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Sample records for profiles palpable time

  1. Palpability Support Demonstrated

    DEFF Research Database (Denmark)

    Brønsted, Jeppe; Grönvall, Erik; Fors, David

    2007-01-01

    the situation. The concept of palpable computing, introduced by the PalCom project, denotes systems which support such understandability. In PalCom, a set of prototype scenarios provide input for an open software architecture and a conceptual framework for palpable computing. One of these prototype scenarios...... is based on the Active Surfaces concept in which therapists rehabilitate physically and mentally impaired children by means of an activity that stimulates the children both physically and cognitively. In this paper we demonstrate how palpability can be supported in a prototype of the Active Surfaces....... Services on the tiles have been developed using the PalCom service framework that allows them to be combined into PalCom assemblies. The support for palpability is shown by examples of use scenarios from the work of the therapist who can inspect and alter the runtime state of the tiles to change...

  2. Postmenopausal palpable ovary and ovarian cancer.

    Science.gov (United States)

    Gojnić, M; Branković, M; Maksimović, M; Parapid, B; Dugalić, V; Jeremić, K; Gutić, B

    2011-01-01

    Ultrasound (US) examination is a much more reliable method for evaluation of potential ovarian cancer risk than gynecologic palpation. The aim of our study was to analyze the US characteristics of patients with palpable ovaries in light of potential for malignancy. We analyzed 70 women ten years after menopause without increased CA 125 values. They underwent clinical and US exams (abdominal and transvaginal ultrasound), with special emphasis on US Doppler exam. Bimanuel gynecological examination showed palpable ovaries in 14 patients (palpable ovary group), and the remaining 56 patients were defined as the control group. US showed increased dimensions of palpable ovaries. Atypical follicular activity, deviation from verticalization, atypical ovaries and hyperechogenic punctations classified under germ cell cysts occurred statistically significantly more often in the palpable ovary group. Doppler flow showed pathological vascularization in five patients with palpable ovaries and the estrogen level was increased. After four to six months in these five patients we found a mild increase of estrogen levels and higher Doppler abnormality. Six months later, two patients had irregular bleeding and underwent surgical treatment. Every adnexal mass after menopausis demands special attention. Bimanuel gynecological exams should be used liberally. It is necessary to follow the dimensions of the ovary, describe the echostructure, as well as the edges of the ovary and other anatomical structures. Doppler flow measurement and estrogen levels are predictive and give more information. Controls should be in three to six month intervals in order to make a decision for surgical treatment.

  3. Palpable Purpura with an Unexpected Outcome

    Directory of Open Access Journals (Sweden)

    Anne Friesgaard Christensen

    2013-01-01

    Full Text Available Scurvy is a potentially lethal condition caused by inadequate vitamin C intake. Hypovitaminosis of vitamin C causes vessel fragility and follicular hyperkeratosis that can lead to palpable purpuric skin lesions. In this case report, we aim to remind readers that scurvy still occurs in Western countries and that the clinical presentation may resemble vasculitis.

  4. Multiple diagnostic approaches to palpable breast mass

    Energy Technology Data Exchange (ETDEWEB)

    Chin, Soo Yil; Kim, Kie Hwan; Moon, Nan Mo; Kim, Yong Kyu; Jang, Ja June [Korea Cancer Center Hospital, Seoul (Korea, Republic of)

    1985-12-15

    The combination of the various diagnostic methods of palpable breast mass has improved the diagnostic accuracy. From September 1983 to August 1985 pathologically proven 85 patients with palpable breast masses examined with x-ray mammography, ultrasonography, penumomammography and aspiration cytology at Korea Cancer Center Hospital were analyzed. The diagnostic accuracies of each methods were 77.6% of mammogram, 74.1% of ultrasonogram, 90.5% of penumomammogram and 92.4% of aspiration cytology. Pneumomammograms was accomplished without difficulty or complication and depicted more clearly delineated mass with various pathognomonic findings; air-ductal pattern in fibroadenoma (90.4%) and cystosarcoma phylloides (100%), air-halo in fibrocystic disease (14.2%), fibroadenoma (100%), cystosarcoma phylloides (100%), air-cystogram in cystic type of fibrocystic disease (100%) and vaculoar pattern or irregular air collection without retained peripheral gas in carcinoma.

  5. Giant Malignant Pheochromocytoma with Palpable Rib Metastases

    Directory of Open Access Journals (Sweden)

    Esat Korgali

    2014-01-01

    Full Text Available Pheochromocytoma is a rare and usually benign neuroendocrine neoplasm. Only 10% of all these tumors are malignant and there are no definitive histological or cytological criteria of malignancy. Single malignancy criteria are the presence of advanced locoregional disease or metastases. We report a case, with a giant retroperitoneal tumor having multiple metastases including palpable rib metastases, who was diagnosed as a malignant pheochromocytoma. The patient was treated with surgery. The literature was reviewed to evaluate tumor features and current diagnostic and therapeutic approaches for patients with metastatic or potentially malignant pheochromocytoma.

  6. Pruritis and palpable purpura from leeches in the Australian Rainforest

    Directory of Open Access Journals (Sweden)

    Elizabeth V. Seiverling

    2014-01-01

    Full Text Available Leeches are prevalent in the Australian Rainforest. We report two cases of leech bites resulting in pruritis and palpable purpura. The dermatologic sequelae of leech bites, differential diagnosis of pruritic palpable purpura, leech bite treatment, prevention, and complications are reviewed.

  7. Refactoring Real-Time Java Profiles

    DEFF Research Database (Denmark)

    Søndergaard, Hans; Thomsen, Bent; Ravn, Anders P.

    2011-01-01

    Just like other software, Java profiles benefits from refactoring when they have been used and have evolved for some time. This paper presents a refactoring of the Real-Time Specification for Java (RTSJ) and the Safety Critical Java (SCJ) profile (JSR-302). It highlights core concepts and makes...

  8. Single high scrotal incision orchidopexy for unilateral palpable testis: A randomised controlled study

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    Almoutaz A. Eltayeb

    2014-01-01

    Full Text Available Background: Bianchi and Squire introduced single high trans-scrotal incision for mobilisation of palpable undescended testes to decrease the potential morbidity of the traditional inguinal approach. This incision has not gained widespread acceptance and there is still a considerable debate about its efficacy. This study evaluated the outcome of high single scrotal incision in comparison to the classic inguinal exploration for unilateral palpable testes regardless to its pre-operative location to assure its validity and safety. Patients and Methods: This was a randomised controlled study conducted on seventy males with palpable unilateral undescended testicles from November 2009 to October 2013. They were divided into two equal groups; group I had high single scrotal incision and group II had the classic inguinal approach. The comparative parameters between both groups were the operative time, intra-and post-operative complications, post-operative pain and scar. Results: There was statistical significant difference between both groups regarding the operative time (P < 0.001. The high scrotal approach (Group I was not completed in three cases and were converted to the classic inguinal approach. No statistical significant difference between both groups regarding the post-operative complications. Conclusions: Single high scrotal incision orchidopexy for palpable undescended testis is safe, has shorter operative time but may not be suitable for proximally lying testis.

  9. Refactoring Real-Time Java Profiles

    DEFF Research Database (Denmark)

    Søndergaard, Hans; Thomsen, Bent; Ravn, Anders Peter

    2011-01-01

    it a suitable foundation for the proposed levels of SCJ. The ongoing work of specifying the SCJ profile builds on sub classing of RTSJ. This spurred our interest in a refactoring approach. It starts by extracting the common kernel of the specifications in a core package, which defines interfaces only......Just like other software, Java profiles benefits from refactoring when they have been used and have evolved for some time. This paper presents a refactoring of the Real-Time Specification for Java (RTSJ) and the Safety Critical Java (SCJ) profile (JSR-302). It highlights core concepts and makes....... It is then possible to refactor SCJ with its three levels and RTSJ in such a way that each profile is in a separate package. This refactoring results in cleaner class hierarchies with no superfluous methods, well defined SCJ levels, elimination of SCJ annotations like @SCJAllowed, thus making the profiles easier...

  10. Single high scrotal incision orchidopexy for unilateral palpable testis ...

    African Journals Online (AJOL)

    Background: Bianchi and Squire introduced single high trans-scrotal incision for mobilisation of palpable undescended testes to decrease the potential morbidity of the traditional inguinal approach. This incision has not gained widespread acceptance and there is still a considerable debate about its efficacy. This study ...

  11. THE VALUE OF ULTRASOUND MAMMOGRAPHY IN PALPABLE BREAST MASSES

    NARCIS (Netherlands)

    VANOORD, JC; VANDERVLIET, AM; THYN, CJP; MAK, B; HOOGEBOOM, GJ

    Between January 1987 and May 1988 a prospective study was carried out on 232 women with a palpable breast mass. They underwent physical examination, x-ray mammography and ultrasound mammography. The results of each study were interpreted independently by separate observers, and consensus was

  12. Clinically palpable breast abnormalities with normal imaging: Is clinically guided biopsy still required?

    Energy Technology Data Exchange (ETDEWEB)

    Gumus, H., E-mail: drhaticegumus@hotmail.com [Department of Radiology, Dicle University, Medical School, Diyarbak Latin-Small-Letter-Dotless-I r (Turkey); Gumus, M. [Department of General Surgery, Dicle University, Medical School, Diyarbak Latin-Small-Letter-Dotless-I r (Turkey); Mills, P. [Department of Radiology, Maidstone Hospital, Maidstone, Kent (United Kingdom); Fish, D. [Department of Pathology, Maidstone Hospital, Maidstone, Kent (United Kingdom); Devalia, H.; Jones, S.E.; Jones, P.A. [Department of Surgery, Maidstone Hospital, Maidstone, Kent (United Kingdom); Sever, Ali R. [Department of Radiology, Maidstone Hospital, Maidstone, Kent (United Kingdom)

    2012-05-15

    Aim: To determine the need for a fine-needle or core biopsy in patients with clinically palpable breast abnormalities who have negative mammographic and sonographic findings. Method and materials: Over a 12-year period, 251 patients with a palpable abnormality at presentation and who had a negative ultrasound and mammogram underwent clinically guided biopsy (CGB) by breast surgeons. This was 2.7% (251/9313) of all breast biopsies performed from January 1999 to December 2010. Physical findings were qualitatively categorized into five groups as clinically 'normal', 'benign', 'probably benign', 'suspicious', and 'malignant' at the time of initial assessment. The number of biopsies for each category and biopsy results were analysed retrospectively. Results: Three (1.2%) of the 251 CGBs were reported as malignant; two (0.8%) of which were invasive. Forty-six (18.3%) of the 251 cases were regarded as clinically suspicious or malignant while the remaining 215 examinations were categorized as benign or probably benign. All three malignancies were in the clinically suspicious or malignant group. Conclusion: A negative ultrasound and mammogram in patients with a palpable abnormality does not exclude breast cancer; however, the likelihood is very low (1.2%). In this study, 81.7% of biopsies (205/251) could have been avoided if CGB was reserved for the clinically suspicious or malignant group only without missing any malignancies.

  13. Diabetic Mastopathy as a Radiographically Occult Palpable Breast Mass

    Directory of Open Access Journals (Sweden)

    Uma Thanarajasingam

    2011-01-01

    Full Text Available Diabetic mastopathy is an uncommon, benign disease of the breast that can occur in women with diabetes and clinically mimic breast cancer. We describe a patient with long-standing type 1 diabetes who presented with a palpable breast mass with negative imaging findings on mammography, ultrasonography, and breast MRI. Surgical biopsy and histopathology confirmed diabetic mastopathy. We use this case to highlight the recognition, radiographic features, pathology, and management of this benign breast condition and emphasize that, in diabetic patients, the differential diagnosis of a new breast mass should include diabetic mastopathy.

  14. Evidence - The intraoral palpability of the lateral pterygoid muscle - A prospective study.

    Science.gov (United States)

    Stelzenmueller, Wolfgang; Umstadt, Horst; Weber, Dominic; Goenner-Oezkan, Volkan; Kopp, Stefan; Lisson, Jörg

    2016-07-01

    The intraoral palpability of the inferior caput of the lateral pterygoid muscle has been a matter of ambiguity because of its topography. Thus, none of the recently published studies has provided reliable proof of the possibility of digital intraoral palpation, although palpation of the muscle is part of most of the examination catalogs for clinical functional analysis and functional therapy. Digital muscle palpation was performed intraorally on five preparations after exposure of the infratemporal fossa and visualization of the lateral pterygoid muscle. Direct digital palpation of the lateral pterygoid muscle was seen in all five cases. The successful palpation was carried out and approved during laterotrusion to the examined side (relaxation). While opening and closing the mouth (contraction) the muscle is palpable. In real-time kinematic measurements (MRI) an impression of the lateral caput of the left lateral pterygoid muscle of a 30-year-old control male person was found up to 6mm. Electromyographic detection by direct signal conduction with concomitant palpation is possible. The injection electrode tested in situ in the muscle was felt transorally with the palpating finger. The intraoral palpability of the inferior caput of the lateral pterygoid muscle is verified. The basic requirement for successfully palpating the lateral pterygoid muscle is the exact knowledge of muscle topography and the intraoral palpation pathway. After documented palpation of the muscle belly in cadaverous preparations, MRI and EMG also visualized palpation of the lateral pterygoid muscle in vivo. The palpation technique seems to be essential and basically feasible. Copyright © 2015 Elsevier GmbH. All rights reserved.

  15. Preoperative localization of non-palpable breast lesion

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    Lee, H. M.; Lee, K. S.; Kim, Y. H.; Choi, H. J.; Cho, B. J. [Cheil General Hospital, Seoul (Korea, Republic of); Lee, D. Y. [Yonsei University College of Medicine, Seoul (Korea, Republic of)

    1994-02-15

    As film-screen mammography became to be used widely, more mammographic abnormalities without palpable masses were detected and the need for surgical biopsied increases. We intended to study the mammographic findings and pathologic diagnosis together with the preoperative localization procedures used in these cases. From Feb. 1987 to Mar. 1993 localization of breast lesion using Breast Needle/Wire Localizer was done in 179 cases. All cases were proven pathologically though surgical biopsy. In these cases, microcalcification(52.0%), mass(29.6%) architectural distortion(2.2%), or combination of the above(16.2%) was observed on film mammogram. Most frequent lesion site was upper outer quadrant(53.1%), followed by upper inner quadrant(25.7%), subareolar area(7.8%), lower outer quadrant(6.7%) and lower inner quadrant(6.7%) in decreasing order of frequency. Cranial(85.5%) approach for needle localization was mostly used but other approaches such as caudal(5.6%), lateral(5.0%) and medial(3.9%) were also used. A total of 24 cases was malignant(13.4%), and among them there were 14 cases of intraductal carcinoma, 1 intralobular carcinoma, 8 invasive ductal carcinoma and 1 invasive lobular carcinoma. With the use of Breast Needle/Wire Localizer, safe, simple and precise localization of non-palpable breast lesion can be achieved. It makes breast biopsy possible with minimal resection of breast tissue therefore minimizing disfigurement of the breast resulting from operation.

  16. Time trends in osteoporosis risk factor profiles

    DEFF Research Database (Denmark)

    Holm, Jakob Præst; Hyldstrup, Lars; Jensen, Jens-Erik Beck

    2016-01-01

    The aim of this article was to identify prevalent osteoporosis risk factors, medications and comorbidities associated with bone mineral density (BMD). Furthermore to evaluate changes in risk factor profiles over 12 years. 6285 women consecutively referred to an osteoporosis specialist clinic were...... included. Information of potential risk factors was obtained by questionnaire and clinical examination. Additional information on medication use, comorbidities and fractures were obtained from national registries. An association (bone health.......7), hyperthyroidism (OR = 1.5), previous major osteoporotic fracture (OR = 1.7), former osteoporosis treatment (OR = 3.5), higher BMI (OR = 0.87), use of calcium supplementation (OR = 1.2), high exercise level (OR = 0.7), and use of thiazide diuretics (OR = 0.7) were identified as predictors of osteoporosis by DXA...

  17. Spatial frequency domain imaging for monitoring palpable breast lesions

    Science.gov (United States)

    Robbins, Constance M.; Antaki, James F.; Kainerstorfer, Jana M.

    2017-02-01

    We describe a novel approach for monitoring breast lesions, utilizing spatial frequency domain imaging, a diffuse optical imaging method to detect hemoglobin contrast, in combination with mechanical compression of the tissue. The project is motivated by the growing rate of unnecessary breast biopsies, caused by uncertainty in X-ray mammographic diagnoses. We believe there is a need for an alternate means of tracking the progression palpable lesions exhibiting probably benign features, that can be performed non-invasively and hence frequently: at home or in the clinic. The proposed approach capitalizes on two distinguishing properties of cancerous lesions, namely the relative stiffness with respect to surrounding tissue and the optical absorption due to the greater vascularization, hence hemoglobin concentration. The current research project is a pilot study to evaluate the principle on soft, breast tissue-mimicking phantoms containing stiffer, more highly absorbing inclusions. Spatial frequency domain imaging was performed by projecting onto the phantom a series of wide-field patterns at multiple spatial frequencies. Image analysis then was performed to map absorption and scattering properties. The results of the study demonstrate that compression significantly increases the optical contrast observed for inclusions located 10 and 15 mm beneath the surface. In the latter case, the inclusion was not detectable without compression.

  18. Ilioinguinal lymph node dissection for palpable metastatic melanoma to the groin.

    Science.gov (United States)

    Allan, Christopher P; Hayes, Andrew J; Thomas, J Meirion

    2008-11-01

    Block dissection of the inguinal lymph nodes is the routine management for palpable metastatic melanoma confined to this node basin. Involvement of the next tier external iliac and obturator lymph nodes in the pelvis is common, and untreated pelvic nodal disease can become advanced before becoming clinically apparent. We have routinely performed combined inguinal and pelvic (ilioinguinal) lymph node block dissection to avoid this morbid outcome. A retrospective analysis of all patients undergoing ilioinguinal lymph node dissection for melanoma between January 1998 and January 2006 was carried out. There were 72 patients with a median age of 52.7 years (19.7-75.2 years) who were followed up for a median of 28.9 months (1.0-115.0 months) after ilioinguinal lymph node dissection. There were 22 (30.6%) of 72 patients with histologically involved pelvic lymph nodes. Preoperative computed tomography (CT) scanning accuracy for pelvic lymph node involvement was as follows: sensitivity 60.0%, specificity 100.0%, positive predictive value 100.0% and negative predictive value 86.2%. Lymphoedema was reported in 32 (44.4%) of 72 patients. Median time to first recurrence was 8.7 months (0.8-69.7 months). Regional recurrence occurred in 6 (8.3%) of 72 patients at a median of 4.9 months (0.9-32.0 months). Extranodal spread was the only factor adversely associated with disease-free survival. In all patients, 5-year disease-free survival was 38% (95% confidence interval (CI) 26-50) and overall survival 47% (95% CI 33-60). Palpable metastatic melanoma in the groin is commonly associated with pelvic lymph node involvement, is not well predicted by CT scanning and is appropriately managed by ilioinguinal lymph node block dissection.

  19. Clinical anatomy and palpability of the inferior lateral pterygoid muscle.

    Science.gov (United States)

    Stratmann, U; Mokrys, K; Meyer, U; Kleinheinz, J; Joos, U; Dirksen, D; Bollmann, F

    2000-05-01

    The intraoral palpation technique of the inferior belly of the inferior lateral pterygoid (ILP) muscle is a standard diagnostic examination method for temporomandibular joint dysfunction syndrome, although different studies have revealed inconsistent results. This study assessed the feasibility of the ILP muscle palpation by a simulated clinical setting. Three dentists performed a bilateral palpation of the ILP muscle in 53 fresh and unfixed human cadavers and decided whether the muscle was palpable or unpalpable. In a second step, it was observed through the dissected infratemporal fossa, whether the examiner's finger did or did not touch the ILP muscle by simulating the performed palpation. Palpatory findings were supplemented by 1-dimensional measurements for determination of topographic relations of the ILP muscle within the infratemporal fossa. For statistical analysis, sensitivity, specificity, and negative and positive predictive values of the palpation technique were calculated. Interexaminer agreement was estimated with the kappa value. In 86 of 106 dissected specimens, a superficial fascicle of the medial pterygoid muscle was found in direct proximity to the ILP muscle. In these cases, a residual distance of 7.8 +/- 3.2 mm remained between the ILP muscle and buccinator fascia indented by the tip of the examiner's finger. In 10 of 20 specimens with an absent superficial fascicle, the finger was able to reach the ILP muscle. It is recommended that the ILP muscle palpation technique should no longer be considered as a standard clinical procedure because it is nearly impossible to palpate the ILP muscle anatomically and because the risk of false-positive findings (by palpation of the medial pterygoid muscle) is high.

  20. Multi-Detector CT Findings of Palpable Chest Wall Masses in Children: A Pictorial Essay

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    Park, Chan Ho; Kim, Young Tong [Dept. of Radiology, Soonchunhyang University College of Medicine, Cheonan Hospital, Cheonan (Korea, Republic of); Hong, Hyun Sook [Dept. of Radiology, Soonchunhyang University College of Medicine, Bucheon Hospital, Bucheon (Korea, Republic of)

    2013-03-15

    A wide variety of diseases manifest as palpable chest wall masses in children. These include normal variation, congenital anomalies, trauma, infection, axillary lymphadenopathies, soft tissue tumors and bone tumors. Given that most of these diseases are associated with chest wall deformity, diagnosis is difficult by physical examination or ultrasonography alone. However, multi-detector CT with three dimensional reconstruction is useful in the characterization and differential diagnosis of palpable chest wall lesions. In this article, we review the spectrum of palpable chest wall diseases and illustrate their multi-detector CT presentation.

  1. Image guided versus palpation guided core needle biopsy of palpable breast masses: a prospective study

    Directory of Open Access Journals (Sweden)

    Smriti Hari

    2016-01-01

    Interpretation & conclusions: Our results showed that in palpable breast masses, image guided biopsy was superior to palpation guided biopsy in terms of sensitivity, false negative rate and repeat biopsy rates.

  2. Feasibility of magnetic marker localisation for non-palpable breast cancer

    NARCIS (Netherlands)

    Schermers, B.; van der Hage, Jos A.; Loo, C.E.; Vrancken Peeters, M.T.F.D.; Winter-Warnars, H. A.O.; Duijnhoven, F.H.; ten Haken, B.; Muller, S.H.; Ruers, T. J.M.

    2017-01-01

    Objectives Accurate tumour localisation is essential for breast-conserving surgery of non-palpable tumours. Current localisation technologies are associated with disadvantages such as logistical challenges and migration issues (wire guided localisation) or legislative complexities and high

  3. Metabolic profile at first-time schizophrenia diagnosis

    DEFF Research Database (Denmark)

    Horsdal, Henriette Thisted; Benros, Michael Eriksen; Köhler-Forsberg, Ole

    2017-01-01

    -time schizophrenia diagnosis were identified, of whom 1,040 (42.4%) were monitored for metabolic abnormalities. Among those monitored, 58.4% had an abnormal lipid profile and 13.8% had an abnormal glucose profile. People who had previously filled prescription(s) for antipsychotic drugs were more likely to present...... an abnormal lipid measure (65.7% vs 46.8%, Pprofile (16.4% vs 10.1%, P=0.01). CONCLUSION: Metabolic abnormalities are common at first schizophrenia diagnosis, particularly among those with previous antipsychotic prescription(s). Increased metabolic abnormalities already present...... abnormalities and characterized the metabolic profiles in people with a first-time schizophrenia diagnosis. METHODS: This is a population-based cross-sectional study including all adults born in Denmark after January 1, 1955, with their first schizophrenia diagnosis between 2000 and 2012 in the Central Denmark...

  4. Metabolic profile at first-time schizophrenia diagnosis

    DEFF Research Database (Denmark)

    Horsdal, Henriette Thisted; Benros, Michael Eriksen; Köhler-Forsberg, Ole

    2017-01-01

    OBJECTIVE: Schizophrenia and/or antipsychotic drug use are associated with metabolic abnormalities; however, knowledge regarding metabolic status and physician's monitoring of metabolic status at first schizophrenia diagnosis is sparse. We assessed the prevalence of monitoring for metabolic blood...... abnormalities and characterized the metabolic profiles in people with a first-time schizophrenia diagnosis. METHODS: This is a population-based cross-sectional study including all adults born in Denmark after January 1, 1955, with their first schizophrenia diagnosis between 2000 and 2012 in the Central Denmark......-time schizophrenia diagnosis were identified, of whom 1,040 (42.4%) were monitored for metabolic abnormalities. Among those monitored, 58.4% had an abnormal lipid profile and 13.8% had an abnormal glucose profile. People who had previously filled prescription(s) for antipsychotic drugs were more likely to present...

  5. Orchiopexy-laparoscopy or traditional surgical technique in patients with an undescended palpable testicle.

    Science.gov (United States)

    Escarcega-Fujigaki, Pastor; Rezk, Guillermo Hernandez-Peredo; Huerta-Murrieta, Edgar; Lezama-Ramirez, Nancy; Hernandez-Gomez, Santiago; Kuri-Cortes, Gerardo; Bañuelos-Montano, Abimael

    2011-03-01

    To compare orchiopexy by laparoscopy versus traditional surgical technique in patients with an undescended palpable testicle in the inguinal canal. A prospective, comparative, observational, longitudinal, and double-blind research was done between August 2006 and March 2009 in the Centro de Especialidades Médicas del Estado de Veracruz, "Dr. Rafael Lucio"; 63 patients underwent surgery, age 1-10 years, all with the diagnosis of palpable undescended testicle in the inguinal canal; in 33 patients, the traditional surgical technique and in 30 patients laparoscopy were done. A visual analogue scale (VAS) was used to evaluate post-surgery pain. A testicle ultrasound was practiced before surgery and at 6 months after it. The majority of patients were 1-4 years old with a median age of 2.3 years; 51 cases were unilateral and 12 cases were bilateral; 37 testicles were descended with the open traditional surgical technique and 38 through laparoscopy (75 testicles); 44 on the right side and 31 on the left side; there was a hernia associated with 37 undescended testicles, 23 with open surgical technique, and 14 by laparoscopy, without relapsing in any patient. The median surgery time with the open surgical technique was 38 minutes and by laparoscopy, it was 45 minutes. The gobernaculum testis was sectioned by laparoscopy in 23 descended testicles to facilitate the procedure, in the remaining 11 it was not necessary; whereas in the open technique, all the gobernaculum testis were sectioned. In 80% of cases, the laparoscopy caused less pain when compared with the other technique. All patients regardless of the technique used left hospital during the first 24 hours. All have had follow-up for more than 6 months with a median of 18 months, with satisfactory results in relation to size and location of the testicle, with a good ultrasound correlation, and not finding any statistical differences between surgical techniques. There were no accidents with any of the techniques, and 1

  6. Generate stepper motor linear speed profile in real time

    Science.gov (United States)

    Stoychitch, M. Y.

    2018-01-01

    In this paper we consider the problem of realization of linear speed profile of stepper motors in real time. We considered the general case when changes of speed in the phases of acceleration and deceleration are different. The new and practical algorithm of the trajectory planning is given. The algorithms of the real time speed control which are suitable for realization to the microcontroller and FPGA circuits are proposed. The practical realization one of these algorithms, using Arduino platform, is given also.

  7. A model for quantification of temperature profiles via germination times

    DEFF Research Database (Denmark)

    Pipper, Christian Bressen; Adolf, Verena Isabelle; Jacobsen, Sven-Erik

    2013-01-01

    Current methodology to quantify temperature characteristics in germination of seeds is predominantly based on analysis of the time to reach a given germination fraction, that is, the quantiles in the distribution of the germination time of a seed. In practice interpolation between observed...... germination fractions at given monitoring times is used to obtain the time to reach a given germination fraction. As a consequence the obtained value will be highly dependent on the actual monitoring scheme used in the experiment. In this paper a link between currently used quantile models for the germination...... time and a specific type of accelerated failure time models is provided. As a consequence the observed number of germinated seeds at given monitoring times may be analysed directly by a grouped time-to-event model from which characteristics of the temperature profile may be identified and estimated...

