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  1. Geolocator Data Reveal the Migration Route and Wintering Location of a Caribbean Martin (Progne dominicensis)

    NARCIS (Netherlands)

    Perlut, N.G.; Klak, T.C.; Rakhimberdiev, E.

    2017-01-01

    Caribbean Martins (Progne dominicensis)are common breeders on most Caribbean islands, where theyregularly roost and nest in urban areas from Februarythrough August. However, from September through January,the basic ecology of this species—its migration andwintering locations—are largely unknown. In

  2. Ceratocone: fatores prognósticos Keratoconus: prognosis factors

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    Rosana Molina Saraiva Elias

    2005-08-01

    Full Text Available OBJETIVO: Estudar pacientes portadores de ceratocone numa faixa etária menor do que a usual e tentar detectar algum fator que possa influenciar no prognóstico e na evolução da doença. MÉTODOS: Foram analisados pacientes menores de 15 anos, com diagnóstico de ceratocone. Todos se submeteram a um questionário, exame ocular e ceratoscopia computadorizada. Estes pacientes foram divididos em 3 grupos e submetidos a um teste com lente de contato: 1 um grupo em que foi possível a adaptação de lente de contato; 2 um grupo em que foi indicado o transplante penetrante de córnea; 3 um grupo em que foi indicada a correção com óculos. RESULTADOS: Pacientes com acuidade visual de 20/40 ou maior, geralmente não evoluíram para transplante no período estudado. Ao contrário, pacientes com visão de 20/60 ou menor, evoluíram para transplante penetrante mais rapidamente. Ao serem estudados casos em faixa etária menor (10-15 anos, 44% evoluíram para transplante. Observa-se que o ápice corneano tem localização muito variável, o que explica os diferentes níveis de dificuldade na adaptação de lentes de contato. Todos os pacientes com ápice deslocado superiormente e valores maiores que 66 D foram encaminhados para cirurgia, ao passo que olhos com valores menores que 66 D tiveram sucesso na adaptação. Nos olhos com ápice central, a adaptação foi mais fácil. Nos casos de ápice inferior não foi possível determinar um padrão para indicação de cirurgia. Nos olhos adaptados com lente de contato e curvatura menor que 51,10 D houve menos chance de evolução para transplante penetrante de córnea, quando comparados com pacientes de curvatura 57,60 ou maior. CONCLUSÃO: Pacientes com curvaturas maiores que 57,40, acuidade menor que 20/60 e com idade menor de 18 anos tem uma chance maior de evoluir para transplante de córnea. Quando o ápice do ceratocone é central a adaptação de lente de contato fica mais fácil.PURPOSE: To study

  3. Fatores prognósticos de letalidade na meningoencefalite tuberculosa Prognostic factors for tuberculous meningoencephalitis lethality

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    CEUCI NUNES

    1998-12-01

    Full Text Available Este é um estudo de prognóstico em que é avaliada uma coorte retrospectiva de 231 pacientes com diagnóstico de meningoencefalite tuberculosa, com o objetivo de determinar os fatores prognósticos de letalidade. A idade variou de menos de 1 a 68 anos, com 97 pacientes (42% na faixa etária igual ou inferior a 4 anos. Em 62 casos ocorreu a confirmação diagnóstica por líquor (cultura, baciloscopia, PCR ou necropsia; nos demais casos o diagnóstico foi baseado em critérios clínicos, epidemiológicos e resposta terapêutica. Na análise multivariada observamos que os fatores prognósticos mais importantes foram: faixa etária menor que 4 anos, ocorrência de convulsão e alterações de consciência consideradas graves.In order to describe the lethality predictors of patients with tuberculous meningoencephalitis, records of 231 patients were analysed. Ages ranged from less than 1 year to 68 years. Ninety-seven patients (42% were four years old or less. Apart from 73.2% of patients whose diagnosis was performed by clinical and epidemiologic criteria associated with response to specific therapy, 26.8% had diagnostic confirmation through cerebrospinal fluid (culture, bacilloscopy, PCR or necropsy. The lethality predictors were: less than 4 years of age, seizures, and severe alterations of consciousness.

  4. Leucemia: fatores prognósticos e genética Leukemia: genetics and prognostic factors

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    Nelson Hamerschlak

    2008-08-01

    Full Text Available OBJETIVO: Apresentar as implicações da genética, particularmente das técnicas de citogenética, no diagnóstico e prognóstico das leucemias. FONTES DOS DADOS: Levantamento de artigos selecionados no MEDLINE, através dos programas educacionais da American Society of Hematology, Portal de Periódicos da CAPES, National Comprehensive Cancer Network e capítulos de livros. SÍNTESE DOS DADOS: Desde a descoberta por Peter C. Nowel e David Hungerford da translocação 9:22 (cromossomo Philadelphia em 1960, a genética passou a ter importante papel na hematologia, possibilitando, neste caso, o diagnóstico da leucemia mielóide crônica e abrindo portas para a pesquisa nesta área para toda a oncologia. Um ponto de altíssimo interesse é a implicação destes achados no prognóstico de diversos tipos de leucemia. Na leucemia mielóide aguda, o cariótipo é fundamental na decisão da terapêutica pós-remissão, e fatores moleculares definem o tratamento em indivíduos de cariótipo normal. Na leucemia mielóide crônica, a evolução clonal está associada à evolução para a fase blástica. Pacientes em uso de imatinibe com perda de resposta podem apresentar mutações do gene ABL. Finalmente, na leucemia linfóide aguda, fatores como hiperdiploidia, t 12:21, estão associados a bom prognóstico, ao passo que portadores da t 4:11 e t 9:22 são considerados de alto risco. CONCLUSÃO: A genética veio para ficar na hematologia e, em particular, no manuseio da leucemia e seus fatores prognósticos. Para a melhor evolução do paciente, estes estudos devem ser sempre realizados, e a conduta terapêutica adequada deve ser tomada.OBJECTIVE: To present the implications of genetics, particularly of cytogenetic techniques, for the diagnosis and prognosis of leukemia. SOURCES: A survey of articles selected from MEDLINE, American Society of Hematology educational programs, the CAPES web portal, the National Comprehensive Cancer Network and textbook

  5. Fatores prognósticos para o desenvolvimento cognitivo de prematuros de muito baixo peso

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    Maria Dalva Barbosa Baker Méio

    2003-06-01

    Full Text Available OBJETIVO: Crianças prematuras, de muito baixo peso, podem apresentar alterações em seu desenvolvimento cognitivo. No Brasil, pouco se conhece sobre a evolução dessas crianças na idade pré-escolar. O objetivo do estudo foi descrever o desenvolvimento cognitivo de uma população de recém-nascidos prematuros de muito baixo peso e verificar possíveis fatores prognósticos para desenvolvimento cognitivo anormal. MÉTODOS: Um estudo de coorte foi realizado com uma população de crianças pré-escolares, nascidas prematuras, de muito baixo peso, entre janeiro de 1991 e setembro de 1993. O desenvolvimento cognitivo foi avaliado por meio do teste WPPSI-R (Wechsler Preschool and Primary Intelligence Scales aplicado por psicólogas, utilizando dois pontos de corte para definição de anormalidade: escores abaixo de 1 e 2, desvios padrões da média (DP. RESULTADOS: Foram avaliadas 79 crianças de quatro a cinco anos de idade. A média do escore total do teste WIPPSI-R foi de 75,6 (±11,9. A incidência de escore total anormal foi de 77,2% e de 32,9% (1DP e 2 DP, respectivamente. Após o ajuste por "tipo de parto", ser pequeno para a idade gestacional (OR=6,19; IC95% 1,60-23,86, ultra-som transfontanela anormal (OR=5,90; IC95% 1,04-9,83 e ser do sexo masculino (OR=3,20; IC 95% 1,32-26,35 foram os fatores que predisseram escore total <70 (2 DP. CONCLUSÃO: Houve maior comprometimento do desenvolvimento cognitivo nas crianças estudadas do que o descrito na literatura. Ser pequeno para idade gestacional, ultra-som transfontanela anormal e sexo masculino foram fatores prognósticos de pior evolução.

  6. Fatores prognósticos no Mieloma Múltiplo Prognostic factors in Multiple Myeloma

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    Gracia A. Martinez

    2007-03-01

    Full Text Available Nos últimos dez anos, grandes mudanças ocorreram no tratamento do MM com a utilização de novas drogas. Frente a estas novas opções de tratamento é essencial reconhecermos parâmetros clínicos ou biológicos que orientem a melhor escolha terapêutica. Mais recentemente foi validado um novo e simples sistema de estadiamento, International Staging System (ISS, baseado nos valores dabeta2 microglobulina e albumina sérica. Os pacientes são classificados em três grupos de risco: Estádio I: beta2M 3,5 g/dl. Mediana de sobrevida de 62 meses; Estádio II: beta2 M 3,5 - 5,5 mg/l. Mediana de sobrevida de 29 meses. Atualmente, a citogenética e achados moleculares estão sendo amplamente reconhecidos como fatores de prognóstico. A deleção do cromossomo 13/13q-, translocação t(4;14, deleção p53 e, mais recentemente, a amplificação da banda cromossômica 1q21 estão associadas a prognóstico reservado.Over the last 10 years, great changes have occurred in the treatment of multiple myeloma (MM due to the use of new drugs. Considering the new options, it is essential to recognize clinical and biological parameters to arrive at the best therapeutic choice. More recently the new International Staging System (ISS for multiple myeloma was validated which utilizes two straight forward laboratory parameters: the beta2 microglobulin (beta2M and albumin levels. Stage I: beta2M 3.5 g/dL with a median survival of 62 months; stage II: beta2M 3.5 to 5.5 g/dL with a median survival of 29 months. The importance of cytogenetics and molecular features as prognostic factors is being recognized. Deletion of chromosome 13 or 13q, the t(4:14 translocation, p53 deletion and amplification of chromosome band 1q21 are all associated with poor prognosis.

  7. Ritual de despedida em familiares de pacientes com prognóstico reservado

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    Márcia Lucrecia Lisbôa

    2003-06-01

    Full Text Available Pesquisa qualitativa que teve por objetivo investigar os efeitos terapêuticos do ritual de despedida na iminência da morte, em familiares de pacientes com prognóstico reservado. Foram estudadas oito famílias de pacientes internados em um Hospital Geral. Utilizou-se o método clínico, as técnicas de estudo de caso e entrevistas pós-óbito, dados submetidos à análise de conteúdo. Os resultados mostraram que os familiares se despediram através da comunicação verbal e não-verbal, da religião, da "liberação", do "estar junto", sendo favoráveis à realização do ritual, destacando o aprendizado, o privilégio de participar e a importância da orientação psicológica. São difuculdades: sentimentos de pena, tristeza, ajuda na aceitação da morte, a aproximação entre os familiares e o paciente, abertura da comunicação, melhoria de condilções para elaborar o luto, redefinição dos relacionamentos com a pessoa ainda em vida.

  8. Fatores prognósticos e impacto da comorbidade na laringectomia fronto-lateral

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    Rogério Aparecido Dedivitis

    Full Text Available OBJETIVO: Avaliar sobrevida, impacto da comorbidade, complicações e fatores de falha da laringectomia como tratamento de tumores malignos glóticos. MÉTODOS: Foram analisadas 38 pacientes com tumor glótico sob estadiamento clínico T1b/T2N0M0 submetidos à laringectomia fronto-lateral com reconstrução, de janeiro de 1995 a dezembro de 2006. Foram avaliados os resultados oncológicos, comorbidades (através da escala Adult Comorbidity Evaluation - 27 ACE-27 e complicações, sendo correlacionados com dados demográficos e características do tumor. RESULTADOS: Oito pacientes apresentaram recidiva local e foram resgatados cirurgicamente. Complicações não foram verificadas em 33 pacientes. Não houve diferença significativa das sobrevidas global em cinco anos e livre de doença ao considerarem-se as diferentes categorias de comorbidades. Somente o envolvimento patológico das margens mostrou diferenças significativas na sobrevida global (p=0,0033 e sobrevida livre de doença (p<0,0001. CONCLUSÃO: A sobrevida global em cinco anos foi de 67,6% e a sobrevida livre de doença de 73,7%; a comorbidade não representou fator prognóstico independente; o índice de complicações pós-operatórias foi de 13,2% e somente o envolvimento patológico das margens mostrou diferenças significativas na sobrevida global e livre de doença.

  9. Fatores prognósticos nas síndromes mielodisplásicas Prognostic factors for myelodysplastic syndromes

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    Alexandre G. Apa

    2006-09-01

    Full Text Available As síndromes mielodisplásicas compreendem um conjunto heterogêneo de doenças hematopoéticas que se caracterizam por hematopoese ineficaz e se apresentam geralmente com citopenias no sangue periférico, medula óssea hipercelular e displasia na diferenciação celular. Vários fatores clínicos e laboratoriais foram analisados como prognósticos. O objetivo dessa revisão é analisar os sistemas prognósticos avaliando sobrevida global e abordagem terapêutica. A avaliação do sistema WPSS, que alia grupos de riscos citogenéticos e a presença ou não de dependência transfusional define cinco grupos de riscos com diferença estatística em termos de sobrevida global e risco de transformação leucêmica. A proposta formulada é a avaliação do sistema WPSS como sistema prognóstico capaz de substituir o IPSS a fim de melhor definir os grupos de risco e diferentes abordagens terapêuticas.The myelodysplastic syndromes represent a heterogeneous group of haematopoietic disorders characterized by ineffective haematopoiesis, peripheral cytopenias, hypercellular bone marrow and dysplastic haematopoiesis. Several laboratory and clinical features have been analysed as prognostic factors. The aim of this review is to evaluate the prognostic scoring systems focusing on overall survival and therapeutic approach. The WPSS evaluation includes both cytogenetic risk groups and transfusional necessities. It has five well-defined risk groups with statistical divergences related to overall survival and leukemic transformation risk. Our proposal is to evaluate the WPSS as a prognostic scoring system able to replace the IPSS, in order to establish a better definition of the risk groups and the different therapeutic approaches.

  10. Cardiomiopatia chagásica: prognóstico no perfil clínico-hemodinâmico C

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    Juliano Cardoso

    2010-10-01

    Full Text Available FUNDAMENTO: Os pacientes com insuficiência cardíaca (IC que são internados apresentando má perfusão e congestão (perfil clínico-hemodinâmico C constituem o grupo que evolui com pior prognóstico na IC descompensada. Entretanto, há pouca informação na literatura se a etiologia da cardiopatia influencia na evolução dos pacientes na fase avançada. OBJETIVO: Avaliar a evolução dos pacientes que se internaram com perfil clínico-hemodinâmico C e verificar o papel da etiologia nesta fase. MÉTODOS: Um estudo de coorte foi realizado incluindo pacientes com fração de ejeção do ventrículo esquerdo (FEVE < 45,0%, classe funcional IV e internação hospitalar apresentando perfil clínico-hemodinâmico C. O grupo foi dividido em pacientes portadores de cardiomiopatia chagásica (Ch e não chagásica (NCh. Para análise estatística foram utilizados os testes t de Student, exato de Fisher, qui-quadrado e o programa SPSS. O significante de p < 0,05 foi considerado. RESULTADOS: Cem pacientes, com idade média de 57,6 ± 15,1 anos e FEVE média de 23,8 ± 8,5%, foram incluídos. Dentre os pacientes estudados, 33,0% eram chagásicos e, na comparação com os NCh, apresentaram menor pressão arterial sistólica (Ch 89,3 ± 17,1 mmHg versus NCh 98,8 ± 21,7 mmHg; p = 0,03 e menor idade média - Ch 52,9 ± 14,5 anos versus NCh 59,8 ± 14,9 anos; p = 0,03. Durante o acompanhamento de 25 meses, a mortalidade foi de 66,7% nos Ch e de 37,3% nos NCh (p = 0,019. A etiologia chagásica foi um marcador independente de mau prognóstico na análise multivariada com razão de risco de 2,75 (IC 95,0%; 1,35 - 5,63. CONCLUSÃO: Nos pacientes com IC avançada, a etiologia chagásica é um importante preditor de pior prognóstico.

  11. Intolerância glicêmica e o prognóstico perinatal em gestantes utilizando anti-retrovirais

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    El Beitune Patrícia

    2003-01-01

    Full Text Available OBJETIVOS: estudar o efeito das drogas anti-retrovirais sobre o metabolismo glicêmico em gestantes portadoras do HIV-1 e a ação dessas medicações sobre o prognóstico perinatal. MÉTODOS: estudo prospectivo realizado em 57 gestantes divididas em três grupos: grupo AZT, utilizando zidovudina (n=20; grupo TT, utilizando zidovudina+lamivudina+nelfinavir (n=25, e grupo controle, gestantes normais (n=12. Obteve-se a área sob a curva (ASC das glicemias após teste oral de tolerância à glicose com 75 g de glicose em quatro oportunidades durante a gravidez (1º=14-20 semanas, 2º=21-26 semanas, 3º=27-32 semanas e 4º=33-38 semanas. O prognóstico perinatal levou em consideração as taxas de prematuridade, restrição de crescimento intra-útero (RCIU, baixo peso ao nascer, mortalidade perinatal e transmissão vertical do HIV-1. Os dados foram analisados utilizando-se os testes não paramétricos do c², de Friedman e de Kruskal-Wallis. RESULTADOS: os valores da mediana da ASC foi de 11.685 mg/dL-2h para o grupo controle, 13.477 mg/dL-2h para o grupo AZT e 13.650 mg/dL-2h para o grupo TT (p=0,049. Não se observou efeito deletério dos anti-retrovirais sobre as taxas de prematuridade, baixo peso ao nascer, RCIU e índices de Apgar. Não houve nenhum caso de transmissão vertical do HIV-1. CONCLUSÕES: verificou-se o desenvolvimento de intolerância glicêmica em gestantes que utilizaram tratamento tríplice, não sendo observado naquelas que utilizaram apenas AZT. Não houve efeitos deletérios dos anti-retrovirais sobre o prognóstico perinatal.

  12. Hipotermia terapêutica após parada cardíaca: preditores de prognóstico

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    Rodrigo Nazário Leão

    2015-12-01

    Full Text Available Resumo Objetivo: A determinação do prognóstico de pacientes em coma após parada cardíaca tem implicações clínicas, éticas e sociais. Exame neurológico, marcadores de imagem e bioquímicos são ferramentas úteis e bem aceitas na previsão da recuperação. Com o advento da hipotermia terapêutica, tais informações devem de ser confirmadas. Neste estudo procurou-se determinar a validade de diferentes marcadores que podem ser utilizados na detecção de pacientes com mau prognóstico durante um protocolo de hipotermia. Métodos: Foram coletados prospectivamente os dados de pacientes adultos, internados após parada cardíaca em nossa unidade de terapia intensiva para realização de protocolo de hipotermia. Nosso intuito foi realizar um estudo descritivo e analítico para analisar a relação entre os dados clínicos, parâmetros neurofisiológicos, de imagem e bioquímicos, e o desfecho após 6 meses, conforme definido pela escala Cerebral Performance Categories (bom, se 1-2, e mau, se 3-5. Foi coletada uma amostra para determinação de neuroenolase após 72 horas. Os exames de imagem e neurofisiológicos foram realizados 24 horas após o período de reaquecimento. Resultados: Foram incluídos 67 pacientes, dos quais 12 tiveram evolução neurológica favorável. Fibrilação ventricular e atividade teta no eletroencefalograma se associaram a bom prognóstico. Pacientes submetidos a resfriamento mais rápido (tempo médio de 163 versus 312 minutos, com lesão cerebral causada por hipóxia/isquemia detectada na ressonância nuclear magnética ou níveis de neuroenolase superiores a 58ng/mL se associaram a desfecho neurológico desfavorável (p < 0,05. Conclusão: A presença de lesão cerebral causada por hipóxia/isquemia e de neuroenolase foram fortes preditores de má evolução neurológica. Apesar da crença de que atingir rapidamente a temperatura alvo da hipotermia melhora o prognóstico neurológico, nosso estudo demonstrou

  13. Prognóstico pulmonar em prematuros Pulmonary prognosis in preterm infants

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    Luciana Friedrich

    2005-03-01

    Full Text Available OBJETIVO: O aumento da sobrevida de prematuros traz o desafio de lidar com um amplo espectro de doenças pulmonares crônicas, incluindo displasia broncopulmonar, síndrome de Wilson-Mikity e sibilância recorrente. Este artigo discute o prognóstico pulmonar clínico e funcional de prematuros na infância e na adolescência. FONTE DE DADOS: Foi realizada pesquisa no MEDLINE de publicações entre 1970 e 2004 que abordassem função e crescimento pulmonar de prematuros, bem como a evolução clínica dos mesmos. SÍNTESE DOS DADOS: Eventos pré e pós-natais como insuficiência placentária, tabagismo, infecções, oxigênio e ventilação mecânica exercem efeitos importantes no desenvolvimento pulmonar, podendo conduzir a doenças pulmonares crônicas, sendo a displasia broncopulmonar a complicação clínica mais severa. No entanto, perdas significativas de função pulmonar também podem ocorrer em prematuros sem critérios de displasia broncopulmonar e que não apresentaram doença respiratória neonatal significativa. Nestes pacientes, o impacto da prematuridade sobre o sistema respiratório é freqüentemente subestimado. Clinicamente, observa-se incidência aumentada de pneumonias e bronquiolites, re-hospitalizações por doenças respiratórias, tosse e sibilância crônicas e hiper-reatividade brônquica. Posteriormente, percebe-se uma tendência à normalização da função pulmonar, mas persistem fluxos reduzidos, menor tolerância a exercícios e hiper-reatividade brônquica. CONCLUSÕES: A prematuridade, os eventos que a provocam e as intervenções que dela decorrem alteram de maneira permanente, em maior ou menor grau, o desenvolvimento do sistema respiratório. São necessários estudos adicionais para esclarecer o efeito de cada um desses insultos perinatais no desenvolvimento do sistema respiratório.OBJECTIVE: The increased survival of preterm infants poses the challenge of dealing with a wide range of chronic pulmonary

  14. Fatores prognósticos em fibrose pulmonar idiopática Prognostic factors in idiopathic pulmonary fibrosis

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    ADALBERTO SPERB RUBIN

    2000-09-01

    Full Text Available Com o objetivo de avaliar quais fatores prognósticos são significativos na sobrevida de pacientes com fibrose pulmonar idiopática (FPI, foram estudados 117 casos com comprovação histológica da doença, internados no Pavilhão Pereira Filho entre 1970 e 1996. Todos os pacientes realizaram radiologia convencional de tórax, espirometria e preencheram um questionário padronizado no momento da internação. Foram também realizados medida da difusão (34 casos, capacidade pulmonar total (28, gasometria (106, lavado broncoalveolar (39, provas reumatismais (45 e tomografia computadorizada de tórax (24. Para uma análise mais específica, os pacientes foram dividos em dois grupos: grupo A (sobrevida até dois anos - 55 pacientes e grupo B (sobrevida maior que cinco anos - 24 pacientes, sendo estas características também analisadas de acordo com a significância em relação à sobrevida. Foram considerados fatores indicativos de pior prognóstico a idade avançada, a duração prolongada de sintomas, a gravidade da dispnéia, a redução da CVF, da DCO, da PaO2 e da SaO2, a intensidade do faveolamento e o grau de profusão do padrão reticular na TCAR. Estiveram também associados à menor sobrevida os valores menores de VEF1 e CPT. A utilização destes critérios de gravidade que apresentaram significância estatística, quando utilizados em conjunto, pode determinar uma avaliação prognóstica mais apurada em pacientes portadores de FPI, com implicações terapêuticas e sociais relevantes para seu manejo e acompanhamento.In order to evaluate which prognostic factors were significant to the survival of patients with idiopathic pulmonary fibrosis (IPF, 121 histologically confirmed cases of the disease were studied at the Pereira Filho Hospital from 1970 to 1996. All patients were submitted to a standard thorax X-ray and spirometry and answered a standardized questionnaire when admitted to hospital. They also underwent diffusion tests (34

  15. Uso do escore prognóstico APACHE II e ATN-ISS em insuficiência renal aguda tratada dentro e fora da unidade de terapia intensiva

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    Fernandes,Natáia Maria da Silva; Pinto,Patrícia dos Santos; Lacet,Thiago Bento de Paiva; Rodrigues,Dominique Fonseca; Bastos,Marcus Gomes; Stella,Sérgio Reinaldo; Cendoroglo Neto,Miguel

    2009-01-01

    INTRODUÇÃO: A insuficiência renal aguda (IRA) mantém alta prevalência, morbidade e mortalidade. OBJETIVO: Comparar o uso do escore prognóstico APACHE II com o ATN-ISS e determinar se o APACHE II pode ser utilizado para pacientes com IRA, fora da UTI. MÉTODOS: Coorte prospectiva, 205 pacientes com IRA. Analisamos dados demográficos, condições pré-existentes, falência de órgãos e características da IRA. Os escores prognósticos foram realizados no dia da avaliação do nefrologista. RESULTADOS: A ...

  16. Fatores prognósticos para o desfecho do tratamento da tuberculose pulmonar em Recife, Pernambuco, Brasil

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    Maria de Fatima Militão de Albuquerque

    2001-06-01

    Full Text Available Objetivos. O objetivo deste estudo caso-controle foi identificar fatores prognósticos para desfecho do tratamento da tuberculose pulmonar em 297 pacientes (Hospital das Clínicas, Universidade Federal de Pernambuco, Brasil entre 1994 e 1999. Materiais e métodos. Foram considerados casos indivíduos com alta por óbito, abandono ou falência do tratamento. Os controles foram indivíduos com alta por cura. Foram realizadas análises uni e multivariada com as variáveis independentes sexo; idade; escolaridade; hábito de fumar; hábito de ingerir álcool; tratamento anterior para tuberculose; resposta ao teste tuberculínico; sorologia para HIV; grau de resistência aos antimicrobianos; resultado da pesquisa direta de bacilos álcool-ácido-resistentes; esquema terapêutico utilizado. Além disso, repetiram-se as análises uni e multivariada considerando como casos apenas os óbitos e os indivíduos com falência do tratamento. Resultados. A ingestão excessiva de álcool (OR = 2,58; P = 0,014, a co-infecção pelo HIV (OR = 3,40; P = 0,028, o a tratamento anterior para tuberculose (OR = 4,89; P < 0,001 e resistência a duas ou mais drogas antituberculose (OR = 3,49; P = 0,017 foram fatores de risco para o insucesso do tratamento. Na segunda análise multivariada, excluindo os casos de abandono, não houve associação entre a o ingestão excessiva de álcool e desfecho do tratamento, mantendo-se as demais associações, o que sugere uma estreita relação entre o abandono do tratamento e o etilismo. Conclusões. Os fatores prognósticos para insucesso do tratamento da tuberculose pulmonar entre os indivíduos estudados estão interrelacionados, sendo de natureza biológica, clínica e social. Devem ser identificados no início do tratamento para que sejam implementados procedimentos diferenciados de acompanhamento, tais como tratamento diretamente supervisionado, de forma a fortalecer o controle da tuberculose em nível local.

  17. Bloqueio completo do ramo esquerdo esforço-induzido: prevalência e prognóstico

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    Ricardo Stein

    2011-07-01

    Full Text Available FUNDAMENTO: O bloqueio completo do ramo esquerdo esforço-induzido (BCRE E-I é um achado infrequente ao teste de exercício e sua prevalência e significado prognóstico não são claros. OBJETIVO: Avaliar de forma longitudinal a prevalência e o significado prognóstico do BCRE E-I em homens americanos veteranos de guerra. MÉTODOS: Avaliamos 9.623 pacientes que realizaram ergometria em esteira (TE entre 1987 e 2007. Os desfechos foram comparados entre aqueles com TE NL, os com BCRE E-I e os que apresentaram Dep ST anormal. A mortalidade e a causa das mortes foram identificadas de forma cega para os resultados do TE. RESULTADOS: Nesta coorte prospectiva, 6922 indivíduos apresentaram TE NL (57,2 ± 11,4 anos, 1.739 apresentaram Dep ST anormal (62,7 ± 9,8 anos e 38 casos de BCRE E-I foram identificados (65,2 ± 11,9 anos. A prevalência do BCRE E-I foi 0,38%. Após 8,8 anos, ocorreram 1.699 mortes por todas as causas e 610 mortes cardiovasculares (CV. Doença arterial coronária e insuficiência cardíaca foram mais prevalentes nos pacientes com BCRE E-I. Pacientes com BCRE E-I tiveram razão de azar de 2,37 (p = 0,002 para mortalidade por todas as causas, mas a mesma não foi significativa quando ajustada para idade ou quando a mortalidade cardiovascular foi o desfecho avaliado. CONCLUSÃO: BCRE E-I é um achado raro. Indivíduos com BCRE E-I apresentam maior mortalidade por todas as causas quando comparados aqueles com TE NL. No entanto, tal fato é explicado por esses pacientes serem significativamente mais velhos e por apresentarem mais enfermidades cardiovasculares associadas.

  18. Valor prognóstico de dados clínicos em paralisia de Bell The value of prognostic clinical data in Bell's palsy

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    Cristiane A. Kasse

    2005-08-01

    Full Text Available Com o advento dos testes eletrofisiológicos, a avaliação clínica parece ter perdido interesse na paralisia de Bell. A eletroneuronografia (ENoG associada ao estadiamento clínico da doença é o método mais freqüentemente utilizado para mensurar o prognóstico da paralisia de Bell. Entretanto, a ENoG constitui-se em um teste eletrofisiológico ainda não universalmente disponível, especialmente nos serviços de emergência. OBJETIVO: Estudar a medida do prognóstico da paralisia de Bell com base nos dados clínicos e no teste de estimulação elétrica mínima, teste de Hilger, permitindo assim uma previsão de prognóstico segura e factível na maioria dos serviços. FORMA DE ESTUDO: coorte historica. MATERIAL E MÉTODO: Estudo coorte retrospectivo, analisando 1521 casos de paralisia de Bell, correlacionando-se os dados clínicos sexo, idade, lado da paralisia, modo de instalação, sintomas prévios, sintomas associados e os resultados do teste de estimulação elétrica mínima (Hilger, com a evolução da paralisia após 6 meses. RESULTADO: O estudo desses dados indicou que pacientes acima de 60 anos apresentaram prognóstico pior em comparação com pacientes com idade abaixo de 30 anos; o modo de instalação progressiva, a ausência de sintomas prévios, a presença de vertigem concomitante à paralisia e resposta acima de 3,5 mm no teste de Hilger estiveram relacionados com mau prognóstico. Por outro lado, a ausência de sintomas concomitantes, a diminuição do lacrimejamento e o início súbito foram relacionados com bom prognóstico. CONCLUSÃO: A análise de fatores clínicos, associada ao teste de Hilger, pode indicar o prognóstico da paralisia facial com reduzida margem de erro, sendo uma alternativa bastante interessante especialmente quando não há disponibilidade da ENoG.Electroneurography (ENoG and clinical staging are currently the methods of choice to indicate prognosis in Bell's palsy, although ENoG is an

  19. Procalcitonina como biomarcador de prognóstico da sepse grave e choque séptico

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    José Raimundo Araujo de Azevedo

    Full Text Available OBJETIVO: Avaliar a tendência da concentração plasmática e do clearance de procalcitonina (PCT-c como biomarcadores de prognóstico de pacientes com sepse grave e choque séptico, comparado a um outro marcador precoce de prognóstico representado pelo número de critérios de SIRS no momento do diagnóstico da sepse. MÉTODOS: Estudo de coorte prospectivo observacional onde foram incluídos pacientes com sepse grave e choque séptico. A concentração sérica de procalcitonina foi determinada no momento do diagnóstico da sepse e após 24 e 48 horas. Foram coletados dados demográficos, escore APACHE IV, escore SOFA na chegada, número de critérios de SIRS no momento do diagnóstico, sitio da infecção e resultados microbiológicos. RESULTADOS: Vinte e oito pacientes foram incluídos, 19 clínicos e nove cirúrgicos. Em 13 (46,4% a fonte da sepse foi pulmonar, em sete abdominal (25,0%, em cinco urinária (17,9% e de partes moles em três casos (10,7%. Quinze pacientes tinham sepse grave e 13 choque séptico. A mortalidade global foi cinco pacientes (17,9%, três deles com choque séptico. Vinte e oito determinações de PCT foram realizadas no momento do diagnóstico da sepse, 27 após 24 horas e 26 após 48 horas. A concentração inicial não se mostrou expressivamente diferente entre os grupos sobreviventes e não sobreviventes, mas as diferenças entre os dois grupos após 24 e 48 horas alcançaram significância estatística expressiva. Não se observou diferença em relação ao número de critérios de SIRS. O clearance de procalcitonina de 24 horas mostrou-se expressivamente mais elevado no grupo de sobreviventes (-3,0 versus -300,0, p=0,028. Embora o clearance de procalcitonina de 48 horas tenha mostrado resultado mais elevado no grupo de sobreviventes comparado aos não sobreviventes, a diferença não alcançou significância estatística. CONCLUSÃO: Concentrações persistentemente elevadas de procalcitonina no plasma, assim

  20. Avaliação da proliferação celular como indicador prognóstico para mastocitomas cutâneos caninos Evaluation of cellular proliferation as prognostic indicator for canine cutaneous mast cell tumors

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    Ricardo De F. Strefezzi

    2010-07-01

    Full Text Available Este estudo teve como objetivo avaliar o valor prognóstico de marcadores de proliferação celular em casos de mastocitomas cutâneos caninos. Vinte e três casos foram analisados quanto à expressão imuno-histoquímica de Ki67 e do Antígeno Nuclear de Proliferação Celular (PCNA, sendo subsequentemente acompanhados clinicamente. Observou-se que a expressão de Ki67 mantém relação negativa com a tradicional graduação histopatológica (p= 0,0418; pThis study evaluated the prognostic value of cell proliferation markers for canine cutaneous mast cell tumor cases. Twenty-three cases were analyzed with regard to immuno-histochemical expression of Ki67 and Proliferating Cell Nuclear Antigen (PCNA, and were clinically followed up. Ki67 expression was related to the traditional histopathological grading (p= 0.0418; p<0.05 between grades I and III, and was a reliable indicator of post-surgical survival (p=0.0089. PCNA immunoexpression did not show statistically significant values in the prediction of disease-related mortality and survival, although it is correlated to Ki67 expression. These results confirm that information about tumoral proliferative activity through Ki67 immunohistochemical detection can improve canine cutaneous mast cell tumor grading with regard to malignancy.

  1. Variantes do carcinoma papilífero da tireoide: associação com fatores prognósticos histopatológicos

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    Fábio Muradás Girardi

    2013-12-01

    Full Text Available O carcinoma papilífero é a malignidade tireoidiana mais comum. Muitas variantes desse tumor foram descritas, com diferentes características morfológicas e moleculares. Embora a maioria dos casos apresente um excelente prognóstico, a relação entre a arquitetura tumoral e o comportamento biológico dessas neoplasias ainda permanece controversa. OBJETIVO: Apresentamos a experiência de um único serviço acerca da prevalência das variantes do carcinoma papilífero da tireoide e sua relação com os demais fatores prognósticos histopatológicos. MÉTODO: Estudo retrospectivo envolvendo todos os casos submetidos à tireoidectomia por carcinoma papilífero na mesma Instituição ao longo de 11 anos de estudo. RESULTADOS: Foram incluídos 517 pacientes, sendo 81,9% dos casos representados mulheres. A média de idade foi de 47,2 anos. As variantes reconhecidas por terem maior potencial de agressividade corresponderam a 5,6% da amostra. Observamos associação desses subtipos tumorais com maior diâmetro da lesão, estadiamento T, invasão linfovascular e da cápsula da glândula. CONCLUSÃO: Um pequeno percentual de casos de carcinomas papilíferos é representado por variantes reconhecidas por seu maior potencial de agressividade. Existem associações entre essas variantes e diversos outros fatores histopatológicos já reconhecidos por seu valor prognóstico, o que pode, por si, só influenciar no desfecho desses casos.

  2. Potencial evocado auditivo de tronco encefálico no prognóstico do coma superficial

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    Libia Camargo Ribeiro Leite

    2013-08-01

    Full Text Available O coma é a redução persistente do nível de consciência, arresponsivo a estímulos, devido à baixa atividade cerebral. Para verificar o nível de consciência, um recurso frequentemente utilizado é a Escala de Coma de Glasgow. Outro método que se destaca é o Potencial Evocado Auditivo de Tronco Encefálico, o qual avalia a atividade elétrica das vias auditivas ascendentes, desde o trajeto periférico até o mesencéfalo. O exame é simples, imune a medicamentos depressores e ambientes eletricamente carregados, sendo o mais adequado dos potenciais para a monitoração dos estados de coma. O presente estudo teve por objetivo verificar as características do Potencial Evocado Auditivo de Tronco Encefálico no estado de coma leve (Glasgow 7 - 8 e suas respectivas contribuições. Foi realizado um estudo prospectivo transversal em dois pacientes em coma (Glasgow 7, estado secundário a traumatismo cranioencefálico. Os resultados do exame evidenciaram presença de atividade elétrica em toda extensão da via estudada, em ambos os casos, com indicações de diferentes alterações, quanto à redução na latência entre os intervalos, morfologia e replicação das ondas. Tais diferenças foram contempladas com a evolução de cada caso: caso 1 evoluiu a alta hospitalar e caso 2 evoluiu a óbito. Os resultados confirmaram os achados da literatura, que descreve que a presença do Potencial Evocado Auditivo de Tronco Encefálico normal está associada à boa evolução do caso clínico, enquanto alterações no exame podem sinalizar para um mau prognóstico.

  3. Fatores prognósticos para o desenvolvimento cognitivo de prematuros de muito baixo peso Prognostic factors for cognitive development of very low birth weight premature children

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    Maria Dalva Barbosa Baker Méio

    2003-06-01

    Full Text Available OBJETIVO: Crianças prematuras, de muito baixo peso, podem apresentar alterações em seu desenvolvimento cognitivo. No Brasil, pouco se conhece sobre a evolução dessas crianças na idade pré-escolar. O objetivo do estudo foi descrever o desenvolvimento cognitivo de uma população de recém-nascidos prematuros de muito baixo peso e verificar possíveis fatores prognósticos para desenvolvimento cognitivo anormal. MÉTODOS: Um estudo de coorte foi realizado com uma população de crianças pré-escolares, nascidas prematuras, de muito baixo peso, entre janeiro de 1991 e setembro de 1993. O desenvolvimento cognitivo foi avaliado por meio do teste WPPSI-R (Wechsler Preschool and Primary Intelligence Scales aplicado por psicólogas, utilizando dois pontos de corte para definição de anormalidade: escores abaixo de 1 e 2, desvios padrões da média (DP. RESULTADOS: Foram avaliadas 79 crianças de quatro a cinco anos de idade. A média do escore total do teste WIPPSI-R foi de 75,6 (±11,9. A incidência de escore total anormal foi de 77,2% e de 32,9% (1DP e 2 DP, respectivamente. Após o ajuste por "tipo de parto", ser pequeno para a idade gestacional (OR=6,19; IC95% 1,60-23,86, ultra-som transfontanela anormal (OR=5,90; IC95% 1,04-9,83 e ser do sexo masculino (OR=3,20; IC 95% 1,32-26,35 foram os fatores que predisseram escore total OBJECTIVE: Very low birth weight premature children often show cognitive development abnormalities. There is scarce information about the outcome of these children at preschool age in Brazil.The objective of the study is to describe the cognitive development of a population of premature newborns and to assess possible prognostic factors for abnormalities. METHODS: A cohort study was conducted in a preschool children population whose subjects were very low birth weight premature babies born between January 1991 and September 1993. WPPSI-R Test was used for cognitive evaluation and it was applied by psychologists. Two

  4. Terapia oclusiva em ambliopia: fatores prognósticos Occlusion therapy in amblyopia: factors that influence the outcome

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    Ana Carolina Fava Salata

    2001-04-01

    Full Text Available Objetivos: Ambliopia é o defeito visual mais comum em crianças e por mais de 250 anos a terapia oclusiva vem sendo o melhor tratamento. Sendo assim, propusemo-nos a determinar os fatores que influenciam no sucesso do tratamento da ambliopia por terapia oclusiva em nosso meio. Métodos: Foi realizado um estudo retrospectivo com 169 crianças amblíopes atendidas no Ambulatório de Ambliopia do Hospital de Clínicas da UNICAMP, Campinas (SP, entre janeiro de 1996 e maio de 1998. A população atendida foi classificada quanto ao sexo, idade de início do tratamento por faixa etária (3 grupos, olho afetado, tipo de ambliopia (estrabísmica, anisometrópica, por deprivação, associação de dois tipos, tempo de seguimento, gravidade da ambliopia (leve, moderada, grave, adesão ao tratamento (regular, irregular e resposta obtida (cura, melhora, sem cura. Resultados: A adesão ao tratamento não diferiu entre as faixas etárias (p=0,68 e não foi influenciada pela gravidade da ambliopia (p=0,82. Dos pacientes estudados 52,67% curaram-se, 19,52% melhoraram e 27,81% não obtiveram cura. Os pacientes com adesão regular tiveram índice de cura significativamente maior do que os pacientes com adesão irregular (p=0,0009. O resultado do tratamento não dependeu da idade de início do mesmo (p=0,39 e da gravidade da ambliopia (p=0,30. Conclusão: Concluímos, assim, que, no nosso grupo de estudo, a adesão é o principal fator prognóstico no sucesso da terapia oclusiva.Purpose: Amblyopia is the most common form of visual problem in children and for more than 250 years occlusion therapy is the standard treatment. Thus our purpose is to identify the factors that influence the outcome of amblyopia treatment with occlusion therapy. Methods: We reviewed 169 amblyopic children seen in the outpatient clinic of amblyopia of the Campinas State University, between January 1996 and May 1998. Patients were analyzed regar-ding sex, age at start of treatment (3

  5. Polimorfismo G894T da óxido nítrico-sintetase endotelial e o prognóstico na insuficiência cardíaca

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    Oziel Marcio Araujo Tardin

    2013-10-01

    Full Text Available FUNDAMENTO: Estudos prévios avaliaram o papel do polimorfismo genético da enzima óxido nítrico-sintetase endotelial sobre o prognóstico na insuficiência cardíaca. Entretanto, faltam estudos relacionando o G894T e a insuficiência cardíaca na população brasileira. OBJETIVO: Avaliar a associação do G894T com o prognóstico de amostra de pacientes brasileiros com insuficiência cardíaca. MÉTODOS: Coorte com 145 pacientes com insuficiência cardíaca sistólica, num segmento de 40 meses (média = 22 meses, em dois hospitais universitários do Estado do Rio de Janeiro. Foi avaliada a relação do G894T com os desfechos: remodelamento reverso; melhora da classe funcional (NYHA; taxas de mortalidade e hospitalização. Os diâmetros do átrio e ventrículo esquerdos e a fração de ejeção do ventrículo esquerdo foram medidos na admissão e após 6 meses, para avaliação do remodelamento reverso. A melhora na classe funcional foi avaliada após 6 meses e as taxas de mortalidade e de hospitalização durante todo o seguimento. A raça foi autodeclarada. O polimorfismo G894T foi analisado por reação em cadeia de polimerase e por análise do polimorfismo dos fragmentos de restrição. RESULTADOS: A frequência genotípica foi GG (40%, GT (48,3% e TT (11,7%, e a frequência alélica foi guanina (64,1% e tiamina (35,8%. Não houve diferença entre as frequências genotípica ou alélica conforme a raça autodeclarada, tampouco conforme as características basais. Não houve relação entre o genótipo ou a frequência alélica e os desfechos analisados. CONCLUSÃO: Não se observou associação do polimorfismo G894T (Glu298Asp com o prognóstico de amostra de pacientes ambulatoriais brasileiros com insuficiência cardíaca sistólica.

  6. Synovial sarcoma of the extremities: prognostic factors for 20 nonmetastatic cases and a new histologic grading system with prognostic significance Sarcoma sinovial das extremidades: fatores de prognóstico em 20 casos não-metastáticos e um novo sistema de graduação histológica com significado prognóstico

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    André Mathias Baptista

    2006-10-01

    Full Text Available PURPOSE: To evaluate 20 cases of nonmetastatic synovial sarcoma of the extremities regarding prognostic factors, and to propose a histologic grading system with prognostic significance. METHODS: The cases of 20 patients (14 females and 6 males with nonmetastatic synovial sarcomas of the extremities treated between 1985 and 1998, were retrospectively evaluated regarding prognostic factors. A histologic grading system with prognostic significance is proposed. RESULTS: The mean follow-up period was 48.4 months (range, 16-116 months. There was local recurrence in 3 cases (15%, microscopic surgical margin being the only prognostic factor identified. Seven patients (35% died of the disease in a mean postoperative period of 31.7 months (range, 16-53 months, all with pulmonary or brain metastasis. The survival rate was 65% in 48.4 months of follow-up. CONCLUSION: The unfavorable prognostic factors identified regarding survival were high histologic grade, tumors proximal to the knee or elbow, and spontaneous tumor necrosis over 25%. Local recurrence did not have influence on survival in this study. The presence of mast cells appears to have a positive influence on survival, although statistical significance was not reached (P = 0.07. The oncologic and functional result was good in 6 cases (30%, regular in 7 (35%, and poor in 7 cases (35%.OBJETIVO: Avaliar casos de sarcoma sinovial não-metastático das extremidades no que se refere a fatores prognósticos, e propor um sistema histológico de pontuação com significado prognóstico. MATERIAL E MÉTODO: Vinte casos (14 do sexo feminino e 6 do sexo masculino de sarcomas sinoviais não-metastáticos das extremidades tratados entre 1985 e 1998 no departamento de Ortopedia foram avaliados retrospectivamente no que se refere a fatores prognósticos e está sendo proposto um sistema de pontuação histológico com significado prognóstico. RESULTADOS: A média dos períodos de acompanhamento foi 48,4 meses (m

  7. Prognostic value of proton magnetic resonance spectroscopy findings in near drowning patients: reversibility of the early metabolite abnormalities relates with a good outcome Valor prognóstico da espectroscopia de prótons em vítimas de quase-afogamento: reversibilidade das anormalidades metabólicas precoces relacionou-se com bom prognóstico

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    Maria de Fátima Vasco Aragão

    2009-03-01

    Full Text Available In two children with near drowning hypoxic encephalopathy and normal-appearing structural MRI, acute proton magnetic resonance spectroscopy (¹H MRS showed biochemical alterations that correctly indicated prognosis and helped to guide management decisions. Elevation of the lipid-lactate and glutamine-glutamate peaks, on the early (72 hour ¹H MRS, predicts a poor prognosis. Absence of lipid-lactate and glutamine-glutamate peaks on the early ¹H MRS and reversibility of early mild metabolite abnormalities on follow up examination relates with good outcome.Em duas criancas vítimas de quase-afogamento com encefalopatia hipóxico-isquêmica, que apresentaram ressonância magnética por imagem normal, a espectroscopia de prótons por ressonância magnética (¹H MRS na fase aguda mostrou alterações bioquímicas que corretamente indicaram o prognóstico e ajudaram a guiar o manejo terapêutico. Elevação dos picos de lipídeo-lactato e glutamina-glutamato na ¹H MRS precoce realizada com 72 horas previu um mau prognóstico. Relacionaram-se com bom prognóstico; a ausência dos picos de lipídeo-lactato e glutamina-glutamato na ¹H MRS precoce, e a reversibilidade no exame de controle (3 meses das discretas anormalidades metabólicas encontradas no primeiro exame.

  8. O médico frente ao diagnóstico e prognóstico do câncer avançado The physician when facing diagnosis and prognosis of advanced cancer

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    Etelvino de Souza Trindade

    2007-02-01

    Full Text Available OBJETIVO: Avaliar a postura de médicos frente à informação do diagnóstico e prognóstico de câncer aos pacientes, familiares ou ambos, incluindo uma análise bioética do conflito verificado entre beneficência, respeito à autonomia do paciente e paternalismo. MÉTODOS: Foram entrevistados 38 médicos responsáveis por pacientes com neoplasias malignas em um hospital terciário. O questionário foi dividido em duas partes. Uma com dados gerais do entrevistado e outra com perguntas específicas sobre a transmissão das informações ao paciente e também avaliação da compreensão do médico sobre beneficência. RESULTADOS: Embora 97,4% dos médicos em geral informem o diagnóstico aos seus pacientes, nos casos de doença terminal, 50% se valem da família como apoio. Com relação à informação sobre prognóstico fatal, os que comunicam somente à família foram 63,1%, enquanto 31,6% preferem passar a informação diretamente ao paciente. O estudo mostrou que os profissionais confundem beneficência com paternalismo. CONCLUSÃO: Os médicos têm o hábito de informar o diagnóstico aos seus pacientes. Na impossibilidade de recursos curativos, as atitudes tornam-se conflitantes no que concerne aos princípios da beneficência e autonomia. O número de médicos que acreditam no paternalismo como forma de beneficência é ainda significativo. A atitude paternalista emerge principalmente quando os recursos terapêuticos tornam-se não resolutivos.Biotechnological scientific progress has brought about some misunderstanding between advances and ethical decisions. The relationship physician-patient when facing seriously ill patients has been altered. OBJECTIVE: To evaluate the physician's attitude when facing disclosure to patient, family or both of cancer diagnosis and prognosis including also a bioethical analysis about the conflicts between beneficence, respect for patient autonomy and paternalism. METHODS: Thirty-eight physicians

  9. Outcome in critically ill cancer patients: past and present Prognóstico de pacientes com câncer criticamente enfermos: passado e presente

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    Dominique D. Benoit

    2008-03-01

    Full Text Available BACKGROUND AND OBJECTIVES: Until the end of the previous century it remained controversial to admit cancer patients to the ICU for advanced-life-supporting therapy. However, over the past few years several centres over the world have shown that it is possible to achieve a meaningful survival in these patients. The aim of this review is to focus on the improvement in outcome that has been achieved over the past two decades in critically ill cancer patients. CONTENTS: We performed a MEDLINE search (period of 1980 to November 2007 to identify full-text English language publications on critically ill patients with solid tumors or hematological malignancies with particular interest for the outcome and treatment. Major MESH search terms included; cancer, solid tumor, hematologic or hematological malignancies, immunosupression, ICU, ventilation, organ failure, sepsis and infection. Additional studies were identified through a manual search of citations from retrieved articles. CONCLUSIONS: In this review, we first focus on the grim prognosis in the past, subsequently we discuss the improvements in outcome over the past few years across subgroups of cancer patients with increasing degree of severity of illness, and finally, we focus on the value of non-invasive ventilation since it is considered the initial ventilatory strategy in these patients.JUSTIFICATIVA E OBJETIVOS: Até o final do século passado, havia grande incerteza quanto a propriedade de internar pacientes com câncer em unidades de terapia intensiva (UTI para medidas de suporte avançado. Contudo, ao longo dos últimos anos, vários centros ao redor do mundo têm reportado aumento significativo da sobrevida de tais pacientes. O objetivo deste estudo foi rever os principais artigos publicados nas duas últimas décadas, com foco na melhoria do prognóstico de pacientes com câncer criticamente enfermos. CONTEÚDO: Realizou-se uma busca bibliográfica no sistema MedLine - PubMed (www

  10. Fatores relacionados ao prognóstico da atresia biliar pós-portoenterostomia Factors related to the post-portoenterostomy prognosis of biliary atresia

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    Jorge Luiz dos Santos

    2002-01-01

    Full Text Available Objetivo: o estudo está envolvido com o prognóstico da atresia biliar pós-portoenterostomia, presença de anomalias congênitas associadas à doença e de malformação de placa ductal, área de fibrose hepática e, sobretudo, com a idade dos pacientes por ocasião da cirurgia. O presente estudo verificou numa amostra de atresia biliar as implicações prognósticas destes fatores. Métodos: foram avaliados 47 pacientes com atresia biliar, em estudo de corte transversal. O material histológico dos casos foi marcado com anticorpo anticitoqueratina 19 e CAM 5.2 por método imunoistoquímico, para o estudo das estruturas biliares, e corado com picrossírius para avaliação da área de fibrose. O estudo das estruturas biliares foi realizado por dois patologistas e pelo primeiro autor deste estudo, "cegos" quanto à evolução dos casos. A mensuração da área de fibrose foi quantitativa. Os dados dos pacientes em relação à idade, ocorrência de óbito ou realização de transplante hepático foram pesquisados nos prontuários. Resultados: a idade por ocasião da portoenterostomia variou entre 24 e 251 dias de vida (90,4 + 44,8 dias, e em 32 casos (72% a evolução pôde ser acompanhada. Os 9 casos (19% com anomalias congênitas extra-hepáticas associadas não diferiram quanto ao prognóstico em relação ao restante da amostra. A idade por ocasião da portoenterostomia influenciou o prognóstico (p=0,016. A área de fibrose foi diferente entre pacientes operados com menos de 60 dias de vida e os operados com mais de 90 dias (p= 0,023, mas não influenciou a evolução dos casos. Tampouco a presença de malformação de placa ductal influiu no prognóstico. Conclusões: a idade por ocasião da portoenterostomia foi o único fator que afetou o prognóstico dos casos de atresia biliar. É necessário maior número de pacientes para avaliar a influência da presença de anomalias congênitas extra-hepáticas associadas sobre a evolução p

  11. Pneumonias e infecção HIV. Algumas particularidades clínicas e factores de prognóstico

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    Jorge T. Monteiro

    1996-03-01

    Full Text Available RESUMO: As pneumonias (PNM constituem uma das principais complicações da infecção HIV. O objectivo deste estudo é comparar 2 grupos de PNM da comunidade internadas na nossa Unidade de Cuidados Intensivos (UCI entre 1990 e 1994: 19 doentes HIV+ (grupo A e 152 doentes HIV- (grupo B. O APACHE II foi semelhante nos 2 grupos. O grupo A. necessitou mais frequentemente de ventilação mecânica (VM (p<0,007 e teve uma P(A-aO2 mais elevada (p<0,004. A acidose metabólica foi também mais frequente neste grupo. Analisando os parâmetros laboratoriais, o grupo A apresentou menor número de linfocitos (p<0,02, DLH mais elevada (p<0,04 e hipoalbuminemia mais marcada (p<0,03. A mortalidade foi maior no grupo A (52,6% do que no grupo B (29,6% (p<0,04. Analisando isoladamente os doentes do grupo A, não encontrámos diferenças significativas entre falecidos e não falecidos, à excepção da hipoalbuminemia, que se correlacionou com a mortalidade (p<0,02. Em conclusão, as PNM dos doentes HIV+ tiveram urn comportamento mais agressivo do que as PNM da comunidade em geral. Na avaliação prognóstica o APACHE II não diferenciou os 2 grupos de PNM. Alguns factores de prognóstico geralmente aceites na análise de PNM oportunistas em doentes HIV+ parecem perder valor em estadios avançados de SIDA, especialmente em doentes necessitando de cuidados intensivos. ABSTRACT: In HIV infections, Pneumonias (PNM have an outstanding place in pulmonary complications. The aim of this work was to compare two groups of patients admitted with PNM in our ICU during the same period (1990-94: Group A, 19 patients HIV+, and Group B, 152 patients HIV-. APACHE II was identical in the 2 groups (p=ns. Group A required more often mechanical ventilation (p<0,007, had a higher P(A-aO2 (p<0,004 and metabolic acidosis was more frequent (p<0,001. Regarding laboratorial parameters Group A had a lower number of linfocytes (p<0,02, a higher LDH (p<0,04 and a more marked hypoalbuminemia (p

  12. Aplicação do prognóstico de deambulação em crianças com paralisia cerebral descrito por Souza e Ferraretto

    OpenAIRE

    Sehoen, Alessandra Cristina Brito; Ricci, Eliane; Oliveira, Weber Gutemberg de

    2008-01-01

    A Paralisia Cerebral como é popularmente conhecida, proporciona as crianças alterações motoras, sensoriais, cognitivas que as fazem apresentar um desenvolvimento diferente das crianças normais. A pesquisa teve como finalidade comprovar a eficácia do prognóstico de deambulação para crianças com Paralisia Cerebral descrita por Souza e Ferraretto. O nosso objetivo foi identificar e comprovar através de pesquisas com cri...

