WorldWideScience

Sample records for profuse interregional connectivity

  1. Node Identification Using Inter-Regional Correlation Analysis for Mapping Detailed Connections in Resting State Networks

    Directory of Open Access Journals (Sweden)

    Yong Jeong

    2017-05-01

    Full Text Available Brain function is often characterized by the connections and interactions between highly interconnected brain regions. Pathological disruptions in these networks often result in brain dysfunction, which manifests as brain disease. Typical analysis investigates disruptions in network connectivity based correlations between large brain regions. To obtain a more detailed description of disruptions in network connectivity, we propose a new method where functional nodes are identified in each region based on their maximum connectivity to another brain region in a given network. Since this method provides a unique approach to identifying functionally relevant nodes in a given network, we can provide a more detailed map of brain connectivity and determine new measures of network connectivity. We applied this method to resting state fMRI of Alzheimer's disease patients to validate our method and found decreased connectivity within the default mode network. In addition, new measure of network connectivity revealed a more detailed description of how the network connections deteriorate with disease progression. This suggests that analysis using key relative network hub regions based on regional correlation can be used to detect detailed changes in resting state network connectivity.

  2. Differences in interregional brain connectivity in children with unilateral hearing loss.

    Science.gov (United States)

    Jung, Matthew E; Colletta, Miranda; Coalson, Rebecca; Schlaggar, Bradley L; Lieu, Judith E C

    2017-11-01

    To identify functional network architecture differences in the brains of children with unilateral hearing loss (UHL) using resting-state functional-connectivity magnetic resonance imaging (rs-fcMRI). Prospective observational study. Children (7 to 17 years of age) with severe to profound hearing loss in one ear, along with their normal hearing (NH) siblings, were recruited and imaged using rs-fcMRI. Eleven children had right UHL; nine had left UHL; and 13 had normal hearing. Forty-one brain regions of interest culled from established brain networks such as the default mode (DMN); cingulo-opercular (CON); and frontoparietal networks (FPN); as well as regions for language, phonological, and visual processing, were analyzed using regionwise correlations and conjunction analysis to determine differences in functional connectivity between the UHL and normal hearing children. When compared to the NH group, children with UHL showed increased connectivity patterns between multiple networks, such as between the CON and visual processing centers. However, there were decreased, as well as aberrant connectivity patterns with the coactivation of the DMN and FPN, a relationship that usually is negatively correlated. Children with UHL demonstrate multiple functional connectivity differences between brain networks involved with executive function, cognition, and language comprehension that may represent adaptive as well as maladaptive changes. These findings suggest that possible interventions or habilitation, beyond amplification, might be able to affect some children's requirement for additional help at school. 3b. Laryngoscope, 127:2636-2645, 2017. © 2017 The American Laryngological, Rhinological and Otological Society, Inc.

  3. Introduction to Interregional Place Branding

    DEFF Research Database (Denmark)

    Zenker, Sebastian; Jacobsen, Björn P.

    2015-01-01

    Place branding is an inherently difficult venture, since places are complex systems of geographical abstractions, each one understood in relation and contrast to other geographical entities. Even at the smallest size – a district, town, or city – a place is quite complex, but it becomes even more...... challenging when the entity exists on a higher level, like a region, two or more joined regions, or a country. When performing place branding, regions often not only differentiate themselves but also cooperate (within one country or between countries), thereby building so-called interregional brands...... with a high degree of complexity. In this chapter, we will define the place brand and examine different concepts to understand branding as they relate to places. In a next step, we will highlight the special character of interregional place branding. Finally, we will apply these concepts to a particular...

  4. Introduction: interregional relations in the world order

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    Jordi Bacaria

    2015-09-01

    Full Text Available This article will analyse factors which, since the end of last century, have made interregional relations very important to understand the world geopolitical and economic order. Interregional relations are defined as those which pertain to relations between regions or between a given state and a given region, or within a megaregion. This evolution results from: the growing demand in the emerging economies and the interaction among them, a new framework of interregional economic relations, and the development of new commercial channels. Finally, this paper will introduce the different articled included in this issue.

  5. Tentorial cavernous angioma with profuse bleeding. Case report.

    Science.gov (United States)

    Mori, Hiroshi; Koike, Toshiro; Endo, Shin; Takii, Yoshitaka; Uzuka, Takeo; Takahashi, Hitoshi; Ito, Jusuke; Tanaka, Ryuichi

    2009-01-01

    This 15-year-old boy with a tentorial cavernous angioma reported occasional headache and scintillation in his left visual field. Magnetic resonance imaging revealed a well-demarcated, homogeneously enhanced tumor originating from the right cerebellar tentorium and extending into both the supratentorial and infratentorial spaces. Although a meningioma was suspected, vertebral artery angiography revealed a thickened meningeal branch originating from the right posterior inferior cerebellar artery and flecked tumor stain with pooling of contrast medium until the late venous phase. A cavernous angioma of the tentorium was suspected based on this finding, and as expected from the radiological findings, profuse bleeding was encountered during tumor removal. The histological diagnosis was a cavernous angioma. A cavernous angioma of the tentorium is extremely rare but should be differentiated from a meningioma preoperatively given that a cavernous angioma of dural origin tends to bleed massively during removal.

  6. Interregional migration in socialist countries: the case of China.

    Science.gov (United States)

    Wei, Y

    1997-03-01

    "This paper analyzes changing interregional migration in China and reveals that the recent eastward migration reverses patterns of migration under Mao. It finds that investment variables are more important than the conventional variables of income and job opportunities in determining China's recent interregional migration. It suggests that both state policy and the global force influence interregional migration, challenging the popular view that the socialist state is the only critical determinant. This paper also criticizes Mao's approach to interregional migration and discusses the impact of migration on development." excerpt

  7. The Optimization Model for Interregional Power System Planning considering Carbon Emissions Trading and Renewable Energy Quota Mechanism

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    Liwei Ju

    2016-01-01

    Full Text Available In China, the rapid construction of ultra-high-voltage (UHV transmission lines promotes interregional resource optimizing configuration and interregional power system planning. This paper analyzes external environment of interregional power system planning from geographical, technical, and policy environments. Then, the paper takes the minimum system investment cost as the optimization objective and constructs the optimization model of interregional power system planning considering carbon emissions trading (CET and renewable energy quota mechanism (REQ. Finally, this paper sets base scenario, carbon emissions trading scenario, renewable energy quota mechanism scenario, and comprehensive scenario for case simulation. The results show that interregional power system planning could connect power grids in different regions, enlarge wind power consumption space, and relieve the inconformity problem between power resource and load demand. CET and REQ can increase the installed proportion of clean energy and reduce carbon dioxide emissions, but the cost of transmission lines construction and system reserve will increase correspondingly. The optimization effect of REQ on power system planning is better than CET. When they are both introduced, the power structure will reach the best, carbon dioxide emissions will achieve the minimum, and comprehensive benefits will become more balanced.

  8. Social networks and trade of services: modelling interregional flows with spatial and network autocorrelation effects

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    de la Mata, Tamara; Llano, Carlos

    2013-07-01

    Recent literature on border effect has fostered research on informal barriers to trade and the role played by network dependencies. In relation to social networks, it has been shown that intensity of trade in goods is positively correlated with migration flows between pairs of countries/regions. In this article, we investigate whether such a relation also holds for interregional trade of services. We also consider whether interregional trade flows in services linked with tourism exhibit spatial and/or social network dependence. Conventional empirical gravity models assume the magnitude of bilateral flows between regions is independent of flows to/from regions located nearby in space, or flows to/from regions related through social/cultural/ethic network connections. With this aim, we provide estimates from a set of gravity models showing evidence of statistically significant spatial and network (demographic) dependence in the bilateral flows of the trade of services considered. The analysis has been applied to the Spanish intra- and interregional monetary flows of services from the accommodation, restaurants and travel agencies for the period 2000-2009, using alternative datasets for the migration stocks and definitions of network effects.

  9. Federal transfers, interregional inequality and redistribution in Latin America

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    Lucas GONZÁLEZ

    2014-08-01

    Full Text Available This work analyzes the impact of federal transfers and subnational expenditure in human development and interregional equity. Data on federal transfers and subnational spending in Argentina, Brazil, Mexico, Chile, and Colombia, between 1983 and 2011, indicate that the redistributive power of the central government is statistically associated with improvements in interregional equity but not with better values in the human development index. Exactly the opposite results are found for subnational social spending.

  10. Genetic mapping of Sbbmc, a major locus controlling the profuse wax trait of sorghum

    Science.gov (United States)

    Sorghum bicolor is one of the most valuable “fail safe” cereal crop species and is a rich repository of genes for abiotic stress tolerance that await discovery. As an example, Sorghum exhibits cuticle which produces profuse amount of epicuticular wax (bloom) on sheaths and leaves that serves as one...

  11. Interregional flows of ecosystem services: Concepts, typology and four cases

    Science.gov (United States)

    Schröter, Matthias; Koellner, Thomas; Alkemade, Rob; Arnhold, Sebastian; Bagstad, Kenneth J.; Frank, Karin; Erb, Karl-Heinz; Kastner, Thomas; Kissinger, Meidad; Liu, Jianguo; López-Hoffman, Laura; Maes, Joachim; Marques, Alexandra; Martín-López, Berta; Meyer, Carsten; Schulp, Catharina J. E.; Thober, Jule; Wolff, Sarah; Bonn, Aletta

    2018-01-01

    Conserving and managing global natural capital requires an understanding of the complexity of flows of ecosystem services across geographic boundaries. Failing to understand and to incorporate these flows into national and international ecosystem assessments leads to incomplete and potentially skewed conclusions, impairing society’s ability to identify sustainable management and policy choices. In this paper, we synthesise existing knowledge and develop a conceptual framework for analysing interregional ecosystem service flows. We synthesise the types of such flows, the characteristics of sending and receiving socio-ecological systems, and the impacts of ecosystem service flows on interregional sustainability. Using four cases (trade of certified coffee, migration of northern pintails, flood protection in the Danube watershed, and information on giant pandas), we test the conceptual framework and show how an enhanced understanding of interregional telecouplings in socio-ecological systems can inform ecosystem service-based decision making and governance with respect to sustainability goals.

  12. The politics of inter-regionalism: Relations between international regional organizations

    NARCIS (Netherlands)

    Vleuten, J.M. van der; Ribeiro Hoffman, A.

    2013-01-01

    As the development of relations between international regional organizations, inter-regionalism denotes a relatively recent phenomenon. Largely due to systemic bipolarity, inter-regional relations remained limited to 'dialogue partnerships' between the European Community (EC) and other regional

  13. Interregional migration pattern in Slovakia: efficiency analysis and demographic consequences.

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    Podolak, P

    1995-01-01

    The patterns of interregional migration within Slovakia from 1970 to 1990 and their consequences for the Slovakian population are analyzed. The author calculates the migration efficiency, or net movement of population relative to total migration, for each administrative district. He concludes that interregional migration has declined both absolutely and as a percentage of total migration, and that a trend toward short-distance migration has become evident. As migration between the north-western and south-eastern part of the country has declined, intraregional rural-urban migration has increased.

  14. Decentralisation and Interregional Redistribution in the Italian Education System

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    Ferrari, Irene; Zanardi, Alberto

    2014-01-01

    The aim of this paper is to evaluate the potential impact of the reform designed to decentralise public education in Italy, currently under discussion, on interregional redistribution. The central government has always played a prominent financial and administrative role in the provision of compulsory education in Italy. This has had a strong…

  15. Acute Local Spontaneous and Profuse Gingival Hemorrhage during Neoadjuvant Treatment with Paclitaxel and Trastuzumab

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    Nima D. Sarmast

    2016-06-01

    Full Text Available This case report describes a 33-year-old female currently undergoing breast cancer treatment following the AC-T-T (doxorubicin hydrochloride (Adriamycin and cyclophosphamide followed by paclitaxel (Taxol and trastuzumab (Herceptin treatment regimen. Her chief complaint at the time of the emergency visit at the dental office was that she had an episode of profuse spontaneous bleeding located at the palatal gingiva in the maxilla between the left central and lateral incisor. To our knowledge, this is a novel finding related to the medications she is utilizing and should be further investigated.

  16. Local pottery production and Interregional exchange in Middle Helladic Boeotia

    DEFF Research Database (Denmark)

    Sarri, Kalliopi; Tartaron, Thomas; Boileau, Marie-Claude

    2007-01-01

    In an effort to investigate local pottery production in Boeotia and interregional exchange during the Middle Helladic period (ca. 2000-1675 BCE) this paper examines the integration of petrographic data to fine-grained stylistic classification of monochrome burnished grey, yellow, brown and red...... lithologies with ophiolite outcrops. Furthermore, ‘local’ coarse petrofabrics, manufactured with calcareous-poor clays, show a great degree of compositional heterogeneity which does not parallel the stylistic classification scheme. It appears that more than one workshop was involved in the production...

  17. Interregional structure of the U. S. coal economy

    Energy Technology Data Exchange (ETDEWEB)

    Libbin, J.D.; Boehlje, M.D.

    1977-08-01

    A multiperiod spatial equilibrium model of the national coal economy is developed to evaluate future interregional shifts in coal production and the investment requirements and sequencing for exploitation of a nonrenewable, variable quality resource. The effects of alternative sulfur dioxide emission standards and demand growth projections on the location and type of coal production, the transportation industry, and capital markets are examined. The study concludes that the coal industry can expand through 1990, especially in Appalachia and the West, to meet both greatly increased demand and restrictive air quality standards at moderately increased cost.

  18. Interregional migration in Indonesia. Macro, micro, and agent-based modelling approaches

    NARCIS (Netherlands)

    Wajdi, N.

    2017-01-01

    This thesis aims to explain the dynamics of interregional migration in Indonesia in the 2000-2010 period and to project migration dynamics up to 2035. Four empirical studies presented in this thesis are interregional migration flows in Indonesia, migration and its relation to macro factors,

  19. Inter-regional output distribution: a comparison of Russian and Chinese experience

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    Herzfeld, T.

    2008-01-01

    Several studies report increasing inter-regional inequality in transition countries over the course of economic reforms, but most of them fail to look at the underlying dynamics. Using the cases of Russia and China, this article analyses the evolution of inter-regional output distribution during

  20. THE COMPILATION OF CHINA’S INTERREGIONAL INPUT–OUTPUT MODEL 2002

    NARCIS (Netherlands)

    Zhang, Zhuoying; Shi, Minjun; Zhao, Zhao

    2015-01-01

    The increasing economic interaction among various regions in China makes the construction of an interregional input–output table relevant for economic studies. This paper elaborates the model compilation procedure of the China Interregional Input–output model 2002. The key features of the model

  1. Interregional Cooperation in the Emerging Eurasian Economic Space

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    Konstantin Anatol’evich Gulin

    2015-11-01

    Full Text Available In 2015 the Treaty on the Eurasian Economic Union entered into force and presented a new stage of reintegration of the countries on the territory of the former USSR. The success of this project will depend not only on collaboration at the national level, but also on the degree of the EEU countries’ involvement in the integration process. The academic debate on this issue is a relevant and practically important task. The article highlights the results of the international online-conference “Interregional cooperation in the emerging Eurasian Economic Space”, conducted by the Institute of Socio-Economic Development of Territories of RAS June, 16–20 2015. It considers the issues associated with interregional trade and economic cooperation, interaction in the sphere of science and innovation and various aspects of humanitarian cooperation. It raises important problems of cross-border cooperation of the EEU states. The article makes a conclusion about the need to develop the integration process both in scope (through expanded directions of cooperation, which should not be limited only to contacts at the highest political level or trade partnership and depth (through involvement of regions, enterprises, different social groups, individual citizens

  2. Managing Water Scarcity : An Evaluation of Interregional Transfers

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    Vaux, H. J., Jr.; Howitt, Richard E.

    1984-07-01

    An interregional trade model is developed for assessing the potential of limited market institutions to alleviate water scarcity. The model differs from those of Takayama and Judge, since curvilinear demand functions are employed and an unequal number of supply and demand regions are specified. The model is applied to California using regional supply and demand functions estimated for 1980, 1995, and 2020. The results show that water transfers can be substituted for new supplies to the extent that less than 100,000 ac ft (123 × 106 m3) of new capacity could be justified by 2020. The net benefits to buyers and sellers total 66 million for 1980 and rise to 219 million by 2020. The work also demonstrates that trade would lead to premature drawdown of groundwater resources in the absence of management and might create excess supply capacity for urban regions.

  3. Low-frequency connectivity is associated with mild traumatic brain injury

    National Research Council Canada - National Science Library

    Dunkley, B.T; Da Costa, L; Bethune, A; Jetly, R; Pang, E.W; Taylor, M.J; Doesburg, S.M

    2015-01-01

    .... Changes in local spectral power, particularly low-frequency amplitude increases and/or peak alpha slowing have been reported in mTBI, but large-scale connectivity metrics based on inter-regional...

  4. A balanced way for China's inter-regional cross-border insolvency cooperation

    NARCIS (Netherlands)

    Gong, X.

    2016-01-01

    In pursuit of solutions to China’s inter-regional cross-border insolvency cooperation, the doctoral dissertation provides 10 original recommendations accompanied with comments, which are entitled “CICIA”.

  5. Typological and qualitative characteristics of Greek-interregional rivers

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    N.TH. SKOULIKIDIS

    2002-06-01

    Full Text Available The catchments of the interregional rivers (I.R. entering Greece cover an area of approximately 98000 km2, of which only 14% belongs to Greece, while their contribution to the country’s freshwater runoff reach 40% (18 km3/a. Geologically, the I.R. catchments are marked by their high percentage of acid silicates. I.R. show hydrochemical similarities, except for Evros, which is highly polluted. Compared to the other major Greek rivers, I.R. are the most polluted, with the Evros at the top, followed by the Axios. The main factors controlling their composition are climate, pollution and catchment geology. Inter-annual qualitative variations are controlled by seasonal climatic variations, which govern evaporation, groundwater contribution to river flow, dilution and flushing. A long-term salinisation of river water is attributed to climatic and anthropogenic impact. The I.R. transfer approx. 6,63 Μ t dissolved solids to the sea annually. Regarding the inputs of pollutants into the sea, they transfer over 70 % of the potassium, nitrate and dissolved organic carbon of the total load carried by major Greek rivers (78% of total Greek surface runoff, whereas for phosphate and sulphate the percentages reach 89 and 78.

  6. Cloud Service for Interactive Simulation of Interregional Trade

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    A. S. Velichko

    2016-01-01

    Full Text Available The paper describes a mathematical model of trade flows between the territories of a region or a country in a transport network having one or more different types of marine or ground transportation. We use the approach of modeling complex communication systems to determine the most probable values of flows in case of incomplete information about the system. Transport costs between the territories are modeled within the framework of the gravity model. The payment for transportation depends on the distance between regions, the distance is estimated as the shortest way length in a given transport network or geographical distance. The mathematical formulation of the problem belongs to the class of convex mathematical programming problems and assumes the numerical solution of nonlinear optimization problem with linear constraints. Based on the model, the software is implemented as a cloud service on heterogeneous computing architectures: the simulation module is made on a highperformance server platform, management and visualization modules are produced with IACPaaS cloud platform. Communication between the platforms is established via asynchronous http-queries. For information exchange between the modules the declarative model with JSON format is developed and implemented for the objects considered in the mathematical model which are products, areas and communications. Visualization module allows to present graphically the original and the resulting matrix data and to modify the input parameters of the model interactively. The paper demonstrates the use of software for the simulation of inter-regional freight traffic of the Russian Far East region based on input data provided by open statistics sources.

  7. Cerebral interregional correlations of associative language processing: a positron emission tomography activation study using fluorine-18 fluorodeoxyglucose

    Energy Technology Data Exchange (ETDEWEB)

    Schreckenberger, M.; Sabri, O.; Arning, C.; Schulz, G.; Tuttass, T.; Wagenknecht, G.; Kaiser, H.J.; Buell, U. [Department of Nuclear Medicine, Aachen University of Technology, Aachen (Germany); Gouzoulis-Mayfrank, E.; Sass, H. [Department of Psychiatry, Aachen University of Technology, Aachen (Germany)

    1998-11-01

    Even though there have been numerous positron emission tomography (PET) activation studies on the perfusional and metabolic bases of language processing, little is known about the intracerebral functional network of language and cognitive processes. It was the aim of this study to investigate the cerebral interregional correlations during voluntary word association versus word repetition in healthy subjects to gain insight into the functional connectivity of associative speech processing. Due to individual variability in functional anatomy, the study protocol was designed as an averaged single-subject study. Eight healthy volunteers performed a verbal association task during fluorine-18 fluorodeoxyglucose ({sup 18}F-FDG) PET scanning. Two different tasks were performed in randomized order: (a) word repetition (after auditory presentation of nouns) as a control condition, and (b) word association (after auditory presentation of nouns) as a specific semantic activation. The regional metabolic rate of glucose (rMRGlu) was calculated after brain regionalization [112 regions of interest on individual 3D flash magnetic resonance imaging (MRI)] and PET/MRI realignment. Statistical analysis was performed for comparison of association and repetition and for calculation of interregional correlation coefficients during both tasks. Compared with word repetition, word association was associated with significant increases in rMRGlu in the left prefrontal cortex, the left frontal operculum (Broca`s area) and the left insula, indicating involvement of these areas in associative language processing. Decreased rMRGlu was found in the left posterior cingulum during word association. During word repetition, highly significant negative correlations were found between the left prefrontal cortex, the contralateral cortex areas and the ipsilateral posterior cingulum. These negative correlations were almost completely eliminated during the association task, suggesting a functional

  8. Intraregional and inter-regional variability of herbicide sensitivity in common arable weed populations

    DEFF Research Database (Denmark)

    de Mol, Friederike; Gerowitt, Bärbel; Kaczmarek, Sylwia

    2015-01-01

    The question on intraregional versus inter-regional variability in herbicide sensitivity for weed populations is of major importance, both in extrapolation of model parameters and in herbicide zonal approval procedures. We hypothesised that inter-regional variability in herbicide sensitivity...... for field populations would be the same as intraregional variability for regions with similar climatic conditions. Seeds of field weed populations were collected in a Danish, German and Polish region. Herbicide sensitivity was tested in dose–response experiments in the glasshouse with flufenacet...

  9. What does gamma coherence tell us about inter-regional neural communication?

    Science.gov (United States)

    Buzsáki, György; Schomburg, Erik W

    2015-04-01

    Neural oscillations have been measured and interpreted in multitudinous ways, with a variety of hypothesized functions in physiology, information processing and cognition. Much attention has been paid in recent years to gamma-band (30-100 Hz) oscillations and synchrony, with an increasing interest in 'high gamma' (>100 Hz) signals as mesoscopic measures of inter-regional communication. The biophysical origins of the measured variables are often difficult to precisely identify, however, making their interpretation fraught with pitfalls. Here we discuss how measurements of inter-regional gamma coherence can be prone to misinterpretation and suggest strategies for deciphering the roles that synchronized oscillations across brain networks may play in neural function.

  10. Reduced beta band connectivity during number estimation in autism

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    Katrin A. Bangel

    2014-01-01

    Full Text Available Recent evidence suggests that disruption of integrative processes in sensation and perception may play a critical role in cognitive and behavioural atypicalities characteristic of ASD. In line with this, ASD is associated with altered structural and functional brain connectivity and atypical patterns of inter-regional communication which have been proposed to contribute to cognitive difficulties prevalent in this group. The present MEG study used atlas-guided source space analysis of inter-regional phase synchronization in ASD participants, as well as matched typically developing controls, during a dot number estimation task. This task included stimuli with globally integrated forms (animal shapes as well as randomly-shaped stimuli which lacked a coherent global pattern. Early task-dependent increases in inter-regional phase synchrony in theta, alpha and beta frequency bands were observed. Reduced long-range beta-band phase synchronization was found in participants with ASD at 70–145 ms during presentation of globally coherent dot patterns. This early reduction in task-dependent inter-regional connectivity encompassed numerous areas including occipital, parietal, temporal, and frontal lobe regions. These results provide the first evidence for inter-regional phase synchronization during numerosity estimation, as well as its alteration in ASD, and suggest that problems with communication among brain areas may contribute to difficulties with integrative processes relevant to extraction of meaningful ‘Gestalt’ features in this population.

  11. On the Mutual Dynamics of Interregional Gross Migration Flows in Space and Time

    DEFF Research Database (Denmark)

    Mitze, Timo

    2016-01-01

    . Using a time-dynamic spatial Durbin model as preferred empirical specification, the results indicate that regional differences in real income growth, the labor participation rate and real-estate prices impact on interregional out-migration flows. The estimated coefficients signs of the obtained space...

  12. Spatial agglomeration and economic development with the inclusion of interregional tourism

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    Zhang Wei-Bin

    2017-01-01

    Full Text Available The purpose of this paper is to extend Uzawa’s two-sector model of a national economy to an economy with any number of regions and interregional tourism. The paper studies interregional economic development with interactions between wealth accumulation, economic structure, interregional trade and tourism under assumptions of profit maximization, utility maximization, and perfect competition. The model is unique in interregional neoclassical growth theory in that it introduces endogenous tourism within a general equilibrium framework. The model is built on microeconomic foundations. It not only extends the well-known Solow growth model and the Uzawa two-sector model to a national economy with any number of heterogeneous regional economies, but also introduces tourist flows between regions. We demonstrate that the movement of the J-regional economy can be described by J+1 differential equations. We simulate the movement of a national economy with three regions. We show that the dynamic system has a unique equilibrium. We carry out comparative dynamic analysis with regard to the propensity to tour a region, the cost of travel from one region to another, the total factor productivity of a region’s industrial sector, the total factor productivity of a region’s service sector, the propensity to save, the parameters of a region’s amenity, the propensity to consume housing, and the national population. We demonstrate the dynamic effects of these changes on national GDP, wealth, and tourist patterns.

  13. Inter-regional spillovers of seaports: the case of North-West Europe

    NARCIS (Netherlands)

    Merk, O.M.; Manshanden, W.J.J.; Dröes, M.I.

    2013-01-01

    This article describes the inter-regional spillover of seaports by assessing four large ports in Northwest Europe: Rotterdam, Antwerp, Hamburg and Le Havre. The authors disaggregate national input/output-tables to the level of the functional port area and calculate the relevant Leontief multipliers

  14. Interregional migration and housing structure in an East European transition country

    DEFF Research Database (Denmark)

    Bloze, Gintautas

    2009-01-01

    Abstract: This paper explores the relationship between interregional mobility at the municipality level and the local housing structure in a country where the housing sector is characterised by a relatively high private ownership rate, a small private rental sector and persistent undersupply of n...

  15. Diagnosis of autism spectrum disorders using regional and interregional morphological features.

    Science.gov (United States)

    Wee, Chong-Yaw; Wang, Li; Shi, Feng; Yap, Pew-Thian; Shen, Dinggang

    2014-07-01

    This article describes a novel approach to identify autism spectrum disorder (ASD) utilizing regional and interregional morphological patterns extracted from structural magnetic resonance images. Two types of features are extracted to characterize the morphological patterns: (1) Regional features, which includes the cortical thickness, volumes of cortical gray matter, and cortical-associated white matter regions, and several subcortical structures extracted from different regions-of-interest (ROIs); (2) Interregional features, which convey the morphological change pattern between pairs of ROIs. We demonstrate that the integration of regional and interregional features via multi-kernel learning technique can significantly improve the classification performance of ASD, compared with using either regional or interregional features alone. Specifically, the proposed framework achieves an accuracy of 96.27% and an area of 0.9952 under the receiver operating characteristic curve, indicating excellent diagnostic power and generalizability. The best performance is achieved when both feature types are weighted approximately equal, indicating complementary between these two feature types. Regions that contributed the most to classification are in line with those reported in the previous studies, particularly the subcortical structures that are highly associated with human emotional modulation and memory formation. The autistic brains demonstrate a significant rightward asymmetry pattern particularly in the auditory language areas. These findings are in agreement with the fact that ASD is a behavioral- and language-related neurodevelopmental disorder. By concurrent consideration of both regional and interregional features, the current work presents an effective means for better characterization of neurobiological underpinnings of ASD that facilitates its identification from typically developing children.

  16. Temperature-base and soma thermal for Zinnia ‘Profusion Cherry’ potted grown in protected environment

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    Charleston Gonçalves

    2016-02-01

    Full Text Available The growing of consumer market demands introduction of new species of flowers and cultivars primarily for production under protected cultivation. The zinnia by the quickness of production can be regarded as an alternative, however demand studies by the lack of information in the literature. We evaluated the duration of different periods, the base temperature and thermal accumulation, expressed as degree-days for the potted zinnia ‘Profusion Cherry’, conducted under protected cultivation for different phenological subperiods. The test was conducted in a greenhouse covered with plastic and closed laterally with shading-net and the duration of subperiods were made to twenty times after sowing. The base temperature was determined by relative development and values-based temperature and thermal time in degree-days (DD. The results for the different phases were, respectively: first open flower-planting: 4.1 °C and GD 838, first open flower - 50% of flowers open: 3.0 °C and 184 GD and 50% of flowers open - senescence: 6.9 °C and 238 GD.

  17. Social, economic and demographic factors relating to interregional migration in the Philippines: 1970-1980.

    Science.gov (United States)

    Llasa, R N

    1982-10-01

    The study attempts to identify the different social, economic, and demographic factors relating to interregional migration in the Philippines for the decade 1970-1980. The dependent variable used is the regional net migration rate estimated through the national growth rate method. Using the rank order correlation technique, the relationship between the dependent variable and the different independent variables were determined. It is found that the following variables were positively related to interregional migration: percentage of 20-29 year old population, previous in-migrants, median family income, land area, primacy index, level of urbanization, level of education, and percentage of never married population. However, the first 3 variables mentioned seem to be the most significant determinants of regional net migration rates, which indicates that net migration in the Philippines during the last decade tends to be more dependent upon previous migration patterns and less dependent upon current socioeconomic development.

  18. The soluble ectodomain of herpes simplex virus gD contains a membrane-proximal pro-fusion domain and suffices to mediate virus entry.

    Science.gov (United States)

    Cocchi, Francesca; Fusco, Daniela; Menotti, Laura; Gianni, Tatiana; Eisenberg, Roselyn J; Cohen, Gary H; Campadelli-Fiume, Gabriella

    2004-05-11

    Entry of herpes simplex virus (HSV) 1 into cells requires the interaction of HSV gD with herpesvirus entry mediator or nectin1 receptors, and fusion with cell membrane mediated by the fusion glycoproteins gB, gH, and gL. We report that the gD ectodomain in soluble form (amino acids 1-305) was sufficient to rescue the infectivity of a gD-null HSV mutant, indicating that gD does not need to be anchored to the virion envelope to mediate entry. Entry mediated by soluble gD required, in addition to the receptor-binding sites contained within residues 1-250, a discrete downstream portion (amino acids 261-305), located proximal to the transmembrane segment in full-length gD. We named it as profusion domain. The pro-fusion domain was required for entry mediated by virion-bound gD, because its substitution with the corresponding region of CD8 failed to complement the infectivity of gD(-/+) HSV. Furthermore, a receptor-negative gD (gD(Delta6-259)) inhibited virus infectivity when coexpressed with wild-type gD; i.e., it acted as a dominant-negative gD mutant. The pro-fusion domain is proline-rich, which is characteristic of regions involved in protein-protein interactions. P291L-P292A substitutions diminished the gD capacity to complement gD(-/+) HSV infectivity. We propose that gD forms a tripartite complex with its receptor and, by way of the proline-rich pro-fusion domain, with the fusion glycoproteins, or with one of them. The tripartite complex would serve to recruit/activate the fusion glycoproteins and bring them from a fusion-inactive to a fusion-active state, such that they execute fusion of the virion envelope with cell membrane.

  19. Diagnosis of Autism Spectrum Disorders Using Regional and Interregional Morphological Features

    OpenAIRE

    Wee, Chong-Yaw; Wang, Li; Shi, Feng; Yap, Pew-Thian; Shen, Dinggang

    2013-01-01

    This article describes a novel approach to identify autism spectrum disorder (ASD) utilizing regional and interregional morphological patterns extracted from structural magnetic resonance images. Two types of features are extracted to characterize the morphological patterns: (1) Regional features, which includes the cortical thickness, volumes of cortical gray matter, and cortical-associated white matter regions, and several subcortical structures extracted from different regions-of-interest ...

  20. What does gamma coherence tell us about inter-regional neural communication?

    OpenAIRE

    Buzsáki, György; Schomburg, Erik W

    2015-01-01

    Neural oscillations have been measured and interpreted in multitudinous ways, with a variety of hypothesized functions in physiology, information processing and cognition. Much attention has been paid in recent years to gamma-band (30–100 Hz) oscillations and synchrony, with an increasing interest in ‘high gamma’ (>100 Hz) signals as mesoscopic measures of inter-regional communication. The biophysical origins of the measured variables are often difficult to precisely identify, however, making...

  1. Interregional Cooperation Within Integration Processes in the Union State of Russia and Belarus

    Directory of Open Access Journals (Sweden)

    Ruslan Agarunovich Abramov

    2016-12-01

    Full Text Available The article deals with interregional cooperation of the Russian Federation and the Republic of Belarus in the spheres of trade, investment, industrial cooperation, education, science, culture, medicine and travel industry as a part of forming of The Eurasian Economic Space. Basing of the analysis of Russian and Belarusian regions’ experience the authors reveal the main problems of such cooperation. For example, it is shown that the major obstacle to making contacts between regions of the Union State is imperfection of federative and unitary structure, so there’s a need to enhance the role of supranational institutions and mechanisms for determining the interregional policy. It is proved that current contacts are geographically diversified. The authors give their recommendations to develop foundations for cooperation in innovative sector of economy. Identified prospects of development of interregional cooperation can be applied to the activities of legislative and executive authorities of the Union State as well as governmental bodies of Russian and Belarusian regions for maximizing their investment potential

  2. An elementary simulation model of the job matching process within an interregional setting.

    Science.gov (United States)

    Amrhein, C G; Mackinnon, R D

    1984-01-01

    Using a dynamic multiregional model, this paper discusses the job search and migration process and how they are affected by welfare levels, regional wage scales, and stress. This model relaxes the homogeneity assumptions; therefore, different skills and skill requirements exist. Despite the obvious importance of wages to both the worker and employer, the model assigns workers to jobs without regard to the wage paid; the objective function maximizes society's benefits rather than that of either the worker or the employer in isolation. 2 extreme salary distributions are used: 1) salaries are depressed to the point where the marginal worker receives a salary approaching zero; and 2) the employees control the gaming process and thus accept only high salaries. The interregional model assumes 2 types of people exist--movers and stayers. Migration occurs in response to a difference between a person's current level of utility and that level thought to be obtainable in another region. Proximal regions with lower stress values will reduce flows to more attractive, distant regions. An optimal interregional matching requires workers to engage in an interregional search for better opportunities; welfare levels and regional wage scales are determined. Welfare differentials perceived by the workers give rise to stress, and migration occurs if the experienced level of stress is greater than the perceived risk. Despite some limitations, the basic model formulated here produces reasonable results and further study is warranted. The introduction of the game theoretic formulation of the labor market into the geography literature provides a new and potentially important way to study labor migration.

  3. Different neural manifestations of two slow frequency bands in resting functional magnetic resonance imaging: a systemic survey at regional, interregional, and network levels.

    Science.gov (United States)

    Xue, Shao-Wei; Li, Da; Weng, Xu-Chu; Northoff, Georg; Li, Dian-Wen

    2014-05-01

    Temporal and spectral perspectives are two fundamental facets in deciphering fluctuating signals. In resting state, the dynamics of blood oxygen level-dependent (BOLD) signals recorded by functional magnetic resonance imaging (fMRI) have been proven to be strikingly informative (0.01-0.1 Hz). The distinction between slow-4 (0.027-0.073 Hz) and slow-5 (0.01-0.027 Hz) has been described, but the pertinent data have never been systematically investigated. This study used fMRI to measure spontaneous brain activity and to explore the different spectral characteristics of slow-4 and slow-5 at regional, interregional, and network levels, respectively assessed by regional homogeneity (ReHo) and mean amplitude of low-frequency fluctuation (mALFF), functional connectivity (FC) patterns, and graph theory. Results of paired t-tests supported/replicated recent research dividing low-frequency BOLD fluctuation into slow-4 and slow-5 for ReHo and mALFF. Interregional analyses showed that for brain regions reaching statistical significance, FC strengths at slow-4 were always weaker than those at slow-5. Community detection algorithm was applied to FC data and unveiled two modules sensitive to frequency effects: one comprised sensorimotor structure, and the other encompassed limbic/paralimbic system. Graph theoretical analysis verified that slow-4 and slow-5 differed in local segregation measures. Although the manifestation of frequency differences seemed complicated, the associated brain regions can be grossly categorized into limbic/paralimbic, midline, and sensorimotor systems. Our results suggest that future resting fMRI research addressing the three above systems either from neuropsychiatric or psychological perspectives may consider using spectrum-specific analytical strategies.

  4. Fiscal decentralization in the Italian NHS: what happens to interregional redistribution?

    Science.gov (United States)

    Ferrario, Caterina; Zanardi, Alberto

    2011-04-01

    This paper explores how pressures for an increased decentralization of taxing powers to sub-national governments may affect the degree of income redistribution across regional territories accomplished by the Italian NHS. In Italy, political responsibilities for health care are decentralized to regional governments, but the central government retains a critical role in ensuring all citizens uniform access to health services. To this end the central government runs an expenditure needs equalizing system to top up regional governments own resources. However, this system is currently put under question by strong political pressures calling for a weakening of central government involvement. Applying a well developed econometric approach we find that the NHS currently reduces interregional differences in per-capita income by about 7% of GDP. A reform of the NHS in terms of a reduction of expenditure standards produces a weakening of redistribution across jurisdictions, the size of which crucially depends on the financing arrangements of health care that will be actually adopted. We conclude that the decentralization of the NHS would give rise to relevant policy issues concerning in particular the different health care spending possibilities across regions and the impact on the interregional mobility of patients. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  5. Interregional correlation as exemplified by determining age of Permian suites of the Pechora coal basin

    Energy Technology Data Exchange (ETDEWEB)

    Gorskii, V.P.; Guseva, E.A.

    1986-04-01

    Using several different methods, age was estimated of several suites of Pechora coals located on northern part of Pre-Ural basin where the strato-type of the Permski system is found. Results of correlation of upper parts of Talatinski suite and all of Lekvorkutski with stratotypical sections of Central Pre-Ural demonstrate the Kungurski age of this part of the section, and confirm the expediency of including the Saraninski horizon in the composition of the Kungurski age, without which the border between the Artinski and Kungurski stages cannot be found as an isochronic level for any significant distance. The examined example indicates that results of interregional correlation proved to be essential factors in determining the volume of stratigraphic divisions (in the given example of Artinski and Kungurski stages). Question whether it is necessary to transfer border between sections of the Permski system to the base of the Saraninski horizon, i.e., the base of the Kungurski stage, must be decided separately on the basis of broader factual material in the order of a general revision of the entire scale of the Permski system. On the basis of the example, it is possible to conclude that the definiteness and volume of stratotype of general stratigraphic division in process of stratigraphic correlation and dependence of this volume on results of interregional correlation are a dialectic unity of two contradictory tendencies which depending on circumstances appear now in the role of argument, now of function. 16 references.

  6. Explore Interregional EEG Correlations Changed by Sport Training Using Feature Selection.

    Science.gov (United States)

    Gao, Jia; Wang, Wei; Zhang, Ji

    2016-01-01

    This paper investigated the interregional correlation changed by sport training through electroencephalography (EEG) signals using the techniques of classification and feature selection. The EEG data are obtained from students with long-time professional sport training and normal students without sport training as baseline. Every channel of the 19-channel EEG signals is considered as a node in the brain network and Pearson Correlation Coefficients are calculated between every two nodes as the new features of EEG signals. Then, the Partial Least Square (PLS) is used to select the top 10 most varied features and Pearson Correlation Coefficients of selected features are compared to show the difference of two groups. Result shows that the classification accuracy of two groups is improved from 88.13% by the method using measurement of EEG overall energy to 97.19% by the method using EEG correlation measurement. Furthermore, the features selected reveal that the most important interregional EEG correlation changed by training is the correlation between left inferior frontal and left middle temporal with a decreased value.

  7. Resting metabolic connectivity in prodromal Alzheimer's disease. A European Alzheimer Disease Consortium (EADC) project

    NARCIS (Netherlands)

    Morbelli, S.; Drzezga, A.; Perneczky, R.; Frisoni, G. B.; Caroli, A.; van Berckel, B.N.M.; Ossenkoppele, R.; Guedj, E.; Didic, M.; Brugnolo, A.; Sambuceti, G.; Pagani, M.; Salmon, E.; Nobili, F.

    2012-01-01

    We explored resting-state metabolic connectivity in prodromal Alzheimer's disease (pAD) patients and in healthy controls (CTR), through a voxel-wise interregional correlation analysis of 18F-fluorodeoxyglucose (FDG)-positron emission tomography (PET) by means of statistical parametric mapping.

  8. Numerical exploration of Kaldorian interregional macrodynamics: stability and the trade threshold for business cycles under fixed exchange rates.

    Science.gov (United States)

    Asada, Toichiro; Douskos, Christos; Markellos, Panagiotis

    2011-01-01

    The stability of equilibrium and the possibility of generation of business cycles in a discrete interregional Kaldorian macrodynamic model with fixed exchange rates are explored using numerical methods. One of the aims is to illustrate the feasibility and effectiveness of the numerical approach for dynamical systems of moderately high dimensionality and several parameters. The model considered is five-dimensional with four parameters, the speeds of adjustment of the goods markets and the degrees of economic interactions between the regions through trade and capital movement. Using a grid search method for the determination of the region of stability of equilibrium in two-dimensional parameter subspaces, and coefficient criteria for the flip bifurcation - and Hopf bifurcation - curve, we determine the stability region in several parameter ranges and identify Hopf bifurcation curves when they exist. It is found that interregional cycles emerge only for sufficient interregional trade. The relevant threshold is predicted by the model at 14 - 16 % of trade transactions. By contrast, no minimum level of capital mobility exists in a global sense as a requirement for the emergence of interregional cycles; the main conclusion being, therefore, that cycles may occur for very low levels of capital mobility if trade is sufficient. Examples of bifurcation and Lyapunov exponent diagrams illustrating the occurrence of cycles or period doubling, and examples of the development of the occurring cycles, are given. Both supercritical and subcritical bifurcations are found to occur, the latter type indicating coexistence of a point and a cyclical attractor.

  9. A comparison of the technological, economic, public policy, and environmental factors of HVDC and HVAC interregional transmission

    Directory of Open Access Journals (Sweden)

    Armando L. Figueroa-Acevedo

    2015-02-01

    Full Text Available The design of an interregional high-voltage transmission system in the US is a revolutionary technological concept that will likely play a significant role in the planning and operation of future electric power systems. Historically, the primary justification for building interregional high-voltage transmission lines in the US and around the world has been based on economic and reliability criteria. Today, the implementation renewable portfolio standards, carbon emission regulations, the improvements in the performance of power electronic systems, and unused benefits associated with capacity exchange during times of non-coincident peak demand, are driving the idea of designing an interregional high-voltage transmission system in the US. However, there exist challenges related to technical, economic, public policy, and environmental factors that hinder the implementation of such a complex infrastructure. The natural skepticism from many sectors of the society, in regards to how will the system be operated, how much will it cost, and the environmental impact that it could potentially create are among the most significant challenges to its rapid implementation. This publication aims at illustrating the technological, environmental, economic, and policy challenges that interregional HV transmission systems face today in the US, looking specifically at the Clean Line Rock Island project in Iowa.

  10. Modelos de desarrollo y convergencia interregional de la productividad industrial en Colombia

    Directory of Open Access Journals (Sweden)

    Jorge Lotero,

    2000-07-01

    Full Text Available Este trabajo tiene como propósito principal analizar fenómenos de convergencia o divergencia de la productividad laboral de la industria manufacturera de los departamentos colombianos y su relación con los modelos de desarrollo y con algunos de los llamados “atributos geográficos”. Poco ortodoxo en cuanto a sus objetivos, ya que tradicionalmente el análisis empírico de este tipo de fenómenos se ha limitado a observar el comportamiento interregional del ingreso per cápita, el trabajo explora tales relaciones utilizando técnicas sencillas de regresión y la ecuación general de convergencia.

  11. The effect of intra- and interregional labour mobility on plant performance in Denmark

    DEFF Research Database (Denmark)

    Timmermans, Bram; Boschma, Ron

    2014-01-01

    This article investigates the impact of labour mobility on plant performance in Denmark. Our study shows that the effect of labour mobility can only be assessed when one accounts for the type of skills that flow into the plant and the degree to which these match the existing skills at the plant...... level. As expected, we found that the inflow of skills that are related to skills in the plant impacts positively on plant productivity growth, while inflows of skills that are similar to the plant skills have a negative effect. We used a sophisticated indicator of revealed relatedness that measures...... the degree of skill relatedness between sectors on the basis of the intensity of labour flows between sectors. Intra-regional mobility of skilled labour had a negative effect on plant performance, but the impacts of intra- and inter-regional mobility depended on the type of skills that flow into the plant....

  12. Interregional migration of labor in Ghana, West Africa: determinants, consequences and policy intervention.

    Science.gov (United States)

    Arthur, J A

    1991-01-01

    Ghana is considered in examining the determinants, consequences, and policy intervention measures of the labor movement within a developing country's administrative regions. Data for the study come from the 1960-70 census and the 1975 intercensus. From the period of British colonial domination, far greater development effort has been focused upon the nation's coastal cities. Unevenly distributed development projects have favorably affected urban areas at the expense of rural regions. In turn, rural regions have become comparatively economically disadvantaged, with rural households and individuals looking to cities for economic advancement. While individuals may migrate to cities to escape family conflicts and obligations, in response to government economic policies or reductions in available family farm land, or out of a desire for adventure, the desire to maximize one's socioeconomic welfare underlies interregional migration. From rural-urban migration, rural areas benefit from both financial remittances of family members working in cities to extended rural families, and the technological contributions of returning migrants. Returning migrants may also contribute in developing community organizations and political awareness. On the negative side, however, rural areas lose their most physically capable workers, leading to lower production levels and changes to traditional gender roles. In cities, immigrants help fuel urban development, but also tax the supply of housing and the delivery of social services. Urban unemployment is high. The government feels that, on balance, interregional migration is negative, and should be checked. To this end, rural development policies and land settlement schemes have been implemented, albeit without much success. Program failure stems largely from the lack of a comprehensive national development effort.

  13. Inter-regional mating compatibility among Bactrocera dorsalis populations in Thailand (Diptera,Tephritidae)

    Science.gov (United States)

    Chinvinijkul, Suksom; Srikachar, Sunyanee; Kumjing, Phatchara; Weera Kimjong; Sukamnouyporn, Weerawan; Polchaimat, Nongon

    2015-01-01

    Abstract Mating compatibility among recently colonized (wildish) populations of Bactrocera dorsalis (Hendel) from different geographic origins in Thailand was assessed through inter-regional mating tests. Outdoor octagonal nylon screen field cages containing single potted mango trees (Mangifera indica L.) were used. Sexual compatibility was determined using the index of sexual isolation (ISI), the male relative performance index (MRPI), and the female relative performance index (FRPI). The ISI values indicated that the northern population of Bactrocera dorsalis from Chiang Mai province was sexually compatible with the southern population of Bactrocera dorsalis (previously Bactrocera papayae) from Nakhon Si Thammarat province. The MRPI values showed that the northern males had a slightly higher tendency to mate than southern males, while the FRPI data reflected that females of both origins participated equally in matings. In all combinations there were no differences between homotypic and heterotypic couples in mating latency. Southern males tended to mate first with southern females, followed by northern males mating with northern females, while the latest matings involved heterotypic couples, in particular northern males mating with southern females. Overall, more couples were collected from higher parts of the field cage and the upper tree canopy, while there were no differences between the origins of flies in terms of elevation of couples within the cage. Laboratory assessments of fecundity showed no differences in the average number of eggs resulting from inter-regional crosses. Development of immature stages was also equal in the two hybrid crosses, with no differences found in the number of pupae produced, percentage pupal recovery, and percent adult emergence. The practical implication of this study is that colony of Bactrocera dorsalis derived from any northern or southern region of Thailand can potentially be used in sterile insect technique programs

  14. Profuse color-evolution-based fluorescent test paper sensor for rapid and visual monitoring of endogenous Cu(2+) in human urine.

    Science.gov (United States)

    Cai, Yueqing; You, Junhui; You, Zhengyi; Dong, Fang; Du, Shuhu; Zhang, Liying

    2018-01-15

    The fluorescent paper for colorimetric detection of metal ions has been widely fabricated using various sensing probes, but it still remains an elusive task to design a test paper with multicolor variation with target dosages for accurate determination. Herein, we report a profuse color-evolution-based fluorescent test paper sensor for rapid and visual monitoring of Cu(2+) in human urine by printing tricolor probe onto filter paper. The tricolor probe consists of blue-emission carbon dots (bCDs), green-emission quantum dots (gQDs) and red-emission quantum dots (rQDs), which is based on the principle that the fluorescence of gQDs and rQDs are simultaneously quenched by Cu(2+), whereas the bCDs as the photostable internal standard is insensitive to Cu(2+). Upon the addition of different amounts of Cu(2+), the ratiometric fluorescence intensity of the tricolor probe continuously varied, leading to color changes from shallow pink to blue with a detection limit of 1.3nM. When the tricolor probe solution was printed onto a sheet of filter paper, as-obtained test paper displayed a more profuse color evolution from shallow pink to light salmon to dark orange to olive drab to dark olive green to slate blue to royal blue and to final dark blue with the increase of Cu(2+) concentration compared with dual-color probe-based test paper, and dosage scale as low as 6.0nM was clearly discriminated. The sensing test paper is simple, rapid and inexpensive, and serves as a visual platform for ultrasensitive monitoring of endogenous Cu(2+) in human urine. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Map-Based Cloning of Sbbmc, a Major Locus Controlling the Profuse Wax Trait of Sorghum: a Case Study in Unlocking the Abiotic Stress Tolerance of Sorghum bicolor via Integrated Physiological and Genomic Approaches

    Science.gov (United States)

    Sorghum bicolor is one of the most valuable “fail safe” cereal crop species and is a rich repository of genes for abiotic stress tolerance that await discovery. As an example, Sorghum exhibits cuticle which produces profuse amount of epicuticular wax (bloom) on sheaths and leaves that serves as key...

  16. Towards mapping the brain connectome in depression: functional connectivity by perfusion SPECT

    OpenAIRE

    Gardner, Ann; Åstrand, Disa; Öberg, Johanna; Jacobsson, Hans; Jonsson, Cathrine; Larsson, Stig; Pagani, Marco

    2014-01-01

    Several studies have demonstrated altered brain functional connectivity in the resting state in depression. However, no study investigated interregional networking in patients with persistent depressive disorder (PDD). The aim of this study was to assess differences in brain perfusion distribution and connectivity between large groups of patients and healthy controls. Participants comprised 91 patients with PDD and 65 age- and sex-matched healthy controls. Resting-state perfusion was investig...

  17. An interregional hedonic analysis of noxious facility impacts on local wages and property values

    Energy Technology Data Exchange (ETDEWEB)

    Clark, D.E.; Nieves, L.A.

    1991-01-01

    Claims of property value loss are commonly raised by homeowners when noxious facilities are sited or when new information about the hazards of existing facilities is made public. While the capitalization of externalities into land values is consistent with economic theory, empirical measurement of impacts has not generated consistent results. This is true both for hedonic measurements as well as other types of econometric analyses. While it is well established that job and site risks have similar impacts on regional labor markets, there are no studies relating the presence of a broad range of noxious facilities to local wage premiums. In contrast, this study employs an interregional framework in a hedonic analysis of both wage and property markets and considers eight different facility classifications. This paper discusses the development of the hedonic model employed in this study. It develops more fully the theoretical advantages of the intercity model and alternative methods of deriving implicit prices for environmental amenities and disamenities. The unique data base and the structure of the estimated model are described. It also includes a discussion of the research findings. Major conclusions and suggestions for further research are presented.

  18. Directions of development of road in terms of interregional integration in Russia

    Science.gov (United States)

    Seleznev, Alexander; Mottaeva, Angela; Andreeva, Larisa; Izmaylova, Svetlana

    2017-10-01

    The article is aimed at disclosure of the theoretical foundations of the development of transport infrastructure in the region. Sustainable transport and transport links allow to determine the direction of development of modern economy in the regions. Ensuring the availability of strategically important resources for many economic entities is one of the priorities of economic development of regions. the article presents the author’s approach to determination of perspective directions of development of relations of economic systems of regions and regional infrastructure. Important role in the processes of spatial integration of the regions transport infrastructure plays, which, on the one hand, determines the level of development of intra-regional production of goods and services, the availability of social welfare for the entire population, on the other hand, helps to establish strong intra-regional ties, thereby bringing together the socio-economic situation of neighbouring regions. Technological solutions for the transportation may be different in Russia, the developed network of Railways, efficiently functioning system of inter-regional pipelines, experiencing a rebirth water transport, however, a special place is occupied by road transportation.

  19. Interregional Partnership of Russia as a Tool of Realization of National Priorities of its Economic Development

    Directory of Open Access Journals (Sweden)

    E L Andreeva

    2015-12-01

    Full Text Available The analysis of interregional economic partnership existing simultaneously with the concept of traditional regionalism is proposed in the article. The cases of Trans-Pacific strategic economic partnership agreement (TPSEPA which is created already for some decades; Transpacific agreement on strategic and economic partnership plan (2012, under which the US and the EU are going to form a Transatlantic FTA (TAFTA; initiative of Asia and Pacific countries (presented at the summit of these countries in 2012 to form a Regional comprehensive economic partnership (RCEP are described. The case of BRICS is analyzed in details. The economic factors joining the countries - participants of the group are analyzed. The prospects of broadening of its partnership - with participation of economies of South America are highlighted. Russian external trade is touched by machinery production and accompanying services with the countries-partners mentioned. It’s shown that these economic relations can be used by Russia for solving of the tasks of substitution of import, neo-industrialization and export stimulating.