  8. The force-time profile of elite front crawl swimmers.

    Science.gov (United States)

    Formosa, Danielle P; Mason, Bruce; Burkett, Brendan

    2011-05-01

    In this study, we used recently developed technology to determine the force-time profile of elite swimmers, which enabled coaches to make informed decisions on technique modifications. Eight elite male swimmers with a FINA (Federation Internationale de Natation) rank of 900+ completed five passive (streamline tow) and five net force (arms and leg swimming) trials. Three 50-Hz cameras were used to video each trial and were synchronized to the kinetic data output from a force-platform, upon which a motorized towing device was mounted. Passive and net force trials were completed at the participant's maximal front crawl swimming velocity. For the constant tow velocity, the net force profile was presented as a force-time graph, and the limitation of a constant velocity assumption was acknowledged. This allowed minimum and maximum net forces and arm symmetry to be identified. At a mean velocity of 1.92+0.06 m s⁻¹, the mean passive drag for the swimmers was 80.3+4.0 N, and the mean net force was 262.4+33.4 N. The mean location in the stroke cycle for minimum and maximum net force production was at 45% (insweep phase) and 75% (upsweep phase) of the stroke, respectively. This force-time profile also identified any stroke asymmetry.

  9. On the Anonymity Risk of Time-Varying User Profiles

    Directory of Open Access Journals (Sweden)

    Silvia Puglisi

    2017-04-01

    Full Text Available Websites and applications use personalisation services to profile their users, collect their patterns and activities and eventually use this data to provide tailored suggestions. User preferences and social interactions are therefore aggregated and analysed. Every time a user publishes a new post or creates a link with another entity, either another user, or some online resource, new information is added to the user profile. Exposing private data does not only reveal information about single users’ preferences, increasing their privacy risk, but can expose more about their network that single actors intended. This mechanism is self-evident in social networks where users receive suggestions based on their friends’ activities. We propose an information-theoretic approach to measure the differential update of the anonymity risk of time-varying user profiles. This expresses how privacy is affected when new content is posted and how much third-party services get to know about the users when a new activity is shared. We use actual Facebook data to show how our model can be applied to a real-world scenario.

  10. Questions of time and affect: a person's affectivity profile, time perspective, and well-being.

    Science.gov (United States)

    Garcia, Danilo; Sailer, Uta; Nima, Ali Al; Archer, Trevor

    2016-01-01

    Background. A "balanced" time perspective has been suggested to have a positive influence on well-being: a sentimental and positive view of the past (high Past Positive), a less pessimistic attitude toward the past (low Past Negative), the desire of experiencing pleasure with slight concern for future consequences (high Present Hedonistic), a less fatalistic and hopeless view of the future (low Present Fatalistic), and the ability to find reward in achieving specific long-term goals (high Future). We used the affective profiles model (i.e., combinations of individuals' experience of high/low positive/negative affectivity) to investigate differences between individuals in time perspective dimensions and to investigate if the influence of time perspective dimensions on well-being was moderated by the individual's type of profile. Method. Participants (N = 720) answered to the Positive Affect Negative Affect Schedule, the Zimbardo Time Perspective Inventory and two measures of well-being: the Temporal Satisfaction with Life Scale and Ryff's Scales of Psychological Well-Being-short version. A Multivariate Analysis of Variance (MANOVA) was conducted to identify differences in time perspective dimensions and well-being among individuals with distinct affective profiles. Four structural equation models (SEM) were used to investigate which time perspective dimensions predicted well-being for individuals in each profile. Results. Comparisons between individuals at the extreme of the affective profiles model suggested that individuals with a self-fulfilling profile (high positive/low negative affect) were characterized by a "balanced" time perspective and higher well-being compared to individuals with a self-destructive profile (low positive/high negative affect). However, a different pattern emerged when individuals who differed in one affect dimension but matched in the other were compared to each other. For instance, decreases in the past negative time perspective

  11. The value of ultrasonography in boys with a non-palpable testis

    NARCIS (Netherlands)

    Vos, Alexander; Vries, Annebeth Meij-de; Smets, Anne; Verbeke, Jonathan; Heij, Hugo; van der Steeg, Alida

    2014-01-01

    In patients with a non-palpable testis (NPT) on physical examination, the testis is assumed either to be situated intra-abdominally or to be hypoplastic or absent. Diagnostic laparoscopy in these boys is considered the preferable first step. In this study the diagnostic value of pre-operative

  12. HER2 Over Expression in Malignant Palpable Breast Lumps of Pre ...

    African Journals Online (AJOL)

    HER2 Over Expression in Malignant Palpable Breast Lumps of Pre and Postmenopausal Women Attending RICK. ... Back ground: Human Epidermal growth factor Receptor 2 (HER-2/neu) over expression in breast cancer is associated with poor outcome and decrease ... Results: HER-2/neu + vein first pregnancy at .

  13. Role of dynamic sentinel node biopsy in carcinoma penis with or without palpable nodes

    Directory of Open Access Journals (Sweden)

    N Kathiresan

    2016-01-01

    Conclusion: DSLNB is a useful and reliable technique to identify the involved node(s in patients diagnosed as having carcinoma penis with clinical N0 status (with or without palpable nodes. It helps to avoid the morbidity associated with a staging inguinal dissection in these patients.

  14. Criticality: static profiling for real-time programs

    DEFF Research Database (Denmark)

    Brandner, Florian; Hepp, Stefan; Jordan, Alexander

    2014-01-01

    -case execution time (WCET) and its associated worst-case execution path (WCEP) only. However, both, the WCET and the WCEP, only provide partial information. Only code parts that are on one of the WCEPs are indicated to the programmer. No information is provided for all other code parts. To give a comprehensive......With the increasing performance demand in real-time systems it becomes more and more important to provide feedback to programmers and software development tools on the performance-relevant code parts of a real-time program. So far, this information was limited to an estimation of the worst...... view covering the entire code base, tools in the spirit of program profiling are required. This work proposes an efficient approach to compute worst-case timing information for all code parts of a program using a complementary metric, called criticality. Every statement of a program is assigned...

  15. Average waiting time profiles of uniform DQDB model

    Energy Technology Data Exchange (ETDEWEB)

    Rao, N.S.V. [Oak Ridge National Lab., TN (United States); Maly, K.; Olariu, S.; Dharanikota, S.; Zhang, L.; Game, D. [Old Dominion Univ., Norfolk, VA (United States). Dept. of Computer Science

    1993-09-07

    The Distributed Queue Dual Bus (DQDB) system consists of a linear arrangement of N nodes that communicate with each other using two contra-flowing buses; the nodes use an extremely simple protocol to send messages on these buses. This simple, but elegant, system has been found to be very challenging to analyze. We consider a simple and uniform abstraction of this model to highlight the fairness issues in terms of average waiting time. We introduce a new approximation method to analyze the performance of DQDB system in terms of the average waiting time of a node expressed as a function of its position. Our approach abstracts the intimate relationship between the load of the system and its fairness characteristics, and explains all basic behavior profiles of DQDB observed in previous simulation. For the uniform DQDB with equal distance between adjacent nodes, we show that the system operates under three basic behavior profiles and a finite number of their combinations that depend on the load of the network. Consequently, the system is not fair at any load in terms of the average waiting times. In the vicinity of a critical load of 1 {minus} 4/N, the uniform network runs into a state akin to chaos, where its behavior fluctuates from one extreme to the other with a load variation of 2/N. Our analysis is supported by simulation results. We also show that the main theme of the analysis carries over to the general (non-uniform) DQDB; by suitably choosing the inter-node distances, the DQDB can be made fair around some loads, but such system will become unfair as the load changes.

  16. Injectable iodine-125 labeled tissue marker for radioactive localization of non-palpable breast lesions

    DEFF Research Database (Denmark)

    Schaarup-Jensen, Henrik; Jensen, Andreas Ingemann; Hansen, Anders Elias

    2018-01-01

    through thin hypodermic needles (≥27G), the marker holds great promise for clinical application, since patient discomfort is reduced significantly compared to current methods. Statement of Significance. A new type of tissue marker for local administration to non-palpable breast tumors has been developed......We have developed a 125I-radiolabeled injectable fiducial tissue marker with the potential to replace current methods used for surgical guidance of non-palpable breast tumors. Methods in routine clinical use today such as radioactive seed localization, radio-guided occult lesion localization...... and wire-guided localization suffers from limitations that this injectable fiducial tissue marker offers solutions to. The developed 125I-radiolabeled injectable fiducial tissue marker is based on highly viscous sucrose acetate isobutyrate. The marker was readily inserted in NMRI mice and proved...

  17. A preliminary study of shear wave elastography for the evaluation of unilateral palpable undescended testes.

    Science.gov (United States)

    Ucar, Ayse Kalyoncu; Alis, Deniz; Samanci, Cesur; Aslan, Mine; Habibi, Hatice Arioz; Dikici, Atilla Suleyman; Namdar, Yesim; Gultekin, Mehmet Hamza; Onal, Bulent; Adaletli, Ibrahim

    2017-01-01

    We sought to compare unilateral palpable undescended testes and contralateral descended testes using shear wave elastography (SWE) to show potential quantitative differences in elasticity patterns, which might reflect the histologic features. Approval for this prospective study was obtained from the local ethics committee. A total of 29 patients (mean age, 7.52 years; range, 1-18 years) with unilateral palpable undescended testes and contralateral descended testes were examined by greyscale ultrasonography and SWE between February 2015 and April 2016. The volume and the elasticity of each testicle were the main factors evaluated. There was no difference between undescended testes and contralateral descended testes in terms of volume. However, a significant difference was evident in SWE-derived quantitative data. SWE seems to be a useful sonographic technique to predict histologic features of the undescended testicle, which might replace testicular biopsy in modern management of the undescended testis. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  18. A Case report: Pseudoangiomatous stromal hyperplasia (PASH tumor presenting as a palpable mass.

    Directory of Open Access Journals (Sweden)

    Jean eBouquet De Jolinière

    2016-01-01

    Full Text Available We report a case of woman with a palpable lump on her left breast. On mammography a huge mass located between the inner and outer inferior breast quadrants of the left breast was found. The ultrasound examination realized later revealed a heterogeneous mass with smooth and lobulated borders. A MRI was also performed, showing an oval mass with heterogeneous areas of enhancement. Finally a core biopsy under sonographic guidance revealed a pseudo angiomatous stromal hyperplasia of the breast (PASH.

  19. Outcomes of routine ilioinguinal lymph node dissection for palpable inguinal melanoma nodal metastasis.

    Science.gov (United States)

    Glover, A R; Allan, C P; Wilkinson, M J; Strauss, D C; Thomas, J M; Hayes, A J

    2014-06-01

    Patients who present with palpable inguinal melanoma nodal metastasis have two surgical options: inguinal or ilioinguinal lymph node dissection. Indications for either operation remain controversial. This study examined survival and recurrence outcomes following ilioinguinal dissection for patients with palpable inguinal nodal metastasis, and assessed the incidence and preoperative predictors of pelvic nodal metastasis. This was a retrospective clinicopathological analysis of consecutive surgical patients with stage III malignant melanoma. All patients underwent a standardized ilioinguinal dissection at a specialist tertiary oncology hospital over a 12-year period (1998-2010). Some 38.9 per cent of 113 patients had metastatic pelvic nodes. Over a median follow-up of 31 months, the 5-year overall survival rate was 28 per cent for patients with metastatic inguinal and pelvic nodes, and 51 per cent for those with inguinal nodal metastasis only (P = 0.002). The nodal basin control rate was 88.5 per cent. Despite no evidence of pelvic node involvement on preoperative computed tomography (CT), six patients (5.3 per cent) with a single metastatic inguinal lymph node had metastatic pelvic lymph nodes. Logistic regression analysis showed that the number of metastatic inguinal nodes (odds ratio 1.56; P = 0.021) and suspicious CT findings (odds ratio 9.89; P = 0.001) were both significantly associated with metastatic pelvic nodes. The specificity of CT was good (89.2 per cent) in detecting metastatic pelvic nodes, but the sensitivity was limited (57.9 per cent). Metastatic pelvic nodes are common when palpable metastatic inguinal nodes are present. Long-term survival can be achieved following their resection by ilioinguinal dissection. As metastatic pelvic nodes cannot be diagnosed reliably by preoperative CT, patients presenting with palpable inguinal nodal metastasis should be considered for ilioinguinal dissection. © 2014 BJS Society Ltd. Published by John Wiley & Sons

  20. Ultrasonographic features and clinical implications of benign palpable breast lesions in young women

    Energy Technology Data Exchange (ETDEWEB)

    Ha, Richard; Kim, Hyon Ah; Mango, Victoria; Wynn, Ralph [Dept. of Radiology, Columbia University Medical Center, New York (United States); Comstock, Christopher [Dept. of Radiology, Memorial Sloan Kettering Cancer Center, New York (United States)

    2015-01-15

    The purpose of this study was to describe the breast ultrasonography (US) features and to investigate whether performing a core biopsy is warranted in young women having palpable solid breast masses. A total of 76 solid palpable masses in 68 consecutive women (≤25 years old) underwent tissue diagnosis by percutaneous core biopsy. Two radiologists, who were blinded to the clinical history and histopathology, independently evaluated the US features according to Breast Imaging-Reporting and Data System (BI-RADS) lexicon. The frequency of benign and malignant descriptor terms that were used to characterize the lesions were compared to the final pathology. All 76 palpable solid masses yielded benign pathology. On the US, the shape of the mass was described by radiologists 1 and 2 as oval or round (63.2% and 71.1%), margin as circumscribed (68.4% and 77.6%) and orientation as parallel (85.5% and 90.8%); the frequency of using all three benign descriptors was 61.8% and 68.5%, respectively. Suspicious descriptors were used less frequently by radiologists 1 and 2 including irregular shape (9.2% and 13.1%), non-circumscribed margin (31.6% and 22.4%) and non-parallel orientation (14.5% and 9.2%); the frequency of using all three suspicious descriptors was 9.2% and 11.8%, respectively. Despite the variable US features, breast malignancy seems extremely low in 25 years or younger women for palpable breast lesions. Using the BI-RADS lexicon, US accurately predicted benignity in about two thirds of our patients, supporting US surveillance as a safe alternative to invasive tissue sampling in this setting.

  1. Image guided versus palpation guided core needle biopsy of palpable breast masses: a prospective study

    OpenAIRE

    Smriti Hari; Swati Kumari; Anurag Srivastava; Sanjay Thulkar; Sandeep Mathur; Prasad Thotton Veedu

    2016-01-01

    Background & objectives: Biopsy of palpable breast masses can be performed manually by palpation guidance or under imaging guidance. Based on retrospective studies, image guided biopsy is considered more accurate than palpation guided breast biopsy; however, these techniques have not been compared prospectively. We conducted this prospective study to verify the superiority and determine the size of beneficial effect of image guided biopsy over palpation guided biopsy. Methods: Over a period o...

  2. Ultrasonographic features and clinical implications of benign palpable breast lesions in young women

    Directory of Open Access Journals (Sweden)

    Richard Ha

    2015-01-01

    Full Text Available Purpose: The purpose of this study was to describe the breast ultrasonography (US features and to investigate whether performing a core biopsy is warranted in young women having palpable solid breast masses. Methods: A total of 76 solid palpable masses in 68 consecutive women (≤25 years old underwent tissue diagnosis by percutaneous core biopsy. Two radiologists, who were blinded to the clinical history and histopathology, independently evaluated the US features according to Breast Imaging-Reporting and Data System (BI-RADS lexicon. The frequency of benign and malignant descriptor terms that were used to characterize the lesions were compared to the final pathology. Results: All 76 palpable solid masses yielded benign pathology. On the US, the shape of the mass was described by radiologists 1 and 2 as oval or round (63.2% and 71.1%, margin as circumscribed (68.4% and 77.6% and orientation as parallel (85.5% and 90.8%; the frequency of using all three benign descriptors was 61.8% and 68.5%, respectively. Suspicious descriptors were used less frequently by radiologists 1 and 2 including irregular shape (9.2% and 13.1%, non-circumscribed margin (31.6% and 22.4% and non-parallel orientation (14.5% and 9.2%; the frequency of using all three suspicious descriptors was 9.2% and 11.8%, respectively. Conclusion: Despite the variable US features, breast malignancy seems extremely low in 25 years or younger women for palpable breast lesions. Using the BI-RADS lexicon, US accurately predicted benignity in about two thirds of our patients, supporting US surveillance as a safe alternative to invasive tissue sampling in this setting.

  3. Time-resolved beam profiler for pulsed lasers

    Science.gov (United States)

    Klick, David I.; Knight, Frederick K.

    1993-04-01

    A high-speed imaging device based on a streak camera has been demonstrated, which provides multiple images from non-repeatable transient events of time scale >= 1 ns. It can be employed for pulsed laser beam diagnostics, measuring laser beam spatial and temporal structure on a single-pulse basis. The system currently has angular resolution of 16 X 16 pixels, with a time resolution of 250 ps. The laser beam width is sized to fill the input optic, and the image is dissected by a square array of optical fibers. At the other end of the fiber optic image converter, the 256 fibers form a line array, which is input to the slit of a streak camera. The streak camera sweeps the input line across the output phosphor screen so that position is directly proportional to time. The resulting 2-D image (fiber position vs. time) at the phosphor is read by an intensified (SIT) vidicon TV tube, and the image is digitized and stored. A computer subsequently decodes the image, unscrambling the linear pixels into an angle-angle image at each time. We are left with a series of snapshots, each one depicting the laser beam spatial profile (intensity cross-section) at succeeding moments in time. The system can currently record several hundred images over a span of 25 to 400 ns. This detector can study lasers of pulse width >= 1 ns and with a visible wavelength (200 - 900 nm). Candidate lasers include doubled Nd:YAG, excimer, ruby, nitrogen, metal vapor, and Ti:Sapphire. The system could also be simply configured as an 8 X 8 element wavefront sensor to record the cross-sectional distribution of phase, as well as amplitude. Finally, suggestions for system improvement are detailed, and the ultimate limitations of the method in terms of spatial and temporal resolution are discussed.

  4. Técnicas de biopsia para el diagnóstico de lesiones mamarias no palpables Biopsy techniques for the diagnosis of non-palpable mammary lesions

    OpenAIRE

    L. Pina; L. Apesteguía; E. de Luis; J. Sáenz Bañuelos; G. Zornoza; F. Domínguez Cunchillos

    2004-01-01

    Ante una lesión mamaria no palpable que precise una biopsia diagnóstica debe valorarse el método de guiado idóneo para acceder a la misma. En la actualidad se emplean tres métodos: la estereotaxia (fundamentalmente en casos de microcalcificaciones), la ecografía (sobre todo en los nódulos) y la resonancia magnética (para lesiones no visibles mediante los anteriores sistemas). El siguiente paso es elegir la técnica de biopsia más adecuada. La técnica más clásica y fiable es la biopsia quirúrgi...

  5. Stability and change in teachers' goal orientation profiles over time : Managerial coaching behavior as a predictor of profile change

    NARCIS (Netherlands)

    Kunst, E.M.; van Woerkom, M.; van Kollenburg, G.H.; Poell, R.F.

    2018-01-01

    Goal orientation is an important predictor of motivation at work. This study introduces goal orientation profiles in the work domain, evaluates their stability over time and assesses the impact of managerial coaching behavior on change in employees' goal orientation profiles. We hypothesize that

  6. Image guided versus palpation guided core needle biopsy of palpable breast masses: a prospective study.

    Science.gov (United States)

    Hari, Smriti; Kumari, Swati; Srivastava, Anurag; Thulkar, Sanjay; Mathur, Sandeep; Veedu, Prasad Thotton

    2016-05-01

    Biopsy of palpable breast masses can be performed manually by palpation guidance or under imaging guidance. Based on retrospective studies, image guided biopsy is considered more accurate than palpation guided breast biopsy; however, these techniques have not been compared prospectively. We conducted this prospective study to verify the superiority and determine the size of beneficial effect of image guided biopsy over palpation guided biopsy. Over a period of 18 months, 36 patients each with palpable breast masses were randomized into palpation guided and image guided breast biopsy arms. Ultrasound was used for image guidance in 33 patients and mammographic (stereotactic) guidance in three patients. All biopsies were performed using 14 gauge automated core biopsy needles. Inconclusive, suspicious or imaging-histologic discordant biopsies were repeated. Malignancy was found in 30 of 36 women in palpation guided biopsy arm and 27 of 36 women in image guided biopsy arm. Palpation guided biopsy had sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of 46.7, 100, 100, 27.3 per cent, respectively, for diagnosing breast cancer. Nineteen of 36 women (52.8%) required repeat biopsy because of inadequate samples (7 of 19), suspicious findings (2 of 19) or imaging-histologic discordance (10 of 19). On repeat biopsy, malignancy was found in all cases of imaging-histologic discordance. Image guided biopsy had 96.3 per cent sensitivity and 100 per cent specificity. There was no case of inadequate sample or imaging-histologic discordance with image guided biopsy. Our results showed that in palpable breast masses, image guided biopsy was superior to palpation guided biopsy in terms of sensitivity, false negative rate and repeat biopsy rates.

  7. Cytokine expression profile over time in severely burned pediatric patients

    National Research Council Canada - National Science Library

    Finnerty, Celeste C; Herndon, David N; Przkora, Rene; Pereira, Clifford T; Oliveira, Hermes M; Queiroz, Dulciene M M; Rocha, Andreia M C; Jeschke, Marc G

    2006-01-01

    .... The massive release of cytokines is implicated in this hypermetabolic response. The aim of the present study was to compare cytokine expression profiles from severely burned children without signs of infections or inhalation injury (n = 19...

  8. Biopsia core de lesiones mamarias palpables: Experiencia del Hospital El Pino

    OpenAIRE

    MENESES C,LUIS; ASPEE L,CLAUDIO; MALDONADO U,CECILIA; LINARES A,VICTOR; PALMA A,PAULA

    2007-01-01

    La biopsia core percutánea guiada por palpación es el procedimiento más utilizado en el diagnóstico preoperatorio de lesiones mamarias palpables, sin embargo para asegurar una tasa de éxitos razonable se requiere un diámetro mínimo de la lesión por debajo del cual se debe recurrir a otros medios como la punción core ecodirigida. Usualmente esta discriminación se realiza según criterio y experiencia del tratante. Con el objetivo de definir referencias objetivas de selección del método, particu...

  9. Peritoneography for diagnosis of non-palpable hernias. Peritoneographie zum Nachweis nicht tastbarer Hernien

    Energy Technology Data Exchange (ETDEWEB)

    Schumacher, K.H.

    1981-01-01

    The detection of non-palpable hernia by means of peritoneography is almost unknown in the German-speaking areas. By injection of an iodine-containing contrast medium into the abdominal cavity, and with the corresponding positioning of the patient, a hernia can certainly be diagnosed or excluded. This method is indicated in cases of inguinal pain with undetected genesis, particularly in adipose patients, for detecting recidivous hernias with postoperative complaints, for the diagnosis of traumatic hernias or abdominal wall hernias. Between July 1, 1979 and December 31, 1980 peritoneography was performed in 154 patients in Bruchsal Hospital in order to detect herniae.

  10. Incidentally detection of non-palpable testicular nodules at scrotal ultrasound: What is new?

    Directory of Open Access Journals (Sweden)

    Massimo Valentino

    2014-12-01

    Full Text Available The increased use of ultrasound in patients with urological and andrological symptoms has given an higher detection of intra-testicular nodules. Most of these lesions are hypoechoic and their interpretation is often equivocal. Recently, new ultrasound techniques have been developed alongside of B-mode and color-Doppler ultrasound. Although not completely standardized, contrast-enhanced ultrasound (CEUS and tissue elastography (TE, added to traditional ultrasonography, can provide useful information about the correct interpretation of incidentally detected non-palpable testicular nodules. The purpose of this review article is to illustrate these new techniques in the patient management.

  11. Palpable mass of the neck in the course of Takayasu arteritis.

    Science.gov (United States)

    Andrzejewska, Karolina; Starba, Aleksandra; Misterska-Skóra, Maria; Wiland, Piotr; Guziński, Maciej

    2017-01-01

    Takayasu arteritis is a rare, idiopathic inflammatory disease of the aorta and its major branches, usually affecting young women of Asian descent. In the course of the disease stenosis, occlusions as well as dilatations and aneurysms of vessels occur. Because of many possible localizations of pathological changes, the symptoms have a wide range, but the most common are a weak pulse or its absence on the brachial artery and a difference in systolic pressure above 10 mm Hg between the upper extremities. Here we present a case report of a young woman with Takayasu arteritis, who presented a palpable mass in the back of her neck, significantly diminished after treatment with glucocorticoids.

  12. Characteristics of CSF Velocity-Time Profile in Posttraumatic Syringomyelia.

    Science.gov (United States)

    Yeo, J; Cheng, S; Hemley, S; Lee, B B; Stoodley, M; Bilston, L

    2017-09-01

    The development of syringomyelia has been associated with changes in CSF flow dynamics in the spinal subarachnoid space. However, differences in CSF flow velocity between patients with posttraumatic syringomyelia and healthy participants remains unclear. The aim of this work was to define differences in CSF flow above and below a syrinx in participants with posttraumatic syringomyelia and compare the CSF flow with that in healthy controls. Six participants with posttraumatic syringomyelia were recruited for this study. Phase-contrast MR imaging was used to measure CSF flow velocity at the base of the skull and above and below the syrinx. Velocity magnitudes and temporal features of the CSF velocity profile were compared with those in healthy controls. CSF flow velocity in the spinal subarachnoid space of participants with syringomyelia was similar at different locations despite differences in syrinx size and locations. Peak cranial and caudal velocities above and below the syrinx were not significantly different (peak cranial velocity, P = .9; peak caudal velocity, P = 1.0), but the peak velocities were significantly lower (P < .001, P = .007) in the participants with syringomyelia compared with matched controls. Most notably, the duration of caudal flow was significantly shorter (P = .003) in the participants with syringomyelia. CSF flow within the posttraumatic syringomyelia group was relatively uniform along the spinal canal, but there are differences in the timing of CSF flow compared with that in matched healthy controls. This finding supports the hypothesis that syrinx development may be associated with temporal changes in spinal CSF flow. © 2017 by American Journal of Neuroradiology.

  13. [Stereotactic vacuum-assisted breast biopsy (Mammotome biopsy) for non-palpable microcalcification on mammography].

    Science.gov (United States)

    Matsuzaki, Saeko; Shiba, Eiichi; Kobayashi, Yasushi; Kawai, Mieko; Kitamura, Kaeko; Nishita, Toshiyuki; Nishio, Hiroshi; Kobayashi, Nobuyuki

    2005-01-01

    The purpose of this study was to assess the benefits of stereotactic vacuum-assisted breast biopsy in patients with non-palpable microcalcification detected on mammography. Between October 2001 and November 2003, stereotactic Mammotome biopsies were performed for 150 microcalcified lesions on mammography using the prone-type stereotactic vacuum-assisted breast biopsy system (Mammotest and Mammovision, Fischer, Denver, USA) . The mammography findings were classified according to the guidelines of The Japan Radiological Society/The Japan Association of Radiological Technologists. Ninety-eight cases were category 3, 38 were category 4, and 14 were category 5. All cases were determined to be cases of microcalcification by specimen radiography or histology. Complications were negligible. One hundred twenty of the cases were mastopathy, and 30 of them were breast cancer (14 were ductal carcinoma in situ, 7 were ductal carcinoma in situ with microinvasion, and 9 were invasive ductal carcinoma). Twenty-seven breast cancers were diagnosed as category 4 or 5 (51.9%) on mammography. The operative stages of 27 cases were as follows: 7 were stage 0, 17 were stage 1, and 3 were stage 2A. Twenty-four of 27 (88.9%) were early breast cancers. Mammotome biopsy is a safe and useful modality for the histological diagnosis of non-palpable microcalcifications.

  14. Real-time feedback control of the plasma density profile on ASDEX Upgrade

    Science.gov (United States)

    Mlynek, A.; Reich, M.; Giannone, L.; Treutterer, W.; Behler, K.; Blank, H.; Buhler, A.; Cole, R.; Eixenberger, H.; Fischer, R.; Lohs, A.; Lüddecke, K.; Merkel, R.; Neu, G.; Ryter, F.; Zasche, D.; ASDEX Upgrade Team

    2011-04-01

    The spatial distribution of density in a fusion experiment is of significant importance as it enters in numerous analyses and contributes to the fusion performance. The reconstruction of the density profile is therefore commonly done in offline data analysis. In this paper, we present an algorithm which allows for density profile reconstruction from the data of the submillimetre interferometer and the magnetic equilibrium in real-time. We compare the obtained results to the profiles yielded by a numerically more complex offline algorithm. Furthermore, we present recent ASDEX Upgrade experiments in which we used the real-time density profile for active feedback control of the shape of the density profile.

