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Sample records for profiles part ii

  1. Attachment and Learning. Part II: The Learning Profile of the Avoidant and Disorganized Attachment Patterns

    Science.gov (United States)

    Geddes, Heather

    2005-01-01

    Using the framework of Attachment Theory, and following on from Part 1, further patterns of Attachment Behaviour are described and linked to responses in the classroom. The Avoidant and Disorganized patterns are described and linked to responses in the classroom to the teacher and to the educational task illustrated by examples from practice.…

  2. CLIMABR parte II: geração do perfil de precipitação CLIMABR part II: generation of precipitation profile

    Directory of Open Access Journals (Sweden)

    Vicente de P. S. de Oliveira

    2005-09-01

    Full Text Available As pesquisas sobre precipitação no Brasil têm-se restringido à previsão da lâmina total máxima ou da intensidade máxima provável, esta feita com base em séries históricas. Poucos trabalhos, no entanto, consideram o perfil correspondente a essas precipitações. A falta de modelos representativos tem forçado o uso daqueles desenvolvidos no exterior; contudo, os resultados obtidos demonstram, muitas vezes, que eles não representam adequadamente as condições climáticas típicas do Brasil. Objetivou-se, com o presente trabalho, detalhar complementarmente o desenvolvimento do modelo denominado CLIMABR, descrito por Oliveira et al. (2003, e mostrar sua aplicação para a geração do perfil instantâneo associado às séries sintéticas de precipitação, para as condições climáticas encontradas no Estado do Rio de Janeiro. Na série sintética gerada foram obtidos, para cada dia simulado, entre outros resultados, a duração dos eventos e os valores padronizados da intensidade máxima instantânea de precipitação e do tempo de sua ocorrência ao longo dos eventos. Os dois últimos valores obtidos no modelo foram utilizados para a obtenção do perfil de precipitação representado por uma função dupla exponencial, que foi ajustada a cada evento diário.The research about precipitation in Brazil has been restricted, most of time, to predict the maximum - total - or probable maximum intensity, this being done on the basis of historical series. Only few projects consider the corresponding profiles to these precipitations. The lack of representative models has forced the use of models developed abroad, despite the fact that the obtained results demonstrate, many times, was in inadequability to represent the typical climatic conditions in Brazil. The aim of the present work to detail complementarily to the development of the CLIMABR model, described by Oliveira et al. (2003, and show its application for instantaneous profile

  3. Stiffnites. Part II

    Directory of Open Access Journals (Sweden)

    Maria Teresa Pareschi

    2011-06-01

    Full Text Available

    The dynamics of a stiffnite are here inferred. A stiffnite is a sheet-shaped, gravity-driven submarine sediment flow, with a fabric made up of marine ooze. To infer stiffnite dynamics, order of magnitude estimations are used. Field deposits and experiments on materials taken from the literature are also used. Stiffnites can be tens or hundreds of kilometers wide, and a few centimeters/ meters thick. They move on the sea slopes over hundreds of kilometers, reaching submarine velocities as high as 100 m/s. Hard grain friction favors grain fragmentation and formation of triboelectrically electrified particles and triboplasma (i.e., ions + electrons. Marine lipids favor isolation of electrical charges. At first, two basic assumptions are introduced, and checked a posteriori: (a in a flowing stiffnite, magnetic dipole moments develop, with the magnetization proportional to the shear rate. I have named those dipoles as Ambigua. (b Ambigua are ‘vertically frozen’ along stiffnite streamlines. From (a and (b, it follows that: (i Ambigua create a magnetic field (at peak, >1 T. (ii Lorentz forces sort stiffnite particles into two superimposed sheets. The lower sheet, L+, has a sandy granulometry and a net positive electrical charge density. The upper sheet, L–, has a silty muddy granulometry and a net negative electrical charge density; the grains of sheet L– become finer upwards. (iii Faraday forces push ferromagnetic grains towards the base of a stiffnite, so that a peak of magnetic susceptibility characterizes a stiffnite deposit. (iv Stiffnites harden considerably during their motion, due to magnetic confinement. Stiffnite deposits and inferred stiffnite characteristics are compatible with a stable flow behavior against bending, pinch, or other macro instabilities. In the present report, a consistent hypothesis about the nature of Ambigua is provided.

  4. The effects of electrical stimulation on body composition and metabolic profile after spinal cord injury--Part II.

    Science.gov (United States)

    Gorgey, Ashraf S; Dolbow, David R; Dolbow, James D; Khalil, Refka K; Gater, David R

    2015-01-01

    Diet and exercise are cornerstones in the management of obesity and associated metabolic complications, including insulin resistance, type 2 diabetes, and disturbances in the lipid profile. However, the role of exercise in managing body composition adaptations and metabolic disorders after spinal cord injury (SCI) is not well established. The current review summarizes evidence about the efficacy of using neuromuscular electrical stimulation or functional electrical stimulation in exercising the paralytic lower extremities to improve body composition and metabolic profile after SCI. There are a number of trials that investigated the effects on muscle cross-sectional area, fat-free mass, and glucose/lipid metabolism. The duration of the intervention in these trials varied from 6 weeks to 24 months. Training frequency ranged from 2 to 5 days/week. Most studies documented significant increases in muscle size but no noticeable changes in adipose tissue. While increases in skeletal muscle size after twice weekly training were greater than those trials that used 3 or 5 days/week, other factors such as differences in the training mode, i.e. resistance versus cycling exercise and pattern of muscle activation may be responsible for this observation. Loading to evoke muscle hypertrophy is a key component in neuromuscular training after SCI. The overall effects on lean mass were modest and did not exceed 10% and the effects of training on trunk or pelvic muscles remain unestablished. Most studies reported improvement in glucose metabolism with the enhancement of insulin sensitivity being the major factor following training. The effect on lipid profile is unclear and warrants further investigation.

  5. The effects of electrical stimulation on body composition and metabolic profile after spinal cord injury – Part II

    Science.gov (United States)

    Gorgey, Ashraf S.; Dolbow, David R.; Dolbow, James D.; Khalil, Refka K.; Gater, David R.

    2015-01-01

    Diet and exercise are cornerstones in the management of obesity and associated metabolic complications, including insulin resistance, type 2 diabetes, and disturbances in the lipid profile. However, the role of exercise in managing body composition adaptations and metabolic disorders after spinal cord injury (SCI) is not well established. The current review summarizes evidence about the efficacy of using neuromuscular electrical stimulation or functional electrical stimulation in exercising the paralytic lower extremities to improve body composition and metabolic profile after SCI. There are a number of trials that investigated the effects on muscle cross-sectional area, fat-free mass, and glucose/lipid metabolism. The duration of the intervention in these trials varied from 6 weeks to 24 months. Training frequency ranged from 2 to 5 days/week. Most studies documented significant increases in muscle size but no noticeable changes in adipose tissue. While increases in skeletal muscle size after twice weekly training were greater than those trials that used 3 or 5 days/week, other factors such as differences in the training mode, i.e. resistance versus cycling exercise and pattern of muscle activation may be responsible for this observation. Loading to evoke muscle hypertrophy is a key component in neuromuscular training after SCI. The overall effects on lean mass were modest and did not exceed 10% and the effects of training on trunk or pelvic muscles remain unestablished. Most studies reported improvement in glucose metabolism with the enhancement of insulin sensitivity being the major factor following training. The effect on lipid profile is unclear and warrants further investigation. PMID:25001669

  6. Wind Profiles and Wave Spectra for Potential Wind Farms in South China Sea. Part II: Wave Spectrum Model

    Directory of Open Access Journals (Sweden)

    Yichao Liu

    2017-01-01

    Full Text Available Along with the commercialization of offshore wind energy in China, the South China Sea has been identified as ideal for constructing offshore wind farms, especially for farms consisting of floating wind turbines over deep waters. Since the wind profiles and wave spectra are somewhat primitive for the design of an offshore wind turbine, engineering models describing the wind and wave characteristics in the South China Sea area are necessary for the offshore wind energy exploitation given the meteorological, hydrological, and geographical differences between the South China Sea and the North/Norwegian Sea, where the commonly used wind profile and wave spectrum models were designated. In the present study; a series of numerical simulations were conducted to reveal the wave characteristics in the South China Sea under both typhoon and non-typhoon conditions. By analyzing the simulation results; the applicability of the Joint North Sea Wave Project (JONSWAP spectrum model; in terms of characterizing the wind-induced wave fields in the South China Sea; was discussed. In detail; the key parameters of the JONSWAP spectrum model; such as the Phillips constant; spectral width parameter; peak-enhancement factor, and high frequency tail decay; were investigated in the context of finding suitable values.

  7. Designing screened enclosures: Part II.

    Science.gov (United States)

    Bearpark, J

    2006-03-01

    Techniques to achieve cost-effective emissions and immunity screening solutions that meet electromagnetic compatibility requirements were provided in Part I of this article, which covered design options for seams and gaskets. Part II continues with a discussion of materials compatibility, corrosion and apertures.

  8. Assistência domiciliaria ao idoso: perfil do cuidador formal - parte II Asistencia domiciliar al anciano: perfil del cuidador formal - parte II The home care of elderly: caregiver profile - part two

    Directory of Open Access Journals (Sweden)

    Kozue Kawasaki

    2001-12-01

    Full Text Available O idoso fragilizado, mantido em seu domicílio, requer cuidados específicos, os quais são realizados muitas vezes por pessoas contratadas pela família para tal, denominadas cuidadores formais. Frente o aumento da oferta de trabalho destas pessoas e a escassez de literatura nacional sobre seu perfiL, desenvolvemos um estudo com 41 pessoas que ofereceram seus serviços através de anúncios em dois jornais de maior circulação no município de Campinas, São Paulo. Tal estudo teve por objetivos: 1. caracterizar estes cuidadores (este objetivo foi contemplado com um artigo publicado anteriormente e 2. verificar as atividades propostas para a assistência ao idoso. No presente trabalho serão apresentados os dados referentes ao segundo objetivo.El anciano debilitado, mantenido en su habitación, carece de cuidados específicos, los cuales han sido realizados muchas veces por personas contratadas, denominadas cuidadores formales. Frente al aumento de oferta de trabajo de estas personas y a la escasez de literatura sobre el perfil, desarrollamos un estudio con 41 anunciantes que ofrecieron sus servicios dos periódicos de grande circulación en el municipio de Campinas, San Pablo, con los siguientes objetivos: 1. caracterizar estos cuidadores y 2. verificar las actividades propuestas para la asistencial al anciano. El presente trabajo presenta los datos referentes a lo secundo objetivo.The frail elderly, maintained in its home, request specific cares, which are accomplished many times by people contracted, denominated formal caregivers. With the increase of the offer of these people's work and the shortage literature on its profile, we developed a study with 41 advertisers that offered their services in two newspapers of larger circulation in the city of Campinas, São Paulo, with the following objectives: 1. to characterize these caregivers and 2. to verify the activities proposals for care to the elderly. In the present work the referring data

  9. Use of DNA profiles for investigation using a simulated national DNA database: Part II. Statistical and ethical considerations on familial searching.

    Science.gov (United States)

    Hicks, T; Taroni, F; Curran, J; Buckleton, J; Castella, V; Ribaux, O

    2010-10-01

    Familial searching consists of searching for a full profile left at a crime scene in a National DNA Database (NDNAD). In this paper we are interested in the circumstance where no full match is returned, but a partial match is found between a database member's profile and the crime stain. Because close relatives share more of their DNA than unrelated persons, this partial match may indicate that the crime stain was left by a close relative of the person with whom the partial match was found. This approach has successfully solved important crimes in the UK and the USA. In a previous paper, a model, which takes into account substructure and siblings, was used to simulate a NDNAD. In this paper, we have used this model to test the usefulness of familial searching and offer guidelines for pre-assessment of the cases based on the likelihood ratio. Siblings of "persons" present in the simulated Swiss NDNAD were created. These profiles (N=10,000) were used as traces and were then compared to the whole database (N=100,000). The statistical results obtained show that the technique has great potential confirming the findings of previous studies. However, effectiveness of the technique is only one part of the story. Familial searching has juridical and ethical aspects that should not be ignored. In Switzerland for example, there are no specific guidelines to the legality or otherwise of familial searching. This article both presents statistical results, and addresses criminological and civil liberties aspects to take into account risks and benefits of familial searching. Copyright © 2009 Elsevier Ireland Ltd. All rights reserved.

  10. Exploring Water Pollution. Part II

    Science.gov (United States)

    Rillo, Thomas J.

    1975-01-01

    This is part two of a three part article related to the science activity of exploring environmental problems. Part one dealt with background information for the classroom teacher. Presented here is a suggested lesson plan on water pollution. Objectives, important concepts and instructional procedures are suggested. (EB)

  11. X-pinch. Part II

    Energy Technology Data Exchange (ETDEWEB)

    Pikuz, S. A., E-mail: pikuz@mail.ru; Shelkovenko, T. A. [Russian Academy of Sciences, Lebedev Physical Institute (Russian Federation); Hammer, D. A. [Cornell University (United States)

    2015-06-15

    Results of experimental studies of the X-pinch since its invention and implementation in 1982 at the Lebedev Physical Institute are presented. The review consists of two parts. The first part briefly outlines the history of creation and studies of X-pinches, describes the diagnostic techniques and devices developed during these studies, and presents the main results obtained in studying the physical processes occurring in the X-pinch. The second part is devoted to the results of detailed studies of the spatial, temporal, and spectral characteristics of the X-pinch hot spot—the region where the highest plasma parameters are achieved and which is a source of X-ray emission with extreme parameters. Some results of X-pinch simulations are also presented.

  12. Revenue cycle management, Part II.

    Science.gov (United States)

    Crew, Matt

    2007-01-01

    The proper management of your revenue cycle requires the application of "best practices" and the continual monitoring and measuring of the entire cycle. The correct technology will enable you to gain the insight and efficiencies needed in the ever-changing healthcare economy. The revenue cycle is a process that begins when you negotiate payor contracts, set fees, and schedule appointments and continues until claims are paid in full. Every single step in the cycle carries equal importance. Monitoring all phases and a commitment to continually communicating the results will allow you to achieve unparalleled success. In part I of this article, we explored the importance of contracting, scheduling, and case management as well as coding and clinical documentation. We will now take a closer look at the benefits charge capture, claim submission, payment posting, accounts receivable follow-up, and reporting can mean to your practice.

  13. Unlearning Established Organizational Routines--Part II

    Science.gov (United States)

    Fiol, C. Marlena; O'Connor, Edward J.

    2017-01-01

    Purpose: The purpose of Part II of this two-part paper is to uncover important differences in the nature of the three unlearning subprocesses, which call for different leadership interventions to motivate people to move through them. Design/methodology/approach: The paper draws on research in behavioral medicine and psychology to demonstrate that…

  14. Temperature profiles from XBT casts from the CARIBOU REEFER II as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1981-08-22 to 1981-08-23 (NODC Accession 8100650)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the CARIBOU REEFER II from 22 August 1981 to 23 August 1981. Data were collected by the National Marine...

  15. Temperature profiles from XBT casts from the CARIBOU REEFER II and other platforms as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1979-08-28 to 1979-11-22 (NODC Accession 7900342)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the CARIBOU REEFER II and other platforms from 28 August 1979 to 22 November 1979. Data were collected by the...

  16. Temperature profiles from XBT casts from the CARIBOU REEFER II as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1980-11-11 (NODC Accession 8000591)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the CARIBOU REEFER II from 11 November 1980. Data were collected by the National Marine Fisheries Service...

  17. Temperature profiles from XBT casts from the CARIBOU REEFER II as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1981-06-10 to 1981-06-11 (NODC Accession 8100563)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the CARIBOU REEFER II from 10 June 1981 to 11 June 1981. Data were collected by the National Marine Fisheries...

  18. Temperature profiles from XBT casts from the CARIBOU REEFER II as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1981-04-08 to 1981-04-09 (NODC Accession 8100553)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the CARIBOU REEFER II from 08 April 1981 to 09 April 1981. Data were collected by the National Marine...

  19. Temperature profiles from XBT casts from the CARIBOU REEFER II as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1981-03-09 to 1981-03-10 (NODC Accession 8100487)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the CARIBOU REEFER II from 09 March 1981 to 10 March 1981. Data were collected by the National Marine...

  20. Temperature profiles from XBT casts from the CARIBOU REEFER II as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1981-02-24 to 1981-02-25 (NODC Accession 8100489)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the CARIBOU REEFER II from 24 February 1981 to 25 February 1981. Data were collected by the National Marine...

  1. Temperature profiles from XBT casts from the CARIBOU REEFER II as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1979-08-03 (NODC Accession 7900261)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the CARIBOU REEFER II from 03 August 1979. Data were collected by the National Marine Fisheries Service...

  2. Temperature profiles from XBT casts from the CARIBOU REEFER II and other platforms as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1980-06-05 to 1980-06-26 (NODC Accession 8000459)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the CARIBOU REEFER II and other platforms from 05 June 1980 to 26 June 1980. Data were collected by the...

  3. Temperature profiles from XBT casts from the CARIBOU REEFER II as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1980-10-20 to 1980-10-21 (NODC Accession 8100556)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the CARIBOU REEFER II from 20 October 1980 to 21 October 1980. Data were collected by the National Marine...

  4. Temperature profiles from XBT casts from the CARIBOU REEFER II as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1980-12-14 to 1980-12-15 (NODC Accession 8000623)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the CARIBOU REEFER II from 14 December 1980 to 15 December 1980. Data were collected by the National Marine...

  5. Temperature profiles from XBT casts from the CARIBOU REEFER II as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1981-07-22 to 1981-07-23 (NODC Accession 8100604)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the CARIBOU REEFER II from 22 July 1981 to 23 July 1981. Data were collected by the National Marine Fisheries...

  6. Temperature profiles from XBT casts from the CARIBOU REEFER II as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1981-05-30 to 1981-05-31 (NODC Accession 8100564)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the CARIBOU REEFER II from 30 May 1981 to 31 May 1981. Data were collected by the National Marine Fisheries...

  7. Temperature profiles from XBT casts from the CARIBOU REEFER II as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1981-09-06 to 1981-09-07 (NODC Accession 8100654)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the CARIBOU REEFER II from 06 September 1981 to 07 September 1981. Data were collected by the National Marine...

  8. Temperature profiles from XBT casts from the CARIBOU REEFER II and other platforms as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1979-05-19 to 1980-01-02 (NODC Accession 8000020)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the CARIBOU REEFER II and other platforms from 19 May 1979 to 02 January 1980. Data were collected by the...

  9. Temperature profiles from XBT casts from the CARIBOU REEFER II as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1980-11-13 to 1980-11-14 (NODC Accession 8000611)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the CARIBOU REEFER II from 13 November 1980 to 14 November 1980. Data were collected by the National Marine...

  10. Temperature profiles from XBT casts from the CARIBOU REEFER II as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1980-07-21 to 1980-09-03 (NODC Accession 8000469)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the CARIBOU REEFER II from 21 July 1980 to 03 September 1980. Data were collected by the National Marine...

  11. Temperature profiles from XBT casts from the CARIBOU REEFER II and other platforms as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1980-04-17 to 1980-05-06 (NODC Accession 8000328)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the CARIBOU REEFER II and other platforms from 17 April 1980 to 06 May 1980. Data were collected by the...

  12. Temperature profiles from XBT casts from the CARIBOU REEFER II and other platforms as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1981-08-05 to 1982-03-18 (NODC Accession 8200052)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the CARIBOU REEFER II and other platforms from 05 August 1981 to 18 March 1982. Data were collected by the...

  13. The Conception of Photons–Part II

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 21; Issue 1. The Conception of Photons – Part II: Bose's Derivation, and the Complete Quantum Description of Light. Urjit A Yajnik. General Article Volume 21 Issue 1 January 2016 pp 49-69 ...

  14. Chemical weathering of a marine terrace chronosequence, Santa Cruz, California. Part II: Solute profiles, gradients and the comparisons of contemporary and long-term weathering rates

    Science.gov (United States)

    White, A.F.; Schulz, M.S.; Stonestrom, David A.; Vivit, D.V.; Fitzpatrick, J.; Bullen, T.D.; Maher, K.; Blum, A.E.

    2009-01-01

    changes and/or climate. Pore waters approach thermodynamic saturation with respect to albite at depth in the younger terraces, indicating that weathering rates ultimately become transport-limited and dependent on hydrologic flux. Contemporary rates Rsolute are estimated from linear Na and Si pore weathering gradients bsolute such that Rsolute = frac(qh, bsolute ?? Sv) where Sv is the volumetric surface area and ?? is the stoichiometric coefficient. Plagioclase weathering rates (0.38-2.8 ?? 10-15 mol m-2 s-1) are comparable to those based on 87Sr/86Sr mass balances and solid-state Na and Ca gradients using analogous gradient approximations. In addition, contemporary solute gradients, under transport-limited conditions, approximate long-term solid-state gradients when normalized against the mass of protolith plagioclase and its corresponding aqueous solubility. The multi-faceted weathering analysis presented in this paper is perhaps the most comprehensive yet applied to a single field study. Within uncertainties of the methods used, present day weathering rates, based on solute characterizations, are comparable to average long-term past rates as evidenced by soil profiles.

  15. Thyroid disorders. Part II: hypothyroidism and thyroiditis.

    Science.gov (United States)

    Little, James W

    2006-08-01

    Part II of the series on thyroid disorders discusses hypothyroidism and thyroiditis that may be found in dental patients. An overview of the conditions is presented. Presenting signs and symptoms, laboratory tests used to diagnose hypothyroidism and thyroiditis, and their medical management is discussed. The dental management of patients with hypothyroidism is discussed in detail. The dentist by detecting the early signs and symptoms of hypothyroidism and thyroiditis can refer the patient for medical diagnosis and treatment and avoid potential complications of treating patients with uncontrolled disease. Patients with thyroiditis may have a short period of being hyperthyroid and it may be best to avoid routine dental treatment during that period. Patients with suppurative thyroiditis should not receive routine dental treatment during the acute stage of the disease. The end stage of Hashimoto's thyroiditis results in hypothyroidism. Central nervous system depressants, sedatives, or narcotic analgesics must be avoided in patients with severe hypothyroidism because significant respiratory depression may occur. In addition, myxedematous coma, particularly in elderly hypothyroid patients, can be precipitated by central nervous system depressants, infection, and possibly stressful dental procedures. In medically well-controlled patients the dental treatment plan is not affected and most dental procedures can be offered to these patients.

  16. 46 CFR Appendix II to Part 153 - Metric Units Used in Part 153

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Metric Units Used in Part 153 II Appendix II to Part 153 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Pt. 153, App. II Appendix II to...

  17. 40 CFR Appendix II to Part 86 - Temperature Schedules

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 19 2010-07-01 2010-07-01 false Temperature Schedules II Appendix II... Appendix II to Part 86—Temperature Schedules (a) Ambient temperature cycle for the diurnal emission portion of the evaporative emission test (see § 86.133). Table I—Temperature Versus Time Sequence Use linear...

  18. Stark broadening parameter tables for in II: Part II

    Directory of Open Access Journals (Sweden)

    Dimitrijević M.S.

    2001-01-01

    Full Text Available Electron-, proton-, and ionized helium-impact broadening parameter tables for 101 In II multiplets, are presented as a function of temperature for the perturber density of 1016cm-3. Calculations have been performed within the semiclassical perturbation approach.

  19. Reproduce and die! Why aging? Part II

    NARCIS (Netherlands)

    Schuiling, GA

    Whilst in part I of this diptych on aging the question why aging exists at all is discussed; this part deals with the question which mechanisms underly aging and, ultimately, dying. It appears that aging is not just an active process as such - although all kinds of internal (e.g., oxigen-free

  20. The Conception of Photons – Part II

    Indian Academy of Sciences (India)

    IAS Admin

    theory of relativity and cosmology. Part 1: Planck .... Newton with his formu- lation in 1915 of the general theory of relativity. But .... ship of Bose. It appears that he himself did not grasp the novel assumption he had inadvertently made in his derivation. While the discrete partitioning of the phase space is an important step, the ...

  1. Searching LEXIS and WESTLAW: Part II.

    Science.gov (United States)

    Franklin, Carl

    1986-01-01

    This second of a three-part series compares search features (i.e., truncation symbols, boolean operators, proximity operators, phrase searching, save searches) of two databases providing legal information. Search tips concerning charges and effective searching and tables listing functions of commands and proximity operators for both databases are…

  2. Plasma Astrophysics, Part II Reconnection and Flares

    CERN Document Server

    Somov, Boris V

    2013-01-01

    This two-part book is devoted to classic fundamentals and current practices and perspectives of modern plasma astrophysics. This second part discusses the physics of magnetic reconnection and flares of electromagnetic origin in space plasmas in the solar system, single and double stars, relativistic objects, accretion disks and their coronae. More than 25% of the text is updated from the first edition, including the additions of new figures, equations and entire sections on topics such as topological triggers for solar flares and the magnetospheric physics problem. This book is aimed at professional researchers in astrophysics, but it will also be useful to graduate students in space sciences, geophysics, applied physics and mathematics, especially those seeking a unified view of plasma physics and fluid mechanics.

  3. Plasma Astrophysics, part II Reconnection and Flares

    CERN Document Server

    Somov, Boris V

    2007-01-01

    This well-illustrated monograph is devoted to classic fundamentals, current practice, and perspectives of modern plasma astrophysics. The first part is unique in covering all the basic principles and practical tools required for understanding and working in plasma astrophysics. The second part presents the physics of magnetic reconnection and flares of electromagnetic origin in space plasmas within the solar system; single and double stars, relativistic objects, accretion disks, and their coronae are also covered. This book is designed mainly for professional researchers in astrophysics. However, it will also be interesting and useful to graduate students in space sciences, geophysics, as well as advanced students in applied physics and mathematics seeking a unified view of plasma physics and fluid mechanics.

  4. Shalom Sefarad: Una "erensya" envenenada (Parte II

    Directory of Open Access Journals (Sweden)

    MARINA VARGAS GÓMEZ-URRUTIA

    2015-07-01

    Full Text Available This paper focus the regulation established in the Law 12/2015, June 24 for granting the Spanish nationality to the Sephardic originating from Spain. The second part analyzes the amendments made to the bill during the parliamentary process and critically examines the most important aspects of the final text of the law. En este trabajo se da cuenta de la regulación establecida en la Ley 12/2015, de 24 de junio para la concesión de la nacionalidad española a los sefardíes originarios de España. Esta segunda parte analiza las enmiendas introducidas al Proyecto de Ley durante el proceso parlamentario y examina críticamente los aspectos más relevantes del texto final de la ley.

  5. Vapor phase transformer drying – Part II

    OpenAIRE

    Steeves, Gregory R.

    2016-01-01

    Vapor phase drying is the most effective method for drying transformer insulation in a manufacturing setting. The process does not lend itself well to transformer drying in the field for a variety of reasons, including the difficulty of removing residual kerosene which can cause a potential change in transformer oil flash point. Several techniques are available for transformer insulation drying in both the field and in manufacturing. Vapor phase drying as part of transformer manufacturing is ...

  6. Treatment of superficial mycoses: review - part II

    OpenAIRE

    Dias, Maria Fernanda Reis Gavazzoni; Bernardes-Filho,Fred; Quaresma-Santos,Maria Victória Pinto; Amorim, Adriana Gutstein da Fonseca; Schechtman, Regina Casz; Azulay, David Rubem

    2013-01-01

    Superficial fungal infections of the hair, skin and nails are a major cause of morbidity in the world. Choosing the right treatment is not always simple because of the possibility of drug interactions and side effects. The first part of the article discusses the main treatments for superficial mycoses - keratophytoses, dermatophytosis, candidiasis, with a practical approach to the most commonly-used topical and systemic drugs , referring also to their dosage and duration of use. Promising new...

  7. Implantable microsystems for monitoring and neural rehabilitation, Part II.

    Science.gov (United States)

    Stieglitz, Thomas

    2002-01-01

    Miniaturised implantable biomedical microsystems are opening up completely new markets for diagnosis and therapy products. Part II of this article discusses recent work on distributed intelligent implants and biohybrid systems, which combine microsystems with cells and tissues.

  8. Profile structures of TJ-II stellarator plasmas

    NARCIS (Netherlands)

    Herranz, J.; Pastor, I.; Castejon, F.; de la Luna, E.; Garcia-Cortes, I.; Barth, C. J.; Ascasibar, E.; Sanchez, J.; Tribaldos, V.

    2000-01-01

    Fine structures are found in the TJ-II stellarator electron temperature and density profiles, when they are measured using a high spatial resolution Thomson scattering system. These structures consist of peaks and valleys superimposed to a smooth average. Some irregularities remain in an ensemble

  9. Treatment of superficial mycoses: review - part II*

    Science.gov (United States)

    Dias, Maria Fernanda Reis Gavazzoni; Bernardes-Filho, Fred; Quaresma-Santos, Maria Victória Pinto; Amorim, Adriana Gutstein da Fonseca; Schechtman, Regina Casz; Azulay, David Rubem

    2013-01-01

    Superficial fungal infections of the hair, skin and nails are a major cause of morbidity in the world. Choosing the right treatment is not always simple because of the possibility of drug interactions and side effects. The first part of the article discusses the main treatments for superficial mycoses - keratophytoses, dermatophytosis, candidiasis, with a practical approach to the most commonly-used topical and systemic drugs , referring also to their dosage and duration of use. Promising new, antifungal therapeutic alternatives are also highlighted, as well as available options on the Brazilian and world markets. PMID:24474103

  10. Ayurvedic literature in Urdu (Part-II).

    Science.gov (United States)

    Husain, S A; Kumar Bhatnagar, V; Ali, M

    1999-07-01

    This article is a second part of previous work published with the same title in this Bulletin Vol. 28, 1998, P. nos. 151-158. It contains brief notes on six rare Ayurvedic books in Urdu. It provides two types of information, i.e. (i) Introduction to the books studied and (2) Literary history of Ayurveda of that period in which Urdu language had a prominent role in propagation of Arts and Science. It gives an idea for seeking information on these lines regarding the Ayurvedic works in Arabic and Persian also.

  11. Treatment of superficial mycoses: review. Part II.

    Science.gov (United States)

    Dias, Maria Fernanda Reis Gavazzoni; Bernardes-Filho, Fred; Quaresma-Santos, Maria Victória Pinto; Amorim, Adriana Gutstein da Fonseca; Schechtman, Regina Casz; Azulay, David Rubem

    2013-01-01

    Superficial fungal infections of the hair, skin and nails are a major cause of morbidity in the world. Choosing the right treatment is not always simple because of the possibility of drug interactions and side effects. The first part of the article discusses the main treatments for superficial mycoses - keratophytoses, dermatophytosis, candidiasis, with a practical approach to the most commonly-used topical and systemic drugs , referring also to their dosage and duration of use. Promising new, antifungal therapeutic alternatives are also highlighted, as well as available options on the Brazilian and world markets.

  12. New particle searches in ALEPH (part II)

    CERN Document Server

    Roussarie, A

    1991-01-01

    This report is the second part of the ALEPH search report . I t covers the search for super - symmetric particles (Higgs , chargino s an d neutralinos ) withi n th e framewor k o f th e Minima l Supersymmmetri c Standar d Mode l an d th e searc h fo r composi t charge d lepton s an d neutrinos . Lowe r limit s o f masse s o f suc h ne w particle s ar e given . Mos t o f the m ar e ver y clos e t o th e LE P I kenematica l limit .

  13. Curriculum Redesign in Veterinary Medicine: Part II.

    Science.gov (United States)

    Macik, Maria L; Chaney, Kristin P; Turner, Jacqueline S; Rogers, Kenita S; Scallan, Elizabeth M; Korich, Jodi A; Fowler, Debra; Keefe, Lisa M

    Curricular review is considered a necessary component for growth and enhancement of academic programs and requires time, energy, creativity, and persistence from both faculty and administration. On a larger scale, a comprehensive redesign effort involves forming a dedicated faculty redesign team, developing program learning outcomes, mapping the existing curriculum, and reviewing the curriculum in light of collected stakeholder data. The faculty of the Texas A&M University College of Veterinary Medicine & Biomedical Sciences (TAMU) recently embarked on a comprehensive curriculum redesign effort through partnership with the university's Center for Teaching Excellence. Using a previously developed evidence-based model of program redesign, TAMU created a process for use in veterinary medical education, which is described in detail in the first part of this article series. An additional component of the redesign process that is understated, yet vital for success, is faculty buy-in and support. Without faculty engagement, implementation of data-driven curricular changes stemming from program evaluation may be challenging. This second part of the article series describes the methodology for encouraging faculty engagement through the final steps of the redesign initiative and the lessons learned by TAMU through the redesign process.

  14. DNA from keratinous tissue. Part II

    DEFF Research Database (Denmark)

    Olsen, Maia E.; Bengtsson, Camilla Friis; Bertelsen, Mads Frost

    2012-01-01

    Although good quality DNA can be recovered from the base of the calamus of freshly sampled feathers, as from other fully keratinized tissues such as nail or hair shaft, the quality and quantity of DNA in the majority of feather structures is much poorer. Little research has been performed...... to characterize the quality of this DNA is, and thus what a researcher might be able to achieve when using feathers as a source of DNA. In this review, we expand on our companion article detailing the quality of DNA in nail and hair, by synthesizing published, and new preliminary genetic data obtained from...... feathers. As with nail and hair, we demonstrate that although DNA can, in general, be recovered from all parts of the feather, the quality of such DNA varies. As such, although one can expect a priori that genetic analyses are possible on the feather, for PCR based analyses, it is extremely difficult...

  15. [Seafood poisonings. Part II. Fish poisonings].

    Science.gov (United States)

    Ciszowski, Krzysztof; Mietka-Ciszowska, Aneta

    2012-01-01

    Fish plays a significant role in human life, mainly as part of a balanced healthy diet and a good source of many of nutrients. However, contact with fish may be harmful or even life-threatening to man. Toxic effects, that fish exerts toward men (ichthyotoxism), result from envenomations by poison. ous fish equipped in venom apparatus (ichthyoacanthotoxism), direct contact with venom produced by skin glandules (ichthyocrinotoxism), or consuming fish containing toxins for nutritional purposes (ichthyosarcotoxism). In the present review, different fish-borne food poisonings are presented including their etiology, pathogenesis, symptomatology and treatment. In fact, the majority of fish poisonings are intoxications with toxins primary produced by bacteria, cyanobacteria and algae. These are consumed and accumulated in the food chain by herbivorous and predatory fish, that in turn may be a cause of poisonings in humans.

  16. The sociogeometry of inequality: Part II

    Science.gov (United States)

    Eliazar, Iddo

    2015-05-01

    The study of socioeconomic inequality is of prime economic and social importance, and the key quantitative gauges of socioeconomic inequality are Lorenz curves and inequality indices - the most notable of the latter being the popular Gini index. In this series of papers we present a sociogeometric framework to the study of socioeconomic inequality. In this part we focus on the gap between the rich and the poor, which is quantified by gauges termed disparity curves. We shift from disparity curves to disparity sets, define inequality indices in terms of disparity sets, and introduce and explore a collection of distance-based and width-based inequality indices stemming from the geometry of disparity sets. We conclude with mean-absolute-deviation (MAD) representations of the inequality indices established in this series of papers, and with a comparison of these indices to the popular Gini index.

  17. TEXTILE STRUCTURES FOR AERONAUTICS (PART II

    Directory of Open Access Journals (Sweden)

    SOLER Miquel

    2014-05-01

    Full Text Available Three-dimensional (3D textile structures with better delamination resistance and damage impact tolerance to be applied in composites for structural components is one of the main goals of the aeronautical industry. Textile Research Centre in Canet de Mar has been working since 2008 in this field. Our staff has been designing, developing and producing different textile structures using different production methods and machinery to improve three-dimensional textile structures as fiber reinforcement for composites. This paper describes different tests done in our textile labs from unidirectional structures to woven, knitted or braided 3 D textile structures. Advantages and disadvantages of each textile structure are summarized. The second part of this paper deals with our know-how in the manufacturing and assessing of three-dimensional textile structures during this last five years in the field of textile structures for composites but also in the development of structures for other applications. In the field of composites for aeronautic sector we have developed textile structures using the main methods of textile production, that is to say, weaving, warp knitting, weft knitting and braiding. Comparing the advantages and disadvantages it could be said that braided fabrics, with a structure in the three space axes are the most suitable for fittings and frames.

  18. Generic drugs in dermatology: part II.

    Science.gov (United States)

    Payette, Michael; Grant-Kels, Jane M

    2012-03-01

    In part I, we discussed new drug development, reviewed the history of the generic drug industry, described how generic drugs are approved by the US Food and Drug Administration, and defined the concepts of bioequivalence and therapeutic equivalence. Herein, we explore various factors impacting generic drug use across the different parties involved: the prescriber, the pharmacist, the patient, and the payer. We also include original cost analysis of dermatologic brand name and generic drugs and show the potential cost savings that can be achieved through generic substitution. We conclude with a review of the data addressing potential differences in the effectiveness of brand name versus generic drugs in dermatology. The cost of brand name and generic medications is highly variable by pharmacy, state, and payer. We used one source (www.drugstore.com) as an example and for consistency across all medications discussed herein. Prices included here may not reflect actual retail prices across the United States. Copyright © 2011 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.

  19. Society. Part II: moderate to severe psoriasis

    Directory of Open Access Journals (Sweden)

    Jacek Szepietowski

    2014-11-01

    Full Text Available Psoriasis is a chronic inflammatory skin disease affecting about 1–3% of the general population. Recent years have seen great development in the treatment of this dermatosis, especially regarding moderate to severe psoriasis. More numerous and more widely available systemic therapies raise new challenges for all physicians treating patients with psoriasis. New questions arise about patients’ follow-up and long-term safety of such therapies. To meet the expectations of Polish dermatologists, we have prepared a second part of guidelines on the treatment of psoriasis, particularly concentrated on the therapy of severe forms of this disease. We hope that our suggestions will be valuable for physicians in their daily clinical practice. However, we would like to underline that every guideline is characterized by some vagueness, and the final decision about diagnosis and therapy should always be made individually for every patient based on the patient’s current clinical status and the most up-to-date scientific literature data.

  20. [Conceptual Development in Cognitive Science. Part II].

    Science.gov (United States)

    Fierro, Marco

    2012-03-01

    Cognitive science has become the most influential paradigm on mental health in the late 20(th) and the early 21(st) centuries. In few years, the concepts, problem approaches and solutions proper to this science have significantly changed. Introduction and discussion of the fundamental concepts of cognitive science divided in four stages: Start, Classic Cognitivism, Connectionism, and Embodying / Enacting. The 2(nd) Part of the paper discusses the above mentioned fourth stage and explores the clinical setting, especially in terms of cognitive psychotherapy. The embodying/enacting stage highlights the role of the body including a set of determined evolutionary movements which provide a way of thinking and exploring the world. The performance of cognitive tasks is considered as a process that uses environmental resources that enhances mental skills and deploys them beyond the domestic sphere of the brain. On the other hand, body and mind are embedded in the world, thus giving rise to cognition when interacting, a process known as enacting. There is a close connection between perception and action, hence the interest in real-time interactions with the world rather than abstract reasoning. Regarding clinics, specifically the cognitive therapy, there is little conceptual discussion maybe due to good results from practice that may led us to consider that theoretical foundations are firm and not problem-raising. Copyright © 2012 Asociación Colombiana de Psiquiatría. Publicado por Elsevier España. All rights reserved.

  1. Development of aero-engines, part II

    Energy Technology Data Exchange (ETDEWEB)

    Dehn, K.

    1943-01-01

    In the second part of his paper, Mr. Dehn enters into the area of problems in engine construction and design. The main question was, how can more power be coaxed from an engine without increasing its stroke displacement and weight. To begin with, a change in combustion-chamber configuration was made. A hemispheric chamber appeared to be the best design. Into this new design was incorporated a system to swirl the fuel-air mixture for better combustion and more power. Also needed was relocation of the spark plug. Since there was better combustion, valves had to be improved. These were hollowed, filled with sodium and finished with chromium or stellite for more hardness. However, the temperature created by these improvements proved to be a serious problem in engine durability. Heat corrosion destroyed pistons and rings, causing the engine not just to seize-up, but to come apart. This resulted in the loss of aircraft. Finally, a system of cooling the pistons from beneath by an oil spray increased both performance and piston life. Dehn summarizes his paper by comparing two cylinder units from Curtis-Wright radial engines, one old, the other new. He claims that these represented advances in engine technology in all areas he discussed. First, the size had not been increased, but the newer one developed more power. This had been accomplished, he reports, by fuel development reducing pre-detonation. The super-charging, and most important, the re-design of the cooling fins on the cylinder head exterior, provided greater thermal capacity for the engine. In this way, power had been increased more than 100 percent. The author concludes his paper by stating that this type of development is possible only through advances in, and use of, materials technology. That would involve intensive co-operation between the scientists and engineers working in fuels development and aviation engineering.

  2. Kick, Glide, Pole! Cross-Country Skiing Fun (Part II)

    Science.gov (United States)

    Duoos, Bridget A.

    2012-01-01

    Part I of Kick, Glide, Pole! Cross-Country Skiing Fun, which was published in last issue, discussed how to select cross-country ski equipment, dress for the activity and the biomechanics of the diagonal stride. Part II focuses on teaching the diagonal stride technique and begins with a progression of indoor activities. Incorporating this fun,…

  3. Photoprotection: part II. Sunscreen: development, efficacy, and controversies.

    Science.gov (United States)

    Jansen, Rebecca; Osterwalder, Uli; Wang, Steven Q; Burnett, Mark; Lim, Henry W

    2013-12-01

    In addition to the naturally occurring, physical, and systemic photoprotective agents reviewed in part I, topical ultraviolet radiation filters are an important cornerstone of photoprotection. Sunscreen development, efficacy, testing, and controversies are reviewed in part II of this continuing medical education article. Copyright © 2013 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.

  4. Minimizing Glovebox Glove Breaches: PART II.

    Energy Technology Data Exchange (ETDEWEB)

    Cournoyer, M. E. (Cournoyer, Michael E.); Andrade, R.M. (Rose M.); Taylor, D. J. (David J.); Stimmel, J. J. (Jay J.); Zaelke, R. L. (Robyn L.); Balkey, J. J. (James J.)

    2005-01-01

    As a matter of good business practices, a team of glovebox experts from Los Alamos National Laboratory (LANL) has been assembled to proactively investigate processes and procedures that minimize unplanned breaches in the glovebox, e.g., glove failures. A major part of this effort involves the review of glovebox glove failures that have occurred at the Plutonium Facility and at the Chemical and Metallurgy Research Facility. Information dating back to 1993 has been compiled from formal records. This data has been combined with information obtained from a baseline inventory of about 9,000 glovebox gloves. The key attributes tracked include those related to location, the glovebox glove, type and location of breaches, the worker, and the consequences resulting from breaches. This glovebox glove failure analysis yielded results in the areas of the ease of collecting this type of data, the causes of most glove failures that have occurred, the effectiveness of current controls, and recommendations to improve hazard control systems. As expected, a significant number of breaches involve high-risk operations such as grinding, hammering, using sharps (especially screwdrivers), and assembling equipment. Surprisingly, tasks such as the movement of equipment and material between gloveboxes and the opening of cans are also major contributions of breaches. Almost half the gloves fail within a year of their install date. The greatest consequence for over 90% of glovebox glove failures is alpha contamination of protective clothing. Personnel self-monitoring at the gloveboxes continues to be the most effective way of detecting glovebox glove failures. Glove failures from these tasks can be reduced through changes in procedures and the design of remote-handling apparatus. The Nuclear Materials Technology Division management uses this information to improve hazard control systems to reduce the number of unplanned breaches in the glovebox further. As a result, excursions of contaminants

  5. Apudomas Pancreáticos (Parte II

    Directory of Open Access Journals (Sweden)

    Alfredo L. Jácome

    1990-12-01

    Full Text Available

    Aspectos Clínicos

    I. Diagnóstico de los Apudomas
    En este apartado describiremos algunos de los aspectos más relevantes en cuanto al diagnóstico clínico, paraclínico y anatomopatológico de los apudomas conocidos en el páncreas, basándonos en algunas casuísticas nacionales y extranjeras.

    A. Insulinoma
    En 1927 se informó el primer caso en la Clínica Mayo. Esta misma institución posee una de las series más grandes sobre el tema con 200 casos reportados; sin embargo, su incidencia global es del orden de menos de I caso por 100.000 habitantes. En una serie de 1.067 pacientes realizada en Italia, el tumor se presentó aproximadamente en un 60% en mujeres y un 40% en hombres, siendo el rango de edad entre los 30 y 60 años (21.

    l. Manifestaciones clínicas
    Las manifestaciones son debidas a la hipoglicemia secundaria al hiperinsulinismo circulante.

    Los síntomas neurosiquiátricos incluyen: pérdida de conciencia, confusión, vértigo, alteraciones visuales, astenia, coma profundo y epilepsia; se han reportado casos con daño del sistema nervioso central irreversible y parálisis temporal; además también puede haber somnolencia, amnesia, ataxia, cefalea, parestesias, signo de Babinski, agitación e irritabilidad.

    Estos se explican, en gran parte, debido a que elcerebro depende casi exclusivamente de la oxidación de la glucosa para proveer sus necesidades energéticas. En estos pacientes también son frecuentes síntomas de tipo adrenérgico tales como sudoración, temblor, empalidecimiento y síntomas cardiovasculares como palpitaciones, taquicardia, dolor precordial e hipertensión arterial. También se presentan síntomas gastrointestinales como sensación de hambre, vómito y, ocasionalmente, dolor epigástrico.

    A diferencia de los gastrinomas, estos tumores rara vez se asocian con la adenomatosis múltiple endocrina (MEA: probablemente est

  6. EMC of Electrical Systems - Electromagnetic Coupling ( Part II

    Directory of Open Access Journals (Sweden)

    KOVACOVA, I.

    2007-04-01

    Full Text Available The paper deals with the general analysis of one part of the electromagnetic compatibility (EMC problem - the electromagnetic coupling applied in the field of power electrical systems. The verification simulation analyses and practical measurements of the electromagnetic coupling, which are confirming the correctness of results obtained from theoretical analyses (part I., are presented in part II. So they can be used for predictive stating of EMC quality of individual new electrotechnical products.

  7. Neutral Site Planning Project, Final Report. Volume II: Neighborhood Profiles.

    Science.gov (United States)

    Providence School Dept., RI.

    As part of a plan for the development of neutral site magnet schools in Providence, twenty-four individual neighborhoods are profiled in a series of charts and tables which provide demographic, economic, housing, and social service and crime data. The information provided includes ethnic composition, age breakdowns, educational level, income,…

  8. Recent Economic Perspectives on Political Economy, Part II.

    Science.gov (United States)

    Dewan, Torun; Shepsle, Kenneth A

    2008-07-01

    In recent years some of the best theoretical work on the political economy of political institutions and processes has begun surfacing outside the political science mainstream in high quality economics journals. This two-part paper surveys these contributions from a recent five-year period. In Part I, the focus is on elections, voting and information aggregation, followed by treatments of parties, candidates, and coalitions. In Part II, papers on economic performance and redistribution, constitutional design, and incentives, institutions, and the quality of political elites are discussed. Part II concludes with a discussion of the methodological bases common to economics and political science, the way economists have used political science research, and some new themes and arbitrage opportunities.

  9. Recent Economic Perspectives on Political Economy, Part II*

    Science.gov (United States)

    Dewan, Torun; Shepsle, Kenneth A.

    2013-01-01

    In recent years some of the best theoretical work on the political economy of political institutions and processes has begun surfacing outside the political science mainstream in high quality economics journals. This two-part paper surveys these contributions from a recent five-year period. In Part I, the focus is on elections, voting and information aggregation, followed by treatments of parties, candidates, and coalitions. In Part II, papers on economic performance and redistribution, constitutional design, and incentives, institutions, and the quality of political elites are discussed. Part II concludes with a discussion of the methodological bases common to economics and political science, the way economists have used political science research, and some new themes and arbitrage opportunities. PMID:23606754

  10. Acute dental pain, Part II: Diagnosis and emergency treatment.

    Science.gov (United States)

    Antonelli, J R

    1990-09-01

    Part II of this two-part series differentiates and explores endodontic-related emergencies with reversible and irreversible pulpitis. Indications and contra-indications for vital pulp therapy are explained, and treatment is outlined. The inflammatory process involved in irreversible pulpal disease is summarized, and the clinical signs, symptoms, and treatment of irreversible pulpitis (with and without acute periradicular involvement, with pulp necrosis, and acute periradicular abscess with and without cellulitis) are discussed.

  11. Performing arts medicine--instrumentalist musicians, Part II--examination.

    Science.gov (United States)

    Dommerholt, Jan

    2010-01-01

    Part I of this article's series included background information on performing arts medicine with a special focus on musicians. It covered in detail what questions need to be included in the history, when healthcare providers first examine musicians. In part II of the series, the emphasis is on the physical examination, including posture, range of motion and hypermobility, ergonomics, and instrument-specific examination procedures. The final article in the series will describe three case histories of musicians with hand pain.

  12. Methods of humidity determination Part II: Determination of material humidity

    OpenAIRE

    Rübner, Katrin; Balköse, Devrim; Robens, E.

    2008-01-01

    Part II covers the most common methods of measuring the humidity of solid material. State of water near solid surfaces, gravimetric measurement of material humidity, measurement of water sorption isotherms, chemical methods for determination of water content, measurement of material humidity via the gas phase, standardisation, cosmonautical observations are reviewed.

  13. Temperature profiles from XBT casts from the ATLANTIS II and other platforms as part of the International Decade of Ocean Exploration / International Ocean Studies / First Dynamic Response and Kinematics Experiment in the Drake Passage (IDOE/ISOS/FDRAKE) from 1980-09-17 to 1982-12-10 (NODC Accession 8300003)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the ATLANTIS II and other platforms from 17 September 1980 to 10 December 1982. Data were collected by Woods...

  14. Oceanographic station, temperature profile, meteorological, and other data from CTD and XBT casts from NOAA Ship DELAWARE II and other platforms as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1980-06-25 to 1983-08-04 (NODC Accession 8300119)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Oceanographic station, temperature profile, meteorological, and other data were collected from CTD and XBT casts from NOAA Ship DELAWARE II and other platforms from...

  15. Oceanographic Station, temperature profiles, and other data from CTD, XBT, and bottle casts from NOAA Ship DELAWARE II as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) from 1972-07-01 to 1972-08-13 (NODC Accession 7201299)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Oceanographic Station,temperature profiles, and other data were collected from CTD, XBT, and bottle casts from NOAA Ship DELAWARE II from 01 July 1972 to 13 August...

  16. Oceanographic station, temperature profiles, meteorological, and other data from XBT and bottle casts from NOAA Ship OREGON II as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1972-07-13 to 1972-08-08 (NODC Accession 7300271)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Oceanographic station, temperature profiles, meteorological, and other data were collected from bottle and XBT casts from NOAA Ship OREGON II from 13 July 1972 to 08...

  17. Ripening and storage conditions of Chétoui and Arbequina olives: Part II. Effect on olive endogenous enzymes and virgin olive oil secoiridoid profile determined by high resolution mass spectrometry.

    Science.gov (United States)

    Hachicha Hbaieb, Rim; Kotti, Faten; Cortes-Francisco, Nuria; Caixach, Josep; Gargouri, Mohamed; Vichi, Stefania

    2016-11-01

    Several factors affect virgin olive oil (VOO) phenolic profile. The aim of this study was to monitor olive hydrolytic (β-glucosidase) and oxidative (peroxydase, POX, and polyphenoloxydase, PPO) enzymes during olive ripening and storage and to determine their capacity to shape VOO phenolic profile. To this end, olives from the cultivars Chétoui and Arbequina were stored at 4°C or 25°C for 4weeks and their enzymatic activities and oil phenolic profiles were compared to those of ripening olives. We observed different trends in enzymes activities according to cultivar and storage temperature. Secoiridoid compounds, determined by high resolution mass spectrometry (HRMS), and their deacetoxylated, oxygenated, and deacetoxy-oxygenated derivatives were identified and their contents differed between the cultivars according to olive ripening degree and storage conditions. These differences could be due to β-glucosidase, POX and PPO activities changes during olive ripening and storage. Results also show that oxidised phenolic compounds could be a marker of VOO ''freshness". Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. Profile structures of TJ-II stellarator plasmas

    Science.gov (United States)

    Herranz; Pastor; Castejon; de La Luna E; Garcia-Cortes; Barth; Ascasibar; Sanchez; Tribaldos

    2000-11-27

    Fine structures are found in the TJ-II stellarator electron temperature and density profiles, when they are measured using a high spatial resolution Thomson scattering system. These structures consist of peaks and valleys superimposed to a smooth average. Some irregularities remain in an ensemble average of discharges with similar macroscopic parameters such as line density, central temperature, and plasma current. They are found in all the magnetic configurations explored in plasmas heated by electron cyclotron waves. Their characteristics are shown and their possible origin is discussed.

  19. HERBICIDAS INIBIDORES DO FOTOSSISTEMA IIPARTE I /\tPHOTOSYSTEM II INHIBITOR HERBICIDES - PART I

    Directory of Open Access Journals (Sweden)

    ILCA P. DE F. E SILVA

    2013-11-01

    Full Text Available O controle químico tem sido o mais utilizado em grandes áreas de plantio, principalmente por ser um método rápido e eficiente. Os herbicidas inibidores do fotossistema II (PSII são fundamentais para o manejo integrado de plantas daninhas e práticas conservacionista de solo. A aplicação é realizada em pré-emergência ou pós-emergência inicial das plantas daninhas. A absorção é pelas raízes, tendo como barreira as estrias de Caspari, sendo a translocação realizada pelo xilema. O processo de absorção e translocação também são dependentes das próprias características do produto, como as propriedades lipofílicas e hidrofílicas, as quais podem ser medidas através do coeficiente de partição octanol-água (Kow. A inibição da fotossíntese acontece pela ligação dos herbicidas deste grupo ao sítio de ligação da QB, na proteína D1 do fotossistema II, o qual se localiza na membrana dos tilacóides dos cloroplastos, causando, o bloqueia do transporte de elétrons da QA para QB, interrompendo a fixação do CO2 e a produção de ATP e NAPH2.

  20. A part-time Level II fieldwork program.

    Science.gov (United States)

    Adelstein, L A; Cohn, E S; Baker, R C; Barnes, M A

    1990-01-01

    This paper describes an alternative to the traditional Level II fieldwork program for master's degree students in occupational therapy. In this part-time 9-month program, students complete the fieldwork requirement while simultaneously balancing academic responsibilities. One advantage of this program over the traditional 3-month program is that the extended length of time offers students the opportunity to develop clinical skills beyond the technical level.

  1. Treatment of cellulite: Part II. Advances and controversies.

    Science.gov (United States)

    Khan, Misbah H; Victor, Frank; Rao, Babar; Sadick, Neil S

    2010-03-01

    Treatments for localized adiposities range from topical creams to liposuction. Most treatments lack a substantial proof of efficacy. The unpredictable treatment outcome can be related to the fact that cellulite adipose tissue is physiologically and biochemically different from subcutaneous tissue found elsewhere in the body. Part II of this two-part series on cellulite reviews the various treatment options that are currently available for human adipose tissue including, but not limited to, cellulite. It also focuses on newer techniques that can be potentially useful in the future for the treatment of cellulite. Copyright 2010 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.

  2. Forced Marriage-Culture or Crime? Part II

    OpenAIRE

    TAPP, David; JENKINSON, Susan

    2013-01-01

    This is Part II of the series.\\ud \\ud ‘Marriage shall be entered into only with the free and full consent of the intending spouses .’ \\ud \\ud It is important to begin by acknowledging the above statement, which is part of Article 16(2) of the Universal Declaration of Human Rights and also to distinguish between an arranged marriage and a forced marriage. \\ud \\ud An arranged marriage is ‘a marriage planned and agreed by the families or guardians of the couple concerned ’, while a forced marria...

  3. SURFACE BRIGHTNESS PROFILES OF DWARF GALAXIES. II. COLOR TRENDS AND MASS PROFILES

    Energy Technology Data Exchange (ETDEWEB)

    Herrmann, Kimberly A. [Penn State Mont Alto, 1 Campus Drive, Mont Alto, PA 17237 (United States); Hunter, Deidre A. [Lowell Observatory, 1400 West Mars Hill Road, Flagstaff, AZ 86001 (United States); Elmegreen, Bruce G., E-mail: kah259@psu.edu, E-mail: dah@lowell.edu, E-mail: bge@us.ibm.com [IBM T. J. Watson Research Center, 1101 Kitchawan Road, Yorktown Heights, NY 10598 (United States)

    2016-06-01

    In this second paper of a series, we explore the B  −  V , U  −  B , and FUV−NUV radial color trends from a multi-wavelength sample of 141 dwarf disk galaxies. Like spirals, dwarf galaxies have three types of radial surface brightness profiles: (I) single exponential throughout the observed extent (the minority), (II) down-bending (the majority), and (III) up-bending. We find that the colors of (1) Type I dwarfs generally become redder with increasing radius, unlike spirals which have a blueing trend that flattens beyond ∼1.5 disk scale lengths, (2) Type II dwarfs come in six different “flavors,” one of which mimics the “U” shape of spirals, and (3) Type III dwarfs have a stretched “S” shape where the central colors are flattish, become steeply redder toward the surface brightness break, then remain roughly constant beyond, which is similar to spiral Type III color profiles, but without the central outward bluing. Faint (−9 >  M{sub B}  > −14) Type II dwarfs tend to have continuously red or “U” shaped colors and steeper color slopes than bright (−14 >  M{sub B}  > −19) Type II dwarfs, which additionally have colors that become bluer or remain constant with increasing radius. Sm dwarfs and BCDs tend to have at least some blue and red radial color trend, respectively. Additionally, we determine stellar surface mass density (Σ) profiles and use them to show that the break in Σ generally remains in Type II dwarfs (unlike Type II spirals) but generally disappears in Type III dwarfs (unlike Type III spirals). Moreover, the break in Σ is strong, intermediate, and weak in faint dwarfs, bright dwarfs, and spirals, respectively, indicating that Σ may straighten with increasing galaxy mass. Finally, the average stellar surface mass density at the surface brightness break is roughly 1−2  M {sub ⊙} pc{sup −2} for Type II dwarfs but higher at 5.9  M {sub ⊙} pc{sup −2} or 27  M {sub ⊙} pc{sup −2} for

  4. Structure Learning and Statistical Estimation in Distribution Networks - Part II

    Energy Technology Data Exchange (ETDEWEB)

    Deka, Deepjyoti [Univ. of Texas, Austin, TX (United States); Backhaus, Scott N. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Chertkov, Michael [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-02-13

    Limited placement of real-time monitoring devices in the distribution grid, recent trends notwithstanding, has prevented the easy implementation of demand-response and other smart grid applications. Part I of this paper discusses the problem of learning the operational structure of the grid from nodal voltage measurements. In this work (Part II), the learning of the operational radial structure is coupled with the problem of estimating nodal consumption statistics and inferring the line parameters in the grid. Based on a Linear-Coupled(LC) approximation of AC power flows equations, polynomial time algorithms are designed to identify the structure and estimate nodal load characteristics and/or line parameters in the grid using the available nodal voltage measurements. Then the structure learning algorithm is extended to cases with missing data, where available observations are limited to a fraction of the grid nodes. The efficacy of the presented algorithms are demonstrated through simulations on several distribution test cases.