  20. Adherence to physical activity recommendations and its associated factors: an interregional population-based study

    Directory of Open Access Journals (Sweden)

    Ala'a Alkerwi

    2015-03-01

    Full Text Available Background. Though the influence of physical activity in preventing cardiovascular diseases is well documented, only a few comparative studies have determined the degree of adherence to physical activity recommendations among populations and identified the demographic, socioeconomic, behavioural and health-related factors associated with good compliance. Design and methods. Cross-sectional interregional NESCaV survey of 3133 subjects compared three populations, Luxembourg, Lorraine (France and Wallonia (Belgium, by using the International Physical Activity Questionnaire. Age and gender prevalence rates of physical activity were standardized to the European population. Results. The likelihood to meet the recommendations was higher in Luxembourg, after adjustment for age, gender, education, employment, weight status, morbidity score, health perception and level of importance attributed to the practice of physical activity (P<0.0001. The odds for meeting the recommendations were significantly higher among those with secondary than tertiary education. Compared to good self-health perception, subjects with poor or fair self-perceived health were less likely to meet the recommendations; this also applied to those attributing little or enough importance to physical activity compared with great importance. Conclusions. Region, education, self-perceived health and perception of importance of physical activity were emerged as independent determinants of meeting the recommendations. Awareness of the positive health effects of physical activity might thus be crucial for motivating the people to become more active. Further research is needed to explore potential region-specific factors which might explain the difference in population behaviours with respect to physical activity.

  1. An interregional hedonic analysis of noxious facility impacts on local wages and property values

    Energy Technology Data Exchange (ETDEWEB)

    Clark, D.E.; Nieves, L.A.

    1991-12-31

    Claims of property value loss are commonly raised by homeowners when noxious facilities are sited or when new information about the hazards of existing facilities is made public. While the capitalization of externalities into land values is consistent with economic theory, empirical measurement of impacts has not generated consistent results. This is true both for hedonic measurements as well as other types of econometric analyses. While it is well established that job and site risks have similar impacts on regional labor markets, there are no studies relating the presence of a broad range of noxious facilities to local wage premiums. In contrast, this study employs an interregional framework in a hedonic analysis of both wage and property markets and considers eight different facility classifications. This paper discusses the development of the hedonic model employed in this study. It develops more fully the theoretical advantages of the intercity model and alternative methods of deriving implicit prices for environmental amenities and disamenities. The unique data base and the structure of the estimated model are described. It also includes a discussion of the research findings. Major conclusions and suggestions for further research are presented.

  2. ASSESSMENT OF URBAN BUILT ENVIRONMENT QUALITY ON THE URBANIZED TERRITORIES: INTERREGIONAL COMPARISONS

    Directory of Open Access Journals (Sweden)

    Ovsiannikova T. Yu.

    2015-06-01

    Full Text Available The urbanization and growth of a cities role, formation of cities as reference points of regions economic development are modern global tendencies. Cities concentrate human and investment resources on their territory, so in large part cities cause competitiveness of the regions in the global market. For preservation of competitive advantages regions need to form on the urbanized territories not only the favorable environment for business, but also for the population life. This paper deals with the problem of an assessment of urban built environment quality, due to urban built environment is a space-material basis of life quality of the population on the urbanized territories. The role of the cities in social and economic development of regions and their considerable influence on competitiveness of territories in the global competition for economic resources are proved. The method of assessment of urban built environment quality on the basis of calculation of an integrated index is proposed. Interregional comparisons on the example of regions of the Siberian and Ural Federal districts are completed. The offered method of assessment of urban built environment quality allows to range the urbanized territories on usefulness for living, to reveal most and the least developed spheres of city infrastructure.

  3. [Evolution and follow-up of hunger strikers: experience from an interregional hospital secured unit].

    Science.gov (United States)

    Dubois, F; Sudre, E; Porte, A; Bédry, R; Gromb, S

    2011-11-01

    A hunger strike is a voluntary fast, performed to protest publicly against an issue deemed unfair. In the case of French prisoners, hospitalization in an interregional hospital secured units (UHSI) may be necessary. A retrospective epidemiological study based on one UHSI medical records was performed on the period of May, 2006 to December, 2008, and focused on symptoms, outcomes and ethical problems encountered. Seven men and one woman with a mean age of 32.6 years were hospitalized in an UHSI, with nine episodes of hunger strike of a median duration of 57 days. Clinical symptoms began after two weeks of voluntary deprivation in the form of dizziness, weakness, muscle pain and headache. Laboratory tests showed hypoglycemia (daily basis. The special problem encountered in the medical management of these strikers was to convince them to accept treatments in order to avoid a coercive life-saving treatment as requested by French law. Copyright © 2011 Société nationale française de médecine interne (SNFMI). Published by Elsevier SAS. All rights reserved.

  4. Differential auxin transport and accumulation in the stem base lead to profuse adventitious root primordia formation in the aerial roots (aer) mutant of tomato (Solanum lycopersicum L.).

    Science.gov (United States)

    Mignolli, F; Mariotti, L; Picciarelli, P; Vidoz, M L

    2017-06-01

    The aerial roots (aer) mutant of tomato is characterized by a profuse and precocious formation of adventitious root primordia along the stem. We demonstrated that auxin is involved in the aer phenotype but ruled out higher auxin sensitivity of mutant plants. Interestingly, polar auxin transport was altered in aer, as young seedlings showed a reduced response to an auxin transport inhibitor and higher expression of auxin export carriers SlPIN1 and SlPIN3. An abrupt reduction in transcripts of auxin efflux and influx genes in older aer hypocotyls caused a marked deceleration of auxin transport in more mature tissues. Indeed, in 20days old aer plants, the transport of labeled IAA was faster in apices than in hypocotyls, displaying an opposite trend in comparison to a wild type. In addition, auxin transport facilitators (SlPIN1, SlPIN4, SlLAX5) were more expressed in aer apices than in hypocotyls, suggesting that auxin moves faster from the upper to the lower part of the stem. Consequently, a significantly higher level of free and conjugated IAA was found at the base of aer stems with respect to their apices. This auxin accumulation is likely the cause of the aer phenotype. Copyright © 2017 Elsevier GmbH. All rights reserved.

  5. Characterizing 40-years of inter-regional migration in Southern Mauritania as a result of environmental changes

    Science.gov (United States)

    Salam El Vilaly, Mohamed Abd; El Vilaly, Audra; Mahe, Gil

    2017-04-01

    Formerly a country of nomadism par excellence, Mauritania has experienced since its independence in 1960 a spectacular sedentarisation of its nomadic population. In fact, nomads have decreased from 75% of the total population in 1965 to 12 % in 1988, and just 6% in 2000. This rapid and unprecedented sedentarisation, particularly in Southern Mauritania, can be explained by several factors, including the devastating droughts in the 1970s and 1980s, as well as the turbulent transformation of Mauritania's political economy. Together, these factors have destabilized rural livelihoods and accelerated land degradation, livestock loss, urbanization, and conflict between farmers and herders over natural resources and water access across the area, resulting in unprecedented inter-regional migration. The aim of this 40- years study is not to review in detail all the factors driving inter-regional migration in Southern Mauritania, but instead to scrutinize at the relationship between vegetation productivity, land cover changes, rainfall trends, and dynamic spatial demographic shifts from 1971 to 2015. In this regard, we propose an advanced assessment approach that integrates demographic information, climatological data, and multi-sensor Normalized Difference Vegetation Index (NDVI) time series data from 1981 to 2015 at 5.6 km to characterize the inter-regional migration movements in Southern Mauritania. A multi-linear regression analysis was conducted to examine to which extent the inter-regional migration movements are controlled by both climate and environmental changes. The demographic data show that Southern Mauritania's population grew less rapidly at an annual rate between 1977 and 1988 than between 1988 and 2000. The annual growth rate recorded in 2000 was 2.9%, compared to 2.5% in 1988 and 2.29% in 1960. Moreover, the population sedentarized dramatically at a rate of 95.2% in 2000 compared to 84.4% in 1988. The results also show distinctive interactions between

  6. Inter-regional changes in the performance and interpretation of spirometry in Spain: 3E study.

    Science.gov (United States)

    López-Campos, José Luis; Soriano, Joan B; Calle, Myriam

    2014-11-01

    This report shows the results of a nation-wide survey on spirometry to assess regional differences. Observational cross-sectional study conducted by means of a telephone survey in 805 primary care (PC) and specialized centers (SC) in all regions. The survey contacted technicians in charge of spirometry and consisted of 36 questions related to the test. The results showed major differences between regions. Most centers had 1-2 spirometers. The number of spirometry tests per week ranged from 2 to 8.9 in PC and between 34.3 and 98.3 in SC. Some training had been given in most centers (63.6-100% in PC and 60.0-100% in SC) but not on a regular basis. Most centers used several short-acting bronchodilators for the bronchodilation test, but with insufficient inhalations (2.0-3.8 in PC and 2.0-3.3 in SC) and frequently incorrect waiting time (29.4-83.3% PC and 33.3-87.5% in SC). Daily calibration was not performed in all centers (0-100% in PC and 66.7-100% in SC). Significant inter-regional differences in spirometry quality criteria were observed, with 6 or more criteria met in 9.1-84.6% of PC centers and 37.5-100% in SC. Our results show the current situation of spirometry in primary and specialized care in Spain, highlighting considerable variability and areas for improvement. This information should be considered by health officials to improve the quality and accessibility of such tests. Copyright © 2014 SEPAR. Published by Elsevier Espana. All rights reserved.

  7. Cardiovascular mortality associated with low and high temperatures: determinants of inter-region vulnerability in China.

    Science.gov (United States)

    Yang, Xunfeng; Li, Lianfa; Wang, Jinfeng; Huang, Jixia; Lu, Shijun

    2015-05-27

    The objectives of this study were to estimate the effects of temperature on cardiovascular mortality in 26 regions in the south and west of China from 2008 to 2011, and to identify socioeconomic and demographic factors contributing to such inter-region variation in the temperature effect. A separate Poisson generalized additive model (GAM) was fitted to estimate percent changes in cardiovascular mortality at low and high temperatures on a daily basis for each region. The model used the smooth functions to model the nonlinear effects of temperature and humidity and to control for the seasonal factor using the calendar time variable. Given variation in the magnitude of the temperature effect on cardiovascular mortality, we employed a Bayesian network (BN) to identify potential region-specific socioeconomic and demographic factors that may explain the variation. In most regions, an increasing trend in high or low temperature was associated with an increase in cardiovascular mortality, with variation in the magnitude of the temperature effects across regions. Three factors, including per capita years of education (as an indicator of economic status), percentage of the population over 65 years of age and percentage of women had direct impact on cold-related cardiovascular mortality. Number of hospital beds (as an indicator of the availability of medical resources), percentage of population engaged in industrial occupations, and percentage of women showed direct impact on heat-related cardiovascular mortality. Due to the socioeconomic and demographic inequalities between regions, the development of customized prevention and adaptation programs to address the low/high temperatures in vulnerable regions should be prioritized.

  8. A multi-stream analysis of the changing pattern of interregional migration in Great Britain, 1960-1991.

    Science.gov (United States)

    Gordon, I R; Molho, I

    1998-06-01

    "This paper uses a combination of spatial and econometric modelling techniques to investigate longer term patterns and processes of change in British interregional migration.... The two major influences on the longer distance flows are found to be relative rates of employment growth and perceived environmental quality, but while the former induces marked fluctuations within the observation period, the influence of the latter factors shows little variation, with no sign of a clean break. There is, however, evidence of a sharply reduced responsiveness of migration to unemployment differentials since the mid-1970s." (EXCERPT)

  9. Interregional Coevolution Analysis Revealing Functional and Structural Interrelatedness between Different Genomic Regions in Human Mastadenovirus D.

    Science.gov (United States)

    Gonzalez, Gabriel; Koyanagi, Kanako O; Aoki, Koki; Watanabe, Hidemi

    2015-06-01

    Human mastadenovirus D (HAdV-D) is exceptionally rich in type among the seven human adenovirus species. This feature is attributed to frequent intertypic recombination events that have reshuffled orthologous genomic regions between different HAdV-D types. However, this trend appears to be paradoxical, as it has been demonstrated that the replacement of some of the interacting proteins for a specific function with other orthologues causes malfunction, indicating that intertypic recombination events may be deleterious. In order to understand why the paradoxical trend has been possible in HAdV-D evolution, we conducted an interregional coevolution analysis between different genomic regions of 45 different HAdV-D types and found that ca. 70% of the genome has coevolved, even though these are fragmented into several pieces via short intertypic recombination hot spot regions. Since it is statistically and biologically unlikely that all of the coevolving fragments have synchronously recombined between different genomes, it is probable that these regions have stayed in their original genomes during evolution as a platform for frequent intertypic recombination events in limited regions. It is also unlikely that the same genomic regions have remained almost untouched during frequent recombination events, independently, in all different types, by chance. In addition, the coevolving regions contain the coding regions of physically interacting proteins for important functions. Therefore, the coevolution of these regions should be attributed at least in part to natural selection due to common biological constraints operating on all types, including protein-protein interactions for essential functions. Our results predict additional unknown protein interactions. Human mastadenovirus D, an exceptionally type-rich human adenovirus species and causative agent of different diseases in a wide variety of tissues, including that of ocular region and digestive tract, as well as an

  10. Inter-regional comparison of land-use effects on stream metabolism

    Science.gov (United States)

    Bernot, M.J.; Sobota, D.J.; Hall, R.O.; Mulholland, P.J.; Dodds, W.K.; Webster, J.R.; Tank, J.L.; Ashkenas, L.R.; Cooper, L.W.; Dahm, Clifford N.; Gregory, S.V.; Grimm, N. B.; Hamilton, S.K.; Johnson, S.L.; McDowell, W.H.; Meyer, J.L.; Peterson, B.; Poole, G.C.; Maurice, Valett H.M.; Arango, C.; Beaulieu, J.J.; Burgin, A.J.; Crenshaw, C.; Helton, A.M.; Johnson, L.; Merriam, J.; Niederlehner, B.R.; O'Brien, J. M.; Potter, J.D.; Sheibley, R.W.; Thomas, S.M.; Wilson, K.

    2010-01-01

    control pathways including a direct effect of land-use on GPP as well as SRP, DIN, and PAR effects on GPP; GPP effects on autotrophic biomass, organic matter, and ER; and organic matter effects on ER.6. Overall, consideration of the data separated by land-use categories showed reduced inter-regional variability in rates of metabolism, indicating that the influence of agricultural and urban land use can obscure regional differences in stream metabolism. ?? 2010 Blackwell Publishing Ltd.

  11. The functional connectivity landscape of the human brain.

    Directory of Open Access Journals (Sweden)

    Bratislav Mišić

    Full Text Available Functional brain networks emerge and dissipate over a primarily static anatomical foundation. The dynamic basis of these networks is inter-regional communication involving local and distal regions. It is assumed that inter-regional distances play a pivotal role in modulating network dynamics. Using three different neuroimaging modalities, 6 datasets were evaluated to determine whether experimental manipulations asymmetrically affect functional relationships based on the distance between brain regions in human participants. Contrary to previous assumptions, here we show that short- and long-range connections are equally likely to strengthen or weaken in response to task demands. Additionally, connections between homotopic areas are the most stable and less likely to change compared to any other type of connection. Our results point to a functional connectivity landscape characterized by fluid transitions between local specialization and global integration. This ability to mediate functional properties irrespective of spatial distance may engender a diverse repertoire of cognitive processes when faced with a dynamic environment.

  12. Hyperthermia-induced disruption of functional connectivity in the human brain network.

    Directory of Open Access Journals (Sweden)

    Gang Sun

    Full Text Available BACKGROUND: Passive hyperthermia is a potential risk factor to human cognitive performance and work behavior in many extreme work environments. Previous studies have demonstrated significant effects of passive hyperthermia on human cognitive performance and work behavior. However, there is a lack of a clear understanding of the exact affected brain regions and inter-regional connectivities. METHODOLOGY AND PRINCIPAL FINDINGS: We simulated 1 hour environmental heat exposure to thirty-six participants under two environmental temperature conditions (25 °C and 50 °C, and collected resting-state functional brain activity. The functional connectivities with a preselected region of interest (ROI in the posterior cingulate cortex and precuneus (PCC/PCu, furthermore, inter-regional connectivities throughout the entire brain using a prior Anatomical Automatic Labeling (AAL atlas were calculated. We identified decreased correlations of a set of regions with the PCC/PCu, including the medial orbitofrontal cortex (mOFC and bilateral medial temporal cortex, as well as increased correlations with the partial orbitofrontal cortex particularly in the bilateral orbital superior frontal gyrus. Compared with the normal control (NC group, the hyperthermia (HT group showed 65 disturbed functional connectivities with 50 of them being decreased and 15 of them being increased. While the decreased correlations mainly involved with the mOFC, temporal lobe and occipital lobe, increased correlations were mainly located within the limbic system. In consideration of physiological system changes, we explored the correlations of the number of significantly altered inter-regional connectivities with differential rectal temperatures and weight loss, but failed to obtain significant correlations. More importantly, during the attention network test (ANT we found that the number of significantly altered functional connectivities was positively correlated with an increase in

  13. Analysis of socio-economic impacts of sustainable sugarcane-ethanol production by means of inter-regional Input-Output analysis: Demonstrated for Northeast Brazil

    NARCIS (Netherlands)

    Herreras Martinez, S.D.; van Eijck, J.A.J.|info:eu-repo/dai/nl/297954296; Pereira da Cunha, M.; Guilhote, J.J.M.; Walter, A.; Faaij, A.P.C.|info:eu-repo/dai/nl/10685903X

    2013-01-01

    This study assesses the socio-economic impacts in terms of value added, imports and employment of sugarcane-derived bioethanol production in Northeast (NE) Brazil. An extended inter-regional Input–Output (IO) model has been developed and is used to analyse three scenarios, all projected for 2020: a

  14. An Inter-regional US Blood Supply Simulation Model to Evaluate Blood Availability to Support Planning for Emergency Preparedness and Medical Countermeasures.

    Science.gov (United States)

    Simonetti, Arianna; Ezzeldin, Hussein; Walderhaug, Mark; Anderson, Steven A; Forshee, Richard A

    2017-08-23

    Planning for a response to threats like pandemics or mass casualty events is a national priority. The US blood supply system can be particularly vulnerable to such events. It is important to understand the impacts of emergency situations on blood availability and the resiliency of the US blood supply system. On the basis of the Stock-and-Flow simulation model of the US blood supply system, we developed an inter-regional blood transfer system representing the action of multiple blood collectors and distributors to enable effective planning of strategies to minimize collection and donation disruptions to the blood supply system in the event of a national emergency. We simulated a pandemic or mass casualty event on both a national and an inter-regional blood supply system. Differences in the estimated impacts demonstrated the importance of incorporating spatial and temporal variations of blood collection and utilization across US regions. The absence of blood shortage in both emergency scenarios highlighted the resilience of the inter-regional system to meet the potential associated blood demand. Our inter-regional model considered complex factors and can be a valuable tool to assist regulatory decision-making and strategic planning for emergency preparedness to avoid and mitigate associated adverse health consequences. (Disaster Med Public Health Preparedness. 2017;page 1 of 10).

  15. Trends in the inter-regional and international research collaboration of the PRC’s regions: 2000-2015

    Energy Technology Data Exchange (ETDEWEB)

    Luwel, M.; Van Wijk, E.; Van der Wurff, L.J.; Wang, L.

    2016-07-01

    The regional structure of the PRC’s scientific output is analyzed using publications processed for the Web of Science. Over the period 2000-2015 and measured by the Salton Index of the co-publications the scientific collaboration among the PRC’s regions increased only slightly, in stark contrast with the USA’ states and during the most recent years the EU member countries. Only for research with other nations, representing about 30% of the total publication output, inter-regional collaboration is on the rise. For the leading PRC’s regions the USA is the dominant partner co-authoring about 50% of their publications. Germany and especially Japan seems to lose attractiveness to the advantage of the UK, Australia and neighboring Asian countries. (Author)

  16. ASSESSMENT OF INTER-REGIONAL CONVERGENCE IN THE SOCIAL WELFARE BASED ON THE A. SEN FUNCTION: RUSSIAN CASE STUDY

    Directory of Open Access Journals (Sweden)

    Marina Malkina

    2017-03-01

    Full Text Available The aim of this study is estimation of social welfare in Russian regions in 2004-2014 based on the A. Sen abbreviated function, the assessment of regions convergence in welfare and factors contributing to it. We adjusted the A. Sen welfare function by the cost of living in regions and presented it as a four-factor multiplicative model. By use of the coefficient of variation (CV we estimated the inter-regional inequality in welfare in statics and dynamics. The technique of decomposition of the squared CV for logarithm of welfare function enabled us to evaluate the contribution of main and intersect factors to Russian regions' convergence in welfare. As a result we assessed Russian regions social welfare in dynamics and evaluated factors contributing to its growth. Based on the weighted CV we discovered the negative impact of the recession of 2009 on the regions convergence in welfare, and unweighted CV even more revealed the turning point in the convergence tendency occurring in 2012. We discovered that in statics the redistributive factor makes the greatest and increasing contribution to inter-regional convergence in welfare, whilst the cost of living and intraregional income inequality factors have moderate and decreasing influence on it. The dynamic analysis revealed two factors predominantly contributing to regions' temporal convergence in welfare, namely growing convergence in GRP per capita and significant but unstable influence of distributive factor. Two other factors, the cost of living and intra-regional income inequality, counteracted to temporal convergence mainly due to attenuation of their negative correlation to nominal and real income per capita respectively. The results obtained may be applicable to both inter-budgetary and regional policy development.

  17. Reduced theta connectivity during set-shifting in children with autism

    Directory of Open Access Journals (Sweden)

    Sam McLeod Doesburg

    2013-11-01

    Full Text Available Autism spectrum disorder (ASD is a characterized by deficits in social cognition and executive function. An area of particular difficulty for children with ASD is cognitive flexibility, such as the ability to shift between attentional or response sets. The biological basis of such deficits remains poorly understood, although atypical development of structural and functional brain connectivity have been reported in ASD, suggesting that disruptions of normal patterns of inter-regional communication may contribute to cognitive problems in this group. The present MEG study measured inter-regional phase synchronization while children with ASD and typically developing matched controls (6-14 years of age performed a set-shifting task. Reduced theta-band phase synchronization was observed in children with ASD during extradimensional set-shifting. This reduction in task-dependent inter-regional connectivity encompassed numerous areas including multiple frontal lobe regions, and indicates that problems with communication among brain areas may contribute to difficulties with executive function in ASD.

  18. Effective Connectivity between Ventral Occipito-Temporal and Ventral Inferior Frontal Cortex during Lexico-Semantic Processing. A Dynamic Causal Modeling Study

    Directory of Open Access Journals (Sweden)

    Marcela Perrone-Bertolotti

    2017-06-01

    Full Text Available It has been suggested that dorsal and ventral pathways support distinct aspects of language processing. Yet, the full extent of their involvement and their inter-regional connectivity in visual word recognition is still unknown. Studies suggest that they might reflect the dual-route model of reading, with the dorsal pathway more involved in grapho-phonological conversion during phonological tasks, and the ventral pathway performing lexico-semantic access during semantic tasks. Furthermore, this subdivision is also suggested at the level of the inferior frontal cortex, involving ventral and dorsal parts for lexico-semantic and phonological processing, respectively. In the present study, we assessed inter-regional brain connectivity and task-induced modulations of brain activity during a phoneme detection and semantic categorization tasks, using fMRI in healthy subject. We used a dynamic causal modeling approach to assess inter-regional connectivity and task demand modulation within the dorsal and ventral pathways, including the following network components: the ventral occipito-temporal cortex (vOTC; dorsal and ventral, the superior temporal gyrus (STG; dorsal, the dorsal inferior frontal gyrus (dIFG; dorsal, and the ventral IFG (vIFG; ventral. We report three distinct inter-regional interactions supporting orthographic information transfer from vOTC to other language regions (vOTC -> STG, vOTC -> vIFG and vOTC -> dIFG regardless of task demands. Moreover, we found that (a during semantic processing (direct ventral pathway the vOTC -> vIFG connection strength specifically increased and (b a lack of modulation of the vOTC -> dIFG connection strength by the task that could suggest a more general involvement of the dorsal pathway during visual word recognition. Results are discussed in terms of anatomo-functional connectivity of visual word recognition network.

  19. Replicability of time-varying connectivity patterns in large resting state fMRI samples.

    Science.gov (United States)

    Abrol, Anees; Damaraju, Eswar; Miller, Robyn L; Stephen, Julia M; Claus, Eric D; Mayer, Andrew R; Calhoun, Vince D

    2017-12-01

    The past few years have seen an emergence of approaches that leverage temporal changes in whole-brain patterns of functional connectivity (the chronnectome). In this chronnectome study, we investigate the replicability of the human brain's inter-regional coupling dynamics during rest by evaluating two different dynamic functional network connectivity (dFNC) analysis frameworks using 7 500 functional magnetic resonance imaging (fMRI) datasets. To quantify the extent to which the emergent functional connectivity (FC) patterns are reproducible, we characterize the temporal dynamics by deriving several summary measures across multiple large, independent age-matched samples. Reproducibility was demonstrated through the existence of basic connectivity patterns (FC states) amidst an ensemble of inter-regional connections. Furthermore, application of the methods to conservatively configured (statistically stationary, linear and Gaussian) surrogate datasets revealed that some of the studied state summary measures were indeed statistically significant and also suggested that this class of null model did not explain the fMRI data fully. This extensive testing of reproducibility of similarity statistics also suggests that the estimated FC states are robust against variation in data quality, analysis, grouping, and decomposition methods. We conclude that future investigations probing the functional and neurophysiological relevance of time-varying connectivity assume critical importance. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  20. The effect of inter-annual variability of consumption, production, trade and climate on crop-related green and blue water footprints and inter-regional virtual water trade: A study for China (1978-2008).

    Science.gov (United States)

    Zhuo, La; Mekonnen, Mesfin M; Hoekstra, Arjen Y

    2016-05-01

    Previous studies into the relation between human consumption and indirect water resources use have unveiled the remote connections in virtual water (VW) trade networks, which show how communities externalize their water footprint (WF) to places far beyond their own region, but little has been done to understand variability in time. This study quantifies the effect of inter-annual variability of consumption, production, trade and climate on WF and VW trade, using China over the period 1978-2008 as a case study. Evapotranspiration, crop yields and green and blue WFs of crops are estimated at a 5 × 5 arc-minute resolution for 22 crops, for each year in the study period, thus accounting for climate variability. The results show that crop yield improvements during the study period helped to reduce the national average WF of crop consumption per capita by 23%, with a decreasing contribution to the total from cereals and increasing contribution from oil crops. The total consumptive WFs of national crop consumption and crop production, however, grew by 6% and 7%, respectively. By 2008, 28% of total water consumption in crop fields in China served the production of crops for export to other regions and, on average, 35% of the crop-related WF of a Chinese consumer was outside its own province. Historically, the net VW within China was from the water-rich South to the water-scarce North, but intensifying North-to-South crop trade reversed the net VW flow since 2000, which amounted 6% of North's WF of crop production in 2008. South China thus gradually became dependent on food supply from the water-scarce North. Besides, during the whole study period, China's domestic inter-regional VW flows went dominantly from areas with a relatively large to areas with a relatively small blue WF per unit of crop, which in 2008 resulted in a trade-related blue water loss of 7% of the national total blue WF of crop production. The case of China shows that domestic trade, as governed by

  1. Connected Traveler

    Energy Technology Data Exchange (ETDEWEB)

    Schroeder, Alex

    2015-11-01

    The Connected Traveler project is a multi-disciplinary undertaking that seeks to validate potential for transformative transportation system energy savings by incentivizing efficient traveler behavior. This poster outlines various aspects of the Connected Traveler project, including market opportunity, understanding traveler behavior and decision-making, automation and connectivity, and a projected timeline for Connected Traveler's key milestones.

  2. Effective Connectivity Modeling for fMRI: Six Issues and Possible Solutions Using Linear Dynamic Systems

    Directory of Open Access Journals (Sweden)

    Jason Fitzgerald Smith

    2012-01-01

    Full Text Available Analysis of directionally specific or causal interactions between regions in functional magnetic resonance imaging (fMRI data has proliferated. Here we identify six issues with existing effective connectivity methods that need addressed. The issues are discussed within the framework of Linear Dynamic Systems for fMRI (LDSf. The first concerns the use of deterministic models to identify inter-regional effective connectivity. We show that deterministic dynamics are incapable of identifying the trial-to-trial variability typically investigated as the marker of connectivity while stochastic models can capture this variability. The second concerns the simplistic (constant connectivity modeled by most methods. Connectivity parameters of the LDSf model can vary at the same timescale as the input data. Further, extending LDSf to mixtures of multiple models provides more robust connectivity variation. The third concerns the correct identification of the network itself including the number and anatomical origin of the network nodes. Augmentation of the LDSf state space can identify additional nodes of a network. The fourth concerns the locus of the signal used as a node in a network. A novel extension LDSf incorporating sparse canonical correlations can select most relevant voxels from an anatomically defined region based on connectivity. The fifth concerns connection interpretation. Individual parameter differences have received most attention. We present alternative network descriptors of connectivity changes which consider the whole network. The sixth concerns the temporal resolution of fMRI data relative to the timescale of the inter-regional interactions in the brain. LDSf includes an instantaneous connection term to capture connectivity occurring at timescales faster than the data resolution. The LDS framework can also be extended to statistically combine fMRI and EEG data. The LDSf framework is a promising foundation for effective connectivity

  3. Economic Globalization and Interregional Agglomeration in a Multi-Country and Multi-Regional Neoclassical Growth Model

    Directory of Open Access Journals (Sweden)

    Wei-Bin Zhang

    2016-01-01

    Full Text Available El objetivo de este artículo es generalizar el conocido modelo de Uzawa de dos sectores para una economía nacional para su aplicación en contextos globales con muchos países y muchas regiones dentro de cada país. Se estudia el desarrollo económico internacional e interregional a través de un modelo de equilibrio general donde se considera la acumulación de riqueza, el intercambio de recursos y la estructura económica bajo los supuestos de maximización de beneficios y utilidad y competencia perfecta. Para ello se aplica el modelo alternativo de Zhang sobre el comportamiento de los hogares simulándolo para un contexto multi-país y multi-región en una economía global, identificando la existencia del equilibrio y confirmando la estabilidad del mismo. Adicionalmente, se realiza un análisis comparativo dinámico para la productividad total de los factores, tanto del sector industrial como del terciario en cada región, así como de la propensión del ahorro, la asignación regional de recursos, la propensión al consumo de los hogares y los efectos de la población.

  4. Task-specific modulation of effective connectivity during two simple unimanual motor tasks: A 122-channel EEG study

    DEFF Research Database (Denmark)

    Herz, Damian M.; Christensen, Mark S.; Reck, Christiane

    2012-01-01

    -related modulations of inter-regional coupling within a core motor network comprising the left primary motor cortex (M1), lateral premotor cortex (lPM) and supplementary motor area (SMA) were then modeled using dynamic causal modeling (DCM). A network model postulating coupling both within and across frequencies best...... captured observed spectral responses according to Bayesian model selection. DCM revealed dominant coupling within the β-band (13–30 Hz) between M1 and SMA during isometric contraction of the forearm, whereas fast repetitive finger movements were characterized by strong coupling within the γ-band (31–48 Hz......) and between the θ- (4–7 Hz) and the γ-band. This coupling pattern was mainly expressed in connections from lPM to SMA and from lPM to M1. We infer that human manual motor control involves task-specific modulation of inter-regional oscillatory coupling both within and across distinct frequency bands...

  5. Recurrent connections form a phase-locking neuronal tuner for frequency-dependent selective communication.

    Science.gov (United States)

    Shin, Dongkwan; Cho, Kwang-Hyun

    2013-01-01

    The brain requires task-dependent interregional coherence of information flow in the anatomically connected neural network. However, it is still unclear how a neuronal group can flexibly select its communication target. In this study, we revealed a hidden routing mechanism on the basis of recurrent connections. Our simulation results based on the spike response model show that recurrent connections between excitatory and inhibitory neurons modulate the resonant frequency of a local neuronal group, and that this modulation enables a neuronal group to receive selective information by filtering a preferred frequency component. We also found that the recurrent connection facilitates the successful routing of any necessary information flow between neuronal groups through frequency-dependent resonance of synchronized oscillations. Taken together, these results suggest that recurrent connections act as a phase-locking neuronal tuner which determines the resonant frequency of a local group and thereby controls the preferential routing of incoming signals.

  6. What Is Lost During Dreamless Sleep: The Relationship Between Neural Connectivity Patterns and Consciousness

    Directory of Open Access Journals (Sweden)

    Michaela Klimova

    2014-09-01

    Full Text Available Non-rapid eye movement (NREM sleep is characterised by reduced consciousness; thus, studying its neural characteristics acts as a useful indication of what is needed for conscious experience. The integrated information theory (Tononi, 2008 states that the ability of different thalamocortical regions to interact is crucial for consciousness, thereby motivating research concerning connectivity changes in the thalamocortical system that accompany changing consciousness levels. This review aims to discuss investigations of functional connectivity of resting-state and large-scale brain networks, applying correlational approaches to neuroimaging data as well as studies that used brain stimulation to investigate effective connectivity. Most findings suggest a reorganisation of functional brain networks where inter-region connectivity is reduced and intra-region connectivity is stronger in deep sleep than wakefulness.

  7. Impactos do crescimento do consumo de cafés especiais na competitividade inter-regional da atividade cafeeira

    Directory of Open Access Journals (Sweden)

    Mônica de Moura Pires

    2003-01-01

    Full Text Available Este trabalho tem como objetivo avaliar os impactos da expansão do consumo de cafés especiais no crescimento da competitividade inter-regional da atividade cafeeira e na distribuição funcional da renda. Os fluxos de bens e serviços contidos na Matriz de Contabilidade Social - MCS constituíram a base de dados para a construção do modelo aplicado de equilíbrio geral - MCEG. Um aumento de 1% no consumo mundial de café foi distribuído de forma diferenciada por região produtora: 30% para o Oeste Baiano, 25% para o Cerrado Mineiro, 25% para o Sul de Minas e 20% para a Zona da Mata Mineira. Os resultados indicam que a expansão da demanda internacional revela efeito positivo sobre as regiões produtoras com maior potencial de crescimento para a oferta de cafés especiais. O choque na demanda de café não foi acompanhado por choques de demanda em outros setores, o que provocou elevação nos preços dos fatores e, conseqüentemente, diminuição nos níveis do emprego dos fatores produtivos. A reestruturação espacial da atividade produtiva, para atender à demanda de nichos de mercados, apresenta-se, assim, potencialmente promissora para o produtor como forma de manutenção da competitividade do café brasileiro no mercado internacional.

  8. Interregional cytogenetic comparisons in Halichoeres and Thalassoma wrasses (Labridae) of coastal and insular regions of the southwestern Atlantic.

    Science.gov (United States)

    Amorim, K D J; Cioffi, M B; Bertollo, L A C; Soares, R X; Calado, L L; Borges, A T; Costa, G W W F; Molina, W F

    2017-05-10

    The distribution patterns of marine biodiversity are complex, resulting from vicariant events and species dispersion, as well as local ecological and adaptive conditions. Furthermore, the wide geographic distribution of some species may be hindered by biogeographical barriers that can interfere in the gene flow. Cytogenetic analyses in marine fishes, especially those involving populations in small remote insular environments, remain scarce. In the Western Atlantic, species of wrasses from the genera Halichoeres and Thalassoma occur in biogeographic arrangements that make it possible to analyze cytogenetic patterns between coastal and widely separated island populations. Species of these genera were punctually analyzed in some Atlantic regions. In this study, we compared several chromosomal features, such as karyotype macrostructure, heterochromatic patterns, patterns of base-specific fluorochromes, Ag-NORs, and 18S and 5S ribosomal sites in Thalassoma noronhanum, Halichoeres poeyi, and Halichoeres radiatus individuals from distinct coastal or insular regions of Atlantic. Notably, all of them are characterized by multiple 18S and 5S rDNA sites with syntenic arrangements in some chromosome pairs. Individuals of T. noronhanum (between the insular regions of Rocas Atoll and Fernando de Noronha Archipelago - FNA) and H. poeyi (coastal areas from Northeastern Brazil) show no detectable differences among their cytogenetic patterns. On the other hand, H. radiatus from FNA and São Pedro and São Paulo Archipelago exhibit differences in the frequency of rDNA sites that could suggest some level of population structuring between these insular regions. Interregional cytogenetic inventories of marine species with wide geographic distribution need to be rapidly expanded. These data will allow a better understanding of the level of chromosomal stability between vast oceanic spaces, which may be less than previously thought.

  9. Altered fMRI connectivity dynamics in temporal lobe epilepsy might explain seizure semiology

    Directory of Open Access Journals (Sweden)

    Helmut eLaufs

    2014-09-01

    Full Text Available Abstract: Temporal lobe epilepsy (TLE can be conceptualized as a network disease. The network can be characterized by inter-regional functional connectivity, i.e. blood oxygen level-dependent (BOLD signal correlations between any two region pairs. However, functional connectivity is not constant over time, thus computing correlation at a given time and then at some later time could give different results (non-stationarity. We hypothesized (1 that non-stationarities can be induced by epilepsy (e.g. interictal epileptic activity increasing local signal variance and that (2 these transient events contribute to fluctuations in connectivity leading to pathological functioning, i.e. TLE semiology. We analyzed fMRI data from 27 patients with TLE and 22 healthy controls focusing on EEG-confirmed wake epochs only to protect against sleep-induced connectivity changes. Testing hypothesis (1, we identified brain regions where the BOLD signal variance was significantly greater in TLE than in controls: the temporal pole - including the hippocampus. Taking the latter as the seed region and testing hypothesis (2 we calculated the time-varying interregional correlation values (dynamic functional connectivity to other brain regions and found greater connectivity variance in the TLE than the control group mainly in the precuneus, the supplementary and sensori-motor and the frontal cortices.We conclude that the highest BOLD signal variance in the hippocampi is highly suggestive of a specific epilepsy-related effect. The altered connectivity dynamics in TLE patients might help to explain the hallmark semiological features of dyscognitive seizures including impaired consciousness (precuneus, frontal cortex, sensory disturbance and motor automatisms (sensorimotor cortices, supplementary motor cortex. Accounting for the non-stationarity and state-dependence of functional connectivity are a prerequisite in the search for potential connectivity-derived biomarkers in TLE.

  10. Altered FMRI connectivity dynamics in temporal lobe epilepsy might explain seizure semiology.

    Science.gov (United States)

    Laufs, Helmut; Rodionov, Roman; Thornton, Rachel; Duncan, John Sydney; Lemieux, Louis; Tagliazucchi, Enzo

    2014-01-01

    Temporal lobe epilepsy (TLE) can be conceptualized as a network disease. The network can be characterized by inter-regional functional connectivity, i.e., blood oxygen level-dependent (BOLD) signal correlations between any two regions. However, functional connectivity is not constant over time, thus computing correlation at a given time and then at some later time could give different results (non-stationarity). We hypothesized (1) that non-stationarities can be induced by epilepsy (e.g., interictal epileptic activity) increasing local signal variance and that (2) these transient events contribute to fluctuations in connectivity leading to pathological functioning, i.e., TLE semiology. We analyzed fMRI data from 27 patients with TLE and 22 healthy controls focusing on EEG-confirmed wake epochs only to protect against sleep-induced connectivity changes. Testing hypothesis (1), we identified brain regions where the BOLD signal variance was significantly greater in TLE than in controls: the temporal pole - including the hippocampus. Taking the latter as the seed region and testing hypothesis (2), we calculated the time-varying inter-regional correlation values (dynamic functional connectivity) to other brain regions and found greater connectivity variance in the TLE than the control group mainly in the precuneus, the supplementary and sensorimotor, and the frontal cortices. We conclude that the highest BOLD signal variance in the hippocampi is highly suggestive of a specific epilepsy-related effect. The altered connectivity dynamics in TLE patients might help to explain the hallmark semiological features of dyscognitive seizures including impaired consciousness (precuneus, frontal cortex), sensory disturbance, and motor automatisms (sensorimotor cortices, supplementary motor cortex). Accounting for the non-stationarity and state-dependence of functional connectivity are a prerequisite in the search for potential connectivity-derived biomarkers in TLE.

  11. The effect of social networks and norms on the inter-regional migration intentions of knowledge-workers: The case of Saxony, Germany

    DEFF Research Database (Denmark)

    Kaplan, Sigal; Gruenwald, Luise; Hirte, Georg

    2016-01-01

    This study investigates the migration intentions of current and future knowledge-workers in Saxony, Germany. A structural equation model (SEM) is applied to analyze the impact of social networks and norms on inter-regional migration, in addition to lifestyle and utilitarian location factors...... relate to having origins, close friends and family in Saxony, and positive consideration of Saxony as an option by the parent; (iii) the structure of the social networks and norms is related to socio-economic characteristics, travel habits, and on-line social networks. (C) 2016 Elsevier Ltd. All rights...

  12. Metabolic connectivity analysis in Alzheimer’s disease (AD) by interregional correlation combining [11C] PIB and [18F] FDG PET

    NARCIS (Netherlands)

    Reesink, Fransje

    2015-01-01

    Objectives: to determine whether [18F] FDG PET brain pattern correlates with [11C] PIB uptake in AD specific brain region using a SPM (Statistical Parametric Mapping) based network analysis. Methods: Combined [11C] PIB and [18F] FDG PET patterns data of 15 patients: 3 controls (CP), 8 probable

  13. Gendered Connections

    DEFF Research Database (Denmark)

    Jensen, Steffen Bo

    2009-01-01

    This article explores the gendered nature of urban politics in Cape Town by focusing on a group of female, township politicians. Employing the Deleuzian concept of `wild connectivity', it argues that these politically entrepreneurial women were able to negotiate a highly volatile urban landscape ...... of connectivity might endure, as Capetonian politics assumes a post-apartheid structure....

  14. About connections.

    Science.gov (United States)

    Rockland, Kathleen S

    2015-01-01

    Despite the attention attracted by "connectomics", one can lose sight of the very real questions concerning "What are connections?" In the neuroimaging community, "structural" connectivity is ground truth and underlying constraint on "functional" or "effective" connectivity. It is referenced to underlying anatomy; but, as increasingly remarked, there is a large gap between the wealth of human brain mapping and the relatively scant data on actual anatomical connectivity. Moreover, connections have typically been discussed as "pairwise", point x projecting to point y (or: to points y and z), or more recently, in graph theoretical terms, as "nodes" or regions and the interconnecting "edges". This is a convenient shorthand, but tends not to capture the richness and nuance of basic anatomical properties as identified in the classic tradition of tracer studies. The present short review accordingly revisits connectional weights, heterogeneity, reciprocity, topography, and hierarchical organization, drawing on concrete examples. The emphasis is on presynaptic long-distance connections, motivated by the intention to probe current assumptions and promote discussions about further progress and synthesis.

  15. About Connections

    Directory of Open Access Journals (Sweden)

    Kathleen S Rockland

    2015-05-01

    Full Text Available Despite the attention attracted by connectomics, one can lose sight of the very real questions concerning What are connections? In the neuroimaging community, structural connectivity is ground truth and underlying constraint on functional or effective connectivity. It is referenced to underlying anatomy; but, as increasingly remarked, there is a large gap between the wealth of human brain mapping and the relatively scant data on actual anatomical connectivity. Moreover, connections have typically been discussed as pairwise, point x projecting to point y (or: to points y and z, or more recently, in graph theoretical terms, as nodes or regions and the interconnecting edges. This is a convenient shorthand, but tends not to capture the richness and nuance of basic anatomical properties as identified in the classic tradition of tracer studies. The present short review accordingly revisits connectional weights, heterogeneity, reciprocity, topography, and hierarchical organization, drawing on concrete examples. The emphasis is on presynaptic long-distance connections, motivated by the intention to probe current assumptions and promote discussions about further progress and synthesis.

  16. MODEL KERJASAMA ANTAR DAERAH DALAM PERENCANAAN SISTEM TRANSPORTASI WILAYAH METROPOLITAN BANDUNG RAYA (Inter-regional Cooperation Model of Transportation System Planning in the Greater Bandung Metropolitan

    Directory of Open Access Journals (Sweden)

    Tessa Talitha

    2014-11-01

    Full Text Available Decentralization policy in Indonesia gives development authority at local government level which cause fragmentation among regions. On the other hand, there are some government affairs that need to be managed jointly between several regions, so that inter-regional cooperation is necessary. Greater Bandung Metropolitan has rapid development from Bandung City to regions arround it. With the increasing of activity rate, good infrastructure planning including transportation system planning are needed. Decision making in planning implies many considerations, so that transaction cost such as information, negotiation, enforcement, and agency were involved. For the purpose of increasing public services, study of inter-regional collaboration models are needed. Based on the analysis, found that there are factors that will cause transaction costs such as unequal distribution of information, conflict of interest, actor who dominates, and lack of commitments of stakeholders. Then the results obtained that the model that appropriate to applied in Greater Bandung Metropolitan is jointly-formed authority, which is an institution consisting of representatives from each local governments and has the authority to execute policy in particular sector.

  17. Evaluating the economic damages of transport disruptions using a transnational and interregional input-output model for Japan, China, and South Korea

    Science.gov (United States)

    Irimoto, Hiroshi; Shibusawa, Hiroyuki; Miyata, Yuzuru

    2017-10-01

    Damage to transportation networks as a result of natural disasters can lead to economic losses due to lost trade along those links in addition to the costs of damage to the infrastructure itself. This study evaluates the economic damages of transport disruptions such as highways, tunnels, bridges, and ports using a transnational and interregional Input-Output Model that divides the world into 23 regions: 9 regions in Japan, 7 regions in China, and 4 regions in Korea, Taiwan, ASEAN5, and the USA to allow us to focus on Japan's regional and international links. In our simulation, economic ripple effects of both international and interregional transport disruptions are measured by changes in the trade coefficients in the input-output model. The simulation showed that, in the case of regional links in Japan, a transport disruption in the Kanmon Straits causes the most damage to our targeted world, resulting in economic damage of approximately 36.3 billion. In the case of international links among Japan, China, and Korea, damage to the link between Kanto in Japan and Huabei in China causes economic losses of approximately 31.1 billion. Our result highlights the importance of disaster prevention in the Kanmon Straits, Kanto, and Huabei to help ensure economic resilience.

  18. HR Connect

    Data.gov (United States)

    US Agency for International Development — HR Connect is the USAID HR personnel system which allows HR professionals to process HR actions related to employee's personal and position information. This system...

  19. Mathematics Connection

    African Journals Online (AJOL)

    MATHEMATICS CONNECTION aims at providing a forum topromote the development of Mathematics Education in Ghana. Articles that seekto enhance the teaching and/or learning of mathematics at all levels of theeducational system are welcome.

  20. The pro-fusion domain of herpes simplex virus glycoprotein D (gD) interacts with the gD N terminus and is displaced by soluble forms of viral receptors.

    Science.gov (United States)

    Fusco, Daniela; Forghieri, Cristina; Campadelli-Fiume, Gabriella

    2005-06-28

    Entry of herpes simplex virus into the cell requires the interaction of gD with one of its receptors, herpesvirus entry mediator or nectin 1, and the intervention of gB, gH, or gL, required to execute fusion of the virion envelope with cell membranes. The gD ectodomain is organized in two structurally and functionally differentiated regions. The N terminus (residues 1-260) carries the receptor binding sites, and the C terminus (residues 260-310) functions as the pro-fusion domain (PFD), which is required for viral infectivity and fusion but not for receptor binding. The objective of our studies is to elucidate how gD links receptor recognition to the triggering of fusion. Here, we show that PFD is made of subdomains 1 and 2 (amino acids 260-285 and 285-310). Each one partially contributed to herpes simplex virus infectivity. By means of glutathione S-transferase (GST) fusion proteins, we show that PFD bound soluble forms of gD, truncated at residue 260 (gD260t) or downstream. Both PFD subdomains bound gD260t, highlighting multiple contact sites between the N and C termini of gD. When gD260t was in complex with either receptor, it failed to bind GST-PFD. In turn, the receptors did not bind GST-PFD, irrespective of whether they were in complex with gD. Thus, gD260t interacted with the C terminus only if unbound to the receptor. We propose that (i) before receptor binding, gD adopts a "closed" conformation in which the N and C termini interact; and (ii) on encounter with a receptor, gD modifies its conformation and the N and C termini are released from reciprocal interactions ("opened" conformation) and enabled to trigger fusion.

  1. Correlated inter-regional variations in low frequency local field potentials and resting state BOLD signals within S1 cortex of monkeys.

    Science.gov (United States)

    Wilson, George H; Yang, Pai-Feng; Gore, John C; Chen, Li Min

    2016-08-01

    The hypothesis that specific frequency components of the spontaneous local field potentials (LFPs) underlie low frequency fluctuations of resting state fMRI (rsfMRI) signals was tested. The previous analyses of rsfMRI signals revealed differential inter-regional correlations among areas 3a, 3b, and 1 of primary somatosensory cortex (S1) in anesthetized monkeys (Wang et al. [2013]: Neuron 78:1116-1126). Here LFP band(s) which correlated between S1 regions, and how these inter-regional correlation differences covaried with rsfMRI signals were examined. LFP signals were filtered into seven bands (delta, theta, alpha, beta, gamma low, gamma high, and gamma very high), and then a Hilbert transformation was applied to obtain measures of instantaneous amplitudes and temporal lags between regions of interest (ROI) digit-digit pairs (areas 3b-area 1, area 3a-area 1, area 3a-area 3b) and digit-face pairs (area 3b-face, area 1-face, and area 3a-face). It was found that variations in the inter-regional correlation strengths between digit-digit and digit-face pairs in the delta (1-4 Hz), alpha (9-14 Hz), beta (15-30 Hz), and gamma (31-50 Hz) bands parallel those of rsfMRI signals to varying degrees. Temporal lags between digit-digit area pairs varied across LFP bands, with area 3a mostly leading areas 1/2 and 3b. In summary, the data demonstrates that the low and middle frequency range (1-50 Hz) of spontaneous LFP signals similarly covary with the low frequency fluctuations of rsfMRI signals within local circuits of S1, supporting a neuronal electrophysiological basis of rsfMRI signals. Inter-areal LFP temporal lag differences provided novel insights into the directionality of information flow among S1 areas at rest. Hum Brain Mapp 37:2755-2766, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  2. Dynamic Correlations between Intrinsic Connectivity and Extrinsic Connectivity of the Auditory Cortex in Humans

    Directory of Open Access Journals (Sweden)

    Zhuang Cui

    2017-08-01

    Full Text Available The arrival of sound signals in the auditory cortex (AC triggers both local and inter-regional signal propagations over time up to hundreds of milliseconds and builds up both intrinsic functional connectivity (iFC and extrinsic functional connectivity (eFC of the AC. However, interactions between iFC and eFC are largely unknown. Using intracranial stereo-electroencephalographic recordings in people with drug-refractory epilepsy, this study mainly investigated the temporal dynamic of the relationships between iFC and eFC of the AC. The results showed that a Gaussian wideband-noise burst markedly elicited potentials in both the AC and numerous higher-order cortical regions outside the AC (non-auditory cortices. Granger causality analyses revealed that in the earlier time window, iFC of the AC was positively correlated with both eFC from the AC to the inferior temporal gyrus and that to the inferior parietal lobule. While in later periods, the iFC of the AC was positively correlated with eFC from the precentral gyrus to the AC and that from the insula to the AC. In conclusion, dual-directional interactions occur between iFC and eFC of the AC at different time windows following the sound stimulation and may form the foundation underlying various central auditory processes, including auditory sensory memory, object formation, integrations between sensory, perceptional, attentional, motor, emotional, and executive processes.

  3. Connected Traveler

    Energy Technology Data Exchange (ETDEWEB)

    2016-06-01

    The Connected Traveler framework seeks to boost the energy efficiency of personal travel and the overall transportation system by maximizing the accuracy of predicted traveler behavior in response to real-time feedback and incentives. It is anticipated that this approach will establish a feedback loop that 'learns' traveler preferences and customizes incentives to meet or exceed energy efficiency targets by empowering individual travelers with information needed to make energy-efficient choices and reducing the complexity required to validate transportation system energy savings. This handout provides an overview of NREL's Connected Traveler project, including graphics, milestones, and contact information.

  4. Making connections

    NARCIS (Netherlands)

    Marion Duimel

    2007-01-01

    Original title: Verbinding maken; senioren en internet. More and more older people are finding their way to the Internet. Many people aged over 50 who have only recently gone online say that a new world has opened up for them. By connecting to the Internet they have the feeling that they

  5. CMS Connect

    Science.gov (United States)

    Balcas, J.; Bockelman, B.; Gardner, R., Jr.; Hurtado Anampa, K.; Jayatilaka, B.; Aftab Khan, F.; Lannon, K.; Larson, K.; Letts, J.; Marra Da Silva, J.; Mascheroni, M.; Mason, D.; Perez-Calero Yzquierdo, A.; Tiradani, A.

