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Sample records for profile system losses

  1. IFMIF-LIPAc Beam Diagnostics. Profiling and Loss Monitoring Systems

    International Nuclear Information System (INIS)

    Egberts, J.

    2012-01-01

    The IFMIF accelerator will accelerate two 125 mA continuous wave (cw) deuteron beams up to 40 MeV and blasts them onto a liquid lithium target to release neutrons. The very high beam power of 10 MW pose unprecedented challenges for the accelerator development. Therefore, it was decided to build a prototype accelerator, the Linear IFMIF Prototype Accelerator (LIPAc), which has the very same beam characteristic, but is limited to 9 MeV only. In the frame of this thesis, diagnostics devices for IFMIF and LIPAc have been developed. The diagnostics devices consist of beam loss monitors and interceptive as well as non-interceptive profile monitors. For the beam loss monitoring system, ionization chambers and diamond detectors have been tested and calibrated for neutron and γ radiation in the energy range expected at LIPAc. During these tests, for the first time, diamond detectors were successfully operated at cryogenic temperatures. For the interceptive profilers, thermal simulations were performed to ensure safe operation. For the non-interceptive profiler, Ionization Profile Monitors (IPMs) were developed. A prototype has been built and tested, and based on the findings, the final IPMs were designed and built. To overcome the space charge of accelerator beam, a software algorithm was written to reconstruct the actual beam profile. (author) [fr

  2. Periodontal profile classes predict periodontal disease progression and tooth loss.

    Science.gov (United States)

    Morelli, Thiago; Moss, Kevin L; Preisser, John S; Beck, James D; Divaris, Kimon; Wu, Di; Offenbacher, Steven

    2018-02-01

    Current periodontal disease taxonomies have limited utility for predicting disease progression and tooth loss; in fact, tooth loss itself can undermine precise person-level periodontal disease classifications. To overcome this limitation, the current group recently introduced a novel patient stratification system using latent class analyses of clinical parameters, including patterns of missing teeth. This investigation sought to determine the clinical utility of the Periodontal Profile Classes and Tooth Profile Classes (PPC/TPC) taxonomy for risk assessment, specifically for predicting periodontal disease progression and incident tooth loss. The analytic sample comprised 4,682 adult participants of two prospective cohort studies (Dental Atherosclerosis Risk in Communities Study and Piedmont Dental Study) with information on periodontal disease progression and incident tooth loss. The PPC/TPC taxonomy includes seven distinct PPCs (person-level disease pattern and severity) and seven TPCs (tooth-level disease). Logistic regression modeling was used to estimate relative risks (RR) and 95% confidence intervals (CI) for the association of these latent classes with disease progression and incident tooth loss, adjusting for examination center, race, sex, age, diabetes, and smoking. To obtain personalized outcome propensities, risk estimates associated with each participant's PPC and TPC were combined into person-level composite risk scores (Index of Periodontal Risk [IPR]). Individuals in two PPCs (PPC-G: Severe Disease and PPC-D: Tooth Loss) had the highest tooth loss risk (RR = 3.6; 95% CI = 2.6 to 5.0 and RR = 3.8; 95% CI = 2.9 to 5.1, respectively). PPC-G also had the highest risk for periodontitis progression (RR = 5.7; 95% CI = 2.2 to 14.7). Personalized IPR scores were positively associated with both periodontitis progression and tooth loss. These findings, upon additional validation, suggest that the periodontal/tooth profile classes and the derived

  3. Health-related profiles of people with lower limb loss.

    Science.gov (United States)

    Amtmann, Dagmar; Morgan, Sara J; Kim, Jiseon; Hafner, Brian J

    2015-08-01

    To construct profiles of self-reported health indicators to examine differences and similarities between people with lower limb loss and a normative sample (hereafter called the norm) and to compare health indicators between subgroups based on level and etiology of limb loss. Survey. General community. Adults with unilateral lower limb loss (N=1091) participated in this study. Eligibility criteria included lower limb loss due to trauma or dysvascular complications and regular use of a prosthesis. Not applicable. The Patient-Reported Outcomes Measurement Information System 29-item Health Profile version 1.0 measures physical function, pain interference, fatigue, sleep disturbance, anxiety, depression, and satisfaction with participation in social roles. The norm includes 5239 individuals representative of the U.S. general population in sex, age, race, ethnicity, and education. People with lower limb loss reported statistically significantly worse physical function, pain interference, and satisfaction with participation in social roles and significantly less fatigue than did the norm. People with transfemoral (ie, above-knee) amputation significantly differed in physical function from people with transtibial (ie, below-knee) amputation. Similarly, people with amputation due to trauma and dysvascular etiology significantly differed in physical function and satisfaction with social roles after adjusting for relevant clinical characteristics. People with lower limb loss generally report worse physical function, pain interference, and satisfaction with social roles than do the norm. People with dysvascular amputation reported worse physical function and satisfaction with social roles than did people with traumatic amputation. Health indicator profiles are an efficient way of providing clinically meaningful information about numerous aspects of self-reported health in people with lower limb loss. Copyright © 2015 American Congress of Rehabilitation Medicine. Published by

  4. Evaluating the effect placement capacitor and distributed photovoltaic generation for power system losses minimization in radial distribution system

    Science.gov (United States)