  5. [The Mexican consensus on gastroesophageal reflux disease. Part II].

    Science.gov (United States)

    Huerta-Iga, F; Tamayo-de la Cuesta, J L; Noble-Lugo, A; Hernández-Guerrero, A; Torres-Villalobos, G; Ramos-de la Medina, A; Pantoja-Millán, J P

    2013-01-01

    To update the themes of endoscopic and surgical treatment of Gastroesophageal Reflux Disease (GERD) from the Mexican Consensus published in 2002. Part I of the 2011 Consensus dealt with the general concepts, diagnosis, and medical treatment of this disease. Part II covers the topics of the endoscopic and surgical treatment of GERD. In this second part, an expert in endoscopy and an expert in GERD surgery, along with the three general coordinators of the consensus, carried out an extensive bibliographic review using the Embase, Cochrane, and Medline databases. Statements referring to the main aspects of endoscopic and surgical treatment of this disease were elaborated and submitted to specialists for their consideration and vote, utilizing the modified Delphi method. The statements were accepted into the consensus if the level of agreement was 67% or higher. Twenty-five statements corresponding to the endoscopic and surgical treatment of GERD resulted from the voting process, and they are presented herein as Part II of the consensus. The majority of the statements had an average level of agreement approaching 90%. Currently, endoscopic treatment of GERD should not be regarded as an option, given that the clinical results at 3 and 5 years have not demonstrated durability or sustained symptom remission. The surgical indications for GERD are well established; only those patients meeting the full criteria should be candidates and their surgery should be performed by experts. Copyright © 2012 Asociación Mexicana de Gastroenterología. Published by Masson Doyma México S.A. All rights reserved.

  6. PREREM: an interactive data preprocessing code for INREM II. Part I: user's manual. Part II: code structure

    Energy Technology Data Exchange (ETDEWEB)

    Ryan, M.T.; Fields, D.E.

    1981-05-01

    PREREM is an interactive computer code developed as a data preprocessor for the INREM-II (Killough, Dunning, and Pleasant, 1978a) internal dose program. PREREM is intended to provide easy access to current and self-consistent nuclear decay and radionuclide-specific metabolic data sets. Provision is made for revision of metabolic data, and the code is intended for both production and research applications. Documentation for the code is in two parts. Part I is a user's manual which emphasizes interpretation of program prompts and choice of user input. Part II stresses internal structure and flow of program control and is intended to assist the researcher who wishes to revise or modify the code or add to its capabilities. PREREM is written for execution on a Digital Equipment Corporation PDP-10 System and much of the code will require revision before it can be run on other machines. The source program length is 950 lines (116 blocks) and computer core required for execution is 212 K bytes. The user must also have sufficient file space for metabolic and S-factor data sets. Further, 64 100 K byte blocks of computer storage space are required for the nuclear decay data file. Computer storage space must also be available for any output files produced during the PREREM execution. 9 refs., 8 tabs.

  7. Blade System Design Study. Part II, final project report (GEC).

    Energy Technology Data Exchange (ETDEWEB)

    Griffin, Dayton A. (DNV Global Energy Concepts Inc., Seattle, WA)

    2009-05-01

    As part of the U.S. Department of Energy's Low Wind Speed Turbine program, Global Energy Concepts LLC (GEC)1 has studied alternative composite materials for wind turbine blades in the multi-megawatt size range. This work in one of the Blade System Design Studies (BSDS) funded through Sandia National Laboratories. The BSDS program was conducted in two phases. In the Part I BSDS, GEC assessed candidate innovations in composite materials, manufacturing processes, and structural configurations. GEC also made recommendations for testing composite coupons, details, assemblies, and blade substructures to be carried out in the Part II study (BSDS-II). The BSDS-II contract period began in May 2003, and testing was initiated in June 2004. The current report summarizes the results from the BSDS-II test program. Composite materials evaluated include carbon fiber in both pre-impregnated and vacuum-assisted resin transfer molding (VARTM) forms. Initial thin-coupon static testing included a wide range of parameters, including variation in manufacturer, fiber tow size, fabric architecture, and resin type. A smaller set of these materials and process types was also evaluated in thin-coupon fatigue testing, and in ply-drop and ply-transition panels. The majority of materials used epoxy resin, with vinyl ester (VE) resin also used for selected cases. Late in the project, testing of unidirectional fiberglass was added to provide an updated baseline against which to evaluate the carbon material performance. Numerous unidirectional carbon fabrics were considered for evaluation with VARTM infusion. All but one fabric style considered suffered either from poor infusibility or waviness of fibers combined with poor compaction. The exception was a triaxial carbon-fiberglass fabric produced by SAERTEX. This fabric became the primary choice for infused articles throughout the test program. The generally positive results obtained in this program for the SAERTEX material have led to its

  8. Calculated resonance line profiles of [Mg II], [C II], and [Si IV] in the solar atmosphere

    Energy Technology Data Exchange (ETDEWEB)

    Avrett, E.; McKillop, S. [Smithsonian Astrophysical Observatory, 60 Garden Street, Cambridge, MA 02138 (United States); Landi, E. [Department of Atmospheric, Oceanic and Space Sciences, University of Michigan, Ann Arbor, MI 48109 (United States)

    2013-12-20

    NASA's Interface Region Imaging Spectrograph space mission, launched 2013 June 27, is intended to study the structure of the solar chromosphere and the transition region between the chromosphere and corona. The spectral lines to be observed include the Mg II k line at 2796.5 Å, the C II 1334.5 Å line, and the Si IV line at 1393.8 Å, which are formed in the middle chromosphere, the upper chromosphere, and the lower transition region, respectively. Here we calculate the profiles of these lines from four models of the solar atmosphere, intended to represent the faint and mean internetwork, a network lane, and bright network. We show how the profiles change from the center of the solar disk toward the limb of the Sun and in response to outflows and inflows. These results are intended to cover the range of expected quiet-Sun observations and assist in their interpretation. We expect that the observations will lead to improvements in the models, which can then be used to estimate the required non-radiative heating in the different regions.

  9. 46 CFR Appendix II to Part 150 - Explanation of Figure 1

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Explanation of Figure 1 II Appendix II to Part 150... COMPATIBILITY OF CARGOES Pt. 150, App. II Appendix II to Part 150—Explanation of Figure 1 Definition of a... referenced by a footnote which indicates that exceptions exist and are listed in Appendix I. Unless the...

  10. 29 CFR Appendix II to Part 1918 - Tables for Selected Miscellaneous Auxiliary Gear (Mandatory)

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Tables for Selected Miscellaneous Auxiliary Gear (Mandatory) II Appendix II to Part 1918 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND.... 1918, App. II Appendix II to Part 1918—Tables for Selected Miscellaneous Auxiliary Gear (Mandatory...

  11. Hysterosalpingographic Appearances of Female Genital Tract Tuberculosis: Part II: Uterus

    Directory of Open Access Journals (Sweden)

    Firoozeh Ahmadi

    2014-03-01

    Full Text Available Female genital tuberculosis remains as a major cause of tubal obstruction leading to infertility, especially in developing countries. The global prevalence of genital tuberculosis has increased during the past two decades due to increasing acquired immunodeficiency syndrome. Genital tuberculosis (TB is commonly asymptomatic and it is diagnosed during infertility investigations. Despite of recent advances in imaging tools such as computed tomography (CT scan, magnetic resonance imaging (MRI and ultrasongraphy, hysterosalpingography has been considered as the standard screening test for evaluation of tubal infertility and as a valuable tool for diagnosis of female genital tuberculosis. Tuberculosis gives rise to various appearances on hysterosalpingography (HSG from non-specific changes to specific findings. The present pictorial review illustrates and describes specific and non-specific radiographic features of female genital tuberculosis in two parts. Part I presents specific findings of tuberculosis related to tubes such as "beaded tube", "golf club tube", "pipestem tube", "cobble stone tube" and the "leopard skin tube". Part II will describe adverse effects of tuberculosis on structure of endometrium and radiological specific findings, such as "T-shaped" tuberculosis uterus, "pseudo-unicornuate "uterus, "collar-stud abscess" and "dwarfed" uterus with lymphatic intravasation and occluded tubes which have not been encountered in the majority of non-tuberculosis cases.

  12. Impedance-Source Networks for Electric Power Conversion Part II

    DEFF Research Database (Denmark)

    Siwakoti, Yam P.; Peng, Fang Zheng; Blaabjerg, Frede

    2015-01-01

    -based power converters has been covered in a previous paper and main topologies were discussed from an application point of view. Now Part II provides a comprehensive review of the most popular control and modulation strategies for impedance-source network-based power converters/inverters. These methods...... are compared in terms of theoretical complexity and performance, when applied to the respective switching topologies. Further, this paper provides as a guide and quick reference for researchers and practicing engineers in deciding which control and modulation method to consider for an application in a given......Impedance-source networks cover the entire spectrum of electric power conversion applications (dc-dc, dc-ac, ac-dc, ac-ac) controlled and modulated by different modulation strategies to generate the desired dc or ac voltage and current at the output. A comprehensive review of various impedance-source-network...

  13. Lipid Profile in Different Parts of Edible Jellyfish Rhopilema esculentum.

    Science.gov (United States)

    Zhu, Si; Ye, Mengwei; Xu, Jilin; Guo, Chunyang; Zheng, Huakun; Hu, Jiabao; Chen, Juanjuan; Wang, Yajun; Xu, Shanliang; Yan, Xiaojun

    2015-09-23

    Jellyfish Rhopilema esculentum has been exploited commercially as a delicious food for a long time. Although the edible and medicinal values of R. esculentum have gained extensive attention, the effects of lipids on its nutritional value have rarely been reported. In the present of study, the lipid profile including lipid classes, fatty acyl compositions, and fatty acid (FA) positions in lipids from different parts (oral arms, umbrella, and mouth stalk) of R. esculentum was explored by ultraperformance liquid chromatography--electrospray ionization--quadrupole time-of-flight mass spectrometry (UPLC-ESI-Q-TOF-MS). More than 87 species from 10 major lipid classes including phosphatidylcholine (PC), lysophosphatidylcholine (LPC), phosphatidylethanolamine (PE), lysophosphatidylethanolamine (LPE), phosphatidylinositol (PI), lysophosphatidylinositol (LPI), phosphatidylserine (PS), ceramide (Cer), ceramide 2-aminoethylphosphonate (CAEP), and triacylglycerol (TAG) were separated and characterized. Semiquantification of individual lipid species in different parts of R. esculentum was also conducted. Results showed that glycerophospholipids (GPLs) enriched in highly unsaturated fatty acids (HUFAs) were the major compenents in all parts of R. esculentum, which accounted for 54-63% of total lipids (TLs). Considering the high level of GPLs and the FA compositions in GPLs, jellyfish R. esculentum might have great potential as a health-promoting food for humans and as a growth-promoting diet for some commercial fish and crustaceans. Meanwhile, LPC, LPE, and LPI showed high levels in oral arms when compared with umbrella and mouth stalk, which may be due to the high proportion of phospholipase A2 (PLA2) in oral arms. Moreover, a high CAEP level was detected in oral arms, which may render cell membranes with resistance to chemical hydrolysis by PLA2. The relatively low TAG content could be associated with specific functions of oral arms.

  14. How to bend galaxy disc profiles - II. Stars surfing the bar in Type-III discs

    Science.gov (United States)

    Herpich, J.; Stinson, G. S.; Rix, H.-W.; Martig, M.; Dutton, A. A.

    2017-10-01

    The radial profiles of stars in disc galaxies are observed to be either purely exponential (Type-I), truncated (Type-II) or antitruncated (Type-III) exponentials. Controlled formation simulations of isolated galaxies can reproduce all of these profile types by varying a single parameter, the initial halo spin. In this paper, we examine these simulations in more detail in an effort to identify the physical mechanism that leads to the formation of Type-III profiles. The stars in the antitruncated outskirts of such discs are now on eccentric orbits, but were born on near-circular orbits at much smaller radii. We show that, and explain how, they were driven to the outskirts via non-linear interactions with a strong and long-lived central bar, which greatly boosted their semimajor axis but also their eccentricity. While bars have been known to cause radial heating and outward migration to stellar orbits, we link this effect to the formation of Type-III profiles. This predicts that the antitruncated parts of galaxies have unusual kinematics for disc-like stellar configurations: high radial velocity dispersions and slow net rotation. Whether such discs exist in nature, can be tested by future observations.

  15. Digital Assays Part II: Digital Protein and Cell Assays.

    Science.gov (United States)

    Basu, Amar S

    2017-08-01

    A digital assay is one in which the sample is partitioned into many containers such that each partition contains a discrete number of biological entities (0, 1, 2, 3, . . .). A powerful technique in the biologist's toolkit, digital assays bring a new level of precision in quantifying nucleic acids, measuring proteins and their enzymatic activity, and probing single-cell genotype and phenotype. Where part I of this review focused on the fundamentals of partitioning and digital PCR, part II turns its attention to digital protein and cell assays. Digital enzyme assays measure the kinetics of single proteins with enzymatic activity. Digital enzyme-linked immunoassays (ELISAs) quantify antigenic proteins with 2 to 3 log lower detection limit than conventional ELISA, making them well suited for low-abundance biomarkers. Digital cell assays probe single-cell genotype and phenotype, including gene expression, intracellular and surface proteins, metabolic activity, cytotoxicity, and transcriptomes (scRNA-seq). These methods exploit partitioning to 1) isolate single cells or proteins, 2) detect their activity via enzymatic amplification, and 3) tag them individually by coencapsulating them with molecular barcodes. When scaled, digital assays reveal stochastic differences between proteins or cells within a population, a key to understanding biological heterogeneity. This review is intended to give a broad perspective to scientists interested in adopting digital assays into their workflows.

  16. Reforming Science Education: Part II. Utilizing Kieran Egan's Educational Metatheory

    Science.gov (United States)

    Schulz, Roland M.

    2009-04-01

    This paper is the second of two parts and continues the conversation which had called for a shift in the conceptual focus of science education towards philosophy of education, with the requirement to develop a discipline-specific “philosophy” of science education. In Part I, conflicting conceptions of science literacy were identified with disparate “visions” tied to competing research programs as well as school-based curricular paradigms. The impasse in the goals of science education and thereto, the contending views of science literacy, were themselves associated with three underlying fundamental aims of education (knowledge-itself; personal development; socialization) which, it was argued, usually undercut the potential of each other. During periods of “crisis-talk” and throughout science educational history these three aims have repeatedly attempted to assert themselves. The inability of science education research to affect long-term change in classrooms was correlated not only to the failure to reach a consensus on the aims (due to competing programs and to the educational ideologies of their social groups), but especially to the failure of developing true educational theories (largely neglected since Hirst). Such theories, especially metatheories, could serve to reinforce science education’s growing sense of academic autonomy and independence from socio-economic demands. In Part II, I offer as a suggestion Egan’s cultural-linguistic theory as a metatheory to help resolve the impasse. I hope to make reformers familiar with his important ideas in general, and more specifically, to show how they can complement HPS rationales and reinforce the work of those researchers who have emphasized the value of narrative in learning science.

  17. Recovery in soccer : part ii-recovery strategies.

    Science.gov (United States)

    Nédélec, Mathieu; McCall, Alan; Carling, Chris; Legall, Franck; Berthoin, Serge; Dupont, Gregory

    2013-01-01

    In the formerly published part I of this two-part review, we examined fatigue after soccer matchplay and recovery kinetics of physical performance, and cognitive, subjective and biological markers. To reduce the magnitude of fatigue and to accelerate the time to fully recover after completion, several recovery strategies are now used in professional soccer teams. During congested fixture schedules, recovery strategies are highly required to alleviate post-match fatigue, and then to regain performance faster and reduce the risk of injury. Fatigue following competition is multifactorial and mainly related to dehydration, glycogen depletion, muscle damage and mental fatigue. Recovery strategies should consequently be targeted against the major causes of fatigue. Strategies reviewed in part II of this article were nutritional intake, cold water immersion, sleeping, active recovery, stretching, compression garments, massage and electrical stimulation. Some strategies such as hydration, diet and sleep are effective in their ability to counteract the fatigue mechanisms. Providing milk drinks to players at the end of competition and a meal containing high-glycaemic index carbohydrate and protein within the hour following the match are effective in replenishing substrate stores and optimizing muscle-damage repair. Sleep is an essential part of recovery management. Sleep disturbance after a match is common and can negatively impact on the recovery process. Cold water immersion is effective during acute periods of match congestion in order to regain performance levels faster and repress the acute inflammatory process. Scientific evidence for other strategies reviewed in their ability to accelerate the return to the initial level of performance is still lacking. These include active recovery, stretching, compression garments, massage and electrical stimulation. While this does not mean that these strategies do not aid the recovery process, the protocols implemented up until

  18. Part II--Management of pediatric post-traumatic headaches.

    Science.gov (United States)

    Pinchefsky, Elana; Dubrovsky, Alexander Sasha; Friedman, Debbie; Shevell, Michael

    2015-03-01

    Post-traumatic headache is one of the most common symptoms occurring after mild traumatic brain injury in children. This is an expert opinion-based two-part review on pediatric post-traumatic headaches. In part II, we focus on the medical management of post-traumatic headaches. There are no randomized controlled trials evaluating the efficacy of therapies specifically for pediatric post-traumatic headaches. Thus, the algorithm we propose has been extrapolated from the primary headache literature and small noncontrolled trials of post-traumatic headache. Most post-traumatic headaches are migraine or tension type, and standard medications for these headache types are used. A multifaceted approach is needed to address all the possible causes of headache and any comorbid conditions that may delay recovery or alter treatment choices. For acute treatment, nonsteroidal anti-inflammatories can be used. If the headaches have migrainous features and nonsteroidal anti-inflammatories are not effective, triptans may be beneficial. Opioids are not indicated. Medication overuse should be avoided. For preventive treatments, some reports indicate that amitriptyline, gabapentin, or topiramate may be beneficial. Amitriptyline is a good choice because it can be used to treat both migraine and tension-type headaches. Nerve blocks, nutraceuticals (e.g. melatonin), and behavioral therapies may also be useful, and lifestyle factors, especially adequate sleep hygiene and strategies to cope with anxiety, should be emphasized. Improved treatment of acute post-traumatic headache may reduce the likelihood of developing chronic headaches, which can be especially problematic to effectively manage and can be functionally debilitating. Copyright © 2015 Elsevier Inc. All rights reserved.

  19. Autism and EMF? Plausibility of a pathophysiological link part II.

    Science.gov (United States)

    Herbert, Martha R; Sage, Cindy

    2013-06-01

    Autism spectrum conditions (ASCs) are defined behaviorally, but they also involve multileveled disturbances of underlying biology that find striking parallels in the physiological impacts of electromagnetic frequency and radiofrequency radiation exposures (EMF/RFR). Part I (Vol 776) of this paper reviewed the critical contributions pathophysiology may make to the etiology, pathogenesis and ongoing generation of behaviors currently defined as being core features of ASCs. We reviewed pathophysiological damage to core cellular processes that are associated both with ASCs and with biological effects of EMF/RFR exposures that contribute to chronically disrupted homeostasis. Many studies of people with ASCs have identified oxidative stress and evidence of free radical damage, cellular stress proteins, and deficiencies of antioxidants such as glutathione. Elevated intracellular calcium in ASCs may be due to genetics or may be downstream of inflammation or environmental exposures. Cell membrane lipids may be peroxidized, mitochondria may be dysfunctional, and various kinds of immune system disturbances are common. Brain oxidative stress and inflammation as well as measures consistent with blood-brain barrier and brain perfusion compromise have been documented. Part II of this paper documents how behaviors in ASCs may emerge from alterations of electrophysiological oscillatory synchronization, how EMF/RFR could contribute to these by de-tuning the organism, and policy implications of these vulnerabilities. It details evidence for mitochondrial dysfunction, immune system dysregulation, neuroinflammation and brain blood flow alterations, altered electrophysiology, disruption of electromagnetic signaling, synchrony, and sensory processing, de-tuning of the brain and organism, with autistic behaviors as emergent properties emanating from this pathophysiology. Changes in brain and autonomic nervous system electrophysiological function and sensory processing predominate, seizures

  20. Discovery of Quantum structure and A Theory of Everything Part I and Part II

    Science.gov (United States)

    Zhang, Meggie

    2012-10-01

    (Part I) During my research I discovered logical errors in the logic of science and in mathematics. These errors caused scientists missed out important information when interpreting data. This led me to revisit the method of science and the existing results and able to find new information, which lead to the discovery of photon's structure. A ``particle collision illumination'' experiment then provided direct evidence supported the structure. Analysis of the properties of the structure suggested an organized but not-continuous multi-dimension (n-D) space within. Therefore I formed a hypothesis of a not-continuous n-D space structure. In search for evidence, I turned into crystal technology, and found direct evidence supported the hypotesis, then further particle collision found more evidence support this finding. (Part II) Analysis of single electron buildup revealed star and galaxy formation is from a single particle following a predictable pattern. This pattern is also common in matter formation. Analysis of the quantum structure suggested the formation of a larger structure through the space expansion within the structure. Further experiment results support the finding and result revealed the expansion is through space folding. Result also suggested a violation of energy conservation law that energy is created during the formation of matter, and matter itself is moving from a lower energy state to a higher energy state. When putting all information together, I arrived to a theory of everything which gives explanations to all existing phenomenon in the universe including black hole, dark energy, star formation, consciousness.

  1. On the Use of the K-Chart for Phase II Monitoring of Simple Linear Profiles

    OpenAIRE

    Gani, Walid; Limam, Mohamed

    2013-01-01

    Control charts for monitoring linear profiles are used to control quality processes which are characterized by a relationship between a response variable and one or more explanatory variables. In the literature, the majority of control charts deal with phase II analysis of linear profiles, where the objective is to assess the performance of control charts in detecting shifts in the parameters of linear profiles. Recently, the kernel distance-based multivariate control chart, also known as the...

  2. Psychiatric emergencies (part II): psychiatric disorders coexisting with organic diseases.

    Science.gov (United States)

    Testa, A; Giannuzzi, R; Sollazzo, F; Petrongolo, L; Bernardini, L; Dain, S

    2013-02-01

    In this Part II psychiatric disorders coexisting with organic diseases are discussed. "Comorbidity phenomenon" defines the not univocal interrelation between medical illnesses and psychiatric disorders, each other negatively influencing morbidity and mortality. Most severe psychiatric disorders, such as schizophrenia, bipolar disorder and depression, show increased prevalence of cardiovascular disease, related to poverty, use of psychotropic medication, and higher rate of preventable risk factors such as smoking, addiction, poor diet and lack of exercise. Moreover, psychiatric and organic disorders can develop together in different conditions of toxic substance and prescription drug use or abuse, especially in the emergency setting population. Different combinations with mutual interaction of psychiatric disorders and substance use disorders are defined by the so called "dual diagnosis". The hypotheses that attempt to explain the psychiatric disorders and substance abuse relationship are examined: (1) common risk factors; (2) psychiatric disorders precipitated by substance use; (3) psychiatric disorders precipitating substance use (self-medication hypothesis); and (4) synergistic interaction. Diagnostic and therapeutic difficulty concerning the problem of dual diagnosis, and legal implications, are also discussed. Substance induced psychiatric and organic symptoms can occur both in the intoxication and withdrawal state. Since ancient history, humans selected indigene psychotropic plants for recreational, medicinal, doping or spiritual purpose. After the isolation of active principles or their chemical synthesis, higher blood concentrations reached predispose to substance use, abuse and dependence. Abuse substances have specific molecular targets and very different acute mechanisms of action, mainly involving dopaminergic and serotoninergic systems, but finally converging on the brain's reward pathways, increasing dopamine in nucleus accumbens. The most common

  3. 40 CFR Appendix II to Part 600 - Sample Fuel Economy Calculations

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Sample Fuel Economy Calculations II... FUEL ECONOMY AND CARBON-RELATED EXHAUST EMISSIONS OF MOTOR VEHICLES Pt. 600, App. II Appendix II to Part 600—Sample Fuel Economy Calculations (a) This sample fuel economy calculation is applicable to...

  4. Individual Part Score Profiles of Children with Intellectual Disability: A Descriptive Analysis across Three Intelligence Tests

    Science.gov (United States)

    Bergeron, Renee; Floyd, Randy G.

    2013-01-01

    This study examined the group- and individual-level part score profiles of children with intellectual disability (ID) who participated in clinical validity studies supporting three individually administered intelligence tests. Across tests, children with ID produced group-level profiles comprising mean part scores that fell in the Low to Very Low…

  5. Thinking in Nursing Education. Part I: A Student's Experience in Learning To Think. Part II: A Teacher's Experience.

    Science.gov (United States)

    Ironside, Pamela Magnussen

    1999-01-01

    Part I describes a nursing student's experience learning to think in clinical practice, illustrating the need for a variety of approaches to critical thinking. Part II shows how nursing teachers and students are challenging conventional approaches and creating more responsive pedagogies. (SK)

  6. 10 CFR Appendix II to Part 504 - Fuel Price Computation

    Science.gov (United States)

    2010-01-01

    ... index for each fuel in year i. Pi=Price of fuel in year i. Po=Price of fuel in base year. EQ II-2 is..., and coal. It also contains annual inflation indices. These values were computed from information... delivered market price of the proposed fuel. PXi=The fuel price index value in year i, computed with...

  7. Complexometric determination, Part II: Complexometric determination of Cu2+-ions

    Directory of Open Access Journals (Sweden)

    Rajković Miloš B.

    2002-01-01

    Full Text Available A copper-selective electrode of the coated wire type based on sulphidized copper wire was applied successfully for determining Cu(II ions by complexometric titration with the disodium salt of EDTA (complexon III. By the formation of internal complex compounds with the Cu(II ion, the copper concentration in the solution decreases, and all this is followed by a change of potential of the indicator system Cu-DWISE (or Cu-EDWISE/SCE. At the terminal point of titration, when all the Cu(II ions are already utilized for the formation of the complex with EDTA, there occurs a steep rise of potential, thus enabling us, through the first or second derivative to note the quantity of copper that is present in the solution. Copper-selective electrode showed a responsivity towards titration with EDTA as a complexing agent, with the absence of "fatigue" due to a great number of repeated measurings. Errors occurring during quantitative measurements were more a characteristic of the overall procedure which involve, because of the impossibility of the complete absence of subjectivity, a constant error, and the reproducibility of the results confirmed this fact. The disodium salt of EDTA appeared as a very efficient titrant in all titrations and with various concentrations ot Cu(II ions in the solution, with somewhat weaker response at lower concentrations in the solution.

  8. Gene expression profiles in stages II and III colon cancers

    DEFF Research Database (Denmark)

    Thorsteinsson, Morten; Kirkeby, Lene T; Hansen, Raino

    2012-01-01

    PURPOSE: A 128-gene signature has been proposed to predict outcome in patients with stages II and III colorectal cancers. In the present study, we aimed to reproduce and validate the 128-gene signature in external and independent material. METHODS: Gene expression data from the original material...... were retrieved from the Gene Expression Omnibus (GEO) (n¿=¿111) in addition to a Danish data set (n¿=¿37). All patients had stages II and III colon cancers. A Prediction Analysis of Microarray classifier, based on the 128-gene signature and the original training set of stage I (n¿=¿65) and stage IV (n......¿=¿76) colon cancers, was reproduced. The stages II and III colon cancers were subsequently classified as either stage I-like (good prognosis) or stage IV-like (poor prognosis) and assessed by the 36 months cumulative incidence of relapse. RESULTS: In the GEO data set, results were reproducible in stage...

  9. Inteligencia Artificial y Neurología: II Parte

    Directory of Open Access Journals (Sweden)

    Mario Camacho Pinto

    1986-12-01

    Full Text Available

    Algunos comentarios sobre la primera parte me han inducido a ampliar las bases de este trabajo mediante la presentación de aspectos comunes y conceptos disímiles sobre la hipotética relación entre inteligencia artificial (lA e inteligencia humana(IH. El tema es tan complejo que un intento por resumirlo de por sí ya es atrayente además de necesario.

    Microhistoria de la lA. Ciñéndome a una cruda realidad la lA nació en la Conferencia de Darmouth, año 1956, cuando John McCarthy, profesor de ciencia de computador en Stanford Un. acuñó el término de lA. Sin embargo, especulando un poco podemos decir que cierta inquietud existió desde la antigüedad, mucho antes de los computadores y aún de la electrónica (1 cuando el ser humano irresistiblemente mostraba inquietud por crear I fuera del cerebro humano. Se encuentran algunos ejemplos en la Mitología griega: Hefestos. dios del fuego y de los metales, confeccionaba creaciones semihumanas en su forja. Pigmalión desencantado de las mujeres modeló su propia ninfa en mármol y para poder casarse con ella imploró suplicante hasta conseguir que Afrodita le diera vida.

    En la Europa medioeval al papa Silvestre II (apodado el hechicero por su sabiduría, año 909 D.C. se le atribuye que construía cabezas parlantes. En el siglo XVI Para celso clamó haber inventado un homúnculo. Y el rabino checo Jundo ben Loew esculpió un hombre en arcilla, José Golem, y lo constituyó espía en Praga. En 1854 el matemático británico George Boole propuso un sistema para describir lógica (2 -las leyes del pensamiento en términos matemáticos: “álgebra booliana”, “mathematical logics” que representa procesos lógicos con dos dígitos, 9 y 1.

    En 1937 Alan Turing demostró que una máquina binaria podía ser programada para realizar cualquier tarea algorítmica. Esta máquina de Turing sólo podía ejecutar dos acciones: dibujar y borrar. En el mismo año Claude

  10. Reforming Science Education: Part II. Utilizing Kieran Egan's Educational Metatheory

    Science.gov (United States)

    Schulz, Roland M.

    2009-01-01

    This paper is the second of two parts and continues the conversation which had called for a shift in the conceptual focus of science education towards philosophy of education, with the requirement to develop a discipline-specific "philosophy" of science education. In Part I, conflicting conceptions of science literacy were identified with…

  11. Mesenchymal tumours of the mediastinum—part II

    NARCIS (Netherlands)

    M.A. den Bakker (Michael); A. Marx (Alexander); K. Mukai (Kiyoshi); P. Ströbel (Philipp)

    2015-01-01

    textabstractThis is the second part of a two-part review on soft tissue tumours which may be encountered in the mediastinum. This review is based on the 2013 WHO classification of soft tissue tumours and the 2015 WHO classification of tumours of the lung, pleura, thymus and heart and provides an

  12. Flow resistance of textile materials. Part II: Multifilament Fabrics

    NARCIS (Netherlands)

    Gooijer, H.; Gooijer, H.; Warmoeskerken, Marinus; Groot Wassink, J.

    2003-01-01

    Part I of this series presented a new model for predicting the flow resistance of monofilament fabrics. In this part, the model is applied to the flow resistance of multi filament fabrics. Experiments show that flow resistance in multifilament fabrics can be modeled in general, but it appears that

  13. Profiles of aggression among psychiatric patients. II. Covariates and predictors.

    Science.gov (United States)

    Kay, S R; Wolkenfeld, F; Murrill, L M

    1988-09-01

    An Aggression Risk Profile was developed as an objective multidimensional scale for characterizing aggressive psychiatric patients and predicting verbal, physical, and general manifestations of aggression. Based on earlier studies, the 39-item Aggression Risk Profile incorporated demographic, diagnostic, historical, and clinical parameters. Its reliability, discriminative validity, and predictive validity were supported in its application to a total of 208 inpatients. Aggressive patients were more often found to be men, to be diagnosed with organic mental syndrome or substance abuse disorder, and to be notable in history of aggression. They tended to be angry and excitable but not more floridly ill than control subjects. The contemporaneous covariates of aggression, however, were not the same as the predictors, as determined by 3-month prospective follow-up. Twelve significant predictors were identified, and multiple regression analysis revealed different sets of measures that explain 45.0% to 52.5% of the variance for verbal, physical, and total aggression. The most reliable predictors were younger age, shorter length of illness, hostility, depression, anger, and difficulty in delaying gratification. We concluded that prediction is augmented by the combination of clinical and nonclinical predictors, and we discussed likely sources of disparity in previous research.

  14. Management Plan Parts I & II : Muscatatuck National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This is Parts 1 and 2 of the Muscatatuck NWR Management Plan. Background information about the Refuge is provided, followed by Refuge objectives and management...

  15. Dissolution Enhancement of Drugs. Part II: Effect of Carriers ...

    African Journals Online (AJOL)

    ... surfactants, in dissolution enhancement. This part describes the use of cyclodextrin, carbohydrates, hydrotropes, polyglocolized glycerides, dendrimers, acids and miscellaneous carriers in enhancing dissolution of drugs. Keywords: Dissolution enhancement; aqueous solubility, water soluble carriers; lipophilic, excipients.

  16. Guidelines for acute ischemic stroke treatment: part II: stroke treatment

    Directory of Open Access Journals (Sweden)

    Sheila Cristina Ouriques Martins

    2012-11-01

    Full Text Available The second part of these Guidelines covers the topics of antiplatelet, anticoagulant, and statin therapy in acute ischemic stroke, reperfusion therapy, and classification of Stroke Centers. Information on the classes and levels of evidence used in this guideline is provided in Part I. A translated version of the Guidelines is available from the Brazilian Stroke Society website (www.sbdcv.com.br.

  17. Expression Profiles of Cellular Retinol-binding Protein, Type II (CRBP II) in Erlang Mountainous Chickens.

    Science.gov (United States)

    Yin, H D; Tian, K; Li, D Y; Gilbert, E R; Xiao, L H; Chen, S Y; Wang, Y; Liu, Y P; Zhao, X L; Zhu, Q

    2014-03-01

    Cellular retinol-binding protein II (CRBP II) belongs to the family of cellular retinol-binding proteins and plays a major role in absorption, transport, and metabolism of vitamin A. In addition, because vitamin A is correlated with reproductive performance, we measured CRBP II mRNA abundance in erlang mountainous chickens by real-time PCR using the relative quantification method. The expression of CRBP II showed a tissue-specific pattern and egg production rate-dependent changes. The expression was very high (p<0.05) in jejunum and liver, intermediate in kidney, ovary, and oviduct, and lowest (p<0.05) in heart, hypothalamus, and pituitary. In the hypothalamus, oviduct, ovary, and pituitary, CRBP II mRNA abundance were correlated to egg production rate, which increased from 12 wk to 32 wk, peaked at 32 wk relative to the other time points, and then decreased from 32 wk to 45 wk. In contrast, the expression of CRBP II mRNA in heart, jejunum, kidney, and liver was not different at any of the ages evaluated in this study. These data may help to understand the genetic basis of vitamin A metabolism, and suggest that CRBP II may be a candidate gene to affect egg production traits in chickens.

  18. Expression Profiles of Cellular Retinol-binding Protein, Type II (CRBP II in Erlang Mountainous Chickens

    Directory of Open Access Journals (Sweden)

    H. D. Yin

    2014-03-01

    Full Text Available Cellular retinol-binding protein II (CRBP II belongs to the family of cellular retinol-binding proteins and plays a major role in absorption, transport, and metabolism of vitamin A. In addition, because vitamin A is correlated with reproductive performance, we measured CRBP II mRNA abundance in erlang mountainous chickens by real-time PCR using the relative quantification method. The expression of CRBP II showed a tissue-specific pattern and egg production rate-dependent changes. The expression was very high (p<0.05 in jejunum and liver, intermediate in kidney, ovary, and oviduct, and lowest (p<0.05 in heart, hypothalamus, and pituitary. In the hypothalamus, oviduct, ovary, and pituitary, CRBP II mRNA abundance were correlated to egg production rate, which increased from 12 wk to 32 wk, peaked at 32 wk relative to the other time points, and then decreased from 32 wk to 45 wk. In contrast, the expression of CRBP II mRNA in heart, jejunum, kidney, and liver was not different at any of the ages evaluated in this study. These data may help to understand the genetic basis of vitamin A metabolism, and suggest that CRBP II may be a candidate gene to affect egg production traits in chickens.

  19. EL español andino. II parte

    Directory of Open Access Journals (Sweden)

    Rubén Arboleda Toro

    2002-01-01

    Full Text Available En el número 13 de esta revista (nov. del 2000 se publicó una primera parte del estudio sobre el español andino. Presentamos ahora una segunda parte que comprende aspectos histórico-geográficos de Nariño y Putumayo andinos, región de Colombia donde se habla esa variedad, y una descripción general de su realidad lingüística. Esperamos que sean objeto de otra publicación la descripción de los rasgos dialectales del español andino, parte nuclear del trabajo, y la presentación de la metodología y el corpus. En esto nos encontramos trabajando. Incluimos no obstante un inventario de rasgos más amplio que el presentado en la primera parte. Pero por ahora se trata de eso, de un inventario ilustrativo, no del análisis en el que estamos empeñados, en el marco del contacto de lenguas, el cambio lingüístico y la relación entre la norma y las posibilidades del sistema. Para contextualizar esta segunda parte, incluimos, a manera de introducción, un resumen de la primera.

  20. Supraventricular tachycardia-Part II: History, presentation, mechanism, and treatment.

    Science.gov (United States)

    Lee, Ken W; Badhwar, Nitish; Scheinman, Melvin M

    2008-10-01

    Supraventricular tachycardias (SVTs) affect all age groups and are a source of significant morbidity. They are frequently encountered in otherwise healthy individuals without structural heart disease. Advances in the understanding of their mechanisms and anatomical locations have led to highly effective pharmacologic and nonpharmacologic treatment strategies. Recognition, identification, and differentiation of the various SVTs are of great importance in formulating an effective treatment strategy. Developments over the past four decades have made possible the accurate diagnosis of SVTs, and technological advances have led to ablative cures of most of these arrhythmias. This monograph provides an in-depth discussion of the history, presentation, mechanism, and treatment strategies of the most commonly encountered SVTs. The monograph is divided in two parts. Arrhythmias and related syndromes that are covered in detail in the first part include atrioventricular nodal reentrant tachycardia, Wolf-Parkinson-White syndrome, and atrioventricular reentrant tachycardia. The remaining SVTs are covered in the second part, which is presented here.

  1. Conformational behavior of insect pheromones and analogues. Part II

    Science.gov (United States)

    Koča, Jaroslav; Carlsen, Per H. J.

    1992-04-01

    The conformational potential energy surface paths of the sex pheromone, Ipsenol, to the Bark Beetle, Ips typographus, and of a series of analogues have been elucidated using the program DAISY. The following structures were calculated: 2-methyl-6-methylene-7-octen-4-ol (Ipsenol, ( II)), 2-methyl-6-methylene-2,7-octadiene-4-ol acetate ( III), 2-methyl-6-methylene-3,7-octadien-2-ol ( IV), 2-methyl-6-methylene-1,7-octadien-3-ol ( V), 5-(3-furanyl)-2-methyl-1-penten-3-ol ( VI) and 1-(3-furanyl)-4-methyl-3-penten-2-ol ( VII). As a measure of the conformational flexibility of the molecules the flexibility coefficients, f, were determined. The f values for the molecules were determined to be: II, 0.145; III, 0.144; IV, 1.240; V, 0.133; VI, 0.825; and VII, 0.451. The molecular mechanics method was used for energy calculations in conjunction with DAISY. Low-energy conformations (conformational channels) together with energy barriers for conformational changes are presented.

  2. Photochemistry on Pluto: part II HCN and nitrogen isotope fractionation

    Science.gov (United States)

    Mandt, Kathleen; Luspay-Kuti, Adrienn; Hamel, Mark; Jessup, Kandis-Lea; Hue, Vincent; Kammer, Josh; Filwett, Rachael

    2017-11-01

    We have converted our Titan one-dimensional photochemical model to simulate the photochemistry of Pluto's atmosphere and include condensation and aerosol trapping in the model. We find that condensation and aerosol trapping are important processes in producing the HCN altitude profile observed by the Atacama Large Millimeter Array (ALMA). The nitrogen isotope chemistry in Pluto's atmosphere does not appear to significantly fractionate the isotope ratio between N2 and HCN as occurs at Titan. However, our simulations only cover a brief period of time in a Pluto year, and thus only a brief portion of the solar forcing conditions that Pluto's atmosphere experiences. More work is needed to evaluate photochemical fractionation over a Pluto year. Condensation and aerosol trapping appear to have a major impact on the altitude profile of the isotope ratio in HCN. Since ALMA did not detect HC15N in Pluto's atmosphere, we conclude that condensation and aerosol trapping must be much more efficient for HC15N compared to HC14N. The large uncertainty in photochemical fractionation makes it difficult to use any potential current measurement of 14N/15N in N2 to determine the origin of Pluto's nitrogen. More work is needed to understand photochemical fractionation and to evaluate how condensation, sublimation and aerosol trapping will fractionate N2 and HCN.

  3. Collective action in labour conflicts under the Rome II regulation (part I)

    NARCIS (Netherlands)

    Dorssemont, F.; van Hoek, A.

    2011-01-01

    In this first part of our two-part study (the second part will be published in the next issue of the ELLJ), the authors discuss the background and the scope of application of Article 9 of the Rome II Regulation. This Article contains a special rule for the law applying to non-contractual obligations

  4. Solar Energy Education. Reader, Part II. Sun story. [Includes glossary

    Energy Technology Data Exchange (ETDEWEB)

    1981-05-01

    Magazine articles which focus on the subject of solar energy are presented. The booklet prepared is the second of a four part series of the Solar Energy Reader. Excerpts from the magazines include the history of solar energy, mythology and tales, and selected poetry on the sun. A glossary of energy related terms is included. (BCS)

  5. Nuclear cardiology, Part II: Scintigraphic evaluation of cardiac function.

    Science.gov (United States)

    Hambÿe, A S; Everaert, H; Maes, A; Mesotten, L; Vandevivere, J; Mortelmans, L; Franken, P R

    1998-06-01

    Different methods are currently available to assess cardiac function, especially left ventricular ejection fraction, using either planar or tomographic imaging, first-pass or equilibrium techniques, and blood-pool or myocardial perfusion agents. This is the second article of a four-part series on nuclear cardiology. In this article the authors review the most widely used radiopharmaceuticals and methodologies.

  6. Curriculum Guide for Hospitality Education. Part II. Exemplary Project.

    Science.gov (United States)

    Kalani, Henry

    This second of a two-part study designed to develop a hospitality education program model for Hawaii's community colleges is based on the primary data gathered in a survey of the hospitality industry characteristics, manpower requirements, and employment demands. (Survey data is reported in volume 1 of the study.) The introductory section of this…

  7. DIY Soundcard Based Temperature Logging System. Part II: Applications

    Science.gov (United States)

    Nunn, John

    2016-01-01

    This paper demonstrates some simple applications of how temperature logging systems may be used to monitor simple heat experiments, and how the data obtained can be analysed to get some additional insight into the physical processes. [For "DIY Soundcard Based Temperature Logging System. Part I: Design," see EJ1114124.

  8. Topics in Finance: Part II--Financial Analysis

    Science.gov (United States)

    Laux, Judy

    2010-01-01

    The second article in a series designed to supplement the introductory financial management course, this essay addresses financial statement analysis, including its impact on stock valuation, disclosure, and managerial behavior. [For "Topics in Finance Part I--Introduction and Stockholder Wealth Maximization," see EJ1060345.

  9. Vint Cerf on the World Wide Web. Part II.

    Science.gov (United States)

    Educom Review, 1996

    1996-01-01

    Presents the second part of an interview with Vinton Cerf on issues of information technology. Discusses reading with laptop computers; the "extinction" of books; technological experiments by publishers; copyrights, intellectual property, and ownership; cable companies; the impact of the Internet on education; and the future of the…

  10. Identifying Causes (Not Symptoms) of Writing Problems, Part II.

    Science.gov (United States)

    Strange, Dorothy Flanders; Kebbel, Gary W.

    1979-01-01

    Points out that writing errors of journalism students can result from faulty thought patterns involving thinking in sentence fragments, personifying objects, using bureaucratic abstractions, and condensing complex ideas; examines ways of dealing with bureaucratic coding and compressed sentences. (Conclusion of a two-part article.) (GT)

  11. Cogeneration from Poultry Industry Wastes -- Part II: Economic Analysis

    DEFF Research Database (Denmark)

    Bianchi, M.; Cherubini, F.; Pascale, A. D.

    2003-01-01

    of a Indirectly Fired Gas Turbine (Part I). Moreover a Steam Turbine Plant or a simplified system for the supply of the only technological steam are investigated and compared. Thermodynamic and economic analysis have been carried out for the examined configurations in order to outline the basic differences...

  12. Lagrangian intersection Floer theory anomaly and obstruction, part II

    CERN Document Server

    Fukaya, Kenji; Ohta, Hiroshi; Ono, Kaoru

    2009-01-01

    This is a two-volume series research monograph on the general Lagrangian Floer theory and on the accompanying homological algebra of filtered A_\\infty-algebras. This book provides the most important step towards a rigorous foundation of the Fukaya category in general context. In Volume I, general deformation theory of the Floer cohomology is developed in both algebraic and geometric contexts. An essentially self-contained homotopy theory of filtered A_\\infty algebras and A_\\infty bimodules and applications of their obstruction-deformation theory to the Lagrangian Floer theory are presented. Volume II contains detailed studies of two of the main points of the foundation of the theory: transversality and orientation. The study of transversality is based on the virtual fundamental chain techniques (the theory of Kuranishi structures and their multisections) and chain level intersection theories. A detailed analysis comparing the orientations of the moduli spaces and their fiber products is carried out. A self-co...

  13. Part I. Mechanisms of injury associated with extracorporeal shock wave lithotripsy; Part II. Exsolution of volatiles

    Science.gov (United States)

    Howard, Danny Dwayne

    Part I - Shock waves are focused in extracorporeal shock wave lithotripsy (ESWL) machines to strengths sufficient to fracture kidney stones. Substantial side effects-most of them acute-have resulted from this procedure, including injury to soft tissue. The focusing of shock waves through various layers of tissue is a complex process which stimulates many bio-mechano-chemical responses.This thesis presents results of an in vitro study of the initial mechanical stimulus. Planar nitrocellulose membranes of order 10 um thick were used as models of thin tissue structures. Two modes of failure were recorded: Failure due to cavitation collapsing on or near the membranes, and failure induced by altering the structure of shock waves. Tests were done in water at and around F2 to characterize the extent of cavitation damage, and was found to be confined within the focal region, 1.2 cm along the axis of focus.Scattering media were used to simulate the effects of acoustic nonuniformity of tissue and to alter the structure of focusing shock waves. 40 um diameter (average) hollow glass spheres were added to ethylene glycol, glycerine and castor oil to vary the properties of the scattering media. Multiple layer samples of various types of phantom tissue were tested in degassed castor oil to gauge the validity of the scattering media. The scattering media and tissue samples increased the rise time decreased strain rate in a similar fashion. Membranes were damaged by the decreased strain rate and accumulated effects of the altered structure: After about 20 or so shocks immersed in the scattering media and after about 100 shocks behind the tissue samples. The mode of failure was tearing with multiple tears in some cases from about .1 cm to about 3 cm depending of the number of shocks and membrane thickness.Part II - This work examines the exsolution of volatiles-carbon dioxide from water-in a cylindrical test cell under different pressure conditions. Water was supersaturated with

  14. The Mechanism of Graviton Exchange between Bodies, Part II

    DEFF Research Database (Denmark)

    Javadi, Hossein; Forouzbakhsh, Farshid

    2016-01-01

    Gravitational Law by space-time curvature. Quantum gravity is a part of quantum mechanics which is expected to combine these two theories, and it describes gravity force according to the principles of quantum mechanics which has not got the desired result, yet. In CPH theory, after reconsidering and analyzing...... the behavior of photon in the gravitational field, a new definition of graviton based on carrying the gravity force is given. By using this definition, graviton exchange mechanism between bodies/objects is described. As the purpose of quantum gravity is describing the force of gravity by using the principles...... given in which the relation between gravity (graviton) and electromagnetic (photon) have been described. In this part, the graviton exchange mechanism in the beneath of layer have studied and analyzed and it finally has been tried to generalize and extend the graviton exchange mechanism from between...

  15. GSTARS computer models and their applications, Part II: Applications

    Science.gov (United States)

    Simoes, F.J.M.; Yang, C.T.

    2008-01-01

    In part 1 of this two-paper series, a brief summary of the basic concepts and theories used in developing the Generalized Stream Tube model for Alluvial River Simulation (GSTARS) computer models was presented. Part 2 provides examples that illustrate some of the capabilities of the GSTARS models and how they can be applied to solve a wide range of river and reservoir sedimentation problems. Laboratory and field case studies are used and the examples show representative applications of the earlier and of the more recent versions of GSTARS. Some of the more recent capabilities implemented in GSTARS3, one of the latest versions of the series, are also discussed here with more detail. ?? 2008 International Research and Training Centre on Erosion and Sedimentation and the World Association for Sedimentation and Erosion Research.

  16. Design of multiphysics actuators using topology optimization - Part II

    DEFF Research Database (Denmark)

    Sigmund, Ole

    2001-01-01

    of the topology optimization method in this part include design descriptions for two-material structures, constitutive modelling of elements with mixtures of two materials, formulation of optimization problems with multiple constraints and multiple materials and a mesh-independency scheme for two......This is the second part of a two-paper description of the topology optimization method applied to the design of multiphysics actuators and electrothermomechanical systems in particular. The first paper is focussed on one-material structures, the second on two-material structures. The extensions......-material structures. The application in mind is the design of thermally and electro thermally driven micro actuators for use in MicroElectroMechanical Systems (MEMS). MEMS are microscopic mechanical systems coupled with electrical circuits. MEMS are fabricated using techniques known from the semi-conductor industry...

  17. Operation of industrial electrical substations. Part II: practical applications

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez Jimenez, Juan J; Zerquera Izquierdo, Mariano D; Beltran Leon, Jose S; Garcia Martinez, Juan M; Alvarez Urena, Maria V; Meza Diaz, Guillermo [Universidad de Guadalajara (Mexico)]. E-mails: cheosj@yahoo.com; mdzi@hotmail.com; beltran5601@yahoo.com.mx; jmargarmtz@yahoo.com; victory_alvarez@telmexmail.com; depmec@cucei.udg.mx

    2013-03-15

    The practical application of the methodology explained in Part 1 in a Cuban industry is the principal objective of this paper. The calculus of the economical operation of the principal transformers of the industrial plant is shown of the one very easy form, as well as the determination of the equations of the losses when the transformers operate under a given load diagram. It is calculated the state load which will be passed to the operation in parallel. [Spanish] El objetivo principal de este trabajo es la aplicacion practica de la metodologia, en una industria cubana, que se explico en la Parte 1. El calculo de la operacion economica de los principales transformadores de la planta industrial se muestra de una forma muy facil, asi como la determinacion de las ecuaciones de las perdidas cuando los transformadores operan bajo un diagrama de carga dado. Se calcula la carga de estado que se pasa a la operacion en paralelo.

  18. Prevention of Dealloying in Manganese Aluminium Bronze Propeller: Part II

    OpenAIRE

    Napachat Tareelap; Kaysinee Sriraksasin; Nakorn Srisukhumbowornchai; Swieng Thuanboon; Choochat Nitipanyawong

    2014-01-01

    Due to the failure of manganese aluminium bronze (MAB) propeller caused by dealloying corrosion as described in Part I [1], this work aims to study the prevention of dealloying corrosion using aluminium and zinc sacrificial anodes. The results indicated that both of the sacrificial anodes could prevent the propeller from dealloying. Moreover, the dealloying in seawater was less than that found in brackish water. It was possible that hydroxide ions, from cathodic reaction, reacted with calcium...

  19. Neutron detection with imaging plates Part II. Detector characteristics

    CERN Document Server

    Thoms, M

    1999-01-01

    On the basis of the physical processes described in Neutron detection with imaging plates - part I: image storage and readout [Nucl. Instr. and Meth. A 424 (1999) 26-33] detector characteristics, such as quantum efficiency, detective quantum efficiency, sensitivity to neutron- and gamma-radiation, readout time and dynamic range are predicted. It is estimated that quantum efficiencies and detective quantum efficiencies close to 100% can be reached making these kind of detectors interesting for a wide range of applications.

  20. The equivalence myth of quantum mechanics-part II

    Science.gov (United States)

    Muller, F. A.

    The author endeavours to show two things: first, that Schrödingers (and Eckarts) demonstration in March (September) 1926 of the equivalence of matrix mechanics, as created by Heisenberg, Born, Jordan and Dirac in 1925, and wave mechanics, as created by Schrödinger in 1926, is not foolproof; and second, that it could not have been foolproof, because at the time matrix mechanics and wave mechanics were neither mathematically nor empirically equivalent. That they were is the Equivalence Myth. In order to make the theories equivalent and to prove this, one has to leave the historical scene of 1926 and wait until 1932, when von Neumann finished his magisterial edifice. During the period 1926-1932 the original families of mathematical structures of matrix mechanics and of wave mechanics were stretched, parts were chopped off and novel structures were added. To Procrustean places we go, where we can demonstrate the mathematical, empirical and ontological equivalence of 'the final versions of' matrix mechanics and wave mechanics. The present paper claims to be a comprehensive analysis of one of the pivotal papers in the history of quantum mechanics: Schrödingers equivalence paper. Since the analysis is performed from the perspective of Suppes structural view ('semantic view') of physical theories, the present paper can be regarded not only as a morsel of the internal history of quantum mechanics, but also as a morsel of applied philosophy of science. The paper is self-contained and presupposes only basic knowledge of quantum mechanics. For reasons of length, the paper is published in two parts; Part I appeared in the previous issue of this journal. Section 1 contains, besides an introduction, also the papers five claims and a preview of the arguments supporting these claims; so Part I, Section 1 may serve as a summary of the paper for those readers who are not interested in the detailed arguments.

  1. Escapes in Hamiltonian systems with multiple exit channels: Part II

    OpenAIRE

    Zotos, Euaggelos E.

    2015-01-01

    We explore the escape dynamics in open Hamiltonian systems with multiple channels of escape continuing the work initiated in Part I. A thorough numerical investigation is conducted distinguishing between trapped (ordered and chaotic) and escaping orbits. The determination of the location of the basins of escape towards the different escape channels and their correlations with the corresponding escape periods of the orbits is undoubtedly an issue of paramount importance. We consider four diffe...

  2. Slag Behavior in Gasifiers. Part II: Constitutive Modeling of Slag

    Directory of Open Access Journals (Sweden)

    Mehrdad Massoudi

    2013-02-01

    Full Text Available The viscosity of slag and the thermal conductivity of ash deposits are among two of the most important constitutive parameters that need to be studied. The accurate formulation or representations of the (transport properties of coal present a special challenge of modeling efforts in computational fluid dynamics applications. Studies have indicated that slag viscosity must be within a certain range of temperatures for tapping and the membrane wall to be accessible, for example, between 1,300 °C and 1,500 °C, the viscosity is approximately 25 Pa·s. As the operating temperature decreases, the slag cools and solid crystals begin to form. Since slag behaves as a non-linear fluid, we discuss the constitutive modeling of slag and the important parameters that must be studied. We propose a new constitutive model, where the stress tensor not only has a yield stress part, but it also has a viscous part with a shear rate dependency of the viscosity, along with temperature and concentration dependency, while allowing for the possibility of the normal stress effects. In Part I, we reviewed, identify and discuss the key coal ash properties and the operating conditions impacting slag behavior.

  3. Parallel data access to regular nonorthogonal grid patterns. Part II

    Science.gov (United States)

    Creutzburg, Reiner

    2005-08-01

    The aim of this paper that is organized in three parts is to introduce the concept of parallel access of data in regular but not orthogonal grids. Although the orthogonal grid and the corresponding sampling methods are well-known for many years and well established in science and technology, there is a certain interest in 2- and 3-dimensional imaging to study trigonal and hexagonal grids. In the 2-dimensional case these grids are generated by tesellation of the plane using triangles and hexagons, respectively. They form very regular patterns and they have very nice properties according to the number of neighborhood pixels and distance values in electronic imaging. Moreover, it is known for a long time that the retina part of the human visual system can be modeled by a hexagonal packing structure of rods and cones. In this paper we study the connection and the influence of the necessary data structures, access patterns, and system architecture to model imaging algorithms with trigonal and hexagonal grids. In particular, we study the parallel access to straight lines and hexagonal "circles". We show a possible parallel memory architecture for the parallel conflict-free access to rows, straight lines and hexagonal "circles". The necessary fundamental notions are given in this part.

  4. Slag Behavior in Gasifiers. Part II: Constitutive Modeling of Slag

    Energy Technology Data Exchange (ETDEWEB)

    Massoudi, Mehrdad [National Energy Technology Laboratory; Wang, Ping

    2013-02-07

    The viscosity of slag and the thermal conductivity of ash deposits are among two of the most important constitutive parameters that need to be studied. The accurate formulation or representations of the (transport) properties of coal present a special challenge of modeling efforts in computational fluid dynamics applications. Studies have indicated that slag viscosity must be within a certain range of temperatures for tapping and the membrane wall to be accessible, for example, between 1,300 °C and 1,500 °C, the viscosity is approximately 25 Pa·s. As the operating temperature decreases, the slag cools and solid crystals begin to form. Since slag behaves as a non-linear fluid, we discuss the constitutive modeling of slag and the important parameters that must be studied. We propose a new constitutive model, where the stress tensor not only has a yield stress part, but it also has a viscous part with a shear rate dependency of the viscosity, along with temperature and concentration dependency, while allowing for the possibility of the normal stress effects. In Part I, we reviewed, identify and discuss the key coal ash properties and the operating conditions impacting slag behavior.

  5. Hermeneutics as an approach to science: Part II

    Science.gov (United States)

    Eger, Martin

    1993-12-01

    This paper continues the hermeneutic-phenomenological investigation of natural science, in which understanding plays a role comparable to creative construction (see ‘Hermeneutics as an Approach to Science: Part I’ in Science & Education 2(1)). The first issue treated is that of language: Is the language of science part of the equipment of the scientist, the subject, or part of the object itself — nature already linguistically encased? This issue, arising from the so-called argument of ‘the double hermeneutic’, relates the general question of the role of the subject in natural science to the role of interpretation. Examples of major interpretative developments in physics are discussed. The inquiry suggests that the role of interpretation and hermeneutics is tied to the educative or ‘study-mode’ of science; and that this mode can, apparently, be found at all levels and stages of science. The nature of this interpretive mode, and its relation to the creative mode, is then analyzed on the model of Gadamer's description of the interpretation of art.