    2017-10-01

    The CMS experiment collects and analyzes large amounts of data coming from high energy particle collisions produced by the Large Hadron Collider (LHC) at CERN. This involves a huge amount of real and simulated data processing that needs to be handled in batch-oriented platforms. The CMS Global Pool of computing resources provide +100K dedicated CPU cores and another 50K to 100K CPU cores from opportunistic resources for these kind of tasks and even though production and event processing analysis workflows are already managed by existing tools, there is still a lack of support to submit final stage condor-like analysis jobs familiar to Tier-3 or local Computing Facilities users into these distributed resources in an integrated (with other CMS services) and friendly way. CMS Connect is a set of computing tools and services designed to augment existing services in the CMS Physics community focusing on these kind of condor analysis jobs. It is based on the CI-Connect platform developed by the Open Science Grid and uses the CMS GlideInWMS infrastructure to transparently plug CMS global grid resources into a virtual pool accessed via a single submission machine. This paper describes the specific developments and deployment of CMS Connect beyond the CI-Connect platform in order to integrate the service with CMS specific needs, including specific Site submission, accounting of jobs and automated reporting to standard CMS monitoring resources in an effortless way to their users.

  6. Detecting Mild Traumatic Brain Injury Using Resting State Magnetoencephalographic Connectivity.

    Directory of Open Access Journals (Sweden)

    Vasily A Vakorin

    2016-12-01

    Full Text Available Accurate means to detect mild traumatic brain injury (mTBI using objective and quantitative measures remain elusive. Conventional imaging typically detects no abnormalities despite post-concussive symptoms. In the present study, we recorded resting state magnetoencephalograms (MEG from adults with mTBI and controls. Atlas-guided reconstruction of resting state activity was performed for 90 cortical and subcortical regions, and calculation of inter-regional oscillatory phase synchrony at various frequencies was performed. We demonstrate that mTBI is associated with reduced network connectivity in the delta and gamma frequency range (>30 Hz, together with increased connectivity in the slower alpha band (8-12 Hz. A similar temporal pattern was associated with correlations between network connectivity and the length of time between the injury and the MEG scan. Using such resting state MEG network synchrony we were able to detect mTBI with 88% accuracy. Classification confidence was also correlated with clinical symptom severity scores. These results provide the first evidence that imaging of MEG network connectivity, in combination with machine learning, has the potential to accurately detect and determine the severity of mTBI.

  7. Chattonella (Raphidophyceae) bloom spatio-temporal variations in Tachibana Bay and the southern area of Ariake Sea, Japan: Interregional displacement patterns with Skeletonema (Bacillariophyceae).

    Science.gov (United States)

    Aoki, Kazuhiro; Onitsuka, Goh; Shimizu, Manabu; Yamatogi, Toshifumi; Ishida, Naoya; Kitahara, Shigeru; Hirano, Keiji

    2015-10-15

    In 2010, a massive bloom of the raphidophycean flagellate Chattonella occurred in the Ariake Sea and Tachibana Bay. Bloom dynamics and hydrographical conditions were examined by field survey. The development and decline of the bloom occurred three times in Tachibana Bay. First and third bloom developments synchronized with precipitation, and the second bloom developed in synchronization with a salinity decrease which occurred in relation to an increase of river discharge from the Chikugo River which takes several days to flow from the Ariake Sea. These results imply that the bloom was transported with the low salinity water from the Ariake Sea to Tachibana Bay. During blooms along the northern coast of Shimabara Peninsula, the predominant phytoplankton species changed from Chattonella to Skeletonema. Low salinity water intrusion induced an interregional difference of the Chattonella and Skeletonema bloom spatially-differentiated by the salinity in the Ariake Sea and Tachibana Bay. Copyright © 2015 Elsevier Ltd. All rights reserved.

  8. A Friend in Need. A Friend in Deed? ASEAN-EU Interregionalism in the Light of Non-Traditional Security Crises in South-East Asia

    Directory of Open Access Journals (Sweden)

    Naila Maier-Knapp

    2010-01-01

    Full Text Available The aim of this article is to assess the European Union’s (EU engagement with and within the Association of Southeast Asian Nations (ASEAN member states in the field of non-traditional security (NTS between 1997 and 2009, prior to the Lisbon Treaty becoming effective. The analysis concentrates on the EU’s response to five NTS crises and the interregional level of interaction from a sector-specific governance and social-constructivist approach. These crises are the avian influenza, the political conflict and the tsunami in Aceh, the Bali bombings and the Asian financial crisis (AFC in South-East Asia. The case studies illustrate EU NTS action and gauge EU NTS actorness from a South-East Asian perspective to substantiate the EU’s interregional interaction and external actorness quality in specific fields of governance in a region so far away. ----- Dieser Artikel analysiert die Zusammenarbeit der Europäischen Union (EU mit den Mitglieds- staaten der Vereinigung südostasiatischer Nationen (ASEAN im Bereich nicht-traditioneller Sicherheit (NTS zwischen 1997 und 2009, also noch vor Inkrafttreten des Vertrages von Lissabon. Fünf NTS-Krisen (Vogelgrippe, politischer Konflikt und Tsunami in Aceh, Bombenanschläge auf Bali sowie Asien-Finanzkrise, die Reaktionen der EU auf diese, sowie die entsprechenden Interaktionen auf der interregionalen Kooperationsebene stehen im Mittelpunkt der Analyse, welche einen sozialkonstruktivistischen und sektorspezifischen Governance-Ansatz verfolgt. Die Fallstudien legen die NTS-Aktivitäten der EU dar und bieten eine Einschätzung ihrer Akteursqualität aus südostasiatischer Perspektive. Des Weiteren wird versucht, die Qualität der interregionalen europäisch-südostasiatischen Interaktionen und der EU-Akteursqualität in ausgewählten Governance-Bereichen in einer derart weit entfernten Region darzustellen.

  9. Differential changes of metabolic brain activity and interregional functional coupling in prefronto-limbic pathways during different stress conditions: Functional imaging in freely behaving rodent pups

    Directory of Open Access Journals (Sweden)

    Joerg eBock

    2012-05-01

    Full Text Available The trumpet-tailed rat or degu (Octodon degus is an established model to investigate the consequences of early stress on the development of emotional brain circuits and behaviour. The aim of this study was to identify brain circuits, that respond to different stress conditions and to test if acute stress alters functional coupling of brain activity among prefrontal and limbic regions. Using functional imaging (2-Fluoro-deoxyglucose method in 8 day old male degu pups the following stress conditions were compared: (A pups together with parents and siblings (control, (B separation of the litter from the parents, (C individual separation from parents and siblings, (D individual separation and presentation of maternal calls. Condition (B significantly downregulated brain activity in the prefrontal cortex, hippocampus, nucleus accumbens and sensory areas compared to controls. Activity decrease was even more pronounced during condition (C, where, in contrast to all other regions, activity in the PAG was increased. Interestingly, brain activity in stress-associated brain regions such as the amygdala and habenula was not affected. In condition (D maternal vocalizations reactivated brain activity in the cingulate and precentral medial cortex, nucleus accumbens and striatum and in sensory areas. In contrast, reduced activity was measured in the prelimbic and infralimbic cortex and in the hippocampus and amygdala. Correlation analysis revealed complex, region- and situation-specific changes of interregional functional coupling among prefrontal and limbic brain regions during stress exposure. We show here for the first time that early life stress results in a widespread reduction of brain activity in the infant brain and changes interregional functional coupling. Moreover, maternal vocalizations can partly buffer stress-induced decrease in brain activity in some regions and evoked very different functional coupling patterns compared to the three other

  10. 78 FR 55684 - ConnectED Workshop

    Science.gov (United States)

    2013-09-11

    ... National Telecommunications and Information Administration ConnectED Workshop AGENCY: National... in the United States to next- generation broadband. This Notice announces that the ConnectED Workshop... ConnectED Workshop will discuss the growing bandwidth needs of K-12 schools as more schools use mobile...

  11. Connecting dots

    DEFF Research Database (Denmark)

    Murakami, Kyoko; Jacobs, Rachel L.

    2017-01-01

    and Middleton, 1995). A reminiscence conversation is a dynamic talk-in-interaction, which can produce valuable learning experience for the participants involved. Reminiscence talk contains rich, personal, historic data that can reveal and inform family members of an unknown past. In this seminar/chapter, we......Reminiscence is a self-reflecting process on past events and experiences. Not only does it enable past experiences to be brought to light through talk, but it also creates an affective environment, which allows participants to explore and construct a representation of the self (Buchanan...... of connecting the dots of recalled moments of individual family members lives and is geared towards building a family’s shared future for posterity. Lastly, we consider a wider implication of family reminiscence in terms of human development. http://www.infoagepub.com/products/Memory-Practices-and-Learning...

  12. Altered functional connectivity of the language network in ASD: Role of classical language areas and cerebellum☆

    Science.gov (United States)

    Verly, Marjolein; Verhoeven, Judith; Zink, Inge; Mantini, Dante; Peeters, Ronald; Deprez, Sabine; Emsell, Louise; Boets, Bart; Noens, Ilse; Steyaert, Jean; Lagae, Lieven; De Cock, Paul; Rommel, Nathalie; Sunaert, Stefan

    2014-01-01

    The development of language, social interaction and communicative skills is remarkably different in the child with autism spectrum disorder (ASD). Atypical brain connectivity has frequently been reported in this patient population. However, the neural correlates underlying their disrupted language development and functioning are still poorly understood. Using resting state fMRI, we investigated the functional connectivity properties of the language network in a group of ASD patients with clear comorbid language impairment (ASD-LI; N = 19) and compared them to the language related connectivity properties of 23 age-matched typically developing children. A verb generation task was used to determine language components commonly active in both groups. Eight joint language components were identified and subsequently used as seeds in a resting state analysis. Interestingly, both the interregional and the seed-based whole brain connectivity analysis showed preserved connectivity between the classical intrahemispheric language centers, Wernicke's and Broca's areas. In contrast however, a marked loss of functional connectivity was found between the right cerebellar region and the supratentorial regulatory language areas. Also, the connectivity between the interhemispheric Broca regions and modulatory control dorsolateral prefrontal region was found to be decreased. This disruption of normal modulatory control and automation function by the cerebellum may underlie the abnormal language function in children with ASD-LI. PMID:24567909

  13. Altered functional connectivity of the language network in ASD: Role of classical language areas and cerebellum

    Directory of Open Access Journals (Sweden)

    Marjolein Verly

    2014-01-01

    Full Text Available The development of language, social interaction and communicative skills is remarkably different in the child with autism spectrum disorder (ASD. Atypical brain connectivity has frequently been reported in this patient population. However, the neural correlates underlying their disrupted language development and functioning are still poorly understood. Using resting state fMRI, we investigated the functional connectivity properties of the language network in a group of ASD patients with clear comorbid language impairment (ASD-LI; N = 19 and compared them to the language related connectivity properties of 23 age-matched typically developing children. A verb generation task was used to determine language components commonly active in both groups. Eight joint language components were identified and subsequently used as seeds in a resting state analysis. Interestingly, both the interregional and the seed-based whole brain connectivity analysis showed preserved connectivity between the classical intrahemispheric language centers, Wernicke's and Broca's areas. In contrast however, a marked loss of functional connectivity was found between the right cerebellar region and the supratentorial regulatory language areas. Also, the connectivity between the interhemispheric Broca regions and modulatory control dorsolateral prefrontal region was found to be decreased. This disruption of normal modulatory control and automation function by the cerebellum may underlie the abnormal language function in children with ASD-LI.

  14. Default mode network connectivity as a function of familial and environmental risk for psychotic disorder.

    Directory of Open Access Journals (Sweden)

    Sanne C T Peeters

    Full Text Available Research suggests that altered interregional connectivity in specific networks, such as the default mode network (DMN, is associated with cognitive and psychotic symptoms in schizophrenia. In addition, frontal and limbic connectivity alterations have been associated with trauma, drug use and urban upbringing, though these environmental exposures have never been examined in relation to DMN functional connectivity in psychotic disorder.Resting-state functional MRI scans were obtained from 73 patients with psychotic disorder, 83 non-psychotic siblings of patients with psychotic disorder and 72 healthy controls. Posterior cingulate cortex (PCC seed-based correlation analysis was used to estimate functional connectivity within the DMN. DMN functional connectivity was examined in relation to group (familial risk, group × environmental exposure (to cannabis, developmental trauma and urbanicity and symptomatology.There was a significant association between group and PCC connectivity with the inferior parietal lobule (IPL, the precuneus (PCu and the medial prefrontal cortex (MPFC. Compared to controls, patients and siblings had increased PCC connectivity with the IPL, PCu and MPFC. In the IPL and PCu, the functional connectivity of siblings was intermediate to that of controls and patients. No significant associations were found between DMN connectivity and (subclinical psychotic/cognitive symptoms. In addition, there were no significant interactions between group and environmental exposures in the model of PCC functional connectivity.Increased functional connectivity in individuals with (increased risk for psychotic disorder may reflect trait-related network alterations. The within-network "connectivity at rest" intermediate phenotype was not associated with (subclinical psychotic or cognitive symptoms. The association between familial risk and DMN connectivity was not conditional on environmental exposure.

  15. The Assessment of the Dynamics of Region’s Participation in Interregional and International Exchange Processes Based on the Change in the Ratio of Intermediate and Final Products

    Directory of Open Access Journals (Sweden)

    Kasim Nazifovich Yusupov

    2017-06-01

    Full Text Available The article presents the hypothesis that the increase in the intermediate consumption caused by the growth of material costs due to innovation and modernization temporarily reduces the level of economic efficiency. This leads to further multiple increases of final product volume, which, in turn, increases the region’s economic potential and competitiveness, provides its enhanced participation in inter-regional and international exchange processes. The authors consider the main factors and conditions that determine the variation of these parameters in the market economy and discuss the intermediate and final product, export, import and others. The results of the analysis, calculations and statistics reveal and confirm the possibility of their measurement with the use of interindustry balances. The study aims at assessing the quantitative interdependence of intermediate and final products growth based on the analysis of interregional and international exchange in the system coordination to macroeconomic indicators of the socio-economic development of the region during the periods of planned and market economy. Another purpose is to determine the directions of the region’s participation in the division of labour and implementation of innovations in order to increase of gross domestic product. On the example of the development of Bashkortostan economy, the authors have revealed that a greater involvement of the region in the foreign economic processes led to the increase in the flow of exports and imports and the simultaneous reduction of production export to other regions of the Russian Federation and import from them. At the same time, the region has focused mainly on the export of fuel and energy products. The proportions of intermediate and final products in the period under review have changed by increasing the final products. That confirms the improvement of conditions for the growth of the region’s competitiveness. On the example of oil

  16. Network-based analysis reveals functional connectivity related to internet addiction tendency

    Directory of Open Access Journals (Sweden)

    Tanya eWen

    2016-02-01

    Full Text Available IntroductionPreoccupation and compulsive use of the internet can have negative psychological effects, such that it is increasingly being recognized as a mental disorder. The present study employed network-based statistics to explore how whole-brain functional connections at rest is related to the extent of individual’s level of internet addiction, indexed by a self-rated questionnaire. We identified two topologically significant networks, one with connections that are positively correlated with internet addiction tendency, and one with connections negatively correlated with internet addiction tendency. The two networks are interconnected mostly at frontal regions, which might reflect alterations in the frontal region for different aspects of cognitive control (i.e., for control of internet usage and gaming skills. Next, we categorized the brain into several large regional subgroupings, and found that the majority of proportions of connections in the two networks correspond to the cerebellar model of addiction which encompasses the four-circuit model. Lastly, we observed that the brain regions with the most inter-regional connections associated with internet addiction tendency replicate those often seen in addiction literature, and is corroborated by our meta-analysis of internet addiction studies. This research provides a better understanding of large-scale networks involved in internet addiction tendency and shows that pre-clinical levels of internet addiction are associated with similar regions and connections as clinical cases of addiction.

  17. Connectivity of communication networks

    CERN Document Server

    Mao, Guoqiang

    2017-01-01

    This book introduces a number of recent developments on connectivity of communication networks, ranging from connectivity of large static networks and connectivity of highly dynamic networks to connectivity of small to medium sized networks. This book also introduces some applications of connectivity studies in network optimization, in network localization, and in estimating distances between nodes. The book starts with an overview of the fundamental concepts, models, tools, and methodologies used for connectivity studies. The rest of the chapters are divided into four parts: connectivity of large static networks, connectivity of highly dynamic networks, connectivity of small to medium sized networks, and applications of connectivity studies.

  18. Impactos econômicos da introdução do milho Bt11 no Brasil: uma abordagem de equilíbrio geral inter-regional

    Directory of Open Access Journals (Sweden)

    Andressa Rodrigues Pavão

    2011-03-01

    Full Text Available Este trabalho analisa os impactos econômicos da adoção do milho Bt11 no Brasil, bem como as consequências da proibição deste cultivo apenas no Paraná, caso a lei estadual nº 14.162/03 entrasse em vigor. Para tal, utiliza-se um modelo computável de equilíbrio geral inter-regional, calibrado para 2001, simulando a redução de inseticida, mão de obra, combustível e lubrificantes, bem como o aumento de produtividade observado em lavouras de milho Bt11. Ao analisar a adoção nas regiões brasileiras "tecnificadas", observa-se o deslocamento de estoque de capital e mão de obra de todas as regiões para o Sul do País. Considerando-se que apenas o Paraná não adota milho Bt11, observa-se que tanto a mão de obra quanto o estoque de capital se deslocam do Sul e Sudeste para o Centro-Oeste do Brasil. Os resultados mais expressivos ocorrem no próprio estado do Paraná, onde não apenas o setor de milho, como também os setores a jusante perdem competitividade, reduzindo o nível de atividade, emprego e consumo das famílias. De forma geral, os efeitos da adoção do milho Bt11 são transmitidos ao longo da sua cadeia produtiva, gerando aumento do PIB, das exportações e do consumo das famílias, sendo mais expressivos nos setores e regiões diretamente relacionados com a cadeia de comercialização do milho, tais como os de criação animal e carnes, localizados, em sua maioria, no Sul do País.This study aims to analyze the economic impacts of the adoption of Bt11 corn in Brazil, as well as the consequences of the prohibition of the cultivation only in the Paraná state, if the state law number 14.162/03 would start to be active. For this purpose, an inter-regional general equilibrium computable model is used, gauged for 2001, simulating the reduction of insecticide, labor force, fuel and lubricants, as well as the increase in the yield observed in crops which use Bt11 corn. When the adoption of Bt11 corn in "technified" Brazilian

  19. Africa's intra-regional, inter-regional and intercontinental electricity trade - Techno-politico-economic considerations and future prospects

    Energy Technology Data Exchange (ETDEWEB)

    Ram, Babu

    2007-07-01

    The majority of Africa's population does not have access to electricity. The Sub-Saharan African is largely hit save South Africa. Among the many reasons for this situation, the major one is: the insufficient growth of the investment against the demand of electricity. This is to say that the investment has not been able to keep pace with the demand which has been rising with the growing population and with the economic activities. As a result, there is a backlog of investment. To circumvent this situation, 4 billion dollar annual investment is needed in the electricity sector. But the risks and high transaction costs of African economies deter investors and are relatively unable to attract them. Furthermore, a number of African economies are small due to which the benefits of the economy of scale are not realizable. Moreover, isolated and individualistic planning makes countries incur huge investment and makes the supply of electricity to disadvantaged areas even costlier. The supply costs can be reduced by invoking meticulously to coordinated combined planning and regional integration. New Partnership for Africa's Development (NEPAD) advocates a development paradigm based on the principles of interdependence, cooperation, and regional integration. However, the absence of infrastructure and institutions and harmonized policies obstruct the integration of electricity supply systems. Creating regional electricity markets is a way to reduce risks and transaction costs and to lure investors to develop much needed electricity generation and transmission facilities for increasing electricity access in rural areas. This paper extends the themes of regional integration to establishing the regional electricity markets/power pools. It considers the intra-regional and inter-regional electricity trade in Africa. It also considers Africa's inter-continental trade that is its trade with Europe and Asia. This paper examines technical constraints, proposes solutions

  20. Identification of neural connectivity signatures of autism using machine learning.

    Science.gov (United States)

    Deshpande, Gopikrishna; Libero, Lauren E; Sreenivasan, Karthik R; Deshpande, Hrishikesh D; Kana, Rajesh K

    2013-01-01

    Alterations in interregional neural connectivity have been suggested as a signature of the pathobiology of autism. There have been many reports of functional and anatomical connectivity being altered while individuals with autism are engaged in complex cognitive and social tasks. Although disrupted instantaneous correlation between cortical regions observed from functional MRI is considered to be an explanatory model for autism, the causal influence of a brain area on another (effective connectivity) is a vital link missing in these studies. The current study focuses on addressing this in an fMRI study of Theory-of-Mind (ToM) in 15 high-functioning adolescents and adults with autism and 15 typically developing control participants. Participants viewed a series of comic strip vignettes in the MRI scanner and were asked to choose the most logical end to the story from three alternatives, separately for trials involving physical and intentional causality. The mean time series, extracted from 18 activated regions of interest, were processed using a multivariate autoregressive model (MVAR) to obtain the causality matrices for each of the 30 participants. These causal connectivity weights, along with assessment scores, functional connectivity values, and fractional anisotropy obtained from DTI data for each participant, were submitted to a recursive cluster elimination based support vector machine classifier to determine the accuracy with which the classifier can predict a novel participant's group membership (autism or control). We found a maximum classification accuracy of 95.9% with 19 features which had the highest discriminative ability between the groups. All of the 19 features were effective connectivity paths, indicating that causal information may be critical in discriminating between autism and control groups. These effective connectivity paths were also found to be significantly greater in controls as compared to ASD participants and consisted predominantly of

  1. Aberrant Functional Connectivity Architecture in Alzheimer's Disease and Mild Cognitive Impairment: A Whole-Brain, Data-Driven Analysis.

    Science.gov (United States)

    Zhou, Bo; Yao, Hongxiang; Wang, Pan; Zhang, Zengqiang; Zhan, Yafeng; Ma, Jianhua; Xu, Kaibin; Wang, Luning; An, Ningyu; Liu, Yong; Zhang, Xi

    2015-01-01

    The purpose of our study was to investigate whether the whole-brain functional connectivity pattern exhibits disease severity-related alterations in patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI). Resting-state functional magnetic resonance imaging data were acquired in 27 MCI subjects, 35 AD patients, and 27 age- and gender-matched subjects with normal cognition (NC). Interregional functional connectivity was assessed based on a predefined template which parcellated the brain into 90 regions. Altered whole-brain functional connectivity patterns were identified via connectivity comparisons between the AD and NC subjects. Finally, the relationship between functional connectivity strength and cognitive ability according to the mini-mental state examination (MMSE) was evaluated in the MCI and AD groups. Compared with the NC group, the AD group exhibited decreased functional connectivities throughout the brain. The most significantly affected regions included several important nodes of the default mode network and the temporal lobe. Moreover, changes in functional connectivity strength exhibited significant associations with disease severity-related alterations in the AD and MCI groups. The present study provides novel evidence and will facilitate meta-analysis of whole-brain analyses in AD and MCI, which will be critical to better understand the neural basis of AD.

  2. Intermodal Passenger Connectivity Database -

    Data.gov (United States)

    Department of Transportation — The Intermodal Passenger Connectivity Database (IPCD) is a nationwide data table of passenger transportation terminals, with data on the availability of connections...

  3. Minimum cost connection networks

    DEFF Research Database (Denmark)

    Hougaard, Jens Leth; Tvede, Mich

    In the present paper we consider the allocation of cost in connection networks. Agents have connection demands in form of pairs of locations they want to be connected. Connections between locations are costly to build. The problem is to allocate costs of networks satisfying all connection demands....... We use three axioms to characterize allocation rules that truthfully implement cost minimizing networks satisfying all connection demands in a game where: (1) a central planner announces an allocation rule and a cost estimation rule; (2) every agent reports her own connection demand as well as all...... connection costs; and, (3) the central planner selects a cost minimizing network satisfying reported connection demands based on estimated connection costs and allocates true connection costs of the selected network....

  4. Connecting the Brain to Itself through an Emulation

    Directory of Open Access Journals (Sweden)

    Mijail D. Serruya

    2017-06-01

    Full Text Available Pilot clinical trials of human patients implanted with devices that can chronically record and stimulate ensembles of hundreds to thousands of individual neurons offer the possibility of expanding the substrate of cognition. Parallel trains of firing rate activity can be delivered in real-time to an array of intermediate external modules that in turn can trigger parallel trains of stimulation back into the brain. These modules may be built in software, VLSI firmware, or biological tissue as in vitro culture preparations or in vivo ectopic construct organoids. Arrays of modules can be constructed as early stage whole brain emulators, following canonical intra- and inter-regional circuits. By using machine learning algorithms and classic tasks known to activate quasi-orthogonal functional connectivity patterns, bedside testing can rapidly identify ensemble tuning properties and in turn cycle through a sequence of external module architectures to explore which can causatively alter perception and behavior. Whole brain emulation both (1 serves to augment human neural function, compensating for disease and injury as an auxiliary parallel system, and (2 has its independent operation bootstrapped by a human-in-the-loop to identify optimal micro- and macro-architectures, update synaptic weights, and entrain behaviors. In this manner, closed-loop brain-computer interface pilot clinical trials can advance strong artificial intelligence development and forge new therapies to restore independence in children and adults with neurological conditions.

  5. Connecting the Brain to Itself through an Emulation.

    Science.gov (United States)

    Serruya, Mijail D

    2017-01-01

    Pilot clinical trials of human patients implanted with devices that can chronically record and stimulate ensembles of hundreds to thousands of individual neurons offer the possibility of expanding the substrate of cognition. Parallel trains of firing rate activity can be delivered in real-time to an array of intermediate external modules that in turn can trigger parallel trains of stimulation back into the brain. These modules may be built in software, VLSI firmware, or biological tissue as in vitro culture preparations or in vivo ectopic construct organoids. Arrays of modules can be constructed as early stage whole brain emulators, following canonical intra- and inter-regional circuits. By using machine learning algorithms and classic tasks known to activate quasi-orthogonal functional connectivity patterns, bedside testing can rapidly identify ensemble tuning properties and in turn cycle through a sequence of external module architectures to explore which can causatively alter perception and behavior. Whole brain emulation both (1) serves to augment human neural function, compensating for disease and injury as an auxiliary parallel system, and (2) has its independent operation bootstrapped by a human-in-the-loop to identify optimal micro- and macro-architectures, update synaptic weights, and entrain behaviors. In this manner, closed-loop brain-computer interface pilot clinical trials can advance strong artificial intelligence development and forge new therapies to restore independence in children and adults with neurological conditions.

  6. Atypically diffuse functional connectivity between caudate nuclei and cerebral cortex in autism

    Directory of Open Access Journals (Sweden)

    Turner Katherine C

    2006-10-01

    Full Text Available Abstract Background Autism is a neurodevelopmental disorder affecting sociocommunicative behavior, but also sensorimotor skill learning, oculomotor control, and executive functioning. Some of these impairments may be related to abnormalities of the caudate nuclei, which have been reported for autism. Methods Our sample was comprised of 8 high-functioning males with autism and 8 handedness, sex, and age-matched controls. Subjects underwent functional MRI scanning during performance on simple visuomotor coordination tasks. Functional connectivity MRI (fcMRI effects were identified as interregional blood oxygenation level dependent (BOLD signal cross-correlation, using the caudate nuclei as seed volumes. Results In the control group, fcMRI effects were found in circuits with known participation of the caudate nuclei (associative, orbitofrontal, oculomotor, motor circuits. Although in the autism group fcMRI effects within these circuits were less pronounced or absent, autistic subjects showed diffusely increased connectivity mostly in pericentral regions, but also in brain areas outside expected anatomical circuits (such as visual cortex. Conclusion These atypical connectivity patterns may be linked to developmental brain growth disturbances recently reported in autism and suggest inefficiently organized functional connectivity between caudate nuclei and cerebral cortex, potentially accounting for stereotypic behaviors and executive impairments.

  7. Diagnostic classification of intrinsic functional connectivity highlights somatosensory, default mode, and visual regions in autism

    Directory of Open Access Journals (Sweden)

    Colleen P. Chen

    2015-01-01

    Full Text Available Despite consensus on the neurological nature of autism spectrum disorders (ASD, brain biomarkers remain unknown and diagnosis continues to be based on behavioral criteria. Growing evidence suggests that brain abnormalities in ASD occur at the level of interconnected networks; however, previous attempts using functional connectivity data for diagnostic classification have reached only moderate accuracy. We selected 252 low-motion resting-state functional MRI (rs-fMRI scans from the Autism Brain Imaging Data Exchange (ABIDE including typically developing (TD and ASD participants (n = 126 each, matched for age, non-verbal IQ, and head motion. A matrix of functional connectivities between 220 functionally defined regions of interest was used for diagnostic classification, implementing several machine learning tools. While support vector machines in combination with particle swarm optimization and recursive feature elimination performed modestly (with accuracies for validation datasets <70%, diagnostic classification reached a high accuracy of 91% with random forest (RF, a nonparametric ensemble learning method. Among the 100 most informative features (connectivities, for which this peak accuracy was achieved, participation of somatosensory, default mode, visual, and subcortical regions stood out. Whereas some of these findings were expected, given previous findings of default mode abnormalities and atypical visual functioning in ASD, the prominent role of somatosensory regions was remarkable. The finding of peak accuracy for 100 interregional functional connectivities further suggests that brain biomarkers of ASD may be regionally complex and distributed, rather than localized.

  8. Modulation of steady state functional connectivity in the default mode and working memory networks by cognitive load.

    Science.gov (United States)

    Newton, Allen T; Morgan, Victoria L; Rogers, Baxter P; Gore, John C

    2011-10-01

    Interregional correlations between blood oxygen level dependent (BOLD) magnetic resonance imaging (fMRI) signals in the resting state have been interpreted as measures of connectivity across the brain. Here we investigate whether such connectivity in the working memory and default mode networks is modulated by changes in cognitive load. Functional connectivity was measured in a steady-state verbal identity N-back task for three different conditions (N = 1, 2, and 3) as well as in the resting state. We found that as cognitive load increases, the functional connectivity within both the working memory the default mode network increases. To test whether functional connectivity between the working memory and the default mode networks changed, we constructed maps of functional connectivity to the working memory network as a whole and found that increasingly negative correlations emerged in a dorsal region of the posterior cingulate cortex. These results provide further evidence that low frequency fluctuations in BOLD signals reflect variations in neural activity and suggests interaction between the default mode network and other cognitive networks. Copyright © 2010 Wiley-Liss, Inc.

  9. Minimum cost connection networks

    DEFF Research Database (Denmark)

    Hougaard, Jens Leth; Tvede, Mich

    2015-01-01

    In the present paper we consider the allocation of costs in connection networks. Agents have connection demands in form of pairs of locations they want to have connected. Connections between locations are costly to build. The problem is to allocate costs of networks satisfying all connection...... demands. We use a few axioms to characterize allocation rules that truthfully implement cost minimizing networks satisfying all connection demands in a game where: (1) a central planner announces an allocation rule and a cost estimation rule; (2) every agent reports her own connection demand as well...... as all connection costs; (3) the central planner selects a cost minimizing network satisfying reported connection demands based on the estimated costs; and, (4) the planner allocates the true costs of the selected network. It turns out that an allocation rule satisfies the axioms if and only if relative...

  10. Regional vulnerability of longitudinal cortical association connectivity

    Directory of Open Access Journals (Sweden)

    Rafael Ceschin

    2015-01-01

    correlated with alteration in eigenvector centrality, clustering coefficient (inter-regional and participation co-efficient (inter-modular alterations of frontal–striatal and fronto-limbic nodes suggesting re-organization of these pathways. Both along tract and structural topology network measurements correlated strongly with motor and visual clinical outcome scores. This study shows the value of combining along-tract analysis and structural network topology in depicting not only selective parietal occipital regional vulnerability but also reorganization of frontal–striatal and frontal–limbic pathways in preterm children with cerebral palsy. These finding also support the concept that widespread, but selective posterior–anterior neural network connectivity alterations in preterm children with cerebral palsy likely contribute to the pathogenesis of neurosensory and cognitive impairment in this group.

  11. Identifying abnormal connectivity in patients using Dynamic Causal Modelling of fMRI responses.

    Directory of Open Access Journals (Sweden)

    Mohamed L Seghier

    2010-08-01

    Full Text Available Functional imaging studies of brain damaged patients offer a unique opportunity to understand how sensori-motor and cognitive tasks can be carried out when parts of the neural system that support normal performance are no longer available. In addition to knowing which regions a patient activates, we also need to know how these regions interact with one another, and how these inter-regional interactions deviate from normal. Dynamic Causal Modelling (DCM offers the opportunity to assess task-dependent interactions within a set of regions. Here we review its use in patients when the question of interest concerns the characterisation of abnormal connectivity for a given pathology. We describe the currently available implementations of DCM for fMRI responses, varying from the deterministic bilinear models with one-state equation to the stochastic nonlinear models with two-state equations. We also highlight the importance of the new Bayesian model selection and averaging tools that allow different plausible models to be compared at the single subject and group level. These procedures allow inferences to be made at different levels of model selection, from features (model families to connectivity parameters. Following a critical review of previous DCM studies that investigated abnormal connectivity we propose a systematic procedure that will ensure more flexibility and efficiency when using DCM in patients. Finally, some practical and methodological issues crucial for interpreting or generalising DCM findings in patients are discussed.

  12. Review: Cortical construction in autism spectrum disorder: columns, connectivity and the subplate.

    Science.gov (United States)

    Hutsler, Jeffrey J; Casanova, Manuel F

    2016-02-01

    The cerebral cortex undergoes protracted maturation during human development and exemplifies how biology and environment are inextricably intertwined in the construction of complex neural circuits. Autism spectrum disorders are characterized by a number of pathological changes arising from this developmental process. These include: (i) alterations to columnar structure that have significant implications for the organization of cortical circuits and connectivity; (ii) alterations to synaptic spines on individual cortical units that may underlie specific types of connectional changes; and (iii) alterations within the cortical subplate, a region that plays a role in proper cortical development and in regulating interregional communication in the mature brain. Although the cerebral cortex is not the only structure affected in the disorder, it is a fundamental contributor to the behaviours that characterize autism. These alterations to cortical circuitry likely underlie the behavioural phenotype in autism and contribute to the unique pattern of deficits and strengths that characterize cognitive functioning. Recent findings within the cortical subplate may indicate that alterations to cortical construction begin prenatally, before activity-dependent connections are established, and are in need of further study. A better understanding of cortical development in autism spectrum disorders will draw bridges between the microanatomical computational circuitry and the atypical behaviours that arise when that circuitry is modified. In addition, it will allow us to better exploit the constructional plasticity within the brain to design more targeted interventions that better manage atypical cortical construction and that can be applied very early in postnatal life. © 2015 British Neuropathological Society.

  13. Altered effective connectivity of default model brain network underlying amnestic MCI

    Science.gov (United States)

    Yan, Hao; Wang, Yonghui; Tian, Jie

    2012-02-01

    Mild cognitive impairment (MCI) is the transitional, heterogeneous continuum from healthy elderly to Alzheimer's disease (AD). Previous studies have shown that brain functional activity in the default mode network (DMN) is impaired in MCI patients. However, the altered effective connectivity of the DMN in MCI patients remains largely unknown. The present study combined an independent component analysis (ICA) approach with Granger causality analysis (mGCA) to investigate the effective connectivity within the DMN in 12 amnestic MCI patients and 12 age-matched healthy elderly. Compared to the healthy control, the MCI exhibited decreased functional activity in the posterior DMN regions, as well as a trend towards activity increases in anterior DMN regions. Results from mGCA further supported this conclusion that the causal influence projecting to the precuneus/PCC became much weaker in MCI, while stronger interregional interactions emerged within the frontal-parietal cortices. These findings suggested that abnormal effective connectivity within the DMN may elucidate the dysfunctional and compensatory processes in MCI brain networks.

  14. Galois connections and applications

    CERN Document Server

    Erné, M; Wismath, S

    2004-01-01

    This book presents the main ideas of General Galois Theory as a generalization of Classical Galois Theory It sketches the development of Galois connections through the last three centuries Examples of Galois connections as powerful tools in Category Theory and Universal Algebra are given Applications of Galois connections in Linguistic and Data Analysis are presented

  15. Connecting to Everyday Practices

    DEFF Research Database (Denmark)

    Iversen, Ole Sejer; Smith, Rachel Charlotte

    2012-01-01

    construction and reproduction of cultural heritage creating novel connections between self and others and between past, present and future. We present experiences from a current research project, the Digital Natives exhibition, in which social media was designed as an integral part of the exhibition to connect...... focusing on the connections between audiences practices and the museum exhibition....

  16. Extracting multiscale pattern information of fMRI based functional brain connectivity with application on classification of autism spectrum disorders.

    Directory of Open Access Journals (Sweden)

    Hui Wang

    Full Text Available We employed a multi-scale clustering methodology known as "data cloud geometry" to extract functional connectivity patterns derived from functional magnetic resonance imaging (fMRI protocol. The method was applied to correlation matrices of 106 regions of interest (ROIs in 29 individuals with autism spectrum disorders (ASD, and 29 individuals with typical development (TD while they completed a cognitive control task. Connectivity clustering geometry was examined at both "fine" and "coarse" scales. At the coarse scale, the connectivity clustering geometry produced 10 valid clusters with a coherent relationship to neural anatomy. A supervised learning algorithm employed fine scale information about clustering motif configurations and prevalence, and coarse scale information about intra- and inter-regional connectivity; the algorithm correctly classified ASD and TD participants with sensitivity of 82.8% and specificity of 82.8%. Most of the predictive power of the logistic regression model resided at the level of the fine-scale clustering geometry, suggesting that cellular versus systems level disturbances are more prominent in individuals with ASD. This article provides validation for this multi-scale geometric approach to extracting brain functional connectivity pattern information and for its use in classification of ASD.

  17. Distinct functional connectivity of the hippocampus during semantic and phonemic fluency.

    Science.gov (United States)

    Glikmann-Johnston, Yifat; Oren, Noga; Hendler, Talma; Shapira-Lichter, Irit

    2015-03-01

    Verbal fluency tasks are typically used in neuropsychological practice for assessment of language function in a variety of neurological disorders. Recently, it has been shown that the hippocampus, a region thought to be exclusive to the domain of memory, is also involved in tests of semantic fluency. The present study further explores hippocampal contribution to verbal fluency using functional Magnetic Resonance Imaging (fMRI) and examining mean activity and inter-regional functional connectivity with known task-related brain regions. Given the clear lateralization of brain areas involved in language, lateralization of hippocampal involvement in semantic and phonemic word fluency was also investigated. Different hippocampal recruitment during semantic and phonemic fluency was found: greater change in activity was seen during semantic fluency, as compared with phonemic fluency. This pattern was obtained in the right and the left hippocampus, with no lateralization effects. Functional connectivity analyses corroborate the notion of selective contribution of the hippocampus to semantic fluency. During the semantic fluency task, connectivity levels between the hippocampi and components of the semantic network did not differ from connectivity levels within the semantic network. In contrast, during the phonemic fluency task, the hippocampi were less correlated with components of the phonemic network, as compared to the within phonemic network connectivity. Importantly, hippocampal connectivity with the semantic network was task-dependent and restricted to periods of semantic fluency performance. Altogether, results suggest that the right and the left hippocampus are integral components of the brain network that selectively supports verbal semantic fluency, but not phonemic fluency. Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. Aberrant Functional Connectivity Architecture in Alzheimer’s Disease and Mild Cognitive Impairment: A Whole-Brain, Data-Driven Analysis

    Directory of Open Access Journals (Sweden)

    Bo Zhou

    2015-01-01

    Full Text Available The purpose of our study was to investigate whether the whole-brain functional connectivity pattern exhibits disease severity-related alterations in patients with Alzheimer’s disease (AD and mild cognitive impairment (MCI. Resting-state functional magnetic resonance imaging data were acquired in 27 MCI subjects, 35 AD patients, and 27 age- and gender-matched subjects with normal cognition (NC. Interregional functional connectivity was assessed based on a predefined template which parcellated the brain into 90 regions. Altered whole-brain functional connectivity patterns were identified via connectivity comparisons between the AD and NC subjects. Finally, the relationship between functional connectivity strength and cognitive ability according to the mini-mental state examination (MMSE was evaluated in the MCI and AD groups. Compared with the NC group, the AD group exhibited decreased functional connectivities throughout the brain. The most significantly affected regions included several important nodes of the default mode network and the temporal lobe. Moreover, changes in functional connectivity strength exhibited significant associations with disease severity-related alterations in the AD and MCI groups. The present study provides novel evidence and will facilitate meta-analysis of whole-brain analyses in AD and MCI, which will be critical to better understand the neural basis of AD.

  19. Handbook of networking & connectivity

    CERN Document Server

    McClain, Gary R

    1994-01-01

    Handbook of Networking & Connectivity focuses on connectivity standards in use, including hardware and software options. The book serves as a guide for solving specific problems that arise in designing and maintaining organizational networks.The selection first tackles open systems interconnection, guide to digital communications, and implementing TCP/IP in an SNA environment. Discussions focus on elimination of the SNA backbone, routing SNA over internets, connectionless versus connection-oriented networks, internet concepts, application program interfaces, basic principles of layering, proto

  20. The Connected Traveler

    Energy Technology Data Exchange (ETDEWEB)

    Young, Stanley

    2017-04-24

    The Connected Traveler project is a multi-disciplinary undertaking that seeks to validate potential for transformative transportation system energy savings by incentivizing energy efficient travel behavior.

  1. Low-frequency connectivity is associated with mild traumatic brain injury

    Directory of Open Access Journals (Sweden)

    B.T. Dunkley

    2015-01-01

    Full Text Available Mild traumatic brain injury (mTBI occurs from a closed-head impact. Often referred to as concussion, about 20% of cases complain of secondary psychological sequelae, such as disorders of attention and memory. Known as post-concussive symptoms (PCS, these problems can severely disrupt the patient's quality of life. Changes in local spectral power, particularly low-frequency amplitude increases and/or peak alpha slowing have been reported in mTBI, but large-scale connectivity metrics based on inter-regional amplitude correlations relevant for integration and segregation in functional brain networks, and their association with disorders in cognition and behaviour, remain relatively unexplored. Here, we used non-invasive neuroimaging with magnetoencephalography to examine functional connectivity in a resting-state protocol in a group with mTBI (n = 20, and a control group (n = 21. We observed a trend for atypical slow-wave power changes in subcortical, temporal and parietal regions in mTBI, as well as significant long-range increases in amplitude envelope correlations among deep-source, temporal, and frontal regions in the delta, theta, and alpha bands. Subsequently, we conducted an exploratory analysis of patterns of connectivity most associated with variability in secondary symptoms of mTBI, including inattention, anxiety, and depression. Differential patterns of altered resting state neurophysiological network connectivity were found across frequency bands. This indicated that multiple network and frequency specific alterations in large scale brain connectivity may contribute to overlapping cognitive sequelae in mTBI. In conclusion, we show that local spectral power content can be supplemented with measures of correlations in amplitude to define general networks that are atypical in mTBI, and suggest that certain cognitive difficulties are mediated by disturbances in a variety of alterations in network interactions which are differentially

  2. Bolted-connection design

    Science.gov (United States)

    Lawrence A. Soltis; Thomas Lee Wilkinson

    1987-01-01

    Recent failures of bolted connections have raised doubts about our knowledge of their design. Some of the design criteria are based on research conducted more than 50 years ago. This paper compares results found in the literature, using the European Yield Theory as a basis of comparison, to summarize what is known about bolted-connection design and what needs further...

  3. Undifferentiated Connective Tissue Disease

    Science.gov (United States)

    ... Examples of connective tissue diseases include lupus , scleroderma , rheumatoid arthritis , Sjögren's syndrome , myositis and vasculitis . There are many people who have features of connective tissue disease, however, they do not fulfill the diagnostic criteria established for any one disease. In such ...

  4. IDRC Connect User Guide

    International Development Research Centre (IDRC) Digital Library (Canada)

    Kristina Kamichaitis

    2 Jul 2015 ... IDRC Connect es un portal web que permite a los miembros del Equipo del proyecto realizar lo siguiente: ... A todos los miembros del Equipo del proyecto se les otorga acceso a IDRC Connect. Consulte ...... cubrir los costos durante el ciclo de vida de los proyectos activos o hasta 24 meses después de la.

  5. Modeling Structural Brain Connectivity

    DEFF Research Database (Denmark)

    Ambrosen, Karen Marie Sandø

    The human brain consists of a gigantic complex network of interconnected neurons. Together all these connections determine who we are, how we react and how we interpret the world. Knowledge about how the brain is connected can further our understanding of the brain’s structural organization, help...... improve diagnosis, and potentially allow better treatment of a wide range of neurological disorders. Tractography based on diffusion magnetic resonance imaging is a unique tool to estimate this “structural connectivity” of the brain non-invasively and in vivo. During the last decade, brain connectivity...... has increasingly been analyzed using graph theoretic measures adopted from network science and this characterization of the brain’s structural connectivity has been shown to be useful for the classification of populations, such as healthy and diseased subjects. The structural connectivity of the brain...

  6. Generalized connectivity of graphs

    CERN Document Server

    Li, Xueliang

    2016-01-01

    Noteworthy results, proof techniques, open problems and conjectures in generalized (edge-) connectivity are discussed in this book. Both theoretical and practical analyses for generalized (edge-) connectivity of graphs are provided. Topics covered in this book include: generalized (edge-) connectivity of graph classes, algorithms, computational complexity, sharp bounds, Nordhaus-Gaddum-type results, maximum generalized local connectivity, extremal problems, random graphs, multigraphs, relations with the Steiner tree packing problem and generalizations of connectivity. This book enables graduate students to understand and master a segment of graph theory and combinatorial optimization. Researchers in graph theory, combinatorics, combinatorial optimization, probability, computer science, discrete algorithms, complexity analysis, network design, and the information transferring models will find this book useful in their studies.

  7. Handbook of Brain Connectivity

    CERN Document Server

    Jirsa, Viktor K

    2007-01-01

    Our contemporary understanding of brain function is deeply rooted in the ideas of the nonlinear dynamics of distributed networks. Cognition and motor coordination seem to arise from the interactions of local neuronal networks, which themselves are connected in large scales across the entire brain. The spatial architectures between various scales inevitably influence the dynamics of the brain and thereby its function. But how can we integrate brain connectivity amongst these structural and functional domains? Our Handbook provides an account of the current knowledge on the measurement, analysis and theory of the anatomical and functional connectivity of the brain. All contributors are leading experts in various fields concerning structural and functional brain connectivity. In the first part of the Handbook, the chapters focus on an introduction and discussion of the principles underlying connected neural systems. The second part introduces the currently available non-invasive technologies for measuring struct...

  8. an embarrassment of riches or a profusion of confusion

    African Journals Online (AJOL)

    Bradley Smith

    2010-08-12

    Robbie) Robinson. BJuris LLB ... be amended – see Smith Domestic Partnership Rubric 465-467. 10 Clause 4(1) and (2) read with ... multiple unregistered domestic partnerships – see Smith (n 9) 508. 20 Clause 26(1). 21 Clause ...

  9. An embarrassment of riches or a profusion of confusion? an ...

    African Journals Online (AJOL)

    As it stands, South African family law currently holds that the Marriage Act 25 of 1961 applies exclusively to the solemnisation of heterosexual civil marriages while samesex couples have no choice but to formalise their relationships in terms of the Civil Union Act 17 of 2006. In addition, the legal position is complicated by the ...

  10. an embarrassment of riches or a profusion of confusion

    African Journals Online (AJOL)

    Bradley Smith

    2010-08-12

    Aug 12, 2010 ... Bonthuys that when the conscientious objection clauses in the Marriage Act and the Civil Union Act are compared, it becomes clear that the provision in the latter Act is more widely phrased than its counterpart in that it allows objections on the basis of "conscience" and "belief" in addition to those based on ...

  11. Quantifying bicycle network connectivity.

    Science.gov (United States)

    Lowry, Michael; Loh, Tracy Hadden

    2017-02-01

    The intent of this study was to compare bicycle network connectivity for different types of bicyclists and different neighborhoods. Connectivity was defined as the ability to reach important destinations, such as grocery stores, banks, and elementary schools, via pathways or roads with low vehicle volumes and low speed limits. The analysis was conducted for 28 neighborhoods in Seattle, Washington under existing conditions and for a proposed bicycle master plan, which when complete will provide over 700 new bicycle facilities, including protected bike lanes, neighborhood greenways, and multi-use trails. The results showed different levels of connectivity across neighborhoods and for different types of bicyclists. Certain projects were shown to improve connectivity differently for confident and non-confident bicyclists. The analysis showed a positive correlation between connectivity and observed utilitarian bicycle trips. To improve connectivity for the majority of bicyclists, planners and policy-makers should provide bicycle facilities that allow immediate, low-stress access to the street network, such as neighborhood greenways. The analysis also suggests that policies and programs that build confidence for bicycling could greatly increase connectivity. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. Covariant Magnetic Connection Hypersurfaces

    CERN Document Server

    Pegoraro, F

    2016-01-01

    In the single fluid, nonrelativistic, ideal-Magnetohydrodynamic (MHD) plasma description magnetic field lines play a fundamental role by defining dynamically preserved "magnetic connections" between plasma elements. Here we show how the concept of magnetic connection needs to be generalized in the case of a relativistic MHD description where we require covariance under arbitrary Lorentz transformations. This is performed by defining 2-D {\\it magnetic connection hypersurfaces} in the 4-D Minkowski space. This generalization accounts for the loss of simultaneity between spatially separated events in different frames and is expected to provide a powerful insight into the 4-D geometry of electromagnetic fields when ${\\bf E} \\cdot {\\bf B} = 0$.

  13. Fast eigenvector centrality mapping of voxel-wise connectivity in functional magnetic resonance imaging: implementation, validation, and interpretation.

    Science.gov (United States)

    Wink, Alle Meije; de Munck, Jan C; van der Werf, Ysbrand D; van den Heuvel, Odile A; Barkhof, Frederik

    2012-01-01

    Eigenvector centrality mapping (ECM) has recently emerged as a measure to spatially characterize connectivity in functional brain imaging by attributing network properties to voxels. The main obstacle for widespread use of ECM in functional magnetic resonance imaging (fMRI) is the cost of computing and storing the connectivity matrix. This article presents fast ECM (fECM), an efficient algorithm to estimate voxel-wise eigenvector centralities from fMRI time series. Instead of explicitly storing the connectivity matrix, fECM computes matrix-vector products directly from the data, achieving high accelerations for computing voxel-wise centralities in fMRI at standard resolutions for multivariate analyses, and enabling high-resolution analyses performed on standard hardware. We demonstrate the validity of fECM at cluster and voxel levels, using synthetic and in vivo data. Results from synthetic data are compared to the theoretical gold standard, and local centrality changes in fMRI data are measured after experimental intervention. A simple scheme is presented to generate time series with prescribed covariances that represent a connectivity matrix. These time series are used to construct a 4D dataset whose volumes consist of separate regions with known intra- and inter-regional connectivities. The fECM method is tested and validated on these synthetic data. Resting-state fMRI data acquired after real-versus-sham repetitive transcranial magnetic stimulation show fECM connectivity changes in resting-state network regions. A comparison of analyses with and without accounting for motion parameters demonstrates a moderate effect of these parameters on the centrality estimates. Its computational speed and statistical sensitivity make fECM a good candidate for connectivity analyses of multimodality and high-resolution functional neuroimaging data.

  14. Hydrologically Connected Road Segments

    Data.gov (United States)

    Vermont Center for Geographic Information — Link it ArcGIS Item is HERE.The connectivity layer was created to assist municipalities in preparing for the forthcoming DEC Municipal Roads General Permit in 2018....

  15. Connecting with climate science

    Science.gov (United States)

    2017-03-01

    Protecting science-based policymaking requires engaging the public, not politicians. Cultural institutions and the arts provide non-partisan platforms for communication that can connect scientific climate change data to people's lives.

  16. Connected vehicle applications : environment.

    Science.gov (United States)

    2016-01-01

    The U.S. Department of Transportation has developed a number of connected vehicle environmental : applications, including the Applications for the Environment Real-Time Information Synthesis (AERIS) : research program applications and road weather ap...

  17. Connecting with Your Preteen

    Science.gov (United States)

    ... español Comprendiendo a su hijo(a) preadolescente Staying connected as kids approach the teen years and become ... along on his or her run. Washing the car, baking cookies, renting movies, watching a favorite TV ...

  18. How connected vehicles work.

    Science.gov (United States)

    2011-01-01

    Connected vehicles have the potential to transform the way Americans travel through the creation : of a safe, interoperable wireless communications networka system that includes cars, buses, : trucks, trains, traffic signals, cell phones, and othe...

  19. JAVA based data connectivity

    OpenAIRE

    Garingo, Gary D

    1997-01-01

    Current web database connectivity solutions lack an object oriented architecture for Java applications. In particular, Java is object oriented and most legacy databases are relational. This thesis proposes a design and implementation of an object oriented Java database class hierarchy for relational database interfaces. The work reported here consists of: (1) analysis of Java Database Connectivity specification, (2) discussion of two-tier and three-tier architectures for database systems, (3)...

  20. Changes of metabolism and functional connectivity in late-onset deafness: Evidence from cerebral 18F-FDG-PET.

    Science.gov (United States)

    Verger, Antoine; Roman, Stéphane; Chaudat, Rose-May; Felician, Olivier; Ceccaldi, Mathieu; Didic, Mira; Guedj, Eric

    2017-09-01

    Hearing loss is known to impact brain function. The aim of this study was to characterize cerebral metabolic Positron Emission Tomography (PET) changes in elderly patients fulfilling criteria for cochlear implant and investigate the impact of hearing loss on functional connectivity. Statistical Parametric Mapping-T-scores-maps comparisons of 18F-FDG-PET of 27 elderly patients fulfilling criteria for cochlear implant for hearing loss (best-aided speech intelligibility lower or equal to 50%) and 27 matched healthy subjects (p < 0.005, corrected for volume extent) were performed. Metabolic connectivity was evaluated through interregional correlation analysis. Patients were found to have decreased metabolism within the right associative auditory cortex, while increased metabolism was found in prefrontal areas, pre- and post-central areas, the cingulum and the left inferior parietal gyrus. The right associative auditory cortex was integrated into a network of increased metabolic connectivity that included pre- and post-central areas, the cingulum, the right inferior parietal gyrus, as well as the striatum on both sides. Metabolic values of the right associative auditory cortex and left inferior parietal gyrus were positively correlated with performance on neuropsychological test scores. These findings provide further insight into the reorganization of the connectome through sensory loss and compensatory mechanisms in elderly patients with severe hearing loss. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. Connectable solar air collectors

    Energy Technology Data Exchange (ETDEWEB)

    Oestergaard Jensen, S.; Bosanac, M.