  13. Valor preditivo da distensão de alças intestinais em radiografias no prognóstico de enterocolite necrosante Dilatation of bowel loops on radiological images: prognostic value in necrotizing enterocolitis

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    Daniel Lahan Martins

    2007-10-01

    Full Text Available OBJETIVO: Avaliar o valor prognóstico da distensão de alças intestinais observada em radiografias na evolução e mortalidade de neonatos com enterocolite necrosante. MATERIAIS E MÉTODOS: Nas radiografias de abdome de 53 pacientes obtidas no momento da suspeita diagnóstica de enterocolite necrosante, foi realizada a medida do diâmetro da alça mais distendida (AD, assim como a distância entre a borda superior da primeira vértebra lombar e a borda inferior da segunda (L1-L2, a distância entre as bordas laterais dos pedículos da primeira vértebra lombar (L1, e foram estabelecidas as associações entre AD/L1-L2 e AD/L1. Esta medida foi considerada como possível determinante de potenciais complicações, intervenção cirúrgica e mortalidade. RESULTADOS: Os pacientes que necessitaram de tratamento cirúrgico, aqueles que tiveram complicações durante a evolução e aqueles que morreram da doença tiveram a relação entre AD e AD/L1-L2 maiores (p OBJECTIVE: To evaluate the prognostic value of bowel loops dilatation as a finding on radiographs in the development and mortality of neonates with necrotizing enterocolitis. MATERIALS AND METHODS: On abdominal radiographs of 53 patients for diagnostic suspicion of necrotizing enterocolitis, the major diameters of dilated bowel loops (AD were measured, as well as the distance between the upper border of the first lumbar vertebra and the lower border of the second one (L1-L2, and the distance between the lateral borders of the first lumbar vertebra (L1 pedicles, and the subsequent association between AD/L1-L2, AD/L1. This measure was considered as a possible determining factor for potential complications, surgical intervention and mortality. RESULTS: The patients who needed surgical management and who had complications during progression and died of the disease had showed increased AD and AD/L1-L2 (p < 0.05. AD/L1 values and site of the most dilated bowel loop were not different in the groups

  14. Fatores prognósticos no carcinoma espinocelular de cavidade oral Prognostic factors in squamous cell carcinoma of the oral cavity

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    José Raphael de Moura Campos Montoro

    2008-12-01

    Full Text Available Devido à incerteza da evolução do câncer oral é que os pesquisadores procuram fatores que possam influenciar no prognóstico. OBJETIVO: Avaliar em pacientes com carcinoma espinocelular de cavidade oral variáveis que possam influenciar no tempo de sobrevida. MATERIAIS E MÉTODOS: Analisados dados de 45 pacientes no período de Janeiro de 2001 a Janeiro de 2006. As curvas de sobrevida foram estimadas pelo método de Kaplan-Meier e para compará-las os testes de log-rank e o modelo de regressão de Cox. Desenho do Estudo: Análise retrospectiva. RESULTADOS: A sobrevida global foi de 39% em 5 anos. Apenas as variáveis, metástase cervical (p=0,017, radioterapia pós-operatória (p=0,056 e margens comprometidas (p=0,004 tiveram significância estatística. A sobrevida foi menor em pacientes: com metástase cervical; com margens comprometidas e os submetidos à radioterapia pós-operatória, ou seja, nos tumores mais agressivos. Após ajustamento, a radioterapia não mostrou significância estatística. Provavelmente a sobrevida de 39% seja pelo elevado número de pacientes com metástase (52,2% e pelo fato da amostra ser basicamente de cânceres de língua e assoalho (82%, os de controle mais difícil. CONCLUSÃO: A metástase cervical e o comprometimento das margens cirúrgicas são os fatores prognósticos no carcinoma de cavidade oral que influenciaram na sobrevida.Researchers have been looking for factors that can influence the prognosis of oral cancer, because its outcome is highly uncertain. AIM: To evaluate variables that can impact the survival rate of patients with squamous-cell carcinoma of the oral cavity. MATERIAL AND METHODS: Data analysis of 45 patients from January, 2001 to January, 2006. Survival rate curves have been estimated using the Kaplan-Meier method and they have been compared through the log-rank test and the Cox regression standard. Study design: Retrospective analysis. RESULTS: Total five-year survival rate was of 39

  15. Lactato sérico como marcador prognóstico em crianças gravemente doentes Blood lactate concentration as prognostic marker in critically ill children

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    Adriana Koliski

    2005-08-01

    Full Text Available OBJETIVO: Verificar a utilidade do lactato como marcador de hipoperfusão tecidual e como índice prognóstico em crianças criticamente doentes. MÉTODOS: Estudo prospectivo, longitudinal, tipo observacional de 75 pacientes admitidos na UTI pediátrica do Hospital de Clínicas (UFPR entre novembro de 1998 e maio de 1999. De acordo com o nível de lactato na admissão, os pacientes foram divididos em grupo A (lactato > 18 mg/dl e grupo B (lactato 18 mg/dl evidenciou sinais clínicos de hipoperfusão na admissão. A normalização ou diminuição dos níveis de lactato a partir de 24 horas de internação esteve significativamente relacionada com a maior probabilidade de sobrevida.OBJECTIVE: To assess the use of lactate as a marker of tissue hypoperfusion and as a prognostic index in critically ill patients. METHODS: Prospective, longitudinal, observational study of 75 patients admitted to the pediatric ICU of Hospital de Clínicas of Universidade Federal do Paraná, between November 1998 and May 1999. According to the lactate level on admission, patients were divided into group A (lactate > 18 mg/dl and group B (lactate 18 mg/dl showed clinical signs of hypoperfusion on admission. The normalization or reduction of lactate levels at and after 24 hours of admission was significantly related with higher chances of survival.

  16. Onfalocele: Prognóstico Fetal em 51 Casos com Diagnóstico Pré-Natal Omphalocele: Fetal Prognosis in 51 Cases with Prenatal Diagnosis

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    Samir Aldalla Mustafá

    2001-02-01

    Full Text Available Objetivo: avaliar o prognóstico fetal dos casos de onfalocele com diagnóstico pré-natal. Métodos: foram analisados 51 casos de onfalocele com diagnóstico pré-natal e divididos em 3 grupos: grupo 1, onfalocele isolada; grupo 2, onfalocele com malformações estruturais associadas e cariótipo normal; grupo 3, onfalocele associada à cromossomopatia. As análises foram realizadas em relação à sobrevida geral e pós-correção cirúrgica, considerando as malformações associadas, idade gestacional no parto, peso no nascimento e tamanho da onfalocele. Resultados: o grupo 1 correspondeu a 21% (n = 11, o grupo 2 a 55% (n = 28 e o grupo 3 a 24% (n = 12. Todos os casos do grupo 3 evoluíram para óbito, e a cromossomopatia mais freqüente foi a trissomia do 18. A sobrevida foi de 80% no grupo 1 e de 25% no grupo 2. Dezesseis casos foram submetidos à correção cirúrgica (10 isoladas e 6 associadas e 81% sobreviveram (8 isoladas e 5 associadas. A mediana do peso no nascimento dos sobreviventes pós-correção cirúrgica foi 3.140 g e dos que morreram foi de 2.000 g (p = 0,148 e a idade gestacional do parto foi de 37 e de 36 semanas (p = 0,836, respectivamente. A relação das circunferências onfalocele/abdominal diminuiu com a idade gestacional, 0,88 entre 25-29 semanas e 0,65 entre 30-35 semanas (p = 0,043. Não foi observada diferença significativa no tamanho da onfalocele nos 3 grupos (p = 0,988 e influência deste prognóstico pós-correção cirúrgica (p = 0,553. Conclusão: a sobrevida geral e pós-correção cirúrgica foi de 25 e 81%, respectivamente. As malformações associadas representam o principal fator prognóstico das onfaloceles com diagnóstico pré-natal, visto que se associam com prematuridade e baixo peso.Purpose: to evaluate the prognosis of fetal omphalocele after prenatal diagnosis. Methods: fifty-one cases with prenatal diagnosis of fetal omphalocele were divided into three groups: group 1, isolated omphalocele

  17. Infecções bacterianas pioram o prognóstico da hepatite alcoólica Alcoholic hepatitis: bad prognosis due to concomitant bacterial infections

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    Edna Strauss

    2004-06-01

    Full Text Available As infecções bacterianas cursam com altos índices de morbilidade e mortalidade na cirrose hepática. O objetivo do nosso trabalho foi avaliar se também na hepatite alcoólica as infecções bacterianas são fatores de mau prognóstico. Na avaliação retrospectiva de 681 pacientes hospitalizados em um único centro, por período de 6 anos, foram bem documentados 52 (7,5% casos de hepatite alcoólica, sendo 73,1% com biópsia hepática para análise histopatológica e os restantes por diagnóstico clínico-bioquímico. Houve predomínio do sexo masculino (relação 3,3:1,0, com idade média de 40 anos e ingestão média de etanol puro de 193g/dia por mais de 3 anos. As principais complicações foram: encefalopatia hepática (n=5, insuficiência renal (n=4 e hemorragia digestiva alta (n=3. Houve infecção bacteriana em 11 (21,1% pacientes, sendo pulmonar (n=5, peritonite bacteriana espontânea (PBE (n=2, urinária (n=3 e dermatológica (n=1. Óbito precoce, durante o período de internação ocorreu em 8 (15,4% casos e a análise comparativa entre eles e os sobreviventes mostrou serem fatores de mau prognóstico a presença de encefalopatia hepática (p=0,012, bilirrubinas > 20mg% (p=0,012 e associação com infecções graves (pulmonar/PBE, com p=0,004. Em conclusão, demonstramos que as infecções bacterianas são fatores de mau prognóstico na hepatite alcoólica. Recomendamos, portanto, que a profilaxia com antibióticos que se faz durante hemorragia digestiva alta na cirrose e em casos de insuficiência hepática fulminante, seja estendida para a hepatite alcoólica, em sua forma grave, com finalidade de evitar infecções bacterianas e mortalidade precoce.Bacterial infections increase morbidity and mortality in cirrhosis. Our aim was to investigate whether in alcoholic hepatitis the development of bacterial infections was also a poor prognostic factor. In the retrospective evaluation of 681 hospitalized patients with liver disease

  18. Marcadores morfológicos de prognóstico no mesotelioma maligno: um estudo de 58 casos Morphological aspects as prognostic factors in malignant mesothelioma: a study of 58 cases

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    Alexandre Bottrel Motta

    2006-08-01

    Full Text Available OBJETIVO: Diversos marcadores têm se mostrados promissórios como preditores do diagnóstico e prognóstico do mesotelioma maligno (MM. MÉTODO: Mediante estudo morfométrico e inmunomarcação de componentes estromais (calretinina, CEA, Leu-M1 e trombomodulina e nucleares (p53 e Ki-67, avaliamos a sobrevida após o diagnóstico de 58 pacientes com tumores malignos de pleura. RESULTADOS: O padrão histológico típico do mesotelioma maligno foi encontrado em 50 casos e o padrão atípico em 8 casos. Imunohistoquimicamente foram confirmados 40 casos como sendo mesoteliomas, 11 como adenocarcimonas e 7 casos do padrão atípico não puderam ser classificados. A análise multivariavel do Cox demonstrou a coexistência de um maior fator de risco de morte (476.2, nos pacientes com idade avançada, subtipo histológico bifásico e componentes de expressão nuclear. CONCLUSÃO: A calretinina foi o marcador inmunohistoquímico (IHQ mais útil para o diagnóstico do mesotelioma e o CEA para o de adenocarcinoma. A quantificação por IHQ da trombomodulina foi fundamental na diferenciação do mesotelioma quando este foi positivo tanto para calretinina e como para o CEA. A informação prognostica mais valiosa foi a fornecida pela análise rotineira histopatológica do tipo histológico tumoral. Um ponto importante, divisor natural, foi a idade com uma media de 55 anos e 30.5% de componentes nucleares de marcação IHQ, separando os pacientes em dois grupos: pacientes com uma sobrevivência curta contra pacientes com uma sobrevivência mais longa que a esperada. Assim, a análise histopatológica oferece uma arma poderosa e de elevado potencial para guiar no tratamento adjuvante de quimioterápicos após a retirada cirúrgica do mesotelioma.OBJECTIVE: Various markers have shown promise as diagnostic markers and prognostic predictors in malignant mesothelioma (MM. METHODS: Through morphometric and immunological studies of markers in stromal components

  19. Fatores prognósticos relacionados à falha do tratamento não-operatório de lesões esplênicas no trauma abdominal fechado

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    Fábio Henrique de Carvalho

    Full Text Available OBJETIVO: Identificar fatores prognósticos relacionados com a falha do tratamento não-operatório (TNO de lesões esplênicas no trauma abdominal fechado. MÉTODOS: Análise prospectiva de 56 pacientes adultos submetidos à TNO e divididos em um grupo de sucesso e outro de falha, que foi definida como necessidade de laparotomia por qualquer indicação. As lesões foram diagnosticadas por tomografia computadorizada e classificadas de acordo com os critérios da AAST (American Association for Surgery of Trauma. Os parâmetros estudados foram: na admissão - pressão arterial sistólica, frequências cardíaca e respiratória, nível de consciência (Escala de Glasgow e RTS (Revised Trauma Score; durante a hospitalização - presença de lesões associadas, transfusão sanguínea e parâmetros hematológicos, tempo de internação e ISS (Injury Severity Score. RESULTADOS: As falhas do TNO (19,6% foram devidas à dor abdominal (45,4%, instabilidade hemodinâmica (36,4%, queda do volume globular associada a hematoma esplênico (9,1% e abscesso esplênico (9,1%. Não foram observadas diferenças entre os grupos de sucesso e de falha nos dados na admissão. A taxa de falha de acordo com o grau da lesão esplênica foi 0% nos graus I e II agrupados; 17,5% nos graus III e IV agrupados e 80% no grau V (p = 0,0008. O uso de hemoderivados foi maior e mais frequente no grupo de falha (p=0,05. As relação do ISS (Injury Severity Score com as taxas de falha foram 0% nos pacientes com ISS = 8; 15,9% nos com ISS entre 9 e 25, e 50% nos com ISS = 26 (p = 0,05. Não houve mortalidade e nem lesões de vísceras ocas despercebidas. CONCLUSÃO: O Injury Severity Score e grau da lesão esplênica relacionaram-se com a falha do tratamento não-operatório.

  20. Prognóstico visual de 'crosslinking' para ceratocone com base em tomografia de córnea pré-operatória

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    Lopes Bernardo

    2014-08-01

    Full Text Available Objetivo: Verificar índices tomográficos do pré-operatório de pacientes com ceratocone submetidos à crosslinking corneano (CXL como fatores preditivos para a melhora na acuidade visual corrigidas (AVc após um ano. Métodos: Estudo retrospectivo que incluiu 63 olhos de 53 pacientes com ceratocone progressivo submetidos à CXL segundo o protocolo de Dresden: deseptelização corneana, riboflavina 0,1% por 30 minutos e luz ultra-violeta A (UVA a uma irradiância de 3mW/cm2 por 30 minutos. Foram avaliados exames de tomografia corneana com sistema de Scheimpflug rotacional (Pentacam, Oculus antes do CXL e a acuidade visual corrigida antes e após a cirurgia. A análise estatística foi feita com o teste de Kolmorov-Smirnov, teste t de student e curvas de característica operador-receptor (ROC. Resultados: Houve diferença estatisticamente significante (p<0,05 entre os pacientes que obtiveram melhora de AVc em um ano e os que não experimentaram melhora na AVc nesse período nos índices tomográficos pré-operatórios relacionados com espessura e volume corneano. Entre os pacientes que obtiveram melhora na AVc todos possuíam volume corneano em 6,0mm maior que 14,55mm3 e 97,2% deles possuíam volume corneano em 6,5mm maior que 17,76mm3. Assim como, 94,29% desses pacientes apresentavam paquimetria média em 4,0mm maior que 487 μm e 82,86% paquimetria no ponto mais fino maior de 421 μm. Conclusão: Pacientes com ceratocone menos avançado (volume e espessura da córnea maiores no período pré-operatório obtiveram mais chances de ter melhora da AVc um ano após CXL. Estudos prospectivos envolvendo outras variáveis relacionadas com a aberrometria total e o estudo biomecânico da córnea são relevantes para se aumentar a capacidade prognóstica do resultado após CXL.

  1. Peso do baço como fator prognóstico do tratamento cirúrgico de pacientes portadores de esquistossomose mansônica

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    Álvaro Antônio Bandeira Ferraz

    Full Text Available OBJETIVO: Analisar pré-operatoriamente o peso do baço como fator prognóstico do tratamento cirúrgico de pacientes portadores de esquistossomose mansônica. MÉTODOS: Foram analisados 114 pacientes, portadores de esquistossomose mansônica com antecedentes de hemorragia digestiva, submetidos a tratamento cirúrgico. Os pacientes foram divididos em três grupos: Grupo 1 - baço menor que 500 gramas (17; Grupo 2 - baço entre 500 e 1.000 gramas (58; Grupo 3 - baço acima de 1.000 gramas (39. RESULTADOS: No Grupo 1 a recidiva hemorrágica foi de 17,6%, trombose da veia porta de 5,9% e não houve mortalidade. A incidência de hiperesplenismo pré-operatório foi de 29,4% e o calibre da veia porta foi de 1,1cm. No Grupo 2 a recidiva hemorrágica foi de 15,5%, trombose da veia porta de 10,3% e a mortalidade de quatro pacientes (6,9% (dois pacientes no período pós-operatório e dois no seguimento tardio, hepatocarcinoma e hemorragia digestiva. A incidência de hiperesplenismo foi de 53,4% e o calibre médio da veia porta foi de 1,4cm. No Grupo 3 a recidiva hemorrágica foi de 12,8%, trombose da veia porta de 5,1% e uma mortalidade tardia de dois pacientes (linfoma e infarto agudo do miocárdio. A incidência de hiperesplenismo foi de 76,9% e o calibre da veia porta foi de 1,5cm. CONCLUSÕES: O peso do baço apresenta relação com o hiperesplenismo pré-operatório, calibre da veia porta e permanência hospitalar pós-operatória. Não encontramos relação com a incidência de varizes de fundo gástrico, recidiva de sangramento digestivo, trombose da veia porta, grau de fibrose periportal e dados bioquímicos.

  2. Information

    International Nuclear Information System (INIS)

    Boyard, Pierre.

    1981-01-01

    The fear for nuclear energy and more particularly for radioactive wastes is analyzed in the sociological context. Everybody agree on the information need, information is available but there is a problem for their diffusion. Reactions of the public are analyzed and journalists, scientists and teachers have a role to play [fr

  3. O papel da neutropenia no prognóstico do doente oncológico com pneumonia adquirida na comunidade

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    S. Aliberti

    2009-07-01

    especialistas. Assim, os clínicos podiam sentir-se confiantes e tratar a PAC no doente oncológico não neutropénico como na população geral.No entanto, o papel da neutropenia no prognóstico de doentes neoplásicos hospitalizados com PAC não tinha, ainda, sido investigadoO objectivo do presente estudo foi comparar o prognóstico de doentes neoplásicos e doentes imunocompetentes com PAC, bem como o prognóstico de indivíduos com patologia maligna e neutropenia absoluta ou funcional e sem neutropenia.Foi efectuada uma análise retrospectiva envolvendo 43 hospitais em 12 países no período compreendido entre Junho de 2001 e Janeiro de 2006. Foram incluídos os indivíduos com idade ≥ 18 anos com critérios de PAC, tendo sido eliminados os portadores de infecção VIH. A PAC foi definida pela presença de infiltrado pulmonar “de novo” na radiografia do tórax na altura do internamento, associado a, pelo menos, um dos seguintes parâmetros: tosse ou aumento da intensidade desta; tax 37,8°C; número de leucócitos no sangue periférico (leucocitose, desvio esquerdo ou leucopenia.Neoplasia foi definida como qualquer tipo de malignidade diagnosticada nos 12 meses anteriores ou neoplasia activa. Considerou-se que esta estaria presente em doentes sob quimioterapia e/ou radioterapia nos 12 meses precedentes ou com sinais ou sintomas de neoplasia ao longo do último ano. Doentes com neoplasia de células escamosas ou basais da pele foram consideradas imunocompetentes.A neutropenia foi classificada como funcional ou absoluta. A primeira estava presente em doentes com doença hematológica maligna. A neutropenia absoluta correspondeu a um número de neutrófilos <500cel//mm3 na admissão hospitalar.Os doentes com PAC foram divididos em dois grupos: doentes não oncológicos – Grupo I, e doentes com neoplasia – Grupo II. Este último foi, por seu turno, subdividido em dois subgrupos

  4. O valor prognóstico da telerradiografia de tórax na cardiomiopatia dilatada idiopática na infância

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    Azevedo Vitor M. P

    2004-01-01

    Full Text Available OBJETIVOS: Analisar o valor prognóstico da cardiomegalia, da congestão pulmonar e do índice cardiotorácico como marcadores de óbito e sobrevida em crianças com cardiomiopatia dilatada. MÉTODOS: Estudo retrospectivo de 152 pacientes entre setembro de 1979 e março de 2003. Foram realizados 722 exames nos primeiros 72 meses e 100 nos primeiros 15 dias de evolução. Análise estatística: qui-quadrado, teste t de Student, análise de variância para medidas repetidas e método de Kaplan-Meier. Foram utilizados os valores alfa = 0,05 e beta = 0,80. RESULTADOS: Idade no diagnóstico de 2,2±3,2 anos. Incidência maior nos menores de 2 anos (76,3%; IC 95% = 68,7% a 82,8% (p < 0,0001. Sexo (p = 0,07 e etnia (p = 0,11 não foram significantes, e a mortalidade não foi influenciada pela faixa etária (p = 0,73, sexo (p = 0,78 e etnia (p = 0,20. A maioria dos pacientes (84,2%; IC 95% = 77,4% a 89,6% era grave, classe funcional III e IV (p < 0,0001, e todos os 43 óbitos ocorreram neste grupo (p = 0,0008. Cardiomegalia inicial foi observada em 94,1% (IC 95% = 89,1% a 97,2% (p < 0,0001 e congestão pulmonar em 75,6% (IC 95% = 68,0% a 82,2%(p < 0,0001, sendo mais freqüente na classe funcional III/IV (RC = 8,03; IC 95% = 2,85% a 23,1%(p < 0,0001. A congestão pulmonar foi marcadora de óbito (RC = 3,16; IC 95 %= 1,06% a 10,07 (p = 0,0222, o mesmo não ocorrendo com a cardiomegalia (p = 0,1185. A sobrevida foi influenciada pela cardiomegalia (p = 0,0189 e pela congestão pulmonar (p = 0,0050. O índice cardiotorácico máximo e médio foram superiores no grupo óbito (0,749+0,053 versus 0,662+0,080 (p < 0,0001 e (0,716+0,059 versus 0,620+0,085 (p < 0,0001. A análise de variância demonstrou diminuição progressiva do índice cardiotorácico no grupo que sobreviveu (p < 0,0001. CONCLUSÃO: Em crianças com diagnóstico de cardiomiopatia dilatada Idiopática, a presença de congestão pulmonar no exame inicial e o aumento do índice cardiotorácico, s

  5. Gastrosquise: Diagnóstico Pré-natal x Prognóstico Neonatal Gastroschisis: Prenatal Diagnosis x Neonatal Outcome

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    Melania Maria Ramos de Amorim

    2000-05-01

    Full Text Available Objetivos: determinar a freqüência de diagnóstico pré-natal em recém-nascidos (RN com gastrosquise operados no Instituto Materno-Infantil de Pernambuco (IMIP e analisar suas repercussões sobre o prognóstico neonatal. Métodos: realizou-se um corte transversal retrospectivo incluindo 31 casos de gastrosquise submetidos a correção cirúrgica em nosso serviço entre 1995-1999. Calculou-se o risco de prevalência (RP de morte neonatal e seu intervalo de confiança a 95% para a presença de diagnóstico pré-natal e outras variáveis cirúrgicas e perinatais, realizando-se análise de regressão logística múltipla para determinação do risco ajustado de morte neonatal. Resultados: apenas 10 (32,3% dos 31 casos de gastrosquise tinham diagnóstico pré-natal e nasceram no IMIP. Nenhum RN com diagnóstico pré-natal foi prematuro, em contraste com 43% daqueles sem diagnóstico pré-natal (p 4 horas, cirurgia em estágios, necessidade de ventilação mecânica e infecção. Conclusões: o diagnóstico pré-natal foi infreqüente entre RN com gastrosquise e a morte neonatal foi extremamente alta em sua ausência. É necessário aumentar a freqüência de diagnóstico pré-natal e melhorar os cuidados perinatais para reduzir esta elevada mortalidade.Purpose: to determine the frequency of prenatal diagnosis in newborns with gastroschisis operated at the Instituto Materno-Infantil de Pernambuco (IMIP and to analyze its repercussions on neonatal prognosis. Patients and Methods: a cross-sectional study was carried out, including 31 cases of gastroschisis submitted to surgical correction in our service from 1995 to 1999. Prevalence risk (PR of neonatal death and its 95% confidence interval were calculated for the presence of prenatal diagnosis and other perinatal and surgical variables. Multiple logistic regression analysis was carried out to determine the adjusted risk of neonatal death. Results: only 10 of 31 cases of gastroschisis (32.3% had

  6. Decompressive craniotomy: prognostic factors and complications in 89 patients Craniotomia descompressiva: análise de fatores prognósticos e complicações em 89 pacientes

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    Rodrigo Moreira Faleiro

    2008-06-01

    Full Text Available Decompressive craniotomy (DC is applied to treat post-traumatic intracranial hypertension (ICH. The purpose of this study is to identify prognostic factors and complications of unilateral DC. Eighty-nine patients submited to unilateral DC were retrospectively analyzed over a period of 30 months. Qui square independent test and Fisher test were used to identify prognostic factors. The majority of patients were male (87%. Traffic accidents had occurred in 47% of the cases. 64% of the patients had suffered severe head injury, while pupillary abnormalities were already present in 34%. Brain swelling plus acute subdural hematoma were the most common tomographic findings (64%. Complications occurred in 34.8% of the patients: subdural effusions in 10 (11.2%, hydrocephalus in 7 (7.9% and infection in 14 (15.7%. The admittance Glasgow coma scale was a statistically significant predictor of outcome ( p=0.0309.A craniotomia descompressiva (CD é técnica utilizada para tratamento da hipertensão intracraniana (HIC pós-traumática. O objetivo do estudo foi determinar fatores prognósticos e complicações nos pacientes submetidos a esta técnica. Realizou-se estudo retrospectivo de 89 pacientes submetidos à CD unilateral para tratamento da HIC pós-traumática durante 30 meses. Utilizou-se testes do Qui-quadrado de independência e teste exato de Fisher para análise de fatores independentes de prognóstico. A maioria dos pacientes era do sexo masculino (87%. A causa mais comum foi o acidente de trânsito (47%. A maioria apresentava traumatismo cranioencefálico grave (64%, 34% já apresentavam anisocoria. O achado tomográfico mais comum foi a associação entre tumefação cerebral e hematoma subdural agudo (64%. Em 34,8% dos pacientes houve complicações inerentes à técnica: coleção subdural (11,2%, hidrocefalia (7,9% e infecção (15,7%. A escala de coma de Glasgow à admissão correlacionou-se estatisticamente como fator prognóstico (p=0,0309.

  7. Monitorização do sistema nervoso autônomo em ambiente de cuidados intensivos como ferramenta de prognóstico. Revisão sistemática

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    Luis Bento

    Full Text Available RESUMO Objetivo: Apresentar uma revisão sistemática do uso da monitorização do sistema nervoso autônomo como ferramenta de prognóstico, verificando a variabilidade da frequência cardíaca nas unidades de cuidados intensivos. Métodos: Revisão de literatura publicada até julho de 2016 na PubMed/MEDLINE de estudos realizados em unidades de cuidados intensivos, sobre a monitorização do sistema nervoso autônomo, por meio da análise da variabilidade da frequência cardíaca, como ferramenta de prognóstico - estudo da mortalidade. Foram utilizados os seguintes termos em inglês no campo de pesquisa: ("autonomic nervous system" OR "heart rate variability" AND ("intensive care" OR "critical care" OR "emergency care" OR "ICU" AND ("prognosis" OR "prognoses" OR "mortality". Resultados: A probabilidade de morte nos doentes aumentou com a diminuição da variabilidade da frequência cardíaca, estudada por meio da variância da frequência cardíaca, desacoplamento cardíaco, volatilidade da frequência cardíaca, integer heart rate variability, desvio padrão de todos os intervalos RR normais, raiz quadrada da média do quadrado das diferenças entre intervalos RR adjacentes, poder total, componente de baixa frequência, componente de muito baixa frequência, razão entre o componente de baixa frequência e o componente de alta frequência, razão entre expoentes fractais de curto e longo prazo, entropia de Shannon, entropia multiescalar e entropia aproximada. Conclusão: Nos doentes internados em unidades de cuidados intensivos, independentemente da patologia que motivou o internamento, a variabilidade da frequência cardíaca varia de forma inversa com a gravidade clínica e com o prognóstico.

  8. Valor prognóstico da variabilidade da frequência cardíaca e da eletrocardiografia ambulatorial em cães Boxer com cardiomiopatia arritmogênica do ventrículo direito

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    P.P.C. Chamas

    Full Text Available RESUMO A cardiomiopatia arritmogênica do ventrículo direito (CAVD é uma importante causa de morte súbita em cães da raça Boxer. A validação de fatores prognósticos para essa doença auxiliaria na detecção de animais mais gravemente afetados e sua exclusão dos programas de reprodução. O objetivo deste estudo foi avaliar o valor prognóstico da presença de manifestações clínicas, dos índices de variabilidade de frequência cardíaca (VFC e das arritmias supraventriculares ou ventriculares registradas à monitorização eletrocardiográfica com Holter na sobrevida de cães Boxer em diferentes estágios da CAVD. Essas variáveis foram analisadas, de forma prospectiva, em 69 cães Boxer, divididos em cinco grupos: cães Boxer controle (grupo CB, 300 VPC/24 horas, n=19, cães Boxer com CAVD e disfunção sistólica sem insuficiência cardíaca congestiva (grupo SDB sem ICC, n=6 e com ICC (grupo SDB com ICC, n=8. A análise estatística compreendeu teste ANOVA, correlação de Pearson e análise de riscos proporcionais de Cox. Comparando-se com o grupo CB, não foi encontrada diminuição nos índices de VFC nos grupos SB, ARVC ou SDB sem ICC; por outro lado, o grupo SDB com ICC apresentou diminuição desses índices. Não houve relação entre os índices de VFC e a morte de origem cardíaca; porém, a presença de síncopes com ou sem sinais clínicos de ICC e o número de episódios de taquicardia ventricular (TV correlacionaram-se com a sobrevida dos animais. Estes resultados permitem concluir que a presença de sinais clínicos de ICC, a presença de síncopes e o número de TV ao Holter apresentam valor prognóstico de sobrevida em cães Boxer com CAVD.

  9. Informe

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    Egon Lichetenberger

    1950-10-01

    Full Text Available Informe del doctor Egon Lichetenberger ante el Consejo Directivo de la Facultad, sobre el  curso de especialización en Anatomía Patológica patrocinado por la Kellogg Foundation (Departamento de Patología

  10. Rana catesbeiana, pólvora e modulação supramolecular cicatrização intestinal e prognóstico no câncer de cólon: uma mesma origem biológica para o insucesso? Rana catesbeiana, Gunpowder and Supramolecular Modulation Intestinal Healing and Prognosis in Colon Cancer: The Same Biological Origin of the Failure?

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    Edna Delabio-Ferraz

    2010-06-01

    Full Text Available A cicatrização e remodelação do cólon resultam das modificações do colágeno na matriz extracelular. Algumas condições desequilibram sua renovação, enfraquecendo a resistência mecânica a cicatriz, como resultado da atividade elevada das metaloproteinases locais, e levando a um alto risco de deiscência. As metaloproteinases da matriz extracelular (matrix metalloproteinases, MMPs constituem uma família de endopeptidases zinco-dependentes - metzincinas. São reconhecidos atualmente, em humanos, cerca de 24 genes responsáveis por cada uma delas. A colagenase (MMP-1 foi identificada por Gross e Lapière (1962 na cauda do girino da rã-touro americana. No câncer as MMPs tem ocupado um lugar especial. Evidências de que a célula neoplásica é capaz de interferir na modulação desta enzima - um co-fator associado à invasividade local e disseminação metastática. As MMP-2 e -7 são observadas com frequência no câncer de cólon, a MMP-12 parece exercer um efeito protetor (melhor prognóstico e, ao contrário, a MMP-3 o torna pior. A associação entre alta atividade de MMPs, o pior prognóstico do câncer e o maior risco de deiscência de anastomose intestinal já vem sendo considerada, sugerindo uma trilogia consistente. A terapia farmacológica (inibidores MMPs tem sido investigada, também para o controle do câncer. O artigo discute as informações mais relevantes e atualizadas sobre o assunto.Colon healing and remodeling depends on the collagen changes in extracellular matrix. Some conditions, disrupt its turnover, causing strength weakening of the scar, as a result of high activity of local matrix metalloproteinases, causing a high risk of dehiscence. The extracellular matrix metalloproteinases are a family of zinc-dependent endopeptidases, or metzincines, and have been currently recognized in humans about 24 genes responsible for each one. The first MMP, colagenase (MMP-1, was described by Gross and Lapière (1962, while

  11. Prognostic factors predicting a fatal outcome in HIV-negative children with neurotuberculosis Fatores prognósticos de letalidade da neurotuberculose em crianças HIV-negativas

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    Murilo Gimenes Rodrigues

    2010-10-01

    Full Text Available OBJECTIVE: To identify prognostic factors predicting a fatal outcome in HIV-negative children with neurotuberculosis based on clinical, epidemiological, and laboratory findings. METHOD: The clinical records of all in-patients diagnosed with neurotuberculosis from 1982 to 2005 were evaluated retrospectively. The following prognostic parameters were examined: gender, age, close contact with a tuberculosis-infected individual, vaccination for bacillus Calmette-Guérin, purified protein derivative (PPD of tuberculin results, concomitant miliary tuberculosis, seizures, CSF results, and hydrocephalus. RESULTS: One hundred forty-one patients diagnosed with neurotuberculosis were included. Seventeen percent of the cases resulted in death. The factors that were correlated with a negative outcome included lack of contact with a tuberculosis-infected individual, negative PPD reaction, coma, and longer hospitalisation time. A multiple logistic regression analysis was performed to identify which of these factors most often resulted in death. CONCLUSION: Coma at diagnosis, lack of tuberculosis contact, and a non-reactive PPD were the most important predictors of fatality in patients with neurotuberculosisOBJETIVO: Identificar elementos prognósticos para a letalidade da neurotuberculose na criança, a partir das manifestações clínicas, dados epidemiológicos e laboratoriais. MÉTODO: Registros de pacientes internados durante o período de 1982 a 2005 foram retrospectivamente avaliados. Os elementos prognósticos considerados foram: sexo, idade, história de contato íntimo com indivíduo com tuberculose, vacinação com o bacilo de Calmette-Guérin (BCG, teste tuberculínico (PPD, concomitância de tuberculose miliar, convulsões, resultados da análise do LCR e presença de hidrocefalia. RESULTADOS: 141 pacientes com diagnóstico de neurotuberculose foram incluídos. Dezessete por cento dos pacientes foram a óbito. Os fatores associados ao óbito foram

  12. Os familiares cuidadores da criança com doença de mau prognóstico : fundamentos para uma intervenção no âmbito dos cuidados paliativos

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    Ramos, Sílvia da Encarnação de Barros, 1971-

    2007-01-01

    Tese de mestrado em Cuidados Paliativos, apresentada à Faculdade de Medicina da Universidade de Lisboa, 2007 A notícia de uma doença de mau prognóstico na criança é sem dúvida um dos acontecimentos mais dramáticos da vida de uma família pois a doença grave constitui para todos os seus membros uma surpresa dolorosa, um golpe difícil de suportar que poderá pôr à prova os valores em que se baseia a família, a solidez dos laços afectivos entre os seus membros, a união e a solidariedade entre t...

  13. Significado prognóstico do linfonodo metastático N3 em carcinomas epidermóides de cabeça e pescoço

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    Amar,Ali; Curioni,Otávio Alberto; Rapoport,Abrão

    2004-01-01

    OBJETIVO: Avaliar os resultados do tratamento da doença metastática em estádio avançado (N3) e sua relação com o prognóstico do carcinoma espinocelular de cabeça e pescoço. MÉTODO: Foram revisados as informações de prontuários de 241 pacientes, com carcinoma espinocelular de boca, orofaringe, laringe e hipofaringe com metástases cervicais maiores que 6 cm (N3) submetidos à cirurgia e/ou radioterapia, no Departamento de Cirurgia de Cabeça e Pescoço e Otorrinolaringologia do Hospital Heliópolis...

  14. Fatores prognósticos para o parto transvaginal em pacientes com cesárea anterior Prognostic factors for vaginal delivery after cesarian section

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    Luiz Carlos Santos

    1998-07-01

    Full Text Available O objetivo deste estudo foi determinar os fatores prognósticos para a ultimação do parto por via transpélvica em gestantes com cesárea anterior admitidas em trabalho de parto no CAM-IMIP. Foi realizado um estudo tipo caso-controle, analisando os partos de pacientes com cesárea prévia assistidos no CAM-IMIP no período de janeiro/1991 a dezembro/1994. Foram considerados casos as pacientes com cesárea anterior (n=156 e controles as que tiveram parto transvaginal (n=338. Os critérios de inclusão foram: idade gestacional > 36 semanas, cesárea anterior há pelo menos 1 ano, concepto vivo, trabalho de parto espontâneo e apresentação cefálica fletida. Foram excluídas as gestações de alto risco, os casos de sofrimento fetal anteparto e pacientes com história de parto transpélvico anterior depois da cesárea. A análise estatística foi realizada em Epi-Info 6.0 e Epi-Soft, utilizando-se os testes chi² de associação, teste exato de Fisher e "t" de Student, bem como a odds ratio e seu intervalo de confiança a 95%. Análise de regressão logística múltipla foi efetuada para controle das variáveis confundidoras. O percentual de cesáreas no grupo estudado foi de 31,6%. Os fatores maternos que apresentaram associação significativa com o parto transvaginal foram a idade materna 35 anos (OR = 0,54, IC a 95% = 0,36-0,82, a história de parto vaginal anterior (OR = 1,6, IC a 95% = 1,01-2,55 e a indicação da cesárea anterior por doenças da gestação (OR = 3,67, IC a 95% = 1,19-12,02. Fatores como intervalo entre a cesárea anterior e o parto atual, outras indicações de cesárea e o tipo de histerorrafia não apresentaram associação significativa com o parto transpélvico. No modelo de regressão logística múltipla, persistiram como variáveis associadas significativamente ao parto vaginal a idade materna e a história de parto vaginal anterior. Os autores concluíram que sendo a idade materna Objectives: to determine

  15. Prognóstico de pacientes com tumor de Wilms unilateral no Rio de Janeiro, 1990-2000 Prognosis for patients with unilateral Wilms' tumor in Rio de Janeiro, Brazil, 1990-2000

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    Marilia Fornaciari Grabois

    2005-10-01

    Full Text Available OBJETIVO: Analisar a sobrevida e os principais fatores prognósticos entre os pacientes com tumor de Wilms unilateral. MÉTODOS: A coorte de estudo incluiu 132 casos de tumor de Wilms unilateral em menores de 15 anos de idade matriculados em serviço de oncologia pediátrica, de janeiro de 1990 a dezembro de 2000. Curvas de sobrevida foram confeccionadas utilizando-se o método de Kaplan-Meier e fatores prognósticos foram analisados pelo modelo de riscos proporcionais de Cox. RESULTADOS: A estimativa de sobrevida global em cinco anos foi 84,6%. As probabilidades de sobrevida para os estádios I, II, III e IV foram de 100%; 94,2%; 83,2% e 31,3%, respectivamente. A taxa de sobrevida para os pacientes com: histologia favorável foi de 89,4%, para aqueles com anaplasia focal 66,7 % e com anaplasia difusa 40%. Todos os pacientes com doença em estádio IV e anaplasia difusa foram a óbito (n=4. Todos os pacientes com doença em estádio I, independente da histologia, permaneceram vivos até o final do período de seguimento. CONCLUSÕES: Entre as variáveis escolhidas para o modelo final apenas o estadiamento e a histologia permaneceram associados ao elevado risco de óbito enquanto que os casos na faixa etária entre 24 e 47 meses apresentaram melhor prognóstico que os demais. Esses resultados mostram a importância do diagnóstico em fases iniciais da doença e que a histologia é fundamental para orientar a terapia adequada.OBJECTIVE: To analyze the survival and the main prognostic factors among patients with unilateral Wilms' tumor patients. METHODS: The study cohort included 132 patients with unilateral Wilms' tumor aged under 15 years, who were enrolled in a pediatric oncology service. Survival curves were calculated using the Kaplan-Meier method and the prognostic factors were analyzed using the Cox proportional hazards model. RESULTS: The overall survival rate for five years was 84.6%. The survival probabilities for disease in stages I, II

  16. Fatores prognósticos de sobrevida pós-reanimação cardiorrespiratória cerebral em hospital geral In-hospital post-cardiopulmonary-cerebral resuscitation survival prognostic factors

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    André Mansur de Carvalho Guanaes Gomes

    2005-10-01

    Full Text Available OBJETIVO: Analisar as características clínicas e demográficas dos pacientes que receberam reanimação cardiorrespiratória e detectar fatores prognósticos de sobrevivência a curto e longo prazo. MÉTODOS: Analisamos, prospectivamente, 452 pacientes que receberam reanimação em hospitais gerais de Salvador. Utilizou-se análise uni, bivariada e estratificada nas associações entre as variáveis e a curva de sobrevida de Kaplan-Meier e a regressão de Cox para análise de nove anos de evolução. RESULTADOS: A idade variou de 14 a 93 anos, media de 54,11 anos; predominou o sexo masculino; metade dos pacientes tinha ao menos uma doença de base, enfermidade cardiovascular foi etiologia responsável em metade dos casos. Parada cardíaca foi testemunhada em 77% dos casos e em apenas 69% dos pacientes foi iniciada imediatamente a reanimação. O ritmo cardíaco inicial não foi diagnosticado em 59% dos pacientes. Assistolia foi o ritmo mais freqüente (42%, seguida de arritmia ventricular (35%. A sobrevida imediata foi de 24% e sobrevida à alta hospitalar de 5%. Foram identificados como fatores prognósticos em curto prazo: etiologia da parada; diagnóstico do ritmo cardíaco inicial; fibrilação ou taquicardia ventricular como mecanismo de parada; tempo estimado préreanimação menor ou igual a 5 minutos e, tempo de reanimação menor ou igual a 15 minutos. Os fatores prognósticos de sobrevivência em nove anos de evolução foram: não ter recebido epinefrina; ser reanimado em hospital privado e tempo de reanimação menor ou igual a 15 minutos. CONCLUSÃO: Os dados observados podem servir de subsídios para os profissionais de saúde decidir quando iniciar ou parar uma reanimação no ambiente hospitalar.OBJECTIVE: To assess clinical and demographic characteristics of patients who had cardiopulmonary resuscitation and identify short- and long-term survival prognostic factors. METHODS: Four hundred and fifty-two (452 resuscitated

  17. Significado prognóstico dos graus histológicos do linfoma de Hodgkin do tipo esclerose nodular Prognostic significance of histopathological grading of nodular sclerosing Hodgkin’s lymphoma

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    Luís Fernando Pracchia

    2005-10-01

    Full Text Available INTRODUÇÃO: A esclerose nodular (EN, do tipo histológico freqüente do linfoma de Hodgkin (LH, apresenta grande variabilidade em sua composição celular. Na década de 80, pesquisadores do British National Lymphoma Investigation (BNLI propuseram uma subclassificação histológica do LH EN. Eles identificaram dois graus histológicos - o LH EN grau I (LH EN I e o LH EN grau II (LH EN II - e demonstraram que os portadores de LH EN II apresentavam menor sobrevida em comparação aos portadores de LH EN I. Outros estudos, entretanto, não reproduziram esses achados. OBJETIVO: Avaliar o significado prognóstico da graduação histológica proposta pelo BNLI. MATERIAIS E MÉTODOS: Estudo retrospectivo que incluiu 69 casos de LH EN. Mais de 90% dos casos foram tratados com terapia combinada ou quimioterapia exclusiva, não havendo diferença no tipo de tratamento oferecido a depender do grau histológico. RESULTADOS: Trinta e cinco casos (51% foram classificados com EN I e 34 (49% como EN II. Não observamos diferenças na distribuição de outros fatores prognósticos entre os portadores dos dois graus. Remissão completa após o tratamento inicial foi obtida em 85,7% dos casos de EN I e em 82,4% dos casos de EN II (p = 0,75. A probabilidade estimada de sobrevida global em cinco anos foi de 67% para EN I e de 83,5% para EN II (p = 0,13 e a taxa de sobrevida livre de doença em cinco anos foi de 85,2% versus 87%, respectivamente (p = 0,72. CONCLUSÃO: Nesta população de pacientes uniformemente tratados a graduação histológica BNLI não esteve associada com o prognóstico do LH EN.BACKGROUND: Nodular sclerosis (NS, a frequent histological subtype of Hodgkin’s lymphoma (HL, presents great variability in its cellular composition. In the 80's, researchers of the British National Lymphoma Investigation (BNLI proposed a histological-based subclassification for NS HL. They identified two histological grades - NS HL grade I (NS HL I and NS HL grade

  18. Avaliação prognóstica da doença coronária estável através de um novo escore

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    Fernanda Coutinho Storti

    2011-05-01

    Full Text Available FUNDAMENTO: A necessidade de melhorar a acurácia do teste de esforço, determinou o desenvolvimento de escores, cuja aplicabilidade já foi amplamente reconhecida. OBJETIVO: Avaliação prognóstica do coronariopata estável através de um novo escore simplificado. MÉTODOS: Um novo escore foi aplicado em 372 coronariopatas multiarteriais e função ventricular preservada, 71,8% homens, idade média 59,5 (± 9,07 anos, randomizados para angioplastia, revascularização cirúrgica e tratamento clínico, acompanhados por 5 anos. Óbito cardiovascular foi o desfecho primário. Infarto do miocárdio não-fatal, óbito e re-intervenção formaram o desfecho combinado secundário. O escore baseou-se numa equação previamente validada resultante da soma de 1 ponto para: sexo masculino, história de infarto, angina, diabete, uso de insulina e ainda 1 ponto para cada década de vida a partir dos 40 anos. Teste positivo adicionou 1 ponto. RESULTADOS: Ocorreram 36 óbitos (10 no grupo angioplastia, 15 no grupo revascularização e 11 no grupo clínico, p = 0,61. Observou-se 93 eventos combinados: 37 no grupo angioplastia, 23 no grupo revascularização e 33 no grupo clínico (p = 0,058. 247 pacientes apresentaram escore clínico > 5 pontos e 216 > 6 pontos. O valor de corte > 5 ou > 6 pontos identificou maior risco, com p = 0,015 e p = 0,012, respectivamente. A curva de sobrevida mostrou uma incidência de óbito após a randomização diferente naqueles com escore > 6 pontos (p = 0,07, e uma incidência de eventos combinados diferente entre pacientes com escore 6 pontos (p = 0,02. CONCLUSÃO: O novo escore demonstrou consistência na avaliação prognóstica do coronariopata estável multiarterial.