  15. Latent Profiles of Perceived Time Adequacy for Paid Work, Parenting, and Partner Roles

    Science.gov (United States)

    Lee, Soomi; Almeida, David M.; Davis, Kelly D.; King, Rosalind B.; Hammer, Leslie B.; Kelly, Erin L.

    2015-01-01

    This study examined feelings of having enough time (i.e., perceived time adequacy) in a sample of employed parents (N=880) in information technology and extended-care industries. Adapting a person-centered latent profile approach, we identified three profiles of perceived time adequacy for paid work, parenting, and partner roles: Family Time Protected, Family Time Sacrificed, and Time Balanced. Drawing upon the Conservation of Resources theory (Hobfòll, 1989), we examined the associations of stressors and resources with the time adequacy profiles. Parents in the Family Time Sacrificed profile were more likely to be younger, women, have younger children, work in the extended-care industry, and have nonstandard work schedules compared to those in the Family Time Protected profile. Results from multinomial logistic regression analyses revealed that, with the Time Balanced profile as the reference group, having fewer stressors and more resources in the family context (less parent-child conflict and more partner support), work context (longer company tenure, higher schedule control and job satisfaction), and work-family interface (lower work-to-family conflict) was linked to a higher probability of membership in the Family Time Protected profile. By contrast, having more stressors and fewer resources, in the forms of less partner support and higher work-to-family conflict, predicted a higher likelihood of being in the Family Time Sacrificed profile. Our findings suggest that low work-to-family conflict is the most critical predictor of membership in the Family Time Protected profile, whereas lack of partner support is the most important factor to be included in the Family Time Sacrificed profile. PMID:26075739

  16. Cytokine expression profile over time in severely burned pediatric patients.

    Science.gov (United States)

    Finnerty, Celeste C; Herndon, David N; Przkora, Rene; Pereira, Clifford T; Oliveira, Hermes M; Queiroz, Dulciene M M; Rocha, Andreia M C; Jeschke, Marc G

    2006-07-01

    A severe burn leads to hypermetabolism and catabolism resulting in compromised function and structure of essential organs. The massive release of cytokines is implicated in this hypermetabolic response. The aim of the present study was to compare cytokine expression profiles from severely burned children without signs of infections or inhalation injury (n = 19) to the cytokine profiles from normal, noninfected, nonburned children (n = 14). The Bio-Plex suspension array system was used to measure the concentration of 17 cytokines. The expression of proinflammatory and anti-inflammatory cytokines was maximal during the first week after thermal injury. Significant increases were measured for 15 mediators during the first week after thermal injury: interleukin (IL) 1beta, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12 p70, IL-13, IL-17, interferon gamma, monocyte chemoattractant protein 1, macrophage inflammatory protein 1beta, and granulocyte colony-stimulating factor (P sepsis. The cytokine concentrations decrease during 5 weeks after burn but remain elevated over nonburned values. Furthermore, the elevation in most serum cytokine levels during the first week after burn may indicate a potential window of opportunity for therapeutic intervention.

  17. Adjuvant Radiotherapy for Palpable Melanoma Metastases to the Groin: When to Irradiate?

    Energy Technology Data Exchange (ETDEWEB)

    Gojkovic-Horvat, Andreja; Jancar, Boris [Department of Radiation Oncology, Institute of Oncology Ljubljana, Ljubljana (Slovenia); Blas, Mateja [Department of Statistics, Institute of Oncology Ljubljana, Ljubljana (Slovenia); Zumer, Barbara; Karner, Katarina [Department of Radiation Oncology, Institute of Oncology Ljubljana, Ljubljana (Slovenia); Hocevar, Marko [Department of Surgical Oncology, Institute of Oncology Ljubljana, Ljubljana (Slovenia); Strojan, Primoz, E-mail: pstrojan@onko-i.si [Department of Radiation Oncology, Institute of Oncology Ljubljana, Ljubljana (Slovenia)

    2012-05-01

    Purpose: To determine the efficacy of and criteria for postoperative radiotherapy (PORT) in patients with palpable melanoma metastases to the groin. Methods and Materials: Patients with palpable metastases to the groin who were treated with therapeutic nodal dissection during 2000 to 2006 were identified in a prospective institutional database. Results: In 101 patients, 103 therapeutic nodal dissections were performed; 37 of these were treated with PORT to a median equivalent dose (eqTD{sub 2}) of 50.6 Gy (range, 50-72 Gy). In the surgery-only and PORT groups, 2-year regional control rates were 86% (95% confidence interval [CI] 76-95%) and 91% (95% CI, 81-100%), respectively (p = 0.395). Of five recurrences in radiation-treated patients, four were of dermal type, and in three of these cases, no bolus over the operative scar was used. PORT improved 2-year regional control (46% [95% CI, 11-82%] vs. 82% [95% CI, 63-100%], p = 0.022) among patients in which the sum of risk factors present (i.e., risk factor score) was {>=}2. In multivariate analysis, risk-factor score (<2 vs. {>=}2: HR, 2.93; 95% CI, 1.00-8.56; p < 0.0001) and PORT (yes vs. no: HR, 7.81; 95% CI, 2.83-21.74; p = 0.050) was predictive for regional control and on logistic-regression testing, number of involved lymph nodes was predictive for systemic dissemination (p = 0.011). Conclusions: PORT should follow therapeutic nodal dissection in cases with two or more adverse factors. More conventional fractionation ({<=}2.5 Gy), cumulative eqTD{sub 2} <60 Gy and use of bolus over the operative scar are recommended.

  18. Role of dynamic sentinel node biopsy in carcinoma penis with or without palpable nodes.

    Science.gov (United States)

    Kathiresan, N; Raja, Anand; Ramachandran, Krishna Kumar; Sundersingh, Shirley

    2016-01-01

    We aimed to evaluate the role of dynamic sentinel node biopsy (DSLNB) in patients diagnosed with carcinoma penis and clinically N0 disease using superficial inguinal dissection as the standard staging modality. Twenty consecutive men (40 groins) with carcinoma penis having clinically N0 status were enrolled in the study. Patients underwent DSLNB if fine needle aspiration cytology from the groin nodes was negative, followed by injection of radiocolloid and blue dye. The sentinel lymph node(s) were harvested. The inguinal incision was then extended and a modified superficial inguinal dissection was performed and all nodes were labeled separately and sent for frozen section. A completion deep inguinal with pelvic dissection was performed if any of the nodes were reported positive for malignancy. The median age of the patients was 52.5 years. Ten patients were smokers. Phimosis was present in five patients. Lesions were present over the glans penis and shaft in 18 and two patients, respectively. Wide local excision, partial penectomy and total penectomy were performed in one, 15 and four patients, respectively. Clinically palpable nodes were found in 19 groins. Median follow-up was 26 months. Nodes were positive in 10 groins. DSLNB missed the sentinel node in one groin. The accuracy and false-negative rate of DSLNB was 97.5% and 10%, respectively. DSLNB is a useful and reliable technique to identify the involved node(s) in patients diagnosed as having carcinoma penis with clinical N0 status (with or without palpable nodes). It helps to avoid the morbidity associated with a staging inguinal dissection in these patients.

  19. A real-time intercepting beam-profile monitor for a medical cyclotron

    Science.gov (United States)

    Hendriks, C.; Uittenbosch, T.; Cameron, D.; Kellogg, S.; Gray, D.; Buckley, K.; Schaffer, P.; Verzilov, V.; Hoehr, C.

    2013-11-01

    There is a lack of real-time continuous beam-diagnostic tools for medical cyclotrons due to high power deposition during proton irradiation. To overcome this limitation, we have developed a profile monitor that is capable of providing continuous feedback about beam shape and current in real time while it is inserted in the beam path. This enables users to optimize the beam profile and observe fluctuations in the beam over time with periodic insertion of the monitor.

  20. Real-Time Detection of Infrared Profile Patterns and Features Extraction

    OpenAIRE

    Usamentiaga, Rub&#;n; Garc?a, Daniel F.; Molleda, Julio

    2008-01-01

    In this work, a method to detect infrared profiles patterns in real-time is proposed. The method is based on real-time segmentation of infrared images acquired using an infrared line-scanner. The segmentation is based on the detection of edges which indicate the change of the current infrared profile pattern. The segmentation consists of the calculation of the gradient, its projection, and its thresholding. These three steps are designed to be applied in real-time. Therefore, the information ...

  1. A real-time intercepting beam-profile monitor for a medical cyclotron.

    Science.gov (United States)

    Hendriks, C; Uittenbosch, T; Cameron, D; Kellogg, S; Gray, D; Buckley, K; Schaffer, P; Verzilov, V; Hoehr, C

    2013-11-01

    There is a lack of real-time continuous beam-diagnostic tools for medical cyclotrons due to high power deposition during proton irradiation. To overcome this limitation, we have developed a profile monitor that is capable of providing continuous feedback about beam shape and current in real time while it is inserted in the beam path. This enables users to optimize the beam profile and observe fluctuations in the beam over time with periodic insertion of the monitor.

  2. Clinical Value of Mammography in the Evaluation of Palpable Breast Lumps in Women 30 Years Old and Older.

    Science.gov (United States)

    Brown, Ann L; Phillips, Jordana; Slanetz, Priscilla J; Fein-Zachary, Valerie; Venkataraman, Shambhavi; Dialani, Vandana; Mehta, Tejas S

    2017-10-01

    The purpose of this study was to determine whether mammography adds clinical value in the diagnostic imaging workup of women 30 years old and older who present with palpable breast lumps. We retrospectively identified the records of all women 30 years old and older who underwent imaging evaluation with mammography and ultrasound for a palpable lump between January 1, 2009, and December 31, 2010. Imaging reports were reviewed for findings related to the lump and for incidental nonpalpable findings. Benign versus malignant outcomes were determined by pathologic analysis or 24-month imaging or clinical follow-up. The contribution of mammography to final diagnosis was assessed on the basis of objective criteria to determine the clinical impact of mammographic findings. The study cohort included 861 patients presenting with 935 palpable lumps. Imaging correlates were reported for 568 of 935 (60.7%) lumps, and imaging findings were negative in 367 of 935 (39.3%). Of the 935 palpable lumps, 858 (91.8%) were benign and 77 (8.2%) were malignant. Mammography added clinical value in the evaluation of 27 of 77 (35.0%) malignant lumps by better delineating extent of disease and in the evaluation of 26 of 858 benign lumps (3.0%) by confirming benignity. Fifty-two of 861 (6.0%) patients had incidental findings that led to a recommendation for biopsy. Twenty-nine of the 52 findings were originally seen with mammography and 23 with ultrasound. Mammography also depicted seven incidental malignancies in nonpalpable areas, and ultrasound depicted one incidental malignancy. Adjunct mammography is warranted for evaluation of palpable breast lumps in women 30 years old and older because of the value added to clinical management. In all age cohorts, mammography contributed to delineation of disease extent, detection of incidental malignancies, and confirmation of benign diagnoses.

  3. Questions of time and affect: a person’s affectivity profile, time perspective, and well-being

    Science.gov (United States)

    Sailer, Uta; Nima, Ali Al; Archer, Trevor

    2016-01-01

    Background. A “balanced” time perspective has been suggested to have a positive influence on well-being: a sentimental and positive view of the past (high Past Positive), a less pessimistic attitude toward the past (low Past Negative), the desire of experiencing pleasure with slight concern for future consequences (high Present Hedonistic), a less fatalistic and hopeless view of the future (low Present Fatalistic), and the ability to find reward in achieving specific long-term goals (high Future). We used the affective profiles model (i.e., combinations of individuals’ experience of high/low positive/negative affectivity) to investigate differences between individuals in time perspective dimensions and to investigate if the influence of time perspective dimensions on well-being was moderated by the individual’s type of profile. Method. Participants (N = 720) answered to the Positive Affect Negative Affect Schedule, the Zimbardo Time Perspective Inventory and two measures of well-being: the Temporal Satisfaction with Life Scale and Ryff’s Scales of Psychological Well-Being-short version. A Multivariate Analysis of Variance (MANOVA) was conducted to identify differences in time perspective dimensions and well-being among individuals with distinct affective profiles. Four structural equation models (SEM) were used to investigate which time perspective dimensions predicted well-being for individuals in each profile. Results. Comparisons between individuals at the extreme of the affective profiles model suggested that individuals with a self-fulfilling profile (high positive/low negative affect) were characterized by a “balanced” time perspective and higher well-being compared to individuals with a self-destructive profile (low positive/high negative affect). However, a different pattern emerged when individuals who differed in one affect dimension but matched in the other were compared to each other. For instance, decreases in the past negative time

  4. Routine activities and time use: a latent profile approach to sexual offenders' lifestyles.

    Science.gov (United States)

    Pedneault, Amelie; Beauregard, Eric

    2014-02-01

    The routine activities of a sample of 147 incarcerated sexual offenders were studied. During interviews conducted between 1994 and 2000 in a province of Canada, data were collected on the participants' time involvement in a variety of activities in the weeks preceding their index sexual offense(s). Using latent profile analysis, a typology of lifestyles of sexual offenders was created. Five distinct profiles were identified. The inactive loner was characterized by little time involvement with their romantic partners and social activities. The social traveler spent the highest time driving and reported the highest number of friends. The single walker reported the highest amount of time walking around. The partyers' lifestyle was centered around alcohol and drugs. Finally, offenders from the familial homebody profile spent most of their time at home. Differences between profiles were investigated with regard to characteristics of index sexual offense.

  5. Estimation of dynamic flux profiles from metabolic time series data

    Directory of Open Access Journals (Sweden)

    Chou I-Chun

    2012-07-01

    Full Text Available Abstract Background Advances in modern high-throughput techniques of molecular biology have enabled top-down approaches for the estimation of parameter values in metabolic systems, based on time series data. Special among them is the recent method of dynamic flux estimation (DFE, which uses such data not only for parameter estimation but also for the identification of functional forms of the processes governing a metabolic system. DFE furthermore provides diagnostic tools for the evaluation of model validity and of the quality of a model fit beyond residual errors. Unfortunately, DFE works only when the data are more or less complete and the system contains as many independent fluxes as metabolites. These drawbacks may be ameliorated with other types of estimation and information. However, such supplementations incur their own limitations. In particular, assumptions must be made regarding the functional forms of some processes and detailed kinetic information must be available, in addition to the time series data. Results The authors propose here a systematic approach that supplements DFE and overcomes some of its shortcomings. Like DFE, the approach is model-free and requires only minimal assumptions. If sufficient time series data are available, the approach allows the determination of a subset of fluxes that enables the subsequent applicability of DFE to the rest of the flux system. The authors demonstrate the procedure with three artificial pathway systems exhibiting distinct characteristics and with actual data of the trehalose pathway in Saccharomyces cerevisiae. Conclusions The results demonstrate that the proposed method successfully complements DFE under various situations and without a priori assumptions regarding the model representation. The proposed method also permits an examination of whether at all, to what degree, or within what range the available time series data can be validly represented in a particular functional format of

  6. Visual analytics of signalling pathways using time profiles.

    Science.gov (United States)

    Ma, David K G; Stolte, Christian; Kaur, Sandeep; Bain, Michael; O'Donoghue, Seán I

    2015-01-01

    Data visualisation is usually a crucial first step in analysing and exploring large-scale complex data. The visualisation of proteomics time-course data on post-translational modifications presents a particular challenge that is largely unmet by existing tools and methods. To this end, we present Minardo, a novel visualisation strategy tailored for such proteomics data, in which data layout is driven by both cellular topology and temporal order. In this work, we utilised the Minardo strategy to visualise a dataset showing phosphorylation events in response to insulin. We evaluated the visualisation together with experts in diabetes and obesity, which led to new insights into the insulin response pathway. Based on this success, we outline how this layout strategy could be automated into a web-based tool for visualising a broad range of proteomics time-course data. We also discuss how the approach could be extended to include protein 3D structure information, as well as higher dimensional data, such as a range of experimental conditions. We also discuss our entry of Minardo in the international DREAM8 competition.

  7. A Mathematical Technique for Estimating True Temperature Profiles of Data Obtained from Long Time Constant Thermocouples

    National Research Council Canada - National Science Library

    Young, Graeme

    1998-01-01

    A mathematical modeling technique is described for estimating true temperature profiles of data obtained from long time constant thermocouples, which were used in fuel fire tests designed to determine...

  8. Time-course profiling of molecular stress responses to silver nanoparticles in the earthworm Eisenia fetida

    DEFF Research Database (Denmark)

    Hayashi, Yuya; Heckmann, Lars-Henrik; Simonsen, Vibeke

    2013-01-01

    The molecular mechanism of silver nanoparticle (AgNP) toxicity, particularly its temporal aspect, is currently limited in the literature. This study seeks to identify and profile changes in molecular response patterns over time during soil exposure of the earthworm Eisenia fetida to AgNPs (82±27 nm......) with reference to dissolved silver salt (AgNO3). Principal component analysis of selected gene and enzyme response profiles revealed dissimilar patterns between AgNO3 and AgNP treatments and also over time. Despite the observed difference in molecular profiles, the body burdens of total Ag were within the same...

  9. Localization techniques for guided surgical excision of non-palpable breast lesions.

    Science.gov (United States)

    Chan, Benjamin K Y; Wiseberg-Firtell, Jill A; Jois, Ramesh H S; Jensen, Katrin; Audisio, Riccardo A

    2015-12-31

    Breast cancer is the most common form of cancer and the second leading cause of death amongst women in Europe. Amongst five invasive cancers per 1000 women detected in screening, 2.7 were Organization (WHO) International Clinical Trials Registry Platform (ICTRP) search portal from the earliest available date up to 30 March 2015. We also handsearched recent conference proceedings and sought information from experts in the field. Two review authors, BC and RJ, independently screened by title and abstract the studies we had identified through the search strategy; when this was inconclusive, they examined the full-text article for inclusion. We resolved any discrepancies regarding eligibility by discussion with a third review author, RA. Three review authors, BC, JW, and RJ, independently extracted data using a standardized data sheet. We performed all analyses using Review Manager (RevMan) or the R meta package, and in accordance with the Cochrane Handbook for Systematic Reviews of Interventions. We reported results via a graphical assessment using forest plots showing the study estimates. We considered and discussed additional subgroup and sensitivity analyses. We identified 11 randomized controlled trials (RCTs) that met the inclusion criteria of this Cochrane review and included eight trials in the meta-analyses. Six RCTs compared radioguided occult lesion localization (ROLL) versus WGL, and two RCTs compared radioactive iodine ((125)I) seed localization (RSL) versus WGL. Of the three remaining trials, one RCT compared cryo-assisted techniques (CAL) versus WGL, one compared intraoperative ultrasound-guided lumpectomy (IOUS) versus WGL, and one compared modified ROLL technique in combination with methylene dye (RCML) versus WGL. Of the trials we included in the meta-analysis, there were a total of 1273 participants with non-palpable breast lesions (627 participants (WGL); 443 participants (ROLL); and 203 participants (RSL)). The participant population varied

  10. Semantic and Time-Dependent Expertise Profiling Models in Community-Driven Knowledge Curation Platforms

    Directory of Open Access Journals (Sweden)

    Jane Hunter

    2013-10-01

    Full Text Available Online collaboration and web-based knowledge sharing have gained momentum as major components of the Web 2.0 movement. Consequently, knowledge embedded in such platforms is no longer static and continuously evolves through experts’ micro-contributions. Traditional Information Retrieval and Social Network Analysis techniques take a document-centric approach to expertise modeling by creating a macro-perspective of knowledge embedded in large corpus of static documents. However, as knowledge in collaboration platforms changes dynamically, the traditional macro-perspective is insufficient for tracking the evolution of knowledge and expertise. Hence, Expertise Profiling is presented with major challenges in the context of dynamic and evolving knowledge. In our previous study, we proposed a comprehensive, domain-independent model for expertise profiling in the context of evolving knowledge. In this paper, we incorporate Language Modeling into our methodology to enhance the accuracy of resulting profiles. Evaluation results indicate a significant improvement in the accuracy of profiles generated by this approach. In addition, we present our profile visualization tool, Profile Explorer, which serves as a paradigm for exploring and analyzing time-dependent expertise profiles in knowledge-bases where content evolves overtime. Profile Explorer facilitates comparative analysis of evolving expertise, independent of the domain and the methodology used in creating profiles.

  11. A quantitative measure of the structure of gamma-ray burst time profiles

    Science.gov (United States)

    Lestrade, John P.; Fishman, G.; Horack, J.; Meegan, C.; Moore, P.; Paciesas, W.; Wilson, R.

    1992-01-01

    A cursory examination of cosmic gamma-ray burst time profiles indicates an inhomogeneous distribution of structure. In the first approximation, there seem to be two types of profiles; smooth ones with little structure and highly variable ones with lots of structure. To put this observation to the test, we have examined the statistical nature of the profile derivative to choose which parameter might best be called the burst 'spikiness'. We have found that a good estimator is given by a count of the number of 'spikes' (defined by a specific numerical recipe) and not by the rms deviations from either a pre-burst background or any type of moving average background. The application of this parameter to 30 burst time histories shows it to be consistent over a wide range of profile types. The analysis also reveals a preferred average time between spikes of approximately 1.5 seconds.

  12. Efficient reconstruction of dispersive dielectric profiles using time domain reflectometry (TDR

    Directory of Open Access Journals (Sweden)

    P. Leidenberger

    2006-01-01

    Full Text Available We present a numerical model for time domain reflectometry (TDR signal propagation in dispersive dielectric materials. The numerical probe model is terminated with a parallel circuit, consisting of an ohmic resistor and an ideal capacitance. We derive analytical approximations for the capacitance, the inductance and the conductance of three-wire probes. We couple the time domain model with global optimization in order to reconstruct water content profiles from TDR traces. For efficiently solving the inverse problem we use genetic algorithms combined with a hierarchical parameterization. We investigate the performance of the method by reconstructing synthetically generated profiles. The algorithm is then applied to retrieve dielectric profiles from TDR traces measured in the field. We succeed in reconstructing dielectric and ohmic profiles where conventional methods, based on travel time extraction, fail.

  13. Analyzing the gene expression profile of pediatric acute myeloid leukemia with real-time PCR arrays

    OpenAIRE

    Yan-Fang Tao; Dong Wu; Li Pang; Wen-Li Zhao; Jun Lu; Na Wang; Jian Wang; Xing Feng; Yan-Hong Li; Jian Ni; Jian Pan

    2012-01-01

    Abstract Background The Real-time PCR Array System is the ideal tool for analyzing the expression of a focused panel of genes. In this study, we will analyze the gene expression profile of pediatric acute myeloid leukemia with real-time PCR arrays. Methods Real-time PCR array was designed and tested firstly. Then gene expression profile of 11 pediatric AML and 10 normal controls was analyzed with real-time PCR arrays. We analyzed the expression data with MEV (Multi Experiment View) cluster so...

  14. Palpable pediatric thyroid abnormalities – diagnostic pitfalls necessitate a high index of clinical suspicion: a case report

    Directory of Open Access Journals (Sweden)

    Klopper Joshua P

    2007-06-01

    Full Text Available Abstract A 12-year-old girl presented with a 4 year history of an enlarged, firm thyroid gland. On exam, her thyroid was firm and fixed and an enlarged cervical lymph node was palpable as well. Though a thyroid ultrasound prior to referral was read as thyroiditis, clinical suspicion for thyroid carcinoma mandated continued investigation. The diagnosis of papillary thyroid cancer was established and her workup revealed lymph node metastases as well as a tremendous burden of pulmonary metastases. Pediatric thyroid cancer is extremely rare, but often presents with aggressive disease. Palpable thyroid abnormalities in an individual under 20-years-old should be viewed with suspicion and should be thoroughly investigated to rule out malignancy even in the face of negative diagnostic procedures. Though pediatric papillary thyroid cancer often presents with loco-regional and even distant metastatic disease, mortality rates in follow-up for as long as 20 years are very favorable.

  15. Real-time, profile-corrected single snapshot imaging of optical properties

    Science.gov (United States)

    van de Giessen, Martijn; Angelo, Joseph P.; Gioux, Sylvain

    2015-01-01

    A novel acquisition and processing method that enables real-time, single snapshot of optical properties (SSOP) and 3-dimensional (3D) profile measurements in the spatial frequency domain is described. This method makes use of a dual sinusoidal wave projection pattern permitting to extract the DC and AC components in the frequency domain to recover optical properties as well as the phase for measuring the 3D profile. In this method, the 3D profile is used to correct for the effect of sample’s height and angle and directly obtain profile-corrected absorption and reduced scattering maps from a single acquired image. In this manuscript, the 3D-SSOP method is described and validated on tissue-mimicking phantoms as well as in vivo, in comparison with the standard profile-corrected SFDI (3D-SFDI) method. On average, in comparison with 3D-SFDI method, the 3D-SSOP method allows to recover the profile within 1.2mm and profile-corrected optical properties within 12% for absorption and 6% for reduced scattering over a large field-of-view and in real-time. PMID:26504653

  16. Ultrasonic transit-time flowmeters modelled with theoretical velocity profiles: methodology

    Science.gov (United States)

    Moore, Pamela I.; Brown, Gregor J.; Stimpson, Brian P.

    2000-12-01

    Fully developed flow is well defined for most values of Reynolds number but distorted flow is not. Velocity profile is the definition given to the distribution of velocity in the axial direction over the cross-section of the pipe. This distribution is not usually uniform and can vary dramatically depending on the properties of the fluid and the configuration of the pipe in which it flows. Ultrasonic flowmeters are affected by such distortions in the flow profile, often resulting in erroneous measurements. Transit-time ultrasonic flowmeters are widely used in industry in distorted fluid flows, therefore correction to or prediction of distorted profiles has sparked great interest in the design and application of ultrasonic flowmeters. This document describes a method for modelling and analysing the effect of theoretical asymmetric flow profiles on ultrasonic flowmeters of the transit-time type, thus allowing an understanding of installation effects.

  17. A real-time beam-profile monitor for a PET cyclotron

    Science.gov (United States)

    Hoehr, C.; Uittenbosch, T.; Verzilov, V.; English, W.; Buckley, K.; Gray, D.; Kellog, S.; Cameron, D.; Schaffer, P.

    2012-12-01

    Beam profiles in medical cyclotrons are traditionally measured using techniques that do not provide any information about short-term fluctuations of the beam shape or beam intensity. To overcome this, we have developed a real-time harp beam profile monitor which can withstand beam power in excess of 300 W. The monitor and electronics were constructed and applied toward a 13 MeV proton beam with current of up to 25 μA. Herein are reported preliminary beam-profile measurement results.

  18. An abnormal screening mammogram causes more anxiety than a palpable lump in benign breast disease.

    Science.gov (United States)

    Keyzer-Dekker, C M G; van Esch, L; de Vries, J; Ernst, M F; Nieuwenhuijzen, G A P; Roukema, J A; van der Steeg, A F W

    2012-07-01

    Being recalled for further diagnostic procedures after an abnormal screening mammogram (ASM) can evoke a high state anxiety with lowered quality of life (QoL). We examined whether these adverse psychological consequences are found in all women with benign breast disease (BBD) or are particular to women referred after ASM. In addition, the influence of the anxiety as a personality characteristic (trait anxiety) was studied. Between September 2002 and February 2010 we performed a prospective longitudinal study in six Dutch hospitals. Women referred after ASM or with a palpable lump in the breast (PL), who were subsequently diagnosed with BBD, were included. Before diagnosis (at referral) and during follow-up, questionnaires were completed examining trait anxiety (at referral), state anxiety, depressive symptoms (at referral, one, three and 6 months after diagnosis), and QoL (at referral and 12 months). Women referred after ASM (N=363) were compared with women with PL (N=401). A similar state anxiety score was found in both groups, but a lower psychological QoL score at 12 months was seen in the ASM group. In women with not-high trait anxiety those in the ASM group were more anxious with more depressive symptoms at referral, and reported impaired psychological QoL at referral and at 12 months compared with the PL group. No differences were found between ASM and PL in women with high trait anxiety, but this group scored unfavorably on anxiety, depressive symptoms and QoL compared with women with not-high trait anxiety. ASM evokes more anxiety and depressive symptoms and lowered QoL compared with women referred with PL, especially in women who are not prone to anxiety. Women should be fully informed properly about the risks and benefits of breast cancer screening programs. We recommend identifying women at risk of reduced QoL using a psychometric test.