    Rahman, Yuli Asmi; Manjang, Salama; Yusran, Ilham, Amil Ahmad

    2018-03-01

    Power loss minimization have many advantagess to the distribution system radial among others reduction of power flow in feeder lines, freeing stress on feeder loading, deterrence of power procurement from the grid and also the cost of loss compensating instruments. This paper, presents capacitor and photovoltaic (PV) placement as alternative means to decrease power system losses. The paper aims to evaluate the best alternative for decreasing power system losses and improving voltage profile in the radial distribution system. To achieve the objectives of paper, they are used three cases tested by Electric Transient and Analysis Program (ETAP) simulation. Firstly, it performs simulation of placement capacitor. Secondly, simulated placement of PV. Lastly, it runs simulation of placement capacitor and PV simultaneously. The simulations were validated using the IEEE 34-bus test system. As a result, they proved that the installation of capacitor and PV integration simultaneously leading to voltage profile correction and power losses minimization significantly.

  5. Fuzzy Adaptive Particle Swarm Optimization for Power Loss Minimisation in Distribution Systems Using Optimal Load Response

    DEFF Research Database (Denmark)

    Hu, Weihao; Chen, Zhe; Bak-Jensen, Birgitte

    2014-01-01

    Consumers may decide to modify the profile of their demand from high price periods to low price periods in order to reduce their electricity costs. This optimal load response to electricity prices for demand side management generates different load profiles and provides an opportunity to achieve...... power loss minimization in distribution systems. In this paper, a new method to achieve power loss minimization in distribution systems by using a price signal to guide the demand side management is proposed. A fuzzy adaptive particle swarm optimization (FAPSO) is used as a tool for the power loss...

  6. Development of Cold Neutron Depth Profiling System at HANARO

    International Nuclear Information System (INIS)

    Park, B. G.; Choi, H. D.; Sun, G. M.

    2012-01-01

    The depth profiles of intentional or intrinsic constituents of a sample provide valuable information for the characterization of materials. A number of analytical techniques for depth profiling have been developed. Neutron Depth Profiling (NDP) system which was developed by Ziegler et al. is one of the leading analytical techniques. In NDP, a thermal or cold neutron beam passes through a material and interacts with certain isotopes that are known to emit monoenergetic-charged particle remaining a recoil nucleus after neutron absorption. The depth is obtained from the energy loss of those charged particles escaping surface of substrate material. For various applications of NDP technique, the Cold Neutron Depth Profiling System (CN-NDP) was developed at a neutron guide CG1 installed at the HANARO cold neutron source. In this study the design features of the cold neutron beam and target chamber for the CN-NDP system are given. Also, some experiments for the performance tests of the CN-NDP system are described

  7. Impact of distributed generators on the power loss and voltage profile of sub-transmission network

    Directory of Open Access Journals (Sweden)

    A.S.O. Ogunjuyigbe

    2016-05-01

    Full Text Available This paper presents the impact of distributed generator (DG on the power loss and voltage profile of sub-transmission network at different penetration levels (PLs. The various DG technologies are modeled based on their electrical output characteristics. Voltage profile index which allows a single value to represent how well the voltage matches the ideal value is developed. The index allows a fair comparison of the voltage profile obtained from different scenarios. The extent to which DGs affect power losses and voltage profile depend on the type of DG technology, PL and the location in which the DG is connected to the grid. The integration of DGs reduces power losses on the network, however, as the PL increases, the power losses begin to increase. A PL of 50–75% is achieved on 69 kV voltage level and 25–50% penetration on 13.8 kV voltage level without an increase in the power loss. Also more DG can be integrated into the network at point of common connection of higher voltage level compared to the low voltage level.

  8. Electron density profile in multilayer systems

    International Nuclear Information System (INIS)

    Toekesi, K.

    2004-01-01

    Complete text of publication follows. Electron energy loss spectroscopy (EELS) has been used extensively to study the multilayer systems, where the thickness of layers are in the nanometer range. These studies has received considerable attention because of its technological interest, for example in the nanotechnology. On the most fundamental level, its importance is derived from the basic physics that is involved. One key quantities of interest is the response of a many-body system to an external perturbation: How act and how modify the interface between the solid-solid or solid-vacuum the excitations in the solid and in the vicinity of the interfaces. In this work, as a starting point of such investigations we calculated the electron density profile for multilayer systems. Our approach employs the time-dependent density functional theory (TDDFT), that is, the solution of a time-dependent Schroedinger equation in which the potential and forces are determined selfconsistently from the dynamics governed by the Schroedinger equation. We treat the problem in TDDFT at the level of the local-density approximation (LDA). Later, the comparison of experimentally obtained loss functions and the theory, based on our TDDFT calculations can provide deeper understanding of surface physics. We performed the calculations for half-infinite samples characterized by r s =1.642 and r s =1.997. We also performed the calculations for double layer systems. The substrate was characterized by r s =1.997 and the coverage by r s =1.642. Fig. 1. shows the obtained electron density profile in LDA approximation. Because of the sharp cutoff of electronic wave vectors at the Fermi surface, the densities in the interior exhibit slowly decaying Friedel oscillations. To highlight the Friedel oscillation we enlarged the electron density profile in Fig. 1a. and Fig. 1b. The work was supported by the Hungarian Scientific Research Found: OTKA No. T038016, the grant 'Bolyai' from the Hungarian Academy of

  9. Measurements of Beam Ion Loss from the Compact Helical System

    International Nuclear Information System (INIS)

    Darrow, D.S.; Isobe, M.; Kondo, Takashi; Sasao, M.