  19. Guillain-Barré syndrome in the elderly: clinical, electrophysiological, therapeutic and outcome features Síndrome de Guillain-Barré no idoso: aspectos clínico-eletrofisiológicos, terapêutico e prognóstico

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    Marcondes C. França Jr

    2005-09-01

    Full Text Available There are few papers devoted to geriatric Guillain-Barré (GBS and many related issues remain unanswered. OBJECTIVE: To describe clinical, electrophysiological and therapeutic features in this age. METHOD: Clinico-epidemiological data and therapy of GBS patients older than 60 years were reviewed. Hughes scores were used to quantify neurological deficit and define outcome. RESULTS: Among 18 patients (mean age 64.8 years, 9 had evident prodrome and 80% noticed initially sensory-motor deficit. Demyelinating GBS was found in 8 and axonal in 6 subjects. There was one Miller-Fisher and 3 unclassified cases. Plasmapheresis (PFX was single therapy in 12 patients and intravenous immunoglobulin (IVIg in 2. Disability scores just before therapy were similar in both groups, so as short and long term outcome. CONCLUSION: Axonal GBS seems to be more frequent in the elderly and this may have prognostic implications. PFX and IVIg were suitable options, but complications were noticed with PFX. Prospective studies are needed to better understand and manage GBS in the elderly.Publicações sobre a síndrome de Guillain-Barré (SGB no idoso são escassas e várias questões sobre o tema estão abertas. OBJETIVO: Descrever aspectos clínico-eletrofisiológicos, terapêuticos e prognóstico no idoso. MÉTODO:Revisamos os prontuários de pacientes acima de 60 anos com SGB. A escala de Hughes foi usada para quantificar os déficits iniciais e finais. RESULTADOS: No total de 18 pacientes (média de idade 64,8 anos, 50% tiveram pródromo e 80% tiveram déficit sensitivo-motor no início. SGB desmielinizante foi encontrada em 8 pacientes, axonal em 6 e uma síndrome de Miller-Fisher. Três casos não puderam ser classificados. Plasmaférese (PFX foi empregada isoladamente em 12 pacientes e imunoglobulina endovenosa (IVIg em 2. A disfunção inicial nos dois grupos tratados era semelhante, assim como a evolução a curto e longo prazo. CONCLUSÃO: A forma axonal da SGB

  20. Estudo citofotométrico da expressão do marcador tumoral Fator VIII e fatores prognósticos no adenocarcinoma gástrico Cytophotometric study of the expression of the tumoral marker Factor VIII and prognostic factors in gastrci adenocarcinoma

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    Mary Tossa Nakamura

    2007-12-01

    Full Text Available RACIONAL: No câncer gástrico, a incidência, o diagnóstico e as opções terapêuticas apresentaram melhorias nas últimas décadas, porém o prognóstico permanece reservado, especialmente devido à maioria dos pacientes procurarem recurso médico com tumores avançados, metastáticos ou cirurgicamente irressecáveis já no diagnóstico. Biologia molecular é área de conhecimento recente com grandes questionamentos a serem respondidos e a atualidade dos fatos científicos mostra que o caminho deverá ser através da identificação de marcadores tumorais. Os grandes avanços na área da informática aprimoraram a análise da imagem celular através da citofotometria de imagem que possibilita através da imunoistoquímica estudar a proliferação celular e a angiogênese que participa em diversos processos tumorais, sendo pesquisadas por vários marcadores. Atualmente estudos são realizados para demonstrar o valor prognóstico de suas expressões, contudo, no adenocarcinoma gástrico resultados têm sido divergentes e estudos escassos. OBJETIVOS: Identificar e quantificar citofotometricamente a expressão dos marcadores da angiogênese através do fator VIII no adenocarcinoma e comparar suas expressões com fa classificação de Bormann, profundidade de invasão tumoral, grau de diferenciação, envolvimento nodal, padrão histológico e idade. MÉTODOS: Foram estudados 21 pacientes com adenocarcinoma gástrico, identificados de 1998 a 2006. Para a detecção do Fator VIII foi realizada imunoistoquímica, com anticorpo policlonal para Fator VIII. Foi realizada análise citofotométrica informatizada pelo sistema SAMBA 4000. RESULTADOS: Dos 21 pacientes 61,90% eram do sexo masculino e 38,10% do feminino, com idade mediana de 65 anos e apenas um não marcou para o Fator VIII (95,24% de marcação. As médias dos índices de marcagem para o Fator VIII foram de 61,14% (desvio-padrão de 15,06, variando de 29,16 a 73,91. Tumores com classifica

  1. Uso da capilaroscopia ungueal como método diagnóstico e prognóstico de rosácea Nailfold capillaroscopy as a diagnostic and prognostic method in rosacea

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    Gabriela Poglia Fonseca

    2011-02-01

    Full Text Available FUNDAMENTOS: Não há um método adequado e fidedigno de avaliação e seguimento da severidade na rosácea. OBJETIVO: Determinar a importância da capilaroscopia periungueal como método diagnóstico e prognóstico em pacientes portadores de rosácea. MÉTODOS: Estudo transversal onde foram submetidos ao exame da capilaroscopia periungueal 8 pacientes com rosácea e 8 controles no período entre maio e julho de 2009. Foram coletados dados clínicos relacionados ao sexo, idade, fototipo, classificação da rosácea de acordo com a classificação de Plewig e Kligman e a classificação da National Rosacea Society. Adicionalmente, avaliamos o tempo de evolução da doença e tratamentos previamente utilizados. RESULTADOS: A grande maioria das pacientes avaliadas (6 das 8 pacientes apresentavam rosácea grau I (vascular ou eritêmato-teleangiectásica. A idade média de duração da rosácea foi de 5,96 anos, sendo que 87,5% faziam tratamento com metronidazol tópico. Nenhum paciente tanto do grupo rosácea como controle demonstrou evidência de desvascularização ao exame capilaroscópico. CONCLUSÃO: A capilaroscopia periungueal apresenta um padrão inespecífico e não parece auxiliar no diagnóstico ou prognóstico da rosácea.BACKGROUND: There is no appropriate and reliable method of evaluating and monitoring severity in rosacea. OBJECTIVE: To determine the importance of nailfold capillaroscopy as a diagnostic and prognostic method for patients with rosacea. METHODS: A cross-sectional study where eight patients with rosacea and 8 control subjects were submitted to nailfold capillaroscopy from May to July 2009. We collected clinical data related to gender, age, skin phototype, and rosacea stage according to Plewig and Kligman classification and the classification of the National Rosacea Society. Additionally, we evaluated the progression of the disease and treatment therapies previously used. RESULTS: The majority of the patients evaluated (6

  2. Características clínicas e prognóstico em pacientes com asma quase fatal em Salvador, Bahia Clinical characteristics and prognosis in near-fatal asthma patients in Salvador, Brazil

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    Eduardo Vieira Ponte

    2011-08-01

    Full Text Available OBJETIVO: Determinar a frequência de asma quase fatal em um grupo de pacientes com asma grave, assim como as características clínicas e o prognóstico desses pacientes em um ano de seguimento. MÉTODOS: Estudo prospectivo envolvendo 731 pacientes de baixa renda com asma grave tratados em um ambulatório de referência para asma na cidade de Salvador (BA. Os pacientes realizaram espirometria na admissão do estudo, receberam medicações para asma e foram monitorizados quanto à frequência de exacerbações durante o seguimento. Uma subamostra de 511 pacientes também respondeu questionários de sintomas e de qualidade de vida relacionada a asma. RESULTADOS: Dos 731 pacientes estudados, 563 (77% eram do sexo feminino, com mediana de idade de 47 anos, e 12% não eram alfabetizados. A maioria dos pacientes apresentava rinite, e 70 (10% relataram asma quase fatal antes da admissão. Desses 70 pacientes, 41 (59% relataram terem sido intubados previamente. Os pacientes com asma quase fatal na admissão eram mais propensos a exacerbações de asma durante o acompanhamento e tiveram menor resposta ao tratamento do que aqueles sem asma quase fatal. Os resultados dos questionários no final do acompanhamento foram semelhantes nos dois grupos de pacientes. CONCLUSÕES: A frequência de asma quase fatal foi alta nesta população de pacientes com asma grave e de baixa renda. Os pacientes com histórico de asma quase fatal tiveram um pior prognóstico que aqueles sem esse histórico, embora tenham recebido o mesmo tratamento. Curiosamente, a intensidade dos sintomas e a qualidade de vida no final do estudo foram semelhantes entre os dois grupos de pacientes.OBJECTIVE: To determine the frequency of near-fatal asthma in a group of severe asthma patients, as well as the clinical characteristics and prognosis of these patients within a one-year follow-up period. METHODS: A prospective study involving 731 low-income patients with severe asthma treated at a

  3. Peritonite bacteriana espontânea na cirrose hepática: prevalência, fatores preditivos e prognóstico Spontaneous bacterial peritonitis in hepatic cirrhosis: prevalence, predictive factors and prognosis

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    F.A.F. Figueiredo

    1999-04-01

    Full Text Available OBJETIVO: Investigar prevalência, fatores preditivos e prognóstico dos episódios de Peritonite Bacteriana Espontânea (PBE na cirrose hepática. METODOLOGIA: Estudamos, prospectivamente, 143 pacientes com cirrose hepática, ambulatoriais ou internados, que foram atendidos nos Serviços de Clínica Médica do HUCFF e de Gastroenterologia do HUPE no período de janeiro/95 a janeiro/96. Estes pacientes foram submetidos a questionário, exame físico, colheita de sangue e paracentese abdominal com colheita de líquido ascítico (LA e, então, acompanhados por um período médio de 4 meses, onde a taxa de mortalidade foi determinada. RESULTADOS: A prevalência de PBE foi cerca de 20%, sendo 24% PBE cultura positiva, 66% Ascite Neutrofílica cultura negativa e 10% Bacterioascite. Na análise univariada, alcançaram significância estatística (p=0.05 como fatores preditivos do episódio de PBE: HGI na semana anterior; passado de encefalopatia hepática; classificação de Child; dosagens séricas de proteínas, albumina, C3, C4 e uréia; dosagens no LA de C3 e C4. Após serem introduzidas na análise multivariada, apenas HGI na semana anterior, albumina sérica e C4 do LA foram independentemente correlacionadas ao episódio de PBE (p=0.05. A mortalidade hospitalar e durante o acompanhento foi de 33,3% e 53,8% para o grupo com PBE; 8,5% e 31,9% para o grupo sem PBE; respectivamente (p=0.01 e p=0.04. A probabilidade cumulativa de sobrevida foi significativamente menor no grupo com PBE. CONCLUSÕES: A PBE é uma complicação freqüente, depende, principalmente, da gravidade da doença hepática e é um marcador de prognóstico desfavorável nos pacientes com cirrose hepática.BACKGROUND: Spontaneous Bacterial Peritonitis (SBP is a common and potentially fatal complication of cirrhosis. Multiple variants of this infection have been described during the past decade. Few studies have investigated SBP in Brazil. MATERIAL AND METHOD: In order to

  4. Valor prognóstico da citologia positiva no lavado peritoneal de pacientes com câncer gástrico ressecável Prognostic role of positive peritoneal cytology in patients with resectable gastric cancer

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    Alexandre Menezes Brito

    2013-04-01

    Full Text Available OBJETIVO: Avaliar o valor prognóstico do lavado peritoneal positivo em pacientes com câncer gástrico sem sinais de disseminação peritoneal ou hematogênica. MÉTODOS: Foram avaliados os pacientes com adenocarcinoma gástrico tratados com operação de intenção curativa. O lavado peritoneal foi classificado como positivo ou negativo para células neoplásicas. Foram obtidos dados demográficos, performance status, histológicos e tipo de operação realizada. Os resultados foram estatisticamente comparados e considerados significantes para valores de pOBJECTIVE: To evaluate the prognostic value of positive peritoneal lavage in patients with gastric cancer without signs of peritoneal or hematogenous spread. METHODS: We evaluated patients with gastric adenocarcinoma treated with curative intent operation. The peritoneal lavage was classified as positive or negative for neoplastic cells. We obtained demographics, performance status, histology and type of surgery. The results were statistically compared and were considered significant for values of p <0.05. RESULTS: We included 72 patients with gastric adenocarcinoma. During a mean follow up of 26 months (one to 39 months we observed 20 local or distant recurrences and 21 deaths. Only the presence of lymph node metastases and the need for resection of adjacent organs were associated with a significant reduction in relapse-free survival. There was a significant reduction in overall survival in patients with angio-lymphatic invasion, lymph node metastasis, requiring resection of multiple organs, need for total gastrectomy and greater invasion of the gastric wall. The presence of tumor cells in the peritoneal cavity was associated with worse overall survival, but without statistical significance. CONCLUSION: There was no statistically significant associations between positive peritoneal citology and recurrence-free survival or overall survival among patients with resectable gastric cancer.

  5. Proporção de linfonodos metastáticos como variável independente de prognóstico no câncer colorretal Metastatic lymph node ratio as an independent prognostic variable in colorectal cancer

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    Denise Gonçalves Priolli

    2008-12-01

    Full Text Available No câncer colorretal, o comprometimento linfonodal é um dos fatores prognósticos mais importantes. Objetivo: Determinar o valor prognóstico independentemente da relação entre linfonodos comprometidos e examinados em doentes com câncer colorretal. MÉTODO: Foram estudados 113 doentes (62 mulheres portadores de câncer do cólon e reto superior. Quinze pertenciam ao estádio I da classificação TNM, 44 ao estádio II, 42 ao estádio III e 24 ao estádio IV. O índice de linfonodos comprometidos foi determinado pela relação entre número total de linfonodos comprometidos e examinados. Os doentes foram divididos segundo a proporção de linfonodos comprometidos em três grupos: ILC-0: sem comprometimento linfonodal; ILC-1: com comprometimento de até 20% dos linfonodos examinados; e ILC-2: com comprometimento neoplásico em 21% ou mais dos linfonodos examinados. As relações entre proporção de linfonodos comprometidos, número de linfonodos ressecados e número de linfonodos comprometidos foram determinadas. Excluíram-se doentes menores de 18 anos, submetidos à neoadjuvância e aqueles onde foram ressecados menos de 12 linfonodos. As variáveis anátomo-clínicas foram analisadas por estatística descritiva. A correlação entre as variáveis foi avaliada pelo teste de Spearman. A sobrevida foi determinada pelos testes de Kaplan-Meier, Log-rank e a análise multivariada pelo modelo de Cox estabelecendo nível de significância de 5%. RESULTADOS: Houve diferença significante na sobrevida de cinco anos em doentes classificados nos diferentes grupos de ILC (p=0,009. Houve relação entre o número total de linfonodos comprometidos e o ILC (p=0,00001, com rs=0,977. Doentes do grupo ILC-0 apresentaram sobrevida global em cinco anos maior que 80%, enquanto os pertencentes aos grupos ILC-1 e ILC-2 a sobrevida global foi menor que 60% e 40%, respectivamente. O comprometimento linfonodal isolado apresentava-se relacionado à sobrevida em

  6. Validade de um índice prognóstico para ocorrência de complicações pulmonares no pós-operatório de cirurgia abdominal alta

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    FILARDO FLÁVIA DE ALMEIDA

    2002-01-01

    Full Text Available OBJETIVO: Observar se a freqüência de complicações pulmonares observadas no pós-operatório de cirurgia abdominal alta eletiva corresponde a freqüência estimada pelo índice prognóstico de Pereira et al Detectar fatores de risco implicados na mortalidade pós-operatória. MÉTODOS: 283 pacientes foram avaliados no pré-operatório por questionário clínico, exame físico, radiograma de tórax e espirometria. Ao final, calculou-se para cada paciente o risco de desenvolver complicações pulmonares pós-operatórias (CPP segundo o índice prognóstico de Pereira et al. No período pós-operatório, registrou-se a ocorrência de complicações, a incidência e causa de óbitos bem como o tipo de cirurgia, a duração da mesma, o tempo de internação total e em unidade de terapia intensiva. RESULTADOS: 69 pacientes (24,4% desenvolveram 87 CPP. Pneumonia foi a mais freqüente (30/87;34%, seguido por atelectasia (21/87;24%, broncoespasmo (15/87;17%, insuficiência respiratória aguda (11/87;13%, ventilação mecânica prolongada (8/87;9% e infecção brônquica (2/87;2%. A análise univariada, seguida pela regressão logística, identificou como fatores de risco independentes para a ocorrência de CPP idade > 56 anos (p=0,0039, tempo cirúrgico > 210 minutos (p=0,0044 e pneumopatia crônica (p=0,0257. Ao comparar a freqüência de CPP que ocorreu em cada uma das oito categorias de risco com a freqüência estimada, não houve diferença estatisticamente significante entre nenhum dos grupos, quando utilizou-se como referência a idade do paciente, o tempo de cirurgia e a presença de pneumopatia crônica. Quando para o cálculo do risco utilizou-se a relação VEF1/CVF, houve diferença entre a freqüência estimada para ocorrência de CPP e a observada, para os pacientes pertencentes ao grupo com VEF1/CVF 210 minutos e ausência de doença clínica. Constatou-se também, por análise univariada, que a presença de doença clínica associada

  7. O Cyfra 21-1 é um determinante prognóstico no carcinoma pulmonar não de pequenas células (CPNPC: resultado de uma meta-análise que incluiu 2063 doentes

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    J.-L. Pujol

    2004-11-01

    Full Text Available RESUMO: O objectivo da presente meta-análise foi determinar o valor prognóstico de níveis séricos pré-terapêuticos elevados de Cyfra 21-1, ajustados a co-variáveis clássicas no CPNPC.Baseou-se em elementos registados em bases de dados de estudos controlados (período de 1993 a 2001, publicados e não publicados, apresentados na forma de abstracts ou incluídos em palestras, conferências ou outras apresentações, que tinham como principal end point a determinação do valor prognóstico dos níveis séricos pré-terapêuticos elevados de Cyfra 21-1, cotejados com outras variáveis prognósticas no CPNPC (estádio TNM, PS, e outras e em que se teve, também, em atenção o tipo de tratamento instituído (cirurgia versus não cirurgia.Foram seleccionadas nove instituições que seguiram 2063 doentes com CPNPC por um período compreendido entre 27 e 78 meses.A sobrevida foi definida como o tempo decorrido entre a data da determinação do valor sérico pré-terapêutico de Cyfra 21-1 até à data da morte do doente. Considerou-se como valor cut-off do mar cador os 3,6 ng/ml; os doentes foram divididos em dois grupos etários, acima e abaixo da mediana de idades, isto é, dos 63 anos.Os elementos colhidos foram analisados estatisticamente utilizando-se o método de Kaplan-Meir para a determinação da distribuição das sobrevidas, enquanto na análise univariada teve-se em conta o teste log-rank e no estudo da regressão multivariada o modelo de Cox.Na série apresentada predominou o sexo masculino (84%, estando 51% dos doentes com um PS de 0-1; 70% dos doentes estavam incluídos no estádio IIIB (27% ou IV (43%; 50% eram carcinomas epidermóides, só 21% foram submetidos a terapêutica cirúrgica e 49% revelaram valores pré-terapêuticos de Cyfra 21-1 acima de 3,6 ng/ml.Pela análise univariada das sobrevidas

  8. O papel da neutropenia no prognóstico do doente oncológico com pneumonia adquirida na comunidade The role of neutropenia on outcomes of cancer patients with community-acquired pneumonia

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    Fátima Caeiro

    2009-08-01

    população geral. No entanto, o papel da neutropenia no prognóstico de doentes neoplásicos hospitalizados com PAC não tinha, ainda, sido investigado. O objectivo do presente estudo foi comparar o prognóstico de doentes neoplásicos e doentes imunocompetentes com PAC, bem como o prognóstico de indivíduos com patologia maligna e neutropenia absoluta ou funcional e sem neutropenia. Foi efectuada uma análise retrospectiva envolvendo 43 hospitais em 12 países no período compreendido entre Junho de 2001 e Janeiro de 2006. Foram incluídos os indivíduos com idade ≥ 18 anos com critérios de PAC, tendo sido eliminados os portadores de infecção VIH. A PAC foi definida pela presença de infiltrado pulmonar “de novo” na radiografia do tórax na altura do internamento, associado a, pelo menos, um dos seguintes parâmetros: tosse ou aumento da intensidade desta; tax 37,8ºC; número de leucócitos no sangue periférico (leucocitose, desvio esquerdo ou leucopenia. Neoplasia foi definida como qualquer tipo de malignidade diagnosticada nos 12 meses anteriores ou neoplasia activa. Considerou-se que esta estaria presente em doentes sob quimioterapia e/ou radioterapia nos 12 meses precedentes ou com sinais ou sintomas de neoplasia ao longo do último ano. Doentes com neoplasia de células escamosas ou basais da pele foram consideradas imunocompetentes. A neutropenia foi classificada como funcional ou absoluta. A primeira estava presente em doentes com doença hematológica maligna. A neutropenia absoluta correspondeu a um número de neutrófilos <500cel/mm³ na admissão hospitalar. Os doentes com PAC foram divididos em dois grupos: doentes não oncológicos – Grupo I, e doentes com neoplasia – Grupo II. Este último foi, por seu turno, subdividido em dois subgrupos, de acordo com o tipo de neoplasia e o número de neutrófilos – doentes com tumor sólido sem neutropenia (Grupo IIa e doentes com neutropenia (Grupo IIb. Foram avaliados a mortalidade, a duração do

  9. Marcadores moleculares no câncer de pulmão: papel prognóstico e sua relação com o tabagismo Molecular markers in lung cancer: prognostic role and relationship to smoking

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    Ricardo Luiz de Menezes Duarte

    2006-02-01

    Full Text Available Estudos epidemiológicos têm demonstrado um nexo causal entre tabagismo e carcinoma de pulmão. Embora a maioria dos cânceres de pulmão esteja associada com tabagismo, somente uma minoria de grandes tabagistas desenvolve essa malignidade, o que leva ao conceito de que fatores genéticos afetam a susceptibilidade individual. As principais alterações moleculares no câncer de pulmão são: genes de supressão tumoral, proto-oncogenes e fatores de crescimento, atividade da telomerase e status de metilação de promotores. Fatores estimuladores da angiogênese (fator de crescimento endotelial vascular e fatores relacionados à proliferação e apoptose de células tumorais (receptor para fator de crescimento epidérmico, p53, K-ras, retinoblastoma, BCL-2 são bem conhecidos. Vários desses fatores genéticos foram investigados, porém nenhum deles apresentou seletividade no que diz respeito à importância prognóstica ou eficácia terapêutica. Estratégias terapêuticas para o tratamento do câncer de pulmão devem considerar essas alterações genéticas precoces para promover o seu reparo ou eliminar as células tumorais.Epidemiological studies have demonstrated a causal relationship between smoking and lung cancer. Although most lung cancer cases are linked to smoking, only a minority of heavy smokers develop lung cancer, leading to the notion that genetic factors affect individual susceptibility. The principal molecular changes in lung cancer are seen in tumor suppressor genes, proto-oncogenes, growth factors, telomerase activity, and methylation status of promoters. Well-known agents include angiogenesis-stimulating factors (such as vascular endothelial growth factor, as well as factors related to tumor cell proliferation and apoptosis (epidermal growth factor receptor, p53, K-ras, retinoblastoma and BCL-2. Several of these genetic factors have already been investigated, but no single parameter has yet presented sufficient selectivity

  10. Significado prognóstico do linfonodo metastático N3 em carcinomas epidermóides de cabeça e pescoço

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    Ali Amar

    Full Text Available OBJETIVO: Avaliar os resultados do tratamento da doença metastática em estádio avançado (N3 e sua relação com o prognóstico do carcinoma espinocelular de cabeça e pescoço. MÉTODO: Foram revisados as informações de prontuários de 241 pacientes, com carcinoma espinocelular de boca, orofaringe, laringe e hipofaringe com metástases cervicais maiores que 6 cm (N3 submetidos à cirurgia e/ou radioterapia, no Departamento de Cirurgia de Cabeça e Pescoço e Otorrinolaringologia do Hospital Heliópolis, Hosphel, São Paulo, de 1988 a 1998. Nos pacientes submetidos à cirurgia foi avaliada a radicalidade cirúrgica, macroscopicamente completa ou não, e naqueles tratados pela radioterapia, foi analisada a resposta do sítio primário e do pescoço imediatamente ao término do tratamento. A sobrevida livre de doença foi estimada pelo método de Kapplan Meier no grupo submetido à cirurgia. RESULTADOS: A irressecabilidade da lesão primária e metastática no pescoço justificou a indicação da radioterapia na dose média de 65 Gy, em 69 pacientes ocorrendo resposta completa no sítio primário em 24(36%, no pescoço em 12 (18%, e em ambos os sítios em 11 casos (16%. No grupo sumetido à cirurgia seguido de radioterapia, a dose média foi de 56 Gy. Dos 25 pacientes com ressecção macroscópica radical do pescoço, cinco (20% recidivaram, e dos cinco com ressecção incompleta e radioterapia, dois tiveram sobrevida de sete a 12 meses após o tratamento, quando foram perdidos de seguimento. A sobrevida livre de doença em dois anos neste grupo foi de 58%. CONCLUSÕES: Para pacientes com linfonodo metastático N3, o esvaziamento cervical seguido de radioterapia foi eficiente no controle regional da doença enquanto que nos inoperáveis, a radioterapia é um tratamento paliativo.

  11. Valor prognóstico da fibronectina plasmática e da classificação de Child-Pugh na cirrose hepática alcoólica: estudo comparativo

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    Parise Edison Roberto

    2004-01-01

    Full Text Available OBJETIVOS: Avaliar o valor prognóstico da fibronectina plasmática (FN, comparativamente à classificação numérica de Child-Pugh e os parâmetros bioquímicos que a compõem, no acompanhamento prospectivo de portadores de cirrose alcoólica durante 18 meses. MÉTODOS: Incluídos 50 pacientes com cirrose alcoólica, diagnosticada por biópsia ou critérios clínico-bioquímicos, excluídos aqueles com hepatocarcinoma ou hemorragia digestiva, infecção ou ingestão alcoólica continuada nos últimos 30 dias. A idade média do grupo foi 51,3±12,6 anos, 72% deles do sexo masculino e classificados 17 como Child-Pugh A, 18 como B e 15 como C. Os valores das bilirrubinas foram dosados pelo método automatizado, eletroforese de proteínas em acetato de celulose e o tempo de protrombina pelo método de Quick. A FN plasmática foi dosada por imunodifusão radial, com anticorpos contra FN humana em géis de agarose a 1%. RESULTADOS: Um paciente foi excluído por óbito de causa não natural e 12 foram a óbito por doença hepática. Os melhores preditores de óbito foram a pontuação de Child-Pugh [escore>10, risco relativo (RR de 11,33 e os valores de bilirrubina (>2,5mg/dL, RR=9,47. A concentração de FN foi significantemente maior nos sobreviventes que naqueles que foram a óbito (185±66 mg/L x 131±38mg/L, p 165mg/L foram melhores indicadores de sobrevida que a classificação de Child-Pugh e seus parâmetros bioquímicos isolados.

  12. Prognostic factors for recurrence of a first seizure during childhood Estudo dos fatores prognósticos na recorrência da primeira crise convulsiva na infância

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    Maria Isabel Bragatti Winckler

    1997-01-01

    Full Text Available This study was designed with the objective of evaluating the chance of recurrence in our area and to answer questions regarding prognostic factors capable of helping in the management of the first seizure in childhood. One hundred and thirty six children from 1 month to 12 years of age seen at the Pediatric Emergency Division of Hospital de Clínicas de Porto Alegre because of a first seizure with or without triggering factors were included in the study. The follow-up included 121 children. We concluded that family history of seizures, presence of triggering factors at first event, seizure type, seizure duration and paroxysmal electroencephalographic abnormalities were predictive factors for seizure recurrence. The recurrence in this sample was 36.36% during the study. Cumulative recurrence risks were 14.88%, 23.14%, 28.93%, 33.06% and 35.54% to 3, 6, 9, 12 and 15 months, respectively.Este estudo foi elaborado com a finalidade de avaliar a possibilidade de recorrência e de responder a questões referentes a fatores prognósticos capazes de auxiliar no manejo da primeira crise convulsiva na infância. Foram incluídas 136 crianças com idades entre 1 mês e 12 anos atendidas no Setor de Emergência Pediátrica do Hospital de Clínicas de Porto Alegre por ocasião da primeira crise convulsiva, com ou sem fator desencadeante. Foram seguidas 121 crianças por 24 meses, concluindo-se que história familiar de crise convulsiva, existência de fatores desencadeantes na primeira convulsão, tipo de crise, duração da crise e alterações paroxísticas no primeiro eletrencefalograma foram fatores preditivos para a recorrência de crise convulsiva. A recorrência foi de 36,36% no tempo em que durou o estudo. Os riscos acumulados para recorrência nesta amostra foram 14,88%, 23,14%, 28,93%, 33,06% e 35,54% para 3, 6, 9, 12 e 15 meses, respectivamente.

  13. Morphofunctional malignancy grading is a valuable prognostic factor for colorectal cancer Graduação morfofuncional de malignidade como valioso fator prognóstico para o câncer colorretal

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    Denise Gonçalves Priolli

    2010-09-01

    Full Text Available CONTEXT: Novel strategies are needed to identify more efficient biomarkers to accurately diagnose prognose and improve the treatment outcome of colorectal cancer. OBJECTIVES: To analyze the functional and morphological features of colorectal cancer to identify the neoplastic patterns that affect patient survival. METHODS: Forty-five patients with colorectal cancer were followed for a minimum of 3 years. Blood levels of carcinoembryonic antigen (CEA were measured by chemiluminescence and immunohistochemical analysis of tissue expression followed by computer-assisted image processing. Tumors were assigned to three morphofunctional classes. The morphofunctional classification was based on combination between histological differentiation and cell polarization. The functional characterization was based on the CEA cell polarization. The tissue polarization of CEA was classified in well-polarized, moderately polarized or nonpolarized cells. Morphofunctional staging was defined by the association between morphofunctional class (polarization and histological differentiation and TNM by score given to each one classification. RESULTS: There was an association between increased CEA tissue expression and loss of histological differentiation (P = 0.01 or loss of polarization capacity (P = 0.03. There was a progressive increase in tissue CEA quantities in accordance with the proposed morphofunctional grading system. Plasma levels of CEA were increased in advanced tumor stages. Blood levels of CEA were increased in advanced morphofunctional stages (P = 0.001. There was a relationship between survival outcome and morphofunctional staging (P = 0.005. CONCLUSION: Morphofunctional staging is a valuable prognostic factor for colorectal cancer and it correlates with plasma CEA levels.CONTEXTO: Novas estratégias são necessárias à identificação de marcadores que promovam precisão no diagnóstico, no prognóstico e melhorem o tratamento de pacientes com c

  14. O impacto do nível da metástase cervical no prognóstico dos pacientes com carcinoma epidermoide de cavidade oral Prognostic impact of the level of neck metastasis in oral cancer patients

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    Hugo Fontan Köhler

    2012-12-01

    Full Text Available Em pacientes com carcinoma epidermoide oral, classifica-se o pescoço pelo número, tamanho e lateralidade das metastáses. OBJETIVO: Avaliar fatores de risco para metástase em nível IV/V e seu impacto no prognóstico do carcinoma epidermoide oral. MÉTODO: Estudo retrospectivo. Critérios de inclusão foram: diagnóstico de CEC, sítio primário em andar inferior da boca sem extensão para sítios extraorais, ausência de tratamento prévio, realização de EC e presença de metástases linfáticas. Por regressão logística, definiram-se fatores de risco e por análise de sobrevivência, fatores prognósticos de recorrência. Análise classificatória realizada por particionamento recursivo. RESULTADOS: Foram incluídos 307 pacientes. Em regressão logística univariada, o estágio pN, embolização vascular, e múltiplos linfonodos comprometidos foram fatores de risco para metástases em nível IV/V. Embolização vascular e múltiplos linfonodos comprometidos permaneceram significativos em análise multivariada. A análise de sobrevivência demonstrou os estágios pT e pN, infiltração perineural, embolização vascular, número de linfonodos metastáticos, razão linfonodal e metástases em níveis IV/V como significativos. Na análise multivariada, PT, pN, embolização vascular linfática e metástases em níveis IV/V permaneceram significativas. Na análise classificatória, o estágio pN não foi significativo quando há metástases em níveis IV/V. CONCLUSÃO: A ocorrência de metástases em níveis IV/V foi significativa para sobrevivência doença-específica.Neck staging in oral cancer depends on the number of compromised nodes, their size and side of occurrence. OBJECTIVE: This paper aims to evaluate risk factors for metastatic nodes in levels IV/V and their prognostic impact on patients with oral carcinoma. METHOD: Retrospective study. Inclusion criteria: pathologist's diagnosis of squamous cell carcinoma, primary tumor in the

  15. Influência da terapêutica hormonal prévia sobre os indicadores de prognóstico do câncer de mama em mulheres na pós-menopausa Influence of previous hormonal therapy on breast cancer prognostic markers in postmenopausal women

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    Eliana Aguiar Petri Nahas

    2005-03-01

    Full Text Available OBJETIVO: avaliar a influência da terapêutica hormonal (TH prévia sobre alguns indicadores de prognóstico do câncer de mama, em pacientes na pós-menopausa. MÉTODOS: estudo transversal por meio da aplicação de questionários e levantamento de prontuários. Foram entrevistadas 157 pacientes com diagnóstico de câncer de mama na pós-menopausa, registrando-se dados clínicos, antecedentes pessoais e familiares, uso de TH e mamografias. Nos prontuários foram obtidas informações sobre o câncer de mama quanto ao diâmetro do tumor, tipo de cirurgia e estudo imuno-histoquímico. Para a estatística empregou-se ANOVA e teste do chi2. RESULTADOS: 38,2% das pacientes eram ex-usuárias de TH e 61,8% não usuárias. O tempo médio de uso da TH foi de 3,7±3,6 anos. As ex-usuárias eram de menor faixa etária e com menor tempo de menopausa quando comparadas às não usuárias (pPURPOSE: to evaluate the influence of previous hormonal therapy (HT on breast cancer prognostic markers in postmenopausal women. Methods: a cross-sectional study was carried out, applying questionnaires and medical record surveys of 157 postmenopausal patients with breast cancer diagnosis. Clinical data, personal and familiar history, HT use, and mammograms were investigated. The medical record surveys yielded information about tumor size, imunohistochemical data, and type of surgery. Statistical analysis was performed using ANOVA and the chi2 test. RESULTS: 38.2% of the patients were HT ex-users and 61.8% were non-users. Mean time of HT use was 3.7±3.6 years. HT ex-users were younger and with a shorter menopause time than non-users (p<0.05. 26.8% of the patients reported previous cases of breast cancer in their families, with no difference between the groups. Of the HT ex-users, 43.3% had previous mammograms, while of the non-users, only 11.3% (p<0.001. Mean tumor size was smaller in HT ex-users (2.3±1.1 cm than in non-users (3.3±1.5cm (p<0.001. The conservative

  16. O papel da neutropenia no prognóstico do doente oncológico com pneumonia adquirida na comunidade** Eur Respir J 2009; 33:142-147

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    S. Aliberti

    2009-07-01

    . Assim, os clínicos podiam sentir-se confiantes e tratar a PAC no doente oncológico não neutropénico como na população geral.No entanto, o papel da neutropenia no prognóstico de doentes neoplásicos hospitalizados com PAC não tinha, ainda, sido investigado O objectivo do presente estudo foi comparar o prognóstico de doentes neoplásicos e doentes imunocompetentes com PAC, bem como o prognóstico de indivíduos com patologia maligna e neutropenia absoluta ou funcional e sem neutropenia.Foi efectuada uma análise retrospectiva envolvendo 43 hospitais em 12 países no período compreendido entre Junho de 2001 e Janeiro de 2006. Foram incluídos os indivíduos com idade≥18 anos com critérios de PAC, tendo sido eliminados os portadores de infecção VIH. A PAC foi definida pela presença de infiltrado pulmonar “de novo” na radiografia do tórax na altura do internamento, associado a, pelo menos, um dos seguintes parâmetros: tosse ou aumento da intensidade desta; tax 37,8 ºC; número de leucócitos no sangue periférico (leucocitose, desvio esquerdo ou leucopenia.Neoplasia foi definida como qualquer tipo de malignidade diagnosticada nos 12 meses anteriores ou neoplasia activa. Considerou-se que esta estaria presente em doentes sob quimioterapia e/ou radioterapia nos 12 meses precedentes ou com sinais ou sintomas de neoplasia ao longo do último ano. Doentes com neoplasia de células escamosas ou basais da pele foram consideradas imunocompetentes.A neutropenia foi classificada como funcional ou absoluta. A primeira estava presente em doentes com doença hematológica maligna. A neutropenia absoluta correspondeu a um número de neutrófilos <500cel/ /mm3 na admissão hospitalar.Os doentes com PAC foram divididos em dois grupos: doentes não oncológicos – Grupo I, e doentes com neoplasia – Grupo II. Este último foi, por seu turno, subdividido em dois subgrupos, de

  17. Is the outcome of schizophrenia really better in developing countries? O prognóstico da esquizofrenia é realmente mais favorável nos países em desenvolvimento?

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    Vikram Patel

    2006-06-01

    Full Text Available That schizophrenia has a better prognosis in non-industrialized societies has become an axiom in international psychiatry; the evidence most often cited comes from three World Health Organization (WHO cross-national studies. Although a host of socio-cultural factors have been considered as contributing to variation in the course of schizophrenia in different settings, we have little evidence from low-income countries that clearly demonstrates the beneficial influence of these variables. In this article, we suggest that the finding of better outcomes in developing countries needs re-examination for five reasons: methodological limitations of the World Health Organization studies; the lack of evidence on the specific socio-cultural factors which apparently contribute to the better outcomes; increasing anecdotal evidence describing the abuse of basic human rights of people with schizophrenia in developing countries; new evidence from cohorts in developing countries depicting a much gloomier picture than originally believed; and, rapid social and economic changes are undermining family care systems for people with schizophrenia in developing countries. We argue that the study of the long-term course of this mental disorder in developing countries is a major research question and believe it is time to thoroughly and systematically explore cross-cultural variation in the course and outcome of schizophrenia.O fato de que a esquizofrenia possui um melhor prognóstico em sociedades não industrializadas tornou-se um axioma na psiquiatria internacional; as evidências mais comumente citadas provêm de três estudos trans-nacionais da Organização Mundial da Saúde (OMS. Ainda que um conjunto de fatores socioculturais tenha sido considerado como contribuinte para o curso da esquizofrenia em diferentes ambientes, possuímos poucas evidências de países de baixa renda que demonstrem claramente a influência benéfica dessas variáveis. Neste artigo

  18. Hemipelvectomias: tratamento, avaliação funcional e prognóstica dos tumores pélvicos Hemipelvectomies: treatment, functional outcome and prognostic of the pelvic tumors

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    Valter Penna

    2011-01-01

    Full Text Available OBJETIVO: Demonstrar a experiência de uma única instituição em hemipelvectomias internas sem reconstrução. Avaliar as cirurgias pélvicas preservadoras e as amputações interílio-abdominais e seu prognóstico. MÉTODOS: 21 pacientes com tumores primitivos pélvicos submetidos à hemipelvectomia com ou sem preservação de membro. Sete foram tratados com hemipelvectomias externas (amputação e 14 com internas, entre junho de 2004 e julho de 2009. A classificação cirúrgica utilizada foi a de Enneking para tumores pélvicos. O método de avaliação funcional foi o escore de ISOLS/MSTS. RESULTADOS: A sobrevida dos pacientes em dois anos foi de 63,9%. A média de sobrevida do grupo todo foi de 43 meses. A avaliação funcional demonstrou que as hemipelvectomias preservadoras com ressecção do osso inominado obtiveram 12,5%, 62,5% e 25% de resultados ruins, bons e excelentes, respectivamente. Nos casos em que o osso inominado foi preservado, os resultados foram 16,7% e 83,3% bons e excelentes, respectivamente. CONCLUSÕES: A hemipelvectomia é procedimento pouco usual e causador de importante limitação funcional e comorbidades. A alternativa de ressecar a hemipelve sem reconstrução tem demonstrado resultados tão bons quanto a não-reconstrução. Os elevados custos médicos, além das possíveis complicações com uso de enxerto e próteses justificam a técnica empregada neste artigo. Nível de Evidência IV, Estudo de caso-controle.OBJECTIVE: To describe the experience of one single institution in internal hemipelvectomies without reconstruction and external hemipelvectomies. METHODS: Twenty-one patients with primary tumors of the pelvic region underwent total hemipelvectomy, at Barretos Cancer Hospital, São Paulo, Brazil, between 2004 and July 2009. Of these, seven were treated with external hemipelvectomy (classic and 14 with internal hemipelvectomy. Evaluation was done based on Enneking's surgical classification for internal

  19. Determinantes morfológicos de prognóstico em pneumonia nosocomial: um estudo em autópsias Morphological prognostic factors in nosocomial pneumonia: an autopsy study

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    Luiz Mário Baptista Martinelli

    2010-02-01

    Full Text Available OBJETIVO: Determinar a prevalência de pneumonia nosocomial nas autópsias em um hospital público universitário; identificar os fatores de risco relacionados à pneumonia nosocomial e os potenciais fatores prognósticos relacionados à ocorrência de pneumonia nosocomial fatal; e correlacionar os achados anatomopatológicos com a ocorrência de pneumonia nosocomial e/ou pneumonia aspirativa. MÉTODOS: Estudo retrospectivo de 199 pacientes autopsiados, maiores de 1 ano de idade, internados no Hospital das Clínicas da Faculdade de Medicina de Botucatu da Universidade Estadual Paulista entre 1999 e 2006, cuja causa de morte (causa básica ou associada foi pneumonia nosocomial. Testou-se a associação dos dados demográficos, clínicos e anatomopatológicos com os desfechos pneumonia nosocomial fatal e pneumonia aspirativa fatal. As variáveis significativas entraram na análise multivariada. RESULTADOS: A idade média foi de 59 ± 19 anos. A prevalência de pneumonia nosocomial em autópsias foi 29%, e essa foi a causa mortis de 22,6% dos pacientes autopsiados. A pneumonia nosocomial fatal correlacionou-se com os achados anatomopatológicos de alterações estruturais tabágicas (OR = 3,23; IC95%: 1,26-2,95; p = 0,02 e acometimento pulmonar bilateral (OR = 3,23; IC95%: 1,26-8,30; p = 0,01. Não houve associações significativas entre as variáveis e pneumonia aspirativa fatal. CONCLUSÕES: Em nossa amostra, a pneumonia nosocomial teve prevalência elevada e foi responsável por quase 25% das mortes. A mortalidade é favorecida por alterações estruturais tabágicas e pneumonia bilateral. Esses achados corroboram os resultados de diversos estudos clínicos sobre pneumonia nosocomial.OBJECTIVE: To determine the prevalence of nosocomial pneumonia in autopsies at a public university hospital; to identify the risk factors for nosocomial pneumonia and the potential prognostic factors associated with fatal nosocomial pneumonia and with fatal

  20. A exenteração pélvica para o câncer de reto: avaliação dos fatores prognósticos de sobrevida em 27 pacientes operados Pelvic exenteration from rectal cancer: evaluation of survival prognostic factors on 27 resectable cases

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    Sergio Renato Pais Costa

    2008-03-01

    Full Text Available OBJETIVO: Identificar os fatores prognósticos de sobrevida dos pacientes submetidos à exenteração pélvica no tratamento curativo do câncer de reto (no Estádio T4 e na recidiva pélvica isolada. MÉTODOS: Os dados completos de 27 pacientes submetidos a esse tipo de operação por adenocarcinoma de reto entre Janeiro de 1996 a Junho de 2006 foram avaliados. Foram estudados diversos fatores prognósticos epidemiológicos, cirúrgicos e histológicos por meio de análise multivariada. RESULTADOS: A mortalidade pós-operatória foi de 7 % (n=2 enquanto a morbidade global foi de 55 % (n=15. A média de sobrevida global foi de 38 meses. A sobrevida global foi maior nos tumores T4 do que nas recidivas pélvicas (47 X 26 meses. Somente o comprometimento linfonodal (N+ foi fator prognóstico negativo na análise multivariada. CONCLUSÃO: A exenteração pélvica para o tratamento do câncer de reto apresenta alta morbidade e considerável mortalidade. Deve ser indicada nos tumores T4, principalmente quando não há disseminação linfonodal.AIM: To identify survival prognostic factors in patients who underwent curative pelvic exenteration from rectal adenocarcinoma (T4 tumors and isolated pelvic recurrence. METHODS: Complete follow-up data were available on 27 patients who underwent this surgical procedure between 1996 and 2006. Multiple prognostic factors were studied by multivariate analysis (epidemiological, surgical and histological. RESULTS: Postoperative mortality was 7 % (n=2 while overall morbidity was 55 % (n=15. Mean of overall survival was 38 months. T4 tumors presented more long-time survival than pelvic recurrence (47 X 26 months. Lymph node disease (N+ was single adverse prognostic factor at multivariate analysis. CONCLUSION: Pelvic exenteration presents both high morbidity and considerable mortality. It should be reserved for T4 tumors, principally when there was no lymph node spreading.

  1. Tipo de terapêutica e fatores de prognóstico na paralisia de Bell: estudo retrospectivo de cinco anos em um hospital português = Therapeutic approach and prognostic factors in Bell´s palsy: retrospective study of five years in a portuguese hospital

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    Ferraria, Lília Andreia Mendes

    2016-01-01

    A presença de otalgia e/ou disgeusia foi o único fator estatisticamente relacionado com a evolução clínica, associando-se a uma menor taxa (51,2% versus 74,4% (p=0,004 e a um maior tempo de recuperação (60,5% versus 79,2% de taxa de recuperação aos três meses (p=0,011. Verificou-se associação estatisticamente significativa do tratamento fisioterápico com maior taxa de recuperação (p=0,049. Em 24,1% (sete de 29 dos doentes com diabetes mellitus houve recorrência da paralisia, contrastando com apenas 6,0% (nove de 51 de recorrência em doentes sem diabetes mellitus (p=0,006. Conclusões: Não houve diferença significativa na taxa de recuperação ou no tempo de recuperação da paralisia de Bell entre os casos que receberam terapêutica com corticosteroide e antiviral ou corticoterapia isolada. O tratamento fisioterápico associou-se à maior taxa de recuperação. Dos fatores de prognóstico estudados, apenas a queixa de otalgia e/ou disgeusia foi significativa, constituindo fator de mau prognóstico na paralisia de Bell. A presença de diabetes mellitus revelou-se fator de risco para recorrência da paralisia

  2. Sarcoma de Ewing: epidemiologia e prognóstico dos pacientes tratados no Instituto de Oncologia Pediátrica, IOP-GRAACC-UNIFESP Ewing's sarcoma: epidemiology and prognosis for patients treated at the Pediatric Oncology Institute, IOP-GRAACC-UNIFESP

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    Davi Gabriel Bellan

    2012-01-01

    Full Text Available OBJETIVO: Traçar o perfil epidemiológico e o prognóstico do sarcoma de Ewing na população brasileira. Material e MÉTODO: Foram avaliados, retrospectivamente, os prontuários de 64 pacientes tratados, com sarcoma de Ewing intraósseo, no Instituto de Oncologia Pediátrica, IOP-GRAACC-Unifesp, no período de 1995 a 2010. RESULTADOS: A análise estatística dos dados obtidos não correlacionou fatores como sexo, trauma, fratura patológica e tempo ao diagnóstico com o desfecho do tratamento. Fatores como metástase inicial, metástase pulmonar, local do tumor, idade, recidiva e tipo de cirurgia indicam resultados que corroboram a literatura consagrada. CONCLUSÃO: O prognóstico no sarcoma de Ewing foi influenciado principalmente pela presença de metástase ao diagnóstico.OBJECTIVE: To outline the epidemiological profile and prognosis for Ewing's sarcoma in the Brazilian population. Material and METHODS: The medical records of 64 patients with intraosseous Ewing's sarcoma who were treated at the Pediatric Oncology Institute, IOP-GRAACC-Unifesp, between 1995 and 2010, were retrospectively evaluated. RESULTS: The statistical analysis on the data obtained did not correlate factors such as sex, trauma, pathological fracture and time taken for case diagnosis with the treatment outcome. Factors such as initial metastasis, lung metastasis, tumor site, age, recurrence and type of surgery showed results corroborating what has been established in the literature. CONCLUSION: The prognosis in cases of Ewing's sarcoma was mainly influenced by the presence of metastases at the time of diagnosis.

  3. Lesão renal aguda em crianças: incidência e fatores prognósticos em pacientes gravemente enfermos Acute kidney injury in children: incidence and prognostic factors in critical ill patients

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    Kenia Machado Souza Freire

    2010-06-01

    Full Text Available OBJETIVOS: Lesão renal aguda caracteriza-se pela redução súbita e, em geral, reversível da função renal com perda da capacidade de manutenção da homeostase do organismo. Em pediatria, as principais causas de lesão renal aguda são sepse, uso de drogas nefrotóxicas e isquemia renal nos pacientes criticamente enfermos. Nesses pacientes, a incidência de lesão renal aguda varia de 20 a 30%, resultando em aumento da taxa de morbi-mortalidade de 40 a 90%. Este estudo tem como objetivo avaliar a incidência de lesão renal aguda nos pacientes internados em unidade de terapia intensiva, classificar a gravidade da lesão renal aguda de acordo com o Pediatric Risk, Injury, Failure, Loss, End-Stage (pRIFLE, analisar a relação entre lesão renal aguda e a gravidade através do Pediatric Index of Mortality (PIM e estudar os fatores prognósticos associados. MÉTODOS: Realizou-se um estudo prospectivo entre julho de 2008 a janeiro de 2009 dos pacientes internados na unidade de terapia intensiva pediátrica do Hospital Infantil Joana de Gusmão - Florianópolis (SC - Brasil. Todos os pacientes foram analisados diariamente através do débito urinário e creatinina sérica e classificados de acordo com pRIFLE. RESULTADOS: No período de acompanhamento foram internadas 235 crianças. A incidência de lesão renal aguda foi de 30,6%, sendo que o pRIFLE máximo durante a internação foi de 12,1% para R, 12,1% para I e 6,4% para F. A taxa de mortalidade foi de 12,3%. Os pacientes que evoluíram com lesão renal aguda apresentaram risco dez vezes maior de óbito em relação aos não expostos. CONCLUSÃO: Lesão renal aguda é uma entidade comum nos pacientes críticos. O diagnóstico precoce a e instituição imediata de medidas terapêuticas adequadas a cada situação clínica podem alterar o curso e a gravidade do envolvimento renal reduzindo a morbi-mortalidade do paciente.OBJECTIVES: Acute kidney injury is characterized by sudden and generally

  4. Correlação da infiltração das células Natural Killer (NK CD 57+ no prognóstico do adenocarcinoma gástrico Gástrico correlation of Natural Killer cell with the prognosis of gastric adenocarcinoma

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    Déborah Rosso

    2012-06-01

    Full Text Available OBJETIVO: Avaliar a concentração da célula Natural Killer (NK no adenocarcinoma gástrico operado, e sua correlação com fatores prognósticos e sobrevida MÉTODOS: Foram estudados 72 doentes portadores de adenocarcinoma gástrico e que foram submetidos à gastrectomia com linfadenectomia D2. A concentração de célula NK foi avaliada por técnica de imunoistoquímica pelo reagente CD57. Os doentes foram divididos em dois grupos: alta concentração de células (n=32 (>15 células /10 campos de grande aumento e baixa concentração (≤ 15 células/10 campos de grande aumento. Esses dois grupos foram comparados com seguintes fatores prognósticos: gênero, idade, localização do tumor, grau de diferenciação celular, classificação de Lauren, estádio, disseminação linfática, metástases e sobrevida. A curva de Kaplan-Meier foi empregada para avaliação de sobrevida e a análise multivariada para avaliação dos fatores prognósticos. RESULTADOS: Não houve relação das células NK com as diversas variáveis estudadas, a não ser com o estádio, onde houve significância (pAIM: To evaluate the concentration of Natural Killer cells (NK cells in adenocarcinoma of the stomach, and its correlation with prognostic factors and survival. METHODS: Seventy-two patients with gastric adenocarcinoma who underwent gastric resection surgery and D2 lymphadenectomy in the period 1997-2007 were analyzed. The concentration of NK cells was evaluated by immunohistochemistry technique with the reagent CD57. Patients were divided into two groups: high concentration (n = 32 (more than 15 cells per 10 high power field and low concentration (less or equal than 15 cells per 10 high power field. These two groups were compared with several prognostic factors such as: gender, age, tumor location, tumor differentiation, Lauren classification, stage, lymph nodes involvement, distant metastases and survival. The Kaplan-Meier curve was applied to evaluate survival

  5. Risk and prognostic factors for diarrheal disease in Brazilian infants: a special case-control design application Fatores de risco e prognósticos para diarréia entre crianças brasileiras: uma aplicação especial do delineamento de casos e controles

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    Sandra Costa Fuchs

    2002-06-01

    Full Text Available The aim of this study was to examine the effect of demographic, socioeconomic, environmental, maternal reproductive, dietary, and nutritional variables on diarrhea risk and prognosis using a hierarchical framework. A case-control study of children aged 0-23 months in Greater Metropolitan Porto Alegre was conducted during the peak season for diarrhea in 1987-1988. Three groups were investigated, with 192 children each. The first group included hospitalized children with an episode of acute diarrhea complicated by moderate to severe dehydration. The second group included children with acute mild diarrhea without signs of dehydration who were identified in the same neighborhood as hospitalized cases. The third group consisted of controls without diarrhea. Mothers were interviewed by trained interviewers using a standardized questionnaire. Data analysis included a hierarchical approach to control for confounding, using conditional logistic regression. Comparison of the three groups aimed to identify risk factors for diarrhea complicated by dehydration, prognostic factors for dehydration, and risk factors for mild diarrhea. Low birth weight, stunting, and lack or breastfeeding acted simultaneously as risk and prognostic factors for diarrhea.O objetivo deste estudo foi examinar o efeito de variáveis demográficas, sócio-econômicas, ambientais, reprodutivas maternas, dietéticas e nutricionais sobre o risco e o prognóstico de diarréia usando análise hierarquizada. Um estudo de caso-controle incluindo crianças entre 0-23 meses de idade, residentes na área metropolitana de Porto Alegre, foi realizado durante os meses de verão de 1987-88. Investigaram-se três grupos de 192 crianças, incluindo as hospitalizadas com um episódio agudo de diarréia e desidratação moderada a grave; as crianças com diarréia aguda leve e sem desidratação, identificadas na vizinhança dos casos, assim como crianças sem diarréia. Entrevistas padronizadas foram

  6. Desempenho de seis modelos de predição prognóstica em pacientes críticos que receberam suporte renal extracorpóreo Performance of six prognostic scores in critically ILL patients receiving renal replacement therapy

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    Elizabeth R. Maccariello

    2008-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Não existe consenso sobre qual modelo prognóstico deva ser utilizado em pacientes com disfunção renal aguda (DRA. O objetivo deste estudo foi avaliar o desempenho de seis escores de prognóstico em pacientes que necessitaram de suporte renal. MÉTODO: Coorte prospectiva de pacientes internados nas unidades de terapia intensiva (UTI de três hospitais terciários que necessitaram de suporte renal por DRA durante 32 meses. Foram excluídos os pacientes crônicos em programa de diálise ou com BACKGROUND AND OBJECTIVES: There is no consensus about prognostic scores for use in patients with acute kidney injury (AKI. The aim of this study was to evaluate the performance of six prognostic scores in predicting hospital mortality in patients with AKI and need for renal replacement therapy (RRT. METHODS: Prospective cohort of patients admitted to the intensive care units (ICU of three tertiary care hospitals that required RRT for AKI over a 32-month period. Patients with end-stage renal disease and those with ICU stay < 24h were excluded. Data from the first 24h of ICU admission were used to calculate SAPS II and APACHE II scores, and data from the first 24h of RRT were used in the calculation of LOD, ODIN, Liaño and Mehta scores. Discrimination was evaluated using the area under ROC curve (AUROC and calibration using the Hosmer-Lemeshow goodness-of-fit test. The hospital mortality was the end-point of interest. RESULTS: 467 patients were evaluated. Hospital mortality rate was 75%. Mean SAPS II and APACHE II scores were 48.5 ±11.2 and 27.4 ± 6.3 points, and median LOD score was 7 (5-8 points. Except for Mehta score (p = 0.001, calibration was appropriate in all models. However, discrimination was uniformly unsatisfactory; AUROC ranged from 0.60 for ODIN to 0.72 for SAPS II and Mehta scores. In addition, except for Mehta, all models tended to underestimate hospital mortality. CONCLUSIONS: Organ dysfunction, general and

  7. Neurological outcome of newborns with neonatal seizures: a cohort study in a tertiary university hospital Prognóstico neurológico de recém nascidos com crises convulsivas: estudo de coorte em hospital terciário

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    Magda Lahorgue Nunes

    2008-06-01

    Full Text Available OBJECTIVE: To describe the neurological outcome of newborns with seizures. METHOD: Cohort study with newborns prospectively followed. Perinatal characteristics and etiological screening were related to outcome in a regression model. RESULTS: During the study 3659 newborns were admitted and 2.7% were diagnosed as having seizures. Hypoxic ischemic encephalopathy (51% was the etiology more frequently associated to seizures and also to postneonatal epilepsy (53%. In the follow up 25 died during the acute neonatal illness and 9 during the first years of life, 19 were diagnosed as having post neonatal epilepsy, 35 had developmental delay and 11 an association among this two comorbidities. A significant association between abnormal postnatal EEG and neuroimaging to developmental delay (p=0.014, p=0.026 was observed. The group of newborns that had seizures presented an increased risk of developing epilepsy compared to newborns from the same cohort without seizures (19.3/100 vs. 1.8/100, pOBJETIVO: Avaliar o prognóstico neurológico de neonatos com crises convulsivas. MÉTODO: Estudo prospectivo, realizado em coorte de neonatos provenientes de hospital terciário. As características clínicas perinatais e os resultados de exames complementares foram correlacionados com prognóstico através de modelo de regressão logística. RESULTADOS: Durante o estudo 3659 neonatos foram internados, sendo que 101 apresentaram crises convulsivas (2,7%. A encefalopatia hipóxico-isquêmica foi a etiologia mais frequentemente associada às crises (51%. O seguimento evidenciou 25 óbitos no período neonatal e 9 durante os primeiros anos de vida, 19 lactentes desenvolveram epilepsia, 35 atraso no desenvolvimento e 11 associação entre os dois desfechos. O modelo de regressão logística aplicado mostrou associação significativa entre EEG pós neonatal anormal e neuroimagem anormal com atraso no desenvolvimento (p=0,014, p=0,026. Os neonatos em estudo, quando

  8. Relação da expressão de fatores de crescimento celular (IGF-1 e (SCF com fatores prognósticos e o alvo da rapamicina em mamíferos (m-TOR em mastocitomas cutâneos caninos

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    Raquel B. Ferioli

    2013-04-01

    Full Text Available O mastocitoma cutâneo (MTC é a neoplasia maligna mais comum na pele dos cães e seu comportamento biológico é muito variável. Dentre os fatores prognósticos estudados nos MTCs, a classificação histopatológica, o índice proliferativo e o padrão de expressão doc-KIT são os que apresentam uma associação mais relevante com o provável prognóstico deste tumor. O objetivo deste trabalho foi avaliar a expressão proteica de fator de crescimento semelhante à insulina tipo 1 (IGF-1, fator de célula tronco (SCF e sua relação com o receptor tirosina quinase (c-KIT, alvo da rapamicina em mamíferos (m-TOR, grau histológico, índice proliferativo pelo KI-67e o número de figuras de mitose (IM com dados clínicos de cães com MTCs . Foram utilizadas 133 amostras de MTCs, provenientes de 133 cães, dispostas em lâminas de microarranjo de tecidos (TMA. A técnica de imuno-histoquímica foi utilizada para a avaliação destas proteínas. Observou-se associação entre SCF e, a graduação histopatológica proposta em 2011, índice mitótico, proliferação celular (KI-67, escore de IGF-1, local da lesão, idade dos animais e padrão imuno-histoquímico do receptor c-KIT. A relação de dependência também foi observada entre IGF-1 e o porte dos animais, IM, m-TOR e c-KIT. A expressão de SCF teve relacção com a agressividade dos MTCs caninos, uma vez que foi mais freqüente em MTCs com c-KIT citoplasmático. A relação entre a expressão de IGF-1, SCF, c-KIT e m-TOR pode estar associada à integralização de suas vias de ação. A expressão de IGF-1 está associada à MTCs em cães de porte grande.