  6. Fourier Transform Infrared Spectroscopy: Part II. Advantages of FT-IR.

    Science.gov (United States)

    Perkins, W. D.

    1987-01-01

    This is Part II in a series on Fourier transform infrared spectroscopy (FT-IR). Described are various advantages of FT-IR spectroscopy including energy advantages, wavenumber accuracy, constant resolution, polarization effects, and stepping at grating changes. (RH)

  7. The year 2012 in the European Heart Journal-Cardiovascular Imaging. Part II.

    Science.gov (United States)

    Plein, Sven; Knuuti, Juhani; Edvardsen, Thor; Saraste, Antti; Piérard, Luc A; Maurer, Gerald; Lancellotti, Patrizio

    2013-07-01

    The part II of the best of the European Heart Journal - Cardiovascular Imaging in 2012 specifically focuses on studies of valvular heart diseases, heart failure, cardiomyopathies, and congenital heart diseases.

  8. Premios nobel de quimica y filatelia. Parte II: Quimica analitica, quimica organica, productos naturales y bioquimica

    National Research Council Canada - National Science Library

    Martinez-Reina, Marlon; Amado-Gonzalez, Eliseo

    2013-01-01

    En Premios Nobel de Quimica y Filatelia, Parte II, se hace una revision de los sellos postales emitidos en diferentes paises para conmemorar los Premios Nobel en quimica analitica, quimica organica...

  9. 40 CFR Appendix II to Part 266 - Tier I Feed Rate Screening Limits for Total Chlorine

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Tier I Feed Rate Screening Limits for Total Chlorine II Appendix II to Part 266 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Screening Limits for Total Chlorine Terrain-adjusted effective stack height (m) Noncomplex Terrain Urban (g...

  10. Turbulence Measurements from Compliant Moorings. Part II: Motion Correction

    Energy Technology Data Exchange (ETDEWEB)

    Kilcher, Levi F. [National Renewable Energy Laboratory, Golden, Colorado; Thomson, Jim [Applied Physics Laboratory, University of Washington, Seattle, Washington; Harding, Samuel [Pacific Northwest National Laboratory, Richland, Washington; Nylund, Sven [Nortek AS, Rud, Norway

    2017-06-01

    Acoustic Doppler velocimeters (ADVs) are a valuable tool for making highprecision measurements of turbulence, and moorings are a convenient and ubiquitous platform for making many kinds of measurements in the ocean. However—because of concerns that mooring motion can contaminate turbulence measurements and acoustic Doppler profilers are relatively easy to deploy—ADVs are not frequently deployed from moorings. This work details a method for measuring turbulence using moored ADVs that corrects for mooring motion using measurements from inertial motion sensors. Three distinct mooring platforms were deployed in a tidal channel with inertial motion-sensor-equipped ADVs. In each case, the motion correction based on the inertial measurements dramatically reduced contamination from mooring motion. The spectra from these measurements have a shape that is consistent with other measurements in tidal channels, and have a f^(5/3) slope at high frequencies—consistent with Kolmogorov’s theory of isotropic turbulence. Motion correction also improves estimates of cross-spectra and Reynold’s stresses. Comparison of turbulence dissipation with flow speed and turbulence production indicates a bottom boundary layer production-dissipation balance during ebb and flood that is consistent with the strong tidal forcing at the site. These results indicate that inertial-motion-sensor-equipped ADVs are a valuable new tool for measuring turbulence from moorings.

  11. Prevention of Dealloying in Manganese Aluminium Bronze Propeller: Part II

    Directory of Open Access Journals (Sweden)

    Napachat Tareelap

    2014-03-01

    Full Text Available Due to the failure of manganese aluminium bronze (MAB propeller caused by dealloying corrosion as described in Part I [1], this work aims to study the prevention of dealloying corrosion using aluminium and zinc sacrificial anodes. The results indicated that both of the sacrificial anodes could prevent the propeller from dealloying. Moreover, the dealloying in seawater was less than that found in brackish water. It was possible that hydroxide ions, from cathodic reaction, reacted with calcium in seawater to form calcium carbonate film protecting the propeller from corrosion.

  12. Designing carbon markets, Part II: Carbon markets in space

    Energy Technology Data Exchange (ETDEWEB)

    Fankhauser, Samuel, E-mail: s.fankhauser@lse.ac.u [Grantham Research Institute and Centre for Climate Change Economics and Policy, London School of Economics, Houghton Street, London WC2A 2AE (United Kingdom); Hepburn, Cameron, E-mail: cameron.hepburn@economics.ox.ac.u [Grantham Research Institute, London School of Economics, and Smith School for Enterprise and the Environment, Oxford University, 75 George Street, Oxford OX1 2BQ (United Kingdom)

    2010-08-15

    This paper analyses the design of carbon markets in space (i.e., geographically). It is part of a twin set of papers that, starting from first principles, ask what an optimal global carbon market would look like by around 2030. Our focus is on firm-level cap-and-trade systems, although much of what we say would also apply to government-level trading and carbon offset schemes. We examine the 'first principles' of spatial design to maximise flexibility and to minimise costs, including key design issues in linking national and regional carbon markets together to create a global carbon market.

  13. The museum maze in oral pathology demystifed: part II.

    Science.gov (United States)

    Patil, Shankargouda; Rao, Roopa S; Ganavi, Bs

    2013-09-01

    Museum technology is perpetually changing due to current requirements and added inventions for our comfort and furbished display of specimens. Hence numerous methods of specimen preservation have been put on trial by diverse people in the medical feld as are the inventions. But only few have caught people's interest and are popularized today. This part provides unique insights into specialized custom-made techniques, evolution of recent advances like plastination and virtual museum that have popularized as visual delights. Plastination gives handy, perennial life-like acrylic specimens, whereas virtual museum takes museum feld to the electronic era making use of computers and virtual environment.

  14. Microgrids in Active Network Management-Part II

    DEFF Research Database (Denmark)

    Palizban, Omid; Kauhaniemi, Kimmo; Guerrero, Josep M.

    2014-01-01

    The development of distribution networks for participation in active network management (ANM) and smart grids is introduced using the microgrid concept. In recent years, this issue has been researched and implemented by many experts. The second part of this paper describes those developed......, following planned or unplanned transitions to island mode, microgrids may develop instability. For this reason, the paper addresses the principles behind island-detection methods, black-start operation, fault management, and protection systems, along with a comprehensive review of power quality. Finally...

  15. Vineland Adaptive Behavior Scales: II Profile of Young Children with Autism Spectrum Disorder

    Science.gov (United States)

    Yang, Sabrina; Paynter, Jessica M.; Gilmore, Linda

    2016-01-01

    Adaptive behaviour is a crucial area of assessment for individuals with Autism Spectrum Disorder (ASD). This study examined the adaptive behaviour profile of 77 young children with ASD using the Vineland-II, and analysed factors associated with adaptive functioning. Consistent with previous research with the original Vineland a distinct autism…

  16. Nanoparticles and the blood coagulation system. Part II: safety concerns

    Science.gov (United States)

    Ilinskaya, Anna N; Dobrovolskaia, Marina A

    2014-01-01

    Nanoparticle interactions with the blood coagulation system can be beneficial or adverse depending on the intended use of a nanomaterial. Nanoparticles can be engineered to be procoagulant or to carry coagulation-initiating factors to treat certain disorders. Likewise, they can be designed to be anticoagulant or to carry anticoagulant drugs to intervene in other pathological conditions in which coagulation is a concern. An overview of the coagulation system was given and a discussion of a desirable interface between this system and engineered nanomaterials was assessed in part I, which was published in the May 2013 issue of Nanomedicine. Unwanted pro- and anti-coagulant properties of nanoparticles represent significant concerns in the field of nanomedicine, and often hamper the development and transition into the clinic of many promising engineered nanocarriers. This part will focus on the undesirable effects of engineered nanomaterials on the blood coagulation system. We will discuss the relationship between the physicochemical properties of nanoparticles (e.g., size, charge and hydrophobicity) that determine their negative effects on the blood coagulation system in order to understand how manipulation of these properties can help to overcome unwanted side effects. PMID:23730696

  17. Biomedical informatics publications: a global perspective. Part II: Journals.

    Science.gov (United States)

    Maojo, V; Garcia-Remesal, M; Bielza, C; Crespo, J; Perez-Rey, D; Kulikowski, C

    2012-01-01

    Biomedical Informatics (BMI) is a broad discipline, having evolved from both Medical Informatics (MI) and Bioinformatics (BI). An analysis of publications in the fieldshould provide an indication about the geographic distribution of BMI research contributions and possible lessons for the future, both for research and professional practice. In part I of our analysis of biomedical informatics publications we presented results from BMI conferences. In this second part, we analyse BMI journals, which provide a broader perspective and comparison between data from conferences and journals that ought to confirm or suggest alternatives to the original distributional findings from the conferences. We manually collected data about authors and their geographical origin from various MI journals: the International Journal of Medical Informatics (IJMI), the Journal of Biomedical Informatics (JBI), Methods of In formation in Medicine (MIM) and The Journal of the American Medical Informatics Association (JAMIA). Focusing on first authors, we also compared these findings with data from the journal Bioinformatics. Our results confirm those obtained in our analysis of BMI conferences - that local and regional authors favor their corresponding MI journals just as they do their conferences. Consideration of other factors, such as the increasingly open source nature of data and software tools, is consistent with these findings. Our analysis suggests various indicators that could lead to further, deeper analyses, and could provide additional insights for future BMI research and professional activities.

  18. Histologic features of alopecias: part II: scarring alopecias.

    Science.gov (United States)

    Bernárdez, C; Molina-Ruiz, A M; Requena, L

    2015-05-01

    The diagnosis of disorders of the hair and scalp can generally be made on clinical grounds, but clinical signs are not always diagnostic and in some cases more invasive techniques, such as a biopsy, may be necessary. This 2-part article is a detailed review of the histologic features of the main types of alopecia based on the traditional classification of these disorders into 2 major groups: scarring and nonscarring alopecias. Scarring alopecias are disorders in which the hair follicle is replaced by fibrous scar tissue, a process that leads to permanent hair loss. In nonscarring alopecias, the follicles are preserved and hair growth can resume when the cause of the problem is eliminated. In the second part of this review, we describe the histologic features of the main forms of scarring alopecia. Since a close clinical-pathological correlation is essential for making a correct histopathologic diagnosis of alopecia, we also include a brief description of the clinical features of the principal forms of this disorder. Copyright © 2014 Elsevier España, S.L.U. and AEDV. All rights reserved.

  19. Iterative noise removal from temperature and density profiles in the TJ-II Thomson scattering

    Energy Technology Data Exchange (ETDEWEB)

    Farias, G., E-mail: gonzalo.farias@ucv.cl [Pontificia Universidad Católica de Valparaíso, Av. Brasil 2147, Valparaíso (Chile); Dormido-Canto, S., E-mail: sebas@dia.uned.es [Departamento de Informática y Automática, UNED, 28040 Madrid (Spain); Vega, J., E-mail: jesus.vega@ciemat.es [Asociación EURATOM/CIEMAT para Fusión, Avd. Complutense 22, 28040 Madrid (Spain); Santos, M., E-mail: msantos@ucm.es [Departamento de Arquitectura de Computadores y Automática, Universidad Complutense de Madrid, 28040 Madrid (Spain); Pastor, I., E-mail: ignacio.pastor@ciemat.es [Asociación EURATOM/CIEMAT para Fusión, Avd. Complutense 22, 28040 Madrid (Spain); Fingerhuth, S., E-mail: sebastian.fingerhuth@ucv.cl [Pontificia Universidad Católica de Valparaíso, Av. Brasil 2147, Valparaíso (Chile); Ascencio, J., E-mail: j_ascencio21@hotmail.com [Pontificia Universidad Católica de Valparaíso, Av. Brasil 2147, Valparaíso (Chile)

    2014-05-15

    TJ-II Thomson Scattering diagnostic provides temperature and density profiles of plasma. The CCD camera acquires images that are corrupted with some kind of noise called stray-light. This noise degrades both image contrast and measurement accuracy, which could produce unreliable profiles of the diagnostic. So far, several approaches have been applied in order to decrease the noise in the TJ-II Thomson scattering images. Since the presence of the noise is not global but located in some particular regions of the image, advanced processing techniques are needed. However such methods require of manual fine-tuning of parameters to reach a good performance. In this contribution, an iterative image processing approach is applied in order to reduce the stray light effects in the images of the TJ-II Thomson scattering diagnostic. The proposed solution describes how the noise can be iteratively reduced in the images when a key parameter is automatically adjusted during the iterative process.

  20. Surface grafted chitosan gels. Part II. Gel formation and characterization

    DEFF Research Database (Denmark)

    Liu, Chao; Thormann, Esben; Claesson, Per M.

    2014-01-01

    cross-linking the chitosan present in the polyelectrolyte multilayer, poly(acrylic acid) is partly removed by exposing the multilayer structure to a concentrated carbonate buffer solution at a high pH, leaving a surface-grafted cross-linked gel. Chemical cross-linking enhances the gel stability against......Responsive biomaterial hydrogels attract significant attention due to their biocompatibility and degradability. In order to make chitosan based gels, we first graft one layer of chitosan to silica, and then build a chitosan/poly(acrylic acid) multilayer using the layer-by-layer approach. After......-linking density. The amount of poly(acrylic acid) trapped inside the surface grafted films was found to decrease with decreasing cross-linking density, as confirmed in situ using TIRR, and ex situ by Fourier transform infrared (FTIR) measurements on dried films. The responsiveness of the chitosan-based gels...

  1. PERICARDITIS: ETIOLOGY, CLASSIFICATION, CLINIC, DIAGNOSTICS, TREATMENT. PART II

    Directory of Open Access Journals (Sweden)

    A.B. Sugak

    2009-01-01

    Full Text Available Pericarditis maybe caused by different agents: viruses, bacteria, tuberculosis, and it may be autoimmune. All these types of diseases have similar clinical signs, but differ by prevalence, prognosis and medical tactics. Due to achievements of radial methods of visualization, molecular biology, and immunology, we have an opportunity to provide early specific diagnostics and etiological treatment of inflammatory diseases of pericardium. The second part of lecture presents main principles of differential diagnostics of specific types of pericarditis, gives characteristics of several often accruing types of disease, and describes treatment and tactics of management of patients with pericarditis.Key words: children, pericarditis.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3:76-81

  2. Pulmonary Surfactants for Acute and Chronic Lung Diseases (Part II

    Directory of Open Access Journals (Sweden)

    O. A. Rozenberg

    2014-01-01

    Full Text Available Part 2 of the review considers the problem of surfactant therapy for acute respiratory distress syndrome (ARDS in adults and young and old children. It gives information on the results of surfactant therapy and prevention of ARDS in patients with severe concurrent trauma, inhalation injuries, complications due to complex expanded chest surgery, or severe pneumonias, including bilateral pneumonia in the presence of A/H1N1 influenza. There are data on the use of a surfactant in obstetric care and prevention of primary graft dysfunction during lung transplantation. The results of longterm use of surfactant therapy in Russia, suggesting that death rates from ARDS may be substantially reduced (to 20% are discussed. Examples of surfactant therapy for other noncritical lung diseases, such as permanent athelectasis, chronic obstructive pulmonary diseases, and asthma, as well tuberculosis, are also considered.

  3. FSW Numerical Simulation of Aluminium Plates by SYSWELD - Part II

    Directory of Open Access Journals (Sweden)

    Jančo Roland

    2016-11-01

    Full Text Available Friction Stir Welding (FSW is one of the most effective solid state joining processes and has numerous potential applications in many industries. The simulation process can provide the evolution of physicals quantities such as temperature, metallurgical phase proportions, stress and strain which can be easily measured during welding. The numerical modelling requires the modelling of the complex interaction between thermal, metallurgical and mechanical phenomena. The aim of this paper is to describe the thermal-fluid simulation of FSW using the finite element method. In the theoretical part of paper heating is provided by the material flow and contact condition between the tool and the welded material. Thermal-mechanical results from the numerical simulation using SYSWELD are also presented for aluminium alloy.

  4. On the problem of ethnophyletism: a historical study. Part II

    Directory of Open Access Journals (Sweden)

    Venediktov Vadim Yuriyevich

    2016-12-01

    Full Text Available The Holy and Great Council on Crete, 2016 has risen an important issue of Ethnophyletism. Russian, Georgian, Bulgarian, and Antiochian Orthodox Churches delegations were not present at the Great Council and were criticized for Ethnophyletism at the plenary session. The heresy of ethnophyletism was announced by the Council of Constantinople in 1872. Now we can see that it became essential nowadays. The article tells about the origin of this heresy and whether the Ethnophyletism may be decided to be the heresy. The second part of the paper deals with the events on the eve of the Pan-Orthodox Synod in 1872 (since the manifestation of the famous Abdülaziz Sultan's Firman 1870.

  5. Interacting quintessence from a variational approach Part II: derivative couplings

    CERN Document Server

    Boehmer, Christian G; Wright, Matthew

    2015-01-01

    We consider an original variational approach for building new models of quintessence interacting with dark or baryonic matter. The coupling is introduced at the Lagrangian level using a variational formulation for relativistic fluids, where the interacting term generally depends on both the dynamical degrees of freedom of the theory and their spacetime derivatives. After deriving the field equations from the action, we consider applications in the context of cosmology. Two simple models are studied using dynamical system techniques showing the interesting phenomenology arising in this framework. We find that these models contain dark energy dominated late time attractors with early time matter dominated epochs and also obtain a possible dynamical crossing of the phantom barrier. The formulation and results presented here complete and expand the analysis exposed in the first part of this work, where only algebraic couplings, without spacetime derivatives, were considered.

  6. Planar LTCC transformers for high voltage flyback converters: Part II.

    Energy Technology Data Exchange (ETDEWEB)

    Schofield, Daryl (NASCENTechnology, Inc., Watertown, SD); Schare, Joshua M., Ph.D.; Slama, George (NASCENTechnology, Inc., Watertown, SD); Abel, David (NASCENTechnology, Inc., Watertown, SD)

    2009-02-01

    This paper is a continuation of the work presented in SAND2007-2591 'Planar LTCC Transformers for High Voltage Flyback Converters'. The designs in that SAND report were all based on a ferrite tape/dielectric paste system originally developed by NASCENTechnoloy, Inc, who collaborated in the design and manufacturing of the planar LTCC flyback converters. The output/volume requirements were targeted to DoD application for hard target/mini fuzing at around 1500 V for reasonable primary peak currents. High voltages could be obtained but with considerable higher current. Work had begun on higher voltage systems and is where this report begins. Limits in material properties and processing capabilities show that the state-of-the-art has limited our practical output voltage from such a small part volume. In other words, the technology is currently limited within the allowable funding and interest.

  7. Sequencing of contents and learning objects - part II

    Directory of Open Access Journals (Sweden)

    Miguel Zapata Ros

    2006-01-01

    Full Text Available Esta es la segunda parte del artículo del mismo nombre publicado en el número anterior de RED. En él planteamos una visión de la selección y de la secuenciación de contenidos de enseñanza, en el contexto de la planificación curricular, desde la perspectiva de las corrientes del pensamiento constructivista. Señalamos la importancia de contar, en el campo de la formación apoyada en redes, con herramientas y criterios autónomos que guíen este proceso desde unas bases propias, externas y con preeminencia sobre las que derivan de la configuración de las herramientas tecnológicas, y desde la necesidad de contar con estándares de formato de intercambio de datos Si en general este planteamiento es importante adquiere especial relevancia en el contexto del e-learning de propósito general, tanto en el de formación como en el e-learning empresarial o en el universitario. Y por supuesto en el contexto de la formación reglada y de formación informal, o de la no reglada. También señalamos las necesidades que plantea la industria del e-learning en la actualidad en relación con el diseño instruccional de objetos de aprendizaje, necesidades que constituyen una prioridad y un desafío. En la primera parte desarrollamos la perspectiva constructivista y la conceptualización de servicios y herramientas tecnológicas como recursos educativos, así como una revisión de los conceptos vinculados con el e-learning, objetos de aprendizaje, OAR y reusabilidad. En esta parte abordaremos la fundamentación de las teorías que rigen los procedimientos de selección de contenidos, los presupuestos básicos y la descripción de las técnicas de secuenciación. En particular nos centraremos en tres de ellas: La técnica de análisis de contenidos, la técnica de análisis de la tarea y la Teoría de la Elaboración. Por último como conclusión, en la tercera parte, intentaremos abordar, no en su resolución sino solo en su propuesta como enunciado

  8. Eponyms in cardiothoracic radiology--part II: vascular.

    Science.gov (United States)

    Mohammed, Tan-Lucien H; Saettele, Megan R; Saettele, Timothy; Patel, Vikas; Kanne, Jeffrey P

    2014-01-01

    Eponyms serve the purpose of honoring individuals who have made important observations and discoveries. As with other fields of medicine, eponyms are frequently encountered in radiology, particularly in chest radiology. However, inappropriate use of an eponym may lead to potentially dangerous miscommunication. Moreover, an eponym may honor the incorrect person or a person who falls into disrepute. Despite their limitations, eponyms are still widespread in the medical literature. Furthermore, in some circumstances, more than one individual may have contributed to the description or discovery of a particular anatomical structure or disease, whereas in others, an eponym may have been incorrectly applied initially and propagated for years in the medical literature. Nevertheless, radiologic eponyms are a means of honoring those who have made lasting contributions to the field of radiology, and familiarity with these eponyms is critical for proper reporting and accurate communication. In addition, the acquisition of some historical knowledge about those whose names are associated with various structures or pathologic conditions conveys a sense of humanity in the science of medicine. In this second part of a multipart series, the authors discuss a number of chest radiology eponyms as they relate to the pulmonary vasculature, including relevant clinical and imaging features, as well biographic information of the respective eponym׳s namesake. Copyright © 2014 Elsevier Inc. All rights reserved.

  9. Stochastic dynamics of Arctic sea ice Part II: Multiplicative noise

    CERN Document Server

    Moon, Woosok

    2015-01-01

    We analyze the numerical solutions of a stochastic Arctic sea ice model with multiplicative noise over a wide range of external heat-fluxes, $\\Delta F_0$, which correspond to greenhouse gas forcing. When the noise is multiplicative, the noise-magnitude depends on the state-variable, and this will influence the statistical moments in a manner that differs from the additive case, which we analyzed in Part I of this study. The state variable describing the deterministic backbone of our model is the energy, $E(t)$, contained in the ice or the ocean and for a thorough comparison and contrast we choose the simplest form of multiplicative noise $\\sigma E(t) \\xi(t)$, where $\\sigma$ is the noise amplitude and $\\xi(t)$ is the noise process. The case of constant additive noise (CA) we write as $\\sigma\\overline{E_S}\\xi(t)$, in which $\\overline{E_S}$ is the seasonally averaged value of the periodic deterministic steady-state solution $E_S(t)$, or the deterministic seasonal cycle. We then treat the case of seasonally-varyi...

  10. Practice improvement, part II: update on patient communication technologies.

    Science.gov (United States)

    Roett, Michelle A; Coleman, Mary Thoesen

    2013-11-01

    Patient portals (ie, secure web-based services for patient health record access) and secure messaging to health care professionals are gaining popularity slowly. Advantages of web portals include timely communication and instruction, access to appointments and other services, and high patient satisfaction. Limitations include inappropriate use, security considerations, organizational costs, and exclusion of patients who are uncomfortable with or unable to use computers. Attention to the organization's strategic plan and office policies, patient and staff expectations, workflow and communication integration, training, marketing, and enrollment can facilitate optimal use of this technology. Other communication technologies that can enhance patient care include automated voice or text reminders and brief electronic communications. Social media provide another method of patient outreach, but privacy and access are concerns. Incorporating telehealthcare (health care provided via telephone or Internet), providing health coaching, and using interactive health communication applications can improve patient knowledge and clinical outcomes and provide social support. Written permission from the American Academy of Family Physicians is required for reproduction of this material in whole or in part in any form or medium.

  11. Recent applications of nuclear medicine in diagnostics: II part

    Directory of Open Access Journals (Sweden)

    Giorgio Treglia

    2013-04-01

    Full Text Available Introduction: Positron-emission tomography (PET and single photon emission computed tomography (SPECT are effective diagnostic imaging tools in several clinical settings. The aim of this article (the second of a 2-part series is to examine some of the more recent applications of nuclear medicine imaging techniques, particularly in the fields of neurology, cardiology, and infection/inflammation. Discussion: A review of the literature reveals that in the field of neurology nuclear medicine techniques are most widely used to investigate cognitive deficits and dementia (particularly those associated with Alzheimer disease, epilepsy, and movement disorders. In cardiology, SPECT and PET also play important roles in the work-up of patients with coronary artery disease, providing accurate information on the state of the myocardium (perfusion, metabolism, and innervation. White blood cell scintigraphy and FDG-PET are widely used to investigate many infectious/inflammatory processes. In each of these areas, the review discusses the use of recently developed radiopharmaceuticals, the growth of tomographic nuclear medicine techniques, and the ways in which these advances are improving molecular imaging of biologic processes at the cellular level.

  12. Advanced statistics: linear regression, part II: multiple linear regression.

    Science.gov (United States)

    Marill, Keith A

    2004-01-01

    The applications of simple linear regression in medical research are limited, because in most situations, there are multiple relevant predictor variables. Univariate statistical techniques such as simple linear regression use a single predictor variable, and they often may be mathematically correct but clinically misleading. Multiple linear regression is a mathematical technique used to model the relationship between multiple independent predictor variables and a single dependent outcome variable. It is used in medical research to model observational data, as well as in diagnostic and therapeutic studies in which the outcome is dependent on more than one factor. Although the technique generally is limited to data that can be expressed with a linear function, it benefits from a well-developed mathematical framework that yields unique solutions and exact confidence intervals for regression coefficients. Building on Part I of this series, this article acquaints the reader with some of the important concepts in multiple regression analysis. These include multicollinearity, interaction effects, and an expansion of the discussion of inference testing, leverage, and variable transformations to multivariate models. Examples from the first article in this series are expanded on using a primarily graphic, rather than mathematical, approach. The importance of the relationships among the predictor variables and the dependence of the multivariate model coefficients on the choice of these variables are stressed. Finally, concepts in regression model building are discussed.

  13. Institutional Approach in Economics and to Economics. Part II

    Directory of Open Access Journals (Sweden)

    Yefimov Vladimir, M.

    2015-12-01

    Full Text Available The paper attempts to justify an alternative to conventional methodology of economics, as well as make a corresponding revision of the history of this discipline. It explains why the discipline in its orthodox version, and for the most unorthodox directions, is cognitively sterile and socio-economico-politically very harmful. The paper can be seen as a manifesto which calls for a radical change in the discipline. As a manifesto, it probably could be called "Economics: from repentance and resurrection", that is, I suggest to economists to repent of the harm that this discipline has brought and on the basis of this reflection to revive it in the different methodological framework that is able to make economics socially useful. The second part of the paper, which is published in this issue, consists of two sections. In the first one (section number 4 economics is regarded as an institution and discusses its origin and evolution, as well as its current operation. On the basis of the analysis made in this section we can conclude that this institution has a very high degree of stability and because of that it cannot be reformed without an active external intervention. The fifth section of the paper is devoted to the link of the social role of economics with its methodology. It argues that the social function of economic science is the study of reality as it is, and underlines that economic education must be oriented in this direction.

  14. Cyclopentane combustion. Part II. Ignition delay measurements and mechanism validation

    KAUST Repository

    Rachidi, Mariam El

    2017-06-12

    This study reports cyclopentane ignition delay measurements over a wide range of conditions. The measurements were obtained using two shock tubes and a rapid compression machine, and were used to test a detailed low- and high-temperature mechanism of cyclopentane oxidation that was presented in part I of this study (Al Rashidi et al., 2017). The ignition delay times of cyclopentane/air mixtures were measured over the temperature range of 650–1350K at pressures of 20 and 40atm and equivalence ratios of 0.5, 1.0 and 2.0. The ignition delay times simulated using the detailed chemical kinetic model of cyclopentane oxidation show very good agreement with the experimental measurements, as well as with the cyclopentane ignition and flame speed data available in the literature. The agreement is significantly improved compared to previous models developed and investigated at higher temperatures. Reaction path and sensitivity analyses were performed to provide insights into the ignition-controlling chemistry at low, intermediate and high temperatures. The results obtained in this study confirm that cycloalkanes are less reactive than their non-cyclic counterparts. Moreover, cyclopentane, a high octane number and high octane sensitivity fuel, exhibits minimal low-temperature chemistry and is considerably less reactive than cyclohexane. This study presents the first experimental low-temperature ignition delay data of cyclopentane, a potential fuel-blending component of particular interest due to its desirable antiknock characteristics.

  15. Polymers Based on Renewable Raw Materials – Part II

    Directory of Open Access Journals (Sweden)

    Jovanović, S.

    2013-09-01

    Full Text Available A short review of biopolymers based on starch (starch derivatives, thermoplastic starch, lignin and hemicelluloses, chitin (chitosan and products obtained by degradation of starch and other polysaccharides and sugars (poly(lactic acid, poly(hydroxyalkanoates, as well as some of their basic properties and application area, are given in this part. The problem of environmental and economic feasibility of biopolymers based on renewable raw materials and their competitiveness with polymers based on fossil raw materials is discussed. Also pointed out are the problems that appear due to the increasing use of agricultural land for the production of raw materials for the chemical industry and energy, instead for the production of food for humans and animals. The optimistic assessments of experts considering the development perspectives of biopolymers based on renewable raw materials in the next ten years have also been pointed out.At the end of the paper, the success of a team of researchers gathered around the experts from the company Bayer is indicated. They were the first in the world to develop a catalyst by which they managed to effectively activate CO - and incorporate it into polyols, used for the synthesis of polyurethanes in semi-industrial scale. By applying this process, for the first time a pollutant will be used as a basic raw material for the synthesis of organic compounds, which will have significant consequences on the development of the chemical industry, and therefore the production of polymers.

  16. Medicine at the crossroads. Part II. Summary of completed project

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-05-01

    Medicine at the crossroads (a.k.a. The Future of Medicine) is an 8-part series of one-hour documentaries which examines the scientific and social forces that have shaped the practice of medicine around the world. The series was developed and produced over a five-year period and in eleven countries. Among the major issues examined in the series are the education of medical practitioners and the communication of medical issues. The series also considers the dilemmas of modern medicine, including the treatment of the elderly and the dying, the myth of the quick fix in the face of chronic and incurable diseases such as HIV, and the far-reaching implications of genetic treatments. Finally, the series examines the global progress made in medical research and application, as well as the questions remaining to be answered. These include not only scientific treatment, but accessibility and other critical topics affecting the overall success of medical advances. Medicine at the crossroads is a co-production of Thirteen/WNET and BBC-TV in association with Television Espafiola SA (RTVE) and the Australian Broadcasting Corporation. Stefan Moore of Thirteen/WNET and Martin Freeth of BBC-TV are series producers. George Page is executive in charge of medicine at the crossroads. A list of scholarly advisors and a program synopses is attached.

  17. Oral health in Brazil - Part II: Dental Specialty Centers (CEOs

    Directory of Open Access Journals (Sweden)

    Vinícius Pedrazzi

    2008-08-01

    Full Text Available The concepts of health promotion, self-care and community participation emerged during the 1970s and, since then, their application has grown rapidly in the developed world, showing evidence of effectiveness. In spite of this, a major part of the population in the developing countries still has no access to specialized dental care such as endodontic treatment, dental care for patients with special needs, minor oral surgery, periodontal treatment and oral diagnosis. This review focuses on a program of the Brazilian Federal Government named CEOs (Dental Specialty Centers, which is an attempt to solve the dental care deficit of a population that is suffering from oral diseases and whose oral health care needs have not been addressed by the regular programs offered by the SUS (Unified National Health System. Literature published from 2000 to the present day, using electronic searches by Medline, Scielo, Google and hand-searching was considered. The descriptors used were Brazil, Oral health, Health policy, Health programs, and Dental Specialty Centers. There are currently 640 CEOs in Brazil, distributed in 545 municipal districts, carrying out dental procedures with major complexity. Based on this data, it was possible to conclude that public actions on oral health must involve both preventive and curative procedures aiming to minimize the oral health distortions still prevailing in developing countries like Brazil.

  18. Collective action in labour conflicts under the Rome II regulation (part II)

    NARCIS (Netherlands)

    Dorssemont, F.; van Hoek, A.

    2011-01-01

    In this second part of our two-part contribution, we focus on the content of the choice of law rule of Article 9 and its relation to the other provisions of the Regulation. The application of the rule to some (in)famous cases - Tor Caledonia, Viking, Laval - demonstrates the difficulty in applying

  19. Why does Bangladesh remain so poor? Part II: eight answers.

    Science.gov (United States)

    Maloney, C

    1985-01-01

    Bangladeshis of varying background all over the country were asked why they think poverty persists to such an extent in Bangladesh. Their answers provide a new perspective on the situation. The initial response often blames outside and natural causes -- floods, droughts, lack of resources, low demand for the country's exports, or historic exploitation. It is true that Bangladesh has virtually no mineral resources except gas. Yet, the soil, water, and human labor add up to a huge potential. The Third Five Year Plan emphasizes use of the soil, irrigation, tanks, rivers, and human labor. These provide the only hope for reducing poverty a little during the next 5 years. Bangladeshis as well as foreign observers most commonly cite overpopulation as the cause of poverty. Population growth is a cause of present poverty in Bangladesh but is not the only cause of poverty. The Third Five Year Plan goal to reduce annual growth to 1.8% is ambitious, but even if it is achieved the population will double in a few decades. As it would most likely be impossible for Bangladesh to support such numbers and maintain political and economic stability, such growth will have to be prevented. Poverty in Bangladesh is party a result of the long history of low urbanization, weak institutions, spotty and inadequate physical infrastructure, and insufficient entrapreneurship. Other reasons cited as causes of persisting poverty include illiteracy, idleness, class exploitation, the selfishness of individuals, and a lack of trust among people. All of the efforts of the poor themselves, various agencies, and the government, as examined in the 1st part of this discussion, fail to indicate any reason to hope that poverty in Bangladesh can be dramatically reduced any time soon. The Third Five Year Plan foresees a possible reduction of the number of those in poverty by 10%. According to the Plan itself, those in or near poverty comprise 85% of the people. The conditions under which the people of some

  20. Neuromorphic meets neuromechanics, part II: the role of fusimotor drive

    Science.gov (United States)

    Jalaleddini, Kian; Minos Niu, Chuanxin; Chakravarthi Raja, Suraj; Sohn, Won Joon; Loeb, Gerald E.; Sanger, Terence D.; Valero-Cuevas, Francisco J.

    2017-04-01

    Objective. We studied the fundamentals of muscle afferentation by building a Neuro-mechano-morphic system actuating a cadaveric finger. This system is a faithful implementation of the stretch reflex circuitry. It allowed the systematic exploration of the effects of different fusimotor drives to the muscle spindle on the closed-loop stretch reflex response. Approach. As in Part I of this work, sensory neurons conveyed proprioceptive information from muscle spindles (with static and dynamic fusimotor drive) to populations of α-motor neurons (with recruitment and rate coding properties). The motor commands were transformed into tendon forces by a Hill-type muscle model (with activation-contraction dynamics) via brushless DC motors. Two independent afferented muscles emulated the forces of flexor digitorum profundus and the extensor indicis proprius muscles, forming an antagonist pair at the metacarpophalangeal joint of a cadaveric index finger. We measured the physical response to repetitions of bi-directional ramp-and-hold rotational perturbations for 81 combinations of static and dynamic fusimotor drives, across four ramp velocities, and three levels of constant cortical drive to the α-motor neuron pool. Main results. We found that this system produced responses compatible with the physiological literature. Fusimotor and cortical drives had nonlinear effects on the reflex forces. In particular, only cortical drive affected the sensitivity of reflex forces to static fusimotor drive. In contrast, both static fusimotor and cortical drives reduced the sensitivity to dynamic fusimotor drive. Interestingly, realistic signal-dependent motor noise emerged naturally in our system without having been explicitly modeled. Significance. We demonstrate that these fundamental features of spinal afferentation sufficed to produce muscle function. As such, our Neuro-mechano-morphic system is a viable platform to study the spinal mechanisms for healthy muscle function—and its

  1. Stress analysis in oral obturator prostheses, part II: photoelastic imaging.

    Science.gov (United States)

    Pesqueira, Aldiéris Alves; Goiato, Marcelo Coelho; da Silva, Emily Vivianne Freitas; Haddad, Marcela Filié; Moreno, Amália; Zahoui, Abbas; dos Santos, Daniela Micheline

    2014-06-01

    In part I of the study, two attachment systems [O-ring; bar-clip (BC)] were used, and the system with three individualized O-rings provided the lowest stress on the implants and the support tissues. Therefore, the aim of this study was to assess the stress distribution, through the photoelastic method, on implant-retained palatal obturator prostheses associated with different attachment systems: BOC--splinted implants with a bar connected to two centrally placed O-rings, and BOD--splinted implants with a BC connected to two distally placed O-rings (cantilever). One photoelastic model of the maxilla with oral-sinus-nasal communication with three parallel implants was fabricated. Afterward, two implant-retained palatal obturator prostheses with the two attachment systems described above were constructed. Each assembly was positioned in a circular polariscope and a 100-N axial load was applied in three different regions with implants by using a universal testing machine. The results were obtained through photograph record analysis of stress. The BOD system exhibited the highest stress concentration, followed by the BOC system. The O-ring, centrally placed on the bar, allows higher mobility of the prostheses and homogeneously distributes the stress to the region of the alveolar ridge and implants. It can be concluded that the use of implants with O-rings, isolated or connected with a bar, to rehabilitate maxillectomized patients allows higher prosthesis mobility and homogeneously distributes the stress to the alveolar ridge region, which may result in greater chewing stress distribution to implants and bone tissue. The clinical implication of the augmented bone support loss after maxillectomy is the increase of stress in the attachment systems and, consequently, a higher tendency for displacement of the prosthesis.

  2. Neuromorphic meets neuromechanics, part II: the role of fusimotor drive.

    Science.gov (United States)

    Jalaleddini, Kian; Minos Niu, Chuanxin; Chakravarthi Raja, Suraj; Joon Sohn, Won; Loeb, Gerald E; Sanger, Terence D; Valero-Cuevas, Francisco J

    2017-04-01

    We studied the fundamentals of muscle afferentation by building a Neuro-mechano-morphic system actuating a cadaveric finger. This system is a faithful implementation of the stretch reflex circuitry. It allowed the systematic exploration of the effects of different fusimotor drives to the muscle spindle on the closed-loop stretch reflex response. As in Part I of this work, sensory neurons conveyed proprioceptive information from muscle spindles (with static and dynamic fusimotor drive) to populations of α-motor neurons (with recruitment and rate coding properties). The motor commands were transformed into tendon forces by a Hill-type muscle model (with activation-contraction dynamics) via brushless DC motors. Two independent afferented muscles emulated the forces of flexor digitorum profundus and the extensor indicis proprius muscles, forming an antagonist pair at the metacarpophalangeal joint of a cadaveric index finger. We measured the physical response to repetitions of bi-directional ramp-and-hold rotational perturbations for 81 combinations of static and dynamic fusimotor drives, across four ramp velocities, and three levels of constant cortical drive to the α-motor neuron pool. We found that this system produced responses compatible with the physiological literature. Fusimotor and cortical drives had nonlinear effects on the reflex forces. In particular, only cortical drive affected the sensitivity of reflex forces to static fusimotor drive. In contrast, both static fusimotor and cortical drives reduced the sensitivity to dynamic fusimotor drive. Interestingly, realistic signal-dependent motor noise emerged naturally in our system without having been explicitly modeled. We demonstrate that these fundamental features of spinal afferentation sufficed to produce muscle function. As such, our Neuro-mechano-morphic system is a viable platform to study the spinal mechanisms for healthy muscle function-and its pathologies such as dystonia and spasticity. In

  3. Is extreme learning machine feasible? A theoretical assessment (part II).

    Science.gov (United States)

    Lin, Shaobo; Liu, Xia; Fang, Jian; Xu, Zongben

    2015-01-01

    An extreme learning machine (ELM) can be regarded as a two-stage feed-forward neural network (FNN) learning system that randomly assigns the connections with and within hidden neurons in the first stage and tunes the connections with output neurons in the second stage. Therefore, ELM training is essentially a linear learning problem, which significantly reduces the computational burden. Numerous applications show that such a computation burden reduction does not degrade the generalization capability. It has, however, been open that whether this is true in theory. The aim of this paper is to study the theoretical feasibility of ELM by analyzing the pros and cons of ELM. In the previous part of this topic, we pointed out that via appropriately selected activation functions, ELM does not degrade the generalization capability in the sense of expectation. In this paper, we launch the study in a different direction and show that the randomness of ELM also leads to certain negative consequences. On one hand, we find that the randomness causes an additional uncertainty problem of ELM, both in approximation and learning. On the other hand, we theoretically justify that there also exist activation functions such that the corresponding ELM degrades the generalization capability. In particular, we prove that the generalization capability of ELM with Gaussian kernel is essentially worse than that of FNN with Gaussian kernel. To facilitate the use of ELM, we also provide a remedy to such a degradation. We find that the well-developed coefficient regularization technique can essentially improve the generalization capability. The obtained results reveal the essential characteristic of ELM in a certain sense and give theoretical guidance concerning how to use ELM.

  4. An Occupation and Participation Approach to Reading Intervention (OPARI) Part II: Pilot Clinical Application

    Science.gov (United States)

    Grajo, Lenin C.; Candler, Catherine

    2016-01-01

    The Occupation and Participation Approach to Reading Intervention (OPARI) is an intervention approach for children with reading difficulties that emphasizes reading as an important occupation of children. Part I presented the theoretical basis of the OPARI. Part II describes a pilot clinical application of the OPARI. Guided by Schkade and…

  5. Literacy and Deaf Students in Taiwan: Issues, Practices and Directions for Future Research--Part II

    Science.gov (United States)

    Liu, Hsiu Tan; Andrews, Jean F.; Liu, Chun Jung

    2014-01-01

    In Part I, we underscore the issues surrounding young deaf and hard of hearing (DHH) learners of literacy in Taiwan who use sign to support their learning of Chinese literacy. We also described the linguistic features of Chinese writing and the visual codes used by DHH children. In Part II, we describe the reading and writing practices used with…

  6. Part II of the Landlord and Tenant Act 1954: Repeal of further reform? Part 1

    OpenAIRE

    Pawlowski, Mark; Brown, James

    2015-01-01

    It has been over 60 years since the enactment of Pt II of the Landlord and Tenant Act 1954. Since then, there have been two revisions of the legislation – one in 1969, which made limited amendments including the introduction of interim rents (see, the Law of Property Act 1969) and, more recently, under the Regulatory Reform (Business Tenancies) (England and Wales) Order 2003, which introduced more radical changes, particularly in relation to contracting out, notices and interim rents. To what...

  7. PGE Production in Southern Africa, Part II: Environmental Aspects

    Directory of Open Access Journals (Sweden)

    Benedikt Buchspies

    2017-11-01

    Full Text Available Platinum group elements (PGEs, 6E PGE = Pt + Pd + Rh + Ru + Ir + Au are used in numerous applications that seek to reduce environmental impacts of mobility and energy generation. Consequently, the future demand for PGEs is predicted to increase. Previous studies indicate that environmental impacts of PGE production change over time emphasizing the need of up-to-date data and assessments. In this context, an analysis of environmental aspects of PGE production is needed to support the environmental assessment of technologies using PGEs, to reveal environmental hotspots within the production chain and to identify optimization potential. Therefore, this paper assesses greenhouse gas (GHG emissions, cumulative fossil energy demand (CEDfossil, sulfur dioxide (SO2 emissions and water use of primary PGE production in Southern Africa, where most of today’s supply originates from. The analysis shows that in 2015, emissions amounted to 45 t CO2-eq. and 502 kg SO2 per kg 6E PGE in the case GHG and SO2 emissions, respectively. GHG emissions are dominated by emissions from electricity provision contributing more than 90% to the overall GHG emissions. The CEDfossil amounted to 0.60 TJ per kg 6E PGE. A detailed analysis of the CEDfossil reveals that electricity provision based on coal power consumes the most fossil energy carriers among all energy forms. Results show that the emissions are directly related to the electricity demand. Thus, the reduction in the electricity demand presents the major lever to reduce the consumption of fossil energy resources and the emission of GHGs and SO2. In 2015, the water withdrawal amounted to 0.272 million L per kg 6E PGE. Additionally, 0.402 million L of recycled water were used per kg 6E PGE. All assessed indicators except ore grades and production volumes reveal increasing trends in the period from 2010 to 2015. It can be concluded that difficult market conditions (see part I of this paper series and increasing

  8. PROBABILITY BASED CORROSION CONTROL FOR WASTE TANKS - PART II

    Energy Technology Data Exchange (ETDEWEB)

    Hoffman, E.; Edwards, T.

    2010-12-09

    As part of an ongoing study to evaluate the discontinuity in the corrosion controls at the SRS tank farm, a study was conducted this year to assess the minimum concentrations below 1 molar nitrate, see Figure 1. Current controls on the tank farm solution chemistry are in place to prevent the initiation and propagation of pitting and stress corrosion cracking in the primary steel waste tanks. The controls are based upon a series of experiments performed with simulated solutions on materials used for construction of the tanks, namely ASTM A537 carbon steel (A537). During FY09, an experimental program was undertaken to investigate the risk associated with reducing the minimum molar nitrite concentration required to confidently inhibit pitting in dilute solutions (i.e., less than 1 molar nitrate). The experimental results and conclusions herein provide a statistical basis to quantify the probability of pitting for the tank wall exposed to various solutions with dilute concentrations of nitrate and nitrite. Understanding the probability for pitting will allow the facility to make tank-specific risk-based decisions for chemistry control. Based on previous electrochemical testing, a statistical test matrix was developed to refine and solidify the application of the statistical mixture/amount model to corrosion of A537 steel. A mixture/amount model was identified based on statistical analysis of recent and historically collected electrochemical data. This model provides a more complex relationship between the nitrate and nitrite concentrations and the probability of pitting than is represented by the model underlying the current chemistry control program, and its use may provide a technical basis for the utilization of less nitrite to inhibit pitting at concentrations below 1 molar nitrate. FY09 results fit within the mixture/amount model, and further refine the nitrate regime in which the model is applicable. The combination of visual observations and cyclic

  9. Correction of Class II malocclusion and soft tissue profile in an adult patient

    Directory of Open Access Journals (Sweden)

    Aditi Gaur

    2016-01-01

    Full Text Available Treatment of Class II malocclusion in nongrowing individuals is a challenging situation for the clinician. Class II malocclusion with bialveolar protrusion often dictates premolar extractions with maximum anchorage. The present article describes the case of an adult female with skeletal Class II malocclusion, bimaxillary protrusion, increased overjet, deep bite, lip protrusion, everted lower lip, deep mentolabial sulcus, and lip incompetence. To correct the malocclusion, all four first premolars were extracted. Direct anchorage from miniscrews was used for retraction of the anterior segment. The mandibular buccal segment was protracted into the extraction space using Class II mechanics. Ideal Class I canine and molar relation were achieved in 24 months. There was a significant improvement in facial profile and smile esthetics of the patient.

  10. Correction of Class II malocclusion and soft tissue profile in an adult patient.

    Science.gov (United States)

    Gaur, Aditi; Maheshwari, Sandhya; Verma, Sanjeev Kumar

    2016-01-01

    Treatment of Class II malocclusion in nongrowing individuals is a challenging situation for the clinician. Class II malocclusion with bialveolar protrusion often dictates premolar extractions with maximum anchorage. The present article describes the case of an adult female with skeletal Class II malocclusion, bimaxillary protrusion, increased overjet, deep bite, lip protrusion, everted lower lip, deep mentolabial sulcus, and lip incompetence. To correct the malocclusion, all four first premolars were extracted. Direct anchorage from miniscrews was used for retraction of the anterior segment. The mandibular buccal segment was protracted into the extraction space using Class II mechanics. Ideal Class I canine and molar relation were achieved in 24 months. There was a significant improvement in facial profile and smile esthetics of the patient.

  11. PIO I-II tendencies. Part 2. Improving the pilot modeling

    Directory of Open Access Journals (Sweden)

    Ioan URSU

    2011-03-01

    Full Text Available The study is conceived in two parts and aims to get some contributions to the problem ofPIO aircraft susceptibility analysis. Part I, previously published in this journal, highlighted the mainsteps of deriving a complex model of human pilot. The current Part II of the paper considers a properprocedure of the human pilot mathematical model synthesis in order to analyze PIO II typesusceptibility of a VTOL-type aircraft, related to the presence of position and rate-limited actuator.The mathematical tools are those of semi global stability theory developed in recent works.

  12. New fuzzy EWMA control charts for monitoring phase II fuzzy profiles

    Directory of Open Access Journals (Sweden)

    Ghazale Moghadam

    2016-01-01

    Full Text Available In many quality control applications, the quality of a process or product is explained by the relationship between response variable and one or more explanatory variables, called a profile. In this paper, a new fuzzy EWMA control chart for phase II fuzzy profile monitoring is proposed. To this end, we extend EWMA control charts to its equivalent Fuzzy type and then implement fuzzy ranking methods to determine whether the process fuzzy profile is under or out of control. The proposed method is capable of identifying small changes in process under condition of process profile explaining parameters vagueness, roughness and uncertainty. Determining the source of changes, this method provides us with the possibility of recognizing the causes of process transition from stable mode, removing these causes and restoring the process stable mode.

  13. Factores de riesgo de preeclampsia: enfoque inmunoendocrino. Parte II Risk factors for preeclampsia: immunoendocrine approach. Part II

    Directory of Open Access Journals (Sweden)

    Jeddú Cruz Hernández

    2008-03-01

    Full Text Available Esta segunda parte de la revisión trata sobre los nuevos factores de riesgo de la preeclampsia, también conocidos como emergentes, entre los cuales se incluyen fenómenos biológicos de tipo endocrino, inmunológico y relacionados con la disfunción endotelial, como el aumento del estrés oxidativo, la disminución de las vitaminas antioxidantes y otros. Se augura que estos factores de riesgo de reciente descripción tendrán que ser tenidos muy en cuenta en un futuro no lejano, si se quiere predecir eficazmente la aparición de la preeclampsia para poder actuar así de forma precoz durante el desarrollo de la enfermedad, y evitar al máximo sus consecuencias obstétricas adversas, y en algunos casos, hasta para prevenir el surgimiento de esta enfermedad.This second part of the review deals with the new risk factors for preeclampsia, which are also known as emergent, among which the biological phenomena of endocrine and immunological type and related to endothelial dysfunction, such as the increase of oxidative stress, the reduction of antioxidant vitamins and others, are included. It is said that these recently described risk factors will have to be taken into account in a near future to efficiently predict the appearance of preeclampsia to act early during the development of the disease and to prevent as much as possible its adverse obstetric consequences and, in some cases, to avoid the appearance of this disease.

  14. Neurocognitive profiles in treatment-resistant bipolar I and bipolar II disorder depression.

    Science.gov (United States)

    Kessler, Ute; Schoeyen, Helle K; Andreassen, Ole A; Eide, Geir E; Hammar, Åsa; Malt, Ulrik F; Oedegaard, Ketil J; Morken, Gunnar; Sundet, Kjetil; Vaaler, Arne E

    2013-04-04

    The literature on the neuropsychological profiles in Bipolar disorder (BD) depression is sparse. The aims of the study were to assess the neurocognitive profiles in treatment-resistant, acutely admitted BD depression inpatients, to compare the neurocognitive functioning in patients with BD I and II, and to identify the demographic and clinical illness characteristics associated with cognitive functioning. Acutely admitted BD I (n = 19) and BD II (n = 32) inpatients who fulfilled the DSM-IV-TR criteria for a major depressive episode were tested with the MATRICS Consensus Cognitive Battery (MCCB), the Wechsler Abbreviated Scale of Intelligence, the National Adult Reading Test, and a battery of clinical measures. Neurocognitive impairments were evident in the BD I and BD II depression inpatients within all MCCB domains. The numerical scores on all MCCB-measures were lower in the BD I group than in the BD II group, with a significant difference on one of the measures, category fluency. 68.4% of the BD I patients had clinically significant impairment (>1.5 SD below normal mean) in two or more domains compared to 37.5% of the BD II patients (p = 0.045). A significant reduction in IQ from the premorbid to the current level was seen in BD I but not BD II patients. Higher age was associated with greater neurocognitive deficits compared to age-adjusted published norms. A high proportion of patients with therapy-resistant BD I or II depression exhibited global neurocognitive impairments with clinically significant severity. The cognitive impairments were more common in BD I compared to BD II patients, particularly processing speed. These findings suggest that clinicians should be aware of the severe neurocognitive dysfunction in treatment-resistant bipolar depression, particularly in BD I. NCT00664976.

  15. Low Profile Antenna Performance Study Part 2. Broadband Antenna Techniques Survey

    Science.gov (United States)

    1977-10-01

    shaped radiators, presented in the literature [141, [15], and depicted in Figs. 3b and c, resemble the biconical antenna and Alford’s tapered-horn...V Research and Development Technical Report .ECOM-4542 LOW PROFILE ANTENNA PERFORMANCE STUDY PART I1: BROADBAND ANTENNA TECHNIQUES SURVEY C. M...Small antenna , low-profile antenna , broadband matching, folded antennas , multi- element antennas , antenna loading. 90. ABSTRACT (Conlinu en revere, side

  16. 30 CFR Appendix II to Subpart D of... - Appendix II to Subpart D of Part 18

    Science.gov (United States)

    2010-07-01

    ... Part 18 LIST OF FIGURES Figure No. Title 1 Typical layout drawing of a machine. 2 Sample bill of material (to accompany layout drawing shown on figure 1) 3 Material to be included with the operating... the cable to guard against mechanical injury and wear. Splices in portable cables shall be made in a...

  17. Helping Children Cope with Fears and Stress. Part I: Discussion and Activities. Part II: Facilitator's Guide.

    Science.gov (United States)

    Robinson, Edward H.; And Others

    How fears, phobias, anxiety and stress develop in elementary school students and how these students can be assisted in coping with fears and stress are discussed in this book. Part 1, "Discussion and Activities," contains six sections. Section 1 presents an overview of fears, and stress in children. Section 2 presents 12 fear-specific activities…

  18. The Didactics of Biology. A Selected Bibliography for 1979. Part I [and] Part II.

    Science.gov (United States)

    Altmann, Antonin, Ed.; Lipertova, Pavla, Ed.

    Selected articles on various aspects of biology teaching published in 1979 have been annotated in this two-part bibliography. Entries from 18 journals representing 11 different countries are presented according to a topic area classification scheme listed in the table of contents. Countries represented include: Australia; Bulgaria; Czechoslovakia;…

  19. Didactics of Biology. Selective Bibliography, 1981. Part I [and] Part II. Information Bulletin.

    Science.gov (United States)

    Altmann, Antonin, Ed.; Lipertova, Pavla, Ed.

    Selected articles on various aspects of biology teaching published in 1980 have been annotated in this two-part bibliography. Entries from 19 journals representing 11 different countries are presented according to a topic area classification scheme listed in the table of contents. Countries represented include: Australia; Bulgaria; Czechoslovakia;…

  20. The Didactics of Biology. Selected Bibliography for 1980. Part I [and] Part II.

    Science.gov (United States)

    Altmann, Antonin, Ed.; Lipertova, Pavla, Ed.

    Selected articles on various aspects of biology teaching published in 1979 have been annotated in this two-part bibliography. Entries from 19 journals representing 11 different countres are presented according to a topic area classification scheme listed in the table of contents. Countries represented include: Australia; Bulgaria; Czechoslovakia;…

  1. Part II

    DEFF Research Database (Denmark)

    Guo, Song; Vollesen, Anne Luise Haulund; Hansen, Young Bae Lee

    2017-01-01

    the start of the infusion. A control group of six healthy volunteers received intravenous saline. Results PACAP38 infusion caused significant changes in plasma concentrations of VIP ( p = 0.026), prolactin ( p = 0.011), S100B ( p thyroid-stimulating hormone (TSH; p = 0.015), but not CGRP ( p...... with and without the MEF2D-associated gene variant ( p > 0.05). Conclusion PACAP38 infusion elevated the plasma levels of VIP, prolactin, S100B and TSH, but not CGRP and TNFα. Development of delayed migraine-like attacks or the presence of the MEF2D gene variant was not associated with pre-ictal changes in plasma...... levels of neuropeptides, TNFα and pituitary hormones....

  2. Facial profile changes in early Class II correction with cervical headgear.

    Science.gov (United States)

    Kirjavainen, Mirja; Hurmerinta, Kirsti; Kirjavainen, Turkka

    2007-11-01

    To characterize the effects of early cervical headgear treatment on the facial profile of children in Class II division 1 malocclusion. Forty children aged 9.1 (7.2-11.5) years with Class II division 1 malocclusion were treated using a cervical headgear appliance. The headgear consisted of a long outer bow bent upward 15 degrees and a large expanded inner bow. Lateral cephalograms were taken before and after treatment, and the facial profile was estimated from the cephalograms. The results were compared to an age- and sex-matched normal cohort of 644 Finnish children. Class I molar relationship was achieved in all treated children. The treatment time was 1.6 (0.3-3.1) years on average. Compared to the controls, the treatment restricted the forward growth of maxillary A-point, and the SNA angle decreased 1.4 degrees +/- 1.2 degrees per year (P headgear treatment in Class II correction is associated with a decreased facial convexity caused by the restriction of forward growth of the maxillary A-point, while the rest of the facial profile, including the mandible, continue to grow forward at a normal rate.

  3. INFORMATION SHARING IN OLIGOPOLY: OVERVIEW AND EVALUATION PART II. PRIVATE RISKS AND OLIGOPOLY MODELS

    OpenAIRE

    Sakai, Yasuhiro

    1991-01-01

    Part I of this paper has first discussed the dual relationship between the Cournot and Bertrand duopoly models in the absence of uncertainty, and has then proceeded to focus on various types of duopoly models facing a common risk of demand or cost. It has been shown that the welfare consequences of an information transmission agreement between the firms are clasified under four headings: own and cross variation effects, and own and cross efficiency effects. Part II of the paper will now turn ...