    2010-01-01

    Beam ion loss from the Compact Helical System (CHS) has been measured with a scintillator-type probe. The total loss to the probe, and the pitch angle and gyroradius distributions of that loss, have been measured as various plasma parameters were scanned. Three classes of beam ion loss were observed at the probe position: passing ions with pitch angles within 10o of those of transition orbits, ions on transition orbits, and ions on trapped orbits, typically 15o or more from transition orbits. Some orbit calculations in this geometry have been performed in order to understand the characteristics of the loss. Simulation of the detector signal based upon the following of orbits from realistic beam deposition profiles is not able to reproduce the pitch angle distribution of the losses measured. Consequently it is inferred that internal plasma processes, whether magnetohydrodynamic modes, radial electric fields, or plasma turbulence, move previously confined beam ions to transition orbits, resulting in their loss.

  10. Combined effect of CVR and penetration of DG in the voltage profile and losses of lowvoltage secondary distribution networks

    Science.gov (United States)

    Bokhari, Abdullah

    Demarcations between traditional distribution power systems and distributed generation (DG) architectures are increasingly evolving as higher DG penetration is introduced in the system. The concerns in existing electric power systems (EPSs) to accommodate less restrictive interconnection policies while maintaining reliability and performance of power delivery have been the major challenge for DG growth. In this dissertation, the work is aimed to study power quality, energy saving and losses in a low voltage distributed network under various DG penetration cases. Simulation platform suite that includes electric power system, distributed generation and ZIP load models is implemented to determine the impact of DGs on power system steady state performance and the voltage profile of the customers/loads in the network under the voltage reduction events. The investigation designed to test the DG impact on power system starting with one type of DG, then moves on multiple DG types distributed in a random case and realistic/balanced case. The functionality of the proposed DG interconnection is designed to meet the basic requirements imposed by the various interconnection standards, most notably IEEE 1547, public service commission, and local utility regulation. It is found that implementation of DGs on the low voltage secondary network would improve customer's voltage profile, system losses and significantly provide energy savings and economics for utilities. In a network populated with DGs, utility would have a uniform voltage profile at the customers end as the voltage profile becomes more concentrated around targeted voltage level. The study further reinforced the concept that the behavior of DG in distributed network would improve voltage regulation as certain percentage reduction on utility side would ensure uniform percentage reduction seen by all customers and reduce number of voltage violations.

  11. Impact of intermittent fasting on the lipid profile: Assessment associated with diet and weight loss.

    Science.gov (United States)

    Santos, Heitor O; Macedo, Rodrigo C O

    2018-04-01

    Intermittent fasting, whose proposed benefits include the improvement of lipid profile and the body weight loss, has gained considerable scientific and popular repercussion. This review aimed to consolidate studies that analyzed the lipid profile in humans before and after intermittent fasting period through a detailed review; and to propose the physiological mechanism, considering the diet and the body weight loss. Normocaloric and hypocaloric intermittent fasting may be a dietary method to aid in the improvement of the lipid profile in healthy, obese and dyslipidemic men and women by reducing total cholesterol, LDL, triglycerides and increasing HDL levels. However, the majority of studies that analyze the intermittent fasting impacts on the lipid profile and body weight loss are observational based on Ramadan fasting, which lacks large sample and detailed information about diet. Randomized clinical trials with a larger sample size are needed to evaluate the IF effects mainly in patients with dyslipidemia. Copyright © 2018 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.

  12. Exergy Rate Profile of Multicomponent Distillation System

    Directory of Open Access Journals (Sweden)

    Kehinde Adewale Adesina

    2016-07-01

    Full Text Available Exergy rate profiles, exergetic efficiency and irreversibility were used to examine the driving forces in multicomponent distillation system with the view to identifying feasible and efficient operating parameters. The mixture used comprised of 5% propane, 15% iso-butane, 25% nbutane, 20% iso-pentane and 35% n-pentane. Operating variables were feed temperature (-30 oC and -80 oC, pressure (800 kPa and 1200 kPa, and reflux-ratio (2 and 6. Stage-by-stage system exergy analysis was estimated. Column profiles of base case -30 oC, -80 oC, -30 oC-reflus ratio 6, -80 oC reflux ratio 6 and base case reflux ratio 6 did not crossed thus are thermodynamically feasible. Base case -30 oC-reflux ratio 2, -80 oC-reflux ratio 2, and base case-reflux ratio 2 were crossed and constricted and are infeasible. Base case results gave efficiency of 81.7% at depropanizer and 65.2% at debutanizer. Base cases sensitivity results with -30 oC, -80 oC and reflux ratio 6, efficiency range 57.40 – 70% and 65.20% - 54.90% for depropanizer and debutanizer respectively. Spitted cases gave 81.7% and 62.20% with more scatter profiles. Splitted feed base case -30 oC design gave the lowest overall system exergy loss rate of 1.12E+6 and efficiency of 95.70%. Design feasible parameters, system efficiency and irreversibility which form basis

  13. MOSFET Loss Evaluation for a Low-Power Stand-Alone Photovoltaic-LED System

    DEFF Research Database (Denmark)

    Mira Albert, Maria del Carmen; Knott, Arnold; Andersen, Michael A. E.

