development (R&D) subprogram within the DOE Vehicle Technologies Office (VTO) provides support and guidance for projects focusing on batteries for plug-in electric vehicles. Program targets focus on overcoming technical barriers to enable market success including: (1) significantly reducing battery cost, (2) increasing battery performance (power, energy, durability), (3) reducing battery weight & volume, and (4) increasing battery tolerance to abusive conditions such as short circuit, overcharge, and crush. This report describes the progress made on the research and development projects funded by the Battery subprogram in 2016. This section covers the summaries of the Applied Batteries Research for Transportation Projects part 2.

Revising the ACS Guidelines for Chemistry Programs in Two-Year Colleges: Shaping the Next Edition

Science.gov (United States)

Clevenger, John V.; Wesemann, Jodi L.

2008-06-01

Much has changed since the second edition of the ACS Guidelines for Chemistry Programs in Two-Year Colleges was prepared in 1997. The roles that two-year college programs can and do play in providing access to and success in higher education are receiving more attention. Increased knowledge on how people learn, advances in technology, and demands for accountability are changing the educational landscape.

CERES ERBE-like Monthly Geographical Averages (ES-4) in HDF (CER_ES4_Aqua-FM3_Edition1)

Science.gov (United States)

Wielicki, Bruce A. (Principal Investigator)

The ERBE-like Monthly Geographical Averages (ES-4) product contains a month of space and time averaged Clouds and the Earth's Radiant Energy System (CERES) data for a single scanner instrument. The ES-4 is also produced for combinations of scanner instruments. For each observed 2.5-degree spatial region, the daily average, the hourly average over the month, and the overall monthly average of shortwave and longwave fluxes at the Top-of-the-Atmosphere (TOA) from the CERES ES-9 product are spatially nested up from 2.5-degree regions to 5- and 10-degree regions, to 2.5-, 5-, and 10-degree zonal averages, and to global monthly averages. For each nested area, the albedo and net flux are given. For each region, the daily average flux is estimated from an algorithm that uses the available hourly data, scene identification data, and diurnal models. This algorithm is 'like' the algorithm used for the Earth Radiation Budget Experiment (ERBE). The following CERES ES4 data sets are currently available: CER_ES4_FM1+FM2_Edition1 CER_ES4_PFM+FM1+FM2_Edition1 CER_ES4_PFM+FM1+FM2_Edition2 CER_ES4_PFM+FM1_Edition1 CER_ES4_PFM+FM2_Edition1 CER_ES4_TRMM-PFM_Edition1 CER_ES4_TRMM-PFM_Edition2 CER_ES4_Terra-FM1_Edition1 CER_ES4_Terra-FM2_Edition1 CER_ES4_FM1+FM2_Edition2 CER_ES4_Terra-FM1_Edition2 CER_ES4_Terra-FM2_Edition2 CER_ES4_Aqua-FM3_Edition1 CER_ES4_Aqua-FM4_Edition1 CER_ES4_FM1+FM2+FM3+FM4_Edition1 CER_ES4_Aqua-FM3_Edition2 CER_ES4_Aqua-FM4_Edition2 CER_ES4_FM1+FM3_Edition2 CER_ES4_FM1+FM4_Edition2 CER_ES4_PFM+FM1_Edition2 CER_ES4_PFM+FM2_Edition2 CER_ES4_Aqua-FM3_Edition1-CV CER_ES4_Aqua-FM4_Edition1-CV CER_ES4_Terra-FM1_Edition1-CV CER_ES4_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1998-01-01; Stop_Date=2005-10-31] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Latitude_Resolution=2.5 degree; Longitude_Resolution=2.5 degree; Horizontal

CERES ERBE-like Monthly Geographical Averages (ES-4) in HDF (CER_ES4_Aqua-FM3_Edition2)

Science.gov (United States)

Wielicki, Bruce A. (Principal Investigator)

The ERBE-like Monthly Geographical Averages (ES-4) product contains a month of space and time averaged Clouds and the Earth's Radiant Energy System (CERES) data for a single scanner instrument. The ES-4 is also produced for combinations of scanner instruments. For each observed 2.5-degree spatial region, the daily average, the hourly average over the month, and the overall monthly average of shortwave and longwave fluxes at the Top-of-the-Atmosphere (TOA) from the CERES ES-9 product are spatially nested up from 2.5-degree regions to 5- and 10-degree regions, to 2.5-, 5-, and 10-degree zonal averages, and to global monthly averages. For each nested area, the albedo and net flux are given. For each region, the daily average flux is estimated from an algorithm that uses the available hourly data, scene identification data, and diurnal models. This algorithm is 'like' the algorithm used for the Earth Radiation Budget Experiment (ERBE). The following CERES ES4 data sets are currently available: CER_ES4_FM1+FM2_Edition1 CER_ES4_PFM+FM1+FM2_Edition1 CER_ES4_PFM+FM1+FM2_Edition2 CER_ES4_PFM+FM1_Edition1 CER_ES4_PFM+FM2_Edition1 CER_ES4_TRMM-PFM_Edition1 CER_ES4_TRMM-PFM_Edition2 CER_ES4_Terra-FM1_Edition1 CER_ES4_Terra-FM2_Edition1 CER_ES4_FM1+FM2_Edition2 CER_ES4_Terra-FM1_Edition2 CER_ES4_Terra-FM2_Edition2 CER_ES4_Aqua-FM3_Edition1 CER_ES4_Aqua-FM4_Edition1 CER_ES4_FM1+FM2+FM3+FM4_Edition1 CER_ES4_Aqua-FM3_Edition2 CER_ES4_Aqua-FM4_Edition2 CER_ES4_FM1+FM3_Edition2 CER_ES4_FM1+FM4_Edition2 CER_ES4_PFM+FM1_Edition2 CER_ES4_PFM+FM2_Edition2 CER_ES4_Aqua-FM3_Edition1-CV CER_ES4_Aqua-FM4_Edition1-CV CER_ES4_Terra-FM1_Edition1-CV CER_ES4_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1998-01-01; Stop_Date=2005-12-31] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Latitude_Resolution=2.5 degree; Longitude_Resolution=2.5 degree; Horizontal

Proceedings of the 3rd Symposium on Laser Spectroscopy

International Nuclear Information System (INIS)

1995-11-01

This proceedings contains articles of the 3rd Symposium on Laser Spectroscopy. It was held on Nov 10-11, 1995 in Taejeon, Korea. The main topics are as follows: Laser Isotope, Laser Spectroscopy, Laser Fusion, Laser Applications and so on. (Yi, J. H.)

Buildings R&D Breakthroughs. Technologies and Products Supported by the Building Technologies Program

Energy Technology Data Exchange (ETDEWEB)

none,

2012-04-01

This report identifies and characterizes commercially available products and emerging (near-commercial) technologies that benefited from the support of the Building Technologies Program (BTP) within the U.S. Department of Energy’s Office of Energy Efficiency and Renewable Energy. The investigation specifically focused on technology-oriented research and development (R&D) projects sponsored by BTP’s Emerging Technologies subprogram from 2005-2009.

3rd International Conference on Computer & Communication Technologies

CERN Document Server

Bhateja, Vikrant; Raju, K; Janakiramaiah, B

2017-01-01

The book is a compilation of high-quality scientific papers presented at the 3rd International Conference on Computer & Communication Technologies (IC3T 2016). The individual papers address cutting-edge technologies and applications of soft computing, artificial intelligence and communication. In addition, a variety of further topics are discussed, which include data mining, machine intelligence, fuzzy computing, sensor networks, signal and image processing, human-computer interaction, web intelligence, etc. As such, it offers readers a valuable and unique resource.

Chondromyxoid fibroma of distal 1/3 rd of fibula a rare tumour at rare ...

African Journals Online (AJOL)

Chondromyxoid fibromas are rare, benign tumours account for <1% of primary bone neoplasms. Most commonly affected in 2nd and 3rdof life. We report one such case of chondromyxoid fibroma in distal fibula of a 15-year-old girl. The patient was managed with lower 3rd fibulectomy and fibular turnoplasty from middle 3rd ...

CERES ERBE-like Monthly Regional Averages (ES-9) in HDF (CER_ES9_Aqua-FM3_Edition1)

Science.gov (United States)

Wielicki, Bruce A. (Principal Investigator)

The ERBE-like Monthly Regional Averages (ES-9) product contains a month of space and time averaged Clouds and the Earth's Radiant Energy System (CERES) data for a single scanner instrument. The ES-9 is also produced for combinations of scanner instruments. All instantaneous shortwave and longwave fluxes at the Top-of-the-Atmosphere (TOA) from the CERES ES-8 product for a month are sorted by 2.5-degree spatial regions, by day number, and by the local hour of observation. The mean of the instantaneous fluxes for a given region-day-hour bin is determined and recorded on the ES-9 along with other flux statistics and scene information. For each region, the daily average flux is estimated from an algorithm that uses the available hourly data, scene identification data, and diurnal models. This algorithm is 'like' the algorithm used for the Earth Radiation Budget Experiment (ERBE). The ES-9 also contains hourly average fluxes for the month and an overall monthly average for each region. These average fluxes are given for both clear-sky and total-sky scenes. The following CERES ES9 data sets are currently available: CER_ES9_FM1+FM2_Edition1 CER_ES9_PFM+FM1+FM2_Edition1 CER_ES9_PFM+FM1+FM2_Edition2 CER_ES9_PFM+FM1_Edition1 CER_ES9_PFM+FM2_Edition1 CER_ES9_PFM+FM1_Edition2 CER_ES9_PFM+FM2_Edition2 CER_ES9_TRMM-PFM_Edition1 CER_ES9_TRMM-PFM_Edition2 CER_ES9_Terra-FM1_Edition1 CER_ES9_Terra-FM2_Edition1 CER_ES9_FM1+FM2_Edition2 CER_ES9_Terra-FM1_Edition2 CER_ES9_Terra-FM2_Edition2 CER_ES9_Aqua-FM3_Edition1 CER_ES9_Aqua-FM4_Edition1 CER_ES9_FM1+FM2+FM3+FM4_Edition1 CER_ES9_Aqua-FM3_Edition2 CER_ES9_Aqua-FM4_Edition2 CER_ES9_FM1+FM3_Edition2 CER_ES9_FM1+FM4_Edition2 CER_ES9_Aqua-FM3_Edition1-CV CER_ES9_Aqua-FM4_Edition1-CV CER_ES9_Terra-FM1_Edition1-CV CER_ES9_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1998-01-01; Stop_Date=2005-10-31] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost

A Comparison of Low IQ Scores from the Reynolds Intellectual Assessment Scales and the Wechsler Adult Intelligence Scale--Third Edition

Science.gov (United States)

Umphress, Thomas B.

2008-01-01

Twenty people with suspected intellectual disability took the Reynolds Intellectual Assessment Scales (RIAS; C. R. Reynolds & R. W. Kamphaus, 1998) and the Wechsler Adult Intelligence Scale--3rd Edition (WAIS-III; D. Wechsler, 1997) to see if the 2 IQ tests produced comparable results. A t test showed that the RIAS Composite Intelligence Index…

Montana Rivers Information System : Edit/Entry Program User's Manual.

Energy Technology Data Exchange (ETDEWEB)

United States. Bonneville Power Administration; Montana Department of Fish, Wildlife and Parks

1992-07-01

The Montana Rivers Information System (MRIS) was initiated to assess the state`s fish, wildlife, and recreation value; and natural cultural, and geologic features. The MRIS is now a set of data bases containing part of the information in the Natural Heritage Program natural features and threatened and endangered species data bases and comprises of the Montana Interagency Stream Fisheries Database; the MDFWP Recreation Database; and the MDFWP Wildlife Geographic Information System. The purpose of this User`s Manual is to describe to the user how to maintain the MRIS database of their choice by updating, changing, deleting, and adding records using the edit/entry programs; and to provide to the user all information and instructions necessary to complete data entry into the MRIS databases.

The Oil Security Metrics Model: A Tool for Evaluating the Prospective Oil Security Benefits of DOE's Energy Efficiency and Renewable Energy R&D Programs

Energy Technology Data Exchange (ETDEWEB)

Greene, David L [ORNL; Leiby, Paul Newsome [ORNL

2006-05-01

Energy technology R&D is a cornerstone of U.S. energy policy. Understanding the potential for energy technology R&D to solve the nation's energy problems is critical to formulating a successful R&D program. In light of this, the U.S. Congress requested the National Research Council (NRC) to undertake both retrospective and prospective assessments of the Department of Energy's (DOE's) Energy Efficiency and Fossil Energy Research programs (NRC, 2001; NRC, 2005). ("The Congress continued to express its interest in R&D benefits assessment by providing funds for the NRC to build on the retrospective methodology to develop a methodology for assessing prospective benefits." NRC, 2005, p. ES-2) In 2004, the NRC Committee on Prospective Benefits of DOE's Energy Efficiency and Fossil Energy R&D Programs published a report recommending a new framework and principles for prospective benefits assessment. The Committee explicitly deferred the issue of estimating security benefits to future work. Recognizing the need for a rigorous framework for assessing the energy security benefits of its R&D programs, the DOE's Office of Energy Efficiency and Renewable Energy (EERE) developed a framework and approach for defining energy security metrics for R&D programs to use in gauging the energy security benefits of their programs (Lee, 2005). This report describes methods for estimating the prospective oil security benefits of EERE's R&D programs that are consistent with the methodologies of the NRC (2005) Committee and that build on Lee's (2005) framework. Its objective is to define and implement a method that makes use of the NRC's typology of prospective benefits and methodological framework, satisfies the NRC's criteria for prospective benefits evaluation, and permits measurement of that portion of the prospective energy security benefits of EERE's R&D portfolio related to oil. While the Oil Security Metrics (OSM) methodology described

Simultaneous measurement of Aspartate, NAA, and NAAG using HERMES spectral editing at 3 Tesla.

Science.gov (United States)

Chan, Kimberly L; Saleh, Muhammad G; Oeltzschner, Georg; Barker, Peter B; Edden, Richard A E

2017-07-15

It has previously been shown that the HERMES method ('Hadamard Encoding and Reconstruction of MEGA-Edited Spectroscopy') can be used to simultaneously edit pairs of metabolites (such as N-acetyl-aspartate (NAA) and N-acetyl aspartyl glutamate (NAAG), or glutathione and GABA). In this study, HERMES is extended for the simultaneous editing of three overlapping signals, and illustrated for the example of NAA, NAAG and Aspartate (Asp). Density-matrix simulations were performed in order to optimize the HERMES sequence. The method was tested in NAA and Asp phantoms, and applied to the centrum semiovale of the nine healthy control subjects that were scanned at 3T. Both simulations and phantom experiments showed similar metabolite multiplet patterns with good segregation of all three metabolites. In vivo measurements show consistent relative signal intensities and multiplet patterns with concentrations in agreement with literature values. Simulations indicate co-editing of glutathione, glutamine, and glutamate, but their signals do not significantly overlap with the detected aspartyl resonances. This study demonstrates that a four-step Hadamard-encoded editing scheme can be used to simultaneously edit three otherwise overlapping metabolites, and can measure NAA, NAAG, and Asp in vivo in the brain at 3T with minimal crosstalk. Copyright © 2017 Elsevier Inc. All rights reserved.

Teaching Technical Writing and Editing -- In-House Programs That Work. Anthology Series No. 5.

Science.gov (United States)

Shaw, James G., Ed.

The 12 articles in this publication provide indepth treatment of important aspects of in-house training programs for technical writing and editing. The articles deal with the following topics: the value of an in-house writing course, teaching in industry, developing an in-house writing course for engineers and scientists, a new approach to…

Mechanical design and engineering of the 3.9 GHZ, 3rd harmonic SRF system at Fermilab

International Nuclear Information System (INIS)

Don Mitchell

2004-01-01

The mechanical development of the 3.9 GHz, 3rd Harmonic SRF System is summarized to include: the development of a full scale copper prototype cavity structure; the design of the niobium 3 cell and niobium 9 cell structures; the design of the helium vessel and cryostat; the HOM coupler design; and a preliminary look at the main coupler design. The manufacturing processes for forming, rolling, and e-beam welding the HOM coupler, cavity cells, and end tubes are also described. Due to the exotic materials and manufacturing processes used in this type of device, a cost estimate for the material and fabrication is provided. The 3rd harmonic design is organized via a web-based data management approach

Mechanical design and engineering of the 3.9 GHZ, 3rd harmonic SRF system at Fermilab

Energy Technology Data Exchange (ETDEWEB)

Don Mitchell et al.

2004-08-05

The mechanical development of the 3.9 GHz, 3rd Harmonic SRF System is summarized to include: the development of a full scale copper prototype cavity structure; the design of the niobium 3 cell and niobium 9 cell structures; the design of the helium vessel and cryostat; the HOM coupler design; and a preliminary look at the main coupler design. The manufacturing processes for forming, rolling, and e-beam welding the HOM coupler, cavity cells, and end tubes are also described. Due to the exotic materials and manufacturing processes used in this type of device, a cost estimate for the material and fabrication is provided. The 3rd harmonic design is organized via a web-based data management approach.

The Child Sport Concussion Assessment Tool 5th Edition (Child SCAT5): Background and rationale.

Science.gov (United States)

Davis, Gavin A; Purcell, Laura; Schneider, Kathryn J; Yeates, Keith Owen; Gioia, Gerard A; Anderson, Vicki; Ellenbogen, Richard G; Echemendia, Ruben J; Makdissi, Michael; Sills, Allen; Iverson, Grant L; Dvořák, Jiří; McCrory, Paul; Meeuwisse, Willem; Patricios, Jon; Giza, Christopher C; Kutcher, Jeffrey S

2017-06-01

This article presents the Child Sport Concussion Assessment Tool 5th Edition (Child SCAT5). The Sport Concussion Assessment Tool was introduced in 2004, following the 2nd International Conference on Concussion in Sport in Prague, Czech Republic. Following the 4th International Consensus Conference, held in Zurich, Switzerland, in 2012, the SCAT 3rd edition (Child SCAT3) was developed for children aged between 5 and12 years. Research to date was reviewed and synthesised for the 5th International Consensus Conference on Concussion in Sport in Berlin, Germany, leading to the current revision of the test, the Child SCAT5. This article describes the development of the Child SCAT5. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

CERES ERBE-like Monthly Geographical Averages (ES-4) in HDF (CER_ES4_FM1+FM3_Edition2)

Science.gov (United States)

Wielicki, Bruce A. (Principal Investigator)

The ERBE-like Monthly Geographical Averages (ES-4) product contains a month of space and time averaged Clouds and the Earth's Radiant Energy System (CERES) data for a single scanner instrument. The ES-4 is also produced for combinations of scanner instruments. For each observed 2.5-degree spatial region, the daily average, the hourly average over the month, and the overall monthly average of shortwave and longwave fluxes at the Top-of-the-Atmosphere (TOA) from the CERES ES-9 product are spatially nested up from 2.5-degree regions to 5- and 10-degree regions, to 2.5-, 5-, and 10-degree zonal averages, and to global monthly averages. For each nested area, the albedo and net flux are given. For each region, the daily average flux is estimated from an algorithm that uses the available hourly data, scene identification data, and diurnal models. This algorithm is 'like' the algorithm used for the Earth Radiation Budget Experiment (ERBE). The following CERES ES4 data sets are currently available: CER_ES4_FM1+FM2_Edition1 CER_ES4_PFM+FM1+FM2_Edition1 CER_ES4_PFM+FM1+FM2_Edition2 CER_ES4_PFM+FM1_Edition1 CER_ES4_PFM+FM2_Edition1 CER_ES4_TRMM-PFM_Edition1 CER_ES4_TRMM-PFM_Edition2 CER_ES4_Terra-FM1_Edition1 CER_ES4_Terra-FM2_Edition1 CER_ES4_FM1+FM2_Edition2 CER_ES4_Terra-FM1_Edition2 CER_ES4_Terra-FM2_Edition2 CER_ES4_Aqua-FM3_Edition1 CER_ES4_Aqua-FM4_Edition1 CER_ES4_FM1+FM2+FM3+FM4_Edition1 CER_ES4_Aqua-FM3_Edition2 CER_ES4_Aqua-FM4_Edition2 CER_ES4_FM1+FM3_Edition2 CER_ES4_FM1+FM4_Edition2 CER_ES4_PFM+FM1_Edition2 CER_ES4_PFM+FM2_Edition2 CER_ES4_Aqua-FM3_Edition1-CV CER_ES4_Aqua-FM4_Edition1-CV CER_ES4_Terra-FM1_Edition1-CV CER_ES4_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1998-01-01; Stop_Date=2005-12-31] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Latitude_Resolution=2.5 degree; Longitude_Resolution=2.5 degree; Horizontal

Honors Programs at Smaller Colleges. 3rd Edition. National Collegiate Honors Council Monograph Series

Science.gov (United States)

Schuman, Samuel

2011-01-01

This monograph focuses upon areas of special concern to those working with honors at smaller colleges and universities: mission, recruitment, facilities, administration, budget, and curriculum. In each area, the author makes some general suggestions about overall operating principles, note specific issues that can lead to difficulties, and suggest…

3rd Semester and Master’s Thesis Ideas 2011

DEFF Research Database (Denmark)

The report contain a list of project ideas proposed by the scientific staff at the Department of Civil Engineering, Aalborg University, and a number of companies. Most of the project ideas in this catalogue may form the basis for long and short candidate projects as well as regular 3rd semester...

3rd Semester and Master’s Thesis Ideas 2013

DEFF Research Database (Denmark)

The following pages contain a list of project ideas proposed by the scientific staff at the Department of Civil Engineering, Aalborg University, and a number of companies. Most of the project ideas in this catalogue may form the basis for long and short master projects as well as regular 3rd...

3rd Semester and Master’s Thesis Ideas 2012

DEFF Research Database (Denmark)

Clausen, Johan

The report contain a list of project ideas proposed by the scientific staff at the Department of Civil Engineering, Aalborg University, and a number of companies. Most of the project ideas in this catalogue may form the basis for long and short candidate projects as well as regular 3rd semester...

Innovative States: Emerging Family Support and Education Programs. Arkansas, Iowa, Oregon, Vermont, Washington. Second Edition.

Science.gov (United States)

Harvard Family Research Project, Cambridge, MA.

The five states featured in this second edition of "Innovative States" were chosen because they reflect crucial elements in an emerging understanding of state policy making in family support and education. Creative state partnerships involving program development and funding are a key ingredient to successful endeavors. States rely on…

Buildings R&D Breakthroughs: Technologies and Products Supported by the Building Technologies Program

Energy Technology Data Exchange (ETDEWEB)

Weakley, Steven A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

2012-04-01

The purpose of the project described in this report is to identify and characterize commercially available products and emerging (near-commercial) technologies that benefited from the support of the Building Technologies Program (BTP) within the U.S. Department of Energy’s Office of Energy Efficiency and Renewable Energy. The investigation specifically focused on technology-oriented research and development (R&D) projects funded by BTP’s Emerging Technologies subprogram from 2005-2011.

WHO Polio Eradication Program: Problems and Solutions

Directory of Open Access Journals (Sweden)

S. M. Kharit

2016-01-01

Full Text Available In 2013 WHO re-evaluated its main goals of the polio eradication program. A modernization program was accepted with regard to the National vaccination calendars worldwide which includes a step-by-step refusal from the living polio vaccine (OPV and a total transition to the inactivated polio vaccine (IPV starting in 2019. Because of the total eradication of the polio type 2 virus, as an intermediate step the 3-valence OPV was substituted with the 2-valence OPV, which does not contain the type 2 polio virus, in April 2016. The aim of the article is to present the history of polio prevention and to state the reasons for the adoption of 3rd edition of the Global Polio Eradication Initiative. The new approaches were defined for eradication of wild polio virus type 1 and vaccine related strains. A new strategy for global switch to inactivated polio vaccine by 2019 was suggested.

The Effects of State R&D Tax Credits in Stimulating Private R&D Expenditure: A Cross-State Empirical Analysis

Science.gov (United States)

Wu, Yonghong

2005-01-01

This is a cross-state empirical study which examines the effects of state research and development (R&D) tax credits on private R&D expenditure in the states. Other explanatory variables include federal R&D subsidies, public services in higher education and R&D-targeted programs as well as other control variables. The statistical result shows that…

A Goal Programming R&D (Research and Development) Project Funding Model of the U.S. Army Strategic Defense Command Using the Analytic Hierarchy Process.

Science.gov (United States)

1987-09-01

A187 899 A GOAL PROGRANNIN R&D (RESEARCH AND DEVELOPMENT) 1/2 PROJECT FUNDING MODEL 0 (U) NAVAL POSTGRADUATE SCHOOL MONTEREY CA S M ANDERSON SEP 87...PROGRAMMING R&D PROJECT FUNDING MODEL OF THE U.S. ARMY STRATEGIC DEFENSE COMMAND USING THE ANALYTIC HIERARCHY PROCESS by Steven M. Anderson September 1987...jACCESSION NO TITI E (Influde Securt ClauAIcatsrn) A Goal Programming R&D Project Funding Model of the U.S. Army Strategic Defense Command Using the

CANDU Safety R&D Status, Challenges, and Prospects in Canada

Directory of Open Access Journals (Sweden)

W. Shen

2015-01-01

Full Text Available In Canada, safe operation of CANDU (CANada Deuterium Uranium; it is a registered trademark of Atomic Energy of Canada Limited reactors is supported by a full-scope program of nuclear safety research and development (R&D in key technical areas. Key nuclear R&D programs, facilities, and expertise are maintained in order to address the unique features of the CANDU as well as generic technology areas common to CANDU and LWR (light water reactor. This paper presents an overview of the CANDU safety R&D which includes background, drivers, current status, challenges, and future directions. This overview of the Canadian nuclear safety R&D programs includes those currently conducted by the COG (CANDU Owners Group, AECL (Atomic Energy of Canada Limited, Candu Energy Inc., and the CNSC (Canadian Nuclear Safety Commission and by universities via UNENE (University Network of Excellence in Nuclear Engineering sponsorship. In particular, the nuclear safety R&D program related to the emerging CANDU ageing issues is discussed. The paper concludes by identifying directions for the future nuclear safety R&D.

[A revolution postponed indefinitely.WHO classification of tumors of the breast 2012: the main changes compared to the 3rd edition (2003)].

Science.gov (United States)

Nenutil, Rudolf

2015-01-01

In 2012, the new classification of the fourth series WHO blue books of breast tumors was released. The current version represents a fluent evolution, compared to the third edition. Some limited changes regarding terminology, definitions and the inclusion of some diagnostic units were adopted. The information about the molecular biology and genetic background of breast carcinoma has been enriched substantially.

CERES ERBE-like Monthly Regional Averages (ES-9) in HDF ( CER_ES9_Aqua-FM3_Edition1-CV)

Science.gov (United States)

Wielicki, Bruce A. (Principal Investigator)

The ERBE-like Monthly Regional Averages (ES-9) product contains a month of space and time averaged Clouds and the Earth's Radiant Energy System (CERES) data for a single scanner instrument. The ES-9 is also produced for combinations of scanner instruments. All instantaneous shortwave and longwave fluxes at the Top-of-the-Atmosphere (TOA) from the CERES ES-8 product for a month are sorted by 2.5-degree spatial regions, by day number, and by the local hour of observation. The mean of the instantaneous fluxes for a given region-day-hour bin is determined and recorded on the ES-9 along with other flux statistics and scene information. For each region, the daily average flux is estimated from an algorithm that uses the available hourly data, scene identification data, and diurnal models. This algorithm is 'like' the algorithm used for the Earth Radiation Budget Experiment (ERBE). The ES-9 also contains hourly average fluxes for the month and an overall monthly average for each region. These average fluxes are given for both clear-sky and total-sky scenes. The following CERES ES9 data sets are currently available: CER_ES9_FM1+FM2_Edition1 CER_ES9_PFM+FM1+FM2_Edition1 CER_ES9_PFM+FM1+FM2_Edition2 CER_ES9_PFM+FM1_Edition1 CER_ES9_PFM+FM2_Edition1 CER_ES9_PFM+FM1_Edition2 CER_ES9_PFM+FM2_Edition2 CER_ES9_TRMM-PFM_Edition1 CER_ES9_TRMM-PFM_Edition2 CER_ES9_Terra-FM1_Edition1 CER_ES9_Terra-FM2_Edition1 CER_ES9_FM1+FM2_Edition2 CER_ES9_Terra-FM1_Edition2 CER_ES9_Terra-FM2_Edition2 CER_ES9_Aqua-FM3_Edition1 CER_ES9_Aqua-FM4_Edition1 CER_ES9_FM1+FM2+FM3+FM4_Edition1 CER_ES9_Aqua-FM3_Edition2 CER_ES9_Aqua-FM4_Edition2 CER_ES9_FM1+FM3_Edition2 CER_ES9_FM1+FM4_Edition2 CER_ES9_Aqua-FM3_Edition1-CV CER_ES9_Aqua-FM4_Edition1-CV CER_ES9_Terra-FM1_Edition1-CV CER_ES9_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1998-01-01; Stop_Date=2006-10-31] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost

Biomass Energy Data Book: Edition 3

Energy Technology Data Exchange (ETDEWEB)

Boundy, Robert Gary [ORNL; Davis, Stacy Cagle [ORNL

2010-12-01

The Biomass Energy Data Book is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the Biomass Program in the Energy Efficiency and Renewable Energy (EERE) program of the Department of Energy (DOE). Designed for use as a convenient reference, the book represents an assembly and display of statistics and information that characterize the biomass industry, from the production of biomass feedstocks to their end use, including discussions on sustainability. This is the third edition of the Biomass Energy Data Book which is only available online in electronic format. There are five main sections to this book. The first section is an introduction which provides an overview of biomass resources and consumption. Following the introduction to biomass, is a section on biofuels which covers ethanol, biodiesel and bio-oil. The biopower section focuses on the use of biomass for electrical power generation and heating. The fourth section is on the developing area of biorefineries, and the fifth section covers feedstocks that are produced and used in the biomass industry. The sources used represent the latest available data. There are also four appendices which include frequently needed conversion factors, a table of selected biomass feedstock characteristics, and discussions on sustainability. A glossary of terms and a list of acronyms are also included for the reader's convenience.

Announced document collection of the 3rd information exchange meeting on radioactive waste disposal research network

International Nuclear Information System (INIS)

2008-03-01

The 3rd meeting on 'Radioactive Waste Disposal Research Network' was held at the Ricotti techno community square of JAEA on September 3 and 4, 2007. The 'Radioactive Waste Disposal Research Network' was established in Interorganization Atomic Energy Research Program under academic collaborative agreement between Japan Atomic Energy Agency and the University of Tokyo. The objective is to bring both research infrastructures and human expertise in Japan to an adequate performance level, thereby contributing to the development of the fundamental research area in the field of radioactive waste disposal. This lecture material is a collection of presentations and discussions during the information exchange meeting. (author)

3rd International Multidisciplinary Microscopy and Microanalysis Congress

CERN Document Server

Oral, Zehra

2017-01-01

The 3rd International Multidisciplinary Microscopy Congress (InterM2015), held from 19 to 23 October 2015, focused on the latest developments concerning applications of microscopy in the biological, physical and chemical sciences at all dimensional scales, advances in instrumentation, techniques in and educational materials on microscopy. These proceedings gather 17 peer-reviewed technical papers submitted by leading academic and research institutions from nine countries and representing some of the most cutting-edge research available.

Comparison of Assemblies of Four-Link Structural Groups of 3rd Class on the Transmission Angle

Directory of Open Access Journals (Sweden)

Matsyuk I.N.

2016-05-01

Full Text Available Comparison of various assemblies of four-link structural group of 3rd class with revolute joints on the transmission angle is performed. Equations of the trajectories of plug points of one of the groups of joint are obtained to determine transmission angles. Derived functions of these equations enable to determine the values of transmission angles for each assembly group. It is shown that only two assemblies of maximum possible assembling number of such group (six have practical value. The solution of this problem was performed with the help of Mathcad program.

RNA editing makes mistakes in plant mitochondria: editing loses sense in transcripts of a rps19 pseudogene and in creating stop codons in coxI and rps3 mRNAs of Oenothera.

Science.gov (United States)

Schuster, W; Brennicke, A

1991-01-01

An intact gene for the ribosomal protein S19 (rps19) is absent from Oenothera mitochondria. The conserved rps19 reading frame found in the mitochondrial genome is interrupted by a termination codon. This rps19 pseudogene is cotranscribed with the downstream rps3 gene and is edited on both sides of the translational stop. Editing, however, changes the amino acid sequence at positions that were well conserved before editing. Other strange editings create translational stops in open reading frames coding for functional proteins. In coxI and rps3 mRNAs CGA codons are edited to UGA stop codons only five and three codons, respectively, downstream to the initiation codon. These aberrant editings in essential open reading frames and in the rps19 pseudogene appear to have been shifted to these positions from other editing sites. These observations suggest a requirement for a continuous evolutionary constraint on the editing specificities in plant mitochondria. Images PMID:1762921

Vibration Theory, Vol. 3

DEFF Research Database (Denmark)

Nielsen, Søren R. K.

The present textbook has been written based on previous lecture notes for a course on stochastic vibration theory that is being given on the 9th semester at Aalborg University for M. Sc. students in structural engineering. The present 4th edition of this textbook on linear stochastic vibration th...... theory is unchanged in comparison to the 3rd edition. Only a few errors have been corrected.......The present textbook has been written based on previous lecture notes for a course on stochastic vibration theory that is being given on the 9th semester at Aalborg University for M. Sc. students in structural engineering. The present 4th edition of this textbook on linear stochastic vibration...

Heat Increases the Editing Efficiency of Human Papillomavirus E2 Gene by Inducing Upregulation of APOBEC3A and 3G.