  9. Escore de condição corporal como indicador do prognóstico de gatos com doença renal crônica Body condition score as an indicator of prognosis for cats with chronic renal disease

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    Maria Cristina Nobre e Castro

    2010-02-01

    Full Text Available A caquexia tem sido relacionada à maior mortalidade de pacientes com doença renal crônica, tanto em humanos, como em animais. O escore de condição corporal (ECC pode ser utilizado em conjunto com o peso para melhor avaliação da composição corporal desses animais. O objetivo deste trabalho foi de correlacionar o escore de condição corporal com o prognóstico de felinos com doença renal crônica. Avaliaram-se 110 felinos idosos, dos quais 70 apresentavam-se hígidos (Grupo I e 40 apresentavam doença renal crônica (Grupo II. No grupo I, apenas 5,7% dos gatos apresentaram ECC abaixo do ideal e destes nenhum foi classificado como caquético. No grupo II, 70% dos gatos apresentaram ECC abaixo do ideal, dos quais 32,5% eram caquéticos. A taxa de mortalidade no grupo II foi significantemente maior naqueles caquéticos. O ECC abaixo do considerado ideal indica um prognóstico desfavorável nos pacientes com doença renal crônica.Cachexia has been associated with higher mortality in patients with chronic renal disease both in human and veterinary medicine. Body condition score (BCS can be used along with body weight for a better evaluation of a patient's body composition. The objective of this study was to associate body condition score with prognosis of cats with chronic renal disease. One hundred and ten elderly cats were evaluated; of which 70 were healthy (Group I and 40 had been diagnosed with chronic renal disease (Group II. In Group I, only 5.7% of the cats presented a BCS below ideal, though none were found to be cachectic. In Group II, 70% of the cats presented a BCS below ideal, where 32.5% were cachectic. Mortality was significantly higher within the cachectic patients of Group II. BCS below ideal indicates a poor prognosis for patients with chronic renal disease.

  10. Inform@ed space

    DEFF Research Database (Denmark)

    Bjerrum, Peter; Olsen, Kasper Nefer

    2001-01-01

    Inform@ed space Sensorial Perception And Computer Enchancement - bidrag til Nordisk Arkitekturforskningsforenings IT-konference, AAA april 2001.......Inform@ed space Sensorial Perception And Computer Enchancement - bidrag til Nordisk Arkitekturforskningsforenings IT-konference, AAA april 2001....

  11. Morphometric evaluation of NB84, synaptophysin and AgNOR is useful for the histological diagnosis and prognosis in peripheral neuroblastic tumors (pNTs A avaliação morfométrica de NB84, sinaptofisina e AgNOR é útil para o dignóstico histológico e prognóstico dos tumores neuroblásticos periféricos (pNTs

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    Aparecida de Cássia Carvalho

    2007-01-01

    Full Text Available OBJECTIVE: To study the importance of NB84, synaptophysin and AgNOR and explore the quantitative association of these factors with diagnosis and outcome as well as the association between NB84 and AgNOR and other tumor and stromal factors in twenty-eight peripheral neuroblastic tumors. METHODS: We assessed AgNORs, NB84, synaptophysin and several other markers in tumor tissues from 28 patients with primary neuroblastic tumors. The treatment included: surgery for stage 1, chemotherapy and bone marrow transplantation for most of stages 3 and 4. Histochemistry, immunohistochemistry and morphometry were used to evaluate the amount of tumor staining for AgNOR, NB84 and synaptophysin; the outcome for our study was survival time until death due to recurrent neuroblastic tumors. RESULTS: Only stage (pOBJETIVO: Estudar a importância dos marcadores NB84 e AgNOR e explorar as relações quantitativas entre esses marcadores com o diagnóstico e prognóstico assim como as relações entre NB84 e AgNOR e outros marcadores tumorais e estromais em 28 tumores neuroblásticos periféricos. MÉTODOS: Examinamos AgNOR, NB84 e sinaptofisina e vários outros marcadores em tecidos tumorais de vinte e oito pacientes com tumors neuroblásticos primários. Tratamento dos pacientes incluiu: cirurgia para o estágio 1, quimioterapia e transplante de medula óssea para a maioria dos pacientes nos estágios 3 e 4. Utilizamos histoquímica, imunohistoquímica e morfometria para avaliar a intensidade e extensão de expressão do AgNOR, NB84 e sinaptofisina, tendo o prognóstico dos pacientes incluído o tempo de sobrevida até a morte por recurrência dos tumores neuroblásticos. RESULTADOS: Estadiamento (p<0.01, AgNOR (p<0.01, NB84 (p<0.01 e sinaptofisina (p=0.01 foram marcadores independents de sobrevida. CONCLUSÕES: A determinação dos marcadores NB84 e sinaptofisina mostrou-se como uma ferramenta útil no diagnóstico dos tumors neuroblásticos periféricos; a associa

  12. Immunohistochemical evaluation of e-cadherin, Ki-67 and PCNA in canine mammary neoplasias: correlation of prognostic factors and clinical outcome Avaliação imuno-histoquímica da e-caderina, Ki-67 e PCNA nas neoplasias mamárias caninas: correlação dos fatores prognósticos com a evolução clínica

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    Debora A.P.C. Zuccari

    2008-04-01

    Full Text Available E-cadherin is a cell-cell adhesion molecule and low e-cadherin expression is related to invasiveness and may indicate a bad prognosis in mammary neoplasms. The expression of cell proliferation markers PCNA and especially Ki-67, has also proved to have a strong prognostic value in this tumor class. The expression of these markers was related to the clinical-pathological characteristics of 73 surgically removed mammary tumors in female dogs by immunohistochemistry. There was no statistical correlation between these markers and death by neoplasm, survival time and disease-free interval. However, the loss of e-cadherin expression and marked Ki-67 expression (p=0.016 were considered statistically significant for the diagnosis (p=0.032. When evaluated as independent factors, there was evidence of the relationship between the loss of e-cadherin expression and high PCNA expression with changes in the body status (divided into obese, normal and cachectic of female dogs (p=0.030; there was also evidence of the relationship between pseudopregnancy and e-cadherin alone (p=0.021 and for ulceration and PCNA alone (p=0.035. The significant correlation between the markers expression and these well known prognostic factors used individually or in combination suggests their prognostic value in canine mammary tumors.A e-caderina é uma molécula de adesão celular e a perda de sua expressão esta relacionada à invasão tumoral podendo indicar um prognóstico ruim nas neoplasias mamárias. A expressão dos marcadores de proliferação celular PCNA e especialmente o Ki-67, também têm mostrado forte valor prognóstico nesta classe tumoral. A expressão imuno-histoquímica destes marcadores foi relacionada com as características clinico-patológicas de 73 tumores removidos cirurgicamente de fêmeas caninas. Não houve correlação estatística entre estes marcadores e a morte por neoplasia, tempo de sobrevida e intervalo livre de doença. Entretanto, a perda da

  13. Transtorno desafiador de oposição: uma revisão de correlatos neurobiológicos e ambientais, comorbidades, tratamento e prognóstico Oppositional defiant disorder: a review of neurobiological and environmental correlates, comorbidities, treatment and prognosis

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    Maria Antonia Serra-Pinheiro

    2004-12-01

    Full Text Available Transtorno desafiador de oposição (TDO é uma entidade diagnóstica independente, mas é freqüentemente estudada em conjunto com transtorno de déficit de atenção/hiperatividade (TDAH ou com transtorno de conduta (TC. O objetivo deste artigo é o de fazer uma revisão das evidências existentes, obtidas por meio da base de dados PubMed, sobre achados neurobiológicos no transtorno desafiador de oposição, funcionamento familiar e escolar, comorbidades, prognóstico e opções terapêuticas para transtorno desafiador de oposição. A evidência de correlatos hormonais, genéticos e neurofuncionais de transtorno desafiador de oposição, a conexão com a família, as relações e desempenho escolares, a associação com transtornos do humor, ansiosos e disruptivos, o risco de evolução para transtorno de conduta e de persistência de sintomas de transtorno desafiador de oposição são descritos. Uma revisão do efeito da Terapia Cognitivo-Comportamental e tratamento farmacológico é apresentada. A análise das evidências disponíveis mostra que o impacto de transtorno desafiador de oposição não deve ser ignorado e que o transtorno desafiador de oposição deve ser devidamente abordado. O impacto do tratamento de transtorno desafiador de oposição no prognóstico de longo prazo dos pacientes ainda precisa ser determinado.Oppositional defiant disorder (ODD is an independent diagnostic entity but it is frequently studied in conjunction with Attention-Deficit Hyperactivity Disorder (ADHD or Conduct Disorder (CD. The purpose of this paper is to review the extant evidence, through the PubMed database, on the neurobiological correlates of oppositional defiant disorder and also describe the familiar and school functioning, comorbidities, prognosis and therapeutic options for oppositional defiant disorder. Evidence of hormonal, genetic and neurofunctional findings in oppositional defiant disorder, correlation with the family, school relations

  14. Prognosis of breast cancer during pregnancy: evidence for nursing care El pronóstico de cáncer de mama en el embarazo: evidencias para la atención de enfermería O prognóstico de câncer de mama na gravidez: evidências para o cuidado de enfermagem

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    Ana Fátima Carvalho Fernandes

    2011-12-01

    Full Text Available This integrative review analyzed evidence available in the literature concerning the prognosis of breast cancer during pregnancy. The following databases were used for selecting studies: PubMed, CINAHL and LILACS. A total of 240 primary studies were identified; 13 papers were included in the integrative review’s sample after reading the titles and abstracts and according to the established inclusion and exclusion criteria. There is evidence indicating that pregnancy does not worsen the evolution of breast cancer and a poor prognosis is related to late stage tumors. Among the gaps identified in the studied theme, the need for further studies addressing nursing care provided to pregnant women with breast cancer is highlighted in order to promote improved care in the context of health care.Esta revisión integradora de la literatura objetivó analizar las evidencias disponibles en la literatura sobre el pronóstico del cáncer de mama durante el embarazo. La selección de los estudios primarios fue realizada en las bases de datos PubMed, CINAHL y LILACS; se identificaron 240 estudios primarios. Después de la lectura de los títulos y resúmenes y establecimiento de los criterios de inclusión y exclusión, 13 artículos fueron incluidos en la muestra de la revisión integradora. En la síntesis del conocimiento producido hay evidencias que indican que el embarazo no empeora la evolución del cáncer de mama y el pronóstico malo está relacionado con la estadificación clínica tardía del tumor. Entre las lagunas en el tópico investigado hay que resaltar la necesidad de realizar estudios sobre la atención de enfermería prestada a mujeres embarazadas con cáncer de mama para mejoría del cuidado en el contexto de la atención a la salud.O presente estudo teve como objetivo analisar as evidências disponíveis na literatura sobre o prognóstico de câncer de mama na gravidez. O método de revisão adotado foi a revisão integrativa. Para a

  15. Proteína C-reativa: marcador inflamatório com valor prognóstico em pacientes com insuficiência cardíaca descompensada C-reactive protein: an inflammatory marker with prognostic value in patients with decompensated heart failure

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    Humberto Villacorta

    2007-05-01

    Full Text Available FUNDAMENTO: A inflamação vem sendo implicada na fisiopatologia de uma série de doenças cardiovasculares. A proteína C-reativa (PCR titulada é um marcador de inflamação de fácil obtenção na sala de emergência. OBJETIVO: Estudar o valor prognóstico da PCR em pacientes admitidos por insuficiência cardíaca (IC descompensada. MÉTODOS: Coorte prospectiva de 119 pacientes com IC descompensada, atendidos na sala de emergência, com média de idade de 74 ± 11 anos, dos quais 76 (64% eram do sexo masculino. Todos estavam em classe funcional III ou IV da New York Heart Association. A dosagem da PCR foi realizada por ocasião da admissão na sala de emergência, pelo método de nefelometria. Os pacientes foram acompanhados, após a alta hospitalar, por um tempo médio de 12 ± 9,7 meses e o desfecho analisado foi a mortalidade cardiovascular. RESULTADOS: Houve 44 (36,9% óbitos, todos por causa cardiovascular. Indivíduos com PCR > 3 mg/dl apresentaram maior mortalidade que indivíduos com valores inferiores a esse (p=0,018. A análise multivariada pelo modelo proporcional de Cox destacou como fator independente para prognóstico mais importante a PCR (razão de chances de 0,0916 [intervalo de confiança de 95% = 0,0341 a 0,1490] para aumentos de uma unidade na PCR. CONCLUSÃO: A PCR é um preditor independente de mortalidade cardiovascular em pacientes com IC descompensada, indicando que a inflamação representa componente importante na fisiopatologia da doença.BACKGROUND: Inflammation has been implicated in the pathophysiology of a series of cardiovascular diseases. C-reactive protein (CRP is a marker of inflammation easily obtained in the emergency room. OBJECTIVE: To study the prognostic value of CRP in patients admitted for acute decompensated heart failure (ADHF. METHODS: A prospective cohort of 119 patients with ADHF treated in the emergency room. Mean age was 74±11 years and 76 (64% of patients were male. All were New York Heart

  16. Perfil e prognóstico a longo prazo dos pacientes que recebem terapia insulínica em unidades de terapia intensiva clínico-cirúrgica: estudo de coorte Profile and long-term prognosis of glucose tight control in intensive care unit - patients: a cohort study

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    Márcia Inês Boff

    2009-12-01

    Full Text Available OBJETIVOS: Hiperglicemia induzida por estresse ocorre com freqüência em pacientes criticamente doentes e tem sido associada a aumento de mortalidade e morbidade tanto em pacientes diabéticos, quanto em não diabéticos. O objetivo deste estudo foi avaliar o perfil e prognóstico a longo prazo dos pacientes críticos que recebem terapia insulínica contínua na unidade de terapia intensiva. MÉTODOS: Coorte prospectiva, em que foram estudados os pacientes internados na unidade de terapia intensiva no período de 1 ano. Foram analisadas variáveis demográficas, escores de gravidade e o prognóstico a curto na unidade de terapia intensiva, e a longo prazo (2 anos da alta da unidade de terapia intensiva. Os pacientes foram classificados em 2 grupos: pacientes que receberam terapia insulínica contínua para controle glicêmico indicada pela equipe da unidade de terapia intensiva e pacientes que não receberam terapia insulínica. RESULTADOS: Dos 603 pacientes incluídos no estudo, 102 (16,9% receberam terapia insulínica contínua, objetivando níveis glicêmicos OBJECTIVES: Stress-induced hyperglycemia is frequent in critically ill patients and has been associated with increased mortality and morbidity (both in diabetic and non-diabetic patients. This study objective was to evaluate the profile and long-term prognosis of critically ill patients undergoing tight glucose-control. METHODS: Prospective cohort. All patients admitted to the intensive care unit over 1-year were enrolled. We analyzed demographic data, therapeutic intervention, and short- (during the stay and long-term (2 years after discharge mortality. The patients were categorized in 2 groups: tight glucose control and non-tight glucose-control, based on the unit staff decision. RESULTS: From the 603 enrolled patients, 102 (16.9% underwent tight control (glucose <150 mg/dL while 501 patients (83.1% non-tight control. Patients in the TGC-group were more severely ill than those in the

  17. Carcinoma do colo do útero: taxa de sobrevida e fatores prognósticos em mulheres no Estado de Mato Grosso Carcinoma de cuello de útero: tasa de sobrevida y factores pronósticos en mujeres en el Estado de Mato Grosso Cervical carcinoma: survival rate and prognostic factors in women in the state of Mato Grosso

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    Janete Tomiyoshi Nakagawa

    2011-01-01

    Full Text Available OBJETIVOS: Analisar a taxa de sobrevida de mulheres submetidas ao tratamento de câncer do colo do útero no Estado de Mato Grosso e identificar os fatores prognósticos que mais influenciaram no tempo de sobrevida. MÉTODOS: Estudo tipo coorte, realizado por meio daanálise dos prontuários clínicos, e dados do Sistema de Informação do Colo do Útero, Sistema de Informação sobre Mortalidade, Sistema de Informação Autorização de Procedimentos Alta Complexidade. A população correspondeu a 55 mulheres que apresentaram esse tipo de carcinoma e tiveram seguimento clínico entre 2002 e 2007. RESULTADOS: A taxa de sobrevida global foi de 66,7%. Os fatores prognósticos que influenciaram na taxa de sobrevida foram: idade, presença de sintomatologia sugestiva de câncer cervical e estágio tardio da doença no momento do diagnóstico. CONCLUSÃO: Apesar da taxa de sobrevida global encontrada assemelhar-se às taxas de países desenvolvidos, foi menor em mulheres com condições sociais desfavoráveis.OBJETIVOS: Analizar la tasa de sobrevida de mujeres sometidas al tratamiento de cáncer de cuello de útero en el Estado de Mato Grosso e identificar los factores pronósticos que más influyeron en el tiempo de sobrevida. MÉTODOS: Estudio de tipo cohorte, realizado por medio del análisis de las historias clínicas, entre otros. La población correspondió a 55 mujeres que presentaron ese tipo de carcinoma y tuvieron seguimiento clínico entre 2002 y 2007. RESULTADOS: La tasa de sobrevida global fue del 66,7%. Los fatores pronósticos que influyeron en la tasa de sobrevida fueron: edad, presencia de sintomatología sugestiva de cáncer cervical y estadío tardío de la enfermedad en el momento del diagnóstico. CONCLUSIÓN: A pesar de que la tasa de sobrevida global encontrada se asemeje a las tasas de países desarrollados, fue menor en mujeres con condiciones sociales desfavorables.OBJECTIVES: To analyze the survival rate of women undergoing

  18. Escore para avaliação do estado nutricional: seu valor na estratificação prognóstica de portadores de cardiomiopatia dilatada e insuficiência cardíaca avançada Score for nutritional status evaluation: the role played in the prognostic stratification of dilated cardiomyopathy and advanced heart failure patients

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    Luiz Guilherme Veloso

    2006-08-01

    Full Text Available OBJETIVO: Desenvolver método de avaliação do estado nutricional do paciente através de escore que expresse o estado nutricional de maneira universal e verificar se esse escore seria eficaz na estratificação prognóstica de pacientes com insuficiência cardíaca (IC avançada. MÉTODOS: Para compor o escore foram selecionados métodos de avaliação que procurassem quantificar forma de medida do estado nutricional: a porcentagem ideal do peso, a espessura da prega tricipital, os percentis da circunferência da massa muscular do braço, os níveis séricos de albumina, a contagem global de linfócitos. Para validá-lo, aplicou-se o escore num grupo de 95 pacientes com idade inferior a 65 anos, sem evidências de doenças consumptivas e analisou-se se esse escore manteria correlação com os dados clínicos da IC e permitiria estratificar o prognóstico. RESULTADOS: A situação nutricional esteve alterada nos pacientes e escore elevado sugerindo desnutrição moderada ou intensa foi observado em 31/95 (32,6% dos casos. Não houve correlação entre os valores do escore nutricional, duração dos sintomas e grau de disfunção ventricular. Os pacientes com escore nutricional elevado apresentaram tendência de maior mortalidade (p=0,0606. CONCLUSÕES: Os dados sugerem que a desnutrição atinge cerca de 1/3 dos pacientes com IC avançada. Um escore que englobou cinco parâmetros de avaliação nutricional teve boa correlação com a avaliação clínica e permitiu avaliar globalmente a desnutrição de portadores de IC. Escore superior a 8 identificou pacientes com maior probabilidade de morrer, confirmando que pacientes mais desnutridos têm pior evolução.OBJECTIVE: Develop a method for the evaluation of patient’s nutritional status through a score that expresses universal nutritional status, as well as investigate if that score would be efficient for the prognostic stratification of advanced heart failure (HF pts. METHODS: The score was

  19. Sensibilidade e especificidade da oximetria fetal de pulso e da cardiotocografia durante o parto: comparação entre os métodos no prognóstico de recém-nascidos Acidóticos Sensitivity and specificity of fetal pulse oximetry and cardiotocography during labor: comparison of both methods regarding prognosis of acidotic newborns

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    Edson Nunes de Morais

    1999-07-01

    Full Text Available Objetivo: estudar a sensibilidade e a especificidade dos valores de saturação de oxigênio fetal (SpO2 e padrões da freqüência cardíaca fetal (FCF durante o parto, no prognóstico de fetos acidóticos ao nascimento. Pacientes e Métodos: os valores fetais de SpO2 foram obtidos pela técnica da oximetria de pulso. Um valor de SpO2 > ou = 30% foi considerado normal, e 10 minutos no intervalo entre contrações, foi considerado anormal. A SpO2 fetal e os traçados de FCF foram obtidos continuamente no primeiro e segundo períodos do parto. A classificação utilizada para a FCF foi a do NICHD19. Resultados: um total de 72 casos foram estudados. A sensibilidade e especificidade com base na SpO2 fetal foram respectivamente de 61,5% e 96,6%, ao passo que a sensibilidade e especificidade baseadas nos padrões de FCF foram respectivamente 69,2% e 66,1%. Os valores preditivos positivo e negativo em função da SpO2 fetal foram respectivamente 80% e 91,9%; em função dos padrões de FCF foram respectivamente 31% e 90,7%. Conclusões: uma boa especificidade da SpO2 para o prognóstico de recém-nascidos acidóticos foi encontrada, se comparada com a especificidade dos padrões de FCF, ao passo que a sensibilidade foi relativamente baixa para os dois métodos. Entretanto, o número de fetos acidóticos é muito pequeno para conclusões.Purpose: to study the sensitivity and specificity based on fetal oxygen saturation (SpO2 values and fetal heart rate (FHR patterns during labor, for the prognosis of acidotic fetuses at birth. Patients and Methods: SpO2 values were obtained by fetal pulse oximetry technique. A fetal SpO2 value > or = 30% was considered normal, and an SpO2 which remained <30.0% for more than 10 min between contractions was considered abnormal. Fetal SpO2 and FHR tracings were obtained during the first and second stage of labor. FHR classification used in the study has been derived from the National Institute of Child Health and Human

  20. Avaliação prognóstica individual na UTI: é possível diferenciar insistência terapêutica de obstinação terapêutica? Individual prognostic assessment in the intensive care unit: can therapeutic persistence be distinguished from therapeutic obstinacy?

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    Cristiano Corrêa Batista

    2009-08-01

    Full Text Available OBJETIVOS: A disponibilidade de alta tecnologia na unidade de terapia intensiva tem-se transformado, muitas vezes, em instrumento potencializador de sofrimento ao aumentar o tempo do processo de morrer. Diferenciar insistência terapêutica de obstinação terapêutica tem sido um grande desafio da medicina atual. O objetivo deste estudo foi avaliar a relação benefício versus malefício do uso de terapias que sustentam as funções vitais por meio de um sistema evolutivo de avaliação prognóstica individual. MÉTODOS: Estudo de coorte, prospectivo, observacional, desenvolvido na unidade de tratamento intensivo do Hospital Universitário São Francisco de Paula da UCPel, Pelotas, RS no período de 1° de março de 2006 a 31 de agosto de 2007. Foram registradas: a avaliação prognóstica individual por meio de um sistema evolutivo, utilizando o índice UNICAMP II associado aos níveis séricos de albumina, transferrina e linfócitos; as terapias mantenedoras das funções vitais; o desfecho. A análise estatística foi realizada utilizando o teste t de Student, a ANOVA, o teste do Qui-quadrado, o teste exato de Fisher, o teste de correlação de Spearman e a curva ROC. Foi considerado estatisticamente significativo um valor p OBJECTIVES: Availability of state-of-the-art technology at intensive care units has often turned into a tool aggravating suffering by prolonging the end-of-life process. Distinguishing therapeutic persistence from therapeutic obstinacy has become a great challenge for present-day medicine. The aim of this study was to assess the benefit-harm relation in the use of life-sustaining therapies by means of an evolutionary system of individual prognostic assessment. METHODS: A cohort, prospective, observational study at the intensive care unit of the São Francisco De Paula University Hospital of UCPel, Pelotas RS from March 2006 to August 31, 2007. Individual prognostic assessments were recorded by using an evolutionary

  1. Carcinoma de células escamosas oral - contribuição de vírus oncogênicos e alguns marcadores moleculares no desenvolvimento e prognóstico da lesão: uma revisão Oral squamous cell carcinoma - contribution of oncogenic virus and some molecular markers in the development and prognosis of the lesion: a review

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    Beatriz da Rocha Miranda Venturi

    2004-06-01

    Full Text Available O carcinoma de células escamosas oral é um evento de muitas etapas, cuja incidência cresce continuamente, particularmente em jovens, numa amplitude que não pode ser completamente explicada pelo aumento da exposição a fatores de risco, como o tabaco e o álcool. Recentes investigações moleculares sugerem que existem múltiplos eventos genéticos, e vírus oncogênicos que são capazes de alterar as funções normais de oncogenes e genes de supressão tumoral. O objetivo deste artigo foi revisar o conhecimento atual sobre o papel do papilomavírus humano (HPV, Epstein-Barr vírus (EBV, P53 e telomerase no desenvolvimento e prognóstico do carcinoma de células escamosas oral.Oral squamous cell carcinoma is a multistep event that continues to increase in incidence, particularly in the young, and to an extent that cannot be fully explained by increased exposure to known risk factors, as tobacco or alcohol. Recent molecular investigations suggest that there are multiple genetic events, and oncogenic virus that are able to alter the normal functions of oncogenes and tumor suppressor genes. The aim of the present article was to review the current knowledge on the role of Human papillomavirus (HPV, Epstein-Barr virus (EBV, P53 and telomerase in the development and prognosis of the oral squamous cell carcinoma.

  2. Indicadores de Prognóstico em Câncer de Mama com Axila Negativa: Receptor de Estrógeno e Expressão de P53 e de c-erbB-2 Prognostic Indicators In Lymph Node-Negative Breast Cancer: Estrogen Receptor and P53 and c-erbB-2 Protein Expression

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    Adriana Harter Teixeira Bolaséll

    2000-08-01

    Full Text Available Objetivo: avaliar o valor prognóstico do receptor de estrógeno e da expressão das proteínas p53 e c-erbB-2 no câncer de mama com axila negativa. Métodos: foi realizado estudo imuno-histoquímico em material incluido em parafina, do arquivo do Instituto de Pesquisas Cito-Oncológicas (IPCO da Fundação Faculdade Federal de Ciências Médicas de Porto Alegre (FFFCMPA, de 50 casos de câncer de mama sem comprometimento dos linfonodos axilares, em mulheres menopausadas, tratadas na Irmandade da Santa Casa de Porto Alegre (ISCMPA e no Hospital Santa Rita de Porto Alegre (HSR de janeiro 1990 a dezembro de 1994. Para análise estatística foram utilizados os testes de c² com correção de Yates, teste exato de Fisher e curvas de sobrevida pelo método de Kaplan-Meier comparados pelo teste log rank. O seguimento médio das pacientes foi de 3,6 anos (3,1-4,5. Dos 50 casos, 14 apresentaram recidiva no período observado. Resultados: a média de idade foi 61 anos (variação de 46 a 78 anos. A mastectomia radical modificada (MRM foi realizada em 35 pacientes (70% e 15 (30% foram submetidas a setorectomia com esvaziamento axilar e posterior radioterapia. Metade das pacientes que apresentaram recidiva apresentaram-na nos três primeiros anos após o diagnóstico. O tamanho médio do tumor foi 2,8 cm (1,98-3,13 e o tipo histológico mais freqüente foi o carcinoma ductal infiltrante de tipo histológico não-especial (92%, conforme a graduação histológica de Bloom e Richardson, sendo 3 grau I (6,6%, 35 grau II (76% e 8 grau III (17,4%; nos tumores que recidivaram não houve nenhum grau I, 9 (25,7% eram grau II e 3 (37,5% eram grau III. Em relação ao prognóstico, a taxa de intervalo livre de doença foi menor quando da associação de tumor pouco diferenciado (grau III com receptor de estrógeno negativo (p = 0,006, p53 positivo (p = 0,006 e c-erbB-2 positivo (p = 0,001. Conclusão: mulheres menopausadas com câncer de mama sem comprometimento

  3. Comparação entre a relação PCR/albumina e o índice prognóstico inflamatório nutricional (IPIN Comparison of PCR/albumin ratio with prognostic inflammatory nutritional index (PINI

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    Camila Renata Corrêa

    2002-07-01

    Full Text Available Objetivo: Simplificar o cálculo do índice prognóstico inflamatório nutricional (IPIN empregando número menor de variáveis com conseqüente redução do custo da análise. Materiais e métodos: Foram estudados 54 pacientes e 12 indivíduos-controle com 48 ± 20 (média ± dp anos de idade. As principais patologias dos pacientes eram: doença arterial periférica (22, pênfigo foliáceo (7, doença inflamatória intestinal (7, trauma (6 e pós-operatório de ortognatia (3. Foram obtidas amostras de sangue periférico, colhidas em jejum para dosagens de proteínas positivas (+ e negativas (- de fase aguda (PFA pelo método nefelométrico. Proteína C reativa (PCR, alfa-1-glicoproteína-ácida (alfa-1-GA, alfa-1-antitripsina (alfa-1-AT e ceruloplasmina (CER foram as PFA+ e albumina (Alb, transtiretina (TTR, transferrina (TF e proteína ligadora do retinol (RBP foram as representantes das PFA-. Esses valores foram analisados quanto à associação de correlação isolada ou associadamente na fórmula do índice prognóstico inflamatório e nutricional (IPIN = PCR + alfa-1-GA / Alb + TTR. De acordo com o índice prognóstico inflamatório e nutricional, os pacientes foram classificados em grupo-controle (G1; pacientes sem infecção/inflamação (IPIN 1, G3. Em seguida os pacientes do G3 foram subdivididos em baixo risco (G3A, n = 16; médio risco ( G3B, n = 10; alto risco (G3C, n = 6 e com risco de morte (G3D, n = 11. Os resultados foram correlacionados entre si (teste de Spearman ou submetidos às comparações entre grupos (teste de Kruskall-Wallis. Resultados: Houve relação significativa entre as variáveis PCR ´ alfa-1-GA (r = 0,49, Alb ´ TTR (r = 0,60, Alb ´ RBP (r = 0,58, Alb ´ TF (r = 0,39, TTR ´ RBP (r = 0,56 e TTR´ TF (r = 0,43 e as melhores relações encontradas entre PFA+ e PFA- foram: PCR ´ Alb (r = - 0,71, PCR ´ TTR (r = - 0,54, PCR ´ TF (r = - 0,39 e alfa-1-GA ´ Alb (r = - 0,35. Os valores do IPIN mostraram a

  4. Sobrevida e fatores prognósticos de pacientes com câncer de próstata clinicamente localizado Sobrevida y factores pronósticos de pacientes con cáncer de próstata clínicamente localizado Survival and prognostic factors of patients with clinically localized prostate cancer

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    Arn Migowski

    2010-04-01

    Full Text Available OBJETIVO: Estimar a sobrevida e os fatores prognósticos clínicos (pré-tratamento de pacientes com adenocarcinoma de próstata localizado. MÉTODOS: Coorte hospitalar composta por 258 pacientes do Instituto Nacional de Câncer, Rio de Janeiro, RJ, de 1990 a 1999. As funções de sobrevida em cinco e dez anos foram calculadas empregando-se o estimador de Kaplan-Meier, tomando-se como início da observação a data do diagnóstico histológico e como eventos os óbitos por câncer de próstata. Para avaliação dos fatores prognósticos pré-tratamento foram calculadas hazard ratios (HR e intervalos com 95% de confiança, seguindo-se o modelo de riscos proporcionais de Cox. O pressuposto desses riscos foi avaliado pela análise dos resíduos de Schoenfeld e a influência de valores aberrantes pelos resíduos martingale e escore. RESULTADOS: Dos 258 pacientes estudados, 46 foram a óbito durante o período de seguimento.A sobrevida específica por câncer de próstata foi de 88% em cinco anos e de 71% em dez. A classificação de Gleason maior que 6, PSA maior que 40ng/ml, estádio B2 e cor da pele branca foram marcadores independentes de pior prognóstico. CONCLUSÕES: A classificação de Gleason, o toque retal e o valor do PSA possuem grande poder preditivo e devem ser utilizados na estratificação de risco pré-tratamento dos pacientes com câncer de próstata localizado.OBJETIVO: Estimar la sobrevida y los factores pronósticos clínicos (pre-tratamiento de pacientes con adenocarcinoma de próstata localizado. MÉTODOS: Cohorte hospitalaria compuesta por 258 pacientes del Instituto Nacional de Cáncer, Rio de Janeiro, Sureste de Brasil, de 1990 a 1999. Las funciones de sobrevida en cinco y diez años fueron calculadas empleándose el estimador de Kaplan-Meier, tomándose como inicio de la observación la data del diagnóstico histológico y como eventos los óbitos por cáncer de próstata. Para evaluación de los factores pronósticos pre

  5. Prognostic value of non-reactive burst suppression EEG pattern associated to early neonatal seizures Valor prognóstico do EEG com padrão de surto-supressão não reativo associado a convulsões neonatais precoces

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    Magda Lahorgue Nunes

    2005-03-01

    Full Text Available ABSTRACT Seizures are the most frequent neurological event in newborns and clinical data suggest that etiology is the dominant factor in long term outcome. However, there are consistent background EEG abnormalities associated to neonatal seizures that are usually related to unfavorable outcome as the burst - suppression pattern. OBJECTIVE: The objective of this study was to correlate clinical and EEG features associated to long - term outcome of newborns with non - reactive burst - suppression (BS EEG. METHOD: Newborns included in the study were selected from our database and had conceptional age (at the time of first EEG >37 weeks, EEG recordings with non - reactive BS available for review and clinical follow up. RESULTS: 12 newborns met inclusion criteria, 50% had seizures in the first day of life. Seizures became refractory to treatment in all of them. In 50% the etiology of seizures was considered cryptogenic, 33% had inborn errors of metabolism and 17% had clinical history and neuroimage suggestive of hypoxic-ischemic encephalopathy. The follow-up showed that 7/12 infants deceased, 3 during the first year of life, and one in the neonatal period. All the survivors had severe developmental delay and multifocal neurological impairment. 92% developed refractory epilepsy, 58% were latter diagnosed with West syndrome. CONCLUSION: The non-reactive BS pattern may appear related to many neonatal neurological disorders and is associated with early and refractory neonatal seizures. It is clearly associated with elevated morbidity and mortality and to the development of post-neonatal epilepsy.RESUMO Convulsões representam o evento neurológico mais freqüente no período neonatal e a etiologia das crises parece ser o aspecto clínico mais associado ao prognóstico a longo prazo. Entretanto, existem padrões anormais de EEG, que de forma consistente relacionam-se a prognóstico, entre eles o padrão de surto - supressão. OBJETIVO: Este estudo teve

  6. Ultrassonografia uretrovesical como método eficaz de avaliação dos parâmetros prognósticos de tratamento cirúrgico da incontinência urinária de esforço Urethrovesical ultrasonography as an effective method for evaluating prognostic parameters in the surgical management of stress urinary incontinence

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    Frederico Teixeira Brandt

    2009-06-01

    Full Text Available OBJETIVO: Comparar parâmetros ultrassonográficos relacionados à junção uretrovesical e uretra proximal em pacientes curadas e não curadas, tratadas cirurgicamente pela técnica de Burch, com a finalidade de estabelecer se há correspondência com fatores prognósticos. MATERIAIS E MÉTODOS: Trinta pacientes foram selecionadas e divididas em dois grupos: 15 consideradas clinicamente curadas e 15 consideradas não curadas. As pacientes foram submetidas a ultrassonografia transvulvar no pré-operatório e aos 30 e 180 dias do pós-operatório. RESULTADOS: No pré-operatório, o deslocamento da uretra proximal foi maior nas pacientes curadas (15,87 ± 4,55 mm × 12,47 ± 3,52 mm - p OBJECTIVE: To compare sonographic parameters related to the urethrovesical junction and proximal urethra in cured and not cured patients surgically treated with the Burch technique, for establishing a possible correlation with prognostic factors. MATERIALS AND METHODS: Thirty female patients were selected and divided into two groups: 15 patients considered as clinically cured and 15 not cured. The patients were submitted to preoperative transvulvar ultrasonography, with the examination being repeated at the 30th and 180th postoperative days. RESULTS: At the preoperative examination, the proximal urethra displacement was largest in the cured patients (15.87 ± 4.55 mm × 12.47 ± 3.52 mm - p < 0.05. At the postoperative examination, with strain, the vertical distance of the urethrovesical junction and the proximal urethra were largest in the cured patients (12.87 ± 5.80 mm × 5.13 ± 6.55 mm - p < 0.01; and 13.07 ± 6.44 mm × 6.20 ± 6.14 mm - p < 0.01, and the vertical displacement of the urethrovesical junction and proximal urethra was largest in the not cured patients (8.47 ± 3.98 mm × 5.13 ± 2.36 mm - p < 0.001; and 8.33 ± 4.54 mm × 5.20 ± 2.90 mm - p < 0.05. CONCLUSION: Ultrasonography of the urethrovesical junction and proximal urethra can be

  7. Prognostic significance of occult lymph node micrometastasis in gastric cancer: a histochemical and immunohistochemical study based on 1997 UICC TNM and 1998 JGCA classifications Significância prognóstica das micrometástases ocultas em linfonodos no câncer gástrico: estudo histoquímico e imunoistoquímico baseado nas classificações UICC TNM de 1997 e JCGCA de 1998

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    Nelson Fausto Dell'Aquila Jr

    2008-12-01

    Full Text Available BACKGROUND: Micrometastasis is a single or a cluster of malignant cells inside the lymph node that are not detected by routine histopathological sections. Micrometastasis is related to poorer prognosis in many gastric cancer studies the real significance of these cells is still controversial. AIM: To evaluate if lymph node micrometastasis is a significant independent prognostic factor and important risk factor for recurrence in gastric cancer. METHODS: A total of 1290 lymph nodes from 28 patients with gastric cancer, since 1998 until 2003, treated by radical resection (D2 and modified D3 lymphadenectomies were studied. Three sections per lymph node were stained by Hematoxilin-Eosin, histochemical (AB-PAS and immunohistochemical (AE1-AE3 techniques. Kaplan-Meier's survival curves and Log-rank/Cox tests were used in order to compares lymph node micrometastasis positivity, depth (pT and location of tumor in gastric wall, histologic type, lymphatic, vascular and perineural invasion, lymph node status (pN and stage. RESULTS: There were worse prognosis and recurrence in patients with positive lymph node micrometastasis related to vascular and perineural invasions, advanced lymph node status and advanced stages. CONCLUSION: Lymph node micrometastasis seems to be a significant independent prognostic factor and important risk factor for recurrence in gastric cancer, in a context of radical D2 lymphadenectomyRACIONAL: Micrometástases são um conjunto de células malignas dentro de linfonodo que não são detectadas pelos exames histopatológicos de rotina. Elas são relacionadas a prognóstico mais pobre em muitos estudos sobre câncer gástrico, mas a real significância dessas células permanece controversa. OBJETIVO: Avaliar se micrometástase linfonodal é um fator independente de prognóstico e importante para detectar a recurrência do câncer gástrico. MÉTODOS: Um total de 1290 lifonodos de 28 pacientes com câncer gástrico, de 1998 a 2003

  8. Information and Informality

    DEFF Research Database (Denmark)

    Larsson, Magnus; Segerstéen, Solveig; Svensson, Cathrin

    2011-01-01

    leaders on the basis of their possession of reliable knowledge in technical as well as organizational domains. The informal leaders engaged in interpretation and brokering of information and knowledge, as well as in mediating strategic values and priorities on both formal and informal arenas. Informal...... leaders were thus seen to function on the level of the organization as a whole, and in cooperation with formal leaders. Drawing on existing theory of leadership in creative and professional contexts, this cooperation can be specified to concern task structuring. The informal leaders in our study...... contributed to task structuring through sensemaking activities, while formal leaders focused on aspects such as clarifying output expectations, providing feedback, project structure, and diversity....

  9. Evolução e prognóstico materno-fetal da cirurgia cardíaca durante a gravidez Evolución y pronóstico materno-fetal de la cirugía cardiaca durante el embarazo Maternal-fetal outcome and prognosis of cardiac surgery during pregnancy

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    Walkiria Samuel Ávila

    2009-07-01

    Full Text Available FUNDAMENTO: A cirurgia cardíaca favorece o prognóstico materno em casos refratários à terapêutica clínica, contudo associa-se a riscos ao concepto quando realizada durante a gravidez. OBJETIVO: Analisar a evolução e o prognóstico materno-fetal de gestantes submetidas à cirurgia cardíaca no ciclo gravídico-puerperal. MÉTODOS: Estudou-se a evolução de 41 gestações de mulheres que tiveram indicação de cirurgia cardíaca no ciclo gravídico puerperal. A cardiotocografia fetal foi mantida durante o procedimento nas pacientes com idade gestacional acima de 20 semanas. RESULTADOS: A média da idade materna foi de 27,8 ± 7,6 anos, houve predomínio da valvopatia reumática (87,8%, e 15 dessas (41,6% foram submetidas à reoperação, devido à disfunção de prótese valvar. A média do tempo de circulação extracorpórea foi de 87,4 ± 43,6 min, e a hipotermia foi utilizada em 27 casos (67,5%. Treze mães (31,7% não apresentaram intercorrências e tiveram seus recém-nascidos vivos e saudáveis. A evolução pós-operatória das demais 28 gestações (68,3% mostrou: 17 complicações maternas (41,5%; três óbitos (7,3%; 12 perdas fetais (29,2% e quatro casos de malformação neurológica (10%, dois dos quais evoluíram para óbito tardio. Houve uma perda de seguimento após a cirurgia. Nove pacientes (21,9% foram operadas em caráter de emergência, situação que influenciou (p FUNDAMENTO: La cirugía cardiaca favorece el pronóstico materno en casos refractarios a la terapéutica clínica, sin embargo está asociada a riesgos cuando realizada durante el embarazo. OBJETIVO: Analizar la evolución y el pronóstico materno-fetal de gestantes sometidas a la cirugía cardiaca en el ciclo grávido puerperal. MÉTODOS: Se estudió la evolución de 41 gestaciones de mujeres que tuvieron indicación de cirugía cardiaca en el ciclo grávido puerperal. La cardiotocografía fetal se mantuvo durante el procedimiento en las pacientes con

  10. Terapia oclusiva em ambliopia: fatores prognósticos

    OpenAIRE

    Salata,Ana Carolina Fava; Villaça,Veridiana Toledo Nascimento; Roma,Renato Lopes; Norato,Denise Yvonne Janovitz; Carvalho,Keila Miriam Monteiro de

    2001-01-01

    Objetivos: Ambliopia é o defeito visual mais comum em crianças e por mais de 250 anos a terapia oclusiva vem sendo o melhor tratamento. Sendo assim, propusemo-nos a determinar os fatores que influenciam no sucesso do tratamento da ambliopia por terapia oclusiva em nosso meio. Métodos: Foi realizado um estudo retrospectivo com 169 crianças amblíopes atendidas no Ambulatório de Ambliopia do Hospital de Clínicas da UNICAMP, Campinas (SP), entre janeiro de 1996 e maio de 1998. A população atendid...

  11. Information Space, Information Field, Information Environment

    Directory of Open Access Journals (Sweden)

    Victor Ya. Tsvetkov

    2014-08-01

    Full Text Available The article analyzes information space, information field and information environment; shows that information space can be natural and artificial; information field is substantive and processual object and articulates the space property; information environment is concerned with some object and acts as the surrounding in relation to it and is considered with regard to it. It enables to define information environment as a subset of information space. It defines its passive description. Information environment can also be defined as a subset of information field. It corresponds to its active description.

  12. Prognosing the sex of adults of Amblyomma auricularium through evaluating the biological parameters of engorged nymphs Prognóstico do sexo dos adultos de Amblyomma auricularium através da avaliação de parâmetros biológicos de ninfas ingurgitadas

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    Michele da Costa Pinheiro

    2013-04-01

    originaram fêmeas demoraram em média 8,8±1,8dias para completar sua alimentação. Já o período de pré-ecdise foi mais curto para ninfas que originaram machos, 17,2±0,93dias, em relação às ninfas que originaram fêmeas, 17,7±1,00dias. Apesar de uma área de sobreposição dos pesos de ninfas ingurgitadas que originaram adultos machos e fêmeas, esse parâmetro é o mais confiável para o prognóstico do sexo dos adultos de A. auricularium.

  13. Psychological characteristics of mothers of patients with anorexia nervosa: implications for treatment and prognosis Características psicológicas de mães de pacientes com anorexia nervosa: implicações para o tratamento e prognóstico

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    Lia Keuchguerian Silveira Campos

    2012-01-01

    Full Text Available INTRODUCTION: The complexity of factors involved in anorexia nervosa (AN and the recommendations of prominent health organizations underscore the importance of reflecting on therapeutic interventions aimed at patients' family members. OBJECTIVE: To expand knowledge about the mother-daughter relationship in AN, with a focus on developing a conceptual framework that is able to improve the treatment of the disorder, reduce factors that perpetuate it and improve prognosis. METHOD: A clinical method, anchored by psychodynamic references, was employed in a group of family members of patients with eating disorders. The group met weekly, and sessions were led by psychologists from the eating disorder outpatient clinic of a university hospital. RESULTS AND DISCUSSION: Common characteristics in the mother-daughter relationship in cases of AN were identified. The issue of mutual control, the dialectic between omnipotence and impotence, and the relationship of devotion, passion and annihilation between mothers and daughters are phenomena that form the basis of AN, with a direct influence on the severity of each case and on treatment success. CONCLUSION: Our findings allowed us to identify important aspects in the mother-daughter relationship in AN, which may improve the clinical interventions aimed at treating the disorder.INTRODUÇÃO: A complexidade de fatores que compõem a anorexia nervosa (AN e as recomendações de importantes organizações ligadas à saúde torna fundamental uma reflexão acerca de propostas de intervenções psicoterapêuticas direcionadas aos familiares desses pacientes. OBJETIVO: Expandir o conhecimento acerca da relação mãe-filha na AN, visando desenvolver uma estrutura conceitual que aperfeiçoe o tratamento do transtorno, reduza os fatores que o mantêm e melhore o prognóstico. MÉTODO: Utilizou-se um método clínico de observação fundamentado em referenciais psicodinâmicos de um grupo de familiares de pacientes com

  14. Cardiotocografia Anteparto e Prognóstico Perinatal em Gestações Complicadas pelo Diabete: Influência do Controle Metabólico Materno Antepartum Nonstress Test and Perinatal Prognosis in Pregnancies Complicated by Diabetes: Influence of Maternal Metabolic Control

    Directory of Open Access Journals (Sweden)

    Moacyr Sanches Mascaro

    2002-10-01

    Full Text Available Objetivo: relacionar a qualidade do controle metabólico com os resultados da cardiotocografia (CTG anteparto e avaliar sua capacidade preditiva no prognóstico perinatal de gestações associadas ao diabete. Pacientes e Métodos: estudo retrospectivo de 125 gestantes, portadoras de diabete gestacional ou clínico, no qual se relacionou a última CTG anteparto (intervalo máximo de 48 horas à qualidade do controle metabólico materno e aos resultados perinatais. A qualidade do controle metabólico foi definida pela média glicêmica do dia do exame (MGd e da gestação (MG e pelo comportamento da requisição de insulina (R/insulina. Para os resultados perinatais foram analisados os índices de Apgar de 1º e 5º minuto, a classificação peso/idade gestacional, o tempo de internação, a necessidade de cuidados de UTI e a ocorrência de óbito neonatal (ONN precoce. A capacidade diagnóstica da CTG anteparto foi avaliada pelos índices de sensibilidade, especificidade e valor preditivo positivo e negativo. Resultados: a MGd adequada ( ou = 120 mg/dL, a 26,1% (pBackground: the antepartum nonstress test (NST is the most commonly used test to evaluate fetal well-being in pregnancies complicated by diabetes, its results being related to the quality of maternal metabolic control and perinatal prognosis. Purpose: to relate the quality of metabolic control to the results of the NST and to evaluate its predictive capacity for the perinatal prognosis of pregnancies associated with diabetes. Patients and Methods: this is a retrospective study of 125 pregnant women with gestational or clinical diabetes in which the last NST (maximum interval of 48 h was related to the quality of maternal metabolic control and perinatal results. Quality of metabolic control was defined by the glycemic mean on the test day (GMd, glycemic mean during pregnancy (GM, and behavior of insulin requirement (Insulin/R. For the perinatal results, the following parameters were

  15. Teste triplo biofísico: um novo parâmetro ultra-sonográfico para prognóstico em gestações iniciais Biophysical triple test: a new ultrasonographic parameter for prognostic evaluation in early pregnancies

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    Joaquim R. M. Coelho

    1999-01-01

    Full Text Available Objetivos: atrasos no desenvolvimento do saco gestacional (SG, no tamanho do botão embrionário (CCN, assim como freqüências cardíacas embrionárias (FCE baixas podem ser considerados fatores de mau prognóstico na evolução da gestação. O objetivo deste trabalho foi avaliar a utilização destes 3 parâmetros em conjunto, o que denominamos Teste Triplo Biofísico (TTB. Metodo: foram avaliadas 35 gestações únicas provenientes de fertilização assistida por injeção intracitoplasmática de espermatozóide (ICSI. Todos os exames de ultra-som foram realizados por um único examinador, após 4-5 semanas da transferência de embriões (6-7 semanas de gestação, com equipamento modelo Synergy da Diasonics, sonda transvaginal de 7,0 MHz. O SG foi medido em seu maior diâmetro transverso, o CCN foi medido no sentido sagital e a FCE pelo modo B-M e Doppler. Na análise estatística foi utilizado o teste de Fisher. Resultados: considerou-se como parâmetros alterados : SG Purpose: it has been demonstrated that delays in gestational sac development, in crown-rump length and low embryonic heart rate could be indicators of poor pregnancy outcome. The purpose was to evaluate the use of these three parameters together, which we named Biophysical Triple Test (BTT. Method: thirty-five singleton pregnancies following IVF treatment with intracytoplasmatic sperm injection (ICSI were studied. All ultrasonographic scans were performed by the same examiner, 4-5 weeks after embryo transference (6-7 week gestation, using a Diasonics equipment, model Synergy, with a 7.0-MHz transvaginal transducer. The gestational sac (GS was measured at the longest transverse diameter; the crown-rump length (CRL was measured at the sagittal plan and the embryonic heart rate (EHR was calculated from frozen B and M-mode and Doppler. The statistical test used was Fisher's test. Results: the following parameters were considered abnormal: GS < 15.4 mm, CRL < 3.9 mm, EHR < 100

  16. TIPS para o controle das complicações da hipertensão portal: eficácia, fatores prognósticos associados e variações técnicas TIPS for controlling portal hypertension complications: efficacy, predictors of outcome and technical variations

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    Néstor Hugo Kisilevzky

    2006-12-01

    Full Text Available OBJETIVO: Avaliar a eficácia do TIPS (transjugular intrahepatic portosystemic shunt para tratar as complicações clínicas em pacientes com hipertensão portal. MATERIAIS E MÉTODOS: Quarenta e quatro pacientes, sendo 30 do sexo masculino e 14 do feminino e com idade média de 52 anos foram analisados. A indicação para realização de TIPS foi hemorragia gastrintestinal em 28 e ascite refratária em 16. Houve 7 pacientes Child-Pugh A, 24 Child-Pugh B e 11 Child-Pugh C. RESULTADOS: O TIPS foi realizado com sucesso em todos os pacientes (100%, verificando-se queda do gradiente pressórico porto-sistêmico médio de 49,69% (de 18,98 mmHg para 9,55 mmHg. Comprovou-se melhora clínica em 35 pacientes (79,55%. A mortalidade pós-operatóriaia foi de 13,64%, sendo mais incidente nos pacientes Child-Pugh C (45,45%. Os fatores mais relevantes de mau prognóstico foram o aumento da bilirrubina e do nível de creatinina. A sobrevida média de pacientes Child-Pugh A foi de 11,5 meses, nos Child-Pugh B foi de 10,97 meses e nos Child-Pugh C foi de apenas 5,9 meses. Foram observadas complicações em nove casos (20,44%. CONCLUSÃO: O TIPS é eficiente para reduzir a pressão portal. As complicações e a morbi-mortalidade relacionadas com o procedimento podem ser consideradas aceitáveis. A mortalidade foi influenciada por alguns fatores clínicos, tais como classe Child-Pugh C e elevação dos níveis séricos de bilirrubina e creatinina.OBJECTIVE: To evaluate the efficacy of TIPS (transjugular intrahepatic portosystemic shunt for resolving clinical complications in patients with portal hypertension. MATERIALS AND METHODS: Forty-four caucasian patients, 30 men and 14 women, with a mean age of 52 years have been evaluated. Indication for TIPS has been gastrointestinal hemorrhage in 28 patients, and refractory ascites in 16. There has been 7 Child-Pugh A patients, 24 Child-Pugh B, and 11 Child-Pugh C. RESULTS: TIPS was successfully performed in all the

  17. Avaliação prognóstica da doença coronária estável através de um novo escore Evaluación pronóstica de la enfermedad coronaria estable a través de un nuevo score New prognostic score for stable coronary disease evaluation

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    Fernanda Coutinho Storti

    2011-05-01

    Full Text Available FUNDAMENTO: A necessidade de melhorar a acurácia do teste de esforço, determinou o desenvolvimento de escores, cuja aplicabilidade já foi amplamente reconhecida. OBJETIVO: Avaliação prognóstica do coronariopata estável através de um novo escore simplificado. MÉTODOS: Um novo escore foi aplicado em 372 coronariopatas multiarteriais e função ventricular preservada, 71,8% homens, idade média 59,5 (± 9,07 anos, randomizados para angioplastia, revascularização cirúrgica e tratamento clínico, acompanhados por 5 anos. Óbito cardiovascular foi o desfecho primário. Infarto do miocárdio não-fatal, óbito e re-intervenção formaram o desfecho combinado secundário. O escore baseou-se numa equação previamente validada resultante da soma de 1 ponto para: sexo masculino, história de infarto, angina, diabete, uso de insulina e ainda 1 ponto para cada década de vida a partir dos 40 anos. Teste positivo adicionou 1 ponto. RESULTADOS: Ocorreram 36 óbitos (10 no grupo angioplastia, 15 no grupo revascularização e 11 no grupo clínico, p = 0,61. Observou-se 93 eventos combinados: 37 no grupo angioplastia, 23 no grupo revascularização e 33 no grupo clínico (p = 0,058. 247 pacientes apresentaram escore clínico > 5 pontos e 216 > 6 pontos. O valor de corte > 5 ou > 6 pontos identificou maior risco, com p = 0,015 e p = 0,012, respectivamente. A curva de sobrevida mostrou uma incidência de óbito após a randomização diferente naqueles com escore > 6 pontos (p = 0,07, e uma incidência de eventos combinados diferente entre pacientes com escore 6 pontos (p = 0,02. CONCLUSÃO: O novo escore demonstrou consistência na avaliação prognóstica do coronariopata estável multiarterial.FUNDAMENTO: La necesidad de mejorar la exactitud de las pruebas de estrés, determinó el desarrollo de los puntajes, cuya aplicación fue ampliamente reconocida. OBJETIVO: La evaluación pronóstica del coronariópata estable a través de un nuevo score

  18. Information management

    Science.gov (United States)

    Ricks, Wendell; Corker, Kevin

    1990-01-01

    Primary Flight Display (PFD) information management and cockpit display of information management research is presented in viewgraph form. The information management problem in the cockpit, information management burdens, the key characteristics of an information manager, the interface management system handling the flow of information and the dialogs between the system and the pilot, and overall system architecture are covered.