  19. 99mTc-3PRGD2 Scintimammography in Palpable and Nonpalpable Breast Lesions

    Directory of Open Access Journals (Sweden)

    Lin Liu

    2014-07-01

    Full Text Available The aim of this study was to explore the diagnostic performance of 99mTc-3(poly-(ethylene glycol,PEG4-RGD2 (99mTc-3PRGD2 scintimammography (SMM in patients with either palpable or nonpalpable breast lesions and compare SMM to mammography to assess the possible incremental value of SMM in breast cancer detection. We also investigated the αvβ3 expression in malignant and benign breast lesions. Ninety-four patients with 110 lesions were included in this study. Mammograms were evaluated according to the Breast Imaging Reporting and Data System (BI-RADS by a specialized imaging radiologist. Prone SMM was performed 1 hour after injection of 99mTc-3PRGD2. Scintigraphic images were interpreted independently by two experienced nuclear medicine physicians using a three-point system, and the kappa value was calculated to determine the interreader agreement. The McNemar test was used to compare SMM and mammography with respect to sensitivity, specificity, and accuracy. Diagnostic values for breast cancer detection were evaluated for each lesion. Immunohistochemistry was performed to evaluate integrin αvβ3 expression. Histopathology revealed 46 malignant lesions and 64 benign lesions. The overall sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of SMM were 83%, 73%, 77%, 69%, and 85%, respectively. The kappa value between the two reviewers was 0.63. The diagnostic values of SMM were higher than those of mammography in evaluating overall breast lesions. A sensitivity of 91% was achieved when SMM and mammography results were combined with 60% of all false-negative mammography findings classified as true-positive results by SMM. Integrin αvβ3 expression was positively identified using SMM imaging. SMM is a promising tool to avoid unnecessary biopsies when used in addition to mammography and can be used to image αvβ3 expression in breast cancer with good image quality.

  20. A method to identify differential expression profiles of time-course gene data with Fourier transformation.

    Science.gov (United States)

    Kim, Jaehee; Ogden, Robert Todd; Kim, Haseong

    2013-10-18

    Time course gene expression experiments are an increasingly popular method for exploring biological processes. Temporal gene expression profiles provide an important characterization of gene function, as biological systems are both developmental and dynamic. With such data it is possible to study gene expression changes over time and thereby to detect differential genes. Much of the early work on analyzing time series expression data relied on methods developed originally for static data and thus there is a need for improved methodology. Since time series expression is a temporal process, its unique features such as autocorrelation between successive points should be incorporated into the analysis. This work aims to identify genes that show different gene expression profiles across time. We propose a statistical procedure to discover gene groups with similar profiles using a nonparametric representation that accounts for the autocorrelation in the data. In particular, we first represent each profile in terms of a Fourier basis, and then we screen out genes that are not differentially expressed based on the Fourier coefficients. Finally, we cluster the remaining gene profiles using a model-based approach in the Fourier domain. We evaluate the screening results in terms of sensitivity, specificity, FDR and FNR, compare with the Gaussian process regression screening in a simulation study and illustrate the results by application to yeast cell-cycle microarray expression data with alpha-factor synchronization.The key elements of the proposed methodology: (i) representation of gene profiles in the Fourier domain; (ii) automatic screening of genes based on the Fourier coefficients and taking into account autocorrelation in the data, while controlling the false discovery rate (FDR); (iii) model-based clustering of the remaining gene profiles. Using this method, we identified a set of cell-cycle-regulated time-course yeast genes. The proposed method is general and can be

  1. {sup 99m}Tc sestamibi scintimammography. Screening mammographic non-palpable suspicious breast lesions: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Bekis, R.; Derebek, E.; Degirmenci, B.; Durak, H. [Dokuz Eyluel Univ., Izmir (Turkey). Dept. of Nuclear Medicine; Balci, P. [Dokuz Eyluel Univ., Izmir (Turkey). Dept. of Radiology; Kocdor, M.A. [Dokuz Eyluel Univ., Izmir (Turkey). Dept. of Surgery; Canda, T. [Dokuz Eyluel Univ., Izmir (Turkey). Dept. of Pathology

    2004-02-01

    Aim: Investigation of the diagnostic role of technetium-99m methoxyisobutylisonitrile ({sup 99m}Tc estamibi) scintimammography in non-palpable, suspicious breast lesions described as microcalcification, mass and increased density using mammography. Patients, method: 35 women with non-palpable breast lesions were enrolled in the study. Anterior, left and right lateral, ipsilateral posterior oblique images were obtained 15 min after the injection of 740 MBq of {sup 99m}Tc sestamibi. All scintigraphic images were evaluated visually and focal increased {sup 99m}Tc sestamibi uptake was accepted as malignant lesion. Breast lesions were classified as microcalcification (13 women), mammographic mass (16 women) and increased density (6 women). Excisional biopsy was performed in all of them irrespective of the scintigraphic results: Results: The focally increased {sup 99m}Tc sestamibi uptake was seen in 11 breast lesions with malignant lesions and in 4 breast lesions with benign lesions. The diffuse uptake of {sup 99m}Tc sestamibi was seen in 18 breast lesions with benign lesions and 2 breast lesions with malignant lesions. There was no false positive result of {sup 99m}Tc sestamibi in microcalcification group and three was no false negative result of the mammographic mass and increased density groups. Conclusion: Scintimammography might be a complementary method in decision making for the non-palpable, suspicious breast lesions that were evaluated as microcalcification, mass and increased density mammograpically. (orig.)

  2. Forecasting dose-time profiles of solar particle events using a dosimetry-based forecasting methodology

    Science.gov (United States)

    Neal, John Stuart

    2001-10-01

    A dosimetery-based Bayesian methodology for forecasting astronaut radiation doses in deep space due to radiologically significant solar particle event proton fluences is developed. Three non-linear sigmoidal growth curves (Gompertz, Weibull, logistic) are used with hierarchical, non-linear, regression models to forecast solar particle event dose-time profiles from doses obtained early in the development of the event. Since there are no detailed measurements of dose versus time for actual events, surrogate dose data are provided by calculational methods. Proton fluence data are used as input to the deterministic, coupled neutron-proton space radiation computer code, BRYNTRN, for transporting protons and their reaction products (protons, neutrons, 2H, 3H, 3He, and 4He) through aluminum shielding material and water. Calculated doses and dose rates for ten historical solar particle events are used as the input data by grouping similar historical solar particle events, using asymptotic dose and maximum dose rate as the grouping criteria. These historical data are then used to lend strength to predictions of dose and dose rate-time profiles for new solar particle events. Bayesian inference techniques are used to make parameter estimates and predictive forecasts. Markov Chain Monte Carlo (MCMC) methods are used to sample from the posterior distributions. Hierarchical, non-linear regression models provide useful predictions of asymptotic dose and dose-time profiles for the November 8, 2000 and August 12, 1989 solar particle events. Predicted dose rate-time profiles are adequate for the November 8, 2000 solar particle event. Predictions of dose rate-time profiles for the August 12, 1989 solar particle event suffer due to a more complex dose rate-time profile. Forecasts provide a valuable tool to space operations planners when making recommendations concerning operations in which radiological exposure might jeopardize personal safety or mission completion. This work

  3. Quantitative gene expression profiles in real time from expressed sequence tag databases.

    Science.gov (United States)

    Funari, Vincent A; Voevodski, Konstantin; Leyfer, Dimitry; Yerkes, Laura; Cramer, Donald; Tolan, Dean R

    2010-01-01

    An accumulation of expressed sequence tag (EST) data in the public domain and the availability of bioinformatic programs have made EST gene expression profiling a common practice. However, the utility and validity of using EST databases (e.g., dbEST) has been criticized, particularly for quantitative assessment of gene expression. Problems with EST sequencing errors, library construction, EST annotation, and multiple paralogs make generation of specific and sensitive qualitative arid quantitative expression profiles a concern. In addition, most EST-derived expression data exists in previously assembled databases. The Virtual Northern Blot (VNB) (http: //tlab.bu.edu/vnb.html) allows generation, evaluation, and optimization of expression profiles in real time, which is especially important for alternatively spliced, novel, or poorly characterized genes. Representative gene families with variable nucleotide sequence identity, tissue specificity, and levels of expression (bcl-xl, aldoA, and cyp2d9) are used to assess the quality of VNB's output. The profiles generated by VNB are more sensitive and specific than those constructed with ESTs listed in preindexed databases at UCSC and NCBI. Moreover, quantitative expression profiles produced by VNB are comparable to quantization obtained from Northern blots and qPCR. The VNB pipeline generates real-time gene expression profiles for single-gene queries that are both qualitatively and quantitatively reliable.

  4. The impact of time perspective latent profiles on college drinking: a multidimensional approach.

    Science.gov (United States)

    Braitman, Abby L; Henson, James M

    2015-04-01

    Zimbardo and Boyd's(1) time perspective, or the temporal framework individuals use to process information, has been shown to predict health behaviors such as alcohol use. Previous studies supported the predictive validity of individual dimensions of time perspective, with some dimensions acting as protective factors and others as risk factors. However, some studies produced findings contrary to the general body of literature. In addition, time perspective is a multidimensional construct, and the combination of perspectives may be more predictive than individual dimensions in isolation; consequently, multidimensional profiles are a more accurate measure of individual differences and more appropriate for predicting health behaviors. The current study identified naturally occurring profiles of time perspective and examined their association with risky alcohol use. Data were collected from a college student sample (n = 431, mean age = 20.41 years) using an online survey. Time perspective profiles were identified using latent profile analysis. Bootstrapped regression models identified a protective class that engaged in significantly less overall drinking (β = -0.254) as well as engaging in significantly less episodic high risk drinking (β = -0.274). There was also emerging evidence of a high risk time perspective profile that was linked to more overall drinking (β = 0.198) and engaging in more high risk drinking (β = 0.245), though these differences were not significant. CONCLUSIONS/IMPORTANCE: These findings support examining time perspective in a multidimensional framework rather than individual dimensions in isolation. Implications include identifying students most in need of interventions, and tailoring interventions to target temporal framing in decision-making.

  5. Inverse methods for estimating primary input signals from time-averaged isotope profiles

    Science.gov (United States)

    Passey, Benjamin H.; Cerling, Thure E.; Schuster, Gerard T.; Robinson, Todd F.; Roeder, Beverly L.; Krueger, Stephen K.

    2005-08-01

    Mammalian teeth are invaluable archives of ancient seasonality because they record along their growth axes an isotopic record of temporal change in environment, plant diet, and animal behavior. A major problem with the intra-tooth method is that intra-tooth isotope profiles can be extremely time-averaged compared to the actual pattern of isotopic variation experienced by the animal during tooth formation. This time-averaging is a result of the temporal and spatial characteristics of amelogenesis (tooth enamel formation), and also results from laboratory sampling. This paper develops and evaluates an inverse method for reconstructing original input signals from time-averaged intra-tooth isotope profiles. The method requires that the temporal and spatial patterns of amelogenesis are known for the specific tooth and uses a minimum length solution of the linear system Am = d, where d is the measured isotopic profile, A is a matrix describing temporal and spatial averaging during amelogenesis and sampling, and m is the input vector that is sought. Accuracy is dependent on several factors, including the total measurement error and the isotopic structure of the measured profile. The method is shown to accurately reconstruct known input signals for synthetic tooth enamel profiles and the known input signal for a rabbit that underwent controlled dietary changes. Application to carbon isotope profiles of modern hippopotamus canines reveals detailed dietary histories that are not apparent from the measured data alone. Inverse methods show promise as an effective means of dealing with the time-averaging problem in studies of intra-tooth isotopic variation.

  6. Recovery of subsurface profiles of supergranular flows via iterative inversion of synthetic travel times

    Science.gov (United States)

    Bhattacharya, Jishnu; Hanasoge, Shravan M.; Birch, Aaron C.; Gizon, Laurent

    2017-11-01

    Aims: We develop a helioseismic inversion algorithm that can be used to recover subsurface vertical profiles of two-dimensional supergranular flows from surface measurements of synthetic wave travel times. Methods: We carried out seismic wave-propagation simulations with a two-dimensional section of a flow profile that resembles an average supergranule and a starting model that only has flows at the surface. We assumed that the wave measurements are entirely without realization noise for the purpose of our test. We expanded the vertical profile of the supergranule stream function on a basis of B-splines. We iteratively updated the B-spline coefficients of the supergranule model to reduce the travel-time differences observed between the two simulations. We performed the exercise for four different vertical profiles peaking at different depths below the solar surface. Results: We are able to accurately recover depth profiles of four supergranule models at depths up to 8-10 Mm below the solar surface using f-p4 modes under the assumption that there is no realization noise. We are able to obtain the peak depth and the depth of the return flow for each model. Conclusions: A basis-resolved inversion performs significantly better than an inversion in which the flow field is inverted at each point in the radial grid. This is an encouraging result and might act as a guide in developing more realistic inversion strategies that can be applied to supergranular flows in the Sun.

  7. Identifying arsenic trioxide (ATO) functions in leukemia cells by using time series gene expression profiles.

    Science.gov (United States)

    Yang, Hong; Lin, Shan; Cui, Jingru

    2014-02-10

    Arsenic trioxide (ATO) is presently the most active single agent in the treatment of acute promyelocytic leukemia (APL). In order to explore the molecular mechanism of ATO in leukemia cells with time series, we adopted bioinformatics strategy to analyze expression changing patterns and changes in transcription regulation modules of time series genes filtered from Gene Expression Omnibus database (GSE24946). We totally screened out 1847 time series genes for subsequent analysis. The KEGG (Kyoto encyclopedia of genes and genomes) pathways enrichment analysis of these genes showed that oxidative phosphorylation and ribosome were the top 2 significantly enriched pathways. STEM software was employed to compare changing patterns of gene expression with assigned 50 expression patterns. We screened out 7 significantly enriched patterns and 4 tendency charts of time series genes. The result of Gene Ontology showed that functions of times series genes mainly distributed in profiles 41, 40, 39 and 38. Seven genes with positive regulation of cell adhesion function were enriched in profile 40, and presented the same first increased model then decreased model as profile 40. The transcription module analysis showed that they mainly involved in oxidative phosphorylation pathway and ribosome pathway. Overall, our data summarized the gene expression changes in ATO treated K562-r cell lines with time and suggested that time series genes mainly regulated cell adhesive. Furthermore, our result may provide theoretical basis of molecular biology in treating acute promyelocytic leukemia. Copyright © 2013 Elsevier B.V. All rights reserved.

  8. Microcalcificaciones mamográficas no palpables localizadas mediante colocación de arpón

    OpenAIRE

    Chávez Gallegos, José Rubén

    2013-01-01

    Objetivo: conocer la histopatología de las biopsias quirúrgicas en lesiones no palpables de mama localizadas por mamografía, luego de la colocación de arpón en la zona con microcalcificaciones. Material y métodos: la población total estuvo constituida por 136 pacientes del Hospital Nacional Guillermo Almenara Irigoyen de EsSalud, todos mayores de 40 años y sexo femenino, registrados como casos nuevos con indicación de mamografía, para descartar cáncer de mama. Las pacientes que presen...

  9. Impact of frozen storage time on the volatile profile of wheat bread crumb.

    Science.gov (United States)

    Pico, Joana; Martínez, Mario M; Bernal, José; Gómez, Manuel

    2017-10-01

    The freezing of wheat bread before aroma analyses is a common practice in order to preserve loss of the volatile profile. However, the impact of the frozen storage time on the aroma profile has not been studied. For this purpose, the volatile profiles of wheat bread frozen for 1, 2 and 4weeks were analysed employing solvent extraction and static headspace methoologies with GC/MS. The results revealed that the freezing was effective to prevent the loss of volatiles during the first week. However, after two weeks, there was an increase of volatile compounds, probably generated by chemical reactions. Thus, a maximum of one week of frozen storage was recommended when using the solvent extraction methodology. When using the static headspace method, the samples should be analysed on the same day as preparation, since the extraction was surprisingly increased due to the starch retrogradation that occurred during freezing. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. Real-time MSE measurements for current profile control on KSTARa)

    Science.gov (United States)

    De Bock, M. F. M.; Aussems, D.; Huijgen, R.; Scheffer, M.; Chung, J.

    2012-10-01

    To step up from current day fusion experiments to power producing fusion reactors, it is necessary to control long pulse, burning plasmas. Stability and confinement properties of tokamak fusion reactors are determined by the current or q profile. In order to control the q profile, it is necessary to measure it in real-time. A real-time motional Stark effect diagnostic is being developed at Korean Superconducting Tokamak for Advanced Research for this purpose. This paper focuses on 3 topics important for real-time measurements: minimize the use of ad hoc parameters, minimize external influences and a robust and fast analysis algorithm. Specifically, we have looked into extracting the retardance of the photo-elastic modulators from the signal itself, minimizing the influence of overlapping beam spectra by optimizing the optical filter design and a multi-channel, multiharmonic phase locking algorithm.

  11. Control of nanoparticle agglomeration through variation of the time-temperature profile in chemical vapor synthesis

    Science.gov (United States)

    Djenadic, Ruzica; Winterer, Markus

    2017-02-01

    The influence of the time-temperature history on the characteristics of nanoparticles such as size, degree of agglomeration, or crystallinity is investigated for chemical vapor synthesis (CVS). A simple reaction-coagulation-sintering model is used to describe the CVS process, and the results of the model are compared to experimental data. Nanocrystalline titania is used as model material. Titania nanoparticles are generated from titanium-tetraisopropoxide (TTIP) in a hot-wall reactor. Pure anatase particles and mixtures of anatase, rutile (up to 11 vol.%), and brookite (up to 29 vol.%) with primary particle sizes from 1.7 nm to 10.5 nm and agglomerate particle sizes from 24.3 nm to 55.6 nm are formed depending on the particle time-temperature history. An inductively heated furnace with variable inductor geometry is used as a novel system to control the time-temperature profile in the reactor externally covering a large wall temperature range from 873 K to 2023 K. An appropriate choice of inductor geometry, i.e. time-temperature profile, can significantly reduce the degree of agglomeration. Other particle characteristics such as crystallinity are also substantially influenced by the time-temperature profile.

  12. Control of nanoparticle agglomeration through variation of the time-temperature profile in chemical vapor synthesis

    Energy Technology Data Exchange (ETDEWEB)

    Djenadic, Ruzica; Winterer, Markus, E-mail: markus.winterer@uni-due.de [Universität Duisburg-Essen, Nanoparticle Process Technology, Faculty of Engineering and CENIDE (Germany)

    2017-02-15

    The influence of the time-temperature history on the characteristics of nanoparticles such as size, degree of agglomeration, or crystallinity is investigated for chemical vapor synthesis (CVS). A simple reaction-coagulation-sintering model is used to describe the CVS process, and the results of the model are compared to experimental data. Nanocrystalline titania is used as model material. Titania nanoparticles are generated from titanium-tetraisopropoxide (TTIP) in a hot-wall reactor. Pure anatase particles and mixtures of anatase, rutile (up to 11 vol.%), and brookite (up to 29 vol.%) with primary particle sizes from 1.7 nm to 10.5 nm and agglomerate particle sizes from 24.3 nm to 55.6 nm are formed depending on the particle time-temperature history. An inductively heated furnace with variable inductor geometry is used as a novel system to control the time-temperature profile in the reactor externally covering a large wall temperature range from 873 K to 2023 K. An appropriate choice of inductor geometry, i.e. time-temperature profile, can significantly reduce the degree of agglomeration. Other particle characteristics such as crystallinity are also substantially influenced by the time-temperature profile.

  13. Analyzing the gene expression profile of pediatric acute myeloid leukemia with real-time PCR arrays

    Directory of Open Access Journals (Sweden)

    Yan-Fang Tao

    2012-09-01

    Full Text Available Abstract Background The Real-time PCR Array System is the ideal tool for analyzing the expression of a focused panel of genes. In this study, we will analyze the gene expression profile of pediatric acute myeloid leukemia with real-time PCR arrays. Methods Real-time PCR array was designed and tested firstly. Then gene expression profile of 11 pediatric AML and 10 normal controls was analyzed with real-time PCR arrays. We analyzed the expression data with MEV (Multi Experiment View cluster software. Datasets representing genes with altered expression profile derived from cluster analyses were imported into the Ingenuity Pathway Analysis Tool. Results We designed and tested 88 real-time PCR primer pairs for a quantitative gene expression analysis of key genes involved in pediatric AML. The gene expression profile of pediatric AML is significantly different from normal control; there are 19 genes up-regulated and 25 genes down-regulated in pediatric AML. To investigate possible biological interactions of differently regulated genes, datasets representing genes with altered expression profile were imported into the Ingenuity Pathway Analysis Tool. The results revealed 12 significant networks. Of these networks, Cellular Development, Cellular Growth and Proliferation, Tumor Morphology was the highest rated network with 36 focus molecules and the significance score of 41. The IPA analysis also groups the differentially expressed genes into biological mechanisms that are related to hematological disease, cell death, cell growth and hematological system development. In the top canonical pathways, p53 and Huntington’s disease signaling came out to be the top two most significant pathways with a p value of 1.5E-8 and2.95E-7, respectively. Conclusions The present study demonstrates the gene expression profile of pediatric AML is significantly different from normal control; there are 19 genes up-regulated and 25 genes down-regulated in pediatric AML. We

  14. Analyzing the gene expression profile of pediatric acute myeloid leukemia with real-time PCR arrays.

    Science.gov (United States)

    Yan-Fang, Tao; Dong, Wu; Li, Pang; Wen-Li, Zhao; Jun, Lu; Na, Wang; Jian, Wang; Xing, Feng; Yan-Hong, Li; Jian, Ni; Jian, Pan

    2012-09-08

    The Real-time PCR Array System is the ideal tool for analyzing the expression of a focused panel of genes. In this study, we will analyze the gene expression profile of pediatric acute myeloid leukemia with real-time PCR arrays. Real-time PCR array was designed and tested firstly. Then gene expression profile of 11 pediatric AML and 10 normal controls was analyzed with real-time PCR arrays. We analyzed the expression data with MEV (Multi Experiment View) cluster software. Datasets representing genes with altered expression profile derived from cluster analyses were imported into the Ingenuity Pathway Analysis Tool. We designed and tested 88 real-time PCR primer pairs for a quantitative gene expression analysis of key genes involved in pediatric AML. The gene expression profile of pediatric AML is significantly different from normal control; there are 19 genes up-regulated and 25 genes down-regulated in pediatric AML. To investigate possible biological interactions of differently regulated genes, datasets representing genes with altered expression profile were imported into the Ingenuity Pathway Analysis Tool. The results revealed 12 significant networks. Of these networks, Cellular Development, Cellular Growth and Proliferation, Tumor Morphology was the highest rated network with 36 focus molecules and the significance score of 41. The IPA analysis also groups the differentially expressed genes into biological mechanisms that are related to hematological disease, cell death, cell growth and hematological system development. In the top canonical pathways, p53 and Huntington's disease signaling came out to be the top two most significant pathways with a p value of 1.5E-8 and2.95E-7, respectively. The present study demonstrates the gene expression profile of pediatric AML is significantly different from normal control; there are 19 genes up-regulated and 25 genes down-regulated in pediatric AML. We found some genes dyes-regulated in pediatric AML for the first time as

  15. Correlation between Fine-Needle Aspiration Cytology and Histology for Palpable Breast Masses in a Nigerian Tertiary Health Institution

    Directory of Open Access Journals (Sweden)

    Adetola Olubunmi Daramola

    2015-01-01

    Full Text Available Background. Management of breast lumps can be challenging in resource poor settings. Fine-needle aspiration cytology (FNAC especially when used with cell block can help improve affordability for the patients. Objective. To determine the diagnostic accuracy of FNAC of palpable breast lesions within a 5-year period. Methods. The findings obtained from FNAC of palpable breast lumps seen at the FNAC clinic of our department from January 2007 to December 2011 were retrieved and correlated with findings on histology of excisional biopsies. Results. A total of 1790 patients had FNAC of breast lumps during the 5-year period; 436 of them subsequently had biopsies. Our results compare favourably with the measures of test performance of the UK NHS Breast Screening Programme shown in brackets: absolute sensitivity 95.4% (>70%, complete sensitivity 99.2% (>90%, full specificity 88.9% (>65%, positive predictive value 99.6% (>99%, false-negative rate 0.8% (<4%, false-positive rate 0.4% (<0.5%, inadequate rate 3.2% (<15%, and suspicious rate 10.2% (<15%. Conclusion. Breast FNACs compare very well with histology of excisional biopsies and in experienced hands are extremely useful in the management of breast lumps. Further studies assessing the diagnostic accuracy of FNAC and cell blocks in our setting are recommended.

  16. An original approach in the diagnosis of early breast cancer: use of the same radiopharmaceutical for both non-palpable lesions and sentinel node localisation

    Energy Technology Data Exchange (ETDEWEB)

    Feggi, L.; Prandini, N. [Dept. of Nuclear Medicine, S. Anna Hospital, Ferrara (Italy); Basaglia, E.; Soliani, G.; Ascanelli, S.; Bergossi, L.; Carcoforo, P. [Dept. of General Surgery, University of Ferrara (Italy); Corcione, S. [Dept. of Radiology, S. Anna Hospital, Ferrara (Italy); Querzoli, P. [Dept. of Pathology, Univ. of Ferrara (Italy)

    2001-11-01

    We propose the use of a single nanocolloid tracer which is labelled with technetium-99m for simultaneous performance of ROLL and sentinel node indentification. The aim of this study was to evaluate the feasibility of this approach, which should be easier and more practical than the dual-tracer injection method. We have employed this new technique in 73 patients with non-palpable, cytologically diagnosed breast cancer and non-palpable axillary lymph nodes. In all patients the radiocolloid, in a total volume of 0.3-0.4 cc, was injected under sonographic or stereotactic guidance. Half of the dose was injected intratumourally and half superficially, but very close to the tumour. Because of the slow lymphatic flow in the breast, Nanocoll must be injected some time before surgery in order to enable adequate migration to the axilla. We injected colloid in the afternoon before surgery (16-23 h before the start of the operation, with an average interval of 18 h). An average dose of 130 MBq (range 110-150) was injected in order to have about 10 MBq of radioactivity when surgery commenced. Lymphoscintigraphy was performed after 15-19 h, with an average interval of 17 h. The procedure was always successful in permitting the localisation of occult breast lesions. Lesions were always localised at the first attempt, and were always contained within the surgical margins. Histological examination revealed all 73 resected lesions to be malignant: there were 64 cases of infiltrating carcinoma and nine of intraductal carcinoma. All breast lesions were therefore confirmed to be early breast cancer. We achieved sentinel node localisation in 71 out of 73, either at scintigraphy or with the intraoperative probe; in two patients, radiopharmaceutical migration was absent. Lymphoscintigraphy showed only axillary drainage in 52 cases, only internal mammary chain (IMC) drainage in nine cases, and combined axillary and IMC drainage in eight cases. In two cases, lymphoscintigraphy suggested the

  17. Evaluation of time-accelerated irradiation method of elastomer by modulus-ultimate elongation profile

    Energy Technology Data Exchange (ETDEWEB)

    Ito, Masayuki [Waseda University Faculty of Science and Engineering, 3-4-1 Ookubo, Shinjuku-ku, Tokyo 169-8555 (Japan)], E-mail: masayuki@kurenai.waseda.jp; Oka, Toshitaka; Hama, Yosimasa [Waseda University Faculty of Science and Engineering, 3-4-1 Ookubo, Shinjuku-ku, Tokyo 169-8555 (Japan)

    2009-12-15

    'Generalized modulus-ultimate elongation profile' was induced from the relationship between the modulus and the ultimate elongation of an elastomer that was quantitatively added crosslinking and scission. This profile can be used to evaluate the time-accelerated irradiation methods of ethylene-propylene-diene elastomer. The irradiation under low dose rate (0.33 kGy/h) at room temperature was the reference condition. The short-time irradiation condition was 4.2 kGy/h in 0.5 MPa oxygen at room temperature and 5.0 kGy/h in air at 70 {sup o}C. The former tended to bring about the higher ratio of scission than the reference condition; the latter tended to bring about the higher ratio of crosslinking.

  18. Experimental estimation of the photons visiting probability profiles in time-resolved diffuse reflectance measurement.