Science.gov (United States)

Yang, Yang; Wang, Hexiao; Zhang, Xinrui; Huo, Wei; Qi, Ruiqun; Gao, Yali; Zhang, Gaofeng; Song, Bing; Chen, Hongduo; Gao, Xinghua

2017-04-01

Apolipoprotein B mRNA-editing catalytic polypeptide (APOBEC) 3 proteins have been identified as potent viral DNA mutators and have broad antiviral activity. In this study, we demonstrated that apolipoprotein B mRNA-editing catalytic polypeptide 3A (A3A) and A3G expression levels were significantly upregulated in human papillomavirus (HPV)-infected cell lines and tissues. Heat treatment resulted in elevated expression of A3A and A3G in a temperature-dependent manner in HPV-infected cells. Correspondingly, HPV-infected cells heat-treated at 44 °C showed accumulated G-to-A or C-to-T mutation in HPV E2 gene. Knockdown of A3A or A3G could promote cell viability, along with the lower frequency of A/T in HPV E2 gene. In addition, regressing genital viral warts also harbored high G-to-A or C-to-T mutation in HPV E2 gene. Taken together, we demonstrate that apolipoprotein B mRNA-editing catalytic polypeptide 3 expression and editing function was heat sensitive to a certain degree, partly explaining the mechanism of action of local hyperthermia to treat viral warts. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

3rd International Conference on Multimedia Technology

CERN Document Server

Yang, Jian; Jiao, Feng

2014-01-01

Proceedings of the 3rd International Conference on Multimedia Technology (ICMT2013) focuses on both the theory and applications of multimedia technology. The recent advances, new research findings and applications in the fields of theoretical, experimental and applied image & video processing and multimedia technology presented at the conference are brought together in this book. It will serve as a valuable reference for scientists and engineers working in multimedia and related fields. Prof. Aly A. Farag works at the University of Louisville, USA; Prof. Jian Yang works at Tsinghua University, China; Dr. Feng Jiao works at Nanjing University of Information Science & Technology, China.

Operational Transformation In Co-Operative Editing

Directory of Open Access Journals (Sweden)

Mandeep Kaur

2015-08-01

Full Text Available Cooperative Editing Systems in real-time allows a virtual team to view and edit a shared document at the same time. The document shared must be synchronized in order to ensure consistency for all the participants. This paper describes the Operational Transformation the evolution of its techniques its various applications major issues and achievements. In addition this paper will present working of a platform where two users can edit a code programming file at the same time.

Evaluation of paracavernous cranial nerves (3rd to 6th) with CT

International Nuclear Information System (INIS)

Tsuha, Mitsuru; Okamura, Tomomi; Abiko, Seisho; Aoki, Hideo

1984-01-01

We have now used CT to evaluate the cavernous sinuses, especially the 3rd, 4th, 5th, and 6th cranial nerves. adjacent to them. Twenty cases, presumably all having sellar or parasellar lesions, were examined by means of thin-slice (2-4 mm) axial and coronal (including both direct and reconstructed methods) CT studies. Moreover, three blocks of the sellar region obtained from adult cadavers were examined beforehand by CT scan, and the courses of the respective paracavernous cranial nerves were confirmed by microsurgical dissection. As a result, the following conclusions were obtained. 1. It was valuable to perform a post-enhanced direct coronal study for the definite identification of the paracavernous cranial nerves (3rd to 6th cranial nerves). 2. Also valuable was a magnified CT film of the parasellar regions, which made the identification of the parasellar cranial nerves clearer. 3. In the clinical cases showing a normal shape of the cavernous sinuses on CT, each cranial nerve was evaluated. In the axial studies (almost 10 to 15 degrees anterior to Reid's basal line), the frequencies of the identification of the 3rd, 5th, and 6th cranial nerves were 76%, 97% (as to the Gasserian ganglion), and 21% respectively. None of the 4th cranial nerve was visualized in the cases examined. On the other hand, the frequencies of the identification of the 3rd, 5th, and 6th cranial nerves were 83%, 86%, and 21% respectively in the direct coronal studies and 62%, 57%, and 4% in those of the reconstructed films. The visualization of each cranial nerve in the direct coronal study was better than when the reconstructed method was used. Finally, a schematic presentation of the cranial nerves adjacent to the cavernous sinuses was made in the axial and coronal projections. (J.P.N.)

3rd International Conference on X-ray Technique

Science.gov (United States)

Potrakhov, N. N.; Gryaznov, A. Yu; Lisenkov, A. A.; Kostrin, D. K.

2017-02-01

In this preface a brief history, modern aspects and future tendencies in development of the X-ray technique as seen from the 3rd International Conference on X-ray Technique that was held on 24-25 November 2016 in Saint Petersburg, Russia are described On 24-25 November 2016 in Saint Petersburg on the basis of Saint Petersburg State Electrotechnical University “LETI” n. a. V. I. Ulyanov (Lenin) was held the 3rd International Conference on X-ray Technique. The tradition to hold a similar conference in our country was laid in Soviet times. The last of them, the All-Union Conference on the Prospects of X-ray Tubes and Equipment was organized and held more than a quarter century ago - on 21-23 November 1999, at the initiative and under the leadership of the chief engineer of the Leningrad association of electronic industry “Svetlana” Borovsky Alexander Ivanovich and the chief of special design bureau of X-ray devices of “Svetlana” Shchukin Gennady Anatolievich. The most active part in the organization and work of the conference played members of the department of X-ray and electron beam instruments of Leningrad Electrotechnical Institute “LETI” (the former name of Saint Petersburg State Electrotechnical University “LETI”), represented by head of the department professor Ivanov Stanislav Alekseevich.

The 3rd ATLAS Domestic Standard Problem for Improvement of Safety Analysis Technology

International Nuclear Information System (INIS)

Choi, Ki-Yong; Kang, Kyoung-Ho; Park, Yusun; Kim, Jongrok; Bae, Byoung-Uhn; Choi, Nam-Hyun

2014-01-01

The third ATLAS DSP (domestic standard problem exercise) was launched at the end of 2012 in response to the strong need for continuation of the ATLAS DSP. A guillotine break of a main steam line without LOOP at a zero power condition was selected as a target scenario, and it was successfully completed in the beginning of 2014. In the 3 rd ATLAS DSP, comprehensive utilization of the integral effect test data was made by dividing analysis with three topics; 1. scale-up where extrapolation of ATLAS IET data was investigated 2. 3D analysis where how much improvement can be obtained by 3D modeling was studied 3. 1D sensitivity analysis where the key phenomena affecting the SLB simulation were identified and the best modeling guideline was achieved. Through such DSP exercises, it has been possible to effectively utilize high-quality ATLAS experimental data of to enhance thermal-hydraulic understanding and to validate the safety analysis codes. A strong human network and technical expertise sharing among the various nuclear experts are also important outcomes from this program

Vom work Book Journal, 2011 3rd Edition

African Journals Online (AJOL)

USER

sudden change in diet, a doe's immune system is compromised which consequentially suppressed, if not completely negates ... Department of Veterinary Medicine, Depatment of Veterinary Surgery and Radiology, Department of Theriogenology and Animal. 4. 5. Production, Department of Veterinary Physiology and ...

Vom work Book Journal, 2011 3rd Edition

African Journals Online (AJOL)

USER

Iwamato et al.,. 1984; Timson and Dudenhoeffer 1985; Hebert et al., 1988; Kandarian and White, 1989; Roy et al.,. 1991). This may likely be responsible for the growth observed in the individual muscle, especially the gluteobiceps in the hind limb and.

Vom work Book Journal, 2011 3rd Edition

African Journals Online (AJOL)

USER

fascia of the Sartorius muscle. The skin flaps were brought in apposition and the edges were sutured with interrupted suture using Nylon. The suture on the skin was removed twelve days post surgery. POST OPERATIVE CARE. The bitch was injected Penicillin at the dose of. 10,000IU/Kg IM and Streptomycin at the dose.

Vom work Book Journal, 2011 3rd Edition

African Journals Online (AJOL)

USER

In: HARARI, J.: Surgical. Complication of Wound Healing in the Small Animal. Practice. W. B. Saunders Company 143-146. MULLER, G. H., KIRK, R. W. and SCOTT, D. W. (1998): th. Small animal dermatology, 4 Ed. W. B. Saunders. Company, Philadelphia. 771-775. PASCOE, R. R. (1981): Equine dermatoses. Syndey,.

Data of evolutionary structure change: 1ONAD-2D3RD [Confc[Archive

Lifescience Database Archive (English)

Full Text Available 1ONAD-2D3RD 1ONA 2D3R D D ADTIVAVELDTYPNTDIGDPSYPHIGIDIKSVRSKKTAK...WNMQNGKVGTAHIIYNSVDKRLSAVVSYPNADSATVSYDVDLDNVLPEWVRVGLSASTGLYKETNTILSWSFTSKLK------TNALHFMFNQFSKDQKDLILQGDAT...n> 1ONA D 1ONAD TRVS

The Role of Training and Promotion to Increase The 3rd Party Funds Indonesian Islamic Banking

Directory of Open Access Journals (Sweden)

Rahmat Hidayat

2014-03-01

Full Text Available Objective – This study aims to determine whether the role of training is much larger than the promotion in raising third-party funds in Islamic banks in Indonesia given the cost of the training is spent is greater than the cost of promotion. This study empirically examines the relationship and impact of training and promotion to raise funds for a 3rd party in Indonesia Islamic banks.Methods – This study uses secondary data Islamic commercial banks in the form of panel (time-series and cross-section of Bank Indonesia data from 2010 until 2012. There are two independent variables training cost (X1 and promotion cost (X2 and one dependent variable is 3rd-party funds (Y. The analysis technique used path analysis to examine the role of training and the promotion of financial performance (The 3rd Party Funds.Result – Simultaneously, training and promotion gives an effect by 52%, and partially or individual training gives an insignificant negative effect, while the promotion has a significant positive impact on financial performance (financial-party funds on Islamic banking.Conclusion – The role of promotion is higher in raising The 3rd Party Funds than training. Keywords : Cost, Training, Promotion, The 3rd Party Funds 

Epidemiology of 3rd generation cephalosporin-resistant Escherichia coli on dairy farms

Science.gov (United States)

Dairy cattle have been identified as a reservoir for 3rd generation cephalosporin (3GC)-resistant Escherichia coli. We previously identified 3GC-resistant E. coli from manure composite samples of calves and cows in a survey of 80 farms in Pennsylvania. Resistant strains were most frequently isolated...

Tretji slovenski MoodleMoot = 3rd Slovenian MoodleMoot

Directory of Open Access Journals (Sweden)

Viktorija Sulčič

2009-09-01

Full Text Available This year, the 3rd international moodle.si conference took place in Koper and brought together Slovenian users of Moodle, an open-source learning management system. This year’s conference, which is presented in the paper, was especially interesting due to its plenary session being wholly dedicated to the national e-schooling project. An interesting addition was also Apple’s workshop about using iLife applications in education.

Journal of Special Operations Medicine, Volume 2, Edition 3

Science.gov (United States)

2002-01-01

muscle necrosis is extensive it produces a tissue lysis syndrome with lactic acidosis, hyperkalemia, hyperuricemia, hyperphosphatemia, hypocalcemia ... adults , and may require adjust- ment for elderly or very young patients. Volume 2, Edition 3 / Summer 02 27 6. Costrini A: Emergency treatment of...completed annual refresher training in direct laryngoscopy three days prior to this study. A LaedralTM adult intubating manikin was used as the patient in

Journal of Special Operations Medicine, Volume 6, Edition 3

Science.gov (United States)

2006-01-01

between the lower leg muscular planes. These are often times located in multiple places and not radiographically detectable. Volume 6, Edition 3...tinged. Physical examination was remarkable for rales and rhonchi at the left base. There was no jugular venous distension or tracheal deviation... muscular or subcutaneous epinephrine are the first-line treatments for these rare but serious conditions; respi- ratory and intravascular fluid may

The role of hemorrhoidopexy in the management of 3rd degree hemorrhoids.

Science.gov (United States)

Pramateftakis, M G

2010-11-01

Hemorrhoidopathy is a very common benign surgical pathology. Hemorrhoids are divided into 4 stages, depending on symptoms and degree of prolapse. Hemorrhoidopexy is a technique developed for the treatment of 3rd degree hemorrhoids, but its application has been extended to the treatment of 4th degree hemorrhoids as well. Nevertheless, recent studies identify weaknesses of the PPH in the treatment of 4th degree hemorrhoids. One hundred and twenty-six consecutive patients with 3rd degree hemorrhoids underwent stapled hemorrhoidopexy. All procedures were performed under general anesthesia with the patient in lithotomy position. A phosphate enema was given to the patient 2 h before the procedure, and cephalosporine and metronidazole were administered at anesthesia induction. Most patients were discharged the day after the operation. All patients were reassessed at 1, 6 weeks, 6 and 12 months after the procedure. The mean operating time was 16.3 min. Of all patients, 5.8% complained of mild rectal pain for a post-operative period of 5-12 days, 5.8% developed post-operative urinary retention, managed with catheterization, 13.3% experienced fecal urgency while 5.8% experienced gas incontinence, which subsided 2-8 weeks from surgery. The mean hospital stay was 1.2 days. Most patients returned to daily activities within 2-5 days. Ninety-five percent of patients returned for their follow-up visits. Recurrence of the disease occurred in 8 patients (6.6%). It was managed conservatively in 2 patients, 3 underwent redo hemorrhoidopexy and 3 underwent classic hemorrhoidectomy. According to our results, stapled hemorrhoidopexy seems to be a safe, pain-free and, in the long-term, effective technique for the treatment of 3rd degree hemorrhoids.

Transportation Energy Data Book: Edition 28

Energy Technology Data Exchange (ETDEWEB)

Davis, Stacy Cagle [ORNL; Diegel, Susan W [ORNL; Boundy, Robert Gary [ORNL

2009-06-01

The Transportation Energy Data Book: Edition 28 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with U.S Department of Energy, Office of Energy Efficiency and Renewable Energy, Vehicle Technologies Program and the Hydrogen, Fuel Cells, and Infrastructure Technologies Program. Designed for use as a desk-top reference, the data book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest edition of the Data Book are available to a larger audience via the Internet (cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2 energy; Chapter 3 highway vehicles; Chapter 4 light vehicles; Chapter 5 heavy vehicles; Chapter 6 alternative fuel vehicles; Chapter 7 fleet vehicles; Chapter 8 household vehicles; and Chapter 9 nonhighway modes; Chapter 10 transportation and the economy; Chapter 11 greenhouse gas emissions; and Chapter 12 criteria pollutant emissions. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the readers convenience.

Atmel AVR Microcontroller Primer Programming and Interfacing, Second Edition

CERN Document Server

Barrett, Steven F

2012-01-01

This textbook provides practicing scientists and engineers a primer on the Atmel AVR microcontroller. In this second edition we highlight the popular ATmega164 microcontroller and other pin-for-pin controllers in the family with a complement of flash memory up to 128 kbytes. The second edition also adds a chapter on embedded system design fundamentals and provides extended examples on two different autonomous robots. Our approach is to provide the fundamental skills to quickly get up and operating with this internationally popular microcontroller. We cover the main subsystems aboard the ATmega

Retrospective Benefit-Cost Evaluation of U.S. DOE Wind Energy R&D Program: Impact of Selected Energy Technology Investments

Energy Technology Data Exchange (ETDEWEB)

Pelsoci, Thomas M. [Delta Research Co., Evanston, IL (United States)

2010-06-01

This benefit-cost analysis focuses on the DOE Wind Energy Program's public sector R&D investments and returns. The analysis accounts for the program's additionality – that is, comparing what has happened as a result of the program to what would have happened without it. The analysis does not address the return on the investments of private companies ("private returns"). Public returns on the program's investments from 1976 to 2008 are identified and analyzed using retrospective analysis.

Compendium of fruit fly host information (CoFFHI), edition 3.0

Science.gov (United States)

The Compendium of Fruit Fly Host Information (CoFFHI), edition 3.0 (available at: https://coffhi.cphst.org/), developed through collaborative efforts of scientists in USDA-APHIS, USDA-ARS, and the Center for Integrated Pest Management (CIPM) of North Carolina State University (NCSU), provides centra...

Comparing individuals with learning disability and those with borderline IQ: a confirmatory factor analysis of the Wechsler Adult Intelligence Scale (3rd edition).

OpenAIRE

MacLean, Hannah Ng On-Nar

2011-01-01

Background: Support for the four factor construct validity of the third edition of the Wechsler Adult Intelligence Scale (WAIS-III) has been found in clinical and non clinical populations but some studies question whether more complex models consistent with the concepts of fluid and crystallised intelligence provide a better explanation of the data. The WAIS-III is frequently used in the diagnosis of learning disability, however, previous exploratory factor analysis of data from a population ...

23rd Recent Advances in Retailing & Services Science Conference, July 11-14, 2016, Edinburgh, Scotland : book of abstracts

NARCIS (Netherlands)

Rasouli, S.; Timmermans, H.J.P.

2016-01-01

This book includes the (edited) abstracts of the papers that will be presented at the 23rd Recent Advances in Retailing and Services Science Conference, at the Carlton/Hilton hotel, Edinburgh, Scotland, July 11- 16, 2016. The aim of the conference is to bring together an international and

3rd Session of the Sant Cugat Forum on Astrophysics

CERN Document Server

Gravitational wave astrophysics

2015-01-01

This book offers review chapters written by invited speakers of the 3rd Session of the Sant Cugat Forum on Astrophysics — Gravitational Waves Astrophysics. All chapters have been peer reviewed. The book goes beyond normal conference proceedings in that it provides a wide panorama of the astrophysics of gravitational waves and serves as a reference work for researchers in the field.

The 3rd Sino-Japan nuclear medicine conference

International Nuclear Information System (INIS)

1999-01-01

The 3rd Sino-Japan Nuclear Medicine Conference was hold on May 11-13, 1999 in Xi'an of China by Chinese Society of Nuclear Medicine, Japanese Society of Nuclear Medicine, Chinese Medicine Association and Japan-China Medicine Association. 62 articles were published in the proceeding of the conference. The contents of the articles include development and application of the radioisotopes (such as Tc-99, I-125, I-131, F-18, In-111, Tl-201, Ga-67, Sm-153, Re-188) and its radiopharmaceuticals, but application also include radiotherapy and diagnosis in the oncology and pathology by SPECT and PET

Advanced lectures on multiprocessor programming (1/3)

CERN Multimedia

CERN. Geneva

2011-01-01

Three classes (60 mins) on Multiprocessor Programming Prof. Dr. Christoph von Praun Georg-Simon-Ohm University of Applied Sciences Nuremberg, Germany This is an advanced class on multiprocessor programming. The class gives an introduction to principles of concurrent objects and the notion of different progress guarantees that concurrent computations can have. The focus of this class is on non-blocking computations, i.e. concurrent programs that do not make use of locks. We discuss the implementation of practical non-blocking data structures in detail. 1st class: Introduction to concurrent objects 2nd class: Principles of non-blocking synchronization 3rd class: Concurrent queues Brief Bio of Christoph von Praun Christoph worked on a variety of analysis techniques and runtime platforms for parallel programs. Hist most recent research studies programming models and tools that support transactional synchronization. In prior work, which he also did at the IBM T.J. Watson Research Center in Yorktown Height...

High field accelerator magnet R&D in Europe

NARCIS (Netherlands)

Devred, A.; Baynham, D.E.; Bottura, L.; Chorowski, M; Fabbricatore, P.; Leroy, D.; den Ouden, A.; Rifflet, J.M.; Rossi, L.; Vincent-Viry, O.; Volpini, G.

2004-01-01

The LHC magnet R&D Program has shown that the limit of NbTi technology at 1.8 K was in the range 10 to 10.5 T. Hence, to go beyond the 10-T threshold, it is necessary to change of superconducting material. Given the state of the art in HTS, the only serious candidate is Nb/sub 3/Sn. A series of

Clarithromycin (Biaxin)-lenalidomide-low-dose dexamethasone (BiRd) versus lenalidomide-low-dose dexamethasone (Rd) for newly diagnosed myeloma.

Science.gov (United States)

Gay, Francesca; Rajkumar, S Vincent; Coleman, Morton; Kumar, Shaji; Mark, Tomer; Dispenzieri, Angela; Pearse, Roger; Gertz, Morie A; Leonard, John; Lacy, Martha Q; Chen-Kiang, Selina; Roy, Vivek; Jayabalan, David S; Lust, John A; Witzig, Thomas E; Fonseca, Rafael; Kyle, Robert A; Greipp, Philip R; Stewart, A Keith; Niesvizky, Ruben

2010-09-01

The objective of this case-matched study was to compare the efficacy and toxicity of the addition of clarithromycin (Biaxin) to lenalidomide/low-dose dexamethasone (BiRd) vs. lenalidomide/low-dose dexamethasone (Rd) for newly diagnosed myeloma. Data from 72 patients treated at the New York Presbyterian Hospital-Cornell Medical Center were retrospectively compared with an equal number of matched pair mates selected among patients seen at the Mayo Clinic who received Rd. Case matching was blinded and was performed according to age, gender, and transplant status. On intention-to-treat analysis, complete response (45.8% vs. 13.9%, P < 0.001) and very-good-partial-response or better (73.6% vs. 33.3%, P < 0.001) were significantly higher with BiRd. Time-to-progression (median 48.3 vs. 27.5 months, P = 0.071), and progression-free survival (median 48.3 vs. 27.5 months, P = 0.044) were higher with BiRd. There was a trend toward better OS with BiRd (3-year OS: 89.7% vs. 73.0%, P = 0.170). Main grade 3-4 toxicities of BiRd were hematological, in particular thrombocytopenia (23.6% vs. 8.3%, P = 0.012). Infections (16.7% vs. 9.7%, P = 0.218) and dermatological toxicity (12.5% vs. 4.2%, P = 0.129) were higher with Rd. Results of this case-matched analysis suggest that there is significant additive value when clarithromycin is added to Rd. Randomized phase III trials are needed to confirm these results. © 2010 Wiley-Liss, Inc.

Data-Dictionary-Editing Program

Science.gov (United States)

Cumming, A. P.

1989-01-01

Access to data-dictionary relations and attributes made more convenient. Data Dictionary Editor (DDE) application program provides more convenient read/write access to data-dictionary table ("descriptions table") via data screen using SMARTQUERY function keys. Provides three main advantages: (1) User works with table names and field names rather than with table numbers and field numbers, (2) Provides online access to definitions of data-dictionary keys, and (3) Provides displayed summary list that shows, for each datum, which data-dictionary entries currently exist for any specific relation or attribute. Computer program developed to give developers of data bases more convenient access to the OMNIBASE VAX/IDM data-dictionary relations and attributes.

3rd Joint Dutch-Brazil School on Theoretical Physics

CERN Document Server

2015-01-01

The Joint Dutch-Brazil School on Theoretical Physics is now in its third edition with previous schools in 2007 and 2011. This edition of the school will feature minicourses by Nima Arkani-Hamed (IAS Princeton), Jan de Boer (University of Amsterdam) and Cumrun Vafa (Harvard University), as well as student presentations. The school is jointly organized with the Dutch Research School of Theoretical Physics (DRSTP) and is intended for graduate students and researchers in the field of high-energy theoretical physics. There is no registration fee and limited funds are available for local and travel support of participants. This school in São Paulo will be preceded by the XVIII J. A. Swieca School in Campos de Jordão.

49 CFR 195.3 - Incorporation by reference.

Science.gov (United States)

2010-10-01

...); 195.440(c). (15) API Recommended Practice 1165, “Recommended Practice for Pipeline SCADA Displays.... (PRCI): (1) AGA Pipeline Research Committee, Project PR-3-805, “A Modified Criterion for Evaluating the... Specification 6D, “Specification for Pipeline Valves” (23rd edition, April 2008, effective October 1, 2008) and...

The 3rd Asia–Pacific Transport Working Group (APTWG) Meeting

International Nuclear Information System (INIS)

Jhang, Hogun; Diamond, P.H.; Leconte, M.; Kwon, J.M.; Ida, K.; Tamura, N.; Kosuga, Y.

2014-01-01

This conference report summarizes the contributions to and discussions at the 3rd Asia–Pacific Transport Working Group (APTWG) meeting held in Jeju-island, Korea, on 21–24 May 2013. The main objective of the meeting is to develop a predictive understanding of transport mechanisms in magnetically confined fusion plasmas. In an effort to accomplish this objective, four technical working groups were organized under the headings: (1) transport barrier formation and confinement enhancement, (2) 3D effects and Magnetohydrodynamic–turbulence interaction, (3) momentum transport and non-locality and (4) particle/impurity transport and energetic particles. (conference report)

1.3 GHz superconducting RF cavity program at Fermilab

Energy Technology Data Exchange (ETDEWEB)

Ginsburg, C.M.; Arkan, T.; Barbanotti, S.; Carter, H.; Champion, M.; Cooley, L.; Cooper, C.; Foley, M.; Ge, M.; Grimm, C.; Harms, E.; /Fermilab

2011-03-01

At Fermilab, 9-cell 1.3 GHz superconducting RF (SRF) cavities are prepared, qualified, and assembled into cryomodules (CMs) for Project X, an International Linear Collider (ILC), or other future projects. The 1.3 GHz SRF cavity program includes targeted R&D on 1-cell 1.3 GHz cavities for cavity performance improvement. Production cavity qualification includes cavity inspection, surface processing, clean assembly, and one or more cryogenic low-power CW qualification tests which typically include performance diagnostics. Qualified cavities are welded into helium vessels and are cryogenically tested with pulsed high-power. Well performing cavities are assembled into cryomodules for pulsed high-power testing in a cryomodule test facility, and possible installation into a beamline. The overall goals of the 1.3 GHz SRF cavity program, supporting facilities, and accomplishments are described.

Introduction to Recreation Services for People with Disabilities: A Person-Centered Approach. 3rd Edition

Science.gov (United States)

Bullock, Charles C.; Mahon, Michael J.; Killingsworth, Charles L.

2010-01-01

Ultimately, all successful recreation programs center around its participants wants and needs. Serving people with disabilities is no exception. "Introduction to Recreation Services for People with Disabilities" is intended to be an introductory book for anyone planning or working in the parks, recreation, and leisure service industry. Through…

Integrity of the core mitochondrial RNA-binding complex 1/nis vital for trypanosome RNA editing

Czech Academy of Sciences Publication Activity Database

Huang, Zhenqiu; Faktorová, Drahomíra; Křížová, A.; Kafková, L.; Read, L. K.; Lukeš, Julius; Hashimi, Hassan

2015-01-01

Roč. 21, č. 12 (2015), s. 2088-2102 ISSN 1355-8382 R&D Projects: GA ČR GA15-21974S EU Projects: European Commission(XE) 289007 Institutional support: RVO:60077344 Keywords : RNA editing * mitochondrion * trypanosome Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 4.344, year: 2015

NIOSH Manual of Analytical Methods (third edition). Fourth supplement

Energy Technology Data Exchange (ETDEWEB)

1990-08-15

The NIOSH Manual of Analytical Methods, 3rd edition, was updated for the following chemicals: allyl-glycidyl-ether, 2-aminopyridine, aspartame, bromine, chlorine, n-butylamine, n-butyl-glycidyl-ether, carbon-dioxide, carbon-monoxide, chlorinated-camphene, chloroacetaldehyde, p-chlorophenol, crotonaldehyde, 1,1-dimethylhydrazine, dinitro-o-cresol, ethyl-acetate, ethyl-formate, ethylenimine, sodium-fluoride, hydrogen-fluoride, cryolite, sodium-hexafluoroaluminate, formic-acid, hexachlorobutadiene, hydrogen-cyanide, hydrogen-sulfide, isopropyl-acetate, isopropyl-ether, isopropyl-glycidyl-ether, lead, lead-oxide, maleic-anhydride, methyl-acetate, methyl-acrylate, methyl-tert-butyl ether, methyl-cellosolve-acetate, methylcyclohexanol, 4,4'-methylenedianiline, monomethylaniline, monomethylhydrazine, nitric-oxide, p-nitroaniline, phenyl-ether, phenyl-ether-biphenyl mixture, phenyl-glycidyl-ether, phenylhydrazine, phosphine, ronnel, sulfuryl-fluoride, talc, tributyl-phosphate, 1,1,2-trichloro-1,2,2-trifluoroethane, trimellitic-anhydride, triorthocresyl-phosphate, triphenyl-phosphate, and vinyl-acetate.

China’s R&D for Energy Efficient Buildings: Insights for U.S. Cooperation with China

Energy Technology Data Exchange (ETDEWEB)

Yu, Sha; Evans, Meredydd

2010-04-01

This report includes an evaluation of China’s current activities and future direction in building energy efficiency R&D and its relevance to DOE’s R&D activities under the Building Technologies Program in the Office of Energy Efficiency and Renewable Energy. The researchers reviewed the major R&D programs in China including the so-called 973 Program, the 863 Program, and the Key Technology R&D Program1 as well as the research activities of major research institutes. The report also reviewed several relevant documents of the Chinese government, websites (including the International Energy Agency and national and local governments in China), newsletters, and financial information listed in the program documents and websites.

Consumer psychology of tourism, hospitality and leisure, volume 3

NARCIS (Netherlands)

Crouch, G.I.; Perdue, R.R.; Timmermans, H.J.P.; Uysal, M.

2004-01-01

Knowledge of consumer psychology and consumer behaviour in relation to tourism is valuable in determining the success of tourism and hospitality ventures. The book is an edited collection of papers from the 3rd Symposium on Consumer Psychology of Tourism, Hospitality and Leisure, held in Melbourne,

Results of a Technical Review of the U.S. Climate Change Technology Program's R&D Portfolio

Energy Technology Data Exchange (ETDEWEB)

Brown, Marilyn A [ORNL

2006-07-01

The U.S. Climate Change Technology Program (CCTP) is a multi-agency planning and coordinating entity, led by the U.S. Department of Energy that aims to accelerate the development and facilitate the adoption of technologies to address climate change. In late 2005, CCTP asked Oak Ridge National Laboratory and Energetics Incorporated to organize and coordinate a review of the CCTP R&D portfolio using structured workshops. Each workshop focused on one of CCTP's six strategic goals: 1.Reduce emissions from energy end-use and infrastructure 2.Reduce emissions from energy supply 3.Capture and sequester carbon dioxide 4.Reduce emissions of non-CO2 greenhouse gases (GHG) 5.Improve capabilities to measure and monitor GHG emissions 6.Bolster basic science contributions to technology development To promote meaningful dialogue while ensuring broad coverage, a group of broadly experienced professionals with expertise in fields relevant to each CCTP goal were asked to participate in the portfolio reviews and associated workshops. A total of 75 experts participated in the workshops; 60 of these participants represented non-Federal organizations. This report summarizes the findings of the workshops and the results of the Delphi assessment of the CCTP R&D portfolio.

Recent Korean R&D in Satellite Communications

Science.gov (United States)

Lee, Ho-Jin; Kim, Jae Moung; Lee, Byung-Seub; Lee, Han; Ryoo, Jang-Soo

The R&D in satellite communications in Korea has been driven mainly by KCC (Korea Communications Commission) but in a small scale compared to Korea space development program organized by MEST (Ministry of Education, Science and Technology). Public and civilian satcom sector R&D has been led mainly by ETRI with small/medium companies contrary to rare investment in private sector while military sector R&D has been orchestrated by ADD with defense industry. By the COMS (Communication, Ocean and Meteorological Satellite) experimental Ka-band payload, Korea pursues a space qualification of own technology for national infrastructure evolution as well as industrialization of space R&D results. Once COMS launched and space qualified in 2009, subsequent application experiments and new technology R&D like UHDTV will entail service and industry promotion. The payload technology is expected for the next Korean commercial satellites or for new OBP satellites. The COMS ground control system and GNSS ground station technologies are under development for COMS operation and enhanced GNSS services along with advent of Galileo respectively. Satellite broadband mobile VSAT based on DVB-S2/RCS (+M) and low profile tracking antennas have been developed for trains, ships, and planes. While APSI is developing GMR-1 based Thuraya handset functions, ETRI is designing IMT-Advanced satellite radio interface for satellite and terrestrial dual-mode handheld communication system like Japanese STICS, with universities' satellite OFDM researches. A 21GHz Ka-band higher-availability scalable HD broadcasting technology and SkyLife's hybrid satellite IPTV technology are being developed. In near term Korea will extend R&D programs to upgrade the space communication infrastructure for universal access to digital opportunity and safer daily life from disaster, and to promote space green IT industrialization, national security, and space resources sovereign. Japanese stakeholders are invited to establish

FY2014 Energy Storage R&D Annual Progress Report

Energy Technology Data Exchange (ETDEWEB)

none,

2015-03-01

The Energy Storage research and development (R&D) subprogram within the DOE Vehicle Technologies Office (VTO) provides support and guidance for projects focusing on batteries for plug-in electric vehicles. Program targets focus on overcoming technical barriers to enable market success including: (1) significantly reducing battery cost, (2) increasing battery performance (power, energy, durability), (3) reducing battery weight & volume, and (4) increasing battery tolerance to abusive conditions such as short circuit, overcharge, and crush. This report describes the progress made on the research and development projects funded by the Energy Storage subprogram in 2014. You can download individual sections at the following website, http://energy.gov/eere/vehicles/downloads/vehicle-technologies-office-2014-energy-storage-rd-annual-report.

The Need for an R&D and Upgrade Program for CMS Software and Computing

CERN Document Server

Elmer, Peter; Stenson, Kevin; Wittich, Peter

2013-01-01

Over the next ten years, the physics reach of the Large Hadron Collider (LHC) at the European Organization for Nuclear Research (CERN) will be greatly extended through increases in the instantaneous luminosity of the accelerator and large increases in the amount of collected data. Due to changes in the way Moore's Law computing performance gains have been realized in the past decade, an aggressive program of R&D is needed to ensure that the computing capability of CMS will be up to the task of collecting and analyzing this data.

Malaria and fetal growth alterations in the 3(rd) trimester of pregnancy

DEFF Research Database (Denmark)

Schmiegelow, Christentze; Minja, Daniel Thomas; Oesterholt, Mayke

2013-01-01

Pregnancy associated malaria is associated with decreased birth weight, but in-utero evaluation of fetal growth alterations is rarely performed. The objective of this study was to investigate malaria induced changes in fetal growth during the 3(rd) trimester using trans-abdominal ultrasound....

3rd Circuit hints it may reconsider McNemar reasoning.