    2015-01-01

    This paper presents a performance evaluation and comparison of state-of-the-art low voltage Si MOSFETs for a stand-alone photovoltaic-LED Light to Light (LtL) system. The complete system is formed by two cascaded converters that will be optimized for a determined solar irradiation and LED...... illumination profiles. The comparison is performed based on dynamic characterization and evaluation of the devices energy loss at different current levels....

  14. Reactor protection system software test-case selection based on input-profile considering concurrent events and uncertainties

    International Nuclear Information System (INIS)

    Khalaquzzaman, M.; Lee, Seung Jun; Cho, Jaehyun; Jung, Wondea

    2016-01-01

    Recently, the input-profile-based testing for safety critical software has been proposed for determining the number of test cases and quantifying the failure probability of the software. Input-profile of a reactor protection system (RPS) software is the input which causes activation of the system for emergency shutdown of a reactor. This paper presents a method to determine the input-profile of a RPS software which considers concurrent events/transients. A deviation of a process parameter value begins through an event and increases owing to the concurrent multi-events depending on the correlation of process parameters and severity of incidents. A case of reactor trip caused by feedwater loss and main steam line break is simulated and analyzed to determine the RPS software input-profile and estimate the number of test cases. The different sizes of the main steam line breaks (e.g., small, medium, large break) with total loss of feedwater supply are considered in constructing the input-profile. The uncertainties of the simulation related to the input-profile-based software testing are also included. Our study is expected to provide an option to determine test cases and quantification of RPS software failure probability. (author)

  15. Surface waves at the interface with an antisymmetric gain/loss profile

    International Nuclear Information System (INIS)

    Ctyroky, Jiri; Kuzmiak, Vladimir; Eyderman, Sergey

    2010-01-01

    We studied properties of strongly guiding two-mode waveguides with antisymmetric gain/loss profile which constitute photonic analogues of quantum mechanical structures with parity-time symmetry breaking. For both TE and TM polarizations, the dependences of effective indices of the guided modes vs. gain/loss coefficient exhibit a degenerate critical point that defines two regimes with profoundly different behavior. In addition, we have shown that the interface between the two media supports propagation of a strongly confined non-attenuated TM polarized surface wave. We examined the properties of the surface wave obtained by both the modal and FDTD method and discuss the differences between the results obtained by both techniques as both the material and geometrical parameters are varied.

  16. Identification of intestinal loss of a drug through physiologically based pharmacokinetic simulation of plasma concentration-time profiles.

    Science.gov (United States)

    Peters, Sheila Annie

    2008-01-01

    Despite recent advances in understanding of the role of the gut as a metabolizing organ, recognition of gut wall metabolism and/or other factors contributing to intestinal loss of a compound has been a challenging task due to the lack of well characterized methods to distinguish it from first-pass hepatic extraction. The implications of identifying intestinal loss of a compound in drug discovery and development can be enormous. Physiologically based pharmacokinetic (PBPK) simulations of pharmacokinetic profiles provide a simple, reliable and cost-effective way to understand the mechanisms underlying pharmacokinetic processes. The purpose of this article is to demonstrate the application of PBPK simulations in bringing to light intestinal loss of orally administered drugs, using two example compounds: verapamil and an in-house compound that is no longer in development (referred to as compound A in this article). A generic PBPK model, built in-house using MATLAB software and incorporating absorption, metabolism, distribution, biliary and renal elimination models, was employed for simulation of concentration-time profiles. Modulation of intrinsic hepatic clearance and tissue distribution parameters in the generic PBPK model was done to achieve a good fit to the observed intravenous pharmacokinetic profiles of the compounds studied. These optimized clearance and distribution parameters are expected to be invariant across different routes of administration, as long as the kinetics are linear, and were therefore employed to simulate the oral profiles of the compounds. For compounds with reasonably good solubility and permeability, an area under the concentration-time curve for the simulated oral profile that far exceeded the observed would indicate some kind of loss in the intestine. PBPK simulations applied to compound A showed substantial loss of the compound in the gastrointestinal tract in humans but not in rats. This accounted for the lower bioavailability of the

  17. Thermodynamic evaluation of distillation columns using exergy loss profiles: a case study on the crude oil atmospheric distillation column

    Energy Technology Data Exchange (ETDEWEB)

    Tarighaleslami, Amir Hossein [Mahshahr Branch, Islamic Azad University, Chemical Engineering Faculty, Mahshar, Khouzestan (Iran, Islamic Republic of); Omidkhah, Mohammad Reza [Tarbiat Modares University, Chemical Engineering Department, Faculty of Engineering, Tehran (Iran, Islamic Republic of); Ghannadzadeh, Ali [University of Toulouse, Department of Process and System Engineering, Chemical Engineering Laboratory, Toulouse (France); Hoseinzadeh Hesas, Roozbeh [University of Malaya, Chemical Engineering Department, Faculty of Engineering, Kuala Lumpur (Malaysia)

    2012-06-15

    This paper presents a case study on the crude oil atmospheric distillation column of Tabriz refinery plant to show the applicability of exergy loss profiles in thermodynamic examination of the different retrofit options. The atmospheric distillation column of Tabriz refinery has been revamped as a consequence of increase of the plant capacity to 100,000 bpd. To cover the deficit of feedstock of the revamped unit, a blend of the existing feedstock with imported crude oil is used as a feedstock. However, to investigate how the blend of these two different types of crudes as a feedstock has an influence on the operating conditions, the examination of the column is needed. Exergy as a comprehensive thermodynamic property which translates the temperature, pressure and composition change into a common unit has been chosen to evaluate the distillation column thermodynamically. Furthermore, the exergy loss profile of the base case serves as a scoping tool to pinpoint the source of inefficiencies. Then, the exergy loss profile as a screening tool has found the retrofit options which are likely to yield greatest energy saving from a list of retrofit options proposed by the industrial partner. In the presented case study, the exergy loss profile identifies the best retrofit option with 17.16% reduction in exergy losses, which finally lead to 3.6% reduction of primary fuel demand. (orig.)