    Science.gov (United States)

    Sawosz, P; Kacprzak, M; Weigl, W; Borowska-Solonynko, A; Krajewski, P; Zolek, N; Ciszek, B; Maniewski, R; Liebert, A

    2012-12-07

    A time-gated intensified CCD camera was applied for time-resolved imaging of light penetrating in an optically turbid medium. Spatial distributions of light penetration probability in the plane perpendicular to the axes of the source and the detector were determined at different source positions. Furthermore, visiting probability profiles of diffuse reflectance measurement were obtained by the convolution of the light penetration distributions recorded at different source positions. Experiments were carried out on homogeneous phantoms, more realistic two-layered tissue phantoms based on the human skull filled with Intralipid-ink solution and on cadavers. It was noted that the photons visiting probability profiles depend strongly on the source-detector separation, the delay between the laser pulse and the photons collection window and the complex tissue composition of the human head.

  19. Thermonuclear supernovae: probing magnetic fields by positrons and late-time IR line profiles

    Energy Technology Data Exchange (ETDEWEB)

    Penney, R.; Hoeflich, P., E-mail: phoeflich77@gmail.com, E-mail: rpenney@g.clemson.edu [Department of Physics, Florida State University, Tallahassee, FL 32305 (United States)

    2014-11-01

    We show the importance of γ and positron transport for the formation of late-time spectra in Type Ia supernovae (SNe Ia). The goal is to study the imprint of magnetic fields (B) on late-time IR line profiles, particularly the [Fe II] feature at 1.644 μm, which becomes prominent two to three months after the explosion. As a benchmark, we use the explosion of a Chandrasekhar mass (M {sub Ch}) white dwarf (WD) and, specifically, a delayed detonation model that can reproduce the light curves and spectra for a Branch-normal SN Ia. We assume WDs with initial magnetic surface fields between 1 and 10{sup 9} G. We discuss large-scale dipole and small-scale magnetic fields. We show that positron transport effects must be taken into account for the interpretation of emission features starting at about one to two years after maximum light, depending on the size of B. The [Fe II] line profile and its evolution with time can be understood in terms of the overall energy input by radioactive decay and the transition from a γ-ray to a positron-dominated regime. We find that the [Fe II] line at 1.644 μm can be used to analyze the overall chemical and density structure of the exploding WD up to day 200 without considering B. At later times, positron transport and magnetic field effects become important. After about day 300, the line profile allows one to probe the size of the B-field. The profile becomes sensitive to the morphology of B at about day 500. In the presence of a large-scale dipole field, a broad line is produced in M {sub Ch} mass explosions that may appear flat-topped or rounded depending on the inclination at which the SN is observed. Small or no directional dependence of the spectra is found for small-scale B. We note that narrow-line profiles require central {sup 56}Ni as shown in our previous studies. Persistent broad-line, flat-topped profiles require high-density burning, which is the signature of a WD close to M {sub Ch}. Good time coverage is required to

  20. More than just physical activity: time use clusters and profiles of Australian youth.

    Science.gov (United States)

    Ferrar, Katia; Olds, Tim; Maher, Carol

    2013-09-01

    To describe time use clusters and correlate-cluster profiles of Australian youth. Secondary analysis of cross-sectional national survey. Data were from the National Children's Nutrition and Physical Activity Survey, a random sample (n=1853) of 9-16 years old Australians (February-August 2007). Time use data were collected using the Multimedia Activity Recall for Children and Adults, and collapsed into 17 age-adjusted variables for sex-specific cluster analysis. Cluster associations with socio-demographic, anthropometric, health and dietary variables were analysed. For boys (n=930), the Social tasker cluster was characterised by social interaction and chores & work, the Techno-active cluster by team sport and TV and the Techno-studious cluster by video games and study. Average daily pedometer steps, age and remoteness were significant cluster correlates. For the girls (n=923), the Social screenie cluster was characterised by TV and social interaction, the Quiet actives cluster by quiet time and non-team sport and the Techno-studious cluster by video games and study. Pedometer steps, age, parental income and education, parent-child age difference, "extra foods", fat and fruit intakes were significant correlates. Distinct sex-specific time use clusters and profiles exist among Australian youth. These findings may assist the development of targeted time use interventions to improve health and well-being. Copyright © 2012 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  1. Time-intensity profile of pitanga nectar (Eugenia uniflora L.) with different sweeteners: Sweetness and bitterness.

    Science.gov (United States)

    Freitas, Mírian Luisa Faria; de Lima Dutra, Mariana Borges; Bolini, Helena Maria André

    2016-01-01

    Pitanga has been used by the Brazilian food industry mainly for juice production. This fruit shows good economic potential due to its high concentration of vitamins and minerals. The aim of the present work was to characterize the time-intensity profile of pitanga nectar sweetened with different sweeteners to verify differences on the perception of sweet and bitter tastes. The sweeteners used to replace sucrose were sucralose, aspartame, stevia 40% rebaudioside A, stevia 95% rebaudioside A, neotame, and 2:1 cyclamate/saccharin blend. Fifteen assessors were selected according to their discriminating capability and trained to participate in the time-intensity analysis for sweetness and bitterness. The samples prepared with sucralose and 2:1 cyclamate/saccharin blend presented a similar sweetness profile to the sample prepared with sucrose, and the samples prepared with sucralose and aspartame presented a similar bitterness profile to the sample prepared with sucrose. Thus, sucralose would be the most suitable sweetener to replace sucrose in pitanga nectar. © The Author(s) 2015.

  2. Consistency of time dilation in temporal profiles and spectra of gamma-ray bursts

    Science.gov (United States)

    Noriss, J. P.; Nemiroff, R. J.; Bonnell, J. T.; Scargle, J. D.; Davis, S. P.; Kouveliotou, C.; Pendleton, G.; Fishman, G. J.; Meegan, C. A.; Paciesas, W. S.

    1995-01-01

    If gamma-ray bursters are at cosmological distances-a possibility suggested by their isotropic distribution and spatial inhomogeneity-then the temporal profiles and spectra of more distant sources will be time dilated compared to those of relatively nearby sources. Analyses of bright and dim Burst and Transient Source Experiment (BATSE) gamma-ray bursts yield a relative time-dilation factor of 2.3 on timescales of pulses and event durations. We redshift the spectra of time intervals near the intensity peaks of the bright sample on a trial grid and compare with spectra of the dim sample. A redshift factor of order two-with wide latitude permitted-brings the spectra of the two brightness groups into alignment. Thus there is coarse agreement with the time-dilation factor found in the temporal domain.

  3. Real-time monitoring of incision profile during laser surgery using shock wave detection.

    Science.gov (United States)

    Bay, Erwin; Deán-Ben, Xosé Luís; Pang, Genny A; Douplik, Alexandre; Razansky, Daniel

    2015-01-01

    Lack of sensory feedback during laser surgery prevents surgeons from discerning the exact location of the incision, which increases duration and complexity of the treatment. In this study we demonstrate a new method for monitoring of laser ablation procedures. Real-time tracking of the exact three dimensional (3D) lesion profile is accomplished by detection of shock waves emanating from the ablation spot and subsequent reconstruction of the incision location using time-of-flight data obtained from multiple acoustic detectors. Here, incisions of up to 9 mm in depth, created by pulsed laser ablation of fresh bovine tissue samples, were successfully monitored in real time. It was further observed that, by utilizing as little as 12 detection elements, the incision profile can be characterized with accuracy below 0.5 mm in all three dimensions and in good agreement with histological examinations. The proposed method holds therefore promise for delivering high precision real-time feedback during laser surgeries. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  4. Time place learning and activity profile under constant light and constant dark in zebrafish (Danio rerio).

    Science.gov (United States)

    Moura, Clarissa de Almeida; Lima, Jéssica Polyana da Silva; Silveira, Vanessa Augusta Magalhães; Miguel, Mário André Leocadio; Luchiari, Ana Carolina

    2017-05-01

    The ability to learn about the signs of variability in space and time is known as time place learning (TPL). To adjust their circadian rhythms, animals use stimuli that change regularly, such as the light-dark cycle, temperature, food availability or even social stimuli. Because light-dark cycle is the most important environmental temporal cue, we asked how a diurnal animal would perform TPL if this cue was removed. Zebrafish has been extensively studied in the chronobiology area due to it diurnal chronotype, thus, we studied the effects of constant light and constant dark on the time-place learning and activity profile in zebrafish. Our data show that while under constant light and dark condition zebrafish was not able of TPL, after 30days under the constant conditions, constant light led to higher activity level and less significant (robust) 24h rhythm. Copyright © 2017 Elsevier B.V. All rights reserved.

  5. Development of a Rapid Beam Emittance Measurement System using a Real-Time Beam Profile Monitor

    Science.gov (United States)

    Kamakura, Keita; Hatanaka, Kichiji; Fukuda, Mitsuhiro; Yorita, Tetsuhiko; Ueda, Hiroshi; Saito, Takane; Morinobu, Shunpei; Nagayama, Keiichi; Tamura, Hitoshi; Yasuda, Yuusuke

    2016-06-01

    We have developed a rapid beam emittance measurement system for the injection beam of the K140 azimuthally varying field (AVF) cyclotron at Research Center for Nuclear Physics (RCNP). So far, a conventional emittance monitor has been used in a section of a medium energy beam transport (MEBT) system to evaluate the quality of the injected beam to the K400 ring cyclotron. Two kinds of emittance monitors were supplemented in the low energy beam line for evaluation of ion beams from ion sources. One of them is a conventional type consisting of two sets of position-variable slits and a three-wire profile monitor (TPM), similar to the one installed in the MEBT system of the AVF cyclotron. It takes about 30 min to get emittances in both the horizontal and vertical planes. For quick emittance measurements, we have developed a new system equipped with a set of fast moving slits with a fixed gap and a real-time beam profile monitor (BPM83) with a rotating helical wire. With this system the measurement time was considerably reduced to 70 s for both the horizontal and vertical emittances. Moreover the data analysis and graphical processing were completely automated. The overall measurement and analysis time was successfully minimized within 75 s. This rapid emittance measurement system has contributed to improve the beam quality by optimizing parameters of ion sources and the beam transport system.

  6. Time-Domain Techniques for Computation and Reconstruction of One-Dimensional Profiles

    Directory of Open Access Journals (Sweden)

    M. Rahman

    2005-01-01

    Full Text Available This paper presents a time-domain technique to compute the electromagnetic fields and to reconstruct the permittivity profile within a one-dimensional medium of finite length. The medium is characterized by a permittivity as well as conductivity profile which vary only with depth. The discussed scattering problem is thus one-dimensional. The modeling tool is divided into two different schemes which are named as the forward solver and the inverse solver. The task of the forward solver is to compute the internal fields of the specimen which is performed by Green’s function approach. When a known electromagnetic wave is incident normally on the media, the resulting electromagnetic field within the media can be calculated by constructing a Green’s operator. This operator maps the incident field on either side of the medium to the field at an arbitrary observation point. It is nothing but a matrix of integral operators with kernels satisfying known partial differential equations. The reflection and transmission behavior of the medium is also determined from the boundary values of the Green's operator. The inverse solver is responsible for solving an inverse scattering problem by reconstructing the permittivity profile of the medium. Though it is possible to use several algorithms to solve this problem, the invariant embedding method, also known as the layer-stripping method, has been implemented here due to the advantage that it requires a finite time trace of reflection data. Here only one round trip of reflection data is used, where one round trip is defined by the time required by the pulse to propagate through the medium and back again. The inversion process begins by retrieving the reflection kernel from the reflected wave data by simply using a deconvolution technique. The rest of the task can easily be performed by applying a numerical approach to determine different profile parameters. Both the solvers have been found to have the

  7. Inference of biological pathway from gene expression profiles by time delay boolean networks.

    Directory of Open Access Journals (Sweden)

    Tung-Hung Chueh

    Full Text Available One great challenge of genomic research is to efficiently and accurately identify complex gene regulatory networks. The development of high-throughput technologies provides numerous experimental data such as DNA sequences, protein sequence, and RNA expression profiles makes it possible to study interactions and regulations among genes or other substance in an organism. However, it is crucial to make inference of genetic regulatory networks from gene expression profiles and protein interaction data for systems biology. This study will develop a new approach to reconstruct time delay boolean networks as a tool for exploring biological pathways. In the inference strategy, we will compare all pairs of input genes in those basic relationships by their corresponding p-scores for every output gene. Then, we will combine those consistent relationships to reveal the most probable relationship and reconstruct the genetic network. Specifically, we will prove that O(log n state transition pairs are sufficient and necessary to reconstruct the time delay boolean network of n nodes with high accuracy if the number of input genes to each gene is bounded. We also have implemented this method on simulated and empirical yeast gene expression data sets. The test results show that this proposed method is extensible for realistic networks.

  8. Clustering Finnish Gambler Profiles Based on the Money and Time Consumed in Gambling Activities.

    Science.gov (United States)

    Heiskanen, Maria; Toikka, Arho

    2016-06-01

    Gambling involves consumption of gamblers' money and time. Gamblers are a heterogeneous group, and in addition to grouping gamblers based on personality factors, it is also important to find different gambler profiles with respect to their gambling behavior. Using the nationally representative survey 'Finnish Gambling 2011' (N = 4484), this article studies the subtypes of Finnish gamblers based on the frequency of gambling and the amounts of money and time used in different gambling forms. Cluster analysis reveals six profiles of gamblers, from infrequent gamblers to omnivorous gamblers. In the further analysis of the clusters, it was found that the highest problem gambling prevalence was in the groups of sport betting + electronic gaming machine gamblers and omnivorous gamblers, which were also both dominated by men. Certain gambling consumption patterns and risk factors for problem gambling are related to both socio-demographic backgrounds of the gamblers as well as the structural and situational characteristics of the games. The results have implications for the prevention of problem gambling, as some consumption patterns may be connected with the probability of developing gambling problems.

  9. Impact of roasting time on the sensory profile of arabica and robusta coffee.

    Science.gov (United States)

    Bicho, Natalina Cavaco; Leitão, António Eduardo; Ramalho, José Cochicho; de Alvarenga, Nuno Bartolomeu; Lidon, Fernando Cebola

    2013-01-01

    Roasted coffee samples of the two major trade species (Coffea arabica and C. canephora) were studied to identify sensory descriptors that might be used to determine blends production and evaluation, following the expectations of consumers. Coffee beans were roasted at 220 + 10 °C, for 7, 9, and 11 min, and the sensory profiles of the beverages were assessed. From descriptive analysis the eigenvalues allowed the identification of two principal components (PCs), being the variance between samples 68.9% and 21.1%. In the first PC the characteristic odor, astringency, body, bitter flavor, burned aroma, and residual, typical, and burned tastes prevailed. The correlation coefficient between the second PC and citric acid flavor and aroma reached 0.96 and 0.78, respectively. It was concluded that in beverages of these species, the descriptors of both components can be separated according to bean roasting time. Considering roasting time, the overall quality was also rated.

  10. Application of Localization and Needle Placement Guided by Mammographic, Ultrasound and Fiberoptic Ductoscopy for Resection of Non-palpable Breast Lesions.

    Science.gov (United States)

    Yuan, Zhu; Qu, Xiang; Zhang, Zhong-Tao; Jiang, Wen G

    2017-08-01

    To evaluate the usefulness of localization needles under mammographic, ultrasound or fiberoptic ductoscopy guidance for non-palpable breast lesions. Eighty-three patients undergoing needle localization and biopsy of non-palpable breast lesions under mammographic, ultrasound or fiberoptic ductoscopy guidance from June 2013 to December 2014 in Beijing Friendship Hospital were included in the study. The preoperative imaging assessment, application of localization needles, surgical operation and pathological examination were recorded and analyzed retrospectively. A total of 83 localization and biopsies were carried out, of which 27 were performed under mammographic guidance, 32 under ultrasound guidance and 24 under fiberoptic ductoscopy guidance. Twenty-seven cases of breast microcalcifications were localized under mammographic guidance and surgically removed, of which eight cases were pathologically diagnosed as malignant. Thirty-two cases of non-palpable breast lesions were localized under ultrasound guidance and 30 pathologically diagnosed, of these, four cases were pathologically diagnosed as malignant. Twenty-four cases of intraductal space-occupying lesions were localized under ductoscopy guidance and surgically removed, of which five cases were pathologically diagnosed as malignant. Utilization of localization needles under mammographic, ultrasound or fiberoptic ductoscopy guidance for non-palpable breast lesions is a safe and effective procedure, and is helpful in the diagnosis of breast cancer. With the help of this procedure, more malignant lesions can be localized and surgically removed. Copyright© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

  11. Screening for thyroid cancer according to French recommendations with thyroid ultrasound in newly diagnosed Graves' disease without palpable nodule is not useful.

    Science.gov (United States)

    Nys, Pierre; Cordray, Jean-Pierre; Sarafian, Véronique; Lefort-Mossé, Ève; Merceron, Robert-Édouard

    2015-02-01

    The aim of the study was to evaluate systematic thyroid ultrasonography (US) relevance in newly diagnosed Graves' disease among patients presenting without palpable nodules. We consecutively recruited 208 cases of Graves' disease without palpable nodule. All patients were screened for thyroid antibodies and underwent a thyroid US. Ultrasonically guided biopsy was proposed for the assessment of all nodules upper or equal to 10mm in diameter. Two third of patients had an abnormal thyroid at palpation requiring an US. One third of patients had a normal thyroid at palpation and US was consequently unwarranted. Among all patients, US detected non-palpable nodules in 26% of cases. We found no smears suspected to be cancerous. In newly diagnosed Graves' disease, the US relevance is only questionable in patients without abnormal thyroid at palpation. Ultrasonography detected non-palpable nodules and none was suspected to be cancerous. These data suggest that US is not useful in patients without abnormal thyroid at palpation. Nevertheless, the recent Thyroid Imaging-Reporting And Data System classification (TI-RADS) might change our conclusions. The TI-RADS classification indeed improves the selection of nodules lower than 10mm in diameter requiring a biopsy. Nodules lower than 10mm in diameter were not biopsied in the present study. The other US data presented herein (echogenicity, vascularisation) provide no further relevance for systematic US in newly diagnosed patients. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  12. Storage time does not modify the gene expression profile of cryopreserved human metaphase II oocytes.

    Science.gov (United States)

    Stigliani, Sara; Moretti, Stefano; Anserini, Paola; Casciano, Ida; Venturini, Pier Luigi; Scaruffi, Paola

    2015-11-01

    Does storage time have any impact on the transcriptome of slowly frozen cryopreserved human metaphase II (MII) oocytes? The length of cryostorage has no effect on the gene expression profile of human MII oocytes. Oocyte cryopreservation is a widely used technique in IVF for storage of surplus oocytes, as well as for fertility preservation (i.e. women undergoing gonadotoxic therapies) and oocyte donation programs. Although cryopreservation has negative impacts on oocyte physiology and it is associated with decrease of transcripts, no experimental data about the effect of storage time on the oocyte molecular profile are available to date. This study included 27 women, ≤38 years aged, without any ovarian pathology, undergoing IVF treatment. Surplus MII oocytes were donated after written informed consent. A total of 31 non-cryopreserved oocytes and 68 surviving slow-frozen/rapid-thawed oocytes (32 oocytes cryostored for 3 years and 36 cryostored for 6 years) were analyzed. Pools of ≈10 oocytes for each group were prepared. Total RNA was extracted from each pool, amplified, labeled and hybridized on oligonucleotide microarrays. Analyses were performed by R software using the limma package. Comparison of gene expression profiles between surviving thawed oocytes after 3 and 6 years of storage in liquid nitrogen found no differently expressed genes. The expression profiles of cryopreserved MII oocytes significantly differed from those of non-cryopreserved oocytes in 107 probe sets corresponding to 73 down-regulated and 29 up-regulated unique transcripts. Gene Ontology analysis by DAVID bioinformatics resource disclosed that cryopreservation deregulates genes involved in oocyte function and early embryo development, such as chromosome organization, RNA splicing and processing, cell cycle, cellular response to DNA damage and to stress, DNA repair, calcium ion binding, malate dehydrogenase activity and mitochondrial activity. Among the probes significantly up-regulated in

  13. Full-time employed and a family caregiver: a profile of women's workload, effort, and health.

    Science.gov (United States)

    Juratovac, Evanne; Zauszniewski, Jaclene A

    2014-01-01

    Women provide care for elderly family members while managing their other responsibilities, including full-time employment. This descriptive study used an inductively derived workload-effort-health theoretical model to examine workload, effort, and health among 46 full-time employed family caregivers [CG] of community-dwelling older adults from a larger, nonprobability, cross-sectional sample of 110 CGs. The women's caregiving workload (time, difficulty, care recipient's [CR] function), effort (perceived exertion of energy experienced in doing a workload), self-assessed health [SAH], depressive symptoms, and sources of help were richly described, and several associations were found, including higher physical and mental effort, were significantly correlated with higher workload time and difficulty and lower CR function, but not SAH. Higher mental effort and workload, and poorer SAH were significantly correlated with high depressive symptoms. Worse effort, workload, and health experiences were reported by daughters and by women who lived with their CR; those who did not have family or formal caregiving help had higher mental effort and were more depressed, suggesting an area for further study. Suggestions are offered for richer measurement of employment status, caregiving workload, and effort. Findings provide a unique profile of full-time employed women CGs' workload, effort (that is, how they do the work), and health, toward a stronger understanding of how women manage multiple workloads. Workplace policies are needed to address workload, effort and health in this informal caregiving workforce. Copyright © 2014 Jacobs Institute of Women's Health. Published by Elsevier Inc. All rights reserved.

  14. A real time metabolomic profiling approach to detecting fish fraud using rapid evaporative ionisation mass spectrometry.

    Science.gov (United States)

    Black, Connor; Chevallier, Olivier P; Haughey, Simon A; Balog, Julia; Stead, Sara; Pringle, Steven D; Riina, Maria V; Martucci, Francesca; Acutis, Pier L; Morris, Mike; Nikolopoulos, Dimitrios S; Takats, Zoltan; Elliott, Christopher T

    2017-01-01

    Fish fraud detection is mainly carried out using a genomic profiling approach requiring long and complex sample preparations and assay running times. Rapid evaporative ionisation mass spectrometry (REIMS) can circumvent these issues without sacrificing a loss in the quality of results. To demonstrate that REIMS can be used as a fast profiling technique capable of achieving accurate species identification without the need for any sample preparation. Additionally, we wanted to demonstrate that other aspects of fish fraud other than speciation are detectable using REIMS. 478 samples of five different white fish species were subjected to REIMS analysis using an electrosurgical knife. Each sample was cut 8-12 times with each one lasting 3-5 s and chemometric models were generated based on the mass range m/z 600-950 of each sample. The identification of 99 validation samples provided a 98.99% correct classification in which species identification was obtained near-instantaneously (≈ 2 s) unlike any other form of food fraud analysis. Significant time comparisons between REIMS and polymerase chain reaction (PCR) were observed when analysing 6 mislabelled samples demonstrating how REIMS can be used as a complimentary technique to detect fish fraud. Additionally, we have demonstrated that the catch method of fish products is capable of detection using REIMS, a concept never previously reported. REIMS has been proven to be an innovative technique to help aid the detection of fish fraud and has the potential to be utilised by fisheries to conduct their own quality control (QC) checks for fast accurate results.

  15. The Validation of Version 8 Ozone Profiles: Is SBUV Ready for Prime Time?

    Science.gov (United States)

    McPeters, R. D.; Wellemeyer, C. G.; Ahn, C.

    2004-01-01

    Ozone profile data are now available from a series of BUV instruments - SBUV on Nimbus 7 and SBW/2 instruments on NOAA 9, NOAA 11, and NOAA 16. The data have been processed through the new version 8 algorithm, which is designed to be more accurate and, more importantly, to reduce the influence of the a priori on ozone trends. As a part of the version 8 reprocessing we have attempted to apply a consistent calibration to the individual instruments so that their data records can be used together in a time series analysis. Validation consists of examining not only the mean difference from external datasets (i.e trends) but also consistency in the interannual variability of the data. Here we validate the v8 BUV data through comparison with ECC sondes, lidar and microwave measurements, and with SAGE II and HALOE satellite data records. We find that individual profiles generally agree with external data sets within +/-10% between 30 hPa and 1 hPa (approx. 24 - 50 km) and frequently agree within +/-5%. The interannual variability of the BUV ozone time series agrees well with that of SAGE II . On the average, different B W instruments usually agree within +/-5% with each other, though the relative error increases near the ends of the Nimbus 7 and NOAA 16 data records as a result of instrument problems. The combined v8 BUV data sets cover the 1979-2003 time period giving daily global coverage of the ozone vertical distribution to better accuracy than has ever been possible before.

  16. EDISA: extracting biclusters from multiple time-series of gene expression profiles

    Directory of Open Access Journals (Sweden)

    Harter Klaus

    2007-09-01

    Full Text Available Abstract Background Cells dynamically adapt their gene expression patterns in response to various stimuli. This response is orchestrated into a number of gene expression modules consisting of co-regulated genes. A growing pool of publicly available microarray datasets allows the identification of modules by monitoring expression changes over time. These time-series datasets can be searched for gene expression modules by one of the many clustering methods published to date. For an integrative analysis, several time-series datasets can be joined into a three-dimensional gene-condition-time dataset, to which standard clustering or biclustering methods are, however, not applicable. We thus devise a probabilistic clustering algorithm for gene-condition-time datasets. Results In this work, we present the EDISA (Extended Dimension Iterative Signature Algorithm, a novel probabilistic clustering approach for 3D gene-condition-time datasets. Based on mathematical definitions of gene expression modules, the EDISA samples initial modules from the dataset which are then refined by removing genes and conditions until they comply with the module definition. A subsequent extension step ensures gene and condition maximality. We applied the algorithm to a synthetic dataset and were able to successfully recover the implanted modules over a range of background noise intensities. Analysis of microarray datasets has lead us to define three biologically relevant module types: 1 We found modules with independent response profiles to be the most prevalent ones. These modules comprise genes which are co-regulated under several conditions, yet with a different response pattern under each condition. 2 Coherent modules with similar responses under all conditions occurred frequently, too, and were often contained within these modules. 3 A third module type, which covers a response specific to a single condition was also detected, but rarely. All of these modules are

  17. Gene set differential analysis of time course expression profiles via sparse estimation in functional logistic model with application to time-dependent biomarker detection.

    Science.gov (United States)

    Kayano, Mitsunori; Matsui, Hidetoshi; Yamaguchi, Rui; Imoto, Seiya; Miyano, Satoru

    2016-04-01

    High-throughput time course expression profiles have been available in the last decade due to developments in measurement techniques and devices. Functional data analysis, which treats smoothed curves instead of originally observed discrete data, is effective for the time course expression profiles in terms of dimension reduction, robustness, and applicability to data measured at small and irregularly spaced time points. However, the statistical method of differential analysis for time course expression profiles has not been well established. We propose a functional logistic model based on elastic net regularization (F-Logistic) in order to identify the genes with dynamic alterations in case/control study. We employ a mixed model as a smoothing method to obtain functional data; then F-Logistic is applied to time course profiles measured at small and irregularly spaced time points. We evaluate the performance of F-Logistic in comparison with another functional data approach, i.e. functional ANOVA test (F-ANOVA), by applying the methods to real and synthetic time course data sets. The real data sets consist of the time course gene expression profiles for long-term effects of recombinant interferon β on disease progression in multiple sclerosis. F-Logistic distinguishes dynamic alterations, which cannot be found by competitive approaches such as F-ANOVA, in case/control study based on time course expression profiles. F-Logistic is effective for time-dependent biomarker detection, diagnosis, and therapy. © The Author 2015. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  18. A new beam profile monitor and time of flight system for CologneAMS

    Energy Technology Data Exchange (ETDEWEB)

    Pascovici, G. [CologneAMS, University of Cologne (Germany); Dewald, A., E-mail: dewald@ikp.uni-koeln.de [CologneAMS, University of Cologne (Germany); Institute of Nuclear Physics, University of Cologne (Germany); Heinze, S., E-mail: heinze@ikp.uni-koeln.de [CologneAMS, University of Cologne (Germany); Fink, L.; Mueller-Gatermann, C.; Schiffer, M.; Feuerstein, C. [CologneAMS, University of Cologne (Germany); Pfeiffer, M.; Jolie, J.; Thiel, S.; Zell, K.O.; Arnopolina, O. [Institute of Nuclear Physics, University of Cologne (Germany); Blanckenburg, F. von [GFZ, German Research Centre for Geosciences, Potsdam (Germany)

    2013-01-15

    A complex beam detector consisting of a high-resolution beam profile monitor (BPM) and a time of flight (TOF) spectrometer with tracking capabilities was designed especially for the special needs of the Cologne center for accelerator mass spectrometry (CologneAMS). The beam detector assembly is designed to match the beam specifications of the 6 MV Tandetron AMS setup and its data acquisition system. It will have a reconfigurable structure, either as a fast TOF subsystem with a ca. 10 cm{sup 2} equivalent active area, or as a more complex BPM-TOF detector with beam tracking capabilities and a larger active area (16 cm{sup 2}). The purpose of this detector is to suppress background during spectrometry of heavy ions (U, Cm, Pu, Am etc.) and to suppress isobaric interferences such as {sup 36}S in {sup 36}Cl spectra.