Science.gov (United States)

1997-10-17

The [name removed] v. The Disney Store ruling is under criticism and the 3rd U.S. Circuit Court of Appeals may reconsider its 1996 decision to not allow employees who receive disability benefits to sue under the Americans with Disabilities Act (ADA). A panel of 3rd Circuit judges, working on [name removed] v. American Sterilizer Co., asserts that the [name removed] decision should not be used to assume that an individual's ADA claims are barred because of prior representations of disability. [Name removed] is suing American Sterilizer under the retaliation provisions of the ADA. Other courts are criticizing the [name removed] decision, including the District of Columbia Court in [name removed] v. Washington Metropolitan Area Transit Authority. The [name removed] court assets that a statement made in the context of a disability application does not preclude an ADA claim brought by a worker for illegal discrimination because the ADA and the Social Security Act differ in their statutory intent. AIDS advocates state that the [name removed] decision places a plaintiff in the position of having to choose between asserting a legal right or maintaining an income. Alan Epstein, who represented [name removed], is pleased by the criticism but explains that [name removed], who died this summer, will not be vindicated.

3rd Conference on Ignition Systems for Gasoline Engines

CERN Document Server

Sens, Marc

2017-01-01

The volume includes selected and reviewed papers from the 3rd Conference on Ignition Systems for Gasoline Engines in Berlin in November 2016. Experts from industry and universities discuss in their papers the challenges to ignition systems in providing reliable, precise ignition in the light of a wide spread in mixture quality, high exhaust gas recirculation rates and high cylinder pressures. Classic spark plug ignition as well as alternative ignition systems are assessed, the ignition system being one of the key technologies to further optimizing the gasoline engine.

Dual core processing: MRB1 is an emerging kinetoplast RNA editing complex

Czech Academy of Sciences Publication Activity Database

Hashimi, Hassan; Zimmer, S.L.; Ammerman, M. L.; Read, L. K.; Lukeš, Julius

2013-01-01

Roč. 29, č. 2 (2013), s. 91-99 ISSN 1471-4922 R&D Projects: GA ČR GAP305/12/2261; GA ČR GA204/09/1667 Institutional support: RVO:60077344 Keywords : kinetoplastida * trypanosome * RNA editing * protein complexes * RECC * MRB1 Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 6.217, year: 2013 http://www.sciencedirect.com/science/article/pii/S1471492212001985

R&D Incentives for Neglected Diseases

Science.gov (United States)

Dimitri, Nicola

2012-01-01

Neglected diseases are typically characterized as those for which adequate drug treatment is lacking, and the potential return on effort in research and development (R&D), to produce new therapies, is too small for companies to invest significant resources in the field. In recent years various incentives schemes to stimulate R&D by pharmaceutical firms have been considered. Broadly speaking, these can be classified either as ‘push’ or ‘pull’ programs. Hybrid options, that include push and pull incentives, have also become increasingly popular. Supporters and critics of these various incentive schemes have argued in favor of their relative merits and limitations, although the view that no mechanism is a perfect fit for all situations appears to be widely held. For this reason, the debate on the advantages and disadvantages of different approaches has been important for policy decisions, but is dispersed in a variety of sources. With this in mind, the aim of this paper is to contribute to the understanding of the economic determinants behind R&D investments for neglected diseases by comparing the relative strength of different incentive schemes within a simple economic model, based on the assumption of profit maximizing firms. The analysis suggests that co-funded push programs are generally more efficient than pure pull programs. However, by setting appropriate intermediate goals hybrid incentive schemes could further improve efficiency. PMID:23284648

R&D incentives for neglected diseases.

Directory of Open Access Journals (Sweden)

Nicola Dimitri

Full Text Available Neglected diseases are typically characterized as those for which adequate drug treatment is lacking, and the potential return on effort in research and development (R&D, to produce new therapies, is too small for companies to invest significant resources in the field. In recent years various incentives schemes to stimulate R&D by pharmaceutical firms have been considered. Broadly speaking, these can be classified either as 'push' or 'pull' programs. Hybrid options, that include push and pull incentives, have also become increasingly popular. Supporters and critics of these various incentive schemes have argued in favor of their relative merits and limitations, although the view that no mechanism is a perfect fit for all situations appears to be widely held. For this reason, the debate on the advantages and disadvantages of different approaches has been important for policy decisions, but is dispersed in a variety of sources. With this in mind, the aim of this paper is to contribute to the understanding of the economic determinants behind R&D investments for neglected diseases by comparing the relative strength of different incentive schemes within a simple economic model, based on the assumption of profit maximizing firms. The analysis suggests that co-funded push programs are generally more efficient than pure pull programs. However, by setting appropriate intermediate goals hybrid incentive schemes could further improve efficiency.

R&D incentives for neglected diseases.

Science.gov (United States)

Dimitri, Nicola

2012-01-01

Neglected diseases are typically characterized as those for which adequate drug treatment is lacking, and the potential return on effort in research and development (R&D), to produce new therapies, is too small for companies to invest significant resources in the field. In recent years various incentives schemes to stimulate R&D by pharmaceutical firms have been considered. Broadly speaking, these can be classified either as 'push' or 'pull' programs. Hybrid options, that include push and pull incentives, have also become increasingly popular. Supporters and critics of these various incentive schemes have argued in favor of their relative merits and limitations, although the view that no mechanism is a perfect fit for all situations appears to be widely held. For this reason, the debate on the advantages and disadvantages of different approaches has been important for policy decisions, but is dispersed in a variety of sources. With this in mind, the aim of this paper is to contribute to the understanding of the economic determinants behind R&D investments for neglected diseases by comparing the relative strength of different incentive schemes within a simple economic model, based on the assumption of profit maximizing firms. The analysis suggests that co-funded push programs are generally more efficient than pure pull programs. However, by setting appropriate intermediate goals hybrid incentive schemes could further improve efficiency.

The DAΦNE 3RD harmonic cavity

International Nuclear Information System (INIS)

Alesini, D.; Boni, R.; Clozza, A.; Gallo, A.; Guiducci, S.; Marcellini, F.; Migliorati, M.; Palumbo, L.; Pellegrino, L.; Sgamma, F.; Zobov, M.

2001-01-01

The installation of a passive 3rd harmonic cavity in both the e + and e - rings of the Frascati Φ-factory DAΦNE has been decided in order to improve the Touschek lifetime by increasing the bunch length. The implications of the RF harmonic system on the beam dynamics, in particular those related to the gap in the bunch filling pattern, have been carefully studied by means of analytical and numerical tools. A single-cell cavity incorporating a ferrite ring for the HOM damping has been designed through the extensive use of MAFIA and HFSS simulation codes. One cavity prototype has been built and extensively bench tested, while the fabrication of the two final cavities is almost completed. A description of the design and construction activities, and a set of experimental measurements are reported in this paper

Graphics workflow optimization when editing standard tasks using modern graphics editing programs

OpenAIRE

Khabirova, Maja

2012-01-01

This work focuses on the description and characteristics of common problems which graphic designers face daily when working for advertising agencies. This work describes tasks and organises them according to the type of graphic being processed and the types of output. In addition, this work describes the ways these common tasks can be completed using modern graphics editing software. It also provides a practical definition of a graphic designer and graphic agency. The aim of this work is to m...

The First Mediterranean Seminar on Science Writing, Editing and Publishing, Sarajevo, December 2-3, 2016.

Science.gov (United States)

Masic, Izet; Donev, Doncho; Sinanovic, Osman; Jakovljevic, Miro; Zerem, Enver; Milosevic, Dejan B; Gajovic, Srecko; Gasparyan, Armen Yuri; Sokolovic, Sekib; Salkic, Nermin; Uzunovic, Selma; Dobric, Silva; Kurti, Floreta; Begic, Edin; Kurtcehajic, Admir

2016-12-01

The First Mediterranean Seminar on Science Writing, Editing & Publishing (SWEP 2016) was held in Sarajevo, Bosnia & Herzegovina from 2nd to 3rd December 2016. It was organized by Academy of Medical Sciences of Bosnia and Herzegovina, running concurrent sessions as part of its Annual Meeting titled " "Days of AMNuBiH - Theory and Practice in Science Communication and Scientometrics". Hotel Bosnia in the city centre was the chosen venue. On the first day, nineteen presentations on various issues of science writing and publication ethics were delivered by speakers from Croatia, Serbia, Macedonia, Albania, Bosnia & Herzegovina and the UK (Asim Kurjak, Milivoj Boranić, Doncho Donev, Osman Sinanović, Miro Jakovljević, Enver Zerem, Dejan Milošević, Silva Dobrić, Srećko Gajović, Izet Mašić, Armen Yuri Gasparyan, Šekib Sokolović, Nermin Salkić, Selma Uzunović, Admir Kurtčehajić, Edin Begić and Floreta Kurti). Each presentation had a take-home message for novice and seasoned authors, encountering numerous problems in non-Anglophone research environment. Lecturers, who were internationally recognized editors of regional journals, generously shared their experience of adhering to the best ethical guidance. Elegant presentations by Srećko Gajović (Editor-in-Chief of the Croatian Medical Journal) and Armen Yuri Gasparyan (past Chief Editor of the European Science Editing) showcased their accomplishments that strengthened ties between authors from all over the world. Gasparyan reflected on educational resources of editorial associations, such as the International Committee of Medical Journal Editors (ICMJE) and the Committee on Publication Ethics (COPE), and called not just to declare the adherence to, but also to enforce their ethical guidance in daily practice. Editors of Medical Archives, Croatian Medica Journal, Vojnosanitetski Pregled, Psychiatria Danubina, Acta Informatica Medica, Materia Socio-Medica, The Donald School Journal of Ultrasound in Obstretics

Status of the French R/D program on the severe accident issue to develop Gen IV SFRs - 15373

International Nuclear Information System (INIS)

Serre, F.; Bertrand, F.; Journeau, C.; Suteau, C.; Verwaede, D.; Schmitt, D.; Farges, B.

2015-01-01

The ASTRID reactor (Advanced Sodium Technological Reactor for Industrial Demonstration) is a technological demonstrator designed by the CEA with its industrial partners, with very high levels of requirements. In the ASTRID project, the safety objectives are to prevent core melting, in particular by the development of an innovative core with complementary safety prevention devices, and to enhance the reactor resistance to severe accident by design. To mitigate the consequences of hypothetical core melting situations, specific dispositions or mitigation devices will be added to the core and to the reactor. It is also required to provide a robust safety demonstration (with high level of confidence). Therefore a new approach for severe accident issue has been defined: to the well-known 'lines of defense' method, a 'lines of mitigation' method is added. To meet these ASTRID, or future SFR, requirements, a large R/D program was launched in the Severe Accident domain, with a large number of partners. This paper will present the status of the CEA R/D related to the SFR Severe Accident issue, the collaboration framework (with industrial partners and R/D foreign organizations), and the future R/D plans to support the ASTRID project and possible developments for future Gen IV commercial SFR. (authors)

FY2013 Energy Storage R&D Progress Report

Energy Technology Data Exchange (ETDEWEB)

none,

2014-02-01

The FY 2013 Progress Report for Energy Storage R&D focuses on advancing the development of batteries to enable a large market penetration of hybrid and electric vehicles. Program targets focus on overcoming technical barriers to enable market success including: (1) significantly reducing battery cost, (2) increasing battery performance (power, energy, durability), (3) reducing battery weight & volume, and (4) increasing battery tolerance to abusive conditions such as short circuit, overcharge, and crush.

Guidelines for chemical peeling in Japan (3rd edition).

Science.gov (United States)

2012-04-01

Chemical peeling may be defined as the therapies, procedures and techniques used for the treatment of certain cutaneous diseases or conditions, and for aesthetic improvement. The procedures include the application of one or more chemical agents to the skin. Chemical peeling has been very popular in both medical and aesthetic fields. Because neither its scientific background is well understood nor a systematic approach established, medical and social problems have taken place. This prompted us to establish and distribute a standard guideline of care for chemical peeling. Previous guidelines such as the 2001 and 2004 versions included minimum standards of care such as indications, chemicals, applications, and any associated precautions, including post-peeling care. The principles in this updated version of chemical peeling are as follows: (i) chemical peeling should be performed under the strict technical control and responsibility of a physician; (ii) the physician should have sufficient knowledge of the structure and physiology of the skin and subcutaneous tissues, and understand the mechanisms of wound-healing induced by chemical peeling; (iii) the physician should be board-certified in an appropriate specialty such as dermatology; and (iv) the ultimate judgment regarding the appropriateness of any specific chemical peeling procedure must be made by the physician while considering all standard therapeutic protocols, which should be presented to each individual patient. Keeping these concepts in mind, this new version of the guidelines includes a more scientific and detailed approach from the viewpoint of evidence-based medicine. © 2011 Japanese Dermatological Association.

The effect of introducing increased-reliability-risk electronic components into 3rd generation telecommunications systems

International Nuclear Information System (INIS)

Salmela, Olli

2005-01-01

In this paper, the dependability of 3rd generation telecommunications network systems is studied. Special attention is paid to a case where increased-reliability-risk electronic components are introduced to the system. The paper consists of three parts: First, the reliability data of four electronic components is considered. This includes statistical analysis of the reliability test data, thermo-mechanical finite element analysis of the printed wiring board structures, and based on those, a field reliability estimate of the components is constructed. Second, the component level reliability data is introduced into the network element reliability analysis. This is accomplished by using a reliability block diagram technique and Monte Carlo simulation of the network element. The end result of the second part is a reliability estimate of the network element with and without the high-risk component. Third, the whole 3rd generation network having multiple network elements is analyzed. In this part, the criticality of introducing high-risk electronic components into a 3rd generation telecommunications network is considered

The effect of introducing increased-reliability-risk electronic components into 3rd generation telecommunications systems

Energy Technology Data Exchange (ETDEWEB)

Salmela, Olli [Nokia Networks, P.O. Box 301, 00045 Nokia Group (Finland)]. E-mail: olli.salmela@nokia.com

2005-08-01

In this paper, the dependability of 3rd generation telecommunications network systems is studied. Special attention is paid to a case where increased-reliability-risk electronic components are introduced to the system. The paper consists of three parts: First, the reliability data of four electronic components is considered. This includes statistical analysis of the reliability test data, thermo-mechanical finite element analysis of the printed wiring board structures, and based on those, a field reliability estimate of the components is constructed. Second, the component level reliability data is introduced into the network element reliability analysis. This is accomplished by using a reliability block diagram technique and Monte Carlo simulation of the network element. The end result of the second part is a reliability estimate of the network element with and without the high-risk component. Third, the whole 3rd generation network having multiple network elements is analyzed. In this part, the criticality of introducing high-risk electronic components into a 3rd generation telecommunications network is considered.

Risk taking and effective R&D management.

Science.gov (United States)

Banholzer, William F; Vosejpka, Laura J

2011-01-01

Several key strategies can be used to manage the risk associated with innovation to create maximum value. These include balancing the timing of investments versus cash flows, management of fads, prioritization across the company, savvy portfolio management, and a system of metrics that measure real success. Successful R&D managers will do whatever is necessary to manage the risks associated with an R&D program and stick to their long-term strategy.

Break Breast Cancer Addiction by CRISPR/Cas9 Genome Editing.

Science.gov (United States)

Yang, Haitao; Jaeger, MariaLynn; Walker, Averi; Wei, Daniel; Leiker, Katie; Weitao, Tao

2018-01-01

Breast cancer is the leading diagnosed cancer for women globally. Evolution of breast cancer in tumorigenesis, metastasis and treatment resistance appears to be driven by the aberrant gene expression and protein degradation encoded by the cancer genomes. The uncontrolled cancer growth relies on these cellular events, thus constituting the cancerous programs and rendering the addiction towards them. These programs are likely the potential anticancer biomarkers for Personalized Medicine of breast cancer. This review intends to delineate the impact of the CRSPR/Cas-mediated genome editing in identification and validation of these anticancer biomarkers. It reviews the progress in three aspects of CRISPR/Cas9-mediated editing of the breast cancer genomes: Somatic genome editing, transcription and protein degradation addictions.

3rd International Conference Nanotechnology and Nanomaterials

CERN Document Server

Yatsenko, Leonid

2016-01-01

This book presents some of the latest achievements in nanotechnology and nanomaterials from leading researchers in Ukraine, Europe, and beyond. It features contributions from participants in the 3rd International Science and Practice Conference Nanotechnology and Nanomaterials (NANO2015) held in Lviv, Ukraine on August 26-30, 2015. The International Conference was organized jointly by the Institute of Physics of the National Academy of Sciences of Ukraine, University of Tartu (Estonia), Ivan Franko National University of Lviv (Ukraine), University of Turin (Italy), Pierre and Marie Curie University (France), and European Profiles A.E. (Greece). Internationally recognized experts from a wide range of universities and research institutions share their knowledge and key results on topics ranging from nanooptics, nanoplasmonics, and interface studies to energy storage and biomedical applications. Presents cutting-edge advances in nanocomposites and carbon and silicon-based nanomaterials for a wide range of engine...

Effectiveness of public support for R&D and entrepreneurship

NARCIS (Netherlands)

Mohnen, P.

2017-01-01

The papers by Dortet-Bernadet and Sicsic and by Redor in this issue examine respectively the success of R&D financial support programs in stimulating private R&D and the success of subsidized start-ups for the unemployed in creating long-lasting firms. Both papers focus on small French firms. Both

U.S. FUEL CYCLE TECHNOLOGIES R&D PROGRAM FOR NEXT GENERATION NUCLEAR MATERIALS MANAGEMENT

Directory of Open Access Journals (Sweden)

M.C. MILLER

2013-11-01

Full Text Available The U.S. Department of Energy's Fuel Cycle Technologies R&D program under the Office of Nuclear Energy is working to advance technologies to enhance both the existing and future fuel cycles. One thrust area is in developing enabling technologies for next generation nuclear materials management under the Materials Protection, Accounting and Control Technologies (MPACT Campaign where advanced instrumentation, analysis and assessment methods, and security approaches are being developed under a framework of Safeguards and Security by Design. An overview of the MPACT campaign's activities and recent accomplishments is presented along with future plans.

Proceedings of the 3rd Symposium on Engineering Sciences

International Nuclear Information System (INIS)

Ahmed, J.; Rizvi, S.Z.H.; Ahmad, R.; Saleem, M.

2010-01-01

The 3rd symposium on engineering sciences was held from March 10-12, 2010 in Lahore, Pakistan. More than twenty academic institutions and six industries participated in this conference. The foreign and Pakistani experts delivered their keynotes talk, contributor lectures and poster presentation on the conference topics. In three days of the symposium, Fifty four papers presented on different topics of Engineering Sciences including chemical engineering, energy engineering, metallurgy engineering, material engineering and electrical engineering. This symposium provided an ideal opportunity for exchange of information amongst scientists, engineers and researchers from all over Pakistan and other countries of the world. (A.B)

3rd Developers@CERN Forum

CERN Multimedia

CERN. Geneva

2017-01-01

It's about U and I !   The Developers@CERN Forum is an event by developers, for developers, aimed at promoting knowledge and experience sharing. This edition will take place at the IT Amphitheatre, on the 13th, 14th and 15th of February afternoons. It will consist of a series of short presentations and workshops. The topic for this conference will be Frontend & User interfaces. Have you got an idea for a presentation or workshop? Then, tell us about it (deadline on 27th of January). Registration will open in November. Please subscribe to developers-forum-announce@cern.ch mailing list for further information. This event will be made by developers for developers. We are counting on your presence, but also on your contributions! To learn more about the initiative, read the CERN Bulletin article. Organization You can get in touch us at developers-forum-organizers@cern.ch.

Cloud Properties of CERES-MODIS Edition 4 and CERES-VIIRS Edition 1

Science.gov (United States)

Sun-Mack, Sunny; Minnis, Patrick; Chang, Fu-Lung; Hong, Gang; Arduini, Robert; Chen, Yan; Trepte, Qing; Yost, Chris; Smith, Rita; Brown, Ricky;

The Extent of mRNA Editing Is Limited in Chicken Liver and Adipose, but Impacted by Tissular Context, Genotype, Age, and Feeding as Exemplified with a Conserved Edited Site in COG3

Directory of Open Access Journals (Sweden)

Pierre-François Roux

2016-02-01

Full Text Available RNA editing is a posttranscriptional process leading to differences between genomic DNA and transcript sequences, potentially enhancing transcriptome diversity. With recent advances in high-throughput sequencing, many efforts have been made to describe mRNA editing at the transcriptome scale, especially in mammals, yielding contradictory conclusions regarding the extent of this phenomenon. We show, by detailed description of the 25 studies focusing so far on mRNA editing at the whole-transcriptome scale, that systematic sequencing artifacts are considered in most studies whereas biological replication is often neglected and multi-alignment not properly evaluated, which ultimately impairs the legitimacy of results. We recently developed a rigorous strategy to identify mRNA editing using mRNA and genomic DNA sequencing, taking into account sequencing and mapping artifacts, and biological replicates. We applied this method to screen for mRNA editing in liver and white adipose tissue from eight chickens and confirm the small extent of mRNA recoding in this species. Among the 25 unique edited sites identified, three events were previously described in mammals, attesting that this phenomenon is conserved throughout evolution. Deeper investigations on five sites revealed the impact of tissular context, genotype, age, feeding conditions, and sex on mRNA editing levels. More specifically, this analysis highlighted that the editing level at the site located on COG3 was strongly regulated by four of these factors. By comprehensively characterizing the mRNA editing landscape in chickens, our results highlight how this phenomenon is limited and suggest regulation of editing levels by various genetic and environmental factors.

Editing faces in videos

OpenAIRE

Amberg, Brian

2011-01-01

Editing faces in movies is of interest in the special effects industry. We aim at producing effects such as the addition of accessories interacting correctly with the face or replacing the face of a stuntman with the face of the main actor. The system introduced in this thesis is based on a 3D generative face model. Using a 3D model makes it possible to edit the face in the semantic space of pose, expression, and identity instead of pixel space, and due to its 3D nature allows...

Fan edits and the legacy of The Phantom Edit

Directory of Open Access Journals (Sweden)

Joshua Wille

2014-09-01

Full Text Available A fan edit can generally be defined as an alternative version of a film or television text created by a fan. It offers a different viewing experience, much as a song remix offers a different listening experience. The contemporary wave of fan edits has emerged during the remix zeitgeist of digital media and at a time when digital video editing technology has become more affordable and popular. The increasing number of alternative versions of films and the works of revisionist Hollywood filmmakers such as George Lucas have contributed to a greater public understanding of cinema as a fluid medium instead of one that exists in a fixed form. The Phantom Edit (2000, a seminal fan edit based on Lucas's Star Wars Episode I: The Phantom Menace (1999, inspired new ranks of fan editors. However, critics have misunderstood fan edits as merely the work of disgruntled fans. In order to provide a critical and historical basis for studies in fan editing as a creative practice, I examine previous interpretations of fan edits in the context of relevant contemporary works, and I use an annotated chronology of The Phantom Edit to trace its influence on subsequent fan editing communities and uncover their relationship with intellectual property disputes.

CRISPR–Cas system enables fast and simple genome editing of industrial Saccharomyces cerevisiae strains

Directory of Open Access Journals (Sweden)

Vratislav Stovicek

2015-12-01

Full Text Available There is a demand to develop 3rd generation biorefineries that integrate energy production with the production of higher value chemicals from renewable feedstocks. Here, robust and stress-tolerant industrial strains of Saccharomyces cerevisiae will be suitable production organisms. However, their genetic manipulation is challenging, as they are usually diploid or polyploid. Therefore, there is a need to develop more efficient genetic engineering tools. We applied a CRISPR–Cas9 system for genome editing of different industrial strains, and show simultaneous disruption of two alleles of a gene in several unrelated strains with the efficiency ranging between 65% and 78%. We also achieved simultaneous disruption and knock-in of a reporter gene, and demonstrate the applicability of the method by designing lactic acid-producing strains in a single transformation event, where insertion of a heterologous gene and disruption of two endogenous genes occurred simultaneously. Our study provides a foundation for efficient engineering of industrial yeast cell factories. Keywords: CRISPR–Cas9, Genome editing, Industrial yeast, Biorefineries, Chemical production

3rd Computer Science On-line Conference

CERN Document Server

Senkerik, Roman; Oplatkova, Zuzana; Silhavy, Petr; Prokopova, Zdenka

2014-01-01

This book is based on the research papers presented in the 3rd Computer Science On-line Conference 2014 (CSOC 2014).   The conference is intended to provide an international forum for discussions on the latest high-quality research results in all areas related to Computer Science. The topics addressed are the theoretical aspects and applications of Artificial Intelligences, Computer Science, Informatics and Software Engineering.   The authors provide new approaches and methods to real-world problems, and in particular, exploratory research that describes novel approaches in their field. Particular emphasis is laid on modern trends in selected fields of interest. New algorithms or methods in a variety of fields are also presented.   This book is divided into three sections and covers topics including Artificial Intelligence, Computer Science and Software Engineering. Each section consists of new theoretical contributions and applications which can be used for the further development of knowledge of everybod...

Results from the UK 3rd generation programme: Albion

Science.gov (United States)

McEwen, R. K.; Axcell, C.; Knowles, P.; Hoade, K. P.; Wilson, M.; Dennis, P. N. J.; Backhouse, P.; Gordon, N. T.

2008-10-01

Following the development of 1st Generation systems in the 1970s, thermal imaging has been in service with the UK armed forces for over 25 years and has proven itself to be a battle winning technology. More recently the wider accessibility to similar technologies within opposing forces has reduced the military advantage provided by these 1st Generation systems and a clear requirement has been identified by the UK MOD for thermal imaging sensors providing increased detection, recognition and identification (DRI) ranges together with a simplified logistical deployment burden and reduced through-life costs. In late 2005, the UK MOD initiated a programme known as "Albion" to develop high performance 3rd Generation single waveband infrared detectors to meet this requirement. At the same time, under a separate programme supporting higher risk technology, a dual waveband infrared detector was also developed. The development phase of the Albion programme has now been completed and prototype detectors are now available and have been integrated into demonstration thermal imaging cameras. The Albion programme has now progressed into the second phase, incorporating both single and dual waveband devices, focussing on low rate initial production (LRIP) and qualification of the devices for military applications. All of the detectors have been fabricated using cadmium mercury telluride material (CMT), grown by metal organic vapour phase epitaxy (MOVPE) on low cost, gallium arsenide (GaAs) substrates and bump bonded to the silicon read out circuit (ROIC). This paper discusses the design features of the 3rd Generation detectors developed in the UK together with the results obtained from the prototype devices both in the laboratory and when integrated into field deployable thermal imaging cameras.

Do we need a definition of games?

DEFF Research Database (Denmark)

Eichberg, Henning

2016-01-01

Anmeldelse og diskussion af Bernard Suits (2014): The Grasshopper. Games, Life, and Utopia. 3rd edition. Peterborough, Ontario: Broadview......Anmeldelse og diskussion af Bernard Suits (2014): The Grasshopper. Games, Life, and Utopia. 3rd edition. Peterborough, Ontario: Broadview...

3rd IFToMM Symposium on Mechanism Design for Robotics

CERN Document Server

Ceccarelli, Marco

2015-01-01

This volume contains the Proceedings of the 3rd IFToMM Symposium on Mechanism Design for Robotics, held in Aalborg, Denmark, 2-4 June, 2015. The book contains papers on recent advances in the design of mechanisms and their robotic applications. It treats the following topics: mechanism design, mechanics of robots, parallel manipulators, actuators and their control, linkage and industrial manipulators, innovative mechanisms/robots and their applications, among others. The book can be used by researchers and engineers in the relevant areas of mechanisms, machines and robotics.

Teaching Newton's 3rd law of motion using learning by design approach

Science.gov (United States)

Aquino, Jiezel G.; Caliguid, Mariel P.; Buan, Amelia T.; Magsayod, Joy R.; Lahoylahoy, Myrna E.

2018-01-01

This paper presents the process and implementation of Learning by Design Approach in teaching Newton's 3rd Law of Motion. A lesson activity from integrative STEM education was adapted, modified and enhanced through pilot testing. After revisions, the implementation was done to one class. The respondent's prior knowledge was first assessed by a pretest. PPIT (present the scenario, plan, implement and test) was the framework followed in the implementation of Learning by Design. Worksheets were then utilized to measure their conceptual understanding and perception. A score guide was also used to evaluate the student's output. Paired t-test analysis showed that there is a significant difference in the pretest and posttest achievement scores. This implies that the performance of the students have improved during the implementation of the Learning by Design. The Analysis of variance also depicts that the low, average and high benefited in the Learning by Design approach. The results of this study suggests that Learning by Design is an effective approach in teaching Newton's 3rd Law of Motion and thus be used in a Science classroom.

The 3"r"d inter laboratory comparison in the determination of elements in foodstuff with neutron activation analysis method

International Nuclear Information System (INIS)

Muji Wiyono; Dadong Iskandar; Wahyudi

2010-01-01

The 3"r"d inter laboratory comparison in the determination of elements in the foodstuff with NAA method held by PTBIN-BATAN Laboratory has been carried out. Six laboratories in BATAN were participated in the program with each code were: Lab. 01, Lab. 02, Lab. 03, Lab. 04, Lab. 05 and Lab. 06. Lab KKL PTKMR-BATAN was a participant with Lab. 06 code number. The received samples of foodstuff were prepared and irradiated in the RS-03 rabbit system of GA. Siwabessy multi purpose reactor. The irradiated samples were counted by using gamma spectrometer with HPGe detector to determine the content of elements. Result of the analysis was reported to the coordinator to be evaluated whether the sample was passed or rejected. Result of the coordinator laboratory evaluated that, 9 elements identified by Lab. KKL PTKMR-BATAN had four elements such as; Al, K, Cu and Se were passed (accepted) and other elements such as; Mn, Na, Ca, Fe and Zn were rejected. The elements number that passed in the 3"r"d inter laboratory comparison was less than those of earlier inter laboratory comparison, this was due to elemental content in the analyzed samples was very low. (author)

FY2016 Advanced Batteries R&D Annual Progress Report

Energy Technology Data Exchange (ETDEWEB)

None, None

2017-08-31

The Advanced Batteries research and development (R&D) subprogram within the DOE Vehicle Technologies Office (VTO) provides support and guidance for projects focusing on batteries for plug-in electric vehicles. Program targets focus on overcoming technical barriers to enable market success including: (1) significantly reducing battery cost, (2) increasing battery performance (power, energy, durability), (3) reducing battery weight & volume, and (4) increasing battery tolerance to abusive conditions such as short circuit, overcharge, and crush. This report describes the progress made on the research and development projects funded by the Battery subprogram in 2016. This section covers the Vehicle Technologies Office overview; the Battery subprogram R&D overview; Advanced Battery Development project summaries; and Battery Testing, Analysis, and Design project summaries. It also includes the cover and table of contents.

Participants to the 3rd HEP Information Resources Summit, 6-7 May 2009

CERN Multimedia

Fermilab, Photo Service

2009-01-01

The broad theme of the 3rd HEP Information Resources Summit was "Collaboration between Information Services." As HEP increasingly borders fields such as instrumentation and astrophysics, it was discussed what potential interrelationships and communication this group have to serve this broader research community seamlessly.

Handbook for designing roadways for the aging population.

Science.gov (United States)

2014-06-01

The original Older Driver Highway Design Handbook was published by FHWA in 1998 (FHWA-RD-97-135). The : 2nd edition, titled Highway Design Handbook for Older Drivers and Pedestrians (FHWA-RD-01-103) was published in : 2001. This 3rd edition, under a ...

FY2015 Energy Storage R&D Annual Progress Report

Energy Technology Data Exchange (ETDEWEB)

None, None

2016-04-30

The Energy Storage research and development (R&D) subprogram within the DOE Vehicle Technologies Office (VTO) provides support and guidance for projects focusing on batteries for plug-in electric vehicles. Program targets focus on overcoming technical barriers to enable market success including: (1) significantly reducing battery cost, (2) increasing battery performance (power, energy, durability), (3) reducing battery weight & volume, and (4) increasing battery tolerance to abusive conditions such as short circuit, overcharge, and crush.

The Blue Book. Accounting, Recordkeeping, and Reporting by Postsecondary Educational Institutions for Federally Funded Student Financial Aid Programs. [1999 Edition.

Science.gov (United States)

Department of Education, Washington, DC.

This guide is intended to provide guidance to college and university business office personnel who handle recordkeeping, accounting, and other fiscal reporting functions for federal Title IV financial aid programs, as authorized by the Higher Education Act of 1965, as amended. This edition emphasizes the benefits and challenges of electronic…

Foundational Skills to Support Reading for Understanding in Kindergarten through 3rd Grade. Educator's Practice Guide. NCEE 2016-4008

Science.gov (United States)

Foorman, Barbara; Beyler, Nicholas; Borradaile, Kelley; Coyne, Michael; Denton, Carolyn A.; Dimino, Joseph; Furgeson, Joshua; Hayes, Lynda; Henke, Juliette; Justice, Laura; Keating, Betsy; Lewis, Warnick; Sattar, Samina; Streke, Andrei; Wagner, Richard; Wissel, Sarah

2016-01-01

The goal of this practice guide is to offer educators specific, evidence-based recommendations for teaching foundational reading skills to students in kindergarten through 3rd grade. This guide is a companion to the existing practice guide, "Improving Reading Comprehension in Kindergarten Through 3rd Grade", and as a set, these guides…

3rd International Conference on Movement, Health and Exercise 2016

CERN Document Server

Cheong, Jadeera; Usman, Juliana; Ahmad, Mohd; Razman, Rizal; Selvanayagam, Victor

2017-01-01

This volume presents the proceedings of the 3rd International Conference on Movement, Health and Exercise 2016 (MoHE2016). The conference was jointly organized by the Biomedical Engineering Department and Sports Centre, University of Malaya. It was held in Malacca, from 28-30 September 2016. MoHE 2016 provided a good opportunity for speakers and participants to actively discuss about recent developments in a wide range of topics in the area of sports and exercise science. In total, 83 presenters and 140 participants took part in this successful conference. .