  4. Ocean Thermal Energy Conversion (OTEC) test facilities study program. Final report. Volume II. Part A

    Energy Technology Data Exchange (ETDEWEB)

    1977-01-17

    Results are presented of an 8-month study to develop alternative non-site-specific OTEC facilities/platform requirements for an integrated OTEC Test Program which may include land and floating test facilities. The document, Volume II - Appendixes is bound in three parts (A, B, and C) which together comprise a compendium of the most significant detailed data developed during the study. Part A contains definitions, baseline revisions, test plans, and energy utilization sections.

  5. A History of Instructional Design and Technology: Part II: A History of Instructional Design.

    Science.gov (United States)

    Reiser, Robert A.

    2001-01-01

    This second of a two-part article focuses on the history of instructional design in the United States. Starting with its origins during World War II, major events in the development of instructional design are described. Factors affecting the field over the last two decades, including increasing interest in cognitive psychology, microcomputers,…

  6. Title II, Part A: Don't Scrap It, Don't Dilute It, Fix It

    Science.gov (United States)

    Coggshall, Jane G.

    2015-01-01

    The Issue: Washington is taking a close look at Title II, Part A (Title IIA) of the Elementary and Secondary Education Act (ESEA) as Congress debates reauthorization. The program sends roughly $2.5 billion a year to all states and nearly all districts to "(1) increase student academic achievement through strategies such as improving teacher…

  7. 7 squadron in World War II (Part 2: 1943-1945) | Robinson | Scientia ...

    African Journals Online (AJOL)

    Scientia Militaria: South African Journal of Military Studies. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 5, No 3 (1975) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register. 7 squadron in World War II (Part ...

  8. Managing the care of health and the cure of disease--Part II: Integration.

    Science.gov (United States)

    Glouberman, S; Mintzberg, H

    2001-01-01

    The development of appropriate levels of integration in the system of health care and disease cure will require stronger collective cultures and enhanced communication among the key actors. Part II of this paper uses this line of argument to reframe four major issues in this system: coordination of acute cure and of community care, and collaboration in institutions and in the system at large.

  9. Student Performance on the NBME Part II Subtest and Subject Examination in Obstetrics-Gynecology.

    Science.gov (United States)

    Metheny, William P.; Holzman, Gerald B.

    1988-01-01

    Comparison of the scores of 342 third-year medical students on the National Board of Medical Examiners subject examination and the Part II subtest on obstetrics-gynecology found significantly better performance on the former, suggesting a need to interpret the scores differently. (Author/MSE)

  10. Predicting performance on the Medical Council of Canada Qualifying Exam Part II.

    Science.gov (United States)

    Woloschuk, Wayne; McLaughlin, Kevin; Wright, Bruce

    2013-01-01

    Being able to predict which residents will likely be unsuccessful on high-stakes exams would allow residency programs to provide early intervention. To determine whether measures of clinical performance in clerkship (in-training evaluation reports) and first year of residency (program director ratings) predict pass-fail performance on the Medical Council of Canada Qualifying Exam Part II (MCCQE Part II). Residency program directors assessed the performance of our medical school graduates (Classes 2004-2007) at the end of the 1st postgraduate year. We subsequently collected clerkship in-training evaluation reports for these graduates. Using a neutral third party and unique codes, an anonymous dataset containing clerkship, residency, and MCCQE Part II performance scores was created for our use. Data were analyzed using descriptive statistics, correlations, receiver operating characteristics, and the Youdin index. Regression was also performed to further study the relationship among the variables. Complete data were available for 78.6% of the graduates. Of these participants, 94% passed the licensing exam on their first attempt. Receiver operating characteristics revealed that the area under the curve for clerkship in-training evaluation reports was 0.67 (ptraining evaluation reports and residency program director assessments were 0.30 and 0.23, respectively. Although clerkship in-training evaluation reports and residency program director ratings are significant predictors of pass-fail performance on the MCCQE Part II, the effectiveness of each one to predict pass-fail performance was relatively small. Reasons for these findings are discussed.

  11. Validity and Reliability of Health Promoting Lifestyle Profile II in the Iranian Elderly.

    Science.gov (United States)

    Tanjani, Parisa Taheri; Azadbakht, Mojtaba; Garmaroudi, Gholamreza; Sahaf, Robab; Fekrizadeh, Zohreh

    2016-01-01

    With increasing age, the prevalence of chronic diseases increases. Since health-promoting behaviors (HPB) are considered a basic way of preventing diseases, especially chronic diseases, it is important to assess HPB. This study examines the validity and reliability of the Health Promoting Lifestyle Profile II (HPLP-II). This is a cross-sectional study which is conducted on 502 elderly individuals aged 60 and over in Tehran, Iran. In order to determine the validity, content and construct validity were used. The content validity index (CVI) was used to assess the content validity and to assess construct validity, confirmatory factor analysis (CFA), and item-total correlations were employed. For reliability, test-retest analysis was used, and the internal consistency of the HPLP-II was confirmed by Cronbach's alpha. For data analysis, SPSS-18 and Amos-7 software was used. The mean age of the subjects was 66.3 ± 5.3 years. The CVI for the revised HPLP-II and all its subscales was higher than 0.82. The CFA confirmed a six-factor model aligned with the original HPLP-II. Pearson correlation coefficients between the revised HPLP-II and their items were in range of 0.27-0.65. Cronbach's alpha of the revised HPLP-II was obtained as 0.78 and for their subscales were in the range of 0.67-0.84. Intraclass correlation coefficient was obtained 0.79 (95% confidence interval: 0.59-0.86, P assessing HPBs of the Iranian elderly.

  12. A primer for clinical researchers in the emergency department: Part II: research science and conduct.

    Science.gov (United States)

    Babl, Franz E; Davidson, Andrew

    2010-10-01

    Research is an important part of emergency medicine and provides the scientific underpinning for optimal patient care. Although increasing numbers of emergency physicians participate in research activities, formal research training is currently neither part of emergency physician training in Australia nor easily available for clinicians interested in clinical research. In a two-part series, which is targeted at part-time clinical researchers in the ED, we set out and explain the key elements for conducting high-quality and ethical research. Part I addressed ethical and regulatory aspects. In Part II, we describe important elements of research science, and practical elements of research conduct and administration, which form the basis for high-quality research. © 2010 The Authors. Emergency Medicine Australasia © 2010 Australasian College for Emergency Medicine and Australasian Society for Emergency Medicine.

  13. In vitro performance of Class I and II composite restorations: a literature review on nondestructive laboratory trials--part II.

    Science.gov (United States)

    Dietschi, D; Argente, A; Krejci, I; Mandikos, M

    2013-01-01

    A literature review was conducted on adhesive Class I and II restorations and nondestructive in vitro tests using the PubMed/Medline database for the 1995-2010 period. The first part of this review has presented and critically appraised selected literature dealing with the quality and in vitro behavior of adhesive Class II restorations using photoelasticity, finite element analysis, and microleakage study protocols. This second part reviews additional parameters, which are deformation and fracture resistance to cyclic loading, shrinkage stress and tooth deformation following restoration placement, bond strength (microtensile, tensile, and shear tests), and marginal and internal adaptation. In addition, a "relevance score" has been proposed that aims to classify the different study protocols according, firstly, to the resulting quality, quantity, and consistency of the evidence and then, secondly, to their potential clinical relevance, as estimated by their ability to simulate oral and biomechanical strains. The highest clinical relevance was attributed to marginal and internal adaptation studies, following cyclic loading in a moist environement. However, a combination of in vitro protocols will have an even greater predictive potential and has to be considered as a crucial preclinical research approach with which to investigate the numerous restorative configurations that cannot be efficiently and rapidly tested in vivo.

  14. SALINITY, HYDROSTATIC PRESSURE, SIGMA-THETA, FLUORESCENCE and other profile data collected in the Gulf of Guinea, Mediterranean Sea - Western Basin and others on NOAA Ship ALBATROSS IV, ENDEAVOR and other platforms cruises AL9306, AL9403II and others as part of the GB project from 1993-05-22 to 1997-05-17 (NODC Accession 0107210)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0107210 includes profile, biological and physical data collected aboard NOAA Ship ALBATROSS IV, ENDEAVOR, OCEANUS and SEWARD JOHNSON during cruises...

  15. Low Profile Antenna Performance Study. Part 1. Efficiency and Bandwidth Characteristics

    Science.gov (United States)

    1977-06-01

    antenna , is being distributed to users in the field. The UE-254, also a biconical antenna , has been type-classified and will even- tually replace the RC...Research and Development Technical Report 00 ECOM-4502 LOW-PROFILE ANTENNA PERFORMANCE STUDY MCCC C. M. DeSantis Communications/Automatic Data...ACCESIC N NO. J HCIPFtNT- CATA0OG NUMBER rpmrow a’ "EIon COVERED Low Prcfile Antenna Performance Study *’FINAL Sep~ 075- Part I: Efficiency

  16. Rail and multimodal freight: a problem-oriented survey (part II-2

    Directory of Open Access Journals (Sweden)

    Marin MARINOV

    2009-01-01

    Full Text Available This paper includes the Part II-2 of the series of problem-oriented surveys on rail and multimodal freight transportation services, which aim is to reveal the current situation in this sector and raises looming questions for discussion. The particular objective of Part II-2 is to discuss recently published works and documents dedicated to Multi-actor chain management and control, Mode choice and pricing strategies, Intermodal transportation policy and planning as well as Miscellaneous. It should be noted that this paper is a problem oriented survey and does not explicitly focus on the available scientific instrumental that has been applied in dealing with rail and multimodal freight. However, throughout the description methods and concepts are addressed, where it is of interest.

  17. Bloqueio do nervo supraescapular: procedimento importante na prática clínica. Parte II Suprascapular nerve block: important procedure in clinical practice. Part II

    Directory of Open Access Journals (Sweden)

    Marcos Rassi Fernandes

    2012-08-01

    Full Text Available O bloqueio do nervo supraescapular é um método de tratamento reprodutível, confiável e extremamente efetivo no controle da dor no ombro. Esse método tem sido amplamente utilizado por profissionais na prática clínica, como reumatologistas, ortopedistas, neurologistas e especialistas em dor, na terapêutica de enfermidades crônicas, como lesão irreparável do manguito rotador, artrite reumatoide, sequelas de AVC e capsulite adesiva, o que justifica a presente revisão (Parte II. O objetivo deste estudo foi descrever as técnicas do procedimento e suas complicações descritas na literatura, já que a primeira parte reportou as indicações clínicas, drogas e volumes utilizados em aplicação única ou múltipla. Apresentamse, detalhadamente, os acessos para a realização do procedimento tanto direto como indireto, anterior e posterior, lateral e medial, e superior e inferior. Diversas são as opções para se realizar o bloqueio do nervo supraescapular. Apesar de raras, as complicações podem ocorrer. Quando bem indicado, este método deve ser considerado.The suprascapular nerve block is a reproducible, reliable, and extremely effective treatment method in shoulder pain control. This method has been widely used by professionals in clinical practice such as rheumatologists, orthopedists, neurologists, and pain specialists in the treatment of chronic diseases such as irreparable rotator cuff injury, rheumatoid arthritis, stroke sequelae, and adhesive capsulitis, which justifies the present review (Part II. The objective of this study was to describe the techniques and complications of the procedure described in the literature, as the first part reported the clinical indications, drugs, and volumes used in single or multiple procedures. We present in details the accesses used in the procedure: direct and indirect, anterior and posterior, lateral and medial, upper and lower. There are several options to perform suprascapular nerve block

  18. Stabilized finite elements for Bingham and Herschel-Bulkley confined flows Part II: Numerical simulations

    OpenAIRE

    Moreno, E.; Cervera, M.

    2016-01-01

    The objective of this work is to model computationally Bingham and Herschel-Bulkley viscoplastic fluids using stabilized mixed velocity/pressure finite elements. Numerical solutions for these viscoplastic flows are presented and assessed. The regularized viscoplastic models due to Papanastasiou is used. In the discrete model, the Orthogonal Subgrid scale (OSS) method is used. In this part II , numerical solutions for two problems of Bingham and Herschel-Bulkley confined flows are presente...

  19. DEVELOPMENT OF AN ARMY STATIONARY AXLE TEST STAND FOR LUBRICANT EFFICIENCY EVALUATION-PART II

    Science.gov (United States)

    2017-01-13

    EFFICIENCY TEST STAND – PART II INTERIM REPORT TFLRF No. 484 by Adam C. Brandt Edwin A. Frame U.S. Army TARDEC Fuels and Lubricants...efficiency test stand to allow for laboratory based investigation of Fuel Efficient Gear Oils (FEGO) and their impact on vehicle efficiency. Development...differentiation of efficiency between tested lubricants was achieved in the low speed/lower load operating conditions of the FTM cycle , while efficiency

  20. Societal Planning: Identifying a New Role for the Transport Planner-Part II: Planning Guidelines

    DEFF Research Database (Denmark)

    Khisty, C. Jotin; Leleur, Steen

    1997-01-01

    The paper seeks to formulate planning guidelines based on Habermas's theory of communicative action. Specifically, this has led to the formulation of a set of four planning validity claims concerned to four types of planning guidelines concerning adequacy, dependency, suitability and adaptability......-a-vis the planning validity claims. Among other things the contingency of this process is outlined. It is concluded (part I & II) that transport planners can conveniently utilize the guidelines in their professional practice, tailored to their particular settings....

  1. Partial covering of a circle by equal circles. Part II: The case of 5 circles

    Directory of Open Access Journals (Sweden)

    Zsolt Gáspár

    2014-05-01

    Full Text Available How must n equal circles of given radius r be placed so that they cover as great a part of the area of the unit circle as possible? In this Part II of a two-part paper, a conjectured solution of this problem for n = 5 is given for r varying from the maximum packing radius to the minimum covering radius. Results are obtained by applying a mechanical model described in Part I. A generalized tensegrity structure is associated with a maximum area configuration of the 5 circles, and by using catastrophe theory, it is pointed out that the ''equilibrium paths'' have bifurcations, that is, at certain values of r, the type of the tensegrity structure and so the type of the circle configuration changes.

  2. A thermoelectric power generating heat exchanger: Part II – Numerical modeling and optimization

    DEFF Research Database (Denmark)

    Sarhadi, Ali; Bjørk, Rasmus; Lindeburg, N.

    2016-01-01

    In Part I of this study, the performance of an experimental integrated thermoelectric generator (TEG)-heat exchanger was presented. In the current study, Part II, the obtained experimental results are compared with those predicted by a finite element (FE) model. In the simulation of the integrated...... TEG-heat exchanger, the thermal contact resistance between the TEG and the heat exchanger is modeled assuming either an ideal thermal contact or using a combined Cooper–Mikic–Yovanovich (CMY) and parallel plate gap formulation, which takes into account the contact pressure, roughness and hardness...

  3. Ocean Thermal Energy Conversion (OTEC) test facilities study program. Final report. Volume II. Part C

    Energy Technology Data Exchange (ETDEWEB)

    None

    1977-01-17

    Results are presented of an 8-month study to develop alternative non-site-specific OTEC facilities/platform requirements for an integrated OTEC Test Program which may include land and floating test facilities. Volume II--Appendixes is bound in three parts (A, B, and C) which together comprise a compendium of the most significant detailed data developed during the study. Part C describes test facility support, data acquisition and control system design, cost data, energy self-sufficiency, and test facility applications.

  4. The year 2013 in the European Heart Journal--Cardiovascular Imaging: Part II.

    Science.gov (United States)

    Plein, Sven; Edvardsen, Thor; Pierard, Luc A; Saraste, Antti; Knuuti, Juhani; Maurer, Gerald; Lancellotti, Patrizio

    2014-08-01

    The new multi-modality cardiovascular imaging journal, European Heart Journal - Cardiovascular Imaging, was created in 2012. Here we summarize the most important studies from the journal's second year in two articles. Part I of the review has summarized studies in myocardial function, myocardial ischaemia, and emerging techniques in cardiovascular imaging. Part II is focussed on valvular heart diseases, heart failure, cardiomyopathies, and congenital heart diseases. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2014. For permissions please email: journals.permissions@oup.com.

  5. 40 CFR Appendix III to Part 266 - Tier II Emission Rate Screening Limits for Free Chlorine and Hydrogen Chloride

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Tier II Emission Rate Screening Limits for Free Chlorine and Hydrogen Chloride III Appendix III to Part 266 Protection of Environment... to Part 266—Tier II Emission Rate Screening Limits for Free Chlorine and Hydrogen Chloride Terrain...

  6. Alchemical poetry in medieval and early modern Europe: a preliminary survey and synthesis. Part II - Synthesis.

    Science.gov (United States)

    Kahn, Didier

    2011-03-01

    This article provides a preliminary description of medieval and early modern alchemical poetry composed in Latin and in the principal vernacular languages of western Europe. It aims to distinguish the various genres in which this poetry flourished, and to identify the most representative aspects of each cultural epoch by considering the medieval and early modern periods in turn. Such a distinction (always somewhat artificial) between two broad historical periods may be justified by the appearance of new cultural phenomena that profoundly modified the character of early modern alchemical poetry: the ever-increasing importance of the prisca theologia, the alchemical interpretation of ancient mythology, and the rise of neo-Latin humanist poetry. Although early modern alchemy was marked by the appearance of new doctrines (notably the alchemical spiritus mundi and Paracelsianism), alchemical poetry was only superficially modified by criteria of a scientific nature, which therefore appear to be of lesser importance. This study falls into two parts. Part I provides a descriptive survey of extant poetry, and in Part II the results of the survey are analysed in order to highlight such distinctive features as the function of alchemical poetry, the influence of the book market on its evolution, its doctrinal content, and the question of whether any theory of alchemical poetry ever emerged. Part II is accompanied by an index of the authors and works cited in both parts.

  7. Profile of the Romanian hypertensive patient data from SEPHAR II study.

    Science.gov (United States)

    Dorobanţu, Maria; Darabont, Roxana; Ghiorghe, S; Babes, K; Pop, Dana; Toma, Daciana; Vasilescu, Maria; Dobreanu, Minodora; Tăutu, Oana

    2012-01-01

    The objective of this paper is to present the profile of the Romanian hypertensive patient as revealed by the analysis of hypertensive subjects from SEPHAR II survey. A total number of 798 hypertensive subjects identified by SEPHAR II survey were analyzed in terms of socio-demographic characteristics, cardiovascular risk factors, subclinical target organ damage, established target organ disease, total CV risk and HT awareness, treatment and control. The profile of the Romanian hypertensive patients was built using the mod of every above mentioned target variables. The majority of hypertensive subjects were females (54.9%), mean age of 57.42 +/- 13.38 years, coming from the South region (17.8%), living in urban areas (59.5%) and aware of their condition (69.5%), associating most often other 4 CV risk factors among which physical inactivity (67.3%), visceral obesity (60.4%) and hypercholesterolemia (61.3%) are the most prevalent, having therefore a very high added CV risk (60.3%). Despite the widespread use of at least 2 antihypertensive drugs (72.3%), an effective treatment was recorded only in a quarter of treated hypertensives. The profile of Romanian Hypertensive patient is: middle aged female living in urban area of the South region of the country, with secondary education and a low average income, sedentary lifestyle, nonsmoker and aware of BP values, having visceral obesity, a high total cholesterol and LDL-cholesterol levels and normal HDL-cholesterol and triglyceride levels, having metabolic syndrome, nondiabetic and associating 4 other cardiovascular risk factors and therefore having a high added cardiovascular risk.

  8. Evaluation of the aerosol vertical distribution in global aerosol models through comparison against CALIOP measurements: AeroCom phase II results: AEROSOL PROFILES IN AEROCOM II GCM

    Energy Technology Data Exchange (ETDEWEB)

    Koffi, Brigitte [European Commission, Joint Research Centre, Institute for Environment and Sustainability, Ispra Italy; Schulz, Michael [Norwegian Meteorological Institute, Oslo Norway; Bréon, François-Marie [Laboratoire des Sciences du Climat et de l' Environnement, Gif-sur-Yvette France; Dentener, Frank [European Commission, Joint Research Centre, Institute for Environment and Sustainability, Ispra Italy; Steensen, Birthe Marie [Norwegian Meteorological Institute, Oslo Norway; Griesfeller, Jan [Norwegian Meteorological Institute, Oslo Norway; Winker, David [NASA Langley Research Center, MS/475, Hampton Virginia USA; Balkanski, Yves [Laboratoire des Sciences du Climat et de l' Environnement, Gif-sur-Yvette France; Bauer, Susanne E. [Center for Climate Systems Research, Columbia University, New York New York USA; NASA Goddard Institute for Space Studies, New York New York USA; Bellouin, Nicolas [Department of Meteorology, University of Reading, Reading UK; Berntsen, Terje [Department of Geosciences, University of Oslo, Oslo Norway; Center for International Climate and Environmental Research-Oslo (CICERO), Oslo Norway; Bian, Huisheng [NASA Goddard Space Flight Center, Greenbelt Maryland USA; Joint Center for Earth Systems Technology, University of Maryland Baltimore County, Baltimore Country Maryland USA; Chin, Mian [NASA Goddard Space Flight Center, Greenbelt Maryland USA; Diehl, Thomas [European Commission, Joint Research Centre, Institute for Environment and Sustainability, Ispra Italy; Easter, Richard [Pacific Northwest National Laboratory, Richland Washington USA; Ghan, Steven [Pacific Northwest National Laboratory, Richland Washington USA; Hauglustaine, Didier A. [Laboratoire des Sciences du Climat et de l' Environnement, Gif-sur-Yvette France; Iversen, Trond [Norwegian Meteorological Institute, Oslo Norway; Department of Geosciences, University of Oslo, Oslo Norway; Kirkevåg, Alf [Norwegian Meteorological Institute, Oslo Norway; Liu, Xiaohong [Pacific Northwest National Laboratory, Richland Washington USA; Now at University of Wyoming, Laramie Wyoming USA; Lohmann, Ulrike [ETH-Zentrum, Zürich Switzerland; Myhre, Gunnar [Center for International Climate and Environmental Research-Oslo (CICERO), Oslo Norway; Rasch, Phil [NASA Goddard Space Flight Center, Greenbelt Maryland USA; Seland, Øyvind [Norwegian Meteorological Institute, Oslo Norway; Skeie, Ragnhild B. [Center for International Climate and Environmental Research-Oslo (CICERO), Oslo Norway; Steenrod, Stephen D. [NASA Goddard Space Flight Center, Greenbelt Maryland USA; Stier, Philip [Department of Physics, University of Oxford, Oxford UK; Tackett, Jason [Science Systems and Applications, Inc., Hampton Virginia USA; Takemura, Toshihiko [Research Institute for Applied Mechanics, Kyushu University, Fukuoka Japan; Tsigaridis, Kostas [Center for Climate Systems Research, Columbia University, New York New York USA; NASA Goddard Institute for Space Studies, New York New York USA; Vuolo, Maria Raffaella [Laboratoire des Sciences du Climat et de l' Environnement, Gif-sur-Yvette France; Now at National Institute for Agronomic Research, Thiverval-Grignon France; Yoon, Jinho [Pacific Northwest National Laboratory, Richland Washington USA; Now at Gwangju Institute of Science and Technology, Gwangju Korea; Zhang, Kai [Pacific Northwest National Laboratory, Richland Washington USA; Max Planck Institute for Meteorology, Hamburg Germany

    2016-06-27

    The ability of eleven models in simulating the aerosol vertical distribution from regional to global scales, as part of the second phase of the AeroCom model inter-comparison initiative (AeroCom II) is assessed and compared to results of the first phase. The evaluation is performed using a global monthly gridded dataset of aerosol extinction profiles built on purpose from the CALIOP (Cloud-Aerosol Lidar with Orthogonal Polarization) Layer Product 3.01. Results over 12 sub-continental regions show that five models improved whereas three degraded in reproducing the Zα 0-6 km mean extinction height diagnostic, which is computed over the 0-6 km altitude range for each studied region and season. While the models’ performance remains highly variable, it has generally improved in terms of inter-regional diversity and seasonality. The biases in Zα 0-6 km have notably decreased in the U.S. and European industrial and downwind maritime regions, whereas the timing of the Zα 0-6 km peak season has improved for all but two models. However, most of the models now show a Zα 0-6 km underestimation over land, notably in the dust and biomass burning regions in Asia and Africa. At global scale, the AeroCom II models better reproduce the Zα 0-6 km latitudinal variability over ocean than over land. Hypotheses for the (changes in the) the performance of the individual models and for the inter-model diversity are discussed. We also provide an analysis of the CALIOP limitations and uncertainties that can contribute to the differences between the simulations and observations.

  9. A legacy of struggle: the OSHA ergonomics standard and beyond, Part II.

    Science.gov (United States)

    Delp, Linda; Mojtahedi, Zahra; Sheikh, Hina; Lemus, Jackie

    2014-11-01

    The OSHA ergonomics standard issued in 2000 was repealed within four months through a Congressional resolution that limits future ergonomics rulemaking. This section continues the conversation initiated in Part I, documenting a legacy of struggle for an ergonomics standard through the voices of eight labor, academic, and government key informants. Part I summarized important components of the standard; described the convergence of labor activism, research, and government action that laid the foundation for a standard; and highlighted the debates that characterized the rulemaking process. Part II explores the anti-regulatory political landscape of the 1990s, as well as the key opponents, power dynamics, and legal maneuvers that led to repeal of the standard. This section also describes the impact of the ergonomics struggle beyond the standard itself and ends with a discussion of creative state-level policy initiatives and coalition approaches to prevent work-related musculoskeletal disorders (WMSDs) in today's sociopolitical context.

  10. A Lagrangian variational formulation for nonequilibrium thermodynamics. Part II: Continuum systems

    Science.gov (United States)

    Gay-Balmaz, François; Yoshimura, Hiroaki

    2017-01-01

    Part I of this paper introduced a Lagrangian variational formulation for nonequilibrium thermodynamics of discrete systems. This variational formulation extends Hamilton's principle to allow the inclusion of irreversible processes in the dynamics. The irreversibility is encoded into a nonlinear nonholonomic constraint given by the expression of entropy production associated to all the irreversible processes involved. In Part II, we develop this formulation for the case of continuum systems by extending the setting of Part I to infinite dimensional nonholonomic Lagrangian systems. The variational formulation is naturally expressed in the material representation, while its spatial version is obtained via a nonholonomic Lagrangian reduction by symmetry. The theory is illustrated with the examples of a viscous heat conducting fluid and its multicomponent extension including chemical reactions and mass transfer.

  11. Subseabed disposal program annual report, January-December 1980. Volume II. Appendices (principal investigator progress reports). Part 1

    Energy Technology Data Exchange (ETDEWEB)

    Hinga, K.R. (ed.)

    1981-07-01

    Volume II of the sixth annual report describing the progress and evaluating the status of the Subseabed Disposal Program contains the appendices referred to in Volume I, Summary and Status. Because of the length of Volume II, it has been split into two parts for publication purposes. Part 1 contains Appendices A-Q; Part 2 contains Appendices R-MM. Separate abstracts have been prepared for each appendix for inclusion in the Energy Data Base.

  12. Changes in soft tissue profile using functional appliances in the treatment of skeletal class II malocclusion

    Directory of Open Access Journals (Sweden)

    Stamenković Zorana

    2015-01-01

    Full Text Available Introduction. The effects of orthodontic treatment are considered to be successful if the facial harmony is achieved, while the structures of soft tissue profile are in harmony with skeletal structures of neurocranium and viscerocranium. In patients with skeletal distal bite caused by mandibular retrognathism, facial esthetics is disturbed often, in terms of pronounced convexity of the profile and change in the position and relationship of the lips. Objective. The aim of this study was to determine the extent of soft tissue profile changes in patients with skeletal Class II malocclusion treated with three different orthodontic appliances: Fränkel functional regulator type I (FR-I, Balters’ Bionator type I and Hotz appliance. Methods. The study included 60 patients diagnosed with skeletal Class II malocclusion caused by mandibular retrognathism, in the period of early mixed dentition. Each subgroup of 20 patients was treated with a variety of orthodontic appliances. On the lateral cephalogram, before and after treatment, the following parameters were analyzed: T angle, H angle, the height of the upper lip, the position of the upper and lower lip in relation to the esthetic line. Within the statistical analysis the mean, maximum, minimum, standard deviation, coefficient of variation, two-factor analysis of variance with repeated measures and the factor analysis of variance were calculated using ANOVA, Bonferroni test and Student’s t-test. Results. A significant decrease of angles T and H was noticed in the application of FR-I, from 21.60° to 17.15°, and from 16.45° to 13.40° (p<0.001. FR-I decreased the height of the upper lip from 26.15 mm to 25.85 mm, while Hotz appliance and Balters’ Bionator type I increased the height of the upper lip, thereby deteriorating esthetics of the patient. Conclusion. All used orthodontic appliances lead to changes in soft tissue profile in terms of improving facial esthetics, with the most distinctive

  13. Photometry of Type II Cepheid Candidates from the Northern Part of the All Sky Automated Survey

    Science.gov (United States)

    Schmidt, Edward G.; Hemen, Brian; Rogalla, Danielle; Thacker-Lynn, Lauren

    2009-06-01

    We have obtained VR photometry of 282 Cepheid variable star candidates from the northern part of the All Sky Automated Survey (ASAS). These together with data from the ASAS and the Northern Sky Variability Survey (NSVS) were used to redetermine the periods of the stars. We divided the stars into four groups based on location in a plot of mean color, langV-Rrang, versus period. Two of the groups fell within the region of the diagram containing known type II Cepheids and yielded 14 new highly probable type II Cepheids. The properties of the remaining stars in these two groups are discussed but their nature remains uncertain. Unexplained differences exist between the sample of stars studied here and a previous sample drawn from the NSVS by Akerlof et al. This suggests serious biases in the identification of variables in different surveys.

  14. PIC Simulations in Low Energy Part of PIP-II Proton Linac

    Energy Technology Data Exchange (ETDEWEB)

    Romanov, Gennady

    2014-07-01

    The front end of PIP-II linac is composed of a 30 keV ion source, low energy beam transport line (LEBT), 2.1 MeV radio frequency quadrupole (RFQ), and medium energy beam transport line (MEBT). This configuration is currently being assembled at Fermilab to support a complete systems test. The front end represents the primary technical risk with PIP-II, and so this step will validate the concept and demonstrate that the hardware can meet the specified requirements. SC accelerating cavities right after MEBT require high quality and well defined beam after RFQ to avoid excessive particle losses. In this paper we will present recent progress of beam dynamic study, using CST PIC simulation code, to investigate partial neutralization effect in LEBT, halo and tail formation in RFQ, total emittance growth and beam losses along low energy part of the linac.

  15. Zn(II, Mn(II and Sr(II Behavior in a Natural Carbonate Reservoir System. Part II: Impact of Geological CO2 Storage Conditions

    Directory of Open Access Journals (Sweden)

    Auffray B.

    2016-07-01

    Full Text Available Some key points still prevent the full development of geological carbon sequestration in underground formations, especially concerning the assessment of the integrity of such storage. Indeed, the consequences of gas injection on chemistry and petrophysical properties are still much discussed in the scientific community, and are still not well known at either laboratory or field scale. In this article, the results of an experimental study about the mobilization of Trace Elements (TE during CO2 injection in a reservoir are presented. The experimental conditions range from typical storage formation conditions (90 bar, supercritical CO2 to shallower conditions (60 and 30 bar, CO2 as gas phase, and consider the dissolution of the two carbonates, coupled with the sorption of an initial concentration of 10−5 M of Zn(II, and the consequent release in solution of Mn(II and Sr(II. The investigation goes beyond the sole behavior of TE in the storage conditions: it presents the specific behavior of each element with respect to the pressure and the natural carbonate considered, showing that different equilibrium concentrations are to be expected if a fluid with a given concentration of TE leaks to an upper formation. Even though sorption is evidenced, it does not balance the amount of TE released by the dissolution process. The increase in porosity is clearly evidenced as a linear function of the CO2 pressure imposed for the St-Emilion carbonate. For the Lavoux carbonate, this trend is not confirmed by the 90 bar experiment. A preferential dissolution of the bigger family of pores from the preexisting porosity is observed in one of the samples (Lavoux carbonate while the second one (St-Emilion carbonate presents a newly-formed family of pores. Both reacted samples evidence that the pore network evolves toward a tubular network type.

  16. Comorbidity of psychiatric disorders and personality profiles of American World War II prisoners of war.

    Science.gov (United States)

    Engdahl, B E; Speed, N; Eberly, R E; Schwartz, J

    1991-04-01

    To characterize the effects of trauma sustained more than 40 years ago, prevalence of psychiatric disorders and personality dimensions were examined in a sample of 62 former World War II POWs. The negative effects of their experiences are reflected in their multiple lifetime diagnoses and in their current personality profiles. Fifty percent met DSM-III posttraumatic stress disorder (PTSD) criteria within 1 year of release; 18 (29%) continued to meet the criteria 40 years later at examination (chronic PTSD). A lifetime diagnosis of generalized anxiety disorder was found for over half the entire sample; in 42% of those who never had PTSD, 38% of those with recovery from PTSD, and 94% of those with chronic PTSD. Ten percent of those without a PTSD diagnosis had experienced a depressive disorder, as had 23% of those with recovery from PTSD and 61% of the POWs with chronic PTSD. The combination of depressive and anxiety disorders also was frequent in the total sample (61%). Current MMPIs of three groups with psychiatric diagnosis were compared with those of POWs who had no diagnoses and with a group of Minnesota normal men. Profile elevations for the groups, from highest to lowest, were: POWs with chronic PTSD, POWs with recovery from PTSD, POWs with other psychiatric diagnoses, POWs with no disorders, and Minnesota normal men. Symptoms of anxiety, depression, and somatic concerns combined with the personality styles of suppression and denial characterize the current adjustment of negatively affected POWs.

  17. Tracer concentration profiles measured in central London as part of the REPARTEE campaign

    Directory of Open Access Journals (Sweden)

    D. Martin

    2011-01-01

    Full Text Available There have been relatively few tracer experiments carried out that have looked at vertical plume spread in urban areas. In this paper we present results from two tracer (cyclic perfluorocarbon experiments carried out in 2006 and 2007 in central London centred on the BT Tower as part of the REPARTEE (Regent's Park and Tower Environmental Experiment campaign. The height of the tower gives a unique opportunity to study vertical dispersion profiles and transport times in central London. Vertical gradients are contrasted with the relevant Pasquill stability classes. Estimation of lateral advection and vertical mixing times are made and compared with previous measurements. Data are then compared with a simple operational dispersion model and contrasted with data taken in central London as part of the DAPPLE campaign. This correlates dosage with non-dimensionalised distance from source. Such analyses illustrate the feasibility of the use of these empirical correlations over these prescribed distances in central London.

  18. Sizes of flaring kernels in various parts of the Hα line profile

    Directory of Open Access Journals (Sweden)

    K. Radziszewski

    2008-10-01

    Full Text Available In this paper we present new results of spectra-photometrical investigations of the flaring kernels' sizes and their intensities measured simultaneously in various parts of the Hα line profile. Our investigations were based on the very high temporal resolution spectral-imaging observations of the solar flares collected with Large Coronagraph (LC, Multi-channel Subtractive Double Pass Spectrograph and Solar Eclipse Coronal Imaging System (MSDP-SECIS at Białkow Observatory (University of Wrocław, Poland.

    We have found that the areas of the investigated individual flaring kernels vary in time and in wavelengths, as well as the intensities and areas of the Hα flaring kernels decreased systematically when observed in consecutive wavelengths toward the wings of the Hα line. Our result could be explained as an effect of the cone-shaped lower parts of the magnetic loops channeling high energy particle beams exciting chromospheric plasma.

  19. Optimal recombination in genetic algorithms for combinatorial optimization problems: Part II

    Directory of Open Access Journals (Sweden)

    Eremeev Anton V.

    2014-01-01

    Full Text Available This paper surveys results on complexity of the optimal recombination problem (ORP, which consists in finding the best possible offspring as a result of a recombination operator in a genetic algorithm, given two parent solutions. In Part II, we consider the computational complexity of ORPs arising in genetic algorithms for problems on permutations: the Travelling Salesman Problem, the Shortest Hamilton Path Problem and the Makespan Minimization on Single Machine and some other related problems. The analysis indicates that the corresponding ORPs are NP-hard, but solvable by faster algorithms, compared to the problems they are derived from.

  20. Analysis of the phospholipid profile of metaphase II mouse oocytes undergoing vitrification.

    Directory of Open Access Journals (Sweden)

    Jaehun Jung

    Full Text Available Oocyte freezing confers thermal and chemical stress upon the oolemma and various other intracellular structures due to the formation of ice crystals. The lipid profiles of oocytes and embryos are closely associated with both, the degrees of their membrane fluidity, as well as the degree of chilling and freezing injuries that may occur during cryopreservation. In spite of the importance of lipids in the process of cryopreservation, the phospholipid status in oocytes and embryos before and after freezing has not been investigated. In this study, we employed mass spectrometric analysis to examine if vitrification has an effect on the phospholipid profiles of mouse oocytes. Freshly prepared metaphase II mouse oocytes were vitrified using copper grids and stored in liquid nitrogen for 2 weeks. Fresh and vitrified-warmed oocytes were subjected to phospholipid extraction procedure. Mass spectrometric analyses revealed that multiple species of phospholipids are reduced in vitrified-warmed oocytes. LIFT analyses identified 31 underexpressed and 5 overexpressed phospholipids in vitrified mouse oocytes. The intensities of phosphatidylinositol (PI {18∶2/16∶0} [M-H]- and phosphatidylglycerol (PG {14∶0/18∶2} [M-H]- were decreased the most with fold changes of 30.5 and 19.1 in negative ion mode, respectively. Several sphingomyelins (SM including SM {d38∶3} [M+H]+ and SM {d34∶0} [M+K]+ were decreased significantly in positive ion mode. Overall, the declining trend of multiple phospholipids demonstrates that vitrification has a marked effect on phospholipid profiles of oocytes. These results show that the identified phospholipids can be used as potential biomarkers of oocyte undergoing vitrification and will allow for the development of strategies to preserve phospholipids during oocyte cryopreservation.

  1. A framework for biodynamic feedthrough analysis--part II: validation and application.

    Science.gov (United States)

    Venrooij, Joost; van Paassen, Marinus M; Mulder, Mark; Abbink, David A; Mulder, Max; van der Helm, Frans C T; Bulthoff, Heinrich H

    2014-09-01

    Biodynamic feedthrough (BDFT) is a complex phenomenon, that has been studied for several decades. However, there is little consensus on how to approach the BDFT problem in terms of definitions, nomenclature, and mathematical descriptions. In this paper, the framework for BDFT analysis, as presented in Part I of this dual publication, is validated and applied. The goal of this framework is twofold. First of all, it provides some common ground between the seemingly large range of different approaches existing in BDFT literature. Secondly, the framework itself allows for gaining new insights into BDFT phenomena. Using recently obtained measurement data, parts of the framework that were not already addressed elsewhere, are validated. As an example of a practical application of the framework, it will be demonstrated how the effects of control device dynamics on BDFT can be understood and accurately predicted. Other ways of employing the framework are illustrated by interpreting the results of three selected studies from the literature using the BDFT framework. The presentation of the BDFT framework is divided into two parts. This paper, Part II, addresses the validation and application of the framework. Part I, which is also published in this journal issue, addresses the theoretical foundations of the framework. The work is presented in two separate papers to allow for a detailed discussion of both the framework's theoretical background and its validation.

  2. History of spine biomechanics: part II--from the Renaissance to the 20th century.

    Science.gov (United States)

    Naderi, Sait; Andalkar, Niteen; Benzel, Edward C

    2007-02-01

    Spine biomechanics provide the foundation for the disciplines of spine medicine and spine surgery. Although modern spine biomechanics emerged during the second half of the last century, it has many ancient, medieval, and post-Renaissance roots. In Part I of this series, the ancient and medieval roots of spine biomechanics were reviewed. In Part II, the effects of post-Renaissance scientists on the development of modern spine biomechanics, as well as the studies on gait, bone, and muscles performed before the 20th century, are reviewed. Subsequently, war-related studies performed in the 20th century contributed to the formation of modern biomechanics. The first biomechanics-related organizations and scientific publications did not emerge until the second half of the 20th century. These events provided the final bricks in the foundation that facilitated the emergence of modern spine biomechanics research.

  3. Practical application of new technologies for melanoma diagnosis: Part II. Molecular approaches.

    Science.gov (United States)

    March, Jordon; Hand, Matthew; Truong, Amanda; Grossman, Douglas

    2015-06-01

    The criterion standard for diagnosing cutaneous melanoma continues to be histologic examination. However, classifying some melanocytic lesions by conventional microscopy can be problematic if they exhibit some architectural or morphologic characteristics of both nevus and melanoma. Moreover, histologic appearance does not always predict biologic behavior. There is therefore a need and opportunity to develop new technologies that can facilitate the histologic diagnosis of melanoma and potentially help distinguish lesions with a lesser or greater risk of metastasis. In part II of this 2-part continuing medical education article, we will review the molecular technologies currently available for facilitating melanoma diagnosis, including comparative genomic hybridization, fluorescence in situ hybridization, and epidermal genetic retrieval. Our goal is to provide the clinician with an up to date understanding of these molecular approaches so that they can be applied to their management of challenging melanocytic lesions. Copyright © 2015 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

  4. Exploring Cancer Therapeutics with Natural Products from African Medicinal Plants, Part II: Alkaloids, Terpenoids and Flavonoids.

    Science.gov (United States)

    Nwodo, Justina N; Ibezim, Akachukwu; Simoben, Conrad V; Ntie-Kang, Fidele

    2016-01-01

    Cancer stands as second most common cause of disease-related deaths in humans. Resistance of cancer to chemotherapy remains challenging to both scientists and physicians. Medicinal plants are known to contribute significantly to a large population of Africa, which is to a very large extent linked to folkloric claims which is part of their livelihood. In this review paper, the potential of naturally occurring anti-cancer agents from African flora has been explored, with suggested modes of action, where such data is available. Literature search revealed plant-derived compounds from African flora showing anti-cancer and/or cytotoxic activities, which have been tested in vitro and in vivo. This corresponds to 400 compounds (from mildly active to very active) covering various compound classes. However, in this part II, we only discussed the three major compound classes which are: flavonoids, alkaloids and terpenoids.

  5. Advances in Unsteady Boundary Layer Transition Research, Part II: Experimental Verification

    Directory of Open Access Journals (Sweden)

    M. T. Schobeiri

    2003-01-01

    Full Text Available This two-part article presents recent advances in boundary layer research into the unsteady boundary layer transition modeling and its validation. This, Part II, deals with the results of an inductive approach based on comprehensive experimental and theoretical studies of unsteady wake flow and unsteady boundary layer flow. The experiments were performed on a curved plate at a zero streamwise pressure gradient under periodic unsteady wake flow, in which the frequency of the periodic unsteady flow was varied. To validate the model, systematic experimental investigations were performed on the suction and pressure surfaces of turbine blades integrated into a high-subsonic cascade test facility, which was designed for unsteady boundary layer investigations. The analysis of the experiment's results and comparison with the model's prediction confirm the validity of the model and its ability to predict accurately the unsteady boundary layer transition.

  6. Biology and Mechanics of Blood Flows Part II: Mechanics and Medical Aspects

    CERN Document Server

    Thiriet, Marc

    2008-01-01

    Biology and Mechanics of Blood Flows presents the basic knowledge and state-of-the-art techniques necessary to carry out investigations of the cardiovascular system using modeling and simulation. Part II of this two-volume sequence, Mechanics and Medical Aspects, refers to the extraction of input data at the macroscopic scale for modeling the cardiovascular system, and complements Part I, which focuses on nanoscopic and microscopic components and processes. This volume contains chapters on anatomy, physiology, continuum mechanics, as well as pathological changes in the vasculature walls including the heart and their treatments. Methods of numerical simulations are given and illustrated in particular by application to wall diseases. This authoritative book will appeal to any biologist, chemist, physicist, or applied mathematician interested in the functioning of the cardiovascular system.

  7. Part I: Sound color in the music of Gyorgy Kurtag, Part II: "Leopard's Path," thirteen visions for chamber ensemble

    Science.gov (United States)

    Iachimciuc, Igor

    The dissertation is in two parts, a theoretical study and a musical composition. In Part I the music of Gyorgy Kurtag is analyzed from the point of view of sound color. A brief description of what is understood by the term sound color, and various ways of achieving specific coloristic effects, are presented in the Introduction. An examination of Kurtag's approaches to the domain of sound color occupies the chapters that follow. The musical examples that are analyzed are selected from Kurtag's different compositional periods, showing a certain consistency in sound color techniques, the most important of which are already present in the String Quartet, Op. 1. The compositions selected for analysis are written for different ensembles, but regardless of the instrumentation, certain principles of the formation and organization of sound color remain the same. Rather than relying on extended instrumental techniques, Kurtag creates a large variety of sound colors using traditional means such as pitch material, register, density, rhythm, timbral combinations, dynamics, texture, spatial displacement of the instruments, and the overall musical context. Each sound color unit in Kurtag's music is a separate entity, conceived as a complete microcosm. Sound color units can either be juxtaposed as contrasting elements, forming sound color variations, or superimposed, often resulting in a Klangfarbenmelodie effect. Some of the same gestural figures (objets trouves) appear in different compositions, but with significant coloristic modifications. Thus, the principle of sound color variations is not only a strong organizational tool, but also a characteristic stylistic feature of the music of Gyorgy Kurtag. Part II, Leopard's Path (2010), for flute, clarinet, violin, cello, cimbalom, and piano, is an original composition inspired by the painting of Jesse Allen, a San Francisco based artist. The composition is conceived as a cycle of thirteen short movements. Ten of these movements are

  8. [Correction of refractive errors in patients with strabismus. Part II. Clinical aspects of refraction--spectacle and contact lens correction].

    Science.gov (United States)

    Tokarz-Sawińska, Ewa

    2012-01-01

    In Part II the clinical aspects of refractive errors such as hyperopia, myopia, astigmatism, anisometropia, aphakia and unilateral pseudophakia have been described along with strabismus and prism and spectacle correction allowing additionally proper visual alignment.

  9. Storage time does not modify the gene expression profile of cryopreserved human metaphase II oocytes.

    Science.gov (United States)

    Stigliani, Sara; Moretti, Stefano; Anserini, Paola; Casciano, Ida; Venturini, Pier Luigi; Scaruffi, Paola

    2015-11-01

    Does storage time have any impact on the transcriptome of slowly frozen cryopreserved human metaphase II (MII) oocytes? The length of cryostorage has no effect on the gene expression profile of human MII oocytes. Oocyte cryopreservation is a widely used technique in IVF for storage of surplus oocytes, as well as for fertility preservation (i.e. women undergoing gonadotoxic therapies) and oocyte donation programs. Although cryopreservation has negative impacts on oocyte physiology and it is associated with decrease of transcripts, no experimental data about the effect of storage time on the oocyte molecular profile are available to date. This study included 27 women, ≤38 years aged, without any ovarian pathology, undergoing IVF treatment. Surplus MII oocytes were donated after written informed consent. A total of 31 non-cryopreserved oocytes and 68 surviving slow-frozen/rapid-thawed oocytes (32 oocytes cryostored for 3 years and 36 cryostored for 6 years) were analyzed. Pools of ≈10 oocytes for each group were prepared. Total RNA was extracted from each pool, amplified, labeled and hybridized on oligonucleotide microarrays. Analyses were performed by R software using the limma package. Comparison of gene expression profiles between surviving thawed oocytes after 3 and 6 years of storage in liquid nitrogen found no differently expressed genes. The expression profiles of cryopreserved MII oocytes significantly differed from those of non-cryopreserved oocytes in 107 probe sets corresponding to 73 down-regulated and 29 up-regulated unique transcripts. Gene Ontology analysis by DAVID bioinformatics resource disclosed that cryopreservation deregulates genes involved in oocyte function and early embryo development, such as chromosome organization, RNA splicing and processing, cell cycle, cellular response to DNA damage and to stress, DNA repair, calcium ion binding, malate dehydrogenase activity and mitochondrial activity. Among the probes significantly up-regulated in

  10. Mineral resources of parts of the Departments of Antioquia and Caldas, Zone II, Colombia

    Science.gov (United States)

    Hall, R.B.; Feininger, Tomas; Barrero, L.; Dario, Rico H.; ,; Alvarez, A.

    1970-01-01

    The mineral resources of an area of 40,000 sq km, principally in the Department of Antioquia, but including small parts of the Departments of Caldas, C6rdoba, Risaralda, and Tolima, were investigated during the period 1964-68. The area is designated Zone II by the Colombian Inventario Minero Nacional(lMN). The geology of approximately 45 percent of this area, or 18,000 sq km, has been mapped by IMN. Zone II has been a gold producer for centuries, and still produces 75 percent of Colombia's gold. Silver is recovered as a byproduct. Ferruginous laterites have been investigated as potential sources of iron ore but are not commercially exploitable. Nickeliferous laterite on serpentinite near Ure in the extreme northwest corner of the Zone is potentially exploitable, although less promising than similar laterites at Cerro Matoso, north of the Zone boundary. Known deposits of mercury, chromium, manganese, and copper are small and have limited economic potentia1. Cement raw materials are important among nonmetallic resources, and four companies are engaged in the manufacture of portland cement. The eastern half of Zone II contains large carbonate rock reserves, but poor accessibility is a handicap to greater development at present. Dolomite near Amalfi is quarried for the glass-making and other industries. Clay saprolite is abundant and widely used in making brick and tiles in backyard kilns. Kaolin of good quality near La Union is used by the ceramic industry. Subbituminous coal beds of Tertiary are an important resource in the western part of the zone and have good potential for greater development. Aggregate materials for construction are varied and abundant. Deposits of sodic feldspar, talc, decorative stone, and silica are exploited on a small scale. Chrysotils asbestos deposits north of Campamento are being developed to supply fiber for Colombia's thriving asbestos-cement industry, which is presently dependent upon imported fiber. Wollastonite and andalusite are

  11. Analysis of Radionuclide Releases from the Fukushima Dai-ichi Nuclear Power Plant Accident Part II

    Science.gov (United States)

    Achim, Pascal; Monfort, Marguerite; Le Petit, Gilbert; Gross, Philippe; Douysset, Guilhem; Taffary, Thomas; Blanchard, Xavier; Moulin, Christophe

    2014-03-01

    The present part of the publication (Part II) deals with long range dispersion of radionuclides emitted into the atmosphere during the Fukushima Dai-ichi accident that occurred after the March 11, 2011 tsunami. The first part (Part I) is dedicated to the accident features relying on radionuclide detections performed by monitoring stations of the Comprehensive Nuclear Test Ban Treaty Organization network. In this study, the emissions of the three fission products Cs-137, I-131 and Xe-133 are investigated. Regarding Xe-133, the total release is estimated to be of the order of 6 × 1018 Bq emitted during the explosions of units 1, 2 and 3. The total source term estimated gives a fraction of core inventory of about 8 × 1018 Bq at the time of reactors shutdown. This result suggests that at least 80 % of the core inventory has been released into the atmosphere and indicates a broad meltdown of reactor cores. Total atmospheric releases of Cs-137 and I-131 aerosols are estimated to be 1016 and 1017 Bq, respectively. By neglecting gas/particulate conversion phenomena, the total release of I-131 (gas + aerosol) could be estimated to be 4 × 1017 Bq. Atmospheric transport simulations suggest that the main air emissions have occurred during the events of March 14, 2011 (UTC) and that no major release occurred after March 23. The radioactivity emitted into the atmosphere could represent 10 % of the Chernobyl accident releases for I-131 and Cs-137.

  12. Two-loop renormalization in the standard model, part II. Renormalization procedures and computational techniques

    Energy Technology Data Exchange (ETDEWEB)

    Actis, S. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Passarino, G. [Torino Univ. (Italy). Dipt. di Fisica Teorica; INFN, Sezione di Torino (Italy)

    2006-12-15

    In part I general aspects of the renormalization of a spontaneously broken gauge theory have been introduced. Here, in part II, two-loop renormalization is introduced and discussed within the context of the minimal Standard Model. Therefore, this paper deals with the transition between bare parameters and fields to renormalized ones. The full list of one- and two-loop counterterms is shown and it is proven that, by a suitable extension of the formalism already introduced at the one-loop level, two-point functions suffice in renormalizing the model. The problem of overlapping ultraviolet divergencies is analyzed and it is shown that all counterterms are local and of polynomial nature. The original program of 't Hooft and Veltman is at work. Finite parts are written in a way that allows for a fast and reliable numerical integration with all collinear logarithms extracted analytically. Finite renormalization, the transition between renormalized parameters and physical (pseudo-)observables, are discussed in part III where numerical results, e.g. for the complex poles of the unstable gauge bosons, are shown. An attempt is made to define the running of the electromagnetic coupling constant at the two-loop level. (orig.)

  13. Seismic risk analysis for General Electric Plutonium Facility, Pleasanton, California. Final report, part II

    Energy Technology Data Exchange (ETDEWEB)

    1980-06-27

    This report is the second of a two part study addressing the seismic risk or hazard of the special nuclear materials (SNM) facility of the General Electric Vallecitos Nuclear Center at Pleasanton, California. The Part I companion to this report, dated July 31, 1978, presented the seismic hazard at the site that resulted from exposure to earthquakes on the Calaveras, Hayward, San Andreas and, additionally, from smaller unassociated earthquakes that could not be attributed to these specific faults. However, while this study was in progress, certain additional geologic information became available that could be interpreted in terms of the existance of a nearby fault. Although substantial geologic investigations were subsequently deployed, the existance of this postulated fault, called the Verona Fault, remained very controversial. The purpose of the Part II study was to assume the existance of such a capable fault and, under this assumption, to examine the loads that the fault could impose on the SNM facility. This report first reviews the geologic setting with a focus on specifying sufficient geologic parameters to characterize the postulated fault. The report next presents the methodology used to calculate the vibratory ground motion hazard. Because of the complexity of the fault geometry, a slightly different methodology is used here compared to the Part I report. This section ends with the results of the calculation applied to the SNM facility. Finally, the report presents the methodology and results of the rupture hazard calculation.

  14. Biological Activities and Phytochemical Profiles of Extracts from Different Parts of Bamboo (Phyllostachys pubescens

    Directory of Open Access Journals (Sweden)

    Akinobu Tanaka

    2014-06-01

    Full Text Available Besides being a useful building material, bamboo also is a potential source of bioactive substances. Although some studies have been performed to examine its use in terms of the biological activity, only certain parts of bamboo, especially the leaves or shoots, have been studied. Comprehensive and comparative studies among different parts of bamboo would contribute to a better understanding and application of this knowledge. In this study, the biological activities of ethanol and water extracts from the leaves, branches, outer culm, inner culm, knots, rhizomes and roots of Phyllostachys pubescens, the major species of bamboo in Japan, were comparatively evaluated. The phytochemical profiles of these extracts were tentatively determined by liquid chromatography-mass spectrometry (LC-MS analysis. The results showed that extracts from different parts of bamboo had different chemical compositions and different antioxidative, antibacterial and antiallergic activities, as well as on on melanin biosynthesis. Outer culm and inner culm were found to be the most important sources of active compounds. 8-C-Glucosylapigenin, luteolin derivatives and chlorogenic acid were the most probable compounds responsible for the anti-allergy activity of these bamboo extracts. Our study suggests the potential use of bamboo as a functional ingredient in cosmetics or other health-related products.

  15. Compliance with supportive periodontal therapy. Part II: Risk of non-compliance in a 10-year period.

    Science.gov (United States)

    Novaes, A B; Novaes, A B

    2001-01-01

    Supportive periodontal therapy (SPT) is needed for the success of periodontal therapy; however, patient compliance is poor. Part II of this study analyzes compliance during a 10-year period in an attempt to identify the profile of patients with a higher risk of becoming non-compliant. Data from the records of 874 patients from a private periodontal clinic who had completed active periodontal treatment up to 10 years before and had begun supportive periodontal therapy were analyzed for risk of non-compliance and compliance. The factors evaluated were gender (326 males and 548 females), type of therapy (surgical or non-surgical) and age ( or = 51 years old) and the association amongst them. In the period studied, compliance with SPT was 45.8%. Forty-three percent of males and 47% of females discontinued SPT. In the surgical group 43.9% were non-compliant and in the non-surgical group 53.2% were non-compliant. Fifty-nine percent of the patients or = 51 years of age that underwent non-surgical therapy were found to be of higher risk for non-compliance in the 10-year period studied.

  16. Apparel shopping behaviour – Part 2: Conceptual theoretical model, market segments, profiles and implications

    Directory of Open Access Journals (Sweden)

    R. Du Preez

    2003-10-01

    Full Text Available This article is based on the conceptual theoretical model developed in Part 1 of this series of articles. The objective of this research is to identify female apparel consumer market segments on the basis of differentiating lifestyles, shopping orientation, cultural consciousness, store patronage and demographics. These profiles are discussed in full and the implications thereof for retailers, marketers and researchers are highlighted. A new conceptual model is proposed and recommendations are made for further research. Opsomming Hierdie artikel word gebaseer op die konseptuele teoretiese model wat reeds in Deel 1 van hierdie artikelreeks ontwikkel is. Die doel van hierdie navorsing is om marksegmente van vroue klere-kopers te identifiseer na aanleiding van hulle lewenstyle, kooporiëntasie, kulturele bewustheid, winkelvoorkeurgedrag en demografie. Hierdie profiele word volledig beskryf en die implikasies van die verskillende profiele vir kleinhandelaars, bemarkers en navorsers word uitgelig. ’n Nuwe konseptuele model word voorgestel en aanbevelings vir verdere navorsing word gemaak.

  17. PHENOLIC PROFILE OF HONEYDEW HONEYS FROM THE NORTH-EAST PART OF ROMANIA

    Directory of Open Access Journals (Sweden)

    Mircea OROIAN

    2016-11-01

    Full Text Available The aim of this study is to determine the physicochemical (moisture content, pH, free acidity, electrical conductivity, colour (L*, a*, b*, chroma, hue angle, ash content, fructose and glucose content and to determine the phenolic profile (quercetin, apigenin, myricetin, isorhamnetin, kaempherol, caffeic acid, chrysin, galangin, luteolin, p-coumaric acid, gallic acid and pinocembrin of five samples of honeydew honeys from the North East part of Romania. The honey samples analysed respected the maximum allowable level of the moisture content, which is established by the European Union at 20%. The acidic nature of the honeydew is confirmed by the level of the pH and free acidity of the samples, and is influenced in principal by the organic acids; all the samples had a free acidity lower than 50 meq acid/kg. The honey colour is dark which is confirmed by the level of the CIE L*a*b* parameters (lower values of L*, a* and b*. The inverted sugar level (fructose and glucose content is higher than 60 g/ 100g, respecting the European Union directive. The phenolic profile of the honeydew samples do not presented one compound that can be considered a chemical marker, the major polyphenols presented into the honeydew honeys are quercetin and pinocembrin.