  19. Time-varying Entry Heating Profile Replication with a Rotating Arc Jet Test Article

    Science.gov (United States)

    Grinstead, Jay Henderson; Venkatapathy, Ethiraj; Noyes, Eric A.; Mach, Jeffrey J.; Empey, Daniel M.; White, Todd R.

    2014-01-01

    A new approach for arc jet testing of thermal protection materials at conditions approximating the time-varying conditions of atmospheric entry was developed and demonstrated. The approach relies upon the spatial variation of heat flux and pressure over a cylindrical test model. By slowly rotating a cylindrical arc jet test model during exposure to an arc jet stream, each point on the test model will experience constantly changing applied heat flux. The predicted temporal profile of heat flux at a point on a vehicle can be replicated by rotating the cylinder at a prescribed speed and direction. An electromechanical test model mechanism was designed, built, and operated during an arc jet test to demonstrate the technique.

  20. Development of an ion time-of-flight spectrometer for neutron depth profiling

    Science.gov (United States)

    Cetiner, Mustafa Sacit

    Ion time-of-flight spectrometry techniques are investigated for applicability to neutron depth profiling. Time-of-flight techniques are used extensively in a wide range of scientific and technological applications including energy and mass spectroscopy. Neutron depth profiling is a near-surface analysis technique that gives concentration distribution versus depth for certain technologically important light elements. The technique uses thermal or sub-thermal neutrons to initiate (n, p) or (n, alpha) reactions. Concentration versus depth distribution is obtained by the transformation of the energy spectrum into depth distribution by using stopping force tables of the projectiles in the substrate, and by converting the number of counts into concentration using a standard sample of known dose value. Conventionally, neutron depth profiling measurements are based on charged particle spectrometry, which employs semiconductor detectors such as a surface barrier detector (SBD) and the associated electronics. Measurements with semiconductor detectors are affected by a number of broadening mechanisms, which result from the interactions between the projectile ion and the detector material as well as fluctuations in the signal generation process. These are inherent features of the detection mechanism that involve the semiconductor detectors and cannot be avoided. Ion time-of-flight spectrometry offers highly precise measurement capabilities, particularly for slow particles. For high-energy low-mass particles, measurement resolution tends to degrade with all other parameters fixed. The threshold for more precise ion energy measurements with respect to conventional techniques, such as direct energy measurement by a surface barrier detector, is directly related to the design and operating parameters of the device. Time-of-flight spectrometry involves correlated detection of two signals by a coincidence unit. In ion time-of-flight spectroscopy, the ion generates the primary input

  1. Time course-changes in phosphatidylcholine profile during oxidative modification of low-density lipoprotein

    Science.gov (United States)

    2014-01-01

    Background Oxidized phosphatidylcholines (oxPC) and lysophosphatidylcholine (lysoPC) generated during the formation of oxidized low-density lipoprotein (oxLDL) are involved in atherosclerotic lesion development. We investigated the time course-changes in phosphatidylcholine (PC) molecular species during oxidation of LDL to determine how those atherogenic PCs are produced. Methods Human and rabbit LDLs were pretreated with or without a selective platelet-activating factor acetylhydrolase (PAF-AH) inhibitor. LDL was oxidized by incubation with copper sulfate, and PC profiles were analyzed by liquid chromatography-tandem mass spectrometry. Results When human LDL was oxidized, the peak areas for polyunsaturated fatty acid (PUFA)-containing PC species dramatically decreased after a short lag period, concomitantly lysoPC species increased sharply. Although a variety of oxPC species containing oxidized fatty acyl groups or cleaved acyl chains are formed during LDL oxidation, only a few oxPC products accumulated in oxLDL: 1-palmitoyl-2-(9-oxo-nonanoyl) PC and long-chain oxPC with two double bonds. Pretreatment of LDL with the PAF-AH inhibitor greatly reduced lysoPC production while it had no effect on lipid peroxidation reactions and oxPC profiles. Rabbit LDL, which has a different composition of PC molecular species and needs a longer time to reach achieve full oxidation than human LDL, also accumulated lysoPC during oxidation. The increase in lysoPC in rabbit oxLDL was suppressed by pretreatment with the PAF-AH inhibitor. The major oxPC species formed in rabbit oxLDL were almost the same as human oxLDL. Conclusions These results suggest that lysoPC species are the major products and PAF-AH activity is crucial for lysoPC generation during oxidation of LDL. The oxPC species accumulated are limited when LDL is oxidized with copper ion in vitro. PMID:24625108

  2. Dynamic Agricultural Land Unit Profile Database Generation using Landsat Time Series Images

    Science.gov (United States)

    Torres-Rua, A. F.; McKee, M.

    2012-12-01

    government efforts for a given occurrence at the land unit level, and affecting the potential economic trade-off level in the area. In this study a framework is proposed to create and continuously update a land unit profile database using historical Landsat satellite imagery records. An experimental test is implemented for the agricultural lands in Central Utah. This location was selected because of their success in increasing the efficiency of water use and control along the entire irrigation system. A set of crop health metrics from the literature (NDVI, LAI, NDWI) is calculated and evaluated to measure crop response to farm management for its evaluation in time. The resulting land unit profile database is then tested to determine land unit profile groups based on land unit management characteristics. Comparison with essential inputs (water availability and climate conditions) and crop type (outputs) on a year basis is provided.

  3. Outcomes of Laparoscopic Treatment Modalities for Unilateral Non-Palpable Testes

    Directory of Open Access Journals (Sweden)

    Nurullah eHamidi

    2016-03-01

    Full Text Available Purpose: To date, laparoscopy has gradually become the gold standard for treatment of NPT with different success and complication rates. In this study, we aimed to evaluate outcomes of laparoscopic approaches for NPT.Materials and Methods: We reviewed data of 82 consecutive patients who underwent laparoscopic treatment for unilateral NPT at two institutions by two high volume surgeons from 2004 January to 2014 December. Laparoscopic-assisted orchidopexy(LAO and two stage Fowler-Stephens technique(FST was performed for 45 and 37 patients, respectively. Age(at surgery, follow-up time, laterality of testes and post-operative complications were analyzed. Modified Clavien classification system(MCCS was used for evaluating complications.Results: The median age (at surgery and median follow-up time were 18(range: 6-56 and 60(range: 9-130 months, respectively. Overall success rate for two laparoscopy techniques was 87.8 % during the maximal follow-up time. We observed wound infection in 2, hematoma in one, testicular atrophy in 5, testicular re-ascending in 2 patients at follow-up period. There was no statistical difference between two laparoscopic techniques for grade 1(5 vs. 2 patients, p=0.14 and grade IIIb MCCS complications(1 vs. 2 patients, p=0.44.Conclusions: Our results have shown that two laparoscopic approaches have low complication rates.

  4. A real time chemotaxis assay unveils unique migratory profiles amongst different primary murine macrophages.

    Directory of Open Access Journals (Sweden)

    Asif J Iqbal

    Full Text Available Chemotaxis assays are an invaluable tool for studying the biological activity of inflammatory mediators such as CC chemokines, which have been implicated in a wide range of chronic inflammatory diseases. Conventional chemotaxis systems such as the modified Boyden chamber are limited in terms of the data captured given that the assays are analysed at a single time-point. We report the optimisation and validation of a label-free, real-time cell migration assay based on electrical cell impedance to measure chemotaxis of different primary murine macrophage populations in response to a range of CC chemokines and other chemoattractant signalling molecules. We clearly demonstrate key differences in the migratory behavior of different murine macrophage populations and show that this dynamic system measures true macrophage chemotaxis rather than chemokinesis or fugetaxis. We highlight an absolute requirement for Gαi signaling and actin cytoskeletal rearrangement as demonstrated by Pertussis toxin and cytochalasin D inhibition. We also studied the chemotaxis of CD14(+ human monocytes and demonstrate distinct chemotactic profiles amongst different monocyte donors to CCL2. This real-time chemotaxis assay will allow a detailed analysis of factors that regulate macrophage responses to chemoattractant cytokines and inflammatory mediators.

  5. Recursive regularization for inferring gene networks from time-course gene expression profiles

    Directory of Open Access Journals (Sweden)

    Nagasaki Masao

    2009-04-01

    Full Text Available Abstract Background Inferring gene networks from time-course microarray experiments with vector autoregressive (VAR model is the process of identifying functional associations between genes through multivariate time series. This problem can be cast as a variable selection problem in Statistics. One of the promising methods for variable selection is the elastic net proposed by Zou and Hastie (2005. However, VAR modeling with the elastic net succeeds in increasing the number of true positives while it also results in increasing the number of false positives. Results By incorporating relative importance of the VAR coefficients into the elastic net, we propose a new class of regularization, called recursive elastic net, to increase the capability of the elastic net and estimate gene networks based on the VAR model. The recursive elastic net can reduce the number of false positives gradually by updating the importance. Numerical simulations and comparisons demonstrate that the proposed method succeeds in reducing the number of false positives drastically while keeping the high number of true positives in the network inference and achieves two or more times higher true discovery rate (the proportion of true positives among the selected edges than the competing methods even when the number of time points is small. We also compared our method with various reverse-engineering algorithms on experimental data of MCF-7 breast cancer cells stimulated with two ErbB ligands, EGF and HRG. Conclusion The recursive elastic net is a powerful tool for inferring gene networks from time-course gene expression profiles.

  6. Accuracy of combined clinical findings and fine needle aspiration cytology for the diagnosis in palpable breast tumors.

    Science.gov (United States)

    Carrillo, J F; Mendivil, M F; Domínguez, J R; de Obaldía, G E; Esparza, R

    1999-01-01

    A prospective study to evaluate the confidence level and predictive value of the fine needle aspiration biopsy was performed in the Oncology Service, "Hospital 20 de Noviembre, ISSSTE", Mexico City. The cases with a palpable breast tumor, histologically confirmed who presented from 1992 to 1994 were included. One aspirate was done in each patient and these were reviewed by the same pathologist. We determined sensitivity, specificity and predictive value of the test. Age, border characteristics, size and mobility of the tumor were evaluated by Bayesian analysis. From 213 aspirates, 199 were elegible for diagnosis, 98 (46%) had a diagnosis of carcinoma, 13 were acellular and one suggestive. The acellular diagnoses were considered negative and suggestive positive, for analysis purposes. Mean age and tumor size were: 46.6 years (range 14-90) and 3.7 cm. (range 1-13) respectively. Sensitivity (0.932), specificity (0.973) and positive predictive value (96.9%) were estimated. We observed a high probability of true positive [P(D+/T+)] > 0.8 results in patients between 40 and 60 years of age, irregular borders, size > 2 cm and fixed lesions. The test has a high confidence level and in presence of two or more of the clinical factors mentioned, definitive decisions regarding treatment could be taken, without need of histologic confirmation.

  7. Stereotaxic Fine-Needle Aspiration Cytologic Evaluation of Non-palpable Breast Lesions

    Directory of Open Access Journals (Sweden)

    M Haghighi

    2005-07-01

    Full Text Available Background: Although long-term mammography is the standard means of evaluation for the probably benign lesions of breast, some times we feel obliged to know about the benignity and the extent of lesions earlier. Therefore we evaluated the diagnostic value of stereotaxic fine-needle aspiration (SFNA in low suspicion breast lesions as an alternative to the routine modality. Methods: The study included 150 low-suspicion or probably benign breast lesions detected on mammography. All cases underwent SFNA and followed by exciosional biopsy or follow-up mammography based on SFNA findings. Results: Fibroadenoma and normal tissue lesions were diagnosed in 57% of patients, in whom no evidence of malignancy was found in the follow-up period. In 48 patients with cytologic findings suggestive of proliferative fibrocystic disease, three cases of malignancy were detected by excisional biopsy. Conclusion: A SFNA result suggesting benignity allows safe clinical follow-up, whereas a suspicious or equivocal diagnosis needs more invasive modalities for further investigations. Key words: Breast, Mammography, Stereotaxic, Fine-Needle Aspiration (FNA

  8. Real-Time Gene Expression Profiling of Live Shewanella Oneidensis Cells

    Energy Technology Data Exchange (ETDEWEB)

    Xiaoliang Sunney Xie

    2009-03-30

    The overall objective of this proposal is to make real-time observations of gene expression in live Shewanella oneidensis cells with high sensitivity and high throughput. Gene expression, a central process to all life, is stochastic because most genes often exist in one or two copies per cell. Although the central dogma of molecular biology has been proven beyond doubt, due to insufficient sensitivity, stochastic protein production has not been visualized in real time in an individual cell at the single-molecule level. We report the first direct observation of single protein molecules as they are generated, one at a time in a single live E. coli cell, yielding quantitative information about gene expression [Science 2006; 311: 1600-1603]. We demonstrated a general strategy for live-cell single-molecule measurements: detection by localization. It is difficult to detect single fluorescence protein molecules inside cytoplasm - their fluorescence is spread by fast diffusion to the entire cell and overwhelmed by the strong autofluorescence. We achieved single-molecule sensitivity by immobilizing the fluorescence protein on the cell membrane, where the diffusion is much slowed. We learned that under the repressed condition protein molecules are produced in bursts, with each burst originating from a stochastically-transcribed single messenger RNA molecule, and that protein copy numbers in the bursts follow a geometric distribution. We also simultaneously published a paper reporting a different method using β-glactosidase as a reporter [Nature 440, 358 (2006)]. Many important proteins are expressed at low levels, inaccessible by previous proteomic techniques. Both papers allowed quantification of protein expression with unprecedented sensitivity and received overwhelming acclaim from the scientific community. The Nature paper has been identified as one of the most-cited papers in the past year [http://esi-topics.com/]. We have also an analytical framework describing the

  9. Investigation of storage time-dependent alterations of enantioselective amino acid profiles in kimchi using liquid chromatography-time of flight mass spectrometry.

    Science.gov (United States)

    Taniguchi, Moyu; Konya, Yutaka; Nakano, Yosuke; Fukusaki, Eiichiro

    2017-10-01

    Although naturally abundant amino acids are represented mainly by l-enantiomers, fermented foods are known to contain various d-amino acids. Enantiospecific profiles of food products can vary due to fermentation by bacteria, and such alterations may contribute to changes in food properties that would not be dependent exclusively on l-amino acids. Therefore, more attention should be paid to the study of temporal alterations of d-amino acid profiles during fermentation process. However, there have been very few studies reporting time-dependent profiling of d-amino acids because enantioseparation of widely targeted d-amino acids is technically difficult. This study aimed to achieve high throughput profiling of amino acids enantiomers. Enantioselective profiling of amino acids using CROWNPAK CR-I(+) column, liquid chromatography, time of flight mass spectrometry, and principle component analysis was performed to investigate time-dependent alterations in concentrations of free d- and l-amino acids in kimchi stored at 4°C or 25°C. We demonstrated significant changes in d- and l-amino acid profiles in kimchi stored at 25°C. In particular, concentrations of the amino acids d-Ala, d-Ser, d-allo-Ile, d-Leu, d-Asp, d-Glu, and d-Met became higher in kimchi with storage time. This is the first report of time-dependent alterations of d- and l-amino acid contents in kimchi. This study showed that our analytical method of enantioselective detection of amino acids using liquid chromatography time-of-flight mass spectrometry (LC-TOFMS) with CROWNPAK CR-I(+) enables high throughput food screening and can be recommended for advanced studies of the relationship between d-amino acid content and food properties. Copyright © 2017 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

  10. Time course of gene expression profiling in the liver of experimental mice infected with Echinococcus multilocularis.

    Directory of Open Access Journals (Sweden)

    Renyong Lin

    Full Text Available BACKGROUND: Alveolar echinococcosis (AE is a severe chronic parasitic disease which behaves like a slow-growing liver cancer. Clinical observations suggest that the parasite, Echinococcus multilocularis (E. multilocularis influences liver homeostasis and hepatic cell metabolism. However, this has never been analyzed during the time course of infection in the common model of secondary echinococcosis in experimental mice. METHODOLOGY/PRINCIPAL FINDINGS: Gene expression profiles were assessed using DNA microarray analysis, 1, 2, 3 and 6 months after injection of E. multilocularis metacestode in the liver of susceptible mice. Data were collected at different time points to monitor the dynamic behavior of gene expression. 557 differentially expressed genes were identified at one or more time points, including 351 up-regulated and 228 down-regulated genes. Time-course analysis indicated, at the initial stage of E. multilocularis infection (month 1-2, that most of up-regulated pathways were related to immune processes and cell trafficking such as chemokine-, mitogen-activated protein kinase (MAPK signaling, and down-regulated pathways were related to xenobiotic metabolism; at the middle stage (month 3, MAPK signaling pathway was maintained and peroxisome proliferator-activated receptor (PPAR signaling pathway emerged; at the late stage (month 6, most of up-regulated pathways were related to PPAR signaling pathway, complement and coagulation cascades, while down-regulated pathways were related to metabolism of xenobiotics by cytochrome P450. Quantitative RT-PCR analysis of a random selection of 19 genes confirmed the reliability of the microarray data. Immunohistochemistry analysis showed that proliferating cell nuclear antigen (PCNA was increased in the liver of E. multilocularis infected mice from 2 months to 6 months. CONCLUSIONS: E. multilocularis metacestode definitely exerts a deep influence on liver homeostasis, by modifying a number of gene

  11. Versican but not decorin accumulation is related to malignancy in mammographically detected high density and malignant-appearing microcalcifications in non-palpable breast carcinomas

    Directory of Open Access Journals (Sweden)

    Kalofonos Haralabos P

    2011-07-01

    Full Text Available Abstract Background Mammographic density (MD and malignant-appearing microcalcifications (MAMCs represent the earliest mammographic findings of non-palpable breast carcinomas. Matrix proteoglycans versican and decorin are frequently over-expressed in various malignancies and are differently involved in the progression of cancer. In the present study, we have evaluated the expression of versican and decorin in non-palpable breast carcinomas and their association with high risk mammographic findings and tumor characteristics. Methods Three hundred and ten patients with non-palpable suspicious breast lesions, detected during screening mammography, were studied. Histological examination was carried out and the expression of decorin, versican, estrogen receptor α (ERα, progesterone receptor (PR and c-erbB2 (HER-2/neu was assessed by immunohistochemistry. Results Histological examination showed 83 out of 310 (26.8% carcinomas of various subtypes. Immunohistochemistry was carried out in 62/83 carcinomas. Decorin was accumulated in breast tissues with MD and MAMCs independently of the presence of malignancy. In contrast, versican was significantly increased only in carcinomas with MAMCs (median ± SE: 42.0 ± 9.1 and MD (22.5 ± 10.1 as compared to normal breast tissue with MAMCs (14.0 ± 5.8, MD (11.0 ± 4.4 and normal breast tissue without mammographic findings (10.0 ± 2.0. Elevated levels of versican were correlated with higher tumor grade and invasiveness in carcinomas with MD and MAMCs, whereas increased amounts of decorin were associated with in situ carcinomas in MAMCs. Stromal deposition of both proteoglycans was related to higher expression of ERα and PR in tumor cells only in MAMCs. Conclusions The specific accumulation of versican in breast tissue with high MD and MAMCs only in the presence of malignant transformation and its association with the aggressiveness of the tumor suggests its possible use as molecular marker in non-palpable

  12. High intensity profile monitor for time resolved spectrometry at the CLIC Test Facility 3

    Energy Technology Data Exchange (ETDEWEB)

    Olvegard, M., E-mail: maja.olvegard@physics.uu.se [CERN, CH-1211 Geneva 23 (Switzerland); Uppsala University, P.O. Box 256, SE-751 05 (Sweden); Adli, E. [CERN, CH-1211 Geneva 23 (Switzerland); University of Oslo, Boks 1072 Blindern, NO-0316 Oslo (Norway); Braun, H.H. [Paul Scherrer Institut, CH-5232 Villigen PSI (Switzerland); Bravin, E.; Chritin, N.; Corsini, R.; Dabrowski, A.E.; Doebert, S.; Dutriat, C. [CERN, CH-1211 Geneva 23 (Switzerland); Egger, D. [CERN, CH-1211 Geneva 23 (Switzerland); Ecole Polytechnique Federale de Lausanne, CH-1015, Lausanne (Switzerland); Lefevre, T. [CERN, CH-1211 Geneva 23 (Switzerland); Mete, O. [CERN, CH-1211 Geneva 23 (Switzerland); Ecole Polytechnique Federale de Lausanne, CH-1015, Lausanne (Switzerland); Skowronski, P.K.; Tecker, F. [CERN, CH-1211 Geneva 23 (Switzerland)

    2012-08-11

    The power source of the Compact LInear Collider (CLIC) relies on the generation and deceleration of a high-intensity electron drive beam. In order to provide the best radio-frequency (RF) to beam-energy transfer efficiency, the electron beam is accelerated using fully loaded RF cavities, which leads to strong beam loading effects resulting in a high-energy transient. The stability of the RF power produced by the drive beam depends on the stability of the drive beam energy and energy spread along the pulse. The control and the monitoring of the time evolution of the beam energy distribution are therefore crucial for the accelerator performance. For this purpose segmented beam dumps, which are simple and robust devices, have been designed and installed at the CLIC Test Facility 3 (CTF3). These devices are located at the end of spectrometer lines and provide horizontal beam profiles with a time resolution better than 10 ns. The segmented dumps are composed of parallel, vertical, metallic plates, and are based on the same principle as a Faraday cup: the impinging beam current is read by a fast acquisition channel. Both FLUKA and Geant4 simulations were performed to define the optimum detector geometry for beam energies ranging from 5 MeV to 150 MeV. This paper presents a detailed description of the different steps of the design: the optimization of the detector spatial resolution, the minimization of the thermal load and the long-term damage resulting from high radiation doses. Four segmented dumps are currently used in the CTF3 complex. Their measured performance and limitations are presented in this paper. Typical beam spectra as measured in the CTF3 linac are also presented along with a description of the RF manipulations needed for tuning the beam energy spectrum.

  13. REAL-TIME STABILITY AND PROFILE COMPARISON MEASUREMENTS BETWEEN TWO DIFFERENT LTPS.

    Energy Technology Data Exchange (ETDEWEB)

    QIAN, S.; WANG, D.J.

    2005-07-31

    The Long Trace Profiler (LTP) is a precise angle measurement instrument, with a sensitivity and accuracy that can be in the sub-micron radian range. LTP characteristics depend on the particular LTP system schematic design, and the quality of components and assembly. The conditions of temperature, alignment, and mirror support during the measurement process vary between different laboratories, which influences significantly the test repeatability and accuracy. In this paper we introduce a direct comparison method to test the same object at the same point in the same environment at the same time by using two LTPs, which significantly increases the reliability of the comparison. A compact, portable LTP (PTLTP), which can be carried to different laboratories around the world, is used for comparison testing. Stability Comparison experiments between the LTP II at the National Synchrotron Radiation Research Center (NSRRC), and the PTLTP of Brookhaven National Laboratory (BNL) reveal significant differences in performance between the instruments. The experiment is set up so that each optical head simultaneously records both its own sample probe beam and also the probe beam from the other optical head. The two probe beams are reflected from same point on the mirror. Tests show that the stability of the PTLTP with a monolithic beam splitter is 10 times better than the stability of the LTP II which has a separated beam splitter unit. A scheme for comparing scanning measurements of a mirror is introduced. Experimental results show a significant difference between the two LTPs due mainly to distortions in the optical components inside the optical head. A new scheme is proposed for further mirror comparison scanning tests.

  14. Making the Future Palpable

    DEFF Research Database (Denmark)

    Büscher, Monika; Kristensen, Margit; Mogensen, Preben Holst

    2007-01-01

    In this paper we describe experiences from a Future Laboratory. Future laboratories allow users to experiment with prototypes of future technologies in as realistic as possible conditions. We have devised this method because, to realize the potential of advanced ubiquitous computing technologies...

  15. Real-time transcriptional profiling of cellular and viral gene expression during lytic cytomegalovirus infection.

    Directory of Open Access Journals (Sweden)

    Lisa Marcinowski

    2012-09-01

    Full Text Available During viral infections cellular gene expression is subject to rapid alterations induced by both viral and antiviral mechanisms. In this study, we applied metabolic labeling of newly transcribed RNA with 4-thiouridine (4sU-tagging to dissect the real-time kinetics of cellular and viral transcriptional activity during lytic murine cytomegalovirus (MCMV infection. Microarray profiling on newly transcribed RNA obtained at different times during the first six hours of MCMV infection revealed discrete functional clusters of cellular genes regulated with distinct kinetics at surprising temporal resolution. Immediately upon virus entry, a cluster of NF-κB- and interferon-regulated genes was induced. Rapid viral counter-regulation of this coincided with a very transient DNA-damage response, followed by a delayed ER-stress response. Rapid counter-regulation of all three clusters indicated the involvement of novel viral regulators targeting these pathways. In addition, down-regulation of two clusters involved in cell-differentiation (rapid repression and cell-cycle (delayed repression was observed. Promoter analysis revealed all five clusters to be associated with distinct transcription factors, of which NF-κB and c-Myc were validated to precisely match the respective transcriptional changes observed in newly transcribed RNA. 4sU-tagging also allowed us to study the real-time kinetics of viral gene expression in the absence of any interfering virion-associated-RNA. Both qRT-PCR and next-generation sequencing demonstrated a sharp peak of viral gene expression during the first two hours of infection including transcription of immediate-early, early and even well characterized late genes. Interestingly, this was subject to rapid gene silencing by 5-6 hours post infection. Despite the rapid increase in viral DNA load during viral DNA replication, transcriptional activity of some viral genes remained remarkably constant until late-stage infection, or was

  16. Integrated inertial sensors and mobile computing for real-time cycling performance guidance via pedaling profile classification.

    Science.gov (United States)

    Xu, James Y; Nan, Xiaomeng; Ebken, Victor; Wang, Yan; Pottie, Greg J; Kaiser, William J

    2015-03-01

    Today, the bicycle is utilized as a daily commute tool, a physical rehabilitation asset, and sporting equipment, prompting studies into the biomechanics of cycling. Of the number of important parameters that affect cycling efficiency, the foot angle profile is one of the most important as it correlates directly with the effective force applied to the bike. However, there has been no compact and portable solution for measuring the foot angle and for providing the cyclist with real-time feedback due to a number of difficulties of the current tracking and sensing technologies and the myriad types of bikes available. This paper presents a novel sensing and mobile computing system for classifying the foot angle profiles during cycling and for providing real-time guidance to the user to achieve the correct profile. Continuous foot angle tracking is firstly converted into a discrete problem requiring only recognition of acceleration profiles of the foot using a single shoe mounted tri-axial accelerometer during each pedaling cycle. A classification method is then applied to identify the pedaling profile. Finally, a mobile solution is presented to provide real-time signal processing and guidance.