Report on Workshop on Future Directions for Accelerator R&D at Fermilab

Energy Technology Data Exchange (ETDEWEB)

Shiltsev, V.; Church, M.; Spentzouris, P.; Chou, W.; /Fermilab

2009-09-01

Accelerator R&D has played a crucial role in enabling scientific discovery in the past century and will continue to play this role in the years to come. In the U.S., the Office of High Energy Physics of DOE's Office of Science is developing a plan for national accelerator R&D stewardship. Fermilab undertakes accelerator research, design, and development focused on superconducting radio-frequency (RF), superconducting magnet, beam cooling, and high intensity proton technologies. In addition, the Lab pursues comprehensive integrated theoretical concepts and simulations of complete future facilities on both the energy and intensity frontiers. At present, Fermilab (1) supplies integrated design concept and technology development for a multi-MW proton source (Project X) to support world-leading programs in long baseline neutrino and rare processes experiments; (2) plays a leading role in the development of ionization cooling technologies required for muon storage ring facilities at the energy (multi-TeV Muon Collider) and intensity (Neutrino Factory) frontiers, and supplies integrated design concepts for these facilities; and (3) carries out a program of advanced accelerator R&D (AARD) in the field of high quality beam sources, and novel beam manipulation techniques.

ic-cmtp3: 3rd International Conference on Competitive Materials and Technology Processes

Science.gov (United States)

2016-04-01

Competitiveness is one of the most important factors in our lives and it plays a key role in the efficiency both of organizations and societies. The more scientifically advanced and prepared organizations develop more competitive materials with better physical, chemical, and biological properties, and the leading companies apply more competitive equipment and technological processes. The aims of the 3rd International Conference on Competitive Materials and Technology Processes (ic-cmtp3), and the 1st International Symposium on Innovative Carbons and Carbon Based Materials (is-icbm1) and the 1st International Symposium on Innovative Construction Materials (is-icm1) organized alongside are the following: —Promote new methods and results of scientific research in the fields of material, biological, environmental and technological sciences; —Exchange information between the theoretical and applied sciences as well as technical and technological implementations; —Promote communication and collaboration between the scientists, researchers and engineers of different nations, countries and continents. Among the major fields of interest are advanced and innovative materials with competitive characteristics, including mechanical, physical, chemical, biological, medical and thermal, properties and extreme dynamic strength. Their crystalline, nano - and micro-structures, phase transformations as well as details of their technological processes, tests and measurements are also in the focus of the ic-cmtp3 conference and the is-scbm1 and is-icm1 symposia. Multidisciplinary applications of material science and the technological problems encountered in sectors like ceramics, glasses, thin films, aerospace, automotive and marine industries, electronics, energy, construction materials, medicine, biosciences and environmental sciences are of particular interest. In accordance with the program of the ic-cmtp3 conference and is-icbm1 and is-icm1 symposia we have received more

3rd International School of Trigger and Data Acquisition - Cracow (Poland), 1 – 8 February 2012

CERN Multimedia

Yi Ling

2011-01-01

After two successful editions of the International School of Trigger and Data Acquisition (ISOTDAQ), the ISOTDAQ 2012 is the third of a series of this International School dedicated to introduce MSc and PhD students to the arts and crafts of triggering and acquiring data for physics experiments. The school will be held from 1 – 8 February 2012 in the Cracow University of Technology and Institute of Nuclear Physics, Cracow, Poland.  The school provides an up-to-date overview of the basic instruments and methodologies used in high energy physics, spanning from small experiences in lab to the very large LHC experiments, spotting the main building blocks as well as the different solutions and architectures at different levels of complexity. The main topics of the school include the basics of Data Acquisition (DAQ) programming concepts (e.g. threaded programming, data storage, networking, IO programming), hardware bus systems (VME bus, PCI), Trigger logic and Hardware (NIM). PC based readout...

Mojo Hand, a TALEN design tool for genome editing applications.

Science.gov (United States)

Neff, Kevin L; Argue, David P; Ma, Alvin C; Lee, Han B; Clark, Karl J; Ekker, Stephen C

2013-01-16

Recent studies of transcription activator-like (TAL) effector domains fused to nucleases (TALENs) demonstrate enormous potential for genome editing. Effective design of TALENs requires a combination of selecting appropriate genetic features, finding pairs of binding sites based on a consensus sequence, and, in some cases, identifying endogenous restriction sites for downstream molecular genetic applications. We present the web-based program Mojo Hand for designing TAL and TALEN constructs for genome editing applications (http://www.talendesign.org). We describe the algorithm and its implementation. The features of Mojo Hand include (1) automatic download of genomic data from the National Center for Biotechnology Information, (2) analysis of any DNA sequence to reveal pairs of binding sites based on a user-defined template, (3) selection of restriction-enzyme recognition sites in the spacer between the TAL monomer binding sites including options for the selection of restriction enzyme suppliers, and (4) output files designed for subsequent TALEN construction using the Golden Gate assembly method. Mojo Hand enables the rapid identification of TAL binding sites for use in TALEN design. The assembly of TALEN constructs, is also simplified by using the TAL-site prediction program in conjunction with a spreadsheet management aid of reagent concentrations and TALEN formulation. Mojo Hand enables scientists to more rapidly deploy TALENs for genome editing applications.

Mojo Hand, a TALEN design tool for genome editing applications

Directory of Open Access Journals (Sweden)

Neff Kevin L

2013-01-01

Full Text Available Abstract Background Recent studies of transcription activator-like (TAL effector domains fused to nucleases (TALENs demonstrate enormous potential for genome editing. Effective design of TALENs requires a combination of selecting appropriate genetic features, finding pairs of binding sites based on a consensus sequence, and, in some cases, identifying endogenous restriction sites for downstream molecular genetic applications. Results We present the web-based program Mojo Hand for designing TAL and TALEN constructs for genome editing applications (http://www.talendesign.org. We describe the algorithm and its implementation. The features of Mojo Hand include (1 automatic download of genomic data from the National Center for Biotechnology Information, (2 analysis of any DNA sequence to reveal pairs of binding sites based on a user-defined template, (3 selection of restriction-enzyme recognition sites in the spacer between the TAL monomer binding sites including options for the selection of restriction enzyme suppliers, and (4 output files designed for subsequent TALEN construction using the Golden Gate assembly method. Conclusions Mojo Hand enables the rapid identification of TAL binding sites for use in TALEN design. The assembly of TALEN constructs, is also simplified by using the TAL-site prediction program in conjunction with a spreadsheet management aid of reagent concentrations and TALEN formulation. Mojo Hand enables scientists to more rapidly deploy TALENs for genome editing applications.

3rd ACIS International Conference on Applied Computing and Information Technology

CERN Document Server

2016-01-01

This edited book presents scientific results of the 3nd International Conference on Applied Computing and Information Technology (ACIT 2015) which was held on July 12-16, 2015 in Okayama, Japan. The aim of this conference was to bring together researchers and scientists, businessmen and entrepreneurs, teachers, engineers, computer users, and students to discuss the numerous fields of computer science and to share their experiences and exchange new ideas and information in a meaningful way. Research results about all aspects (theory, applications and tools) of computer and information science, and to discuss the practical challenges encountered along the way and the solutions adopted to solve them.

PREFACE: 3rd Workshop on Theory, Modelling and Computational Methods for Semiconductors (TMCSIII)

Science.gov (United States)

Califano, Marco; Migliorato, Max; Probert, Matt

2012-05-01

These conference proceedings contain the written papers of the contributions presented at the 3rd International Conference on Theory, Modelling and Computational Methods for Semiconductor materials and nanostructures. The conference was held at the School of Electronic and Electrical Engineering, University of Leeds, Leeds, UK on 18-20 January 2012. The previous conferences in this series took place in 2010 at St William's College, York and in 2008 at the University of Manchester, UK. The development of high-speed computer architectures is finally allowing the routine use of accurate methods for calculating the structural, thermodynamic, vibrational, optical and electronic properties of semiconductors and their hetero- and nano-structures. The scope of this conference embraces modelling, theory and the use of sophisticated computational tools in semiconductor science and technology, where there is substantial potential for time-saving in R&D. Theoretical approaches represented in this meeting included: Density Functional Theory, Tight Binding, Semiempirical Pseudopotential Methods, Effective Mass Models, Empirical Potential Methods and Multiscale Approaches. Topics included, but were not limited to: Optical and Transport Properties of Quantum Nanostructures including Colloids and Nanotubes, Plasmonics, Magnetic Semiconductors, Graphene, Lasers, Photonic Structures, Photovoltaic and Electronic Devices. This workshop ran for three days, with the objective of bringing together UK and international leading experts in the theoretical modelling of Group IV, III-V and II-VI semiconductors, as well as students, postdocs and early-career researchers. The first day focused on providing an introduction and overview of this vast field, aimed particularly at students, with several lectures given by recognised experts in various theoretical approaches. The following two days showcased some of the best theoretical research carried out in the UK in this field, with several

BACODINE/3rd Interplanetary Network burst localization

International Nuclear Information System (INIS)

Hurley, K.; Barthelmy, S.; Butterworth, P.; Cline, T.; Sommer, M.; Boer, M.; Niel, M.; Kouveliotou, C.; Fishman, G.; Meegan, C.

1996-01-01

Even with only two widely separated spacecraft (Ulysses and GRO), 3rd Interplanetary Network (IPN) localizations can reduce the areas of BATSE error circles by two orders of magnitude. Therefore it is useful to disseminate them as quickly as possible following BATSE bursts. We have implemented a system which transmits the light curves of BACODINE/BATSE bursts directly by e-mail to UC Berkeley immediately after detection. An automatic e-mail parser at Berkeley watches for these notices, determines the Ulysses crossing time window, and initiates a search for the burst data on the JPL computer as they are received. In ideal cases, it is possible to retrieve the Ulysses data within a few hours of a burst, generate an annulus of arrival directions, and e-mail it out to the astronomical community by local nightfall. Human operators remain in this loop, but we are developing a fully automated routine which should remove them, at least for intense events, and reduce turn-around times to an absolute minimum. We explain the current operations, the data types used, and the speed/accuracy tradeoffs

The Elementary School Library Collection: A Guide to Books and Other Media, Phases 1-2-3. 20th Edition.

Science.gov (United States)

Homa, Linda L., Ed.; And Others

This collection development aid lists more than 10,000 titles of children's materials available in a variety of formats (in addition to print materials, the guide also includes sound recordings, video cassettes, microcomputer software programs, CD-ROM products, and videodiscs). This 20th anniversary edition contains several special features,…

Oil and Gas R&D Programs

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-03-01

This publication describes the major components of the research and development programs of the Department of Energy`s Office of Natural Gas and Petroleum Technology. These programs are commonly referred to collectively as the `Oil and Gas Program.` This document provides customers with a single source of information describing the details of the individual technology program components. This document reflects the results of a planning cycle that began in early 1996 with the development of a scenario analysis for the programs, followed by the development of the coordinated strategic plan. The technology program plans, which are the most recent products of the planning cycle, expand on the program descriptions presented in the coordinated strategic plan, and represent an initial effort to coordinate the Oil and Gas Program exploration and production programs and budgets. Each technology program plan includes a `roadmap` that summarizes the progress of the program to the present and indicates its future direction. The roadmaps describe the program drivers, vision, mission, strategies, and measures of success. Both the individual technology program plans and the strategic plan are dynamic and are intended to be updated regularly.

Photonic Network R&D Activities in Japan-Current Activities and Future Perspectives

Science.gov (United States)

Kitayama, Ken-Ichi; Miki, Tetsuya; Morioka, Toshio; Tsushima, Hideaki; Koga, Masafumi; Mori, Kazuyuki; Araki, Soichiro; Sato, Ken-Ichi; Onaka, Hiroshi; Namiki, Shu; Aoyama, Tomonori

2005-10-01

R&D activities on photonic networks in Japan are presented. First, milestones in current ongoing R&D programs supported by Japanese government agencies are introduced, including long-distance and wavelength division multiplexing (WDM) fiber transmission, wavelength routing, optical burst switching (OBS), and control-plane technology for IP backbone networks. Their goal was set to evolve a legacy telecommunications network to IP-over-WDM networks by introducing technologies for WDM and wavelength routing. We then discuss the perspectives of so-called PHASE II R&D programs for photonic networks over the next 5 years until 2010, by focusing on the report that has been recently issued by the Photonic Internet Forum (PIF), a consortium that has major carriers, telecom vendors, and Japanese academics as members. The PHASE II R&D programs should serve to establish a photonic platform to provide abundant bandwidth on demand, at any time on a real-time basis, through the customer's initiative to promote bandwidth-rich applications, such as grid computing, real-time digital-cinema streaming, medical and educational applications, and network storage in e-commerce.

Extreme and Local 3rd Harmonic Response of Niobium (Nb) Superconductor

Science.gov (United States)

Oripov, Bakhrom; Tai, Tamin; Anlage, Steven

Superconducting Radio Frequency (SRF) cavities are being widely used in new generation particle accelerators. These SRF cavities are based on bulk Nb. Based on the needs of the SRF community to identify defects on Nb surfaces, a novel near-field magnetic microwave microscope was successfully built using a magnetic writer from a conventional magnetic recording hard-disk drive1. This magnetic writer can create an RF magnetic field, localized and strong enough to drive Nb into the vortex state. This probe enables us to locate defects through scanning and mapping of the local electrodynamic response in the multi-GHz frequency range. Recent measurements have shown that 3rd harmonic nonlinear response is far more sensitive to variations in input power and temperature then linear response, thus we mainly study the 3rd harmonic response. Moreover, the superconductor is usually the only source for nonlinear response in our setup, thus there is less chance of having noise or background signal. Understanding the mechanism responsible for this non-linear response is important for improving the performance of SRF cavities. Besides Nb we also study various other superconductors such as MgB2 and the cuprate Bi-Sr-Ca-Cu-O (BSCCO) for potential applications in SRF cavities. This work is funded by US Department of Energy through Grant # DE-SC0012036T and CNAM.

A Methodology for Collective Evaluation and Selection of Industrial R&D Projects

OpenAIRE

Muhittin Oral; Ossama Kettani; Pascal Lang

1991-01-01

This paper proposes a methodology for evaluating and selecting R&D projects in a collective decision setting, especially useful at sectorial and national levels. It consists of two major phases: Evaluation and Selection. The evaluation process repeatedly uses mathematical programming models to determine the "relative values" of a given R&D project from the viewpoint of the other R&D projects. The selection process of R&D projects is based on these "relative values" and is done through a model...

R&D cooperation versus R&D subcontracting: empirical evidence from French survey data.

OpenAIRE

Estelle Dhont-Peltrault; Etienne Pfister

2007-01-01

This paper uses a survey of French firms active in R&D to identify the determinants of R&D outsourcing and of the ensuing trade-off between R&D subcontracting and R&D cooperation. Internal R&D expenditures increase both the probability of outsourcing and the number of R&D partners. Investment in fundamental R&D, group belonging, and the sector’s high R&D intensity positively influences the probability of R&D outsourcing but have less impact on the number of partners. R&D subcontracting is mor...

3rd International Conference on Intelligent Technologies and Engineering Systems

CERN Document Server

2016-01-01

This book includes the original, peer reviewed research from the 3rd International Conference on Intelligent Technologies and Engineering Systems (ICITES2014), held in December, 2014 at Cheng Shiu University in Kaohsiung, Taiwan. Topics covered include: Automation and robotics, fiber optics and laser technologies, network and communication systems, micro and nano technologies, and solar and power systems. This book also Explores emerging technologies and their application in a broad range of engineering disciplines Examines fiber optics and laser technologies Covers biomedical, electrical, industrial, and mechanical systems Discusses multimedia systems and applications, computer vision and image & video signal processing.

Abundant off-target edits from site-directed RNA editing can be reduced by nuclear localization of the editing enzyme.

Science.gov (United States)

Vallecillo-Viejo, Isabel C; Liscovitch-Brauer, Noa; Montiel-Gonzalez, Maria Fernanda; Eisenberg, Eli; Rosenthal, Joshua J C

2018-01-02

Site-directed RNA editing (SDRE) is a general strategy for making targeted base changes in RNA molecules. Although the approach is relatively new, several groups, including our own, have been working on its development. The basic strategy has been to couple the catalytic domain of an adenosine (A) to inosine (I) RNA editing enzyme to a guide RNA that is used for targeting. Although highly efficient on-target editing has been reported, off-target events have not been rigorously quantified. In this report we target premature termination codons (PTCs) in messages encoding both a fluorescent reporter protein and the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein transiently transfected into human epithelial cells. We demonstrate that while on-target editing is efficient, off-target editing is extensive, both within the targeted message and across the entire transcriptome of the transfected cells. By redirecting the editing enzymes from the cytoplasm to the nucleus, off-target editing is reduced without compromising the on-target editing efficiency. The addition of the E488Q mutation to the editing enzymes, a common strategy for increasing on-target editing efficiency, causes a tremendous increase in off-target editing. These results underscore the need to reduce promiscuity in current approaches to SDRE.

R&D for Collider Beauty Physics at the LHC

CERN Multimedia

2002-01-01

We propose an R&D program for the development of a Beauty trigger and innovative elements of the associated spectrometer. The program builds on the success of the recent S$\\bar{p}$pS collider run of the P238 Collaboration, in which clean signals from beam-beam interactions were observed in a large silicon strip microvertex detector running 1.5~mm from the circulating beams. A continuing successful R&D program of the type proposed could ultimately lead to a collider experiment at the LHC to study CP-violation and rare B decays. \\\\ \\\\ We request a fixed target run during late 1992 in order to demonstrate the effectiveness of a heavy flavour trigger which uses real time digital calculations on silicon strip data, implemented with a data driven processor.

Transportation Energy Data Book: Edition 23

Energy Technology Data Exchange (ETDEWEB)

Davis, S.C.

2003-10-24

The ''Transportation Energy Data Book: Edition 23'' is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the Office of Planning, Budget Formulation, and Analysis, under the Energy Efficiency and Renewable Energy (EERE) program in the Department of Energy (DOE). Designed for use as a desk-top reference, the data book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest editions of the Data Book are available to a larger audience via the Internet (www-cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2--energy; Chapter 3--highway vehicles; Chapter 4--light vehicles; Chapter 5--heavy vehicles; Chapter 6--alternative fuel vehicles; Chapter 7--fleet vehicles; Chapter 8--household vehicles; and Chapter 9--nonhighway modes; Chapter 10--transportation and the economy; Chapter 11--greenhouse gas emissions; and Chapter 12--criteria pollutant emissions. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the readers convenience.

Transportation Energy Data Book: Edition 24

Energy Technology Data Exchange (ETDEWEB)

Davis, S.C.

2005-03-08

The ''Transportation Energy Data Book: Edition 24'' is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the Office of Planning, Budget Formulation, and Analysis, under the Energy Efficiency and Renewable Energy (EERE) program in the Department of Energy (DOE). Designed for use as a desk-top reference, the data book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest editions of the Data Book are available to a larger audience via the Internet (cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2--energy; Chapter 3--highway vehicles; Chapter 4--light vehicles; Chapter 5--heavy vehicles; Chapter 6--alternative fuel vehicles; Chapter 7--fleet vehicles; Chapter 8--household vehicles; and Chapter 9--nonhighway modes; Chapter 10--transportation and the economy; Chapter 11--greenhouse gas emissions; and Chapter 12--criteria pollutant emissions. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the readers convenience.

Transportation Energy Data Book: Edition 29

Energy Technology Data Exchange (ETDEWEB)

Davis, Stacy Cagle [ORNL; Diegel, Susan W [ORNL; Boundy, Robert Gary [ORNL

2010-07-01

The Transportation Energy Data Book: Edition 29 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, Vehicle Technologies Program. Designed for use as a desk-top reference, the Data Book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest edition of the Data Book is available to a larger audience via the Internet (cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2 energy; Chapter 3 highway vehicles; Chapter 4 light vehicles; Chapter 5 heavy vehicles; Chapter 6 alternative fuel vehicles; Chapter 7 fleet vehicles; Chapter 8 household vehicles; Chapter 9 nonhighway modes; Chapter 10 transportation and the economy; Chapter 11 greenhouse gas emissions; and Chapter 12 criteria pollutant emissions. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the reader s convenience.

Transportation Energy Data Book: Edition 30

Energy Technology Data Exchange (ETDEWEB)

Davis, Stacy Cagle [ORNL; Diegel, Susan W [ORNL; Boundy, Robert Gary [ORNL

2011-07-01

The Transportation Energy Data Book: Edition 30 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, Vehicle Technologies Program. Designed for use as a desk-top reference, the Data Book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest edition of the Data Book is available to a larger audience via the Internet (cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2 energy; Chapter 3 highway vehicles; Chapter 4 light vehicles; Chapter 5 heavy vehicles; Chapter 6 alternative fuel vehicles; Chapter 7 fleet vehicles; Chapter 8 household vehicles; Chapter 9 nonhighway modes; Chapter 10 transportation and the economy; Chapter 11 greenhouse gas emissions; and Chapter 12 criteria pollutant emissions. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the reader s convenience.

Transportation Energy Data Book: Edition 31

Energy Technology Data Exchange (ETDEWEB)

Davis, Stacy Cagle [ORNL; Diegel, Susan W [ORNL; Boundy, Robert Gary [ORNL

2012-08-01

The Transportation Energy Data Book: Edition 31 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, Vehicle Technologies Program. Designed for use as a desk-top reference, the Data Book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest edition of the Data Book is available to a larger audience via the Internet (cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2 energy; Chapter 3 highway vehicles; Chapter 4 light vehicles; Chapter 5 heavy vehicles; Chapter 6 alternative fuel vehicles; Chapter 7 fleet vehicles; Chapter 8 household vehicles; Chapter 9 nonhighway modes; Chapter 10 transportation and the economy; Chapter 11 greenhouse gas emissions; and Chapter 12 criteria pollutant emissions. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the reader s convenience.

Transportation Energy Data Book: Edition 27

Energy Technology Data Exchange (ETDEWEB)

Davis, Stacy Cagle [ORNL; Diegel, Susan W [ORNL; Boundy, Robert Gary [ORNL

2008-06-01

The Transportation Energy Data Book: Edition 27 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the Office of Planning, Budget Formulation, and Analysis, under the Energy Efficiency and Renewable Energy (EERE) program in the Department of Energy (DOE). Designed for use as a desk-top reference, the data book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest editions of the Data Book are available to a larger audience via the Internet (cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2 energy; Chapter 3 highway vehicles; Chapter 4 light vehicles; Chapter 5 heavy vehicles; Chapter 6 alternative fuel vehicles; Chapter 7 fleet vehicles; Chapter 8 household vehicles; and Chapter 9 nonhighway modes; Chapter 10 transportation and the economy; Chapter 11 greenhouse gas emissions; and Chapter 12 criteria pollutant emissions. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the readers convenience.

Transportation Energy Data Book: Edition 26

Energy Technology Data Exchange (ETDEWEB)

Davis, Stacy Cagle [ORNL; Diegel, Susan W [ORNL

2007-07-01

The Transportation Energy Data Book: Edition 26 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the Office of Planning, Budget Formulation, and Analysis, under the Energy Efficiency and Renewable Energy (EERE) program in the Department of Energy (DOE). Designed for use as a desk-top reference, the data book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest editions of the Data Book are available to a larger audience via the Internet (cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2 - energy; Chapter 3 - highway vehicles; Chapter 4 - light vehicles; Chapter 5 - heavy vehicles; Chapter 6 - alternative fuel vehicles; Chapter 7 - fleet vehicles; Chapter 8 - household vehicles; and Chapter 9- nonhighway modes; Chapter 10 - transportation and the economy; Chapter 11 - greenhouse gas emissions; and Chapter 12 - criteria pollutant emissions. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the readers convenience.

Transportation Energy Data Book: Edition 25

Energy Technology Data Exchange (ETDEWEB)

Davis, Stacy Cagle [ORNL; Diegel, Susan W [ORNL

2006-06-01

The Transportation Energy Data Book: Edition 25 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the Office of Planning, Budget Formulation, and Analysis, under the Energy Efficiency and Renewable Energy (EERE) program in the Department of Energy (DOE). Designed for use as a desk-top reference, the data book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest editions of the Data Book are available to a larger audience via the Internet (cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2 - energy; Chapter 3 - highway vehicles; Chapter 4 - light vehicles; Chapter 5 - heavy vehicles; Chapter 6 - alternative fuel vehicles; Chapter 7 - fleet vehicles; Chapter 8 - household vehicles; and Chapter 9- nonhighway modes; Chapter 10 - transportation and the economy; Chapter 11 - greenhouse gas emissions; and Chapter 12 - criteria pollutant emissions. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the readers convenience.

Transportation Energy Data Book: Edition 22

Energy Technology Data Exchange (ETDEWEB)

Davis, Stacy C.; Diegel, Susan W.

2002-12-04

The Transportation Energy Data Book: Edition 22 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the Office of Planning, Budget Formulation, and Analysis, under the Energy Efficiency and Renewable Energy (EERE) program in the Department of Energy (DOE). Designed for use as a desk-top reference, the data book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest editions of the Data Book are available to a larger audience via the Internet (www.cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2 - energy; Chapter 3 - greenhouse gas emissions; Chapter 4 - criteria pollutant emissions; Chapter 5 - transportation and the economy; Chapter 6 - highway vehicles; Chapter 7 - light vehicles; Chapter 8 - heavy vehicles; Chapter 9 - alternative fuel vehicles; Chapter 10 - fleet vehicles; Chapter 11 - household vehicles; and Chapter 12- nonhighway modes. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the readers convenience.

“Patenting Bioprinting Technologies in the US and Europe– The 5th element in the 3rd dimension"

DEFF Research Database (Denmark)

Minssen, Timo; Mimler, Marc

2017-01-01

of bioprinting- inventions are being patented or would be- protectable under European and US patent laws. Rather than focusing on the highly relevant questions that 3D printing poses for patent infringement doctrines and research exemptions , this paper concentrates on the question of patentable subject matter......, “Patenting Bioprinting Technologies in the US and Europe– The 5th element in the 3rd dimension", Working Paper, forthcoming in: RM Ballardini, M Norrgård & J Partanen (red), 3D printing, Intellectual Property and Innovation – Insights from Law and Technology. Wolters Klu. Available at https...

Technical Optimization of Cross-Platform Software Development Process quality and Usability of 3rd-Party Tools

Directory of Open Access Journals (Sweden)

Yevgueny Kondratyev

2016-03-01

Full Text Available The article exposes developer's point of view on minimizing creation, upgrade, post-release problem solving time for applications and components, targeted to multiple operating systems, while keeping high end product quality and computational performance. Non-uniformity of analogous tools and components, available on different platforms, causes strong impact on developer's productivity. In part., differences in 3rd-party component interfaces, versions, quality of distinct functions, cause frequent switching developer's attention on issues not connected (in principle with the target project. While loss of development performance because of attention specifics is more subjective value, at least physical time spent on tools/components misbehavior compensation and normal tools configuring is measurable. So, the main thesis verified is whether it's possible to increase continuity of the development process by technical improvements only, and by which value. In addition, a novel experimental tool for interactive code execution is described, allowing for deep changes in the working program without its restart. Question under research: minimizing durations of programming-build-test-correct loop and small code parts runs, in part., improving the debugging workflow for the account of combining the interactive editor and the debugger.

A Novel Parallel Algorithm for Edit Distance Computation

Directory of Open Access Journals (Sweden)

Muhammad Murtaza Yousaf

2018-01-01

Full Text Available The edit distance between two sequences is the minimum number of weighted transformation-operations that are required to transform one string into the other. The weighted transformation-operations are insert, remove, and substitute. Dynamic programming solution to find edit distance exists but it becomes computationally intensive when the lengths of strings become very large. This work presents a novel parallel algorithm to solve edit distance problem of string matching. The algorithm is based on resolving dependencies in the dynamic programming solution of the problem and it is able to compute each row of edit distance table in parallel. In this way, it becomes possible to compute the complete table in min(m,n iterations for strings of size m and n whereas state-of-the-art parallel algorithm solves the problem in max(m,n iterations. The proposed algorithm also increases the amount of parallelism in each of its iteration. The algorithm is also capable of exploiting spatial locality while its implementation. Additionally, the algorithm works in a load balanced way that further improves its performance. The algorithm is implemented for multicore systems having shared memory. Implementation of the algorithm in OpenMP shows linear speedup and better execution time as compared to state-of-the-art parallel approach. Efficiency of the algorithm is also proven better in comparison to its competitor.

Starting Young: Massachusetts Birth-3rd Grade Policies That Support Children's Literacy Development

Science.gov (United States)

Cook, Shayna; Bornfreund, Laura

2015-01-01

Massachusetts is one of a handful of states that is often recognized as a leader in public education, and for good reason. The Commonwealth consistently outperforms most states on national reading and math tests and often leads the pack in education innovations. "Starting Young: Massachusetts Birth-3rd Grade Policies that Support Children's…

REDIdb 3.0: A Comprehensive Collection of RNA Editing Events in Plant Organellar Genomes.

Science.gov (United States)

Lo Giudice, Claudio; Pesole, Graziano; Picardi, Ernesto

2018-01-01

RNA editing is an important epigenetic mechanism by which genome-encoded transcripts are modified by substitutions, insertions and/or deletions. It was first discovered in kinetoplastid protozoa followed by its reporting in a wide range of organisms. In plants, RNA editing occurs mostly by cytidine (C) to uridine (U) conversion in translated regions of organelle mRNAs and tends to modify affected codons restoring evolutionary conserved aminoacid residues. RNA editing has also been described in non-protein coding regions such as group II introns and structural RNAs. Despite its impact on organellar transcriptome and proteome complexity, current primary databases still do not provide a specific field for RNA editing events. To overcome these limitations, we developed REDIdb a specialized database for RNA editing modifications in plant organelles. Hereafter we describe its third release containing more than 26,000 events in a completely novel web interface to accommodate RNA editing in its genomics, biological and evolutionary context through whole genome maps and multiple sequence alignments. REDIdb is freely available at http://srv00.recas.ba.infn.it/redidb/index.html.

REDIdb 3.0: A Comprehensive Collection of RNA Editing Events in Plant Organellar Genomes

Directory of Open Access Journals (Sweden)

Claudio Lo Giudice

2018-04-01

Full Text Available RNA editing is an important epigenetic mechanism by which genome-encoded transcripts are modified by substitutions, insertions and/or deletions. It was first discovered in kinetoplastid protozoa followed by its reporting in a wide range of organisms. In plants, RNA editing occurs mostly by cytidine (C to uridine (U conversion in translated regions of organelle mRNAs and tends to modify affected codons restoring evolutionary conserved aminoacid residues. RNA editing has also been described in non-protein coding regions such as group II introns and structural RNAs. Despite its impact on organellar transcriptome and proteome complexity, current primary databases still do not provide a specific field for RNA editing events. To overcome these limitations, we developed REDIdb a specialized database for RNA editing modifications in plant organelles. Hereafter we describe its third release containing more than 26,000 events in a completely novel web interface to accommodate RNA editing in its genomics, biological and evolutionary context through whole genome maps and multiple sequence alignments. REDIdb is freely available at http://srv00.recas.ba.infn.it/redidb/index.html

3rd Workshop on Branching Processes and their Applications

CERN Document Server

González, Miguel; Gutiérrez, Cristina; Martínez, Rodrigo; Minuesa, Carmen; Molina, Manuel; Mota, Manuel; Ramos, Alfonso; WBPA15

2016-01-01

This volume gathers papers originally presented at the 3rd Workshop on Branching Processes and their Applications (WBPA15), which was held from 7 to 10 April 2015 in Badajoz, Spain (http://branching.unex.es/wbpa15/index.htm). The papers address a broad range of theoretical and practical aspects of branching process theory. Further, they amply demonstrate that the theoretical research in this area remains vital and topical, as well as the relevance of branching concepts in the development of theoretical approaches to solving new problems in applied fields such as Epidemiology, Biology, Genetics, and, of course, Population Dynamics. The topics covered can broadly be classified into the following areas: 1. Coalescent Branching Processes 2. Branching Random Walks 3. Population Growth Models in Varying and Random Environments 4. Size/Density/Resource-Dependent Branching Models 5. Age-Dependent Branching Models 6. Special Branching Models 7. Applications in Epidemiology 8. Applications in Biology and Genetics Offer...

REDItools: high-throughput RNA editing detection made easy.

Science.gov (United States)

Picardi, Ernesto; Pesole, Graziano

2013-07-15

The reliable detection of RNA editing sites from massive sequencing data remains challenging and, although several methodologies have been proposed, no computational tools have been released to date. Here, we introduce REDItools a suite of python scripts to perform high-throughput investigation of RNA editing using next-generation sequencing data. REDItools are in python programming language and freely available at http://code.google.com/p/reditools/. ernesto.picardi@uniba.it or graziano.pesole@uniba.it Supplementary data are available at Bioinformatics online.

Small Business Innovation Research : Program Solicitation (Closing Date : May 3, 1994)

Science.gov (United States)

1994-01-01

The Small Business Innovation Research (SBIR) Program is the primary vehicle through which the federal government funds research and development (R&D) projects at small technology companies. The SBIR Program of the Department of Transportation is a r...

Advances in genome editing for improved animal breeding: A review

Directory of Open Access Journals (Sweden)

Shakil Ahmad Bhat

2017-11-01

Full Text Available Since centuries, the traits for production and disease resistance are being targeted while improving the genetic merit of domestic animals, using conventional breeding programs such as inbreeding, outbreeding, or introduction of marker-assisted selection. The arrival of new scientific concepts, such as cloning and genome engineering, has added a new and promising research dimension to the existing animal breeding programs. Development of genome editing technologies such as transcription activator-like effector nuclease, zinc finger nuclease, and clustered regularly interspaced short palindromic repeats systems begun a fresh era of genome editing, through which any change in the genome, including specific DNA sequence or indels, can be made with unprecedented precision and specificity. Furthermore, it offers an opportunity of intensification in the frequency of desirable alleles in an animal population through gene-edited individuals more rapidly than conventional breeding. The specific research is evolving swiftly with a focus on improvement of economically important animal species or their traits all of which form an important subject of this review. It also discusses the hurdles to commercialization of these techniques despite several patent applications owing to the ambiguous legal status of genome-editing methods on account of their disputed classification. Nonetheless, barring ethical concerns gene-editing entailing economically important genes offers a tremendous potential for breeding animals with desirable traits.

Efficient parallel algorithms for string editing and related problems

Science.gov (United States)

Apostolico, Alberto; Atallah, Mikhail J.; Larmore, Lawrence; Mcfaddin, H. S.