  18. Psychological Profile in a General Population in Central Part of Iran

    Directory of Open Access Journals (Sweden)

    Hamid Afshar

    2016-09-01

    Full Text Available Background: The description of demographic features and associated risk factors provides a perspective for the development of health and prevention policies for psychological screening or referrals. Thus, updated data on epidemiologic profile of depression and anxiety in the society are necessary. This study aims to describe the psychological profile of a general population in central Iran.Methods: This community-based, cross-sectional survey was performed as part of the SEPAHAN project (Study on the Epidemiology of Psychological‐Alimentary Health and Nutrition. The participants were working in 50 different centers across Isfahan Province, Iran. The data on 4628 adults who had completeddemographic questionnaires and psychological questionnaires for depression and anxiety, coping styles,and stressful life events were included in the analysis. The data collection tools were the Demographicinformation questionnaire, Hospital Anxiety and Depression Scale (HADS, Coping Strategies Scale(Cope, and Stressful Life Event (SLE questionnaire.Results: The frequency and intensity of all considered stressors were found to be significantly associated withboth depression and anxiety. Adaptive coping strategies were found to function as protective factors against bothdepression and anxiety. However, avoidance, as a maladaptive coping strategy, was found to be a risk factor.Conclusion: The present survey reveals that the prevalence of depression and anxiety was 28% and 14%,respectively. Scholastic education plays a protective role against both depression and anxiety. All coping strategies, except avoidance, function to protect against depression and anxiety.

  19. Compassionate care: enhancing physician-patient communication and education in dermatology: Part II: Patient education.

    Science.gov (United States)

    Hong, Judith; Nguyen, Tien V; Prose, Neil S

    2013-03-01

    Patient education is a fundamental part of caring for patients. A practice gap exists, where patients want more information, while health care providers are limited by time constraints or difficulty helping patients understand or remember. To provide patient-centered care, it is important to assess the needs and goals, health beliefs, and health literacy of each patient. This allows health care providers to individualize education for patients. The use of techniques, such as gaining attention, providing clear and memorable explanations, and assessing understanding through "teach-back," can improve patient education. Verbal education during the office visit is considered the criterion standard. However, handouts, visual aids, audiovisual media, and Internet websites are examples of teaching aids that can be used as an adjunct to verbal instruction. Part II of this 2-part series on patient-physician interaction reviews the importance and need for patient education along with specific guidelines and techniques that can be used. Copyright © 2012 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.

  20. The spectrum of oculocutaneous disease: Part II. Neoplastic and drug-related causes of oculocutaneous disease.

    Science.gov (United States)

    Day, Antoinette; Abramson, Amanda K; Patel, Mahir; Warren, Richard B; Menter, M Alan

    2014-05-01

    There are a multitude of diseases that commonly affect both the skin and the eye. Part II of this 2-part series reviews the oculocutaneous manifestations of neoplasms, both benign and malignant, and adverse drug reactions affecting the skin and the eye. Though rare, a number of neoplasms that primarily involve the skin, such as melanoma and basal cell carcinoma, can metastasize to the eye, leading to permanent damage if not properly treated. In addition, periocular neoplasms can irritate the conjunctiva and lid, reducing a patient's ability to see clearly. Neoplastic diseases, such as xeroderma pigmentosum, Sturge-Weber syndrome, and multiple myeloma, can also lead to permanent changes in the eye if not discovered and managed promptly. Furthermore, there are a multitude of drugs, including those commonly used by dermatologists, which can result in permanent damage to the eye. With proper knowledge of the ocular manifestations and treatment recommendations described in this 2-part series, dermatologists with the assistance of their ophthalmology colleagues can help avoid the complications, including permanent blindness, associated with infectious, inflammatory, genetic, neoplastic, and drug-related conditions. Copyright © 2014 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.

  1. From Constraints to Resolution Rules Part II : chains, braids, confluence and T&E

    Science.gov (United States)

    Berthier, Denis

    In this Part II, we apply the general theory developed in Part I to a detailed analysis of the Constraint Satisfaction Problem (CSP). We show how specific types of resolution rules can be defined. In particular, we introduce the general notions of a chain and a braid. As in Part I, these notions are illustrated in detail with the Sudoku example - a problem known to be NP-complete and which is therefore typical of a broad class of hard problems. For Sudoku, we also show how far one can go in "approximating" a CSP with a resolution theory and we give an empirical statistical analysis of how the various puzzles, corresponding to different sets of entries, can be classified along a natural scale of complexity. For any CSP, we also prove the confluence property of some Resolution Theories based on braids and we show how it can be used to define different resolution strategies. Finally, we prove that, in any CSP, braids have the same solving capacity as Trial-and-Error (T&E) with no guessing and we comment this result in the Sudoku case.

  2. Noncardiac findings on cardiac CT. Part II: spectrum of imaging findings.

    LENUS (Irish Health Repository)

    Killeen, Ronan P

    2012-02-01

    Cardiac computed tomography (CT) has evolved into an effective imaging technique for the evaluation of coronary artery disease in selected patients. Two distinct advantages over other noninvasive cardiac imaging methods include its ability to directly evaluate the coronary arteries and to provide a unique opportunity to evaluate for alternative diagnoses by assessing the extracardiac structures, such as the lungs and mediastinum, particularly in patients presenting with the chief symptom of acute chest pain. Some centers reconstruct a small field of view (FOV) cropped around the heart but a full FOV (from skin to skin in the area irradiated) is obtainable in the raw data of every scan so that clinically relevant noncardiac findings are identifiable. Debate in the scientific community has centered on the necessity for this large FOV. A review of noncardiac structures provides the opportunity to make alternative diagnoses that may account for the patient\\'s presentation or to detect important but clinically silent problems such as lung cancer. Critics argue that the yield of biopsy-proven cancers is low and that the follow-up of incidental noncardiac findings is expensive, resulting in increased radiation exposure and possibly unnecessary further testing. In this 2-part review we outline the issues surrounding the concept of the noncardiac read, looking for noncardiac findings on cardiac CT. Part I focused on the pros and cons for and against the practice of identifying noncardiac findings on cardiac CT. Part II illustrates the imaging spectrum of cardiac CT appearances of benign and malignant noncardiac pathology.

  3. Music in the exercise domain: a review and synthesis (Part II)

    Science.gov (United States)

    Karageorghis, Costas I.; Priest, David-Lee

    2011-01-01

    Since a 1997 review by Karageorghis and Terry, which highlighted the state of knowledge and methodological weaknesses, the number of studies investigating musical reactivity in relation to exercise has swelled considerably. In this two-part review paper, the development of conceptual approaches and mechanisms underlying the effects of music are explicated (Part I), followed by a critical review and synthesis of empirical work (spread over Parts I and II). Pre-task music has been shown to optimise arousal, facilitate task-relevant imagery and improve performance in simple motoric tasks. During repetitive, endurance-type activities, self-selected, motivational and stimulative music has been shown to enhance affect, reduce ratings of perceived exertion, improve energy efficiency and lead to increased work output. There is evidence to suggest that carefully selected music can promote ergogenic and psychological benefits during high-intensity exercise, although it appears to be ineffective in reducing perceptions of exertion beyond the anaerobic threshold. The effects of music appear to be at their most potent when it is used to accompany self-paced exercise or in externally valid conditions. When selected according to its motivational qualities, the positive impact of music on both psychological state and performance is magnified. Guidelines are provided for future research and exercise practitioners. PMID:22577473

  4. Constructions of Optical Queues With a Limited Number of Recirculations--Part II: Optimal Constructions

    CERN Document Server

    Huang, Xuan-Chao

    2010-01-01

    One of the main problems in all-optical packet-switched networks is the lack of optical buffers, and one feasible technology for the constructions of optical buffers is to use optical crossbar Switches and fiber Delay Lines (SDL). In this two-part paper, we consider SDL constructions of optical queues with a limited number of recirculations through the optical switches and the fiber delay lines. Such a problem arises from practical feasibility considerations. In Part I, we have proposed a class of greedy constructions for certain types of optical queues, including linear compressors, linear decompressors, and 2-to-1 FIFO multiplexers, and have shown that every optimal construction among our previous constructions of these types of optical queues under the constraint of a limited number of recirculations must be a greedy construction. In Part II, the present paper, we further show that there are at most two optimal constructions and give a simple algorithm to obtain the optimal construction(s). The main idea i...

  5. Sensitization Profile to Allergens in Patients Using Multi-Test II

    Science.gov (United States)

    Maniglia, Sergio Fabricio; Tsuru, Fernanda Miyoko; Santos, Victor Carvalho dos; Ueda, Denis Massatsugu

    2014-01-01

    Introduction Medical intervention in allergies has broadened its perspective, also focusing in the quality of life of patients. Patients are instructed, before using pharmacotherapy agents, to avoid the causal agent. Objective This study aims to analyze the sensitization profile of patients with allergic complaints and identify possible characteristics specific to each age group and gender. Methods A descriptive cross-sectional study included data collected from medical records (from Multi-Test II database, Lincoln Diagnostics Inc. Decatur, Illinois) of 1,912 patients who underwent skin prick test from March to October 2013. Patients were organized and analyzed according to gender, age, and results of the allergens subtypes tested. Results The study was composed of 1,912 patients (60% male and 40% female) of ages between 3 and 87 years. Positive tests were more prevalent in quantity and intensity with the mites Dermatophagoides pteronyssinus and Dermatophagoides farinae, each with 60% of the total analyzed. In second place were pollens, especially Dactylis glomerata and Festuca pratensis. Conclusion The female and male sexes were equally atopic. Fungi and epithelia of dog and cat were not considered potential aeroallergens that could cause symptoms. However, mites are common in Paraná, Brazil. Further studies regarding the pollens are needed, as this study result diverged from the literature. PMID:25992129

  6. Mechanical performance of carbon-epoxy laminates. Part II: quasi-static and fatigue tensile properties

    Directory of Open Access Journals (Sweden)

    José Ricardo Tarpani

    2006-06-01

    Full Text Available In Part II of this work, quasi-static tensile properties of four aeronautical grade carbon-epoxy composite laminates, in both the as-received and pre-fatigued states, have been determined and compared. Quasi-static mechanical properties assessed were tensile strength and stiffness, tenacity (toughness at the maximum load and for a 50% load drop-off. In general, as-molded unidirectional cross-ply carbon fiber (tape reinforcements impregnated with either standard or rubber-toughened epoxy resin exhibited the maximum performance. The materials also displayed a significant tenacification (toughening after exposed to cyclic loading, resulting from the increased stress (the so-called wear-in phenomenon and/or strain at the maximum load capacity of the specimens. With no exceptions, two-dimensional woven textile (fabric pre-forms fractured catastrophically under identical cyclic loading conditions imposed to the fiber tape architecture, thus preventing their residual properties from being determined.

  7. Putting microbes to work: dairy fermentation, cell factories and bioactive peptides. Part II: bioactive peptide functions.

    Science.gov (United States)

    Hayes, Maria; Stanton, Catherine; Fitzgerald, Gerald F; Ross, R Paul

    2007-04-01

    A variety of milk-derived biologically active peptides have been shown to exert both functional and physiological roles in vitro and in vivo, and because of this are of particular interest for food science and nutrition applications. Biological activities associated with such peptides include immunomodulatory, antibacterial, anti-hypertensive and opioid-like properties. Milk proteins are recognized as a primary source of bioactive peptides, which can be encrypted within the amino acid sequence of dairy proteins, requiring proteolysis for release and activation. Fermentation of milk proteins using the proteolytic systems of lactic acid bacteria is an attractive approach for generation of functional foods enriched in bioactive peptides given the low cost and positive nutritional image associated with fermented milk drinks and yoghurt. In Part II of this review, we focus on examples of milk-derived bioactive peptides and their associated health benefits, to illustrate the potential of this area for the design and improvement of future functional foods.

  8. CERN scientists take part in the Tevatron Run II performance review committee

    CERN Multimedia

    Maximilien Brice

    2002-01-01

    Tevatron Run II is under way at Fermilab, exploring the high-energy frontier with upgraded detectors that will address some of the biggest questions in particle physics.Until CERN's LHC switches on, the Tevatron proton-antiproton collider is the world's only source of top quarks. It is the only place where we can search for supersymmetry, for the Higgs boson, and for signatures of additional dimensions of space-time. The US Department of Energy (DOE) recently convened a high-level international review committee to examine Fermilab experts' first-phase plans for the accelerator complex. Pictured here with a dipole magnet in CERN's LHC magnet test facility are the four CERN scientists who took part in the DOE's Tevatron review. Left to right: Francesco Ruggiero, Massimo Placidi, Flemming Pedersen, and Karlheinz Schindl. Further information: CERN Courier 43 (1)

  9. Repository Planning, Design, and Engineering: Part II-Equipment and Costing.

    Science.gov (United States)

    Baird, Phillip M; Gunter, Elaine W

    2016-08-01

    Part II of this article discusses and provides guidance on the equipment and systems necessary to operate a repository. The various types of storage equipment and monitoring and support systems are presented in detail. While the material focuses on the large repository, the requirements for a small-scale startup are also presented. Cost estimates and a cost model for establishing a repository are presented. The cost model presents an expected range of acquisition costs for the large capital items in developing a repository. A range of 5,000-7,000 ft(2) constructed has been assumed, with 50 frozen storage units, to reflect a successful operation with growth potential. No design or engineering costs, permit or regulatory costs, or smaller items such as the computers, software, furniture, phones, and barcode readers required for operations have been included.

  10. Multiobjective Optimization for Fixture Locating Layout of Sheet Metal Part Using SVR and NSGA-II

    Directory of Open Access Journals (Sweden)

    Yuan Yang

    2017-01-01

    Full Text Available Fixture plays a significant role in determining the sheet metal part (SMP spatial position and restraining its excessive deformation in many manufacturing operations. However, it is still a difficult task to design and optimize SMP fixture locating layout at present because there exist multiple conflicting objectives and excessive computational cost of finite element analysis (FEA during the optimization process. To this end, a new multiobjective optimization method for SMP fixture locating layout is proposed in this paper based on the support vector regression (SVR surrogate model and the elitist nondominated sorting genetic algorithm (NSGA-II. By using ABAQUS™ Python script interface, a parametric FEA model is established. And the fixture locating layout is treated as design variables, while the overall deformation and maximum deformation of SMP under external forces are as the multiple objective functions. First, a limited number of training and testing samples are generated by combining Latin hypercube design (LHD with FEA. Second, two SVR prediction models corresponding to the multiple objectives are established by learning from the limited training samples and are integrated as the multiobjective optimization surrogate model. Third, NSGA-II is applied to determine the Pareto optimal solutions of SMP fixture locating layout. Finally, a multiobjective optimization for fixture locating layout of an aircraft fuselage skin case is conducted to illustrate and verify the proposed method.

  11. Factors influencing soft tissue profile changes following orthodontic treatment in patients with Class II Division 1 malocclusion

    Directory of Open Access Journals (Sweden)

    Suhatcha Maetevorakul

    2016-05-01

    Full Text Available Abstract Background Several studies have shown soft tissue profile changes after orthodontic treatment in Class II Division 1 patients. However, a few studies have described factors influencing the soft tissue changes. The purpose of this study was to investigate the factors influencing the soft tissue profile changes following orthodontic treatment in Class II Division 1 patients. Methods The subjects comprised 104 Thai patients age 8–16 years who presented Class II Division 1 malocclusions and were treated with different orthodontic modalities comprising cervical headgear, Class II traction and extraction of the four first premolars. The profile changes were evaluated from the lateral cephalograms before and after treatment by means of the X-Y coordinate system. Significant soft tissue profile changes were evaluated by paired t test at a 0.05 significance level. The correlations among significant soft tissue changes and independent variables comprising treatment modality, age, sex, pretreatment skeletal, dental and soft tissue morphology were evaluated by stepwise multiple regression analysis at a 0.05 significance level. Results The multiple regression analysis indicated that different treatment modalities, age, sex, pretreatment skeletal, dental and soft tissue morphology were related to the profile changes. The predictive power of these variables on the soft tissue profile changes ranged from 9.9 to 40.3 %. Conclusions Prediction of the soft tissue profile changes following treatment of Class II Division 1 malocclusion from initial patient morphology, age, sex and types of treatment was complicated and required several variables to explain their variations. Upper lip change in horizontal direction could be found only at the stomion superius and was less predictable than those of the lower lip. Variations in upper lip retraction at the stomion superius were explained by types of treatment (R 2 = 0.099, whereas protrusion of the lower

  12. Factors influencing soft tissue profile changes following orthodontic treatment in patients with Class II Division 1 malocclusion.

    Science.gov (United States)

    Maetevorakul, Suhatcha; Viteporn, Smorntree

    2016-01-01

    Several studies have shown soft tissue profile changes after orthodontic treatment in Class II Division 1 patients. However, a few studies have described factors influencing the soft tissue changes. The purpose of this study was to investigate the factors influencing the soft tissue profile changes following orthodontic treatment in Class II Division 1 patients. The subjects comprised 104 Thai patients age 8-16 years who presented Class II Division 1 malocclusions and were treated with different orthodontic modalities comprising cervical headgear, Class II traction and extraction of the four first premolars. The profile changes were evaluated from the lateral cephalograms before and after treatment by means of the X-Y coordinate system. Significant soft tissue profile changes were evaluated by paired t test at a 0.05 significance level. The correlations among significant soft tissue changes and independent variables comprising treatment modality, age, sex, pretreatment skeletal, dental and soft tissue morphology were evaluated by stepwise multiple regression analysis at a 0.05 significance level. The multiple regression analysis indicated that different treatment modalities, age, sex, pretreatment skeletal, dental and soft tissue morphology were related to the profile changes. The predictive power of these variables on the soft tissue profile changes ranged from 9.9 to 40.3%. Prediction of the soft tissue profile changes following treatment of Class II Division 1 malocclusion from initial patient morphology, age, sex and types of treatment was complicated and required several variables to explain their variations. Upper lip change in horizontal direction could be found only at the stomion superius and was less predictable than those of the lower lip. Variations in upper lip retraction at the stomion superius were explained by types of treatment (R(2) = 0.099), whereas protrusion of the lower lip at the labrale inferius was correlated with initial inclination of

  13. Psychoeducational Interventions with Pediatric Cancer Patients: Part II. Effects of Information and Skills Training on Health-Related Outcomes

    Science.gov (United States)

    Beale, Ivan L.; Bradlyn, Andrew S.; Kato, Pamela M.

    2003-01-01

    In Part I of this paper, we described a model that was used as a framework for reviewing studies of psychoeducational interventions intended to influence illness- and treatment-related behaviors and attitudes in pediatric cancer patients. In Part II, we distinguish between interventions that attempt to influence patients' behaviors just by…

  14. The Mental Health Recovery Movement and Family Therapy, Part II: A Collaborative, Appreciative Approach for Supporting Mental Health Recovery

    Science.gov (United States)

    Gehart, Diane R.

    2012-01-01

    A continuation of Part I, which introduced mental health recovery concepts to family therapists, Part II of this article outlines a collaborative, appreciative approach for working in recovery-oriented contexts. This approach draws primarily upon postmodern therapies, which have numerous social justice and strength-based practices that are easily…

  15. Sexuality and Personal Relationships for People with an Intellectual Disability. Part II: Staff and Family Carer Perspectives

    Science.gov (United States)

    Evans, D. S.; McGuire, B. E.; Healy, E.; Carley, S. N.

    2009-01-01

    Background: Recent ideological shifts in service provision promote appropriate sexual expression for people with an intellectual disability (ID), although there is little evidence that such advances in ideology are matched by current service provision. Part II of the current two-part study assessed the attitudes of staff and family carers to the…

  16. Inspection of the lids of shallowly buried concrete structures based on the propagation of surface waves- PART II

    Science.gov (United States)

    Tremblay, Simon-Pierre; Karray, Mourad; Chekired, Mohamed; Bessette, Carole; Jinga, Livius

    2018-01-01

    The possibility of performing the inspection of an underground structure directly from the surface of the soil would be advantageous for the inspection of various type of underground utility structures present in modern cities. In part I, the behavior of elastic waves propagating in a soil profile containing a shallowly buried underground concrete utility structure was studied and it was found that it is possible to evaluate the condition of the surface of the lid of such structures based on the propagation velocity of elastic waves. The part II follows from the work that was previously performed to develop a nondestructive technique for the inspection of shallowly buried utility structures based on the propagation of elastic waves. First, the three-dimensional finite difference method implemented in the software Fast Lagrangian Analysis of Continuum was used to model an underground concrete structure to show how the presence of a manhole and of a pavement at the surface of the soil affect the propagation of elastic waves. Second, a receiver configuration typically used in three-dimensional seismic surveys is presented and its effectiveness is tested on three different existing underground structures. The signals collected during the field tests are analyzed independently in the velocity-frequency plane using an adaptive signal processing technique. The velocity-frequency representation of each signal is then used to identify the different elastic waves and to calculate their group velocities. Third, the variation of the group velocity at the surface of the three concrete structures is presented in the form of two-dimensional contour maps that enabled the detection of anomalies on the surface of two of these structures. Finally, it is shown how the collected data can be used to obtain a three-dimensional tomography representative of the condition of the surface of an underground structure.

  17. Wind Profiles and Wave Spectra for Potential Wind Farms in South China Sea. Part I: Wind Speed Profile Model

    Directory of Open Access Journals (Sweden)

    Yichao Liu

    2017-01-01

    Full Text Available With the setting of wind energy harvesting moving from coastal waters to deep waters, the South China Sea has been deemed to offer great potential for the construction of floating wind farms thanks to the abundance of wind energy resources. An engineering model describing the wind profiles and wave spectra specific to the South China Sea conditions, which is the precondition for offshore wind farm construction, has, however, not yet been proposed. In the present study, a series of numerical simulations have been conducted using the Weather Forecast and Research model. Through analyzing the wind and wave information extracted from the numerical simulation results, engineering models to calculate vertical profiles of wind speeds and wave spectra have been postulated. While the present paper focuses on the wind profile model, a companion paper articulates the wave spectrum model. For wind profiles under typhoon conditions, the power-law and log-law models have been found applicable under the condition that the Hellmann exponent α or the friction velocity u * are modified to vary with the wind strength. For wind profiles under non-typhoon conditions, the log-law model is revised to take into consideration the influence of the atmospheric stability.

  18. Reciprocity-enhanced optical communication through atmospheric turbulence - part II: communication architectures and performance

    Science.gov (United States)

    Puryear, Andrew L.; Shapiro, Jeffrey H.; Parenti, Ronald R.

    2012-10-01

    Free-space optical communication provides rapidly deployable, dynamic communication links that are capable of very high data rates compared with those of radio-frequency systems. As such, free-space optical communication is ideal for mobile platforms, for platforms that require the additional security afforded by the narrow divergence of a laser beam, and for systems that must be deployed in a relatively short time frame. In clear-weather conditions the data rate and utility of free-space optical communication links are primarily limited by fading caused by micro-scale atmospheric temperature variations that create parts-per-million refractive-index fluctuations known as atmospheric turbulence. Typical communication techniques to overcome turbulence-induced fading, such as interleavers with sophisticated codes, lose viability as the data rate is driven higher or the delay requirement is driven lower. This paper, along with its companion [J. H. Shapiro and A. Puryear, "Reciprocity-Enhanced Optical Communication through Atmospheric Turbulence-Part I: Reciprocity Proofs and Far-Field Power Transfer"], present communication systems and techniques that exploit atmospheric reciprocity to overcome turbulence which are viable for high data rate and low delay requirement systems. Part I proves that reciprocity is exhibited under rather general conditions, and derives the optimal power-transfer phase compensation for far-field operation. The Part II paper presents capacity-achieving architectures that exploit reciprocity to overcome the complexity and delay issues that limit state-of-the art free-space optical communications. Further, this paper uses theoretical turbulence models to determine the performance—delay, throughput, and complexity—of the proposed architectures.

  19. Profile and severity of the patients of intensive care units: prospective application of the APACHE II index.

    Science.gov (United States)

    De Freitas, Eliane Regina Ferreira Sernache

    2010-01-01

    This study aimed to understand the profile and severity of patients in physiotherapy treatment after their admission to the intensive care unit (ICU) by applying the APACHE II index. One hundred and forty six subjects, with a mean age of 60.5 +/- 19.2 years, were evaluated. The APACHE II index was applied in the first 24 hours to evaluate the severity and mortality risk score. Patients were monitored until hospital discharge or death. The mean APACHE II score was 20+/-7.3 with an estimated risk of death of 32.4% and observed mortality of 58.2%. The mean hospital stay was 27.8+/-25.2 days. The patients in physiotherapy at the institution studied were predominantly male, elderly, from the emergency service for treatment (non-surgical), and had clear severity, suggested by the APACHE II score and the observed mortality.

  20. Advances in Knowledge Discovery and Data Mining 21st Pacific Asia Conference, PAKDD 2017 Held in Jeju, South Korea, May 23 26, 2017. Proceedings Part I, Part II.

    Science.gov (United States)

    2017-06-27

    currently val!d OMB control number. PLEASE DD NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE (DD-MM-YYYY) 2. REPORT TYPE 3. DATES COVERED...Data Mining 21’’ Pacific-Asia Conference, PAKDD 2017Jeju, South Korea, May 23-26, Sb. GRANT NUMBER 2017 Proceedings, Part I, Part II Sc. PROGRAM...Springer; Switzerland. 14. ABSTRACT The Pacific-Asia Conference on Knowledge Discovery and Data Mining (PAKDD) is a leading international conference

  1. [Education in our time: competency or aptitude? The case for medicine. Part II].

    Science.gov (United States)

    Viniegra-Velázquez, Leonardo

    Part II is focused on participatory education (PE), a distinctive way to understand and practice education in contrast to passive education. The core of PE is to develop everyone's own cognitive potentialities frequently mutilated, neglected or ignored. Epistemological and experiential basis of PE are defined: the concept of incisive and creative criticism, the idea of knowledge as each person's own construct and life experience as the main focus of reflection and cognition. The PE aims towards individuals with unprecedented cognitive and creative faculties, capable of approaching a more inclusive and hospitable world. The last part criticizes the fact that medical education has remained among the passive education paradigm. The key role of cognitive aptitudes, both methodological and practical (clinical aptitude), in the progress of medical education and practice is emphasized. As a conclusion, the knowhow of education is discussed, aiming towards a better world away from human and planetary degradation. Copyright © 2017 Hospital Infantil de México Federico Gómez. Publicado por Masson Doyma México S.A. All rights reserved.

  2. Interview-Based Qualitative Research in Emergency Care Part II: Data Collection, Analysis and Results Reporting

    Science.gov (United States)

    Ranney, Megan L.; Meisel, Zachary; Choo, Esther K.; Garro, Aris; Sasson, Comilla; Morrow, Kathleen

    2015-01-01

    Qualitative methods are increasingly being used in emergency care research. Rigorous qualitative methods can play a critical role in advancing the emergency care research agenda by allowing investigators to generate hypotheses, gain an in-depth understanding of health problems or specific populations, create expert consensus, and develop new intervention and dissemination strategies. In Part I of this two-article series, we provided an introduction to general principles of applied qualitative health research and examples of its common use in emergency care research, describing study designs and data collection methods most relevant to our field (observation, individual interviews, and focus groups). Here in Part II of this series, we outline the specific steps necessary to conduct a valid and reliable qualitative research project, with a focus on interview-based studies. These elements include building the research team, preparing data collection guides, defining and obtaining an adequate sample, collecting and organizing qualitative data, and coding and analyzing the data. We also discuss potential ethical considerations unique to qualitative research as it relates to emergency care research. PMID:26284572

  3. Fall prevention in frail elderly nursing home residents: a challenge to case management: part II.

    Science.gov (United States)

    Theodos, Phyllis

    2004-01-01

    Parts I and II of this article examine the impact of a falls prevention program on the fall incidents among the residents in a nursing home. It was hypothesized that a diagnostic, therapeutic, and preventive approach should be used for nursing home residents identified as being at high risk for falls in order to reduce the number of fall incidents and to improve quality of life for this vulnerable population. The program effectively targeted both intrinsic and extrinsic factors to reduce risks facing the residents. The effectiveness of the program was evaluated by examining changes in the rate of falls after the program was implemented. The results identified that a multifaceted program, one that utilized multiple personalized interventions, was effective in reducing the falls rate of frail (those with complex medical and psychosocial problems) nursing home residents, and that muscle-strengthening interventions may be beneficial for this vulnerable population. Program outcomes verified that case managers can impact quality of life for frail elderly nursing home residents by promoting their independence and safety, and postponing problems resulting from inactivity. Part I (LCM, Nov-Dec 2001) discussed the background and process of a falls program and factors contributing to the occurrence of falls. This month we examine the interdisciplinary team approach to assessment, method, and implementing strategies for an effective fall prevention program. Tools used for prevention, monitoring, and investigation of falls are also detailed.

  4. Long-term solar activity and terrestrial connections. Part II: at the beckon of the sun?

    Directory of Open Access Journals (Sweden)

    N. D. Diamantides

    1998-05-01

    Full Text Available The research task described herein aims at the structuring of an analytical tool that traces the time course of geophysical phenomena, regional or global, and compares it to the course of long-term solar conditions, long-term meaning decades or a few centuries. The model is based on the premise that since in a last analysis the preponderance of atmospheric, hydrospheric, and, possibly, some aspects of geospheric phenomena are, or have been, powered by energy issuing from the sun - either now or in the past - the long-term behavior of such phenomena is ultimately "connected" to long-term changes occurring in the sun itself. Accordingly, the proposed research firstly derives and models a stable surrogate pattern for the long-term solar activity, secondly introduces a transfer-function algorithm for modeling the connection between the surrogate and terrestrial phenomena viewed as partners in the connection, and thirdly probes the connection outcome for episodic or unanticipated effects that may arise due to the fact that in the present context, the connection, should it exist, is very likely nonlinear. Part I of the study presents the theory of the concept, while Part II demonstrates the concept's pertinence to a number of terrestrial phenomena.Key words. Solar activity · Kolmogorov algorithm

  5. Pharmacokinetics, Pharmacodynamics, and Pharmacogenomics of Immunosuppressants in Allogeneic Hematopoietic Cell Transplantation: Part II.

    Science.gov (United States)

    McCune, Jeannine S; Bemer, Meagan J; Long-Boyle, Janel

    2016-05-01

    Part I of this article included a pertinent review of allogeneic hematopoietic cell transplantation (alloHCT), the role of postgraft immunosuppression in alloHCT, and the pharmacokinetics, pharmacodynamics, and pharmacogenomics of the calcineurin inhibitors and methotrexate. In this article (Part II), we review the pharmacokinetics, pharmacodynamics, and pharmacogenomics of mycophenolic acid (MPA), sirolimus, and the antithymocyte globulins (ATG). We then discuss target concentration intervention (TCI) of these postgraft immunosuppressants in alloHCT patients, with a focus on current evidence for TCI and on how TCI may improve clinical management in these patients. Currently, TCI using trough concentrations is conducted for sirolimus in alloHCT patients. Several studies demonstrate that MPA plasma exposure is associated with clinical outcomes, with an increasing number of alloHCT patients needing TCI of MPA. Compared with MPA, there are fewer pharmacokinetic/dynamic studies of rabbit ATG and horse ATG in alloHCT patients. Future pharmacokinetic/dynamic research of postgraft immunosuppressants should include '-omics'-based tools: pharmacogenomics may be used to gain an improved understanding of the covariates influencing pharmacokinetics as well as proteomics and metabolomics as novel methods to elucidate pharmacodynamic responses.

  6. Interview-based Qualitative Research in Emergency Care Part II: Data Collection, Analysis and Results Reporting.

    Science.gov (United States)

    Ranney, Megan L; Meisel, Zachary F; Choo, Esther K; Garro, Aris C; Sasson, Comilla; Morrow Guthrie, Kate

    2015-09-01

    Qualitative methods are increasingly being used in emergency care research. Rigorous qualitative methods can play a critical role in advancing the emergency care research agenda by allowing investigators to generate hypotheses, gain an in-depth understanding of health problems or specific populations, create expert consensus, and develop new intervention and dissemination strategies. In Part I of this two-article series, we provided an introduction to general principles of applied qualitative health research and examples of its common use in emergency care research, describing study designs and data collection methods most relevant to our field (observation, individual interviews, and focus groups). Here in Part II of this series, we outline the specific steps necessary to conduct a valid and reliable qualitative research project, with a focus on interview-based studies. These elements include building the research team, preparing data collection guides, defining and obtaining an adequate sample, collecting and organizing qualitative data, and coding and analyzing the data. We also discuss potential ethical considerations unique to qualitative research as it relates to emergency care research. © 2015 by the Society for Academic Emergency Medicine.

  7. Diagnosing DSM-IV--Part II: Eysenck (1986) and the essentialist fallacy.

    Science.gov (United States)

    Wakefield, J C

    1997-07-01

    In Part I (Wakefield, 1997, Behaviour Research and Therapy, 35, 633-649) of this two-article series, I used the harmful dysfunction analysis of the concept of disorder (Wakefield, 1992a, American Psychologist, 47, 373-388) to 'diagnose' a problem with DSM-IV. I argued that DSM-IV diagnostic criteria often violate the 'dysfunction' requirement by invalidity classifying harms not caused by dysfunctions as disorders. In Part II, I examine Eysenck's (Eysenck, 1986, Contemporary directions in psychopathology: Toward the DSM-IV) argument that DSM commits a 'categorical fallacy' and should be replaced by dimensional diagnoses based on Eysenckian personality traits. I argue that Eysenck's proposed diagnostic criteria violate the 'harm' requirement by invalidly classifying symptomless conditions as disorders. Eysenck commits an 'essentialist fallacy'; he misconstrues 'disorder' as an essentialist theoretical concept when in fact it is a hybrid theoretical-practical or 'cause-effect' concept. He thus ignores the harmful effects essential to disorder that are captured in DSM's symptom-based categories.

  8. A novel embeddable spherical smart aggregate for structural health monitoring: part II. Numerical and experimental verifications

    Science.gov (United States)

    Kong, Qingzhao; Fan, Shuli; Mo, Y. L.; Song, Gangbing

    2017-09-01

    The newly developed spherical smart aggregate (SSA) based on a radially polarized spherical piezoceramic shell element has unique omnidirectional actuating and sensing capabilities that can greatly improve the detection aperture and provide additional functionalities in health monitoring applications in concrete structures. Detailed fabrication procedures and electrical characterization of the SSA have been previously studied (Part I). In this second paper (Part II), the functionalities of the SSA used in both active sensing and passive sensing approaches were investigated in experiments and numerical simulations. One SSA sample was embedded in a 1 ft3 concrete specimen. In the active sensing approach, the SSA was first utilized as an actuator to generate stress waves and six conventional smart aggregates (SA) mounted on the six faces of the concrete cube were utilized as sensors to detect the wave response. Conversely, the embedded SSA was then utilized as a sensor to successively detect the wave response from each SA. The experimentally obtained behavior of the SSA was then compared with the numerical simulation results. Further, a series of impact tests were conducted to verify the performance of the SSA in the detection of the impact events from different directions. Comparison with the wave response associated with different faces of the cube verified the omnidirectional actuating and sensing capabilities of the SSA.

  9. Differentially Encoded LDPC Codes—Part II: General Case and Code Optimization

    Directory of Open Access Journals (Sweden)

    Li (Tiffany Jing

    2008-01-01

    Full Text Available This two-part series of papers studies the theory and practice of differentially encoded low-density parity-check (DE-LDPC codes, especially in the context of noncoherent detection. Part I showed that a special class of DE-LDPC codes, product accumulate codes, perform very well with both coherent and noncoherent detections. The analysis here reveals that a conventional LDPC code, however, is not fitful for differential coding and does not, in general, deliver a desirable performance when detected noncoherently. Through extrinsic information transfer (EXIT analysis and a modified "convergence-constraint" density evolution (DE method developed here, we provide a characterization of the type of LDPC degree profiles that work in harmony with differential detection (or a recursive inner code in general, and demonstrate how to optimize these LDPC codes. The convergence-constraint method provides a useful extension to the conventional "threshold-constraint" method, and can match an outer LDPC code to any given inner code with the imperfectness of the inner decoder taken into consideration.

  10. Rare or remarkable microfungi from Oaxaca (south Mexico)--Part II.

    Science.gov (United States)

    Ale-Agha, N; Jensen, M; Brassmann, M; Kautz, S; Eilmus, S; Ballhorn, D J

    2008-01-01

    Microfungi were collected in southern Mexico in the vicinity of Puerto Escondido, Oaxaca in 2007. In 2006, samples were gathered from Acacia myrmecophytes [(Remarkable microfungi from Oaxaca of Acacia species) Part I]. In the present investigation [Part II], we collected microfungi from different parts of a variety of wild and cultivated higher plants belonging to the families Anacardiaceae, Caricaceae, Fabaceae, Moraceae, and Nyctaginacae. The microfungi found here live as parasites or saprophytes. Interestingly, the species Colletotrichum lindemuthianum (Sacc. and Magn.) Briosi and Cavara has repeatedly been used to cause fungal infections of Phaseolus lunatus leaves in laboratory experiments. We could now find the same fungus as parasite on the same host plants under field conditions showing that results obtained in the laboratory are also relevant in nature. Most of the fungal species collected belong to the classes Ascomycotina, Basidiomycotina and Deuteromycotina. Until now, some of the microfungi identified in this study have been rarely observed before or have been reported for the first time in Mexico, for example: Pestalotia acaciae Thüm. on Acacia collinsii Safford; Corynespora cassiicola (Berk. and M.A. Curtis) C.T. Wei on Carica papaya L.; Botryosphaeria ribis Grossenb. and Duggar and Cercosporella leucaenae (Raghu Ram and Mallaiah) U. Braun (new for Mexico) and Camptomeris leucaenae (F. Stevens and Dalbey) Syd. (new for Mexico) on Leucaena leucocephala (Lam.) de Wit.; Oidium clitoriae Narayanas. and K. Ramakr. and Phakopsora cf. pachyrhizi Sydow and Sydow (new for Mexico) on Clitoria ternatea L.; Botryosphaeria obtusa (Schw.) Shoemaker on Prosopis juliflora (Sw.) DC.; Cylindrocladium scoparium Morg. on Ficus benjamina L.; Acremonium sp. on Bougainvillea sp. All specimens are located in the herbarium ESS. Mycotheca Parva collection G.B. Feige and N. Ale-Agha.

  11. Gunshot residue testing in suicides: Part II: Analysis by inductive coupled plasma-atomic emission spectrometry.

    Science.gov (United States)

    Molina, D Kimberley; Castorena, Joe L; Martinez, Michael; Garcia, James; DiMaio, Vincent J M

    2007-09-01

    Several different methods can be employed to test for gunshot residue (GSR) on a decedent's hands, including scanning electron microscopy with energy dispersive x-ray (SEM/EDX) and inductive coupled plasma-atomic emission spectrometry (ICP-AES). In part I of this 2-part series, GSR results performed by SEM/EDX in undisputed cases of suicidal handgun wounds were studied. In part II, the same population was studied, deceased persons with undisputed suicidal handgun wounds, but GSR testing was performed using ICP-AES. A total of 102 cases were studied and analyzed for caliber of weapon, proximity of wound, and the results of the GSR testing. This study found that 50% of cases where the deceased was known to have fired a handgun immediately prior to death had positive GSR results by ICP/AES, which did not differ from the results of GSR testing by SEM/EDX. Since only 50% of cases where the person is known to have fired a weapon were positive for GSR by either method, this test should not be relied upon to determine whether someone has discharged a firearm and is not useful as a determining factor of whether or not a wound is self-inflicted or non-self-inflicted. While a positive GSR result may be of use, a negative result is not helpful in the medical examiner setting as a negative result indicates that either a person fired a weapon prior to death or a person did not fire a weapon prior to death.

  12. On the Processing of Spalling Experiments. Part II: Identification of Concrete Fracture Energy in Dynamic Tension

    Science.gov (United States)

    Lukić, Bratislav B.; Saletti, Dominique; Forquin, Pascal

    2017-12-01

    This paper presents a second part of the study aimed at investigating the fracture behavior of concrete under high strain rate tensile loading. The experimental method together with the identified stress-strain response of three tests conducted on ordinary concrete have been presented in the paper entitled Part I (Forquin and Lukić in Journal of Dynamic Behavior of Materials, 2017. https://doi.org/10.1007/s40870-017-0135-1). In the present paper, Part II, the investigation is extended towards directly determining the specific fracture energy of each observed fracture zone by visualizing the dynamic cracking process with a temporal resolution of 1 µs. Having access to temporal displacement fields of the sample surface, it is possible to identify the fracture opening displacement (FOD) and the fracture opening velocity of any principle (open) and secondary (closed) fracture at each measurement instance, that may or may not lead to complete physical failure of the sample. Finally, the local Stress-FOD curves were obtained for each observed fracture zone, opposed to previous works where indirect measurements were used. The obtained results indicated a much lower specific fracture energy compared to the results often found in the literature. Furthermore, numerical simulations were performed with a damage law to evaluate the validity of the proposed experimental data processing and compare it to the most often used one in the previous works. The results showed that the present method can reliably predict the specific fracture energy needed to open one macro-fracture and suggested that indirect measurement techniques can lead to an overestimate of specific fracture energy due to the stringent assumption of linear elasticity up-to the peak and the inability of having access to the real post-peak change of axial stress.

  13. Viabilidade do emprego de cinza de casca de arroz natural em concreto estrutural (parte II: durabilidade

    Directory of Open Access Journals (Sweden)

    Geraldo Cechella Isaia

    Full Text Available Resumo Os resíduos incorporados aos materiais de construção devem ser usados, se possível, sem processamentos, para evitar o aumento dos impactos ambientais e custos adicionais. A cinza de casca de arroz (CCA é uma pozolana que deve ser previamente moída, para aumentar a finura e a reatividade com o cimento, quando empregada como material cimentício. Este trabalho estuda cinza de casca de arroz natural (CCAN sem processamento em substituição parcial de 15% de cimento, em massa, para uso em concreto estrutural, cominuída por moagem conjunta com os agregados no tambor da betoneira. Na parte I desta pesquisa, já publicada, são apresentados os resultados de microestrutura, resistência mecânica e retração, também para o teor de 25%, e nesta parte II são mostrados os dados dos ensaios de durabilidade (carbonatação, penetração de cloretos, resistividade, absorção d'água, permeabilidade ao oxigênio, absorção capilar e reação álcali-sílica - RAS, comparados ao concreto referência com 100% de cimento e, ainda, com CCA moída previamente (CCAM. Os resultados mostram que 15% de CCAN é factível de ser empregado em concreto porque apresenta desempenho superior ao concreto referência, quando usado cimento com pozolanas e próximos ou até superiores às misturas de CCAM, para grande parte das variáveis estudadas. Conclui-se que 15% de CCAN para concreto estrutural é viável e traz maior sustentabilidade.

  14. Transmission of vertical stress in a real soil profile. Part II

    DEFF Research Database (Denmark)

    Lamandé, Mathieu; Schjønning, Per

    2011-01-01

    We urgently need increased quantitative knowledge about stress transmission in real soils that suffer heavy loads of agricultural machinery. 3D measurements of vertical stresses under tracked wheels were performed in situ in an annually ploughed Stagnic Luvisol continuously cropped with small grain...... used rated tyre inflation pressures for traffic in the field (≤10 km h−1 driving speed). Seven load cells were inserted horizontally from a pit with minimal disturbance of soil at each of three depths (0.3, 0.6 and 0.9 m), covering the width of the wheeled area. The position of the wheel relative...... ground pressure and the tyre inflation pressure. The maximum stresses measured at 0.9 m depth were correlated with the wheel load (57 and 60 kPa at 60 kN load; 27 and 25 kPa at 30 kN load) and did not reflect the surface-related stress expressions. Our results show that the use of wide, low pressure...

  15. Sludge in the pulp and paper industry in Sweden, part II[Combustion of]; Slam fraan skogsindustrin, fas II

    Energy Technology Data Exchange (ETDEWEB)

    Gyllenhammar, Marianne; Herstad Svaerd, Solvie; Kjoerk, Anders; Larsson, Sara; Wennberg, Olle [S.E.P. Scandinavian Energy Project AB, Goeteborg (Sweden); Aamand, Lars-Erik [Chalmers Univ. of Technology, Goeteborg (Sweden); Eskilsson, David [Swedish National Testing and Research Inst., Boraas (Sweden)

    2003-11-01

    During part II of this research program combustible sludge from the pulp and paper industry has been studied in detail. 560,000 tonnes of sludge per year (calculated as dry sludge) are produced in Sweden. The energy potential in the produced sludge is about 2 TWh/year. Today 1 TWh/year is produced in the pulp and paper mill's own boilers. This means that additional energy can be utilized from this material. An objective of this program has been to decide whether or not there are sludge types which are favourable respectively difficult to combust. By mixing different sludge types, or other waste products, emissions and/or problems during combustion can be minimized. These possibilities have been studied thoroughly in this program. A lot of sludge samples have been studied in laboratory scale at SP and in full-scale at Chalmers 12 MW CFB boiler. As a complement to the practical tests S.E.P. has done research regarding different aspects of sludge as a fuel; for example handling of sludge and regional drying. The results of 40 sintering tests at SP showed that the sintering temperature during combustion of sludge in a fluidised bed, with silica sand as bed material, varied between <850 deg C and >1100 deg C. The evaluation showed that the alkali content in the ash had the largest influence on the sintering temperature. Other factors were less important. During the tests at Chalmers eleven different sludge samples have been combusted together with wood pellets. Initially there were problems with the feeding to the boiler for some of the sludge samples. When the fuel feeding problems were solved the combustion took place without any problems. When sludge is co-combusted together with a 'clean' base fuel such as wood pellets the sulphur-, nitrogen- and chloride contents in the sludge have a large impact on the emissions. The normal way to reduce sulphur dioxide but also hydrogen chloride is to add lime in different positions into and after the boiler. In

  16. Hydration profile and sweat loss perception of male and female division II basketball players during practice.

    Science.gov (United States)

    Thigpen, Lauren K; Green, James M; OʼNeal, Eric K

    2014-12-01

    Hydration affects multiple aspects of basketball performance, but few investigations have examined the hydration profiles of collegiate basketball players. We examined multiday prepractice hydration status of 11 male and 11 female NCAA (National Collegiate Athletic Association) Division II basketball players' sweat losses, fluid intake, and how accurately players estimated their sweat losses. Urine-specific gravity (USG) was spontaneously assessed before 2 practices. Sweat losses and fluid intakes were measured during a conditioning practice (CP) and sport-specific practice (SP). After practices, players filled 1,030 ml practice bottles to estimate their sweat losses. Urine-specific gravity between practices exhibited a moderate correlation (r = 0.54; p = 0.012) and were consistently high (17% of samples = USG >1.030) with no difference in mean USG between men (1.026 ± 0.004) and women (1.022 ± 0.008). Athletes' estimations of their sweat loss volumes between CP and the longer SP were strongly correlated (r = 0.88; p < 0.001). Estimation error was high (absolute error for both practices = 71 ± 52%) and error direction varied greatly within men. Women consistently underestimated sweat losses by 63 ± 28% and 65 ± 20% during CP and SP. Sweat losses during SP equaled 2,471 ± 495 ml and 1,910 ± 441 ml for men and women, respectively, but high practice fluid intake limited body mass losses to 1.1 ± 0.6% by the end of practice. It is plausible that hypohydration is related to poor conceptualization of sweat losses. Simulating the methodology of this study could help identify chronically hypohydrated athletes and be used to educate on between-practice fluid needs.

  17. Children's exposure to indoor air in urban nurseries--Part II: Gaseous pollutants' assessment.

    Science.gov (United States)

    Branco, P T B S; Nunes, R A O; Alvim-Ferraz, M C M; Martins, F G; Sousa, S I V

    2015-10-01

    This study, Part II of the larger study "Children's exposure to indoor air in urban nurseries", aimed to: (i) evaluate nursery schools' indoor concentrations of several air pollutants in class and lunch rooms; and (ii) analyse them according to guidelines and references. Indoor continuous measurements were performed, and outdoor concentrations were obtained to determine indoor/outdoor ratios. The influence of outdoor air seemed to be determinant on carbon monoxide (CO), nitrogen dioxide (NO2) and ozone (O3) indoor concentrations. The peak concentrations of formaldehyde and volatile organic compounds (VOC) registered (highest concentrations of 204 and 2320 µg m(-3) respectively), indicated the presence of specific indoor sources of these pollutants, namely materials emitting formaldehyde and products emitting VOC associated to cleaning and children's specific activities (like paints and glues). For formaldehyde, baseline constant concentrations along the day were also found in some of the studied rooms, which enhances the importance of detailing the study of children's short and long-term exposure to this indoor air pollutant. While CO, NO2 and O3 never exceeded the national and international reference values for IAQ and health protection, exceedances were found for formaldehyde and VOC. For this reason, a health risk assessment approach could be interesting for future research to assess children's health risks of exposure to formaldehyde and to VOC concentrations in nursery schools. Changing cleaning schedules and materials emitting formaldehyde, and more efficient ventilation while using products emitting VOC, with the correct amount and distribution of fresh air, would decrease children's exposure. Copyright © 2015 Elsevier Inc. All rights reserved.

  18. Measuring health-promoting behaviors: cross-cultural validation of the Health-Promoting Lifestyle Profile-II.

    Science.gov (United States)

    Sousa, Pedro; Gaspar, Pedro; Vaz, Daniela C; Gonzaga, Sílvia; Dixe, M Anjos

    2015-04-01

    Individual lifestyles have emerged as valuable health constructs. This study aims to psychometrically test the Portuguese (European) version of the Health-Promoting Lifestyle Profile-II. After an adequate linguistic and cultural adaptation of the Health-Promoting Lifestyle Profile-II scale, their psychometric properties were assessed (N = 889) by Cronbach's alpha and confirmatory factor analysis. Results showed an adequate fit to a 52-item, six-factor structure. A global alpha of .925 was obtained. The Portuguese version demonstrated good validity and reliability in a wide adult sample, and can thus be applied to the Portuguese population. This instrument is useful as an evaluation tool for health-promoting lifestyles and as an instrument for testing the effectiveness of health-promoting programs. © 2014 NANDA International, Inc.

  19. Manufacturing processes of cellular metals. Part II. Solid route, metals deposition, other processes; Procesos de fabricacion de metales celulares. Parte II: Via solida, deposicion de metales otros procesos

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez, P.; Cruz, L. J.; Coleto, J.

    2009-07-01

    At the first part of this paper review a description about cellular metal processes by liquid route, was made. In this second part, solid processes and metals deposition are described. In similar way, the different kind of processes in each case are reviewed; making a short description about the main parameters involved and the advantages and drawbacks in each of them. (Author) 147 refs.

  20. Volatile oil profiles of the aerial parts of Jordanian garland, Chrysanthemum coronarium.

    Science.gov (United States)

    Tawaha, K; Hudaib, M

    2010-10-01

    The study evaluates, qualitatively and quantitatively, the volatile oil profiles of the aerial parts of Jordanian garland Chrysanthemum coronarium L. (Asteraceae) and compares the findings with literature reports of garland of other sources, in terms of general composition and content of potentially active components. The chemical composition of the essential oils isolated by hydrodistillation from dried material composed of flowerheads (FH) and aerial parts except for flowerheads (AEF) was assessed by GC-FID and GC-MS. More than 60 components were identified in the studied oils, corresponding to about 99.6 and 99.7% of total oil constituents of FH and AEF, respectively. The oil was characterized by substantial levels of monoterpenes (76.9% in FH and 61.9% in AEF) and moderate levels of sesquiterpenes (15.7% in FH and 27.7% in AEF). The oil from FH was characterized by high levels of oxygenated monoterpenes (64.3%, compared to 15.3% in AEF) and moderate levels of both monoterpene-hydrocarbons (12.6%, compared to 46.6% in AEF as the major fraction) and sesquiterpene-hydrocarbons (14.7%, compared to 23.5% in AEF), while very low levels of oxygenated sesquiterpenes were observed in both oils (1.0% in FH and 4.2% in AEF). The principal oil component was camphor (17.5%) in FH and myrcene (36.7%) in AEF. Other major components identified in the FH oil were santolina triene (4.3%), neoiso-3-thujanol (5.6%), cis-chrysanthenyl acetate (10.8%), perilla aldehyde (11.7%), iso-italicene (4.7%), phenylpropyl butanoate (4.9%), and germacrene D (4.3%), while Z-β-ocimene (5.2%), isobornyl acetate (5.2%), E-β-farnesene (12.1%), and germacrene D (4.5%) were the major constituents of AEF oil.

  1. Neutronics and thermohydraulics of the reactor C.E.N.E. Part II; Analisis neutronico y termohidraulico del reactor C.E.N.E. Parte II

    Energy Technology Data Exchange (ETDEWEB)

    Caro, R.

    1976-07-01

    In this report the analysis of neutronics thermohydraulics and shielding of the 10 HWt swimming pool reactor C.E.N.E is included. In each of these chapters is given a short description of the theoretical model used, along with the theoretical versus experimental checking carried out, whenever possible, with the reactors JEN-I and JEN-II of Junta de Energia Nuclear. (Author) 11 refs.

  2. Comparative pharmacokinetic profiles of picrosides I and II from kutkin, Picrorhiza kurroa extract and its formulation in rats.

    Science.gov (United States)

    Upadhyay, Dilawar; Dash, Ranjeet Prasad; Anandjiwala, Sheetal; Nivsarkar, Manish

    2013-03-01

    Picrosides I and II are the active chemical constituents, present in the roots and rhizomes of Picrorhiza kurroa Royle (family: Scrophulariaceae). The plant is ethnomedically claimed for the treatment of liver and upper respiratory tract infection, fever, dyspepsia and scorpion sting. This study attempts to determine the in vivo pharmacokinetic profile of picrosides I and II in rats after oral administration of three different preparations namely, kutkin (a mixture of picrosides I and II), P. kurroa extract and Picrolax® capsule (marketed formulation). A simple, precise, specific and sensitive method was developed for simultaneous quantification of picrosides I and II in rat plasma and was applied for the pharmacokinetic study. Pharmacokinetic parameters were calculated from the observed plasma concentration of picrosides I and II. The results showed a significant difference (p≤0.05) in oral bioavailability of picrosides I and II from different preparations. Both the compounds were found to be more bioavailable from P. kurroa extract followed by Picrolax® capsule and kutkin. Moreover, we also developed a novel method for isolation of kutkin from roots of P. kurroa with a high yield of 2.4% w/w. The information gained from this study provides a meaningful basis for clinical application and mechanistic study of such phytochemicals. Copyright © 2013 Elsevier B.V. All rights reserved.

  3. Niacin Alternatives for Dyslipidemia: Fool's Gold or Gold Mine? Part II: Novel Niacin Mimetics.

    Science.gov (United States)

    Goel, Harsh; Dunbar, Richard L

    2016-04-01

    Two cardiovascular outcome trials established niacin 3 g daily prevents hard cardiac events. However, as detailed in part I of this series, an extended-release (ER) alternative at only 2 g nightly demonstrated no comparable benefits in two outcome trials, implying the alternative is not equivalent to the established cardioprotective regimen. Since statins leave a significant treatment gap, this presents a major opportunity for developers. Importantly, the established regimen is cardioprotective, so the pathway is likely beneficial. Moreover, though effective, the established cardioprotective regimen is cumbersome, limiting clinical use. At the same time, the ER alternative has been thoroughly discredited as a viable substitute for the established cardioprotective regimen. Therefore, by exploiting the pathway and skillfully avoiding the problems with the established cardioprotective regimen and the ER alternative, developers could validate cardioprotective variations facing little meaningful competition from their predecessors. Thus, shrewd developers could effectively tap into a gold mine at the grave of the ER alternative. The GPR109A receptor was discovered a decade ago, leading to a large body of evidence commending the niacin pathway to a lower cardiovascular risk beyond statins. While mediating niacin's most prominent adverse effects, GPR109A also seems to mediate anti-lipolytic, anti-inflammatory, and anti-atherogenic effects of niacin. Several developers are investing heavily in novel strategies to exploit niacin's therapeutic pathways. These include selective GPR109A receptor agonists, niacin prodrugs, and a niacin metabolite, with encouraging early phase human data. In part II of this review, we summarize the accumulated results of these early phase studies of emerging niacin mimetics.

  4. Effects of hypobaric pressure on human skin: implications for cryogen spray cooling (part II).

    Science.gov (United States)

    Aguilar, Guillermo; Franco, Walfre; Liu, Jie; Svaasand, Lars O; Nelson, J Stuart

    2005-02-01

    Clinical results have demonstrated that dark purple port wine stain (PWS) birthmarks respond favorably to laser induced photothermolysis after the first three to five treatments. Nevertheless, complete blanching is rarely achieved and the lesions stabilize at a red-pink color. In a feasibility study (Part I), we showed that local hypobaric pressure on PWS human skin prior to laser irradiation induced significant lesion blanching. The objective of the present study (Part II) is to investigate the effects of hypobaric pressures on the efficiency of cryogen spray cooling (CSC), a technique that assists laser therapy of PWS and other dermatoses. Experiments were carried out within a suction cup and vacuum chamber to study the effect of hypobaric pressure on the: (1) interaction of cryogen sprays with human skin; (2) spray atomization; and (3) thermal response of a model skin phantom. A high-speed camera was used to acquire digital images of spray impingement on in vivo human skin and spray cones generated at different hypobaric pressures. Subsequently, liquid cryogen was sprayed onto a skin phantom at atmospheric and 17, 34, 51, and 68 kPa (5, 10, 15, and 20 in Hg) hypobaric pressures. A fast-response temperature sensor measured sub-surface phantom temperature as a function of time. Measurements were used to solve an inverse heat conduction problem to calculate surface temperatures, heat flux, and overall heat extraction at the skin phantom surface. Under hypobaric pressures, cryogen spurts did not produce skin indentation and only minimal frost formation. Sprays also showed shorter jet lengths and better atomization. Lower minimum surface temperatures and higher overall heat extraction from skin phantoms were reached. The combined effects of hypobaric pressure result in more efficient cryogen evaporation that enhances heat extraction and, therefore, improves the epidermal protection provided by CSC. (c) 2005 Wiley-Liss, Inc.

  5. Reciprocating gait orthosis powered with electrical muscle stimulation (RGO II). Part II: Medical evaluation of 70 paraplegic patients.