  17. Integrated pathway modules using time-course metabolic profiles and EST data from Milnesium tardigradum

    Directory of Open Access Journals (Sweden)

    Beisser Daniela

    2012-06-01

    Full Text Available Abstract Background Tardigrades are multicellular organisms, resistant to extreme environmental changes such as heat, drought, radiation and freezing. They outlast these conditions in an inactive form (tun to escape damage to cellular structures and cell death. Tardigrades are apparently able to prevent or repair such damage and are therefore a crucial model organism for stress tolerance. Cultures of the tardigrade Milnesium tardigradum were dehydrated by removing the surrounding water to induce tun formation. During this process and the subsequent rehydration, metabolites were measured in a time series by GC-MS. Additionally expressed sequence tags are available, especially libraries generated from the active and inactive state. The aim of this integrated analysis is to trace changes in tardigrade metabolism and identify pathways responsible for their extreme resistance against physical stress. Results In this study we propose a novel integrative approach for the analysis of metabolic networks to identify modules of joint shifts on the transcriptomic and metabolic levels. We derive a tardigrade-specific metabolic network represented as an undirected graph with 3,658 nodes (metabolites and 4,378 edges (reactions. Time course metabolite profiles are used to score the network nodes showing a significant change over time. The edges are scored according to information on enzymes from the EST data. Using this combined information, we identify a key subnetwork (functional module of concerted changes in metabolic pathways, specific for de- and rehydration. The module is enriched in reactions showing significant changes in metabolite levels and enzyme abundance during the transition. It resembles the cessation of a measurable metabolism (e.g. glycolysis and amino acid anabolism during the tun formation, the production of storage metabolites and bioprotectants, such as DNA stabilizers, and the generation of amino acids and cellular components from

  18. Value and efficiency of sentinel lymph node diagnostics in patients with penile carcinoma with palpable inguinal lymph nodes as a new multimodal, minimally invasive approach

    Energy Technology Data Exchange (ETDEWEB)

    Luetzen, Ulf; Zuhayra, Maaz; Marx, Marlies; Zhao, Yi [University Hospital Schleswig Holstein, Campus Kiel, Department of Nuclear Medicine, Molecular Imaging Diagnostics and Therapy, Kiel (Germany); Colberg, Christian; Knuepfer, Stephanie; Juenemann, Klaus-Peter; Naumann, Carsten Maik [University Hospital Schleswig Holstein, Campus Kiel, Department of Urology and Pediatric Urology, Kiel (Germany); Baumann, Rene [University Hospital Schleswig Holstein, Campus Kiel, Department of Radio Oncology, Kiel (Germany); Kaehler, Katharina Charlotte [University Hospital Schleswig Holstein, Campus Kiel, Department of Dermatology, Venerology and Allergology, Kiel (Germany)

    2016-12-15

    The international guidelines recommend sentinel lymph node biopsy (SLNB) for lymph node staging in penile cancer with non-palpable inguinal lymph nodes (LN) but it is not recommended with palpable inguinal LN. The aim of this study was to evaluate the reliability and morbidity of SLNB in combination with an ultrasound-guided resection of suspect inguinal LNs as a new multimodal, minimally invasive staging approach in these patients. We performed SLNB in 26 penile cancer patients with 42 palpable inguinal LNs. Prior to the combined staging procedures the patients underwent an ultrasound examination of the groins as well as planar lymphatic drainage scintigraphy and SPECT/CT scans. During the surgical procedure, the radioactive-labelled sentinel lymph nodes and, in addition, sonographically suspect LNs, were resected under ultrasound guidance. Follow-up screening was done by ultrasound examination of the groins according to the guidelines of the European Association of Urology. Nineteen groins of 42 preoperatively palpable inguinal findings were histologically tumor-positive. SLNB alone showed lymphogenic metastases in 14 groins. Sonography revealed five further metastatic groins, which would not have been detected during SLNB due to a tumor-related blockage of lymphatic drainage or a so-called re-routing of the tracer. During follow-up, none of the 28 groins with tumor-negative LN status showed any LN recurrence in this combined investigation technique. The median follow-up period was 46 (24 to 92) months. Morbidity of this procedure was low at 4.76 % in relation to the number of groins resp. 7.69 % in relation to the number of patients. The results show that this combined procedure is a reliable multimodal diagnostic approach for treatment of penile cancer patients with palpable inguinal LNs. It is associated with low morbidity rates. SLNB alone would lead to a significantly higher false-negative rate in these patients. The encouraging results of this work can

  19. A Study on Real-Time Pricing Method of Reactive Power in Voltage Profile Control Method of Future Distribution Network

    Science.gov (United States)

    Koide, Akira; Tsuji, Takao; Oyama, Tsutomu; Hashiguchi, Takuhei; Goda, Tadahiro; Shinji, Takao; Tsujita, Shinsuke

    It is of prime importance to solve the voltage maintenance problem caused by the introduction of a large number of distributed generators. The authors have proposed “voltage profile control method” using reactive power control of distributed generators and developed new systems which can give economical incentives to DG owners who cooperate the voltage profile management in the previous works. However, it is difficult to apply the proposed economical systems to real-time operation because they are based on the optimization technology and the specific amount of incentive is informed after the control action has finished. Therefore, in this paper, we develop a new method that can determine the amount of incentives in real-time and encourage the costumers to cooperate voltage profile control method. The proposed method is tested in one feeder distribution network and its effectiveness is shown.

  20. Time course effects of fermentation on fatty acid and volatile compound profiles of Cheonggukjang using new soybean cultivars.

    Science.gov (United States)

    Cho, Kye Man; Lim, Ho-Jeong; Kim, Mi-So; Kim, Da Som; Hwang, Chung Eun; Nam, Sang Hae; Joo, Ok Soo; Lee, Byong Won; Kim, Jae Kyeom; Shin, Eui-Cheol

    2017-07-01

    In this study, we investigated the effects of the potential probiotic Bacillus subtilis CSY191 on the fatty acid profiles of Cheonggukjang, a fermented soybean paste, prepared using new Korean brown soybean cultivars, protein-rich cultivar (Saedanbaek), and oil-rich cultivar (Neulchan). Twelve fatty acids were identified in the sample set-myristic, palmitic, palmitoleic, stearic, oleic, vaccenic, linoleic, α-linolenic, arachidic, gondoic, behenic, and lignoceric acids-yet, no specific changes driven by fermentation were noted in the fatty acid profiles. To further explore the effects of fermentation of B. subtilis CSY191, complete profiles of volatiles were monitored. In total, 121, 136, and 127 volatile compounds were detected in the Saedanbaek, Daewon (control cultivar), and Neulchan samples, respectively. Interestingly, the content of pyrazines-compounds responsible for pungent and unpleasant Cheonggukjang flavors-was significantly higher in Neulchan compared to that in Saedanbaek. Although the fermentation period was not a strong factor affecting the observed changes in fatty acid profiles, we noted that profiles of volatiles in Cheonggukjang changed significantly over time, and different cultivars represented specific volatile profiles. Thus, further sensory evaluation might be needed to determine if such differences influence consumers' preferences. Furthermore, additional studies to elucidate the associations between B. subtilis CSY191 fermentation and other nutritional components (e.g., amino acids) and their health-promoting potential are warranted. Copyright © 2016. Published by Elsevier B.V.

  1. Effects of time-temperature profiles on glow curves of germanium-doped optical fibre

    Science.gov (United States)

    Lam, S. E.; Alawiah, A.; Bradley, D. A.; Mohd Noor, N.

    2017-08-01

    The Germanium (Ge) doped silica optical fibres have demonstrated the great potential to be developed as a thermoluminescent (TL) dosimeter that can be used in various applications in radiotherapy, diagnostic radiology, UV dosimetry system and food irradiation industry. Different time-temperature profile (TTP) parameters of the TL reader have been employed by many researchers in various of TL studies. Nevertheless, none of those studies adequately addressed the effects of the reader's preheat temperature and heating rate on the kinetic parameters of the TL glow curve specifically, the Ge-doped silica optical fibres. This research addresses the issue of TTP parameters with special attention to the determination of the kinetic parameters of the glow curve. The glow curve responses were explored and the kinetic parameters were analyzed by the WinGCF software, to show the effect of the preheat temperature and heating rate of the reader on Ge-doped fibre irradiated with 18 Gy of 6 MV photons radiation. The effect of TTP parameters was discussed and compared against the commercial fibre and tailored made fibre of 6 mol% Ge-doped of flat and cylindrical shape. The deconvolution of glow peaks and the kinetic parameters were obtained by the WinGCF software. This enables to fit accurately (1.5%

  2. Depth Profile Analysis of Amorphous Silicon Thin Film Solar Cells by Pulsed Radiofrequency Glow Discharge Time of Flight Mass Spectrometry

    Science.gov (United States)

    Alvarez-Toral, Aitor; Sanchez, Pascal; Menéndez, Armando; Pereiro, Rosario; Sanz-Medel, Alfredo; Fernández, Beatriz

    2015-02-01

    Among the different solar cell technologies, amorphous silicon (a-Si:H) thin film solar cells (TFSCs) are today very promising and, so, TFSCs analytical characterization for quality control issues is increasingly demanding. In this line, depth profile analysis of a-Si:H TFSCs on steel substrate has been investigated by using pulsed radiofrequency glow discharge-time of flight mass spectrometry (rf-PGD-TOFMS). First, to discriminate potential polyatomic interferences for several analytes (e.g., 28Si+, 31P+, and 16O+) appropriate time positions along the GD pulse profile were selected. A multi-matrix calibration approach, using homogeneous certified reference materials without hydrogen as well as coated laboratory-made standards containing hydrogen, was employed for the methodological calibration. Different calibration strategies (in terms of time interval selection on the pulse profile within the afterglow region) have been compared, searching for optimal calibration graphs correlation. Results showed that reliable and fast quantitative depth profile analysis of a-Si:H TFSCs by rf-PGD-TOFMS can be achieved.

  3. Innovative real-time and non-destructive method of beam profile measurement under large beam current irradiation for BNCT

    Science.gov (United States)

    Takada, M.; Kamada, S.; Suda, M.; Fujii, R.; Nakamura, M.; Hoshi, M.; Sato, H.; Endo, S.; Hamano, T.; Arai, S.; Higashimata, A.

    2012-10-01

    We developed a real-time and non-destructive method of beam profile measurement on a target under large beam current irradiation, and without any complex radiation detectors or electrical circuits. We measured the beam profiles on a target by observing the target temperature using an infrared-radiation thermometer camera. The target temperatures were increased and decreased quickly by starting and stopping the beam irradiation within 1 s in response speed. Our method could trace beam movements rapidly. The beam size and position were calibrated by measuring O-ring heat on the target. Our method has the potential to measure beam profiles at beam current over 1 mA for proton and deuteron with the energy around 3 MeV and allows accelerator operators to adjust the beam location during beam irradiation experiments without decreasing the beam current.

  4. Innovative real-time and non-destructive method of beam profile measurement under large beam current irradiation for BNCT

    Energy Technology Data Exchange (ETDEWEB)

    Takada, M., E-mail: m_takada@nirs.go.jp [National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba 263-8555 (Japan); Kamada, S.; Suda, M. [National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba 263-8555 (Japan); Fujii, R.; Nakamura, M. [Cancer Intelligence Care Systems, Inc., 3-5-7 Ariake, Koto-ku, Tokyo 135-0063 (Japan); Hoshi, M. [Research Institute for Radiation Biology and Medicine, Hiroshima University, 1-2-3 kasumi, Minami-ku, Hiroshima 734-8553 (Japan); Sato, H. [Ibaraki Prefectural University of Health Sciences, 4669-2, Ami Ami-Cho, Inashiki-gun, Ibaraki 300-0394 (Japan); Endo, S. [Quantum Energy Applications, Graduate School of Engineering, Hiroshima University, 1-4-1 Kagamiyama, Higashi-Hiroshima 739-8527 (Japan); Hamano, T. [National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba 263-8555 (Japan); Arai, S.; Higashimata, A. [Sanki Industry Co., 318-6, Sannoh, Inage-ku, Chiba 263-0002 (Japan)

    2012-10-11

    We developed a real-time and non-destructive method of beam profile measurement on a target under large beam current irradiation, and without any complex radiation detectors or electrical circuits. We measured the beam profiles on a target by observing the target temperature using an infrared-radiation thermometer camera. The target temperatures were increased and decreased quickly by starting and stopping the beam irradiation within 1 s in response speed. Our method could trace beam movements rapidly. The beam size and position were calibrated by measuring O-ring heat on the target. Our method has the potential to measure beam profiles at beam current over 1 mA for proton and deuteron with the energy around 3 MeV and allows accelerator operators to adjust the beam location during beam irradiation experiments without decreasing the beam current.

  5. Doctoral Students’ Social Support Profiles and Their Relationship to Burnout, Drop-Out Intentions, and Time to Candidacy

    Directory of Open Access Journals (Sweden)

    Jouni A Peltonen

    2017-08-01

    Full Text Available Aim/Purpose: The primary aim of this study was to better understand the individual variations in supervisory and researcher community support among doctoral students by analyzing the social support profiles of Finnish doctoral students. The differences among the profiles, in terms of satisfaction with supervision, experienced burnout, time to candidacy and disciplinary background were also examined. Background: This study explores social support profiles and their association with the experienced burnout, satisfaction with supervision, drop-out intentions, disciplinary background, and form of dissertation among doctoral students by employing a person-oriented approach. Methodology: In total, 402 doctoral students from a Finnish university completed a Doctoral Experience survey. Latent Profile Analysis (LPA was used to group doctoral students according to social support from supervisors and the researcher community. Contribution: The present study is among the first quantitative studies to explore doctoral student social support profiles and their association with burnout, drop-out intentions, and time to candidacy. It brings into focus the importance of supervisory and researcher community support as one of the most crucial assets of doctoral education in researcher communities. Findings: Two social support profiles, a sufficient support from supervisor and researched community, and b insufficient support from both of these, were identified. Further investigation suggested that the doctoral students who received sufficient support were less likely to suffer from burnout and were less likely to develop drop-out intentions than students who received insufficient support from their supervisor and the researcher community. Recommendations for Practitioners: A recommendation deriving from this research is to identify students at risk as early as possible and assist them with sufficient support.

  6. Load and weather profile, and time simulation impacts for the PEPITE PV/H{sub 2} project

    Energy Technology Data Exchange (ETDEWEB)

    Darras, C.; Thibault, C.; Muselli, M.; Poggi, P. [University of Corsica, UMR CNRS SPE 6134, Route des Sanguinaires, F-20000 Ajaccio (France); Melscoet, S.; Hoguet, J.C. [HELION Hydrogen Power, Domaine du Petit Arbois - Batiment Jules Verne, BP 71, 13545 Aix en Provence (France); Pinton, E. [Commissariat a l' Energie Atomique (CEA/LITEN), 17 rue des Martyrs, 38 054 Grenoble Cedex 9 (France); Gailly, F.; Turpin, C. [Universite de Toulouse, INP, UPS, LAPLACE (Laboratoire Plasma et Conversion d' Energie), ENSEEIHT, 2 rue Charles Camichel, BP 7122, F-31071 Toulouse cedex 7 (France)

    2010-10-15

    This paper concerns the impacts of the meteorological data, the choice of the load profile, and the time simulation (1-11 years) on the energy flows and on the H{sub 2}/O{sub 2}/H{sub 2}O storage sizing in a photovoltaic/fuel cell/electrolyzer hybrid system (PEPITE project). The simulations were computed with the ORIENTE software. 4 load profiles have been investigated (3 diurnal and one nocturnal) with an identical daily consumption (26 kWh). According to load profiles, the gap observed between the most favorable and the most disadvantageous years induces H{sub 2} storage variations rates between 45.5% and 55.3%. Furthermore, if we compare the most penalizing meteorological year with the sizing when we simulate several successive years, we also obtain variation rates (ration between the standard deviation and the corresponding averaged value) ranges from 24.4 to 37.9% for the 3 diurnal profiles. The nocturnal profile presents specific results because it is unsustainable. The main conclusion of this work is the great importance to consider several consecutive years of tilted irradiation data, 7 in our case, to size the H{sub 2}/O{sub 2}/H{sub 2}O storages. (author)

  7. Molecular profiles as predictive marker for the effect of overall treatment time of radiotherapy in supraglottic larynx squamous cell carcinomas

    DEFF Research Database (Denmark)

    Eriksen, Jesper Grau; Buffa, F.M.; Alsner, Jan

    2004-01-01

    BACKGROUND AND PURPOSE: Reduction of the overall treatment time of radiotherapy increases the probability of local tumour control, but it does not benefit all patients. Identification of molecular marker profiles may aid in the selection of patients likely to benefit from accelerated radiotherapy....... PATIENTS AND METHODS: Two hundred and nine patients with SCC of the supraglottic larynx received primary radiotherapy in the randomised DAHANCA trials to 66-68 Gy, 2 Gy/fx but with different overall treatment times of 9.5 week, 6.5 week and 5.5 week. Formalin-fixed paraffin embedded tumour slides were...... as the endpoint. CONCLUSIONS: Molecular marker profiling may aid in the selection of patients that will benefit of a reduction in overall treatment time of radiotherapy in SCC of the supraglottic larynx....

  8. Predictive Validity of Career Decision-Making Profiles over Time among Chinese College Students

    Science.gov (United States)

    Tian, Lin; Guan, Yanjun; Chen, Sylvia Xiaohua; Levin, Nimrod; Cai, Zijun; Chen, Pei; Zhu, Chengfeng; Fu, Ruchunyi; Wang, Yang; Zhang, Shu

    2014-01-01

    Two studies were conducted to validate the Chinese version of the Career Decision-Making Profiles (CDMP) questionnaire, a multidimensional measure of the way individuals make career decisions. Results of Study 1 showed that after dropping 1 item from the original CDMP scale, the 11-factor structure was supported among Chinese college students (N =…

  9. Scintigraphic study of palpable breast nodes with {sup 99m} Tc-tetrofosmin; Estudo cintilografico de nodulos palpaveis da mama com {sup 99m} Tc - tetrofosmin

    Energy Technology Data Exchange (ETDEWEB)

    Pellini, Marcos Pinto; Fonseca, Lea Mirian Barbosa da [Universidade Federal, Rio de Janeiro, RJ (Brazil). Faculdade de Medicina. Dept. de Radiologia; Amarante Junior, Jose Luiz de Medeiros [Hospital Naval Marcilio Dias, Rio de Janeiro, RJ (Brazil). Servico de Medicina Nuclear; Fabricio, Maria Ines Menescal [Universidade Federal, Rio de Janeiro, RJ (Brazil). Inst. de Ginecologia

    1998-12-01

    In Brazil, breast carcinoma has the greater incidence among women. In 1996, about 31,210 new cases were diagnosed. The purpose of this study is to determine if {sup 99m} technetium-tetrofosmin preferentially concentrates within malignant palpable breast nodes, distinguishing them from the benign lumps. Fifth-four consecutive and unsolicited women, mean age 47.5 +- 10.7 years, with palpable nodes in breast, underwent breast scintigraphy with {sup 99m} technetium-tetrofosmin and excisional biopsy or fine needle puncture within interval eight weeks. Histopathologic studies demonstrated 13 cysts, 1 cyst with local inflammation, 11 fibroadenoma, 2 fibrodysplasias, 3 fibroadenomas with high cellularity, 1 fibrocystic change with local inflammation, 23 invasive intraductal carcinomas and 1 invasive lobular carcinoma. The nodes ranged from 10 to 100 mm in greater diameter. The scintigraphic study yielded 30 true-negative cases, 24 true-positives, no false-negative and 1 false-positive. This case was a fibrocystic lump with local inflammation. Two patients had metastases in axillary lymph nodes, well detected in scintigraphy. The statistic analysis showed: sensitivity, 100%; specificity, 96.8%; accuracy, 98.2%; negative predictive value, 100%; positive predictive value, 96.0%. Nonparametric tests of Fisher and Chi-square rejected the antithesis at a confidence interval of 99.9% (p < 0.001). We concluded that {sup 99m} technetium-tetrofosmin preferentially concentrates in malignant palpable breast nodes and can help to distinguish them from the benign tumors with with very high accuracy. (author)

  10. Ultrasound-guided excision combined with intraoperative assessment of gross macroscopic margins decreases the rate of reoperations for non-palpable invasive breast cancer.

    Science.gov (United States)

    Ramos, Manuel; Díaz, Juan Carlos; Ramos, Teresa; Ruano, Ricardo; Aparicio, Martín; Sancho, Magdalena; González-Orús, José María

    2013-08-01

    The standard technique for intraoperative tumour localization of clinically occult tumours is wire-guided localization (WGL). This, however, this has several disadvantages. The aim of the present work is to report our single-centre experience with intraoperative ultrasound-guided (IOUS) excision, performed by surgeons, combined with intraoperative assessment of macroscopic pathologic and ultrasound margins in non-palpable invasive cancers indicated for conservative breast therapy. Two-hundred and twenty-five non-palpable invasive breast cancers were subjected to excision with IOUS. The lesion was located in the operating room with a high-frequency ultrasound probe (8-12 MHz), which was then used to guide surgical removal. The specimen margins were estimated by ultrasonography and macroscopic pathologic examination. The sensitivity of IOUS and effectiveness in the characterization of the specimen margins were evaluated, assessing the need for reoperation. Pathologic tumour size was 12.0 ± 6.7 mm and 13 lesions (6.4 %) were margins in the 4% of cases (9/225). In 5 cases remains of in situ or invasive carcinoma were found. In two cases, conservative surgery was converted to mastectomy. IOUS excision combined with the intraoperative assessment of the macroscopic margins of non-palpable breast cancers is a safe, useful, and efficient technique. We obtained an excellent characterization of tumour margins with moderate removal of breast tissue and consequently a lower number of reoperations were required and good cosmetic results were obtained. We believe that use of this technique in conservative breast cancer surgery should be recommended. Copyright © 2012 Elsevier Ltd. All rights reserved.

  11. Toxoplasmosis presenting as a swelling in the axillary tail of the breast and a palpable axillary lymph node mimicking malignancy: a case report

    OpenAIRE

    Kamel Dia; Teare Louise; Siriwardana HP Priyantha; Inwang E Reggie

    2011-01-01

    Abstract Introduction Lymphadenopathy is a common finding in toxoplasmosis. A breast mass due to toxoplasmosis is very rare, and only a few cases have been reported. We present a case of toxoplasmosis that presented as a swelling in the axillary tail of the breast with a palpable axillary lymph node which mimicked breast cancer. Case presentation A 45-year-old otherwise healthy Caucasian woman presented with a lump on the lateral aspect of her left breast. Her mother had breast cancer that wa...

  12. Electrical burns in times of economic crisis: A new epidemiologic profile.

    Science.gov (United States)

    Aguilera-Sáez, J; Binimelis, M M; Collado, J M; Dos Santos, B P; García, V; Ruiz-Castilla, M; Serracanta, J; Barret, J P

    2016-12-01

    Electrical injuries and especially those of high voltage still remain a source of high morbidity. Over the past few years, a change in the epidemiologic profile of these lesions was noticed at the Vall d'Hebron University Hospital Burn Unit, corresponding to an increase in cases out of the legal framework. It is our aim to describe this particular subset, to determine the extent of their injuries and to understand the reason for their increased incidence. We think this was favoured by the rise in the unemployment rate, along with higher copper prices. Copyright © 2016 Elsevier Ltd and ISBI. All rights reserved.

  13. Exploring the Time Evolution of Luminosity and Pulse Profile in X-Ray Pulsars.

    Science.gov (United States)

    Laycock, Silas; Christodoulou, Dimitris; Cappallo, Rigel; Ho, Wynn; Coe, Malcolm; Corbet, Robin; Klus, Helen; Kazanas, Demosthenes; Galache, Jose Luis; Fingerman, Samuel; Yang, Jun; Norton, Scott

    2015-01-01

    We report progress in our effort to analyze and model the large collection of observations made by RXTE, XMM-Newton and Chandra of X-ray Binary Pulsars in the Magellanic Clouds. There are >2000 individual RXTE PCA, and > 200 XMM-Newton and Chandra observations of the Magellanic clouds. Each observation covers a large fraction of the whole SMC (or LMC) population, and we are able to deconvolve the often simultaneous signals to create a 20 year record of individual pulsar's activity. Together, these datasets cover the entire range of variability timescales and accretion regimes in High Mass X-ray Binaries. We are compiling a library of energy-resolved pulse profiles covering the entire luminosity and spin-period parameter space. In parallel we are developing a suite of computational models to parameterize the pulse profile morphology. We begin with a pair of isotropically emitting poles with general relativity, and then add complexity in the form of fan and pencil beam components. The initial goal is to discover the ratio of the beam components as a function of accretion rate and luminosity, and ultimately the distribution of offsets between magnetic and spin axes. These products are needed for the next generation of advances in neutron star theory and modeling. This unique dataset enables us to determine the upper and lower limits of accretion powered luminosity in a large statistically complete sample of neutron stars, and hence make several direct tests of fundamental NS parameters and accretion physics.

  14. Systematic evaluation of three microRNA profiling platforms: microarray, beads array, and quantitative real-time PCR array.

    Directory of Open Access Journals (Sweden)

    Bin Wang

    Full Text Available BACKGROUND: A number of gene-profiling methodologies have been applied to microRNA research. The diversity of the platforms and analytical methods makes the comparison and integration of cross-platform microRNA profiling data challenging. In this study, we systematically analyze three representative microRNA profiling platforms: Locked Nucleic Acid (LNA microarray, beads array, and TaqMan quantitative real-time PCR Low Density Array (TLDA. METHODOLOGY/PRINCIPAL FINDINGS: The microRNA profiles of 40 human osteosarcoma xenograft samples were generated by LNA array, beads array, and TLDA. Results show that each of the three platforms perform similarly regarding intra-platform reproducibility or reproducibility of data within one platform while LNA array and TLDA had the best inter-platform reproducibility or reproducibility of data across platforms. The endogenous controls/probes contained in each platform have been observed for their stability under different treatments/environments; those included in TLDA have the best performance with minimal coefficients of variation. Importantly, we identify that the proper selection of normalization methods is critical for improving the inter-platform reproducibility, which is evidenced by the application of two non-linear normalization methods (loess and quantile that substantially elevated the sensitivity and specificity of the statistical data assessment. CONCLUSIONS: Each platform is relatively stable in terms of its own microRNA profiling intra-reproducibility; however, the inter-platform reproducibility among different platforms is low. More microRNA specific normalization methods are in demand for cross-platform microRNA microarray data integration and comparison, which will improve the reproducibility and consistency between platforms.

  15. Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.

    Science.gov (United States)

    Tang, Weihong; Schwienbacher, Christine; Lopez, Lorna M; Ben-Shlomo, Yoav; Oudot-Mellakh, Tiphaine; Johnson, Andrew D; Samani, Nilesh J; Basu, Saonli; Gögele, Martin; Davies, Gail; Lowe, Gordon D O; Tregouet, David-Alexandre; Tan, Adrian; Pankow, James S; Tenesa, Albert; Levy, Daniel; Volpato, Claudia B; Rumley, Ann; Gow, Alan J; Minelli, Cosetta; Yarnell, John W G; Porteous, David J; Starr, John M; Gallacher, John; Boerwinkle, Eric; Visscher, Peter M; Pramstaller, Peter P; Cushman, Mary; Emilsson, Valur; Plump, Andrew S; Matijevic, Nena; Morange, Pierre-Emmanuel; Deary, Ian J; Hicks, Andrew A; Folsom, Aaron R

    2012-07-13

    Activated partial thromboplastin time (aPTT) and prothrombin time (PT) are clinical tests commonly used to screen for coagulation-factor deficiencies. One genome-wide association study (GWAS) has been reported previously for aPTT, but no GWAS has been reported for PT. We conducted a GWAS and meta-analysis to identify genetic loci for aPTT and PT. The GWAS for aPTT was conducted in 9,240 individuals of European ancestry from the Atherosclerosis Risk in Communities (ARIC) study, and the GWAS for PT was conducted in 2,583 participants from the Genetic Study of Three Population Microisolates in South Tyrol (MICROS) and the Lothian Birth Cohorts (LBC) of 1921 and 1936. Replication was assessed in 1,041 to 3,467 individuals. For aPTT, previously reported associations with KNG1, HRG, F11, F12, and ABO were confirmed. A second independent association in ABO was identified and replicated (rs8176704, p = 4.26 × 10(-24)). Pooling the ARIC and replication data yielded two additional loci in F5 (rs6028, p = 3.22 × 10(-9)) and AGBL1 (rs2469184, p = 3.61 × 10(-8)). For PT, significant associations were identified and confirmed in F7 (rs561241, p = 3.71 × 10(-56)) and PROCR/EDEM2 (rs2295888, p = 5.25 × 10(-13)). Assessment of existing gene expression and coronary artery disease (CAD) databases identified associations of five of the GWAS loci with altered gene expression and two with CAD. In summary, eight genetic loci that account for ∼29% of the variance in aPTT and two loci that account for ∼14% of the variance in PT were detected and supported by functional data. Copyright © 2012 The American Society of Human Genetics. Published by Elsevier Inc. All rights reserved.

  16. Analyzing the gene expression profile of anaplastic histology Wilms' tumor with real-time polymerase chain reaction arrays.