1988-01-01

The string editing problem for input strings x and y consists of transforming x into y by performing a series of weighted edit operations on x of overall minimum cost. An edit operation on x can be the deletion of a symbol from x, the insertion of a symbol in x or the substitution of a symbol x with another symbol. This problem has a well known O((absolute value of x)(absolute value of y)) time sequential solution (25). The efficient Program Requirements Analysis Methods (PRAM) parallel algorithms for the string editing problem are given. If m = ((absolute value of x),(absolute value of y)) and n = max((absolute value of x),(absolute value of y)), then the CREW bound is O (log m log n) time with O (mn/log m) processors. In all algorithms, space is O (mn).

Stable isotope geochemistry. 3. rev. and enl. ed.

International Nuclear Information System (INIS)

Hoefs, J.

1987-01-01

Stable Isotope Geochemistry is an authoritative book comprising theoretical and experimental principles; surveying important fractionation mechanisms affecting the most important elements; discussing the natural variations of geologically important reservoirs. This updated 3rd edition, with a completely rewritten and extended main part, contains two new chapters on stable isotope composition of mantle material and on changes of the ocean during the geological past. (orig.)

Do 2nd and 3rd Grade Teachers' Linguistic Knowledge and Instructional Practices Predict Spelling Gains in Weaker Spellers?

Science.gov (United States)

Puliatte, Alison; Ehri, Linnea C.

2018-01-01

The relationship between 2nd and 3rd grade teachers' linguistic knowledge and spelling instructional practices and their students' spelling gains from fall to spring was examined. Second grade (N = 16) and 3rd grade (N = 16) teachers were administered an instructional practices survey and a linguistic knowledge test. Total scores on the two…

Stages of Geoinformation Evolution Related to the Territories Described in the Bible - from the 3Rd Millennium B.C. to Modern Times

Science.gov (United States)

Linsenbarth, Adam

2012-09-01

The paper presents consecutive stages of the evolution of geoinformation related to the territories of the events described in the Bible. Two geoinformation sources are presented: the Bible and non-Bible sources. In the Bible there is much, often some highly detailed information regarding terrain topography. The oldest non-Bible sources are incorporated in the ancient documents, which were discovered in Egypt and Mesopotamia. Some of them are related to the 3rd millen- nium B.C. The further stages are related to the onomasticons and itineraries written by travellers and pilgrims to the Holy Land. The most famous onomasticons include: onomasticons prepared by bishop Eusebius from Caesarea and those pre- pared by St. Jerome. One of the oldest maps of Palestine's territory is the so-called mosaic map of Madaba dated to 565. In the 15th century several Bible maps were edited. The most rapid evolution occurred in the 16th and 17* centuries, when the world famous cartographers such as Mercator and Ortelius edited several maps of Palestine's territory. Cartographers from several European countries edited more than 6,000 maps presenting the Biblical territories and Biblical events. Modem maps, based on detailed topographical surveys, were edited m the second half of the 19* and 20th centuries. W artykule przedstawiono kolejne etapy rozwoju geoinformacji dotyczącej terenówr biblijnych. Omówiono dwa źródła informacji, a mianowicie geoinformacje biblijne i pozabiblijne. W tekstach biblijnych można znaleźć wiele, często bardzo detalicznych informacji topograficznych. Najstarsze źródła pozabiblijne, to starożytne dokumenty odnalezione na terenach Egiptu i Mezopotamii. Niektóre z nich pochodzą z trzeciego milenium przed Chr. Kolejnym etapem geoinformacji były onomastikony oraz dzienniki podróży pisane przez podróżników i pielgrzymów do Ziemi Świętej. Do najbardziej znanych należy onomastikon sporządzony przez biskupa Euzebiusza z Cezarei oraz

R&D for a single-layer Nb$_{3}$Sn common coil dipole using the react-and-wind fabrication technique

CERN Document Server

Ambrosio, G; Barzi, E; Bauer, P; Chichili, D R; Ewald, K D; Fehér, S; Imbasciati, L; Kashikhin, V V; Limon, P J; Litvinenko, L; Novitski, I; Rey, J M; Scanlan, R M; Yadav, S; Yamada, R; Zlobin, A V

2002-01-01

A dipole magnet based on the common coil design, using prereacted Nb /sub 3/Sn superconductor, is under development at Fermilab, for a future Very Large Hadron Collider. This magnet has some innovative design and technological features such as single layer coils, a 22 mm wide 60-strand Rutherford type cable and stainless steel collars reinforced by horizontal bridges inserted between coil blocks. Both left and right coils are wound simultaneously into the collar structure and then impregnated with epoxy. In order to optimize the design and fabrication techniques an R&D program is underway. The production of cables with the required characteristics was shown possible. Collar laminations were produced, assembled and tested in order to check the effectiveness of the bridges and the validity of the mechanical design. A mechanical model consisting in a 165 mm long section of the magnet straight section was assembled and tested. This paper summarizes the status of the program, and reports the results of fabrica...

Editorial: 3rd Special Issue on behavior change, health, and health disparities.

Science.gov (United States)

Higgins, Stephen T

2016-11-01

This Special Issue of Preventive Medicine (PM) is the 3rd that we have organized on behavior change, health, and health disparities. This is a topic of critical importance to improving U.S. population health. There is broad scientific consensus that personal behaviors such as cigarette smoking, other substance abuse, and physical inactivity/obesity are among the most important modifiable causes of chronic disease and its adverse impacts on population health. Hence, effectively promoting health-related behavior change needs to be a key component of health care research and policy. There is also broad recognition that while these problems extend throughout the population, they disproportionately impact economically disadvantaged populations and other vulnerable populations and represent a major contributor to health disparities. Thus, behavior change represents an essential step in curtailing health disparities, which receives special attention in this 3rd Special Issue. We also devote considerable space to the longstanding challenges of reducing cigarette smoking and use of other tobacco and nicotine delivery products in vulnerable populations, obesity, and for the first time food insecurity. Across each of these topics we include contributions from highly accomplished policymakers and scientists to acquaint readers with recent accomplishments as well as remaining knowledge gaps and challenges. Copyright © 2016 Elsevier Inc. All rights reserved.

Residential and Light Commercial HVAC. Teacher Edition and Student Edition. Second Edition.

Science.gov (United States)

Stephenson, David

This package contains teacher and student editions of a residential and light commercial heating, ventilation, and air conditioning (HVAC) course of study. The teacher edition contains information on the following: using the publication; national competencies; competency profile; related academic and workplace skills list; tools, equipment, and…

3rd Workshop on "Combinations of Intelligent Methods and Applications"

CERN Document Server

Palade, Vasile

2013-01-01

The combination of different intelligent methods is a very active research area in Artificial Intelligence (AI). The aim is to create integrated or hybrid methods that benefit from each of their components.  The 3rd Workshop on “Combinations of Intelligent Methods and Applications” (CIMA 2012) was intended to become a forum for exchanging experience and ideas among researchers and practitioners who are dealing with combining intelligent methods either based on first principles or in the context of specific applications. CIMA 2012 was held in conjunction with the 22nd European Conference on Artificial Intelligence (ECAI 2012).This volume includes revised versions of the papers presented at CIMA 2012.  .

estec2007 - 3rd European solar thermal energy conference. Proceedings

Energy Technology Data Exchange (ETDEWEB)

NONE

2007-12-14

The sessions of the 'estec2007 - 3{sup rd} European Solar Thermal Energy Conference held in Freiburg, Germany have the following titles: The solar thermal sector at a turning point; Cooling and Process Heat, Country reports Europe; Standards and Certification; Country reports outside Europe; Awareness raising and marketing; Domestic hot water and space heating; Domestic hot water and space heating; Quality Assurance and Solar Thermal Energy Service Companies; Collectors and other key technical issues; Policy - Financial incentives; Country Reports; Marketing and Awareness Raising; Quality Assurance Measures/Monistoring; Standards and Certification; Collectors; Domestic Hot Water and Space Heating; Industrial Process Heat; Storage; Solar Cooling. (AKF)

estec2007 - 3rd European solar thermal energy conference. Proceedings

Energy Technology Data Exchange (ETDEWEB)

NONE

2007-12-14

The sessions of the 'estec2007 - 3{sup rd} European Solar Thermal Energy Conference held in Freiburg, Germany have the following titles: The solar thermal sector at a turning point; Cooling and Process Heat, Country reports Europe; Standards and Certification; Country reports outside Europe; Awareness raising and marketing; Domestic hot water and space heating; Domestic hot water and space heating; Quality Assurance and Solar Thermal Energy Service Companies; Collectors and other key technical issues; Policy - Financial incentives; Country Reports; Marketing and Awareness Raising; Quality Assurance Measures/Monistoring; Standards and Certification; Collectors; Domestic Hot Water and Space Heating; Industrial Process Heat; Storage; Solar Cooling. (AKF)

CERN openlab: Engaging industry for innovation in the LHC Run 3-4 R&D programme

Science.gov (United States)

Girone, M.; Purcell, A.; Di Meglio, A.; Rademakers, F.; Gunne, K.; Pachou, M.; Pavlou, S.

2017-10-01

LHC Run3 and Run4 represent an unprecedented challenge for HEP computing in terms of both data volume and complexity. New approaches are needed for how data is collected and filtered, processed, moved, stored and analysed if these challenges are to be met with a realistic budget. To develop innovative techniques we are fostering relationships with industry leaders. CERN openlab is a unique resource for public-private partnership between CERN and leading Information Communication and Technology (ICT) companies. Its mission is to accelerate the development of cutting-edge solutions to be used by the worldwide HEP community. In 2015, CERN openlab started its phase V with a strong focus on tackling the upcoming LHC challenges. Several R&D programs are ongoing in the areas of data acquisition, networks and connectivity, data storage architectures, computing provisioning, computing platforms and code optimisation and data analytics. This paper gives an overview of the various innovative technologies that are currently being explored by CERN openlab V and discusses the long-term strategies that are pursued by the LHC communities with the help of industry in closing the technological gap in processing and storage needs expected in Run3 and Run4.

Business planning for scientists and engineers[3rd edition]; TOPICAL

International Nuclear Information System (INIS)

Servo, Jenny C.

1999-01-01

This combination text/workbook is intended for use by scientists or engineers actively engaged in developing a product or technology to commercial production. The 'how' of planning is a central theme with special emphasis on development of operational plans and strategic thinking

Growth and mineral nutrition of field crops 3rd Edition

Science.gov (United States)

Green revolution technology of last century led to increased production. The green revolution, however, did not link farming system sustainability to food system sustainability as a whole. In recent years the rate of food-grain production has been lower than the rate of population growth. This will ...

3rd International Workshop on Turbulent Spray Combustion

CERN Document Server

Gutheil, Eva

2014-01-01

This book reflects the results of the 2nd and 3rd International Workshops on Turbulent Spray Combustion. The focus is on progress in experiments and numerical simulations for two-phase flows, with emphasis on spray combustion. Knowledge of the dominant phenomena and their interactions allows development of predictive models and their use in combustor and gas turbine design. Experts and young researchers present the state-of-the-art results, report on the latest developments and exchange ideas in the areas of experiments, modelling and simulation of reactive multiphase flows. The first chapter reflects on flame structure, auto-ignition and atomization with reference to well-characterized burners, to be implemented by modellers with relative ease. The second chapter presents an overview of first simulation results on target test cases, developed at the occasion of the 1st International Workshop on Turbulent Spray Combustion. In the third chapter, evaporation rate modelling aspects are covered, while the fourth ...

Recent developments at 3rd generation storage ring light sources (3/4)

CERN Multimedia

CERN. Geneva

2009-01-01

Over the last decade, many 3rd generation storage ring light sources have been built and put into operation. Progressively, significant improvements have been brought to the machine performances and experiences developed at the first facilities have benefited to the most recently built ones. Most of the recent facilities are now featuring small emittances, high current together with high position stability. The small sizes of the electron beam at the source points impose achieving position stabilities in the sub micron range. The technology to build the insertion devices that produce the photon beams has reached a very mature state and enables 3 GeV medium energy /medium size machines to produce high brilliance beams up to the hard X-Ray range (10 - 30 keV). The designing of the optical set-up of a beamline includes now the choice of the best suited undulator. All these facilities are operated as “photon factories” and deliver their beams to many beamlines over several thousands hours per year. Some re...

Production of Purified CasRNPs for Efficacious Genome Editing.

Science.gov (United States)

Lingeman, Emily; Jeans, Chris; Corn, Jacob E

2017-10-02

CRISPR-Cas systems have been harnessed as modular genome editing reagents for functional genomics and show promise to cure genetic diseases. Directed by a guide RNA, a Cas effector introduces a double stranded break in DNA and host cell DNA repair leads to the introduction of errors (e.g., to knockout a gene) or a programmed change. Introduction of a Cas effector and guide RNA as a purified Cas ribonucleoprotein complex (CasRNP) has recently emerged as a powerful approach to alter cell types and organisms. Not only does CasRNP editing exhibit increased efficacy and specificity, it avoids optimization and iteration of species-specific factors such as codon usage, promoters, and terminators. CasRNP editing has been rapidly adopted for research use in many contexts and is quickly becoming a popular method to edit primary cells for therapeutic application. This article describes how to make a Cas9 RNP and outlines its use for gene editing in human cells. © 2017 by John Wiley & Sons, Inc. Copyright © 2017 John Wiley & Sons, Inc.

Introduction to Energy - 2nd Edition

Science.gov (United States)

Cassedy, Edward S.; Grossman, Peter Z.

1998-12-01

Energy issues such as pollution, resource depletion, global warming, nuclear power and waste are problems that demand timely solutions. This book provides a critical examination of the resources, market forces, and social impacts of modern energy production. The book addresses the dilemmas that have arisen due to society's crucial dependence on energy, particularly fossil fuels, and explores the available alternative energy producing technologies. The second edition has increased emphasis on those issues at the forefront of the current energy debate: energy sustainability, climate change, and the radical restructuring of the power industry due to de-regulation. Assuming no prior technical expertise and avoiding complex mathematical formulation, it is directed at a broad readership. The second edition will follow the first in proving especially useful as a textbook for undergraduate programs in Science, Technology and Society (STS), and as a supplementary text in a variety of courses which touch upon energy studies, including environmental and technology policy, environmental, mineral and business law, energy and resource economics. Fully updated second edition of successful first edition that was adopted on Science, Technology and Society courses Provides a critical examination of all aspects of modern energy production for non-technical readers For a broad readership from a variety of backgrounds

3rd Symposium on Space Optical Instruments and Applications

CERN Document Server

Zhang, Guangjun

2017-01-01

This volume contains selected and expanded contributions presented at the 3rd Symposium on Space Optical Instruments and Applications in Beijing, China June 28 – 29, 2016. This conference series is organised by the Sino-Holland Space Optical Instruments Laboratory, a cooperation platform between China and the Netherlands. The symposium focused on key technological problems of optical instruments and their applications in a space context. It covered the latest developments, experiments and results regarding theory, instrumentation and applications in space optics. The book is split across five topical sections. The first section covers space optical remote sensing system design, the second advanced optical system design, the third remote sensor calibration and measurement. Remote sensing data processing and information extraction is then presented, followed by a final section on remote sensing data applications. .

3rd International Conference on Nanotechnologies and Biomedical Engineering

CERN Document Server

Tiginyanu, Ion

2016-01-01

This volume presents the proceedings of the 3rd International Conference on Nanotechnologies and Biomedical Engineering which was held on September 23-26, 2015 in Chisinau, Republic of Moldova. ICNBME-2015 continues the series of International Conferences in the field of nanotechnologies and biomedical engineering. It aims at bringing together scientists and engineers dealing with fundamental and applied research for reporting on the latest theoretical developments and applications involved in the fields. Topics include Nanotechnologies and nanomaterials Plasmonics and metamaterials Bio-micro/nano technologies Biomaterials Biosensors and sensors systems Biomedical instrumentation Biomedical signal processing Biomedical imaging and image processing Molecular, cellular and tissue engineering Clinical engineering, health technology management and assessment; Health informatics, e-health and telemedicine Biomedical engineering education Nuclear and radiation safety and security Innovations and technology transfer...

Human Germline Genome Editing.

Science.gov (United States)

Ormond, Kelly E; Mortlock, Douglas P; Scholes, Derek T; Bombard, Yvonne; Brody, Lawrence C; Faucett, W Andrew; Garrison, Nanibaa' A; Hercher, Laura; Isasi, Rosario; Middleton, Anna; Musunuru, Kiran; Shriner, Daniel; Virani, Alice; Young, Caroline E

2017-08-03

With CRISPR/Cas9 and other genome-editing technologies, successful somatic and germline genome editing are becoming feasible. To respond, an American Society of Human Genetics (ASHG) workgroup developed this position statement, which was approved by the ASHG Board in March 2017. The workgroup included representatives from the UK Association of Genetic Nurses and Counsellors, Canadian Association of Genetic Counsellors, International Genetic Epidemiology Society, and US National Society of Genetic Counselors. These groups, as well as the American Society for Reproductive Medicine, Asia Pacific Society of Human Genetics, British Society for Genetic Medicine, Human Genetics Society of Australasia, Professional Society of Genetic Counselors in Asia, and Southern African Society for Human Genetics, endorsed the final statement. The statement includes the following positions. (1) At this time, given the nature and number of unanswered scientific, ethical, and policy questions, it is inappropriate to perform germline gene editing that culminates in human pregnancy. (2) Currently, there is no reason to prohibit in vitro germline genome editing on human embryos and gametes, with appropriate oversight and consent from donors, to facilitate research on the possible future clinical applications of gene editing. There should be no prohibition on making public funds available to support this research. (3) Future clinical application of human germline genome editing should not proceed unless, at a minimum, there is (a) a compelling medical rationale, (b) an evidence base that supports its clinical use, (c) an ethical justification, and (d) a transparent public process to solicit and incorporate stakeholder input. Copyright © 2017 American Society of Human Genetics. All rights reserved.

Canonical A-to-I and C-to-U RNA editing is enriched at 3'UTRs and microRNA target sites in multiple mouse tissues.

Directory of Open Access Journals (Sweden)

Tongjun Gu

Full Text Available RNA editing is a process that modifies RNA nucleotides and changes the efficiency and fidelity of the central dogma. Enzymes that catalyze RNA editing are required for life, and defects in RNA editing are associated with many diseases. Recent advances in sequencing have enabled the genome-wide identification of RNA editing sites in mammalian transcriptomes. Here, we demonstrate that canonical RNA editing (A-to-I and C-to-U occurs in liver, white adipose, and bone tissues of the laboratory mouse, and we show that apparent non-canonical editing (all other possible base substitutions is an artifact of current high-throughput sequencing technology. Further, we report that high-confidence canonical RNA editing sites can cause non-synonymous amino acid changes and are significantly enriched in 3' UTRs, specifically at microRNA target sites, suggesting both regulatory and functional consequences for RNA editing.

Mediated Plastid RNA Editing in Plant Immunity

Science.gov (United States)

García-Andrade, Javier; Ramírez, Vicente; López, Ana; Vera, Pablo

2013-01-01

Plant regulatory circuits coordinating nuclear and plastid gene expression have evolved in response to external stimuli. RNA editing is one of such control mechanisms. We determined the Arabidopsis nuclear-encoded homeodomain-containing protein OCP3 is incorporated into the chloroplast, and contributes to control over the extent of ndhB transcript editing. ndhB encodes the B subunit of the chloroplast NADH dehydrogenase-like complex (NDH) involved in cyclic electron flow (CEF) around photosystem I. In ocp3 mutant strains, ndhB editing efficiency decays, CEF is impaired and disease resistance to fungal pathogens substantially enhanced, a process recapitulated in plants defective in editing plastid RNAs encoding NDH complex subunits due to mutations in previously described nuclear-encoded pentatricopeptide-related proteins (i.e. CRR21, CRR2). Furthermore, we observed that following a pathogenic challenge, wild type plants respond with editing inhibition of ndhB transcript. In parallel, rapid destabilization of the plastidial NDH complex is also observed in the plant following perception of a pathogenic cue. Therefore, NDH complex activity and plant immunity appear as interlinked processes. PMID:24204264

Prospective testing of ICHD-3 beta diagnostic criteria for migraine with aura and migraine with typical aura in patients with transient ischemic attacks

DEFF Research Database (Denmark)

Lebedeva, Elena R; Gurary, Natalia M; Gilev, Denis V

2018-01-01

Introduction The International Classification of Headache Disorders 3rd edition beta (ICHD-3 beta) gave alternative diagnostic criteria for 1.2 migraine with aura (MA) and 1.2.1 migraine with typical aura (MTA) in the appendix. The latter were presumed to better differentiate transient ischemic...

Status and Update of the RaDIATE Collaboration R&D Program

Energy Technology Data Exchange (ETDEWEB)

Ammigan, K. [Fermilab; Hurh, P. [Fermilab

2017-07-01

The Radiation Damage In Accelerator Target Environments (RaDIATE) collaboration was founded in 2012 and currently consists of over 50 participants and 11 institutions globally. Due to the increasing power of future proton accelerator sources in target facilities, there is a critical need to further understand the physical and thermo-mechanical radiation response of target facility materials. Thus, the primary objective of the RaDIATE collaboration is to draw on existing expertise in the nuclear materials and accelerator targets fields to generate new and useful materials data for application within the accelerator and fission/fusion communities. Current research activities of the collaboration include post irradiation examination (PIE) of decommissioned components from existing beamlines such as the NuMI beryllium beam window and graphite NT-02 target material. PIE of these components includes advanced microstructural analyses (SEM/TEM, EBSD, EDS) and micro-mechanics technique such as nano-indentation, to help characterize any microstructural radiation damage incurred during operation. New irradiation campaigns of various candidate materials at both low and high energy beam facilities are also being pursued. Beryllium helium implantation studies at the University of Surrey as well as high energy proton irradiation of various materials at Brookhaven National Laboratory’s BLIP facility have been initiated. The program also extends to beam-induced thermal shock experiments using high intensity beam pulses at CERN’s HiRadMat facility, followed by advanced PIE activities to evaluate thermal shock resistance of the materials. Preliminary results from ongoing research activities, as well as the future plans of the RaDIATE collaboration R&D program will be discussed.

Status of R&D activity for ITER ICRF power source system

International Nuclear Information System (INIS)

Mukherjee, Aparajita; Trivedi, Rajesh; Singh, Raghuraj; Rajnish, Kumar; Machchhar, Harsha; Ajesh, P.; Suthar, Gajendra; Soni, Dipal; Patel, Manoj; Mohan, Kartik; Hari, J.V.S.; Anand, Rohit; Verma, Sriprakash; Agarwal, Rohit; Jha, Akhil; Kazarian, Fabienne; Beaumont, Bertrand

2015-01-01

Highlights: • R&D program to establish high power RF technology for ITER ICRF source is described. • R&D RF source is being developed using Diacrode & Tetrode technologies. • Test rig (3 MW/3600 s/35–65 MHz) simulating plasma load is developed. - Abstract: India is in-charge for the procurement of ITER Ion Cyclotron Resonance Frequency (ICRF) sources (1 Prototype + 8 series units) along with auxiliary power supplies and Local Control Unit. As there is no unique amplifier chain able to meet the output power specifications as per ITER requirement (2.5 MW per source at 35–65 MHz/CW/VSWR 2.0), two parallel three-stage amplifier chains along with a combiner circuit on the output side is considered. This kind of RF source will be unique in terms of its stringent specifications and building a first of its kind is always a challenge. An R&D phase has been initiated for establishing the technology considering single amplifier chain experimentation (1.5 MW/35–65 MHz/3600 s/VSWR 2.0) prior to Prototype and series production. This paper presents the status of R&D activity to resolve technological challenges involved and various infrastructures developed at ITER-India lab to support such operation.

Status of R&D activity for ITER ICRF power source system

Energy Technology Data Exchange (ETDEWEB)

Mukherjee, Aparajita, E-mail: aparajita.mukherjee@iter-india.org [ITER-India, Institute for Plasma Research, Bhat, Gandhinagar–382428 (India); Trivedi, Rajesh; Singh, Raghuraj; Rajnish, Kumar; Machchhar, Harsha; Ajesh, P.; Suthar, Gajendra; Soni, Dipal; Patel, Manoj; Mohan, Kartik; Hari, J.V.S.; Anand, Rohit; Verma, Sriprakash; Agarwal, Rohit; Jha, Akhil [ITER-India, Institute for Plasma Research, Bhat, Gandhinagar–382428 (India); Kazarian, Fabienne; Beaumont, Bertrand [ITER Organization, CS 90 046, 13067 Sain-Paul-Les-Durance (France)

2015-10-15

Highlights: • R&D program to establish high power RF technology for ITER ICRF source is described. • R&D RF source is being developed using Diacrode & Tetrode technologies. • Test rig (3 MW/3600 s/35–65 MHz) simulating plasma load is developed. - Abstract: India is in-charge for the procurement of ITER Ion Cyclotron Resonance Frequency (ICRF) sources (1 Prototype + 8 series units) along with auxiliary power supplies and Local Control Unit. As there is no unique amplifier chain able to meet the output power specifications as per ITER requirement (2.5 MW per source at 35–65 MHz/CW/VSWR 2.0), two parallel three-stage amplifier chains along with a combiner circuit on the output side is considered. This kind of RF source will be unique in terms of its stringent specifications and building a first of its kind is always a challenge. An R&D phase has been initiated for establishing the technology considering single amplifier chain experimentation (1.5 MW/35–65 MHz/3600 s/VSWR 2.0) prior to Prototype and series production. This paper presents the status of R&D activity to resolve technological challenges involved and various infrastructures developed at ITER-India lab to support such operation.

Clinical neuroanatomy and diagnostic imaging and evaluation of the brain. MRI and CT atlas. 3. new rev. and enl. ed.

International Nuclear Information System (INIS)

Kretschmann, H.J.; Weinrich, W.

2003-01-01

New features of this 3rd German edition are: - Number of the MR and CT images almost doubled, all pictures now in large format, displaying much more brain structures. - New knowledge and insight incorporated in the text and pictures. (orig./CB) [de

Energy technology R&D portfolio management: Modeling uncertain returns and market diffusion

International Nuclear Information System (INIS)

Bistline, John E.

2016-01-01

Highlights: • Analyzes energy R&D decisions with uncertainty in research outcomes and markets. • R&D is shown to be more valuable in second-best planning and policy environments. • Deterministic R&D approaches likely undervalue the optionality of technologies. - Abstract: The allocation of research and development (R&D) funds across a portfolio of programs must simultaneously consider uncertainty from research outcomes and from market acceptance of the resulting technologies. We introduce a stochastic R&D portfolio management framework for addressing both sources of uncertainty and present numerical results for energy technology R&D strategy under uncertainties in climate policy and natural gas prices. Numerical experiments indicate that R&D may be more valuable in second-best planning environments where decision-makers use expected-value approaches, and recourse investments occur after R&D has reduced costs. We also find that deterministic R&D valuation approaches likely overestimate the expected value of R&D success but undervalue the optionality and hedging potential of technologies relative to sequential decision-making approaches under uncertainty. The results also highlight the role of R&D in second-best policy environments.

Scientific writing and editing: a new role for the library.

Science.gov (United States)

Stephens, P A; Campbell, J M

1995-10-01

Traditional library instruction programs teach scientists how to find and manage information, but not how to report their research findings effectively. Since 1990, the William H. Welch Medical Library has sponsored classes on scientific writing and, since 1991, has offered a fee-based editing service for affiliates of the Johns Hopkins Medical Institutions. These programs were designed to fill an educational gap: Although formal instruction was offered to support other phases of the scientific communication process, the medical institutions had no central resource designed to help scientists develop and improve their writing skills. The establishment of such a resource at Welch has been well received by the community. Attendance at classes has grown steadily, and in 1993 a credit course on biomedical writing was added to the curriculum. The editing service, introduced in late 1991, has generated more requests for assistance than can be handled by the library's editor. This service not only extends the library's educational outreach but also generates a revenue stream. The Welch program in scientific writing and editing, or elements of it, could provide a model for other academic medical libraries interested in moving in this new direction.

Lead-based Fast Reactor Development Plan and R&D Status in China

International Nuclear Information System (INIS)

Wu Yican

2013-01-01

• Lead-based fast reactors have good potential for waste transmutation, fuel breeding and energy production, which has been selected by CAS as the advanced reactor development emphasis with the support of ADS program and MFE program. Sharing of technologies R&D is possible among GIF/ADS/Fusion. • The concepts and test strategy of series China lead-based fast reactors (CLEAR) have been developed. The preliminary engineering design and safety analysis of CLEAR-I are underway. • Technology R&D on CLEAR with series lead alloy loops and accelerator-based neutron generator have been constructed or under construction. • CLEAR series reactor design and construction have big challenges, widely international cooperation on reactor design and technology R&D is welcome

Deliberation of Post 3.11 Fast Reactor R&D Strategy in Japan

International Nuclear Information System (INIS)

Kondo, Shunsuke

2013-01-01

• New nuclear energy strategy is still in the process of deliberation in Japan. Though many of idled plants will be restarted after renovation of their safety features in accordance with new safety rules set by the NRA, the contribution of nuclear power in Japan will probably not return to the level before 3.11. • Japan is in the process of reviewing its strategy for SFR R&D with a view to making it compatible with the new situation to be realized under new safety regulation as well as new energy strategy to be formulated within a year. • It is contemplated that major emphasis of the SFR R&D should be on a) the completion and use of MONJU, b) FR safety and c) waste minimization, not to mention the making effective use of our knowledge basis and research and engineering capabilities cultivated through the FaCT project in the development of sustainable nuclear energy systems worldwide for future generations of mankind. • Promotion of international cooperation should be an essential ingredient of the strategy

Transforming CyberSecurity R&D within the Department of Energy: Getting Ahead of The Threat

Energy Technology Data Exchange (ETDEWEB)

Frincke, Deborah A.; Catlett, Charlie; Siebenlist, Frank; Strelitz, Richard; Talbot, Ed; Worley, Brian

2008-01-01

This report outlines a preliminary response from DOE researchers to the following three questions: a) what are the key priorities w.r.t. cybersecurity R&D over the next decade? b) what would we recommend, in terms of a program, to address those priorities c) how would a DOE Office of Science program in this area complement other cybersecurity R&D initiatives such as NSF's or other agency programs?

Developments in Processing by Severe Plastic Deformation at the 3rd Pan American Materials Congress

Science.gov (United States)

Figueiredo, Roberto B.; Kawasaki, Megumi; Langdon, Terence G.

2017-10-01

The 3rd Pan American Materials Congress in San Diego, California, February 26-March 2, 2017, provided an opportunity to bring together many participants working in the field of severe plastic deformation. This article provides a brief review of these activities.

A note on duplication of R&D and R&D subsidies

OpenAIRE

Sami Dakhlia; Akram Temimi; Flavio Menezes

2004-01-01

We show that the presumed incompatibility of uncoordinated R&D and competition is not fundamental, but hinges on the nature of R&D spillovers. As a consequence, R&D subsidies may be more effective than previously thought.

R&D Proposal RD51 Extension Beyond 2018

CERN Document Server

Dalla Torre, S; Ropelewski, L; Titov, M

2018-01-01

The RD51 Collaboration, in charge of the development and dissemination of MicroPattern Gaseous Detectors (MPGD) since 2008, proposes to extend its ac-tivity, after 2018, for a further five-year term. Since the RD51 initial years, the community of MPGD developers and users has grown considerably. It is reflected by the many MPGD-based applications in high energy and nuclear physics experi-ments as well as in other basic and applied-research fields. They rely on the parallel progress of detector concepts and associated technologies. The cultural, infrastruc-ture and networking support offered by RD51 has been essential in this process. The rich portfolio of MPGD projects, under constant expansion, is accompanied by novel ideas on further developments and applications. The proposed next term of RD51 activities aims at bringing a number of de-tector concepts to maturity, initiating new projects and continuing the support to the community. Among leading proposed projects are ultrafast, high-rate MPGDs; discharg...

Report from the 3rd Workshop on Extremely Large Databases

Directory of Open Access Journals (Sweden)

Jacek Becla

2010-02-01

Full Text Available Academic and industrial users are increasingly facing the challenge of petabytes of data, but managing and analyzing such large data sets still remains a daunting task. Both the database and the map/reduce communities worldwide are working on addressing these issues. The 3rdExtremely Large Databases workshop was organized to examine the needs of scientific communities beginning to face these issues, to reach out to European communities working on extremely large scale data challenges, and to brainstorm possible solutions. The science benchmark that emerged from the 2nd workshop in this series was also debated. This paper is the final report of the discussions and activities at this workshop.

DOE/OE Load as a Resource R&D Overview

Energy Technology Data Exchange (ETDEWEB)

Ton, Dan T. [U.S. Dept. of Energy, Washington, DC (United States)

2011-10-25

DOE R&D and OE’s PSA and ISER programs support OE’s mission to modernize electric grid, enhance energy infrastructure security and reliability, and facilitate recovery from energy supply disruptions.

GenomeVx: simple web-based creation of editable circular chromosome maps.

Science.gov (United States)

Conant, Gavin C; Wolfe, Kenneth H

2008-03-15

We describe GenomeVx, a web-based tool for making editable, publication-quality, maps of mitochondrial and chloroplast genomes and of large plasmids. These maps show the location of genes and chromosomal features as well as a position scale. The program takes as input either raw feature positions or GenBank records. In the latter case, features are automatically extracted and colored, an example of which is given. Output is in the Adobe Portable Document Format (PDF) and can be edited by programs such as Adobe Illustrator. GenomeVx is available at http://wolfe.gen.tcd.ie/GenomeVx

R&D Nuggets

Science.gov (United States)

RSS Archive Videos XML DOE R&D Accomplishments DOE R&D Accomplishments searchQuery × Find searchQuery x Find DOE R&D Acccomplishments Navigation dropdown arrow The Basics dropdown arrow Home About &D Nuggets Database dropdown arrow Search Tag Cloud Browse Reports Database Help Finding Aids

Outsourcing R&D

DEFF Research Database (Denmark)

Hsuan, Juliana; Mahnke, Volker

2011-01-01

Outsourcing R&D is an increasingly explored corporate practice. Extant research advanced our initial understanding of its increasing importance and benefits. While the associated literature has blossomed, the enthusiasm of R&D managers is tenured by an increasing realization of the possible......&D, suggest a simple, yet integrative model on the relation between outsourcing R&D and performance, and offer a research agenda that is instrumental in guiding companies’ process-management and design strategies when seeking to benefit from the outsourcing of R&D....