  18. Identification of LHC beam loss mechanism: a deterministic treatment of loss patterns

    International Nuclear Information System (INIS)

    Marsili, A.

    2012-01-01

    The goal of this work was to identify patterns in the beam loss profiles, both in their spatial distribution and time evolution. CERN's Large Hadron Collider (LHC) is the largest device ever built, with a total circumference of 26.7 km; and it is the most powerful accelerator ever, both in beam energy and beam intensity. The main magnets are superconducting, and contain the particles into two counter circulating beams which collide in four interaction points. CERN and the LHC will be described in chapter 1. The superconducting magnets of the LHC have to be protected against particle losses. Depending on the number of lost particles, the coils of the magnets could become normal conducting and/or will be damaged. To avoid these events a beam loss monitoring (BLM) system was installed to measure the particle loss rates. If the predefined safe thresholds of loss rates are exceeded, the beams are directed out of the accelerator ring towards the beam dump. The detectors of the BLM system are mainly ionization chambers located outside of the cryostats. In total, about 3600 ionisation chambers are installed. Further challenges include the high dynamical range of losses (chamber currents ranging between 2 pA and 1 mA). The BLM system will be further described in chapter 2. The subject of this thesis is to study the loss patterns and nd the origin of the losses in a deterministic way, by comparing measured losses to well understood loss scenarios. This is done through a case study: different techniques were used on a restrained set of loss scenarios, as a proof of concept of the possibility to extract information from a loss profile. Finding the origin of the losses should allow acting in response. A justification of the doctoral work will be given at the end of chapter 2. This thesis will then focus on the theoretical understanding and the implementation of the decomposition of a measured loss profile as a linear combination of the reference scenarios; and the evaluation of

  19. Systemic causes of hair loss.

    Science.gov (United States)

    Lin, Richard L; Garibyan, Lilit; Kimball, Alexandra B; Drake, Lynn A

    2016-09-01

    Hair loss is both a common chief complaint by patients and a clinical challenge for physicians, especially general practitioners, yet few dermatological problems yield as much patient satisfaction when resolved as hair loss. The diagnosis is often attributed to androgen-related hair loss, while other causes, some of which are life-threatening but treatable, are overlooked. We searched for relevant literature on hair loss and supported these findings with our clinical experience to identify seven major systemic etiologies of hair loss, ranging from infectious agents to consumption of unsafe supplements. Many causes are only described in the literature through case studies, though some original articles and meta-analyses are available. Careful history taking, proper examination techniques, and judicious use of laboratory tests are essential to reach at the correct diagnosis in a cost-effective manner when performing patient work-up. Such methodical evaluation of hair loss can result in the appropriate treatment plan and provide significant patient satisfaction. Key messages Hair loss is a common chief complaint and a difficult challenge for both general practitioners and dermatology consultants. We identified seven major categories of systemic hair loss etiology and present a framework for their clinical evaluation. A methodical approach to hair loss can result in the appropriate treatment plan and provide significant patient satisfaction.

  20. Effects of β-Glucans Ingestion on Alveolar Bone Loss, Intestinal Morphology, Systemic Inflammatory Profile, and Pancreatic β-Cell Function in Rats with Periodontitis and Diabetes

    Science.gov (United States)

    Silva, Viviam de O.; Lobato, Raquel V.; Orlando, Débora R.; Borges, Bruno D.B.; de Sousa, Raimundo V.

    2017-01-01

    This study aimed to evaluate the effects of β-glucan ingestion (Saccharomyces cerevisiae) on the plasmatic levels of tumor necrosis factor-α (TNF-α) and interleukin-10 (IL-10), alveolar bone loss, and pancreatic β-cell function (HOMA-BF) in diabetic rats with periodontal disease (PD). Besides, intestinal morphology was determined by the villus/crypt ratio. A total of 48 Wistar rats weighing 203 ± 18 g were used. Diabetes was induced by the intraperitoneal injection of streptozotocin (80 mg/kg) and periodontal inflammation, by ligature. The design was completely randomized in a factorial scheme 2 × 2 × 2 (diabetic or not, with or without periodontitis, and ingesting β-glucan or not). The animals received β-glucan by gavage for 28 days. Alveolar bone loss was determined by scanning electron microscopy (distance between the cementoenamel junction and alveolar bone crest) and histometric analysis (bone area between tooth roots). β-glucan reduced plasmatic levels of TNF-α in diabetic animals with PD and of IL-10 in animals with PD (p < 0.05). β-glucan reduced bone loss in animals with PD (p < 0.05). In diabetic animals, β-glucan improved β-cell function (p < 0.05). Diabetic animals had a higher villus/crypt ratio (p < 0.05). In conclusion, β-glucan ingestion reduced the systemic inflammatory profile, prevented alveolar bone loss, and improved β-cell function in diabetic animals with PD. PMID:28906456