  19. Information Crisis

    CERN Document Server

    Losavio, Michael

    2012-01-01

    Information Crisis discusses the scope and types of information available online and teaches readers how to critically assess it and analyze potentially dangerous information, especially when teachers, editors, or other information gatekeepers are not available to assess the information for them. Chapters and topics include:. The Internet as an information tool. Critical analysis. Legal issues, traps, and tricks. Protecting personal safety and identity. Types of online information.

  20. Trissomia 18: revisão dos aspectos clínicos, etiológicos, prognósticos e éticos Trisomía 18 (síndrome de Edwards: revisión de los aspectos clínicos, etiológicos, pronósticos y éticos Trisomy 18: review of the clinical, etiologic, prognostic, and ethical aspects

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    Rafael Fabiano M. Rosa

    2013-03-01

    Full Text Available OBJETIVO: Revisar as características clínicas, etiológicas, diagnósticas e prognósticas da trissomia do cromossomo 18 (síndrome de Edwards. FONTES DE DADOS: Foram pesquisados artigos científicos presentes nos portais MedLine, Lilacs e SciELO, utilizando-se os descritores 'trisomy 18' e 'Edwards syndrome'. A pesquisa não se limitou a um período determinado e englobou artigos presentes nestes bancos de dados. SÍNTESE DOS DADOS: A síndrome de Edwards é uma doença caracterizada por um quadro clínico amplo e prognóstico bastante reservado. Há descrição na literatura de mais de 130 anomalias diferentes, as quais podem envolver praticamente todos os órgãos e sistemas. Seus achados são resultantes da presença de três cópias do cromossomo 18. A principal constituição cromossômica observada entre estes pacientes é a trissomia livre do cromossomo 18, que se associa ao fenômeno de não disjunção, especialmente na gametogênese materna. A maioria dos fetos com síndrome de Edwards acaba indo a óbito durante a vida embrionária e fetal. A mediana de sobrevida entre nascidos vivos tem usualmente variado entre 2,5 e 14,5 dias. CONCLUSÕES: O conhecimento do quadro clínico e do prognóstico dos pacientes com a síndrome de Edwards tem grande importância no que diz respeito aos cuidados neonatais e à decisão de instituir ou não tratamentos invasivos. A rapidez na confirmação do diagnóstico é importante para a tomada de decisões referentes às condutas médicas. Muitas vezes, as intervenções são realizadas em condições de emergência, sem muita oportunidade de reflexão ou discussão, e envolvem questões médicas e éticas difíceis.OBJETIVO: Revisar las características clínicas, etiológicas, diagnósticas y pronósticas de la trisomía del cromosoma 18 (síndrome de Edwards. FUENTES DE DATOS: Fueron investigados artículos científicos presentes en los portales MedLine, Lilacs y SciELO, utilizando los

  1. Analysis of the immunohistochemical expressions of p53, bcl-2 and Ki-67 in colorectal adenocarcinoma and their correlations with the prognostic factors Análise das expressões imunoistoquímicas da p53, bcl-2 e Ki-67 no adenocarcinoma colorretal e suas correlações com os fatores prognósticos

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    Hunaldo Lima de Menezes

    2010-06-01

    indicarem a resposta ao tratamento e a recurrência da neoplasia. OBJETIVO: Analisar as expressões imunoistoquímicas das proteínas p53, bcl-2 e Ki-67 no adenocarcinoma colorretal, correlacionando-as com os fatores prognósticos clínico-patológicos. MÉTODO: Foram confeccionados blocos de parafina de TMA com tecido de adenocarcinoma colorretal ressecados cirurgicamente em 82 pacientes no Hospital São Paulo da Universidade Federal der São Paulo, São Paulo, SP, de 2002 a 2005, não submetidos a radio ou quimioterapia. Cortes de 4 µm foram submetidos a reação imunoistoquímica e obtidos escores de intensidade das imunoexpressões, que foram correlacionados com o grau de diferenciação celular, estádio, tempo livre de doença, recidiva, sobrevida e mortalidade específica. As variáveis do estudo foram analisadas pelos testes do qui ao quadrado e de Kaplan-Meier para verificar as associações com os marcadores. A significância das diferenças entre as curvas do tempo livre de doença e da sobrevida foi analisada pelos testes de Logrank e Wilcoxon. RESULTADOS: A expressão imunoistoquímica da p53 foi positiva em 70 tumores (85,4% e negativa em 12 (14,6%. A bcl-2 foi positiva em 26 tumores (31,7% e negativa em 56 (68,3%. A expressão imunoistoquímica da Ki-67 foi positiva em 62 tumores (75,6%, sendo em 20 (24,4% negativa. Não houve correlação estatisticamente significante entre as expressões imunoistoquímicas dos marcadores analisadas separadamente ou em conjunto, envolvendo o grau de diferenciação celular, estádio, tempo livre de doença, sobrevida e mortalidade específica. Com relação à recidiva, observou-se correlação estatisticamente significante com a expressão imunoistoquímica positiva da Ki-67 (P = 0,035. CONCLUSÃO: A expressão imunoistoquímica positiva da Ki-67 no câncer colorretal está relacionada com a incidência de recidiva da doença.

  2. Expressão da MMP-9 e do VEGF no câncer de mama: correlação com outros indicadores de prognóstico Expression of MMP-9 and VEGF in breast cancer: correlation with other prognostic indicators

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    Flavio Cabreira Jobim

    2008-06-01

    Full Text Available OBJETIVO: analisar a expressão da metaloproteinase da matriz 9 (MMP-9 e do fator de crescimento vascular endotelial (VEGF em um grupo de pacientes com câncer primário de mama, e correlacioná-los entre si e com outros indicadores de prognóstico. MÉTODOS: estudo transversal que analisou a expressão da MMP-9 e do VEGF em 88 casos consecutivos de tumores primários de mama. As amostras foram obtidas de pacientes portadoras de câncer primário de mama, submetidas a tratamento cirúrgico no Hospital de Clínicas de Porto Alegre da Universidade Federal do Rio Grande do Sul, no período de janeiro de 2000 a dezembro de 2004. A técnica de imuno-histoquímica, usando o complexo avidina-biotina-peroxidase, foi aplicada para avaliar a imunoreação dos antígenos nos tumores. A expressão qualitativa das proteínas foi avaliada por meio da observação da intensidade da coloração acastanhada dos anticorpos no citoplasma das células malignas, considerando positiva quando pelo menos uma célula tumoral apresentava coloração nítida e inequívoca para cada um destes marcadores. Para a determinação do escore qualitativo (0=ausente, 1=fraca, 2=média e 3=forte, foi considerada a intensidade da coloração citoplasmática mais forte na lâmina, independente do número de células coradas. A expressão quantitativa foi determinada pela percentagem média de células coradas, observadas em pelo menos dez campos microscópicos. A quantificação final da expressão da MMP-9 e do VEGF foi feita por meio da aplicação do algoritmo HSCORE=Σ[(I+1]xPC, no qual I e PC representam a intensidade da coloração e a percentagem das células coradas, respectivamente. RESULTADOS: a MMP-9 e o VEGF apresentaram alto percentual de positividade nos tumores estudados. A expressão final mostrou escore mediano de 180 e 190, respectivamente. Quando se comparou a expressão da MMP-9 e do VEGF com as variáveis "idade", "diâmetro tumoral", "tipo histológico", "grau

  3. Idade como fator prognóstico no câncer de mama em estádio inicial Edad como factor pronóstico en el cáncer de mama en fase inicial Age as a prognostic factor in early breast cancer

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    Bernardo Garicochea

    2009-04-01

    Full Text Available OBJETIVO: Analisar a idade como fator prognóstico no câncer de mama em estádio clínico inicial. MÉTODOS: Estudo retrospectivo que analisou as características clínicas e a sobrevida livre de doença de 280 pacientes entre 25 e 81 anos com câncer de mama estágio clínico I e II com acompanhamento em hospital de Porto Alegre (RS, de 1995 a 2000. Dados clínicos, patológicos, tratamento e desfechos foram extraídos dos prontuários das pacientes. As pacientes foram divididas em dois grupos conforme a idade ao diagnóstico (40 anos. Os dois grupos foram comparados quanto ao estágio clínico, histologia, expressão de receptores hormonais, terapia e radioterapia utilizando o teste qui-quadrado e/ou exato de Fisher e para análise de sobrevida, o teste de long-rank e método de Kaplan-Meier. RESULTADOS: Do total de 280 mulheres estudadas, 54 (19,3% tinham até 40 anos de idade. Ambos os grupos de pacientes eram similares em estágio clínico, histologia e expressão de receptores hormonais. A proporção de pacientes com sobrevida livre de doença em seguimento de 56 meses foi significativamente maior nas pacientes acima de 40 anos (84% versus 70%. Proporcionalmente, as pacientes mais jovens receberam mais terapia adjuvante (88,8% versus 77,8%. Houve diferença significativa na probabilidade das mulheres acima de 40 anos de permanecerem livre de doença (84%, sendo mais evidente quando comparadas às pacientes com OBJETIVO: Analizar la edad como factor pronóstico en el cáncer de mama en fase clínico inicial. MÉTODOS: Estudio retrospectivo que analizó las características clínicas y la sobrevida libre de enfermedad de 280 pacientes entre 25 y 81 años con cáncer de mama fase clínica I y II con acompañamiento en hospital de Porto Alegre (Sur de Brasil, de 1995 a 2000. Datos clínicos, patológicos, tratamiento y resultados fueron extraídos de los prontuarios de las pacientes. Las pacientes fueron divididas en dos grupos conforme la

  4. Importância da proteína C-reativa no diagnóstico e no prognóstico intra-hospitalar em pacientes com dor torácica na sala de emergência C-reactive protein diagnostic and prognostic value in patients presenting at the emergency room with chest pain

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    Alfredo Antonio Potsch

    2006-09-01

    Full Text Available OBJETIVO: Testar os valores diagnóstico e prognóstico imediatos da proteína C-reativa (PCR nos pacientes admitidos na sala de emergência (SE com dor torácica (DT e sem elevação do segmento ST no eletrocardiograma (ECG. MÉTODOS: De janeiro de 2002 a dezembro de 2003, 980 pacientes consecutivos foram atendidos com DT suspeita de síndrome coronariana aguda na SE (idade = 64,9 ± 14,3 anos, homens = 55%, diabéticos = 18%, ECG normal = 84%. Dosou-se a PCR na admissão, a creatinofosfoquinase MB fração massa (CKMB e a troponina I seriadas, além de se registrar ECG seriados. As medidas da PCR foram padronizadas (PCR-p pelo valor do limite superior da normalidade (LSN do teste utilizado (3,0 mg/L para a PCR de alta sensibilidade-PCR-AS e 0,1 mg/dl para PCR titulada-PCR-t. RESULTADOS: Foi diagnosticado infarto agudo do miocárdio (IAM em 125 pacientes, e seus valores para a PCR-p foram 1,31 ± 2,90 (mediana = 0,47 versus 0,79 ± 1,39 (0,30 nos sem IAM (p = 0,031. A PCR-p > 1,0 apresentou sensibilidade de 30%, especificidade de 80,4%, valores preditivos positivo e negativo de 6,1% e de 96,7%, para o diagnóstico de IAM. Houve quarenta eventos cardíacos intra-hospitalares (óbitos = dezesseis, revascularizações de urgência = 22, IAM = dois. No 1º quartil da PCR-p ( 0,93 ocorreram quinze eventos (p = 0,003. Na regressão logística foram preditores independentes para eventos cardíacos a insuficiência ventricular esquerda, o sexo masculino e a PCR-p > 0,32, com razão de chances de 7,6, 2,8 e 2,2, respectivamente. CONCLUSÃO: Nos pacientes atendidos com DT na SE, a PCR-p: 1 Não foi um bom marcador de IAM, apesar de um valor normal praticamente afastar esse diagnóstico; 2 Um valor superior a um terço do seu limite superior da normalidade (LSN (>1 mg/L da PCR-AS ou >0,33 mg/dl da PCR-t foi preditor de eventos cardíacos adversos intra-hospitalares.OBJECTIVE: To test immediate diagnostic and prognostic values of C-reactive protein (CRP in

  5. Correlation between the immunohistochemical expressions of MMP-1, MMP-7 and VEGF and prognostic factors in colorectal adenocarcinoma Correlação entre as expressões imunohistoquímicas da MMP-1, MMP-7 e do VEGF no adenocarcinoma colorretal com fatores prognósticos

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    Edmundo Guilherme de Almeida Gomes

    2009-08-01

    Full Text Available PURPOSE: To analyze the expression of metalloproteinase-1, metalloproteinase-7 and vascular endothelial growth factor (VEGF in colorectal adenocarcinoma, and to correlate these with the clinical-pathological prognostic factors. METHODS: Tumor tissue from 82 patients was fixed in formalin and embedded in paraffin blocks. These samples were analyzed by means of the streptavidin-biotin immunohistochemical method, using the tissue microarray technique. Marker positivity was evaluated using categorical scores that determined cutoff percentages of stained tumor cells. Protein tissue expression was correlated with the variables of degree of cell differentiation, staging, disease-free interval, recurrence, survival and specific mortality. The Fisher exact and Kaplan-Meier tests were used to assess associations between the markers and the study variables. The log-rank and Wilcoxon tests were used to assess the significance of differences between curves of disease-free interval and survival. RESULTS: All tumors were positive for metalloproteinase-1; 50 (61% were positive and 32 (39% were negative for metalloproteinase-7; and 60 (74.1% were positive and 21 (25.9% were negative for VEGF. Correlation of marker expression, both in groups and individually, did not show statistical significance in relation to the degree of cell differentiation, staging, disease-free interval, survival or specific mortality. Recurrence showed a statistically significant correlation with positive expression of the three markers, when analyzed as a group (p = 0.038. CONCLUSION: The associated expression of metalloproteinase-1, metalloproteinase-7 and VEGF in colorectal adenocarcinoma is related to the incidence of disease recurrence.OBJETIVO: Analisar as expressões da metaloproteinase-1, metaloproteinase-7 e do fator de crescimento endotelial vascular no adenocarcinoma colorretal e correlacionar com os fatores prognósticos clínico-patológicos. MÉTODOS: Foram analisados

  6. New proposal for the treatment of poor prognosis young patients with advanced stage diffuse large B-cell lymphoma Nova proposta de tratamento no linfoma difuso de grandes células B no paciente jovem de mau prognóstico em estágio avançado

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    Sergio Cortelazzo

    2008-06-01

    ão associadas em uma melhoria da evolução clinica, particularmente dos pacientes que não apresentam fatores prognósticos adversos. Pacientes com risco pobre e com a idade ao redor dos 60 a 65 anos podem se beneficiar da combinação de dose ou do regime de dose intensificada mais rituximab. Pacientes jovens com risco pobre e que são definidos com IPI aa de 2 ou 3 e idade inferior a 60 anos são caracterizados como verdadeiramente refratários, sendo isto evidenciado pela progressão durante ou precocemente após o tratamento ou apresentam resposta tardia. Deve-se atentar para a modificação do tratamento e incluir imunoterapia para melhorar a taxa de resposta e reduzir a proporção de pacientes com doença em progressão. Atualmente a melhor sobrevida de progressão foi de 51%. Devemos observar aspectos alvissareiros da diminuição da alta resistência e da taxa de recaída nos programas de quimioterapia seqüenciais de altas doses com rituximab e o transplante autólogo de células-tronco. O grupo italiano elaborou um estudo prospectivo randomizado de fase III comparando a eficácia e a segurança da dose intensa de CHOP mais rituximab com altas doses seqüenciais e rituximab seguido do transplante autólogo. Dados preliminares já mostram que os programas intensificados e o transplante autólogo são factíveis ate 65 anos com bom manuseio do efeito tóxico em todos os centros participantes.

  7. Determinantes clínicos com influência no prognóstico da discectomia lombar: análise multifatorial Determinantes clínicos que influyen en el pronóstico de la disectomía lumbar: análisis multifactorial Clinical determinants' influence on lumbar discectomy prognosis: multi-factor analysis

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    Paulo Jorge Da Rocha Carvalho

    2010-03-01

    Full Text Available A seleção e o agendamento temporal inadequados dos pacientes permanecem as causas mais importantes de insucesso da cirurgia discal lombar. OBJETIVO: Este trabalho pretende avaliar os resultados clínicos e os factores preditivos que influenciam o prognóstico dos pacientes submetidos à discectomia lombar através de um modelo analítico multifatorial. MÉTODOS: Apresentamos uma série prospectiva de 68 pacientes com hérnias discais lombares que foram submetidos à discectomia entre 2003 e 2007. O seguimento médio foi de 3,9±0,1 anos. Os resultados clínicos foram avaliados utilizando o escore JOA (Japonese Orthopaedic Association Assessment Scoring System (JOA=29. RESULTADOS: Resultados pós-operatórios bom e excelente foram obtidos em 75% dos casos. Pacientes do sexo masculino e a preponderância de sintomas subjectivos sobre sintomas clínicos estiveram associados com os melhores resultados clínicos e com o retorno mais precoce à actividade laboral. O tempo de espera pela cirurgia não teve influência no resultado final. A necessidade de cirurgia foi questionada na ausência de défices neurológicos significativos (JOA para resultados clínicos >3/6. Um valor JOA pré-operatório >15 (debilidade inicial baixa está correlacionado com piores resultados clínicos pós-operatórios. CONCLUSÕES: O escore JOA é de fácil aplicação para clínicos e pacientes, uniformiza dados subjectivos e apresenta valor preditivo para os resultados dos pacientes submetidos à discectomia lombar.La selección y la agenda temporal inadecuada de los enfermos permanecen como las causas más importantes de la falta de éxito en la cirugía discal lumbar. OBJETIVO: este trabajo pretende evaluar los resultados clínicos y los factores predictivos que influyen en el pronóstico de los pacientes sometidos a la discectomía lumbar por medio de un modelo analítico multifatorial. MÉTODOS: se presenta una serie prospectiva de 68 pacientes con hernias discales

  8. Social information

    Directory of Open Access Journals (Sweden)

    Luiz Fernando de Barros Campos

    Full Text Available Based on Erving Goffman's work, the article aims to discuss a definition of information centered on the type conveyed by individuals in a multimodal way, encompassing language and body in situations of co-presence, where face-to-face interaction occurs, and influencing inter-subjective formation of the self. Six types of information are highlighted: material information, expressive information, ritualized information, meta-information, strategic information, and information displays. It is argued that the construction of this empirical object tends to dissolve the tension among material, cognitive and pragmatic aspects, constituting an example of the necessary integration among them. Some vulnerable characteristics of the theory are critically mentioned and it is suggested that the concept of information displays could provide a platform to approach the question of the interaction order in its relations with the institutional and social orders, and consequently, to reassess the scope of the notion of social information analyzed.

  9. Information Concepts

    CERN Document Server

    Marchionini, Gary

    2010-01-01

    Information is essential to all human activity, and information in electronic form both amplifies and augments human information interactions. This lecture surveys some of the different classical meanings of information, focuses on the ways that electronic technologies are affecting how we think about these senses of information, and introduces an emerging sense of information that has implications for how we work, play, and interact with others. The evolutions of computers and electronic networks and people's uses and adaptations of these tools manifesting a dynamic space called cyberspace. O

  10. Information Myopia

    Directory of Open Access Journals (Sweden)

    Nadi Helena Presser

    2016-04-01

    Full Text Available This article reflects on the ways of appropriation in organizations. The notion of Information Myopia is characterized by the lack of knowledge about the available informational capabilities in organizations, revealing a narrow view of the information environment. This analysis has focused on the process for renewing the software licenses contracts of a large multinational group, in order to manage its organizational assets in information technology. The collected, explained and justified information allowed to elaborate an action proposal, which enabled the creation of new organizational knowledge. In its theoretical dimension, the value of information was materialized by its use, in a collective process of organizational learning.

  11. Information cultures

    DEFF Research Database (Denmark)

    Skouvig, Laura

    2017-01-01

    The purpose of this article is to suggest a genealogy of the concept of information beyond the 20th century. The article discusses how the concept of information culture might provide a way of formulating such a genealogic strategy. The article approaches this purpose by providing a general...... narrative of premodern information cultures, examining works on early-modern scholars and 18th century savants and discussion of what seems to be a Foucauldian rupture in the conceptualization of information in 19th century England. The findings of the article are situated in the thinking that a genealogy...... of information would reveal that information had specific purposes in specific settings....

  12. INFORMATION MANAGERx

    African Journals Online (AJOL)

    USER

    Use of Online Information Sources in Federal University Medical Libraries in North West Geo-Political Zone of Nigeria. By ... on the quality of information services provided to clients. .... North West Zone need to identify the importance of.

  13. Informational Urbanism

    Directory of Open Access Journals (Sweden)

    Wolfgang G. Stock

    2015-10-01

    Full Text Available Contemporary and future cities are often labeled as "smart cities," "ubiquitous cities," "knowledge cities" and "creative cities." Informational urbanism includes all aspects of information and knowledge with regard to urban regions. "Informational city" is an umbrella term uniting the divergent trends of information-related city research. Informational urbanism is an interdisciplinary endeavor incorporating on the one side computer science and information science and on the other side urbanism, architecture, (city economics, and (city sociology. In our research project on informational cities, we visited more than 40 metropolises and smaller towns all over the world. In this paper, we sketch the theoretical background on a journey from Max Weber to the Internet of Things, introduce our research methods, and describe main results on characteristics of informational cities as prototypical cities of the emerging knowledge society.

  14. Copyright Information

    Science.gov (United States)

    ... Here: Home → Copyright Information URL of this page: https://medlineplus.gov/copyright.html Copyright Information To use ... the Magazine and NIH MedlinePlus Salud The FAQs ( https://medlineplus.gov/faq/faq.html ) The same content ...

  15. Information Literacy

    African Journals Online (AJOL)

    ian

    The paper also discusses some challenges faced in the teaching ... groups, language and cultural barriers and time and lack of computers. The paper ... administrative staff, researchers and librarians work with information. ...... The role of Information and Communication Technologies in Harnessing Information for women in.

  16. Informal Taxation.

    Science.gov (United States)

    Olken, Benjamin A; Singhal, Monica

    2011-10-01

    Informal payments are a frequently overlooked source of local public finance in developing countries. We use microdata from ten countries to establish stylized facts on the magnitude, form, and distributional implications of this "informal taxation." Informal taxation is widespread, particularly in rural areas, with substantial in-kind labor payments. The wealthy pay more, but pay less in percentage terms, and informal taxes are more regressive than formal taxes. Failing to include informal taxation underestimates household tax burdens and revenue decentralization in developing countries. We discuss various explanations for and implications of these observed stylized facts.

  17. Informal Taxation*

    Science.gov (United States)

    Olken, Benjamin A.; Singhal, Monica

    2011-01-01

    Informal payments are a frequently overlooked source of local public finance in developing countries. We use microdata from ten countries to establish stylized facts on the magnitude, form, and distributional implications of this “informal taxation.” Informal taxation is widespread, particularly in rural areas, with substantial in-kind labor payments. The wealthy pay more, but pay less in percentage terms, and informal taxes are more regressive than formal taxes. Failing to include informal taxation underestimates household tax burdens and revenue decentralization in developing countries. We discuss various explanations for and implications of these observed stylized facts. PMID:22199993

  18. Microneurografia e pletismografia de oclusão venosa na insuficiência cardíaca: correlação com prognóstico Microneurografía y pletismografía de oclusión venosa en la insuficiencia cardiaca: correlación con pronóstico Microneurography and venous occlusion plethysmography in heart failure: correlation with prognosis

    Directory of Open Access Journals (Sweden)

    Robinson Tadeu Munhoz

    2009-01-01

    Full Text Available FUNDAMENTO: Microneurografia e pletismografia de oclusão venosa podem ser considerados métodos de avaliação da atividade simpática. OBJETIVO: Avaliar a intensidade da atividade simpática através da microneurografia e da pletismografia de oclusão venosa em pacientes com insuficiência cardíaca, e correlacionar essa intensidade com prognóstico. MÉTODOS: 52 pacientes com insuficiência cardíaca (FE 53,5 impulsos/min para ANSM (S=90,55. E=73,68% e 1,81 ml/min/100gr (PFUNDAMENTO: Microneurografía y pletismografía de oclusión venosa se pueden considerar como métodos de evaluación de la actividad simpática. OBJETIVO: Evaluar la intensidad de la actividad simpática a través de la microneurografía y de la pletismografía de oclusión venosa en pacientes con insuficiencia cardiaca, y correlacionar esa intensidad con pronóstico. MÉTODOS: Un total de 52 pacientes con insuficiencia cardiaca (FE 53,5 impulsos/min para ANSM (S=90,55. E=73,68% y 1,81 ml/min/100gr (PBACKGROUND: Microneurography and venous occlusion plethysmography can be considered methods of assessment of the sympathetic activity. OBJECTIVE: To evaluate the intensity of the sympathetic activity through microneurography and venous occlusion plethysmography in patients with heart failure (HF and correlate this intensity with prognosis. METHODS: 52 patients with HF (ejection fraction 53.5 impulses/min for MSNA (S=90.55. E=73.68% and 1.81 ml/min/100gr (P<0.001. Logistic regression analysis: the higher the MSNA and the lower the MBF, the higher is the probability of death. CONCLUSION: The intensity of the MSNA and the MBF can be considered prognostic markers in advanced HF.

  19. Information Trust

    OpenAIRE

    Atele-Williams , Tosan; Marsh , Stephen

    2017-01-01

    Part 7: IFIPTM 2017 Graduate Symposium; International audience; Information has been an essential element in the development of collaborative and cooperative models, from decision making to the attainmentof varying goals, people are adept at making judgment on the trustworthiness of information, based on knowledge and understanding of a normative model of information. Contemporary narrative especially in high-impact contexts like politics, health, business, government and technology, is erodi...

  20. Transfusão sangüínea no intra-operatório, complicações e prognóstico Transfusión sanguínea en el intraoperatorio, complicaciones y pronóstico Complications and prognosis of intraoperative blood transfusion

    Directory of Open Access Journals (Sweden)

    João Manoel Silva Junior

    2008-10-01

    mortalidade. Os escores APACHE II, POSSUM e maior número de transfusões foram fatores de riscos independentes de pior prognóstico no pós-operatório.JUSTIFICATIVA Y OBJETIVOS: Transfusiones sanguíneas en el intraoperatorio están asociadas al aumento de complicaciones en el postoperatorio y costes hospitalarios. Por tanto, este estudio evaluó las características, complicaciones y los posibles factores de riesgos para muerte en pacientes quirúrgicos que necesitaron transfusiones sanguíneas en el intraoperatorio. MÉTODO: Categoría prospectiva, durante el período de un año, en el centro quirúrgico de hospital terciario. Se incluyeron pacientes con edad por encima de los 18 años que necesitaron transfusiones sanguíneas en el intraoperatorio. Testigos de Jeová, pacientes que recibieron transfusiones previas, fracaso coronario y lesión encefálica aguda quedaron excluidos del estudio. RESULTADOS: El estudio involucró a 80 pacientes, con una edad promedio entre los 68,4 ± 14,1 años. Los pacientes ASA II eran prevalecientes con 69,6% de los casos, las puntuaciones APACHE II y POSSUM fueron, como promedio respectivamente de 13,6 ± 4,4 y 37,5 ± 11,4. La hemoglobina promedio al momento de la transfusión era de 8,2 ± 1,8 g.dL-1 y un 19% de los pacientes tuvieron hemoglobina por encima de 10 g.dL-1. Los pacientes recibieron como promedio 2,2 ± 0,9 UI de concentrados de hematíes. La mortalidad hospitalaria fue de un 26,3%. Las complicaciones postransfusiones totalizaron un 57,5% de los casos en el postoperatorio y la más frecuente fue la infección. Fueron factores independientes de muerte en la regresión logística las puntuaciones APACHE II (OR = 1,34; IC 95% 1,102-1,622, POSSUM (OR = 1,08; IC 95% 1,008 - 1,150 y número de unidades de concentrados de hematíes recibidos (OR = 2,22; IC 95% 1,100 - 4,463. Mientras mayor es el número de transfusiones sanguíneas, mayores son las incidencias de las complicaciones y de la mortalidad. CONCLUSIONES: El valor de la

  1. Information circulars

    International Nuclear Information System (INIS)

    1997-02-01

    The document summarizes the Information Circulars published by the IAEA for the purpose of bringing matters of general interest to the attention of all Member States. This revision contains INFCIRCs published up to February 1997, grouped by field of activity. A complete list of information circulars in numerical order is given in an annex

  2. Information circulars

    International Nuclear Information System (INIS)

    2002-05-01

    Information circulars are published from time to time under the symbol INFCIRC/... for the purpose of bringing matters of general interest to the attention of all Members of the Agency. The present revision contains INFCIRCs published up to the end of April 2002. A complete numerical list of information circulars is reproduced with their titles in the Annex

  3. Information circulars

    International Nuclear Information System (INIS)

    1999-06-01

    The document summarizes the Information Circulars published by the IAEA for the purpose of bringing matters of general interest to the attention of all Member States. This revision contains INFCIRCs published up to the end of May 1999, grouped by field of activity. A complete list of information circulars in numerical order is given in an annex

  4. Information circulars

    International Nuclear Information System (INIS)

    1994-08-01

    Information circulars are published from time to time under the symbol INFCIRC/... for the purpose of bringing matters of general interest to the attention of all Members of the Agency. The present revision contains INFCIRCs published up to mid-August 1994. A complete numerical list of information circulars is reproduced with their titles in the Annex

  5. Information circulars

    International Nuclear Information System (INIS)

    1992-08-01

    The document summarizes the Information Circulars published by the IAEA for the purpose of bringing matters of general interest to the attention of all Members of the Agency. This revision contains INFCIRCs published up to mid-August 1992. A complete numerical lift of Information Circulars with their titles is reproduced in an Annex

  6. INFORMATION MANAGERx

    African Journals Online (AJOL)

    USER

    This study investigated the effectiveness and impact of library instruction (GST 111 – the use of ... information literacy of the students for lifelong .... competency of freshman business students of a ... strategies, information sources, proper use of library ..... P. Remark. Library skill. Secondary school attended. 47.5846. 01.3600.

  7. Relação da expressão de fatores de crescimento celular (IGF-1 e (SCF com fatores prognósticos e o alvo da rapamicina em mamíferos (m-TOR em mastocitomas cutâneos caninos IGF-1 and SCF protein expression in cutaneous mast cell tumors in dogs and relation to prognostic factors and mammalian target of rapamycin (m-TOR

    Directory of Open Access Journals (Sweden)

    Raquel B. Ferioli

    2013-04-01

    Full Text Available O mastocitoma cutâneo (MTC é a neoplasia maligna mais comum na pele dos cães e seu comportamento biológico é muito variável. Dentre os fatores prognósticos estudados nos MTCs, a classificação histopatológica, o índice proliferativo e o padrão de expressão doc-KIT são os que apresentam uma associação mais relevante com o provável prognóstico deste tumor. O objetivo deste trabalho foi avaliar a expressão proteica de fator de crescimento semelhante à insulina tipo 1 (IGF-1, fator de célula tronco (SCF e sua relação com o receptor tirosina quinase (c-KIT, alvo da rapamicina em mamíferos (m-TOR, grau histológico, índice proliferativo pelo KI-67e o número de figuras de mitose (IM com dados clínicos de cães com MTCs . Foram utilizadas 133 amostras de MTCs, provenientes de 133 cães, dispostas em lâminas de microarranjo de tecidos (TMA. A técnica de imuno-histoquímica foi utilizada para a avaliação destas proteínas. Observou-se associação entre SCF e, a graduação histopatológica proposta em 2011, índice mitótico, proliferação celular (KI-67, escore de IGF-1, local da lesão, idade dos animais e padrão imuno-histoquímico do receptor c-KIT. A relação de dependência também foi observada entre IGF-1 e o porte dos animais, IM, m-TOR e c-KIT. A expressão de SCF teve relacção com a agressividade dos MTCs caninos, uma vez que foi mais freqüente em MTCs com c-KIT citoplasmático. A relação entre a expressão de IGF-1, SCF, c-KIT e m-TOR pode estar associada à integralização de suas vias de ação. A expressão de IGF-1 está associada à MTCs em cães de porte grande.Cutaneous mast cell tumor (MCT is one of the most common neoplasms in the skin of dogs and express variable biological behavior. Among the MTC aspects studied, histological classification, proliferative index and protein expression of c-KIT show the most defined connection with the tumor prognostic. The aim of this study was to evaluate the

  8. Qual a relevância dos sinais e sintomas no prognóstico de pacientes com hérnia de disco lombar? ¿Cuál la relevancia de los signos y síntomas en el pronóstico de pacientes con hernia de disco lumbar? What is the relevance of signs and symptoms in the prognosis of patients with lumbar disc herniation?

    Directory of Open Access Journals (Sweden)

    Asdrubal Falavigna

    2010-06-01

    Full Text Available INTRODUÇÃO: a hérnia de disco lombar (HDL é uma patologia prevalente na atualidade, que acarreta limitações físicas, psiquícas e sociais ao paciente. Os sinais e sintomas mais frequentes são lombociatalgia, distúrbios motores e sensitivos e sinal de Lasègue. Nos pacientes com HDL refrátarios ao tratamento clínico, microdiscectomia é o procedimento padrão para a melhora dos sintomas. OBJETIVOS: estudar a relevância prognóstica dos sinais e sintomas nos pacientes com HDL refratários ao tratamento clínico. MÉTODOS: foram pesquisados, nas principais bases de dados biomédicas, os artigos que estudaram a percentagem de melhora e o valor prognóstico dos sinais e sintomas pré-operatórios dos pacientes com HDL. Os sinais e os sintomas avaliados foram dor lombar, dor na perna, distúrbios motores e sensitivos e sinal de Lasègue. CONCLUSÃO: o índice de sucesso da cirurgia dos pacientes com HDL refratários ao tratamento clínico correlaciona-se com a ausência de lombalgia, a presença de ciatalgia com tempo de evolução de até 6 meses, o déficit sensitivo presente de forma isolada ou associado ao déficit motor e a presença de sinal de Lasègue positivo no período pré-operatório.INTRODUCCIÓN: la hernia de disco lumbar (HDL es una patología prevalente en la actualidad, que implica limitaciones físicas, psíquicas y sociales al paciente. Los signos y síntomas más frecuentes son la lumbociatalgia, los disturbios motores y sensitivos y el signo de Lasègue. En los pacientes con HDL refractarios al tratamiento clínico, la microdiscectomía es el procedimiento estándar para mejoría de los síntomas. OBJETIVOS: estudiar la relevancia del pronóstico de los signos y síntomas en los pacientes con HDL refractarios al tratamiento clínico. MÉTODOS: se realizó una investigación, en las principales bases de datos biomédicos, de los artículos que estudiaron el porcentaje de mejoría y el valor pronóstico de los signos y

  9. Spacetime information

    International Nuclear Information System (INIS)

    Hartle, J.B.

    1995-01-01

    In usual quantum theory, the information available about a quantum system is defined in terms of the density matrix describing it on a spacelike surface. This definition must be generalized for extensions of quantum theory which neither require, nor always permit, a notion of state on a spacelike surface. In particular, it must be generalized for the generalized quantum theories appropriate when spacetime geometry fluctuates quantum mechanically or when geometry is fixed but not foliable by spacelike surfaces. This paper introduces a four-dimensional notion of the information available about a quantum system's boundary conditions in the various sets of decohering, coarse-grained histories it may display. This spacetime notion of information coincides with the familiar one when quantum theory is formulable in terms of states on spacelike surfaces but generalizes this notion when it cannot be so formulated. The idea of spacetime information is applied in several contexts: When spacetime geometry is fixed the information available through alternatives restricted to a fixed spacetime region is defined. The information available through histories of alternatives of general operators is compared to that obtained from the more limited coarse grainings of sum-over-histories quantum mechanics that refer only to coordinates. The definition of information is considered in generalized quantum theories. We consider as specific examples time-neutral quantum mechanics with initial and final conditions, quantum theories with nonunitary evolution, and the generalized quantum frameworks appropriate for quantum spacetime. In such theories complete information about a quantum system is not necessarily available on any spacelike surface but must be searched for throughout spacetime. The information loss commonly associated with the ''evolution of pure states into mixed states'' in black hole evaporation is thus not in conflict with the principles of generalized quantum mechanics

  10. Exchanging information

    International Nuclear Information System (INIS)

    1971-01-01

    The Agency has a statutory mandate to foster 'the exchange of scientific and technical information on the peaceful uses of atomic energy'. The prime responsibility for this work within the Agency lies with the Division of Scientific and Technical Information, a part of the Department of Technical Operations. The Division accomplishes its task by holding conferences and symposia (Scientific Conferences Section), through the Agency Library, by publishing scientific journals, and through the International Nuclear Information System (INIS). The Computer Section of the Division, which offers services to the Agency as a whole, provides resources for the automation of data storage and retrieval. (author)

  11. Information evaluation

    CERN Document Server

    Capet, Philippe

    2014-01-01

    During the reception of a piece of information, we are never passive. Depending on its origin and content, from our personal beliefs and convictions, we bestow upon this piece of information, spontaneously or after reflection, a certain amount of confidence. Too much confidence shows a degree of naivety, whereas an absolute lack of it condemns us as being paranoid. These two attitudes are symmetrically detrimental, not only to the proper perception of this information but also to its use. Beyond these two extremes, each person generally adopts an intermediate position when faced with the recep

  12. How Informed Are Informal Educators?

    Science.gov (United States)

    Lederman, Norman G.; Niess, Margaret L.

    1998-01-01

    Explores current reforms in both mathematics and science education that emphasize the importance of learning in informal settings. Suggests that informal education must include planned and purposeful attempts to facilitate students' understanding of mathematics and science in community settings other than the local school. (Author/CCM)

  13. Informed consent: information or knowledge?

    Science.gov (United States)

    Berger, Ken

    2003-01-01

    A fiduciary relationship should be nurtured between patient and physician. This requires effective communication throughout all aspects of care - especially pertaining to treatment decisions. In the context of illness as experienced by the patient a unique set of circumstances is presented. However, communication in an illness context is fraught with problems. The patient is vulnerable and the situation may be overwhelming. Voluminous amounts of information are available to patients from a host of health care providers, family members, support groups, advocacy centers, books, journals, and the internet. Often conflicting and confusion, frequently complex, this information may be of greater burden than benefit. Some information is of high validity and reliability while other information is of dubious reliability. The emotional freight of bad news may further inhibit understanding. An overload of information may pose an obstacle in decision-making. To facilitate the transformation of information into knowledge, the health care provider must act on some occasions as a filter, on other occasions as a conduit, and on still other occasions simply as a reservoir. The evolution of patient rights to receive or refuse treatment, the right to know or not to know calls for a change in processing of overwhelming information in our modem era. In this paper we will discuss the difference between information and knowledge. How can health care providers ensure they have given their patients all necessary and sufficient information to make an autonomous decision? How can they facilitate the transformation of information into knowledge? The effect of knowledge to consent allows a more focused, relevant and modern approach to choice in health care.

  14. Information Managerx

    African Journals Online (AJOL)

    USER

    1996-10-01

    Oct 1, 1996 ... locate and access information from current awareness sources such as newspapers and radio. Legislators (35%) ... law-making and supervision for a viable democracy .... from a parliamentary library is a major concern for.

  15. Position Information

    Data.gov (United States)

    Social Security Administration — The Position Information Data Asset provides the ability to search for active SSA position descriptions using various search criteria. An individual may search by PD...

  16. INFORMATION MANAGERx

    African Journals Online (AJOL)

    USER

    information but also quickly access and retrieve large volume of ... created their management becomes a challenge for most institutions .... continuous upgrade of operating system, .... Tammro, A.M (2006) the Digital Library Users: Case.

  17. Supporting Information

    Data.gov (United States)

    U.S. Environmental Protection Agency — This is the supporting information for the journal article. This dataset is associated with the following publication: Rankin, K., S. Mabury, T. Jenkins, and J....

  18. Supplemental information

    Data.gov (United States)

    U.S. Environmental Protection Agency — Supplemental information showing results of inter-comparison between C-PORT, AERMOD and R-LINE dispersion algorithms. This dataset is associated with the following...

  19. Information Literacy

    African Journals Online (AJOL)

    ian

    Institutions are consequently introducing information literacy programmes in their curricula in a bid to ..... Brazil, Chile and Mexico (Lau 2007:31). Lau (2007) reported that these initiatives rarely involve IL inclusion in curricula and are scattered ...

  20. Information Managerx

    African Journals Online (AJOL)

    USER

    Communication technologies (ICTs) to Library Operations and Routines in Selected Nigerian Federal University ... should use Open-source library information management software and DSpace content management ..... Marketing of library.

  1. UBS INFORMATION

    CERN Document Server

    UBS

    2002-01-01

    As a supplement to the information published on 27.05.2002, we inform you that the works foreseen in the building 504 will begin July 1st. The alterations become necessary force us to suspend the contomat service for a duration of one month. From July 1st the services of counter will be offered in the building 500. We ask you to excuse us for this interruption and thank you for your understanding. Your UBS

  2. Information circulars

    International Nuclear Information System (INIS)

    1987-06-01

    The document summarizes the information circulars published by the IAEA for the purpose of bringing matters of general interest to the attention of all Members of the Agency. In the main body of the document only those documents which are regarded as likely to be of current interest are listed. A complete numerical list of information circulars with their titles is reproduced in the Annex

  3. Information engineering

    Energy Technology Data Exchange (ETDEWEB)

    Hunt, D.N.

    1997-02-01

    The Information Engineering thrust area develops information technology to support the programmatic needs of Lawrence Livermore National Laboratory`s Engineering Directorate. Progress in five programmatic areas are described in separate reports contained herein. These are entitled Three-dimensional Object Creation, Manipulation, and Transport, Zephyr:A Secure Internet-Based Process to Streamline Engineering Procurements, Subcarrier Multiplexing: Optical Network Demonstrations, Parallel Optical Interconnect Technology Demonstration, and Intelligent Automation Architecture.

  4. Quantum information

    International Nuclear Information System (INIS)

    Kilin, Sergei Ya

    1999-01-01

    A new research direction known as quantum information is a multidisciplinary subject which involves quantum mechanics, optics, information theory, programming, discrete mathematics, laser physics and spectroscopy, and depends heavily on contributions from such areas as quantum computing, quantum teleportation and quantum cryptography, decoherence studies, and single-molecule and impurity spectroscopy. Some new results achieved in this rapidly growing field are discussed. (reviews of topical problems)

  5. Quantum information

    Energy Technology Data Exchange (ETDEWEB)

    Kilin, Sergei Ya [B.I. Stepanov Institute of Physics, National Academy of Sciences of Belarus, Minsk (Belarus)

    1999-05-31

    A new research direction known as quantum information is a multidisciplinary subject which involves quantum mechanics, optics, information theory, programming, discrete mathematics, laser physics and spectroscopy, and depends heavily on contributions from such areas as quantum computing, quantum teleportation and quantum cryptography, decoherence studies, and single-molecule and impurity spectroscopy. Some new results achieved in this rapidly growing field are discussed. (reviews of topical problems)

  6. Information Literacy

    OpenAIRE

    Basili, Carla

    2015-01-01

    Information literacy is a concept which is well established in theory while in practice it is only slowly breaking ground in accordance with the understanding of its significance and the possibilities of its realisation. Based on fundamental works, the characteristics of information literacy, its cognitive foundations and significance for individuals as well as for society, are argumented in the article. The analyzed content of this concept is connected with the content of a librarian’s knowl...

  7. Information Presentation

    Science.gov (United States)

    Holden, K.L.; Boyer, J.L.; Sandor, A.; Thompson, S.G.; McCann, R.S.; Begault, D.R.; Adelstein, B.D.; Beutter, B.R.; Stone, L.S.

    2009-01-01

    The goal of the Information Presentation Directed Research Project (DRP) is to address design questions related to the presentation of information to the crew. The major areas of work, or subtasks, within this DRP are: 1) Displays, 2) Controls, 3) Electronic Procedures and Fault Management, and 4) Human Performance Modeling. This DRP is a collaborative effort between researchers at Johnson Space Center and Ames Research Center.

  8. Informal Innovation

    DEFF Research Database (Denmark)

    Hartmann, Mia Rosa Koss; Hartmann, Rasmus Koss

    Informal innovation, defined as the development and putting-into-use of novel solutions by non-R&D employees without prior formal approval from or subsequent revealing to superiors, has been recurrently observed in organizational research. But even as it is increasingly recognized that R&D is not......Informal innovation, defined as the development and putting-into-use of novel solutions by non-R&D employees without prior formal approval from or subsequent revealing to superiors, has been recurrently observed in organizational research. But even as it is increasingly recognized that R......&D is not the only plausible source of innovation inside organizations, informal innovation has yet to be systematically explored or theorized. We propose a theory of informal innovation based on analyses of prior literature and mixed-method, multi-site studies of innovation at the working level of two extreme......-case organizations. We propose that informal innovation occurs as 1) employees personally experience problems that they believe are not recognized or prioritized by superiors; 2) some employees are able to develop solutions, essentially at no cost; 3) innovators face no benefits from revealing to superiors, but can...

  9. When Information Improves Information Security

    Science.gov (United States)

    Grossklags, Jens; Johnson, Benjamin; Christin, Nicolas

    This paper presents a formal, quantitative evaluation of the impact of bounded-rational security decision-making subject to limited information and externalities. We investigate a mixed economy of an individual rational expert and several naïve near-sighted agents. We further model three canonical types of negative externalities (weakest-link, best shot and total effort), and study the impact of two information regimes on the threat level agents are facing.

  10. Information barriers

    International Nuclear Information System (INIS)

    Fuller, J.L.; Wolford, J.

    2001-01-01

    Full text: An information barrier (IB) consists of procedures and technology that prevent the release of sensitive information during a joint inspection of a sensitive nuclear item, and provides confidence that the measurement system into which it has been integrated functions exactly as designed and constructed. Work in the U.S. on radiation detection system information barriers dates back at least to 1990, even though the terminology is more recent. In January 1999 the Joint DoD-DOE Information Barrier Working Group was formed in the United States to help coordinate technical efforts related to information barrier R and D. This paper presents an overview of the efforts of this group, by its Chairs, as well as recommendations for further information barrier R and D. Progress on the demonstration of monitoring systems containing IBs is also provided. From the U.S. perspective, the basic, top-level functional requirements for the information barrier portion of an integrated radiation signature-information barrier inspection system are twofold: The host must be assured that his classified information is protected from disclosure to the inspecting party; and The inspecting party must be confident that the integrated inspection system measures, processes, and presents the radiation-signature-based measurement conclusion in an accurate and reproducible manner. It is the position of the United States that in the absence of any agreement to share classified nuclear weapons design information in the conduct of an inspection regime, the requirement to protect host country classified warhead design information is paramount and admits no tradeoff versus the confidence provided to the inspecting party in the accuracy and reproducibility of the measurements. The U.S. has reached an internal consensus on several critical design elements that define a general standard for radiation signature information barrier design. These criteria have stood the test of time under intense

  11. Rhinosinusitis in autologous and allogeneic bone marrow transplantation: a retrospective study on the performance of imaging studies on severity and prognostic evaluation Rinossinusite em transplante de células-tronco hematopoéticas autólogo e alogênico: um estudo retrospectivo sobre o desempenho de estudos de imagem na avaliação de severidade e prognóstico

    Directory of Open Access Journals (Sweden)

    Leo Sekine

    2010-02-01

    Full Text Available The objective of this work was to evaluate the diagnostic and prognostic performance of a traditional imaging staging system for rhinosinusitis in the bone marrow transplantation (BMT scenario. A retrospective cohort study was carried out at a bone marrow transplantation referral center involving subjects who underwent allogeneic or autologous BMT from September 1st 2005 to September 31st 2007 and later evolved with rhinosinusitis during the BMT inpatient period. Patients who had a previous history of sinusal disease or otolaryngologic surgery were excluded from the study. Data concerning mortality, the treatment of rhinosinusitis and BMT outcomes were extracted from medical files. The collected parameters were compared to the Lund-Mackay tomographic staging system score which was calculated based on available tomography films of each patient. A total of 85 BMT were performed and 23 allogeneic and 14 autologous (43.5% BMT patients evolved with rhinosinusitis during transplantation. A significant association with LMS was found for the absolute neutrophil count (ANC, with a higher ANC (>500/mm3 correlating with a higher LMS (Mean LMS for lower ANC 6.08 and higher ANC 9.71 points, pO objetivo deste trabalho foi avaliar o desempenho diagnóstico e prognóstico de um escore de estadiamento de rinossinusite (RS por tomografia em pacientes submetidos a transplante de medula óssea (TMO. Realizou-se um estudo de coorte retrospectivo de pacientes submetidos a transplante de medula óssea (autólogo e alogênico de 1º de setembro de 2005 a 31 de setembro de 2007 que desenvolveram RS durante o período de internação do transplante. Pacientes com história prévia de doença sinusal ou cirurgia otorrinolaringológica foram excluídos do estudo. Dados relacionados à mortalidade, resolução da RS e desfechos do TMO foram extraídos do prontuário médico. Os parâmetros coletados foram correlacionados com o escore de estadiamento de Lund-Mackay (ELM, que

  12. Evolução da função renal na fase aguda do infarto do miocárdio como fator prognóstico de eventos na fase intra-hospitalar e em um ano de seguimento Renal function outcome in acute myocardial infarction as a prognostic factor of in-hospital events and at one-year follow-up

    Directory of Open Access Journals (Sweden)

    Eduardo Pimenta

    2006-03-01

    Full Text Available OBJETIVO: Analisar o papel da disfunção renal na internação ou durante a evolução nos pacientes com infarto agudo do miocárdio (IAM. MÉTODOS: Foram avaliados 274 pacientes com IAM, entre janeiro de 2000 e dezembro de 2001. A função renal foi monitorada com a dosagem de creatinina (Cr na internação e o valor pico durante a hospitalização. O clearance de creatinina (ClCr foi calculado pela fórmula de Cockcroft & Gault. Foi avaliada a morbidade e mortalidade intra-hospitalar e após um ano do evento. RESULTADOS: A média de idade foi 62,2 ± 13,5 anos e 73% eram do sexo masculino. A função renal esteve mais reduzida nos homens, em pacientes com hipertensão arterial sistêmica e cirurgia de revascularização prévia. A análise multivariada revelou aumento da mortalidade intra-hospitalar relacionada com a elevação nos níveis pico de Cr (OR:1,18 95% IC:1,18-2,77 p = 0,006, com o decréscimo no ClCr inicial (OR:0,96 95% IC:0,93-0,99 p = 0,025 e no ClCr pico (OR:0,96 95% IC:0,92-0,99 p = 0,023. A diferença percentual entre o ClCr inicial e o menor ClCr atingido também indicou maior mortalidade (OR:1,04 95% IC:1,00-1,07 p = 0,033. A piora da função renal não alterou a morbidade e mortalidade em um ano. CONCLUSÃO: Disfunção renal na internação, e sua deterioração durante a hospitalização, mostrou ser um importante marcador prognóstico de pior evolução imediata.OBJECTIVE: To analyze the role of renal dysfunction at admission or during hospitalization in patients with acute myocardial infarction (AMI. METHODS: Two hundred and seventy-four patients with AMI were assessed between January 2000 and December 2001. Renal function was monitored by serum creatinine (Cr measurement at admission and peak level during hospitalization. Creatinine clearance (CrCl was estimated by the Cockcroft-Gault formula. In-hospital and one-year morbidity and mortality were evaluated. RESULTS: Mean age of the population studied was 62.2 ± 13

  13. Information Service.

    Science.gov (United States)

    Scofield, James

    Newspaper librarians discussed the public use of their newspapers' libraries. Policies run the gamut from well-staffed public information services, within or outside the newspaper library, to no service at all to those outside the staff of the paper. Problems of dealing with tax and law enforcement agencies were covered, as well as cooperative…

  14. Informed policies

    International Development Research Centre (IDRC) Digital Library (Canada)

    INTERNATIONAL DEVELOPMENT RESEARCH CENTRE. Informed ... more evidence-based policy on social ... Community involvement is key to the success of CBMS in reducing poverty. IDRC ... nationwide network of “telecentres” that ... and holidays for young people to use for ... National Conference on Youth led to the.

  15. Informational precaution

    NARCIS (Netherlands)

    Pieters, Wolter; Mainzer, K.

    2010-01-01

    In environmental ethics, the precautionary principle states that parties should refrain from actions in the face of scientific uncertainties about serious or irreversible harm to public health or the environment. A similar principle is lacking when judging effects of information technology. Such a

  16. Information Parallax

    NARCIS (Netherlands)

    Grootjen, F.A.; Weide, Th.P. van der; Sugumaran, V.

    2007-01-01

    To effectively use and exchange information among AI systems, a formal specification of the representation of their domain of discourse - called an ontology - is indispensable. In this chapter we introduce a special kind of knowledge representation based on a dual view on the universe of discourse

  17. Information Security

    NARCIS (Netherlands)

    Hartel, Pieter H.; Suryana Herman, Nanna; Leukfeldt, E.R.; Stol, W.Ph.

    2012-01-01

    Information security is all about the protection of digital assets, such as digital content, personal health records, state secrets etc. These assets can be handled by a party who is authorised to access and control the asset or a party who is not authorised to do so. Authorisation determines who is

  18. INFORMATION MANAGERx

    African Journals Online (AJOL)

    USER

    Four research questions were posed in order to assess the Mac Arthur ... The research adopted survey method using questionnaire as instrument for data ... serial resources in these university libraries were inadequate before the ... and societal development has made the demand for ..... Information Management in Nigeria.