3rd International Symposium on Big Data and Cloud Computing Challenges

CERN Document Server

Neelanarayanan, V

2016-01-01

This proceedings volume contains selected papers that were presented in the 3rd International Symposium on Big data and Cloud Computing Challenges, 2016 held at VIT University, India on March 10 and 11. New research issues, challenges and opportunities shaping the future agenda in the field of Big Data and Cloud Computing are identified and presented throughout the book, which is intended for researchers, scholars, students, software developers and practitioners working at the forefront in their field. This book acts as a platform for exchanging ideas, setting questions for discussion, and sharing the experience in Big Data and Cloud Computing domain.

Proceedings of the 3rd NINS symposium on engineering and technology

International Nuclear Information System (INIS)

2008-10-01

The 3rd NINS Symposium on Engineering and Technology was held on 24-25, July 2008 at National Institute for Fusion Science (NIFS), organized by Department of Engineering and Technical Services, NIFS. This Symposium is continuation of an annual series. The 1st one was held on 25-26 July, 2006 organized by National Astronomical Observatory of Japan. The 2nd one was held on 25-26 June, 2007 organized by Institute for Molecular Science. This proceedings is a compilation of papers presented at the symposium. 49 participants from 5 institutes of NINS attended this symposium and 23 papers were presented. (author)

Applicability of the Rivermead Behavioural Memory Test - Third Edition (RBMT-3) in Korsakoff's syndrome and chronic alcoholics

NARCIS (Netherlands)

Wester, A.J.; Herten, J.C. van; Egger, J.I.; Kessels, R.P.C.

2013-01-01

PURPOSE: To examine the applicability of the newly developed Rivermead Behavioural Memory Test - Third Edition (RBMT-3) as an ecologically-valid memory test in patients with alcohol-related cognitive disorders. PATIENTS AND METHODS: An authorized Dutch translation of the RBMT-3 was developed,

The levels of edit. [technical writing in science

Science.gov (United States)

Vanburen, R.; Buehler, M. F.; Wallenbrock, D. (Editor)

1976-01-01

The editorial process is analyzed, and five levels of edit are identified. These levels represent cumulative combinations of nine types of edit: (1) coordination, (2) policy, (3) integrity, (4) screening, (5) copy clarification, (6) Mechanical Style, (7) Language, and (9) substantive. The levels and types of edit, although developed for specific use with external reports at the Jet Propulsion Laboratory, cover the general range of technical editing, especially as it applies to an in-house technical publications organization. Each type of edit is set forth in terms of groups of actions to be performed by the editor. The edit-level concept has enhanced understanding and communication among editors, authors, and publications managers concerning the specific editorial work to be done on each manuscript. It has also proved useful as a management tool for estimating and monitoring cost.

Applicability of the Rivermead Behavioural Memory Test - Third Edition (RBMT-3) in Korsakoff's syndrome and chronic alcoholics

NARCIS (Netherlands)

Wester, A.J.; Herten, J.C. van; Egger, J.I.M.; Kessels, R.P.C.

2013-01-01

Purpose: To examine the applicability of the newly developed Rivermead Behavioural Memory Test – Third Edition (RBMT-3) as an ecologically-valid memory test in patients with alcohol-related cognitive disorders. Patients and methods: An authorized Dutch translation of the RBMT-3 was developed,

International R&D Spillovers and Marginal Social Returns on R&D

NARCIS (Netherlands)

Sterken, Elmer; Ogawa, Kazuo; Tokutsu, Ichiro

2016-01-01

We analyze the impact of international R&D spillovers on recipient countries in terms of social and private returns. We divide the aggregate R&D stock by the business, government and education sectors and examine the impact on Total Factor Productivity. We endogenize the accrual of the R&D stocks by

Subsidizing R&D cooperatives

NARCIS (Netherlands)

Hinloopen, J.

2001-01-01

A framework is developed with which the implementation of two commonly used R&D-stimulating policies can be evaluated: providing R&D subsidies and sustaining the formation of R&D cooperatives. Subsidized R&D cooperatives can also be analyzed. The analysis shows that providing R&D subsidies is more

Journal of Special Operations Medicine, Volume 3, Edition 2

Science.gov (United States)

2003-01-01

types of fluids and drugs uti - lized and their rates of infusion, as well as the poten- tial for intraosseous infusion in military operations. Many of...Pharmacologic Basis of Therapeutics. Tenth edition: 695 16. American Society of Health-System Pharmacists : AHFS Drug Information. Bethesda, Maryland

3rd International Doctoral Symposium on Applied Computation and Security Systems

CERN Document Server

Saeed, Khalid; Cortesi, Agostino; Chaki, Nabendu

2017-01-01

This book presents extended versions of papers originally presented and discussed at the 3rd International Doctoral Symposium on Applied Computation and Security Systems (ACSS 2016) held from August 12 to 14, 2016 in Kolkata, India. The symposium was jointly organized by the AGH University of Science & Technology, Cracow, Poland; Ca’ Foscari University, Venice, Italy; and the University of Calcutta, India. The book is divided into two volumes, Volumes 3 and 4, and presents dissertation works in the areas of Image Processing, Biometrics-based Authentication, Soft Computing, Data Mining, Next-Generation Networking and Network Security, Remote Healthcare, Communications, Embedded Systems, Software Engineering and Service Engineering. The first two volumes of the book published the works presented at the ACSS 2015, which was held from May 23 to 25, 2015 in Kolkata, India.

SuperB R&D computing program: HTTP direct access to distributed resources

Science.gov (United States)

Fella, A.; Bianchi, F.; Ciaschini, V.; Corvo, M.; Delprete, D.; Diacono, D.; Di Simone, A.; Franchini, P.; Donvito, G.; Giacomini, F.; Gianoli, A.; Longo, S.; Luitz, S.; Luppi, E.; Manzali, M.; Pardi, S.; Perez, A.; Rama, M.; Russo, G.; Santeramo, B.; Stroili, R.; Tomassetti, L.

2012-12-01

The SuperB asymmetric energy e+e- collider and detector to be built at the newly founded Nicola Cabibbo Lab will provide a uniquely sensitive probe of New Physics in the flavor sector of the Standard Model. Studying minute effects in the heavy quark and heavy lepton sectors requires a data sample of 75 ab-1 and a luminosity target of 1036cm-2s-1. The increasing network performance also in the Wide Area Network environment and the capability to read data remotely with good efficiency are providing new possibilities and opening new scenarios in the data access field. Subjects like data access and data availability in a distributed environment are key points in the definition of the computing model for an HEP experiment like SuperB. R&D efforts in such a field have been brought on during the last year in order to release the Computing Technical Design Report within 2013. WAN direct access to data has been identified as one of the more interesting viable option; robust and reliable protocols as HTTP/WebDAV and xrootd are the subjects of a specific R&D line in a mid-term scenario. In this work we present the R&D results obtained in the study of new data access technologies for typical HEP use cases, focusing on specific protocols such as HTTP and WebDAV in Wide Area Network scenarios. Reports on efficiency, performance and reliability tests performed in a data analysis context have been described. Future R&D plan includes HTTP and xrootd protocols comparison tests, in terms of performance, efficiency, security and features available.

R&D 100 Awards | NREL

Science.gov (United States)

R&D 100 Awards R&D 100 Awards NREL has won 61 R&D 100 Awards. Widely recognized as the Oscars of Invention, the R&D 100 Awards are presented by R&D Magazine to identify and celebrate the top technological advances of the year. Recent R&D 100 Awards 2016 NREL engineers Chuck Booten

RD-MolPack technology for the constitutive production of self-inactivating lentiviral vectors pseudotyped with the nontoxic RD114-TR envelope.

Science.gov (United States)

Marin, Virna; Stornaiuolo, Anna; Piovan, Claudia; Corna, Stefano; Bossi, Sergio; Pema, Monika; Giuliani, Erica; Scavullo, Cinzia; Zucchelli, Eleonora; Bordignon, Claudio; Rizzardi, Gian Paolo; Bovolenta, Chiara

2016-01-01

To date, gene therapy with transiently derived lentivectors has been very successful to cure rare infant genetic diseases. However, transient manufacturing is unfeasible to treat adult malignancies because large vector lots are required. By contrast, stable manufacturing is the best option for high-incidence diseases since it reduces the production cost, which is the major current limitation to scale up the transient methods. We have previously developed the proprietary RD2-MolPack technology for the stable production of second-generation lentivectors, based on the RD114-TR envelope. Of note, opposite to vesicular stomatitis virus glycoprotein (VSV-G) envelope, RD114-TR does not need inducible expression thanks to lack of toxicity. Here, we present the construction of RD2- and RD3-MolPack cells for the production of self-inactivating lentivectors expressing green fluorescent protein (GFP) as a proof-of-concept of the feasibility and safety of this technology before its later therapeutic exploitation. We report that human T lymphocytes transduced with self-inactivating lentivectors derived from RD3-MolPack cells or with self-inactivating VSV-G pseudotyped lentivectors derived from transient transfection show identical T-cell memory differentiation phenotype and comparable transduction efficiency in all T-cell subsets. RD-MolPack technology represents, therefore, a straightforward tool to simplify and standardize lentivector manufacturing to engineer T-cells for frontline immunotherapy applications.

3rd International Meeting for Researchers in Materials and Plasma Technology (IMRMPT) and 1st Symposium on Nanoscience and Nanotechnology

International Nuclear Information System (INIS)

2016-01-01

These proceedings present the written contributions of the participants of the 3rd International Meeting for Researchers in Materials and Plasma Technology (3rd IMRMPT) and the 1st Symposium on Nanoscience and Nanotechnology which was held from 4 to May 9, 2015 at the Dann Carlton Hotel Bucaramanga, Colombia, organized by the faculty of science of the Universidad Industrial de Santander (UIS) and the basic science department of the Universidad Pontificia Bolivariana. This was the third version of biennial meetings that began in 2011. The five-day scientific program of the 3rd IMRMPT consisted of 24 Magisterial Conferences, 70 Oral Presentations, 185 Poster Presentations, 3 Courses and 1 Discussion Panel with the participation of undergraduate and graduate students, professors, researchers and entrepreneurs from Colombia, Russia, Germany, France, Spain, England, United States, Mexico, Argentina, Uruguay, Brazil, Venezuela, among others. Moreover, the objective of IMRMPT was to bring together national and international researchers in order to establish a network of scientific cooperation with a global impact in the area of the science and the technology of materials; to promote the exchange of creative ideas and the effective transfer of scientific knowledge, from fundamental research to innovation applied to industrial solutions and to advances in the development of new research allowing to increase the lifetime of the materials used in the industry by means of efficient transference of the knowledge between sectors academia and industry. The topics covered in the 3rd IMRMPT include New Materials, Surface Physics, Structural Integrity, Renewable Energy, Online Process Control, Non Destructive Evaluation, Characterization of Materials, Laser and Hybrid Processes, Thin Films and Nanomaterials, Surface Hardening Processes, Wear and Corrosion/Oxidation, Plasma Applications and Technologies, Modelling, Simulation and Diagnostics, Biomedical Coatings, Surface Treatments

The standard for program management

CERN Document Server

2017-01-01

The Standard for Program Management – Fourth Edition differs from prior editions by focusing on the principles of good program management. Program activities have been realigned to program lifecycle phases rather than topics, and the first section was expanded to address the key roles of program manager, program sponsor and program management office. It has also been updated to better align with PMI’s Governance of Portfolios, Programs, and Projects: A Practice Guide.

Linac-augmented light sources : an incremental concept for enhancing the capabilities of existing 3rd-generation storage rings

International Nuclear Information System (INIS)

Lewellen, J. W.

2003-01-01

Planned and proposed 4th-generation x-ray sources, such as energy-recovery linacs (ERLs) and single-pass x-ray free-electron lasers (X-FELs) offer a number of potential advantages, including small source size, higher peak brightness, ultrashort pulses, and potentially temporally and transversely coherent pulses. While offering unique capabilities, such facilities will also offer several important limitations, including limited numbers of user beamlines (for FELs) and a pulse-repetition rate that may be too high for many dynamics experiments (ERLs). In addition, there are many technical challenges associated with both types of facilities. A third type of facility, exemplified by the Short Pulse Photon Source (SPPS) at SLAC [1], would support neither a large number of users simultaneously nor generate coherent pulses, but would generate very intense, short x-ray pulses. Such a facility could serve as the starting point for either an ERL or an X-FEL, or a combined, hybrid machine. For the foreseeable future, however, existing 3rd-generation light source storage rings, such as the Advanced Photon Source, will continue to play important roles in supporting scientific research utilizing high-brightness x-rays. Existing facilities offer the powerful combination of a large number of user beamlines, efficient use of electron beam energy, and established user communities, and a program of incremental investment in, and improvements to, these facilities should continue to pay dividends into the future. This document discusses potential upgrade paths based on the Advanced Photon Source (APS) as a model 3rd-generation facility. If existing 3rd-generation facilities are to remain centers of excellence for light source-based research into the future, they must not only maintain and enhance their support of their existing user base, but also seek to expand their capabilities to support additional classes of users. There are several paths available toward this goal. The APS is

R&D program benefits estimation: DOE Office of Electricity Delivery and Energy Reliability

Energy Technology Data Exchange (ETDEWEB)

None, None

2006-12-04

The overall mission of the U.S. Department of Energy’s Office of Electricity Delivery and Energy Reliability (OE) is to lead national efforts to modernize the electric grid, enhance the security and reliability of the energy infrastructure, and facilitate recovery from disruptions to the energy supply. In support of this mission, OE conducts a portfolio of research and development (R&D) activities to advance technologies to enhance electric power delivery. Multiple benefits are anticipated to result from the deployment of these technologies, including higher quality and more reliable power, energy savings, and lower cost electricity. In addition, OE engages State and local government decision-makers and the private sector to address issues related to the reliability and security of the grid, including responding to national emergencies that affect energy delivery. The OE R&D activities are comprised of four R&D lines: High Temperature Superconductivity (HTS), Visualization and Controls (V&C), Energy Storage and Power Electronics (ES&PE), and Distributed Systems Integration (DSI).

Building monument materials during the 3rd-4rd millennium (Portugal)

Science.gov (United States)

Moita, Patricia; Pedro, Jorge; Boaventura, Rui; Mataloto, Rui; Maximo, Jaime; Almeida, Luís; Nogueira, Pedro

2014-05-01

Dolmens are the most conspicuous remains of the populations of the 4th and first half of 3rd millennia BCE. These tombs are impressive not only for their monumentality, but also because of the socioeconomic investment they represent for those Neolithic communities, namely from the Central-South of Portugal, who built them. Although dolmens have been studied for their funerary content and typologies, an interdisciplinary approach toward the geological characterization and sourcing of stones used in these constructions has not received enough attention from researchers. With MEGAGEO project a multidisciplinary group of geologist and archaeologists intends to assess the relationship between the distribution of dolmens in Central-South Portugal, their source materials, and the geological landscape. GIS will map the information gathered and will be used to analyse these relationships. The selection of the areas, with distinctive geologies (limestone vs granite), will allow to verify if human patterns of behaviour regarding the selection of megaliths are similar or different regionally. Geologically the first target area (Freixo, Alentejo) is dominated by a small intrusion of gabbro mingled/mixed within a granodioritic intrusion both related with variscan orogeny. Granodiorite exhibit several enclaves of igneous and metamorphic nature attesting the interaction between both igneous rocks as well with enclosing gneisses. Despite Alentejo region have a reduced number of outcrops the granodiorite provides rounded to tabular metric blocks. The gabbro is very coarse grained, sometimes with a cumulate texture, and their fracturing and weathering provide very fresh tabular blocks. The five studied dolmens (Quinta do Freixo #1 to #5) are implanted in a large granodioritic intrusion, around the gabbroic rocks, within an area of approximately 9km2. The medium grained granodiorite is ubiquity in all the dolmens slabs and occasionally it can be observed features of mixing and

The OIT Times, Fall 2000 edition, Vol. 3, No. 4

Energy Technology Data Exchange (ETDEWEB)

Sousa, L.

2000-09-19

This is the Fall 2000 edition of the OIT Times newsletter, a 12-page quarterly publication produced by the Office of Industrial Technologies. This issue focuses on OIT's BestPractices initiative.

Multiplex editing system

DEFF Research Database (Denmark)

2015-01-01

The present invention relates to a multiplex editing system. The system allows multiple editing of nucleic acid sequences such as genomic sequences, such as knockins of genes of interest in a genome, knockouts of genomic sequences and/or allele replacement. Also provided herein are a method...... for editing nucleic acids and a cell comprising a stably integrated endonuclease....

83rd Annual Meeting of the Eastern Psychological Association

Directory of Open Access Journals (Sweden)

I A Novikova

2012-06-01

Full Text Available A brief review of the International Program of the 83rd Annual Meeting of the Eastern Psychological Association (EPA that took place on 1-4 March 2012 in Pittsburgh (USA is submitted in the publication.

ExpEdit: a webserver to explore human RNA editing in RNA-Seq experiments.

Science.gov (United States)

Picardi, Ernesto; D'Antonio, Mattia; Carrabino, Danilo; Castrignanò, Tiziana; Pesole, Graziano

2011-05-01

ExpEdit is a web application for assessing RNA editing in human at known or user-specified sites supported by transcript data obtained by RNA-Seq experiments. Mapping data (in SAM/BAM format) or directly sequence reads [in FASTQ/short read archive (SRA) format] can be provided as input to carry out a comparative analysis against a large collection of known editing sites collected in DARNED database as well as other user-provided potentially edited positions. Results are shown as dynamic tables containing University of California, Santa Cruz (UCSC) links for a quick examination of the genomic context. ExpEdit is freely available on the web at http://www.caspur.it/ExpEdit/.

Motors of Change for R&D and Innovation towards Sustainable Energy in Turkey

Directory of Open Access Journals (Sweden)

Şiir Kılkış

2014-04-01

Full Text Available There is a revival of mission-oriented R&D and innovation programs in prioritized areas that serve the aim of decoupling economic growth from environmental pressures. This paper analyzes the governance process in activating the innovation actors in the area of energy technologies in Turkey. This process that was coordinated by TÜBİTAK led to the National Energy R&D and Innovation Strategy for 2011-2016. The three main phases of this process are mapped to be strategy-building, prioritization, and implementation involving six different participatory approaches. The Strategy is based on the strategic aims of mission-oriented R&D projects, capacity advancement, commercialization, and governance. Two new, call-based grant programs launched with eleven energy calls in the first year are overviewed. These programs were key to activating a phase known as “motors of change” for the innovation system. The second year led to the selection of the topic of “Energy Efficiency” for a pilot technology roadmap process, which involved a separate, multi-actor governance process. The paper concludes with the key role of R&D and innovation in allowing energy to contribute to the sustainable development of Turkey by utilizing energy resources effectively and efficiently.

Export performance and investment in R&D

DEFF Research Database (Denmark)

Smith, Valdemar; Madsen, Erik Strøjer; Dilling-Hansen, Mogens

2002-01-01

This paper analyses the role of R&D in the export behaviour of Danish firms. Export behaviour is defined as the export intensity and the likelihood of a firm being an exporter. In the theoretical part of the paper it is argued that export and being R&D active are endogenous with respect to each...... other, and an empirical model is formulated in order to estimate which factors affect the firm's export. It is argued that besides R&D, firm size, wages and a number of other firm-specific factors controlling for risks are highly important for the export performance. In the empirical part of the paper...... the model is tested on a sample of 3,500 Danish firms. Using a FIML estimation form in order to deal with endogeneity problems between the R&D and export decisions of the firms, the computation clearly verifies the theoretical model put forward. Moreover, R&D is an important factor for being an exporting...

Do R&D Investments Affect Export Performance?

DEFF Research Database (Denmark)

Smith, Valdemar; Madsen, Erik Strøjer; Dilling-Hansen, Mogens

2002-01-01

This paper analyses the role of R&D in the export behaviour of Danish firms. Export behaviour is defined as the export intensity and the likelihood of a firm being an exporter. In the theoretical part of the paper it is argued that export and being R&D active are endogenous with respect to each...... other, and an empirical model is formulated in order to estimate which factors affect the firm's export. It is argued that besides R&D, firm size, wages and a number of other firm-specific factors controlling for risks are highly important for the export performance. In the empirical part of the paper...... the model is tested on a sample of 3,500 Danish firms. Using a FIML estimation form in order to deal with endogeneity problems between the R&D and export decisions of the firms, the computation clearly verifies the theoretical model put forward. Moreover, R&D is an important factor for being an exporting...

Prophyrin identification by 3rd derivative UV/VIS spectroscopy

International Nuclear Information System (INIS)

Freeman, D.H.; Saint Martin, D.C.; Boreham, C.J.

1992-01-01

This patent describes the Soret band wavelength of nickel and vanadyl porphyrins λ Soret, which identifies etic DPEP/di-DPEP, propano and butano structure types. The approach is based upon routine diode array uv/vis spectra taken to their 3rd derivative. an interpolated zero crossing gives λ max within 0.1 nm. Accordingly, reference spectral properties of 27 well characterized metalloporphyrins were determined. When λSoret, λα and λβ and molecular mass data were combined, each of the DPEP and di-DPEP nickel complexes were distinct. In addition, λSoret was able to classify nickel etioporphyrins according to the number of beta hydrogens. To illustrate the many possible applications, two substances were isolated by HPLC from a Messel Shale extract based on known HPLC C18 retentions. Comparison of wavelength and mass between isolated and reference counterparts showed precise agreement. Thus uv/vic spectroscopy helps to classify porphyrin structure, and to facilitate identification by matching to reference data

EMCS upgrade to 3rd generation not an easy task

International Nuclear Information System (INIS)

Neal, C.E.

1993-01-01

The Energy Management Control System (EMCS) for Sheppard AFB was started in 1976 with contract completion in 1981. With other additions the system grew to over 8,000 points with 350 Field Panels. Over 35 miles of coax for data transmission were installed. In 1987 an effort was started to move to the open-quotes newclose quotes generation for the central system. At the same time coax replacement with fiber optics was started. This paper discusses the problems encountered which caused a change in plans and a move to 3rd generation system. There are many things to consider when attempting an upgrade. Conflicting information will make the task that much harder. This paper will attempt to show some of the problems encountered and lessons learned to help others avoid such difficulties

Organizational Knowledge Communication – a Nascent 3rd Order Disciplinarity

DEFF Research Database (Denmark)

Kastberg, Peter

2014-01-01

There is an emerging tendency that the organizational communication functions of larger companies enter into a symbiotic relationship with the companies’ Knowledge Management function. A tendency this journal has labelled Organizational Knowledge Communication. This should come as no surprise...... to neither the researcher nor the practitioner; after all who can say where a corporation’s knowledge work ends and where its organizational communication begins – and vice versa? In this paper I will present a theoretical account of the three disciplinary trajectories that, in my view, have given rise...... to Organizational Knowledge Communication, i.e., organization studies, communication theory and Knowledge Management, respectively. In their synthesis the three trajectories form a disciplinary triple helix, a triple helix which, in turn, gives rise to Organizational Knowledge Communication as a novel, 3rd order...

Single-edition quadrangle maps

Science.gov (United States)

,

1998-01-01

In August 1993, the U.S. Geological Survey's (USGS) National Mapping Division and the U.S. Department of Agriculture's Forest Service signed an Interagency Agreement to begin a single-edition joint mapping program. This agreement established the coordination for producing and maintaining single-edition primary series topographic maps for quadrangles containing National Forest System lands. The joint mapping program saves money by eliminating duplication of effort by the agencies and results in a more frequent revision cycle for quadrangles containing national forests. Maps are revised on the basis of jointly developed standards and contain normal features mapped by the USGS, as well as additional features required for efficient management of National Forest System lands. Single-edition maps look slightly different but meet the content, accuracy, and quality criteria of other USGS products. The Forest Service is responsible for the land management of more than 191 million acres of land throughout the continental United States, Alaska, and Puerto Rico, including 155 national forests and 20 national grasslands. These areas make up the National Forest System lands and comprise more than 10,600 of the 56,000 primary series 7.5-minute quadrangle maps (15-minute in Alaska) covering the United States. The Forest Service has assumed responsibility for maintaining these maps, and the USGS remains responsible for printing and distributing them. Before the agreement, both agencies published similar maps of the same areas. The maps were used for different purposes, but had comparable types of features that were revised at different times. Now, the two products have been combined into one so that the revision cycle is stabilized and only one agency revises the maps, thus increasing the number of current maps available for National Forest System lands. This agreement has improved service to the public by requiring that the agencies share the same maps and that the maps meet a

Influence of the 1st, 2nd and 3rd harmonic magnetic field in mini-cyclotron

International Nuclear Information System (INIS)

Lu xiangshun; Chen Maobai; Li Deming; Xu Senlin

1996-01-01

The influence of the 1st, 2nd and 3rd harmonic magnetic field on particle's movement in the mini-cyclotron has been studied. The permitted upper limits for each harmonic part are calculated. These data provide a theoretical reference for magnetic trimming

Development and Demonstration (RD and D) Plan for the disposal of radioactive waste in Switzerland

Energy Technology Data Exchange (ETDEWEB)

NONE

2016-12-15

This comprehensive brochure published by the Swiss National Cooperative for the Disposal of Radioactive Waste (NAGRA) discusses NAGRA’s Research, Development and Demonstration (RD and D) Plan together with its Waste Management Program. The present RD and D Plan is in line with the Swiss Federal Council’s decision and in accordance with the regulatory framework in Switzerland. The two types of repository foreseen, one for low- and intermediate-level waste (L/ILW) and one for vitrified high-level waste are discussed. The overall objectives of this report are stated and the planning premises for implementation of the repositories are discussed, as are the strategic requirements involved and the stages of their implementation. The methodology and the resources available for implementing the RD and D programme are described. The status of the RD and D program is noted and an overview of the technical program for the next 10 years is presented. The report includes many diagrams, illustrations and tables and describes activities at various research installations in Switzerland.

Development and Demonstration (RD and D) Plan for the disposal of radioactive waste in Switzerland

International Nuclear Information System (INIS)

2016-12-01

This comprehensive brochure published by the Swiss National Cooperative for the Disposal of Radioactive Waste (NAGRA) discusses NAGRA’s Research, Development and Demonstration (RD and D) Plan together with its Waste Management Program. The present RD and D Plan is in line with the Swiss Federal Council’s decision and in accordance with the regulatory framework in Switzerland. The two types of repository foreseen, one for low- and intermediate-level waste (L/ILW) and one for vitrified high-level waste are discussed. The overall objectives of this report are stated and the planning premises for implementation of the repositories are discussed, as are the strategic requirements involved and the stages of their implementation. The methodology and the resources available for implementing the RD and D programme are described. The status of the RD and D program is noted and an overview of the technical program for the next 10 years is presented. The report includes many diagrams, illustrations and tables and describes activities at various research installations in Switzerland

Safety management of a complex R&D ground operating system

Science.gov (United States)

Connors, J.; Mauer, R. A.

1975-01-01

Report discusses safety program implementation for large R&D operating system. Analytical techniques are defined and suggested as tools for identifying potential hazards and determining means to effectively control or eliminate hazards.

Optimizing the Level of Renewable Electric R&D Expenditures Using Real Options Analysis

Energy Technology Data Exchange (ETDEWEB)

Davis, G.; Owens, B.

2003-02-01

One of the primary objectives of the United States' federal non-hydro renewable electric R&D program is to promote the development of technologies that have the potential to provide consumers with stable and secure energy supplies. In order to quantify the benefits provided by continued federal renewable electric R&D, this paper uses ''real option'' pricing techniques to estimate the value of renewable electric technologies in the face of uncertain fossil fuel prices. Within the real options analysis framework, the current value of expected future supply from renewable electric technologies, net of federal R&D expenditures, is estimated to be $30.6 billion. Of this value, 86% can be attributed to past federal R&D efforts, and 14% can be attributed to future federal R&D efforts, assuming continued federal R&D funding at $300 million/year. In addition, real options analysis shows that the value of renewable electric technologies increases as current and future R&D funding levels increase. This indicates that the current level of federal renewable electric R&D funding is sub-optimal low.

ChemSession'06 - 3rd Seminary of Warsaw PhD Students in Chemistry. Abstracts

International Nuclear Information System (INIS)

Zachara, J.; Lulinski, S.; Dobrowolski, J.C.; Raczynska, E.D.; Fuks, L.; Cyranski, M.K.; Stepien, B.T.; Sawicki, M.G.

2006-01-01

3 rd Annual Seminary of Warsaw PhD Students in Chemistry presented the latest achievements in chemistry, obtained in all Warsaw universities and scientific institutes. In 2006 participants presented 4 plenary lectures, and 109 posters. Among others, posters covered four disciplines related to the nuclear sciences: (a) radiobiology and radiotherapy, (b) radiation chemistry and photochemistry, (c) isotopic effects in chemistry, and (d) chemical technology

3rd International Arab Forensic Sciences & Forensic Medicine Conference, ASFSFM 2017: Conference Report

Directory of Open Access Journals (Sweden)

Abdulsallam A. Bakdash

2017-12-01

Full Text Available The Arab Society for Forensic Sciences and Forensic Medicine (ASFSFM at Naif Arab University for Security Sciences seeks to present the latest developments in all fields of forensic sciences through holding specialized scientific events and academic activities. This is also achieved through its periodic scientific peer-reviewed journal, the Arab Journal of Forensic Sciences and Forensic Medicine. It also seeks to promote scientific research in all fields of forensic science and forensic medicine, and seeks actively to contribute in holding scientific meetings in accordance with advanced scientific standards, including the 3rd International Arab Forensic Sciences & Forensic Medicine Conference. This important event was attended by scientists and experts from various fields of criminal and forensic sciences from both Arab and non-Arab countries. This conference was a significant scientific accomplishment that contributed to the advancement of forensic sciences and forensic medicine in the Arab world. The conference aimed, in accordance with the vision of Naif Arab University for Security Sciences, to enhance peace, security and justice in Arab societies.  Naif Arab University for Security Sciences, represented by the Arab Society for Forensic Sciences and Forensic Medicine, held the 3rd International Arab Forensic Sciences & Forensic Medicine Conference on the University's campus during the period from 21st to 23rd November 2017. The event included the participation of more than 720 experts in forensic sciences and forensic medicine from 33 countries all over the world. Experts discussed and presented the latest developments in their fields. The conference provided a creative environment for students from both local and international universities to benefit from experts and specialists, and to access the most recent research.  On behalf of His Excellency the president of Naif Arab University for Security Sciences, and the Arab Society for

Oxyacetylene Welding and Oxyfuel Cutting. Third Edition. Teacher Edition [and] Student Edition [and] Student Workbook.

Science.gov (United States)

Knapp, John; Harper, Eddie

This Oklahoma curriculum guide, which includes a teacher edition, a student edition, and a student workbook, provides three units for a course on oxyacetylene welding, oxyfuel cutting, and cutting done with alternative fuels such as MAPP, propane, and natural gas. The three units are: "Oxyacetylene Welding"; "Oxyfuel Cutting";…

A Randomized Controlled Trial for Children with Childhood Apraxia of Speech Comparing Rapid Syllable Transition Treatment and the Nuffield Dyspraxia Programme-Third Edition

Science.gov (United States)

Murray, Elizabeth; McCabe, Patricia; Ballard, Kirrie J.

2015-01-01

Purpose: This randomized controlled trial compared the experimental Rapid Syllable Transition (ReST) treatment to the Nuffield Dyspraxia Programme-Third Edition (NDP3; Williams & Stephens, 2004), used widely in clinical practice in Australia and the United Kingdom. Both programs aim to improve speech motor planning/programming for children…

Different effects of valproic acid on photoreceptor loss in Rd1 and Rd10 retinal degeneration mice.