    Science.gov (United States)

    Lu, Jun; Tao, Yan-Fang; Li, Zhi-Heng; Cao, Lan; Hu, Shao-Yan; Wang, Na-Na; Du, Xiao-Juan; Sun, Li-Chao; Zhao, Wen-Li; Xiao, Pei-Fang; Fang, Fang; Xu, Li-Xiao; Li, Yan-Hong; Li, Gang; Zhao, He; Ni, Jian; Wang, Jian; Feng, Xing; Pan, Jian

    2015-01-01

    Wilms' tumor (WT) is one of the most common malignant neoplasms of the urinary tract in children. Anaplastic histology (unfavorable histology) accounts for about 10% of whole WTs, and it is the single most important histologic predictor of treatment response and survival in patients with WT; however, until now the molecular basis of this phenotype is not very clearly. A real-time polymerase chain reaction (PCR) array was designed and tested. Next, the gene expression profile of pediatric anaplastic histology WT and normal adjacent tissues were analyzed. These expression data were anlyzed with Multi Experiment View (MEV) cluster software further. Datasets representing genes with altered expression profiles derived from cluster analyses were imported into the Ingenuity Pathway Analysis Tool (IPA). 88 real-time PCR primer pairs for quantitative gene expression analysis of key genes involved in pediatric anaplastic histology WT were designed and tested. The gene expression profile of pediatric anaplastic histology WT is significantly different from adjacent normal controls; we identified 15 genes that are up-regulated and 16 genes that are down-regulated in the former. To investigate biological interactions of these differently regulated genes, datasets representing genes with altered expression profiles were imported into the IPA for further analysis, which revealed three significant networks: Cancer, Hematological Disease, and Gene Expression, which included 27 focus molecules and a significance score of 43. The IPA analysis also grouped the differentially expressed genes into biological mechanisms related to Cell Death and Survival 1.15E(-12), Cellular Development 2.84E(-11), Cellular Growth and Proliferation 2.84E(-11), Gene Expression 4.43E(-10), and DNA Replication, Recombination, and Repair 1.39E(-07). The important upstream regulators of pediatric anaplastic histology WT were TP53 and TGFβ1 signaling (P = 1.15E(-14) and 3.79E(-13), respectively). Our study

  17. Time-course investigation of the gene expression profile during Fasciola hepatica infection: A microarray-based study

    Directory of Open Access Journals (Sweden)

    Jose Rojas-Caraballo

    2015-12-01

    Full Text Available Fasciolosis is listed as one of the most important neglected tropical diseases according with the World Health Organization and is also considered as a reemerging disease in the human beings. Despite there are several studies describing the immune response induced by Fasciola hepatica in the mammalian host, investigations aimed at identifying the expression profile of genes involved in inducing hepatic injury are currently scarce. Data presented here belong to a time-course investigation of the gene expression profile in the liver of BALB/c mice infected with F. hepatica metacercariae at 7 and 21 days after experimental infection. The data published here have been deposited in NCBI's Gene Expression Omnibus and are accessible through GEO Series accession number GSE69588, previously published by Rojas-Caraballo et al. (2015 in PLoS One [1].

  18. Real-time monitoring and chemical profiling of a cultivation process

    DEFF Research Database (Denmark)

    Mortensen, Peter P.; Bro, Rasmus

    2006-01-01

    A method for at-line quality assessment of a cultivation process is developed in order to (1) enable improved process control, (2) enable faster detection of batch end point, and (3) enable immediate quality assessment of final product. Fluorescence excitation-emission measurements are used because...... for predicting product quality (enzymatic activity). The fluorescence data are also modeled by a PARAFAC model, providing a chemically interpretable visualization of the process variation thereby enhancing the possibilities for gaining in-depth process understanding. The results of our investigations...... are that enzyme activity can be predicted directly from fluorescence measurements with an uncertainty comparable to the uncertainty of the chemical reference analysis for the enzyme activity. Chemical profiling of the cultivation process using PARAFAC verifies basic understanding of the cultivation process...

  19. Information criterion-based clustering with order-restricted candidate profiles in short time-course microarray experiments

    Directory of Open Access Journals (Sweden)

    Zhang Baoxue

    2009-05-01

    Full Text Available Abstract Background Time-course microarray experiments produce vector gene expression profiles across a series of time points. Clustering genes based on these profiles is important in discovering functional related and co-regulated genes. Early developed clustering algorithms do not take advantage of the ordering in a time-course study, explicit use of which should allow more sensitive detection of genes that display a consistent pattern over time. Peddada et al. 1 proposed a clustering algorithm that can incorporate the temporal ordering using order-restricted statistical inference. This algorithm is, however, very time-consuming and hence inapplicable to most microarray experiments that contain a large number of genes. Its computational burden also imposes difficulty to assess the clustering reliability, which is a very important measure when clustering noisy microarray data. Results We propose a computationally efficient information criterion-based clustering algorithm, called ORICC, that also takes account of the ordering in time-course microarray experiments by embedding the order-restricted inference into a model selection framework. Genes are assigned to the profile which they best match determined by a newly proposed information criterion for order-restricted inference. In addition, we also developed a bootstrap procedure to assess ORICC's clustering reliability for every gene. Simulation studies show that the ORICC method is robust, always gives better clustering accuracy than Peddada's method and saves hundreds of times computational time. Under some scenarios, its accuracy is also better than some other existing clustering methods for short time-course microarray data, such as STEM 2 and Wang et al. 3. It is also computationally much faster than Wang et al. 3. Conclusion Our ORICC algorithm, which takes advantage of the temporal ordering in time-course microarray experiments, provides good clustering accuracy and is meanwhile much

  20. Using Quantitative Real-Time PCR to Detect MicroRNA Expression Profile During Embryonic Stem Cell Differentiation.

    Science.gov (United States)

    Pan, Xiaoping; Murashov, Alexander K; Stellwag, Edmund J; Zhang, Baohong

    2017-01-01

    Quantitative real-time PCR (qRT-PCR) is a reliable method to determine and monitor microRNA (miRNA) expression profiles in different cells, tissues, and organisms. Although there are several different strategies in performing qRT-PCR to determine miRNA expression, all of them have two steps in common: reverse transcription for obtaining cDNA from mature miRNA sequencing and standard real-time PCR for amplification of cDNA. This chapter demonstrates the application of quantitative real-time PCR for determining miRNA expression profiles during mouse embryonic stem cell differentiation. In this method, a mature miRNA sequence is first reverse transcribed into a long cDNA with a 40-50 nt miRNA-specific stem-loop primer; then, a standard real-time PCR reaction is performed for determining miRNA expression using a forward miRNA-specific primer and a universal reverse primer.

  1. Time-kill profiles and cell-surface morphological effects of crude ...

    African Journals Online (AJOL)

    a screw cap tube. Ethanol 50 % (v/v) was then added to the dried mycelium, and the mycelial suspension (100 mg/ml) was sonicated with a high Intensity Ultrasonic Processor (Model. VCX750, Newtown, CT, USA). This step was performed on ice as described by Sangdee et al. [18]. Time-kill assay. Time-kill assays were ...

  2. Effect of buccal dwell time on the pharmacokinetic profile of fentanyl buccal tablet.

    Science.gov (United States)

    Darwish, M; Kirby, M; Jiang, J G

    2007-09-01

    The time fentanyl buccal tablet (FBT) takes to completely dissolve after placement on the buccal mucosa (i.e., 'dwell time') could exceed the time to onset of analgesia. To examine the relationship between FBT dwell time and fentanyl pharmacokinetic parameters. This was a post hoc exploratory analysis of data from two randomized, open-label, crossover, pharmaco-kinetic studies that were designed to assess dose proportionality within the anticipated therapeutic dose range. Healthy adults received single FBT doses of 200-1080 microg in Study 1 (n = 28) and 270-1300 microg in Study 2 (n = 42). Assessments included buccal dwell time, defined as the duration of FBT presence in the oral cavity, and the following pharmacokinetic measures: maximum serum concentration (C(max)), time to C(max) (T(max)) and area under the concentration-time curve (AUC; exposure) from 0 minutes to median T(max) adjusted for the dose (T(max')) (AUC(0 T(max'))). Spontaneously reported adverse events were recorded. Mean buccal dwell time for FBT across the dose range varied from 14 to 25 minutes (range 3 - 62 minutes). There was no evidence of an association between FBT dwell time and values for T(max) (medians 45 - 60 minutes), dose-normalized C(max) (means 0.42-0.66 pg/ml/200 microg) or dose-normalized AUC(0 T(max')) (means 0.24-0.38 pg x h/ml/200 microg) over the range of FBT doses delivered. All adverse events reported were mild to moderate; none were unexpected or serious. The pharmacokinetic parameters of FBT did not appear to be related to its buccal dwell time.

  3. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-10-27 (NCEI Accession 0137365)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  4. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-11-05 (NCEI Accession 0137763)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  5. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 09/27/2011 (NCEI Accession 0077807)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  6. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 09/26/2013 (NODC Accession 0113334)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  7. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2013-10-24 (NODC Accession 0113793)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  8. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 07/04/2012 (NCEI Accession 0092436)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  9. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-10-08 (NCEI Accession 0136646)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  10. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-02-17 (NODC Accession 0125920)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  11. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2013-11-01 (NODC Accession 0113982)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  12. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2013-11-22 (NODC Accession 0114471)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  13. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-11-04 (NODC Accession 0123116)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  14. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-01-23 (NODC Accession 0116026)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  15. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-07-21 (NCEI Accession 0129906)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  16. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 02/28/2012 (NCEI Accession 0086083)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  17. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-12-23 (NODC Accession 0124256)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  18. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2013-10-29 (NODC Accession 0113945)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  19. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-04-29 (NODC Accession 0117941)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  20. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 02/27/2012 (NCEI Accession 0086050)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  1. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the month of June 2000 (NODC Accession 0000256)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  2. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 03/12/2013 (NODC Accession 0104239)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  3. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2013-10-24 (NODC Accession 0113751)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  4. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2013-11-25 (NODC Accession 0114474)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  5. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-06-12 (NODC Accession 0119415)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  6. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the month of December 1999 (NODC Accession 0000060)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  7. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-02-18 (NCEI Accession 0143274)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  8. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-08-09 (NCEI Accession 0156280)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  9. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-12-30 (NODC Accession 0124306)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  10. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 04/09/2013 (NODC Accession 0104407)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  11. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-04-19 (NCEI Accession 0147702)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  12. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 02/13/2013 (NODC Accession 0103263)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  13. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 05/27/2013 (NODC Accession 0107600)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  14. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 09/12/2011 (NCEI Accession 0076932)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  15. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 08/14/2012 (NODC Accession 0093752)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  16. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-02-05 (NODC Accession 0125585)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  17. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 10/25/2012 (NODC Accession 0099031)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  18. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 07/21/2011 (NCEI Accession 0074375)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  19. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 03/13/2012 (NCEI Accession 0086531)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  20. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-01-12 (NCEI Accession 0140525)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  1. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-02-23 (NCEI Accession 0144241)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  2. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 09/15/2011 (NCEI Accession 0077408)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  3. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 06/11/2013 (NODC Accession 0108245)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  4. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 03/05/2013 (NODC Accession 0104157)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  5. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-09-22 (NCEI Accession 0156633)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  6. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2013-12-16 (NODC Accession 0115398)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  7. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-08-28 (NCEI Accession 0131139)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  8. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 09/27/2012 (NODC Accession 0097970)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  9. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 1/6/2004 (NODC Accession 0001295)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  10. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 9/14/2006 (NCEI Accession 0002876)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  11. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 9/17/2007 (NCEI Accession 0033377)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  12. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 11/15/2010 ( (NODC Accession 0068583)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  13. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-03-24 (NCEI Accession 0145744)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  14. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 11/08/2010 (NODC Accession 0068332)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  15. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-03-01 (NCEI Accession 0144840)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  16. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 04/30/2013 (NODC Accession 0105461)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  17. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-05-12 (NODC Accession 0118477)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  18. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 11/27/2012 (NODC Accession 0099797)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  19. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-12-22 (NCEI Accession 0139495)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  20. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 08/22/2011 (NCEI Accession 0075277)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  1. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-08-22 (NODC Accession 0121314)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  2. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2013-11-13 (NODC Accession 0114408)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  3. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 01/07/2013 (NODC Accession 0101144)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  4. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-02-04 (NODC Accession 0116216)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  5. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2013-12-24 (NODC Accession 0115412)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  6. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 09/30/2013 (NODC Accession 0113483)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  7. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-11-14 (NCEI Accession 0137938)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  8. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-10-31 (NCEI Accession 0137473)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  9. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 11/07/2011 (NCEI Accession 0080665)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  10. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 10/27/2011 (NCEI Accession 0078576)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  11. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 02/14/2013 (NODC Accession 0103490)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  12. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 10/12/2004 (NCEI Accession 0001747)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  13. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-09-17 (NCEI Accession 0156612)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  14. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 09/27/2010 (NODC Accession 0067470)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  15. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-03-24 (NODC Accession 0126771)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  16. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-07-09 (NCEI Accession 0129879)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  17. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 10/11/2011 (NCEI Accession 0078520)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  18. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 11/20/2012 (NODC Accession 0099530)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  19. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-07-07 (NODC Accession 0119893)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  20. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 05/22/2012 (NCEI Accession 0089647)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  1. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 08/30/2010 (NODC Accession 0066834)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  2. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 12/30/2003 (NCEI Accession 0001279)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  3. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 1/14/2008 (NCEI Accession 0038180)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  4. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 12/15/2011 (NCEI Accession 0082384)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  5. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 12/20/2005 (NCEI Accession 0002473)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  6. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-06-09 (NODC Accession 0119337)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  7. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-07-24 (NODC Accession 0120617)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  8. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 10/12/2004 (NCEI Accession 0001742)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  9. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 09/20/2010 (NODC Accession 0067340)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  10. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-05-05 (NCEI Accession 0150186)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  11. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 11/30/2009 (NODC Accession 0059837)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  12. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 06/29/2009 (NODC Accession 0055294)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  13. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 9/12/2006 (NCEI Accession 0002837)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  14. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 3/30/2004 (NCEI Accession 0001406)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  15. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-01-12 (NODC Accession 0125189)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  16. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 9/24/2007 (NCEI Accession 0033401)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  17. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 9/23/2004 (NCEI Accession 0001722)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  18. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-06-08 (NCEI Accession 0129267)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  19. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 1/6/2005 (NCEI Accession 0001961)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  20. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 01/03/2011 (NODC Accession 0069636)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  1. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 12/18/2003 (NODC Accession 0001270)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  2. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-02-26 (NODC Accession 0126440)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  3. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-08-18 (NODC Accession 0121270)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  4. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 5/31/2005 (NCEI Accession 0002217)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  5. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-05-28 (NCEI Accession 0151845)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  6. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 09/19/2011 (NCEI Accession 0077530)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  7. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 05/14/2013 (NODC Accession 0106486)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  8. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-04-11 (NODC Accession 0117476)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  9. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-01-27 (NODC Accession 0125532)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  10. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 08/03/2011 (NCEI Accession 0074613)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  11. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 05/07/2012 (NCEI Accession 0089158)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  12. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-08-25 (NCEI Accession 0156411)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  13. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-01-21 (NODC Accession 0115913)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  14. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-10-06 (NCEI Accession 0134848)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  15. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 05/25/2011 (NCEI Accession 0073119)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  16. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 09/20/2012 (NODC Accession 0095599)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  17. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-04-09 (NCEI Accession 0146213)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  18. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-11-12 (NODC Accession 0123221)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  19. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 01/03/2012 (NCEI Accession 0083185)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  20. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 05/14/2012 (NCEI Accession 0089365)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  1. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 10/24/2011 (NCEI Accession 0078568)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  2. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2013-12-03 (NODC Accession 0115359)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  3. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 06/10/2013 (NODC Accession 0108211)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  4. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-07-29 (NODC Accession 0120700)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  5. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2013-11-26 (NODC Accession 0115355)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  6. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-10-03 (NCEI Accession 0132121)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  7. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-02-19 (NCEI Accession 0143634)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  8. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 04/23/2013 (NODC Accession 0104434)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  9. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-03-27 (NODC Accession 0117353)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  10. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 07/26/2011 (NCEI Accession 0074536)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  11. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-06-02 (NCEI Accession 0152452)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  12. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-07-21 (NODC Accession 0120510)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  13. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 11/23/2004 (NCEI Accession 0001907)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  14. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-03-05 (NCEI Accession 0145088)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  15. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-04-08 (NODC Accession 0117460)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  16. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-05-22 (NODC Accession 0118681)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  17. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 11/15/2012 (NODC Accession 0099429)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  18. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 07/18/2013 (NODC Accession 0110790)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  19. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-03-22 (NCEI Accession 0145654)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  20. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 01/23/2012 (NCEI Accession 0084460)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  1. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 02/18/2013 (NODC Accession 0103870)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  2. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2013-10-25 (NODC Accession 0113855)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  3. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-05-11 (NCEI Accession 0127930)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  4. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 12/19/2011 (NCEI Accession 0082521)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  5. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 03/14/2013 (NODC Accession 0104258)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  6. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 09/22/2011 (NCEI Accession 0077569)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  7. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 05/24/2011 (NCEI Accession 0073088)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  8. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-12-15 (NCEI Accession 0139308)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  9. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-07-19 (NCEI Accession 0155928)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  10. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-08-25 (NCEI Accession 0131125)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  11. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 11/15/2011 (NCEI Accession 0081137)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  12. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 12/12/2011 (NCEI Accession 0082293)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  13. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 12/17/2012 (NODC Accession 0100433)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  14. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-06-15 (NCEI Accession 0129416)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  15. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 11/13/2012 (NODC Accession 0099417)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  16. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-06-28 (NCEI Accession 0154496)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  17. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 01/21/2013 (NODC Accession 0101530)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  18. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-03-31 (NCEI Accession 0145906)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  19. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2013-11-04 (NODC Accession 0114206)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  20. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 09/16/2013 (NODC Accession 0112961)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  1. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 01/15/2013 (NODC Accession 0101434)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  2. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-05-31 (NCEI Accession 0152443)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  3. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 02/04/2013 (NODC Accession 0101842)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  4. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-12-01 (NCEI Accession 0138536)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  5. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-09-26 (NCEI Accession 0131990)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  6. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 09/04/2013 (NODC Accession 0112722)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  7. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 07/15/2013 (NODC Accession 0110495)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  8. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-04-23 (NCEI Accession 0148079)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  9. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 01/05/2012 (NCEI Accession 0083247)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  10. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 03/25/2013 (NODC Accession 0104298)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  11. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 08/18/2011 (NCEI Accession 0075276)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  12. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-02-11 (NCEI Accession 0142200)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  13. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-03-25 (NCEI Accession 0145793)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  14. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 05/06/2013 (NODC Accession 0105759)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  15. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-01-09 (NCEI Accession 0140350)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  16. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 05/09/2011 (NCEI Accession 0072669)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  17. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 02/11/2013 (NODC Accession 0102923)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  18. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 08/29/2013 (NODC Accession 0112561)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  19. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 07/30/2013 (NODC Accession 0111329)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  20. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 09/23/2013 (NODC Accession 0113241)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  1. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-07-03 (NCEI Accession 0129871)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  2. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-04-27 (NCEI Accession 0127420)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  3. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-07-08 (NCEI Accession 0129536)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  4. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-07-02 (NCEI Accession 0129841)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  5. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-06-30 (NCEI Accession 0129531)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  6. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-04-23 (NCEI Accession 0127401)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  7. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 05/13/2013 (NODC Accession 0106411)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  8. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 10/17/2012 (NODC Accession 0098724)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  9. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 09/25/2012 (NODC Accession 0097922)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  10. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-09-02 (NODC Accession 0121575)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  11. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-01-07 (NODC Accession 0115675)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  12. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 06/27/2013 (NODC Accession 0109835)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  13. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 11/17/2011 (NCEI Accession 0081201)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  14. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-04-12 (NCEI Accession 0146303)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  15. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-01-13 (NODC Accession 0125197)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  16. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 05/15/2012 (NCEI Accession 0089366)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  17. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 09/17/2013 (NODC Accession 0112963)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  18. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-09-29 (NCEI Accession 0132019)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  19. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 12/06/2011 (NCEI Accession 0082190)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  20. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-01-20 (NODC Accession 0125417)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  1. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-05-05 (NCEI Accession 0127551)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  2. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-08-11 (NODC Accession 0121226)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  3. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-11-17 (NODC Accession 0123256)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  4. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 09/01/2011 (NCEI Accession 0075307)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  5. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-06-30 (NCEI Accession 0155188)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  6. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-01-26 (NODC Accession 0125509)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  7. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-05-06 (NODC Accession 0118357)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  8. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 10/02/2012 (NODC Accession 0098097)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  9. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-12-05 (NCEI Accession 0138740)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  10. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 07/31/2012 (NODC Accession 0093332)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  11. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 10/12/2011 (NCEI Accession 0078522)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  12. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 5/2/2006 (NCEI Accession 0002656)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  13. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 02/23/2012 (NCEI Accession 0085833)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  14. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-07-16 (NCEI Accession 0129889)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  15. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 7/11/2006 (NCEI Accession 0002746)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  16. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 8/27/2007 (NCEI Accession 0032357)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  17. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-05-13 (NODC Accession 0118496)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  18. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 4/14/2005 (NCEI Accession 0002130)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  19. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 11/18/2003 (NCEI Accession 0001232)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  20. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 03/11/2013 (NODC Accession 0104238)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  1. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 01/10/2011 (NODC Accession 0069935)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  2. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 07/08/2013 (NODC Accession 0110253)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  3. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2/5/2004 (NCEI Accession 0001331)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  4. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 6/7/2005 (NCEI Accession 0002220)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  5. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-02-02 (NODC Accession 0125568)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  6. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 01/28/2013 (NODC Accession 0101749)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  7. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-09-16 (NODC Accession 0122114)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  8. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 06/01/2009 (NODC Accession 0054209)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  9. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-12-11 (NODC Accession 0123638)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  10. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2/9/2006 (NCEI Accession 0002535)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  11. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 8/4/2004 (NCEI Accession 0001652)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  12. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 1/13/2005 (NCEI Accession 0001975)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  13. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 7/15/2004 (NCEI Accession 0001625)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  14. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the month of July 2000 (NODC Accession 0000257)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  15. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 5/18/2004 (NCEI Accession 0001463)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  16. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-07-29 (NCEI Accession 0130006)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  17. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 9/22/2005 (NCEI Accession 0002381)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  18. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 05/17/2010 (NODC Accession 0064381)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  19. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2/24/2005 (NCEI Accession 0002038)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  20. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2013-11-28 (NODC Accession 0115357)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  1. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 08/03/2009 (NODC Accession 0056405)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  2. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2/7/2006 (NCEI Accession 0002530)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  3. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 11/29/2012 (NODC Accession 0099813)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  4. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 12/27/2010 (NODC Accession 0069610)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  5. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 01/22/2013 (NODC Accession 0101663)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  6. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 11/15/2004 (NCEI Accession 0001899)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  7. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 04/11/2011 (NODC Accession 0072067)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  8. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 10/04/2010 (NODC Accession 0067648)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  9. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-03-24 (NODC Accession 0117347)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  10. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-12-25 (NCEI Accession 0139575)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  11. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 08/13/2012 (NODC Accession 0093607)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  12. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 05/05/2011 (NCEI Accession 0072625)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  13. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 03/27/2012 (NCEI Accession 0087106)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  14. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 12/20/2012 (NODC Accession 0100509)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  15. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 08/30/2012 (NODC Accession 0094748)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  16. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-06-03 (NCEI Accession 0129065)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  17. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 02/14/2012 (NCEI Accession 0085124)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  18. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-10-22 (NCEI Accession 0137141)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  19. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 04/03/2013 (NODC Accession 0104386)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  20. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 06/07/2012 (NCEI Accession 0090460)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  1. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2009-02-02 (NODC Accession 0050190)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  2. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 12/21/2009 (NODC Accession 0060586)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  3. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the month of April 2000 (NODC Accession 0000254)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  4. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-01-21 (NODC Accession 0115903)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  5. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-09-28 (NCEI Accession 0156647)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  6. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-10-07 (NODC Accession 0122516)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  7. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-01-19 (NCEI Accession 0140928)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  8. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-08-07 (NCEI Accession 0130421)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  9. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 02/28/2013 (NODC Accession 0104035)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  10. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-12-19 (NCEI Accession 0139469)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  11. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-07-08 (NODC Accession 0119917)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  12. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-10-20 (NCEI Accession 0137087)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  13. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-08-06 (NCEI Accession 0156243)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  14. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-08-19 (NODC Accession 0121283)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  15. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 04/30/2012 (NCEI Accession 0088994)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  16. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-12-17 (NCEI Accession 0139400)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  17. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-07-06 (NCEI Accession 0129872)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  18. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 09/05/2012 (NODC Accession 0094851)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  19. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 08/28/2013 (NODC Accession 0112531)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  20. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 04/25/2013 (NODC Accession 0104695)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  1. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 03/15/2012 (NCEI Accession 0086635)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  2. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-04-14 (NCEI Accession 0146679)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  3. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-10-16 (NODC Accession 0122660)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  4. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-10-06 (NODC Accession 0122513)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  5. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-12-24 (NCEI Accession 0139552)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  6. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-05-07 (NCEI Accession 0127819)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  7. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2013-11-22 (NODC Accession 0114470)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  8. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-11-21 (NCEI Accession 0138175)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  9. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 09/12/2013 (NODC Accession 0112888)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  10. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 07/02/2013 (NODC Accession 0109898)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  11. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-07-22 (NODC Accession 0120530)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  12. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-10-15 (NCEI Accession 0136937)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  13. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-03-20 (NODC Accession 0117307)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  14. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 09/24/2012 (NODC Accession 0096720)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  15. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 08/24/2012 (NODC Accession 0094090)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  16. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 12/24/2012 (NODC Accession 0100549)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  17. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-11-25 (NODC Accession 0123319)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  18. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-09-08 (NCEI Accession 0131422)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  19. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted since 1999-10-04

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  20. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 1/10/2006 (NCEI Accession 0002493)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  1. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2013-12-12 (NODC Accession 0115397)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  2. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 6/30/2005 (NCEI Accession 0002260)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  3. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 4/18/2005 (NCEI Accession 0002131)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  4. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 4/25/2005 (NCEI Accession 0002136)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  5. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 11/18/2004 (NCEI Accession 0001901)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  6. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 7/17/2006 (NCEI Accession 0002755)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  7. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 4/23/2007 (NCEI Accession 0014886)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  8. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 3/23/2004 (NCEI Accession 0001396)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  9. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 4/6/2006 (NCEI Accession 0002625)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  10. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 6/23/2008 (NCEI Accession 0042994)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  11. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 07/12/2011 (NCEI Accession 0074224)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  12. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 10/21/2003 (NCEI Accession 0001203)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  13. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 05/22/2013 (NODC Accession 0107448)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  14. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-05-03 (NCEI Accession 0149766)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  15. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-06-05 (NODC Accession 0119184)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  16. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-11-19 (NCEI Accession 0138155)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  17. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 10/01/2013 (NODC Accession 0113518)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  18. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 06/17/2013 (NODC Accession 0108834)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  19. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-09-13 (NCEI Accession 0156584)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  20. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 08/26/2013 (NODC Accession 0112417)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  1. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 06/13/2013 (NODC Accession 0108362)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  2. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 11/25/2003 (NCEI Accession 0001242)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  3. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2016-05-07 (NCEI Accession 0150387)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  4. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 10/2/2006 (NCEI Accession 0009913)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  5. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 7/2/2004 (NCEI Accession 0001605)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  6. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 03/19/2012 (NCEI Accession 0086806)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  7. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 07/12/2012 (NODC Accession 0092526)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  8. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted the week of 4/14/2008 (NCEI Accession 0041368)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  9. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 9/27/2004 (NCEI Accession 0001727)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  10. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 3/21/2006 (NCEI Accession 0002608)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  11. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 1/12/2006 (NCEI Accession 0002495)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  12. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 11/19/2012 (NODC Accession 0099451)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  13. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-12-30 (NCEI Accession 0139725)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  14. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 10/23/2003 (NCEI Accession 0001205)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  15. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2014-10-02 (NODC Accession 0122408)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  16. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-04-13 (NODC Accession 0127356)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  17. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 4/19/2005 (NCEI Accession 0002133)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  18. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 12/20/2004 (NCEI Accession 0001945)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  19. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted on 2015-11-17 (NCEI Accession 0138006)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...

  20. Real-time profile data assembled by Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP) and dates range from 25 April 2000 to 27 October 2000 (NODC Accession 0000327)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles reported for the world oceans in near real-time from the Global...