  19. Information circulars

    International Nuclear Information System (INIS)

    1989-04-01

    The document summarizes the Information Circulars published by the IAEA under the symbol INFCIRC/ for the purpose of bringing matters of general interest to the attention of all Members of the Agency. A complete list of INFCIRCs in numerical order with their titles is given in the Annex

  20. Information Circulars

    International Nuclear Information System (INIS)

    1966-01-01

    Information circulars are published from time to time under the symbol INFCIRC/. . . . for the purpose of bringing matters of general interest to the attention of all Members of the Agency. A list of the circulars that were current or on the press on 15 May 1966 is given, followed by an index to their subject matter.

  1. Information Circulars

    International Nuclear Information System (INIS)

    1965-01-01

    Information circulars are published from time to time under the symbol INFCIRC/. for the purpose of bringing matters of general interest to the attention of all Members of the Agency. A list of the circulars that were current on 31 December 1964 is given, followed by an index to their subject matter.

  2. Supplementary information

    Indian Academy of Sciences (India)

    Supplementary information. Flexible synthesis of isomeric pyranoindolones and evaluation of cytotoxicity towards HeLa cells. J C JEYAVEERANa, CHANDRASEKAR PRAVEEN*,b, Y ARUNc, A A M PRINCEa and P. T PERUMALc. aDepartment of Chemistry, Ramakrishna Mission Vivekananda College, Mylapore, Chennai.

  3. Information week...

    CERN Multimedia

    Staff Association

    2007-01-01

    Here we are at the end of a series of public information meetings held in the Departments. We thank all those who came to find out about the subjects presented and to exchange ideas and opinions. All the positive feedback we have received shows how much you appreciate these meetings. And well, so do we!

  4. Information Circulars

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1966-06-10

    Information circulars are published from time to time under the symbol INFCIRC/. . . . for the purpose of bringing matters of general interest to the attention of all Members of the Agency. A list of the circulars that were current or on the press on 15 May 1966 is given, followed by an index to their subject matter.

  5. Information Circulars

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1965-01-18

    Information circulars are published from time to time under the symbol INFCIRC/. for the purpose of bringing matters of general interest to the attention of all Members of the Agency. A list of the circulars that were current on 31 December 1964 is given, followed by an index to their subject matter.

  6. Information Ecology

    DEFF Research Database (Denmark)

    Christiansen, Ellen Tove

    2006-01-01

    in the 1960ties, and chosen here because it integrates cultural and psychological trajectories in a theory of living settings. The pedagogical-didactical paradigm comprises three distinct information ecologies, named after their intended outcome: the problem-setting, the exploration-setting, and the fit...

  7. Information geometry

    CERN Document Server

    Ay, Nihat; Lê, Hông Vân; Schwachhöfer, Lorenz

    2017-01-01

    The book provides a comprehensive introduction and a novel mathematical foundation of the field of information geometry with complete proofs and detailed background material on measure theory, Riemannian geometry and Banach space theory. Parametrised measure models are defined as fundamental geometric objects, which can be both finite or infinite dimensional. Based on these models, canonical tensor fields are introduced and further studied, including the Fisher metric and the Amari-Chentsov tensor, and embeddings of statistical manifolds are investigated. This novel foundation then leads to application highlights, such as generalizations and extensions of the classical uniqueness result of Chentsov or the Cramér-Rao inequality. Additionally, several new application fields of information geometry are highlighted, for instance hierarchical and graphical models, complexity theory, population genetics, or Markov Chain Monte Carlo. The book will be of interest to mathematicians who are interested in geometry, inf...

  8. Informed consent

    International Nuclear Information System (INIS)

    Bundy, A.L.

    1988-01-01

    Numerous articles on informed consent have appeared in medical and legal journals over the past few years. Many of these have been in the radiological literature. This chapter presents an overview of the legal principles behind this controversial topic. Recent articles are reviewed and specific suggestions are made where applicable. The doctrine of informed consent is both a product of and the basis for the physician-patient relationship. Their communications to each other establish the relationship, but once established, heightened degrees of expectations on the patient's part have dictated the need for a more sophisticated level of communication. Since patients and physicians often expect different things of each other, it is imperative that the relationship leads to effective and respectful conversation

  9. Information Circulars

    International Nuclear Information System (INIS)

    1969-01-01

    Information circulars are published from time to time under the symbol INFCIRC/. . . . for the purpose of bringing matters of general interest to the attention of all Members of the Agency. A list of the circulars which were of current interest on 15 January 1969 is given below, followed by an index to their subject matter. Other circulars can be traced by reference to earlier issues of the present document.

  10. Information Engineering.

    Science.gov (United States)

    1982-01-01

    34 continuously over time " through a division of labor and responsibility " integrated by INFORMATION-BASED decision process * in an environment of stress...responsibilities for learning in a particular field. This division of labor is especially true for staff members who must develop expertise in particular...likely founa a commano clima e with: - Multiple layering - Sub optimization Policy of no surprises - Lip service to feedback - Over centralization and non

  11. Information Circulars

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1969-01-24

    Information circulars are published from time to time under the symbol INFCIRC/. . . . for the purpose of bringing matters of general interest to the attention of all Members of the Agency. A list of the circulars which were of current interest on 15 January 1969 is given below, followed by an index to their subject matter. Other circulars can be traced by reference to earlier issues of the present document.

  12. Medizinbibliotheken: Information

    Directory of Open Access Journals (Sweden)

    Bauer, Bruno

    2014-12-01

    Full Text Available [english] The focus of the current issue 3/2014 of GMS Medizin – Bibliothek – Information is the annual conference 2014 of the German Medical Libraries Association in Mannheim. The motto of the conference was “Medical libraries: Information”. The authors in this issue are Michaele Adam (Bibliometrics 2.0 – Altmetrics in Medicine, Bruno Bauer (Open access cooperation in Austria: Open Access Network Austria and Austria – recent developments since 2012, Fabian Gail & Ulrich Korwitz (Market and strategy – results of the ZB MED market study, Sabine Gehrlein (Library goes Anatomy: Anatomical teaching media at Heidelberg University Library, Kaja Scheliga (Opening science: New publication forms in science, Ulrike Ostrzinski (The four types of social media user in the academic and research community. Results of a nationwide study, Sandra Pfob & Alena Ittner (First aid for library use on PC: webinars increase library visits, reach everyone, save costs, Simone Waldboth (Integration of e-learning in the lecture “Information Literacy” at the Provincial College for Health-Care Professions Claudiana, Maike Piegler (The pick up box of the library of the Hamburg medical association – a way to bring scientific information to medical specialists and Christoph Wehrmüller & Heidrun Janka (Medical : Information – Annual meeting 2014 of the German MLA, September 22 to 24 in Mannheim.Furthermore this focus issue features articles from Bruno Bauer (: transformation strategies for subscription-based journaleport on the 8 Open Access Days at Cologne, September 8–9 2014, Eike Hentschel (German MLA News; Pioneer projects in medical libraries 2014: Introduction of the winners; Pioneer projects in medical libraries 2015 – Announcement and Franz J. Kühnen (Klaus Gerber 1934–2014.

  13. Information Technology

    Science.gov (United States)

    2003-01-01

    2003. http://cse.org/informed/issues_template.php/1250.htm [60] World Bank. E- Government , www1.worldbank.org/publicsector/ egov /definition.htm [61...Office of Management and Budget, E-Gov Related Legislation Overview. www.whitehouse.gov/omb/ egov /about_leg.htm [62] E- Government Act, December 17...s, the IT industry contributed 30% to U.S. GDP growth. Additionally, ev military service transformation relies heavily on IT. An IT advantage is

  14. Information services and information processing

    Science.gov (United States)

    1975-01-01

    Attempts made to design and extend space system capabilities are reported. Special attention was given to establishing user needs for information or services which might be provided by space systems. Data given do not attempt to detail scientific, technical, or economic bases for the needs expressed by the users.

  15. Teaching Information Skills: Recording Information.

    Science.gov (United States)

    Pappas, Marjorie L.

    2002-01-01

    Discusses how to teach students in primary and intermediate grades to record and organize information. Highlights include developing a research question; collaborative planning between teachers and library media specialists; consistency of data entry; and an example of a unit on animal migration based on an appropriate Web site. (LRW)

  16. Informal learning.

    Science.gov (United States)

    Callanan, Maureen; Cervantes, Christi; Loomis, Molly

    2011-11-01

    We consider research and theory relevant to the notion of informal learning. Beginning with historical and definitional issues, we argue that learning happens not just in schools or in school-aged children. Many theorists have contrasted informal learning with formal learning. Moving beyond this dichotomy, and away from a focus on where learning occurs, we discuss five dimensions of informal learning that are drawn from the literature: (1) non-didactive, (2) highly socially collaborative, (3) embedded in meaningful activity, (4) initiated by learner's interest or choice, and (5) removed from external assessment. We consider these dimensions in the context of four sample domains: learning a first language, learning about the mind and emotions within families and communities, learning about science in family conversations and museum settings, and workplace learning. Finally, we conclude by considering convergences and divergences across the different literatures and suggesting areas for future research. WIREs Cogni Sci 2011 2 646-655 DOI: 10.1002/wcs.143 For further resources related to this article, please visit the WIREs website. Copyright © 2011 John Wiley & Sons, Ltd.

  17. Information resources

    Science.gov (United States)

    Friend, Milton; Franson, J. Christian; Friend, Milton; Gibbs, Samantha E.J.; Wild, Margaret A.

    2015-10-19

    During recent decades, natural resources agency personnel and others involved with the management and stewardship of wildlife have experienced an increasing need to access information and obtain technical assistance for addressing a diverse array of wildlife disease issues. This Chapter provides a broad overview of selected sources for obtaining supplemental information and technical assistance for addressing wildlife disease issues in North America. Specifically, examples of existing major wildlife disease programs focusing on free-ranging wildlife populations are highlighted; training opportunities for enhancing within-agency wildlife disease response are identified; a selected reading list of wildlife disease references is provided; and selected Web sites providing timely information on wildlife disease are highlighted. No attempt is made to detail all the North American programs and capabilities that address disease in free-ranging wildlife populations. Instead, this Chapter is focused on enhancing awareness of the types of capabilities that exist as potential sources for assistance and collaboration between wildlife conservation agency personnel and others in addressing wildlife disease issues.

  18. Information Circulars

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1973-09-10

    Information circulars are published from time to time under the symbol INFCIRC/.. for the purpose of bringing matters of general interest to the attention of all Members of the Agency. A subject index to the circulars is presented overleaf. It covers all those published in the last five years (that is, since the beginning of 1968 and ending with INFCIRC/192), as well as others which, for one reason or another, are still considered to be of current rather than merely historical interest. Such circulars can be traced by reference to the indexes that were included in earlier revisions of the present document.

  19. Information Security

    OpenAIRE

    2005-01-01

    Information security is all about the protection of digital assets, such as digital content, personal health records, state secrets etc. These assets can be handled by a party who is authorised to access and control the asset or a party who is not authorised to do so. Authorisation determines who is trusted to actually handle an asset. Two concepts complement authorisation. Authentication deter-mines who makes a request to handle an asset. To decide who is authorised, a system needs to au-the...

  20. Information Circulars

    International Nuclear Information System (INIS)

    1973-01-01

    Information circulars are published from time to time under the symbol INFCIRC/.. for the purpose of bringing matters of general interest to the attention of all Members of the Agency. A subject index to the circulars is presented overleaf. It covers all those published in the last five years (that is, since the beginning of 1968 and ending with INFCIRC/192), as well as others which, for one reason or another, are still considered to be of current rather than merely historical interest. Such circulars can be traced by reference to the indexes that were included in earlier revisions of the present document.

  1. Quantum information

    International Nuclear Information System (INIS)

    Rodgers, P.

    1998-01-01

    There is more to information than a string of ones and zeroes the ability of ''quantum bits'' to be in two states at the same time could revolutionize information technology. In the mid-1930s two influential but seemingly unrelated papers were published. In 1935 Einstein, Podolsky and Rosen proposed the famous EPR paradox that has come to symbolize the mysteries of quantum mechanics. Two years later, Alan Turing introduced the universal Turing machine in an enigmatically titled paper, On computable numbers, and laid the foundations of the computer industry one of the biggest industries in the world today. Although quantum physics is essential to understand the operation of transistors and other solid-state devices in computers, computation itself has remained a resolutely classical process. Indeed it seems only natural that computation and quantum theory should be kept as far apart as possible surely the uncertainty associated with quantum theory is anathema to the reliability expected from computers? Wrong. In 1985 David Deutsch introduced the universal quantum computer and showed that quantum theory can actually allow computers to do more rather than less. The ability of particles to be in a superposition of more than one quantum state naturally introduces a form of parallelism that can, in principle, perform some traditional computing tasks faster than is possible with classical computers. Moreover, quantum computers are capable of other tasks that are not conceivable with their classical counterparts. Similar breakthroughs in cryptography and communication followed. (author)

  2. Quantum information

    Energy Technology Data Exchange (ETDEWEB)

    Rodgers, P

    1998-03-01

    There is more to information than a string of ones and zeroes the ability of ''quantum bits'' to be in two states at the same time could revolutionize information technology. In the mid-1930s two influential but seemingly unrelated papers were published. In 1935 Einstein, Podolsky and Rosen proposed the famous EPR paradox that has come to symbolize the mysteries of quantum mechanics. Two years later, Alan Turing introduced the universal Turing machine in an enigmatically titled paper, On computable numbers, and laid the foundations of the computer industry one of the biggest industries in the world today. Although quantum physics is essential to understand the operation of transistors and other solid-state devices in computers, computation itself has remained a resolutely classical process. Indeed it seems only natural that computation and quantum theory should be kept as far apart as possible surely the uncertainty associated with quantum theory is anathema to the reliability expected from computers? Wrong. In 1985 David Deutsch introduced the universal quantum computer and showed that quantum theory can actually allow computers to do more rather than less. The ability of particles to be in a superposition of more than one quantum state naturally introduces a form of parallelism that can, in principle, perform some traditional computing tasks faster than is possible with classical computers. Moreover, quantum computers are capable of other tasks that are not conceivable with their classical counterparts. Similar breakthroughs in cryptography and communication followed. (author)

  3. Quantum information

    Energy Technology Data Exchange (ETDEWEB)

    Rodgers, P

    1998-03-01

    There is more to information than a string of ones and zeroes the ability of ''quantum bits'' to be in two states at the same time could revolutionize information technology. In the mid-1930s two influential but seemingly unrelated papers were published. In 1935 Einstein, Podolsky and Rosen proposed the famous EPR paradox that has come to symbolize the mysteries of quantum mechanics. Two years later, Alan Turing introduced the universal Turing machine in an enigmatically titled paper, On computable numbers, and laid the foundations of the computer industry one of the biggest industries in the world today. Although quantum physics is essential to understand the operation of transistors and other solid-state devices in computers, computation itself has remained a resolutely classical process. Indeed it seems only natural that computation and quantum theory should be kept as far apart as possible surely the uncertainty associated with quantum theory is anathema to the reliability expected from computers? Wrong. In 1985 David Deutsch introduced the universal quantum computer and showed that quantum theory can actually allow computers to do more rather than less. The ability of particles to be in a superposition of more than one quantum state naturally introduces a form of parallelism that can, in principle, perform some traditional computing tasks faster than is possible with classical computers. Moreover, quantum computers are capable of other tasks that are not conceivable with their classical counterparts. Similar breakthroughs in cryptography and communication followed. (author)

  4. Information management - Assessing the demand for information

    Science.gov (United States)

    Rogers, William H.

    1991-01-01

    Information demand is defined in terms of both information content (what information) and form (when, how, and where it is needed). Providing the information richness required for flight crews to be informed without overwhelming their information processing capabilities will require a great deal of automated intelligence. It is seen that the essence of this intelligence is comprehending and capturing the demand for information.

  5. Information Impact: Journal of Information and Knowledge ...

    African Journals Online (AJOL)

    Information Impact: Journal of Information and Knowledge Management: Advanced Search. Journal Home > Information Impact: Journal of Information and Knowledge Management: Advanced Search. Log in or Register to get access to full text downloads.

  6. Information Impact: Journal of Information and Knowledge ...

    African Journals Online (AJOL)

    Information Impact: Journal of Information and Knowledge Management: Site Map. Journal Home > About the Journal > Information Impact: Journal of Information and Knowledge Management: Site Map. Log in or Register to get access to full text downloads.

  7. Beyond information retrieval: information discovery and multimedia information retrieval

    OpenAIRE

    Roberto Raieli

    2017-01-01

    The paper compares the current methodologies for search and discovery of information and information resources: terminological search and term-based language, own of information retrieval (IR); semantic search and information discovery, being developed mainly through the language of linked data; semiotic search and content-based language, experienced by multimedia information retrieval (MIR).MIR semiotic methodology is, then, detailed.

  8. Information Need and Information Seeking Behaviour

    OpenAIRE

    Nazan Özenç Uçak

    1997-01-01

    Information need is one of the cognitive needs of humankind. Information need causes information seeking behaviour and these concepts complement each other. Information need and information seeking behaviour are effected by many factors. It is necessary to know these factors in establishing the effective information centers and services.

  9. Information Need and Information Seeking Behaviour

    Directory of Open Access Journals (Sweden)

    Nazan Özenç Uçak

    1997-12-01

    Full Text Available Information need is one of the cognitive needs of humankind. Information need causes information seeking behaviour and these concepts complement each other. Information need and information seeking behaviour are effected by many factors. It is necessary to know these factors in establishing the effective information centers and services.

  10. Information and information flow an introduction

    CERN Document Server

    Bremer, Manuel

    2004-01-01

    This book is conceived as an introductory text into the theory of syntactic and semantic information, and information flow. Syntactic information theory is concerned with the information contained in the very fact that some signal has a non-random structure. Semantic information theory is concerned with the meaning or information content of messages and the like. The theory of information flow is concerned with deriving some piece of information from another. The main part will take us to situation semantics as a foundation of modern approaches in information theory. We give a brief overview o

  11. Information Impact | Journal of Information and Knowledge ...

    African Journals Online (AJOL)

    Information Impact | Journal of Information and Knowledge Management

    Information Impact | Journal of Information and Knowledge Management. 77 ... Libraries all over the world are applying information and communication ..... Bank Branch Performance, The International Journal on Advances in ICT for Emerging.

  12. Pacientes clínicos referenciados, mas não internados na Unidade de Terapia Intensiva: prevalência, características clínicas e prognóstico Referred medical patients not admitted to the Intensive Care Unit: prevalence, clinical characteristics and prognosis

    Directory of Open Access Journals (Sweden)

    José Rodolfo Rocco

    2006-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A evolução dos pacientes cuja internação é negada nos centros de terapia intensiva (CTI é pouco conhecida. Os objetivos deste estudo foram comparar as características dos pacientes internados com aqueles que não foram internados em CTI e identificar os fatores associados com o processo de triagem para a internação. MÉTODO: Foi realizado um estudo do tipo coorte prospectiva e observacional durante 26 meses. Os dados dos pacientes foram coletados através de um formulário padronizado para a solicitação de internação no CTI. Os desfechos de interesse do estudo foram a internação no CTI e a evolução hospitalar. RESULTADOS: Foram estudados 455 pacientes dos quais 254 (56% foram internados e 201 (44% não; a maioria destes, por falta de vagas (82%. Os pacientes não internados apresentaram maior letalidade (85% versus 61%; p 70 anos [4,0(2,4-6,5], cirrose hepática [3,7(1,8-7,5], e escala de coma de Glasgow BACKGROUND AND OBJECTIVES: Information on the outcomes of patients who were refused to the ICU is limited. The aims of this study were to compare the clinical characteristics of patients who were admitted with those of patients who were refused to the ICU and to identify clinical parameters associated with triage procedures. METHODS: Observational prospective cohort study. The following data were collected using a standard questionnaire: comorbidities, acute illness, vital status, laboratory data and APACHE II score. The end-points of interest were admission to the ICU and vital status at hospital discharge. RESULTS: A total of 455 patients were studied; 254 (56% were admitted and 201 (44% were not. The main reason for the refuse of admission was the lack of ICU beds (82%. Patients who were not admitted had a higher mortality (85% vs. 61%; p 70 years [4.0(2.4-6.5], hepatic cirrhosis [3.7(1.8-7.6], and Glasgow coma scale < 5 [3.6(1.9-6.9]. The variables associated with ICU admission were: mechanical

  13. Ergonomics and information technique

    International Nuclear Information System (INIS)

    Krueger, H.

    1985-01-01

    Ergonomics are an essential safety factor in controlling automated processes. It has to be taken into account in three stages: information presentation, information perception and information treatment

  14. Information in organisations: directions for information management

    Directory of Open Access Journals (Sweden)

    Joyce Kirk

    1999-01-01

    Full Text Available The work of managers in small and medium-sized enterprises is very information-intensive and the environment in which it is done is very information rich. But are managers able to exploit the wealth of information which surrounds them? And how can information be managed in organisations so that its potential for improving business performance and enhancing the competitiveness of these enterprises can be realised? Answers to these questions lie in clarifying the context of the practice of information management by exploring aspects of organisations and managerial work and in exploring the nature of information at the level of the organisation and the individual manager. From these answers it is possible to suggest some guidelines for managing the integration of business strategy and information, the adoption of a broadly-based definition of information and the development of information capabilities.

  15. Network Centric Information Structure - Crisis Information Management

    National Research Council Canada - National Science Library

    Aarholt, Eldar; Berg, Olav

    2004-01-01

    This paper presents a generic Network Centric Information Structure (NCIS) that can be used by civilian, military and public sectors, and that supports information handling applied to crises management and emergency response...

  16. Rethinking information handling: designing for information offload

    DEFF Research Database (Denmark)

    Hansen, Lone Koefoed; Pedersen, Peter Dalsgård; Eriksson, Eva

    2005-01-01

    This paper introduces information offload as a supplement way of responding to and designing for information. By presenting iFlush, a design concept aiming at providing the user with a possibility to offload information and then instantly dispose of it, the paper presents an approach towards desi...... designing for reflection and also serves as a critique towards information overload. Furthermore, the absence of reflection on the role played by HCI community in the constant augmenting of all spaces is addressed....

  17. Information Assurance Security in the Information Environment

    CERN Document Server

    Blyth, Andrew

    2006-01-01

    Intended for IT managers and assets protection professionals, this work aims to bridge the gap between information security, information systems security and information warfare. It covers topics such as the role of the corporate security officer; Corporate cybercrime; Electronic commerce and the global marketplace; Cryptography; and, more.

  18. Information Sensitive Consumers and Market Information.

    Science.gov (United States)

    Price, Linda L.; And Others

    1987-01-01

    Past research on consumer information has emphasized the effects of informed consumers of the provision of goods by sellers. This paper examines the effects of informed consumers on other consumers' product choices. These are demand-side effects. Directions for research are outlined. Author/CH)

  19. Information Impact: Journal of Information and Knowledge ...

    African Journals Online (AJOL)

    Information Impact: Journal of Information and Knowledge Management

    Information Impact: Journal of Information and Knowledge Management. 55. Adeola Esther Olutoki ... The main instruments used for data collection were research ... collections in the library and enhance academic performance. ... libraries; they contain the latest information on research findings which are of great importance.

  20. Information Skills for an Information Age?

    Science.gov (United States)

    Gawith, Gwen

    1986-01-01

    Although information skills are the most basic of skills, the tendency is to teach strategies related to educational projects, erroneously assuming that these "information skills" are applicable to everyday decision-making. Educated imaginations are needed for today's variety of lifelong creative information situations. (17 references)…

  1. Agricultural informational flow in informal communication networks ...

    African Journals Online (AJOL)

    Agricultural informational flow in informal communication networks of farmers in Ghana. ... should identify such farmers who can serve as intermediaries between actors to help disseminate information in rural communities. Keywords: key communicators, farmers, rural communities, social networks, extension agents ...

  2. Organising and presenting information.

    Science.gov (United States)

    Kankanady, Raghavendra; Wells, Marilyn

    2013-01-01

    Information management can be a daunting process for clinicians, health care providers and policy makers within the health care industry. This chapter discusses the importance of information classification and information architecture in the information economy and specific challenges faced within the health care industry. The healthcare sector has industry specific requirements for information management, standards and specifications for information presentation. Classification of information based on information criticality and the value in the health care industry is discussed in this paper. Presentation of information with reference to eHealth standards and specifications for healthcare information systems and their key requirements are also discussed, as are information architecture for eHealth implementation in Australia. This chapter also touches on information management and clinical governance since the importance of information governance is discussed by various researchers and how this is becoming of value to healthcare information management.

  3. Curso clínico e prognóstico do transtorno obsessivo-compulsivo

    Directory of Open Access Journals (Sweden)

    Miranda Mary A

    2001-01-01

    Full Text Available The long-term course and prognosis of obsessive-compulsive disorder (OCD is insufficiently known. To identify predictors of OCD course, follow-up studies of patients with OCD were reviewed and their findings summarized. According to these studies, the following variables were correlated with poor outcome: early onset, severity of OCD symptoms, chronic course, poor social functioning at baseline, lifetime history of comorbid psychiatric and personality disorders, presence of parental Axis I psychiatric diagnosis, and delayed response to serotonin reuptake inhibitors in the beginning of the treatment. Due to the availability of new treatments, most patients with OCD can expect significant improvement, but not complete remission of the disorder. The reviewed follow-up studies support previous reports on the chronicity of OCD.

  4. A influência do alcoolismo no prognóstico e tratamento da tuberculose

    OpenAIRE

    Rubia Laine de Paula Andrade; Tereza Cristina Scatena Villa; Sandra Pillon

    2005-01-01

    Se llevó a cabo una revisión de la literatura para identificar artículos que muestran la asociación y la relación entre el alcoholismo y tuberculosis. El alcoholismo crónico se considera un importante factor de riesgo para el desarrollo de la tuberculosis, pues en estos pacientes se ha encontrado una alta incidencia y formas más avanzadas. Los alcohólicos presentan mayores tasas de abandono de tratamiento y alto riego de desarrollar efectos colaterales a los medicamentos antitu...

  5. Computing handbook information systems and information technology

    CERN Document Server

    Topi, Heikki

    2014-01-01

    Disciplinary Foundations and Global ImpactEvolving Discipline of Information Systems Heikki TopiDiscipline of Information Technology Barry M. Lunt and Han ReichgeltInformation Systems as a Practical Discipline Juhani IivariInformation Technology Han Reichgelt, Joseph J. Ekstrom, Art Gowan, and Barry M. LuntSociotechnical Approaches to the Study of Information Systems Steve Sawyer and Mohammad Hossein JarrahiIT and Global Development Erkki SutinenUsing ICT for Development, Societal Transformation, and Beyond Sherif KamelTechnical Foundations of Data and Database ManagementData Models Avi Silber

  6. A Model for Information

    Directory of Open Access Journals (Sweden)

    Paul Walton

    2014-09-01

    Full Text Available This paper uses an approach drawn from the ideas of computer systems modelling to produce a model for information itself. The model integrates evolutionary, static and dynamic views of information and highlights the relationship between symbolic content and the physical world. The model includes what information technology practitioners call “non-functional” attributes, which, for information, include information quality and information friction. The concepts developed in the model enable a richer understanding of Floridi’s questions “what is information?” and “the informational circle: how can information be assessed?” (which he numbers P1 and P12.

  7. Dynamics of Information Systems

    CERN Document Server

    Hirsch, Michael J; Murphey, Robert

    2010-01-01

    Our understanding of information and information dynamics has outgrown classical information theory. This book presents the research explaining the importance of information in the evolution of a distributed or networked system. It presents techniques for measuring the value or significance of information within the context of a system

  8. Technology Information Center

    International Nuclear Information System (INIS)

    Emerson, E.L.; Shepherd, E.W.; Minor, E.E.

    1980-01-01

    A Transportation Technology Center (TTC) has been established at Sandia to address the transportation of nuclear waste and spent fuel. The Technology Information Center (TIC) acts as TTC's clearing house for nuclear material transportation information. TIC's activities are divided into three activities: public information, policy information, and technical information. Some of the uses of TIC's activities are briefly outlined

  9. Information as Wealth.

    Science.gov (United States)

    Deruchie, Douglas M.

    1992-01-01

    Discusses the value of information-based services in today's global economy. The combination of information technology with library and information services at an international accounting and auditing firm is described; the Global Information Network is explained; and the importance of the appropriate use of information is discussed. (LRW)

  10. Building an Information Infrastructure.

    Science.gov (United States)

    Breivik, Patricia Senn

    1992-01-01

    College governing boards can promote good campus information management by understanding available services, monitoring changes and their relationship to priorities, supporting policies enhancing access to information, encouraging resource allocation for networking, promoting regional economic development through information use, and supporting…

  11. Stem Cell Information: Glossary

    Science.gov (United States)

    ... Tips Info Center Research Topics Federal Policy Glossary Stem Cell Information General Information Clinical Trials Funding Information Current ... here Home » Glossary Back to top Glossary Adult stem cell Astrocyte Blastocoel Blastocyst Bone marrow stromal cells Bone ...

  12. Carbon Monoxide Information Center

    Medline Plus

    Full Text Available ... RSS E-mail Inside CPSC Accessibility Privacy Policy Budget, Performances & Finance Open Government Freedom of Information (FOIA) ... Information Sitemap RSS E-mail Accessibility Privacy Policy Budget & Performance Open Government Freedom of Information (FOIA) USA. ...

  13. Animal Product Safety Information

    Science.gov (United States)

    ... Home Animal & Veterinary Safety & Health Product Safety Information Product Safety Information Share Tweet Linkedin Pin it More ... to report adverse experiences with veterinary drugs. Additional Product Information Questions and Answers: Evanger’s Dog and Cat ...

  14. Carbon Monoxide Information Center

    Medline Plus

    Full Text Available ... Education Centers Carbon Monoxide Information Center Carbon Monoxide Information Center En Español The Invisible Killer Carbon monoxide, ... Install one and check its batteries regularly. View Information About CO Alarms Other CO Topics Safety Tips ...

  15. Personal anticipated information need

    Directory of Open Access Journals (Sweden)

    H. Bruce

    2005-01-01

    Full Text Available Background. The role of personal information collections is a well known feature of personal information management. The World Wide Web has introduced to such collections ideas such as filing Web pages or noting their existence in 'Bookmarks' and 'Favourites'. Argument. It is suggested that personal information collections are created in anticipation of some future need for that information-personal, anticipated information need, which also underlies the design of formal information systems. Elaboration. Examination of the literature of information needs and information seeking behaviour leads to the formulation of five propositions that elaborate the concept of personal, anticipated information need. These propositions draw upon concepts such as uncertainty, predictability, sensitivity and the valuation of information sources. Conclusion. An individual's understanding of personal, anticipated information need and how this understanding guides the acquisition and management of personal information will determine the effectiveness of that collection.

  16. Informed consent - Providing information about prenatal examinations

    DEFF Research Database (Denmark)

    Dahl, Katja; Kesmodel, Ulrik; Hvidman, Lone

    as well.The review is based on systematic search strategy in the electronic databases Medline and Science Citation. Additional studies were identified through reference lists of individual papers obtained. Improving knowledge scores and reducing decisional conflict can be obtained by group counselling...... pregnant women about prenatal examinations. Women's knowledge, decisional conflict, satisfaction and anxiety will be explored as compared with different ways and different groups of health professionals providing information. To what extent information empowers informed decision making will be explored...

  17. Strategic information security

    CERN Document Server

    Wylder, John

    2003-01-01

    Introduction to Strategic Information SecurityWhat Does It Mean to Be Strategic? Information Security Defined The Security Professional's View of Information Security The Business View of Information SecurityChanges Affecting Business and Risk Management Strategic Security Strategic Security or Security Strategy?Monitoring and MeasurementMoving Forward ORGANIZATIONAL ISSUESThe Life Cycles of Security ManagersIntroductionThe Information Security Manager's Responsibilities The Evolution of Data Security to Information SecurityThe Repository Concept Changing Job Requirements Business Life Cycles

  18. Towards Information Security Awareness

    OpenAIRE

    Marius Petrescu; Delia Mioara Popescu; Nicoleta Sirbu

    2010-01-01

    Information security has come to be recognized as increasingly important because global communication and information systems allow a potentially large number of unauthorized users to access and possibly alter information from around the world. As the dependence on information systems grows, so the security of information networks becomes ever more critical to any entity, no matter if it is a company or a public institution. Information security involves both technology and people. Any securi...

  19. Information protection playbook

    CERN Document Server

    Kane, Greg

    2013-01-01

    The primary goal of the Information Protection Playbook is to serve as a comprehensive resource for information protection (IP) professionals who must provide adequate information security at a reasonable cost. It emphasizes a holistic view of IP: one that protects the applications, systems, and networks that deliver business information from failures of confidentiality, integrity, availability, trust and accountability, and privacy. Using the guidelines provided in the Information Protection Playbook, security and information technology (IT) managers will learn how to

  20. Personal anticipated information need

    OpenAIRE

    H. Bruce

    2005-01-01

    Background. The role of personal information collections is a well known feature of personal information management. The World Wide Web has introduced to such collections ideas such as filing Web pages or noting their existence in 'Bookmarks' and 'Favourites'. Argument. It is suggested that personal information collections are created in anticipation of some future need for that information-personal, anticipated information need, which also underlies the design of formal information systems. ...

  1. Energy information sheets

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-01

    The National Energy Information Center (NEIC), as part of its mission, provides energy information and referral assistance to Federal, State, and local governments, the academic community, business and industrial organizations, and the public. The Energy Information Sheets was developed to provide general information on various aspects of fuel production, prices, consumption, and capability. Additional information on related subject matter can be found in other Energy Information Administration (EIA) publications as referenced at the end of each sheet.

  2. Collaborative information seeking

    DEFF Research Database (Denmark)

    Hertzum, Morten

    2008-01-01

    Since common ground is pivotal to collaboration, this paper proposes to define collaborative information seeking as the combined activity of information seeking and collaborative grounding. While information-seeking activities are necessary for collaborating actors to acquire new information......, the activities involved in information seeking are often performed by varying subgroups of actors. Consequently, collaborative grounding is necessary to share information among collaborating actors and, thereby, establish and maintain the common ground necessary for their collaborative work. By focusing...... on the collaborative level, collaborative information seeking aims to avoid both individual reductionism and group reductionism, while at the same time recognizing that only some information and understanding need be shared....

  3. Aeronautical Information System Replacement -

    Data.gov (United States)

    Department of Transportation — Aeronautical Information System Replacement is a web-enabled, automation means for the collection and distribution of Service B messages, weather information, flight...

  4. Aeronautical Information System -

    Data.gov (United States)

    Department of Transportation — The Aeronautical Information System (AIS) is a leased weather automated system that provides a means of collecting and distributing aeronautical weather information...

  5. FFRRO Program Information

    Data.gov (United States)

    U.S. Environmental Protection Agency — This asset includes information related to Cleanups at Federal Facilities. Information is provided about contaminated federal facility sites in specific communities,...

  6. History of information science

    OpenAIRE

    Buckland, MK; Liu, Z

    1998-01-01

    This informative volume concentrates on the following areas: Historiography of Information Science; Paul Otlet and His Successors; Techniques, Tools, and Systems; People and Organizations; Theoretical Topics; and Literature.

  7. What is Quantum Information?

    Science.gov (United States)

    Lombardi, Olimpia; Fortin, Sebastian; Holik, Federico; López, Cristian

    2017-04-01

    Preface; Introduction; Part I. About the Concept of Information: 1. About the concept of information Sebastian Fortin and Olimpia Lombardi; 2. Representation, information, and theories of information Armond Duwell; 3. Information, communication, and manipulability Olimpia Lombardi and Cristian López; Part II. Information and quantum mechanics: 4. Quantum versus classical information Jeffrey Bub; 5. Quantum information and locality Dennis Dieks; 6. Pragmatic information in quantum mechanics Juan Roederer; 7. Interpretations of quantum theory: a map of madness Adán Cabello; Part III. Probability, Correlations, and Information: 8. On the tension between ontology and epistemology in quantum probabilities Amit Hagar; 9. Inferential versus dynamical conceptions of physics David Wallace; 10. Classical models for quantum information Federico Holik and Gustavo Martin Bosyk; 11. On the relative character of quantum correlations Guido Bellomo and Ángel Ricardo Plastino; Index.

  8. Information technology to support informal knowledge sharing

    NARCIS (Netherlands)

    Davison, R.M.; Ou, C.X.J.; Martinsons, M.G.

    2013-01-01

    The knowledge management (KM) literature largely focuses on the explicit and formal representation of knowledge in computer-based KM systems. Informal KM practices are widespread, but less is known about them. This paper aims to redress this imbalance by exploring the use of interactive information

  9. Information Impact | Journal of Information and Knowledge ...

    African Journals Online (AJOL)

    USER

    Information Impact | Journal of Information and Knowledge Management ... Abstract. This study was designed to determine the impact of collaboration on research and teaching .... delivery of quality instruction. ... for doing Collaborative projects, and there ... reveals that co-construction of knowledge ..... Get relevant materials.

  10. Information Impact: Journal of Information and Knowledge ...

    African Journals Online (AJOL)

    Information Impact: Journal of Information and Knowledge Management. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 7, No 2 (2016) >. Log in or Register to get access to full text downloads.

  11. The Information "Revolution": Information, Communications and Culture.

    Science.gov (United States)

    Ostry, Bernard

    Today's communications systems and technology facilitate the erosion of cultural differences, threatening cultural sovereignty. In the fifteenth century, the first information revolution created the concept of the nation-state with its unique cultural identity. The technology of the second information revolution, which has advanced video…

  12. Floridi's Philosophy of Information and Information Ethics

    DEFF Research Database (Denmark)

    Ess, Charles

    2009-01-01

    In order to evaluate Floridi's philosophy of information (PI) and correlative information ethics (IE) as potential frameworks for a global information and computing ethics (ICE), I review a range of important criticisms, defenses, and extensions of PI and IE, along with Floridi's responses to these......, as gathered together in a recent special issue of Ethics and Information Technology. A revised and expanded version of PI and IE emerges here, one that brings to the foreground PI's status as a philosophical naturalism—one with both current application and important potential in the specific domains...... of privacy and information law. Further, the pluralism already articulated by Floridi in his PI is now more explicitly coupled with an ethical pluralism in IE that will be enhanced through IE's further incorporation of discourse ethics. In this form, PI and IE emerge as still more robust frameworks...

  13. INFORMATION CULTURE AND INFORMATION SAFETY OF SCHOOLCHILDREN

    Directory of Open Access Journals (Sweden)

    E. G. Belyakova

    2017-01-01

    Full Text Available Introduction. The article is devoted to the problem of interaction between schoolchildren and possible informational risks transmitted on the Internet. Considering the lack of external filters on the way of harmful information streams, it is actually necessary to develop information culture of schoolchildren, their abilities to sensibly and critically interpret the information on the Internet, and choice of adequate behaviour models surfing the Web. The aim of the present research is to analyze the state of informational safety of schoolchildren while using the Internet; gaining an understanding of the role of external restrictions and opportunities of intrapersonal filtration of the harmful Internet content depending on children age. Methodology and research methods. The methodology of the research is based on modern methods aimed to consider the problem of personal socialization in modern information society. Thus, the Internet Initiatives Development Fund (IIDF questionnaire let the authors define the level of awareness of recipients on the problem under consideration. Results and scientific novelty. The theoretical analysis helped the authors predict the correlation of basic methods in order to guarantee personal safety of schoolchildren taking into account the process of maturity as well as the decrease of external filters that may stop harmful content. Empirical part of the research has enabled to reveal decrease in external control of staying of a child in network in the process of growing up against the background of restrictive attitudes prevalence among teachers and parents. Therefore, the research supposed to improve information culture of schoolchildren from the earliest ages encouraging them to sensibly and correctly interpret the information on the Internet. Practical significance. The practical recommendations to parents and teachers in order to improve informational personal safety of schoolchildren are proposed. The relevancy

  14. The Information Highway.

    Science.gov (United States)

    Gore, Al

    1994-01-01

    The new information marketplace is based on a network of wide, two-way highways comprised of private owners and developers, makers of information appliances (televisions, telephones, computers, and combinations of all three), information providers (local broadcasters, digital libraries, information service providers, and entrepreneurs), and…

  15. Information Systems Security Audit

    OpenAIRE

    Gheorghe Popescu; Veronica Adriana Popescu; Cristina Raluca Popescu

    2007-01-01

    The article covers:Defining an information system; benefits obtained by introducing new information technologies; IT management;Defining prerequisites, analysis, design, implementation of IS; Information security management system; aspects regarding IS security policy; Conceptual model of a security system; Auditing information security systems and network infrastructure security.

  16. Aquaculture Information Package

    Energy Technology Data Exchange (ETDEWEB)

    Boyd, T.; Rafferty, K. [editors

    1998-01-01

    This package of information is intended to provide background to developers of geothermal aquaculture projects. The material is divided into eight sections and includes information on market and price information for typical species, aquaculture water quality issues, typical species culture information, pond heat loss calculations, an aquaculture glossary, regional and university aquaculture offices and state aquaculture permit requirements.

  17. Understanding mobile information needs

    OpenAIRE

    Church, Karen; Smyth, Barry

    2008-01-01

    In this paper we describe the results of a four-week diary study of mobile information needs, focusing on the intent behind mobile needs and the importance on context on such needs. We identified three key intents among diary entries: informational, geographical and personal information management (PIM). Furthermore, we found many of these information needs have high temporal and location dependencies.

  18. Information science in transition

    CERN Document Server

    Gilchrist, Alan

    2013-01-01

    Are we at a turning point in digital information? The expansion of the internet is unprecedented. Will information science become part of computer science and does rise of the term informatics demonstrate convergence of information science and information technology - a convergence that must surely develop? This work reflects on such issues.

  19. Delaying information search

    Directory of Open Access Journals (Sweden)

    Yaniv Shani

    2012-11-01

    Full Text Available In three studies, we examined factors that may temporarily attenuate information search. People are generally curious and dislike uncertainty, which typically encourages them to look for relevant information. Despite these strong forces that promote information search, people sometimes deliberately delay obtaining valuable information. We find they may do so when they are concerned that the information might interfere with future pleasurable activities. Interestingly, the decision to search or to postpone searching for information is influenced not only by the value and importance of the information itself but also by well-being maintenance goals related to possible detrimental effects that negative knowledge may have on unrelated future plans.

  20. Handbook of information science

    CERN Document Server

    Stock, Wolfgang G

    2013-01-01

    Dealing with information is one of the vital skills in thetwenty-first century. It takes a fair degree of information savvy to create, represent and supply information as well as to search for and retrieve relevant knowledge. This Handbook is a basic work of information science, providing a comprehensive overview of the current state of information retrieval and knowledge representation. It addresses readers from all professions and scientific disciplines, but particularly scholars, practitioners and students of Information Science, Library Science, Computer Science, Information Management, an

  1. Aquaculture information package

    Energy Technology Data Exchange (ETDEWEB)

    Boyd, T.; Rafferty, K.

    1998-08-01

    This package of information is intended to provide background information to developers of geothermal aquaculture projects. The material is divided into eight sections and includes information on market and price information for typical species, aquaculture water quality issues, typical species culture information, pond heat loss calculations, an aquaculture glossary, regional and university aquaculture offices and state aquaculture permit requirements. A bibliography containing 68 references is also included.

  2. Information technology made simple

    CERN Document Server

    Carter, Roger

    1991-01-01

    Information Technology: Made Simple covers the full range of information technology topics, including more traditional subjects such as programming languages, data processing, and systems analysis. The book discusses information revolution, including topics about microchips, information processing operations, analog and digital systems, information processing system, and systems analysis. The text also describes computers, computer hardware, microprocessors, and microcomputers. The peripheral devices connected to the central processing unit; the main types of system software; application soft

  3. Information Aggregation in Organizations

    OpenAIRE

    Schulte, Elisabeth

    2006-01-01

    This dissertation contributes to the analysis of information aggregation procedures within organizations. Facing uncertainty about the consequences of a collective decision, information has to be aggregated before making a choice. Two main questions are addressed. Firstly, how well is an organization suited for the aggregation of decision-relevant information? Secondly, how should an organization be designed in order to aggregate information efficiently? The main part deals with information a...

  4. Electronic healthcare information security

    CERN Document Server

    Dube, Kudakwashe; Shoniregun, Charles A

    2010-01-01

    The ever-increasing healthcare expenditure and pressing demand for improved quality and efficiency of patient care services are driving innovation in healthcare information management. The domain of healthcare has become a challenging testing ground for information security due to the complex nature of healthcare information and individual privacy. ""Electronic Healthcare Information Security"" explores the challenges of e-healthcare information and security policy technologies. It evaluates the effectiveness of security and privacy implementation systems for anonymization methods and techniqu

  5. Information Warfare, Threats and Information Security

    Directory of Open Access Journals (Sweden)

    Dmitriy Nikolaevich Bespalov

    2014-01-01

    Full Text Available The article presents the opposite, but dependent on each other's reality - Revolutionary War information,information security goals and objectives of their study within the scheme "challenge-response", methodological and analytical support, the role of elites and the information society in promoting information security. One of the features of contemporaneityis the global spread of ICT, combined with poor governance and other difficulties in the construction of innovation infrastructures that are based on them in some countries. This leads to the reproduction of threats, primarily related to the ability to use ICT for purposes that are inconsistent with the objectives of maintaining international peace and security, compliance with the principles of non-use of force, non-interference in the internal affairs of states, etc. In this regard, include such terms as "a threat of information warfare", "information terrorism" and so forth. Information warfare, which stay in the policy declared the struggle for existence, and relationships are defined in terms of "friend-enemy", "ours-foreign". Superiority over the opponent or "capture of its territory" is the aim of political activity. And information security, serving activities similar process of political control, including a set of components, is a technology until their humanitarian. From the context and the decision itself is the ratio of the achieved results of information and political influence to the target - a positive image of Russia. Bringing its policy in line with the demands of a healthy public opinion provides conductivity of theauthorities initiatives in the country and increases the legitimacy of the Russian Federation actions in the world.

  6. Digital Information and Value

    Directory of Open Access Journals (Sweden)

    Paul Walton

    2015-11-01

    Full Text Available Digital information changes the ways in which people and organisations interact. This paper examines the nature of this change in the context of the author’s Model for Information (MfI. It investigates the relationship between outcomes and value, selection processes and some attributes of information and explores how this relationship changes in the move from analogue to digital information. Selection processes shape the evolution of information ecosystems in which conventions are established for the ways in which information is used. The conventions determine norms for information friction and information quality as well as the sources of information and channels used. Digital information reduces information friction, often dramatically, and changes information quality. The increasing use of analytics in business increasingly delivers predictive or prescriptive digital information. These changes are happening faster than information ecosystem conventions can change. The relationships established in the paper enable an analysis of, and guide changes to, these conventions enabling a more effective use of digital information.

  7. Information Impact: Journal of Information and Knowledge ...

    African Journals Online (AJOL)

    References must conform to the 6th edition of the Publication Manual of ... Book. Chapman, L.(2001). Managing acquisition in libraries and information services. ... For electronic resources, please see APA guidelines at www.apastyle.org ...

  8. Information Impact: Journal of Information and Knowledge ...

    African Journals Online (AJOL)

    Meeting the information needs of remote library users: the case of University of Maiduguri Distance Learning Programme · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Adam Gambo Saleh, 1-16 ...

  9. Information technology acceptance in health information management.

    Science.gov (United States)

    Abdekhoda, M; Ahmadi, M; Dehnad, A; Hosseini, A F

    2014-01-01

    User acceptance of information technology has been a significant area of research for more than two decades in the field of information technology. This study assessed the acceptance of information technology in the context of Health Information Management (HIM) by utilizing Technology Acceptance Model (TAM) which was modified and applied to assess user acceptance of health information technology as well as viability of TAM as a research construct in the context of HIM. This was a descriptive- analytical study in which a sample of 187 personnel from a population of 363 personnel, working in medical records departments of hospitals affiliated to Tehran University of Medical Sciences, was selected. Users' perception of applying information technology was studied by a researcher-developed questionnaire. Collected data were analyzed by SPSS software (version16) using descriptive statistics and regression analysis. The results suggest that TAM is a useful construct to assess user acceptance of information technology in the context of HIM. The findings also evidenced the perceived ease of use (PEOU) and perceived usefulness (PE) were positively associated with favorable users' attitudes towards HIM. PU was relatively more associated (r= 0.22, p = 0.05) than PEOU (r = 0.014, p = 0.05) with favorable user attitudes towards HIM. Users' perception of usefulness and ease of use are important determinants providing the incentive for users to accept information technologies when the application of a successful HIM system is attempted. The findings of the present study suggest that user acceptance is a key element and should subsequently be the major concern of health organizations and health policy makers.

  10. The Informal Sector

    OpenAIRE

    Áureo de Paula; José A. Scheinkman

    2007-01-01

    This paper investigates the determinants of informal economic activity. We present two equilibrium models of informality and test their implications using a survey of 48,000+ small firms in Brazil. We define informality as tax avoidance; firms in the informal sector avoid tax payments but suffer other limitations. In the first model there is a single industry and informal firms face a higher cost of capital and a limitation on size. As a result informal firms are smaller and have a lower capi...

  11. Energy information sheets

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-02

    The National Energy Information Center (NEIC), as part of its mission, provides energy information and referral assistance to Federal, State, and local governments, the academic community, business and industrial organizations, and the general public. Written for the general public, the EIA publication Energy Information Sheets was developed to provide information on various aspects of fuel production, prices, consumption and capability. The information contained herein pertains to energy data as of December 1991. Additional information on related subject matter can be found in other EIA publications as referenced at the end of each sheet.

  12. Towards Information Lasers

    Directory of Open Access Journals (Sweden)

    Andrei Khrennikov

    2015-10-01

    Full Text Available Recently, the methods of quantum theory (QT, especially quantum information and probability, started to be widely applied outside of physics: in cognitive, social and political sciences, psychology, economics, finances, decision making, molecular biology and genetics. Such models can be called quantum-like, in contrast to real quantum physical cognitive and biological models. Quantum-like means that only the information and probability structures of QT are explored. This approach matches the information interpretation of QT well (e.g., Zeilinger and Brukner, Fuchs and Mermin, D’Ariano, as well as the informational viewpoint on physics in general (e.g., Wheeler’s “it from bit” paradigm. In this paper, we propose a quantum-like model of an information laser by precessing the assumptions on the structure of state spaces of information processors, “information atoms” (i-atoms and information fields. The basic assumption is the discrete structure of state spaces related to quantization of an information analog of energy. To analyze a possible structure of the state space of i-atoms leading to the possibility to create information lasers, we have to develop a purely information version of quantum thermodynamics. We did this by placing the main attention on the derivation of the conditions for the equilibrium of information exchange between i-atoms and a quantized information field.

  13. Sleep Apnea Information Page

    Science.gov (United States)

    ... Page You are here Home » Disorders » All Disorders Sleep Apnea Information Page Sleep Apnea Information Page What research is being done? ... Institutes of Health (NIH) conduct research related to sleep apnea in laboratories at the NIH, and also ...

  14. Information manager vol 10

    African Journals Online (AJOL)

    Library _info_Sc_ 1

    1989-05-11

    May 11, 1989 ... This study explored rural-based library and information services. The location was .... However, following the passage of Imo State Law on. Local Government ... What are the information sources used to satisfy these needs? 3.

  15. Informal Unemployment and Education

    DEFF Research Database (Denmark)

    Kolm, Anne-Sofie; Larsen, Birthe

    This paper develops a four sector equilibrium search and matching model with informal sector employment opportunities and educational choice. We show that underground activities reduce educational attainments if informal employment opportunities mainly are available to low educated workers. More ...

  16. Carbon Monoxide Information Center

    Medline Plus

    Full Text Available ... Inside CPSC Accessibility Privacy Policy Budget, Performances & Finance Open Government Freedom of Information (FOIA) Inspector General No ... RSS E-mail Accessibility Privacy Policy Budget & Performance Open Government Freedom of Information (FOIA) USA.gov CPSC. ...

  17. Geographical information systems

    DEFF Research Database (Denmark)

    Möller, Bernd

    2004-01-01

    The chapter gives an introduction to Geographical Information Systems (GIS) with particular focus on their application within environmental management.......The chapter gives an introduction to Geographical Information Systems (GIS) with particular focus on their application within environmental management....

  18. Carbon Monoxide Information Center

    Medline Plus

    Full Text Available ... Accessibility Privacy Policy Budget, Performances & Finance Open Government Freedom of Information (FOIA) Inspector General No Fear Act ... mail Accessibility Privacy Policy Budget & Performance Open Government Freedom of Information (FOIA) USA.gov CPSC.gov is ...

  19. Integrated inventory information system

    Digital Repository Service at National Institute of Oceanography (India)

    Sarupria, J.S.; Kunte, P.D.

    The nature of oceanographic data and the management of inventory level information are described in Integrated Inventory Information System (IIIS). It is shown how a ROSCOPO (report on observations/samples collected during oceanographic programme...

  20. Congenital Heart Information Network

    Science.gov (United States)

    ... heart defects. Important Notice The Congenital Heart Information Network website is temporarily out of service. Please join ... and Uwe Baemayr for The Congenital Heart Information Network Exempt organization under Section 501(c)3. Copyright © ...

  1. Indiana Health Information Exchange

    Science.gov (United States)

    The Indiana Health Information Exchange is comprised of various Indiana health care institutions, established to help improve patient safety and is recognized as a best practice for health information exchange.

  2. International cooperative information systems

    International Nuclear Information System (INIS)

    1980-01-01

    Developing countries need mechanisms by which the information they generate themselves and development information from the rest of the world can be retrieved. The international cooperative information system is such a mechanism. Delegates to the Seminar on International Cooperative Information Systems were informed about various existing systems (INIS, AGRIS, INFOTERRA, TCDC/INRES, POPIN, DEVSIS, and INPADROC), some specialized information systems and services (CDS/ISIS and the Cassava Information Centre), and computer programs for information processing (INIS/AGRIS, CDS/ISIS, and MINISIS). The participants suggested some changes that should be made on both the national and the international levels to ensure that these systems meet the needs of developing countries more effectively. (LL)

  3. Informed Food Choice

    DEFF Research Database (Denmark)

    Coff, Christian

    2014-01-01

    of informed food choice. An informed food choice is an enlightened food choice made by the individual based on the information made available. Food choices are made when shopping for food or when eating/drinking, and information is believed to give clarity to the options by increasing market transparency......Food production and consumption influence health, the environment, social structures, etc. For this reason consumers are increasingly interested in information about these effects. Disclosure of information about the consequences of food production and consumption is essential for the idea......, supporting rationality (the best choice), consumers’ self-governance (autonomy) and life coherence (integrity). On a practical level, informed food choice remains an ideal to strive for, as information on food often is inadequate....