  1. A Prospective Profile of Visual Field Loss following Stroke: Prevalence, Type, Rehabilitation, and Outcome

    Directory of Open Access Journals (Sweden)

    Fiona J. Rowe

    2013-01-01

    Full Text Available Aims. To profile site of stroke/cerebrovascular accident, type and extent of field loss, treatment options, and outcome. Methods. Prospective multicentre cohort trial. Standardised referral and investigation protocol of visual parameters. Results. 915 patients were recruited with a mean age of 69 years (SD 14. 479 patients (52% had visual field loss. 51 patients (10% had no visual symptoms. Almost half of symptomatic patients (n=226 complained only of visual field loss: almost half (n=226 also had reading difficulty, blurred vision, diplopia, and perceptual difficulties. 31% (n=151 had visual field loss as their only visual impairment: 69% (n=328 had low vision, eye movement deficits, or visual perceptual difficulties. Occipital and parietal lobe strokes most commonly caused visual field loss. Treatment options included visual search training, visual awareness, typoscopes, substitutive prisms, low vision aids, refraction, and occlusive patches. At followup 15 patients (7.5% had full recovery, 78 (39% had improvement, and 104 (52% had no recovery. Two patients (1% had further decline of visual field. Patients with visual field loss had lower quality of life scores than stroke patients without visual impairment. Conclusions. Stroke survivors with visual field loss require assessment to accurately define type and extent of loss, diagnose coexistent visual impairments, and offer targeted treatment.

  2. THE EFFECT OF WEIGHT LOSS ON PLASMA MDA, LIPIDS PROFILE AND APOA AND APOB IN OBESE WOMAN

    Directory of Open Access Journals (Sweden)

    Fatemeh Ramezani

    2010-12-01

    Full Text Available Abstract   INTRODUCTION: Obesity increased reactive oxygen species generation that it result in oxidative injury on lipids profile and lipoproteins that all of which insert atherosclerotic effect. Nutritional intervention by means of a hypocaloric diet could produce protective effects against the redox unbalance.  In this context, the aim of this intervention trial was to estimate the ability of weight loss to improve oxidative stress biomarkers related to lipids peroxidation and lipid profile and apoproteins concentrations of serum in obese women.   METHODS: Thirties eight obese women, 15-45 years old, with body mass index (BMI <30 kg/m2 were recruited. The obese women were assigned to energy-restricted dietary treatments for 12 week. Before and after nutritional intervention and 10% weight reduction, anthropometric measurements were taken and fasting blood was drawn. Plasma levels of (MDA determined with TBAR and triglyceride, total cholesterol and HDL cholesterol. Keywords: MDA, lipid profile, obese woman, Weight loss.

  3. A simple data base for identification of risk profiles

    Energy Technology Data Exchange (ETDEWEB)

    Munganahalli, D.

    1996-12-31

    Sedco Forex is a drilling contractor that operates approximately 80 rigs on land and offshore worldwide. The HSE management system developed by Sedco Forex is an effort to prevent accidents and minimize losses. An integral part of the HSE management system is establishing risk profiles and thereby minimizing risk and reducing loss exposures. Risk profiles are established based on accident reports, potential accident reports and other risk identification reports (RIR) like the Du Pont STOP system. A rig could fill in as many as 30 accident reports, 30 potential accident reports and 500 STOP cards each year. Statistics are important for an HSE management system, since they are indicators of success or failure of HSE systems. It is however difficult to establish risk profiles based on statistical information, unless tools are available at the rig site to aid with the analysis. Risk profiles are then used to identify important areas in the operation that may require specific attention to minimize the loss exposure. Programs to address the loss exposure can then be identified and implemented with either a local or corporate approach. In January 1995, Sedco Forex implemented a uniform HSE Database on all the rigs worldwide. In one year companywide, the HSE database would contain information on approximately 500 accident and potential accident reports, and 10,000 STOP cards. This paper demonstrates the salient features of the database and describes how it has helped in establishing key risk profiles. It also shows a recent example of how risk profiles have been established at the corporate level and used to identify the key contributing factors to hands and finger injuries. Based on this information, a campaign was launched to minimize the frequency of occurrence and associated loss attributed to hands and fingers accidents.

  4. ANALYSIS OF THE HARMONIC LOSSES WITH ARTIFICIAL NEURAL NETWORKS IN UNBALANCED SYSTEM LOSSES USING BALANCED ELECTRIC POWER SYSTEM DATA

    Directory of Open Access Journals (Sweden)

    Aslan İNAN

    2005-01-01

    Full Text Available The losses in the power systems should be low as possible as. Saving energy instead of loses (kWh in power utilities can supply much more energy to the consumers. The lower losses the more energy is saved and thus the power system becomes more economical. In recent years, the increasing number of applications and power ratings of the devices which have nonlinear voltage-current characteristics cause voltage waveform distortion and additional losses. While evaluating losses considering harmonics will provide more contribution to obtain more accurate results. In this study, Artificial Neural Networks (ANN method has been presented to predict the harmonic losses in unbalanced power systems by using the data from balanced power system with nonlinear loads.

  5. Aersol particle losses in sampling systems

    International Nuclear Information System (INIS)

    Fan, B.J.; Wong, F.S.; Ortiz, C.A.; Anand, N.K.; McFarland, A.R.