    2002-02-01

    The project has proved that it is possible to manufacture solar air collector panels, which in an easy way can be connected into large collector arrays with integrated ducting without loss of efficiency. The developed connectable solar air collectors are based on the use of matrix absorbers in the form of perforated metal sheets. Three interconnected solar air collectors of the above type - each with an transparent area of approx. 3 m{sup 2} - was tested and compared with parallel tests on two single solar air collectors also with a transparent area of approx. 3 m{sup 2} One of the single solar air collectors has an identical absorber as the connectable solar air collectors while the absorber of the other single solar air collector was a fibre cloth. The efficiency of the three solar air collectors proved to be almost identical in the investigated range of mass flow rates and temperature differences. The solar air collectors further proved to be very efficient - as efficient as the second most efficient solar air collectors tested in the IEA task 19 project Solar Air Systems. Some problems remain although to be solved: the pressure drop across especially the connectable solar air collectors is too high - mainly across the inlets of the solar air collectors. It should, however, be possible to considerably reduce the pressure losses with a more aerodynamic design of the inlet and outlet of the solar air collectors; The connectable solar air collectors are easy connectable but the air tightness of the connections in the present form is not good enough. As leakage leads to lower efficiencies focus should be put on making the connections more air tight without loosing the easiness in connecting the solar air collectors. As a spin off of the project a simple and easy way to determine the efficiency of solar, air collectors for pre-heating of fresh air has been validated. The simple method of determining the efficiency has with success been compared with an advance method

  2. Broca's area - thalamic connectivity.

    Science.gov (United States)

    Bohsali, Anastasia A; Triplett, William; Sudhyadhom, Atchar; Gullett, Joseph M; McGregor, Keith; FitzGerald, David B; Mareci, Thomas; White, Keith; Crosson, Bruce

    2015-02-01

    Broca's area is crucially involved in language processing. The sub-regions of Broca's area (pars triangularis, pars opercularis) presumably are connected via corticocortical pathways. However, growing evidence suggests that the thalamus may also be involved in language and share some of the linguistic functions supported by Broca's area. Functional connectivity is thought to be achieved via corticothalamic/thalamocortical white matter pathways. Our study investigates structural connectivity between Broca's area and the thalamus, specifically ventral anterior nucleus and pulvinar. We demonstrate that Broca's area shares direct connections with these thalamic nuclei and suggest a local Broca's area-thalamus network potentially involved in linguistic processing. Thalamic connectivity with Broca's area may serve to selectively recruit cortical regions storing multimodal features of lexical items and to bind them together during lexical-semantic processing. In addition, Broca's area-thalamic circuitry may enable cortico-thalamo-cortical information transfer and modulation between BA 44 and 45 during language comprehension and production. Published by Elsevier Inc.

  3. Skeletal muscle connective tissue

    DEFF Research Database (Denmark)

    Brüggemann, Dagmar Adeline

      The connective tissue content of skeletal muscle is believed to be the major factor responsible for defining the eating quality of different meat cuts, although attempts to correlate quantifications based on traditional histological methods have not as yet been able to prove this relation...... composition, the organizational structure of connective tissue, the role of connective tissue in muscle contraction and the generation of force, metabolic regulation of arterial structure focusing on associated collagen changes, and a new highly-specific technique for following in three-dimensions changes...... in the structure of fibrous collagen and myofibers at high-resolution. The results demonstrate that the collagen composition in the extra cellular matrix of Gadus morhua fish muscle is much more complex than previously anticipated, as it contains type III, IV, V  and VI collagen in addition to type I. The vascular...

  4. Connectivity and superconductivity

    CERN Document Server

    Rubinstein, Jacob

    2000-01-01

    The motto of connectivity and superconductivity is that the solutions of the Ginzburg--Landau equations are qualitatively influenced by the topology of the boundaries, as in multiply-connected samples. Special attention is paid to the "zero set", the set of the positions (also known as "quantum vortices") where the order parameter vanishes. The effects considered here usually become important in the regime where the coherence length is of the order of the dimensions of the sample. It takes the intuition of physicists and the awareness of mathematicians to find these new effects. In connectivity and superconductivity, theoretical and experimental physicists are brought together with pure and applied mathematicians to review these surprising results. This volume is intended to serve as a reference book for graduate students and researchers in physics or mathematics interested in superconductivity, or in the Schrödinger equation as a limiting case of the Ginzburg--Landau equations.

  5. Best connected rectangular arrangements

    Directory of Open Access Journals (Sweden)

    Krishnendra Shekhawat

    2016-03-01

    Full Text Available It can be found quite often in the literature that many well-known architects have employed either the golden rectangle or the Fibonacci rectangle in their works. On contrary, it is rare to find any specific reason for using them so often. Recently, Shekhawat (2015 proved that the golden rectangle and the Fibonacci rectangle are one of the best connected rectangular arrangements and this may be one of the reasons for their high presence in architectural designs. In this work we present an algorithm that generates n-4 best connected rectangular arrangements so that the proposed solutions can be further used by architects for their designs.

  6. Age-related changes in functional connectivity of cerebellar PlV: a FDG PET study

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Sang Soo; Yoon, Eun Jin; Bang, Seong Ae; Park, Hyun Soo; Kim, Yu Kyeong; Kim, Sang Eun [Seoul National Univ. College of Medicine, Seoul (Korea, Republic of)

    2007-07-01

    The cerebellum is known to have strong connection with cerebral cortex, and it shows the greatest mean shrinkage with aging. Changes in functional connectivity between cerebellum and cortical and subcortical cerebral areas possibly occur in normal aging. In this study, we tested changes of interregional connection between cerebellar posterior inferior vermis (PIV) and cerebrum in healthy subjects divided in three classes of age group (young: 20-30, middle age: 40-50, elderly: over 60 years) using FDG PET. 211 healthy subjects (age, 20-82 y; 134 female) were studied with resting-state brain glucose utilization measured by FDG-PET, cerebellar PIV activity after count-normalization to the whole gray matter mean count was extracted. Using PIV count as a 'seed', the maps of cross-correlation coefficients were computed by measuring the correlation between 'seed' and all the other brain voxels (P < 0.001 uncorrected, k = 100). Across all age groups, positive correlations of metabolic activity in the cerebellar PIV showed in cerebellum itself and bilateral thalamus. An extended positive correlation in cuneus which is served for visual information processing was observed in middle aged and elderly group differently from the young group. Also, in elderly group, this correlation was observed in the frontal areas such as right orbital and precentral gyri. Negative correlation implicating mutual inhibition between the areas was also founded in prefrontal and cingulate cortices and temporoparietal association areas. Comparing with the young group, in theses areas, enlarged negative correlations was founded with aging. We identified age related changes in cerebrocerebellar communication loop which reflect changes in local neuroplasticity in the normal aging brain. Present result may have implication for understanding the functional decline of cerebellum related cognitive ability as well as the deficit of motor coordination in normal aging and its compensation

  7. Reduced frontal-subcortical white matter connectivity in association with suicidal ideation in major depressive disorder

    Science.gov (United States)

    Myung, W; Han, C E; Fava, M; Mischoulon, D; Papakostas, G I; Heo, J-Y; Kim, K W; Kim, S T; Kim, D J H; Kim, D K; Seo, S W; Seong, J-K; Jeon, H J

    2016-01-01

    Major depressive disorder (MDD) and suicidal behavior have been associated with structural and functional changes in the brain. However, little is known regarding alterations of brain networks in MDD patients with suicidal ideation. We investigated whether or not MDD patients with suicidal ideation have different topological organizations of white matter networks compared with MDD patients without suicidal ideation. Participants consisted of 24 patients with MDD and suicidal ideation, 25 age- and gender-matched MDD patients without suicidal ideation and 31 healthy subjects. A network-based statistics (NBS) and a graph theoretical analysis were performed to assess differences in the inter-regional connectivity. Diffusion tensor imaging (DTI) was performed to assess topological changes according to suicidal ideation in MDD patients. The Scale for Suicide Ideation (SSI) and the Korean version of the Barrett Impulsiveness Scale (BIS) were used to assess the severity of suicidal ideation and impulsivity, respectively. Reduced structural connectivity in a characterized subnetwork was found in patients with MDD and suicidal ideation by utilizing NBS analysis. The subnetwork included the regions of the frontosubcortical circuits and the regions involved in executive function in the left hemisphere (rostral middle frontal, pallidum, superior parietal, frontal pole, caudate, putamen and thalamus). The graph theoretical analysis demonstrated that network measures of the left rostral middle frontal had a significant positive correlation with severity of SSI (r=0.59, P=0.02) and BIS (r=0.59, P=0.01). The total edge strength that was significantly associated with suicidal ideation did not differ between MDD patients without suicidal ideation and healthy subjects. Our findings suggest that the reduced frontosubcortical circuit of structural connectivity, which includes regions associated with executive function and impulsivity, appears to have a role in the emergence of suicidal

  8. Mathematics Connection: Editorial Policies

    African Journals Online (AJOL)

    Focus and Scope. MATHEMATICS CONNECTION aims at providing a forum to promote the development of Mathematics Education in Ghana. Articles that seek to enhance the teaching and/or learning of mathematics at all levels of the educational system are welcome ...

  9. The CORALS Connection

    Science.gov (United States)

    Plankis, Brian; Klein, Carolyn

    2010-01-01

    The Ocean, Reefs, Aquariums, Literacy, and Stewardship (CORALS) research program helps students connect global environmental issues to local concerns and personal choices. During the 18-week program, students strengthen their understanding of coral reef decline through a classroom aquarium activity, communicate with science experts, and create…

  10. Multiply Connected Universes

    OpenAIRE

    Sidharth, B. G.

    2006-01-01

    It is now generally believed that our observable universe is one amongst a very large number - may be $10^{500}$ - of parallel universes. Following the author's own model in this context, we argue that this conglomeration of universes defines a multiply connected super space.

  11. Connecting textual segments

    DEFF Research Database (Denmark)

    Brügger, Niels

    2017-01-01

    history than just the years of the emergence of the web, the chapter traces the history of how segments of text have deliberately been connected to each other by the use of specific textual and media features, from clay tablets, manuscripts on parchment, and print, among others, to hyperlinks on stand......-alone computers and in local and global digital networks....

  12. Our Cosmic Connection

    Science.gov (United States)

    Young, Donna L.

    2005-01-01

    To help students understand the connection that Earth and the solar system have with the cosmic cycles of stellar evolution, and to give students an appreciation of the beauty and elegance of celestial phenomena, the Chandra X-Ray Center (CXC) educational website contains a stellar evolution module that is available free to teachers. In this…

  13. Long-Distance Connection

    Science.gov (United States)

    Clift, Kate

    2010-01-01

    Transient populations, cultural diversity, language barriers, competing loyalties, and geographic separation are just some of the challenges international schools face in communicating and connecting with their alumni. And these issues are not going to get any easier as the sector grows. Communicating effectively with large, diverse groups of…

  14. IDRC Connect User Guide

    International Development Research Centre (IDRC) Digital Library (Canada)

    Kristina Kamichaitis

    IDRC believes that publicly funded research should be freely and openly available. We also believe that open access research facilitates access to knowledge world-wide. Open access is critical to empowerment through knowledge. IDRC Connect helps realize IDRC's Open Access Policy by facilitating the timely ...

  15. IDRC Connect User Guide

    International Development Research Centre (IDRC) Digital Library (Canada)

    Kristina Kamichaitis

    Digital Library under the Creative Commons Attribution (CC BY) license agreement. Submission Notifications. IDRC Connect automatically sends notifications via email to users when a Project Report or Project. Output is submitted. Notifications are sent to the submitter, the relevant Program Officer, the Project. Leader, and ...

  16. Revisiting city connectivity

    NARCIS (Netherlands)

    Mans, U.

    2014-01-01

    This article introduces a new perspective on city connectivity in order to analyze non-hub cities and their position in the world economy. The author revisits the different approaches discussed in the Global Commodity Chains (GCC), Global Production Networks (GPN) and World City Network (WCN)

  17. Abnormalities in fronto-striatal connectivity within language networks relate to differences in grey-matter heterogeneity in Asperger syndrome☆

    Science.gov (United States)

    Radulescu, Eugenia; Minati, Ludovico; Ganeshan, Balaji; Harrison, Neil A.; Gray, Marcus A.; Beacher, Felix D.C.C.; Chatwin, Chris; Young, Rupert C.D.; Critchley, Hugo D.

    2013-01-01

    Asperger syndrome (AS) is an Autism Spectrum Disorder (ASD) characterised by qualitative impairment in the development of emotional and social skills with relative preservation of general intellectual abilities, including verbal language. People with AS may nevertheless show atypical language, including rate and frequency of speech production. We previously observed that abnormalities in grey matter homogeneity (measured with texture analysis of structural MR images) in AS individuals when compared with controls are also correlated with the volume of caudate nucleus. Here, we tested a prediction that these distributed abnormalities in grey matter compromise the functional integrity of brain networks supporting verbal communication skills. We therefore measured the functional connectivity between caudate nucleus and cortex during a functional neuroimaging study of language generation (verbal fluency), applying psycho-physiological interaction (PPI) methods to test specifically for differences attributable to grey matter heterogeneity in AS participants. Furthermore, we used dynamic causal modelling (DCM) to characterise the causal directionality of these differences in interregional connectivity during word production. Our results revealed a diagnosis-dependent influence of grey matter heterogeneity on the functional connectivity of the caudate nuclei with right insula/inferior frontal gyrus and anterior cingulate, respectively with the left superior frontal gyrus and right precuneus. Moreover, causal modelling of interactions between inferior frontal gyri, caudate and precuneus, revealed a reliance on bottom-up (stimulus-driven) connections in AS participants that contrasted with a dominance of top-down (cognitive control) connections from prefrontal cortex observed in control participants. These results provide detailed support for previously hypothesised central disconnectivity in ASD and specify discrete brain network targets for diagnosis and therapy in ASD

  18. Abnormalities in fronto-striatal connectivity within language networks relate to differences in grey-matter heterogeneity in Asperger syndrome.

    Science.gov (United States)

    Radulescu, Eugenia; Minati, Ludovico; Ganeshan, Balaji; Harrison, Neil A; Gray, Marcus A; Beacher, Felix D C C; Chatwin, Chris; Young, Rupert C D; Critchley, Hugo D

    2013-01-01

    Asperger syndrome (AS) is an Autism Spectrum Disorder (ASD) characterised by qualitative impairment in the development of emotional and social skills with relative preservation of general intellectual abilities, including verbal language. People with AS may nevertheless show atypical language, including rate and frequency of speech production. We previously observed that abnormalities in grey matter homogeneity (measured with texture analysis of structural MR images) in AS individuals when compared with controls are also correlated with the volume of caudate nucleus. Here, we tested a prediction that these distributed abnormalities in grey matter compromise the functional integrity of brain networks supporting verbal communication skills. We therefore measured the functional connectivity between caudate nucleus and cortex during a functional neuroimaging study of language generation (verbal fluency), applying psycho-physiological interaction (PPI) methods to test specifically for differences attributable to grey matter heterogeneity in AS participants. Furthermore, we used dynamic causal modelling (DCM) to characterise the causal directionality of these differences in interregional connectivity during word production. Our results revealed a diagnosis-dependent influence of grey matter heterogeneity on the functional connectivity of the caudate nuclei with right insula/inferior frontal gyrus and anterior cingulate, respectively with the left superior frontal gyrus and right precuneus. Moreover, causal modelling of interactions between inferior frontal gyri, caudate and precuneus, revealed a reliance on bottom-up (stimulus-driven) connections in AS participants that contrasted with a dominance of top-down (cognitive control) connections from prefrontal cortex observed in control participants. These results provide detailed support for previously hypothesised central disconnectivity in ASD and specify discrete brain network targets for diagnosis and therapy in ASD.

  19. Connected Cubic Network Graph

    Directory of Open Access Journals (Sweden)

    Burhan Selçuk

    2017-06-01

    Full Text Available Hypercube is a popular interconnection network. Due to the popularity of hypercube, more researchers pay a great effort to develop the different variants of hypercube. In this paper, we have proposed a variant of hypercube which is called as “Connected Cubic Network Graphs”, and have investigated the Hamilton-like properties of Connected Cubic Network Graphs (CCNG. Firstly, we defined CCNG and showed the characteristic analyses of CCNG. Then, we showed that the CCNG has the properties of Hamilton graph, and can be labeled using a Gray coding based recursive algorithm. Finally, we gave the comparison results, a routing algorithm and a bitonic sort algorithm for CCNG. In case of sparsity and cost, CCNG is better than Hypercube.

  20. The Will to Connection

    DEFF Research Database (Denmark)

    Jensen, Ole B.

    for the importance of understanding the ‘will to connection’ as a crucial human feature. Since then much technological development has taken place and today we need to engage with this from the vantage point of the ‘mobilities turn’ (e.g. represented by Adey 2010, Cresswell 2006, Sheller & Urry 2006, and Urry 2007......). Crucially, ‘visibly impressing the path into the surface of the earth’ is no longer sufficient evidence of connections and interactions since networked technologies create connections by ‘invisible’ linkages across time and space suggesting the we need to add ‘digital connectivity’ to ‘physical proximity......’ in order fully to comprehend contemporary mobilities. This paper argues for a situational and everyday life perspective termed ‘Staging Mobilities’ (Jensen, forthcoming). It draws in particular on the works of Goffman and has been applied to mobility research earlier (Jensen 2010a, 2010b). According...

  1. The CONNECT project

    DEFF Research Database (Denmark)

    Assaf, Yaniv; Alexander, Daniel C; Jones, Derek K

    2013-01-01

    Of Neuroimagers for the Non-invasive Exploration of brain Connectivity and Tracts) project aimed to combine tractography and micro-structural measures of the living human brain in order to obtain a better estimate of the connectome, while also striving to extend validation of these measurements. This paper...... summarizes the project and describes the perspective of using micro-structural measures to study the connectome....

  2. Energy storage connection system

    Science.gov (United States)

    Benedict, Eric L.; Borland, Nicholas P.; Dale, Magdelena; Freeman, Belvin; Kite, Kim A.; Petter, Jeffrey K.; Taylor, Brendan F.

    2012-07-03

    A power system for connecting a variable voltage power source, such as a power controller, with a plurality of energy storage devices, at least two of which have a different initial voltage than the output voltage of the variable voltage power source. The power system includes a controller that increases the output voltage of the variable voltage power source. When such output voltage is substantially equal to the initial voltage of a first one of the energy storage devices, the controller sends a signal that causes a switch to connect the variable voltage power source with the first one of the energy storage devices. The controller then causes the output voltage of the variable voltage power source to continue increasing. When the output voltage is substantially equal to the initial voltage of a second one of the energy storage devices, the controller sends a signal that causes a switch to connect the variable voltage power source with the second one of the energy storage devices.

  3. Finding significantly connected voxels based on histograms of connection strengths

    DEFF Research Database (Denmark)

    Kasenburg, Niklas; Pedersen, Morten Vester; Darkner, Sune

    2016-01-01

    We explore a new approach for structural connectivity based segmentations of subcortical brain regions. Connectivity based segmentations are usually based on fibre connections from a seed region to predefined target regions. We present a method for finding significantly connected voxels based...... on the distribution of connection strengths. Paths from seed voxels to all voxels in a target region are obtained from a shortest-path tractography. For each seed voxel we approximate the distribution with a histogram of path scores. We hypothesise that the majority of estimated connections are false......-positives and that their connection strength is distributed differently from true-positive connections. Therefore, an empirical null-distribution is defined for each target region as the average normalized histogram over all voxels in the seed region. Single histograms are then tested against the corresponding null...

  4. Connected networks economy

    Energy Technology Data Exchange (ETDEWEB)

    Hamerak, K.

    1981-05-05

    Two foremost requirements for interconnected power systems are: constancy of frequency and constancy of voltage. Because there is a rigid relation between main frequency and the number of revolutions of the synchronous generators, and this leads to active load alterations in the case of frequency changes of the network, there is a need for control systems for power networks. In practice they are designed for automatic operation. For control of the number of revolutions of turbines proportional controllers are the most useful. Autocontrol also has an advantageous influence on frequency stability. Peak loads in connected networks are covered by pumping storage power plants.

  5. Heritable Disorders of Connective Tissue

    Science.gov (United States)

    ... rare. Common heritable disorders of connective tissue include: Ehlers-Danlos syndrome mostly affects the skin and joints. Connective ... of America, Inc. Website: https://www.debra.org Ehlers-Danlos National Foundation Website: https://www.ednf.org/ National ...

  6. An Electroencephalography Network and Connectivity Analysis for Deception in Instructed Lying Tasks

    Science.gov (United States)

    Wang, Yue; Ng, Wu Chun; Ng, Khoon Siong; Yu, Ke; Wu, Tiecheng; Li, Xiaoping

    2015-01-01

    Deception is an impactful social event that has been the focus of an abundance of researches over recent decades. In this paper, an electroencephalography (EEG) study is presented regarding the cognitive processes of an instructed liar/truth-teller during the time window of stimulus (question) delivery period (SDP) prior to their deceptive/truthful responses towards questions related to authentic (WE: with prior experience) and fictional experience (NE: no prior experience). To investigate deception in non-experienced events, the subjects were given stimuli in a mock interview scenario that induced them to fabricate lies. To analyze the data, frequency domain network and connectivity analysis was performed in the source space in order to provide a more systematic level understanding of deception during SDP. This study reveals several groups of neuronal generators underlying both the instructed lying (IL) and the instructed truth-telling (IT) conditions for both tasks during the SDP. Despite the similarities existed in these group components, significant differences were found in the intra- and inter-group connectivity between the IL and IT conditions in either task. Additionally, the response time was found to be positively correlated with the clustering coefficient of the inferior frontal gyrus (44R) in the WE-IL condition and positively correlated with the clustering coefficient of the precuneus (7L) and the angular gyrus (39R) in the WE-IT condition. However, the response time was found to be marginally negatively correlated with the clustering coefficient of the secondary auditory cortex (42L) in the NE-IL condition and negatively correlated with the clustering coefficient of the somatosensory association cortex (5L, R) in the NE-IT condition. Therefore, these results provide complementary and intuitive evidence for the differences between the IL and IT conditions in SDP for two types of deception tasks, thus elucidating the electrophysiological mechanisms

  7. Impaired functional connectivity of brain reward circuitry in patients with schizophrenia and cannabis use disorder: Effects of cannabis and THC.

    Science.gov (United States)

    Fischer, Adina S; Whitfield-Gabrieli, Susan; Roth, Robert M; Brunette, Mary F; Green, Alan I

    2014-09-01

    Cannabis use disorder (CUD) occurs in up to 42% of patients with schizophrenia and substantially worsens disease progression. The basis of CUD in schizophrenia is unclear and available treatments are rarely successful at limiting cannabis use. We have proposed that a dysregulated brain reward circuit (BRC) may underpin cannabis use in these patients. In the present pilot study, we used whole-brain seed-to-voxel resting state functional connectivity (rs-fc) to examine the BRC of patients with schizophrenia and CUD, and to explore the effects of smoked cannabis and orally administered delta-9-tetrahydrocannabinol (THC) on the BRC. 12 patients with schizophrenia and CUD and 12 control subjects each completed two fMRI resting scans, with patients administered either a 3.6% THC cannabis cigarette (n=6) or a 15 mg THC capsule (n=6) prior to their second scan. Results revealed significantly reduced connectivity at baseline in patients relative to controls, with most pronounced hypoconnectivity found between the nucleus accumbens and prefrontal cortical BRC regions (i.e., anterior prefrontal cortex, orbitofrontal cortex, and anterior cingulate cortex). Both cannabis and THC administration increased connectivity between these regions, in direct correlation with increases in plasma THC levels. This study is the first to investigate interregional connectivity of the BRC and the effects of cannabis and THC on this circuit in patients with schizophrenia and CUD. The findings from this pilot study support the use of rs-fc as a means of measuring the integrity of the BRC and the effects of pharmacologic agents acting on this circuit in patients with schizophrenia and CUD. Copyright © 2014. Published by Elsevier B.V.

  8. Alterations of Intrinsic Brain Connectivity Patterns in Depression and Bipolar Disorders: A Critical Assessment of Magnetoencephalography-Based Evidence

    Science.gov (United States)

    Alamian, Golnoush; Hincapié, Ana-Sofía; Combrisson, Etienne; Thiery, Thomas; Martel, Véronique; Althukov, Dmitrii; Jerbi, Karim

    2017-01-01

    Despite being the object of a thriving field of clinical research, the investigation of intrinsic brain network alterations in psychiatric illnesses is still in its early days. Because the pathological alterations are predominantly probed using functional magnetic resonance imaging (fMRI), many questions about the electrophysiological bases of resting-state alterations in psychiatric disorders, particularly among mood disorder patients, remain unanswered. Alongside important research using electroencephalography (EEG), the specific recent contributions and future promise of magnetoencephalography (MEG) in this field are not fully recognized and valued. Here, we provide a critical review of recent findings from MEG resting-state connectivity within major depressive disorder (MDD) and bipolar disorder (BD). The clinical MEG resting-state results are compared with those previously reported with fMRI and EEG. Taken together, MEG appears to be a promising but still critically underexploited technique to unravel the neurophysiological mechanisms that mediate abnormal (both hyper- and hypo-) connectivity patterns involved in MDD and BD. In particular, a major strength of MEG is its ability to provide source-space estimations of neuromagnetic long-range rhythmic synchronization at various frequencies (i.e., oscillatory coupling). The reviewed literature highlights the relevance of probing local and interregional rhythmic synchronization to explore the pathophysiological underpinnings of each disorder. However, before we can fully take advantage of MEG connectivity analyses in psychiatry, several limitations inherent to MEG connectivity analyses need to be understood and taken into account. Thus, we also discuss current methodological challenges and outline paths for future research. MEG resting-state studies provide an important window onto perturbed spontaneous oscillatory brain networks and hence supply an important complement to fMRI-based resting-state measurements in

  9. Parcellating connectivity in spatial maps

    OpenAIRE

    Baldassano, Christopher; Beck, Diane M.; Fei-Fei, Li

    2014-01-01

    A common goal in biological sciences is to model a complex web of connections using a small number of interacting units. We present a general approach for dividing up elements in a spatial map based on their connectivity properties, allowing for the discovery of local regions underlying large-scale connectivity matrices. Our method is specifically designed to respect spatial layout and identify locally-connected clusters, corresponding to plausible coherent units such as strings of adjacent D...

  10. LHCb connects its pipes

    CERN Multimedia

    2006-01-01

    Two weeks ago the first beryllium section of the LHCb beam vacuum chamber was installed. This three-day operation, after requiring lengthy preparation work, demanded patience and precision as the first of four sections of the beampipe was connected to the vertex locator (VeLo) vacuum vessel. The AT-VAC Group with the collaboration of PH/LBD, including Gloria Corti, Tatsuya Nakada, Patrice Mermet, Delios Ramos, Frans Mul, Bruno Versollato, Bernard Corajod, and Raymond Veness. (Not pictured: Adriana Rossi and Laurent Bouvet) This first installed section is composed of a nearly two-metre long conical tube of one-millimetre thick beryllium and of a thin spherical-shaped window, 800 millimeter diameter, made of an aluminum alloy, and has the appearance of a mushroom lying on its side. The window is connected to the conical part of the beampipe through an aluminum alloy bellow, which is needed to allow for mechanical alignment once the assembly is installed. Beryllium was chosen as the material for 12 m of the 19...

  11. Airport industry connectivity report: 2015

    NARCIS (Netherlands)

    Boonekamp, T.; Lieshout, R.; Burghouwt, G.

    2015-01-01

    This report is an update of the 'Airport Industry Connectivity Report 2004-2014'. It's focused on more recent developments and charting how Europe’s connectivity has evolved over the past 12 months. Airport connectivity is an increasingly discussed topic in European policy circles. With good reason.

  12. Line bundles and flat connections

    Indian Academy of Sciences (India)

    Calabi–Yau threefold; torsion; cocompact lattice; unitary representation. 2000 Mathematics Subject Classification. 81T30, 14D21, 53C07. 1. Stable bundles and unitary flat connections. 1.1 Admitting flat connections. Let X be a compact connected complex manifold of complex dimension δ. Let ω be the. (1, 1)-form on X ...

  13. Quick-Connect Nut

    Science.gov (United States)

    1999-01-01

    Marshall Space Flight Center (MSFC) has developed a specially-designed nut, called the Quick-Connect Nut, for quick and easy assembly of components in the harsh environment of space, as in assembly of International Space Station. The design permits nuts to be installed simply by pushing them onto standard bolts, then giving a quick twist. To remove, they are unscrewed like conventional nuts. Possible applications include the mining industry for erecting support barriers, assembling underwater oil drilling platforms, fire-fighting equipment, scaffolding, assembly-line machinery, industrial cranes, and even changing lug nuts on race cars. The speed of assembly can make the difference between life and death in different aspects of life on Earth.

  14. Practicing (Dis)connections

    DEFF Research Database (Denmark)

    day-to-day character of the work practices entailed, tracing their at once embedded, yet, distributed and disparate – (dis)connected – configurations. In the course of an MRI exam, from the screening of the patient to the scanning itself, and onto the subsequent processing and analysis of the images...... informed study of a relatively routinized and film-based clinical Magnetic Resonance Imaging (MRI) practice of the brain and spine at a hospital neuroradiology department, the paper draws on Bowker and Star’s (1999) notion of infrastructural inversion, to explore the seemingly settled and relatively stable......, imaging practitioners employ and juxtapose a variety of materials and means to frame and guide their inquiry. These may range from the initial clinical presentation of the patient’s referring department, to already available MRIs, CTs or X-rays of the patient. These elements may originate from far removed...

  15. Power converter connection configuration

    Science.gov (United States)

    Beihoff, Bruce C.; Kehl, Dennis L.; Gettelfinger, Lee A.; Kaishian, Steven C.; Phillips, Mark G.; Radosevich, Lawrence D.

    2008-11-11

    EMI shielding is provided for power electronics circuits and the like via a direct-mount reference plane support and shielding structure. The thermal support may receive one or more power electronic circuits. The support may aid in removing heat from the circuits through fluid circulating through the support. The support forms a shield from both external EMI/RFI and from interference generated by operation of the power electronic circuits. Features may be provided to permit and enhance connection of the circuitry to external circuitry, such as improved terminal configurations. Modular units may be assembled that may be coupled to electronic circuitry via plug-in arrangements or through interface with a backplane or similar mounting and interconnecting structures.

  16. Mesoscale Connections Summer 2017

    Energy Technology Data Exchange (ETDEWEB)

    Kippen, Karen Elizabeth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Bourke, Mark Andrew M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-06-21

    Our challenge derives from the fact that in metals or explosives grains, interfaces and defects control engineering performance in ways that are neither amenable to continuum codes (which fail to rigorously describe the heterogeneities derived from microstructure) nor computationally tractable to first principles atomistic calculations. This is a region called the mesoscale, which stands at the frontier of our desire to translate fundamental science insights into confidence in aging system performance over the range of extreme conditions relevant in a nuclear weapon. For dynamic problems, the phenomena of interest can require extremely good temporal resolutions. A shock wave traveling at 1000 m/s (or 1 mm/μs) passes through a grain with a diameter of 1 micron in a nanosecond (10-9 sec). Thus, to observe the mesoscale phenomena—such as dislocations or phase transformations—as the shock passes, temporal resolution better than picoseconds (10-12 sec) may be needed. As we anticipate the science challenges over the next decade, experimental insights on material performance at the micron spatial scale with picosecond temporal resolution—at the mesoscale— are a clear challenge. This is a challenge fit for Los Alamos in partnership with our sister labs and academia. Mesoscale Connections will draw attention to our progress as we tackle the mesoscale challenge. We hope you like it and encourage suggestions of content you are interested in.

  17. (UnCommonly Connected

    Directory of Open Access Journals (Sweden)

    Emily M. Hodge

    2016-11-01

    Full Text Available As states continue to implement the Common Core State Standards (CCSS, state educational agencies (SEAs are providing professional development and curricular resources to help districts and teachers understand the standards. However, little is known about the resources SEAs endorse, the states and/or organizations sponsoring these resources, and how states and organizations are connected. This study investigates the secondary English/language arts resources provided by 51 SEAs (2,023 resources sponsored by 51 SEAs and 262 intermediary organizations. Social network analysis of states and sponsoring organizations revealed a core-periphery network in which certain states and organizations were frequently named as the sponsors of resources, while other organizations were named as resource sponsors by only one state. SEAs are providing a variety of types of resources, including professional development, curriculum guidelines, articles, and instructional aids. This study offers insight into the most influential actors providing CCSS resources at the state level, as well as how SEAs are supporting instructional capacity through the resources they provide for teachers.

  18. ASSESSING LONGITUDINAL THERMAL CONNECTIVITY ...

    Science.gov (United States)

    Water temperature is a key driver of ecological processes in aquatic environments and can influence biological connectivity among riverine habitats. Riverine fish and other mobile aquatic species often must navigate a variety of physical barriers such as dams and culverts. For Pacific salmon, warm water can also pose barriers to migration, but the presence of patches of cooler water within rivers can serve as important refuges and potentially as stepping stones at times of day when temperatures are elsewhere unsuitable along the migratory corridor. Rising water temperature associated with climate change has become a major conservation concern for freshwater species and poses challenges for natural resource managers who must consider multiple factors in addition to uncertainty in climate predictions. Thermal refuges can contribute to watershed-scale thermal resilience and are increasingly considered in water quality regulations; however, monitoring such refuges and effectively operationalizing the concept for management has proved difficult. We review what is known about use of thermal refuges by coldwater fishes in natural systems, and then we present two case study applications in which we characterize thermal patterns in rivers (e.g., the frequency, size, spacing, and location of thermal patches) and consider effects on salmon in a management context. In our first example, we illustrate methods for quantifying spatial heterogeneity in stream temperatures at bi

  19. Transnational Connections and Multiple Belongings

    DEFF Research Database (Denmark)

    Galal, Lise Paulsen; Sparre, Sara Cathrine Lei

    With the purpose of presenting DIMECCE key findings, we in this paper present different aspects, potentials and challenges related to the Middle Eastern Christians transnational connections and multiple belonging. We distinguish between individual transnational connections and practices......, such as family relations, churches as transnational – or global – institutions, and other organisations and associations established to support politically, socially or culturally connections and development in the country or region of origin....

  20. Hitchin's connection in metaplectic quantization

    DEFF Research Database (Denmark)

    Andersen, Jørgen Ellegaard; Gammelgaard, Niels Leth; Lauridsen, Magnus Roed

    2012-01-01

    We give a differential geometric construction of a connection, which we call the Hitchin connection, in the bundle of quantum Hilbert spaces arising from metaplectically corrected geometric quantization of a prequantizable, symplectic manifold, endowed with a rigid family of Kähler structures, all...... manifold in question. Furthermore, when we are in a setting similar to the moduli space, we give an explicit formula and show that this connection agrees with previous constructions....

  1. Interstate Connections - CEHC [ds619

    Data.gov (United States)

    California Department of Resources — The California Department of Transportation (Caltrans) and California Department of Fish and Game (CDFG) commissioned the California Essential Habitat Connectivity...

  2. Modeling interregional freight flow by distribution systems

    NARCIS (Netherlands)

    Davydenko, I.; Tavasszy, L.A.; Blois, C.J. de

    2013-01-01

    Distribution Centers with a warehousing function have an important influence on the flow of goods from production to consumption, generating substantial goods flow and vehicle movements. This paper extends the classical 4-step freight modeling framework with a logistics chain model, explicitly

  3. Interregional diversification of Ukraine's foreign trade

    Directory of Open Access Journals (Sweden)

    Viktor Chuzhykov

    2004-04-01

    Full Text Available This paper introduces a framework for studying regions in post-socialist countries, in particular Ukraine. The author identifies patterns in the gross state products (GSP, the concentration of foreign direct investments (FDI and diversification of foreign trade of Ukraine’s regions. Kyiv and the DonetskDnipropetrovsk-Zaporizhia industrial triangle have leading in foreign economic diversification over the past few years. Considering that production is not diversified and exports are primarily in ferrous metal products, the author identifies a degree of «regional susceptibility» resulting from the application of European and American frameworks, i.e. producer price index, consumer price index, openand RCA- (revealed comparative advantage export method, for studying regional foreign trade diversification in Ukraine. In concluding he proposes new methods to raise the quality of foreign trade forecasts of Ukraine’s regions.

  4. Whole-brain functional connectivity predicted by indirect structural connections

    DEFF Research Database (Denmark)

    Røge, Rasmus; Ambrosen, Karen Marie Sandø; Albers, Kristoffer Jon

    2017-01-01

    Modern functional and diffusion magnetic resonance imaging (fMRI and dMRI) provide data from which macro-scale networks of functional and structural whole brain connectivity can be estimated. Although networks derived from these two modalities describe different properties of the human brain......, they emerge from the same underlying brain organization, and functional communication is presumably mediated by structural connections. In this paper, we assess the structure-function relationship by evaluating how well functional connectivity can be predicted from structural graphs. Using high......-resolution whole brain networks generated with varying density, we contrast the performance of several non-parametric link predictors that measure structural communication flow. While functional connectivity is not well predicted directly by structural connections, we show that superior predictions can be achieved...

  5. Juno, The Cultural Connection

    Science.gov (United States)

    Clarke, Theodore

    2017-04-01

    After a 5 year journey and a billion miles cartwheeling through the vastness of space, the Juno spacecraft is in orbit about the planet Jupiter. With its suite of scientific instruments Juno scientists will catch a glimpse of the dawn of creation of our own solar system. Juno will address origins, asking for us all, Who am I? Where do I come from? But Juno is more than a space laboratory to study the planet Jupiter. Juno embodies the history of humankind's perception of the universe from Aristotle, Copernicus and Galileo, to the Juno spacecraft peering beneath the clouds of Jupiter. Juno embodies the literature of classical mythology and the timeless masterpieces of the Renaissance and Baroque periods in its very name. Juno carries to Jupiter small statuettes of the gods Jupiter and Juno and the scientist Galileo. Juno embodies cosmic visualization experiences through first ever movies of the moon occulting Earth (>2 million hits on YouTube) and the Galilean satellites orbiting about Jupiter (>1.8 million hits on You Tube). Juno embodies the stirring music of modern Greek composer Vangelis, the Orpheus of Juno, who provided the score for the movies of the moon occulting Earth and of the Galilean satellites orbiting Jupiter. Juno embodies down to Earth visualization experiences through trajectory models created of Juno's passage through the Earth-moon system and Juno's entire orbital mission at Jupiter. Juno is the embodiment of public engagement in its science in a fishbowl program. Indeed, because Juno is the embodiment of this remarkable union of science and technology, history and literature, music and art, and visualization and public engagement, Juno is truly an ambassador to the universe of a New Renaissance. In my paper, "Juno, the Cultural Connection," I will unveil a dimension of the Juno mission to the planet Jupiter that will appeal to a broad sector of the global public.

  6. Carl Sagan's Cosmic Connection

    Science.gov (United States)

    Sagan, Carl; Agel, Jerome

    2000-08-01

    Foreword Freeman Dyson; Personal reflections Ann Druyan; Preface; Part I. Cosmic Perspective: 1. A transitional animal; 2. The Unicorn of Cetus; 3. A message from earth; 4. A message to earth; 5. Experiments in utopias; 6. Chauvinism; 7. Space exploration as a human enterprise I. The scientific interest; 8. Space exploration as a human enterprise II. The public interest; 9. Space exploration as a human enterprise III. The historical interest; Part II. The Solar System: 10. On teaching the first grade; 11. 'The ancient and legendary Gods of old'; 12. The Venus detective story; 13. Venus is hell; 14. Science and 'intelligence'; 15. The moons of Barsoom; 16. The mountains of Mars I. Observations from earth; 17. The mountains of Mars II. Observations from space; 18. The canals of Mars; 19. The lost pictures of Mars; 20. The Ice Age and the cauldron; 21. Beginnings and ends of the Earth; 22. Terraforming the plants; 23. The exploration and utlization of the solar system; Part III. Beyond the Solar System: 24. Some of my best friends are dolphins; 25. 'Hello, central casting? Send me twenty extraterrestrials'; 26. The cosmic connection; 27. Extraterrestrial life: an idea whose time has come; 28. Has the Earth been visited?; 29. A search strategy for detecting extraterrestrial intelligence; 30. If we succeed 31. Cables, drums, and seashells; 32. The night freight to the stars; 33. Astroengineering; 34. Twenty questions: a classification of cosmic civilisations; 35. Galactic cultural exchanges; 36. A passage to elsewhere; 37. Starfolk I. A Fable; 38. Starfolk II. A future; 39. Starfolk III. The cosmic Cheshire cats; Epilog David Morrison; Index.

  7. Initial Validation for the Estimation of Resting-State fMRI Effective Connectivity by a Generalization of the Correlation Approach.

    Science.gov (United States)

    Xu, Nan; Spreng, R Nathan; Doerschuk, Peter C

    2017-01-01

    Resting-state functional MRI (rs-fMRI) is widely used to noninvasively study human brain networks. Network functional connectivity is often estimated by calculating the timeseries correlation between blood-oxygen-level dependent (BOLD) signal from different regions of interest (ROIs). However, standard correlation cannot characterize the direction of information flow between regions. In this paper, we introduce and test a new concept, prediction correlation, to estimate effective connectivity in functional brain networks from rs-fMRI. In this approach, the correlation between two BOLD signals is replaced by a correlation between one BOLD signal and a prediction of this signal via a causal system driven by another BOLD signal. Three validations are described: (1) Prediction correlation performed well on simulated data where the ground truth was known, and outperformed four other methods. (2) On simulated data designed to display the "common driver" problem, prediction correlation did not introduce false connections between non-interacting driven ROIs. (3) On experimental data, prediction correlation recovered the previously identified network organization of human brain. Prediction correlation scales well to work with hundreds of ROIs, enabling it to assess whole brain interregional connectivity at the single subject level. These results provide an initial validation that prediction correlation can capture the direction of information flow and estimate the duration of extended temporal delays in information flow between regions of interest ROIs based on BOLD signal. This approach not only maintains the high sensitivity to network connectivity provided by the correlation analysis, but also performs well in the estimation of causal information flow in the brain.

  8. Initial Validation for the Estimation of Resting-State fMRI Effective Connectivity by a Generalization of the Correlation Approach

    Directory of Open Access Journals (Sweden)

    Nan Xu

    2017-05-01

    Full Text Available Resting-state functional MRI (rs-fMRI is widely used to noninvasively study human brain networks. Network functional connectivity is often estimated by calculating the timeseries correlation between blood-oxygen-level dependent (BOLD signal from different regions of interest (ROIs. However, standard correlation cannot characterize the direction of information flow between regions. In this paper, we introduce and test a new concept, prediction correlation, to estimate effective connectivity in functional brain networks from rs-fMRI. In this approach, the correlation between two BOLD signals is replaced by a correlation between one BOLD signal and a prediction of this signal via a causal system driven by another BOLD signal. Three validations are described: (1 Prediction correlation performed well on simulated data where the ground truth was known, and outperformed four other methods. (2 On simulated data designed to display the “common driver” problem, prediction correlation did not introduce false connections between non-interacting driven ROIs. (3 On experimental data, prediction correlation recovered the previously identified network organization of human brain. Prediction correlation scales well to work with hundreds of ROIs, enabling it to assess whole brain interregional connectivity at the single subject level. These results provide an initial validation that prediction correlation can capture the direction of information flow and estimate the duration of extended temporal delays in information flow between regions of interest ROIs based on BOLD signal. This approach not only maintains the high sensitivity to network connectivity provided by the correlation analysis, but also performs well in the estimation of causal information flow in the brain.

  9. [Muscles and connective tissue: histology].

    Science.gov (United States)

    Delage, J-P

    2012-10-01

    Here, we give some comments about the DVD movies "Muscle Attitudes" from Endovivo productions, the movies up lighting some loss in the attention given to studies on the connective tissue, and especially them into muscles. The main characteristics of the different components in the intra-muscular connective tissue (perimysium, endomysium, epimysium) are shown here with special references to their ordered architecture and special references to their spatial distributions. This connective tissue is abundant into the muscles and is in continuity with the muscles in vicinity, with their tendons and their sheath, sticking the whole on skin. This connective tissue has also very abundant connections on the muscles fibres. It is then assumed that the connective tissue sticks every organs or cells of the locomotion system. Considering the elastic properties of the collagen fibres which are the most abundant component of connective tissue, it is possible to up light a panel of connective tissue associated functions such as the transmission of muscle contractions or the regulation of protein and energetic muscles metabolism. Copyright © 2012. Published by Elsevier SAS.

  10. Galois Connections for Flow Algebras

    DEFF Research Database (Denmark)

    Filipiuk, Piotr; Terepeta, Michal Tomasz; Nielson, Hanne Riis

    2011-01-01

    We generalise Galois connections from complete lattices to flow algebras. Flow algebras are algebraic structures that are less restrictive than idempotent semirings in that they replace distributivity with monotonicity and dispense with the annihilation property; therefore they are closer to the ...... using Galois connections such that correctness of the analyses is preserved. The approach is illustrated for a mutual exclusion algorithm....

  11. Connected Cruise Control : Final report

    NARCIS (Netherlands)

    van Arem, B.

    2013-01-01

    This report describes the final results of the Connected Cruise Control project. The
    Connected Cruise Control project was conducted from December 2009-April 2013 as a High Tech Automotive System Innovation project (HTASD09002), subsidized by
    Agentschap NL. The project was conducted by a

  12. Single-subject morphological brain networks: connectivity mapping, topological characterization and test-retest reliability.

    Science.gov (United States)

    Wang, Hao; Jin, Xiaoqing; Zhang, Ye; Wang, Jinhui

    2016-04-01

    Structural MRI has long been used to characterize local morphological features of the human brain. Coordination patterns of the local morphological features among regions, however, are not well understood. Here, we constructed individual-level morphological brain networks and systematically examined their topological organization and long-term test-retest reliability under different analytical schemes of spatial smoothing, brain parcellation, and network type. This study included 57 healthy participants and all participants completed two MRI scan sessions. Individual morphological brain networks were constructed by estimating interregional similarity in the distribution of regional gray matter volume in terms of the Kullback-Leibler divergence measure. Graph-based global and nodal network measures were then calculated, followed by the statistical comparison and intra-class correlation analysis. The morphological brain networks were highly reproducible between sessions with significantly larger similarities for interhemispheric connections linking bilaterally homotopic regions. Further graph-based analyses revealed that the morphological brain networks exhibited nonrandom topological organization of small-worldness, high parallel efficiency and modular architecture regardless of the analytical choices of spatial smoothing, brain parcellation and network type. Moreover, several paralimbic and association regions were consistently revealed to be potential hubs. Nonetheless, the three studied factors particularly spatial smoothing significantly affected quantitative characterization of morphological brain networks. Further examination of long-term reliability revealed that all the examined network topological properties showed fair to excellent reliability irrespective of the analytical strategies, but performing spatial smoothing significantly improved reliability. Interestingly, nodal centralities were positively correlated with their reliabilities, and nodal degree

  13. Relações sinérgicas e efeitos sobre a produção setorial no sistema inter-regional Paraná-Restante do Brasil

    Directory of Open Access Journals (Sweden)

    Rossana Lott Rodrigues

    2008-09-01

    Full Text Available O presente artigo tem como objetivo estimar e analisar o nível das interações sinérgicas e o transbordamento do efeito multiplicador da produção setorial entre o Paraná e o chamado "Restante do Brasil" (Brasil exceto Paraná, utilizando sistemas inter-regionais de insumo-produto estimados para os anos de 1995 e 2000. Os principais resultados mostraram que: a a dependência da produção do Paraná em relação ao fluxo de comércio com o Restante do Brasil se elevou de 25% em 1995 para 33% em 2000; b somente 1,36% da produção do Restante do Brasil dependeu do fluxo de insumos (bens e serviços entre este e o Paraná em 1995, reduzindo esta dependência para 0,56% em 2000; c a média do transbordamento do efeito multiplicador da produção dos setores da economia paranaense no sentido Restante do Brasil aumentou de 16% em 1995 para 20% em 2000, enquanto no sentido Restante do Brasil-Paraná, se manteve em 1%. Diante desses resultados, o poder público estadual, por meio de políticas que visem melhorar a infra-estrutura estadual e de políticas de estímulos setoriais, poderá colaborar, criando o aparato logístico e designando incentivos fiscais e/ou creditícios específicos que auxiliariam a iniciativa privada na implementação de suas atividades, de modo a tornar mais eficiente e vantajoso o comércio inter-regiões.The present article has as objective to calculate and to analyze the level of the synergic interactions and the overflow of the multiplying effect of the sectorial production between Parana and the Rest of Brazil (Brazil except Parana, using interregional systems of input-output estimated for the years of 1995 and 2000. The main results showed that: a the dependence of the production of Parana in relation to the flow of trade with the Rest of Brazil raised from 25% in 1995 to 33% in 2000; b only 1.36% of the production of the Rest of Brazil depended on the flow of input (goods and services between this and Parana in

  14. Framework for Connections on Facebook

    DEFF Research Database (Denmark)

    Sudzina, Frantisek

    There is a substantial amount of current information systems and marketing research focused on social networking sites, most frequently on Facebook. Often, these studies utilize available metadata on user on-line behavior, such as what links the users clicked on. In order to better understand...... behavior of Facebook users, it makes sense to investigate also whom the users connect to. It is possible to hypothesize that behavior of people, who connect only to relatives on Facebook, differs from behavior of people, who are connected only to their classmates. The paper offers a framework of Facebook...

  15. Optimizing connected component labeling algorithms

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Kesheng; Otoo, Ekow; Shoshani, Arie

    2005-01-16

    This paper presents two new strategies that can be used to greatly improve the speed of connected component labeling algorithms. To assign a label to a new object, most connected component labeling algorithms use a scanning step that examines some of its neighbors. The first strategy exploits the dependencies among them to reduce the number of neighbors examined. When considering 8-connected components in a 2D image, this can reduce the number of neighbors examined from four to one in many cases. The second strategy uses an array to store the equivalence information among the labels. This replaces the pointer based rooted trees used to store the same equivalence information. It reduces the memory required and also produces consecutive final labels. Using an array instead of the pointer based rooted trees speeds up the connected component labeling algorithms by a factor of 5 {approx} 100 in our tests on random binary images.

  16. Idaho: Library Automation and Connectivity.

    Science.gov (United States)

    Bolles, Charles

    1996-01-01

    Provides an overview of the development of cooperative library automation and connectivity in Idaho, including telecommunications capacity, library networks, the Internet, and the role of the state library. Information on six shared automation systems in Idaho is included. (LRW)

  17. Connected vehicles and your privacy.

    Science.gov (United States)

    2016-01-01

    Connected vehicles communicate wirelessly with other vehicles and our roads, : sharing important safety and mobility information and generating new data about : how, when, and where vehicles travel. The unprecedented level of data generated : will be...

  18. Connecting and Networking for Schools

    Science.gov (United States)

    Resources for connecting and networking for schools through e-newsletters, finding school IAQ Champions and other EPA school programs such as Asthma, Energy Star, Clean School Bus USA, School Flag, etc.

  19. Formal connections in deformation quantization

    DEFF Research Database (Denmark)

    Masulli, Paolo

    manifold. Gammelgaard gave an explicit formula for a class of star products in this setting. We review his construction, which is combinatorial and based on a certain family of graphs and extend it, to provide the graph formalism with the notions of composition and differentiation. We shall focus our...... attention on symplectic manifolds equipped with a family of star products, indexed by a parameter space. In this situation we can define a connection in the trivial bundle over the parameter space with fibres the formal smooth functions on the manifold, which relates the star products in the family...... and is called a formal connection. We study the question of classifying such formal connections. To each star product we can associate a certain cohomology class called the characteristic class. It turns out that a formal connection exists if and only if all the star products in the family have the same...

  20. Cybersecurity for Connected Diabetes Devices

    Science.gov (United States)

    Klonoff, David C.

    2015-01-01

    Diabetes devices are increasingly connected wirelessly to each other and to data-displaying reader devices. Threats to the accurate flow of information and commands may compromise the function of these devices and put their users at risk of health complications. Sound cybersecurity of connected diabetes devices is necessary to maintain confidentiality, integrity, and availability of the data and commands. Diabetes devices can be hacked by unauthorized agents and also by patients themselves to extract data that are not automatically provided by product software. Unauthorized access to connected diabetes devices has been simulated and could happen in reality. A cybersecurity standard designed specifically for connected diabetes devices will improve the safety of these products and increase confidence of users that the products will be secure. PMID:25883162

  1. Cybersecurity for Connected Diabetes Devices.

    Science.gov (United States)

    Klonoff, David C

    2015-04-16

    Diabetes devices are increasingly connected wirelessly to each other and to data-displaying reader devices. Threats to the accurate flow of information and commands may compromise the function of these devices and put their users at risk of health complications. Sound cybersecurity of connected diabetes devices is necessary to maintain confidentiality, integrity, and availability of the data and commands. Diabetes devices can be hacked by unauthorized agents and also by patients themselves to extract data that are not automatically provided by product software. Unauthorized access to connected diabetes devices has been simulated and could happen in reality. A cybersecurity standard designed specifically for connected diabetes devices will improve the safety of these products and increase confidence of users that the products will be secure. © 2015 Diabetes Technology Society.

  2. Connected domination stable graphs upon edge addition ...

    African Journals Online (AJOL)

    A set S of vertices in a graph G is a connected dominating set of G if S dominates G and the subgraph induced by S is connected. We study the graphs for which adding any edge does not change the connected domination number. Keywords: Connected domination, connected domination stable, edge addition ...