  4. Changing Information Retrieval Behaviours

    DEFF Research Database (Denmark)

    Constantiou, Ioanna D.; Lehrer, Christiane; Hess, Thomas

    2014-01-01

    on the continuance of LBS use and indicate changes in individuals' information retrieval behaviours in everyday life. In particular, the distinct value dimension of LBS in specific contexts of use changes individuals' behaviours towards accessing location-related information....

  5. PDQ® Cancer Information

    Science.gov (United States)

    An NCI database that contains the latest information about cancer treatment, screening, prevention, genetics, supportive care, and complementary and alternative medicine, plus drug information and a dictionary of cancer terms.

  6. Carbon Monoxide Information Center

    Medline Plus

    Full Text Available ... Us Sitemap RSS E-mail Inside CPSC Accessibility Privacy Policy Budget, Performances & Finance Open Government Freedom of ... News and Information Sitemap RSS E-mail Accessibility Privacy Policy Budget & Performance Open Government Freedom of Information ( ...

  7. Newcomer information seeking

    DEFF Research Database (Denmark)

    Moring, Camilla Elisabeth

    2017-01-01

    Introduction: Research on socialization and learning processes among organizational newcomers is offering valuable insight into the role of information seeking in the workplace, and to why, and how newcomers seek information when entering a new organization. Analysis: The aim of the paper is to o...... and corporeal information sources newcomers learn about the organizational practice, and the knowledge needed in order to develop as a competent practitioner and become a full member of the organization.......Introduction: Research on socialization and learning processes among organizational newcomers is offering valuable insight into the role of information seeking in the workplace, and to why, and how newcomers seek information when entering a new organization. Analysis: The aim of the paper...... is to outline and discuss the significance of information seeking in newcomer socialization and learning, and analyse how different approaches influence our understanding of the role of information seeking in the workplace. Results: It is argued, that a development in research on newcomer information seeking...

  8. What is quantum information ?

    CERN Document Server

    Fortin, Sebastian; Holik, Federico; López, Cristian

    2017-01-01

    Combining physics and philosophy, this is a uniquely interdisciplinary examination of quantum information science which provides an up-to-date examination of developments in this field. The authors provide coherent definitions and theories of information, taking clearly defined approaches to considering information in connection with quantum mechanics, probability, and correlations. Concepts addressed include entanglement of quantum states, the relation of quantum correlations to quantum information, and the meaning of the informational approach for the foundations of quantum mechanics. Furthermore, the mathematical concept of information in the communicational context, and the notion of pragmatic information are considered. Suitable as both a discussion of the conceptual and philosophical problems of this field and a comprehensive stand-alone introduction, this book will benefit both experienced and new researchers in quantum information and the philosophy of physics.

  9. Senior Information Officials Standard

    Science.gov (United States)

    This document establishes the (SIOs) as the Environmental Protection Agency’s (EPA) primary points of accountability for the effective oversight, coordination, and management of information and information technology (IT)

  10. Carbon Monoxide Information Center

    Medline Plus

    Full Text Available ... E-mail Inside CPSC Accessibility Privacy Policy Budget, Performances & Finance Open Government Freedom of Information (FOIA) Inspector ... Sitemap RSS E-mail Accessibility Privacy Policy Budget & Performance Open Government Freedom of Information (FOIA) USA.gov ...

  11. Carbon Monoxide Information Center

    Medline Plus

    Full Text Available ... Education Safety Education Centers Carbon Monoxide Information Center Carbon Monoxide Information Center En Español The Invisible Killer Carbon monoxide, also known as CO, is called the " ...

  12. RCRA Facility Information

    Data.gov (United States)

    U.S. Environmental Protection Agency — This asset includes hazardous waste information, which is mostly contained in the Resource Conservation and Recovery Act Information (RCRAInfo) System, a national...

  13. Repositioning Information Science.

    OpenAIRE

    Ibekwe-Sanjuan , Fidelia; Buckland , Michael; Latham , Kiersten

    2010-01-01

    International audience; During the twentieth century there was a strong desire for information studies to become scientific, to move from librarianship, bibliography, and documentation to an information science. In 1968 the American Documentation Institute was renamed American Society for Information Science. By the twenty-first century, however, departments of (library and) information science had turned instead towards the social sciences, but have not been successful in providing a coheren...

  14. Designing information systems

    CERN Document Server

    Blethyn, Stanley G

    2014-01-01

    Designing Information Systems focuses on the processes, methodologies, and approaches involved in designing information systems. The book first describes systems, management and control, and how to design information systems. Discussions focus on documents produced from the functional construction function, users, operators, analysts, programmers and others, process management and control, levels of management, open systems, design of management information systems, and business system description, partitioning, and leveling. The text then takes a look at functional specification and functiona

  15. Dynamic Strategic Information Transmission

    OpenAIRE

    Mikhail Golosov; Vasiliki Skreta; Aleh Tsyvinski; Andrea Wilson

    2011-01-01

    This paper studies strategic information transmission in a dynamic environment where, each period, a privately informed expert sends a message and a decision maker takes an action. Our main result is that, in contrast to a static environment, full information revelation is possible. The gradual revelation of information and the eventual full revelation is supported by the dynamic rewards and punishments. The construction of a fully revealing equilibrium relies on two key features. The first f...

  16. Public informations guidelines

    International Nuclear Information System (INIS)

    1986-06-01

    The purpose of these Public Information Guidelines is to provide principles for the implementation of the NWPA mandate and the Mission Plan requirements for the provision of public information. These Guidelines set forth the public information policy to be followed by all Office of Civilian Radioactive Waste Management (OCRWM) performance components. The OCRWM offices should observe these Guidelines in shaping and conducting public information activities

  17. Public informations guidelines

    Energy Technology Data Exchange (ETDEWEB)

    None

    1986-06-01

    The purpose of these Public Information Guidelines is to provide principles for the implementation of the NWPA mandate and the Mission Plan requirements for the provision of public information. These Guidelines set forth the public information policy to be followed by all Office of Civilian Radioactive Waste Management (OCRWM) performance components. The OCRWM offices should observe these Guidelines in shaping and conducting public information activities.

  18. Computer information systems framework

    International Nuclear Information System (INIS)

    Shahabuddin, S.

    1989-01-01

    Management information systems (MIS) is a commonly used term in computer profession. The new information technology has caused management to expect more from computer. The process of supplying information follows a well defined procedure. MIS should be capable for providing usable information to the various areas and levels of organization. MIS is different from data processing. MIS and business hierarchy provides a good framework for many organization which are using computers. (A.B.)

  19. Natural Information Processing Systems

    OpenAIRE

    John Sweller; Susan Sweller

    2006-01-01

    Natural information processing systems such as biological evolution and human cognition organize information used to govern the activities of natural entities. When dealing with biologically secondary information, these systems can be specified by five common principles that we propose underlie natural information processing systems. The principles equate: (1) human long-term memory with a genome; (2) learning from other humans with biological reproduction; (3) problem solving through random ...

  20. Information Services Directory

    International Nuclear Information System (INIS)

    1986-08-01

    The Information Services Directory is intended to facilitate participation by states, affected Indian tribes and the public in the Civilian Radioactive Waste Management Program. The Directory is produced by the Information Services Division of the OCRWM's Office of Policy and Outreach and will be updated periodically. It is a reference document that identifies the sources of available program information

  1. Information Design Theories

    Science.gov (United States)

    Pettersson, Rune

    2014-01-01

    Information design has practical and theoretical components. As an academic discipline we may view information design as a combined discipline, a practical theory, or as a theoretical practice. So far information design has incorporated facts, influences, methods, practices, principles, processes, strategies, and tools from a large number of…

  2. Information Manager (The)

    African Journals Online (AJOL)

    The Information Manager is an Interdisciplinary Journal which provides a forum for the ... It serves as a forum for new research in information dissemination and communication processes in general, The basic focus of Information manager are: i. to ... Influence of Mac Arthur Journal Donation Project on Serial Resources of ...

  3. Informed Consent and Routinisation

    DEFF Research Database (Denmark)

    Ploug, Thomas; Holm, Søren

    2013-01-01

    provide evidence of the routinisation of informed consent in various types of interaction on the internet; among these, the routinisation of consent to the exchange of health related information. We also provide evidence that the extent of the routinisation of informed consent is dependent...

  4. Information Services Directory

    International Nuclear Information System (INIS)

    1985-11-01

    The Information Services directory is intended to facilitate participation by states, affected Indian tribes and the public in the Civilian Radioactive Waste Management program. The Directory is produced by the Information Services Division of the OCRWM's Office of Policy and Outreach and will be updated periodically. It is a reference document that identifies the sources of available program information

  5. Community Information Systems.

    Science.gov (United States)

    Freeman, Andrew

    Information is provided on technological and social trends as background for a workshop designed to heighten the consciousness of workers in community information systems. Initially, the basic terminology is considered in its implications for an integrated perspective of community information systems, with particular attention given to the meaning…

  6. Security classification of information

    Energy Technology Data Exchange (ETDEWEB)

    Quist, A.S.

    1993-04-01

    This document is the second of a planned four-volume work that comprehensively discusses the security classification of information. The main focus of Volume 2 is on the principles for classification of information. Included herein are descriptions of the two major types of information that governments classify for national security reasons (subjective and objective information), guidance to use when determining whether information under consideration for classification is controlled by the government (a necessary requirement for classification to be effective), information disclosure risks and benefits (the benefits and costs of classification), standards to use when balancing information disclosure risks and benefits, guidance for assigning classification levels (Top Secret, Secret, or Confidential) to classified information, guidance for determining how long information should be classified (classification duration), classification of associations of information, classification of compilations of information, and principles for declassifying and downgrading information. Rules or principles of certain areas of our legal system (e.g., trade secret law) are sometimes mentioned to .provide added support to some of those classification principles.

  7. Connectionist Interaction Information Retrieval.

    Science.gov (United States)

    Dominich, Sandor

    2003-01-01

    Discussion of connectionist views for adaptive clustering in information retrieval focuses on a connectionist clustering technique and activation spreading-based information retrieval model using the interaction information retrieval method. Presents theoretical as well as simulation results as regards computational complexity and includes…

  8. Information Retrieval Models

    NARCIS (Netherlands)

    Hiemstra, Djoerd; Göker, Ayse; Davies, John

    2009-01-01

    Many applications that handle information on the internet would be completely inadequate without the support of information retrieval technology. How would we find information on the world wide web if there were no web search engines? How would we manage our email without spam filtering? Much of the

  9. Teaching Information Technology Law

    Science.gov (United States)

    Taylor, M. J.; Jones, R. P.; Haggerty, J.; Gresty, D.

    2009-01-01

    In this paper we discuss an approach to the teaching of information technology law to higher education computing students that attempts to prepare them for professional computing practice. As information technology has become ubiquitous its interactions with the law have become more numerous. Information technology practitioners, and in particular…

  10. Recommendation with Contextual Information

    Science.gov (United States)

    Huang, Jia

    2014-01-01

    Information retrieval (IR) systems have tremendously broaden users' access to information. However, users need to select their needs from trillions of information indexed daily. Due to the "semantic gap" between queries and indexed terms in IR system, whether users can satisfy their needs depends on whether they use the correct terms as…

  11. The Information Search

    Science.gov (United States)

    Doraiswamy, Uma

    2011-01-01

    This paper in the form of story discusses a college student's information search process. In this story we see Kuhlthau's information search process: initiation, selection, exploration, formulation, collection, and presentation. Katie is a student who goes in search of information for her class research paper. Katie's class readings, her interest…

  12. Geothermal Greenhouse Information Package

    Energy Technology Data Exchange (ETDEWEB)

    Rafferty, K. [P.E.; Boyd, T. [ed.

    1997-01-01

    This package of information is intended to provide a foundation of background information for developers of geothermal greenhouses. The material is divided into seven sections covering such issues as crop culture and prices, operating costs for greenhouses, heating system design, vendors and a list of other sources of information.

  13. Ethics of Information Supply.

    Science.gov (United States)

    Oppenheim, Charles

    This discussion of the ethics of the information process provides a brief review of the process of information supply and flow, primarily in science and technology; looks at various points in the flow of information; and highlights particular ethical concerns. Facets of the process discussed in more detail include ways in which some scientists…

  14. Museums, Environments, Information

    NARCIS (Netherlands)

    Koutamanis, A.

    2015-01-01

    Modern digital media already permeate the physical world. The portability of information devices and the ubiquity of networks allow us to access information practically anyplace, creating digital overlays on reality. This also allows us to bring information we routinely archive in museums and

  15. Evaluating Health Information

    Science.gov (United States)

    Millions of consumers get health information from magazines, TV or the Internet. Some of the information is reliable and up to date; some is not. How can ... the site have an editorial board? Is the information reviewed before it is posted? Be skeptical. Things ...

  16. Is Information Still Relevant?

    Science.gov (United States)

    Ma, Lia

    2013-01-01

    Introduction: The term "information" in information science does not share the characteristics of those of a nomenclature: it does not bear a generally accepted definition and it does not serve as the bases and assumptions for research studies. As the data deluge has arrived, is the concept of information still relevant for information…

  17. Information Architecture: Looking Ahead.

    Science.gov (United States)

    Rosenfeld, Louis

    2002-01-01

    Considers the future of the field of information architecture. Highlights include a comparison with the growth of the field of professional management; the design of information systems since the Web; more demanding users; the need for an interdisciplinary approach; and how to define information architecture. (LRW)

  18. Information network architectures

    Science.gov (United States)

    Murray, N. D.

    1985-01-01

    Graphs, charts, diagrams and outlines of information relative to information network architectures for advanced aerospace missions, such as the Space Station, are presented. Local area information networks are considered a likely technology solution. The principle needs for the network are listed.

  19. Energy information directory 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-10-01

    The National Energy Information Center provides energy information and referral assistance to Federal, State, and local governments, the academic community, business and industrial organizations, and the general public. This Energy Information Directory is used to assist the Center staff as well as other DOE staff in directing inquires to the proper offices.

  20. Information technology ethics

    DEFF Research Database (Denmark)

    Hongladarom, Soraj; Ess, Charles

    This book was the first publication to take a genuinely global approach to the diverse ethical issues evoked by Information and Communication Technologies and their possible resolutions. Readers will gain a greater appreciation for the problems and possibilities of genuinely global information...... ethics, which are urgently needed as information and communication technologies continue their exponential growth...

  1. Methods of information processing

    Energy Technology Data Exchange (ETDEWEB)

    Kosarev, Yu G; Gusev, V D

    1978-01-01

    Works are presented on automation systems for editing and publishing operations by methods of processing symbol information and information contained in training selection (ranking of objectives by promise, classification algorithm of tones and noise). The book will be of interest to specialists in the automation of processing textural information, programming, and pattern recognition.

  2. Information, Precedent, and Statute

    NARCIS (Netherlands)

    O. Yalnazov (Orlin)

    2017-01-01

    textabstractI compare precedent and statute in cost-effectiveness terms. To make laws, a lawmaker needs information. Information has a cost. That cost is sensitive to the choice of law production technology. The orthodoxy is that the courts acquire information more cheaply. Litigants volunteer it in

  3. Personal, Anticipated Information Need

    Science.gov (United States)

    Bruce, Harry

    2005-01-01

    Background: The role of personal information collections is a well known feature of personal information management. The World Wide Web has introduced to such collections ideas such as filing Web pages or noting their existence in "Bookmarks" and "Favourites". Argument: It is suggested that personal information collections are…

  4. Mobile Student Information System

    Science.gov (United States)

    Asif, Muhammad; Krogstie, John

    2011-01-01

    Purpose: A mobile student information system (MSIS) based on mobile computing and context-aware application concepts can provide more user-centric information services to students. The purpose of this paper is to describe a system for providing relevant information to students on a mobile platform. Design/methodology/approach: The research…

  5. Lofar information system design

    NARCIS (Netherlands)

    Valentijn, E.; Belikov, A. N.

    2009-01-01

    The Lofar Information System is a solution for Lofar Long Term Archive that is capable to store and handle PBs of raw and processed data. The newly created information system is based on Astro-WISE - the information system for wide field astronomy. We review an adaptation of Astro-WISE for the new

  6. Information system metaphors

    NARCIS (Netherlands)

    Gazendam, H.W.M.

    1999-01-01

    Metaphors are useful because they are efficient: they transfer a complex of meaning in a few words. Information systems are social constructs. Therefore, metaphors seem to be especially useful for explaining the space of possible meaning complexes or designs of information systems. Three information

  7. Does Information Change Behavior?

    OpenAIRE

    Huffman, Wallace

    2009-01-01

    This paper reviews and synthesizes the theory of information economics and empirical evidence on how information changes the behavior of consumers, households and firms. I show that consumers respond to new information in food experiments but perhaps not in retirement account management. Some seeming perverse consumer/investor decision making may be a result of a complex decision with a low expected payoff.

  8. Information manager vol 10

    African Journals Online (AJOL)

    Library _info_Sc_ 1

    The Perception of Librarians As Sources Of Information On HIV/AIDS By ... the librarian is confined to the library. ... is to offer information services that can assist information users to meet their needs at the right time and in the right format. ... relationships (Sande and Volbering,1992). ..... Education for Students: A Proposal for.

  9. Dynamic statistical information theory

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    In recent years we extended Shannon static statistical information theory to dynamic processes and established a Shannon dynamic statistical information theory, whose core is the evolution law of dynamic entropy and dynamic information. We also proposed a corresponding Boltzmman dynamic statistical information theory. Based on the fact that the state variable evolution equation of respective dynamic systems, i.e. Fokker-Planck equation and Liouville diffusion equation can be regarded as their information symbol evolution equation, we derived the nonlinear evolution equations of Shannon dynamic entropy density and dynamic information density and the nonlinear evolution equations of Boltzmann dynamic entropy density and dynamic information density, that describe respectively the evolution law of dynamic entropy and dynamic information. The evolution equations of these two kinds of dynamic entropies and dynamic informations show in unison that the time rate of change of dynamic entropy densities is caused by their drift, diffusion and production in state variable space inside the systems and coordinate space in the transmission processes; and that the time rate of change of dynamic information densities originates from their drift, diffusion and dissipation in state variable space inside the systems and coordinate space in the transmission processes. Entropy and information have been combined with the state and its law of motion of the systems. Furthermore we presented the formulas of two kinds of entropy production rates and information dissipation rates, the expressions of two kinds of drift information flows and diffusion information flows. We proved that two kinds of information dissipation rates (or the decrease rates of the total information) were equal to their corresponding entropy production rates (or the increase rates of the total entropy) in the same dynamic system. We obtained the formulas of two kinds of dynamic mutual informations and dynamic channel

  10. Information society studies

    CERN Document Server

    Duff, Alistair S

    2013-01-01

    We are often told that we are ""living in an information society"" or that we are ""information workers."" But what exactly do these claims mean, and how might they be verified? In this important methodological study, Alistair S. Duff cuts through the rhetoric to get to the bottom of the ""information society thesis."" Wide-ranging in coverage, this study will be of interest to scholars in information science, communication and media studies and social theory. It is a key text for the newly-unified specialism of information society studies, and an indispensable guide to the future of this disc

  11. Management of information organizations

    CERN Document Server

    Afzal, Waseem

    2012-01-01

    This book is a significant step towards developing a body of management knowledge pertinent to the context of Library Information Science (LIS) and provides a succinct but deep account of management and information organizations. Management of Information Organizations presents a broad view of the information organizations and the nature of management in these organizations, and how information professionals are affected by such management systems. The book equips the reader with the knowledge that will enable them to develop a strong intellectual foundation relating to management and its mani

  12. The Information Society

    Directory of Open Access Journals (Sweden)

    Hiranya Nath

    2017-03-01

    Full Text Available This article briefly discusses various definitions and concepts of the so-called information society. The term information society has been proposed to refer to the post-industrial society in which information plays a pivotal role. The definitions that have been proposed over the years highlight five underlying characterisations of an information society: technological, economic, sociological, spatial, and cultural. This article discusses those characteristics. While the emergence of an information society may be just a figment of one’s imagination, the concept could be a good organising principle to describe and analyse the changes of the past 50 years and of the future in the 21st century.

  13. Information behaviour and practice

    CERN Document Server

    Rafferty, Pauline; Baker, David

    2015-01-01

    This special issue explores information behaviour and practice in general, and specifically focuses on the implications for library and information services. Information seeking behaviour and information practice remain areas of importance in information science and librarianship, perhaps even more so in the digital age. This special issue is an opportunity to share ideas and scholarship and to explore models and methods. The papers chosen for inclusion cover a range of topics and approach them from a number of different epistemological and methodological positions demonstrating the liveliness

  14. Nuclear Information Democratization

    International Nuclear Information System (INIS)

    Savić, Dobrica

    2013-01-01

    Nuclear information (Nl) interests people for many reasons, with energy supply, safety, and security being at the top of the list. Democratizing nuclear information has its roots in the growth of a knowledge-based economy, the knowledge worker as a user of nuclear information, developments in information and communication technologies (ICT), and the impact of internet growth. Results of democratization are apparent in the process of information creation, in how nuclear information is distributed and accessed, and in the conditions for using the information found. The International Nuclear Information System (INIS) both reflects and contributes to these trends. Nuclear information falls under the overall umbrella of scientific and technical information (STI). It is highly specialized, but it follows general principles and trends of STI. The world of STI has its own culture and its own long-established rules of use and existence. These have brought us many inventions and improvements, introduced important technological changes, and made our lives and work much easier and more pleasurable. However, the world is constantly changing, and the traditional closed STI environment, including the world of nuclear information, is not keeping up with today’s changes. (author)

  15. Informed Consent in Dentistry.

    Science.gov (United States)

    Reid, Kevin I

    2017-03-01

    A review of literature regarding informed consent in dentistry reveals a paucity of information and minimal scholarship devoted to this subject. But this begs the question about informed consent somehow being different for dentistry than for medicine or other healthcare delivery. My account draws distinctions where appropriate but is rooted in the premise that informed consent is an ethical construct applicable to vulnerable people as patients independent of what type of treatment or body part being considered. This paper highlights the crucial importance of the process of informed consent and refusal in dentistry, underscoring its important place in oral healthcare. This paper will not address the unique circumstances involving consent in those without capacity or focus on informed consent in the research setting; our focus will be on those patients with full decisionmaking capacity in the clinical setting. I will emphasize the importance of disclosure of treatment options and highlight the benefits of shared-decision-making in the informed consent process.

  16. Shipping Information Pipeline

    DEFF Research Database (Denmark)

    Jensen, Thomas

    to creating a more efficient shipping industry, and a number of critical issues are identified. These include that shipments depend on shipping information, that shipments often are delayed due to issues with documentation, that EDI messages account for only a minor part of the needed information......This thesis applies theoretical perspectives from the Information Systems (IS) research field to propose how Information Technology (IT) can improve containerized shipping. This question is addressed by developing a set of design principles for an information infrastructure for sharing shipping...... information named the Shipping Information Pipeline (SIP). Review of the literature revealed that IS research prescribed a set of meta-design principles, including digitalization and digital collaboration by implementation of Inter-Organizational Systems based on Electronic Data Interchange (EDI) messages...

  17. Information Impact: Journal of Information and Knowledge ...

    African Journals Online (AJOL)

    Analytical study on availability of information and communication technology facilities in selected Nigerian university libraries · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. William O. Nkanu, Ebong N. Nkebem, Victoria A. Iyishu, Christopher E. Ogar ...

  18. Information Assurance and the Information Society

    NARCIS (Netherlands)

    Luiijf, H.A.M.

    1998-01-01

    Society is on the verge of a new era: the information age. Economical changes, a new way of looking at services and new types of conflict are forecasted. Some glimpses of these changes were noticed during the Persian Gulf War. Government decision units, organisations, society and critical industries

  19. Information Impact: Journal of Information and Knowledge ...

    African Journals Online (AJOL)

    Information Impact: Journal of Information and Knowledge management

    Five (5) research questions guided the study and three hypotheses were tested at 0.05 level of ... key factor of knowledge management is knowledge sharing. ... difference has been recorded in terms of skills acquisition, information literacy, classroom ... However, little is known about knowledge-sharing strategies and their ...

  20. Application of information technology infrastructure in information ...

    African Journals Online (AJOL)

    The study investigated the application of infotech infrastructure in information processing for enhancing workplace safety in Rivers State. In view of this, the study was a research survey design. The population of the study comprised 600 oil company workers in Rivers State. A-30% basis was used to randomly select the ...

  1. Information Impact: Journal of Information and Knowledge ...

    African Journals Online (AJOL)

    Contributions of agriculture and veterinary complex of Ahmadu Bello University, Zaria to the dissemination of agricultural information: a bibliometric analysis · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Gabriel M. Kasa, Ibrahim Umar, Maimuna Izah, 51-59 ...

  2. Information Impact | Journal of Information and Knowledge ...

    African Journals Online (AJOL)

    Information Impact | Journal of Information and Knowledge Management

    the students was not library and information science they all had their career prior their ... boils down to a career decision-making process”. That is .... choose secretarial option do so on the account of their failure to be registered in accounting.

  3. Information Assurance and the Information Society

    NARCIS (Netherlands)

    Luiijf, H.A.M.

    1999-01-01

    Society is on the verge of a new era: the information age. Economical changes, a new way of looking at services and new types of conflict are forecasted. Some glimpses of these changes were noticed during the Persian Gulf War. Government decision units, organisations, society and critical industries

  4. Information Management: Enhancing Information Discovery and Information Availability

    International Nuclear Information System (INIS)

    Nimfuehr, W.

    2015-01-01

    IBM Security Intelligence with Analytics of massive data provides exceptional threat and risk detection, combining deep security expertise with analytical insights on a massive scale. For forward-leaning organizations seeking advanced insight into security risks, the IBM solution -- Security Intelligence Platform for massive data -- provides a comprehensive, integrated approach that combines real-time correlation for continuous insight, custom analytics across massive structured and unstructured data, and forensic capabilities for irrefutable evidence. The combination can help you address advanced persistent threats, fraud and insider threats. The IBM solution is designed to widening the scope and scale of investigation, enabling analyzes of any kind of data in any format, such as DNS transactions or full packet capture data to find malicious activity hidden deep in the masses of an organization's data. IBMWatson Explorer provides a unified view displaying all of security relevant information in a portal-like UI. The information analytics system is built around AQL (Annotated query language), a declarative rule language with a familiar SQL-like syntax. AQL supports the paradigm describing data for data with an optional data governance catalogue for massive volumes of data supporting individual views in addition to the pre-defined Document view that holds the textual and label content. An underlying Role-Based Access Control that data protection rules are strictly enforced within the whole architecture. Security at the document, sub-document and record level is built intoWatson Explorer. When Watson Explorer security is implemented, users cannot see information that they would be prohibited from seeing if they were directly logged into the target system. (author)

  5. Information Asymmetry in Federations

    Directory of Open Access Journals (Sweden)

    Alexander Mikhailovich Libman

    2014-12-01

    Full Text Available The paper investigates the problems of information transmission between levels of government in a federal state. The central government in a federation typically faces serious difficulties while collecting information on economic and political situation in the regions. There are two types of problems: lack of incentives for the regions to accurately collect information and strategic manipulation of information, which are discussed in the paper along with possible solutions. In particular, overcoming information asymmetry would require the development of national parties or informal coalitions of bureaucrats and politicians of the center and of the regions, creating incentives for regional politicians to back the successful functioning of the federal level. Furthermore, the paper discusses the issue of «informal decentralization», which emerges as a result of information asymmetry, and its consequences for the functioning of a federal state, including both advantages and disadvantages. We conclude that under information asymmetry the organization of the federation will inevitably turn into an issue of permanent negotiations and bargaining between the center and the regions, which functions as the information acquisition tool for optimal allocation of authorities in a federation

  6. 75 FR 28777 - Information Collection; Financial Information Security Request Form

    Science.gov (United States)

    2010-05-24

    ... Collection; Financial Information Security Request Form AGENCY: Forest Service, USDA. ACTION: Notice; Request... currently approved information collection; Financial Information Security Request Form. DATES: Comments must... Standard Time, Monday through Friday. SUPPLEMENTARY INFORMATION: Title: Financial Information Security...

  7. Information barriers and authentication

    International Nuclear Information System (INIS)

    MacArthur, D.W.; Wolford, J.K.

    2001-01-01

    Acceptance of nuclear materials into a monitoring regime is complicated if the materials are in classified shapes or have classified composition. An attribute measurement system with an information barrier can be emplo,yed to generate an unclassified display from classified measurements. This information barrier must meet two criteria: (1) classified information cannot be released to the monitoring party, and (2) the monitoring party must be convinced that the unclassified output accurately represents the classified input. Criterion 1 is critical to the host country to protect the classified information. Criterion 2 is critical to the monitoring party and is often termed the 'authentication problem.' Thus, the necessity for authentication of a measurement system with an information barrier stems directly from the description of a useful information barrier. Authentication issues must be continually addressed during the entire development lifecycle of the measurement system as opposed to being applied only after the system is built.

  8. COMPETITIVENESS THROUGH INFORMATION

    Directory of Open Access Journals (Sweden)

    Raluca Daniela RIZEA

    2013-10-01

    Full Text Available Intelligence competitiveness has already started to build its road in the company’s long term strategies. Nonetheless, business executives continue to look for ways to apply information technology strategically to their businesses. Using information managers manage to communicate, to convey their knowledge about markets, competitors, products, services and operations. Even if data and information are all over there are few amounts of managers that realize the importance of them to the success of the business. This article will review competitive forces and competitive information systems strategies for gaining competitive advantages, explain concepts of value chain, value co-opetition (competition and cooperation, and discuss innovation strategy. Co-opetition is a strategy whereby companies cooperate and compete at the same time with their competitors, complementors (i.e. hardware and software businesses, customers, suppliers. The article discuss an important dimension of information system, identifies competitive advantages and enhancing competitive strategies thought information systems.

  9. What constitutes information integrity?

    Directory of Open Access Journals (Sweden)

    S. Flowerday

    2008-01-01

    Full Text Available This research focused on what constitutes information integrity as this is a problem facing companies today. Moreover, information integrity is a pillar of information security and is required in order to have a sound security management programme. However, it is acknowledged that 100% information integrity is not currently achievable due to various limitations and therefore the auditing concept of reasonable assurance is adopted. This is in line with the concept that 100% information security is not achievable and the notion that adequate security is the goal, using appropriate countermeasures. The main contribution of this article is to illustrate the importance of and provide a macro view of what constitutes information integrity. The findings are in harmony with Samuel Johnson's words (1751: 'Integrity without knowledge is weak and useless, and knowledge without integrity is dangerous and dreadful.'

  10. What constitutes information integrity?

    Directory of Open Access Journals (Sweden)

    S. Flowerday

    2007-12-01

    Full Text Available This research focused on what constitutes information integrity as this is a problem facing companies today. Moreover, information integrity is a pillar of information security and is required in order to have a sound security management programme. However, it is acknowledged that 100% information integrity is not currently achievable due to various limitations and therefore the auditing concept of reasonable assurance is adopted. This is in line with the concept that 100% information security is not achievable and the notion that adequate security is the goal, using appropriate countermeasures. The main contribution of this article is to illustrate the importance of and provide a macro view of what constitutes information integrity. The findings are in harmony with Samuel Johnson's words (1751: 'Integrity without knowledge is weak and useless, and knowledge without integrity is dangerous and dreadful.'

  11. Metric adjusted skew information

    DEFF Research Database (Denmark)

    Hansen, Frank

    2008-01-01

    ) that vanishes for observables commuting with the state. We show that the skew information is a convex function on the manifold of states. It also satisfies other requirements, proposed by Wigner and Yanase, for an effective measure-of-information content of a state relative to a conserved observable. We...... establish a connection between the geometrical formulation of quantum statistics as proposed by Chentsov and Morozova and measures of quantum information as introduced by Wigner and Yanase and extended in this article. We show that the set of normalized Morozova-Chentsov functions describing the possible......We extend the concept of Wigner-Yanase-Dyson skew information to something we call "metric adjusted skew information" (of a state with respect to a conserved observable). This "skew information" is intended to be a non-negative quantity bounded by the variance (of an observable in a state...

  12. Information services directory

    International Nuclear Information System (INIS)

    1987-05-01

    This Directory will facilitate dissemination of information. It is a reference document that lists the sources of program information available to the states, Indian Tribes, and the public. Chapter 1 describes current program information sources produced by OCRWM and by DOE's Office of Scientific and Technical Information (OSTI). Chapter 2 provides a directory of OCRWM and DOE technical information, and includes descriptions of computerized data bases and other resources. Chapter 3 is an index of OCRWM Headquarters and Project Office contacts, as well as state and Indian Tribe contacts. Chapter 4 enumerates Congressional Committees and Subcommittees that have jurisdiction over various components of the Civilian Radioactive Waste Management Program, and Chapter 5 lists DOE reading rooms, as well as information offices and the public libraries in affected states that are on one or more of OCRWM's mailing lists

  13. Quantum biological information theory

    CERN Document Server

    Djordjevic, Ivan B

    2016-01-01

    This book is a self-contained, tutorial-based introduction to quantum information theory and quantum biology. It serves as a single-source reference to the topic for researchers in bioengineering, communications engineering, electrical engineering, applied mathematics, biology, computer science, and physics. The book provides all the essential principles of the quantum biological information theory required to describe the quantum information transfer from DNA to proteins, the sources of genetic noise and genetic errors as well as their effects. Integrates quantum information and quantum biology concepts; Assumes only knowledge of basic concepts of vector algebra at undergraduate level; Provides a thorough introduction to basic concepts of quantum information processing, quantum information theory, and quantum biology; Includes in-depth discussion of the quantum biological channel modelling, quantum biological channel capacity calculation, quantum models of aging, quantum models of evolution, quantum models o...

  14. Accident management information needs

    International Nuclear Information System (INIS)

    Hanson, D.J.; Ward, L.W.; Nelson, W.R.; Meyer, O.R.

    1990-04-01

    The tables contained in this Appendix A describe the information needs for a pressurized water reactor (PWR) with a large, dry containment. To identify these information needs, the branch points in the safety objective trees were examined to decide what information is necessary to (a) determine the status of the safety functions in the plant, i.e., whether the safety functions are being adequately maintained within predetermined limits, (b) identify plant behavior (mechanisms) or precursors to this behavior which indicate that a challenge to plant safety is occurring or is imminent, and (c) select strategies that will prevent or mitigate this plant behavior and monitor the implementation and effectiveness of these strategies. The information needs for the challenges to the safety functions are not examined since the summation of the information needs for all mechanisms associated with a challenge comprise the information needs for the challenge itself

  15. Accident management information needs

    Energy Technology Data Exchange (ETDEWEB)

    Hanson, D.J.; Ward, L.W.; Nelson, W.R.; Meyer, O.R. (EG and G Idaho, Inc., Idaho Falls, ID (USA))

    1990-04-01

    The tables contained in this Appendix A describe the information needs for a pressurized water reactor (PWR) with a large, dry containment. To identify these information needs, the branch points in the safety objective trees were examined to decide what information is necessary to (a) determine the status of the safety functions in the plant, i.e., whether the safety functions are being adequately maintained within predetermined limits, (b) identify plant behavior (mechanisms) or precursors to this behavior which indicate that a challenge to plant safety is occurring or is imminent, and (c) select strategies that will prevent or mitigate this plant behavior and monitor the implementation and effectiveness of these strategies. The information needs for the challenges to the safety functions are not examined since the summation of the information needs for all mechanisms associated with a challenge comprise the information needs for the challenge itself.

  16. We inform you, you inform us

    CERN Multimedia

    Association du personnel

    2008-01-01

    Our September information meetings have ended and we thank the many people who came. This will allow us to start an extremely useful dialogue that we will continue with the survey announced at these meetings, which is now available. We invite all CERN staff members to reply to this questionnaire to enable us to have an accurate picture of your expectations and wishes with respect to the evolution of social and employment policies.

  17. Information, Technology, and Information Worker Productivity

    OpenAIRE

    Aral, Sinan; Brynjolfsson, Erik; Van Alstyne, Marshall

    2009-01-01

    We econometrically evaluate information worker productivity at a midsize executive recruiting firm and assess whether the knowledge that workers accessed through their electronic communication networks enabled them to multitask more productively. We estimate dynamic panel data models of multitasking, knowledge networks, and productivity using several types of micro-level data: (a) direct observation of more than 125,000 email messages over a period of 10 months; (b) detailed accounting data o...

  18. Medical Information Security

    OpenAIRE

    William C. Figg, Ph.D.; Hwee Joo Kam, M.S.

    2011-01-01

    Modern medicine is facing a complex environment, not from medical technology but rather government regulations and information vulnerability. HIPPA is the government’s attempt to protect patient’s information yet this only addresses traditional record handling. The main threat is from the evolving security issues. Many medical offices and facilities have multiple areas of information security concerns. Physical security is often weak, office personnel are not always aware of security needs an...

  19. Formalized Informal Learning

    DEFF Research Database (Denmark)

    Levinsen, Karin Tweddell; Sørensen, Birgitte Holm

    2013-01-01

    are examined and the relation between network society competences, learners’ informal learning strategies and ICT in formalized school settings over time is studied. The authors find that aspects of ICT like multimodality, intuitive interaction design and instant feedback invites an informal bricoleur approach....... When integrated into certain designs for teaching and learning, this allows for Formalized Informal Learning and support is found for network society competences building....

  20. Quality of Information

    OpenAIRE

    Christensen, Leif

    2016-01-01

    Accounting and auditing is closely related to the quality of data. Two important elements supporting the quality of information are internal controls and materiality. Inspired by Simons (1994), these elements can be considered “basic building blocks”. Internal controls are perhaps the most important element, as they ensure that information used for management purposes has the required quality (Kinney, 2000). This information can be used as a basis for preparing the external ...

  1. Design information verification

    International Nuclear Information System (INIS)

    Johnson, Shirley

    2001-01-01

    The paper provides the bases to complete a Design Information Questionnaire (DIQ) for a research reactor. The IAEA requirements for provision of design information for nuclear facility is described. The role of the provided information for the development of the safeguards approach and for planning of the IAEA's general inspection program for a specific facility is emphasized. Content and preparation of the IAEA DIQ by the State is presented

  2. Information security fundamentals

    CERN Document Server

    Peltier, Thomas R

    2013-01-01

    Developing an information security program that adheres to the principle of security as a business enabler must be the first step in an enterprise's effort to build an effective security program. Following in the footsteps of its bestselling predecessor, Information Security Fundamentals, Second Edition provides information security professionals with a clear understanding of the fundamentals of security required to address the range of issues they will experience in the field.The book examines the elements of computer security, employee roles and r

  3. Management Information Systems

    OpenAIRE

    Furduescu Bogdan-Alexandru

    2017-01-01

    Technology is the science that studies processes, methods and operations run or applied onto raw materials, matters or data, in order to obtain a certain product. Information is the material signal able to launch a material reaction of a dynamic auto-tuning system for which the system is conditioned and finalized. Information Technology is the technology needed for handling (procuring, processing, storing converting and transmitting) information, in particular, with the use of computers [Long...

  4. Management Information Systems Research.

    Science.gov (United States)

    Research on management information systems is illusive in many respects. Part of the basic research problem in MIS stems from the absence of standard...decision making. But the transition from these results to the realization of ’satisfactory’ management information systems remains difficult indeed. The...paper discusses several aspects of research on management information systems and reviews a selection of efforts that appear significant for future progress. (Author)

  5. 2001 Industry Studies: Information

    Science.gov (United States)

    2001-01-01

    increasingly demand communications, computers, and software for use in the Internet , intranets, and extranets. Information technology (IT) - enabled...As the number of Internet users increases, so does the demand for the rapid deployment of information and telecommunication technologies . The key...proliferation has become uncontrollable. Only then will the US maintain the lead in the IT market . 13 ESSAYS ON MAJOR ISSUES ISSUE: THE INFORMATION TECHNOLOGY

  6. Framing Information Literacy

    OpenAIRE

    Anneke Dirkx

    2016-01-01

    In 2000 the Association of College & Research Libraries (ACRL) published the Standards for Information Literacy. After 15 years these standards were in desperate need of revision. Instead of releasing a revised edition of the Standards, in 2015 ACRL presented a completely new vision on information literacy in higher education. In this keynote we will explore the new ACRL Framework for Information Literacy in all its glory. We will compare it to the old standards. Is this new American Fram...

  7. IAEA safeguards information system

    International Nuclear Information System (INIS)

    Nardi, J.

    1984-01-01

    The basic concepts, structure, and operation of the Agency Safeguards Information System is discussed with respect to its role in accomplishing the overall objectives of safeguards. The basis and purposes of the Agency's information system, the structure and flow of information within the Agency's system, the relationship of the components is the Agency system, the requirements of Member States in respect of their reporting to the Agency, and the relationship of accounting data vis-a-vis facility and inspection data are described

  8. Information Needs/Relevance

    OpenAIRE

    Wildemuth, Barbara M.

    2009-01-01

    A user's interaction with a DL is often initiated as the result of the user experiencing an information need of some kind. Aspects of that experience and how it might affect the user's interactions with the DL are discussed in this module. In addition, users continuously make decisions about and evaluations of the materials retrieved from a DL, relative to their information needs. Relevance judgments, and their relationship to the user's information needs, are discussed in this module. Draft

  9. HOPE information system review

    Science.gov (United States)

    Suzuki, Yoshiaki; Nishiyama, Kenji; Ono, Shuuji; Fukuda, Kouin

    1992-08-01

    An overview of the review conducted on H-2 Orbiting Plane (HOPE) is presented. A prototype model was constructed by inputting various technical information proposed by related laboratories. Especially operation flow which enables understanding of correlation between various analysis items, judgement criteria, technical data, and interfaces with others was constructed. Technical information data base and retrieval systems were studied. A Macintosh personal computer was selected for information shaping because of its excellent function, performance, operability, and software completeness.

  10. Geometric theory of information

    CERN Document Server

    2014-01-01

    This book brings together geometric tools and their applications for Information analysis. It collects current and many uses of in the interdisciplinary fields of Information Geometry Manifolds in Advanced Signal, Image & Video Processing, Complex Data Modeling and Analysis, Information Ranking and Retrieval, Coding, Cognitive Systems, Optimal Control, Statistics on Manifolds, Machine Learning, Speech/sound recognition, and natural language treatment which are also substantially relevant for the industry.

  11. Future of information architecture

    CERN Document Server

    Baofu, Peter

    2008-01-01

    The Future of Information Architecture examines issues surrounding why information is processed, stored and applied in the way that it has, since time immemorial. Contrary to the conventional wisdom held by many scholars in human history, the recurrent debate on the explanation of the most basic categories of information (eg space, time causation, quality, quantity) has been misconstrued, to the effect that there exists some deeper categories and principles behind these categories of information - with enormous implications for our understanding of reality in general. To understand this, the b

  12. Teaching information seeking

    Directory of Open Access Journals (Sweden)

    Louise Limberg

    2006-01-01

    Full Text Available Introduction. The article argues for a closer association between information seeking research and the practices of teaching information seeking. Findings are presented from a research project on information seeking, didactics and learning (IDOL investigating librarians' and teachers' experiences of teaching information seeking. Method. Thirteen teachers and five librarians, teaching 12-19 year-old students in three schools, participated. Forty-five interviews were conducted over a period of three years. Analysis. The IDOL project adopted a phenomenographic approach with the purpose of describing patterns of variation in experiences. The findings were also analysed by way of relating them to four competing approaches to the mediation of information literacy. Results. A gap was identified between experiences of teaching content that focused on sources and order, and experiences of assessment criteria applied to students' work that focused on the importance of correct facts and the analysis of information. These findings indicate a highly restricted range of teaching contents when compared with the four theoretical approaches to the mediation of information literacy. Conclusion. Teaching information seeking might be enhanced by a wider repertoire of contents reflecting more varied theoretical understanding developed in information seeking research, particularly as regards the importance of content and context related to user perspectives.

  13. Brownfields Site Information

    Data.gov (United States)

    U.S. Environmental Protection Agency — This asset contains all Brownfield facility data. It includes all information necessary to track Brownfields grant recipients' environmental progress at Brownfield...

  14. Credential Application Awaiting Information

    Data.gov (United States)

    Department of Homeland Security — When a Credential application or required documentation is incomplete, an Awaiting Information letter is issued. The application process cannot continue until all...

  15. Information management for clinicians.

    Science.gov (United States)

    Mehta, Neil B; Martin, Stephen A; Maypole, Jack; Andrews, Rebecca

    2016-08-01

    Clinicians are bombarded with information daily by social media, mainstream television news, e-mail, and print and online reports. They usually do not have much control over these information streams and thus are passive recipients, which means they get more noise than signal. Accessing, absorbing, organizing, storing, and retrieving useful medical information can improve patient care. The authors outline how to create a personalized stream of relevant information that can be scanned regularly and saved so that it is readily accessible. Copyright © 2016 Cleveland Clinic.

  16. Airports Geographic Information System -

    Data.gov (United States)

    Department of Transportation — The Airports Geographic Information System maintains the airport and aeronautical data required to meet the demands of the Next Generation National Airspace System....

  17. Quantification of informed opinion

    International Nuclear Information System (INIS)

    Rasmuson, D.M.

    1985-01-01

    The objective of this session, Quantification of Informed Opinion, is to provide the statistician with a better understanding of this important area. The NRC uses informed opinion, sometimes called engineering judgment or subjective judgment, in many areas. Sometimes informed opinion is the only source of information that exists, especially in phenomenological areas, such as steam explosions, where experiments are costly and phenomena are very difficult to measure. There are many degrees of informed opinion. These vary from the weatherman who makes predictions concerning relatively high probability events with a large data base to the phenomenological expert who must use his intuition tempered with basic knowledge and little or no measured data to predict the behavior of events with a low probability of occurrence. The first paper in this session provides the reader with an overview of the subject area. The second paper provides some aspects that must be considered in the collection of informed opinion to improve the quality of the information. The final paper contains an example of the use of informed opinion in the area of seismic hazard characterization. These papers should be useful to researchers and statisticians who need to collect and use informed opinion in their work

  18. Advanced information society (10)

    Science.gov (United States)

    Masuyama, Keiichi

    Informationalization in Japan has spread among various fields of industrial and social life in wide and depth by drastic advancement in technology and networking. Looking at the change in industrial structure as well as international trend in information the Japanese Government regards the role of information and communication technology as infrastructure to be important, and is under the way of constructing various measures with ministries and agencies concerned with them. This paper describes how administrative agencies involved in information and communication such as Ministry of Postal Services, Ministry of International Trade and Industry cope with informationalization, and mentions future direction in information policies.

  19. Carbon Monoxide Information Center

    Medline Plus

    Full Text Available ... Regulations, Laws & Standards Research & Statistics Business & Manufacturing Small Business ... Performances & Finance Open Government Freedom of Information (FOIA) Inspector General ...

  20. Introduction to information science

    CERN Document Server

    Bawden, David

    2012-01-01

    This landmark textbook takes a whole subject approach to Information Science as a discipline. Introduced by leading international scholars and offering a global perspective on the discipline, this is designed to be the standard text for students worldwide. The authors' expert narrative guides you through each of the essential building blocks of information science offering a concise introduction and expertly chosen further reading and resources.Critical topics covered include:foundations: concepts, theories and historical perspectivesorganising and retrieving Information information behaviour,

  1. Information security management handbook

    CERN Document Server

    Tipton, Harold F

    2003-01-01

    Since 1993, the Information Security Management Handbook has served not only as an everyday reference for information security practitioners but also as an important document for conducting the intense review necessary to prepare for the Certified Information System Security Professional (CISSP) examination. Now completely revised and updated and in its fifth edition, the handbook maps the ten domains of the Information Security Common Body of Knowledge and provides a complete understanding of all the items in it. This is a ...must have... book, both for preparing for the CISSP exam and as a c

  2. Health Information Systems.

    Science.gov (United States)

    Sirintrapun, S Joseph; Artz, David R

    2015-06-01

    This article provides surgical pathologists an overview of health information systems (HISs): what they are, what they do, and how such systems relate to the practice of surgical pathology. Much of this article is dedicated to the electronic medical record. Information, in how it is captured, transmitted, and conveyed, drives the effectiveness of such electronic medical record functionalities. So critical is information from pathology in integrated clinical care that surgical pathologists are becoming gatekeepers of not only tissue but also information. Better understanding of HISs can empower surgical pathologists to become stakeholders who have an impact on the future direction of quality integrated clinical care. Copyright © 2015 Elsevier Inc. All rights reserved.

  3. Quantum information processing

    National Research Council Canada - National Science Library

    Leuchs, Gerd; Beth, Thomas

    2003-01-01

    ... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1.5 SimulationofHamiltonians... References... 1 1 1 3 5 8 10 2 Quantum Information Processing and Error Correction with Jump Codes (G. Alber, M. Mussinger...

  4. EDIS Investigation Filing Information

    Data.gov (United States)

    US International Trade Commission — This dataset contains investigation, document and attachment metadata from the USITC's Electronic Document Information System (EDIS), as well as access to attached...

  5. Car monitoring information systems

    Directory of Open Access Journals (Sweden)

    Alica KALAŠOVÁ

    2008-01-01

    Full Text Available The objective of this contribution is to characterize alternatives of information systems used for managing, processing and evaluation of information related to company vehicles. Especially we focus on logging, transferring and processing of on-road vehicle movement information in inland and international transportation. This segment of company information system has to monitor the car movement – actively or passively – according to demand of the company and after the processing it has to evaluate and give the complex monitoring of a situation of all the company vehicles to the controller.

  6. Information, conservation and retrieval

    Energy Technology Data Exchange (ETDEWEB)

    Eng, T [Swedish Nuclear Fuel and Waste Management Co., Stockholm (Sweden); Norberg, E [National Swedish Archives, Stockholm (Sweden); Torbacke, J [Stockholm Univ. (Sweden). Dept. of History; Jensen, M [Swedish Radiation Protection Inst., Stockholm (Sweden)

    1996-12-01

    The seminar took place on the Swedish ship for transportation of radioactive wastes, M/S Sigyn, which at summer time is used for exhibitions. The seminar treated items related to general information needs in society and questions related to radioactive waste, i.e. how knowledge about a waste repository should be passed on to future generations. Three contributions are contained in the report from the seminar and are indexed separately: `Active preservation - otherwise no achieves`; `The conservation and dissemination of information - A democratic issue`; and, `Conservation and retrieval of information - Elements of a strategy to inform future societies about nuclear waste repositories`.

  7. Sustainability of scholarly information

    CERN Document Server

    Chowdhury, G G

    2015-01-01

    Professor Gobinda Chowdhury BSc Hons, MSc, PhD, FCLIP is Professor in Information Science at iSchool@northumbria, and Head of the Department of Mathematics and Information Sciences at Northumbria University. Before joining Northumbria University he was a Professor and Director of the Centre for Information and Knowledge Management at the University of Technology Sydney, Australia. For over 25 years he has worked as an academic and researcher in information science in different parts of the world including Asia, Africa, Europe and Australia. For the past few years he has been actively involved

  8. Integrated Information Management (IIM)

    National Research Council Canada - National Science Library

    McIlvain, Jason

    2007-01-01

    Information Technology is the core capability required to align our resources and increase our effectiveness on the battlefield by integrating and coordinating our preventative measures and responses...

  9. Information, conservation and retrieval

    International Nuclear Information System (INIS)

    Eng, T.; Norberg, E.; Torbacke, J.

    1996-12-01

    The seminar took place on the Swedish ship for transportation of radioactive wastes, M/S Sigyn, which at summer time is used for exhibitions. The seminar treated items related to general information needs in society and questions related to radioactive waste, i.e. how knowledge about a waste repository should be passed on to future generations. Three contributions are contained in the report from the seminar and are indexed separately: 'Active preservation - otherwise no achieves'; 'The conservation and dissemination of information - A democratic issue'; and, 'Conservation and retrieval of information - Elements of a strategy to inform future societies about nuclear waste repositories'

  10. Informação ao paciente com câncer: o olhar do oncologista Information to the patient with cancer: the oncologist's view

    Directory of Open Access Journals (Sweden)

    Paula Danielle Santa Maria de Albuquerque

    2011-04-01

    Full Text Available OBJETIVO: Identificar o que os médicos-oncologistas informam aos seus pacientes, verificar o que levam em consideração no processo de informar, e averiguar a quem fornecem a informação. MÉTODOS: Os sujeitos da pesquisa foram oncologistas, recrutados dentre aqueles inscritos na Sociedade Brasileira de Oncologia Clínica (SBOC. Foi enviado para a sociedade, via correio, todo o material a ser encaminhado aos oncologistas. Os envelopes, selados previamente, continham: formulário para coleta de dados e informações para o preenchimento e termo de consentimento livre e esclarecido (TCLE. Os dados obtidos foram tratados estatisticamente obedecendo a um intervalo de confiança de 95%. RESULTADOS: Foram encaminhadas 876 correspondências (total de médicos associados à SBOC e obteve-se um índice de 16,55% de resposta. Quanto ao que informam, 81% dos médicos responderam que informavam o diagnóstico, o tratamento e o prognóstico aos seus pacientes; entretanto, 73% relataram que, em grande parte dos casos, o paciente já tem conhecimento da sua doença. Por sua vez, a informação é fornecida ao paciente e à sua família por 81% dos médicos. Dentre os aspectos relevantes no processo de informar, destaca-se que o gênero do paciente pouco influencia na informação para 95% dos médicos. CONCLUSÃO: Diante dos resultados apresentados, conclui-se que na população estudada existe a preocupação em informar adequando-se ao perfil do paciente. Percebe-se, ainda, que os oncologistas tentam prover o paciente do que lhe é de direito - a verdade -, embora muitas vezes recorram à família para auxiliar no fornecimento das informações.OBJECTIVE: To identify what information is provided to the patients by oncologists, assess what they take into account in the process of informing the patient, and to ascertain whom the information is provided to. METHODS: The study subjects were oncologists recruited among those registered at the Brazilian Society

  11. Fundamentals of quantum information

    International Nuclear Information System (INIS)

    Zeilinger, A.