    1993-01-01

    When aerosols are sampled from stacks and ducts, it is usually necessary to transport them from the point of sampling to a location of collection or analysis. Losses of aerosol particles can occur in the inlet region of the probe, in straight horizontal and vertical tubes and in elbows. For probes in laminary flow, the Saffman lift force can cause substantial losses of particles in a short inlet region. An empirical model has been developed to predict probe inlet losses, which are often on the order of 40% for 10 μm AED particles. A user-friendly PC computer code, DEPOSITION, has been setup to model losses in transport systems. Experiments have been conducted to compare the actual aerosol particle losses in transport systems with those predicted by the DEPOSITION code

  6. The Spanwise Distribution of Losses in Prismatic Turbine Cascade with Non-Uniform Inlet Velocity Profile

    Czech Academy of Sciences Publication Activity Database

    Fürst, J.; Luxa, Martin; Šimurda, David

    2014-01-01

    Roč. 21, č. 2 (2014), s. 135-141 ISSN 1802-1484 R&D Projects: GA ČR(CZ) GAP101/10/1329 Institutional support: RVO:61388998 Keywords : prismatic turbine cascade * losses * velocity profile Subject RIV: BK - Fluid Dynamics http://www.engineeringmechanics.cz/obsahy.html?R=21&C=2

  7. Hires and Losses Tracking System

    Data.gov (United States)

    Social Security Administration — This database contains data about the hires and losses of employees for the Office of Systems-those who join or leave the Office of Systems and those who transfer...

  8. RHIC Beam Loss Monitor System Initial Operation

    International Nuclear Information System (INIS)

    Witkover, R. L.; Michnoff, R. J.; Geller, J. M.

    1999-01-01

    The RHIC Beam Loss Monitor (BLM) System is designed to prevent beam loss quenching of the superconducting magnets, and acquire loss data. Four hundred ion chambers are located around the rings to detect losses. The required 8-decade range in signal current is compressed using an RC pre-integrator ahead of a low current amplifier. A beam abort may be triggered if fast or slow losses exceed programmable threshold levels. A micro-controller based VME module sets references and gains and reads trip status for up to 64 channels. Results obtained with the detectors in the RHIC Sextant Test and the prototype electronics in the AGS-to-RHIC (AtR) transfer line are presented along with the present status of the system

  9. Loss energy states of nonstationary quantum systems

    International Nuclear Information System (INIS)

    Dodonov, V.V.; Man'ko, V.I.

    1978-01-01

    The concept of loss energy states is introduced. The loss energy states of the quantum harmonic damping oscillator are considered in detail. The method of constructing the loss energy states for general multidimensional quadratic nonstationary quantum systems is briefly discussed

  10. Direct transverse load profile determination using the polarization-dependent loss spectral response of a chirped fiber Bragg grating.

    Science.gov (United States)

    Descamps, Frédéric; Bette, Sébastien; Kinet, Damien; Caucheteur, Christophe

    2016-06-01

    The determination of stress profiles created by transverse loads was proved to be important in different domains, such as structural health monitoring and biomechanics, and, more specifically, in the prostheses domain. In this paper, we report an original method to estimate the transverse load profile from the polarization-dependent loss (PDL) spectrum of a chirped fiber Bragg grating (CFBG). This method makes use of the relationship between the integration of the PDL of a CFBG, and the force profile has the advantage of not requiring any iterative method to estimate the transverse load profile. The relationship linking the integration of the PDL and the force profile is demonstrated using an analytical approximation of the transmission spectrum of CFBGs. The validity of this method for the determination of non-uniform load profiles is then shown using a numerical analysis. An experimental demonstration is finally reported using a 48 mm-long CFBG subject to different step transverse load profiles.

  11. RHIC beam loss monitor system design

    International Nuclear Information System (INIS)

    Witkover, R.; Zitvogel, E.; Michnoff, R.

    1997-01-01

    The Beam Loss Monitor (BLM) System is designed to prevent the quenching of RHIC magnets due to beam loss, provide quantitative loss data, and the loss history in the event of a beam abort. The system uses 400 ion chambers of a modified Tevatron design. To satisfy fast (single turn) and slow (100 msec) loss beam criteria and provide sensitivity for studies measurements, a range of over 8 decades is needed. An RC pre-integrator reduces the dynamic range for a low current amplifier. This is digitized for data logging. The output is also applied to an analog multiplier which compensates the energy dependence, extending the range of the abort comparators. High and low pass filters separate the signal to dual comparators with independent programmable trip levels. Up to 64 channels, on 8 VME boards, are controlled by a micro-controller based VME module, decoupling it from the front-end computer (FEC) for real-time operation. Results with the detectors in the RHIC Sextant Test and the electronics in the AGS-to-RHIC (AtR) transfer line will be presented

  12. Alteration of serum lipid profile, SRB1 loss, and impaired Nrf2 activation in CDKL5 disorder.

    Science.gov (United States)

    Pecorelli, Alessandra; Belmonte, Giuseppe; Meloni, Ilaria; Cervellati, Franco; Gardi, Concetta; Sticozzi, Claudia; De Felice, Claudio; Signorini, Cinzia; Cortelazzo, Alessio; Leoncini, Silvia; Ciccoli, Lucia; Renieri, Alessandra; Jay Forman, Henry; Hayek, Joussef; Valacchi, Giuseppe

    2015-09-01

    CDKL5 mutation is associated with an atypical Rett syndrome (RTT) variant. Recently, cholesterol homeostasis perturbation and oxidative-mediated loss of the high-density lipoprotein receptor SRB1 in typical RTT have been suggested. Here, we demonstrate an altered lipid serum profile also in CDKL5 patients with decreased levels of SRB1 and impaired activation of the defensive system Nrf2. In addition, CDKL5 fibroblasts showed an increase in 4-hydroxy-2-nonenal- and nitrotyrosine-SRB1 adducts that lead to its ubiquitination and probable degradation. This study highlights a possible common denominator between two different RTT variants (MECP2 and CDKL5) and a possible common future therapeutic target. Copyright © 2015 Elsevier Inc. All rights reserved.