    Science.gov (United States)

    Solomonow, M; Reisin, E; Aguilar, E; Baratta, R V; Best, R; D'Ambrosia, R

    1997-05-01

    Medical evaluation was performed on a group of paraplegics who were trained to walk with the Reciprocating Gait Orthosis powered with electrical muscle stimulation (RGO II). The evaluation included changes in spasticity, cholesterol level, bone metabolism, cardiac output and stroke volume, vital capacity, knee extensors torque, and heart rate at the end of a 30-meter walk. After an average of 14 weeks of training during which patients walked for 3 hours per week, significant reductions in spasticity, total cholesterol and low-density lipids, hydroxyproline/creatinine ratio, and increased knee extensor torque were evident. The data also showed that improvements occurred in the calcium/creatinine ratio, serum calcium and alkaline phosphatase levels, cardiac output and stroke volume, and vital capacity, yet these improvements were not statistically significant. The final heart rate at the end of a 30-meter walk showed that the RGO II required only a moderate level of exertion, which was found to be the lowest among the other mechanical or muscle stimulation orthoses available to paraplegics. It was concluded that the limited but reasonable level of functional regain provided by the RGO II is associated with a general improvement in the paraplegic's physiological condition if used for a minimum of 3 to 4 hours per week.

  6. Testing and Analysis of a Composite Non-Cylindrical Aircraft Fuselage Structure . Part II; Severe Damage

    Science.gov (United States)

    Przekop, Adam; Jegley, Dawn C.; Lovejoy, Andrew E.; Rouse, Marshall; Wu, Hsi-Yung T.

    2016-01-01

    The Environmentally Responsible Aviation Project aimed to develop aircraft technologies enabling significant fuel burn and community noise reductions. Small incremental changes to the conventional metallic alloy-based 'tube and wing' configuration were not sufficient to achieve the desired metrics. One airframe concept identified by the project as having the potential to dramatically improve aircraft performance was a composite-based hybrid wing body configuration. Such a concept, however, presented inherent challenges stemming from, among other factors, the necessity to transfer wing loads through the entire center fuselage section which accommodates a pressurized cabin confined by flat or nearly flat panels. This paper discusses a finite element analysis and the testing of a large-scale hybrid wing body center section structure developed and constructed to demonstrate that the Pultruded Rod Stitched Efficient Unitized Structure concept can meet these challenging demands of the next generation airframes. Part II of the paper considers the final test to failure of the test article in the presence of an intentionally inflicted severe discrete source damage under the wing up-bending loading condition. Finite element analysis results are compared with measurements acquired during the test and demonstrate that the hybrid wing body test article was able to redistribute and support the required design loads in a severely damaged condition.

  7. Tutorial on Feedback Control of Flows, Part II: Diagnostics and Feedback Control of Mixing

    Directory of Open Access Journals (Sweden)

    Ole M. Aamo

    2002-10-01

    Full Text Available Control of fluid flows span a wide variety of specialities. In Part II of this tutorial, we focus on diagnostics of mixing and the problem of enhancing mixing by boundary feedback control. Diagnostic tools from dynamical systems theory are presented that enable detection and quantification of chaotic transport in periodically perturbed systems. However, real systems are generally not periodic, and available measurements or simulations are finite in time. A method for quantifying mixing in finite-time velocity fields is discussed, and applied to data obtained from simulations of the 2D controlled channel flow. Mixing has traditionally been brought on by open-loop control strategies, such as stirring, jet injection or mixing valves. Applications of active feedback to mixing problems are scarce in the literature, but the idea is currently drawing attention from various research groups. Feedback laws for the purpose of mixing enhancement in 2D and 3D pipe flow are presented, and simulations show that they induce strong mixing.

  8. Familial breast cancer. Part II: Relationships with histology, staging, steroid receptors and serum tumor markers.

    Science.gov (United States)

    Gavrilov, I; Nacheva, M; Tzingilev, D

    2002-01-01

    To identify differences in clinical characteristics, histological features, hormone receptor status, and tumor marker expression between patients with sporadic and familial breast cancer. As in the previous Part I of this study, two groups of women with breast cancer were compared. The first group (group I) included 504 patients with a family history of breast cancer. The second (control) group (group II) consisted of 300 patients not reporting such a history in their relatives. The examined parameters in this report were stage and axillary lymph node involvement at the time of the initial diagnosis, treatment methods, hormone receptor status, and serum levels of the tumor markers CEA and CA 15.3. The data were processed and analysed using the SPSS statistical package. The statistical significance of differences between groups and subgroups was evaluated by x(2) Pearson's test and Student's paired t-test. Compared to sporadic cases, patients with familial breast cancer were more often diagnosed at an advanced III or IV stage; metastatic involvement of the regional lymph nodes was more frequent in group I patients. In the same group more radical surgical procedures combined with chemotherapy and local irradiation were performed. In group I the percentage of negative hormone receptors was higher (35.3% versus 22.6%; p result of their particular characteristics, these patients require more radical surgical techniques combined with pre- or postoperative local radiotherapy and systemic chemotherapy.

  9. Reproduction in the space environment: Part II. Concerns for human reproduction

    Science.gov (United States)

    Jennings, R. T.; Santy, P. A.

    1990-01-01

    Long-duration space flight and eventual colonization of our solar system will require successful control of reproductive function and a thorough understanding of factors unique to space flight and their impact on gynecologic and obstetric parameters. Part II of this paper examines the specific environmental factors associated with space flight and the implications for human reproduction. Space environmental hazards discussed include radiation, alteration in atmospheric pressure and breathing gas partial pressures, prolonged toxicological exposure, and microgravity. The effects of countermeasures necessary to reduce cardiovascular deconditioning, calcium loss, muscle wasting, and neurovestibular problems are also considered. In addition, the impact of microgravity on male fertility and gamete quality is explored. Due to current constraints, human pregnancy is now contraindicated for space flight. However, a program to explore effective countermeasures to current constraints and develop the required health care delivery capability for extended-duration space flight is suggested. A program of Earth- and space-based research to provide further answers to reproductive questions is suggested.

  10. Coordinator(a) de Servicios Clinicos. Parte I (Unidad I-IV). Parte II (Unidad V-VI). Guia. Documento de Trabajo (Clinical Services Coordinator. Part I. Units I-IV. Part II. Units V-VI. Guide. Working Document).

    Science.gov (United States)

    Puerto Rico State Dept. of Education, Hato Rey. Area for Vocational and Technical Education.

    This guide is intended for instructing secondary students in the occupation of clinical services coordinator in a hospital. The first part contains four units on the following subjects: the occupation of clinical services coordinator; interpersonal relationships; ethical/legal aspects; and communications (telephone, intercom, and others). For each…

  11. Correction of Class II malocclusion and soft tissue profile in an adult patient

    OpenAIRE

    Aditi Gaur; Sandhya Maheshwari; Sanjeev Kumar Verma

    2016-01-01

    Treatment of Class II malocclusion in nongrowing individuals is a challenging situation for the clinician. Class II malocclusion with bialveolar protrusion often dictates premolar extractions with maximum anchorage. The present article describes the case of an adult female with skeletal Class II malocclusion, bimaxillary protrusion, increased overjet, deep bite, lip protrusion, everted lower lip, deep mentolabial sulcus, and lip incompetence. To correct the malocclusion, all four first premol...

  12. Developing guidelines for economic evaluation of environmental impacts in EIAs. Part II: Case studies and dose-response literature

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    This Part II of the report contains full versions of the case studies for air, water and land (Chapters 2-4), which were only summarised in Part I. In addition, during the work the research team has collected a large amount of literature and information on dose response relationships for air and water pollution relevant to China. This information is included as Chapters 5 and 6.

  13. HLA class I and class II HLA DRB profiles in Egyptian children with rheumatic valvular disease.

    Science.gov (United States)

    El-Hagrassy, Nashwa; El-Chennawi, Farha; Zaki, Maysaa El-Sayed; Fawzy, Hossam; Zaki, Adel; Joseph, Nabeil

    2010-07-01

    Poststreptococcal sequelae, especially acute rheumatic fever/rheumatic heart disease continues to occur in significant proportions in many parts of the world, especially in less developed countries. An important factor in the study of rheumatic heart disease is the human genetic susceptibility to the disease. The aim of the present study was to detect the most prevalent HLA class I and class II types associated with risk of rheumatic heart disease in Egyptian children. Our study was performed on 100 patients with rheumatic valvular heart diseases and 71 control subjects. Patients were recruited from the Heart Institute, Embaba, Egypt. HLA typing for HLA class I was performed by serotyping and HLDR allele genotyping was performed using INNO-LiPA kits. In the study of HLA class I, there was a statistically significant increase in the B5 allele (P = 0.03; odds ratio, 3.46 [1.12-10.72]) in patients compared to controls, while B49 and B52 alleles (P = 0.004 and P = 0.02) were found in controls only. There was a statistically significant increase in HLA DR* 04-02, 3.46 (1.12-10.72) and HLA DR *10-0101 5.75 (1.27-25.98) in patients. Meanwhile HLA DR*1309120 was found only in controls (P = 0.02). Our study provides further information on the genetic predisposition for rheumatic valvular disease and the protective genotypes in rheumatic heart disease. Further insight into the molecular mechanisms of the disease will be a useful tool for predicting clinical outcome in those patients and, thus, potentially offer new means and approaches to treatment and prophylaxis, including a potential vaccine.

  14. National Environmental/Energy Workforce Assessment, Phase II, Post-Secondary Education Profile: Pesticides.

    Science.gov (United States)

    National Field Research Center Inc., Iowa City, IA.

    Pesticide- and toxicology-related programs were reviewed in 21 states and in 26 academic institutions. These programs represent a sample, only, of the various programs available nationwide. Enrollment profiles are given for both pesticide and toxicology programs. The programs described in these profiles are served by a total of 620 faculty.…

  15. Terverticillate penicillia studied by direct electrospray mass spectrometric profiling of crude extracts II. Database and identification

    DEFF Research Database (Denmark)

    Smedsgaard, Jørn

    1997-01-01

    A mass spectral database was built using standard instrument software from 678 electrospray mass spectra (mass profiles) from crude fungal extracts of terverticillate taxa within the genus Penicillium. The match factors calculated from searching all the mass profiles stored in the database were u...

  16. Recession, Retrenchment, and Recovery: State Higher Education Funding & Student Financial Aid. Volume II: State Profiles

    Science.gov (United States)

    Ambrose, Allison S.; Hines, Edward R.; Hodel, Ross A.; Kelly, Kathleen F.; Mushrush, Christopher E., Pruden, Sheila J.; Vogt, W. Paul

    2006-01-01

    This report is a companion to "Recession, Retrenchment and Recovery: Higher Education Funding and Student Financial Aid" (ED502180). It provides profiles of individual states and their performance on a variety of measures used in the economic and fiscal analysis of the Recession, Retrenchment and Recovery project. The profiles describe the results…

  17. The Design of Research Laboratories. Part I: A General Assessment. Part II: Air Conditioning and Conditioned Rooms.

    Science.gov (United States)

    Legget, R. F.; Hutcheon, N. B.

    Design factors in the planning of research laboratories are described which include--(1) location, (2) future expansion, (3) internal flexibility, (4) provision of services, (5) laboratory furnishing, (6) internal traffic, (7) space requirements, and (8) building costs. A second part discusses air-conditioning and conditioned rooms--(1)…

  18. Industry Wage Surveys: Banking and Life Insurance, December 1976. Part I--Banking. Part II--Life Insurance. Bulletin 1988.

    Science.gov (United States)

    Barsky, Carl

    This report presents the results of a survey conducted by the Bureau of Labor Statistics to determine wages and related benefits in (1) the banking industry and (2) for employees in home offices and regional head offices of life insurance carriers. Part 1 discusses banking industry characteristics and presents data for tellers and selected…

  19. Study of diffuse H II regions potentially forming part of the gas streams around Sgr A*

    Science.gov (United States)

    Armijos-Abendaño, J.; López, E.; Martín-Pintado, J.; Báez-Rubio, A.; Aravena, M.; Requena-Torres, M. A.; Martín, S.; Llerena, M.; Aldás, F.; Logan, C.; Rodríguez-Franco, A.

    2018-02-01

    We present a study of diffuse extended ionised gas toward three clouds located in the Galactic Centre (GC). One line of sight (LOS) is toward the 20 km s-1 cloud (LOS-0.11) in the Sgr A region, another LOS is toward the 50 km s-1 cloud (LOS-0.02), also in Sgr A, while the third is toward the Sgr B2 cloud (LOS+0.693). The emission from the ionised gas is detected from Hnα and Hmβ radio recombination lines (RRLs). Henα and Hemβ RRL emission is detected with the same n and m as those from the hydrogen RRLs only toward LOS+0.693. RRLs probe gas with positive and negative velocities toward the two Sgr A sources. The Hmβ to Hnα ratios reveal that the ionised gas is emitted under local thermodynamic equilibrium conditions in these regions. We find a He to H mass fraction of 0.29±0.01 consistent with the typical GC value, supporting the idea that massive stars have increased the He abundance compared to its primordial value. Physical properties are derived for the studied sources. We propose that the negative velocity component of both Sgr A sources is part of gas streams considered previously to model the GC cloud kinematics. Associated massive stars with what are presumably the closest H II regions to LOS-0.11 (positive velocity gas), LOS-0.02 and LOS+0.693 could be the main sources of UV photons ionising the gas. The negative velocity components of both Sgr A sources might be ionised by the same massive stars, but only if they are in the same gas stream.

  20. The 183-WSL Fast Rain Rate Retrieval Algorithm. Part II: Validation Using Ground Radar Measurements

    Science.gov (United States)

    Laviola, Sante; Levizzani, Vincenzo

    2014-01-01

    The Water vapour Strong Lines at 183 GHz (183-WSL) algorithm is a method for the retrieval of rain rates and precipitation type classification (convectivestratiform), that makes use of the water vapor absorption lines centered at 183.31 GHz of the Advanced Microwave Sounding Unit module B (AMSU-B) and of the Microwave Humidity Sounder (MHS) flying on NOAA-15-18 and NOAA-19Metop-A satellite series, respectively. The characteristics of this algorithm were described in Part I of this paper together with comparisons against analogous precipitation products. The focus of Part II is the analysis of the performance of the 183-WSL technique based on surface radar measurements. The ground truth dataset consists of 2.5 years of rainfall intensity fields from the NIMROD European radar network which covers North-Western Europe. The investigation of the 183-WSL retrieval performance is based on a twofold approach: 1) the dichotomous statistic is used to evaluate the capabilities of the method to identify rain and no-rain clouds; 2) the accuracy statistic is applied to quantify the errors in the estimation of rain rates.The results reveal that the 183-WSL technique shows good skills in the detection of rainno-rain areas and in the quantification of rain rate intensities. The categorical analysis shows annual values of the POD, FAR and HK indices varying in the range 0.80-0.82, 0.330.36 and 0.39-0.46, respectively. The RMSE value is 2.8 millimeters per hour for the whole period despite an overestimation in the retrieved rain rates. Of note is the distribution of the 183-WSL monthly mean rain rate with respect to radar: the seasonal fluctuations of the average rainfalls measured by radar are reproduced by the 183-WSL. However, the retrieval method appears to suffer for the winter seasonal conditions especially when the soil is partially frozen and the surface emissivity drastically changes. This fact is verified observing the discrepancy distribution diagrams where2the 183-WSL

  1. Transcriptomic profiles of peripheral white blood cells in type II diabetes and racial differences in expression profiles

    Directory of Open Access Journals (Sweden)

    Mao Jinghe

    2011-12-01

    Full Text Available Abstract Background Along with obesity, physical inactivity, and family history of metabolic disorders, African American ethnicity is a risk factor for type 2 diabetes (T2D in the United States. However, little is known about the differences in gene expression and transcriptomic profiles of blood in T2D between African Americans (AA and Caucasians (CAU, and microarray analysis of peripheral white blood cells (WBCs from these two ethnic groups will facilitate our understanding of the underlying molecular mechanism in T2D and identify genetic biomarkers responsible for the disparities. Results A whole human genome oligomicroarray of peripheral WBCs was performed on 144 samples obtained from 84 patients with T2D (44 AA and 40 CAU and 60 healthy controls (28 AA and 32 CAU. The results showed that 30 genes had significant difference in expression between patients and controls (a fold change of 1.4 with a P value Conclusions These newly identified genetic markers in WBCs provide valuable information about the pathophysiology of T2D and can be used for diagnosis and pharmaceutical drug design. Our results also found that AA and CAU patients with T2D express genes and pathways differently.

  2. The new production theory for health care through clinical reengineering: a study of clinical guidelines--Part II.

    Science.gov (United States)

    Sharp, J R

    1995-01-01

    In Part I of this two-part article, in the December 1994 issue of the journal, the author discussed the manufacturing theories of Peter Drucker in terms of their applicability for the health care field. He concluded that Drucker's four principles and practices of manufacturing--statistical quality control, manufacturing accounting, modular organization, and systems approach--do have application to the health care system. Clinical guidelines, a variation on the Drucker theory, are a specific example of the manufacturing process in health. The performance to date of some guidelines and their implications for the health care reform debate are discussed in Part II of the article.

  3. Control of uncertain systems by feedback linearization with neural networks augmentation. Part II. Controller validation by numerical simulation

    Directory of Open Access Journals (Sweden)

    Adrian TOADER

    2010-09-01

    Full Text Available The paper was conceived in two parts. Part I, previously published in this journal, highlighted the main steps of adaptive output feedback control for non-affine uncertain systems, having a known relative degree. The main paradigm of this approach was the feedback linearization (dynamic inversion with neural network augmentation. Meanwhile, based on new contributions of the authors, a new paradigm, that of robust servomechanism problem solution, has been added to the controller architecture. The current Part II of the paper presents the validation of the controller hereby obtained by using the longitudinal channel of a hovering VTOL-type aircraft as mathematical model.

  4. Interobserver reliability and diagnostic performance of Chiari II malformation measures in MR imaging-part 2

    NARCIS (Netherlands)

    Geerdink, Niels; van der Vliet, Ton; Rotteveel, Jan J.; Feuth, Ton; Roeleveld, Nel; Mullaart, Reinier A.

    Brain MR imaging is essential in the assessment of Chiari II malformation in clinical and research settings concerning spina bifida. However, the interpretation of MR images of the malformation is not always straightforward. Morphometric analyses of the extent of Chiari II malformation may improve

  5. Interobserver reliability and diagnostic performance of Chiari II malformation measures in MR imaging--part 2.

    NARCIS (Netherlands)

    Geerdink, N.; Vliet, T. van der; Rotteveel, J.J.; Feuth, T.; Roeleveld, N.; Mullaart, R.A.

    2012-01-01

    PURPOSE: Brain MR imaging is essential in the assessment of Chiari II malformation in clinical and research settings concerning spina bifida. However, the interpretation of MR images of the malformation is not always straightforward. Morphometric analyses of the extent of Chiari II malformation may

  6. Effect of morphology on water sorption in cellular solid foods. Part II: sorption in cereal crackers

    NARCIS (Netherlands)

    Esveld, D.C.; Sman, van der R.G.M.; Witek, M.M.; Windt, C.W.; As, van H.; Duynhoven, van J.P.M.; Meinders, M.B.J.

    2012-01-01

    Experimental dynamical moisture profiles of crackers with a fine and coarse morphology are successfully predicted using a pore scale network model. Experimental profiles are obtained using a single point imaging (SPI) NMR technique that enables 3D mapping of the moisture content of relatively

  7. Contributions to North American Ethnology, Volume II, Part II: The Klamath Indians of southwestern Oregon: dictionary of the Klamath language

    Science.gov (United States)

    Gatschet, Albert Samuel; Powell, John Wesley

    1890-01-01

    The present Dictionary, divided in two parts, contains the lexical portion of an Oregonian language never before reduced to writing. In view of the numerous obstacles and difficulties encountered in the preparation of such a work, a few hints upon its origin and tendencies will be of service in directing the studies of those who wish to acquire a more intimate knowledge of this energetic and well developed western language.

  8. Establish the CNC machining strategy in relation with geometric complexity of the parts made from aluminum alloy extruded profile

    Science.gov (United States)

    Moldovan, Ş. A.; Cosma, M.; Năsui, V.

    2017-05-01

    In this paper we present a technological problem encountered in the machining accuracy of the parts for aerospace made of aluminum alloy extruded profile with length up to 10 meters. Those parts have very tight tolerances and on milling process appear several factors that influence the repeatability of machining processes. Several factors must be considered when developing the machining process for a specific part, including: establishing the machining strategy in relation with piece geometric complexity, analysis of machined parts through coordinate measuring machine and statistical analysis, to determinate the proper machining strategy for obtaining parts in tolerance. Through several tests and recording all dimensions changes during the milling process, will be modified the machining strategy. By analysing the machining strategy at different lengths of extrusions and records of dimensions fluctuations along the processing chain has been created a proper machine strategy which will obtain a repeatability of the machining process.

  9. Transcriptomic profiles of peripheral white blood cells in type II diabetes and racial differences in expression profiles.

    Science.gov (United States)

    Mao, Jinghe; Ai, Junmei; Zhou, Xinchun; Shenwu, Ming; Ong, Manuel; Blue, Marketta; Washington, Jasmine T; Wang, Xiaonan; Deng, Youping

    2011-12-23

    Along with obesity, physical inactivity, and family history of metabolic disorders, African American ethnicity is a risk factor for type 2 diabetes (T2D) in the United States. However, little is known about the differences in gene expression and transcriptomic profiles of blood in T2D between African Americans (AA) and Caucasians (CAU), and microarray analysis of peripheral white blood cells (WBCs) from these two ethnic groups will facilitate our understanding of the underlying molecular mechanism in T2D and identify genetic biomarkers responsible for the disparities. A whole human genome oligomicroarray of peripheral WBCs was performed on 144 samples obtained from 84 patients with T2D (44 AA and 40 CAU) and 60 healthy controls (28 AA and 32 CAU). The results showed that 30 genes had significant difference in expression between patients and controls (a fold change of 1.4 with a P value <0.05). These known genes were mainly clustered in three functional categories: immune responses, lipid metabolism, and organismal injury/abnormaly. Transcriptomic analysis also showed that 574 genes were differentially expressed in AA diseased versus AA control, compared to 200 genes in CAU subjects. Pathway study revealed that "Communication between innate and adaptive immune cells"/"Primary immunodeficiency signaling" are significantly down-regulated in AA patients and "Interferon signaling"/"Complement System" are significantly down-regulated in CAU patients. These newly identified genetic markers in WBCs provide valuable information about the pathophysiology of T2D and can be used for diagnosis and pharmaceutical drug design. Our results also found that AA and CAU patients with T2D express genes and pathways differently.

  10. Improving Statistical Process Monitoring of Quality Characteristic with Polynomial Profile in Phase II

    Directory of Open Access Journals (Sweden)

    Amirhossein Amiri

    2012-03-01

    Full Text Available Profile monitoring is a new research subject in Statistical Process Control which has been recently considered by many researchers. Profile describes the relationship between a response variable and one or more independent variables. This relationship is often modeled using regression which can be simple linear, multiple linear, polynomial or sometimes nonlinear. To monitor polynomial profiles, some methods have been developed, the best of which is the orthogonal polynomial approach. One of the disadvantages of this method is the large number of control charts which are simultaneously used. In this paper, a new approach has been proposed based on orthogonal polynomial approach, in which only two control charts are used to monitor a kth-order polynomial profile. Simulation findings and average run length (ARL curve analysis imply better performance of the proposed approach compared to the existing approach. Also, using the proposed approach is much easier in practice.

  11. Profiles of Automotive Suppliers Industries--Engineered Mechanical Components and Systems : Volume II, Appendices.

    Science.gov (United States)

    1981-09-01

    The profile describes and analyzes that segment of the automotive supplier industry which provides engineered mechanical components/assemblies/systems to the prime auto manufacturers. It presents an overview of the role and structure of this industry...

  12. An inverse Compton scattering (ICS) model of pulsar emission. II. Frequency behavior of pulse profiles

    Science.gov (United States)

    Qiao, G. J.; Liu, J. F.; Zhang, B.; Han, J. L.

    2001-10-01

    The shapes of pulse profiles, especially their variations with respect to observing frequencies, are very important to understand emission mechanisms of pulsars. However, no previous attempt has been made to interpret their complicated phenomenology. In this paper, we present theoretical simulations for the integrated pulse profiles and their frequency evolution within the framework of the inverse Compton scattering (ICS) model proposed by Qiao (\\cite{Qiao88}) and Qiao & Lin (\\cite{Qiao98}). Using the phase positions of the pulse components predicted by the ``beam-frequency figure'' of the ICS model, we present Gaussian fits to the multi-frequency pulse profiles for some pulsars. It is shown that the model can reproduce various types of the frequency evolution behaviors of pulse profiles observed.

  13. Gemini NIFS survey of feeding and feedback processes in nearby active galaxies - II. The sample and surface mass density profiles

    Science.gov (United States)

    Riffel, R. A.; Storchi-Bergmann, T.; Riffel, R.; Davies, R.; Bianchin, M.; Diniz, M. R.; Schönell, A. J.; Burtscher, L.; Crenshaw, M.; Fischer, T. C.; Dahmer-Hahn, L. G.; Dametto, N. Z.; Rosario, D.

    2018-02-01

    We present and characterize a sample of 20 nearby Seyfert galaxies selected for having BAT 14-195 keV luminosities LX ≥ 1041.5 erg s-1, redshift z ≤ 0.015, being accessible for observations with the Gemini Near-Infrared Field Spectrograph (NIFS) and showing extended [O III]λ5007 emission. Our goal is to study Active Galactic Nucleus (AGN) feeding and feedback processes from near-infrared integral-field spectra, which include both ionized (H II) and hot molecular (H2) emission. This sample is complemented by other nine Seyfert galaxies previously observed with NIFS. We show that the host galaxy properties (absolute magnitudes MB, MH, central stellar velocity dispersion and axial ratio) show a similar distribution to those of the 69 BAT AGN. For the 20 galaxies already observed, we present surface mass density (Σ) profiles for H II and H2 in their inner ˜500 pc, showing that H II emission presents a steeper radial gradient than H2. This can be attributed to the different excitation mechanisms: ionization by AGN radiation for H II and heating by X-rays for H2. The mean surface mass densities are in the range (0.2 ≤ ΣH II ≤ 35.9) M⊙ pc-2, and (0.2 ≤ ΣH2 ≤ 13.9)× 10-3 M⊙ pc-2, while the ratios between the H II and H2 masses range between ˜200 and 8000. The sample presented here will be used in future papers to map AGN gas excitation and kinematics, providing a census of the mass inflow and outflow rates and power as well as their relation with the AGN luminosity.

  14. Comparison of MAX-DOAS profiling algorithms during CINDI-2 - Part 1: aerosols

    Science.gov (United States)

    Friess, Udo; Hendrick, Francois; Tirpitz, Jan-Lukas; Apituley, Arnoud; van Roozendael, Michel; Kreher, Karin; Richter, Andreas; Wagner, Thomas

    2017-04-01

    The second Cabauw Intercomparison campaign for Nitrogen Dioxide measuring Instruments (CINDI-2) took place at the Cabauw Experimental Site for Atmospheric Research (CESAR; Utrecht area, The Netherlands) from 25 August until 7 October 2016. CINDI-2 was aiming at assessing the consistency of MAX-DOAS slant column density measurements of tropospheric species (NO2, HCHO, O3, and O4) relevant for the validation of future ESA atmospheric Sentinel missions, through coordinated operation of a large number of DOAS and MAXDOAS instruments from all over the world. An important objective of the campaign was to study the relationship between remote-sensing column and profile measurements of the above species and collocated reference ancillary observations. For this purpose, the CINDI-2 Profiling Task Team (CPTT) was created, involving 22 groups performing aerosol and trace gas vertical profile inversion using dedicated MAX-DOAS profiling algorithms, as well as the teams responsible for ancillary profile and surface concentration measurements (NO2 analysers, NO2 sondes, NO2 and Raman LIDARs, CAPS, Long-Path DOAS, sun photometer, nephelometer, etc). The main purpose of the CPTT is to assess the consistency of the different profiling tools for retrieving aerosol extinction and trace gas vertical profiles through comparison exercises using commonly defined settings and to validate the retrievals with correlative observations. In this presentation, we give an overview of the MAX-DOAS vertical profile comparison results, focusing on the retrieval of aerosol extinction profiles, with the trace gas retrievals being presented in a companion abstract led by F. Hendrick. The performance of the different algorithms is investigated with respect to the variable visibility and cloud conditions encountered during the campaign. The consistency between optimal-estimation-based and parameterized profiling tools is also evaluated for these different conditions, together with the level of agreement

  15. Modulus of elasticity, creep and shrinkage of concrete, phase II : part 1, creep study, final report.

    Science.gov (United States)

    2009-10-01

    A laboratory testing program was performed to evaluate the physical and mechanical properties of typical Class II, IV, V, and VI concrete mixtures made with a Miami Oolite limestone, a Georgia granite, and a lightweight aggregate Stalite, including c...

  16. Citrus fruits. Part II. Chemistry, technology, and quality evaluation. B. Technology.

    Science.gov (United States)

    Ranganna, S; Govindarajan, V S; Ramana, K V

    1983-01-01

    In Part II of this review on citrus fruits, the literature on chemistry, technology, and quality evaluation are critically considered. Sweet oranges, mandarin, grapefruit, lemon, and lime are generally used for processing. The literature on chemical components of citrus fruit which include sugars, polysaccharides, organic acids, nitrogenous constituents and lipids; carotenoids which contribute to color; vitamins and minerals and flavonoids; limonoids, some of which impart bitterness to the juice; and the volatile components which contribute to aroma were reviewed in section A. Chilled and pasteurized juices, juice concentrates, and beverages are the important products manufactured commercially, and to a limited extent powdered citrus juices, canned segments, and marmalades. The literature on the manufacture of these products also as new types of juice and oil extractors; TASTE and other types of evaporators; tank farms to store juice and concentrate in bulk; aseptic filling in bulk containers and retail packs; alternate flexible and rigid containers other than glass and tin; and recovery of volatile flavoring constituents during juice processing are some of the important technological developments in the recent past and have been discussed in this section. Bitterness in citrus juices and its control, composition of cloud, and its stability and changes during storage have been reviewed. Essential oils, pectin, frozen and dried juice sacs, dried pulp and molasses, flavonoids, seed oil, and meal are the important byproducts, the manufacture of which is given in essential details. Generally, consumers judge the product on the basis of its sensory attributes. The quality of finished product is dependent upon the raw materials used and control of processes. In section C, the U.S. Department of Agriculture (USDA) standards for different products, physicochemical and microbiological parameters prescribed as indices of quality of fruit, juice, concentrate, and other

  17. Diabetes area patent participation analysis - part II: years 2011-2016.

    Science.gov (United States)

    Boehm, Markus; Crawford, Matthew; Moscovitz, Jamie E; Carpino, Philip A

    2018-02-01

    Diabetes is a metabolic disease characterized by elevated levels of plasma glucose. When untreated, diabetes increases the risk of developing co-morbidities such as cardiovascular disease. Several drugs, often used as part of combination therapies, have been approved to treat the disease, but these drugs will eventually fail to effectively control blood glucose levels, at which point insulin replacement therapy is required. A medical need exists for new antidiabetic drugs that exhibit good efficacy with improved safety/toleration profiles and can be added on top of existing therapies, or that can provide additional benefits beyond glucose lowering such as pancreatic beta (β)-cell protection. Areas covered: This review analyzes drug targets and applicants of patents that published between 2011-2016 claiming novel small or large molecules for the treatment of diabetes, and compares the results to the 2008-2010 time period. Expert opinion: A majority of patent activity around the discovery of new antidiabetic drugs in 2011-2016 was directed against 15 targets, most of which were also the focus of drug discovery efforts in the 2008-2010 time period. The top targets by total patent counts were DPP4, GLP1R, INSR, GPR119, and SGLT2 (SLC5A2). With the exception of GPR119, these are the pharmacological targets of some of the best-selling antidiabetic drugs currently on the market. The top targets of patent families with the largest size counts, a metric useful in assessing patent value and applicant interest, were AMPK, CALCR, DPP4, and GLP1R. The patent analysis identified several emerging targets with greater patent activity in 2011-2016 compared to 2008-2010, including FFAR1, FFAR4, and FGFR1. Most of the patent activity in 2011-2016 was directed at established and precedented diabetes targets, the modulation of which may lead to improvements in glucose control and a delay in the progression of the disease. Few targets were identified that promote pancreatic

  18. Esthetics in periodontics: covering denuded root surfaces using free gingival grafts without citric acid, Part II: a report on 14 teeth in 10 patients.

    Science.gov (United States)

    Levine, R A

    1989-12-01

    Part I of this series described the history and reviewed various techniques of free gingival graft usage without citric acid. Part II of this series on periodontics describes 10 successful case reports.

  19. Propriedades termofísicas de soluções-modelo similares a sucos: parte II Thermophysical properties of model solutions similar to juice: part II

    Directory of Open Access Journals (Sweden)

    Sílvia Cristina Sobottka Rolim de Moura

    2005-09-01

    Full Text Available Propriedades termofísicas, densidade e viscosidade de soluções-modelo similares a sucos foram determinadas experimentalmente. Os resultados foram comparados aos preditos por modelos matemáticos (STATISTICA 6.0 e obtidos da literatura em função da sua composição química. Para definição das soluções-modelo, foi realizado um planejamento estrela, mantendo-se fixa a quanti-dade de ácido (1,5% e variando-se a água (82-98,5%, o carboidrato (0-15% e a gordura (0-1,5%. A densidade foi determinada em picnômetro. A viscosidade foi determinada em viscosímetro Brookfield modelo LVF. A condutividade térmica foi calculada com o conhecimento das propriedades difusividade térmica e calor específico (apresentados na Parte I deste trabalho MOURA [7] e da densidade. Os resultados de cada propriedade foram analisados através de superfícies de respostas. Foram encontrados resultados significativos para as propriedades, mostrando que os modelos encontrados representam as mudanças das propriedades térmicas e físicas dos sucos, com alterações na composição e na temperatura.Thermophysical properties, density and viscosity of model solutions similar to juices were experimentally determined. The results were compared to those predicted by mathematical models (STATISTIC 6.0 and to values mentioned in the literature, according to the chemical composition. A star planning was adopted to define model solutions composition; fixing the acid amount in 1.5% and varying water (82-98.5%, carbohydrate (0-15% and fat (0-1.5%. The density was determined by picnometer. The viscosity was determined by Brookfield LVF model viscosimeter. The thermal conductivity was calculated based on thermal diffusivity and specific heat values (presented at the 1st . Part of this paper - MOURA [7] and density. The results of each property were analyzed by the response surface method. The found results were significant, indicating that the models represent the changes of

  20. Zircônia tetragonal policristalina. Parte II: Microestrutura e resistividade elétrica Tetragonal zirconia polycrystals. Part II: Microstructure and electrical resistivity

    Directory of Open Access Journals (Sweden)

    S. K. Tadokoro

    2001-06-01

    Full Text Available Nesta segunda parte são mostrados os resultados obtidos em cerâmicas densas de ZrO2: 3% mol Y2O3 (Y-TZP e 12% mol CeO2 (Ce-TZP, analisadas por espectroscopia Raman, microscopia eletrônica de varredura, e por espectroscopia de impedância. Os resultados mostram que, para ambos tipos de amostras, é possível obter cerâmicas densas (> 95% da densidade teórica para temperaturas de sinterização inferiores a 0,45 T F (T F = temperatura de fusão. A taxa de crescimento de grãos é dependente do cátion estabilizante, sendo maior para a Ce-TZP do que para a Y-TZP. Os espectros Raman de cerâmicas sinterizadas mostram as bandas típicas associadas aos modos ativos da fase cristalográfica tetragonal. Os resultados de espectroscopia de impedância são similares aos obtidos por outros pesquisadores tanto para cerâmicas convencionais quanto nanofásicas no caso da Y-TZP. Para a Ce-TZP foi observada uma redução na condutividade extrínseca em conseqüência da maior pureza do precursor cristalizado.Results on dense ZrO2: 3 mol% Y2O3 (Y-TZP and 12 mol% CeO2 (Ce-TZP ceramics are shown in this second part. Sintered specimens were analyzed by Raman spectroscopy, scanning electron microscopy and impedance spectroscopy. The main results show that both types of solid solutions may attain a high densification (> 95% of the theoretical density for sintering temperatures lower than 0.45 T F (T F = melting temperature. The rate of grain growth is governed by the stabilizing cation and is faster for Ce-TZP than for Y-TZP. Raman spectra exhibit the six characteristic bands of the tetragonal phase for both specimens. Impedance spectroscopy results for Y-TZP do not differ from those obtained for nanophase ceramics. A reduction in the extrinsic conductivity due to the high purity of the crystallized precursor was observed for Ce-TZP specimens.

  1. Nutrição em Unidade de Cuidados Intensivos -Parte II

    Directory of Open Access Journals (Sweden)

    Cecília Mendonça

    1996-07-01

    Full Text Available RESUMO: Nesta parte II do artigo “Nutrição em Unidade de Cuidados Intensivos” os autores privilegiam a via entérica para administração de nutrientes a doentes com um aparelho gastrointestinal funcionante. Refere-se quando e como iniciar a administração entérica e as contraindicações associadas à sua utilização, as sondas utilizadas e as técnicas de colocação. Quando a administração entérica está indicada por períodos prolongados pode ser importante discutir as vaotagens da efectivação de gastrostomia ou enterostomia.A colocação indevida das sondas na árvore traqueo-brônquica, a aspiração e a diarreia são as principais complicações da administração entérica.A administração entérica pode ser realizada de forma intermitente ou contínua. O resíduo gástrico deve ser avaliado regularmente e, se houver necessidade, pode recorrer-se à utilização de procinéticos.São discutidas fórmulas especiais de administração entérica dirigidas nomeadamente aos doentes com DPOC, Insuficiência Renal e Diabetes. É focada a problemática da realimentação e sobrealimentação.Finalmente são tratadas as indicações e controlo da alimentação parentérica. SUMMARY: In the second part of “Nutrition in Intensive Care Unit” the authors emphasise the importance of enteric route for the administration of nutrients to patients with a normal condition of the gastroinstestinal tract. The rules for when and how initiate the enteric feeding and the associate contra indications, as well as the utilised catheters and techniques of implementation, are expressed in this article. When the enteric feeding is indicated for a long period of time, the advantages of gastrostomy or enterostomy, should be considered.The incorrect positioning of the feeding catheter in tracheobronchial tree

  2. Comparison of MAX-DOAS profiling algorithms during CINDI-2 - Part 2: trace gases

    Science.gov (United States)

    Hendrick, Francois; Friess, Udo; Tirpitz, Lukas; Apituley, Arnoud; Van Roozendael, Michel; Kreher, Karin; Richter, Andreas; Wagner, Thomas

    2017-04-01

    The second Cabauw Intercomparison campaign for Nitrogen Dioxide measuring Instruments (CINDI-2) took place at the Cabauw Experimental Site for Atmospheric Research (CESAR; Utrecht area, The Netherlands) from 25 August until 7 October 2016. CINDI-2 was aiming at assessing the consistency of MAX-DOAS slant column density measurements of tropospheric species (NO2, HCHO, O3, and O4) relevant for the validation of future ESA atmospheric Sentinel missions, through coordinated operation of a large number of DOAS and MAXDOAS instruments from all over the world. An important objective of the campaign was to study the relationship between remote-sensing column and profile measurements of the above species and collocated reference ancillary observations. For this purpose, the CINDI-2 Profiling Task Team (CPTT) was created, involving 22 groups performing aerosol and trace gas vertical profile inversion using dedicated MAX-DOAS profiling algorithms, as well as the teams responsible for ancillary profile and surface concentration measurements (NO2 analysers, NO2 sondes, NO2 and Raman LIDARs, CAPS, Long-Path DOAS, sunphotometer, nephelometer, etc). The main purpose of the CPTT is to assess the consistency of the different profiling tools for retrieving aerosol extinction and trace gas vertical profiles through comparison exercises using commonly defined settings and to validate the retrievals with correlative observations. In this presentation, we give an overview of the MAX-DOAS vertical profile comparison results, focusing on NO2 and HCHO, the aerosol retrievals being presented in a companion abstract led by U. Frieß. The performance of the different algorithms is investigated with respect to the various sky and weather conditions and aerosol loadings encountered during the campaign. The consistency between optimal-estimation-based and parameterized profiling tools is also evaluated for these different conditions, together with the level of agreement with available NO2 and

  3. Characterization of sugar cane bagasse: part II: fluid dynamic characteristics; Caracterizacion del bagazo de la cana de azucar: parte II: caracteristicas fluidodinamicas

    Energy Technology Data Exchange (ETDEWEB)

    Alarcon, Guillermo A. Roca [Universidad de Oriente (CEEFE/UO), Santiago de Cuba (Cuba). Centro de Estudios de Eficiencia Energetica], Emails: roca@ceefe.uo.edu.cu, grocabayamon@hotmail.com; Sanchez, Caio Glauco [Universidade Estadual de Campinas (FEM/UNICAMP), SP (Brazil). Fac. de Engenharia Mecanica], Email: caio@fem.unicamp.br; Gomez, Edgardo Olivares [Universidade Estadual de Campinas (NIPE/UNICAMP), SP (Brazil). Nucleo Interdisciplinar de Planejamento Energetico], Emails: gomez@bioware.com.br, egomez@energiabr.org.br; Cortez, Luis Augusto Barbosa [Universidade Estadual de Campinas (NIPE/FEAGRI/UNICAMP), SP (Brazil). Fac. de Engenharia Agricola. Nucleo Interdisciplinar de Planejamento Energetico], Email: cortez@reitoria.unicamp.br

    2006-07-01

    This paper is the second part of a general study about physic-geometrical and fluid-dynamics characteristic of the sugarcane bagasse particles. These properties has relevant importance on the dimensions and operation of the equipment for transport and treatment of solid particles. Was used the transport column method for the determination of the drag velocity and later on the drag coefficient of the sugarcane bagasse particles was calculated. Both, the installation and experimental technique used for materials of these characteristics are simple and innovations tools, but rigorous conceptually, thus the results obtained are reliable. Were used several sugarcane bagasse fractions of particles of known mean diameter. The properties determined were expressed as a function of Reynolds and Archimedes a dimensional criteria. The best considered model from statistical analysis (model from equation 8) was statistically validated for determined ranges of Reynolds and Archimedes. These empirical equations can be used to determine these properties in the range and conditions specified and also for modeling some processes where these fractions are employed. (author)

  4. Technical Information on the Carbonation of the EBR-II Reactor, Summary Report Part 1: Laboratory Experiments and Application to EBR-II Secondary Sodium System

    Energy Technology Data Exchange (ETDEWEB)

    Steven R. Sherman

    2005-04-01

    Residual sodium is defined as sodium metal that remains behind in pipes, vessels, and tanks after the bulk sodium metal has been melted and drained from such components. The residual sodium has the same chemical properties as bulk sodium, and differs from bulk sodium only in the thickness of the sodium deposit. Typically, sodium is considered residual when the thickness of the deposit is less than 5-6 cm. This residual sodium must be removed or deactivated when a pipe, vessel, system, or entire reactor is permanently taken out of service, in order to make the component or system safer and/or to comply with decommissioning regulations. As an alternative to the established residual sodium deactivation techniques (steam-and-nitrogen, wet vapor nitrogen, etc.), a technique involving the use of moisture and carbon dioxide has been developed. With this technique, sodium metal is converted into sodium bicarbonate by reacting it with humid carbon dioxide. Hydrogen is emitted as a by-product. This technique was first developed in the laboratory by exposing sodium samples to humidified carbon dioxide under controlled conditions, and then demonstrated on a larger scale by treating residual sodium within the Experimental Breeder Reactor II (EBR-II) secondary cooling system, followed by the primary cooling system, respectively. The EBR-II facility is located at the Idaho National Laboratory (INL) in southeastern Idaho, U.S.A. This report is Part 1 of a two-part report. It is divided into three sections. The first section describes the chemistry of carbon dioxide-water-sodium reactions. The second section covers the laboratory experiments that were conducted in order to develop the residual sodium deactivation process. The third section discusses the application of the deactivation process to the treatment of residual sodium within the EBR-II secondary sodium cooling system. Part 2 of the report, under separate cover, describes the application of the technique to residual sodium

  5. Overlooked Talent Sources and Corporate Strategies for Affirmative Action. Part II

    Science.gov (United States)

    Iacobelli, John L.; Muczyk, Jan P.

    1975-01-01

    Part Two of the two-part article describes corporate strategies for affirmative action in order to obtain the most qualified individuals available for professional positions among minority and female candidates. (Author/BP)

  6. Engineering studies on joint bar integrity, part II : finite element analysis

    Science.gov (United States)

    2014-04-02

    This paper is the second in a two-part series describing : research sponsored by the Federal Railroad Administration : (FRA) to study the structural integrity of joint bars. In Part I, : observations from field surveys of joint bar inspections : cond...

  7. THE FOOTWEAR DESIGNING SESSION USING CRISPIN DYNAMICS ENGINEER. PART II: Creating the parts, Estimating the material consumption, Grading

    Directory of Open Access Journals (Sweden)

    IOVAN-DRAGOMIR Alina

    2015-05-01

    Full Text Available The diversification and customization of products are important characteristic of the modern economy and especially of the fashion industry. Because of this, the lifetime of the footwear product is very short and result the necessity to cut the design and production time. By classic methodology, designing footwear is a very complex and laborious activity. That is because classic methodology requires many graphic executions using manual means, which consume a lot of the producer’s time. With CRISPIN Dynamics, one can visualize a range of designs on-screen; work out the costs of a new style and even cut out sample shoe components. Reliance on manual skills is largely eliminated, so the staff can work creatively, but with increased accuracy and productivity. One can even send designs to a distant office or manufacturing centre in a matter of minutes. This paper presents the basic function of CRISPIN Dynamics CAD Suite Engineer for footwear design. The process of new product development has six stapes: digitized form of the medium copy, last flatting, model drawing, creation and management of individual parts, estimation of material consumption, multiplying the designed footwear product’s pattern. This product has been developed for shoemakers who wish to ensure that their business remains competitive by increasing the efficiency, speed and accuracy of pattern development and grading.

  8. Guidelines for the management of gastroenteropancreatic neuroendocrine tumours (including bronchopulmonary and thymic neoplasms). Part II-specific NE tumour types

    DEFF Research Database (Denmark)

    Oberg, Kjell; Astrup, Lone Bording; Eriksson, Barbro

    2004-01-01

    Part II of the guidelines contains a description of epidemiology, histopathology, clinical presentation, diagnostic procedure, treatment, and survival for each type of neuroendocrine tumour. We are not only including gastroenteropancreatic tumours but also bronchopulmonary and thymic neuroendocrine...... tumours. These guidelines essentially cover basic knowledge in the diagnosis and management of the different forms of neuroendocrine tumour. We have, however, tried to give more updated information about the epidemiology and histopathology, which is essential for the clinical management of these tumours....

  9. This new science of ours: a more or less systematic history of consciousness and transcendence. Part II.

    Science.gov (United States)

    Tresan, David I

    2004-06-01

    Part I of this paper having postulated the locus of consciousness as residing in a field between primitive mind in participation mystique with the world and a transcendent ground of being, Part II takes up the nature of mind itself in this field in terms of in vivo experiences. Operations and manifestations of consciousness are inexhaustively explored in four venues: 1) Jung's life experiences, 2) Joseph Henderson's theory of psychic development, 3) Eric Voegelin's theory of consciousness and 4) the experiences of analytic patients in far reaches of very long analyses.

  10. Historia de la robótica: de Arquitas de Tarento al robot da Vinci (Parte II)

    OpenAIRE

    F. M. Sánchez-Martín; Jimenez Schlegl, Pablo; Millán, Félix; Salvador-Bayarri, Jose; Monllau, V.; Palou, Juan; Villavicencio, Humberto

    2007-01-01

    HISTORY OF ROBOTICS: FROM ARCHYTAS OF TARENTUM UNTIL DA VINCI ROBOT. (PART II) Robotic surgery is a reality. In order to to understand how new robots work is interesting to know the history of ancient (see part i) and modern robotics. The desire to design automatic machines imitating humans continued for more than 4000 years. Archytas of Tarentum (at around 400 a.C.), Heron of Alexandria, Hsieh-Fec, Al-Jazari, Bacon, Turriano, Leonardo da Vinci, Vaucanson o von Kempelen were robot inventors. ...

  11. Evaluación neurofuncional del tallo cerebral Parte II: Reflejo mandibular = Neurofunctional evaluation of brain stem. II. Mandibular reflex

    Directory of Open Access Journals (Sweden)

    Leon Sarmiento, Fidias E.

    2011-09-01

    Full Text Available El reflejo mandibular o maseterino posee conexiones nerviosas únicas, diferentes de las exhi­bidas por otros reflejos monosinápticos humanos, y permite evaluar, de forma fácil y eficien­te, el tallo cerebral por medio de la estimulación mecánica, eléctrica o magnética. Diversos estudios han demostrado la participación en este reflejo de las interneuronas del tallo cerebral y su modulación por estructuras supraespinales, que hacen parte fundamental de su integra­ción motora. El reflejo mandibular es útil para evaluar la afectación trigémino-trigeminal en polineuropatías como la diabetes, neuromiopatías como la esclerosis múltiple y en pacientes con trastornos del movimiento, con o sin disfunción oromandibular. La evaluación neuro­funcional de este reflejo craneofacial ayuda a identificar la integración sensorimotora del tallo cerebral y las posibles alteraciones de estas vías reflejas, debidas a anormalidades del sistema nervioso central o del periférico. Su apropiada ejecución e interpretación, clínica y neurológica, permite aplicar de manera más personalizada diversos protocolos de neurorre­habilitación, con el fin de ayudar a mejorar la calidad de vida de los individuos con afectación de estas vías neurales.

  12. Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling

    NARCIS (Netherlands)

    Eijkelenboom, A.; Mokry, M.; de Wit, E.; Smits, L.M.; Polderman, P.E.; van Triest, M.H.; van Boxtel, R.; Schulze, A.; de Laat, W.; Cuppen, E.; Burgering, B.M.

    2013-01-01

    Forkhead box O (FOXO) transcription factors are key players in diverse cellular processes affecting tumorigenesis, stem cell maintenance and lifespan. To gain insight into the mechanisms of FOXO-regulated target gene expression, we studied genome-wide effects of FOXO3 activation. Profiling RNA

  13. [Ablation profiles in refractive surgery. Part 1: in search of excellence].

    Science.gov (United States)

    Smadja, D; Reggiani-Mello, G; Touboul, D; Colin, J

    2012-02-01

    To provide an overview of the clinical results of various ablation profiles and discuss their technical characteristics and limitations. Literature review. With the emergence of wavefront technology, new photoablation profiles have been developed, allowing for customization of refractive treatments and reduction of nocturnal visual symptoms, which adversely affect the reputation of refractive surgery. Over the past decade, several comparative studies have been published in the literature aiming to demonstrate either the superiority of wavefront-guided correction over conventional, or one laser platform over another. However, has an ideal treatment algorithm really emerged from these studies? Does one ablation profile clearly demonstrate superiority over another, in terms of visual performance? Despite technological advances as well as improved visual results for custom versus conventional photoablation, the promise of excellence in visual performance has not been achieved with these various technologies. The concept of an individualized eye model has emerged recently, based on an optical ray tracing algorithm, and could theoretically provide an ideal ablation profile, thus fulfilling the promise of "supernormal vision". Copyright © 2011 Elsevier Masson SAS. All rights reserved.

  14. Failure mode analysis for lime/limestone FGD systems. Volume 3. Plant profiles. Part 2

    Energy Technology Data Exchange (ETDEWEB)

    Kenney, S.M.; Rosenberg, H.S.; Nilsson, L.I.O.; Oxley, J.H.

    1984-08-01

    Plant profiles are given for the following plants: Tombigbee 2, 3; Apache 2, 3; Cholla 1, 2; Four Corners 1, 2, 3; Laramie River 1; Green 1, 2; Duck Creek 1; Craig 1, 2; Conesville 5, 6; Coal Creek 1, 2; Elrama 1, 2, 3, 4; and Phillips 1, 2, 3, 4, 5, 6. (DLC)

  15. Derivados organometálicos de estanho(II - Parte 1. Compostos ciclopentadienílicos

    Directory of Open Access Journals (Sweden)

    Lima Geraldo M. de

    2001-01-01

    Full Text Available This paper provides a brief review of the chemistry of cyclopentadienyl Sn(II derivatives which includes the preparation, the molecular structure and reactivity associated with such bis-sandwich tin(II species. It is compared structural and spectroscopic results and it is also discussed how the nature of the cyclopentadienyl ring bonded to the Sn centre plays an important role in the structural and stability features of the derivatives. Bulk rings such as C5HPr i4- , C5Bz5-, C5Me4SiMe2Bu t- and C5Ph5- render air-stable and parallel ring-bonded compounds.

  16. DOE program guide for universities and other research groups. Part I. DOE Research and Development Programs; Part II. DOE Procurement and Assistance Policies/Procedures

    Energy Technology Data Exchange (ETDEWEB)

    1980-03-01

    This guide addresses the DOE responsibility for fostering advanced research and development of all energy resources, both current and potential. It is intended to provide, in a single publication, all the fundamental information needed by an institution to develop a potential working relationship with DOE. Part I describes DOE research and development programs and facilities, and identifies areas of additional research needs and potential areas for new research opportunities. It also summarizes budget data and identifies the DOE program information contacts for each program. Part II provides researchers and research administrators with an introduction to the DOE administrative policies and procedures for submission and evaluation of proposals and the administration of resulting grants, cooperative agreements, and research contracts. (RWR)

  17. Strategic Petroleum Reserve (SPR) oil storage cavern sulphur mines 2-4-5 certification tests and analysis. Part I: 1981 testing. Part II: 1982 testing

    Energy Technology Data Exchange (ETDEWEB)

    Beasley, R.R.

    1982-12-01

    Well leak tests and a cavern pressure were conducted in June through December 1981, and are described in Part I. The tests did not indicate conclusively that there was no leakage from the cavern, but the data indicate that cavern structural failure during oil storage is unlikely. The test results indicated that retesting and well workover were desirable prior to making a decision on the cavern use. Well leak tests were conducted in March through May 1982, and are described in Part II. The tests indicated that there was no significant leakage from wells 2 and 4 but that the leakage from wells 2A and 5 exceeded the DOE criterion. Because of the proximity of cavern 2-4-5 to the edge of the salt, this cavern should be considered for only one fill/withdrawal cycle prior to extensive reevaluation. 57 figures, 17 tables.

  18. Programming an interim report on the SETL project. Part I: generalities. Part II: the SETL language and examples of its use

    Energy Technology Data Exchange (ETDEWEB)

    Schwartz, J T

    1975-06-01

    A summary of work during the past several years on SETL, a new programming language drawing its dictions and basic concepts from the mathematical theory of sets, is presented. The work was started with the idea that a programming language modeled after an appropriate version of the formal language of mathematics might allow a programming style with some of the succinctness of mathematics, and that this might ultimately enable one to express and experiment with more complex algorithms than are now within reach. Part I discusses the general approach followed in the work. Part II focuses directly on the details of the SETL language as it is now defined. It describes the facilities of SETL, includes short libraries of miscellaneous and of code optimization algorithms illustrating the use of SETL, and gives a detailed description of the manner in which the set-theoretic primitives provided by SETL are currently implemented. (RWR)

  19. A critical overview of non-aqueous capillary electrophoresis. Part II: separation efficiency and analysis time.

    Science.gov (United States)

    Kenndler, Ernst

    2014-03-28

    A survey of the literature on non-aqueous capillary zone electrophoresis leaves one with the impression of a prevailing notion that non-aqueous conditions are principally more favorable than conventional aqueous media. Specifically, the application of organic solvents in capillary zone electrophoresis (CZE) is believed to provide the general advantages of superior separation efficiency, higher applicable electric field strength, and shorter analysis time. These advantages, however, are often claimed without providing any experimental evidence, or based on rather uncritical comparisons of limited sets of arbitrarily selected separation results. Therefore, the performance characteristics of non-aqueous vs. aqueous CZE certainly deserve closer scrutiny. The primary intention of Part II of this review is to give a critical survey of the literature on non-aqueous capillary electrophoresis (NACE) that has emerged over the last five years. Emphasis is mainly placed on those studies that are concerned with the aspects of plate height, plate number, and the crucial mechanisms contributing to zone broadening, both in organic and aqueous conditions. To facilitate a deeper understanding, this treatment covers also the theoretical fundamentals of peak dispersion phenomena arising from wall adsorption; concentration overload (electromigration dispersion); longitudinal diffusion; and thermal gradients. Theoretically achievable plate numbers are discussed, both under limiting (at zero ionic strength) and application-relevant conditions (at finite ionic strength). In addition, the impact of the superimposed electroosmotic flow contributions to overall CZE performance is addressed, both for aqueous and non-aqueous media. It was concluded that for peak dispersion due to wall adsorption and due to concentration overload (electromigration dispersion, leading to peak triangulation) no general conjunction with the solvent can be deduced. This is in contrast to longitudinal diffusion: the

  20. Human Rehabilitation Techniques. Disability Analyses: Motor Disabilities. Volume II, Part A.

    Science.gov (United States)

    Sigelman, C.; And Others

    Volume II, Section A of a six-volume final report (which covers the findings of a research project on policy and technology related to rehabilitation of disabled individuals) presents a review of literature on three types of motor disabilities--stroke, spinal cord injury, and cerebral palsy. Individual chapters on each disability cover the…

  1. GUIDE FOR TEACHING ENGLISH AS A SECOND LANGUAGE TO ELEMENTARY SCHOOL PUPILS. LEVEL II, PART 1.

    Science.gov (United States)

    WILSON, ROBERT; AND OTHERS

    THE 55 AUDIO-LINGUAL LESSON UNITS OF "TEACHING ENGLISH EARLY" ARE DESIGNED AS A GUIDE FOR THE TEACHER OF ELEMENTARY GRADE CHILDREN WHO HAVE REACHED LEVEL II IN ENGLISH AS A SECOND LANGUAGE. AIMED PRIMARILY AT THE SPANISH-SPEAKING (MEXICAN-AMERICAN) CHILD, THIS PRE-READING MATERIAL MAY BE USED WITH OTHER LANGUAGE BACKGROUNDS. (SEE THE FINAL REPORT…

  2. 40 CFR Appendix II to Part 1068 - Emission-Related Parameters and Specifications

    Science.gov (United States)

    2010-07-01

    ... dimension. 4. Camshaft timing. a. Valve opening—intake exhaust (degrees from top-dead center or bottom-dead center). b. Valve closing—intake exhaust (degrees from top-dead center or bottom-dead center). c. Valve... bottom-dead center). II. Intake Air System. 1. Roots blower/supercharger/turbocharger calibration. 2...