  3. Strongly 2-connected orientations of graphs

    DEFF Research Database (Denmark)

    Thomassen, Carsten

    2014-01-01

    We prove that a graph admits a strongly 2-connected orientation if and only if it is 4-edge-connected, and every vertex-deleted subgraph is 2-edge-connected. In particular, every 4-connected graph has such an orientation while no cubic 3-connected graph has such an orientation....

  4. Visualizing neuronal network connectivity with connectivity pattern tables

    Directory of Open Access Journals (Sweden)

    Eilen Nordlie

    2010-01-01

    Full Text Available Complex ideas are best conveyed through well-designed illustrations. Up to now, computational neuroscientists have mostly relied on box-and-arrow diagrams of even complex neuronal networks, often using ad hoc notations with conflicting use of symbols from paper to paper. This significantly impedes the communication of ideas in neuronal network modeling. We present here Connectivity Pattern Tables (CPTs as a clutter-free visualization of connectivity in large neuronal networks containing two-dimensional populations of neurons. CPTs can be generated automatically from the same script code used to create the actual network in the NEST simulator. Through aggregation, CPTs can be viewed at different levels, providing either full detail or summary information. We also provide the open source ConnPlotter tool as a means to create connectivity pattern tables.

  5. MedlinePlus Connect: Technical Information

    Science.gov (United States)

    ... page: https://medlineplus.gov/connect/technical.html MedlinePlus Connect: Technical Information To use the sharing features on ... Information Page Web Service Technical Information Page MedlinePlus Connect Implementation Options Web Application How does it work? ...

  6. MedlinePlus Connect: How it Works

    Science.gov (United States)

    ... page: https://medlineplus.gov/connect/howitworks.html MedlinePlus Connect: How it Works To use the sharing features ... to patients or providers within systems using MedlinePlus Connect? The Web application and Web service provide responses ...

  7. MedlinePlus Connect in Use

    Science.gov (United States)

    ... page: https://medlineplus.gov/connect/users.html MedlinePlus Connect in Use To use the sharing features on ... that have told us they are using MedlinePlus Connect . This is not a comprehensive list. If your ...

  8. MedlinePlus Connect: Email List

    Science.gov (United States)

    ... page: https://medlineplus.gov/connect/emaillist.html MedlinePlus Connect: Email List To use the sharing features on this page, please enable JavaScript. MedlinePlus Connect is a free service of the National Library ...

  9. MedlinePlus Connect: Web Application

    Science.gov (United States)

    ... page: https://medlineplus.gov/connect/application.html MedlinePlus Connect: Web Application To use the sharing features on this page, please enable JavaScript. MedlinePlus Connect is available as a Web application or Web ...

  10. Continuously Connected With Mobile IP

    Science.gov (United States)

    2002-01-01

    Cisco Systems developed Cisco Mobile Networks, making IP devices mobile. With this innovation, a Cisco router and its connected IP devices can roam across network boundaries and connection types. Because a mobile user is able to keep the same IP address while roaming, a live IP connection can be maintained without interruption. Glenn Research Center jointly tested the technology with Cisco, and is working to use it on low-earth-orbiting research craft. With Cisco's Mobile Networks functionality now available in Cisco IOS Software release 12.2(4)T, the commercial advantages and benefits are numerous. The technology can be applied to public safety, military/homeland security, emergency management services, railroad and shipping systems, and the automotive industry. It will allow ambulances, police, firemen, and the U.S. Coast Guard to stay connected to their networks while on the move. In the wireless battlefield, the technology will provide rapid infrastructure deployment for U.S. national defense. Airline, train, and cruise passengers utilizing Cisco Mobile Networks can fly all around the world with a continuous Internet connection. Cisco IOS(R) Software is a registered trademark of Cisco Systems.

  11. Review on Cold-Formed Steel Connections

    Science.gov (United States)

    Tan, Cher Siang; Mohammad, Shahrin; Md Tahir, Mahmood; Shek, Poi Ngian

    2014-01-01

    The concept of cold-formed light steel framing construction has been widespread after understanding its structural characteristics with massive research works over the years. Connection serves as one of the important elements for light steel framing in order to achieve its structural stability. Compared to hot-rolled steel sections, cold-formed steel connections perform dissimilarity due to the thin-walled behaviour. This paper aims to review current researches on cold-formed steel connections, particularly for screw connections, storage rack connections, welded connections, and bolted connections. The performance of these connections in the design of cold-formed steel structures is discussed. PMID:24688448

  12. Review on cold-formed steel connections.

    Science.gov (United States)

    Lee, Yeong Huei; Tan, Cher Siang; Mohammad, Shahrin; Tahir, Mahmood Md; Shek, Poi Ngian

    2014-01-01

    The concept of cold-formed light steel framing construction has been widespread after understanding its structural characteristics with massive research works over the years. Connection serves as one of the important elements for light steel framing in order to achieve its structural stability. Compared to hot-rolled steel sections, cold-formed steel connections perform dissimilarity due to the thin-walled behaviour. This paper aims to review current researches on cold-formed steel connections, particularly for screw connections, storage rack connections, welded connections, and bolted connections. The performance of these connections in the design of cold-formed steel structures is discussed.

  13. Review on Cold-Formed Steel Connections

    Directory of Open Access Journals (Sweden)

    Yeong Huei Lee

    2014-01-01

    Full Text Available The concept of cold-formed light steel framing construction has been widespread after understanding its structural characteristics with massive research works over the years. Connection serves as one of the important elements for light steel framing in order to achieve its structural stability. Compared to hot-rolled steel sections, cold-formed steel connections perform dissimilarity due to the thin-walled behaviour. This paper aims to review current researches on cold-formed steel connections, particularly for screw connections, storage rack connections, welded connections, and bolted connections. The performance of these connections in the design of cold-formed steel structures is discussed.

  14. New rituals for public connection

    DEFF Research Database (Denmark)

    Swart, Joëlle; Peters, Chris; Broersma, Marcel

    2017-01-01

    This chapter explores how digitalization facilitates new patterns of using news to connect to larger social, cultural, civic and political frameworks. Employing in-depth interviews and Q-methodology with Dutch news users of mixed age, gender and educational level in three regions, it finds...... that news still provides a major frame of reference to public issues in users’ everyday communications. Rather than a complete ‘de-ritualization’ of news practices, wherein no common trajectories for connecting to public life can be discerned anymore, we argue digitalization facilitates a ‘re......-ritualization’ of public connection in which traditional and new media logics interact. While the news still facilitates community, self-presentation and security, the forms of public engagement people employ to satisfy these needs are increasingly centered around individuals, inextricably embedded in other activities...

  15. Parcellating connectivity in spatial maps.

    Science.gov (United States)

    Baldassano, Christopher; Beck, Diane M; Fei-Fei, Li

    2015-01-01

    A common goal in biological sciences is to model a complex web of connections using a small number of interacting units. We present a general approach for dividing up elements in a spatial map based on their connectivity properties, allowing for the discovery of local regions underlying large-scale connectivity matrices. Our method is specifically designed to respect spatial layout and identify locally-connected clusters, corresponding to plausible coherent units such as strings of adjacent DNA base pairs, subregions of the brain, animal communities, or geographic ecosystems. Instead of using approximate greedy clustering, our nonparametric Bayesian model infers a precise parcellation using collapsed Gibbs sampling. We utilize an infinite clustering prior that intrinsically incorporates spatial constraints, allowing the model to search directly in the space of spatially-coherent parcellations. After showing results on synthetic datasets, we apply our method to both functional and structural connectivity data from the human brain. We find that our parcellation is substantially more effective than previous approaches at summarizing the brain's connectivity structure using a small number of clusters, produces better generalization to individual subject data, and reveals functional parcels related to known retinotopic maps in visual cortex. Additionally, we demonstrate the generality of our method by applying the same model to human migration data within the United States. This analysis reveals that migration behavior is generally influenced by state borders, but also identifies regional communities which cut across state lines. Our parcellation approach has a wide range of potential applications in understanding the spatial structure of complex biological networks.

  16. Parcellating connectivity in spatial maps

    Directory of Open Access Journals (Sweden)

    Christopher Baldassano

    2015-02-01

    Full Text Available A common goal in biological sciences is to model a complex web of connections using a small number of interacting units. We present a general approach for dividing up elements in a spatial map based on their connectivity properties, allowing for the discovery of local regions underlying large-scale connectivity matrices. Our method is specifically designed to respect spatial layout and identify locally-connected clusters, corresponding to plausible coherent units such as strings of adjacent DNA base pairs, subregions of the brain, animal communities, or geographic ecosystems. Instead of using approximate greedy clustering, our nonparametric Bayesian model infers a precise parcellation using collapsed Gibbs sampling. We utilize an infinite clustering prior that intrinsically incorporates spatial constraints, allowing the model to search directly in the space of spatially-coherent parcellations. After showing results on synthetic datasets, we apply our method to both functional and structural connectivity data from the human brain. We find that our parcellation is substantially more effective than previous approaches at summarizing the brain’s connectivity structure using a small number of clusters, produces better generalization to individual subject data, and reveals functional parcels related to known retinotopic maps in visual cortex. Additionally, we demonstrate the generality of our method by applying the same model to human migration data within the United States. This analysis reveals that migration behavior is generally influenced by state borders, but also identifies regional communities which cut across state lines. Our parcellation approach has a wide range of potential applications in understanding the spatial structure of complex biological networks.

  17. Ekspert i undervisning - IRIS Connect

    DEFF Research Database (Denmark)

    Wullum, Annemette Heine; Eriksen, Frits Hedegaard

    2014-01-01

    Ekspert i undervisning – IRIS Connect Credoet bag de seneste års mange læreruddannelsesreformer har været, at flere og dybere kundskaber vil styrke de studerendes forudsætninger for at løse opgaverne i pædagogisk praksis. Et forhold, som bliver overset i forbindelse med uddannelsesreformerne, er...... praksis, og hvad ”effektiv” undervisning er. Hovedantagelserne bag projektet er, at de studerendes personbundne kundskaber kan synliggøres, at deres lægmandsopfattelser af, hvad ”effektiv” undervisning er, kan udfordres gennem analyser og drøftelser, og at brugen af IRIS Connects dataindsamlings- og...

  18. Generalized connected domination in graphs

    Directory of Open Access Journals (Sweden)

    M. Kouider

    2006-01-01

    Full Text Available As a generalization of connected domination in a graph G we consider domination by sets having at most k components. The order γ c k (G of such a smallest set we relate to γ c (G, the order of a smallest connected dominating set. For a tree T we give bounds on γ c k (T in terms of minimum valency and diameter. For trees the inequality γ c k (T≤ n-k-1 is known to hold, we determine the class of trees, for which equality holds.

  19. Religion and Ethnicity: Theoretical Connections

    Directory of Open Access Journals (Sweden)

    Rebecca Y. Kim

    2011-07-01

    Full Text Available The religion literature in Sociology remains largely disconnected from the ethnicity and immigration literature despite enduring connections between religion and ethnicity. This review helps to close this gap. It shows how the dominant theories in each discipline follow a similar trajectory and examines how exploring the theoretical connections between religion and ethnicity can advance our understanding of each social phenomenon. In particular, it can illuminate why America remains so religious as well as why America’s religious congregations continue to be so divided along ethnic and racial lines.

  20. Developing a Connective Feminine Discourse

    DEFF Research Database (Denmark)

    Rahbek, Ulla

    2015-01-01

    This paper discusses the work of the Australian writer and historian Drusilla Modjeska through a focus on the intersections between women‟s lives, love and art, which constitute the central triptych of Modjeska‟s writing. It argues that Modjeska's oeuvre unfolds a connective feminine discourse...... through a development of what the paper calls hinging tropes, discursive connectors that join life, love and art, such as weaving, folding and talking. That connective feminine discourse is indeed central to Modjeska‟s personal and sometimes idiosyncratic feminism...

  1. The effect of inter-annual variability of consumption, production, trade and climate on crop-related green and blue water footprints and inter-regional virtual water trade: A study for China (1978e2008)

    NARCIS (Netherlands)

    Zhuo, L.; Mekonnen, Mesfin; Hoekstra, Arjen Ysbert

    2016-01-01

    Previous studies into the relation between human consumption and indirect water resources use have unveiled the remote connections in virtual water (VW) trade networks, which show how communities externalize their water footprint (WF) to places far beyond their own region, but little has been done

  2. Connected Firms and Investor Myopia

    NARCIS (Netherlands)

    Ginglinger, Edith; Hébert, Camille; Renneboog, Luc

    2017-01-01

    Conglomerates, multinational corporations and business groups are non-exclusive forms of complex firms. Often organized as corporate networks, complex firms control a myriad of firms connected through ownership links. We investigate whether parent-subsidiary links within corporate networks enhance

  3. Connecting device for air ducts

    Energy Technology Data Exchange (ETDEWEB)

    Kippenberger, G.

    1979-11-29

    The connecting device for air ducts described consists of matched coupling elements of great tensile strength in the form of eyes and cords, which are fitted on the front of the air duct sections. There is a sleeve apron on one side which projects into the other section of air duct.

  4. Mundtlig eksamen via Adobe Connect

    DEFF Research Database (Denmark)

    Kjær, Christopher

    2011-01-01

    I løbet af de sidste tre år har der på Syddansk Universitet (SDU) været afholdt mere end 20 mundtlige kandidatforsvar samt andre mundtlige eksaminationer via webkonferencesystemet Adobe Connect. Formålet med denne artikel er at videregive de praktiske erfaringer fra gennemførelsen af disse...... eksaminationer samt at opstille nogle hensigtsmæssige retningslinjer for dem, der ønsker at give sig i kast med mundtlig eksamination via Adobe Connect. Der indledes derfor med en generel præsentation af Adobe Connect samt de elementer ved systemet, som oftest anvendes i forbindelse med mundtlig eksamination....... Heref ter præsenteres de typiske årsager til, at Adobe Connect anvendes til eksamination. I forlængelse heraf gennemgås nogle scenarier for afholdelse af mundtlig eksamination i systemet. Nogle af disse scenarier suppleres med beskrivelser af deltagernes oplevelser og erfaringer med gennemførelsen af...

  5. Indicators of malicious SSL connections

    NARCIS (Netherlands)

    Bortolameotti, R.; Peter, A.; Everts, M.H.; Bolzoni, D.

    2015-01-01

    Internet applications use SSL to provide data confidentiality to communicating entities. The use of encryption in SSL makes it impossible to distinguish between benign and malicious connections as the content cannot be inspected. Therefore, we propose and evaluate a set of indicators for malicious

  6. Gigabit Wireless for Network Connectivity

    Science.gov (United States)

    Schoedel, Eric

    2009-01-01

    Uninterrupted, high-bandwidth network connectivity is crucial for higher education. Colleges and universities increasingly adopt gigabit wireless solutions because of their fiber-equivalent performance, quick implementation, and significant return on investment. For just those reasons, Rush University Medical Center switched from free space optics…

  7. The Imagery-Creativity Connection.

    Science.gov (United States)

    Daniels-McGhee, Susan; Davis, Gary A.

    1994-01-01

    This paper reviews historical highlights of the imagery-creativity connection, including early and contemporary accounts, along with notable examples of imagery in the creative process. It also looks at cross-modal imagery (synesthesia), a model of image-based creativity and the creative process, and implications for strengthening creativity by…

  8. Indicators of Malicious SSL Connections

    NARCIS (Netherlands)

    Bortolameotti, Riccardo; Peter, Andreas; Everts, Maarten Hinderik; Bolzoni, D.

    Internet applications use SSL to provide data confidential- ity to communicating entities. The use of encryption in SSL makes it impossible to distinguish between benign and malicious connections as the content cannot be inspected. Therefore, we propose and evaluate a set of indicators for malicious

  9. Elementary Algebra Connections to Precalculus

    Science.gov (United States)

    Lopez-Boada, Roberto; Daire, Sandra Arguelles

    2013-01-01

    This article examines the attitudes of some precalculus students to solve trigonometric and logarithmic equations and systems using the concepts of elementary algebra. With the goal of enticing the students to search for and use connections among mathematical topics, they are asked to solve equations or systems specifically designed to allow…

  10. Art and the Cosmic Connection

    Science.gov (United States)

    Cobb, Whitney H.; Aiello, Monica Petty; Macdonald, Reeves; Asplund, Shari

    2014-01-01

    The interdisciplinary unit described in this article utilizes "Art and the Cosmic Connection," a free program conceived of by artists Monica and Tyler Aiello and developed by the artists, scientists, and educators through NASA's Discovery and New Frontiers Programs, to inspire learners to explore mysterious worlds in our solar…

  11. Quality Connection: Going the Distance

    Science.gov (United States)

    Jenney, Timothy R.; Roupas, Eva K.

    2003-01-01

    In 1999, Virginia Beach City Public Schools launched a completely new distance learning (DL) initiative, Quality Connection. Since that time, through perseverance and creative thinking, the program has become a model of technology as well as a highly successful method of delivering services to a wide variety of stakeholders. Not only do students…

  12. Connections for small vertex models

    Indian Academy of Sciences (India)

    Home; Journals; Proceedings – Mathematical Sciences; Volume 110; Issue 1. Connections for Small Vertex Models. R Srinivasan. Volume 110 Issue 1 February 2000 pp 35-53 ... Author Affiliations. R Srinivasan1. Mehta Research Institute of Mathematics and Mathematical Physics, Allahabad 211 019, India ...

  13. Privacy and the Connected Society

    DEFF Research Database (Denmark)

    Sørensen, Lene Tolstrup; Khajuria, Samant; Skouby, Knud Erik

    The Vision of the 5G enabled connected society is highly based on the evolution and implementation of Internet of Things. This involves, amongst others, a significant raise in devices, sensors and communication in pervasive interconnections as well as cooperation amongst devices and entities acro...

  14. Connecting leadership and learning: Do versatile learners make connective leaders?

    OpenAIRE

    Robinson, Jill L.

    2016-01-01

    Recent failures in leadership, suggest that creating better-quality leadership development programs is critical. In moving from theory to practice, this paper examined the relationship between learning style and leadership style which may enable us to move away from one-size-fits-all leadership development programs. Utilizing Kolb’s Experiential Learning Model and Connective Leadership theory, approximately 3600 college students were analyzed to discover whether versatility in learning styles...

  15. Connecting Leadership and Learning: Do Versatile Learners make Connective Leaders?

    OpenAIRE

    Jill L. Robinson

    2016-01-01

    Abstract Recent failures in leadership, suggest that creating better-quality leadership development programs is critical. In moving from theory to practice, this paper examined the relationship between learning style and leadership style which may enable us to move away from one-size-fits-all leadership development programs. Utilizing Kolb’s Experiential Learning Model and Connective Leadership theory, approximately 3600 college students were analyzed to discover whether versatility in le...

  16. Connected Worlds: Connecting the public with complex environmental systems

    Science.gov (United States)

    Uzzo, S. M.; Chen, R. S.; Downs, R. R.

    2016-12-01

    Among the most important concepts in environmental science learning is the structure and dynamics of coupled human and natural systems (CHANS). But the fundamental epistemology for understanding CHANS requires systems thinking, interdisciplinarity, and complexity. Although the Next Generation Science Standards mandate connecting ideas across disciplines and systems, traditional approaches to education do not provide more than superficial understanding of this concept. Informal science learning institutions have a key role in bridging gaps between the reductive nature of classroom learning and contemporary data-driven science. The New York Hall of Science, in partnership with Design I/O and Columbia University's Center for International Earth Science Information Network, has developed an approach to immerse visitors in complex human nature interactions and provide opportunities for those of all ages to elicit and notice environmental consequences of their actions. Connected Worlds is a nearly 1,000 m2 immersive, playful environment in which students learn about complexity and interconnectedness in ecosystems and how ecosystems might respond to human intervention. It engages students through direct interactions with fanciful flora and fauna within and among six biomes: desert, rainforest, grassland, mountain valley, reservoir, and wetlands, which are interconnected through stocks and flows of water. Through gestures and the manipulation of a dynamic water system, Connected Worlds enables students, teachers, and parents to experience how the ecosystems of planet Earth are connected and to observe relationships between the behavior of Earth's inhabitants and our shared world. It is also a cyberlearning platform to study how visitors notice and scaffold their understanding of complex environmental processes and the responses of these processes to human intervention, to help inform the improvement of education practices in complex environmental science.

  17. UNBIASED ESTIMATORS OF SPECIFIC CONNECTIVITY

    Directory of Open Access Journals (Sweden)

    Jean-Paul Jernot

    2011-05-01

    Full Text Available This paper deals with the estimation of the specific connectivity of a stationary random set in IRd. It turns out that the "natural" estimator is only asymptotically unbiased. The example of a boolean model of hypercubes illustrates the amplitude of the bias produced when the measurement field is relatively small with respect to the range of the random set. For that reason unbiased estimators are desired. Such an estimator can be found in the literature in the case where the measurement field is a right parallelotope. In this paper, this estimator is extended to apply to measurement fields of various shapes, and to possess a smaller variance. Finally an example from quantitative metallography (specific connectivity of a population of sintered bronze particles is given.

  18. Content, Context & Connectivity Persuasive Interplay

    DEFF Research Database (Denmark)

    Sørensen, Christian Grund

    2013-01-01

    The aim of this paper is to discuss the relationship between content, context and connectivity and suggesting a model of Dynamic Interplay. This is done in relation to a specific learning environment concerning cultural mediation, in casu the Kaj Munk Case of the EuroPLOT-project (an EU-supported......The aim of this paper is to discuss the relationship between content, context and connectivity and suggesting a model of Dynamic Interplay. This is done in relation to a specific learning environment concerning cultural mediation, in casu the Kaj Munk Case of the EuroPLOT-project (an EU......-supported research project under EACEA). In the development of this project several categories of content have been implemented in technology enhanced learning tools. These have been designed to support learning in different contexts and eventually the role of the connectivity of these learning objects and tools...... is discussed. Focus is here on The Kaj Munk Study Edition, The Conceptual Pond, Immersive Layers Design, and Generative Learning Objects (GLOs) which are applications affiliated with the Munk case. This paper explores the persuasive potential of the interplay between the different applications for the benefit...

  19. 78 FR 28626 - Te Connectivity, Industrial Division, Middletown, Pennsylvania; Te Connectivity, Corporate Shared...

    Science.gov (United States)

    2013-05-15

    ..., Corporate Shared Services Group 100 & 200 Amp Drive, Harrisburg, Pennsylvania; Te Connectivity Corporate Shared Services Group, 3700 Reidsville Road, Winston-Salem, North Carolina; Te Connectivity, Corporate Shared Services Group, 1187 Park Place, Shakopee, Minnesota; Te Connectivity, Corporate Shared Services...

  20. Mathematical connections a capstone course

    CERN Document Server

    Conway, John B

    2010-01-01

    This book illustrates connections between various courses taken by undergraduate mathematics majors. As such it can be used as a text for a capstone course. The chapters are essentially independent, and the instructor can choose the topics that will form the course and thus tailor the syllabus to suit the backgrounds and abilities of the students. At the end of such a course the graduating seniors should glimpse mathematics not as a series of independent courses but as something more like an integrated body of knowledge. The book has numerous exercises and examples so that the student has many

  1. Study of rectenna array connection

    Energy Technology Data Exchange (ETDEWEB)

    Miura, T.; Shinohara, N.; Matsumoto, H. [Kyoto Univ., Uji (Japan). Engineering Research Inst.

    1997-11-01

    A study was conducted in which a new rectenna working at 2.45 GHz microwave was developed for ground-to-ground microwave power transmission. The new rectenna consists of an antenna section and a rectifying section. The new design is simple and therefore more accurate than a micro-strip type patch antenna. The efficiency of conversion of microwave power to direct current depends on the mutual dependence of antenna elements and circuit conditions of rectifying sections. A series of experiments were conducted to analyze the rectenna characteristics and a method for efficiently connecting rectenna arrays was proposed. 3 refs., 2 tabs., 15 figs.

  2. Recreating Intimacy With Connected Consumers

    Directory of Open Access Journals (Sweden)

    Stephen Andrew

    2017-11-01

    Full Text Available In the good old times shop manager knew their customers personally and were able to tailor offerings to their needs and desires. But how can we create meaningful moments for connected consumers in global markets? Yasmeen Ahmad explains how in digital times data fill in. Smart algorithms help generate insights and enable real time action to provide the right product and service to the right customer at the right time. Companies that don’t want to be left behind a digital elite need to remain close to their customers across multiple digital touchpoints. Being capable of reading, interpreting and acting upon consumers` traces is a prerequisite.

  3. Connected and autonomous vehicles 2040 vision.

    Science.gov (United States)

    2014-07-01

    The Pennsylvania Department of Transportation (PennDOT) commissioned a one-year project, Connected and Autonomous : Vehicles 2040 Vision, with researchers at Carnegie Mellon University (CMU) to assess the implications of connected and : autonomous ve...

  4. Connecting Related Rates and Differential Equations

    Science.gov (United States)

    Brandt, Keith

    2012-01-01

    This article points out a simple connection between related rates and differential equations. The connection can be used for in-class examples or homework exercises, and it is accessible to students who are familiar with separation of variables.

  5. DS-Connect: The Down Syndrome Registry

    Science.gov (United States)

    ... Read the Research Review Policy Contact Us DS-Connect® is a powerful resource where people with Down syndrome and their families can: Connect with researchers and health care providers. Express interest ...

  6. Endophenotypes in a Dynamically Connected Brain

    NARCIS (Netherlands)

    Smit, D.J.A.; Boersma, M.; van Beijsterveldt, C.E.M.; Posthuma, D.; Boomsma, D.I.; Stam, C.J.; de Geus, E.J.C.

    2010-01-01

    We examined the longitudinal genetic architecture of three parameters of functional brain connectivity. One parameter described overall connectivity (synchronization likelihood, SL). The two others were derived from graph theory and described local (clustering coefficient, CC) and global (average

  7. Ecological connectivity networks in rapidly expanding cities

    OpenAIRE

    Nor, A.N.M.; R. Corstanje; Harris, J.A.; Grafius, D.R.; Siriwardena, G.M.

    2017-01-01

    Urban expansion increases fragmentation of the landscape. In effect, fragmentation decreases connectivity, causes green space loss and impacts upon the ecology and function of green space. Restoration of the functionality of green space often requires restoring the ecological connectivity of this green space within the city matrix. However, identifying ecological corridors that integrate different structural and functional connectivity of green space remains vague. Assessing connectivity for ...

  8. Drill pipe threaded nipple connection design development

    OpenAIRE

    Saruev, Aleksey Lvovich; Saruev, Lev Alekseevich; Vasenin, S. S.

    2015-01-01

    The paper presents the analysis of the behavior of the drill pipe nipple connection under the additional load generated by power pulses. The strain wave propagation through the nipple thread connection of drill pipes to the bottomhole is studied in this paper. The improved design of the nipple thread connection is suggested using the obtained experimental and theoretical data. The suggested connection design allows not only the efficient transmission of strain wave energy to a drill bit but a...

  9. Connectivity editing for quadrilateral meshes

    KAUST Repository

    Peng, Chihan

    2011-12-01

    We propose new connectivity editing operations for quadrilateral meshes with the unique ability to explicitly control the location, orientation, type, and number of the irregular vertices (valence not equal to four) in the mesh while preserving sharp edges. We provide theoretical analysis on what editing operations are possible and impossible and introduce three fundamental operations to move and re-orient a pair of irregular vertices. We argue that our editing operations are fundamental, because they only change the quad mesh in the smallest possible region and involve the fewest irregular vertices (i.e., two). The irregular vertex movement operations are supplemented by operations for the splitting, merging, canceling, and aligning of irregular vertices. We explain how the proposed high-level operations are realized through graph-level editing operations such as quad collapses, edge flips, and edge splits. The utility of these mesh editing operations are demonstrated by improving the connectivity of quad meshes generated from state-of-art quadrangulation techniques.

  10. Astrophysicists' conversational connections on Twitter.

    Science.gov (United States)

    Holmberg, Kim; Bowman, Timothy D; Haustein, Stefanie; Peters, Isabella

    2014-01-01

    Because Twitter and other social media are increasingly used for analyses based on altmetrics, this research sought to understand what contexts, affordance use, and social activities influence the tweeting behavior of astrophysicists. Thus, the presented study has been guided by three research questions that consider the influence of astrophysicists' activities (i.e., publishing and tweeting frequency) and of their tweet construction and affordance use (i.e. use of hashtags, language, and emotions) on the conversational connections they have on Twitter. We found that astrophysicists communicate with a variety of user types (e.g. colleagues, science communicators, other researchers, and educators) and that in the ego networks of the astrophysicists clear groups consisting of users with different professional roles can be distinguished. Interestingly, the analysis of noun phrases and hashtags showed that when the astrophysicists address the different groups of very different professional composition they use very similar terminology, but that they do not talk to each other (i.e. mentioning other user names in tweets). The results also showed that in those areas of the ego networks that tweeted more the sentiment of the tweets tended to be closer to neutral, connecting frequent tweeting with information sharing activities rather than conversations or expressing opinions.

  11. Astrophysicists' conversational connections on Twitter.

    Directory of Open Access Journals (Sweden)

    Kim Holmberg

    Full Text Available Because Twitter and other social media are increasingly used for analyses based on altmetrics, this research sought to understand what contexts, affordance use, and social activities influence the tweeting behavior of astrophysicists. Thus, the presented study has been guided by three research questions that consider the influence of astrophysicists' activities (i.e., publishing and tweeting frequency and of their tweet construction and affordance use (i.e. use of hashtags, language, and emotions on the conversational connections they have on Twitter. We found that astrophysicists communicate with a variety of user types (e.g. colleagues, science communicators, other researchers, and educators and that in the ego networks of the astrophysicists clear groups consisting of users with different professional roles can be distinguished. Interestingly, the analysis of noun phrases and hashtags showed that when the astrophysicists address the different groups of very different professional composition they use very similar terminology, but that they do not talk to each other (i.e. mentioning other user names in tweets. The results also showed that in those areas of the ego networks that tweeted more the sentiment of the tweets tended to be closer to neutral, connecting frequent tweeting with information sharing activities rather than conversations or expressing opinions.

  12. Astrophysicists’ Conversational Connections on Twitter

    Science.gov (United States)

    Holmberg, Kim; Bowman, Timothy D.; Haustein, Stefanie; Peters, Isabella

    2014-01-01

    Because Twitter and other social media are increasingly used for analyses based on altmetrics, this research sought to understand what contexts, affordance use, and social activities influence the tweeting behavior of astrophysicists. Thus, the presented study has been guided by three research questions that consider the influence of astrophysicists’ activities (i.e., publishing and tweeting frequency) and of their tweet construction and affordance use (i.e. use of hashtags, language, and emotions) on the conversational connections they have on Twitter. We found that astrophysicists communicate with a variety of user types (e.g. colleagues, science communicators, other researchers, and educators) and that in the ego networks of the astrophysicists clear groups consisting of users with different professional roles can be distinguished. Interestingly, the analysis of noun phrases and hashtags showed that when the astrophysicists address the different groups of very different professional composition they use very similar terminology, but that they do not talk to each other (i.e. mentioning other user names in tweets). The results also showed that in those areas of the ego networks that tweeted more the sentiment of the tweets tended to be closer to neutral, connecting frequent tweeting with information sharing activities rather than conversations or expressing opinions. PMID:25153196

  13. Connectivity editing for quadrilateral meshes

    KAUST Repository

    Peng, Chihan

    2011-12-12

    We propose new connectivity editing operations for quadrilateral meshes with the unique ability to explicitly control the location, orientation, type, and number of the irregular vertices (valence not equal to four) in the mesh while preserving sharp edges. We provide theoretical analysis on what editing operations are possible and impossible and introduce three fundamental operations to move and re-orient a pair of irregular vertices. We argue that our editing operations are fundamental, because they only change the quad mesh in the smallest possible region and involve the fewest irregular vertices (i.e., two). The irregular vertex movement operations are supplemented by operations for the splitting, merging, canceling, and aligning of irregular vertices. We explain how the proposed highlevel operations are realized through graph-level editing operations such as quad collapses, edge flips, and edge splits. The utility of these mesh editing operations are demonstrated by improving the connectivity of quad meshes generated from state-of-art quadrangulation techniques. © 2011 ACM.

  14. 78 FR 48622 - Connect America Fund

    Science.gov (United States)

    2013-08-09

    ... COMMISSION 47 CFR Part 54 Connect America Fund AGENCY: Federal Communications Commission. ACTION: Final rule... Connect America funds are used to subsidize the overbuilding of their existing networks. B. Final... revising paragraphs (b)(3) and (c)(4) to read as follows: Sec. 54.312 Connect America Fund in Price Cap...

  15. 78 FR 32991 - Connect America Fund

    Science.gov (United States)

    2013-06-03

    ... COMMISSION 47 CFR Part 54 Connect America Fund AGENCY: Federal Communications Commission. ACTION: Final rule... challenge process that will be used to finalize the list of areas that will be eligible for Connect America... known as the Connect America Fund through ``a combination of competitive bidding and a new forward...

  16. 77 FR 76435 - Connect America Fund

    Science.gov (United States)

    2012-12-28

    ...; FCC 12-138] Connect America Fund AGENCY: Federal Communications Commission. ACTION: Proposed rule... Proposed Rulemaking on potential modifications to the rules governing Connect America Phase I incremental... available to as many unserved locations as possible in those areas. In Connect America Phase I, the...

  17. 77 FR 52616 - Connect America Fund

    Science.gov (United States)

    2012-08-30

    .... 01-92, 96-45; WT Docket No. 10-208; DA 12-1155] Connect America Fund AGENCY: Federal Communications... certain rules relating to Phase I of the Connect America Fund. Commission staff have received informal inquiries from price cap companies on certain implementation aspects of the rules governing Connect America...

  18. 78 FR 44893 - Connect America Fund

    Science.gov (United States)

    2013-07-25

    ... COMMISSION 47 CFR Part 54 Connect America Fund AGENCY: Federal Communications Commission. ACTION: Final rule... information collection associated with the Commission's Universal Service--Connect America Fund, Report and... information collection requirements. DATES: The rules associated with the Connect America Phase II challenge...

  19. Airport industry connectivity report: 2004-2014

    NARCIS (Netherlands)

    Burghouwt, G.; Lieshout, R.

    2014-01-01

    Airport connectivity is an increasingly discussed topic in European policy circles. With good reason. Connectivity is closely connected with productivity, economic growth and international trade. And with the centre of global economic activity shifting eastward, it is essential that Europe remains

  20. MedlinePlus Connect: Web Service

    Science.gov (United States)

    ... https://medlineplus.gov/connect/service.html MedlinePlus Connect: Web Service To use the sharing features on this page, ... if you implement MedlinePlus Connect by contacting us . Web Service Overview The parameters for the Web service requests ...

  1. The Stellar-Solar Connection

    Science.gov (United States)

    Ayres, T. R.

    2004-05-01

    Many solar-stellar astronomers believe that the solar-stellar connection primarily is a one-way street: the exquisitely detailed studies of the solar surface, interior, and heliosphere strongly mold our views of the distant, unresolved stars. Perhaps many solar physicists have gone so far as to adopt the myopic view that stellar astronomy, by and large, is merely sponging up the fabulous insights from ever deeper examinations of our local star, but the ``dark side'' is not really capable of returning the favor. What could we possibly learn from the stars, that we don't already know from much better observations of the Sun? In my Introduction to this Topical Session, I will discuss two broad issues: (1) the present divergence between solar and stellar physics (driven by the different goals and tools of the two disciplines); and (2) the diversity of stars in the H-R diagram, to help inform our understanding of solar processes. Today, there are observations of stars that greatly exceed the quality of analogous solar measurements: e.g., HST/STIS UV echelle spectra of Alpha Cen A; Chandra transmission grating spectra of solar-type stars; and only recently have we obtained a definitive understanding of the Sun's soft X-ray luminosity in the key ROSAT/PSPC band. The lack of equivalent solar observations hinders practical applications of the solar-stellar connection. On the more informative side, the evolutionary paths of other stars can be quite different from the Sun's, with potentially dramatic influences on phenomena such as magnetic activity. Equally important, examples of Sun-like stars can be found at all stages of evolution, from proplyds to red giants, in the volume of nearby space out to 500 pc. In short, the solar-stellar connection need not be a one-way street, but rather a powerful tool to explore solar processes within the broader context of stars and stellar evolution. This work was supported by NASA grant NAG5-13058.

  2. Making connections: reflection, feedback and support

    Directory of Open Access Journals (Sweden)

    Jane Seale

    2007-12-01

    Full Text Available Hansell (1974 conceptualized seven different connections or attachments that we have to the world in which we live: attachments that consist of connections to other people, to a social role as well as to a system of meaning. For many, learning is at the heart of the process of making connections, particularly meaningful connections (Horton, 2000. If this is true, then it leads us to consider the extent to which educators, the systems they work in and the tools they use have a role to play in helping learners make those meaningful connections. For example, Scherer (2002, p. 5 suggests that educational systems have a responsibility to:

  3. Behavior of concentrically loaded CFT braces connections

    Directory of Open Access Journals (Sweden)

    Maha M. Hassan

    2014-03-01

    Full Text Available Concrete filled tubes (CFTs composite columns have many economical and esthetic advantages, but the behavior of their connections is complicated. Through this study, it is aimed to investigate the performance and behavior of different connection configurations between concrete filled steel tube columns and bracing diagonals through an experimental program. The study included 12 connection subassemblies consisting of a fixed length steel tube and gusset plate connected to the tube end with different details tested under half cyclic loading. A notable effect was observed on the behavior of the connections due to its detailing changes with respect to capacity, failure mode, ductility, and stress distribution.

  4. Real World Connections Through Videoconferences

    Science.gov (United States)

    Peterson, Ruth; Lytle, John (Technical Monitor)

    2002-01-01

    The Learning Technologies Project (LTP) is a partner in the National Aeronautics and Space Administration's (NASA's) educational technology program unit, an electronic community center that fosters interaction, collaboration, and sharing among educators, learners, and scientists. The goal of the NASA Glenn Research Center's Learning Technologies Project is to increase students' interest and proficiency in mathematics, science, and technology through the use of computing and communications technology and by using NASA's mission in aerospace technology as a theme. The primary components are: (1) Beginner's Guide to Aeronautics, including interactive simulation packages and teacher-created online activities. (2) NASA Virtual Visits, videoconferences (with online pre-post-conference activities) connecting students and teachers to NASA scientists and researchers.

  5. Delta connected resonant snubber circuit

    Science.gov (United States)

    Lai, J.S.; Peng, F.Z.; Young, R.W. Sr.; Ott, G.W. Jr.

    1998-01-20

    A delta connected, resonant snubber-based, soft switching, inverter circuit achieves lossless switching during dc-to-ac power conversion and power conditioning with minimum component count and size. Current is supplied to the resonant snubber branches solely by the dc supply voltage through the main inverter switches and the auxiliary switches. Component count and size are reduced by use of a single semiconductor switch in the resonant snubber branches. Component count is also reduced by maximizing the use of stray capacitances of the main switches as parallel resonant capacitors. Resonance charging and discharging of the parallel capacitances allows lossless, zero voltage switching. In one embodiment, circuit component size and count are minimized while achieving lossless, zero voltage switching within a three-phase inverter. 36 figs.

  6. A Building Connecting Separated Communities

    DEFF Research Database (Denmark)

    Axel, Erik

    , and the hallways had to accomodate for people to stop up and talk together. Washing machines were set-up in locations behind the kitchens with no doors between them, the idea being that you could enter the kitchen and socialize while the machine washed. To accomodate for present developments cables for internet...... with students from other dormitories, and connect with the Danes from other sections of the building isolating themselves. The janitor was surprised at the supposed function of the washing machines. Since other dormitories at the campus did not provide washing machines, the ones at the house investigated were...... in constant use, overloaded and noisy, making people stay away from the kitchen. With point of departure in this case, the nature of the spatial arrangements for the daily conduct of life are sketched out. The kitchen, hallways, washing machines and hotspots will be discussed as arrangements for accidental...

  7. Proliferating Connections and Communicating Convergence

    Directory of Open Access Journals (Sweden)

    Aylish Wood

    2008-01-01

    Full Text Available In this paper I use the work of Niklas Luhmann to explore what pressure the concept of convergence exerts over how we communicate about the changing expressive practices of digital games following the emergence of digital technologies. My claim will be that in its current form, convergence privileges either the human users of technological platforms, or the combination of aesthetic conventions from different media what connects is either the user or the aesthetic code. While neither of these two positions would be likely to deny a reliance on the interplay between humans and technologies, such an interplay is taken for granted rather than explored. By using Luhmann’s version of systems theory, I argue that we can more effectively grasp the interplay of human and technological participants by understanding their combined roles in changing expressive practices.

  8. Connecting cognition and consumer choice.

    Science.gov (United States)

    Bartels, Daniel M; Johnson, Eric J

    2015-02-01

    We describe what can be gained from connecting cognition and consumer choice by discussing two contexts ripe for interaction between the two fields. The first-context effects on choice-has already been addressed by cognitive science yielding insights about cognitive process but there is promise for more interaction. The second is learning and representation in choice where relevant theories in cognitive science could be informed by consumer choice, and in return, could pose and answer new questions. We conclude by discussing how these two fields of research stand to benefit from more interaction, citing examples of how interfaces of cognitive science with other fields have been illuminating for theories of cognition. Copyright © 2014 Elsevier B.V. All rights reserved.

  9. Investigation into Methods for Predicting Connection Temperatures

    Directory of Open Access Journals (Sweden)

    K. Anderson

    2009-01-01

    Full Text Available The mechanical response of connections in fire is largely based on material strength degradation and the interactions between the various components of the connection. In order to predict connection performance in fire, temperature profiles must initially be established in order to evaluate the material strength degradation over time. This paper examines two current methods for predicting connection temperatures: The percentage method, where connection temperatures are calculated as a percentage of the adjacent beam lower-flange, mid-span temperatures; and the lumped capacitance method, based on the lumped mass of the connection. Results from the percentage method do not correlate well with experimental results, whereas the lumped capacitance method shows much better agreement with average connection temperatures. A 3D finite element heat transfer model was also created in Abaqus, and showed good correlation with experimental results. 

  10. Radiotherapy in patients with connective tissue diseases.

    Science.gov (United States)

    Giaj-Levra, Niccolò; Sciascia, Savino; Fiorentino, Alba; Fersino, Sergio; Mazzola, Rosario; Ricchetti, Francesco; Roccatello, Dario; Alongi, Filippo

    2016-03-01

    The decision to offer radiotherapy in patients with connective tissue diseases continues to be challenging. Radiotherapy might trigger the onset of connective tissue diseases by increasing the expression of self-antigens, diminishing regulatory T-cell activity, and activating effectors of innate immunity (dendritic cells) through Toll-like receptor-dependent mechanisms, all of which could potentially lead to breaks of immune tolerance. This potential risk has raised some debate among radiation oncologists about whether patients with connective tissue diseases can tolerate radiation as well as people without connective tissue diseases. Because the number of patients with cancer and connective tissue diseases needing radiotherapy will probably increase due to improvements in medical treatment and longer life expectancy, the issue of interactions between radiotherapy and connective tissue diseases needs to be clearer. In this Review, we discuss available data and evidence for patients with connective tissue diseases treated with radiotherapy. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. Random geometric graphs with general connection functions.

    Science.gov (United States)

    Dettmann, Carl P; Georgiou, Orestis

    2016-03-01

    In the original (1961) Gilbert model of random geometric graphs, nodes are placed according to a Poisson point process, and links formed between those within a fixed range. Motivated by wireless ad hoc networks "soft" or "probabilistic" connection models have recently been introduced, involving a "connection function" H(r) that gives the probability that two nodes at distance r are linked (directly connect). In many applications (not only wireless networks), it is desirable that the graph is connected; that is, every node is linked to every other node in a multihop fashion. Here the connection probability of a dense network in a convex domain in two or three dimensions is expressed in terms of contributions from boundary components for a very general class of connection functions. It turns out that only a few quantities such as moments of the connection function appear. Good agreement is found with special cases from previous studies and with numerical simulations.

  12. Phonatory aerodynamics in connected speech.

    Science.gov (United States)

    Gartner-Schmidt, Jackie L; Hirai, Ryoji; Dastolfo, Christina; Rosen, Clark A; Yu, Lan; Gillespie, Amanda I

    2015-12-01

    1) Present phonatory aerodynamic data for healthy controls (HCs) in connected speech; 2) contrast these findings between HCs and patients with nontreated unilateral vocal fold paralysis (UVFP); 3) present pre- and post-vocal fold augmentation outcomes for patients with UVFP; 4) contrast data from patients with post-operative laryngeal augmentation to HCs. Retrospective, single-blinded. For phase I, 20 HC participants were recruited. For phase II, 20 patients with UVFP were age- and gender-matched to the 20 HC participants used in phase I. For phase III, 20 patients with UVFP represented a pre- and posttreatment cohort. For phase IV, 20 of the HC participants from phase I and 20 of the postoperative UVFP patients from phase III were used for direct comparison. Aerodynamic measures captured from a sample of the Rainbow Passage included: number of breaths, mean phonatory airflow rate, total duration of passage, inspiratory airflow duration, and expiratory airflow duration. The VHI-10 was also obtained pre- and postoperative laryngeal augmentation. All phonatory aerodynamic measures were significantly increased in patients with preoperative UVFP than the HC group. Patients with laryngeal augmentation took significantly less breaths, had less mean phonatory airflow rate during voicing, and had shorter inspiratory airflow duration than the preoperative UVFP group. None of the postoperative measures returned to HC values. Significant improvement in the Voice Handicap Index-10 scores postlaryngeal augmentation was also found. Methodology described in this study improves upon existing aerodynamic voice assessment by capturing characteristics germane to UVFP patient complaints and measuring change before and after laryngeal augmentation in connected speech. 4. © 2015 The American Laryngological, Rhinological and Otological Society, Inc.

  13. Connecting Leadership and Learning: Do Versatile Learners make Connective Leaders?

    Directory of Open Access Journals (Sweden)

    Jill L. Robinson

    2016-03-01

    Full Text Available Abstract Recent failures in leadership, suggest that creating better-quality leadership development programs is critical. In moving from theory to practice, this paper examined the relationship between learning style and leadership style which may enable us to move away from one-size-fits-all leadership development programs. Utilizing Kolb’s Experiential Learning Model and Connective Leadership theory, approximately 3600 college students were analyzed to discover whether versatility in learning styles translates into versatility in leadership styles. One group of versatile learners reported using a wider range of leadership styles suggesting that learning flexibility may transfer to leadership flexibility. Surprisingly, learners of all types reported utilizing Power and Intrinsic styles of leadership above all others. Implications for leadership development include considering individual differences when crafting leadership programs, matching learning styles to leader training, and the need to move beyond one set of leadership behaviors to increase flexibility in dealing with complex situations. Using a large sample rarely seen in management studies, this paper makes key contributions to the literature. 

  14. Structural Connectivity of the Developing Human Amygdala

    Science.gov (United States)

    Saygin, Zeynep M.; Osher, David E.; Koldewyn, Kami; Martin, Rebecca E.; Finn, Amy; Saxe, Rebecca; Gabrieli, John D.E.; Sheridan, Margaret

    2015-01-01

    A large corpus of research suggests that there are changes in the manner and degree to which the amygdala supports cognitive and emotional function across development. One possible basis for these developmental differences could be the maturation of amygdalar connections with the rest of the brain. Recent functional connectivity studies support this conclusion, but the structural connectivity of the developing amygdala and its different nuclei remains largely unstudied. We examined age related changes in the DWI connectivity fingerprints of the amygdala to the rest of the brain in 166 individuals of ages 5-30. We also developed a model to predict age based on individual-subject amygdala connectivity, and identified the connections that were most predictive of age. Finally, we segmented the amygdala into its four main nucleus groups, and examined the developmental changes in connectivity for each nucleus. We observed that with age, amygdalar connectivity becomes increasingly sparse and localized. Age related changes were largely localized to the subregions of the amygdala that are implicated in social inference and contextual memory (the basal and lateral nuclei). The central nucleus’ connectivity also showed differences with age but these differences affected fewer target regions than the basal and lateral nuclei. The medial nucleus did not exhibit any age related changes. These findings demonstrate increasing specificity in the connectivity patterns of amygdalar nuclei across age. PMID:25875758

  15. IDRC Connect Quick Reference Guide for Grantees

    International Development Research Centre (IDRC) Digital Library (Canada)

    Martine Lefebvre

    connect.idrc.ca. Note: Keep your IDRC Con- nect account access email in a safe place in the event you forget your username or need to reset your pass- word. Sign Out of IDRC. Connect. 1. From any page on. IDRC Connect, click on your name in the top right corner of the screen. 2. From the drop- down list, select. Sign Out ...

  16. IDRC Connect Quick Reference Guide for Grantees

    International Development Research Centre (IDRC) Digital Library (Canada)

    Martine Lefebvre

    connect.idrc.ca. Nota: Guarde su correo electró- nico de acceso a la cuenta de. IDRC Connect en un lugar seguro en caso de que olvide su nombre de usuario o necesite restablecer su contraseña. Cerrar sesió n en. IDRC Cónnect. 1. Desde cualquier pági- na de IDRC Connect, haga clic en su nom- bre en la esquina su-.

  17. Review on Cold-Formed Steel Connections

    OpenAIRE

    Lee, Yeong Huei; Tan, Cher Siang; Mohammad, Shahrin; Md Tahir, Mahmood; Shek, Poi Ngian

    2014-01-01

    The concept of cold-formed light steel framing construction has been widespread after understanding its structural characteristics with massive research works over the years. Connection serves as one of the important elements for light steel framing in order to achieve its structural stability. Compared to hot-rolled steel sections, cold-formed steel connections perform dissimilarity due to the thin-walled behaviour. This paper aims to review current researches on cold-formed steel connection...

  18. Connected Car: Quantified Self becomes Quantified Car

    OpenAIRE

    Melanie Swan

    2015-01-01

    The automotive industry could be facing a situation of profound change and opportunity in the coming decades. There are a number of influencing factors such as increasing urban and aging populations, self-driving cars, 3D parts printing, energy innovation, and new models of transportation service delivery (Zipcar, Uber). The connected car means that vehicles are now part of the connected world, continuously Internet-connected, generating and transmitting data, which on the one hand can be hel...

  19. The Curvature of the Hitchin Connection

    DEFF Research Database (Denmark)

    Andersen, Jørgen Ellegaard; Poulsen, Niccolo Skovgård

    In this paper we calculate the curvature of the Hitchin connection. We further show that a slight (possibly trivial) modification of the Hitchin connection has curvature equal to an explict given multiple of the Weil-Petersen symplectic form on Teichmüller space.......In this paper we calculate the curvature of the Hitchin connection. We further show that a slight (possibly trivial) modification of the Hitchin connection has curvature equal to an explict given multiple of the Weil-Petersen symplectic form on Teichmüller space....

  20. Drill pipe threaded nipple connection design development

    Science.gov (United States)

    Saruev, A. L.; Saruev, L. A.; Vasenin, S. S.

    2015-11-01

    The paper presents the analysis of the behavior of the drill pipe nipple connection under the additional load generated by power pulses. The strain wave propagation through the nipple thread connection of drill pipes to the bottomhole is studied in this paper. The improved design of the nipple thread connection is suggested using the obtained experimental and theoretical data. The suggested connection design allows not only the efficient transmission of strain wave energy to a drill bit but also the automation of making-up and breaking-out drill pipes.

  1. Essential Connectivity Areas - CEHC, (Raster) [ds620

    Data.gov (United States)

    California Department of Resources — The California Department of Transportation (Caltrans) and California Department of Fish and Game (CDFG) commissioned the California Essential Habitat Connectivity...

  2. Are We (T)here Yet? Qualitative Research in Education's Profuse and Contested Present

    Science.gov (United States)

    Wright, Handel Kashope

    2006-01-01

    This essay addresses the topic of the state of qualitative research in education by asserting that qualitative research in education is in quite a state. Drawing heavily on Denzin and Lincoln's periodization of qualitative research as a guide, it outlines the various competing developments from within and outside that are vying to characterize the…

  3. The Historical Development of Special Education: Humanitarian Rationality or 'Wild Profusion of Entangled Events'?

    Science.gov (United States)

    Armstrong, Felicity

    2002-01-01

    Discusses the historical development of special education in England and France using Michel Foucault's distinction between traditional and effective history. States attitudes and practices relating to difference are culture specific. Concludes that a variety of means should be used in challenging and interpreting other positions taken when…

  4. Profuse activity of blue electrical discharges at the tops of thunderstorms

    DEFF Research Database (Denmark)

    Chanrion, Olivier; Neubert, Torsten; Mogensen, Andreas

    2017-01-01

    a color video footage of thunderstorms over the Bay of Bengal from the International Space Station. The observations show a multitude of blue, km-scale, discharges at the cloud top layer at ~18 km altitude and a pulsating blue discharge propagating into the stratosphere reaching ~40 km altitude...

  5. A novel method linking neural connectivity to behavioral fluctuations: Behavior-regressed connectivity.

    Science.gov (United States)

    Passaro, Antony D; Vettel, Jean M; McDaniel, Jonathan; Lawhern, Vernon; Franaszczuk, Piotr J; Gordon, Stephen M

    2017-03-01

    During an experimental session, behavioral performance fluctuates, yet most neuroimaging analyses of functional connectivity derive a single connectivity pattern. These conventional connectivity approaches assume that since the underlying behavior of the task remains constant, the connectivity pattern is also constant. We introduce a novel method, behavior-regressed connectivity (BRC), to directly examine behavioral fluctuations within an experimental session and capture their relationship to changes in functional connectivity. This method employs the weighted phase lag index (WPLI) applied to a window of trials with a weighting function. Using two datasets, the BRC results are compared to conventional connectivity results during two time windows: the one second before stimulus onset to identify predictive relationships, and the one second after onset to capture task-dependent relationships. In both tasks, we replicate the expected results for the conventional connectivity analysis, and extend our understanding of the brain-behavior relationship using the BRC analysis, demonstrating subject-specific BRC maps that correspond to both positive and negative relationships with behavior. Comparison with Existing Method(s): Conventional connectivity analyses assume a consistent relationship between behaviors and functional connectivity, but the BRC method examines performance variability within an experimental session to understand dynamic connectivity and transient behavior. The BRC approach examines connectivity as it covaries with behavior to complement the knowledge of underlying neural activity derived from conventional connectivity analyses. Within this framework, BRC may be implemented for the purpose of understanding performance variability both within and between participants. Published by Elsevier B.V.