Science.gov (United States)

Mitton, Kenneth P; Guzman, Alvaro E; Deshpande, Mrinalini; Byrd, David; DeLooff, Camryn; Mkoyan, Kristina; Zlojutro, Paul; Wallace, Adrianne; Metcalf, Brandon; Laux, Kirsten; Sotzen, Jason; Tran, Trung

2014-01-01

The histone-deacetylase inhibitor activity of valproic acid (VPA) was discovered after VPA's adoption as an anticonvulsant. This generated speculation for VPA's potential to increase the expression of neuroprotective genes. Clinical trials for retinitis pigmentosa (RP) are currently active, testing VPA's potential to reduce photoreceptor loss; however, we lack information regarding the effects of VPA on available mammalian models of retinal degeneration, nor do we know if retinal gene expression is perturbed by VPA in a predictable way. Thus, we examined the effects of systemic VPA on neurotrophic factor and Nrl-related gene expression in the mouse retina and compared VPA's effects on the rate of photoreceptor loss in two strains of mice, Pde6b(rd1/rd1) and Pde6b(rd10/rd10) . The expression of Bdnf, Gdnf, Cntf, and Fgf2 was measured by quantitative PCR after single and multiple doses of VPA (intraperitoneal) in wild-type and Pde6b(rd1/rd1) mice. Pde6b(rd1/rd1) mice were treated with daily doses of VPA during the period of rapid photoreceptor loss. Pde6b(rd10/rd10) mice were also treated with systemic VPA to compare in a partial loss-of-function model. Retinal morphology was assessed by virtual microscopy or spectral-domain optical coherence tomography (SD-OCT). Full-field and focal electroretinography (ERG) analysis were employed with Pde6b(rd10/rd10) mice to measure retinal function. In wild-type postnatal mice, a single VPA dose increased the expression of Bdnf and Gdnf in the neural retina after 18 h, while the expression of Cntf was reduced by 70%. Daily dosing of wild-type mice from postnatal day P17 to P28 resulted in smaller increases in Bdnf and Gdnf expression, normal Cntf expression, and reduced Fgf2 expression (25%). Nrl gene expression was decreased by 50%, while Crx gene expression was not affected. Rod-specific expression of Mef2c and Nr2e3 was decreased substantially by VPA treatment, while Rhodopsin and Pde6b gene expression was normal at P28. Daily

CELEBRATION OF DECEMBER 3RD, INTERNATIONAL DAY OF PERSONS WITH DISABILITIES

Directory of Open Access Journals (Sweden)

Maja FILIPOVSKA

2017-03-01

Full Text Available On December 2nd 2016 in the main amphitheater at the Faculty of Philosophy in Skopje, was held the celebration of December 3rd, the International Day of Persons with Disabilities, in organization of the Institute of Special Education and Rehabilitation. The official part of the program was started with a speech by Goran Ajdinski, PhD, the Dean of the Faculty of Philosophy in Skopje. The guests at the celebration were also greeted by the Rector of the University “Ss. Cyril and Methodius” – Skopje, Nikola Jankulovski, PhD and the Minister of Labor and Social Policy of Republic of Macedonia, Frosina Tashevska-Remenski, PhD. After the speeches, which highlighted the current efforts and future commitment to inclusion and accessibility of persons with disabilities, two awards were presented by the Humanitarian foundation “Prof. d-r Ljupco Ajdinski”. The first award was given to Simona Kostadinova as the student with achieved highest grade point average of 9.65 in the generation 2011/12 during the studies of Special education and rehabilitation. The second award was intended for the highest ranked student at the university admission in 2016/2017. This award belonged to Nadica Gjerasimova who had 97.70 points on the official rank list. Beside the awards, two acknowledgements for humanity were also given by the Foundation “Prof. d-r Ljupco Ajdinski”. For the longstanding human activity in preparation of special education and rehabilitation staff and education and rehabilitation of persons with disabilities, the first acknowledgement was given to the Institute of Special education and rehabilitation. The second acknowledgement was meant for Kiril Temkov, PhD, about his numerous initiated and organized human activities, especially for the published paper on the ethical dimensions of special education and rehabilitation and introduction of Ethics in the education system in Republic of Macedonia. The last part of the program was intended for

PreK-3rd: What Is the Price Tag? Policy to Action Brief. No. 2

Science.gov (United States)

Shore, Rima

2009-01-01

In an era of intense fiscal pressures, educators are focusing on those investments most likely to lift student achievement. They are also trying to make more strategic use of existing resources. To achieve these goals, a growing number of policymakers are considering integrated PreK-3rd approaches. Increasingly, they are recognizing that the first…

Offshoring R&D

DEFF Research Database (Denmark)

Hansen, Zaza Nadja Lee; Rasmussen, Lauge Baungaard

2010-01-01

Companies are increasingly offshoring R&D activities. Many firms, however, experience difficulties related to virtual teamwork across cultures and time zones. The research question is: How does increasing R&D offshoring impact transparency of communication structures and knowledge sharing? Using...... case studies from Danish multinational corporations with R&D activities in China, India or Eastern Europe this paper analyses the impact observed in these companies in regard to communication structures and knowledge sharing in management of offshored R&D activities. The findings show that companies...... attempt to increase transparency through formalisation of knowledge and clear communication structures. However, the influence of tacit knowledge, horizontal communication and culture seem largely overlooked. Therefore the authors suggest a context based approach to transparency accustomed...

Formal faculty observation and assessment of bedside skills for 3rd-year neurology clerks.

Science.gov (United States)

Thompson Stone, Robert; Mooney, Christopher; Wexler, Erika; Mink, Jonathan; Post, Jennifer; Jozefowicz, Ralph F

2016-11-22

To evaluate the feasibility and utility of instituting a formalized bedside skills evaluation (BSE) for 3rd-year medical students on the neurology clerkship. A neurologic BSE was developed for 3rd - year neurology clerks at the University of Rochester for the 2012-2014 academic years. Faculty directly observed 189 students completing a full history and neurologic examination on real inpatients. Mock grades were calculated utilizing the BSE in the final grade, and number of students with a grade difference was determined when compared to true grade. Correlation was explored between the BSE and clinical scores, National Board of Medical Examiners (NBME) scores, case complexity, and true final grades. A survey was administered to students to assess their clinical skills exposure and the usefulness of the BSE. Faculty completed and submitted a BSE form for 88.3% of students. There was a mock final grade change for 13.2% of students. Correlation coefficients between BSE score and clinical score/NBME score were 0.36 and 0.35, respectively. A statistically significant effect of BSE was found on final clerkship grade (F 2,186 = 31.9, p neurology clerkship was feasible. Low correlation between BSE score and other evaluations indicated a unique measurement to contribute to student grade. Using real patients with differing case complexity did not alter the grade. © 2016 American Academy of Neurology.

An Implementation Guide for Intermodal Transportation Career Education. Revised Edition.

Science.gov (United States)

Associated Research Corp., South Miami, FL.

One of a series devoted to career education in transportation, this teachers' guide, which is a revised edition of a guide issued in 1974, covers the planning, implementation, and evaluation of programs in transportation career education and provides forms to be used in these three processes. The most important principles in program planning are…

3rd symposium on tires and chassis; 3. Symposium Reifen und Fahrwerk

Energy Technology Data Exchange (ETDEWEB)

Geringer, B.; Stumpf, H. (comps.)

2005-07-01

The present volume contains the talks, which were held at the 3rd symposium on ''Tires and chassis'' at the Institute for combustion machines at the Technical University Vienna on 26th September 2005 in cooperation with UAMTTC and Semperit Reifen Ges.m.H. Apart from technical improvements on chassis, tires and carriageway the overall perspective will get more important in the future, which also includes the driver, the neighbour, the environment and the traffic policy. Due to an increasing number of international participants, discussions can be expected, which will take into consideration extraordinary and manifold perspectives. The third symposium on ''Tires and chassis'' discusses the following developments, of which some are evolutionary. (a) Tire engineering; environmental aspects of tires, roll resistance of tires, driving comfort of tires, winter tires for passenger vehicles and trucks. (b) vehicle engineering, engineering of a race car chassis by means of telemetric measuring data acquisition; simulation of steering wheel vibrations on a complete vehicle test stand. (c) Vehicle steering; chassis of tracklaying vehicles; automatic air pressure control. (orig.)

LevelMerge: Collaborative Game Level Editing by Merging Labeled Graphs

OpenAIRE

Santoni, Christian; Salvati, Gabriele; Tibaldo, Valentina; Pellacini, Fabio

2016-01-01

Game level editing is the process of constructing a full game level starting from 3D asset libraries, e.g. 3d models, textures, shaders, scripts. In level editing, designers define the look and behavior of the whole level by placing objects, assigning materials and lighting parameters, setting animations and physics properties and customizing the objects AI and behavior by editing scripts. The heterogeneity of the task usually translates to a workflow where a team of people, experts on separa...

Academic Training: 3rd Term - 01 April - 30 June 2005

CERN Multimedia

Françoise Benz

2005-01-01

2004 - 2005 ACADEMIC TRAINING PROGRAMME 3rd Term - 01 April - 30 June 2005 REGULAR LECTURE PROGRAMME Monte Carlo generators fot the LHC by T. Sjostrand / CERN-PH 4, 5, 6, 7 April The LHC machine experiment interface by S. Tapprogge / Univ. Gutenberg, Mainz, D R. Assmann, CERN-AB, E. Tsesmelis and D. Macina / CERN-TS 18, 19, 20, 21, 22 April Cosmology for particle physicists by S. Carroll / Univ. of Chicago, USA 9, 10, 11, 12, 13 May The ITER projects: technological challenges by P. Bruzzone / EPFL CRPP, Zürich, CH J. Lister / EPFL CRPP, Lausanne, CH 30, 31 May, 1, 2, 3 June String theory by C. Johnson / Univ. of Southern California, USA 6, 7, 8, 9, 10 June Small may be beautiful By M. Davier / LAL, Orsay, F. T. Soldner / ILL, Grenoble, F. 13, 14, 15, 16, 17 June Climate change and challenges for the environment by C. Schluchter / Univ. Bern. CH 20, 21, 22 June LECTURE SERIES FOR POSTGRADUATE STUDENTS Particle detectors - principles and techniques by C. Joram, L. Ropelewski, M. Moll, C. ...

75 FR 34450 - Filing Dates for the Indiana Special Election in the 3rd Congressional District

Science.gov (United States)

2010-06-17

... 3rd Congressional District AGENCY: Federal Election Commission. ACTION: Notice of filing dates for special election. SUMMARY: Indiana has scheduled a Special General Election on November 2, 2010, to fill.... Committees required to file reports in connection with the Special General Election on November 2, 2010...

Evolutionary analysis reveals regulatory and functional landscape of coding and non-coding RNA editing.

Science.gov (United States)

Zhang, Rui; Deng, Patricia; Jacobson, Dionna; Li, Jin Billy

2017-02-01

Adenosine-to-inosine RNA editing diversifies the transcriptome and promotes functional diversity, particularly in the brain. A plethora of editing sites has been recently identified; however, how they are selected and regulated and which are functionally important are largely unknown. Here we show the cis-regulation and stepwise selection of RNA editing during Drosophila evolution and pinpoint a large number of functional editing sites. We found that the establishment of editing and variation in editing levels across Drosophila species are largely explained and predicted by cis-regulatory elements. Furthermore, editing events that arose early in the species tree tend to be more highly edited in clusters and enriched in slowly-evolved neuronal genes, thus suggesting that the main role of RNA editing is for fine-tuning neurological functions. While nonsynonymous editing events have been long recognized as playing a functional role, in addition to nonsynonymous editing sites, a large fraction of 3'UTR editing sites is evolutionarily constrained, highly edited, and thus likely functional. We find that these 3'UTR editing events can alter mRNA stability and affect miRNA binding and thus highlight the functional roles of noncoding RNA editing. Our work, through evolutionary analyses of RNA editing in Drosophila, uncovers novel insights of RNA editing regulation as well as its functions in both coding and non-coding regions.

The ARCHER project (Advanced High-Temperature Reactors for Cogeneration of Heat and Electricity R&D)

Energy Technology Data Exchange (ETDEWEB)

Knol, S., E-mail: knol@nrg.eu [Nuclear Research and consultancy Group (NRG), PO Box 25, NL-1755 ZG Petten (Netherlands); Fütterer, M.A. [Joint Research Centre, Institute for Energy, Petten (Netherlands); Roelofs, F. [Nuclear Research and consultancy Group (NRG), PO Box 25, NL-1755 ZG Petten (Netherlands); Kohtz, N. [TÜV Rheinland, Köln (Germany); Laurie, M. [Joint Research Centre, Institute for Transuranium elements, Karlsruhe (Germany); Buckthorpe, D. [UMAN, University of Manchester, Manchester (United Kingdom); Scheuermann, W. [IKE, Stuttgart University, Stuttgart (Germany)

2016-09-15

The European HTR R&D project ARCHER (Advanced High-Temperature Reactors for Cogeneration of Heat and Electricity R&D) builds on a solid HTR technology foundation in Europe, established through former national UK and German HTR programs and in European framework programs. ARCHER runs from 2011 to 2015 and targets selected HTR R&D subjects that would specifically support demonstration, with a focus on experimental effort. In line with the R&D and deployment strategy of the European Sustainable Nuclear Energy Technology Platform (SNETP) ARCHER contributes to maintaining, strengthening and expanding the HTR knowledge base in Europe to lay the foundations for demonstration of nuclear cogeneration with HTR systems. The project consortium encompasses conventional and nuclear industry, utilities, Technical Support Organizations, R&D organizations and academia. ARCHER shares results with international partners in the Generation IV International Forum and collaborates directly with related projects in the US, China, Japan, the Republic of Korea and South Africa. The ARCHER project has finished, and the paper comprises an overview of the achievements of the project.

Changing R&D models in research-based pharmaceutical companies.

Science.gov (United States)

Schuhmacher, Alexander; Gassmann, Oliver; Hinder, Markus

2016-04-27

New drugs serving unmet medical needs are one of the key value drivers of research-based pharmaceutical companies. The efficiency of research and development (R&D), defined as the successful approval and launch of new medicines (output) in the rate of the monetary investments required for R&D (input), has declined since decades. We aimed to identify, analyze and describe the factors that impact the R&D efficiency. Based on publicly available information, we reviewed the R&D models of major research-based pharmaceutical companies and analyzed the key challenges and success factors of a sustainable R&D output. We calculated that the R&D efficiencies of major research-based pharmaceutical companies were in the range of USD 3.2-32.3 billion (2006-2014). As these numbers challenge the model of an innovation-driven pharmaceutical industry, we analyzed the concepts that companies are following to increase their R&D efficiencies: (A) Activities to reduce portfolio and project risk, (B) activities to reduce R&D costs, and (C) activities to increase the innovation potential. While category A comprises measures such as portfolio management and licensing, measures grouped in category B are outsourcing and risk-sharing in late-stage development. Companies made diverse steps to increase their innovation potential and open innovation, exemplified by open source, innovation centers, or crowdsourcing, plays a key role in doing so. In conclusion, research-based pharmaceutical companies need to be aware of the key factors, which impact the rate of innovation, R&D cost and probability of success. Depending on their company strategy and their R&D set-up they can opt for one of the following open innovators: knowledge creator, knowledge integrator or knowledge leverager.

Development of the 3rd Generation ECR ion source

International Nuclear Information System (INIS)

Lyneis, C.M.; Xie, Z.Q.; Taylor, C.E.

1997-09-01

The LBNL 3rd Generation ECR ion source has progressed from a concept to the fabrication of a full scale prototype superconducting magnet structure. This new ECR ion source will combine the recent ECR ion source techniques that significantly enhance the production of high charge state ions. The design includes a plasma chamber made from aluminum to provide additional cold electrons, three separate microwave feeds to allow multiple-frequency plasma heating (at 10, 14 and 18 GHz or at 6, 10 and 14 GHz) and very high magnetic mirror fields. The design calls for mirror fields of 4 T at injection and 3 T at extraction and for a radial field strength at the wall of 2.4 T. The prototype superconducting magnet structure which consists of three solenoid coils and six race track coils with iron poles forming the sextupole has been tested in a vertical dewar. After training, the sextupole magnet reached 105% of its design current with the solenoids off. With the solenoids operating at approximately 70% of their full design field, the sextuple coils operated at 95% of the design value which corresponds to a sextupole field strength at the plasma wall of more than 2.1 T

3rd Abel Symposium

CERN Document Server

Owren, Brynjulf

2008-01-01

The 2006 Abel symposium is focusing on contemporary research involving interaction between computer science, computational science and mathematics. In recent years, computation has been affecting pure mathematics in fundamental ways. Conversely, ideas and methods of pure mathematics are becoming increasingly important within computational and applied mathematics. At the core of computer science is the study of computability and complexity for discrete mathematical structures. Studying the foundations of computational mathematics raises similar questions concerning continuous mathematical structures. There are several reasons for these developments. The exponential growth of computing power is bringing computational methods into ever new application areas. Equally important is the advance of software and programming languages, which to an increasing degree allows the representation of abstract mathematical structures in program code. Symbolic computing is bringing algorithms from mathematical analysis into the...

3rd International Conference on Computational Mathematics and Computational Geometry

CERN Document Server

Ravindran, Anton

2016-01-01

This volume presents original research contributed to the 3rd Annual International Conference on Computational Mathematics and Computational Geometry (CMCGS 2014), organized and administered by Global Science and Technology Forum (GSTF). Computational Mathematics and Computational Geometry are closely related subjects, but are often studied by separate communities and published in different venues. This volume is unique in its combination of these topics. After the conference, which took place in Singapore, selected contributions chosen for this volume and peer-reviewed. The section on Computational Mathematics contains papers that are concerned with developing new and efficient numerical algorithms for mathematical sciences or scientific computing. They also cover analysis of such algorithms to assess accuracy and reliability. The parts of this project that are related to Computational Geometry aim to develop effective and efficient algorithms for geometrical applications such as representation and computati...

AN EXCEL-BASED DECISION SUPPORT SYSTEM FOR SCORING AND RANKING PROPOSED R&D PROJECTS

OpenAIRE

ANNE DE PIANTE HENRIKSEN; SUSAN W. PALOCSAY

2008-01-01

One of the most challenging aspects of technology management is the selection of research and development (R&D) projects from among a group of proposals. This paper introduces an interactive, user-friendly decision support system for evaluating and ranking R&D projects and demonstrates its application on an example R&D program. It employs the scoring methodology developed by Henriksen and Traynor to provide a practical technique that considers both project merit and project cost in the evalua...

Re-editing the paradigm of Cytidine (C) to Uridine (U) RNA editing.

Science.gov (United States)

Fossat, Nicolas; Tam, Patrick P L

2014-01-01

Cytidine (C) to Uridine (U) RNA editing is a post-trancriptional modification that until recently was known to only affect Apolipoprotein b (Apob) RNA and minimally require 2 components of the C to U editosome, the deaminase APOBEC1 and the RNA-binding protein A1CF. Our latest work has identified a novel RNA-binding protein, RBM47, as a core component of the editosome, which can substitute A1CF for the editing of ApoB mRNA. In addition, new RNA species that are subjected to C to U editing have been identified. Here, we highlight these recent discoveries and discuss how they change our view of the composition of the C to U editing machinery and expand our knowledge of the functional attributes of C to U RNA editing.

Sandia National Laboratories: CRISPR genome-editing technology

Science.gov (United States)

Environmental Management System Pollution Prevention History 60 impacts Diversity Locations Facts & Figures Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers

Results of the independent verification of radiological remedial action at 280 South 3rd East Street, Monticello, Utah (MS00099)

International Nuclear Information System (INIS)

Crutcher, J.W.; Wilson, M.J.

1990-02-01

In 1980 the site of a vanadium and uranium mill at Monticello, Utah, was accepted into the US Department of Energy's (DOE's) Surplus Facilities Management Program, with the objectives of restoring the government-owned mill site to safe levels of radioactivity, disposing of or containing the tailings in an environmentally safe manner, and performing remedial actions on off-site (vicinity) properties that had been contaminated by radioactive material resulting from mill operations. During 1985 and 1986, UNC Geotech, the remedial action contractor designated by DOE, performed remedial action on the vicinity property at 280 South 3rd East Street, Monticello, Utah. The Pollutant Assessments Group (PAG) of Oak Ridge National Laboratory was assigned the responsibility of verifying the data supporting the adequacy of remedial action and confirming the site's compliance with DOE guidelines. The PAG found that the site successfully meets the DOE remedial action objectives. Procedures used by PAG are described. 3 refs., 2 tabs

Results of the independent verification of radiological remedial action at 397 East 3rd South Street, Monticello, Utah (MS00168)

International Nuclear Information System (INIS)

Wilson, M.J.; Crutcher, J.W.

1991-07-01

In 1980 the site of a vanadium and uranium mill at Monticello, Utah, was accepted into the US Department of Energy's (DOE's) Surplus Facilities Management Program, with the objectives of restoring the government-owned mill site to safe levels of radioactivity, disposing of or containing the tailings in an environmentally safe manner, and performing remedial actions on off-site (vicinity) properties that had been contaminated by radioactive material resulting from mill operations. During 1987 and 1988, UNC Geotech, the remedial action contractor designated by DOE, performed remedial action on the vicinity property at 397 East 3rd South Street, Monticello, Utah. The Pollutant Assessments Group (PAG) of Oak Ridge National Laboratory was assigned the responsibility of verifying the data supporting the adequacy of remedial action and confirming the site's compliance with DOE guidelines. The PAG found that the site successfully meets the DOE remedial action objectives. Procedures used by PAG are described. 3 refs., 2 tabs

Results of the independent verification of radiological remedial action at 381 East 3rd South Street, Monticello, Utah (MS00140)

International Nuclear Information System (INIS)

Crutcher, J.W.; Smuin, M.W.

1989-10-01

In 1980 the site of a vanadium and uranium mill at Monticello, Utah, was accepted into the US Department of Energy (DOE's) Surplus Facilities Management Program, with the objectives of restoring the government-owned mill site to safe levels of radioactivity, disposing of or containing the tailings in an environmentally safe manner, and performing remedial actions on off-site (vicinity) properties that had been contaminated by radioactive material resulting from mill operations. During 1986, UNC Geotech, the remedial action contractor designated by DOE, performed remedial action on the vicinity at 381 East 3rd South Street, Monticello, Utah. The Pollutant Assessments group (PAG) of Oak Ridge National Laboratory was assigned the responsibility of verifying the data supporting the adequacy of remedial action and confirming the site's compliance with DOE guidelines. The PAG found that the site successfully meets the DOE remedial action objectives. Procedures used by PAG are described. 3 refs., 2 tabs

Results of the independent verification of radiological remedial action at 281 East 3rd South Street, Monticello, Utah (MS00138)

International Nuclear Information System (INIS)

Crutcher, J.W.; Wilson, M.J.

1990-02-01

In 1980 the site of a vanadium and uranium mill at Monticello, Utah, was accepted into the US Department of Energy's (DOE's) Surplus Facilities Management Program, with the objectives of restoring the government-owned mill site to safe levels of radioactivity, disposing of or containing the tailings in an environmentally safe manner, and performing remedial actions on off-site (vicinity) properties that had been contaminated by radioactive material resulting from mill operations. During 1985, UNC Geotech, the remedial action contractor designated by DOE, performed remedial action on the vicinity property at 281 East 3rd South Street, Monticello, Utah. The Pollutant Assessments Group (PAG) of Oak Ridge National Laboratory was assigned the responsibility of verifying the data supporting the adequacy of remedial action and confirming the site's compliance with DOE guidelines. The PAG found that the site successfully meets the DOE remedial action objectives. Procedures used by PAG are described. 3 refs., 2 tabs

Results of the independent verification of radiological remedial action at 196 East 3rd South Street, Monticello, Utah (MS00083)

International Nuclear Information System (INIS)

Crutcher, J.W.; Smuin, M.W.

1989-10-01

In 1980 the site of a vanadium and uranium mill at Monticello, Utah, was accepted into the US Department of Energy's (DOE) Surplus Facilities Management program with the objectives of restoring the government-owned mill site to safe levels of radioactivity, disposing of or containing the tailings in an environmentally safe manner, and performing remedial actions on off-site (vicinity) properties that had been contaminated by radioactive material resulting from mill operations. During 1984 and 1985, UNC Geotech, the remedial action contractor designated by DOE, performed remedial action on the vicinity property at 196 East 3rd South Street, Monticello, Utah. The Pollutant Assessments Group (PAG) of Oak Ridge National Laboratory was assigned the responsibility of verifying the data supporting the adequacy of remedial action and confirming the site's compliance with DOE guidelines. The PAG found that the site successfully meets the DOE remedial action objectives. Procedures used by PAG are described. 3 refs., 2 tabs

An introduction to Kolmogorov complexity and its applications. - 3rd edition

NARCIS (Netherlands)

Li, M.; Vitányi, P.

2008-01-01

Written by two experts in the field, this book is ideal for advanced undergraduate students, graduate students, and researchers in all fields of science. It is self-contained: it contains the basic requirements from mathematics, probability theory, statistics, information theory, and computer

An introduction to tensor calculus, relativity and cosmology /3rd edition/

Science.gov (United States)

Lawden, D. F.

This textbook introduction to the principles of special relativity proceeds within the context of cartesian tensors. Newton's laws of motion are reviewed, as are the Lorentz transformations, Minkowski space-time, and the Fitzgerald contraction. Orthogonal transformations are described, and invariants, gradients, tensor derivatives, contraction, scalar products, divergence, pseudotensors, vector products, and curl are defined. Special relativity mechanics are explored in terms of mass, momentum, the force vector, the Lorentz transformation equations for force, calculations for photons and neutrinos, the development of the Lagrange and Hamilton equations, and the energy-momentum tensor. Electrodynamics is investigated, together with general tensor calculus and Riemmanian space. The General Theory of Relativity is presented, along with applications to astrophysical phenomena such as black holes and gravitational waves. Finally, analytical discussions of cosmological problems are reviewed, particularly Einstein, de Sitter, and Friedmann universes, redshifts, event horizons, and the redshift.

Proceedings of the 3rd Workshop of R and D and technologies on Radioactive Waste management. Vol. 1,2

International Nuclear Information System (INIS)

1998-01-01

The sessions present at the 3rd workshops on radioactive waste management are: 1. Bases for the radioactive waste management 2. Capsule fuel barrier 3. Barriers for engineering 4. Geologic barriers 5. The biosphere as barrier

Country Nuclear Power Profiles - 2013 Edition

International Nuclear Information System (INIS)

2013-08-01

The Country Nuclear Power Profiles compile background information on the status and development of nuclear power programmes in Member States. The CNPP summarizes organizational and industrial aspects of nuclear power programs and provides information about the relevant legislative, regulatory, and international framework in each country. Its descriptive and statistical overview of the overall economic, energy, and electricity situation in each country and its nuclear power framework is intended to serve as an integrated source of key background information about nuclear power programs in the world. This 2013 edition, issued on CD-ROM and Web pages, contains updated country information for 51 countries

Ebola virus RNA editing depends on the primary editing site sequence and an upstream secondary structure.

Directory of Open Access Journals (Sweden)

Masfique Mehedi

Full Text Available Ebolavirus (EBOV, the causative agent of a severe hemorrhagic fever and a biosafety level 4 pathogen, increases its genome coding capacity by producing multiple transcripts encoding for structural and nonstructural glycoproteins from a single gene. This is achieved through RNA editing, during which non-template adenosine residues are incorporated into the EBOV mRNAs at an editing site encoding for 7 adenosine residues. However, the mechanism of EBOV RNA editing is currently not understood. In this study, we report for the first time that minigenomes containing the glycoprotein gene editing site can undergo RNA editing, thereby eliminating the requirement for a biosafety level 4 laboratory to study EBOV RNA editing. Using a newly developed dual-reporter minigenome, we have characterized the mechanism of EBOV RNA editing, and have identified cis-acting sequences that are required for editing, located between 9 nt upstream and 9 nt downstream of the editing site. Moreover, we show that a secondary structure in the upstream cis-acting sequence plays an important role in RNA editing. EBOV RNA editing is glycoprotein gene-specific, as a stretch encoding for 7 adenosine residues located in the viral polymerase gene did not serve as an editing site, most likely due to an absence of the necessary cis-acting sequences. Finally, the EBOV protein VP30 was identified as a trans-acting factor for RNA editing, constituting a novel function for this protein. Overall, our results provide novel insights into the RNA editing mechanism of EBOV, further understanding of which might result in novel intervention strategies against this viral pathogen.

Ebola virus RNA editing depends on the primary editing site sequence and an upstream secondary structure.

Science.gov (United States)

Mehedi, Masfique; Hoenen, Thomas; Robertson, Shelly; Ricklefs, Stacy; Dolan, Michael A; Taylor, Travis; Falzarano, Darryl; Ebihara, Hideki; Porcella, Stephen F; Feldmann, Heinz

2013-01-01

Ebolavirus (EBOV), the causative agent of a severe hemorrhagic fever and a biosafety level 4 pathogen, increases its genome coding capacity by producing multiple transcripts encoding for structural and nonstructural glycoproteins from a single gene. This is achieved through RNA editing, during which non-template adenosine residues are incorporated into the EBOV mRNAs at an editing site encoding for 7 adenosine residues. However, the mechanism of EBOV RNA editing is currently not understood. In this study, we report for the first time that minigenomes containing the glycoprotein gene editing site can undergo RNA editing, thereby eliminating the requirement for a biosafety level 4 laboratory to study EBOV RNA editing. Using a newly developed dual-reporter minigenome, we have characterized the mechanism of EBOV RNA editing, and have identified cis-acting sequences that are required for editing, located between 9 nt upstream and 9 nt downstream of the editing site. Moreover, we show that a secondary structure in the upstream cis-acting sequence plays an important role in RNA editing. EBOV RNA editing is glycoprotein gene-specific, as a stretch encoding for 7 adenosine residues located in the viral polymerase gene did not serve as an editing site, most likely due to an absence of the necessary cis-acting sequences. Finally, the EBOV protein VP30 was identified as a trans-acting factor for RNA editing, constituting a novel function for this protein. Overall, our results provide novel insights into the RNA editing mechanism of EBOV, further understanding of which might result in novel intervention strategies against this viral pathogen.

Understanding Editing Behaviors in Multilingual Wikipedia.

Science.gov (United States)

Kim, Suin; Park, Sungjoon; Hale, Scott A; Kim, Sooyoung; Byun, Jeongmin; Oh, Alice H

2016-01-01

Multilingualism is common offline, but we have a more limited understanding of the ways multilingualism is displayed online and the roles that multilinguals play in the spread of content between speakers of different languages. We take a computational approach to studying multilingualism using one of the largest user-generated content platforms, Wikipedia. We study multilingualism by collecting and analyzing a large dataset of the content written by multilingual editors of the English, German, and Spanish editions of Wikipedia. This dataset contains over two million paragraphs edited by over 15,000 multilingual users from July 8 to August 9, 2013. We analyze these multilingual editors in terms of their engagement, interests, and language proficiency in their primary and non-primary (secondary) languages and find that the English edition of Wikipedia displays different dynamics from the Spanish and German editions. Users primarily editing the Spanish and German editions make more complex edits than users who edit these editions as a second language. In contrast, users editing the English edition as a second language make edits that are just as complex as the edits by users who primarily edit the English edition. In this way, English serves a special role bringing together content written by multilinguals from many language editions. Nonetheless, language remains a formidable hurdle to the spread of content: we find evidence for a complexity barrier whereby editors are less likely to edit complex content in a second language. In addition, we find that multilinguals are less engaged and show lower levels of language proficiency in their second languages. We also examine the topical interests of multilingual editors and find that there is no significant difference between primary and non-primary editors in each language.

Understanding Editing Behaviors in Multilingual Wikipedia.

Directory of Open Access Journals (Sweden)

Suin Kim

Full Text Available Multilingualism is common offline, but we have a more limited understanding of the ways multilingualism is displayed online and the roles that multilinguals play in the spread of content between speakers of different languages. We take a computational approach to studying multilingualism using one of the largest user-generated content platforms, Wikipedia. We study multilingualism by collecting and analyzing a large dataset of the content written by multilingual editors of the English, German, and Spanish editions of Wikipedia. This dataset contains over two million paragraphs edited by over 15,000 multilingual users from July 8 to August 9, 2013. We analyze these multilingual editors in terms of their engagement, interests, and language proficiency in their primary and non-primary (secondary languages and find that the English edition of Wikipedia displays different dynamics from the Spanish and German editions. Users primarily editing the Spanish and German editions make more complex edits than users who edit these editions as a second language. In contrast, users editing the English edition as a second language make edits that are just as complex as the edits by users who primarily edit the English edition. In this way, English serves a special role bringing together content written by multilinguals from many language editions. Nonetheless, language remains a formidable hurdle to the spread of content: we find evidence for a complexity barrier whereby editors are less likely to edit complex content in a second language. In addition, we find that multilinguals are less engaged and show lower levels of language proficiency in their second languages. We also examine the topical interests of multilingual editors and find that there is no significant difference between primary and non-primary editors in each language.

The 3rd International Conference on Mathematics, Science and Education 2016

International Nuclear Information System (INIS)

2017-01-01

The 3 rd International Conference of Mathematics, Science, and Education (ICMSE) 2016 on Semarang, 3-4 September 2016 organized by Faculty of Mathematics and Natural Science, Semarang State University. ICMSE2016 provides a platform to the researchers, experts and practitioners from academia, governments, NGOs, research institutes, and industries to meet and share cutting-edge progress in the fields of mathematics and natural science. It is reflected in this year theme “Contribution of Mathematics and Science Research for Sustainable Life in Facing Global Challenge”. The scope of this conference are Mathematics, Biology, Chemistry, and Physics,We thank to the keynote speakers and all authors of the contributed papers, for the cooperation rendered to us in the publication of the conference proceedings. In particular, we would like to place on record our thanks to the expert reviewers who have spared their time reviewing the papers. We also highly appreciate the assistance offered by many volunteers in the preparation of the conference proceedings, and of course to the sponsors assisting in funding this conference, especially Research, Technology and Higher Education Ministry of Indonesia for supporting this conference.The committee selected 71 papers from 129 papers presented in this forum to be published in Journal of Physics: Conference Series (Institute of Physics Publisher) indexed by Scopus. We hope that this program will further stimulate research in Mathematics, Science, and Education; share research interest and information; and create a forum of collaboration and build trust relationship. We feel honored and privileged to serve the best recent developments in the field of Mathematics and Science Education to you through this exciting program.Chairperson,Dr. Margareta RahayuningsihCOMMITTEEInternational Scientific Advisory BoardEdy Cahyono ( Chemistry Department, State University of Semarang )Rahim Sahar ( Department of Physics, Universiti Teknologi

An R&D Management Framework for Eco-Technology

Directory of Open Access Journals (Sweden)

Kenji Sano

2011-08-01

Full Text Available Although research and development (R&D affects new value-added creation, including that related to environmental aspects, there is little literature dealing with the integration of R&D management and eco-value. Here, eco-value of technology is defined as the advantage of environmental competitiveness in the market. This paper proposes a framework of R&D management of eco-technology (RDMOET, consisting of: (1 future research for sustainability; (2 making an original eco-theme portfolio and roadmap; (3 gap analysis and implementation of new eco-themes; and (4 eco-value evaluation. (1 and (4 are new processes compared with conventional R&D management. Through practice at the Corporate R&D Center of Toshiba Corporation, the usefulness of the proposed framework is verified from the viewpoint of not only technological eco-innovation, but also that of organizational learning for environmental sustainability.

3rd international KES conference on Smart Education and Smart e-Learning

CERN Document Server

Howlett, Robert; Jain, Lakhmi

2016-01-01

This book contains the contributions presented at the 3rd international KES conference on Smart Education and Smart e-Learning, which took place in Puerto de la Cruz, Tenerife, Spain, June 15-17, 2016. It contains a total of 56 peer-reviewed book chapters that are grouped into several parts: Part 1 - Smart University: Conceptual Modeling, Part 2 – Smart Education: Research and Case Studies, Part 3 – Smart e-Learning, Part 4 – Smart Education: Software and Hardware Systems, and Part 5 – Smart Technology as a Resource to Improve Education and Professional Training. We believe that the book will serve as a useful source of research data and valuable information for faculty, scholars, Ph.D. students, administrators, and practitioners - those who are interested in innovative areas of smart education and smart e-learning. .