    1998-01-01

    The fact that information is physical means that the laws of quantum mechanics can be used to process and transmit it in ways that are not possible with existing systems. Ever since its invention in the 1920s, quantum physics has given rise to countless discussions about its meaning and about how to interpret the theory correctly. These discussions focus on issues like the Einstein-Podolsky-Rosen paradox, quantum non-locality and the role of measurement in quantum physics. In recent years, however, research into the very foundations of quantum mechanics has also led to a new field quantum information technology. The use of quantum physics could revolutionize the way we communicate and process information. The important new observation is that information is not independent of the physical laws used to store and processes it (see Landauer in further reading). Although modern computers rely on quantum mechanics to operate, the information itself is still encoded classically. A new approach is to treat information as a quantum concept and to ask what new insights can be gained by encoding this information in individual quantum systems. In other words, what happens when both the transmission and processing of information are governed by quantum laws? (UK)

  12. Carbon Monoxide Information Center

    Medline Plus

    Full Text Available ... main content Languages 简体中文 English Bahasa Indonesia 한국어 Español ภาษาไทย Tiếng Việt Text Size: Decrease Font Increase ... Monoxide Information Center Carbon Monoxide Information Center En Español The Invisible Killer Carbon monoxide, also known as ...

  13. Science and information theory

    CERN Document Server

    Brillouin, Léon

    1962-01-01

    A classic source for exploring the connections between information theory and physics, this text is geared toward upper-level undergraduates and graduate students. The author, a giant of 20th-century mathematics, applies the principles of information theory to a variety of issues, including Maxwell's demon, thermodynamics, and measurement problems. 1962 edition.

  14. Carbon Monoxide Information Center

    Medline Plus

    Full Text Available ... Information (FOIA) Inspector General No Fear Act Data USA.gov Report an Unsafe Product Contact Us: 800- ... Budget & Performance Open Government Freedom of Information (FOIA) USA.gov CPSC.gov is the U.S. government's official ...

  15. information manger-2012-editedx

    African Journals Online (AJOL)

    Library _info_Sc_ 1

    much as possible to exploit the benefits brought by information and communication technologies (ICTs) as an alternative to its services and for easy access, retrieval and dissemination of information to it users. Introduction. The Northern Nigerian area has been one of the earliest regions of West Africa with a literary tradition ...

  16. Archival Information Management System.

    Science.gov (United States)

    1995-02-01

    management system named Archival Information Management System (AIMS), designed to meet the audit trail requirement for studies completed under the...are to be archived to the extent that future reproducibility and interrogation of results will exist. This report presents a prototype information

  17. Anthropology and nuclear information

    International Nuclear Information System (INIS)

    Van Nuffelen, D.

    1994-01-01

    In this article is sketched a paradigm which permits to envisage nuclear information as an anthropologic problem. The author modelizes public information by a general theory of exchange. For him the most urgent problem is to refounding the circulation between the different components of social system. 3 figs,. 2 tabs,. 12 refs

  18. Credit Market Information Feedback

    OpenAIRE

    Balasubramanyan, Lakshmi; Craig, Ben R.; Thomson, James B.; Zaman, Saeed

    2015-01-01

    We examine how a combination of credit market and asset quality information can jointly be used in assessing bank franchise value. We find that expectations of future credit demand and future asset quality explain contemporaneous bank franchise value, indicative of the feedback in credit market information and its consequent impact on bank franchise value.

  19. Investigating Music Information Objects

    Science.gov (United States)

    Weissenberger, Lynnsey K.

    2016-01-01

    This dissertation, titled "Investigating Music Information Objects," is a study of the nature, description, representations, and ideas related to music information objects (MIOs). This research study investigates how music practitioners from various traditions describe and conceptualize MIOs, using a theoretical framework to classify…

  20. Evolution of information systems

    DEFF Research Database (Denmark)

    Kristensen, Jan

    2000-01-01

    This article offers a dynamic view of continuously changes in a specific informational system illustrated through a case study in a small network company. Central aspects of the evolutionary process will be identified and framed in relation to the informational system change. It will be argued th...

  1. Hybrid quantum information processing

    Energy Technology Data Exchange (ETDEWEB)

    Furusawa, Akira [Department of Applied Physics, School of Engineering, The University of Tokyo (Japan)

    2014-12-04

    I will briefly explain the definition and advantage of hybrid quantum information processing, which is hybridization of qubit and continuous-variable technologies. The final goal would be realization of universal gate sets both for qubit and continuous-variable quantum information processing with the hybrid technologies. For that purpose, qubit teleportation with a continuousvariable teleporter is one of the most important ingredients.

  2. Summary information report

    International Nuclear Information System (INIS)

    1982-07-01

    The Summary Information Report (SIR) provides summary data concerning NRC and its licensees for general use by the Chairman, other Commissioners and Commission staff offices, the Executive Director for Operations, and the Office Directors. SIR is published quarterly by the Management Information Branch (49-27834) of the Office of Resource Management

  3. Lean information management

    NARCIS (Netherlands)

    Hammer, D.K.

    1997-01-01

    The concept of a Lean Enterprise has proven to be extremely valuable for making companies fit for today's competitive business environment. Lean Information Management denotes the type of information management that is appropriate for such all organization. According to the paradigm of a Lean

  4. Makerspaces in Informal Settings

    Science.gov (United States)

    Brown, Ryan A.; Antink-Meyer, Allison

    2017-01-01

    The maker movement, with its focus on-hands on learning through creating with familiar materials, has seen growth in both formal and informal learning spaces. This article examines three informal learning spaces that have redesigned their space (or a portion of it) to accommodate several tenets of the maker movement and in various ways have become…

  5. Information security management principles

    CERN Document Server

    Taylor, Andy; Finch, Amanda; Sutton, David; Taylor, Andy

    2013-01-01

    In today's technology-driven environment, there is an ever-increasing demand for information delivery. A compromise has to be struck between security and availability. This book is a pragmatic guide to information assurance for both business professionals and technical experts. This second edition includes the security of cloud-based resources.

  6. Carbon Monoxide Information Center

    Medline Plus

    Full Text Available ... United States government. Website Feedback Connect with Us: Facebook Instagram YouTube Twitter Blog SlideShare GooglePlus Flickr Report an Unsafe Product Subscribe to CPSC News and Information Sitemap RSS E-mail Accessibility Privacy Policy Budget & Performance Open Government Freedom of Information ( ...

  7. Information or communication

    DEFF Research Database (Denmark)

    Dahms, Mona-Lisa

    2004-01-01

    The paper describes the development in Tanzania, in terms of information and communication technologies and how these developments have influenced people's daily life.......The paper describes the development in Tanzania, in terms of information and communication technologies and how these developments have influenced people's daily life....

  8. Slavery and information

    NARCIS (Netherlands)

    Dari-Mattiacci, G.

    2013-01-01

    This article shows how asymmetric information shaped slavery by determining the likelihood of manumission. A theoretical model explains the need to offer positive incentives to slaves working in occupations characterized by a high degree of asymmetric information. As a result, masters freed (and,

  9. Hybrid wars’ information component

    Directory of Open Access Journals (Sweden)

    T. A. Nevskaya

    2015-01-01

    Full Text Available The war of the new generation - hybrid war, the information component which is directed not so much on the direct destruction of the enemy, how to achieve the goals without warfare. Fighting in the information field is no less important than immediate military action.

  10. Constructor theory of information

    Science.gov (United States)

    Deutsch, David; Marletto, Chiara

    2015-01-01

    We propose a theory of information expressed solely in terms of which transformations of physical systems are possible and which are impossible—i.e. in constructor-theoretic terms. It includes conjectured, exact laws of physics expressing the regularities that allow information to be physically instantiated. Although these laws are directly about information, independently of the details of particular physical instantiations, information is not regarded as an a priori mathematical or logical concept, but as something whose nature and properties are determined by the laws of physics alone. This theory solves a problem at the foundations of existing information theory, namely that information and distinguishability are each defined in terms of the other. It also explains the relationship between classical and quantum information, and reveals the single, constructor-theoretic property underlying the most distinctive phenomena associated with the latter, including the lack of in-principle distinguishability of some states, the impossibility of cloning, the existence of pairs of variables that cannot simultaneously have sharp values, the fact that measurement processes can be both deterministic and unpredictable, the irreducible perturbation caused by measurement, and locally inaccessible information (as in entangled systems). PMID:25663803

  11. Post-socialist Informalities

    DEFF Research Database (Denmark)

    to understand and explain informality, while also debating its relationship with the market and society. The authors seek to explain informality beyond a mere monetaristic/economistic approach, rediscovering its interconnection with social phenomena to propose a more holistic interpretation of the meaning...

  12. Information extraction system

    Science.gov (United States)

    Lemmond, Tracy D; Hanley, William G; Guensche, Joseph Wendell; Perry, Nathan C; Nitao, John J; Kidwell, Paul Brandon; Boakye, Kofi Agyeman; Glaser, Ron E; Prenger, Ryan James

    2014-05-13

    An information extraction system and methods of operating the system are provided. In particular, an information extraction system for performing meta-extraction of named entities of people, organizations, and locations as well as relationships and events from text documents are described herein.

  13. Marketing Information Literacy

    Science.gov (United States)

    Seale, Maura

    2013-01-01

    In 2012, more than a decade after the original Association of College and Research Libraries (ACRL) Information Literacy Competency Standards for Higher Education (hereafter the Standards) were institutionalized as the goal of academic library instruction, the Information Literacy Competency Standards Review Task Force convened by ACRL recommended…

  14. Institutionalizing Information Literacy

    Science.gov (United States)

    Weiner, Sharon A.

    2012-01-01

    There is increasing recognition that information literacy is essential for individual and community empowerment, workforce readiness, and global competitiveness. However, there is a history of difficulty in integrating information literacy with the postsecondary educational process. This paper posits that a greater understanding of the…

  15. Public information strategies

    International Nuclear Information System (INIS)

    Waldahl, R.

    1995-01-01

    The Chernobyl accident in 1986 uncovered serious information problems in many Western countries, and started a debate on crisis communication and information strategies in relation to radiation danger in society. The information problem focuses on four main perspectives. The first is related to information as a persuasion process in which an efficient strategy would influence both the public's knowledge of radiation danger, their attitude towards it and their behaviour. The second perspective calls attention to the importance of the different elements of the information process. How important are different characteristics of the information source; the message itself, and the receiver? The third perspective concentrates on different types of information. What is this issue all about, why is the situation as it is, and how should people behave to protect themselves? The fourth perspective points to the various phases of a crisis. The information needed is obviously not the same in the period before a crisis emerges when no one knows what is going to happen, in the warning period when one knows that something may happen, and during the crisis itself. (Author)

  16. The nature of information

    Science.gov (United States)

    Tpudlik

    2015-11-01

    In reply to Mark Buchanan's review of César Hidalgo's book How Information Grows (“The wealth of nations”, October pp40-41, http://ow.ly/SlqN3), in which Hidalgo argues that we need an “information-centric” view of economic growth.

  17. ISRIC - World Soil Information

    NARCIS (Netherlands)

    Dent, D.L.

    2006-01-01

    ISRICWorld Soil Information is an independent foundation, funded by the Netherlands Government with a mandate to increase knowledge of the land, its soils in particular, and to support the sustainable use of land resources; in short, to help people understand soils. Its aims are to -Inform and

  18. The Information Age?

    Science.gov (United States)

    MacVicar, Margaret L. A.

    1985-01-01

    The author examines the concept of information and how it relates to our future. She discusses the various waves of information about education: the decay of technology and the raid on educational institutions for brainpower made by business and industry, foreign competition, and the quality of education. (CT)

  19. Information Retrieval in Physics.

    Science.gov (United States)

    Herschman, Arthur

    Discussed in this paper are the information problems in physics and the current program of the American Institute of Physics (AIP) being conducted in an attempt to develop an information retrieval system. The seriousness of the need is described by means of graphs indicating the exponential rise in the number of physics publications in the last…

  20. INFORMATION AND COMMUNICATION

    African Journals Online (AJOL)

    USER

    legislators have to be ICT compliant so that they can utilize the services of their libraries and information centres to the fullest capacity. Introduction ... engagement in collaborative efforts with other libraries and information centres within ... economic, political and other civic activities that takes place in the country for which the.

  1. Information and Rural Development.

    Science.gov (United States)

    Storm, Bonnie L.

    1982-01-01

    Outlines approaches taken to development in lesser developed countries in the past, discusses the importance of appropriate technology and human development, and summarizes the information needs of the rural poor in developing nations. Information dissemination programs using video- and audiotape technology in Bangladesh, Guatemala, and Peru are…

  2. A Mine of Information.

    Science.gov (United States)

    Williams, Lisa B.

    1986-01-01

    Business researchers and marketers find certain databases useful for finding information on investments, competitors, products, and markets. Colleges can use these same databases to get background on corporate prospects. The largest data source available, DIALOG Information Services and some other databases are described. (MLW)

  3. Strengthening Health Information Services

    Science.gov (United States)

    Haro, A. S.

    1977-01-01

    Discusses the need to apply modern scientific management to health administration in order to effectively manage programs utilizing increased preventive and curative capabilities. The value of having maximum information in order to make decisions, and problems of determining information content are reviewed. For journal availability, see SO 506…

  4. Medical Information Management System

    Science.gov (United States)

    Alterescu, S.; Hipkins, K. R.; Friedman, C. A.

    1979-01-01

    On-line interactive information processing system easily and rapidly handles all aspects of data management related to patient care. General purpose system is flexible enough to be applied to other data management situations found in areas such as occupational safety data, judicial information, or personnel records.

  5. Personal Information Request Form

    International Development Research Centre (IDRC) Digital Library (Canada)

    PC Forms Inc. 834-4048

    To apply for information under the Privacy Act, complete this form or a written request mentioning the Act. Describe the information being sought and provide any relevant details necessary to help the. International Development Research Centre. (IDRC) find it. If you require assistance, refer to. Info Source (Sources of ...

  6. Information. Mapping the money.

    Science.gov (United States)

    Cowper, Andy

    2006-03-16

    Dr Foster Intelligence aims to improve the use and accessibility of information to offer people more control over their care. It will also provide management with the information required to make effective business decisions. The new service will be 'taking advantage of private-sector expertise for public-sector advantage.

  7. Air System Information Management

    Science.gov (United States)

    Filman, Robert E.

    2004-01-01

    I flew to Washington last week, a trip rich in distributed information management. Buying tickets, at the gate, in flight, landing and at the baggage claim, myriad messages about my reservation, the weather, our flight plans, gates, bags and so forth flew among a variety of travel agency, airline and Federal Aviation Administration (FAA) computers and personnel. By and large, each kind of information ran on a particular application, often specialized to own data formats and communications network. I went to Washington to attend an FAA meeting on System-Wide Information Management (SWIM) for the National Airspace System (NAS) (http://www.nasarchitecture.faa.gov/Tutorials/NAS101.cfm). NAS (and its information infrastructure, SWIM) is an attempt to bring greater regularity, efficiency and uniformity to the collection of stovepipe applications now used to manage air traffic. Current systems hold information about flight plans, flight trajectories, weather, air turbulence, current and forecast weather, radar summaries, hazardous condition warnings, airport and airspace capacity constraints, temporary flight restrictions, and so forth. Information moving among these stovepipe systems is usually mediated by people (for example, air traffic controllers) or single-purpose applications. People, whose intelligence is critical for difficult tasks and unusual circumstances, are not as efficient as computers for tasks that can be automated. Better information sharing can lead to higher system capacity, more efficient utilization and safer operations. Better information sharing through greater automation is possible though not necessarily easy.

  8. Intelligent medical information filtering.

    Science.gov (United States)

    Quintana, Y

    1998-01-01

    This paper describes an intelligent information filtering system to assist users to be notified of updates to new and relevant medical information. Among the major problems users face is the large volume of medical information that is generated each day, and the need to filter and retrieve relevant information. The Internet has dramatically increased the amount of electronically accessible medical information and reduced the cost and time needed to publish. The opportunity of the Internet for the medical profession and consumers is to have more information to make decisions and this could potentially lead to better medical decisions and outcomes. However, without the assistance from professional medical librarians, retrieving new and relevant information from databases and the Internet remains a challenge. Many physicians do not have access to the services of a medical librarian. Most physicians indicate on surveys that they do not prefer to retrieve the literature themselves, or visit libraries because of the lack of recent materials, poor organisation and indexing of materials, lack of appropriate and available material, and lack of time. The information filtering system described in this paper records the online web browsing behaviour of each user and creates a user profile of the index terms found on the web pages visited by the user. A relevance-ranking algorithm then matches the user profiles to the index terms of new health care web pages that are added each day. The system creates customised summaries of new information for each user. A user can then connect to the web site to read the new information. Relevance feedback buttons on each page ask the user to rate the usefulness of the page to their immediate information needs. Errors in relevance ranking are reduced in this system by having both the user profile and medical information represented in the same representation language using a controlled vocabulary. This system also updates the user profiles

  9. Canonical Information Analysis

    DEFF Research Database (Denmark)

    Vestergaard, Jacob Schack; Nielsen, Allan Aasbjerg

    2015-01-01

    is replaced by the information theoretical, entropy based measure mutual information, which is a much more general measure of association. We make canonical information analysis feasible for large sample problems, including for example multispectral images, due to the use of a fast kernel density estimator......Canonical correlation analysis is an established multivariate statistical method in which correlation between linear combinations of multivariate sets of variables is maximized. In canonical information analysis introduced here, linear correlation as a measure of association between variables...... for entropy estimation. Canonical information analysis is applied successfully to (1) simple simulated data to illustrate the basic idea and evaluate performance, (2) fusion of weather radar and optical geostationary satellite data in a situation with heavy precipitation, and (3) change detection in optical...

  10. Energy Information Directory 1991

    International Nuclear Information System (INIS)

    1992-01-01

    The National Energy Information Center (NEIC), as part of its mission, provides energy information and referral assistance to Federal, State, and local governments, the academic community, business and industrial organizations, and the general public. The two principal functions related to this task are (1) operating a general access telephone line, and (2) responding to energy-related correspondence addressed to the Energy Information Administration (EIA). The Energy Information Directory was developed to assist the NEIC staff as well as other Department of Energy (DOE) staff, in directing inquires to the proper offices within DOE, other Federal agencies, or energy-related trade associations. The Directory is a list of most Government offices and trade associations that are involved in energy matters. It does not include those DOE offices which do not deal with the public or public information

  11. Micro Information Systems

    DEFF Research Database (Denmark)

    Ulslev Pedersen, Rasmus; Kühn Pedersen, Mogens

    2014-01-01

    such as medical and manufacturing. These new sensor applications have implications for information systems (IS) and, the authors visualize this new class of information systems as fractals growing from an established class of systems; namely that of information systems (IS). The identified applications...... and implications are used as an empirical basis for creating a model for these small new information systems. Such sensor systems are called embedded systems in the technical sciences, and the authors want to couple it with general IS. They call the merger of these two important research areas (IS and embedded...... systems) for micro information systems (micro-IS). It is intended as a new research field within IS research. An initial framework model is established, which seeks to capture both the possibilities and constraints of this new paradigm, while looking simultaneously at the fundamental IS and ICT aspects...

  12. Training and information

    International Nuclear Information System (INIS)

    Anon.

    1977-01-01

    The Training and Information Division provides centralized direction and coordination for the training and information activities of the Center for Energy and Environment Research (formerly Puerto Rico Nuclear Center). The Division Head serves as Educational Officer, Technical Information Officer, and Public Information Officer. Training responsibilities include registering students; maintaining centralized records on training activities; preparing reports for ERDA; scheduling the utilization of training facilities; providing audiovisual equipment; assisting in the preparation of courses, seminars, symposia, and meetings; administering fellowship programs; and providing personal assistance to students in matters such as housing and immigration. The Division Head represents the Director on the Admissions Committee. Information responsibilities include preparation of manuscripts for ERDA patent clearance and publication release, maintenance of central files on all manuscripts and publications, preparation of the Annual Report, providing editorial and translation assistance, operation of a Technical Reading Room, operation of an ERDA Film Library, operation of a Reproduction Shop, providing copying services, and assisting visitors

  13. Physics as Information Processing

    International Nuclear Information System (INIS)

    D'Ariano, Giacomo Mauro

    2011-01-01

    I review some recent advances in foundational research at Pavia QUIT group. The general idea is that there is only Quantum Theory without quantization rules, and the whole Physics - including space-time and relativity - is emergent from the quantum-information processing. And since Quantum Theory itself is axiomatized solely on informational principles, the whole Physics must be reformulated in information-theoretical terms: this is the It from bit of J. A. Wheeler.The review is divided into four parts: a) the informational axiomatization of Quantum Theory; b) how space-time and relativistic covariance emerge from quantum computation; c) what is the information-theoretical meaning of inertial mass and of (ℎ/2π), and how the quantum field emerges; d) an observational consequence of the new quantum field theory: a mass-dependent refraction index of vacuum. I will conclude with the research lines that will follow in the immediate future.

  14. Defining Information Security.

    Science.gov (United States)

    Lundgren, Björn; Möller, Niklas

    2017-11-15

    This article proposes a new definition of information security, the 'Appropriate Access' definition. Apart from providing the basic criteria for a definition-correct demarcation and meaning concerning the state of security-it also aims at being a definition suitable for any information security perspective. As such, it bridges the conceptual divide between so-called 'soft issues' of information security (those including, e.g., humans, organizations, culture, ethics, policies, and law) and more technical issues. Because of this it is also suitable for various analytical purposes, such as analysing possible security breaches, or for studying conflicting attitudes on security in an organization. The need for a new definition is demonstrated by pointing to a number of problems for the standard definition type of information security-the so-called CIA definition. Besides being too broad as well as too narrow, it cannot properly handle the soft issues of information security, nor recognize the contextual and normative nature of security.

  15. Interactive Information Retrieval:

    DEFF Research Database (Denmark)

    Borlund, Pia

    IIR from the perspective of search dedication and task load in order to also include everyday life information seeking? With this presentation, the IIR community is invited to an exchange of ideas and is encouraged to engage in collaborations with the solving of these (and other) issues to our joint......This presentation addresses methodological issues of interactive information retrieval (IIR) evaluation in terms of what it entails to study users' use and interaction with IR systems, as well as their satisfaction with retrieved information. In particular, the presentation focuses on test design...... of the users to ensure a complete and realistic picture to enhance our understanding of IIR. The presentation also reflects on whether a re-thinking of the concept on an information need is necessary. One may ask whether it still makes sense to talk about types of information needs. Or should we rather study...

  16. Information Technology Resources Assessment

    Energy Technology Data Exchange (ETDEWEB)

    1993-04-01

    The Information Technology Resources Assessment (ITRA) is being published as a companion document to the Department of Energy (DOE) FY 1994--FY 1998 Information Resources Management Long-Range Plan. This document represents a collaborative effort between the Office of Information Resources Management and the Office of Energy Research that was undertaken to achieve, in part, the Technology Strategic Objective of IRM Vision 21. An integral part of this objective, technology forecasting provides an understanding of the information technology horizon and presents a perspective and focus on technologies of particular interest to DOE program activities. Specifically, this document provides site planners with an overview of the status and use of new information technology for their planning consideration.

  17. Quality of Information

    DEFF Research Database (Denmark)

    Christensen, Leif

    2016-01-01

    Accounting and auditing is closely related to the quality of data. Two important elements supporting the quality of information are internal controls and materiality. Inspired by Simons (1994), these elements can be considered “basic building blocks”. Internal controls are perhaps the most...... important element, as they ensure that information used for management purposes has the required quality (Kinney, 2000). This information can be used as a basis for preparing the external financial reporting (COSO, 2013) and as a prerequisite for establishing information-based management control systems...... (MCS) (Simons, 1994). When regarding management controls as a package, internal controls are part of the administrative controls and often formalised in policies and procedures (Malmi and Brown, 2008). The level of controls should be guided by the need for reliable information. These considerations...

  18. Information and Heterogeneous Beliefs

    DEFF Research Database (Denmark)

    Christensen, Peter Ove; Qin, Zhenjiang

    2014-01-01

    In an incomplete market with heterogeneous prior beliefs, we show public information can have a substantial impact on the ex ante cost of capital, trading volume, and investor welfare. The Pareto effcient public information system is the system enjoying the maximum ex ante cost of capital...... and the maximum expected abnormal trading volume. Imperfect public information increases the gains-to-trade based on heterogeneously updated posterior beliefs. In an exchange economy, this leads to higher growth in the investors' certainty equivalents and, thus, a higher equilibrium interest rate, whereas the ex...... ante risk premium is unaffected by the informativeness of the public information system. Similar results are obtained in a production economy, but the impact on the ex ante cost of capital is dampened compared to the exchange economy due to welfare improving reductions in real investments to smooth...

  19. Energy information directory 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-03-28

    The National Energy Information Center (NEIC), as part of its mission, provides energy information and referral assistance to Federal, State, and local governments, the academic community, business and industrial organizations, and the general public. The two principal functions related to this task are (1) operating a general access telephone line, and (2) responding to energy-related correspondence addressed to the Energy Information Administration (EIA). The Energy Information Directory was developed to assist the NEIC staff, as well as other Department of Energy (DOE) staff, in directing inquiries to the proper offices within DOE, other Federal agencies, or energy-related trade associations. The Directory is a list of most Government offices and trade associations that are involved in energy matters. It does not include those DOE offices which do not deal with the public or public information.

  20. Next generation information systems

    Energy Technology Data Exchange (ETDEWEB)

    Limback, Nathan P [Los Alamos National Laboratory; Medina, Melanie A [Los Alamos National Laboratory; Silva, Michelle E [Los Alamos National Laboratory

    2010-01-01

    The Information Systems Analysis and Development (ISAD) Team of the Safeguards Systems Group at Los Alamos National Laboratory (LANL) has been developing web based information and knowledge management systems for sixteen years. Our vision is to rapidly and cost effectively provide knowledge management solutions in the form of interactive information systems that help customers organize, archive, post and retrieve nonproliferation and safeguards knowledge and information vital to their success. The team has developed several comprehensive information systems that assist users in the betterment and growth of their organizations and programs. Through our information systems, users are able to streamline operations, increase productivity, and share and access information from diverse geographic locations. The ISAD team is also producing interactive visual models. Interactive visual models provide many benefits to customers beyond the scope of traditional full-scale modeling. We have the ability to simulate a vision that a customer may propose, without the time constraints of traditional engineering modeling tools. Our interactive visual models can be used to access specialized training areas, controlled areas, and highly radioactive areas, as well as review site-specific training for complex facilities, and asset management. Like the information systems that the ISAD team develops, these models can be shared and accessed from any location with access to the internet. The purpose of this paper is to elaborate on the capabilities of information systems and interactive visual models as well as consider the possibility of combining the two capabilities to provide the next generation of infonnation systems. The collection, processing, and integration of data in new ways can contribute to the security of the nation by providing indicators and information for timely action to decrease the traditional and new nuclear threats. Modeling and simulation tied to comprehensive

  1. Information als Prozess

    Directory of Open Access Journals (Sweden)

    Diether Elstner

    2010-10-01

    Full Text Available A unified definition of the phenomenon information is not possible at present, because of the enormous number of different views. The situation is increased by the 'Capurro‘s trilemma' which postulates the logical impossibility of a unified concept of information. There are two approaches in the literature, which aim to solve the trilemma. The first approach avoids collision with the trilemma through the introduction of a generalized parameter to form rules of language for information systems. The second approach is understood as a draft of a generalized understanding of information within a yet to be developed unified information science. This article presents the approach of understanding information as an instantaneous process, which effects changes in systems. These changes must be captured and reproduced by the organization of the system, otherwise they get lost by fluctuations. Information in this reductionist conception is possible in each system, under the assumption, that it has several stable states, which alternatively may be assumed by the system . The 'Capurro‘s trilemma' is negated.

  2. Acting to gain information

    Science.gov (United States)

    Rosenchein, Stanley J.; Burns, J. Brian; Chapman, David; Kaelbling, Leslie P.; Kahn, Philip; Nishihara, H. Keith; Turk, Matthew

    1993-01-01

    This report is concerned with agents that act to gain information. In previous work, we developed agent models combining qualitative modeling with real-time control. That work, however, focused primarily on actions that affect physical states of the environment. The current study extends that work by explicitly considering problems of active information-gathering and by exploring specialized aspects of information-gathering in computational perception, learning, and language. In our theoretical investigations, we analyzed agents into their perceptual and action components and identified these with elements of a state-machine model of control. The mathematical properties of each was developed in isolation and interactions were then studied. We considered the complexity dimension and the uncertainty dimension and related these to intelligent-agent design issues. We also explored active information gathering in visual processing. Working within the active vision paradigm, we developed a concept of 'minimal meaningful measurements' suitable for demand-driven vision. We then developed and tested an architecture for ongoing recognition and interpretation of visual information. In the area of information gathering through learning, we explored techniques for coping with combinatorial complexity. We also explored information gathering through explicit linguistic action by considering the nature of conversational rules, coordination, and situated communication behavior.

  3. Ignorance, information and autonomy.

    Science.gov (United States)

    Harris, J; Keywood, K

    2001-09-01

    People have a powerful interest in genetic privacy and its associated claim to ignorance, and some equally powerful desires to be shielded from disturbing information are often voiced. We argue, however, that there is no such thing as a right to remain in ignorance, where a fight is understood as an entitlement that trumps competing claims. This does not of course mean that information must always be forced upon unwilling recipients, only that there is no prima facie entitlement to be protected from true or honest information about oneself. Any claims to be shielded from information about the self must compete on equal terms with claims based in the rights and interests of others. In balancing the weight and importance of rival considerations about giving or withholding information, if rights claims have any place, rights are more likely to be defensible on the side of honest communication of information rather than in defence of ignorance. The right to free speech and the right to decline to accept responsibility to take decisions for others imposed by those others seem to us more plausible candidates for fully fledged rights in this field than any purported right to ignorance. Finally, and most importantly, if the right to autonomy is invoked, a proper understanding of the distinction between claims to liberty and claims to autonomy show that the principle of autonomy, as it is understood in contemporary social ethics and English law, supports the giving rather than the withholding of information in most circumstances.

  4. Accessibility and inclusion informational

    Directory of Open Access Journals (Sweden)

    Mônica Sena de Souza

    2013-06-01

    Full Text Available Introduction: Discusses the role of information professionals in meeting the informational demands of people with disabilities in the information society. The librarian is crucial for the effectiveness and success in the informational inclusion of people with disabilities, considering also continuing education for their professional qualification.Objective: To provide reflections on the role of the librarian in serving users with disabilities, highlighting the need for improvement in information units, identified in the scientific literature with regard to accessibility.Methodology: Literature search, based on a review of literature in books and scientific papers, highlighting the main authors: Adams (2000, Mazzoni (2001 and Sassaki (1997, 2002, 2005.Results: The lack of informational access for people with disabilities hampers their social and political participation, hence, reduces its condition of citizenship.Conclusion: The librarian responsible for seeking continuing education, greater involvement in the events of the area and the constant search for job training, which will reflect on the best service the information needs of users with disabilities.

  5. Information disclosure on transport

    International Nuclear Information System (INIS)

    Kubo, M.

    1998-01-01

    In Japan, the transport of nuclear fuel materials strictly meets the above international convention and domestic regulations as well. Information on the transport of nuclear fuel materials within the country and between the country and foreign countries is treated carefully. Nuclear fuel materials are categorized for transport and are physically protected accordingly. Certain transportation information is treated with special precautions, including prior arrangements among sender, recipient and carrier, and prior agreement between entities subject to the jurisdiction and regulation of supplier and recipient countries. In the case of international transport, this information includes specifying time, place and procedures for transferring transport and responsibility. (O.M.)

  6. Reframing information architecture

    CERN Document Server

    Resmini, Andrea

    2014-01-01

    Information architecture has changed dramatically since the mid-1990s and earlier conceptions of the world and the internet being different and separate have given way to a much more complex scenario in the present day. In the post-digital world that we now inhabit the digital and the physical blend easily and our activities and usage of information takes place through multiple contexts and via multiple devices and unstable, emergent choreographies. Information architecture now is steadily growing into a channel- or medium-specific multi-disciplinary framework, with contributions coming from a

  7. Future Information Technology

    CERN Document Server

    Stojmenovic, Ivan; Choi, Min; Xhafa, Fatos; FutureTech 2013

    2014-01-01

    Future technology information technology stands for all of continuously evolving and converging information technologies, including digital convergence, multimedia convergence, intelligent applications, embedded systems, mobile and wireless communications, bio-inspired computing, grid and cloud computing, semantic web, user experience and HCI, security and trust computing and so on, for satisfying our ever-changing needs. In past twenty five years or so, Information Technology (IT) influenced and changed every aspect of our lives and our cultures. These proceedings foster the dissemination of state-of-the-art research in all future IT areas, including their models, services, and novel applications associated with their utilization.

  8. Interviews with information receivers

    International Nuclear Information System (INIS)

    1997-11-01

    The Waste Policy Institute (WPI), through a cooperative agreement with the U.S. Department of Energy's (DOE) Office of Science and Technology (OST), conducted telephone interviews with people who requested OST publications to better understand why they wanted information from OST, how they used the information, and whether the information met their needs. Researchers selected 160 people who requested one of the two OST publications-either the Technology Summary Series (Rainbow Books) or the Initiatives newsletter. Of the 160 selected, interviewers spoke with 79 people nationwide representing six stakeholder audience categories

  9. Relying on the Information

    Directory of Open Access Journals (Sweden)

    TK YAYIN KURULU

    2013-11-01

    Full Text Available The editorial discusses internet filtering in the light of the optional internet packages for users, namely Family, Standard, Kids and Domestic, to be offered by the Information Technologies Board with the "Secure Internet Law" to take effect on August 22, 2011. Also sharing the hesitations about the objectivity of the application with the reader, editorial emphasizes an education system focused on breeding citizens who are not scared of relying on the information and who can, by themselves, decide whether information is harmful or not. References are made to the results of similar applications abroad while the press statement made by Turkish NGOs on the issue are included.

  10. PROLOGUE : Health Information System

    OpenAIRE

    Tomar, Shivanjali

    2013-01-01

    Prologue is a health information system developed for underserved communities in Bihar, India. It is aimed at helping people living in poverty and with low literacy to take the right steps to manage their and their family’s health. Bihar suffers from one of the worst healthcare records in the country. This is as much due to the lack of access to the right information as it is due to the economic condition of the region. The inaccessibility of information is aggravated by the complex social se...

  11. Information security management handbook

    CERN Document Server

    2002-01-01

    The Information Security Management Handbook continues its tradition of consistently communicating the fundamental concepts of security needed to be a true CISSP. In response to new developments, Volume 4 supplements the previous volumes with new information covering topics such as wireless, HIPAA, the latest hacker attacks and defenses, intrusion detection, and provides expanded coverage on security management issues and applications security. Even those that don't plan on sitting for the CISSP exam will find that this handbook is a great information security reference.The changes in the tech

  12. Advanced information society (11)

    Science.gov (United States)

    Nawa, Kotaro

    Late in the 1980's the information system of Japanese corporation has been operated strategically to strengthen its competitive position in markets rather than to make corporate management efficient. Therefore, information-oriented policy in the corporation is making remarkable progress. This policy expands the intelligence activity in the corporation and also leads to the extension of the market in an information industry. In this environment closed corporate system is transformed into open one. For this system network and database are important managerial resources.

  13. Quantum Information Processing

    CERN Document Server

    Leuchs, Gerd

    2005-01-01

    Quantum processing and communication is emerging as a challenging technique at the beginning of the new millennium. This is an up-to-date insight into the current research of quantum superposition, entanglement, and the quantum measurement process - the key ingredients of quantum information processing. The authors further address quantum protocols and algorithms. Complementary to similar programmes in other countries and at the European level, the German Research Foundation (DFG) started a focused research program on quantum information in 1999. The contributions - written by leading experts - bring together the latest results in quantum information as well as addressing all the relevant questions

  14. Accident information needs

    International Nuclear Information System (INIS)

    Hanson, D.J.; Arcieri, W.C.; Ward, L.W.

    1992-01-01

    A Five-step methodology has been developed to evaluate information needs for nuclear power plants under accident conditions and the availability of plant instrumentation during severe accidents. Step 1 examines the credible accidents and their relationships to plant safety functions. Step 2 determines the information personnel involved in accident management will need to understand plant behavior. Step 3 determines the capability of the instrumentation to function properly under severe accident conditions. Step 4 determines the conditions expected during the identified severe accidents. Step 5 compares the instrument capabilities and the severe accident conditions to evaluate the availability of the instrumentation to supply needed plant information

  15. Oxyfuels information needs

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-05-01

    Questions have been raised about the benefits and risks of oxygenated gasoline and reformulatd gasoline (`oxyfuels`). This document highlights areas of information that would improve scientific understanding of the impacts of these fuels on the environment and public health. It emphasizes the importance of obtaining data to support quantitative assessments of oxyfuels in comparison to conventional fuels. In addition to providing some background information and outlining a general framework for comparative risk assessments of fuels, the document briefly summarizes currently available information and then focuses on work that is now underway or planned and on data needs that remain to be filled.

  16. Accident information needs

    Energy Technology Data Exchange (ETDEWEB)

    Hanson, D.J.; Arcieri, W.C.; Ward, L.W.

    1992-12-31

    A Five-step methodology has been developed to evaluate information needs for nuclear power plants under accident conditions and the availability of plant instrumentation during severe accidents. Step 1 examines the credible accidents and their relationships to plant safety functions. Step 2 determines the information personnel involved in accident management will need to understand plant behavior. Step 3 determines the capability of the instrumentation to function properly under severe accident conditions. Step 4 determines the conditions expected during the identified severe accidents. Step 5 compares the instrument capabilities and the severe accident conditions to evaluate the availability of the instrumentation to supply needed plant information.

  17. Accident information needs

    Energy Technology Data Exchange (ETDEWEB)

    Hanson, D.J.; Arcieri, W.C.; Ward, L.W.

    1992-01-01

    A Five-step methodology has been developed to evaluate information needs for nuclear power plants under accident conditions and the availability of plant instrumentation during severe accidents. Step 1 examines the credible accidents and their relationships to plant safety functions. Step 2 determines the information personnel involved in accident management will need to understand plant behavior. Step 3 determines the capability of the instrumentation to function properly under severe accident conditions. Step 4 determines the conditions expected during the identified severe accidents. Step 5 compares the instrument capabilities and the severe accident conditions to evaluate the availability of the instrumentation to supply needed plant information.

  18. Information Technology Service

    International Nuclear Information System (INIS)

    Ageron, M.; Boninchi, V.; Chartoire, M.; Combroux, A.; Giraud, N.; Jacquet, G.; Lagrange, B.; Malleret, S.; Martin, C.; Mas, J.; Morgue, M.; Ollivier, T.

    1998-01-01

    The information technology service works out the choices concerning the information technology systems of general use in the laboratory: computers, network, peripherals, workstations, software. It intervenes at the same time in the definition of the procedures and equipment specific to the research groups. The entire data acquisition is centralized by the service. The personnel is sharing the following two large directions of activities: - management of information technology park (setup, configuration and maintenance of the materials and soft ensemble, training and assistance afforded to users); - participation in software projects either in elaboration of applications or in realization and maintenance of specific tools

  19. National Network for Immunization Information

    Science.gov (United States)

    ... American College of Obstetricians and Gynecologists . © Copyright National Network for Immunization Information. The information contained in the National Network for Immunization Information Web site should not be ...

  20. From Information Management to Information Visualization

    Science.gov (United States)

    Karami, Mahtab

    2016-01-01

    Summary Objective The development and implementation of a dashboard of medical imaging department (MID) performance indicators. Method Several articles discussing performance measures of imaging departments were searched for this study. All the related measures were extracted. Then, a panel of imaging experts were asked to rate these measures with an open ended question to seek further potential indicators. A second round was performed to confirm the performance rating. The indicators and their ratings were then reviewed by an executive panel. Based on the final panel’s rating, a list of indicators to be used was developed. A team of information technology consultants were asked to determine a set of user interface requirements for the building of the dashboard. In the first round, based on the panel’s rating, a list of main features or requirements to be used was determined. Next, Qlikview was utilized to implement the dashboard to visualize a set of selected KPI metrics. Finally, an evaluation of the dashboard was performed. Results 92 MID indicators were identified. On top of this, 53 main user interface requirements to build of the prototype of dashboard were determined. Then, the project team successfully implemented a prototype of radiology management dashboards into study site. The visual display that was designed was rated highly by users. Conclusion To develop a dashboard, management of information is essential. It is recommended that a quality map be designed for the MID. It can be used to specify the sequence of activities, their related indicators and required data for calculating these indicators. To achieve both an effective dashboard and a comprehensive view of operations, it is necessary to design a data warehouse for gathering data from a variety of systems. Utilizing interoperability standards for exchanging data among different systems can be also effective in this regard. PMID:27437043

  1. Flu Vaccine Safety Information

    Science.gov (United States)

    ... Influenza Types Seasonal Avian Swine Variant Pandemic Other Flu Vaccine Safety Information Questions & Answers Language: English (US) ... safety of flu vaccines monitored? Egg Allergy Are flu vaccines safe? Flu vaccines have good safety record. ...

  2. Rural Health Information Hub

    Science.gov (United States)

    ... U.S. (2011-2015): Individual-level & Placed-based Disparities Source: Southwest Rural Health Research Center Online Library » Resource and Referral Service Need help finding information? RHIhub can provide free assistance customized to your ...

  3. Coal information 1995

    International Nuclear Information System (INIS)

    1996-01-01

    This volume is a comprehensive reference book on current world coal market trends and long-term prospects to 2010. It contains an in-depth analysis of the 1995 international coal market covering prices, demand, trade, supply and production capacity as well as over 450 pages of country specific statistics on OECD and key non-OECD coal producing and consuming countries. The book also includes a summary of environmental policies on climate change and on coal-related air quality issues as well as essential facts on coal-fired power stations in coal-importing regions, on coal ports world-wide and on emission standards for coal-fired boilers in OECD countries. Coal Information is one of a series of annual IEA statistical publications on major energy sources; other reports are Oil and Gas Information and Electricity Information. Coal Information 1995 is published in July 1996. (author)

  4. Information Management in Communication

    OpenAIRE

    Alemany, Dolores

    2014-01-01

    The history of books, libraries, catalogues and the first archives. Typology of information resources and retrieval methods associated to them. A recollection of resources especially meant for students and professionals in the area of Advertising and Public Relations.

  5. INFORMATION TECHNOLOGIES IN TOURISM

    Directory of Open Access Journals (Sweden)

    Radka Tosheva

    2016-12-01

    Full Text Available In this article the focus is on the role of information technology in tourism, tourism business, electronic payments, software used by tourist companies, new technologies for online advertising and shopping, software for mobile devices.

  6. Wave theory of information

    CERN Document Server

    Franceschetti, Massimo

    2017-01-01

    Understand the relationship between information theory and the physics of wave propagation with this expert guide. Balancing fundamental theory with engineering applications, it describes the mechanism and limits for the representation and communication of information using electromagnetic waves. Information-theoretic laws relating functional approximation and quantum uncertainty principles to entropy, capacity, mutual information, rate distortion, and degrees of freedom of band-limited radiation are derived and explained. Both stochastic and deterministic approaches are explored, and applications for sensing and signal reconstruction, wireless communication, and networks of multiple transmitters and receivers are reviewed. With end-of-chapter exercises and suggestions for further reading enabling in-depth understanding of key concepts, it is the ideal resource for researchers and graduate students in electrical engineering, physics and applied mathematics looking for a fresh perspective on classical informat...

  7. Carbon Monoxide Information Center

    Medline Plus

    Full Text Available ... Us Sitemap RSS E-mail Inside CPSC Accessibility Privacy Policy Budget, Performances & Finance Open Government Freedom of Information (FOIA) Inspector General No Fear Act Data USA.gov Report an Unsafe Product Contact Us: ...

  8. Information and Announcements

    Indian Academy of Sciences (India)

    Information and Announcements. lfijRefresher Course in ... Classical encrypton techniques, block ciphers and DES, AES, confidentiality using symmetric encryption, message ... network security', W Stallings, PHI, III Ed. (2004). Recent trends in ...

  9. Informational system. Documents management

    Directory of Open Access Journals (Sweden)

    Vladut Iacob

    2009-12-01

    Full Text Available Productivity growing, as well as reducing of operational costs in a company can be achieved by adopting a document management solutions. Such application will allow management and structured and efficient transmission of information within the organization.

  10. Information retrieval system

    Science.gov (United States)

    Berg, R. F.; Holcomb, J. E.; Kelroy, E. A.; Levine, D. A.; Mee, C., III

    1970-01-01

    Generalized information storage and retrieval system capable of generating and maintaining a file, gathering statistics, sorting output, and generating final reports for output is reviewed. File generation and file maintenance programs written for the system are general purpose routines.

  11. Health Information Systems

    International Development Research Centre (IDRC) Digital Library (Canada)

    the technology and expertise to process and share ... services. GEHS supports efforts that reach beyond healthcare institutions to capture evidence ... Health information systems are a foundation for quality care, and can increase accountability ...

  12. Information Engineering and Applications

    CERN Document Server

    Ma, Yan; International Conference on Information Engineering and Applications (IEA) 2011

    2012-01-01

    The International Conference on Information Engineering and Applications (IEA) 2011 will be held on October 21-24, 2011, in Chongqing, China. It is organized by Chongqing Normal University, Chongqing University, Shanghai Jiao Tong University, Nanyang Technological University, the University of Michigan, Chongqing University of Arts and Sciences, and sponsored by the National Natural Science Foundation of China. The objective of IEA 2011 is to facilitate an exchange of information on best practices for the latest research advances in the area of information engineering and intelligence applications, which mainly includes computer science and engineering, informatics, communications and control, electrical engineering, information computing, business intelligence and management. IEA 2011 will provide a forum for engineers and scientists in academia, industry, and government to address the most innovative research and development including technical challenges, social and economic issues, and to present and disc...

  13. State Traffic Safety Information

    Data.gov (United States)

    Department of Transportation — The State Traffic Safety Information (STSI) portal is part of the larger Fatality Analysis Reporting System (FARS) Encyclopedia. STSI provides state-by-state traffic...

  14. National oceanographic information system

    Digital Repository Service at National Institute of Oceanography (India)

    Desai, B.N.; Kunte, P.D.; Bhargava, R.M.S.

    Ocean study is inherently interdisciplinary and therefore calls for a controlled and integrated approach for information generation, processing and decision making. In this context, Indian National Oceanographic Data Centre (INODC) of National...

  15. Integrated Reporting Information System -

    Data.gov (United States)

    Department of Transportation — The Integrated Reporting Information System (IRIS) is a flexible and scalable web-based system that supports post operational analysis and evaluation of the National...

  16. Afghanistan / Pakistan Information Database

    Data.gov (United States)

    US Agency for International Development — USAID Info is a dynamic, web-based information management application designed to organize, monitor, and store OAPA Missions? implementation- and performance-level...

  17. Gas information campaign

    Energy Technology Data Exchange (ETDEWEB)

    Berthold, D.

    The second Federal German experts' meeting on Gas Consulting from 2nd to 5th June 1981 in Saarbruecken documents the importance attached by the gas industry to a qualified energy consulting. The consumers are informed of natural gas by country-wide and regional PR- and marketing activities. This information is the basis for sales promotion measures in the regional and local sphere. All communicative measures end with the consulting. It is the most important sales-political instrument which helps the supply companies to win interested and informed customers. The action gas consulting shows possibilities of how to effect an advisory service in cooperation between Information on Natural Gas and local suppliers.

  18. Information Technology Industry 2004

    National Research Council Canada - National Science Library

    Altieri, Richard; Buccheit, Nathan; Burke, Kyle; Dillard, Norvel; Dolan, Patrick; Edwards, Gregory; Elins, Daniel; Gaines, Leonard; Goodwin, Steven; Lawrence, Michael

    2004-01-01

    Forging an unprecedented partnership between the public and private sectors is essential to protect the vital interests of the United States in the wake of the ongoing Information Technology Revolution...

  19. Quantum information theory

    CERN Document Server

    Wilde, Mark M

    2017-01-01

    Developing many of the major, exciting, pre- and post-millennium developments from the ground up, this book is an ideal entry point for graduate students into quantum information theory. Significant attention is given to quantum mechanics for quantum information theory, and careful studies of the important protocols of teleportation, superdense coding, and entanglement distribution are presented. In this new edition, readers can expect to find over 100 pages of new material, including detailed discussions of Bell's theorem, the CHSH game, Tsirelson's theorem, the axiomatic approach to quantum channels, the definition of the diamond norm and its interpretation, and a proof of the Choi–Kraus theorem. Discussion of the importance of the quantum dynamic capacity formula has been completely revised, and many new exercises and references have been added. This new edition will be welcomed by the upcoming generation of quantum information theorists and the already established community of classical information theo...

  20. Carbon Monoxide Information Center

    Medline Plus

    Full Text Available ... 150 people in the Unites States die every year from accidental non-fire related CO poisoning associated ... or the information it contains by CPSC or any of its employees. Click Ok if you wish ...

  1. Remote Sensing Information Gateway

    Science.gov (United States)

    Remote Sensing Information Gateway, a tool that allows scientists, researchers and decision makers to access a variety of multi-terabyte, environmental datasets and to subset the data and obtain only needed variables, greatly improving the download time.

  2. Brownfields Grants Information

    Data.gov (United States)

    U.S. Environmental Protection Agency — This asset includes all types of information regarding Brownfields grant programs that subsidize/support Brownfield cleanup. This includes EPA's Brownfields Program...

  3. Therapy Provider Phase Information

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Therapy Provider Phase Information dataset is a tool for providers to search by their National Provider Identifier (NPI) number to determine their phase for...

  4. Energy Information Systems

    Science.gov (United States)

    Home > Building Energy Information Systems and Performance Monitoring (EIS-PM) Building Energy evaluate and improve performance monitoring tools for energy savings in commercial buildings. Within the and visualization capabilities to energy and facility managers. As an increasing number of

  5. Carbon Monoxide Information Center

    Medline Plus

    Full Text Available ... International Newsroom About CPSC Contact Us Sitemap RSS E-mail Inside CPSC Accessibility Privacy Policy Budget, Performances & ... Subscribe to CPSC News and Information Sitemap RSS E-mail Accessibility Privacy Policy Budget & Performance Open Government ...

  6. Information Operations: Where Next?

    National Research Council Canada - National Science Library

    Buchholz, David R

    2005-01-01

    ... to standardized IO training and integration across the combatant commands. For this reason and others there is a compelling argument for the major responsibility for DoD information operations integration to fall under the control of U.S...

  7. Retirement Information Center Blog

    Data.gov (United States)

    Office of Personnel Management — A place for the U.S. Office of Personnel Management (OPM) to share information about retirement benefits for new, prospective, and current Federal employees, as well...

  8. Matter Tracking Information System -

    Data.gov (United States)

    Department of Transportation — The Matter Tracking Information System (MTIS) principle function is to streamline and integrate the workload and work activity generated or addressed by our 300 plus...

  9. Carbon Monoxide Information Center

    Medline Plus

    Full Text Available ... as CO, is called the "Invisible Killer" because it's a colorless, odorless, poisonous gas. More than 150 ... Working CO alarms matter. Install one and check its batteries regularly. View Information About CO Alarms Other ...

  10. Audit Information Management System

    Data.gov (United States)

    US Agency for International Development — USAID/OIG has initiated its new Audit Information Management System (AIMS) to track OIG's audit recommendations and USAID's management decisions. OIG's in-house...

  11. Chemical Speciation - General Information

    Science.gov (United States)

    This page includes general information about the Chemical Speciation Network that is not covered on the main page. Commonly visited documents, including calendars, site lists, and historical files for the program are listed here

  12. Carbon Monoxide Information Center

    Medline Plus

    Full Text Available ... OnSafety Blog Safety Education Centers Neighborhood Safety Network Community Outreach Resource Center Toy Recall Statistics CO Poster ... Sitemap RSS E-mail Inside CPSC Accessibility Privacy Policy Budget, Performances & Finance Open Government Freedom of Information ( ...

  13. Enforcement Information System

    Data.gov (United States)

    Department of Transportation — EIS is an automated management information system that tracks the FAA’s enforcement actions on a nationwide basis. EIS is the FAA’s primary database for tracking...

  14. Entropy and information

    CERN Document Server

    Volkenstein, Mikhail V

    2009-01-01

    The book "Entropy and Information" deals with the thermodynamical concept of entropy and its relationship to information theory. It is successful in explaining the universality of the term "Entropy" not only as a physical phenomenon, but reveals its existence also in other domains. E.g., Volkenstein discusses the "meaning" of entropy in a biological context and shows how entropy is related to artistic activities. Written by the renowned Russian bio-physicist Mikhail V. Volkenstein, this book on "Entropy and Information" surely serves as a timely introduction to understand entropy from a thermodynamic perspective and is definitely an inspiring and thought-provoking book that should be read by every physicist, information-theorist, biologist, and even artist.

  15. College Information Needs.

    Science.gov (United States)

    Cibik, Margaret A.

    1982-01-01

    A survey of a sampling of college-bound high school seniors in Arizona was undertaken to determine students' information needs for college choice. Items, including institutional, student, and program characteristics, are ranked in order of perceived importance. (MSE)

  16. OEM Emergency Response Information

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Office of Emergency Management retains records of all incident responses in which it participates. This data asset includes three major sources of information:...

  17. Labor Informality: General Causes

    Directory of Open Access Journals (Sweden)

    Gustavo Sandoval Betancour

    2016-04-01

    Full Text Available The article examines the main causes of labor informality in order to verify the validity of classical theories that explain unemployment in market economies and its relationship to informality. Methodologically, the project was based, in the empirical part, on international statistics, comparing the evolution of labor market structure in a combined sample of highly industrialized countries and other less industrialized ones. Empirical evidence supports the conclusion that the classical economic theory of Marxist origin is inefficient to explain the causes of unemployment in contemporary market economies, as well as it fails to satisfactorily explain informality. On the contrary, we conclude that the theory in question is more relevant to explain informality in centrally planned economies where this phenomenon has been present even more significantly than in free market economies.

  18. Management Information Systems

    Directory of Open Access Journals (Sweden)

    Furduescu Bogdan-Alexandru

    2017-12-01

    Full Text Available Technology is the science that studies processes, methods and operations run or applied onto raw materials, matters or data, in order to obtain a certain product. Information is the material signal able to launch a material reaction of a dynamic auto-tuning system for which the system is conditioned and finalized. Information Technology is the technology needed for handling (procuring, processing, storing converting and transmitting information, in particular, with the use of computers [Longley, D. & Shain, M. (1985, p. 164]. The importance of IT in the economic growth and development is widely known, taking into account the impact that technology can have on the success and survival, or the failure of the economic activity of enterprises/organizations, IT offering various management information systems (MIS, executive and feedback segments, which all have important and beneficial implications in management and control.

  19. Border information flow architecture

    Science.gov (United States)

    2006-04-01

    This brochure describes the Border Information Flow Architecture (BIFA). The Transportation Border Working Group, a bi-national group that works to enhance coordination and planning between the United States and Canada, identified collaboration on th...

  20. OEM Emergency Preparedness Information

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Office of Emergency Management compiles a wide variety of information in support of Emergency Preparedness, including certain elements of the System for Risk...