  6. MedlinePlus Connect: Frequently Asked Questions (FAQs)

    Science.gov (United States)

    ... page: https://medlineplus.gov/connect/faqs.html MedlinePlus Connect: Frequently Asked Questions (FAQs) To use the sharing ... for the MedlinePlus Connect email list . Using MedlinePlus Connect How does MedlinePlus Connect work? MedlinePlus Connect responds ...

  7. A Random Walk: Stumbling across Connections

    Science.gov (United States)

    Wasserman, Nicholas H.

    2015-01-01

    Finding and designing tasks that allow for students to make connections among mathematical ideas is important for mathematics educators. One such task, which affords students the opportunity to make connections and engage with significant mathematical ideas through a variety of problem-solving approaches, is described in this article. Three…

  8. The Listening Train: A Collaborative, Connective Aesthetics ...

    African Journals Online (AJOL)

    Key findings include the vital role of connective aesthetics in establishing imaginal thinking, moral intuition, empathy, participative parity, and emergence, and how these are important for transformation and establishing new capacities for ecological/global citizenship and collaborative intelligence. Keywords: Connective ...

  9. Water Treatment Technology - Cross-Connections.

    Science.gov (United States)

    Ross-Harrington, Melinda; Kincaid, G. David

    One of twelve water treatment technology units, this student manual on cross connections provides instructional materials for two competencies. (The twelve units are designed for a continuing education training course for public water supply operators.) The competencies focus on cross connections terminology and control devices. For each…

  10. Design of Bolted L-Flanged Connections

    DEFF Research Database (Denmark)

    Pedersen, Niels Leergaard

    2016-01-01

    In wind turbine towers the preferred design is circular tubes that are connected to each other by a bolted flange joint. The design is typically that of an L-flange resulting in an eccentrically loaded bolted connection. The eccentricity results in a non-linear relationship between external load...

  11. IDRC Connect | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    2015-07-20

    For projects approved after July 20, 2015, IDRC Connect must be used to submit technical reports project outputs funding requests for open access journal publishing charges You need a password to access IDRC Connect. When your project is approved, we email access information to the project leaders. Project leaders ...

  12. 78 FR 47211 - Connect America Fund

    Science.gov (United States)

    2013-08-05

    ... From the Federal Register Online via the Government Publishing Office FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 54 Connect America Fund AGENCY: Federal Communications Commission. ACTION: Final rule... associated with the Commission's Universal Service--Connect America Fund, Report and Order and Further Notice...

  13. Connections between quantum chromodynamics and condensed ...

    Indian Academy of Sciences (India)

    Recently some of the analyses that originated in condensed matter physics have found applications in QCD. Using examples we discuss some of the connections between the two fields and show how progress can be made by exploiting this connection. Some of the challenges that remain in the two fields are quite similar.

  14. IDRC Connect Quick Reference Guide for Grantees

    International Development Research Centre (IDRC) Digital Library (Canada)

    Martine Lefebvre

    How to obtain an IDRC Connect Account. Project Leaders. Project Leaders will receive an account confirmation email when a project is ap- proved, they are automatically granted access to IDRC Connect. Project Team Members. A Project Leader can request an account be created for project team members by completing ...

  15. Development of hippocampal functional connectivity during childhood.

    Science.gov (United States)

    Blankenship, Sarah L; Redcay, Elizabeth; Dougherty, Lea R; Riggins, Tracy

    2017-01-01

    The hippocampus is a medial temporal lobe structure involved in memory, spatial navigation, and regulation of stress responses, making it a structure critical to daily functioning. However, little is known about the functional development of the hippocampus during childhood due to methodological challenges of acquiring neuroimaging data in young participants. This is a critical gap given evidence that hippocampally-mediated behaviors (e.g., episodic memory) undergo rapid and important changes during childhood. To address this gap, the present investigation collected resting-state fMRI scans in 97, 4- to 10-year-old children. Whole brain seed-based analyses of anterior, posterior, and whole hippocampal connectivity were performed to identify regions demonstrating stable (i.e., age-controlled) connectivity profiles as well as age-related differences in connectivity. Results reveal that the hippocampus is a highly connected structure of the brain and that most of the major components of the adult network are evident during childhood, including both unique and overlapping connectivity between anterior and posterior regions. Despite widespread age-controlled connectivity, the strength of hippocampal connectivity with regions of lateral temporal lobes and the anterior cingulate increased throughout the studied age range. These findings have implications for future investigations of the development of hippocampally-mediated behaviors and methodological applications for the appropriateness of whole versus segmented hippocampal seeds in connectivity analyses. Hum Brain Mapp 38:182-201, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  16. Connections up to homotopy and characteristic classes

    NARCIS (Netherlands)

    Crainic, M.

    2000-01-01

    The aim of this note is to clarify the relevance of connections up to homotopy to the theory of characteristic classes and to present an application to the characteristic classes of algebroids and of Poisson manifolds in particular We have already remarked that such connections up to

  17. Connection overlap deviation analysis of pentamode metamaterials

    Science.gov (United States)

    Wang, Zhaohong; Liu, Guangshun; Cai, Chengxin; Chu, Yangyang; Li, Yucheng; Xu, Zhuo

    2017-12-01

    The adjacent double-cones of the pentamode metamaterials form a connection overlap for the non-180° angle connection, and the overlap leads to a connection overlap deviation between the actual effective narrow touch diameters d‧ and the defined narrow touch diameters d. The connection overlap deviation increases with the increasing of wide touch diameters D of the double-cones of the pentamode metamaterials with linear outside profile cones. In order to decrease the influence of the connection overlap deviation on the pentamode metamaterials, three types of pentamode metamaterials with small connection overlap (second and third order polynomial outside profile cones structures and the cones stacked by the cylinders-frustums) are proposed and studied in this paper. The connection overlap deviations of pentamode metamaterials with different outside profile cones are analyzed, the phononic band structures are calculated, and the ratio of bulk modulus B to shear modulus G are analyzed for evaluating fluid property. The results show that the pentamode metamaterials proposed by us have smaller connection overlap deviation and more excellent fluid properties than the pentamode metamaterials with linear outside profile cones. The ratio of bulk modulus to shear modulus can be increased by 7.47%–215.92% with the increasing of D from 1 mm to 9.6 mm.

  18. Are we connected? : Ports in Global Networks

    NARCIS (Netherlands)

    R.A. Zuidwijk (Rob)

    2015-01-01

    markdownabstractAbstract Global supply chains are built on organizational, information, and logistics networks. Ports are connected via these networks and also need to connect these networks. Synchromodality is an innovative concept for container transportation, and the port plays an important

  19. Voltage Quality of Grid Connected Wind Turbines

    DEFF Research Database (Denmark)

    Chen, Zhe; Blaabjerg, Frede; Sun, Tao

    2004-01-01

    Grid connected wind turbines may cause quality problems, such as voltage variation and flicker. This paper discusses the voltage variation and flicker emission of grid connected wind turbines with doubly-fed induction generators. A method to compensate flicker by using a voltage source converter...... (VSC) based STATCOM is presented, which shows it is an efficient mean to improve voltage quality....

  20. Connected digit speech recognition system for Malayalam

    Indian Academy of Sciences (India)

    A connected digit speech recognition is important in many applications such as automated banking system, catalogue-dialing, automatic data entry, automated banking system, etc. This paper presents an optimum speaker-independent connected digit recognizer for Malayalam language. The system employs Perceptual ...

  1. Connecting Functions in Geometry and Algebra

    Science.gov (United States)

    Steketee, Scott; Scher, Daniel

    2016-01-01

    One goal of a mathematics education is that students make significant connections among different branches of mathematics. Connections--such as those between arithmetic and algebra, between two-dimensional and three-dimensional geometry, between compass-and-straight-edge constructions and transformations, and between calculus and analytic…

  2. 29 CFR Appendix H to Subpart R of... - Double Connections: Illustration of a Clipped End Connection and a Staggered Connection: Non...

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 8 2010-07-01 2010-07-01 false Double Connections: Illustration of a Clipped End Connection and a Staggered Connection: Non-Mandatory Guidelines for Complying With § 1926.756(c)(1) H...: Illustration of a Clipped End Connection and a Staggered Connection: Non-Mandatory Guidelines for Complying...

  3. Directional connectivity in hydrology and ecology.

    Science.gov (United States)

    Larsen, Laurel G; Choi, Jungyill; Nungesser, Martha K; Harvey, Judson W

    2012-12-01

    Quantifying hydrologic and ecological connectivity has contributed to understanding transport and dispersal processes and assessing ecosystem degradation or restoration potential. However, there has been little synthesis across disciplines. The growing field of ecohydrology and recent recognition that loss of hydrologic connectivity is leading to a global decline in biodiversity underscore the need for a unified connectivity concept. One outstanding need is a way to quantify directional connectivity that is consistent, robust to variations in sampling, and transferable across scales or environmental settings. Understanding connectivity in a particular direction (e.g., streamwise, along or across gradient, between sources and sinks, along cardinal directions) provides critical information for predicting contaminant transport, planning conservation corridor design, and understanding how landscapes or hydroscapes respond to directional forces like wind or water flow. Here we synthesize progress on quantifying connectivity and develop a new strategy for evaluating directional connectivity that benefits from use of graph theory in ecology and percolation theory in hydrology. The directional connectivity index (DCI) is a graph-theory based, multiscale metric that is generalizable to a range of different structural and functional connectivity applications. It exhibits minimal sensitivity to image rotation or resolution within a given range and responds intuitively to progressive, unidirectional change. Further, it is linearly related to the integral connectivity scale length--a metric common in hydrology that correlates well with actual fluxes--but is less computationally challenging and more readily comparable across different landscapes. Connectivity-orientation curves (i.e., directional connectivity computed over a range of headings) provide a quantitative, information-dense representation of environmental structure that can be used for comparison or detection of

  4. Directional connectivity in hydrology and ecology

    Science.gov (United States)

    Larsen, Laurel G.; Choi, Jungyill; Nungesser, Martha K.; Harvey, Judson W.

    2012-01-01

    Quantifying hydrologic and ecological connectivity has contributed to understanding transport and dispersal processes and assessing ecosystem degradation or restoration potential. However, there has been little synthesis across disciplines. The growing field of ecohydrology and recent recognition that loss of hydrologic connectivity is leading to a global decline in biodiversity underscore the need for a unified connectivity concept. One outstanding need is a way to quantify directional connectivity that is consistent, robust to variations in sampling, and transferable across scales or environmental settings. Understanding connectivity in a particular direction (e.g., streamwise, along or across gradient, between sources and sinks, along cardinal directions) provides critical information for predicting contaminant transport, planning conservation corridor design, and understanding how landscapes or hydroscapes respond to directional forces like wind or water flow. Here we synthesize progress on quantifying connectivity and develop a new strategy for evaluating directional connectivity that benefits from use of graph theory in ecology and percolation theory in hydrology. The directional connectivity index (DCI) is a graph-theory based, multiscale metric that is generalizable to a range of different structural and functional connectivity applications. It exhibits minimal sensitivity to image rotation or resolution within a given range and responds intuitively to progressive, unidirectional change. Further, it is linearly related to the integral connectivity scale length—a metric common in hydrology that correlates well with actual fluxes—but is less computationally challenging and more readily comparable across different landscapes. Connectivity-orientation curves (i.e., directional connectivity computed over a range of headings) provide a quantitative, information-dense representation of environmental structure that can be used for comparison or detection of

  5. Connectiveness and civility in online learning.

    Science.gov (United States)

    Rieck, Susan; Crouch, Laura

    2007-11-01

    As the classroom shifts from teacher-centered to learner-centered and from face-to-face to online, nursing faculty members are challenged to promote a sense of connectiveness and social interaction. Making connectiveness more elusive is the perception of rude, impolite, or unkind communication. The purpose of this descriptive-exploratory study was to examine perceptions of connectiveness and civility in online nursing courses. Ninety-six students in four nursing programs participated in the study. Strategies that promote connectiveness with peers are in-person activities whenever possible and discussion assignments that include social activities. Timely feedback when responding to questions and prompt grading are important for student-to-instructor connectiveness. Thirty-five percent of the students encountered rude or unkind communication with peers, and 60% reported incivility from instructors. Their suggestions for effective handling of rude communication included addressing the behavior privately, giving guidance about netiquette, and defining what constitutes rude behavior.

  6. Brain Connectivity Analysis: A Short Survey

    Directory of Open Access Journals (Sweden)

    E. W. Lang

    2012-01-01

    Full Text Available This short survey the reviews recent literature on brain connectivity studies. It encompasses all forms of static and dynamic connectivity whether anatomical, functional, or effective. The last decade has seen an ever increasing number of studies devoted to deduce functional or effective connectivity, mostly from functional neuroimaging experiments. Resting state conditions have become a dominant experimental paradigm, and a number of resting state networks, among them the prominent default mode network, have been identified. Graphical models represent a convenient vehicle to formalize experimental findings and to closely and quantitatively characterize the various networks identified. Underlying these abstract concepts are anatomical networks, the so-called connectome, which can be investigated by functional imaging techniques as well. Future studies have to bridge the gap between anatomical neuronal connections and related functional or effective connectivities.

  7. Connecting network properties of rapidly disseminating epizoonotics.

    Directory of Open Access Journals (Sweden)

    Ariel L Rivas

    Full Text Available To effectively control the geographical dissemination of infectious diseases, their properties need to be determined. To test that rapid microbial dispersal requires not only susceptible hosts but also a pre-existing, connecting network, we explored constructs meant to reveal the network properties associated with disease spread, which included the road structure.Using geo-temporal data collected from epizoonotics in which all hosts were susceptible (mammals infected by Foot-and-mouth disease virus, Uruguay, 2001; birds infected by Avian Influenza virus H5N1, Nigeria, 2006, two models were compared: 1 'connectivity', a model that integrated bio-physical concepts (the agent's transmission cycle, road topology into indicators designed to measure networks ('nodes' or infected sites with short- and long-range links, and 2 'contacts', which focused on infected individuals but did not assess connectivity.THE CONNECTIVITY MODEL SHOWED FIVE NETWORK PROPERTIES: 1 spatial aggregation of cases (disease clusters, 2 links among similar 'nodes' (assortativity, 3 simultaneous activation of similar nodes (synchronicity, 4 disease flows moving from highly to poorly connected nodes (directionality, and 5 a few nodes accounting for most cases (a "20:80" pattern. In both epizoonotics, 1 not all primary cases were connected but at least one primary case was connected, 2 highly connected, small areas (nodes accounted for most cases, 3 several classes of nodes were distinguished, and 4 the contact model, which assumed all primary cases were identical, captured half the number of cases identified by the connectivity model. When assessed together, the synchronicity and directionality properties explained when and where an infectious disease spreads.Geo-temporal constructs of Network Theory's nodes and links were retrospectively validated in rapidly disseminating infectious diseases. They distinguished classes of cases, nodes, and networks, generating information usable

  8. Ecological connectivity networks in rapidly expanding cities.

    Science.gov (United States)

    Nor, Amal Najihah M; Corstanje, Ron; Harris, Jim A; Grafius, Darren R; Siriwardena, Gavin M

    2017-06-01

    Urban expansion increases fragmentation of the landscape. In effect, fragmentation decreases connectivity, causes green space loss and impacts upon the ecology and function of green space. Restoration of the functionality of green space often requires restoring the ecological connectivity of this green space within the city matrix. However, identifying ecological corridors that integrate different structural and functional connectivity of green space remains vague. Assessing connectivity for developing an ecological network by using efficient models is essential to improve these networks under rapid urban expansion. This paper presents a novel methodological approach to assess and model connectivity for the Eurasian tree sparrow (Passer montanus) and Yellow-vented bulbul (Pycnonotus goiavier) in three cities (Kuala Lumpur, Malaysia; Jakarta, Indonesia and Metro Manila, Philippines). The approach identifies potential priority corridors for ecological connectivity networks. The study combined circuit models, connectivity analysis and least-cost models to identify potential corridors by integrating structure and function of green space patches to provide reliable ecological connectivity network models in the cities. Relevant parameters such as landscape resistance and green space structure (vegetation density, patch size and patch distance) were derived from an expert and literature-based approach based on the preference of bird behaviour. The integrated models allowed the assessment of connectivity for both species using different measures of green space structure revealing the potential corridors and least-cost pathways for both bird species at the patch sites. The implementation of improvements to the identified corridors could increase the connectivity of green space. This study provides examples of how combining models can contribute to the improvement of ecological networks in rapidly expanding cities and demonstrates the usefulness of such models for

  9. Towards quantitative connectivity analysis: reducing tractography biases.

    Science.gov (United States)

    Girard, Gabriel; Whittingstall, Kevin; Deriche, Rachid; Descoteaux, Maxime

    2014-09-01

    Diffusion MRI tractography is often used to estimate structural connections between brain areas and there is a fast-growing interest in quantifying these connections based on their position, shape, size and length. However, a portion of the connections reconstructed with tractography is biased by their position, shape, size and length. Thus, connections reconstructed are not equally distributed in all white matter bundles. Quantitative measures of connectivity based on the streamline distribution in the brain such as streamline count (density), average length and spatial extent (volume) are biased by erroneous streamlines produced by tractography algorithms. In this paper, solutions are proposed to reduce biases in the streamline distribution. First, we propose to optimize tractography parameters in terms of connectivity. Then, we propose to relax the tractography stopping criterion with a novel probabilistic stopping criterion and a particle filtering method, both based on tissue partial volume estimation maps calculated from a T1-weighted image. We show that optimizing tractography parameters, stopping and seeding strategies can reduce the biases in position, shape, size and length of the streamline distribution. These tractography biases are quantitatively reported using in-vivo and synthetic data. This is a critical step towards producing tractography results for quantitative structural connectivity analysis. Copyright © 2014 Elsevier Inc. All rights reserved.

  10. Abnormal interhemispheric connectivity in male psychopathic offenders.

    Science.gov (United States)

    Hoppenbrouwers, Sylco S; De Jesus, Danilo R; Sun, Yinming; Stirpe, Tania; Hofman, Dennis; McMaster, Jeff; Hughes, Ginny; Daskalakis, Zafiris J; Schutter, Dennis J L G

    2014-01-01

    Psychopathic offenders inevitably violate interpersonal norms and frequently resort to aggressive and criminal behaviour. The affective and cognitive deficits underlying these behaviours have been linked to abnormalities in functional interhemispheric connectivity. However, direct neurophysiological evidence for dysfunctional connectivity in psychopathic offenders is lacking. We used transcranial magnetic stimulation combined with electroencephalography to examine interhemispheric connectivity in the dorsolateral and motor cortex in a sample of psychopathic offenders and healthy controls. We also measured intracortical inhibition and facilitation over the left and right motor cortex to investigate the effects of local cortical processes on interhemispheric connectivity. We enrolled 17 psychopathic offenders and 14 controls in our study. Global abnormalities in right to left functional connectivity were observed in psychopathic offenders compared with controls. Furthermore, in contrast to controls, psychopathic offenders showed increased intracortical inhibition in the right, but not the left, hemisphere. The relatively small sample size limited the sensitivity to show that the abnormalities in interhemispheric connectivity were specifically related to the dorsolateral prefrontal cortex in psychopathic offenders. To our knowledge, this study provides the first neurophysiological evidence for abnormal interhemispheric connectivity in psychopathic offenders and may further our understanding of the disruptive antisocial behaviour of these offenders.

  11. Low pore connectivity in natural rock

    Science.gov (United States)

    Hu, Qinhong; Ewing, Robert P.; Dultz, Stefan

    2012-05-01

    As repositories for CO2 and radioactive waste, as oil and gas reservoirs, and as contaminated sites needing remediation, rock formations play a central role in energy and environmental management. The connectivity of the rock's porespace strongly affects fluid flow and solute transport. This work examines pore connectivity and its implications for fluid flow and chemical transport. Three experimental approaches (imbibition, tracer concentration profiles, and imaging) were used in combination with network modeling. In the imbibition results, three types of imbibition slope [log (cumulative imbibition) vs. log (imbibition time)] were found: the classical 0.5, plus 0.26, and 0.26 transitioning to 0.5. The imbibition slope of 0.26 seen in Indiana sandstone, metagraywacke, and Barnett shale indicates low pore connectivity, in contrast to the slope of 0.5 seen in the well-connected Berea sandstone. In the tracer profile work, rocks exhibited different distances to the plateau porosity, consistent with the pore connectivity from the imbibition tests. Injection of a molten metal into connected pore spaces, followed by 2-D imaging of the solidified alloy in polished thin sections, allowed direct assessment of pore structure and lateral connection in the rock samples. Pore-scale network modeling gave results consistent with measurements, confirming pore connectivity as the underlying cause of both anomalous behaviors: imbibition slope not having the classical value of 0.5, and accessible porosity being a function of distance from the edge. A poorly connected porespace will exhibit anomalous behavior in fluid flow and chemical transport, such as a lower imbibition slope (in air-water system) and diffusion rate than expected from classical behavior.

  12. Altered thalamic functional connectivity in multiple sclerosis

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Yaou; Liang, Peipeng; Duan, Yunyun; Huang, Jing; Ren, Zhuoqiong; Jia, Xiuqin [Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing 100053 (China); Dong, Huiqing; Ye, Jing [Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053 (China); Shi, Fu-Dong [Department of Neurology and Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin 300052 (China); Butzkueven, Helmut [Department of Medicine, University of Melbourne, Parkville 3010 (Australia); Li, Kuncheng, E-mail: kunchengli55@gmail.com [Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing 100053 (China)

    2015-04-15

    Highlights: •We demonstrated decreased connectivity between thalamus and cortical regions in MS. •Increased intra- and inter-thalamic connectivity was also observed in MS. •The increased functional connectivity is attenuated by increasing disease duration. -- Abstract: Objective: To compare thalamic functional connectivity (FC) in patients with multiple sclerosis (MS) and healthy controls (HC), and correlate these connectivity measures with other MRI and clinical variables. Methods: We employed resting-state functional MRI (fMRI) to examine changes in thalamic connectivity by comparing thirty-five patients with MS and 35 age- and sex-matched HC. Thalamic FC was investigated by correlating low frequency fMRI signal fluctuations in thalamic voxels with voxels in all other brain regions. Additionally thalamic volume fraction (TF), T2 lesion volume (T2LV), EDSS and disease duration were recorded and correlated with the FC changes. Results: MS patients were found to have a significantly lower TF than HC in bilateral thalami. Compared to HC, the MS group showed significantly decreased FC between thalamus and several brain regions including right middle frontal and parahippocampal gyri, and the left inferior parietal lobule. Increased intra- and inter-thalamic FC was observed in the MS group compared to HC. These FC alterations were not correlated with T2LV, thalamic volume or lesions. In the MS group, however, there was a negative correlation between disease duration and inter-thalamic connectivity (r = −0.59, p < 0.001). Conclusion: We demonstrated decreased FC between thalamus and several cortical regions, while increased intra- and inter-thalamic connectivity in MS patients. These complex functional changes reflect impairments and/or adaptations that are independent of T2LV, thalamic volume or presence of thalamic lesions. The negative correlation between disease duration and inter-thalamic connectivity could indicate an adaptive role of thalamus that is

  13. Depression: a psychiatric nursing theory of connectivity.

    Science.gov (United States)

    Feely, M; Long, A

    2009-10-01

    This paper presents a theory of connectivity, which was formulated from the findings of a Classical Grounded Theory study that was designed to capture a sample of people's perceptions of living with depression or caring for individuals with depression. Data were collected from: (1) a focus group consisting of people with depression (n = 7), of which five were patients in the community and two were nurses; (2) one-to-one interviews with patients in the community (n = 5) and nurses (n = 5), three of whom had experienced depression from both sides of the caring process; and (3) two 'happy accident' focus groups (n = 25; n = 18) comprising of healthcare workers with a shared understanding of depression. Purposeful sampling was used initially. Thereafter, in keeping with one of the key tenets of grounded theory, theoretical sampling was used until theoretical saturation occurred. Data were analysed using the constant comparative approach together with the NVivo qualitative analysis software package. The core category that emerged was 'connectivity' relating to the connections and disconnections, which people make in their lives. Six key categories emerged all of which were integrated with the core category. Hence, connectivity provided a significant platform for understanding and responding to the life experience of depression. They were: (1) life encounters on the journey to naming; (2) depression: What's in a name? The silent thief; (3) tentative steps to health care; (4) connective encounters and challenges; (5) connecting with self; and (6) self-connection maintenance. Subsequently, a theory, 'Depression: a psychiatric nursing theory of connectivity', surfaced from the overall findings. We argue that this theory of connectivity provides a framework that people working in the field of holistic treatment and care could use to better understand and respond to the life experience of people living with depression.

  14. PROCESS OF ELECTRICAL CONNECTION OF PHOTOVOLTAIC DEVICES

    DEFF Research Database (Denmark)

    2012-01-01

    A photovoltaic cell module comprising at least two serially connected photovoltaic cells on a common substrate, wherein the cells each comprise a first electrode layer, a first charge selective layer, a light harvesting layer which comprises an organic conjugated polymer, and a second charge...... of the pair, which connection is made through the light harvesting layer common to the at least one pair of cells, without forming an electrical connection with the first electrode of the first cell or the second charge selective layer of the second cell; and a method of making such a photovoltaic cell module....

  15. Electrical connection structure for a superconductor element

    Science.gov (United States)

    Lallouet, Nicolas; Maguire, James

    2010-05-04

    The invention relates to an electrical connection structure for a superconductor element cooled by a cryogenic fluid and connected to an electrical bushing, which bushing passes successively through an enclosure at an intermediate temperature between ambient temperature and the temperature of the cryogenic fluid, and an enclosure at ambient temperature, said bushing projecting outside the ambient temperature enclosure. According to the invention, said intermediate enclosure is filled at least in part with a solid material of low thermal conductivity, such as a polyurethane foam or a cellular glass foam. The invention is applicable to connecting a superconductor cable at cryogenic temperature to a device for equipment at ambient temperature.

  16. Connectivity in sol-gel silica glasses

    Directory of Open Access Journals (Sweden)

    Wander L. Vasconcelos

    1998-07-01

    Full Text Available In this work it is carried out a review on structural parameters related to the evaluation of pore connectivity of nanostructures. The work describes parameters and methods of evaluation of geometric parameters. The concepts of connectivity are applied to silica gels and glasses obtained from sol-gel process. The study of pores connectivity was carried out using a combination of geometric modeling and experimental evaluation of specific surface area and pore volume. The permeability of the pore structure is evaluated and a permeability geometric factor, Pg, is proposed.

  17. Regional vulnerability of longitudinal cortical association connectivity: Associated with structural network topology alterations in preterm children with cerebral palsy.

    Science.gov (United States)

    Ceschin, Rafael; Lee, Vince K; Schmithorst, Vince; Panigrahy, Ashok

    2015-01-01

    alteration in eigenvector centrality, clustering coefficient (inter-regional) and participation co-efficient (inter-modular) alterations of frontal-striatal and fronto-limbic nodes suggesting re-organization of these pathways. Both along tract and structural topology network measurements correlated strongly with motor and visual clinical outcome scores. This study shows the value of combining along-tract analysis and structural network topology in depicting not only selective parietal occipital regional vulnerability but also reorganization of frontal-striatal and frontal-limbic pathways in preterm children with cerebral palsy. These finding also support the concept that widespread, but selective posterior-anterior neural network connectivity alterations in preterm children with cerebral palsy likely contribute to the pathogenesis of neurosensory and cognitive impairment in this group.

  18. 'Implant-abutment interface', 'Abutment connection'

    African Journals Online (AJOL)

    Abutment connection',. 'External Hex', 'Internal hex', 'Morse taper' alone or in combination. Option of related articles was also utilized. Related English language publications were reviewed excluding case reports and individual product based ...

  19. The Listening Train: A Collaborative, Connective Aesthetics ...

    African Journals Online (AJOL)

    in establishing imaginal thinking, moral intuition, empathy, participative parity, and emergence, and how these are important for transformation and establishing new capacities for ecological/global citizenship and collaborative intelligence. Keywords: Connective aesthetics, transgressive learning, transformation, social ...

  20. Asthma Research: The NIH–NJRC Connection

    Science.gov (United States)

    ... Bar Home Current Issue Past Issues Special Section Asthma Research: The NIH–NJRC Connection Past Issues / Fall ... the many ways that NIH supports and promotes asthma research is through its strong relationship with National ...

  1. Social media and (dis)connectivity

    DEFF Research Database (Denmark)

    Tække, Jesper

    . In the present society we also see signs of new dis-connectivity, i.e. fake news, political polarization, and economic and democratic inequality. In the final section the paper analyse such problems triggered by digital media. Also the paper point out some new possibilities triggered by the acquisition of social...... and his theory of communication media in a synthesis with Medium Theory (especially Meyrowitz). As a starting point the acquisition of oral language made communicative connections and thereby society possible. Later the media of writing, print and analogue electronic media meant new possibilities...... for social systems to develop structures with new forms of communicative connections. Even though society only is possible because of communication media and gets new possibilities for the formation of new structures providing it with new connection possibilities, in the beginning a new communication medium...

  2. Periodic words connected with the Fibonacci words

    Directory of Open Access Journals (Sweden)

    G. M. Barabash

    2016-06-01

    Full Text Available In this paper we introduce two families of periodic words (FLP-words of type 1 and FLP-words of type 2 that are connected with the Fibonacci words and investigated their properties.

  3. Switch-connected HyperX network

    Science.gov (United States)

    Chen, Dong; Heidelberger, Philip

    2018-02-13

    A network system includes a plurality of sub-network planes and global switches. The sub-network planes have a same network topology as each other. Each of the sub-network planes includes edge switches. Each of the edge switches has N ports. Each of the global switches is configured to connect a group of edge switches at a same location in the sub-network planes. In each of the sub-network planes, some of the N ports of each of the edge switches are connected to end nodes, and others of the N ports are connected to other edge switches in the same sub-network plane, other of the N ports are connected to at least one of the global switches.

  4. Low-stress bicycling and network connectivity.

    Science.gov (United States)

    2012-05-01

    For a bicycling network to attract the widest possible segment of the population, its most fundamental attribute should be low-stress connectivity, that is, providing routes between peoples origins and destinations that do not require cyclists to ...

  5. Brain Connectivity Related to Working Memory Performance

    National Research Council Canada - National Science Library

    Hampson, Michelle; Driesen, Naomi R; Skudlarski, Pawel; Gore, John C; Constable, R. Todd

    2006-01-01

    .... This study investigated the functional connectivity between the PCC and MFG/vACC during a working memory task and at rest by examining temporal correlations in magnetic resonance signal levels between the regions...

  6. Embedded adhesive connection for laminated glass plates

    DEFF Research Database (Denmark)

    Hansen, Jens Zangenberg; Poulsen, S.H.; Bagger, A.

    2012-01-01

    The structural behavior of a new connection design, the embedded adhesive connection, used for laminated glass plates is investigated. The connection consists of an aluminum plate encapsulated in-between two adjacent triple layered laminated glass plates. Fastening between glass and aluminum...... is ensured using a structural adhesive. At first, the elastic and viscoelastic material properties of the adhesive are identified where the influence of load-rate and failure properties are also examined. Through an inverse analysis using the finite element method, the experimental observations...... are replicated to identify a material model of the adhesive. The material model consists of an elastic and linear viscoelastic formulation suitable for a numerical implementation of the material. Based on two relevant load cases, out-of-plane bending and in-plane shear, the connection performance is investigated...

  7. Partial connectivity increases cultural accumulation within groups.

    Science.gov (United States)

    Derex, Maxime; Boyd, Robert

    2016-03-15

    Complex technologies used in most human societies are beyond the inventive capacities of individuals. Instead, they result from a cumulative process in which innovations are gradually added to existing cultural traits across many generations. Recent work suggests that a population's ability to develop complex technologies is positively affected by its size and connectedness. Here, we present a simple computer-based experiment that compares the accumulation of innovations by fully and partially connected groups of the same size in a complex fitness landscape. We find that the propensity to learn from successful individuals drastically reduces cultural diversity within fully connected groups. In comparison, partially connected groups produce more diverse solutions, and this diversity allows them to develop complex solutions that are never produced in fully connected groups. These results suggest that explanations of ancestral patterns of cultural complexity may need to consider levels of population fragmentation and interaction patterns between partially isolated groups.

  8. Better models are more effectively connected models

    Science.gov (United States)

    Nunes, João Pedro; Bielders, Charles; Darboux, Frederic; Fiener, Peter; Finger, David; Turnbull-Lloyd, Laura; Wainwright, John

    2016-04-01

    The concept of hydrologic and geomorphologic connectivity describes the processes and pathways which link sources (e.g. rainfall, snow and ice melt, springs, eroded areas and barren lands) to accumulation areas (e.g. foot slopes, streams, aquifers, reservoirs), and the spatial variations thereof. There are many examples of hydrological and sediment connectivity on a watershed scale; in consequence, a process-based understanding of connectivity is crucial to help managers understand their systems and adopt adequate measures for flood prevention, pollution mitigation and soil protection, among others. Modelling is often used as a tool to understand and predict fluxes within a catchment by complementing observations with model results. Catchment models should therefore be able to reproduce the linkages, and thus the connectivity of water and sediment fluxes within the systems under simulation. In modelling, a high level of spatial and temporal detail is desirable to ensure taking into account a maximum number of components, which then enables connectivity to emerge from the simulated structures and functions. However, computational constraints and, in many cases, lack of data prevent the representation of all relevant processes and spatial/temporal variability in most models. In most cases, therefore, the level of detail selected for modelling is too coarse to represent the system in a way in which connectivity can emerge; a problem which can be circumvented by representing fine-scale structures and processes within coarser scale models using a variety of approaches. This poster focuses on the results of ongoing discussions on modelling connectivity held during several workshops within COST Action Connecteur. It assesses the current state of the art of incorporating the concept of connectivity in hydrological and sediment models, as well as the attitudes of modellers towards this issue. The discussion will focus on the different approaches through which connectivity

  9. Connecting peripheral devices to Raspberry P

    OpenAIRE

    Fabčič, Simon

    2014-01-01

    My thesis deals with connecting peripheral devices to the Raspberry Pi. At first I presents the equipment I needed for programming. For the general hardware I used the single-board Raspberry Pi (model B) and installed the Raspbian operating system. There was a development environment for the Python programming language already installed on the computer, which I used. In the subsequent passages I presented how to connect the Raspberry Pi with peripheral devices and digital sensors using differ...

  10. SERVIR Town Hall - Connecting Space to Village

    Science.gov (United States)

    Limaye, Ashutosh S.; Searby, Nancy D.; Irwin, Daniel; Albers, Cerese

    2013-01-01

    SERVIR, a joint NASA-USAID project, strives to improve environmental decision making through the use of Earth observations, models, and geospatial technology innovations. SERVIR connects these assets with the needs of end users in Mesoamerica, East Africa, and Hindu Kush-Himalaya regions. This Town Hall meeting will engage the AGU community by exploring examples of connecting Space to Village with SERVIR science applications.

  11. Connecting Land-Based Networks to Ships

    Science.gov (United States)

    2013-06-01

    VSAT ) system. The stations, equipped with VSAT antennas, share the satellite’s transmission capacity to transmit to the station having the central hub...and base stations, which are connected to the ship’s VSAT system by which the voice and data connections from the phones are routed from the ship to...Maritime VSAT Communications Solutions, June 2010. [17] MCP Maritime Communications Partner, “Technology overview,” August 2012, http

  12. Subepithelial connective tissue graft: a case report

    OpenAIRE

    Juliana Alcarás Saraiva; Edson Alves de Campos; Rodrigo Cavassim; Shelon Cristina de Souza Pinto; Lucas Amaral Fontanari; Guilherme José Pimentel Lopes Oliveira; José Eduardo Cezar Sampaio

    2011-01-01

    Introduction and objective: Marginal tissue recession represents a common condition in Periodontology. Miller's Classes I and II recessions, in which the etiological factors are well diagnosed and eliminated, show great predictability of total coverage when the technique of subepithelial connective tissue graft is used. This technique success has been mainly attributed to the double blood supply for graft's nutrition, originating from the connective tissue of both the periosteum and flap. Cas...

  13. A Model of Trusted Connection Architecture

    OpenAIRE

    Zhang Xun; Wang Zhihao; Zhi Yong; Yuan Hui

    2017-01-01

    According to that traditional trusted network connection architecture (TNC) has limitations on dynamic network environment and the user behavior support, we develop TCA to propose a trusted connection architecture supporting behavior measurement (TCA-SBM), besides, the structure diagram of network architecture is given. Through introducing user behavior measure elements, TCA-SBM can conduct measurement on the whole network in time dimension periodically, and refine the measurement on network ...

  14. Wireless device connection problems and design solutions

    Science.gov (United States)

    Song, Ji-Won; Norman, Donald; Nam, Tek-Jin; Qin, Shengfeng

    2016-09-01

    Users, especially the non-expert users, commonly experience problems when connecting multiple devices with interoperability. While studies on multiple device connections are mostly concentrated on spontaneous device association techniques with a focus on security aspects, the research on user interaction for device connection is still limited. More research into understanding people is needed for designers to devise usable techniques. This research applies the Research-through-Design method and studies the non-expert users' interactions in establishing wireless connections between devices. The "Learning from Examples" concept is adopted to develop a study focus line by learning from the expert users' interaction with devices. This focus line is then used for guiding researchers to explore the non-expert users' difficulties at each stage of the focus line. Finally, the Research-through-Design approach is used to understand the users' difficulties, gain insights to design problems and suggest usable solutions. When connecting a device, the user is required to manage not only the device's functionality but also the interaction between devices. Based on learning from failures, an important insight is found that the existing design approach to improve single-device interaction issues, such as improvements to graphical user interfaces or computer guidance, cannot help users to handle problems between multiple devices. This study finally proposes a desirable user-device interaction in which images of two devices function together with a system image to provide the user with feedback on the status of the connection, which allows them to infer any required actions.

  15. Sensing coral reef connectivity pathways from space

    KAUST Repository

    Raitsos, Dionysios E.

    2017-08-18

    Coral reefs rely on inter-habitat connectivity to maintain gene flow, biodiversity and ecosystem resilience. Coral reef communities of the Red Sea exhibit remarkable genetic homogeneity across most of the Arabian Peninsula coastline, with a genetic break towards the southern part of the basin. While previous studies have attributed these patterns to environmental heterogeneity, we hypothesize that they may also emerge as a result of dynamic circulation flow; yet, such linkages remain undemonstrated. Here, we integrate satellite-derived biophysical observations, particle dispersion model simulations, genetic population data and ship-borne in situ profiles to assess reef connectivity in the Red Sea. We simulated long-term (>20 yrs.) connectivity patterns driven by remotely-sensed sea surface height and evaluated results against estimates of genetic distance among populations of anemonefish, Amphiprion bicinctus, along the eastern Red Sea coastline. Predicted connectivity was remarkably consistent with genetic population data, demonstrating that circulation features (eddies, surface currents) formulate physical pathways for gene flow. The southern basin has lower physical connectivity than elsewhere, agreeing with known genetic structure of coral reef organisms. The central Red Sea provides key source regions, meriting conservation priority. Our analysis demonstrates a cost-effective tool to estimate biophysical connectivity remotely, supporting coastal management in data-limited regions.

  16. Quantifying Connectivity in the Coastal Ocean

    Science.gov (United States)

    Mitarai, S.; Siegel, D.; Watson, J.; Dong, C.; McWilliams, J.

    2008-12-01

    The quantification of coastal connectivity is important for a wide range of real-world applications ranging from marine pollution to nearshore fisheries management. For these purposes, coastal connectivity is best defined as the probability that water parcels from one nearshore location are advected to another site over a given time interval. Here, we demonstrate how to quantify coastal connectivity using Lagrangian probability- density function (PDF) methods, a classic modeling approach for many turbulent applications, and numerical solutions of coastal circulation for the Southern California Bight. Mean dispersal patterns from a single release site (or Lagrangian PDFs) show a strong dependency to the particle-release location and seasonal variability, reflecting circulation patterns in the Southern California Bight. Strong interannual variations, responding to El Nino and La Nina transitions are also observed. Mean connectivity patterns, deduced from Lagrangian PDFs, is spatially heterogeneous for the advection time of around 30 days or less, resulting from distinctive circulation patterns, and becomes more homogeneous for a longer advection time. A given realization of connectivity is stochastic because of eddy-driven transport and synoptic wind forcing changes. In general, mainland sites are good sources while both Northern and Southern Channel Islands are poor source sites, although they receive substantial fluxes of water parcels from the mainland. The predicted connectivity gives useful information to ecological and other applications for the Southern California Bight (e.g., designing marine protected areas, understanding gene structures, and predicting the impact of a pollution event) and provide a path for assessing connectivity for other regions of the coastal ocean.

  17. Connectivity measures in EEG microstructural sleep elements

    Directory of Open Access Journals (Sweden)

    Dimitris eSakellariou

    2016-02-01

    Full Text Available During Non-Rapid Eye Movement sleep (NREM the brain is relatively disconnected from the environment, while connectedness between brain areas is also decreased. Evidence indicates that these dynamic connectivity changes are delivered by microstructural elements of sleep: short periods of environmental stimuli evaluation followed by sleep promoting procedures. The connectivity patterns of the latter, among other aspects of sleep microstructure, are still to be fully elucidated.We suggest here a methodology for the assessment and investigation of the connectivity patterns of EEG microstructural elements, such as sleep spindles. The methodology combines techniques in the preprocessing, estimation, error assessing and visualization of results levels in order to allow the detailed examination of the connectivity aspects (levels and directionality of information flow over frequency and time with notable resolution, while dealing with the volume conduction and EEG reference assessment. The high temporal and frequency resolution of the methodology will allow the association between the microelements and the dynamically forming networks that characterise them, and consequently possibly reveal aspects of the EEG microstructure. The proposed methodology is initially tested on artificially generated signals for proof of concept and subsequently applied to real EEG recordings via a custom built MATLAB-based tool developed for such studies. Preliminary results from 843 fast sleep spindles recorded in whole night sleep of 5 healthy volunteers indicate a prevailing pattern of interactions between centroparietal and frontal regions.We demonstrate hereby an opening to our knowledge attempt to estimate the scalp EEG connectivity that characterizes fast sleep spindles via an EEG-element connectivity methodology we propose. The application of the latter, via a computational tool we developed suggests it is able to investigate the connectivity patterns related to the

  18. Prioritizing connection requests in GMPLS-controlled optical networks

    DEFF Research Database (Denmark)

    Ruepp, Sarah Renée; Koster, A.; Andriolli, N.

    2009-01-01

    We prioritize bidirectional connection requests by combining dynamic connection provisioning with off-line optimization. Results show that the proposed approach decreases wavelength-converter usage, thereby allowing operators to reduce blocking-probably under bulk connection assignment or network...

  19. Optimization of thrie beam terminal end shoe connection.

    Science.gov (United States)

    2017-04-01

    Terminal thrie end shoes connect nested thrie beams to parapets or other bridge rail structure to provide a robust connectivity between a transition section and a rigid railing section. When connecting terminal end shoe to thrie beam transitions, the...

  20. Global malaria connectivity through air travel.

    Science.gov (United States)

    Huang, Zhuojie; Tatem, Andrew J

    2013-08-02

    Air travel has expanded at an unprecedented rate and continues to do so. Its effects have been seen on malaria in rates of imported cases, local outbreaks in non-endemic areas and the global spread of drug resistance. With elimination and global eradication back on the agenda, changing levels and compositions of imported malaria in malaria-free countries, and the threat of artemisinin resistance spreading from Southeast Asia, there is a need to better understand how the modern flow of air passengers connects each Plasmodium falciparum- and Plasmodium vivax-endemic region to the rest of the world. Recently constructed global P. falciparum and P.vivax malaria risk maps, along with data on flight schedules and modelled passenger flows across the air network, were combined to describe and quantify global malaria connectivity through air travel. Network analysis approaches were then utilized to describe and quantify the patterns that exist in passenger flows weighted by malaria prevalence. Finally, the connectivity within and to the Southeast Asia region where the threat of imported artemisinin resistance arising is highest, was examined to highlight risk routes for its spread. The analyses demonstrate the substantial connectivity that now exists between and from malaria-endemic regions through air travel. While the air network provides connections to previously isolated malarious regions, it is clear that great variations exist, with significant regional communities of airports connected by higher rates of flow standing out. The structures of these communities are often not geographically coherent, with historical, economic and cultural ties evident, and variations between P. falciparum and P. vivax clear. Moreover, results highlight how well connected the malaria-endemic areas of Africa are now to Southeast Asia, illustrating the many possible routes that artemisinin-resistant strains could take. The continuing growth in air travel is playing an important role in the

  1. Resting state functional connectivity in anorexia nervosa.

    Science.gov (United States)

    Phillipou, Andrea; Abel, Larry Allen; Castle, David Jonathan; Hughes, Matthew Edward; Nibbs, Richard Grant; Gurvich, Caroline; Rossell, Susan Lee

    2016-05-30

    Anorexia Nervosa (AN) is a serious psychiatric illness characterised by a disturbance in body image, a fear of weight gain and significantly low body weight. The factors involved in the genesis and maintenance of AN are unclear, though the potential neurobiological underpinnings of the condition are of increasing interest. Through the investigation of functional connectivity of the brain at rest, information relating to neuronal communication and integration of information that may relate to behaviours and cognitive symptoms can be explored. The aim of this study was to investigate functional connectivity of the default mode network, and sensorimotor and visual networks in AN. 26 females with AN and 27 healthy control participants matched for age, gender and premorbid intelligence underwent a resting state functional magnetic resonance imaging scan. Default mode network functional connectivity did not differ between groups. AN participants displayed reduced functional connectivity between the sensorimotor and visual networks, in comparison to healthy controls. This finding is discussed in terms of differences in visuospatial processing in AN and the distortion of body image experienced by these individuals. Overall, the findings suggest that sensorimotor and visual network connectivity may be related to visuospatial processing in AN, though, further research is required. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  2. Disrupted functional connectivity in adolescent obesity.

    Science.gov (United States)

    Moreno-Lopez, Laura; Contreras-Rodriguez, Oren; Soriano-Mas, Carles; Stamatakis, Emmanuel A; Verdejo-Garcia, Antonio

    2016-01-01

    Obesity has been associated with brain alterations characterised by poorer interaction between a hypersensitive reward system and a comparatively weaker prefrontal-cognitive control system. These alterations may occur as early as in adolescence, but this notion remains unclear, as no studies so far have examined global functional connectivity in adolescents with excess weight. We investigated functional connectivity in a sample of 60 adolescents with excess weight and 55 normal weight controls. We first identified parts of the brain displaying between-group global connectivity differences and then characterised the extent of the differences in functional network integrity and their association with reward sensitivity. Adolescent obesity was linked to neuroadaptations in functional connectivity within brain hubs linked to interoception (insula), emotional memory (middle temporal gyrus) and cognitive control (dorsolateral prefrontal cortex) (pFWE adolescent obesity is linked to disrupted functional connectivity in brain networks relevant to maintaining balance between reward, emotional memories and cognitive control. Our findings may contribute to reconceptualization of obesity as a multi-layered brain disorder leading to compromised motivation and control, and provide a biological account to target prevention strategies for adolescent obesity.

  3. Connection Facility Layout Model of Subway Stations

    Directory of Open Access Journals (Sweden)

    Liya Yao

    2015-01-01

    Full Text Available As the key node of public transportation system, subway station has many functions such as attracting and distributing passengers and guiding the transfer from various traffic modes to subway. However, the poor facility scale and layout around subway stations in practice usually cause the inconvenience of transfer and low transfer efficiency, which causes the declination of travel efficiency and even loose of subway passengers. Taking subway stations as the study objects, this paper has emphasis on the connection characters between various traffic modes and subway stations. Considering the attraction region, the total transfer time, transfer distance, and connection cost were selected to form the efficiency index of connection layout of subway stations. Data envelopment analysis (DEA model is applied in the quantization of traffic resource consumption and output. At last, connection facility layout model of subway stations was established with the aim of improving the transfer efficiency. Meaningful results were obtained from the connection layout model of subway stations, which guide the planning and designing of the transfer facilities around subway stations.

  4. CRRT Connected to ECMO: Managing High Pressures.

    Science.gov (United States)

    de Tymowski, Christian; Augustin, Pascal; Houissa, Hamda; Allou, Nicolas; Montravers, Philippe; Delzongle, Alienor; Pellenc, Quentin; Desmard, Mathieu

    Metabolic disorders and fluid overload are indications of continuous renal replacement therapy (CRRT) including continuous venovenous hemofiltration in patients on extracorporeal membrane oxygenation (ECMO). Direct connection of CRRT machine to the ECMO circuit provides many advantages. Nevertheless, because pressures in CRRT lines relate to ECMO blood flow, high ECMO blood flow may be associated with high pressures in CRRT lines. Thus, management of CRRT pressure lines becomes challenging. We evaluated a protocol for managing high CRRT pressures. Connections were performed according to a standardized protocol to maintain CRRT lines in the correct pressure ranges without modifying ECMO settings or inhibiting pressure alarms. To achieve this goal, the way of connecting of CRRT lines was adapted following a standardized protocol. Connection was first attempted between pump and oxygenator in the 12 patients. In five cases, high pressures in CRRT lines were successfully managed by changing the connection segment. Continuous renal replacement therapy parameters were within target levels and reduction of serum creatinine was 37%. In conclusion, management of high pressures in CRRT lines induced by ECMO could be achieved without modifying ECMO blood flow or inhibiting CRRT alarms. Iterative stops were avoided allowing efficient procedures.

  5. A systematic framework for functional connectivity measures

    Directory of Open Access Journals (Sweden)

    Huifang Elizabeth Wang

    2014-12-01

    Full Text Available Various methods have been proposed to characterize the functional connectivity between nodes in a network measured with different modalities (electrophysiology, functional magnetic resonance imaging etc.. Since different measures of functional connectivity yield different results for the same dataset, it is important to assess when and how they can be used. In this work, we provide a systematic framework for evaluating the performance of a large range of functional connectivity measures – based upon a comprehensive portfolio of models generating measurable responses. Specifically, we benchmarked 42 methods using 10,000 simulated datasets from 5 different types of generative models with different connectivity structures. Since all functional connectivity methods require the setting of some parameters (window size and number, model order etc., we first optimized these parameters using performance criteria based upon (threshold free ROC analysis. We then evaluated the performance of the methods on data simulated with different types of models. Finally, we assessed the performance of the methods against different levels of signal-to-noise ratios and network configurations. A MATLAB toolbox is provided to perform such analyses using other methods and simulated datasets.

  6. Connected Car: Quantified Self becomes Quantified Car

    Directory of Open Access Journals (Sweden)

    Melanie Swan

    2015-02-01

    Full Text Available The automotive industry could be facing a situation of profound change and opportunity in the coming decades. There are a number of influencing factors such as increasing urban and aging populations, self-driving cars, 3D parts printing, energy innovation, and new models of transportation service delivery (Zipcar, Uber. The connected car means that vehicles are now part of the connected world, continuously Internet-connected, generating and transmitting data, which on the one hand can be helpfully integrated into applications, like real-time traffic alerts broadcast to smartwatches, but also raises security and privacy concerns. This paper explores the automotive connected world, and describes five killer QS (Quantified Self-auto sensor applications that link quantified-self sensors (sensors that measure the personal biometrics of individuals like heart rate and automotive sensors (sensors that measure driver and passenger biometrics or quantitative automotive performance metrics like speed and braking activity. The applications are fatigue detection, real-time assistance for parking and accidents, anger management and stress reduction, keyless authentication and digital identity verification, and DIY diagnostics. These kinds of applications help to demonstrate the benefit of connected world data streams in the automotive industry and beyond where, more fundamentally for human progress, the automation of both physical and now cognitive tasks is underway.

  7. Connectivity: An emerging concept for physiotherapy practice.

    Science.gov (United States)

    Nicholls, David A; Atkinson, Karen; Bjorbækmo, Wenche S; Gibson, Barbara E; Latchem, Julie; Olesen, Jens; Ralls, Jenny; Setchell, Jennifer

    2016-01-01

    Having spent their first century anchored to a biomedical model of practice, physiotherapists have been increasingly interested in exploring new models and concepts that will better equip them for serving the health-care needs of 21st century clients/patients. Connectivity offers one such model. With an extensive philosophical background in phenomenology, symbolic interactionism, structuralism, and postmodern research, connectivity resists the prevailing western biomedical view that health professionals should aim to increase people's independence and autonomy, preferring instead to identify and amplify opportunities for collaboration and co-dependence. Connectivity critiques the normalization that underpins modern health care, arguing that our constant search for deviance is building stigma and discrimination into our everyday practice. It offers provocative opportunities for physiotherapists to rethink some of the fundamental tenets of their profession and better align physiotherapy with 21st century societal expectations. In this paper, we provide a background to the place connectivity may play in future health care, and most especially future physiotherapy practice. The paper examines some of the philosophical antecedents that have made connectivity an increasingly interesting and challenging concept in health care today.