Prospects for Russian Military R&D.

Science.gov (United States)

1996-01-01

conflicts with a self-defeating desire to close the West out, fueled by nationalistic re- sentment of Russia’s underdog position and a distinctly Cold War...increasingly inte- grated. Until Russia succeeds in creating its brand of market econ- omy and achieves widespread economic prosperity, a process that could...defense spending in 1996 would focus on " brand new weapons and equipment" and that spending for defense R&D programs would remain at this year’s

R&D ERL: Beam dynamics, parameters, and physics to be learned

Energy Technology Data Exchange (ETDEWEB)

Kayran, D.

2010-02-01

The R&D ERL facility at BNL aims to demonstrate CW operation of ERL with average beam current in the range of 0.1-1 ampere, combined with very high efficiency of energy recovery. The ERL is being installed in one of the spacious bays in Bldg. 912 of the RHIC/AGS complex (Fig. 1). The bay is equipped with an overhead crane. The facility has a control room, two service rooms and a shielded ERL cave. The control room is located outside of the bay in a separate building. The single story house is used for a high voltage power supply for 1 MW klystron. The two-story unit houses a laser room, the CW 1 MW klystron with its accessories, most of the power supplies and electronics. The ERL R&D program has been started by the Collider Accelerator Department (C-AD) at BNL as an important stepping-stone for 10-fold increase of the luminosity of the Relativistic Heavy Ion Collider (RHIC) using relativistic electron cooling of gold ion beams with energy of 100 GeV per nucleon. Furthermore, the ERL R&D program extends toward a possibility of using 10-20 GeV ERL for future electron-hadron/heavy ion collider, MeRHIC/eRHIC. These projects are the driving force behind the development of ampere-class ERL technology, which will find many applications including light sources and FELs. The intensive R&D program geared towards the construction of the prototype ERL is under way: from development of high efficiency photo-cathodes to the development of new merging system compatible with emittance compensation.

The 3rd colloquium on process simulation. Proceedings

Energy Technology Data Exchange (ETDEWEB)

Jokilaakso, A. [ed.

1996-12-31

The presentations collected in this volume were presented at the 3rd Colloquium on Process Simulation held at Helsinki University of Technology, Espoo, Finland, June 12-14, 1996. In the more developed industrial nations, the processes for producing chemicals, energy, and materials encounter environmental concern and laws which challenge engineers to develop the processes towards more efficient, economical and safe operation. This necessitates more thorough understanding of the processes and phenomena involved. Formerly, the development of the processes was largely based on trial and error, whereas today, the development of computer performance together with the diversification of modelling software enables simulation of the processes. The increased capacity and possibilities for modelling the processes brought by the improved hardware and software, have generated a strong demand for more accurate mathematical descriptions of the processes. Especially, the coupling of computational fluid dynamics and chemical kinetics, combustion, and thermodynamics is of current interest in process oriented technology. This colloquium attempts to give examples of modelling efforts in operation in different universities, research institutes and companies. Furthermore, the aim of this colloquium is to offer an annual opportunity to the researchers to come together and discuss their common problems and the state of their investigations

The 3rd colloquium on process simulation. Proceedings

Energy Technology Data Exchange (ETDEWEB)

Jokilaakso, A [ed.

1997-12-31

The presentations collected in this volume were presented at the 3rd Colloquium on Process Simulation held at Helsinki University of Technology, Espoo, Finland, June 12-14, 1996. In the more developed industrial nations, the processes for producing chemicals, energy, and materials encounter environmental concern and laws which challenge engineers to develop the processes towards more efficient, economical and safe operation. This necessitates more thorough understanding of the processes and phenomena involved. Formerly, the development of the processes was largely based on trial and error, whereas today, the development of computer performance together with the diversification of modelling software enables simulation of the processes. The increased capacity and possibilities for modelling the processes brought by the improved hardware and software, have generated a strong demand for more accurate mathematical descriptions of the processes. Especially, the coupling of computational fluid dynamics and chemical kinetics, combustion, and thermodynamics is of current interest in process oriented technology. This colloquium attempts to give examples of modelling efforts in operation in different universities, research institutes and companies. Furthermore, the aim of this colloquium is to offer an annual opportunity to the researchers to come together and discuss their common problems and the state of their investigations

CONTEMPT 4/MOD 3: a multicompartment containment system analysis program

International Nuclear Information System (INIS)

Cheng, T.C.; Metcalfe, L.J.; Hartman, J.E.; Mings, W.J.; Crail, A.C.

1982-12-01

CONTEMPT4/MOD3 is a digital computer program, written in FORTRAN IV, that describes the behavior of multicompartment pressurized water reactor (PWR) containment systems and experimental containment systems subjected to postulated loss-of-coolant accident (LOCA) conditons. The program calculates the time variation of compartment pressures, temperatures, mass and energy inventories, heat structure temperature distributions, and intercompartment mass and energy exchange based on user-supplied values for compartment descriptions, time step and edit controls, and selected problem features. Analytical models available to describe containment systems include models for containment fans and pumps, cooling sprays, fan coolers, heat-conducting structures, sump drains, and PWR ice condensers. Dynamic stroage allocation (DSA) is used to limit the amount of computer core used for each problem. Optional automatic time step control allows the code to determine time step sizes within limits dictated by the user. Multicompartment capability (up to 999 individual compartments) and generalized, user-oriented input-data descriptions permit improved flexibility over previous codes in the CONTEMPT series. Analytical model descriptions, input instructions, and sample problem results are presented

The Perception of Entrepreneurial and 3rd Generation University in Turkey

Directory of Open Access Journals (Sweden)

Deniz Zungun

2016-07-01

Full Text Available Increased competition caused by globalization has led to philosophical changes in private and public businesses. This situation has affected educational institutions and they have needed dynamic, innovator and transformational tools in order to survive in competitive environment. The universities defined as �3rd Generation Universities� need commercialization, network among universities, close co-operation among institutions and entrepreneurship as well as intellectual and innovative changes. In this regard, the aim of the research is formed by the analysis of �Entrepreneur University� concept from the perspective of the academicians that served at managerial positions at the universities in Turkey. The research is limited to the opinions of the academicians that served at top, middle and lower management at randomly chosen 20 universities.

Idaho National Laboratory Quarterly Occurrence Analysis - 3rd Quarter FY-2016

Energy Technology Data Exchange (ETDEWEB)

Mitchell, Lisbeth Ann [Idaho National Lab. (INL), Idaho Falls, ID (United States)

2016-09-01

This report is published quarterly by the Idaho National Laboratory (INL) Quality and Performance Management Organization. The Department of Energy (DOE) Occurrence Reporting and Processing System (ORPS), as prescribed in DOE Order 232.2, “Occurrence Reporting and Processing of Operations Information,” requires a quarterly analysis of events, both reportable and not reportable, for the previous 12 months. This report is the analysis of 73 reportable events (23 from the 3rd Qtr FY-16 and 50 from the prior three reporting quarters), as well as 45 other issue reports (including events found to be not reportable and Significant Category A and B conditions) identified at INL during the past 12 months (16 from this quarter and 29 from the prior three quarters).

Constancy and Variability: Dialogic Literacy Events as Sites for Improvisation in Two 3rd-Grade Classrooms

Science.gov (United States)

Jordan, Michelle E.; Santori, Diane

2015-01-01

This multisite study investigates dialogic literacy events that revolved around narrative and informational texts in two 3rd-grade classrooms. The authors offer a metaphor of musical improvisation to contemplate dialogic literacy events as part of the repertoire of teaching and learning experiences. In literacy learning, where there is much…

Internationalisation of R&D

DEFF Research Database (Denmark)

Haakonsson, Stine Jessen; Ujjual, Vandana

2015-01-01

study of a global firm from the most globalised industry in terms of R&D, biotechnology. The article investigates dynamics of internationalisation of R&D in global networks by looking at: 1) the strategic drivers of location, either as a large potential market or as a pool of competencies; and 2......) the evolution of the company and its R&D activities into emerging market locations: India, China and Brazil. Together, these two dimensions constitute the drivers of R&D internationalisation and contribute to the construction of global innovation networks through knowledge augmenting and exploiting strategies....... The article shows how multinational enterprises can use a combination of augmenting and exploiting strategies in emerging markets and hence demonstrates that international R&D activities not always evolve in a sequential and ordered trajectory....

MRB3010 is a core component of the MRB1 complex that facilitates an early step of the kinetoplastid RNA editing process

Czech Academy of Sciences Publication Activity Database

Ammerman, M. L.; Hashimi, Hassan; Novotná, Lucie; Číčová, Zdeňka; Mcevoy, S. M.; Lukeš, Julius; Read, L. K.

2011-01-01

Roč. 17, č. 5 (2011), 865-877 ISSN 1355-8382 R&D Projects: GA ČR GA204/09/1667; GA MŠk 2B06129; GA MŠk LC07032 Institutional research plan: CEZ:AV0Z60220518 Keywords : RNA editing * trypanosome * MRB1 complex * mitochondria * kinetoplast Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 5.095, year: 2011

TbRGG2 facilitates kinetoplastid RNA editing initiation and progression past intrinsic pause sites.

Science.gov (United States)

Ammerman, Michelle L; Presnyak, Vladimir; Fisk, John C; Foda, Bardees M; Read, Laurie K

2010-11-01

TbRGG2 is an essential kinetoplastid RNA editing accessory factor that acts specifically on pan-edited RNAs. To understand the mechanism of TbRGG2 action, we undertook an in-depth analysis of edited RNA populations in TbRGG2 knockdown cells and an in vitro examination of the biochemical activities of the protein. We demonstrate that TbRGG2 down-regulation more severely impacts editing at the 5' ends of pan-edited RNAs than at their 3' ends. The initiation of editing is reduced to some extent in TbRGG2 knockdown cells. In addition, TbRGG2 plays a post-initiation role as editing becomes stalled in TbRGG2-depleted cells, resulting in an overall decrease in the 3' to 5' progression of editing. Detailed analyses of edited RNAs from wild-type and TbRGG2-depleted cells reveal that TbRGG2 facilitates progression of editing past intrinsic pause sites that often correspond to the 3' ends of cognate guide RNAs (gRNAs). In addition, noncanonically edited junction regions are either absent or significantly shortened in TbRGG2-depleted cells, consistent with impaired gRNA transitions. Sequence analysis further suggests that TbRGG2 facilitates complete utilization of certain gRNAs. In vitro RNA annealing and in vivo RNA unwinding assays demonstrate that TbRGG2 can modulate RNA-RNA interactions. Collectively, these data are consistent with a model in which TbRGG2 facilitates initiation and 3' to 5' progression of editing through its ability to affect gRNA utilization, both during the transition between specific gRNAs and during usage of certain gRNAs.

FOREWORD: 3rd International Workshop on New Computational Methods for Inverse Problems (NCMIP 2013)

Science.gov (United States)

Blanc-Féraud, Laure; Joubert, Pierre-Yves

2013-10-01

Conference logo This volume of Journal of Physics: Conference Series is dedicated to the scientific contributions presented during the 3rd International Workshop on New Computational Methods for Inverse Problems, NCMIP 2013 (http://www.farman.ens-cachan.fr/NCMIP_2013.html). This workshop took place at Ecole Normale Supérieure de Cachan, in Cachan, France, on 22 May 2013, at the initiative of Institut Farman. The prior editions of NCMIP also took place in Cachan, France, firstly within the scope of the ValueTools Conference, in May 2011 (http://www.ncmip.org/2011/), and secondly at the initiative of Institut Farman, in May 2012 (http://www.farman.ens-cachan.fr/NCMIP_2012.html). The NCMIP Workshop focused on recent advances in the resolution of inverse problems. Indeed inverse problems appear in numerous scientific areas such as geophysics, biological and medical imaging, material and structure characterization, electrical, mechanical and civil engineering, and finances. The resolution of inverse problems consists of estimating the parameters of the observed system or structure from data collected by an instrumental sensing or imaging device. Its success firstly requires the collection of relevant observation data. It also requires accurate models describing the physical interactions between the instrumental device and the observed system, as well as the intrinsic properties of the solution itself. Finally, it requires the design of robust, accurate and efficient inversion algorithms. Advanced sensor arrays and imaging devices provide high rate and high volume data; in this context, the efficient resolution of the inverse problem requires the joint development of new models and inversion methods, taking computational and implementation aspects into account. During this one-day workshop, researchers had the opportunity to bring to light and share new techniques and results in the field of inverse problems. The topics of the workshop were: algorithms and computational

CERES BiDirectional Scans (BDS) data in HDF (CER_BDS_TRMM-PFM_Edition1)

Science.gov (United States)

Wielicki, Bruce A. (Principal Investigator)

Each BiDirectional Scans (BDS) data product contains twenty-four hours of Level-1b data for each CERES scanner instrument mounted on each spacecraft. The BDS includes samples taken in normal and short Earth scan elevation profiles in both fixed and rotating azimuth scan modes (including space, internal calibration, and solar calibration views). The BDS contains Level-0 raw (unconverted) science and instrument data as well as the geolocated converted science and instrument data. The BDS contains additional data not found in the Level-0 input file, including converted satellite position and velocity data, celestial data, converted digital status data, and parameters used in the radiance count conversion equations. The following CERES BDS data sets are currently available: CER_BDS_TRMM-PFM_Edition1 CER_BDS_Terra-FM1_Edition1 CER_BDS_Terra-FM2_Edition1 CER_BDS_Terra-FM1_Edition2 CER_BDS_Terra-FM2_Edition2 CER_BDS_Aqua-FM3_Edition1 CER_BDS_Aqua-FM4_Edition1 CER_BDS_Aqua-FM3_Edition2 CER_BDS_Aqua-FM4_Edition2 CER_BDS_Aqua-FM3_Edition1-CV CER_BDS_Aqua-FM4_Edition1-CV CER_BDS_Terra-FM1_Edition1-CV CER_BDS_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2000-12-31] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

Domestic R&D and Offshoring

DEFF Research Database (Denmark)

Junge, Martin; Sørensen, Anders

2017-01-01

survey and register data. No evidence is found for a lower probability of own R&D after offshoring takes place compared to before. Moreover, offshoring does not lead to lower R&D intensity in general. However, firms that offshore R&D activity have larger R&D intensity after offshoring has taken place...

3rd International Symposium for Intelligent Transportation and Smart City

CERN Document Server

Xie, Xiongyao; Sun, Jian; Ma, Limin; Chen, Yinong; ITASC

2017-01-01

This book presents research advances in intelligent transportation and smart cities in detail, mainly focusing on green traffic and urban utility tunnels, presented at the 3rd International Symposium for Intelligent Transportation and Smart City (ITASC) held at Tongji University, Shanghai, on May 19–20, 2017. It discusses a number of hot topics, such as the 2BMW system (Bus, Bike, Metro and Walking), transportation safety and environmental protection, urban utility design and application, as well as the application of BIM (Building Information Modeling) in city design. By connecting the theory and applications of intelligent transportation in smart cities, it enhances traffic efficiency and quality. The book gathers numerous selected papers and lectures, including contributions from respected scholars and the latest engineering advances, to provide guidance to researchers in the field of transportation and urban planning at universities and in related industries. The first conference in the ITASC series sta...

3rd grade English language learners making sense of sound

Science.gov (United States)

Suarez, Enrique; Otero, Valerie

2013-01-01

Despite the extensive body of research that supports scientific inquiry and argumentation as cornerstones of physics learning, these strategies continue to be virtually absent in most classrooms, especially those that involve students who are learning English as a second language. This study presents results from an investigation of 3rd grade students' discourse about how length and tension affect the sound produced by a string. These students came from a variety of language backgrounds, and all were learning English as a second language. Our results demonstrate varying levels, and uses, of experiential, imaginative, and mechanistic reasoning strategies. Using specific examples from students' discourse, we will demonstrate some of the productive aspects of working within multiple language frameworks for making sense of physics. Conjectures will be made about how to utilize physics as a context for English Language Learners to further conceptual understanding, while developing their competence in the English language.

Soil Microbiology, Ecology, and Biochemistry

Science.gov (United States)

The 4th edition of Soil Microbiology, Ecology, and Biochemistry Edited by Eldor Paul continues in the vein of the 3rd edition by providing an excellent, broad-reaching introduction to soil biology. The new edition improves on the previous by providing extensive supplementary materials, links to outs...

GPU Computing Gems Emerald Edition

CERN Document Server

Hwu, Wen-mei W

2011-01-01

".the perfect companion to Programming Massively Parallel Processors by Hwu & Kirk." -Nicolas Pinto, Research Scientist at Harvard & MIT, NVIDIA Fellow 2009-2010 Graphics processing units (GPUs) can do much more than render graphics. Scientists and researchers increasingly look to GPUs to improve the efficiency and performance of computationally-intensive experiments across a range of disciplines. GPU Computing Gems: Emerald Edition brings their techniques to you, showcasing GPU-based solutions including: Black hole simulations with CUDA GPU-accelerated computation and interactive display of

REDIdb: the RNA editing database.

Science.gov (United States)

Picardi, Ernesto; Regina, Teresa Maria Rosaria; Brennicke, Axel; Quagliariello, Carla

2007-01-01

The RNA Editing Database (REDIdb) is an interactive, web-based database created and designed with the aim to allocate RNA editing events such as substitutions, insertions and deletions occurring in a wide range of organisms. The database contains both fully and partially sequenced DNA molecules for which editing information is available either by experimental inspection (in vitro) or by computational detection (in silico). Each record of REDIdb is organized in a specific flat-file containing a description of the main characteristics of the entry, a feature table with the editing events and related details and a sequence zone with both the genomic sequence and the corresponding edited transcript. REDIdb is a relational database in which the browsing and identification of editing sites has been simplified by means of two facilities to either graphically display genomic or cDNA sequences or to show the corresponding alignment. In both cases, all editing sites are highlighted in colour and their relative positions are detailed by mousing over. New editing positions can be directly submitted to REDIdb after a user-specific registration to obtain authorized secure access. This first version of REDIdb database stores 9964 editing events and can be freely queried at http://biologia.unical.it/py_script/search.html.

33{sup rd} international Vienna motor symposium. Vol. 2. Second day; 33. internationales Wiener Motorensymposium. Bd. 2. Zweiter Tag

Energy Technology Data Exchange (ETDEWEB)

Lenz, Hans Peter (comp.)

2012-11-01

This two-volume report makes the presentations of the 33{sup rd} International Vienna Motor Symposium (April 26-27, 2012) available to a wider audience. The objective of the Vienna Motor Symposia is to examine current topics of particular interest. Among others, the work examines the above mentioned topics. Included is a CD-ROM containing the presentations in their original form and in English translation. Edited by Univ.-Prof. Dr. techn. Dipl.-Ing. H.P. Lenz, VDI, Chairman of the OeVK (Austrian Society of Automotive Engineers, Vienna).

33{sup rd} international Vienna motor symposium. Vol. 1. First day; 33. internationales Wiener Motorensymposium. Bd. 1. Erster Tag

Energy Technology Data Exchange (ETDEWEB)

Lenz, Hans Peter (comp.)

2012-11-01

This two-volume report makes the presentations of the 33{sup rd} International Vienna Motor Symposium (April 26-27, 2012) available to a wider audience. The objective of the Vienna Motor Symposia is to examine current topics of particular interest. Among others, the work examines the above mentioned topics. Included is a CD-ROM containing the presentations in their original form and in English translation. Edited by Univ.-Prof. Dr. techn. Dipl.-Ing. H.P. Lenz, VDI, Chairman of the OeVK (Austrian Society of Automotive Engineers, Vienna).

[Proceedings of the] International Conference on Educational Data Mining (EDM) (3rd, Pittsburgh, PA, July 11-13, 2010)

Science.gov (United States)

Baker, Ryan S. J. d., Ed.; Merceron, Agathe, Ed.; Pavlik, Philip I., Jr., Ed.

2010-01-01

The Third International Conference on Data Mining (EDM 2010) was held in Pittsburgh, PA, USA. It follows the second conference at the University of Cordoba, Spain, on July 1-3, 2009 and the first edition of the conference held in Montreal in 2008, and a series of workshops within the AAAI, AIED, EC-TEL, ICALT, ITS, and UM conferences. EDM 2011…

A distant cis acting intronic element induces site-selective RNA editing

DEFF Research Database (Denmark)

Daniel, Chammiran; Venø, Morten Trillingsgaard; Ekdahl, Ylva

2012-01-01

Transcripts have been found to be site selectively edited from adenosine-to-inosine (A-to-I) in the mammalian brain, mostly in genes involved in neurotransmission. While A-to-I editing occurs at double-stranded structures, other structural requirements are largely unknown. We have investigated...... shown to be important for A-to-I editing. We demonstrate that the element also can induce editing in related but normally not edited RNA sequences. In human, thousands of genes are edited in duplexes formed by inverted repeats in non-coding regions. It is likely that numerous such duplexes can induce...... the requirements for editing at the I/M site in the Gabra-3 transcript of the GABA(A) receptor. We identify an evolutionarily conserved intronic duplex, 150 nt downstream of the exonic hairpin where the I/M site resides, which is required for its editing. This is the first time a distant RNA structure has been...

ChemSession'06 - 3{sup rd} Seminary of Warsaw PhD Students in Chemistry. Abstracts

Energy Technology Data Exchange (ETDEWEB)

Zachara, J; Lulinski, S [Warsaw University of Technology, Warsaw (Poland); Dobrowolski, J C [Industrial Chemistry Research Institute, Warsaw (Poland); National Institute of Drugs, Warsaw (Poland); Raczynska, E D [Warsaw University of Life Sciences (SGGW), Warsaw (Poland); Fuks, L [Institute of Nuclear Chemistry and Technology, Warsaw (Poland); Cyranski, M K; Stepien, B T [University of Warsaw, Warsaw (Poland); Sawicki, M G [Cecylia Plater-Zylberkowna High School, Warsaw (Poland)

2006-07-01

3{sup rd} Annual Seminary of Warsaw PhD Students in Chemistry presented the latest achievements in chemistry, obtained in all Warsaw universities and scientific institutes. In 2006 participants presented 4 plenary lectures, and 109 posters. Among others, posters covered four disciplines related to the nuclear sciences: (a) radiobiology and radiotherapy, (b) radiation chemistry and photochemistry, (c) isotopic effects in chemistry, and (d) chemical technology.

FY97 Geothermal R&D Program Plan

Energy Technology Data Exchange (ETDEWEB)

None

1996-09-01

This is the Sandia National Laboratories Geothermal program plan. This is a DOE Geothermal Program planning and control document. Many of these reports were issued only in draft form. This one is of special interest for historical work because it contains what seems to be a complete list of Sandia geothermal program publications (citations / references) from about 1975 to late 1996. (DJE 2005)

Windows and Envelope R&D Opportunities Workshop

Energy Technology Data Exchange (ETDEWEB)

Building Technologies Office

2018-02-01

BTO's Emerging Technologies program held a two-day workshop on “Windows and Envelope R&D Opportunities” on May 31 and June 1, 2017 at the Illinois Institute of Technology in Chicago, Illinois. A broad range of about 100 experts from industry, academia, national laboratories, and government participated, contributing their ideas, insights, and perspectives. Their feedback is intended to help inform and augment BTO’s research and development activities.

R&D INVESTMENTS AND SPILLOVERS UNDER ENDOGENOUS ABSORPTIVE CAPACITY: COMPETITIVE R&D CANNOT TAKE FULL-ADVANTAGE OF COMPLEMENTARITY IN ABSORPTIVE CAPACITY WHILE COOPERATIVE R&D CAN

Directory of Open Access Journals (Sweden)

Mário A.P.M. Da Silva

2018-03-01

Full Text Available We show that the setting up of general conditions on complementarity in absorptive capacity gives rise to different, if not opposite Nash equilibrium outcomes to those found when absorptive capacity is assumed to be determined only by the similarity of R&D orientations. Firms that cooperate in R&D can take full-advantage of complementarity in R&D by adopting firm-specific R&D paths, which appears to contradict findings and predictions of existing theoretical literature on R&D and spillovers. Oddly, firms competing in R&D cannot gain the most from the potential of complementarity in knowledge by not choosing firm-specific R&D approaches in equilibrium under even milder conditions, which is contrary to another prediction of existing related models.

3rd International Conference on Modelling and Management of Engineering Processes

CERN Document Server

Gericke, Kilian; Szélig, Nikoletta; Vajna, Sándor

2015-01-01

Innovative processes for the development of products and services are more and more considered as an organisational capability, which is recognised to be increasingly important for business success in today’s competitive environment. However, management and academia need a more profound understanding of these processes in order to develop improved management approaches to exploit business potentials. This book contains the proceedings of the 3rd International Conference on Modelling and Management of Engineering Processes (MMEP2013) held in Magdeburg, Germany, in November 2013. It includes contributions from international leading researchers in the fields of process modelling and process management. The conference topics were recent trends in modelling and management of engineering processes, potential synergies between different modelling approaches, future challenges for the management of engineering processes as well as future research in these areas.

R&D Challenges for SFR Design and Safety Analysis – Opportunities for International Cooperations

International Nuclear Information System (INIS)

Devictor, Nicolas

2013-01-01

Examples of R&D challenges related to safety have been presented. For any domain, R&D activities includes modelling, codes development and their V&V process, with the support of experimental programs. The success in the R&D will help the safety case and the acceptability of SFR. Some of these activities are relevant for international cooperation especially benchmarks and sharing of experimental facilities. This last point could take benefit of recent catalogues experimental facilities (already operational or in project), for example from the TAREF Task Force of OECD/NEA and the European project ADRIANA

3rd harmonic electron cyclotron resonant heating absorption enhancement by 2nd harmonic heating at the same frequency in a tokamak

International Nuclear Information System (INIS)

Gnesin, S; Coda, S; Goodman, T P; Decker, J; Peysson, Y; Mazon, D

2012-01-01

The fundamental mechanisms responsible for the interplay and synergy between the absorption dynamics of extraordinary-mode electron cyclotron waves at two different harmonic resonances (the 2nd and 3rd) are investigated in the TCV tokamak. An enhanced 3rd harmonic absorption in the presence of suprathermal electrons generated by 2nd harmonic heating is predicted by Fokker–Planck simulations, subject to complex alignment requirements in both physical space and momentum space. The experimental signature for the 2nd/3rd harmonic synergy is sought through the suprathermal bremsstrahlung emission in the hard x-ray range of photon energy. Using a synthetic diagnostic, the emission variation due to synergy is calculated as a function of the injected power and of the radial transport of suprathermal electrons. It is concluded that in the present experimental setup a synergy signature has not been unambiguously detected. The detectability of the synergy is then discussed with respect to variations and uncertainties in the plasma density and effective charge in view of future optimized experiments. (paper)

Results of the 3rd Review Meeting of the Convention on Nuclear Safety and Preparatory Works for the 4th Meeting

International Nuclear Information System (INIS)

Choi, Young Sung; Choi, Kwang Sik; Kim, Woong Sik

2006-01-01

The 3 rd Review Meeting of the Convention on Nuclear Safety (CNS) took place from April 11-22, 2005. Fifty out of fifty-five Contracting Parties (CPs) participated with over 500 delegates in attendance. It was concluded that all CPs in attendance were in compliance with the requirements of the CNS. It was also noted that although the focus tends to be on the triennial national reports and review meetings, the CNS should emphasize an ongoing process that continually promotes the advancement of nuclear safety. With regard to this continuity process, the President of the 3 rd Review Meeting sent to all the CPs a message to remind of the lessons offered and learned from the Meeting and to put them into action as well. The president also asked that the CPs start in earnest later this year their preparations for the Forth Meeting in 2008. This paper introduces the results of the 3 rd Review Meeting and presents some suggestions on preparatory works that should be done for the next Review Meeting

Leadership Under Challenge: Information Technology R&D in a Competitive World. An Assessment of the Federal Networking and Information Technology R&D Program

National Research Council Canada - National Science Library

Marburger, John H; Kvamme, E. F; Scalise, George; Reed, Daniel A

2007-01-01

...).That leadership is essential to U.S. economic prosperity, security, and quality of life. This report presents a formal assessment of the Federal Networking and Information Technology R&D (NITRD...

3rd International Conference on Opto-Electronics and Applied Optics

CERN Document Server

Chakrabarti, Satyajit; Reehal, Haricharan; Lakshminarayanan, Vasudevan

2017-01-01

The Proceedings of 3rd International Conference on Opto-Electronics and Applied Optics, OPTRONIX 2016 is an effort to promote and present the research works by scientists and researchers including students in India and abroad in the area of Green Photonics and other related areas as well as to raise awareness about the recent trends of research and development in the area of the related fields. The book has been organized in such a way that it will be easier for the readers to go through and find out the topic of their interests. The first part includes the Keynote addresses by Rajesh Gupta, Department of Energy Science and Engineering, Indian Institute of Technology, Bombay; P.T. Ajith Kumar, President and Leading Scientist Light Logics Holography and Optics, Crescent Hill, Trivandrum, Kerala; and K.K. Ghosh, Institute of Engineering & Management, Kolkata, India.  The second part focuses on the Plenary and Invited Talks given by eminent scientists namely, Vasudevan Lakshminarayanan, University of Wate...

Managing Children's Services in the Public Library. Second Edition.

Science.gov (United States)

Fasick, Adele M.

This book examines the ways in which children's librarians can manage their services so collections and programs reach the intended audience. In the introduction to this second edition, the author considers recent changes in demographics, economics, social patterns, media and technology trends, and consequent changing emphases in managing…

Trends & Indicators: NE Universities Still R&D Powerhouses

Science.gov (United States)

Harney, John O.

2011-01-01

New England universities performed more than $4 billion worth of research and development (R&D) in 2009, but the region's share of total R&D performed by all U.S. universities remained at 7.3%, down from more than 10% in the 1980s. The region's university research labs have been world-famous for ideas that breed companies and whole…

CERES BiDirectional Scans (BDS) data in HDF (CER_BDS_Terra-FM1_Edition1)

Science.gov (United States)

Wielicki, Bruce A. (Principal Investigator)

Each BiDirectional Scans (BDS) data product contains twenty-four hours of Level-1b data for each CERES scanner instrument mounted on each spacecraft. The BDS includes samples taken in normal and short Earth scan elevation profiles in both fixed and rotating azimuth scan modes (including space, internal calibration, and solar calibration views). The BDS contains Level-0 raw (unconverted) science and instrument data as well as the geolocated converted science and instrument data. The BDS contains additional data not found in the Level-0 input file, including converted satellite position and velocity data, celestial data, converted digital status data, and parameters used in the radiance count conversion equations. The following CERES BDS data sets are currently available: CER_BDS_TRMM-PFM_Edition1 CER_BDS_Terra-FM1_Edition1 CER_BDS_Terra-FM2_Edition1 CER_BDS_Terra-FM1_Edition2 CER_BDS_Terra-FM2_Edition2 CER_BDS_Aqua-FM3_Edition1 CER_BDS_Aqua-FM4_Edition1 CER_BDS_Aqua-FM3_Edition2 CER_BDS_Aqua-FM4_Edition2 CER_BDS_Aqua-FM3_Edition1-CV CER_BDS_Aqua-FM4_Edition1-CV CER_BDS_Terra-FM1_Edition1-CV CER_BDS_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2005-11-02] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

CERES BiDirectional Scans (BDS) data in HDF (CER_BDS_Terra-FM2_Edition2)

Science.gov (United States)

Wielicki, Bruce A. (Principal Investigator)

Each BiDirectional Scans (BDS) data product contains twenty-four hours of Level-1b data for each CERES scanner instrument mounted on each spacecraft. The BDS includes samples taken in normal and short Earth scan elevation profiles in both fixed and rotating azimuth scan modes (including space, internal calibration, and solar calibration views). The BDS contains Level-0 raw (unconverted) science and instrument data as well as the geolocated converted science and instrument data. The BDS contains additional data not found in the Level-0 input file, including converted satellite position and velocity data, celestial data, converted digital status data, and parameters used in the radiance count conversion equations. The following CERES BDS data sets are currently available: CER_BDS_TRMM-PFM_Edition1 CER_BDS_Terra-FM1_Edition1 CER_BDS_Terra-FM2_Edition1 CER_BDS_Terra-FM1_Edition2 CER_BDS_Terra-FM2_Edition2 CER_BDS_Aqua-FM3_Edition1 CER_BDS_Aqua-FM4_Edition1 CER_BDS_Aqua-FM3_Edition2 CER_BDS_Aqua-FM4_Edition2 CER_BDS_Aqua-FM3_Edition1-CV CER_BDS_Aqua-FM4_Edition1-CV CER_BDS_Terra-FM1_Edition1-CV CER_BDS_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2006-01-01] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

CERES BiDirectional Scans (BDS) data in HDF (CER_BDS_Aqua-FM4_Edition1)

Science.gov (United States)

Wielicki, Bruce A. (Principal Investigator)

Each BiDirectional Scans (BDS) data product contains twenty-four hours of Level-1b data for each CERES scanner instrument mounted on each spacecraft. The BDS includes samples taken in normal and short Earth scan elevation profiles in both fixed and rotating azimuth scan modes (including space, internal calibration, and solar calibration views). The BDS contains Level-0 raw (unconverted) science and instrument data as well as the geolocated converted science and instrument data. The BDS contains additional data not found in the Level-0 input file, including converted satellite position and velocity data, celestial data, converted digital status data, and parameters used in the radiance count conversion equations. The following CERES BDS data sets are currently available: CER_BDS_TRMM-PFM_Edition1 CER_BDS_Terra-FM1_Edition1 CER_BDS_Terra-FM2_Edition1 CER_BDS_Terra-FM1_Edition2 CER_BDS_Terra-FM2_Edition2 CER_BDS_Aqua-FM3_Edition1 CER_BDS_Aqua-FM4_Edition1 CER_BDS_Aqua-FM3_Edition2 CER_BDS_Aqua-FM4_Edition2 CER_BDS_Aqua-FM3_Edition1-CV CER_BDS_Aqua-FM4_Edition1-CV CER_BDS_Terra-FM1_Edition1-CV CER_BDS_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2005-04-02] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

CERES BiDirectional Scans (BDS) data in HDF (CER_BDS_Aqua-FM4_Edition2)

Science.gov (United States)

Wielicki, Bruce A. (Principal Investigator)