  3. Studies on the sediments of Vembanad Lake, Kerala state: Part II - Distribution of phosphorus

    Digital Repository Service at National Institute of Oceanography (India)

    Murty, P.S.N.; Veerayya, M.

    in the estuarine region has been attributed to several factors. The impoverishment of Mn and Co can be due to (i) desorption of these elements from the river borne detritus on coming into contact with saline waters, (ii) dredging operations which may lead...

  4. Water mite species of the genus Hydrodroma Koch (Acari: Hydrachnidia, Hydrodromidae) from Australia. Part II.

    NARCIS (Netherlands)

    Pesic, V.; Smit, H.

    2007-01-01

    Abstract: Two new water mite species of the genus Hydrodroma Koch (Acari: Hydrachnidia, Hydrodromidae), characterized by single or absence of swimming setae on II-L-5, are reported from Australia: Hydrodroma wilesi sp. nov. and H. cooki sp. nov. New information is provided for H. tonapii Cook from

  5. AUTOMOTIVE DIESEL MAINTENANCE 2. UNIT XV, UNDERSTANDING DC GENERATOR PRINCIPLES (PART II).

    Science.gov (United States)

    Human Engineering Inst., Cleveland, OH.

    THIS MODULE OF A 25-MODULE COURSE IS DESIGNED TO DEVELOP AN UNDERSTANDING OF MAINTENANCE PROCEDURES FOR DIRECT CURRENT GENERATORS USED ON DIESEL POWERED EQUIPMENT. TOPICS ARE SPECIAL GENERATOR CIRCUITS, GENERATOR TESTING, AND GENERATOR POLARITY. THE MODULE CONSISTS OF A SELF-INSTRUCTIONAL PROGRAMED TRAINING FILM "DC GENERATORS II--GENERATOR…

  6. Human Rehabilitation Techniques. Disability Analyses: Behavioral Disabilities. Volume II, Part B.

    Science.gov (United States)

    Sigelman, C.; And Others

    Volume II, Section B of a six-volume final report (which covers the findings of a research project on policy and technology related to rehabilitation of disabled individuals) presents a review of literature on three types of behavior disabilities--epilepsy, mental retardation, and schizophrenia. Individual chapters on each disability cover the…

  7. Essential features of Chiari II malformation in MR imaging : an interobserver reliability study-part 1

    NARCIS (Netherlands)

    Geerdink, Niels; van der Vliet, Ton; Rotteveel, Jan J.; Feuth, Ton; Roeleveld, Nel; Mullaart, Reinier A.

    Brain MR imaging is essential in the assessment of Chiari II malformation in clinical and research settings concerning spina bifida. However, the interpretation of morphological features of the malformation on MR images may not always be straightforward. In an attempt to select those features that

  8. Essential features of Chiari II malformation in MR imaging: an interobserver reliability study--part 1.

    NARCIS (Netherlands)

    Geerdink, N.; Vliet, T. van der; Rotteveel, J.J.; Feuth, T.; Roeleveld, N.; Mullaart, R.A.

    2012-01-01

    PURPOSE: Brain MR imaging is essential in the assessment of Chiari II malformation in clinical and research settings concerning spina bifida. However, the interpretation of morphological features of the malformation on MR images may not always be straightforward. In an attempt to select those

  9. Two Causes of Underachievement--The Scapegoat Phenomenon and the Peter Pan Syndrome. Part II.

    Science.gov (United States)

    Grau, Phyllis Nelson

    1986-01-01

    Two profiles of underachievement are described: the Peter Pan Syndrome, characterized by irresponsibility, anxiety, loneliness, sex role conflict, and narcissism, and the scapegoating phenomenon, in which children acquire negative self-images from victimization experiences. Prognoses and recommendations for each are offered. (Author/CL)

  10. Parallel graph reduction for divide-and-conquer applications -- Part II: program performance

    NARCIS (Netherlands)

    Hartel, Pieter H.; Vree, Willem G.

    1988-01-01

    An extensible machine architecture is devised to efficiently support a parallel reduction model of computation. The organisation of the machine is designed to match the behaviour of the application programs. A pilot implementation of the architecture is used to obtain an execution profile of the

  11. A study of flame spread in engineered cardboard fuelbeds: Part II: Scaling law approach

    Science.gov (United States)

    Brittany A. Adam; Nelson K. Akafuah; Mark Finney; Jason Forthofer; Kozo Saito

    2013-01-01

    In this second part of a two part exploration of dynamic behavior observed in wildland fires, time scales differentiating convective and radiative heat transfer is further explored. Scaling laws for the two different types of heat transfer considered: Radiation-driven fire spread, and convection-driven fire spread, which can both occur during wildland fires. A new...

  12. Empirical Psycho-Aesthetics and Her Sisters: Substantive and Methodological Issues--Part II

    Science.gov (United States)

    Konecni, Vladimir J.

    2013-01-01

    Empirical psycho-aesthetics is approached in this two-part article from two directions. Part I, which appeared in the Winter 2012 issue of "JAE," addressed definitional and organizational issues, including the field's origins, its relation to "sister" disciplines (experimental philosophy, cognitive neuroscience of art, and neuroaesthetics), and…

  13. Intraosseous carcinoma of the jaws: A clinicopathologic review. part II: Odontogenic carcinomas

    NARCIS (Netherlands)

    Woolgar, J.A.; Triantafyllou, A.; Ferlito, A.; Devaney, K.O.; Lewis Jr., J.S.; Rinaldo, A.; Slootweg, P.J.; Barnes, L.

    2013-01-01

    This is the second of a 3-part review of the clinicopathologic features of intraosseous carcinoma of the jaws (IOCJ). This part deals with odontogenic carcinomas, rare entities that are difficult to evaluate because of changes in classification/nomenclature, lack of standardized diagnostic criteria,

  14. Green's function of an infinite slot printed between two homogeneous dielectrics - Part II: Uniform asymptotic solution

    NARCIS (Netherlands)

    Maci, S.; Neto, A.

    2004-01-01

    This second part of a two-paper sequence deals with the uniform asymptotic description of the Green's function of an infinite slot printed between two different homogeneous dielectric media. Starting from the magnetic current derived in Part I, the dyadic green's function is first formulated in

  15. Instrumentation: Photodiode Array Detectors in UV-VIS Spectroscopy. Part II.

    Science.gov (United States)

    Jones, Dianna G.

    1985-01-01

    A previous part (Analytical Chemistry; v57 n9 p1057A) discussed the theoretical aspects of diode ultraviolet-visual (UV-VIS) spectroscopy. This part describes the applications of diode arrays in analytical chemistry, also considering spectroelectrochemistry, high performance liquid chromatography (HPLC), HPLC data processing, stopped flow, and…

  16. REMOTE SENSING TOOLS ASSIST IN ENVIRONMENTAL FORENSICS PART II - DIGITAL TOOLS

    Science.gov (United States)

    This is part two of a two-part discussion, in which we will provide an overview of the use of GIS and GPS in environmental analysis and enforcement. GIS describes a system that manages, analyzes and displays geographic information. Environmental applications include anal...

  17. An Interpretative Review of Smokeless Tobacco Research in the United States: Part II.

    Science.gov (United States)

    Glover, Elbert D.; And Others

    1989-01-01

    Presents second part of two-part series reviewing the published literature of smokeless tobacco in the United States. Explores smokeless tobacco as a pharmacologically addicting substance, discusses educational interventions designed to prevent use or help users quit, and outlines areas of future research. (Author)

  18. Profiles of Major Suppliers to the Automotive Industry : Vol. 6. Foreign Automotive Parts and Components Suppliers.

    Science.gov (United States)

    1982-08-01

    This study summarizes extensive information collected over a two-year period (October 1978 to October 1980) on suppliers of parts and components, materials, and machine tools to the automotive industry in the United States. The objective of the study...

  19. Profiles of Major Suppliers to the Automotive Industry : Vol. 5. Multinational Automotive Parts and Components Suppliers

    Science.gov (United States)

    1982-08-01

    This study summarizes extensive information collected over a two-year period (October 1978 to October 1980) on suppliers of parts and components, materials, and machine tools to the automotive industry in the United States. The objective of the study...

  20. Metabolites profiling of Chrysanthemum pacificum Nakai parts using UPLC-PDA-MS coupled to chemometrics.

    Science.gov (United States)

    Farag, Nermeen F; Farag, Mohamed A; Abdelrahman, Enas H; Azzam, Shadia M; El-Kashoury, El-Sayeda A

    2015-01-01

    Methanol-soluble constituents from the flowers, non-flowering aerial parts and roots of Chrysanthemum pacificum Nakai were analysed via high resolution UPLC-PDA-qTOF-MS followed by chemometrics. Forty-seven chromatographic peaks belonging to various metabolite classes were detected. Most metabolite classes showed qualitative and quantitative differences across parts, with luteolin conjugates being mostly enriched in flowers whereas non-flowering aerial parts contained mostly quercetin and methoxylated flavone conjugates. Root sample ranked the lowest for all flavones and dicaffeoylquinic acids. In contrast, 1,5-di-caffeoylquinic acid levels were found at high levels in flowers and aerial parts reaching 3145 and 1390 μg/g, respectively, suggesting that C. pacificum could serve as a natural resource of this well-recognised anti-hepatotoxic phenolic. Principal component analysis was further used for organs classification in an untargeted manner. This study provides the first map of secondary metabolites distribution in C. pacificum Nakai organs.

  1. In vitro performance of Class I and II composite restorations: a literature review on nondestructive laboratory trials--part I.

    Science.gov (United States)

    Dietschi, D; Argente, A; Krejci, I; Mandikos, M

    2013-01-01

    Posterior adhesive restorations are a basic procedure in general dental practices, but their application remains poorly standardized as a result of the number of available options. An abundant number of study hypotheses corresponding to almost unlimited combinations of preparation techniques, adhesive procedures, restorative options, and materials have been described in the literature and submitted to various evaluation protocols. A literature review was thus conducted on adhesive Class I and II restorations and nondestructive in vitro tests using the PubMed/Medline database for the 1995-2010 period. The first part of this review discusses the selected literature related to photoelasticity, finite element analysis (FEM), and microleakage protocols. Based on the aforementioned evaluation methods, the following parameters proved influential: cavity dimensions and design, activation mode (light or chemical), type of curing light, layering technique, and composite structure or physical characteristics. Photoelasticity has various limitations and has been largely (and advantageously) replaced by the FEM technique. The results of microleakage studies proved to be highly inconsistent, and the further use of this technique should be strictly limited. Other study protocols for adhesive Class II restorations were also reviewed and will be addressed in part II of this article, together with a tentative relevance hierarchy of selected in vitro methods.

  2. Cancer concepts and principles: primer for the interventional oncologist-part II.

    Science.gov (United States)

    Hickey, Ryan; Vouche, Michael; Sze, Daniel Y; Hohlastos, Elias; Collins, Jeremy; Schirmang, Todd; Memon, Khairuddin; Ryu, Robert K; Sato, Kent; Chen, Richard; Gupta, Ramona; Resnick, Scott; Carr, James; Chrisman, Howard B; Nemcek, Albert A; Vogelzang, Robert L; Lewandowski, Robert J; Salem, Riad

    2013-08-01

    This is the second of a two-part overview of the fundamentals of oncology for interventional radiologists. The first part focused on clinical trials, basic statistics, assessment of response, and overall concepts in oncology. This second part aims to review the methods of tumor characterization; principles of the oncology specialties, including medical, surgical, radiation, and interventional oncology; and current treatment paradigms for the most common cancers encountered in interventional oncology, along with the levels of evidence that guide these treatments. Copyright © 2013 SIR. Published by Elsevier Inc. All rights reserved.

  3. Cross-reactivity profiles of hybrid capture II, cobas, and APTIMA human papillomavirus assays

    DEFF Research Database (Denmark)

    Preisler, Sarah Nørgaard; Rebolj, Matejka; Ejegod, Ditte Møller

    2016-01-01

    Background High-risk Human Papillomavirus (HPV) testing is replacing cytology in cervical cancer screening as it is more sensitive for preinvasive cervical lesions. However, the bottleneck of HPV testing is the many false positive test results (positive tests without cervical lesions). Here, we...... evaluated to what extent these can be explained by cross-reactivity, i.e. positive test results without evidence of high-risk HPV genotypes. The patterns of cross-reactivity have been thoroughly studied for hybrid capture II (HC2) but not yet for newer HPV assays although the manufacturers claimed...

  4. Nine-year change in statistical design, profile, and success rates of Phase II oncology trials.

    Science.gov (United States)

    Ivanova, Anastasia; Paul, Barry; Marchenko, Olga; Song, Guochen; Patel, Neerali; Moschos, Stergios J

    2016-01-01

    We investigated nine-year trends in statistical design and other features of Phase II oncology clinical trials published in 2005, 2010, and 2014 in five leading oncology journals: Cancer, Clinical Cancer Research, Journal of Clinical Oncology, Annals of Oncology, and Lancet Oncology. The features analyzed included cancer type, multicenter vs. single-institution, statistical design, primary endpoint, number of treatment arms, number of patients per treatment arm, whether or not statistical methods were well described, whether the drug was found effective based on rigorous statistical testing of the null hypothesis, and whether the drug was recommended for future studies.

  5. Pre-requisites for the formation of unusual diffusion profiles in II-VI semiconductors

    CERN Document Server

    Wolf, H; Kronenberg, J; Wagner, F; ISOLDE Collaboration

    2010-01-01

    The diffusion of the impurities Cu, Ag, Au, and Na in CdTe and CdZnTe exhibits the unusual phenomenon of uphill diffusion if the diffusion of the impurity is performed under external Cd pressure at temperatures typically in the range 700-900 K. A model is proposed that describes these concentration profiles quantitatively and yields pre-requisites for the observation of uphill diffusion. If a metal layer is evaporated onto the implanted surface, the diffusion of the impurity is strongly affected by the generation of intrinsic defects at the metal-semiconductor interface. (C) 2010 WILEY-VCH Verlag GmbH \\& Co. KGaA, Weinheim

  6. Overexpression of the IGF-II/M6P receptor in mouse fibroblast cell lines differentially alters expression profiles of genes involved in Alzheimer's disease-related pathology.

    Directory of Open Access Journals (Sweden)

    Yanlin Wang

    Full Text Available Alzheimer's disease (AD is the most common type of senile dementia affecting elderly people. The processing of amyloid precursor protein (APP leading to the generation of β-amyloid (Aβ peptide contributes to neurodegeneration and development of AD pathology. The endocytic trafficking pathway, which comprises of the endosomes and lysosomes, acts as an important site for Aβ generation, and endocytic dysfunction has been linked to increased Aβ production and loss of neurons in AD brains. Since insulin-like growth factor-II (IGF-II receptor plays a critical role in the transport of lysosomal enzymes from the trans-Golgi network to endosomes, it is likely that the receptor may have a role in regulating Aβ metabolism in AD pathology. However, very little is known on how altered levels of the IGF-II receptor can influence the expression/function of various molecules involved in AD pathology. To address this issue, we evaluated the expression profiles of 87 selected genes related to AD pathology in mouse fibroblast MS cells that are deficient in murine IGF-II receptor and corresponding MS9II cells overexpressing ∼ 500 times the human IGF-II receptors. Our results reveal that an elevation in IGF-II receptor levels alters the expression profiles of a number of genes including APP as well as enzymes regulating Aβ production, degradation and clearance mechanisms. Additionally, it influences the expression of various lysosomal enzymes and protein kinases that are involved in Aβ toxicity. IGF-II receptor overexpression also alters expression of several genes involved in intracellular signalling as well as cholesterol metabolism, which play a critical role in AD pathology. The altered gene profiles observed in this study closely match with the corresponding protein levels, with a few exceptions. These results, taken together, suggest that an elevation in IGF-II receptor levels can influence the expression profiles of transcripts as well as proteins

  7. The flipped classroom for professional development: part II. making podcasts and videos.

    Science.gov (United States)

    Smith, Charlene M; McDonald, Katie

    2013-11-01

    As described in Part I, podcasts and videos are educational technologies used to flip the classroom. This column describes the technology options for creating podcasts and videos and offers tips on developing podcasts and videos. Copyright 2013, SLACK Incorporated.

  8. Transcriptome analysis reveals distinct gene expression profiles in astrocytoma grades II-IV.

    Science.gov (United States)

    Narsia, Nato; Ramagiri, Pradeep; Ehrmann, Jiri; Kolar, Zdenek

    2017-09-01

    Astrocytoma is the most prevalent form of primary brain cancer categorized into four histological grades by the World Health Organization. Investigation into individual grades of astrocytoma by previous studies has provided some insight into dysregulation of regulatory networks associated with increasing astrocytoma grades. However, further understanding of key mechanisms that distinguish different astrocytoma grades is required to facilitate targeted therapies. In this study, we utilized a large cohort of publicly available RNA sequencing data from patients with diffuse astrocytoma (grade II), anaplastic astrocytoma (grade III), primary glioblastoma (grade IV), secondary glioblastoma (grade IV), recurrent glioblastoma (grade IV), and normal brain samples to identify genetic similarities and differences between these grades using bioinformatics applications. Our analysis revealed a distinct gene expression pattern between grade II astrocytoma and grade IV glioblastoma (GBM). We also identified genes that were exclusively expressed in each of the astrocytoma grades. Furthermore, we identified known and novel genes involved in key pathways in our study. Gene set enrichment analysis revealed a distinct expression pattern of transcriptional regulators in primary GBM. Further investigation into molecular processes showed that the genes involved in cell proliferation and invasion were shared across all subtypes of astrocytoma. Also, the number of genes involved in metastasis, regulation of cell proliferation, and apoptosis increased with tumor grade. We confirmed existing findings and shed light on some important genes and molecular processes that will improve our understanding of glioma biology.

  9. Handedness preference and switching of peptide helices. Part II: Helices based on noncoded α-amino acids.

    Science.gov (United States)

    Crisma, Marco; De Zotti, Marta; Formaggio, Fernando; Peggion, Cristina; Moretto, Alessandro; Toniolo, Claudio

    2015-03-01

    In this second part of our review article on the preferred screw sense and interconversion of peptide helices, we discuss the most significant computational and experimental data published on helices formed by the most extensively investigated categories of noncoded α-amino acids. They are as follows: (i) N-alkylated Gly residues (peptoids), (ii) C(α) -alkylated α-amino acids, (iii) C(α,β) -sp(2) configurated α-amino acids, and (iv) combinations of residues of types (ii) and (iii). With confidence, the large body of interesting papers examined and classified in this editorial effort will stimulate the development of helical peptides in many diverse areas of biosciences and nanosciences. Copyright © 2015 European Peptide Society and John Wiley & Sons, Ltd.

  10. The far-ultraviolet main auroral emission at Jupiter – Part 2: Vertical emission profile

    Directory of Open Access Journals (Sweden)

    B. Bonfond

    2015-10-01

    Full Text Available The aurorae at Jupiter are made up of many different features associated with a variety of generation mechanisms. The main auroral emission, also known as the main oval, is the most prominent of them as it accounts for approximately half of the total power emitted by the aurorae in the ultraviolet range. The energy of the precipitating electrons is a crucial parameter to characterize the processes at play which give rise to these auroral emissions, and the altitude of the emissions directly depends on this energy. Here we make use of far-UV (FUV images acquired with the Advanced Camera for Surveys on board the Hubble Space Telescope and spectra acquired with the Space Telescope Imaging Spectrograph to measure the vertical profile of the main emissions. The altitude of the brightness peak as seen above the limb is ~ 400 km, which is significantly higher than the 250 km measured in the post-dusk sector by Galileo in the visible domain. However, a detailed analysis of the effect of hydrocarbon absorption, including both simulations and FUV spectral observations, indicates that FUV apparent vertical profiles should be considered with caution, as these observations are not incompatible with an emission peak located at 250 km. The analysis also calls for spectral observations to be carried out with an optimized geometry in order to remove observational ambiguities.

  11. National Environmental/Energy Workforce Assessment, Phase II, Post-Secondary Education Profile: Solid Waste.

    Science.gov (United States)

    National Field Research Center Inc., Iowa City, IA.

    Educational programs in solid waste management offered by 16 schools in 9 states were surveyed. These programs represent a sample, only, of the various programs available nationwide. Enrollment and graduate statistics are presented. Overall, 116 full-time and 124 part-time faculty were involved in the programs surveyed. Curricula and sources of…

  12. Mammalian Toxicity of Munition Compounds. Phase II. Effects of Multiple Doses. Part I. Trinitroglycerin

    Science.gov (United States)

    1976-02-25

    and degeneration and hemosiderosis . Some re- covery occurred despite zontinued dosing, before the 13th week. Mice fed 11 or 100 mg/kg/day for 3 weeks...addition, both the male and female rats fed TNG had hemosiderosis in the spleen and/or the liver. Feeding of 25% lactose did not cause any adverse signs, any...nephritls or mononuclear cell infiltration of the kidney. In addition, one female control had hemosiderosis in the spleen and iI mesinteric lymph node

  13. Project Monitor: Part II. Conservation in small business: an exploratory study. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Hammond, P Y

    1979-08-01

    Project Monitor examined the energy conservation attitude and behavior of small samples of small business owners/operators in Allegheny County, Pennsylvania, focusing on manufacturing concerns and retailers. Section I reports the findings on the energy conserving behavior of 92 smaller manufacturers and Section II identifies the factors which affect decision making concerning energy consuming activities by the owners/operators of 94 small retail establishments. In each, the impact of Project Pacesetter and of the coal strike and the general energy situation is considered. (MCW)

  14. Supuestos resueltos de contabilidad II. parte 2ª. curso 2013-2014

    OpenAIRE

    Osés García, Javier

    2013-01-01

    Este documento contiene ejercicios solucionados y comentados sobre los temas que componen el Plan Docente de la asignatura COMPTABILITAT II del Grau en Administració i Direcció d’Empreses que se imparte en la Facultat Economia i Empresa de la Universitat de Barcelona. Todos los ejercicios contenidos han aparecido en cursos anteriores al 2012-2013 en alguna de las pruebas de evaluación continuada o exámenes de evaluación final de la asignatura. Entendemos que esta publicación es una h...

  15. Transactive System: Part II: Analysis of Two Pilot Transactive Systems using Foundational Theory and Metrics

    Energy Technology Data Exchange (ETDEWEB)

    Lian, Jianming; Sun, Y; Kalsi, Karanjit; Widergren, Steven E.; Wu, Di; Ren, Huiying

    2018-01-24

    This document is the second of a two-part report. Part 1 reviewed several demonstrations of transactive control and compared them in terms of their payoff functions, control decisions, information privacy, and mathematical solution concepts. It was suggested in Part 1 that these four listed components should be adopted for meaningful comparison and design of future transactive systems. Part 2 proposes qualitative and quantitative metrics that will be needed to compare alternative transactive systems. It then uses the analysis and design principles from Part 1 while conducting more in-depth analysis of two transactive demonstrations: the American Electric Power (AEP) gridSMART Demonstration, which used a double –auction market mechanism, and a consensus method like that used in the Pacific Northwest Smart Grid Demonstration. Ultimately, metrics must be devised and used to meaningfully compare alternative transactive systems. One significant contribution of this report is an observation that the decision function used for thermostat control in the AEP gridSMART Demonstration has superior performance if its decision function is recast to more accurately reflect the power that will be used under for thermostatic control under alternative market outcomes.

  16. Arbitrary order 2D virtual elements for polygonal meshes: part II, inelastic problem

    Science.gov (United States)

    Artioli, E.; da Veiga, L. Beirão; Lovadina, C.; Sacco, E.

    2017-06-01

    The present paper is the second part of a twofold work, whose first part is reported in Artioli et al. (Comput Mech, 2017. doi: 10.1007/s00466-017-1404-5), concerning a newly developed Virtual element method (VEM) for 2D continuum problems. The first part of the work proposed a study for linear elastic problem. The aim of this part is to explore the features of the VEM formulation when material nonlinearity is considered, showing that the accuracy and easiness of implementation discovered in the analysis inherent to the first part of the work are still retained. Three different nonlinear constitutive laws are considered in the VEM formulation. In particular, the generalized viscoelastic model, the classical Mises plasticity with isotropic/kinematic hardening and a shape memory alloy constitutive law are implemented. The versatility with respect to all the considered nonlinear material constitutive laws is demonstrated through several numerical examples, also remarking that the proposed 2D VEM formulation can be straightforwardly implemented as in a standard nonlinear structural finite element method framework.

  17. Arbitrary order 2D virtual elements for polygonal meshes: part II, inelastic problem

    Science.gov (United States)

    Artioli, E.; Beirão da Veiga, L.; Lovadina, C.; Sacco, E.

    2017-10-01

    The present paper is the second part of a twofold work, whose first part is reported in Artioli et al. (Comput Mech, 2017. doi: 10.1007/s00466-017-1404-5), concerning a newly developed Virtual element method (VEM) for 2D continuum problems. The first part of the work proposed a study for linear elastic problem. The aim of this part is to explore the features of the VEM formulation when material nonlinearity is considered, showing that the accuracy and easiness of implementation discovered in the analysis inherent to the first part of the work are still retained. Three different nonlinear constitutive laws are considered in the VEM formulation. In particular, the generalized viscoelastic model, the classical Mises plasticity with isotropic/kinematic hardening and a shape memory alloy constitutive law are implemented. The versatility with respect to all the considered nonlinear material constitutive laws is demonstrated through several numerical examples, also remarking that the proposed 2D VEM formulation can be straightforwardly implemented as in a standard nonlinear structural finite element method framework.

  18. Controlled Nonlinear Stochastic Delay Equations: Part II: Approximations and Pipe-Flow Representations

    Energy Technology Data Exchange (ETDEWEB)

    Kushner, Harold J., E-mail: hjk@dam.brown.edu [Brown University, Applied Math (United States)

    2012-08-15

    This is the second part of a work dealing with key issues that have not been addressed in the modeling and numerical optimization of nonlinear stochastic delay systems. We consider new classes of models, such as those with nonlinear functions of several controls (such as products), each with is own delay, controlled random Poisson measure driving terms, admissions control with delayed retrials, and others. Part I was concerned with issues concerning the class of admissible controls and their approximations, since the classical definitions are inadequate for our models. This part is concerned with transportation equation representations and their approximations. Such representations of nonlinear stochastic delay models have been crucial in the development of numerical algorithms with much reduced memory and computational requirements. The representations for the new models are not obvious and are developed. They also provide a template for the adaptation of the Markov chain approximation numerical methods.

  19. A review of breast tomosynthesis. Part II. Image reconstruction, processing and analysis, and advanced applications

    Science.gov (United States)

    Sechopoulos, Ioannis

    2013-01-01

    Many important post-acquisition aspects of breast tomosynthesis imaging can impact its clinical performance. Chief among them is the reconstruction algorithm that generates the representation of the three-dimensional breast volume from the acquired projections. But even after reconstruction, additional processes, such as artifact reduction algorithms, computer aided detection and diagnosis, among others, can also impact the performance of breast tomosynthesis in the clinical realm. In this two part paper, a review of breast tomosynthesis research is performed, with an emphasis on its medical physics aspects. In the companion paper, the first part of this review, the research performed relevant to the image acquisition process is examined. This second part will review the research on the post-acquisition aspects, including reconstruction, image processing, and analysis, as well as the advanced applications being investigated for breast tomosynthesis. PMID:23298127

  20. Dental sequellae of alveolar clefts: utility of endosseous implants. Part II: clinical cases.

    Science.gov (United States)

    Samama, Yves; Tulasne, Jean-François

    2014-09-01

    This second part follows on from part 1 published in the previous issue of this journal. The aim of this publication is to offer teams specializing in the primary and secondary treatment of labio-alveolar-palatal clefts a prosthetic evaluation for more rational management of the dental sequellae of clefts for patients who, when they reach adulthood, often wish to improve their facial esthetics, in which the dental element plays an important part. The reorganization and restoration of the maxillary anterior teeth and their esthetic integration with respect to the face and lips would then be less of a problem for plastic surgeons and orthodontists. In this regard, the installation in this sector of implants, following ambitious bone surgery involving the sacrifice of the teeth of the medial nasal process in bilateral forms, is a protocol that could usefully be taken into account. Copyright © 2014 CEO. All rights reserved.

  1. Verification Test of the SURF and SURFplus Models in xRage: Part II

    Energy Technology Data Exchange (ETDEWEB)

    Menikoff, Ralph [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-06-20

    The previous study used an underdriven detonation wave (steady ZND reaction zone profile followed by a scale invariant rarefaction wave) for PBX 9502 as a validation test of the implementation of the SURF and SURFplus models in the xRage code. Even with a fairly fine uniform mesh (12,800 cells for 100mm) the detonation wave profile had limited resolution due to the thin reaction zone width (0.18mm) for the fast SURF burn rate. Here we study the effect of finer resolution by comparing results of simulations with cell sizes of 8, 2 and 1 μm, which corresponds to 25, 100 and 200 points within the reaction zone. With finer resolution the lead shock pressure is closer to the von Neumann spike pressure, and there is less noise in the rarefaction wave due to fluctuations within the reaction zone. As a result the average error decreases. The pointwise error is still dominated by the smearing the pressure kink in the vicinity of the sonic point which occurs at the end of the reaction zone.

  2. Evaluation and diagnosis of the hair loss patient: part II. Trichoscopic and laboratory evaluations.

    Science.gov (United States)

    Mubki, Thamer; Rudnicka, Lidia; Olszewska, Malgorzata; Shapiro, Jerry

    2014-09-01

    The use of trichoscopy for evaluating a number of hair and scalp disorders is gaining popularity. It is a simple and noninvasive in vivo tool for visualizing hair shafts and the scalp. Recently, alopecias have been classified according to their trichoscopic findings. The second part of this 2-part continuing medical education article reviews recent advances in this field and describes a systematic approach for using the differential diagnostic findings of trichoscopy in alopecia. Copyright © 2014 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.

  3. Interface fatigue crack propagation in sandwich X-joints – Part II: Finite element modeling

    DEFF Research Database (Denmark)

    Moslemian, Ramin; Berggreen, Christian

    2013-01-01

    The aim of the second and final part of this study is to simulate fatigue crack growth in the tested Sandwich Tear Test specimens, described in Part I, using the finite element method. To accelerate the simulation, a cycle jump method is utilized and implemented in the finite element routine....... The proposed method is based on conducting finite element analysis for a set of cycles to establish a trend line, extrapolating the trend line spanning many cycles, and use the extrapolated state as initial state for additional finite element simulations. The measured da/dN relations of the face/core interface...

  4. FROM ZERO-DIMENSIONAL TO 2-DIMENSIONAL CARBON NANOMATERIALS - part II: GRAPHENE

    Directory of Open Access Journals (Sweden)

    Cătălin IANCU

    2012-05-01

    Full Text Available As was presented in the first part of this review paper, lately, many theoretical and experimental studies have been carried out to develop one of the most interesting aspects of the science and nanotechnology which is called carbon-related nanomaterials. In this review paper are presented some of the most exciting and important developments in the synthesis, properties, and applications of low-dimensional carbon nanomaterials. In this part of the paper are presented the synthesis techniques used to produce the two-dimensional carbon nanomaterials (including graphene, and also the most important properties and potential applications of graphene.

  5. Extracranial tumor vascularity: determination by dynamic CT scanning. Part II. The unit approach

    Energy Technology Data Exchange (ETDEWEB)

    Som, P.M.; Lanzieri, C.F.; Sacher, M.; Lawson, W.; Biller, H.F.

    1985-02-01

    Twenty-eight patients had combined conventional drip infusion CT scans. The information about the anatomic location of the lesion, its configuration, its cross-sectional appearance, its vacularity (as determined by dynamic signature curves), and its clinical presentation were considered as a single overall unit. This diagnostic approach allowed a diagnosis to be made on virtually all of these enhancing lesions without resorting to either a digital venous imaging study or angiographic procedure. In 17 of these cases, such an invasive second procedure was performed either to confirm the CT impression as part of this study or as part of a therapeutic embolization procedure.

  6. Measurements of plasma profiles using a fast swept Langmuir probe in the VINETA-II magnetic reconnection experiment

    Science.gov (United States)

    Shesterikov, I.; Von Stechow, A.; Grulke, O.; Stenzel, R.; Klinger, T.

    2017-07-01

    A fast-swept Langmuir probe capable to be biased at a high voltages has been constructed and successfully operated at the VINETA-II magnetic reconnection experiment. The presented circuit has two main features beneficial for fast transient parameter changes in laboratory experiments as, e.g., plasma guns or magnetic reconnection: the implementation simplicity and the high voltage sweep range. This work presents its design and performance for time-dependent measurements of VINETA-II plasmas. The probe is biased with a sinusoidal voltage at a fixed frequency. Current - voltage characteristics are measured along the falling and rising slopes of the probe bias. The sweep frequency is fsweep= 150 kHz. The spatiotemporal evolution of radial plasma profiles is obtained by evaluation of the probe characteristics. The plasma density measurements agree with those derived from a microwave interferometer, demonstrating the reliability of the measurements. As a model plasma system, a plasma gun discharge with typical pulse times of 60 μ s is chosen.

  7. Troika's Portuguese Ministry of Justice Experiment, Part II: Continued positive results for civil enforcement actions in Troika's aftermath

    Directory of Open Access Journals (Sweden)

    Pedro Miguel Alves Ribeiro Correia

    2016-10-01

    Full Text Available This article constitutes part II of a series of studies on the impact of measures implemented by the Portuguese Ministry of Justice. Particularly, it addresses the results at the level of civil enforcement actions resulting from goals inscribed in the MoU signed between Portugal and the so called Troika (IMF/EC/ECB. The empirical study is now expanded to encompass the quantitative analysis of results achieved not only during the Troika’s period but during the post-Troika period as well. Results show a continued positive effect for civil enforcement actions in Troika's aftermath.

  8. Functional replacement of the Saccharomyces cerevisiae fatty acid synthase with a bacterial type II system allows flexible product profiles.

    Science.gov (United States)

    Fernandez-Moya, Ruben; Leber, Christopher; Cardenas, Javier; Da Silva, Nancy A

    2015-12-01

    The native yeast type I fatty acid synthase (FAS) is a complex, rigid enzyme, and challenging to engineer for the production of medium- or short-chain fatty acids. Introduction of a type II FAS is a promising alternative as it allows expression control for each discrete enzyme and the addition of heterologous thioesterases. In this study, the native Saccharomyces cerevisiae FAS was functionally replaced by the Escherichia coli type II FAS (eFAS) system. The E. coli acpS + acpP (together), fabB, fabD, fabG, fabH, fabI, fabZ, and tesA were expressed in individual S. cerevisiae strains, and enzyme activity was confirmed by in vitro activity assays. Eight genes were then integrated into the yeast genome, while tesA or an alternate thioesterase gene, fatB from Ricinus communis or TEII from Rattus novergicus, was expressed from a multi-copy plasmid. Native FAS activity was eliminated by knocking out the yeast FAS2 gene. The strains expressing only the eFAS as de novo fatty acid source grew without fatty acid supplementation demonstrating that this type II FAS is able to functionally replace the native yeast FAS. The engineered strain expressing the R. communis fatB thioesterase increased total fatty acid titer 1.7-fold and shifted the fatty acid profile towards C14 production, increasing it from <1% in the native strain to more than 30% of total fatty acids, and reducing C18 production from 39% to 8%. © 2015 Wiley Periodicals, Inc.

  9. Sintering of Multilayered Porous Structures: Part II – Experiments and Model Applications

    DEFF Research Database (Denmark)

    Ni, De Wei; Olevsky, Eugene; Esposito, Vincenzo

    2013-01-01

    Experimental analyses of shrinkage and distortion kinetics during sintering of bilayered porous and dense gadolinium-doped ceria Ce0.9Gd0.1O1.95d structures are carried out, and compared with the theoretical models developed in Part I of this work. A novel approach is developed for the determinat...

  10. Didactics of Biology. Selected Bibliography for 1982. Parts I and II. Information Bulletin.

    Science.gov (United States)

    Altmann, Antonin, Ed.; Lipertova, Paula, Ed.

    Selected articles on various aspects of biology teaching published in 1982 have been annotated in this two-part bibliography. Entries from 25 journals representing 12 countries are presented according to a topic area classification scheme listed in the table of contents. Countries represented include: Australia; Bulgaria; Czechoslovakia; Federal…

  11. Hip protectors: recommendations for conducting clinical trials--an international consensus statement (part II)

    DEFF Research Database (Denmark)

    Cameron, I D; Robinovitch, S; Birge, S

    2010-01-01

    While hip protectors are effective in some clinical trials, many, including all in community settings, have been unable to demonstrate effectiveness. This is due partly to differences in the design and analysis. The aim of this report is to develop recommendations for subsequent clinical research....

  12. [Liver fibrosis and cirrhosis--selected cytokines, growth factors and proteins. Part II].

    Science.gov (United States)

    Wirkowska, Agnieszka; Paczek, Leszek

    2011-01-01

    Fibrosis is characterized by balance disorders between syntesis and degradation ECM (Extracellular Matrix) by myofibroblasts. Activated by inflammation factor HSC cells transform in myofibroblasts. This changes are caused and assisted by number of mediators: cytokines, growth factors, kinases. All this stimulus we call fibrosis factors. This paper compose second part of object-article: Liver fibrosis and cirrhosis - causes.

  13. Numerical optimization of nitrogen application to rice. Part II. Field evaluations

    NARCIS (Netherlands)

    Berge, ten H.F.M.; Qinghua, S.; Zhiming, Z.; Rao, K.S.; Riethoven, J.J.M.; Zhong, X.

    1997-01-01

    The MANAGE-N model (Part I; Ten Berge et al., this issue) was tested by comparing predicted and measured final crop biomass production for 48 rice cultivars under application of 0, 30–40, 60–80 and 90 to 120 kg urea-N per ha at Cuttack, India, during seven consecutive wet seasons. The overall

  14. Elastic and Piezoelectric Properties of Boron Nitride Nanotube Composites. Part II; Finite Element Model

    Science.gov (United States)

    Kim, H. Alicia; Hardie, Robert; Yamakov, Vesselin; Park, Cheol

    2015-01-01

    This paper is the second part of a two-part series where the first part presents a molecular dynamics model of a single Boron Nitride Nanotube (BNNT) and this paper scales up to multiple BNNTs in a polymer matrix. This paper presents finite element (FE) models to investigate the effective elastic and piezoelectric properties of (BNNT) nanocomposites. The nanocomposites studied in this paper are thin films of polymer matrix with aligned co-planar BNNTs. The FE modelling approach provides a computationally efficient way to gain an understanding of the material properties. We examine several FE models to identify the most suitable models and investigate the effective properties with respect to the BNNT volume fraction and the number of nanotube walls. The FE models are constructed to represent aligned and randomly distributed BNNTs in a matrix of resin using 2D and 3D hollow and 3D filled cylinders. The homogenisation approach is employed to determine the overall elastic and piezoelectric constants for a range of volume fractions. These models are compared with an analytical model based on Mori-Tanaka formulation suitable for finite length cylindrical inclusions. The model applies to primarily single-wall BNNTs but is also extended to multi-wall BNNTs, for which preliminary results will be presented. Results from the Part 1 of this series can help to establish a constitutive relationship for input into the finite element model to enable the modeling of multiple BNNTs in a polymer matrix.

  15. Pathophysiology of immune-mediated demyelinating neuropathies--Part II: Neurology.

    Science.gov (United States)

    Franssen, Hessel; Straver, Dirk C G

    2014-01-01

    In the second part of this review we deal with the clinical aspects of immune-mediated demyelinating neuropathies. We describe the relationship between pathophysiology and symptoms and discuss the pathophysiology of specific disease entities, including Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuropathy, multifocal motor neuropathy, anti-myelin-associated glycoprotein neuropathy, and POEMS syndrome. Copyright © 2013 Wiley Periodicals, Inc.

  16. Quasi-homogeneous Critical Swirling Flows in Expanding pipes, Part II

    NARCIS (Netherlands)

    Fledderus, E.R.; van Groesen, Embrecht W.C.

    1996-01-01

    Time-independent swirling flows in rotationally symmetric pipes of constant and varying diameter are constructed using variational techniques. In Part I, by E. van Groesen, B. W. van de Fliert, and E. Fledderus (J. Math. Anal. Appl.,192(1995), 764-788.) critical flows in pipes of uniform

  17. Critiquing Teacher Preparation Research: An Overview of the Field, Part II

    Science.gov (United States)

    Cochran-Smith, Marilyn; Villegas, Ana Maria; Abrams, Linda; Chavez-Moreno, Laura; Mills, Tammy; Stern, Rebecca

    2015-01-01

    This is the second of a two-part article intended to offer teacher educators a cohesive overview of the sprawling and uneven field of research on teacher preparation by identifying, analyzing, and critiquing its major programs. The article discusses research on teacher preparation for the knowledge society and research on teacher preparation for…

  18. A history of the autonomic nervous system: part II: from Reil to the modern era.

    Science.gov (United States)

    Oakes, Peter C; Fisahn, Christian; Iwanaga, Joe; DiLorenzo, Daniel; Oskouian, Rod J; Tubbs, R Shane

    2016-12-01

    The history of the study of the autonomic nervous system is rich. At the beginning of the nineteenth century, scientists were beginning to more firmly grasp the reality of this part of the human nervous system. The evolution of our understanding of the autonomic nervous system has a rich history. Our current understanding is based on centuries of research and trial and error.

  19. Facilitating age diversity in organizations ‐ part II: managing perceptions and interactions

    NARCIS (Netherlands)

    Annet de Lange; Jürgen Deller; Beatrice van der Heijden; Guido Hertel

    2013-01-01

    Purpose ‐ Due to demographic changes in most industrialized countries, the average age of working people is continuously increasing, and the workforce is becoming more age-diverse. This review, together with the earlier JMP Special Issue "Facilitating age diversity in organizations ‐ part I:

  20. Facilitating age diversity in organizations – part II: managing perceptions and interactions

    NARCIS (Netherlands)

    Hertel, Guido; van der Heijden, Beatrice; de Lange, Annet H.; Deller, Jürgen

    2013-01-01

    Purpose – Due to demographic changes in most industrialized countries, the average age of working people is continuously increasing, and the workforce is becoming more age-diverse. This review, together with the earlier JMP Special Issue “Facilitating age diversity in organizations – part I:

  1. The Multi-Disciplinary Graduate Program in Educational Research. Final Report, Part II; Methodoloqical Trilogy.

    Science.gov (United States)

    Lazarsfeld, Paul F., Ed.

    Part two of a seven-section, final report on the Multi-Disciplinary Graduate Program in Educational Research, this document contains discussions of quantification and reason analysis. Quantification is presented as a language consisting of sentences (graphs and tables), words, (classificatory instruments), and grammar (rules for constructing and…

  2. Inequalities in South African health care: Part II. Setting the record ...

    African Journals Online (AJOL)

    While Part I of this article analysed the problem of structural inequalities in South African health care, this follow-up explores feasible and socially accountable principles as well as a policy strategy to equalise existing discrepancies and disparities. In addition, the prospects of equalising the disparities and discrepancies are ...

  3. The Concept of Time in Rehabilitation and Psychosocial Adaptation to Chronic Illness and Disability: Part II

    Science.gov (United States)

    Livneh, Hanoch

    2013-01-01

    The first part of this article focused on providing the reader with a general overview of the concept of time with special emphasis on understanding time's role in the structure of personality theories and their associated therapeutic approaches, as well as linking the discussion to the understanding of time in the context of psychosocial…

  4. EFSUMB Guidelines on Interventional Ultrasound (INVUS), Part II Diagnostic Ultrasound-Guided Interventional Procedures (Long Version)

    DEFF Research Database (Denmark)

    Sidhu, P. S.; Brabrand, K.; Cantisani, V.

    2015-01-01

    This is the second part of the series on interventional ultrasound guidelines of the Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB). It deals with the diagnostic interventional procedure. General points are discussed which are pertinent to all patients, followed by organ...

  5. Multi-scale narratives from an IA perspective: Part II Participatory local scenario development

    NARCIS (Netherlands)

    Kok, K.; Patel, M.; Rothman, D.; Quaranta, G.

    2006-01-01

    This paper builds on Part I, where three European and Mediterranean scenarios were introduced. Theses scenarios can be typified as qualitative, integrated narrative storylines that describe three possible directions of future change until 2030. The main purpose of the paper is to summarise the

  6. MATLAB-based Applications for Image Processing and Image Quality Assessment – Part II: Experimental Results

    Directory of Open Access Journals (Sweden)

    L. Krasula

    2012-04-01

    Full Text Available The paper provides an overview of some possible usage of the software described in the Part I. It contains the real examples of image quality improvement, distortion simulations, objective and subjective quality assessment and other ways of image processing that can be obtained by the individual applications.

  7. Base cation deposition in Europe - Part II. Acid neutralization capacity and contribution to forest nutrition

    NARCIS (Netherlands)

    Draaijers, G.P.J.; Leeuwen, E.P. van; Jong, P.G.H. de; Erisman, J.W.

    1997-01-01

    An assessment was made of the capacity of base cations to neutralize acid deposition and of the contribution of base cation deposition to forest nutrition in Europe. In large parts of southern Europe more than 50% of the potential acid deposition was found counteracted by deposition of non-sea salt

  8. Uni-directional waves over slowly varying bottom, part II: Deformation of travelling waves

    NARCIS (Netherlands)

    Pudjaprasetya, S.R.; Pudjaprasetya, S.R.; van Groesen, Embrecht W.C.

    1996-01-01

    A new Korteweg-de Vries type of equation for uni-directional waves over slowly varying bottom has been derived in Part I. The equation retains the Hamiltonian structure of the underlying complete set of equations for surface waves. For flat bottom it reduces to the standard Korteweg-de Vries

  9. Modern Standard Arabic: Intermediate Level, Part II, Lessons 14-30.

    Science.gov (United States)

    Abboud, Peter; And Others

    This volume, the second of three texts for use in intermediate Arabic language courses, contains 17 lessons, each consisting of five main parts. Lessons 11 to 20 do not provide English translations for full sentences. The remaining lessons (21-30) are devoted to developing reading skills and bringing the student to the advanced level. The lessons…

  10. Part II: Ab Initio and NMR Investigations into the Barrier to Internal ...

    African Journals Online (AJOL)

    A range of 2-oxo-2H-chromen-7-yl dimethylcarbamates were synthesized as described in part I of this publication, containing either an oxygen or sulphur α to the carbonyl or thiocarbonyl group of the amide moiety. Variable temperature and exchange spectroscopy NMR was performed on these compounds and the barrier ...

  11. Periodical Articles Dealing With the History of Advanced Mathematics--Part II

    Science.gov (United States)

    Reed, Cecil B.; Bidwell, James K.

    1976-01-01

    This is the second part of the bibliography published in the November 1976 issue, listing articles concerned with mathematics beyond that usually taught at the junior high level. Articles are listed concerning mathematical books, periodicals, mathematical societies, and mathematicians of ancient times through the 20th century; a miscellaneous…

  12. Use of modulated excitation signals in ultrasound. Part II: Design and performance for medical imaging applications

    DEFF Research Database (Denmark)

    Misaridis, Thanassis; Jensen, Jørgen Arendt

    2005-01-01

    For pt.I, see ibid., vol.52, no.2, p.177-91 (2005). In the first paper, the superiority of linear FM signals was shown in terms of signal-to-noise ratio and robustness to tissue attenuation. This second paper in the series of three papers on the application of coded excitation signals in medical....... The method is evaluated first for resolution performance and axial sidelobes through simulations with the program Field II. A coded excitation ultrasound imaging system based on a commercial scanner and a 4 MHz probe driven by coded sequences is presented and used for the clinical evaluation of the coded....... The paper also presents acquired images, using complementary Golay codes, that show the deleterious effects of attenuation on binary codes when processed with a matched filter, als- - o confirmed by the presented simulated images....

  13. Minimal intervention dentistry II: part 2. Management of caries and periodontal risks in general dental practice.

    Science.gov (United States)

    Lallam, C; Decup, F

    2014-02-01

    The long-term clinical management of caries and periodontal diseases requires a double approach, one that is concerned with both treatment and prevention. Dentists should recognise the risk factors and their likely triggers to be able to implement the right strategy as early as the diagnostic phase. This comprehensive assessment can easily be done in general practice. All it takes is to combine the patient's general information with the systemic and behavioural factors, and the clinical observations with the local factors. The resulting patient profile can thus effectively support treatment by providing the necessary explanations, advice or prescriptions in relation with the clinical procedures. The modifiable risk factors need to be monitored and the behaviours changed to stabilise or limit disease progression. The practitioner's active approach is meant to meet the patient's demand for preventive counselling.

  14. Search for novel histone deacetylase inhibitors. Part II: design and synthesis of novel isoferulic acid derivatives.

    Science.gov (United States)

    Lu, Wen; Wang, Fang; Zhang, Tao; Dong, Jinyun; Gao, Hongping; Su, Ping; Shi, Yaling; Zhang, Jie

    2014-05-01

    Previously, we described the discovery of potent ferulic acid-based histone deacetylase inhibitors (HDACIs) with halogeno-acetanilide as novel surface recognition moiety (SRM). In order to improve the affinity and activity of these HDACIs, twenty seven isoferulic acid derivatives were described herein. The majority of title compounds displayed potent HDAC inhibitory activity. In particular, IF5 and IF6 exhibited significant enzymatic inhibitory activities, with IC50 values of 0.73 ± 0.08 and 0.57 ± 0.16 μM, respectively. Furthermore, these compounds showed moderate antiproliferative activity against human cancer cells. Especially, IF6 displayed promising profile as an antitumor candidate with IC50 value of 3.91 ± 0.97 μM against HeLa cells. The results indicated that these isoferulic acid derivatives could serve as promising lead compounds for further optimization. Copyright © 2014 Elsevier Ltd. All rights reserved.

  15. Effects of Hofmeister salt series on gluten network formation: Part II. Anion series.

    Science.gov (United States)

    Tuhumury, H C D; Small, D M; Day, L

    2016-12-01

    Different anion salts from the Hofmeister series were used to investigate their effects on gluten network formation. The effects of these anion salts on the mixing properties of the dough and the rheological and chemical properties of gluten samples extracted from the dough with these respective salts were compared. The aim of this work was to determine how different anion salts influence the formation of the gluten structure during dough mixing. It was found that the Hofmeister anion salts affected the gluten network formation by interacting directly with specific amino acid residues that resulted in changes in gluten protein composition, specifically the percentage of the unextractable polymeric protein fractions (%UPP). These changes consequently led to remarkable differences in the mixing profiles and microstructural features of the dough, small deformation rheological properties of the gluten and a strain hardening behaviour of both dough and gluten samples. Copyright © 2016 Elsevier Ltd. All rights reserved.

  16. Vagus Nerve and Vagus Nerve Stimulation, a Comprehensive Review: Part II.

    Science.gov (United States)

    Yuan, Hsiangkuo; Silberstein, Stephen D

    2016-02-01

    The development of vagus nerve stimulation (VNS) began in the 19th century. Although it did not work well initially, it introduced the idea that led to many VNS-related animal studies for seizure control. In the 1990s, with the success of several early clinical trials, VNS was approved for the treatment of refractory epilepsy, and later for the refractory depression. To date, several novel electrical stimulating devices are being developed. New invasive devices are designed to automate the seizure control and for use in heart failure. Non-invasive transcutaneous devices, which stimulate auricular VN or carotid VN, are also undergoing clinical trials for treatment of epilepsy, pain, headache, and others. Noninvasive VNS (nVNS) exhibits greater safety profiles and seems similarly effective to their invasive counterpart. In this review, we discuss the history and development of VNS, as well as recent progress in invasive and nVNS. © 2015 American Headache Society.

  17. Practical recommendations for fertility preservation in women by the FertiPROTEKT network. Part II: fertility preservation techniques.

    Science.gov (United States)

    von Wolff, Michael; Germeyer, A; Liebenthron, J; Korell, M; Nawroth, F

    2018-01-01

    In addition to guidelines focusing on scientific evidence, practical recommendations on fertility preservation are also needed. A selective literature search was performed based on the clinical and scientific experience of the authors. This article (Part II) focuses on fertility preservation techniques. Part I, also published in this journal, provides information on disease prognosis, disease-specific therapy, and risks for loss of fertility. Ovarian stimulation including double stimulation and freezing of oocytes is the best-established therapy providing live birth chances in women good ovarian, if spontaneous conception is favoured and if preservation in women provides realistic chances of becoming pregnant. The choice of technique needs to be based on the time required, the woman's age, its risks and efficacy, and the individual preference of the patient.

  18. Ceramic materials for porcelain veneers: part II. Effect of material, shade, and thickness on translucency.

    Science.gov (United States)

    Barizon, Karine T L; Bergeron, Cathia; Vargas, Marcos A; Qian, Fang; Cobb, Deborah S; Gratton, David G; Geraldeli, Saulo

    2014-10-01

    Information regarding the differences in translucency among new ceramic systems is lacking. The purpose of this study was to compare the relative translucency of the different types of ceramic systems indicated for porcelain veneers and to evaluate the effect of shade and thickness on translucency. Disk specimens 13 mm in diameter and 0.7-mm thick were fabricated for the following 9 materials (n=5): VITA VM9, IPS Empress Esthetic, VITA PM9, Vitablocks Mark II, Kavo Everest G-Blank, IPS Empress CAD, IPS e.max CAD, IPS e.maxPress, and Lava Zirconia. VITA VM9 served as the positive control and Lava as the negative control. The disks were fabricated with the shade that corresponds to A1. For IPS e.maxPress, additional disks were made with different shades (BL2, BL4, A1, B1, O1, O2, V1, V2, V3), thickness (0.3 mm), and translucencies (high translucency, low translucency). Color coordinates (CIE L∗ a∗ b∗) were measured with a tristimulus colorimeter. The translucency parameter was calculated from the color difference of the material on a black versus a white background. One-way ANOVA, the post hoc Tukey honestly significant difference, and the Ryan-Einot-Gabriel-Welsch multiple range tests were used to analyze the data (α=.05). Statistically significant differences in the translucency parameter were found among porcelains (PPM9, Empress Esthetic>Empress CAD>Mark II, Everest, e.max CAD>e.max Press>Lava. Significant differences also were noted when different shades and thickness were compared (Pveneers present varying degrees of translucency. The thickness and shade of lithium disilicate ceramic affect its translucency. Shade affects translucency parameter less than thickness. Copyright © 2014 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  19. Profile Station Data Received from the British Hydrographic Office (November 1989 - December 1994) as Part of Data-Center-to-Data-Center Exchange (NODC Accession 9600017)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The accession contains Profile Station Data Received from the British Hydrographic Office collected between November 3, 1989 to December 26, 1994 as Part of...

  20. Temperature profiles from XBT casts from the BLUENOSE as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1976-04-20 (NODC Accession 7601066)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the BLUENOSE from 20 April 1976. Data were collected by the National Marine Fisheries Service (NMFS) as part...

  1. Temperature profiles from XBT casts from the BLUENOSE as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1977-08-17 (NODC Accession 7700691)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the BLUENOSE from 17 August 1977. Data were collected by the National Marine Fisheries Service (NMFS) as part...

  2. Temperature profiles from XBT casts from the BLUENOSE as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1977-06-14 (NODC Accession 7700521)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the BLUENOSE from 14 June 1977. Data were collected by the National Marine Fisheries Service (NMFS) as part...

  3. Temperature profiles from XBT casts from the BLUENOSE as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) project from 1976-03-25 (NODC Accession 7600884)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profiles were collected from XBT casts from the BLUENOSE from 25 March 1976. Data were collected by the National Marine Fisheries Service (NMFS) as part...

  4. Mixed ligand complexes of alkaline earth metals: Part XII. Mg(II, Ca(II, Sr(II and Ba(II complexes with 5-chlorosalicylaldehyde and salicylaldehyde or hydroxyaromatic ketones

    Directory of Open Access Journals (Sweden)

    MITHLESH AGRAWAL

    2002-04-01

    Full Text Available The reactions of alkaline earth metal chlorides with 5-chlorosalicylaldehyde and salicylaldehyde, 2-hydroxyacetophenone or 2-hydroxypropiophenone have been carried out in 1 : 1 : 1 mole ratio and the mixed ligand complexes of the type MLL’(H2O2 (where M = Mg(II, Ca(II, Sr(II and Ba(II, HL = 5-chlorosalicylaldehyde and HL’ = salicylaldehyde, 2-hydroxyacetophenone or 2-hydroxypropiophenone have been isolated. These complexes were characterized by TLC, conductance measurements, IR and 1H-NMR spectra.

  5. Clostridium botulinum Group II Isolate Phylogenomic Profiling Using Whole-Genome Sequence Data.

    Science.gov (United States)

    Weedmark, K A; Mabon, P; Hayden, K L; Lambert, D; Van Domselaar, G; Austin, J W; Corbett, C R

    2015-09-01

    Clostridium botulinum group II isolates (n = 163) from different geographic regions, outbreaks, and neurotoxin types and subtypes were characterized in silico using whole-genome sequence data. Two clusters representing a variety of botulinum neurotoxin (BoNT) types and subtypes were identified by multilocus sequence typing (MLST) and core single nucleotide polymorphism (SNP) analysis. While one cluster included BoNT/B4/F6/E9 and nontoxigenic members, the other comprised a wide variety of different BoNT/E subtype isolates and a nontoxigenic strain. In silico MLST and core SNP methods were consistent in terms of clade-level isolate classification; however, core SNP analysis showed higher resolution capability. Furthermore, core SNP analysis correctly distinguished isolates by outbreak and location. This study illustrated the utility of next-generation sequence-based typing approaches for isolate characterization and source attribution and identified discrete SNP loci and MLST alleles for isolate comparison. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

  6. Legal perceptions of forensic DNA profiling part I: a review of the legal literature.

    Science.gov (United States)

    Walsh, Simon J

    2005-12-01

    A forensic biologist is usually involved in the criminal justice system process somewhere between the police and the legal system, interacting in a practical context regularly and extensively with both. Forensic DNA research and development commonly involves initiatives that encroach into the neighbouring domains of the law enforcement or legal agencies. Despite this level of association, establishing meaningful cross-disciplinary communication and understanding within the justice system remains a challenge. As an example, there is an abundance of literature relating to forensic DNA profiling in legal and criminological periodicals. Such journals are perhaps outside the regular reading of forensic scientists and much of the legal discussion appears to go unnoticed. This situation is understandable; however, it is also undesirable particularly as forensic DNA developments are intertwined with significant changes in legislation and contentious issues of privacy, civil liberty and social justice. This paper attempts to address this shortcoming directly by summarising - from the viewpoint of a forensic scientist - some of the discussion in the legal literature. In particular the review focuses on discussion raising ideological and ethical concerns. Awareness of these views is of relevance to forensic science. It assists us to accurately place DNA evidence into context and to develop its role in achieving the broader criminal justice system objectives. Understanding the discussion also provides a way to enter the debate and communicate at an appropriate level the true potential of DNA to the legal community.