  8. Randomness in resting state functional connectivity matrices.

    Science.gov (United States)

    Vergara, Victor M; Calhoun, Vince

    2016-08-01

    Separate brain regions exhibit synchronous intrinsic activity used to assess connectivity patterns known to appear among brain areas. Connectivity is evaluated from functional magnetic resonance imaging (fMRI) measuring the blood oxygen level dependent signal (BOLD) signal. Extensive research has revealed a distinctive pattern of connectivity among brain areas that can be visualized through a functional connectivity matrix (FCM) matrix. As in any measurement, BOLD signals are subject to contamination from noise and nuisances unrelated to brain's intrinsic activity. Up until now, little work has been developed to determine if patterns observed in FCMs occurred by chance or were driven by a more deterministic process. This work proposes a mathematical framework to test the randomness of FCM connectivity patterns in a systematic and statistical way. A cohort of 121 healthy controls is used to demonstrate the usefulness of the proposed framework. Results indicate that particular parts of the brain might exhibit decreasing randomness with age and gender. Results also show the framework's effectiveness in assessing FCM randomness.

  9. Political Connections and Investment in Rural Vietnam

    DEFF Research Database (Denmark)

    Markussen, Thomas; Tarp, Finn

    This paper uses household panel data from rural Vietnam to explore the effects of having a relative in a position of political or bureaucratic power on farmers’ agricultural investment decisions. Our main result is that households significantly increase their investment in land improvement...... as a result of relatives moving into public office. Connections to office holders appear to be important for investment because they strengthen de facto land property rights and improve access to off-farm employment and to informal loans. The findings underline the importance of informal networks for economic...... behaviour in environments with developing institutions and markets. They also suggest the presence of an untapped potential for economic development: if households without connections could obtain equally strong property rights and access to credit and insurance as the well-connected households, investment...

  10. Healthcare e-commerce: connecting with patients.

    Science.gov (United States)

    Joslyn, J S

    2001-01-01

    Electronically connecting with patients is a challenging frontier at which technical hurdles are probably exceeded by political, legal, and other barriers. The rise of consumerism, however, compels a response focused more on revenue and strategic advantage than on pure cost savings. Among the difficulties faced by providers is choosing among various models of connectivity and component function. Emerging models include "free-floating" personal medical records largely independent of the office-based physician, systems with compatible and intertwined physician and consumer relationships using an application services provider office practice system, and systems that connect patients and providers through e-mail, office triage, prescription refills, scheduling, and so on. This article discusses these and other combinations of technology that significantly overcome the barriers involved and that may be woven together to provide solutions uniquely suited to various competitive situations.

  11. Evolution Strategies in the Multipoint Connections Routing

    Directory of Open Access Journals (Sweden)

    L. Krulikovska

    2010-09-01

    Full Text Available Routing of multipoint connections plays an important role in final cost and quality of a found connection. New algorithms with better results are still searched. In this paper, a possibility of using the evolution strategies (ES for routing is presented. Quality of found connection is evaluated from the view of final cost and time spent on a searching procedure. First, parametrical analysis of results of the ES are discussed and compared with the Prim’s algorithm, which was chosen as a representative of the deterministic routing algorithms. Second, ways for improving the ES are suggested and implemented. The obtained results are reviewed. The main improvements are specified and discussed in conclusion.

  12. Quantifying Riverscape Connectivity with Graph Theory

    Science.gov (United States)

    Carbonneau, P.; Milledge, D.; Sinha, R.; Tandon, S. K.

    2013-12-01

    Fluvial catchments convey fluxes of water, sediment, nutrients and aquatic biota. At continental scales, crustal topography defines the overall path of channels whilst at local scales depositional and/or erosional features generally determine the exact path of a channel. Furthermore, constructions such as dams, for either water abstraction or hydropower, often have a significant impact on channel networks.The concept of ';connectivity' is commonly invoked when conceptualising the structure of a river network.This concept is easy to grasp but there have been uneven efforts across the environmental sciences to actually quantify connectivity. Currently there have only been a few studies reporting quantitative indices of connectivity in river sciences, notably, in the study of avulsion processes. However, the majority of current work describing some form of environmental connectivity in a quantitative manner is in the field of landscape ecology. Driven by the need to quantify habitat fragmentation, landscape ecologists have returned to graph theory. Within this formal setting, landscape ecologists have successfully developed a range of indices which can model connectivity loss. Such formal connectivity metrics are currently needed for a range of applications in fluvial sciences. One of the most urgent needs relates to dam construction. In the developed world, hydropower development has generally slowed and in many countries, dams are actually being removed. However, this is not the case in the developing world where hydropower is seen as a key element to low-emissions power-security. For example, several dam projects are envisaged in Himalayan catchments in the next 2 decades. This region is already under severe pressure from climate change and urbanisation, and a better understanding of the network fragmentation which can be expected in this system is urgently needed. In this paper, we apply and adapt connectivity metrics from landscape ecology. We then examine the

  13. A Model of Trusted Connection Architecture

    Directory of Open Access Journals (Sweden)

    Zhang Xun

    2017-01-01

    Full Text Available According to that traditional trusted network connection architecture (TNC has limitations on dynamic network environment and the user behavior support, we develop TCA to propose a trusted connection architecture supporting behavior measurement (TCA-SBM, besides, the structure diagram of network architecture is given. Through introducing user behavior measure elements, TCA-SBM can conduct measurement on the whole network in time dimension periodically, and refine the measurement on network behavior in measure dimension to conduct fine-grained dynamic trusted measurement. As a result, TCA-SBM enhances the TCA’s ability to adapt to the dynamic change of network and makes up the deficiency of trusted computing framework in the network connection.

  14. LR: Compact connectivity representation for triangle meshes

    Energy Technology Data Exchange (ETDEWEB)

    Gurung, T; Luffel, M; Lindstrom, P; Rossignac, J

    2011-01-28

    We propose LR (Laced Ring) - a simple data structure for representing the connectivity of manifold triangle meshes. LR provides the option to store on average either 1.08 references per triangle or 26.2 bits per triangle. Its construction, from an input mesh that supports constant-time adjacency queries, has linear space and time complexity, and involves ordering most vertices along a nearly-Hamiltonian cycle. LR is best suited for applications that process meshes with fixed connectivity, as any changes to the connectivity require the data structure to be rebuilt. We provide an implementation of the set of standard random-access, constant-time operators for traversing a mesh, and show that LR often saves both space and traversal time over competing representations.

  15. Connections between algebra, combinatorics, and geometry

    CERN Document Server

    Sather-Wagstaff, Sean

    2014-01-01

    Commutative algebra, combinatorics, and algebraic geometry are thriving areas of mathematical research with a rich history of interaction. Connections Between Algebra, Combinatorics, and Geometry contains lecture notes, along with exercises and solutions, from the Workshop on Connections Between Algebra and Geometry held at the University of Regina from May 29-June 1, 2012. It also contains research and survey papers from academics invited to participate in the companion Special Session on Interactions Between Algebraic Geometry and Commutative Algebra, which was part of the CMS Summer Meeting at the University of Regina held June 2–3, 2012, and the meeting Further Connections Between Algebra and Geometry, which was held at the North Dakota State University, February 23, 2013. This volume highlights three mini-courses in the areas of commutative algebra and algebraic geometry: differential graded commutative algebra, secant varieties, and fat points and symbolic powers. It will serve as a useful resou...

  16. Connections with nature and environmental behaviors.

    Science.gov (United States)

    Geng, Liuna; Xu, Jingke; Ye, Lijuan; Zhou, Wenjun; Zhou, Kexin

    2015-01-01

    The influence of environmental attitudes on environmental behaviors has long been discussed. However, few studies have addressed the foundation of such attitudes. In the present study, we explored primitive belief underlying environmental attitudes, i.e., connections with nature, and its relationship with pro-environmental behaviors. Specifically, we used scales, a computerized Implicit Association Test, and a situational simulation experiment to examine both explicit and implicit connections with nature, both deliberate and spontaneous environmental behaviors, and to find correlations between environmental connectedness and environmental behaviors. Results showed that explicit connectedness was positively correlated with deliberate environmental behaviors, while implicit connectedness was positively correlated with spontaneous environmental behaviors. Additionally, explicit and implicit connectedness was independent of each other. In conclusion, the current study confirms the positive role played by connections with nature in promoting environmental behavior, and accordingly suggests means to encourage pro-environmental behavior by enhancing people's connectedness to nature.

  17. Robust quantum optimizer with full connectivity.

    Science.gov (United States)

    Nigg, Simon E; Lörch, Niels; Tiwari, Rakesh P

    2017-04-01

    Quantum phenomena have the potential to speed up the solution of hard optimization problems. For example, quantum annealing, based on the quantum tunneling effect, has recently been shown to scale exponentially better with system size than classical simulated annealing. However, current realizations of quantum annealers with superconducting qubits face two major challenges. First, the connectivity between the qubits is limited, excluding many optimization problems from a direct implementation. Second, decoherence degrades the success probability of the optimization. We address both of these shortcomings and propose an architecture in which the qubits are robustly encoded in continuous variable degrees of freedom. By leveraging the phenomenon of flux quantization, all-to-all connectivity with sufficient tunability to implement many relevant optimization problems is obtained without overhead. Furthermore, we demonstrate the robustness of this architecture by simulating the optimal solution of a small instance of the nondeterministic polynomial-time hard (NP-hard) and fully connected number partitioning problem in the presence of dissipation.

  18. Kähler Quantization and Hitchin Connections

    DEFF Research Database (Denmark)

    Leth Gammelgaard, Niels

    In this thesis, we study geometric quantization as well as deformation quantization of symplectic manifolds endowed with a compatible complex structure. Using Karabegov's classification of star products with separation of variables, we give an explicit, local, combinatorial formula for any...... such deformation quantization, which uses Feynman graphs to encode the relevant differential operators. In particular, this yields an explicit formula for the Berezin-Toeplitz star product. For geometric quantization, we consider Andersen's generalization of Hitchin's projectively flat connection to a general...... symplectic manifold, and we extend his construction to geometric quantization with metaplectic correction. We calculate the curvature and prove that the connection is projectively flat if the symplectic manifold does not allow holomorphic vector fields. Furthermore, we prove that the Hitchin connection...

  19. Functional connectivity of emotional processing in depression.

    LENUS (Irish Health Repository)

    Carballedo, Angela

    2012-02-01

    OBJECTIVES: The aim of the study is to map a neural network of emotion processing and to identify differences in major depression compared to healthy controls. It is hypothesized that intentional perception of emotional faces activates connections between amygdala (Demir et al.), orbitofrontal cortex (OFC), anterior cingulate cortex (ACC) and prefrontal cortex (PFC) and that frontal-amygdala connections are altered in major depressive disorder (MDD). METHODS: Fifteen medication-free patients with MDD and fifteen healthy controls were enrolled. All subjects were assessed using the same face-matching functional Magnetic Resonance Imaging (fMRI) task, known to involve those areas. Brain activations were obtained using Statistical Parametric Mapping version 5 (SPM5) for data analysis and MARSBAR for extracting of fMRI time series. Then data was analyzed using structural equation modeling (SEM). RESULTS: A valid model was established for the left and the right hemispheres showing a circuit involving ACC, OFC, PFC and AMY. The left hemisphere shows significant lower connectivity strengths in patients than controls, for the pathway that goes from AMY to the OF11, and a trend of higher connectivity in patients for the path that goes from the PF9 to the OF11. In the right hemisphere, patients show lower connectivity coefficients in the paths from the AMY to OF11, from the AMY to ACC, and from the ACC to PF9. By the contrary, controls show lower connectivity strengths for the path that goes from ACC to AMY. CONCLUSIONS: Functional disconnection between limbic and frontal brain regions could be demonstrated using structural equation modeling. The interpretation of these findings could be that there is an emotional processing bias with disconnection bilaterally between amygdala to orbitofrontal cortices and in addition a right disconnection between amygdala and ACC as well as between ACC and prefrontal cortex possibly in line with a more prominent role for the right hemisphere

  20. Corticopontocerebellar Connectivity Disruption in Congenital Hemiplegia.

    Science.gov (United States)

    Fiori, Simona; Pannek, Kerstin; Pasquariello, Rosa; Ware, Robert S; Cioni, Giovanni; Rose, Stephen E; Boyd, Roslyn N; Guzzetta, Andrea

    2015-10-01

    Crossed cerebellar diaschisis is the disruption of functional connectivity between cerebrum and cerebellum after hemispheric unilateral brain lesions. In adults and to a lesser extent in children, crossed cerebellar diaschisis has been largely investigated by functional connectivity and demonstrated to influence paretic hand function. We aim to demonstrate a disruption in structural corticopontocerebellar (CPC) connectivity in children with congenital brain lesions and examine its correlation with paretic hand motor function. Thirty-six children (Manual Ability Classification System: I, n = 21; II, n = 15) with unilateral brain lesions and 18 controls were analyzed in a case-control study, and diffusion magnetic resonance imaging data were acquired at 3T. High angular resolution diffusion imaging probabilistic tractography was employed for the region of interest-based reconstruction of CPC tracts. To identify statistical differences in structural cerebrocerebellar connectivity between case and control groups, an asymmetry index based on the number of streamlines of CPC tracts was used. In the case group, the correlation between asymmetry index and hand function measures was also determined. Projections through the middle cerebellar peduncle to the contralateral cerebral cortex showed greater asymmetry in children with congenital unilateral brain lesion compared to controls (P = .03), thus indicating a disruption of structural cerebrocerebellar connectivity. The degree of asymmetry index showed a correlation (P < .03; r = -0.31) with impaired hand abilities in bimanual tasks. Disruption of structural cerebrocerebellar connectivity is present in patients with congenital unilateral brain injury and might be related to impaired hand function in bimanual skills, with potential implication in tailoring early intervention strategies. © The Author(s) 2015.

  1. Interregional differentiation of quality of life in Russia

    Directory of Open Access Journals (Sweden)

    Е. V. Vasilyeva

    2010-12-01

    Full Text Available Based on the developed methodological system for diagnostics of the quality of life in the region, major socio-economic challenges experienced by Federal Districts and RF Subjects have been analyzed. Considerable differentiation of quality of life in Russia and its influence on the socio-economic development of regions was considered.

  2. Application of virtual water trade theory in interregional grain ...

    African Journals Online (AJOL)

    China was partitioned into eight regions, and the virtual water flow due to regional grain allocation and transportation among these regions was calculated in 2008 based on virtual water and virtual water trade theories. Then, we analyzed the relations between virtual water trade structure and water resources utilization.

  3. 38 CFR 21.372 - Interregional transfer at government expense.

    Science.gov (United States)

    2010-07-01

    ... AFFAIRS (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Vocational Rehabilitation and Employment Under...-trainer when all necessary steps have been taken to establish an on-job training program; (4) To report to...: (i) There is no satisfactory opportunity for employment in the veteran's occupation within the...

  4. A dynamic model of interregional migration flows in Great Britain.

    Science.gov (United States)

    Molho, I

    1984-08-01

    "The purpose of this study is to construct a dynamic model of migration in Great Britain based on time-series data developed from the records of the National Health Service Center Register (NHSCR) on male migrants of working age between 1975 quarter 2 and 1979 quarter 2." A two-stage methodology "was developed...which differed in many important respects from the techniques adopted in previous studies of time-series migration flows. Regional push and pull factors were derived on the basis of the revealed preferences of migrants, using a two-stream gravity model, and then subsequently related to vectors of regional characteristics, within a general dynamic setting. Factors affecting the overall volume of migration nationally were separated out from those determining the internal direction of migration flows, and factors affecting distance sensitivity. Despite weaknesses in the available data set, the results achieved...suggested many interesting dynamic responses, implying lengthy and important lags in the estimated relationships." excerpt

  5. A review of variables of urban street connectivity for spatial connection

    Science.gov (United States)

    Mohamad, W. S. N. W.; Said, I.

    2014-02-01

    Several studies on street connectivity in cities and towns have been modeled on topology, morphology, technology and psychology of people living in the urban environment. Street connectivity means the connection of streets that offers people alternative routes. However, there emerge difficulties to determine the suitable variables and analysis to be chosen in defining the accurate result for studies street connectivity. The aim of this paper is to identify variables of street connectivity by applying GIS and Space Syntax. This paper reviews the variables of street connectivity from 15 past articles done in 1990s to early 2000s from journals of nine disciplines on Environment and Behavior, Planning and Design, Computers, Environment and Urban Systems, Applied Earth Observation and Geo-information, Environment and Planning, Physica A: Statistical Mechanics and its Applications, Environmental Psychology, Social Science and Medicine and Building and Environment. From the review, there are four variables found for street connectivity: link (streets-streets, street-nodes or node-streets, nodes-nodes), accessibility, least-angle, and centrality. Space syntax and GIS are suitable tools to analyze the four variables relating to systematic street systems for pedestrians. This review implies that planners of the street systems, in the aspect of street connectivity in cities and towns, should consider these four variables.

  6. Lymphoid neoplasia following connective tissue disease.

    Science.gov (United States)

    Banks, P M; Witrak, G A; Conn, D L

    1979-02-01

    A retrospective review was undertaken to ascertain whether there are distinctive histopathologic features of the lymphoid neoplasms that occur in patients with previous connective tissue disease. Of 29 patients studied, 12 had malignant lymphoma with diffuse large-cell cytomorphology. Only 1 of these 12 had an immunoblastic cell type. The remaining 17 patients had neoplasia of a widely diverse nature. Six had lymphocytic lymphoma (one nodular poorly differentiated, three diffuse poorly differentiated, and three diffuse well differentiated), two had Hodgkin's disease, three had plasma cell myeloma, and six had chronic lymphocytic leukemia. Data fail to confirm a relationship between lymphoid proliferations with immunoblastic morphology and connective tissue diseases.

  7. Differential geometry bundles, connections, metrics and curvature

    CERN Document Server

    Taubes, Clifford Henry

    2011-01-01

    Bundles, connections, metrics and curvature are the 'lingua franca' of modern differential geometry and theoretical physics. This book will supply a graduate student in mathematics or theoretical physics with the fundamentals of these objects. Many of the tools used in differential topology are introduced and the basic results about differentiable manifolds, smooth maps, differential forms, vector fields, Lie groups, and Grassmanians are all presented here. Other material covered includes the basic theorems about geodesics and Jacobi fields, the classification theorem for flat connections, the

  8. Cold electrical connection for FAIR/ SIS100

    CERN Document Server

    Kauschke, M; Quack, H

    2009-01-01

    The Facility of Antiproton and Ion Research (FAIR) will be an international centre for atomic-, plasma- and nuclear- physics, located next to Gesellschaft für Schwerionenforschung (GSI), Darmstadt. FAIR will be composed from two synchrotrons and four storage rings. Both synchrotrons, SIS100 and SIS300, are designed with superconducting magnets. For radiation protection reasons and landscaping restrictions the synchrotrons will be placed underground, whereas the power supplies will be placed within three service buildings above ground level. To save space and refrigeration power a superconducting electrical connection will be implemented. The mechanical and thermal design of this connection will be presented in the paper.

  9. A Grid-Connected Desalination Plant Operation

    Directory of Open Access Journals (Sweden)

    Won Ko

    2013-02-01

    Full Text Available In this paper, a grid-connected desalination plant operation approach is suggested. In desalination plant, large amount of energy is needed to operate pump and motor; hence most of energy is electricity. For this reason, the largest part of the operation cost is electricity charges. To demonstrate power usage, small size desalination measuring system mounted plant is used. Finally, to show the result of a grid-connected desalination plant operation, electric tariff rate of Korea is used. The result shows that total cost reduction rate is calculated about 1.6% of annual total electric plant operation cost.

  10. The Economics of Politically Connected Firms

    OpenAIRE

    CHOI, Jay Pil; Thum, Marcel

    2007-01-01

    Political connections between firms and autocratic regimes are not secret and often even publicly displayed in many developing economies. We argue that tying a firm’s available rent to a regime’s survival acts as a credible commitment forcing entrepreneurs to support the government and to exert effort in its stabilization. In return, politically connected firms get access to profitable markets and are exempted from the regime’s extortion. We show that such a gift exchange between govern...

  11. Multimodal Imaging Brain Connectivity Analysis (MIBCA toolbox

    Directory of Open Access Journals (Sweden)

    Andre Santos Ribeiro

    2015-07-01

    Full Text Available Aim. In recent years, connectivity studies using neuroimaging data have increased the understanding of the organization of large-scale structural and functional brain networks. However, data analysis is time consuming as rigorous procedures must be assured, from structuring data and pre-processing to modality specific data procedures. Until now, no single toolbox was able to perform such investigations on truly multimodal image data from beginning to end, including the combination of different connectivity analyses. Thus, we have developed the Multimodal Imaging Brain Connectivity Analysis (MIBCA toolbox with the goal of diminishing time waste in data processing and to allow an innovative and comprehensive approach to brain connectivity.Materials and Methods. The MIBCA toolbox is a fully automated all-in-one connectivity toolbox that offers pre-processing, connectivity and graph theoretical analyses of multimodal image data such as diffusion-weighted imaging, functional magnetic resonance imaging (fMRI and positron emission tomography (PET. It was developed in MATLAB environment and pipelines well-known neuroimaging softwares such as Freesurfer, SPM, FSL, and Diffusion Toolkit. It further implements routines for the construction of structural, functional and effective or combined connectivity matrices, as well as, routines for the extraction and calculation of imaging and graph-theory metrics, the latter using also functions from the Brain Connectivity Toolbox. Finally, the toolbox performs group statistical analysis and enables data visualization in the form of matrices, 3D brain graphs and connectograms. In this paper the MIBCA toolbox is presented by illustrating its capabilities using multimodal image data from a group of 35 healthy subjects (19–73 years old with volumetric T1-weighted, diffusion tensor imaging, and resting state fMRI data, and 10 subjets with 18F-Altanserin PET data also.Results. It was observed both a high inter

  12. Connected brains and minds--The UMCD repository for brain connectivity matrices.

    Science.gov (United States)

    Brown, Jesse A; Van Horn, John D

    2016-01-01

    We describe the USC Multimodal Connectivity Database (http://umcd.humanconnectomeproject.org), an interactive web-based platform for brain connectivity matrix sharing and analysis. The site enables users to download connectivity matrices shared by other users, upload matrices from their own published studies, or select a specific matrix and perform a real-time graph theory-based analysis and visualization of network properties. The data shared on the site span a broad spectrum of functional and structural brain connectivity information from humans across the entire age range (fetal to age 89), representing an array of different neuropsychiatric and neurodegenerative disease populations (autism spectrum disorder, ADHD, and APOE-4 carriers). An analysis combining 7 different datasets shared on the site illustrates the diversity of the data and the potential for yielding deeper insight by assessing new connectivity matrices with respect to population-wide network properties represented in the UMCD. Copyright © 2015 Elsevier Inc. All rights reserved.

  13. Cerebro-cerebellar connectivity is increased in primary lateral sclerosis.

    Science.gov (United States)

    Meoded, Avner; Morrissette, Arthur E; Katipally, Rohan; Schanz, Olivia; Gotts, Stephen J; Floeter, Mary Kay

    2015-01-01

    Increased functional connectivity in resting state networks was found in several studies of patients with motor neuron disorders, although diffusion tensor imaging studies consistently show loss of white matter integrity. To understand the relationship between structural connectivity and functional connectivity, we examined the structural connections between regions with altered functional connectivity in patients with primary lateral sclerosis (PLS), a long-lived motor neuron disease. Connectivity matrices were constructed from resting state fMRI in 16 PLS patients to identify areas of differing connectivity between patients and healthy controls. Probabilistic fiber tracking was used to examine structural connections between regions of differing connectivity. PLS patients had 12 regions with increased functional connectivity compared to controls, with a predominance of cerebro-cerebellar connections. Increased functional connectivity was strongest between the cerebellum and cortical motor areas and between the cerebellum and frontal and temporal cortex. Fiber tracking detected no difference in connections between regions with increased functional connectivity. We conclude that functional connectivity changes are not strongly based in structural connectivity. Increased functional connectivity may be caused by common inputs, or by reduced selectivity of cortical activation, which could result from loss of intracortical inhibition when cortical afferents are intact.

  14. Cerebro-cerebellar connectivity is increased in primary lateral sclerosis

    Directory of Open Access Journals (Sweden)

    Avner Meoded

    2015-01-01

    Full Text Available Increased functional connectivity in resting state networks was found in several studies of patients with motor neuron disorders, although diffusion tensor imaging studies consistently show loss of white matter integrity. To understand the relationship between structural connectivity and functional connectivity, we examined the structural connections between regions with altered functional connectivity in patients with primary lateral sclerosis (PLS, a long-lived motor neuron disease. Connectivity matrices were constructed from resting state fMRI in 16 PLS patients to identify areas of differing connectivity between patients and healthy controls. Probabilistic fiber tracking was used to examine structural connections between regions of differing connectivity. PLS patients had 12 regions with increased functional connectivity compared to controls, with a predominance of cerebro-cerebellar connections. Increased functional connectivity was strongest between the cerebellum and cortical motor areas and between the cerebellum and frontal and temporal cortex. Fiber tracking detected no difference in connections between regions with increased functional connectivity. We conclude that functional connectivity changes are not strongly based in structural connectivity. Increased functional connectivity may be caused by common inputs, or by reduced selectivity of cortical activation, which could result from loss of intracortical inhibition when cortical afferents are intact.

  15. Coupled Intrinsic Connectivity Distribution analysis: a method for exploratory connectivity analysis of paired FMRI data.

    Directory of Open Access Journals (Sweden)

    Dustin Scheinost

    Full Text Available We present a novel voxel-based connectivity approach for paired functional magnetic resonance imaging (fMRI data collected under two different conditions labeled the Coupled Intrinsic Connectivity Distribution (coupled-ICD. Our proposed method jointly models both conditions to incorporate additional paired information into the connectivity metric. Voxel-based connectivity holds promise as a clinical tool to characterize a wide range of neurological and psychiatric diseases, and monitor their treatment. As such, examining paired connectivity data such as scans acquired pre- and post-intervention is an important application for connectivity methodologically. When presented with data from paired conditions, conventional voxel-based methods analyze each condition separately. However, summarizing each connection separately can misrepresent patterns of changes in connectivity. We show that commonly used methods can underestimate functional changes and subsequently introduce and evaluate our solution to this problem, the coupled-ICD metric, using two studies: 1 healthy controls scanned awake and under anesthesia, and 2 cocaine-dependent subjects and healthy controls scanned while being presented with relaxing or drug-related imagery cues. The coupled-ICD approach detected differences between paired conditions in similar brain regions as the conventional approaches while also revealing additional changes in regions not identified using conventional voxel-based connectivity analyses. Follow-up seed-based analyses on data independent from the voxel-based results also showed connectivity differences between conditions in regions detected by coupled-ICD. This approach of jointly analyzing paired resting-state scans provides a new and important tool with many applications for clinical and basic neuroscience research.

  16. Battery impedance spectroscopy using bidirectional grid connected ...

    Indian Academy of Sciences (India)

    Shimul Kumar Dam

    Impedance spectroscopy; grid connection; battery converter; state of charge; health monitoring. 1. Introduction. Batteries play an important role as energy storage devices for renewable energy sources, electric vehicle and many other applications. A battery bank is interfaced to load through a power converter, which controls ...

  17. Multigenre Lab Reports: Connecting Literacy and Science

    Science.gov (United States)

    Rochwerger, Leonora; Peterson, Shelley Stagg; Calovini, Theresa

    2006-01-01

    The development of communication skills is a key component in any science program. However, students do not see the connections between writing and science. In particular, students lack the enthusiasm when the time comes to write lab reports. Students say that they do not see why they should have to write dry, boring lab reports following an…

  18. Emotional Connections in Higher Education Marketing

    Science.gov (United States)

    Durkin, Mark; McKenna, Seamas; Cummins, Darryl

    2012-01-01

    Purpose: Through examination of a case study this paper aims to describe a brand re-positioning exercise and explore how an emotionally driven approach to branding can help create meaningful connections with potential undergraduate students and can positively influence choice. Design/methodology/approach: The paper's approach is a case study…

  19. Connecting Reading and Writing: A Case Study

    Science.gov (United States)

    Li, Zhanfang

    2015-01-01

    Connecting reading and writing, proposed by many scholars, is realized in this case study. The 30 participants in this study are the English majors of the third year in one School of Foreign Languages in Beijing. They are encouraged to write journals every week, based on the source text materials in their Intensive Reading class, with the final…

  20. Privacy and Security in Connected Vehicles Ecosystems

    Directory of Open Access Journals (Sweden)

    Marius POPA

    2017-01-01

    Full Text Available Modern vehicles could not be figured out without Internet connections in order to provide customers a wide range of services in the vehicle: infotainment platforms, third-party support, on-board and online monitor and maintenance, business analytics for car fleets. Exposure of the vehicles to the Internet turns them into targets for viruses, worms, Trojans, DoS and lot of other threats for connected vehicle security. Beside the classic threats of the Internet exposure, other new threats are introduced by the Internet of Things (IoT new technologies that are poor regulated or undefined yet from the security point of view. Also, the large variety of the IoT technologies not being standardized yet contribute to security issues in this area of the automotive industry. This paper provides an overview of the connected vehicle environment, considering the main components of such kind of system and the main security challenges to be considered for building reliable secure online systems for connected vehicles.

  1. Connected Knowledge in Science and Mathematics Education

    Science.gov (United States)

    Zohar, Anat

    2006-01-01

    While the traditional meaning of connected knowledge is valuable in some school subjects, it does not address the main activities of knowledge acquisition in subjects such as physics and mathematics. The goal of this article is to analyze the relationships between the concepts "learning for understanding" and "connected…

  2. Quantized Abelian principle connections on Lorentzian manifolds

    Energy Technology Data Exchange (ETDEWEB)

    Benini, Marco [Pavia Univ. (Italy); Istituto Nazionale di Fisica Nucleare, Pavia (Italy); Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; Dappiaggi, Claudio [Pavia Univ. (Italy); Istituto Nazionale di Fisica Nucleare, Pavia (Italy); Schenkel, Alexander [Bergische Univ., Wuppertal (Germany). Fachgruppe Mathematik

    2013-03-15

    We construct a covariant functor from a category of Abelian principal bundles over globally hyperbolic spacetimes to a category of *-algebras that describes quantized principal connections. We work within an appropriate differential geometric setting by using the bundle of connections and we study the full gauge group, namely the group of vertical principal bundle automorphisms. Properties of our functor are investigated in detail and, similar to earlier works, it is found that due to topological obstructions the locality property of locally covariant quantum field theory is violated. Furthermore, we prove that, for Abelian structure groups containing a nontrivial compact factor, the gauge invariant Borchers- Uhlmann algebra of the vector dual of the bundle of connections is not separating on gauge equivalence classes of principal connections. We introduce a topological generalization of the concept of locally covariant quantum fields. As examples, we construct for the full subcategory of principal U(1)-bundles two natural transformations from singular homology functors to the quantum field theory functor that can be interpreted as the Euler class and the electric charge. In this case we also prove that the electric charges can be consistently set to zero, which yields another quantum field theory functor that satisfies all axioms of locally covariant quantum field theory.

  3. Connections between the matching and chromatic polynomials

    Directory of Open Access Journals (Sweden)

    E. J. Farrell

    1992-01-01

    Full Text Available The main results established are (i a connection between the matching and chromatic polynomials and (ii a formula for the matching polynomial of a general complement of a subgraph of a graph. Some deductions on matching and chromatic equivalence and uniqueness are made.

  4. Korean Kimchi Chemistry: A Multicultural Chemistry Connection

    Science.gov (United States)

    Murfin, Brian

    2009-01-01

    Connecting science with different cultures is one way to interest students in science, to relate science to their lives, and at the same time to broaden their horizons in a variety of ways. In the lesson described here, students make kimchi, a delicious and popular Korean dish that can be used to explore many important chemistry concepts,…

  5. Battery impedance spectroscopy using bidirectional grid connected ...

    Indian Academy of Sciences (India)

    Keywords. Impedance spectroscopy; grid connection; battery converter; state of charge; health monitoring ... impedance by frequency sweep, avoiding transients. The measured impedance has been compared to that from a commercially available impedance measurement equipment and is shown to have a good match.

  6. Connecting ICTs to Development: The IDRC Experience

    International Development Research Centre (IDRC) Digital Library (Canada)

    Software can now be written in local and indigenous languages – which poor people most often speak – making access to the Information Age available to them. ..... IDRC's early programming focused on supporting partners in a limited number of countries that were chosen because they had little or no connectivity ...

  7. Impact of autocorrelation on functional connectivity.

    Science.gov (United States)

    Arbabshirani, Mohammad R; Damaraju, Eswar; Phlypo, Ronald; Plis, Sergey; Allen, Elena; Ma, Sai; Mathalon, Daniel; Preda, Adrian; Vaidya, Jatin G; Adali, Tülay; Calhoun, Vince D

    2014-11-15

    Although the impact of serial correlation (autocorrelation) in residuals of general linear models for fMRI time-series has been studied extensively, the effect of autocorrelation on functional connectivity studies has been largely neglected until recently. Some recent studies based on results from economics have questioned the conventional estimation of functional connectivity and argue that not correcting for autocorrelation in fMRI time-series results in "spurious" correlation coefficients. In this paper, first we assess the effect of autocorrelation on Pearson correlation coefficient through theoretical approximation and simulation. Then we present this effect on real fMRI data. To our knowledge this is the first work comprehensively investigating the effect of autocorrelation on functional connectivity estimates. Our results show that although FC values are altered, even following correction for autocorrelation, results of hypothesis testing on FC values remain very similar to those before correction. In real data we show this is true for main effects and also for group difference testing between healthy controls and schizophrenia patients. We further discuss model order selection in the context of autoregressive processes, effects of frequency filtering and propose a preprocessing pipeline for connectivity studies. Copyright © 2014 Elsevier Inc. All rights reserved.

  8. Connecting biological concepts and religious behavior.

    Science.gov (United States)

    Beit-Hallahmi, Benjamin

    2012-04-01

    This commentary proposes experiments to examine connections between the presence of out-group members, neurovisceral reactions, religiosity, and ethnocentrism, to clarify the meaning of the correlational findings presented in the target article. It also suggests different ways of describing religious socialization and of viewing assertions about religion and health or about the human ability to detect pathogens.

  9. GOOSE: Semantic search on Internet connected sensors

    NARCIS (Netherlands)

    Schutte, K.; Bomhof, F.W.; Burghouts, G.J.; Diggelen, J. van; Hiemstra, P.; Hof, J. van 't; Kraaij, W.; Pasman, K.H.W.; Smith, A.J.E.; Versloot, C.A.; Wit, J.J. de

    2013-01-01

    More and more sensors are getting Internet connected. Examples are cameras on cell phones, CCTV cameras for traffic control as well as dedicated security and defense sensor systems. Due to the steadily increasing data volume, human exploitation of all this sensor data is impossible for effective

  10. Learning Connected Civics: Narratives, Practices, Infrastructures

    Science.gov (United States)

    Ito, Mizuko; Soep, Elisabeth; Kligler-Vilenchik, Neta; Shresthova, Sangita; Gamber-Thompson, Liana; Zimmerman, Arely

    2015-01-01

    Bringing together popular culture studies and sociocultural learning theory, in this paper we formulate the concept of "connected civics," grounded in the idea that young people today are engaging in new forms of politics that are profoundly participatory. Often working in collaboration with adult allies, they leverage digital media and…

  11. The Developmental Cognitive Neuroscience of Functional Connectivity

    Science.gov (United States)

    Stevens, Michael C.

    2009-01-01

    Developmental cognitive neuroscience is a rapidly growing field that examines the relationships between biological development and cognitive ability. In the past decade, there has been ongoing refinement of concepts and methodology related to the study of "functional connectivity" among distributed brain regions believed to underlie cognition and…

  12. Getting connected in Myanmar | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2016-09-23

    Sep 23, 2016 ... Myanmar encountered many challenges with respect to information and communications technology, but after years of falling behind, the country has made significant progress in digitally connecting with Asia and the rest of the world. This article is part of an ongoing series of stories about innovative ...

  13. Criminologyof the future: interdisciplinary scientific connections

    OpenAIRE

    Antonyan Yu.M.

    2014-01-01

    The results of interdisciplinary scientific connections of the modern criminology conditional on the open character of this science and the necessity of its further development are given. The narrow-purpose character of criminological researches is noted: trivial subject matter; the criminologists’ lack of psychological, psychiatric, economical, historical, biological, ethnological and other knowledge; insufficiency of complex interdisciplinary works and empirical studies. Different viewpoint...

  14. An Interoperable Security Framework for Connected Healthcare

    NARCIS (Netherlands)

    Asim, M.; Petkovic, M.; Qu, M.; Wang, C.

    2011-01-01

    Connected and interoperable healthcare system promises to reduce thecost of the healthcare delivery, increase its efficiency and enableconsumers to better engage with clinicians and manage their care. However at the same time it introduces new risks towards security andprivacy of personal health

  15. Connecting strangers at a train station

    DEFF Research Database (Denmark)

    Serafin, Stefania; Böttcher, Niels; Pellarin, Lars

    2005-01-01

    In this paper we describe a virtual instrument or a performance space, placed at Høje Tåstrup train station in Denmark, which is meant to establish communicative connections between strangers, by letting users of the system create soundscapes together across the rails. We discuss mapping...

  16. Simplified analysis of timber rivet connections

    Science.gov (United States)

    Douglas C. Stahl; Marshall. Begel; Ronald W. Wolfe

    2000-01-01

    Timber rivets, fasteners for glulam and heavy timber construction, have been used in Canada for about thirty years and recently were adopted by the U.S. National Design Specification for Wood Construction (NDS). Rivet connections can exhibit two failure modes, one of which is fundamentally different from those of other dowel fasteners. Failure can occur when a volume...

  17. Supervised hub-detection for brain connectivity

    Science.gov (United States)

    Kasenburg, Niklas; Liptrot, Matthew; Reislev, Nina Linde; Garde, Ellen; Nielsen, Mads; Feragen, Aasa

    2016-03-01

    A structural brain network consists of physical connections between brain regions. Brain network analysis aims to find features associated with a parameter of interest through supervised prediction models such as regression. Unsupervised preprocessing steps like clustering are often applied, but can smooth discriminative signals in the population, degrading predictive performance. We present a novel hub-detection optimized for supervised learning that both clusters network nodes based on population level variation in connectivity and also takes the learning problem into account. The found hubs are a low-dimensional representation of the network and are chosen based on predictive performance as features for a linear regression. We apply our method to the problem of finding age-related changes in structural connectivity. We compare our supervised hub-detection (SHD) to an unsupervised hub-detection and a linear regression using the original network connections as features. The results show that the SHD is able to retain regression performance, while still finding hubs that represent the underlying variation in the population. Although here we applied the SHD to brain networks, it can be applied to any network regression problem. Further development of the presented algorithm will be the extension to other predictive models such as classification or non-linear regression.

  18. Isolating USB connections in medical equipment.

    Science.gov (United States)

    Broeders, Jan-Hein

    2009-01-01

    Although offering several benefits, the universal serial bus (USB) port has not been rapidly adopted for connecting medical equipment. This is because it could affect safety procedures, with equipment not operating isolated from the mains. To overcome this, a single package isolation device has been developed that can be inserted directly into the USB signal path.

  19. Optical Fiber Connected VLBI Network in Japan

    Science.gov (United States)

    Kawaguchi Noriyuki 1, Kouno Yusuke 1, Suda Hiroshi 2, Takaba Hiroshi 3, Takashima Kazuhiro 4, Murata Yasuhiro 5

    Large radio telescopes located at the cenral area of Japan, Usuda 64m, Nobeyama 45m, Tsukuba 32m, Kashima 34m and Gifu 11m are connected with a high speed optical fiber communication network of 5-Gbps rate. We present the current state of the network configuration and observations.

  20. Parity and the spin–statistics connection

    Indian Academy of Sciences (India)

    A simple demonstration of the spin-statistics connection for general causal fields is obtained by using the parity operation to exchange spatial coordinates in the scalar product of a locally commuting field operator, evaluated at position x, with the same field operator evaluated at -x, at equal times.

  1. "Scars" connect classical and quantum theory

    CERN Multimedia

    Monteiro, T

    1990-01-01

    Chaotic systems are unstable and extremely sensitive to initial condititions. So far, scientists have been unable to demonstrate that the same kind of behaviour exists in quantum or microscopic systems. New connections have been discovered though between classical and quantum theory. One is the phenomena of 'scars' which cut through the wave function of a particle (1 page).

  2. Connectivity planning to address climate change

    Science.gov (United States)

    Tristan A. Nuñez; Joshua J. Lawler; Brad H. McRae; D. John Pierce; Meade B. Krosby; Darren M. Kavanagh; Peter H. Singleton; Joshua J. Tewksbury

    2013-01-01

    As the climate changes, human land use may impede species from tracking areas with suitable climates. Maintaining connectivity between areas of different temperatures could allow organisms to move along temperature gradients and allow species to continue to occupy the same temperature space as the climate warms. We used a coarse-filter approach to identify broad...

  3. "Leyendas" (Legends): Connecting Reading Cross-Culturally.

    Science.gov (United States)

    Ramos-Machail, Nancy; Leavell, Judy A.

    2000-01-01

    Describes how using the Hispanic tale "La Llorona" can help teachers connect cross-culturally with their students for enhanced literacy instruction. Describes ways "La Llorona" may be used in courses for preservice education majors and in elementary and middle-grade classes. Includes an annotated list of seven printed versions of "La Llorona." (SR)

  4. Connections up to homotopy and characteristic classes

    NARCIS (Netherlands)

    Crainic, M.

    2000-01-01

    The aim of this note is to clarify the relevance of \\connections up to homotopy" [4, 5] to the theory of characteristic classes, and to present an application to the characteristic classes of algebroids [3, 5, 7] (and of Poisson manifolds in particular [8, 13]). We have already remarked [4] that

  5. Connective Versus Collective Action in Social Movements

    DEFF Research Database (Denmark)

    Lundgaard, Daniel; Razmerita, Liana

    LivesMatter and the #IceBucketChallenge by analyzing Twitter and Facebook data from key periods of these movements,through a net nographic study. In particular, this study has investigated the following research questions: How are the logics of collective and connective action reflected in online social media interactions...

  6. Algebraic connection theory of L-modules

    NARCIS (Netherlands)

    Ruiter, Jan de

    1972-01-01

    It is striking that many contravariant algebraic aspects of manifolds and especially of connections and cunvature are not restricted to manifolds. Another question raised by the theory is the following one: how far are diffenentiable functions and differentiable fields on a differentiable manifold

  7. Robust Network Design - Connectivity and Beyond

    Science.gov (United States)

    2015-01-15

    data integrity part in subsections IIC, IID, IIE and IIF. II.A. RESOURCE EFFICIENT BACKBONE NETWORK DESIGN IN FAULT-FREE SCENARIO Prior to our...Optical Networks”, IEEE Transactions on Networking 25. S. Shirazipourazad, P. Ghosh and A. Sen, “On Connectivity of Airborne Networks” AIAA Journal of

  8. Headaches and Hormones: What's the Connection?

    Science.gov (United States)

    Headaches and hormones: What's the connection? Being female has some real health advantages, but not when it comes to headaches — particularly ... a relationship between headaches and hormonal changes. The hormones estrogen (ES-truh-jen) and progesterone (pro-JES- ...

  9. Assessing the Security of Connected Diabetes Devices.

    Science.gov (United States)

    Out, Dirk-Jan; Tettero, Olaf

    2017-03-01

    This article discusses the assessment of the (cyber)security of wirelessly connected diabetes devices under the DTSEC standard. We discuss the relation between diabetes devices and hackers, provide an overview of the DTSEC standard, and describe the process of security assessment of diabetes devices.

  10. Precentral gyrus functional connectivity signatures of autism

    Directory of Open Access Journals (Sweden)

    Mary Beth eNebel

    2014-05-01

    Full Text Available Motor impairments are prevalent in children with autism spectrum disorders (ASD and are perhaps the earliest symptoms to develop. In addition, motor skills relate to the communicative/social deficits at the core of ASD diagnosis, and these behavioral deficits may reflect abnormal connectivity within brain networks underlying motor control and learning. Despite the fact that motor abnormalities in ASD are well-characterized, there remains a fundamental disconnect between the complexity of the clinical presentation of ASD and the underlying neurobiological mechanisms. In this study, we examined connectivity within and between functional subregions of a key component of the motor control network, the precentral gyrus, using resting state functional Magnetic Resonance Imaging data collected from a large, heterogeneous sample of individuals with ASD as well as neurotypical controls. We found that the strength of connectivity within and between distinct functional subregions of the precentral gyrus was related to ASD diagnosis and to the severity of ASD traits. In particular, connectivity involving the dorsomedial (lower limb/trunk subregion was abnormal in ASD individuals as predicted by models using a dichotomous variable coding for the presence of ASD, as well as models using symptom severity ratings. These findings provide further support for a link between motor and social/communicative abilities in ASD.

  11. High capacity optical links for datacentre connectivity

    DEFF Research Database (Denmark)

    Tafur Monroy, Idelfonso; Usuga, Mario; Vegas Olmos, Juan José

    There is a timely and growing demand for high capacity optical data transport solutions to provide connectivity inside data centres and between data centres located at different geographical locations. The requirements for reach are in the order of 2 km for intra-datacentre and up to 100 km...

  12. Structurally-informed Bayesian functional connectivity analysis

    NARCIS (Netherlands)

    Hinne, M.; Ambrogioni, L.; Janssen, R.J.; Heskes, T.M.; Gerven, M.A.J. van

    2014-01-01

    Functional connectivity refers to covarying activity between spatially segregated brain regions and can be studied by measuring correlation between functional magnetic resonance imaging (fMRI) time series. These correlations can be caused either by direct communication via active axonal pathways or

  13. Renal involvement in autoimmune connective tissue diseases

    OpenAIRE

    Kronbichler, Andreas; Mayer, Gert

    2013-01-01

    Connective tissue diseases (CTDs) are a heterogeneous group of disorders that share certain clinical presentations and a disturbed immunoregulation, leading to autoantibody production. Subclinical or overt renal manifestations are frequently observed and complicate the clinical course of CTDs. Alterations of kidney function in Sj?gren syndrome, systemic scleroderma (SSc), auto-immune myopathies (dermatomyositis and polymyositis), systemic lupus erythematosus (SLE), antiphospholipid syndrome n...

  14. Offloading IP Flows onto Lambda-Connections

    NARCIS (Netherlands)

    Fioreze, Tiago; Oude Wolbers, Mattijs; van de Meent, R.; Pras, Aiko

    2007-01-01

    Optical networks are capable of switching IP traffic via lambda connections. In this way, big IP flows that overload the regular IP routing level may be moved to the optical level, where they get better Quality of Service (QoS). At the same time, the IP routing level is off-loaded and can serve

  15. Altered whole-brain connectivity in albinism.

    Science.gov (United States)

    Welton, Thomas; Ather, Sarim; Proudlock, Frank A; Gottlob, Irene; Dineen, Robert A

    2017-02-01

    Albinism is a group of congenital disorders of the melanin synthesis pathway. Multiple ocular, white matter and cortical abnormalities occur in albinism, including a greater decussation of nerve fibres at the optic chiasm, foveal hypoplasia and nystagmus. Despite this, visual perception is largely preserved. It was proposed that this may be attributable to reorganisation among cerebral networks, including an increased interhemispheric connectivity of the primary visual areas. A graph-theoretic model was applied to explore brain connectivity networks derived from resting-state functional and diffusion-tensor magnetic resonance imaging data in 23 people with albinism and 20 controls. They tested for group differences in connectivity between primary visual areas and in summary network organisation descriptors. Main findings were supplemented with analyses of control regions, brain volumes and white matter microstructure. Significant functional interhemispheric hyperconnectivity of the primary visual areas in the albinism group were found (P = 0.012). Tests of interhemispheric connectivity based on the diffusion-tensor data showed no significant group difference (P = 0.713). Second, it was found that a range of functional whole-brain network metrics were abnormal in people with albinism, including the clustering coefficient (P = 0.005), although this may have been driven partly by overall differences in connectivity, rather than reorganisation. Based on the results, it was suggested that changes occur in albinism at the whole-brain level, and not just within the visual processing pathways. It was proposed that their findings may reflect compensatory adaptations to increased chiasmic decussation, foveal hypoplasia and nystagmus. Hum Brain Mapp 38:740-752, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  16. Brain connectivity in pathological and pharmacological coma

    Directory of Open Access Journals (Sweden)

    Quentin Noirhomme

    2010-12-01

    Full Text Available Recent studies in patients with disorders of consciousness (DOC tend to support the view that awareness is not related to activity in a single brain region but to thalamo-cortical connectivity in the frontoparietal network. Functional neuroimaging studies have shown preserved albeit disconnected low level cortical activation in response to external stimulation in patients in a vegetative state or unresponsive wakefulness syndrome. While activation of these primary sensory cortices does not necessarily reflect conscious awareness, activation in higher order associative cortices in minimally conscious state patients seems to herald some residual perceptual awareness. PET studies have identified a metabolic dysfunction in a widespread fronto-parietal global neuronal workspace in DOC patients including the midline default mode network, ‘intrinsic’ system, and the lateral frontoparietal cortices or ‘extrinsic system’. Recent studies have investigated the relation of awareness to the functional connectivity within intrinsic and extrinsic networks, and with the thalami in both pathological and pharmacological coma. In brain damaged patients, connectivity in all default network areas was found to be non-linearly correlated with the degree of clinical consciousness impairment, ranging from healthy controls and locked-in syndrome to minimally conscious, vegetative, coma and brain dead patients. Anesthesia-induced loss of consciousness was also shown to correlate with a global decrease in cortico-cortical and thalamo-cortical connectivity in both intrinsic and extrinsic networks, but not in auditory or visual networks. In anesthesia, unconsciousness was also associated with a loss of cross-modal interactions between networks. These results suggest that conscious awareness critically depends on the functional integrity of thalamo-cortical and cortico-cortical frontoparietal connectivity within and between intrinsic and extrinsic brain networks.

  17. Altered functional and anatomical connectivity in schizophrenia.

    Science.gov (United States)

    Camchong, Jazmin; MacDonald, Angus W; Bell, Christopher; Mueller, Bryon A; Lim, Kelvin O

    2011-05-01

    Schizophrenia is characterized by a lack of integration between thought, emotion, and behavior. A disruption in the connectivity between brain processes may underlie this schism. Functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) were used to evaluate functional and anatomical brain connectivity in schizophrenia. In all, 29 chronic schizophrenia patients (11 females, age: mean=41.3, SD=9.28) and 29 controls (11 females, age: mean=41.1, SD=10.6) were recruited. Schizophrenia patients were assessed for severity of negative and positive symptoms and general cognitive abilities of attention/concentration and memory. Participants underwent a resting-fMRI scan and a DTI scan. For fMRI data, a hybrid independent components analysis was used to extract the group default mode network (DMN) and accompanying time-courses. Voxel-wise whole-brain multiple regressions with corresponding DMN time-courses was conducted for each subject. A t-test was conducted on resulting DMN correlation maps to look between-group differences. For DTI data, voxel-wise statistical analysis of the fractional anisotropy data was carried out to look for between-group differences. Voxel-wise correlations were conducted to investigate the relationship between brain connectivity and behavioral measures. Results revealed altered functional and anatomical connectivity in medial frontal and anterior cingulate gyri of schizophrenia patients. In addition, frontal connectivity in schizophrenia patients was positively associated with symptoms as well as with general cognitive ability measures. The present study shows convergent fMRI and DTI findings that are consistent with the disconnection hypothesis in schizophrenia, particularly in medial frontal regions, while adding some insight of the relationship between brain disconnectivity and behavior. © The Author 2009. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved.

  18. The connectivity of the basis graph of a branching greedoid

    NARCIS (Netherlands)

    Broersma, Haitze J.; Li, Xueliang; Li, Xueliang

    1992-01-01

    A result of Korte and Lovász states that the basis graph of every 2- connected greedoid is connected. We prove that the basis graph of every 3-connected branching greedoid is ( -- 1)-connected, where is the minimum in-degree (disregarding the root) of the underlying rooted directed (multi) graph. We

  19. Connect Global Positioning System RF Module

    Science.gov (United States)

    Franklin, Garth W.; Young, Lawrence E.; Ciminera, Michael A.; Tien, Jeffrey Y.; Gorelik, Jacob; Okihiro, Brian Bachman; Koelewyn, Cynthia L.

    2012-01-01

    The CoNNeCT Global Positioning System RF Module (GPSM) slice is part of the JPL CoNNeCT Software Defined Radio (SDR). CoNNeCT is the Communications, Navigation, and Net working reconfigurable Testbed project that is part of NASA's Space Communication and Nav igation (SCaN) Program. The CoNNeCT project is an experimental dem onstration that will lead to the advancement of SDRs and provide a path for new space communication and navigation systems for future NASA exploration missions. The JPL CoNNeCT SDR will be flying on the International Space Station (ISS) in 2012 in support of the SCaN CoNNeCT program. The GPSM is a radio-frequency sampler module (see Figure 1) that directly sub-harmonically samples the filtered GPS L-band signals at L1 (1575.42 MHz), L2 (1227.6 MHz), and L5 (1176.45 MHz). The JPL SDR receives GPS signals through a Dorne & Margolin antenna mounted onto a choke ring. The GPS signal is filtered against interference, amplified, split, and fed into three channels: L1, L2, and L5. In each of the L-band channels, there is a chain of bandpass filters and amplifiers, and the signal is fed through each of these channels to where the GPSM performs a one-bit analog-to-digital conversion (see Figure 2). The GPSM uses a sub-harmonic, single-bit L1, L2, and L5 sampler that samples at a clock rate of 38.656 MHz. The new capability is the down-conversion and sampling of the L5 signal when previous hardware did not provide this capability. The first GPS IIF Satellite was launched in 2010, providing the new L5 signal. With the JPL SDR flying on the ISS, it will be possible to demonstrate navigation solutions with 10-meter 3-D accuracy at 10-second intervals using a field-program mable gate array (FPGA)-based feedback loop running at 50 Hz. The GPS data bits will be decoded and used in the SDR. The GPSM will also allow other waveforms that are installed in the SDR to demonstrate various GNSS tracking techniques.

  20. Disturbed Interhemispheric Functional Connectivity Rather than Structural Connectivity in Irritable Bowel Syndrome

    Directory of Open Access Journals (Sweden)

    Rongfeng Qi

    2016-12-01

    Full Text Available Neuroimaging studies have demonstrated that irritable bowel syndrome (IBS—a relapsing functional bowel disorder—presents with disrupted brain connections. However, little is known about the alterations of interhemispheric functional connectivity and underlying structural connectivity in IBS. This study combined resting-state functional magnetic resonance imaging (MRI and diffusion tensor imaging (DTI to investigate changes in interhemispheric coordination in IBS patients. Resting-state functional and structural magnetic resonance images were acquired from 65 IBS patients and 67 healthy controls (matched for age, sex and educational level. Interhemispheric voxel-mirrored homotopic connectivity (VMHC was calculated and compared between groups. Homotopic regions showing abnormal VMHC in patients were targeted as regions of interest for analysis of DTI tractography. The fractional anisotropy, fiber number, and fiber length were compared between groups. Statistical analysis was also performed by including anxiety and depression as covariates to evaluate their effect. A Pearson correlation analysis between abnormal interhemispheric connectivity and clinical indices of IBS patients was performed. Compared to healthy controls, IBS patients had higher interhemispheric functional connectivity between bilateral thalami, cuneus, posterior cingulate cortices, lingual gyri and inferior occipital/cerebellum lobes, as well as lower interhemispheric functional connectivity between bilateral ventral anterior cingulate cortices (vACC and inferior parietal lobules (IPL. The inclusion of anxiety and depression as covariates abolished VMHC difference in vACC. Microstructural features of white matter tracts connecting functionally abnormal regions did not reveal any differences between the groups. VMHC values in vACC negatively correlated with the quality of life scores of patients. In conclusion, this study provides preliminary evidence of the disrupted

  1. BIOCOMPATIBILITY OF AZITROMICYN ON CONNECTIVE TISSUE

    Directory of Open Access Journals (Sweden)

    Shafira Kurnia

    2011-01-01

    Full Text Available Background: periodontal disease is commonly caused by bacteria, especially actinomyces actinomycetemcomitans and porphyromonas gingivalis have an abilty enter epithelial cells objectives: to investigate systemic azithromycin as the antibiotic of choice for periodontal disease based on biocomptability test in connective tissue. Material and Methods: BHK 21 cell lines were exposed to 0.025%, 0.050%, 0.075%, and 0.1% azithromycin solution for seven times. Samples were put in incubator for 24 hours. Result: Azitrromycin 0.050%-0.1% showed significant difference between life cells percentage and control, however, azithromycin 0.025% revealed insignificant difference with control. Conclusion: 0.025% azithromycin was considered biocompatible with connective tissue and 0.050% was not.

  2. FEMINISM AND COSMOPOLITANISM: SOME INEVITABLE CONNECTIONS

    Directory of Open Access Journals (Sweden)

    DIANA ELENA NEAGA

    2011-04-01

    Full Text Available In this paper I will approach the issue of feminism and cosmopolitanism in order to give arguments in sustaining the fact that, today, feminism and cosmopolitanism are inevitable connected. In constructing my discourse I will begin by laying out the main ideas of cosmopolitanism, followed by a presentation of the construction of the feminist movement over time, inter-relating these two discourses at the end of the analysis. Connected with political ethics, political theory and political philosophy, the theoretical framework selected for this paper is based on the cosmopolitan theory developed by scholars like Martha Nussbaum, Fiona Robinson and Kwame Anthony Appaih who, underlining universality, define cosmopolitism as a universal concern with every human life and its well-being, but who are also giving value to the differences (seen as cultural or/ and of identity insofar as they are not harmful to people.

  3. Sociology: a lost connection in social psychology.

    Science.gov (United States)

    Oishi, Shigehiro; Kesebir, Selin; Snyder, Benjamin H

    2009-11-01

    For the first half of the 20th century, sociology was one of the closest allies of social psychology. Over the past four decades, however, the connection with sociology has weakened, whereas new connections with neighboring disciplines (e.g., biology, economics, political science) have formed. Along the way, the sociological perspective has been largely lost in mainstream social psychology in the United States. Most social psychologists today are not concerned with collective phenomena and do not investigate social structural factors (e.g., residential mobility, socioeconomic status, dominant religion, political systems). Even when the social structural factors are included in the analysis, psychologists typically treat them as individual difference variables. Sociologist C. Wright Mills famously promoted sociological imagination, or the ability to see distal yet important social forces operating in a larger societal context. By comparing sociological perspectives to psychological perspectives, this article highlights the insights that the sociological perspective and sociological imagination can bring to social psychology.

  4. Connectivity editing for quad-dominant meshes

    KAUST Repository

    Peng, Chihan

    2013-08-01

    We propose a connectivity editing framework for quad-dominant meshes. In our framework, the user can edit the mesh connectivity to control the location, type, and number of irregular vertices (with more or fewer than four neighbors) and irregular faces (non-quads). We provide a theoretical analysis of the problem, discuss what edits are possible and impossible, and describe how to implement an editing framework that realizes all possible editing operations. In the results, we show example edits and illustrate the advantages and disadvantages of different strategies for quad-dominant mesh design. © 2013 The Author(s) Computer Graphics Forum © 2013 The Eurographics Association and John Wiley & Sons Ltd.

  5. Blade couple with dry friction connection

    Directory of Open Access Journals (Sweden)

    Půst L.

    2015-06-01

    Full Text Available Vibration of a blade couple damped by a dry friction contact in the shroud is investigated by means of hysteresis loops and response curves analysis. The studied system is excited by one harmonic external force in a frequency range near to the lowest eigenfrequency of real blades. Blades are connected by means of a damping element consisting of dry friction part linked in series with linear spring. This "stick-slip" damping element is supposed to be either weightless or of a very small mass which models the mass of elastically deformed parts of contacting bodies near the friction surface. Two approximate mathematical models of "stick-slip" dry friction elements are suggested and analysed. The response curves of blade couple connected by stick-slip damping element are presented for different values of slip friction forces and two values of mass of elastically deformed parts.

  6. Detecting connectivity changes in neuronal networks.

    Science.gov (United States)

    Berry, Tyrus; Hamilton, Franz; Peixoto, Nathalia; Sauer, Timothy

    2012-08-15

    We develop a method from semiparametric statistics (Cox, 1972) for the purpose of tracking links and connection strengths over time in a neuronal network from spike train data. We consider application of the method as implemented in Masud and Borisyuk (2011), and evaluate its use on data generated independently of the Cox model hypothesis, in particular from a spiking model of Izhikevich in four different dynamical regimes. Then, we show how the Cox method can be used to determine statistically significant changes in network connectivity over time. Our methodology is demonstrated using spike trains from multi-electrode array measurements of networks of cultured mammalian spinal cord cells. Copyright © 2012 Elsevier B.V. All rights reserved.

  7. Micro-generation network connection (renewables)

    Energy Technology Data Exchange (ETDEWEB)

    Thornycroft, J.; Russell, T.; Curran, J.

    2003-07-01

    The drive to reduce emissions of carbon dioxide will result in an increase in the number of small generation units seeking connection to the electric power distribution network. The objectives of this study were to consider connection issues relating to micro-generation from renewables and their integration into the UK distribution network. The document is divided into two sections. The first section describes the present system which includes input from micro-generation, the technical impacts and the financial considerations. The second part discusses technical, financial and governance options for the future. A summary of preferred options and recommendations is given. The study was carried out by the Halcrow Group Ltd under contract to the DTI.

  8. Advanced connection systems for architectural glazing

    CERN Document Server

    Afghani Khoraskani, Roham

    2015-01-01

    This book presents the findings of a detailed study to explore the behavior of architectural glazing systems during and after an earthquake and to develop design proposals that will mitigate or even eliminate the damage inflicted on these systems. The seismic behavior of common types of architectural glazing systems are investigated and causes of damage to each system, identified. Furthermore, depending on the geometrical and structural characteristics, the ultimate horizontal load capacity of glass curtain wall systems is defined based on the stability of the glass components. Detailed attention is devoted to the incorporation of advanced connection devices between the structure of the building and the building envelope system in order to minimize the damage to glazed components. An innovative new connection device is introduced that results in a delicate and functional system easily incorporated into different architectural glazing systems, including those demanding maximum transparency.

  9. Multipotent progenitor cells in gingival connective tissue.

    Science.gov (United States)

    Fournier, Benjamin P J; Ferre, François C; Couty, Ludovic; Lataillade, Jean-Jacques; Gourven, Murielle; Naveau, Adrien; Coulomb, Bernard; Lafont, Antoine; Gogly, Bruno

    2010-09-01

    The gum has an exceptional capacity for healing. To examine the basis for this property and explore the potential of conferring it to organs with inferior healing capacity, we sought the presence of progenitor cells in gingival connective tissue. Colony-forming units of fibroblast-enriched cells from gingival fibroblast cultures were assessed for expression of membrane markers of mesenchymal stem cells; capacity to differentiate into osteoblasts, chondroblasts, and adipocytes; and engraftment efficiency after in vivo transfer. On the basis of their ability to differentiate into several lineages, proliferate from single cells, induce calcium deposits, and secrete collagen in vivo after transfer on hydroxyapatite carriers, we suggest that this population represents gingival multipotent progenitor cells. The discovery of progenitor cells in gingival connective tissue may help improve our understanding of how the wounded gum is capable of almost perfect healing and opens the prospect of cellular therapy for wound healing using readily available cells at limited risk to the patient.

  10. Value Formation of Basic Anthropological Connectivities

    DEFF Research Database (Denmark)

    Bertelsen, Preben

    2009-01-01

    Abstract. Human beings live and thrive in surroundings based on the human condition of certain basic anthropological connectivities. Amongst the vital political life tasks can be mentioned the ones of establishing, maintaining and critically/conformably developing these basic conditions and their......Abstract. Human beings live and thrive in surroundings based on the human condition of certain basic anthropological connectivities. Amongst the vital political life tasks can be mentioned the ones of establishing, maintaining and critically/conformably developing these basic conditions...... and their political value formations. In this regard, the interdisciplinary contribution of Psychology is to explore how humans as active participants can and will participate in handling such value tasks. The article presents a general, theoretical, political-psychological model, which unites precisely these two...

  11. Mechanical connections between elastin and collagen.

    Science.gov (United States)

    Brown, R E; Butler, J P; Rogers, R A; Leith, D E

    1994-01-01

    The ligament supporting the leading edge of birds' wings is a connective tissue structure with unusual morphologic and elastic features. Its center section is made of a highly extensible composite of elastin and collagen fibers and its two end sections of nearly inextensible pure collagen; these are joined end-to-end in short interdigitating junctions. Substantial forces are transmitted through the junctions showing that collagen and elastin are mechanically connected. The junctions and elastic segment are sufficiently strong that when the intact ligament is maximally strained, the point of failure is commonly in the collagenous segments or their attachments to the tissues of origin or insertion. Here we outline the morphology and describe static force-length properties of this ligament.

  12. Nevos de tejido conectivo Connective tissue nevi

    Directory of Open Access Journals (Sweden)

    RE Achenbach

    Full Text Available Comunicamos dos casos de nevo del tejido conectivo, el primero con patrón histológico mixto y el segundo con predominio de alteraciones en las fibras elásticas. No se constataron síndromes ni patología sistémica asociada. Un caso presentó disposición linear y un nevo acrómico asociado.Two cases of connective tissue nevi are reported, one of them with a mixed histopatologic pattern and one with elastin fibers diminished. None of the patients had systemic involvement or associated syndromes. The mixed connective tissue nevi type showed a linear distribution and has associated an acromic nevi.

  13. Painful connections: densification versus fibrosis of fascia.

    Science.gov (United States)

    Pavan, Piero G; Stecco, Antonio; Stern, Robert; Stecco, Carla

    2014-01-01

    Deep fascia has long been considered a source of pain, secondary to nerve pain receptors becoming enmeshed within the pathological changes to which fascia are subject. Densification and fibrosis are among such changes. They can modify the mechanical properties of deep fasciae and damage the function of underlying muscles or organs. Distinguishing between these two different changes in fascia, and understanding the connective tissue matrix within fascia, together with the mechanical forces involved, will make it possible to assign more specific treatment modalities to relieve chronic pain syndromes. This review provides an overall description of deep fasciae and the mechanical properties in order to identify the various alterations that can lead to pain. Diet, exercise, and overuse syndromes are able to modify the viscosity of loose connective tissue within fascia, causing densification, an alteration that is easily reversible. Trauma, surgery, diabetes, and aging alter the fibrous layers of fasciae, leading to fascial fibrosis.

  14. Sentence structures with the connective verbs

    Directory of Open Access Journals (Sweden)

    Ružić Vladislava

    2006-01-01

    Full Text Available This paper talks about specific sentence structures in contemporary Serbian language that are a transition between simple and complex sentences, since they contain two finite forms of the verbs (e.g. To je da poludiš; Smisao pravde leži u tome da krivci budu kažnjeni, that however are a functionally - semantically unique predicate only when occurring together. At the position of the second part of the predicate phrase, there is a clause with a subordinate conjunction as its semantic core. Some types of the connective verbs are described, which have a specific role to connect subject argument and its related content or to mark the content of the sentence with a specific modality.

  15. Pure-Connection Gravity and Anisotropic Singularities

    Science.gov (United States)

    Krasnov, Kirill; Shtanov, Yuri

    2018-01-01

    In four space-time dimensions, there exists a special infinite-parameter family of chiral modified gravity theories. They are most properly described by a connection field, with space-time metric being a secondary and derived concept. All these theories have the same number of degrees of freedom as general relativity, which is the only parity-invariant member of this family. Modifications of general relativity can be arranged so as to become important in regions with large curvature. In this paper we review how a certain simple modification of this sort can resolve the Schwarzschild black-hole and Kasner anisotropic singularities of general relativity. In the corresponding solutions, the fundamental connection field is regular in space-time.

  16. Criticality and Connectivity in Macromolecular Charge Complexation

    Energy Technology Data Exchange (ETDEWEB)

    Qin, Jian; de Pablo, Juan J.

    2016-11-04

    We examine the role of molecular connectivity and architecture on the complexation of ionic macromolecules (polyelectrolytes) of finite size. A unified framework is developed and applied to evaluate the electrostatic correlation free energy for point-like, rod-like, and coil-like molecules. That framework is generalized to molecules of variable fractal dimensions, including dendrimers. Analytical expressions for the free energy, correlation length, and osmotic pressure are derived, thereby enabling consideration of the effects of charge connectivity, fractal dimension, and backbone stiffness on the complexation behavior of a wide range of polyelectrolytes. Results are presented for regions in the immediate vicinity of the critical region and far from it. A transparent and explicit expression for the coexistence curve is derived in order to facilitate analysis of experimentally observed phase diagrams.

  17. Connection Temperatures during the Mokrsko Fire Test

    Directory of Open Access Journals (Sweden)

    J. Chlouba

    2009-01-01

    Full Text Available The Mokrsko fire test focused on the overall behaviour of the structure, which cannot be observed on the separate elements, and also on the temperature of connections with improved fire resistance. During the test, measurements were made of the temperature of the gas and of the elements, the overall and relative deformations, gas pressure, humidity, the radiation of the compartment to structural element and the external steel column, transport of the moisture through the walls, and also the climatic conditions. The results of the test show the differences between the behaviour of the element and the behaviour of the structure exposed to high temperatures during a fire. The collapse of the composite slab was reached. The results of the numerical simulations using the SAFIR program compared well with the measured temperature values in the structure and also in the connections

  18. Hypersurfaces in simply connected space forms

    Indian Academy of Sciences (India)

    Statement of theorems. Let (M(κ), ds2) denote the simply connected space form of constant curvature κ = 0, 1 or −1 and dimension n + 1 ≥ 3. Let M be a hypersurface of (M(κ), ds2). For every point m ∈ M, let A: TmM → TmM be the Weingarten map of the hypersurface. In this paper we prove the following results. Theorem 1.

  19. Living Autoethnography: Connecting Life and Research

    OpenAIRE

    Faith Wambura Ngunjiri; Kathy-Ann C. Hernandez; Heewon Chang

    2010-01-01

    Autoethnography is a qualitative research method that utilizes data about self and context to gain an understanding of the connectivity between self and others. This introductory article exposes the reader to our own praxis of collaborative autoethnography which we used to interrogate how we navigate the US academy as immigrant women faculty. Before introducing the articles in this special issue, we explore the autoethnography continuum, provide sample areas covered by autoethnographers, and ...

  20. Connective tissue diseases mimicking multiple sclerosis

    OpenAIRE

    Maryam Moghaddassi-Jahromi; Mohammad-Ali Sahraian

    2011-01-01

    Background: Connective tissue diseases (CTD) can involve nervous system. Diagnosis and differentiation from multiple sclerosis (MS) can be difficult especially when the disease presented by symptoms and signs related to demyelinating process. The aim of this article is to review the variant forms of central nervous system involvement in CTD especially useful points for differentiation from demyelinating disorders. Materials and Method: We used the relevant articles in PUBMED, Scopus and other...

  1. [Diabetes and connected objects, appropriation or rejection?

    Science.gov (United States)

    Guillot, Caroline

    2017-11-01

    There are numerous connected objects aimed at the 3.5 million people with diabetes in France. What do patients think of them and what use do they actually get out of them? Diabète LAB, the living lab of the French Federation of Diabetics, questions patients with diabetes about their experiences, their uses of the technical devices and health services, as well as their needs. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  2. Incorporating seascape connectivity in conservation prioritisation

    Science.gov (United States)

    2017-01-01

    In conservation prioritisation, it is often implicit that representation targets for individual habitat types act as surrogates for the species that inhabit them. Yet for many commercially and ecologically important coral reef fish species, connectivity among different habitats in a seascape may be more important than any single habitat alone. Approaches to conservation prioritisation that consider seascape connectivity are thus warranted. I demonstrate an approach that can be implemented within a relatively data-poor context, using widely available conservation planning software. Based on clearly stated assumptions regarding species’ habitat usage and movement ability, this approach can be adapted to different focal species and contexts, or refined as further data become available. I first derive a seascape connectivity metric based on area-weighted proximity between juvenile and adult habitat patches, and then apply this during spatial prioritisation using the decision-support software Marxan. Using a case study from Micronesia, I present two applications: first, to inform prioritisation for a network of marine protected areas to achieve regional objectives for habitat representation; and second, to identify nursery habitat patches that are most likely to supply juveniles to adult populations on reefs within existing protected areas. Incorporating seascape connectivity in conservation prioritisation highlights areas where small marine protected areas placed on coral reefs might benefit from proximity to other habitats in the seascape, and thus be more effective. Within the context of community tenure over resources, identification of critical nursery habitats to improve the effectiveness of existing marine protected areas indicates where collaboration across community boundaries might be required. Outputs from these analyses are likely to be most useful in regions where management is highly decentralised, imposing spatial constraints on the size of individual

  3. EFFECT OF SEISMIC LOADING TO PREFABRICATED CONNECTIONS

    OpenAIRE

    Mizam DOĞAN; Hakan ÖZBAŞARAN; GÜNAYDIN, Ayten

    2010-01-01

    Most of industrial buildings are prefabricated structures and built on high seismic risk zones. Prefabricated buildings must be earthquake resistant which can be possible if structural elements and their connections are properly built. In recent years, prefabricated buildings which have no RC walls were damaged heavily during arthquakes. In this paper, prefabricated industrial structures, damaged during Ceyhan (1998), Kocaeli (1999) and Düzce (1999) earthquakes, and reasons of structural dama...

  4. Knowledge synthesis with maps of neural connectivity

    Directory of Open Access Journals (Sweden)

    Marcelo eTallis

    2011-11-01

    Full Text Available This paper describes software for neuroanatomical knowledge synthesis based on high-quality neural connectivity data. This software supports a mature neuroanatomical methodology developed since the early 1990s. Over this time, the Swanson laboratory at USC has generated an account of the neural connectivity of the sub-structures of the hypothalamus, amygdala, septum, hippocampus and bed nucleus of the stria terminalis. This is based on neuroanatomical data maps drawn into a standard brain atlas by experts. In earlier work, we presented an application for visualizing and comparing anatomical macroconnections using the Swanson 3rd edition atlas as a framework for accurate registration. Here we describe major improvements to the NeuARt application based on the incorporation of a knowledge representation of experimental design. We also present improvements in the interface and features of the neuroanatomical data mapping components within a unified web-application. As a step towards developing an accurate sub-regional account of neural connectivity, we provide navigational access between the neuroanatomical data maps and a semantic representation of area-to-area connections that they support. We do so based on an approach called ’Knowledge Engineering from Experimental Design’ (KEfED model that is based on experimental variables. We have extended the underlying KEfED representation of tract-tracing experiments by incorporating the definition of a neuronanatomical data map as a measurement variable in the study design. This paper describes the software design of a web application that allows anatomical data sets to be described within a standard experimental context and thus incorporated with non-spatial data sets.

  5. Detecting Cliques Using Degree and Connectivity Constraints

    OpenAIRE

    Abhay Avinash Bhamaikar; Pralhad Ramchandra Rao

    2012-01-01

    In graph mining determining clique is np complete problem. This paper introduces pruning strategies, by which linear time algorithm for detecting clique is obtained. Clique determination is widely applicable in social network analysis. In social network analysis cliques signifies that each person in the network knows every other person in the group. Here pruning is done using edge connectivity and degree constraints. Initially the graph (g) is checked for a bridge, if it is detected, then g...

  6. Prison Nursing: The Knowledge/Power Connection

    OpenAIRE

    ELIZABETH CLARE; LOUISE WALSH

    2009-01-01

    Prisons are institutions where power and control are complex issues which have a significant affect on nursing. This paper focuses on the development of a framework to illuminate an understanding of the way in which power, discourse and knowledge connect within the prison setting, and thus impact on both the emotional labour and professional practice of the prison nurse. Central to developing this framework is reference to a study which explored the emotional labour of prison nurses. In affec...

  7. Reduced Language Connectivity in Pediatric Epilepsy

    Science.gov (United States)

    Leigh N., Sepeta; Louise J., Croft; Lauren A., Zimmaro; Elizabeth S., Duke; Virginia K., Terwilliger; Benjamin E., Yerys; Xiaozhen., You; Chandan J., Vaidya; William D., Gaillard; Madison M., Berl

    2014-01-01

    Objective Functional connectivity (FC) among language regions is decreased in adults with epilepsy compared to controls, but less is known about FC in children with epilepsy. We sought to determine if language FC is reduced in pediatric epilepsy, and examined clinical factors that associate with language FC in this population. Methods We assessed FC during an age-adjusted language task in children with left-hemisphere focal epilepsy (n=19) compared to controls (n=19). Time series data were extracted for three left ROIs and their right homologues: inferior frontal gyrus (IFG), middle frontal gyrus (MFG), and Wernicke's area (WA) using SPM8. Associations between FC and factors such as cognitive performance, language dominance, and epilepsy duration were assessed. Results Children with epilepsy showed decreased interhemispheric connectivity compared to controls, particularly between core left language regions (IFG, WA) and their right hemisphere homologues, as well as decreased intrahemispheric right frontal FC. Increased intrahemispheric FC between left IFG and left WA was a positive predictor of language skills overall, and naming ability in particular. FC of language areas was not affected by language dominance, as the effects remained when only examining study participants with left language dominance. Overall FC did not differ according to duration of epilepsy or age of onset. Significance FC during a language task is reduced in children, similar to findings in adults. In specific, children with left focal epilepsy demonstrated decreased interhemispheric FC in temporal and frontal language connections and decreased intrahemispheric right frontal FC. These differences were present near the onset of epilepsy. Greater FC between left language centers is related to better language ability. Our results highlight that connectivity of language areas has a developmental pattern and is related to cognitive ability. PMID:25516399

  8. Emerging connections in the ethylene signaling network

    OpenAIRE

    Yoo, Sang-Dong; Cho, Younghee; Sheen, Jen

    2009-01-01

    The gaseous plant hormone ethylene acts as a pivotal mediator to respond to and coordinate internal and external cues in modulating plant growth dynamics and developmental programs. Genetic analysis of Arabidopsis thaliana has been used to identify key components and to build a linear ethylene-signaling pathway from the receptors through to the nuclear transcription factors. Studies applying integrative approaches have revealed new regulators, molecular connections and mechanisms in ethylene ...

  9. Perfiles Latinoamericanos: Regional sociology, connected sociologies

    Directory of Open Access Journals (Sweden)

    Nelson Arteaga Botello

    2017-07-01

    Full Text Available The landscape of sociology published in the 48 numbers of the Perfiles Latinoamericanos magazineis analyzed. The diversity of topics, perspectives, and methodologies of the articles define aseries of fields of reflection around civil society, collective action, subjectivities and social identities,cities, media, violence, and theory. The essay suggests how the sociology that is producedin Latin America is not isolated but connected with international debates. It converges forms ofdoing theory and research with resonances on a global scale.

  10. The Internet of things connecting objects

    CERN Document Server

    Chaouchi, Hakima

    2013-01-01

    Internet of Things: Connecting Objects… puts forward the technologies and the networking architectures which make it possible to support the Internet of Things. Amongst these technologies, RFID, sensor and PLC technologies are described and a clear view on how they enable the Internet of Things is given. This book also provides a good overview of the main issues facing the Internet of Things such as the issues of privacy and security, application and usage, and standardization.

  11. Supernovae and gamma-ray bursts connection

    Energy Technology Data Exchange (ETDEWEB)

    Valle, Massimo Della [INAF-Napoli, Capodimonte Observatory, Salita Moiariello, 16, I-80131 Napoli (Italy); International Center for Relativistic Astrophysics Network, Piazzale della Repubblica 10, I-65122, Pescara (Italy)

    2015-12-17

    I’ll review the status of the Supernova/Gamma-Ray Burst connection. Several pieces of evidence suggest that long duration Gamma-ray Bursts are associated with bright SNe-Ic. However recent works suggest that GRBs might be produced in tight binary systems composed of a massive carbon-oxygen cores and a neutron star companion. Current estimates of the SN and GRB rates yield a ratio GRB/SNe-Ibc in the range ∼ 0.4% − 3%.

  12. CONNECTION BETWEEN ANIMAL CRUELTY AND INTERPERSONAL VIOLENCE

    OpenAIRE

    Martina Horvat

    2011-01-01

    The article analyzes animal torture and other crimes and misdemeanors that sanction animal cruelty and torture. It displays the prevalence of violations of the provisions of Article 260 of the Croatian Penal Code. In addition it shows the current world researches that indicate a relationship between animal cruelty and violence among people in order to emphasize the connection between these seemingly different forms of violence and to explain the social danger of animal cruelty. Separately it ...

  13. Covered by lines and Conic connected varieties

    Directory of Open Access Journals (Sweden)

    Alex Massarenti

    2011-12-01

    Full Text Available We study some properties of an embedded variety covered by lines and give a numerical criterion ensuring the existence of a singular conic through two of its general points. We show that our criterion is sharp. Conic-connected, covered by lines, QEL, LQEL, prime Fano, defective, and dual defective varieties are closely related. We study some relations between the above mentioned classes of objects using basic results by Ein and Zak.

  14. Gender Differences in Brain Functional Connectivity Density

    OpenAIRE

    Tomasi, Dardo; Volkow, Nora D.

    2011-01-01

    The neural bases of gender differences in emotional, cognitive, and socials behaviors are largely unknown. Here, magnetic resonance imaging data from 336 women and 225 men revealed a gender dimorphism in the functional organization of the brain. Consistently across five research sites, women had 14% higher local functional connectivity density (lFCD) and up to 5% higher gray matter density than men in cortical and subcortical regions. The negative power scaling of the lFCD was steeper for men...

  15. Criminal law and psychology: Connection points

    OpenAIRE

    Drakić Dragiša

    2014-01-01

    In the paper the author discovers and analyzes areas which represent points of connection between criminal law and psychology, the areas in which cooperation between these two fields of science is possible and desirable. This article is divided into several sections. Firstly, the author talks about the emergence of psychology as a science and its definition. In the sections that follow the author offers analysis of initial contact between ways of thinking in primeval criminal law and psycholo...

  16. Careers, Connections and Corruption Risks in Europe

    DEFF Research Database (Denmark)

    Charron, Nicholas; Dahlström, Carl; Fazekas, Mihály

    the interplay between politics and bureaucracy. It suggests that corruption risks are minimized when the two groups involved in decision-making on public contracts—politicians and bureau-crats—have known different interests. This is institutionalized when politicians are accountable to the electorate, while.......4 million procurement contracts. Both show a remarkable sub-national variation across Europe. The study finds corruption risks significantly lower where bureau-crats’ careers do not depend on political connections....

  17. Adopting Energy Efficiency in Connected Homes

    Energy Technology Data Exchange (ETDEWEB)

    Christensen, Dane T [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Kemper, Emily [CLEAResult

    2017-10-02

    This presentation on connected homes was presented at the 11th Rocky Mountain Utility Efficiency Exchange on September 28, 2017. The discussion covered the integration of energy efficiency measures and practices with Internet of Things (IoT) awareness and adoption of smart technologies and services via WiFi/ Bluetooth enabled home and office equipment. The presentation also describes the benefits to the home and business and benefits/challenges for the utility/implementer.

  18. Mission Connect Mild TBI Translational Research Consortium

    Science.gov (United States)

    2010-08-31

    Mizrahi , MD – PI D. Frost, MD D. Friedman, MD R. Hrachovy, M.D J. Slater, MD Project Summary Introduction: This report outlines the participation...of Eli M. Mizrahi , M.D. and his colleagues in the Mission Connect Mild Traumatic Brain Injury (MTBI) Translational Research Consortium during the...time period of August 1, 2009 through July 31, 2010. Dr. Mizrahi is the principal investigator (P.I.) for the Neurophysiology Core which supports the

  19. The effect of connectives on the selection of arguments: implicit consequentiality bias for the connective "but".

    Science.gov (United States)

    Rigalleau, François; Guerry, Michèle; Granjon, Lionel

    2014-08-01

    Recent studies about the implicit causality of inter-personal verbs showed a symmetric implicit consequentiality bias for psychological verbs. This symmetry is less clear for action verbs because the verbs assigning the implicit cause to the object argument (e.g. "Peter protected John because he was in danger.") tend to assign the implicit consequence to the same argument (e.g. "Peter protected John so he was not hurt."). We replicated this result by comparing continuations of inter-personal events followed by a causal connective "because" or a consequence connective "so". Moreover, we found similar results when the consequence connective was replaced by a contrastive connective "but". This result was confirmed in a second experiment where we measured the time required to imagine a consistent continuation for a fragment finishing with "but s/he ...". The results were consistent with a contrastive connective introducing a denial of a consequence of the previous event. The results were consistent with a model suggesting that thematic roles and connectives can predict preferred co-reference relations.

  20. Transnational connections of later-life migrants.

    Science.gov (United States)

    Heikkinen, Sari Johanna; Lumme-Sandt, Kirsi

    2013-04-01

    In this paper a transnational perspective is used to explain whether and how older migrants construct and sustain their social networks. The paper uses a transnational viewpoint on older migrants' lives by analysing their engagement with their former homeland, and the intensity and habitualness of those engagements in old age. The aim of this article is to study the transnational connections of later-life migrants'. Attention is especially paid to the features of old age while maintaining these connections. These considerations are based on analyses of transnational networks in the everyday lives of later-life migrants from the former Soviet Union residing in Finland. The data were collected from 11 later-life migrants. It is found that transnational relationships are a vital part of the everyday lives of older migrants, and that they are sustained in varied ways. These connections mean a concrete source of help, family affiliations, the sharing of emotions, and a larger social network. Economic limitations affect the frequency and type of communication, and various physical limitations may also cause inability to maintain contacts across borders. In these circumstances, family members or other close relatives or friends are needed to deliver messages on the older person's behalf. Old age and immigration status affect the amount and direction of communication across borders, thereby shaping these networks. Copyright © 2013 Elsevier Inc. All rights reserved.

  1. Connection Cryostats for LHC Dispersion Suppressors

    CERN Document Server

    Marque, S; Genet, M; Skoczen, B

    2004-01-01

    The lattice of the Large Hadron Collider (LHC) being built at CERN is based on 8 standard arcs of 2.5 km length. Each arc is bounded on either side by Dispersion Suppressors connected to the arc by connection cryostats providing 15m long drift spaces. As for a dipole magnet, the connection cryostat provides a continuity of beam and insulation vacuum, electrical powering, cryogenic circuits, thermal and radiation shielding. In total 16 modules will be constructed. The stringent functional specification has led to various design options. Among them, a light mechanical structure has been developed with a stiffness comparable to that of a dipole magnet, for alignment purpose. Thermal studies, including lambda front propagation, have been performed to ensure a cooling down time to 1.9 K within the time budget. A special cooling scheme around the beam tubes has been chosen to cope with heat loads produced during operation. We report on the general design of these modules and on the adopted manufacturing process whi...

  2. Supervised hub-detection for brain connectivity

    DEFF Research Database (Denmark)

    Kasenburg, Niklas; Liptrot, Matthew George; Reislev, Nina Linde

    2016-01-01

    A structural brain network consists of physical connections between brain regions. Brain network analysis aims to find features associated with a parameter of interest through supervised prediction models such as regression. Unsupervised preprocessing steps like clustering are often applied, but ...... network regression problem. Further development of the presented algorithm will be the extension to other predictive models such as classification or non-linear regression....... hubs are a low-dimensional representation of the network and are chosen based on predictive performance as features for a linear regression. We apply our method to the problem of finding age-related changes in structural connectivity. We compare our supervised hub-detection (SHD) to an unsupervised hub......-detection and a linear regression using the original network connections as features. The results show that the SHD is able to retain regression performance, while still finding hubs that represent the underlying variation in the population. Although here we applied the SHD to brain networks, it can be applied to any...

  3. STRETCHING IMPACTS INFLAMMATION RESOLUTION IN CONNECTIVE TISSUE

    Science.gov (United States)

    Berrueta, Lisbeth; Muskaj, Igla; Olenich, Sara; Butler, Taylor; Badger, Gary J.; Colas, Romain A.; Spite, Matthew; Serhan, Charles N.; Langevin, Helene M.

    2016-01-01

    Acute inflammation is accompanied from its outset by the release of specialized pro-resolving mediators (SPMs), including resolvins, that orchestrate the resolution of local inflammation. We showed earlier that, in rats with subcutaneous inflammation of the back induced by carrageenan, stretching for 10 minutes twice daily reduced inflammation and improved pain, two weeks after carrageenan injection. In this study, we hypothesized that stretching of connective tissue activates local pro-resolving mechanisms within the tissue in the acute phase of inflammation. In rats injected with carrageenan and randomized to stretch vs. no stretch for 48 hours, stretching reduced inflammatory lesion thickness and neutrophil count, and increased resolvin (RvD1) concentrations within lesions. Furthermore, subcutaneous resolvin injection mimicked the effect of stretching. In ex vivo experiments, stretching of connective tissue reduced the migration of neutrophils and increased tissue RvD1 concentration. These results demonstrate a direct mechanical impact of stretching on inflammation-regulation mechanisms within connective tissue. PMID:26588184

  4. Synchronization and survival of connected bacterial populations

    Science.gov (United States)

    Gokhale, Shreyas; Conwill, Arolyn; Ranjan, Tanvi; Gore, Jeff

    Migration plays a vital role in controlling population dynamics of species occupying distinct habitat patches. While local populations are vulnerable to extinction due to demographic or environmental stochasticity, migration from neighboring habitat patches can rescue these populations through colonization of uninhabited regions. However, a large migratory flux can synchronize the population dynamics in connected patches, thereby enhancing the risk of global extinction during periods of depression in population size. Here, we investigate this trade-off between local rescue and global extinction experimentally using laboratory populations of E. coli bacteria. Our model system consists of co-cultures of ampicillin resistant and chloramphenicol resistant strains that form a cross-protection mutualism and exhibit period-3 oscillations in the relative population density in the presence of both antibiotics. We quantify the onset of synchronization of oscillations in a pair of co-cultures connected by migration and demonstrate that period-3 oscillations can be disturbed for moderate rates of migration. These features are consistent with simulations of a mechanistic model of antibiotic deactivation in our system. The simulations further predict that the probability of survival of connected populations in high concentrations of antibiotics is maximized at intermediate migration rates. We verify this prediction experimentally and show that survival is enhanced through a combination of disturbance of period-3 oscillations and stochastic re-colonization events.

  5. Exploring brain function from anatomical connectivity

    Directory of Open Access Journals (Sweden)

    Gorka eZamora-López

    2011-06-01

    Full Text Available The intrinsic relationship between the architecture of the brain and the range of sensory and behavioral phenomena it produces is a relevant question in neuroscience. Here, we review recent knowledge gained on the architecture of the anatomical connectivity by means of complex network analysis. It has been found that corticocortical networks display a few prominent characteristics: (i modular organization, (ii abundant alternative processing paths and (iii the presence of highly connected hubs. Additionally, we present a novel classification of cortical areas of the cat according to the role they play in multisensory connectivity. All these properties represent an ideal anatomical substrate supporting rich dynamical behaviors, as-well-as facilitating the capacity of the brain to process sensory information of different modalities segregated and to integrate them towards a comprehensive perception of the real world. The result here exposed are mainly based in anatomical data of cats’ brain, but we show how further observations suggest that, from worms to humans, the nervous system of all animals might share fundamental principles of organization.

  6. Criminologyof the future: interdisciplinary scientific connections

    Directory of Open Access Journals (Sweden)

    Antonyan Yu.M.

    2014-12-01

    Full Text Available The results of interdisciplinary scientific connections of the modern criminology conditional on the open character of this science and the necessity of its further development are given. The narrow-purpose character of criminological researches is noted: trivial subject matter; the criminologists’ lack of psychological, psychiatric, economical, historical, biological, ethnological and other knowledge; insufficiency of complex interdisciplinary works and empirical studies. Different viewpoints on the type of criminologists’ education are analyzed. That emphasizes the necessity of cooperation between criminology and other sciences, such as: sociology, demography, culturology, psychology, economics, pedagogics, psychiatry, ethnology, history, biology, political science, philosophy and others. The phenomenon of criminology is argued: it studies a “bad”, criminal, immoral person unlike other sciences (it belongs to the number of sciences which object is person. The main parameter of criminology as a science is examined – its subject which allows to distinguish it from other legal disciplines especially from criminal law. New aspects of interconnection between criminology and criminal procedure, criminalistics, the theory of investigation activity and criminal executive law are shown. The stable connections with family law, banking law, financial law and administrative law are considered. The author emphasizes the significant potential of developing criminology in its connection with nonlegal sciences: sociology, psychiatry, economics, statistics, psychology (including criminal psychology, biology and philosophy. It is noted that prospects and progress of criminology are possible only in its cooperation with other sciences.

  7. Connected formulas for amplitudes in standard model

    Energy Technology Data Exchange (ETDEWEB)

    He, Song [CAS Key Laboratory of Theoretical Physics,Institute of Theoretical Physics, Chinese Academy of Sciences,Beijing 100190 (China); School of Physical Sciences, University of Chinese Academy of Sciences,No. 19A Yuquan Road, Beijing 100049 (China); Zhang, Yong [Department of Physics, Beijing Normal University,Beijing 100875 (China); CAS Key Laboratory of Theoretical Physics,Institute of Theoretical Physics, Chinese Academy of Sciences,Beijing 100190 (China)

    2017-03-17

    Witten’s twistor string theory has led to new representations of S-matrix in massless QFT as a single object, including Cachazo-He-Yuan formulas in general and connected formulas in four dimensions. As a first step towards more realistic processes of the standard model, we extend the construction to QCD tree amplitudes with massless quarks and those with a Higgs boson. For both cases, we find connected formulas in four dimensions for all multiplicities which are very similar to the one for Yang-Mills amplitudes. The formula for quark-gluon color-ordered amplitudes differs from the pure-gluon case only by a Jacobian factor that depends on flavors and orderings of the quarks. In the formula for Higgs plus multi-parton amplitudes, the massive Higgs boson is effectively described by two additional massless legs which do not appear in the Parke-Taylor factor. The latter also represents the first twistor-string/connected formula for form factors.

  8. Modeling vertical coral connectivity and mesophotic refugia

    Science.gov (United States)

    Holstein, Daniel M.; Paris, Claire B.; Vaz, Ana C.; Smith, Tyler B.

    2016-03-01

    Whether mesophotic reefs will behave as refugia for corals threatened by global climate change and coastal development depends on vertical exchange of larvae between diverse habitats. Here we use a biophysical model of larval dispersal to estimate vertical connectivity of a broadcasting ( Orbicella faveolata) and a brooding ( Porites astreoides) species of coral in the US Virgin Islands. Modeling predicts subsidy to shallow areas by mesophotic larvae of both species based on local hydrology, adult reproductive characteristics, larval traits, and a wide range of scenarios developed to test depth-sensitive factors, such as fertilization rates and post-settlement survivorship. In extreme model scenarios of reduced fertilization and post-settlement survivorship of mesophotic larvae, 1-10 % local mesophotic subsidy to shallow recruitment is predicted for both species, which are demographically significant. Although direct vertical connectivity is higher for the broadcaster, the brooder demonstrates higher local multigenerational vertical connectivity, which suggests that local P. astreoides populations are more resilient than those of O. faveolata, and corroborates field studies. As shallow habitat degrades, mesophotic-shallow subsidy is predicted to increase for both species. This study is the first of its kind to simulate larval dispersal and settlement between habitats of different depths, and these findings have local, regional, and global implications for predicting and managing coral reef persistence in a changing climate.

  9. Zinc oxide: Connecting theory and experiment

    Directory of Open Access Journals (Sweden)

    Dejan Zagorac

    2013-09-01

    Full Text Available Zinc oxide (ZnO is a material with a great variety of industrial applications including high heat capacity, thermal conductivity and temperature stability. Clearly, it would be of great importance to find new stable and/or metastable modifications of zinc oxide, and investigate the influence of pressure and/or temperature on these structures, and try to connect theoretical results to experimental observations. In order to reach this goal, we performed several research studies, using modern theoretical methods. We have predicted possible crystal structures for ZnO using simulated annealing (SA, followed by investigations of the barrier structure using the threshold algorithm (TA. Finally, we have performed calculations using the prescribed path algorithm (PP, where connections between experimental structures on the energy landscape, and in particular transition states, were investigated in detail. The results were in good agreement with previous theoretical and experimental observations, where available, and we have found several additional (metastable modifications at standard, elevated and negative pressures. Furthermore, we were able to gain new insight into synthesis conditions for the various ZnO modifications and to connect our results to the actual synthesis and transformation routes.

  10. Orientations of infinite graphs with prescribed edge-connectivity

    DEFF Research Database (Denmark)

    Thomassen, Carsten

    2016-01-01

    We prove a decomposition result for locally finite graphs which can be used to extend results on edge-connectivity from finite to infinite graphs. It implies that every 4k-edge-connected graph G contains an immersion of some finite 2k-edge-connected Eulerian graph containing any prescribed vertex...... set (while planar graphs show that G need not containa subdivision of a simple finite graph of large edge-connectivity). Also, every 8k-edge connected infinite graph has a k-arc-connected orientation, as conjectured in 1989....

  11. Dynamic brain connectivity is a better predictor of PTSD than static connectivity.

    Science.gov (United States)

    Jin, Changfeng; Jia, Hao; Lanka, Pradyumna; Rangaprakash, D; Li, Lingjiang; Liu, Tianming; Hu, Xiaoping; Deshpande, Gopikrishna

    2017-09-01

    Using resting-state functional magnetic resonance imaging, we test the hypothesis that subjects with post-traumatic stress disorder (PTSD) are characterized by reduced temporal variability of brain connectivity compared to matched healthy controls. Specifically, we test whether PTSD is characterized by elevated static connectivity, coupled with decreased temporal variability of those connections, with the latter providing greater sensitivity toward the pathology than the former. Static functional connectivity (FC; nondirectional zero-lag correlation) and static effective connectivity (EC; directional time-lagged relationships) were obtained over the entire brain using conventional models. Dynamic FC and dynamic EC were estimated by letting the conventional models to vary as a function of time. Statistical separation and discriminability of these metrics between the groups and their ability to accurately predict the diagnostic label of a novel subject were ascertained using separate support vector machine classifiers. Our findings support our hypothesis that PTSD subjects have stronger static connectivity, but reduced temporal variability of connectivity. Further, machine learning classification accuracy obtained with dynamic FC and dynamic EC was significantly higher than that obtained with static FC and static EC, respectively. Furthermore, results also indicate that the ease with which brain regions engage or disengage with other regions may be more sensitive to underlying pathology than the strength with which they are engaged. Future studies must examine whether this is true only in the case of PTSD or is a general organizing principle in the human brain. Hum Brain Mapp 38:4479-4496, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  12. Minimum Leakage/Low Cost Duct Connections

    Energy Technology Data Exchange (ETDEWEB)

    John Proctor

    2003-08-01

    Leaky and disconnected joints in HVAC air distribution systems are extremely widespread. The average efficiency of duct systems in homes in the US is approximately 55% with approximately 60% of the loss due to duct leakage. Beyond the energy and emissions penalties caused by these leaks, leaky systems have detrimental comfort, health, and safety effects. The health and safety effects include the delivery of combustion products into the homes due to leakage induced depressurization. Current duct installation practice does not attempt to address the problem. This project developed a prototype Professionally Engineered Duct System that will virtually eliminate air leakage and that can be applied in new and replacement installations at the same labor cost as current designs. It uses snap-together duct fittings that will not come apart, can be applied to all types of duct systems, and cannot be separated without exceptional force. its use would require minimal changes to current installation practice. The research team developed the prototype through a multi-step process beginning with a functional analysis of duct connections. This was followed by identifying duct sealing and attachment methods offering potential to meet design objectives, evaluating the designs in terms of function and economic feasibility, and building and testing the most promising design option. Two versions of this design were developed through a test, revise, retest process. One application was to a rigid sheet metal duct, the other was to a helix core flex duct. The process produced a sheet metal application with 1/20th the leakage of a standard connection and a flex duct application with 1/10th the leakage of a standard connection. A patent search has found that the design will not infringe on existing patents and is patentable.

  13. Grid-connected wind and photovoltaic system

    Science.gov (United States)

    Devabakthuni, Sindhuja

    The objective of this thesis is to design a grid connected wind and photovoltaic system. A new model of converter control was designed which maintains the voltage of the bus to grid as constant when combined system of solar and wind is connected to AC bus. The model is designed to track maximum power at each point irrespective of changes in irradiance, temperature and wind speed which affects the power supplied to grid. Solar power from the sun is not constant as it is affected by changes in irradiances and temperature. Even the wind power is affected by wind speed. A MPPT controller was designed for both systems. A boost converter is designed which uses the pulses from MPPT controller to boost the output. Wind system consists of wind turbine block from the MATLAB with a pitch angle controller to maintain optimum pitch angle. The output from wind turbine is connected to a permanent magnet synchronous generator. The unregulated DC output from the photovoltaic system is directly given to boost converter. The AC output from the wind system is given to an uncontrolled rectifier to get a unregulated DC output. The unregulated DC output goes to the boost converter. A voltage source inverter was designed which converts the rectified DC output from the boost converter to AC power. The inverter is designed to maintain constant AC bus voltage irrespective of the disturbances in the power supply. Photovoltaic and wind systems are individually designed for 5KW each in MATLAB-Simulink environment. In this thesis, the models were subjected to changes in irradiance, temperature and wind speed and the results were interpreted. The model was successful in tracking maximum at every instant and the AC bus voltage was maintained constant throughout the simulation.

  14. Multiple, connective intellection: the condition for invention

    Directory of Open Access Journals (Sweden)

    C S (Fanie de Beer

    2015-11-01

    Full Text Available Since this article involves invention, the conditions for inventiveness become the issue: assuming multiple reality; thinking in a special way; transgressing boundaries; acknowledging networks (in the terms of Michel Serres: communication, transduction, interference, distribution, passages between the sciences. There are, however, misplaced expectations: technology should work wonders in this regard while forgetting that humans, redefined though, remain the key to establish connections and networks between people, paradigms, disciplines, sciences and technologies. Against this background, Michel Serres’s emphasis on invention and “thinking as invention” and his a-critical anti-method – ‘connective, multiple intellection’ which is a special kind of thought – are desperately needed. Guattari’s articulation of the three ecologies and the ecosophic views he developed in this regard provides a significant amplification of the approach of ‘multiple connective intellection’. These insights can be enlightened and strongly driven home through the views of Latour with an anthropological and socio-dynamic perspective on the scientific endeavour with the articulation of the actor-network theory inherited from Serres. The thoughtful beyond-methodology of Edgar Morin with his strong noological position as the ultimate condition for inventiveness, and Gregory Ulmer with his special emphasis on invention and inventiveness, especially with the help and assistance of electronic means (video and internet, and with his work with the architect Bernard Tschumi on invention and inventiveness, are of special significance in the sphere of inventiveness, the real and final guarantee for a spirited re-enchantment of the world as well as the final demonstration that the battle for intelligence as opposed to ignorance, stupidity and barbarism can be fought with great hope to succeed.

  15. Maturing thalamocortical functional connectivity across development

    Directory of Open Access Journals (Sweden)

    Damien Fair

    2010-05-01

    Full Text Available Recent years have witnessed a surge of investigations examining functional brain organization using resting-state functional connectivity MRI (rs-fcMRI. To date, this method has been used to examine systems organization in typical and atypical developing populations. While the majority of these investigations have focused on cortical-cortical interactions, cortical-subcortical interactions also mature into adulthood. Innovative work by Zhang et al (Zhang et al., 2008 in adults have identified methods that utilize rs-fcMRI and known thalamo-cortical topographic segregation to identify functional boundaries in the thalamus that are remarkably similar to known thalamic nuclear grouping. However, despite thalamic nuclei being well formed early in development, the developmental trajectory of functional thalamo-cortical relations remains unexplored. Thalamic maps generated by rs-fcMRI are based on functional relationships, and should modify with the dynamic thalamo-cortical changes that occur throughout maturation. To examine this possibility, we employed a strategy as previously described by Zhang et al to a sample of healthy children, adolescents, and adults. We found strengthening functional connectivity of the frontal cortex with dorsal/anterior subdivisions of the thalamus across age groups. Temporal lobe connectivity with ventral/midline/posterior subdivisions of the thalamus weakened with age. Changes in sensory and motor thalamo-cortical interactions were limited. These findings are consistent with known anatomical and physiological cortical-subcortical changes over development. The methods and developmental context provided here will be important for relating how cortical-subcortical interactions relate to models of typically developing behavior and developmental neuropsychiatric disorders.

  16. Connected rectilinear graphs on point sets

    Directory of Open Access Journals (Sweden)

    Maarten Löffler

    2011-02-01

    Full Text Available Let V be a set of n points in Rd. We study the question whether there exists an orientation such that V is the vertex set of a connected rectilinear graph in that orientation. A graph is rectilinear if its edges are straight line segments in d pairwise perpendicular directions. We prove that at most one such orientation can be possible, up to trivial rotations of 90 degrees around some axis. In addition, we present an algorithm for computing this orientation (if it exists in O(nd time when d≥2.

  17. Living Autoethnography: Connecting Life and Research

    Directory of Open Access Journals (Sweden)

    Faith Wambura Ngunjiri

    2010-01-01

    Full Text Available Autoethnography is a qualitative research method that utilizes data about self and context to gain an understanding of the connectivity between self and others. This introductory article exposes the reader to our own praxis of collaborative autoethnography which we used to interrogate how we navigate the US academy as immigrant women faculty. Before introducing the articles in this special issue, we explore the autoethnography continuum, provide sample areas covered by autoethnographers, and explicate the practice of collaborative autoethnography. We conclude this piece with implications for future use of autoethnography as research method.

  18. Finite Element analysis of jar connections

    DEFF Research Database (Denmark)

    Kristensen, A.; Toor, Kashif; Solem, Sigurd

    2005-01-01

    A new tool joint system is considered. Traditionally these rotary connections have been designed with only one shoulder geometry. However, in order to increase the torque rating of the tool joint, a new design is introduced using two shoulders. This design allow reduced tool joint dimensions wher...... whereby down-hole equipment more easily can be fitted. In order to evaluate the validity of the design, finite element analysis have been performed in ANSYS. The results obtained indicate that the new design is valid and further tests can be performed....

  19. Totally Connected Healthcare with TV White Spaces.

    Science.gov (United States)

    Katzis, Konstantinos; Jones, Richard W; Despotou, Georgios

    2017-01-01

    Recent technological advances in electronics, wireless communications and low cost medical sensors generated a plethora of Wearable Medical Devices (WMDs), which are capable of generating considerably large amounts of new, unstructured real-time data. This contribution outlines how this data can be propagated to a healthcare system through the internet, using long distance Radio Access Networks (RANs) and proposes a novel communication system architecture employing White Space Devices (WSD) to provide seamless connectivity to its users. Initial findings indicate that the proposed communication system can facilitate broadband services over a large geographical area taking advantage of the freely available TV White Spaces (TVWS).

  20. Insulation coordination for delta connected transformers

    Energy Technology Data Exchange (ETDEWEB)

    Keri, A.J.F.; Musa, Y.I.; Halladay, J.A. (American Electric Power Service Corp., Columbus, OH (United States))

    1994-04-01

    It is common practice to install only phase to ground surge arresters for transformer insulation protection against electrical stresses. However, this may not adequately protect the delta connected transformer phase to phase winding insulation. High phase to phase overvoltages at the transformer terminals, due to capacitor switching, have been reported. This paper describes the excessive phase to phase overvoltages that can also occur due to wave propagation and surge transfer through transformers. This paper points out the need for surge arrester arrangements that protect both, phase to phase and phase to ground transformer insulations. Surge arrester arrangements, selection criteria, installation practices, and application considerations are discussed in this paper.