  7. Autonomy, consent and responsibility. Part II. Informed consent in medical care and in the law.

    Science.gov (United States)

    Mellado, J M

    Legal recognition of patient's rights aspired to change clinical relationship and medical lex artis. However, its implementation has been hampered by the scarcity of resources and the abundance of regulations. For several years, autonomy, consent, and responsibility have formed one of the backbones of the medical profession. However, they have sparked controversy and professional discomfort. In the first part of this article, we examine the conceptual and regulatory limitations of the principle of autonomy as the basis of informed consent. We approach the subject from philosophical, historical, legal, bioethical, deontological, and professional standpoints. In the second part, we cover the viability of informed consent in health care and its relationship with legal responsibility. Copyright © 2016 SERAM. Publicado por Elsevier España, S.L.U. All rights reserved.

  8. Imaging of juvenile spondyloarthritis. Part II: Ultrasonography and magnetic resonance imaging

    Directory of Open Access Journals (Sweden)

    Iwona Sudoł-Szopińska

    2017-09-01

    Full Text Available Juvenile spondyloarthropathies are mainly manifested by symptoms of peripheral arthritis and enthesitis. Early involvement of sacroiliac joints and spine is exceptionally rare in children; this usually happens in adulthood. Conventional radiographs visualize late inflammatory lesions. Early diagnosis is possible with the use of ultrasonography and magnetic resonance imaging. The first part of the article presented classifications and radiographic presentation of juvenile spondyloarthropathies. This part discusses changes seen on ultrasonography and magnetic resonance imaging. In patients with juvenile spondyloarthropathies, these examinations are conducted to diagnose inflammatory lesions in peripheral joints, tendon sheaths, tendons and bursae. Moreover, magnetic resonance also shows subchondral bone marrow edema, which is considered an early sign of inflammation. Ultrasonography and magnetic resonance imaging do not show specific lesions for any rheumatic disease. Nevertheless, they are conducted for early diagnosis, treatment monitoring and identifying complications. This article presents a spectrum of inflammatory changes and discusses the diagnostic value of ultrasonography and magnetic resonance imaging.

  9. Nanotechnology and its relationship to interventional radiology. Part II: Drug Delivery, Thermotherapy, and Vascular Intervention.

    Science.gov (United States)

    Power, Sarah; Slattery, Michael M; Lee, Michael J

    2011-08-01

    Nanotechnology can be defined as the design, creation, and manipulation of structures on the nanometer scale. This two-part review is intended to acquaint the interventionalist with the field of nanotechnology, and provide an overview of potential applications, while highlighting advances relevant to interventional radiology. Part 2 of the article concentrates on drug delivery, thermotherapy, and vascular intervention. In oncology, advances in drug delivery allow for improved efficacy, decreased toxicity, and greater potential for targeted therapy. Magnetic nanoparticles show potential for use in thermotherapy treatments of various tumours, and the effectiveness of radiofrequency ablation can be enhanced with nanoparticle chemotherapy agents. In vascular intervention, much work is focused on prevention of restenosis through developments in stent technology and systems for localised drug delivery to vessel walls. Further areas of interest include applications for thrombolysis and haemostasis.

  10. Global optimization of truss topology with discrete bar areas-Part II: Implementation and numerical results

    DEFF Research Database (Denmark)

    Achtziger, Wolfgang; Stolpe, Mathias

    2009-01-01

    bar areas. We consider here the difficult situation that the truss must be built from pre-produced bars with given areas. This paper together with Part I proposes an algorithmic framework for the calculation of a global optimizer of the underlying non-convex mixed integer design problem. In this paper......A classical problem within the field of structural optimization is to find the stiffest truss design subject to a given external static load and a bound on the total volume. The design variables describe the cross sectional areas of the bars. This class of problems is well-studied for continuous...... on the implementation details but also establish finite convergence of the branch-and-bound method. The algorithm is based on solving a sequence of continuous non-convex relaxations which can be formulated as quadratic programs according to the theory in Part I. The quadratic programs to be treated within the branch...

  11. Musculoskeletal disorders associated with HIV infection and AIDS. Part II: Non-infectious musculoskeletal conditions

    Energy Technology Data Exchange (ETDEWEB)

    Tehranzadeh, Jamshid [Department of Radiological Sciences, University of California, Irvine, CA (United States); Department of Radiological Sciences, Orange, CA (United States); Ter-Oganesyan, Ramon R. [College of Medicine, University of California, Irvine, CA (United States); Steinbach, Lynne S. [Department of Radiological Sciences, University of California, San Francisco (United States)

    2004-06-01

    This section of a two-part series on musculoskeletal disorders associated with HIV infection and AIDS reviews the non-infectious musculoskeletal conditions. In the first part, the infectious conditions were reviewed. The non-infectious conditions include polymyositis, drug-induced myopathy, myositis ossificans, adhesive capsulitis, avascular necrosis, bone marrow abnormalities, and hypertrophic osteoarthropathy. Inflammatory and reactive arthropathies are more prevalent in HIV-positive individuals, and a separate section is dedicated to these conditions, including Reiter's syndrome, psoriatic arthritis, HIV-associated arthritis, painful articular syndrome, and acute symmetric polyarthritis. Lastly, we include a discussion of HIV-related neoplastic processes that affect the musculoskeletal system, namely Kaposi's sarcoma and non-Hodgkin's lymphoma. (orig.)

  12. Simulación de un reactor-cambiador PARTE II

    OpenAIRE

    López Gabanes, Antonio; Molero Fernández, Jorge; Herraiz Zambudio, José A.; Villora Cano, Gloria; Bódalo Santoyo, Antonio

    1981-01-01

    Como aplicación al tratamiento sobre simulación de un reactorcambiador expuesto en la PARTE I, se realiza a continuación un ejemplo de diseño para un sistema de reacciones simultáneas altamente exotérmicas, empleando agua como agente de enfriamiento. En base al tratamiento teórico expuesto en la PARTE I, como aplicación y comprobación de cuanto allí quedó discutido, se ha realizado el diseño de un reactor catalítico para la producción de óxido de etileno, diseño en...

  13. Information theory in systems biology. Part II: protein-protein interaction and signaling networks.

    Science.gov (United States)

    Mousavian, Zaynab; Díaz, José; Masoudi-Nejad, Ali

    2016-03-01

    By the development of information theory in 1948 by Claude Shannon to address the problems in the field of data storage and data communication over (noisy) communication channel, it has been successfully applied in many other research areas such as bioinformatics and systems biology. In this manuscript, we attempt to review some of the existing literatures in systems biology, which are using the information theory measures in their calculations. As we have reviewed most of the existing information-theoretic methods in gene regulatory and metabolic networks in the first part of the review, so in the second part of our study, the application of information theory in other types of biological networks including protein-protein interaction and signaling networks will be surveyed. Copyright © 2015 Elsevier Ltd. All rights reserved.

  14. Advances in metabolome information retrieval: turning chemistry into biology. Part II: biological information recovery.

    Science.gov (United States)

    Tebani, Abdellah; Afonso, Carlos; Bekri, Soumeya

    2017-08-25

    This work reports the second part of a review intending to give the state of the art of major metabolic phenotyping strategies. It particularly deals with inherent advantages and limits regarding data analysis issues and biological information retrieval tools along with translational challenges. This Part starts with introducing the main data preprocessing strategies of the different metabolomics data. Then, it describes the main data analysis techniques including univariate and multivariate aspects. It also addresses the challenges related to metabolite annotation and characterization. Finally, functional analysis including pathway and network strategies are discussed. The last section of this review is devoted to practical considerations and current challenges and pathways to bring metabolomics into clinical environments.

  15. Nanotechnology and its relationship to interventional radiology. Part II: Drug Delivery, Thermotherapy, and Vascular Intervention.

    LENUS (Irish Health Repository)

    Power, Sarah

    2012-02-01

    Nanotechnology can be defined as the design, creation, and manipulation of structures on the nanometer scale. This two-part review is intended to acquaint the interventionalist with the field of nanotechnology, and provide an overview of potential applications, while highlighting advances relevant to interventional radiology. Part 2 of the article concentrates on drug delivery, thermotherapy, and vascular intervention. In oncology, advances in drug delivery allow for improved efficacy, decreased toxicity, and greater potential for targeted therapy. Magnetic nanoparticles show potential for use in thermotherapy treatments of various tumours, and the effectiveness of radiofrequency ablation can be enhanced with nanoparticle chemotherapy agents. In vascular intervention, much work is focused on prevention of restenosis through developments in stent technology and systems for localised drug delivery to vessel walls. Further areas of interest include applications for thrombolysis and haemostasis.

  16. Nanotechnology and its Relationship to Interventional Radiology. Part II: Drug Delivery, Thermotherapy, and Vascular Intervention.

    LENUS (Irish Health Repository)

    Power, Sarah

    2010-09-16

    Nanotechnology can be defined as the design, creation, and manipulation of structures on the nanometer scale. This two-part review is intended to acquaint the interventionalist with the field of nanotechnology, and provide an overview of potential applications, while highlighting advances relevant to interventional radiology. Part 2 of the article concentrates on drug delivery, thermotherapy, and vascular intervention. In oncology, advances in drug delivery allow for improved efficacy, decreased toxicity, and greater potential for targeted therapy. Magnetic nanoparticles show potential for use in thermotherapy treatments of various tumours, and the effectiveness of radiofrequency ablation can be enhanced with nanoparticle chemotherapy agents. In vascular intervention, much work is focused on prevention of restenosis through developments in stent technology and systems for localised drug delivery to vessel walls. Further areas of interest include applications for thrombolysis and haemostasis.

  17. Oral ulcers: clinical aspects. A tool for dermatologists. Part II. Chronic ulcers.

    Science.gov (United States)

    Muñoz-Corcuera, M; Esparza-Gómez, G; González-Moles, M A; Bascones-Martínez, A

    2009-06-01

    Oral ulcers are generally painful lesions that are related to various conditions developing within the oral cavity. They can be classified as acute or chronic according to their presentation and progression. Acute oral ulcers are be associated with conditions such as trauma, recurrent aphthous stomatitis, Behçet's disease, bacterial and viral infections, allergic reactions or adverse drug reactions. Chronic oral ulcers are associated with conditions such as oral lichen planus, pemphigus vulgaris, mucosal pemphigoid, lupus erythematosus, mycosis and some bacterial and parasitic diseases. The correct differential diagnosis is necessary to establish the appropriate treatment, taking into account all the possible causes of ulcers in the oral cavity. In this second part of this two-part review, chronic oral ulcers are reviewed.

  18. Interview-Based Qualitative Research in Emergency Care Part II: Data Collection, Analysis and Results Reporting

    OpenAIRE

    Ranney, Megan L.; Meisel, Zachary; Choo, Esther K.; Garro, Aris; Sasson, Comilla; Morrow, Kathleen

    2015-01-01

    Qualitative methods are increasingly being used in emergency care research. Rigorous qualitative methods can play a critical role in advancing the emergency care research agenda by allowing investigators to generate hypotheses, gain an in-depth understanding of health problems or specific populations, create expert consensus, and develop new intervention and dissemination strategies. In Part I of this two-article series, we provided an introduction to general principles of applied qualitative...

  19. Student nurse satisfaction levels with their courses: Part II--effects of academic variables.

    Science.gov (United States)

    El Ansari, Walid

    2002-02-01

    The degree of student satisfaction with their educational experiences is an important dimension in the assessment of institutional effectiveness. All nursing education teams are currently working on ways to improve the quality of their educational provision and increase the satisfaction of their students. This is the second of a two-part article on the factors that influence student satisfaction with their courses. Part I examined how the four demographic features of gender, disability, ethnicity and age influenced student satisfaction and their performance on nursing modules. This paper complements Part I by examining the effects of three educational factors (academic level of the module, mode of study, and the qualification aim) on the accomplishment and satisfaction levels of 460 students attending multidisciplinary health care modules at the School of Health Care, Oxford Brookes University, 2000/2001. The study found that in contrast to Level 1 students, Level 3 participants felt the need for modules to stimulate more interest, that module teams be more skilled and knowledgeable and that library resources be more abundant. The findings also suggested that part-time students required significantly more attention than full-time participants in terms of the need for smaller seminar groups that would facilitate contributions and decrease inhibitions among students, and were more concerned with the utility and relevance of their learning in relation to their chosen professions. Diploma participants had the highest satisfaction followed by the BA and then the BSc students. The findings raise issues which are of interest to academic staff and nursing students, and the implications for nurse education and curriculum design are discussed within the context of student nurse satisfaction and quality issues of learning and teaching in higher education. Copyright 2002, Elsevier Science Ltd. All rights reserved.

  20. Microgrids in Active Network Management-Part II:System Operation, Power Quality and Protection

    OpenAIRE

    Palizban, Omid; Kauhaniemi, Kimmo; Josep M. Guerrero

    2014-01-01

    The development of distribution networks for participation in active network management (ANM) and smart grids is introduced using the microgrid concept. In recent years, this issue has been researched and implemented by many experts. The second part of this paper describes those developed operational concepts of microgrids that have an impact on their participation in ANM and in the requirements for achieving targets. Power quality is the most challenging task in microgrids, especially when t...

  1. How to succeed in science: a concise guide for young biomedical scientists. Part II: making discoveries.

    Science.gov (United States)

    Yewdell, Jonathan W

    2008-06-01

    Making discoveries is the most important part of being a scientist, and also the most fun. Young scientists need to develop the experimental and mental skill sets that enable them to make discoveries, including how to recognize and exploit serendipity when it strikes. Here, I provide practical advice to young scientists on choosing a research topic, designing, performing and interpreting experiments and, last but not least, on maintaining your sanity in the process.

  2. Anti-Hypertensive Herbs and Their Mechanisms of Action: Part II

    Science.gov (United States)

    Anwar, M. Akhtar; Al Disi, Sara S.; Eid, Ali H.

    2016-01-01

    Traditional medicine has a history extending back to thousands of years, and during the intervening time, man has identified the healing properties of a very broad range of plants. Globally, the use of herbal therapies to treat and manage cardiovascular disease (CVD) is on the rise. This is the second part of our comprehensive review where we discuss the mechanisms of plants and herbs used for the treatment and management of high blood pressure. Similar to the first part, PubMed and ScienceDirect databases were utilized, and the following keywords and phrases were used as inclusion criteria: hypertension, high blood pressure, herbal medicine, complementary and alternative medicine, endothelial cells, nitric oxide (NO), vascular smooth muscle cell (VSMC) proliferation, hydrogen sulfide, nuclear factor kappa-B (NF-κB), oxidative stress, and epigenetics/epigenomics. Each of the aforementioned keywords was co-joined with plant or herb in question, and where possible with its constituent molecule(s). This part deals in particular with plants that are used, albeit less frequently, for the treatment and management of hypertension. We then discuss the interplay between herbs/prescription drugs and herbs/epigenetics in the context of this disease. The review then concludes with a recommendation for more rigorous, well-developed clinical trials to concretely determine the beneficial impact of herbs and plants on hypertension and a disease-free living. PMID:27014064

  3. Environmental stressors and cardio-metabolic disease: part II-mechanistic insights.

    Science.gov (United States)

    Münzel, Thomas; Sørensen, Mette; Gori, Tommaso; Schmidt, Frank P; Rao, Xiaoquan; Brook, Frank R; Chen, Lung Chi; Brook, Robert D; Rajagopalan, Sanjay

    2017-02-21

    Environmental factors can act as facilitators of chronic non-communicable diseases. Ambient noise and air pollution collectively outrank all other environmental risk factors in importance, contributing to over 75% of the disease and disability burden associated with known environmental risk factors. In the first part of this review, we discussed the global burden and epidemiologic evidence supporting the importance of these novel risk factors as facilitators of cardiometabolic disease. In this part, we will discuss pathophysiological mechanisms responsible for noise and air pollution-mediated effects. Akin to traditional cardiovascular risk factors, a considerable body of evidence suggests that these environmental agents induce low-grade inflammation, oxidative stress, vascular dysfunction, and autonomic nervous system imbalance, thereby facilitating the development of diseases such as hypertension and diabetes. Through their impact on traditional risk factors and via additional novel mechanisms, environmental risk factors may have much larger impact on cardiovascular events than currently appreciated. In the second part of this review, we discuss deficiencies and gaps in knowledge and opportunities for new research. © The Author 2016. Published by Oxford University Press on behalf of the European Society of Cardiology.

  4. The motion planning problem and exponential stabilization of a heavy chain. Part II

    Directory of Open Access Journals (Sweden)

    Piotr Grabowski

    2008-01-01

    Full Text Available This is the second part of paper [P. Grabowski, The motion planning problem and exponential stabilization of a heavy chain. Part I, to appear in International Journal of Control], where a model of a heavy chain system with a punctual load (tip mass in the form of a system of partial differential equations was interpreted as an abstract semigroup system and then analysed on a Hilbert state space. In particular, in [P. Grabowski, The motion planning problem and exponential stabilization of a heavy chain. Part I, to appear in International Journal of Control] we have formulated the problem of exponential stabilizability of a heavy chain in a given position. It was also shown that the exponential stability can be achieved by applying a stabilizer of the colocated-type. The proof used the method of Lyapunov functionals. In the present paper, we give other two proofs of the exponential stability, which provides an additional intrinsic insight into the exponential stabilizability mechanism. The first proof makes use of some spectral properties of the system. In the second proof, we employ some relationships between exponential stability and exact observability.

  5. PIO I-II tendencies case study. Part 1. Mathematical modeling

    Directory of Open Access Journals (Sweden)

    Adrian TOADER

    2010-03-01

    Full Text Available In the paper, a study is performed from the perspective of giving a method to reduce the conservatism of the well known PIO (Pilot-Induced Oscillation criteria in predicting the susceptibility of an aircraft to this very harmful phenomenon. There are three interacting components of a PIO – the pilot, the vehicle, and the trigger (in fact, the hazard. The study, conceived in two parts, aims to underline the importance of human pilot model involved in analysis. In this first part, it is shown, following classical sources, how the LQG theory of control and estimation is used to obtain a complex model of human pilot. The approach is based on the argument, experimentally proved, that the human behaves “optimally” in some sense, subject to his inherent psychophysical limitations. The validation of such model is accomplished based on the experimental model of a VTOL-type aircraft. Then, the procedure of inserting typical saturation nonlinearities in the open loop transfer function is presented. A second part of the paper will illustrate PIO tendencies evaluation by means of a grapho-analytic method.

  6. Part I: In-situ fluorometric quantification of microalgal neutral lipids. Part II: Thermal degradation behavior of investment casting polymer patterns

    Science.gov (United States)

    Zhao, Hongfang

    Research described in this dissertation covers two topics. Part-I is focused on in-situ determination of neutral lipid content of microalgae using a lipophilic fluorescent dye. The traditional Nile red stain-based method for detecting microalgal intracellular lipids is limited due to varying composition and thickness of rigid cell walls. In this study, the addition of dilute acid and heating of solution, were found to greatly enhance staining efficiency of Nile red for microalgal species evaluated. Oil-in-water (O/W) microemulsion stabilized by a non-ionic surfactant was employed as a pseudo-standard that mimics lipid-bearing microalgal cells suspended in water. The average neutral lipid contents determined were very close to the results obtained by traditional gravimetric method and solid phase extraction. Part II of the dissertation explores thermo-physico-chemical properties of polymeric pattern materials, including expanded polystyrene (EPS) foam, polyurethane foam, and epoxy stereolithography (SLA) patterns, that are used in investment casting. Density, elastic modulus, expansion coefficient, thermal degradation behavior, etc. were experimentally investigated for their effects on metal casting quality. The reduction in toxic hydrogen cyanide (HCN) generated during thermal decomposition of polyurethane pattern was achieved by increasing either oxidant level or residence time in heated zone. Thermal degradation kinetics of the pattern materials were examined with a thermogravimetric analysis and activation energies were determined by Kissinger and Flynn-Wall-Ozawa methods.

  7. Comparative Analysis of Secretome Profiles of Manganese(II)-Oxidizing Ascomycete Fungi

    Energy Technology Data Exchange (ETDEWEB)

    Zeiner, Carolyn A.; Purvine, Samuel O.; Zink, Erika M.; Paša-Tolić, Ljiljana; Chaput, Dominique L.; Haridas, Sajeet; Wu, Si; LaButti, Kurt; Grigoriev, Igor V.; Henrissat, Bernard; Santelli, Cara M.; Hansel, Colleen M.; Pöggeler, Stefanie

    2016-07-19

    Fungal secretomes contain a wide range of hydrolytic and oxidative enzymes, including cellulases, hemicellulases, pectinases, and lignin-degrading accessory enzymes, that synergistically drive litter decomposition in the environment. While secretome studies of model organisms such as Phanerochaete chrysosporium and Aspergillus species have greatly expanded our knowledge of these enzymes, few have extended secretome characterization to environmental isolates or conducted side-by-side comparisons of diverse species. Thus, the mechanisms of carbon degradation by many ubiquitous soil fungi remain poorly understood. Here we use a combination of LC-MS/MS, genomic, and bioinformatic analyses to characterize and compare the protein composition of the secretomes of four recently isolated, cosmopolitan, Mn(II)-oxidizing Ascomycetes (Alternaria alternata SRC1lrK2f, Stagonospora sp. SRC1lsM3a, Pyrenochaeta sp. DS3sAY3a, and Paraconiothyrium sporulosum AP3s5-JAC2a). We demonstrate that the organisms produce a rich yet functionally similar suite of extracellular enzymes, with species-specific differences in secretome composition arising from unique amino acid sequences rather than overall protein function. Furthermore, we identify not only a wide range of carbohydrate-active enzymes that can directly oxidize recalcitrant carbon, but also an impressive suite of redox-active accessory enzymes that suggests a role for Fenton-based hydroxyl radical formation in indirect, non-specific lignocellulose attack. Our findings highlight the diverse oxidative capacity of these environmental isolates and enhance our understanding of the role of filamentous Ascomycetes in carbon turnover in the environment.

  8. Interactions of pharmacokinetic profile of different parts from Ginkgo biloba extract in rats.

    Science.gov (United States)

    Guan, HanLiang; Qian, Dawei; Ren, Hao; Zhang, Wei; Nie, Hui; Shang, Erxing; Duan, Jinao

    2014-08-08

    Extracts from Ginkgo biloba L. leaves confer their therapeutic effects through the synergistic actions of flavonoid and terpenoid components, but some non-flavonoid and non-terpenoid components also exist in this extract. In the study of this paper, an investigation was carried out to compare the pharmacokinetic parameters of fourteen compounds to clarify the influences of non-flavonoid and non-terpenoid fraction (WEF) on the pharmacokinetics profile of the flavonoid fraction (FF) and the terpene lactone fraction (TLF) from Ginkgo biloba extracts. A selective and sensitive UPLC-MS/MS method was established to determine the plasma concentrations of the fourteen compounds to compare the pharmacokinetic parameters after orally administration of FF, TLF, FF-WEF, FF-TLF, TLF-WEF and FF-TLF-WEF with approximately the same dose. At different time points, the concentration of rutin (1), isoquercitrin (2), quercetin 3-O-[4-O-(-β-D-glucosyl)-α-L-rhamnoside] (3), ginkgolide C (4), bilobalide (5), quercitrin (6), ginkgolide B (7), ginkgolide A (8), luteolin (9), quercetin (10), apigenin (11), kaempferol (12), isorhamnetin (13), genkwanin (14) in rat plasma were determined and main pharmacokinetic parameters including T1/2, Tmax, Cmax and AUC were calculated using the DAS 3.2 software package. The statistical analysis was performed using the Student׳s t-test with PGinkgo biloba extracts could increase the absorption and improve the bioavailability of flavonoid glycosides but decrease the absorption and reduce the bioavailability of flavonoid aglycones. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  9. Information Extraction from Large-scale WSNs: Approaches and Research Issues Part II: Query-Based and Macroprogramming Approaches

    Directory of Open Access Journals (Sweden)

    Tessa DANIEL

    2008-07-01

    Full Text Available Regardless of the application domain and deployment scope, the ability to retrieve information is critical to the successful functioning of any wireless sensor network (WSN system. In general, information extraction procedures can be categorized into three main approaches: agent-based, query-based and macroprogramming led. Whilst query-based systems are the most popular, macroprogramming techniques provide a more general-purpose approach to distributed computation. Finally, the agent-based approaches tailor the information extraction mechanism to the type of information needed and the configuration of the network it needs to be extracted from. This suite of three papers (Part I-III offers an extensive survey of the literature in the area of WSN information extraction, covering in Part I and Part II the three main approaches above. Part III highlights the open research questions and issues faced by deployable WSN system designers and discusses the potential benefits of both in-network processing and complex querying for large scale wireless informational systems.

  10. Profile of the orthodontist practicing in the state of São Paulo - Part 1

    Directory of Open Access Journals (Sweden)

    Fabio Brandalise Rampon

    2012-12-01

    Full Text Available INTRODUCTION: Orthodontics is no different from other sciences to the extent that it is a field in constant evolution and development. Nowadays, given the availability of a wide range of materials and biomechanical resources, as well as the development of new diagnostic capabilities, new methods to manage orthodontic treatment have emerged. Furthermore, due to the proliferation of postgraduate programs, it is increasingly important to gain insight into the profile of these specialists and the resources they use. OBJECTIVE: Examine the profile of orthodontists practicing in the State of São Paulo. The questions were prepared to evaluate different aspects of orthodontic practice. METHODS: A questionnaire was sent to 2.414 specialists in Orthodontics and Dentofacial Orthopedics registered with the Regional Board of Dentistry of São Paulo State (CRO-SP. To assess the association between qualitative variables, the Chi-square association test was employed at 5% significance level. RESULTS: Five hundred ninety-three (24.65% questionnaires were completed and returned. The sample profile consisted of males (54.3%, aged between 41 and 50 (40.5%, who had been registered with the São Paulo Regional Board of Dentistry (CRO-SP for 6 to 10 years (29.3%. The three most widely mentioned cephalometric analyses were standard USP (71.5%, McNamara (59.2% and Ricketts (52.8%. CONCLUSIONS: Based on a statistical analysis of the data one can conclude that the Straight-Wire technique was used most often (74.5%, and this technique is associated with orthodontists who have been specialists for less than 10 years. Most people surveyed (52.4% routinely make use of functional orthopedic resources in their daily practice.INTRODUÇÃO: a Ortodontia, como toda ciência, é um campo em permanente evolução e desenvolvimento. No panorama atual, devido à oferta de diversos tipos de materiais e das opções biomecânicas existentes, além do desenvolvimento de novos recursos

  11. Antioxidant activities and phenolics profiling of different parts of Carica papaya by LCMS-MS.

    Science.gov (United States)

    Zunjar, V; Mammen, D; Trivedi, B M

    2015-01-01

    This article deals with the comparison of the antioxidant activity of aqueous extracts of various parts of Carica papaya L. The evaluation of total phenolic content and total flavonoid content revealed high antioxidant potential of the seeds and fruits. The free radical-scavenging potential of the aqueous extracts indicated the seeds to have better DPPH-scavenging activity than fruits. The results were augmented by the FRAP activity as well. The phenolics present in the extracts were separated and identified as 5-hydroxy feruloyl quinic acid, acetyl p-coumaryl quinic acid, quercetin-3-O-rhamnoside, syringic acid hexoside, 5-hydroxy caffeic quinic acid, peonidin-3-O-glucoside, sinapic acid-O-hexoside, cyaniding-3-O-glucose and methyl feruloyl glycoside by LCMS-MS technique.

  12. Preliminary list of deep borings in the United States Part II: Nebraska-Wyoming

    Science.gov (United States)

    Darton, Nelson Horatio

    1902-01-01

    The wells and borings reported in the paper are all more than 400 feet in depth. The information concerning them has been obtained partly from replies to circular letters sent to all parts of the United States an  to lack of knowledge on the part of correspondents, and to the incompleteness of published records, doubtless there are borings which have not been reported. In regions of oil and gas wells, where borings are numerous, the individual wells can not be listed here, but representative wells are given. References to logs or records of the wells, or extended descriptions of them, are given in footnotes, and after the list of wells in each State there is added a list of the principal publications relating to deep borings in that state.The bearing of the information given in the columns of the lists probably is apparent, unless, perhaps, in the one headed "Height to which the water rises." In this column an entry such as "-45" indicates that the water rises to within 45 feet of the surface; "+45" indicates that it is a flowing well and has sufficient head to raise the water 45 feet above the surface in an open pipe 45 feet or more in height. The yield in gallons per minute usually is estimated. Depths and diameters often have been reported from memory, and different sources of publication sometimes give different figures. Most wells which are not stated to be "for oil," "for gas," "brine," "abandoned," etc., in the remarks column, or "not any" in the yield column, generally afford more or less water. Many of the gas and oil wells, active or abandoned, yield salt water.

  13. Review on health effects related to mobile phones. Part II: results and conclusions.

    Science.gov (United States)

    Moussa, Mayada M R

    2011-01-01

    Part 1 of this review was published in the Journal of Egyptian Association of Public Health 2010; 85(5, 6):337-345. It included the introduction and methodology. It was based on reviewing the literature published in the last 10 years (2000-2010). Searches were made electronically through various search engines and health-related databases, and manually through journals, reports, and conference proceedings. The references used in the introduction of part 1 were mainly WHO reports, textbooks, and nonserial publications. In part 2, the literature published in 2011 was added to the yield and the results and conclusions are based on the updated search. In this literature search, 69 research articles (epidemiologic, experimental, cellular, and animal studies), 17 systemic or meta-analysis review studies, and four reports were included. The evidence presented in these peer-reviewed publications did not provide a consistent pattern that exposure to mobile phones is detrimental to health. Only studies associating mobile phone use during driving with road traffic accidents and those investigating electromagnetic interference with personal or hospital medical electronic devices showed consistent results. Regarding children, there are currently little data on cell phone use and health effects, including the risk of cancer. Further experimental and epidemiologic studies are needed to seek explanations for the controversies in studies on mobile phones so far. These studies should apply sound methodology for exposure assessment of mobile phone radiation and should focus on the effects of long-term use (more than 10 years). Cohort studies, in particular, should be established to investigate the long-term effects of mobile phone use on brain cancer as well as to investigate the possible health effects among children.

  14. Hybrid infrared scene projector (HIRSP): a high dynamic range infrared scene projector, part II

    Science.gov (United States)

    Cantey, Thomas M.; Bowden, Mark; Cosby, David; Ballard, Gary

    2008-04-01

    This paper is a continuation of the merging of two dynamic infrared scene projector technologies to provide a unique and innovative solution for the simulation of high dynamic temperature ranges for testing infrared imaging sensors. This paper will present some of the challenges and performance issues encountered in implementing this unique projector system into a Hardware-in-the-Loop (HWIL) simulation facility. The projection system combines the technologies of a Honeywell BRITE II extended voltage range emissive resistor array device and an optically scanned laser diode array projector (LDAP). The high apparent temperature simulations are produced from the luminescent infrared radiation emitted by the high power laser diodes. The hybrid infrared projector system is being integrated into an existing HWIL simulation facility and is used to provide real-world high radiance imagery to an imaging infrared unit under test. The performance and operation of the projector is presented demonstrating the merit and success of the hybrid approach. The high dynamic range capability simulates a 250 Kelvin apparent background temperature to 850 Kelvin maximum apparent temperature signatures. This is a large increase in radiance projection over current infrared scene projection capabilities.

  15. Model-Based Assessment of Alternative Study Designs in Pediatric Trials. Part II: Bayesian Approaches.

    Science.gov (United States)

    Smania, G; Baiardi, P; Ceci, A; Cella, M; Magni, P

    2016-08-01

    This study presents a pharmacokinetic-pharmacodynamic based clinical trial simulation framework for evaluating the performance of a fixed-sample Bayesian design (BD) and two alternative Bayesian sequential designs (BSDs) (i.e., a non-hierarchical (NON-H) and a semi-hierarchical (SEMI-H) one). Prior information was elicited from adult trials and weighted based on the expected similarity of response to treatment between the pediatric and adult populations. Study designs were evaluated in terms of: type I and II errors, sample size per arm (SS), trial duration (TD), and estimate precision. No substantial differences were observed between NON-H and SEMI-H. BSDs require, on average, smaller SS and TD compared to the BD, which, on the other hand, guarantees higher estimate precision. When large differences between children and adults are expected, BSDs can return very large SS. Bayesian approaches appear to outperform their frequentist counterparts in the design of pediatric trials even when little weight is given to prior information from adults. © 2016 The Authors CPT: Pharmacometrics & Systems Pharmacology published by Wiley Periodicals, Inc. on behalf of American Society for Clinical Pharmacology and Therapeutics.

  16. Fuel cell-gas turbine hybrid system design part II: Dynamics and control

    Science.gov (United States)

    McLarty, Dustin; Brouwer, Jack; Samuelsen, Scott

    2014-05-01

    Fuel cell gas turbine hybrid systems have achieved ultra-high efficiency and ultra-low emissions at small scales, but have yet to demonstrate effective dynamic responsiveness or base-load cost savings. Fuel cell systems and hybrid prototypes have not utilized controls to address thermal cycling during load following operation, and have thus been relegated to the less valuable base-load and peak shaving power market. Additionally, pressurized hybrid topping cycles have exhibited increased stall/surge characteristics particularly during off-design operation. This paper evaluates additional control actuators with simple control methods capable of mitigating spatial temperature variation and stall/surge risk during load following operation of hybrid fuel cell systems. The novel use of detailed, spatially resolved, physical fuel cell and turbine models in an integrated system simulation enables the development and evaluation of these additional control methods. It is shown that the hybrid system can achieve greater dynamic response over a larger operating envelope than either individual sub-system; the fuel cell or gas turbine. Results indicate that a combined feed-forward, P-I and cascade control strategy is capable of handling moderate perturbations and achieving a 2:1 (MCFC) or 4:1 (SOFC) turndown ratio while retaining >65% fuel-to-electricity efficiency, while maintaining an acceptable stack temperature profile and stall/surge margin.

  17. Transferencia de calor en la colada continua de aceros. II parte. Enfriamiento secundario

    Directory of Open Access Journals (Sweden)

    Cicutti, C.

    1997-12-01

    Full Text Available Once the strand leaves the mold, the solidification of steel progresses due to the heat extracted in the secondary cooling zone of the continuous casting machine. In this zone, heat is extracted mainly by: the incidence of water from sprays, radiation to surroundings contact with rolls and run out water accumulated between rolls and strand. In this work, all these mechanisms are evaluated and, when it is possible, they are quantified. Methods which are usually employed to measure solidification profiles in the continuous casting machine are also reviewed. Finally, the incidence of secondary cooling on the quality of cast products is discussed.

    La solidificación del acero iniciada en el molde continúa en la zona de enfriamiento secundario de la máquina donde el calor es extraído, principalmente por la incidencia del agua de los rociadores, la radiación al medio ambiente, el contacto con los rodillos y el agua acumulada en ellos. En este trabajo se revisa cada uno de estos mecanismos determinando, en los casos en que es posible, valores cuantitativos de los mismos. Además, se analizan los distintos métodos empleados para medir el avance del espesor solidificado en la máquina de colada continua. Por último, se discute la incidencia del enfriamiento secundario en la calidad final de los productos colados.

  18. Thermomechanical Effects during Direct Chill and Electromagnetic Casting of Aluminum Alloys Part II : Numerical Simulation

    Science.gov (United States)

    Drezet, J.-M.; Rappaz, M.; Krähenbühl, Y.

    The prediction of the ingot deformation during direct chill (DC) and electromagnetic (EM) casting of aluminum alloy slabs would allow the optimization of the mold/inductor shape capable of producing flat ingots. The transient thermomechanical model presented here predicts the deformation and the temperature field evolution during DC/EM casting. Deformation in the solid is assumed to obey a viscoplastic law. The model is validated on the basis of the measurements presented in part I. It enables to predict the influence of casting parameters on butt curl and swell, rolling faces pull-in and residual stress state for DC and EM-cast ingots.

  19. OH-initiated oxidation of benzene - Part II. Influence of elevated NOx concentrations

    DEFF Research Database (Denmark)

    Klotz, B; Volkamer, R; Hurley, MD

    2002-01-01

    The present work represents a continuation of part I of this series of papers, in which we investigated the phenol yields in the OH-initiated oxidation of benzene under conditions of low to moderate concentrations of NOx, to elevated NOx levels. The products of the OH-initiated oxidation of benzene...... in 700 760 Torr of N-2/O-2 diluent at 297 +/- 4 K were investigated in 3 different photochemical reaction chambers. In situ spectroscopic techniques were employed for the detection of products, and the initial concentrations of benzene, NOx, and O-2 were widely varied (by factors of 6300, 1500, and 13...

  20. The evolution of the temperature field during cavity collapse in liquid nitromethane. Part II: Reactive case

    OpenAIRE

    Michael, Louisa; Nikiforakis, Nikolaos

    2017-01-01

    We study effect of cavity collapse in non-ideal explosives as a means of controlling their sensitivity. The main aim is to understand the origin of localised temperature peaks (hot spots) that play a leading order role at early ignition stages. Thus, we perform 2D and 3D numerical simulations of shock induced single gas-cavity collapse in nitromethane. Ignition is the result of a complex interplay between fluid dynamics and exothermic chemical reaction. In part I of this work we focused on th...

  1. Partíal amendments to the Restauro theory (II Value & values.

    Directory of Open Access Journals (Sweden)

    Alfonso Jiménez

    1998-04-01

    Full Text Available The architect Alfonso Jiménez presents the second part of the article published in the 4th edition of LOGGIA . Here he expands his opinions on the Restauro theory with reflections about industrial reproduction of artworks, the methodology used in interventions on masonry constructions and exclusions from the concepts of functionality and the artistic dimension of the intervention. Finally he analyses in depth the reach and influence of the concept of value in all its facets throughout the history of restoration

  2. Thermal performance analysis and measurements of the prototype cryomodules of European XFEL accelerator-Part II

    Science.gov (United States)

    Wang, X. L.; Barbanotti, S.; Eschke, J.; Jensch, K.; Klos, R.; Maschmann, W.; Petersen, B.; Sawlanski, O.

    2014-11-01

    Three accelerator prototype cryomodules (CMs) for the European XFEL have been produced, assembled and tested at DESY in a wide international collaboration. The heat load budget is a key element in the qualification of these CMs. We describe in this paper the measurements performed in the Cryomodule test bench (CMTB) to evaluate the thermal performances of the three prototype CMs. We present at first the methodology and instrumentation used for the measurements, then we analyse the main contributions to the heat loads at various temperature levels and finally we compare the measured values with the ones calculated and reported in the first part of this paper.

  3. Transonic Airfoil Flow Simulation. Part II: Inviscid-Viscous Coupling Scheme

    Directory of Open Access Journals (Sweden)

    Vladimir CARDOŞ

    2010-09-01

    Full Text Available A calculation method for the subsonic and transonic viscous flow over airfoil using the displacement surface concept is described. This modelling technique uses a finite volume method for the time-dependent Euler equations and laminar and turbulent boundary-layer integral methods. In additional special models for transition, laminar or turbulent separation bubbles and trailing edge treatment have been selected. However, the flow is limited to small parts of trailing edge-type separation. Comparisons with experimental data and other methods are shown.

  4. Modification of Concrete Damaged Plasticity model. Part II: Formulation and numerical tests

    Directory of Open Access Journals (Sweden)

    Kamińska Inez

    2017-01-01

    Full Text Available A refined model for elastoplastic damaged material is formulated based on the plastic potential introduced in Part I [1]. Considered model is an extension of Concrete Damaged Plasticity material implemented in Abaqus [2]. In the paper the stiffness tensor for elastoplastic damaged behaviour is derived. In order to validate the model, computations for the uniaxial tests are performed. Response of the model for various cases of parameter’s choice is shown and compared to the response of the CDP model.

  5. [Laboratory diagnostics of systemic autoimmune diseases. Part II: rheumatoid arthritis and vasculopathies].

    Science.gov (United States)

    Hartung, K; Seelig, H-P

    2007-05-01

    This is the second part in a series of articles on the laboratory diagnostics of rheumatic diseases. It addresses rheumatoid arthritis, systemic, anti-neutrophil cytoplasmatic antibody (ANCA) positive vasculitides and antiphospholipid-syndrome. The diagnostics of rheumatoid arthritis has been substantially improved by the recently introduced assay for antibodies against citrullinated peptides. In addition, a number of vasculitides can be differentiated by the presence of ANCA. Beta2-glycoprotein I antibodies and lupus anticoagulants are at present the most specific markers for antiphospholipid syndrome. Inflammatory activity can be monitored by determining the levels of acute phase proteins and erythrocyte sedimentation rate, but only in some situations by measuring immunoglobulins and interleukins.

  6. Managing the professional nurse. Part II. Applying management theory to the challenges.

    Science.gov (United States)

    McClure, M L

    1984-03-01

    In Part I of this article, the author reviewed the ideas of some of the major administrative thinkers over the past 30 years. Having set the stage with an overview of current thinking in the general area of management theory, the author here examines some of the specific challenges involved in managing the professional nurse. Often, these problems are unique and the management theorists offer only limited help. In other instances, management theory is directly relevant. The author addresses the following four broad categories that are unique to the profession of nursing: nursing as a female profession, professionalism and the lack of it, stress and burnout, and expectancy congruence.

  7. Nutrition of preterm infants with bronchopulmonary dysplasia after hospital discharge – Part II

    Directory of Open Access Journals (Sweden)

    Hercília Guimarães

    2014-01-01

    Full Text Available Preterm infants with bronchopulmonary dysplasia often present with severe growth failure at discharge from the neonatal intensive care unit. Catch-up growth accelerates after hospital discharge, nevertheless, feeding problems may need a specialized approach. Following the revision of the scientific literature on the most relevant aspects on nutrition of patients with bronchopulmonary dysplasia after hospital discharge in Part I, in this article the Authors present and discuss important issues such as catch up growth, swallow dysfunction, gastroesophageal reflux, and how to improve feeding competences.

  8. The year 2014 in the European Heart Journal--Cardiovascular Imaging: part II.

    Science.gov (United States)

    Gerber, Bernhard L; Edvardsen, Thor; Pierard, Luc A; Saraste, Antti; Knuuti, Juhani; Maurer, Gerald; Habib, Gilbert; Lancellotti, Patrizio

    2015-11-01

    The European Heart Journal-Cardiovascular Imaging, created in 2012, has become a reference for publishing multimodality cardiovascular imaging scientific and review papers. The impressive 2014 impact factor of 4.105 confirms the important position of our journal. In this part, we summarize the most important studies from the journal's third year, with specific emphasis on cardiomyopathies, congenital heart diseases, valvular heart diseases, and heart failure. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2015. For permissions please email: journals.permissions@oup.com.

  9. Resistance spot welding of galvanized steel: Part II. Mechanisms of spot weld nugget formation

    Science.gov (United States)

    Gedeon, S. A.; Eagar, T. W.

    1986-12-01

    Dynamic inspection monitoring of the weld current, voltage, resistance, electrode displacement, and force was performed in conjunction with a detailed study of the effects of material variations and weld process parameter modifications on resistance spot welding of coated and uncoated steels. In order to determine the mechanisms of weld nugget formation and growth, scanning electron microscopy photos were taken of the developing nugget. These physical changes were then related to the dynamic inspection curves and the welding current lobe. The effects of material variations and weld process modifications, the results of which were presented in Part I, can be explained through an understanding of these mechanisms.

  10. Frankincense Revisited, Part II: Volatiles in Rare Boswellia Species and Hybrids.

    Science.gov (United States)

    Niebler, Johannes; Eslamieh, Jason; Buettner, Andrea

    2016-05-01

    In this second part of the investigation of volatiles and semivolatiles in Boswellia gum resins, an additional five less common species were analyzed by (SPME-)GC/MS, namely B. ameero, B. elongata, B. neglecta, B. popoviana, and B. rivae. Moreover, the results of hybridization experiments are reported in combination with the volatile composition of their gum resins. Our study shows that B. sacra benefits from an intraspecific cross-pollination, as the resulting hybrid B. sacra var. supersacra has a far higher seed germination rate and viability. © 2016 Verlag Helvetica Chimica Acta AG, Zürich.

  11. Interaction of Zn(II) with hematite nanoparticles and microparticles: Part 2. ATR-FTIR and EXAFS study of the aqueous Zn(II)/oxalate/hematite ternary system.

    Science.gov (United States)

    Ha, Juyoung; Trainor, Thomas P; Farges, François; Brown, Gordon E

    2009-05-19

    Sorption of Zn(II) to hematite nanoparticles (HN) (av diam=10.5 nm) and microparticles (HM) (av diam=550 nm) was studied in the presence of oxalate anions (Ox2-(aq)) in aqueous solutions as a function of total Zn(II)(aq) to total Ox2-(aq) concentration ratio (R=[Zn(II)(aq)]tot/[Ox2-(aq)]tot) at pH 5.5. Zn(II) uptake is similar in extent for both the Zn(II)/Ox/HN and Zn(II)/Ox/HM ternary systems and the Zn(II)/HN binary system at [Zn(II)(aq)](tot)system than for the Zn(II)/Ox/HM ternary and the Zn(II)/HN and Zn(II)/HM binary systems at [Zn(II)(aq)]tot>4 mM. In contrast, Zn(II) uptake for the Zn(II)/HM binary system is a factor of 2 greater than that for the Zn(II)/Ox/HM and Zn(II)/Ox/HN ternary systems and the Zn(II)/HN binary system at [Zn(II)(aq)]totternary system at both R values examined (0.16 and 0.68), attenuated total reflectance Fourier transform infrared (ATR-FTIR) results are consistent with the presence of inner-sphere oxalate complexes and outer-sphere ZnOx(aq) complexes, and/or type A ternary complexes. In addition, extended X-ray absorption fine structure (EXAFS) spectroscopic results suggest that type A ternary surface complexes (i.e., >O2-Zn-Ox) are present. In the Zn(II)/Ox/HN ternary system at R=0.15, ATR-FTIR results indicate the presence of inner-sphere oxalate and outer-sphere ZnOx(aq) complexes; the EXAFS results provide no evidence for inner-sphere Zn(II) complexes or type A ternary complexes. In contrast, ATR-FTIR results for the Zn/Ox/HN sample with R = 0.68 are consistent with a ZnOx(s)-like surface precipitate and possibly type B ternary surface complexes (i.e., >O2-Ox-Zn). EXAFS results are also consistent with the presence of ZnOx(s)-like precipitates. We ascribe the observed increase of Zn(II)(aq) uptake in the Zn(II)/Ox/HN ternary system at [Zn(II)(aq)]tot>or=4 mM relative to the Zn(II)/Ox/HM ternary system to formation of a ZnOx(s)-like precipitate at the hematite nanoparticle/water interface.

  12. Structural theory and thermoeconomic diagnosis Part II: Application to an actual power plant

    Energy Technology Data Exchange (ETDEWEB)

    Valero, A.; Lerch, F.; Serra, L.; Royo, J. [Univ Zaragoza, Zaragoza (Spain). Dept. of Mechanical Engineers

    2002-08-01

    In this second part of the paper, the new advances on thermoeconomic diagnosis presented in the part I are applied to the Escucha power plant, which is a 160 MW conventional coal fired power plant sited in Aragon (Spain). As a result the validity of the methodology is proved and quantified. The methodology is validated using a specific simulator of the Escucha power plant cycle. This simulator reproduces with high accuracy the cycle behavior for different operating conditions, either in design or in off design conditions. The error is lower than 1% in most of cases. The simulated results, i.e. temperatures pressures, mass flow rates, power and so on, are considered as plant measured and validated values thus avoiding measurement uncertainties. A complete thermoeconomic diagnosis is presented applying the Structural Theory of Thermoeconomics. The impact of the component inefficiencies on the fuel plant consumption, and the effect of a component inefficiency (intrinsic malfunction) on the rest of the plant components (induced malfunctions and dysfunctions), are analyzed and quantified. The methodology is validated quantifying its accuracy.

  13. Life-cycle analysis results for geothermal systems in comparison to other power systems: Part II.

    Energy Technology Data Exchange (ETDEWEB)

    Sullivan, J.L.; Clark, C.E.; Yuan, L.; Han, J.; Wang, M. (Energy Systems)

    2012-02-08

    A study has been conducted on the material demand and life-cycle energy and emissions performance of power-generating technologies in addition to those reported in Part I of this series. The additional technologies included concentrated solar power, integrated gasification combined cycle, and a fossil/renewable (termed hybrid) geothermal technology, more specifically, co-produced gas and electric power plants from geo-pressured gas and electric (GPGE) sites. For the latter, two cases were considered: gas and electricity export and electricity-only export. Also modeled were cement, steel and diesel fuel requirements for drilling geothermal wells as a function of well depth. The impact of the construction activities in the building of plants was also estimated. The results of this study are consistent with previously reported trends found in Part I of this series. Among all the technologies considered, fossil combustion-based power plants have the lowest material demand for their construction and composition. On the other hand, conventional fossil-based power technologies have the highest greenhouse gas (GHG) emissions, followed by the hybrid and then two of the renewable power systems, namely hydrothermal flash power and biomass-based combustion power. GHG emissions from U.S. geothermal flash plants were also discussed, estimates provided, and data needs identified. Of the GPGE scenarios modeled, the all-electric scenario had the highest GHG emissions. Similar trends were found for other combustion emissions.

  14. A Review of CAM for Procedural Pain in Infancy: Part II. Other Interventions

    Directory of Open Access Journals (Sweden)

    Jennie C. I. Tsao

    2008-01-01

    Full Text Available This article is the second in a two-part series reviewing the empirical evidence for complementary and alternative medicine (CAM approaches for the management of pain related to medical procedures in infants up to 6 weeks of age. Part I of this series investigated the effects of sucrose with or without non-nutritive sucking (NNS. The present article examines other CAM interventions for procedural pain including music-based interventions, olfactory stimulation, kangaroo care and swaddling. Computerized databases were searched for relevant studies including prior reviews and primary trials. Preliminary support was revealed for the analgesic effects of the CAM modalities reviewed. However, the overall quality of the evidence for these approaches remains relatively weak. Additional well-designed trials incorporating rigorous methodology are required. Such investigations will assist in the development of evidence-based guidelines on the use of CAM interventions either alone or in concert with conventional approaches to provide safe, reliable analgesia for infant procedural pain.

  15. The available-enthalpy (flow-exergy) cycle. Part-II: applications to idealized baroclinic waves

    CERN Document Server

    Marquet, Pascal

    2014-01-01

    The local available-enthalpy cycle proposed in Part I of this paper is applied to document energetics of three numerical simulations, representing life cycles of idealized baroclinic waves. An improved temporal numerical scheme defined in Part I is used in this study, together with the Arpege-IFS model using a T42 triangular truncation. A 45{\\deg}N and 200 hPa dry unstable jet is constructed with the most unstable mode at zonal wave number 8. Energetic impacts of both horizontal and vertical diffusion schemes are determined separately. The role of ageostrophic winds within the Ekman layer is investigated, leading to an explanation for large observed values for the dissipation terms and to a new formulation of the potential-energy conversions. The magnitudes of these new conversion terms are compared with those of the usual barotropic and baroclinic conversions. A new version for the available-enthalpy cycle is proposed. It is suitable for open systems and it includes explicitly the potential-energy component ...

  16. New approach for a reliable in vitro sun protection factor method - Part II: Practical aspects and implementations.

    Science.gov (United States)

    Miksa, S; Lutz, D; Guy, C; Delamour, E

    2016-10-01

    Our previous paper (Part I: Principle and mathematical aspects) presented a new reliable in vitro sun protection factor (SPF) method and demonstrated it to be reproducible and correlated with the in vivo method. Nevertheless, the relevance of an international method should to be adaptable to all products on the market and demonstrated with a blind test. Thus, the aim of this second article was to focus on the practical aspects and implementation (Part II) of a large population of different commercially available sunscreen formulations to obtain similar in vivo SPF results for the purpose of labelling. The method uses the spectroradiometric measurement of residual ultraviolet (UV) through the sample that was applied on a substrate with a robotic appliance. The method has been demonstrated to be highly reliable, and it is based on a multisubstrate solution with a single UV pre-irradiation dose. Furthermore, different categories of the product were studied to identify a reliable and universal in vitro SPF method. Based on different sunscreens products classified into 5 different groups (emulsion, oil, alcohol, stick and powder), it was demonstrated that our method has good reproducibility and accuracy compared with the clinical SPF method. Indeed, the mean coefficient of variation (CV%) was approximately 7%, and the coefficient of correlation reached approximately 0.8-1.0 for different types of tested products. Our second paper concludes that the new in vitro SPF method (based on 113 sunscreen products from the Parts I and II) is clearly adaptable for the SPF labelling purpose on any product type because it is non-invasive, less expensive, more practical and more reliable if performed under strict conditions. © 2016 Society of Cosmetic Scientists and the Société Française de Cosmétologie.

  17. A transverse oscillation approach for estimation of three-dimensional velocity vectors, part II: experimental validation.

    Science.gov (United States)

    Pihl, Michael Johannes; Stuart, Matthias Bo; Tomov, Borislav Gueorguiev; Rasmussen, Morten Fischer; Jensen, Jørgen Arendt

    2014-10-01

    The 3-D transverse oscillation method is investigated by estimating 3-D velocities in an experimental flow-rig system. Measurements of the synthesized transverse oscillating fields are presented as well. The method employs a 2-D transducer; decouples the velocity estimation; and estimates the axial, transverse, and elevation velocity components simultaneously. Data are acquired using a research ultrasound scanner. The velocity measurements are conducted with steady flow in sixteen different directions. For a specific flow direction with [α, ß] = [45, 15]°, the mean estimated velocity vector at the center of the vessel is (v(x), v(y), v(z)) = (33.8, 34.5, 15.2) ± (4.6, 5.0, 0.6) cm/s where the expected velocity is (34.2, 34.2, 13.0) cm/s. The velocity magnitude is 50.6 ± 5.2 cm/s with a bias of 0.7 cm/s. The flow angles α and ß are estimated as 45.6 ± 4.9° and 17.6 ± 1.0°. Subsequently, the precision and accuracy are calculated over the entire velocity profiles. On average for all direction, the relative mean bias of the velocity magnitude is -0.08%. For α and ß, the mean bias is -0.2° and -1.5°. The relative standard deviations of the velocity magnitude ranges from 8 to 16%. For the flow angles, the ranges of the mean angular deviations are 5° to 16° and 0.7° and 8°.

  18. LIDAR TS for ITER core plasma. Part II: simultaneous two wavelength LIDAR TS

    Science.gov (United States)

    Gowers, C.; Nielsen, P.; Salzmann, H.

    2017-12-01

    We have shown recently, and in more detail at this conference (Salzmann et al) that the LIDAR approach to ITER core TS measurements requires only two mirrors in the inaccessible port plug area of the machine. This leads to simplified and robust alignment, lower risk of mirror damage by plasma contamination and much simpler calibration, compared with the awkward and vulnerable optical geometry of the conventional imaging TS approach, currently under development by ITER. In the present work we have extended the simulation code used previously to include the case of launching two laser pulses, of different wavelengths, simultaneously in LIDAR geometry. The aim of this approach is to broaden the choice of lasers available for the diagnostic. In the simulation code it is assumed that two short duration (300 ps) laser pulses of different wavelengths, from an Nd:YAG laser are launched through the plasma simultaneously. The temperature and density profiles are deduced in the usual way but from the resulting combined scattered signals in the different spectral channels of the single spectrometer. The spectral response and quantum efficiencies of the detectors used in the simulation are taken from catalogue data for commercially available Hamamatsu MCP-PMTs. The response times, gateability and tolerance to stray light levels of this type of photomultiplier have already been demonstrated in the JET LIDAR system and give sufficient spatial resolution to meet the ITER specification. Here we present the new simulation results from the code. They demonstrate that when the detectors are combined with this two laser, LIDAR approach, the full range of the specified ITER core plasma Te and ne can be measured with sufficient accuracy. So, with commercially available detectors and a simple modification of a Nd:YAG laser similar to that currently being used in the design of the conventional ITER core TS design mentioned above, the ITER requirements can be met.

  19. Bacterial Community Profiling of Plastic Litter in the Belgian Part of the North Sea.

    Science.gov (United States)

    De Tender, Caroline A; Devriese, Lisa I; Haegeman, Annelies; Maes, Sara; Ruttink, Tom; Dawyndt, Peter

    2015-08-18

    Bacterial colonization of marine plastic litter (MPL) is known for over four decades. Still, only a few studies on the plastic colonization process and its influencing factors are reported. In this study, seafloor MPL was sampled at different locations across the Belgian part of the North Sea to study bacterial community structure using 16S metabarcoding. These marine plastic bacterial communities were compared with those of sediment and seawater, and resin pellets sampled on the beach, to investigate the origin and uniqueness of plastic bacterial communities. Plastics display great variation of bacterial community composition, while each showed significant differences from those of sediment and seawater, indicating that plastics represent a distinct environmental niche. Various environmental factors correlate with the diversity of MPL bacterial composition across plastics. In addition, intrinsic plastic-related factors such as pigment content may contribute to the differences in bacterial colonization. Furthermore, the differential abundance of known primary and secondary colonizers across the various plastics may indicate different stages of bacterial colonization, and may confound comparisons of free-floating plastics. Our studies provide insights in the factors that shape plastic bacterial colonization and shed light on the possible role of plastic as transport vehicle for bacteria through the aquatic environment.

  20. Direct contact membrane distillation for nuclear desalination, Part II: experiments with radioactive solutions

    Energy Technology Data Exchange (ETDEWEB)

    Khayet, M. [Department of Applied Physics I, Faculty of Physics, University Complutense of Madrid, Madrid (Spain)]. E-mail: khayetm@fis.ucm.es; Mengual, J.I. [Department of Applied Physics I, Faculty of Physics, University Complutense of Madrid, Madrid (Spain)]. E-mail: mengual@fis.ucm.es; Zakrzewska-Trznadel, G. [Department of Nuclear Methods in Process Engineering, Institute of Nuclear Chemistry and Technology, Warsaw (Poland)]. E-mail: gzakrzew@orange.ichtj.waw.pl

    2006-07-01

    This paper proposes the application of Direct Contact Membrane Distillation (DCMD) coupled with a nuclear reactor for water desalination and for low- and medium-level radioactive liquid waste concentration. Both laboratory and pilot plant experiments were carried out using the membranes reviewed in Part I of this paper. The effects of process parameters on the productivity and quality of DCMD systems are discussed. Distilled water, non-active solutions of inorganic salts and solutions with admixtures of radionuclides and simulated and real radioactive waste samples were used as feed solutions. Employing DCMD for liquid low- and medium-level radioactive waste processing is an alternative to traditional methods used in nuclear technology. The combination of radioactive waste processing and water desalination creates an economical integrated system for water and wastewater management in nuclear power plants. (author)