  13. Time integrated x-ray measurments of the very energetic electron end loss profile in TMX-U

    International Nuclear Information System (INIS)

    Osher, J.E.; Fabyan, J.

    1984-01-01

    The time-integrated 2-D profile of the thick-target bremsstrahlung produced by energetic end loss electrons has been measured during ECRH operation of TMX-U. Sheets of x-ray film and/or arrays of thermoluminescent dosimeters were placed on the outside of the end tank end wall to measure the relative spatial x-ray profile, with locally added filters of Pb to determine the effective mean x-ray energy. The purpose of this simple survey diagnostic was to allow deduction of the gross features of the ECRH region. The electron source functions needed to fit the x-ray data were modeled for various anchor cell radial distributions mapped along magnetic field lines to the elliptical plasma potential control plates or the Al end walls. The data are generally consistent with (1) major ECR heating in the central 25-cm-diam core, (2) a mean ECRH electron loss energy of 420 keV, and (3) an ECRH coupling efficiency to these hot electrons of greater than or equal to 10%

  14. PECULIARITIES OF CONSTRUCTION PROFILES OF SECURITY SYSTEMS OF INFORMATION SYSTEMS

    Directory of Open Access Journals (Sweden)

    Olga V. Lukinova

    2015-01-01

    Full Text Available Examines the specific issues of building functional and technological profiles of the security systems to ensure the safety of information systems in the paradigm of functional standardization; shows a view of the system of protection based on the model of OSE/RM; studied the composition and structure of the concept of "defense mechanism" for the purpose of profiling third instalment correction representation of the system of protection.

  15. System Losses and Assessment Trade Study

    Energy Technology Data Exchange (ETDEWEB)

    David Shropshire; Steve Piet; Nick Soelberg; Robert Cherry; Roger Henry; David Meikrantz; Greg Teske; Eric Shaber; Candido Pereira

    2009-09-01

    This Advanced Fuel Cycle Initiative (AFCI) study has developed new analysis methods to examine old and new technology options toward the goal of improving fuel cycle systems. We have integrated participants and information from AFCI Systems Analysis, Transmutation Fuels, Separations, and Waste Form Campaigns in the Systems Losses and Assessment Trade Study. The initial objectives of this study were to 1) increase understanding of system interdependencies and thereby identify system trade-offs that may yield important insights, 2) define impacts of separations product purity on fuel manufacture and transmutation reactivity, 3) define impacts from transuranic (TRU) losses to waste, 4) identify the interrelationships involved in fuels and separations technology performance, and 5) identify system configuration adjustments with the greatest potential for influencing system losses. While bounding and analyzing this initial problem, we also identified significantly higher-level programmatic drivers with broad implications to the current fuel cycle research charter and the general issue of a DOE complex wide need for a comprehensive and integrated nuclear material management as addressed by the new DOE Order 410.2 titled “Management of Nuclear Materials”. The initial modeling effort developed in this study for a much smaller subset of material (i.e., commercial fuel) and a selected transmutation scheme (i.e., fast reactor recycling) is a necessary first step towards examining a broader set of nuclear material management options, dispositioning strategies and integrated waste management options including potential areas of research leverage. The primary outcome from this initial study has been an enhanced integration among Campaigns and associated insights and analysis methods. Opportunities for improved understanding between the groups abound. The above lanthanide-actinide example highlights the importance of evaluating options via integration across the Campaigns

  16. DATA ACQUISITION FOR SNS BEAM LOSS MONITOR SYSTEM

    International Nuclear Information System (INIS)

    YENG, Y.; GASSNER, D.; HOFF, L.; WITKOVER, R.

    2003-01-01

    The Spallation Neutron Source (SNS) beam loss monitor system uses VME based electronics to measure the radiation produced by lost beam. Beam loss signals from cylindrical argon-filled ion chambers and neutron detectors will be conditioned in analog front-end (AFE) circuitry. These signals will be digitized and further processed in a dedicated VME crate. Fast beam inhibit and low-level, long-term loss warnings will be generated to provide machine protection. The fast loss data will have a bandwidth of 35kHz. While the low level, long-term loss data will have much higher sensitivity. This is further complicated by the 3 decade range of intensity as the Ring accumulates beam. Therefore a bandwidth of 100kHz and dynamic range larger than 21 bits data acquisition system will be required for this purpose. Based on the evaluation of several commercial ADC modules in preliminary design phase, a 24 bits Sigma-Delta data acquisition VME bus card was chosen as the SNS BLM digitizer. An associated vxworks driver and EPICS device support module also have been developed at BNL. Simulating test results showed this system is fully qualified for both fast loss and low-level, long-term loss application. The first prototype including data acquisition hardware setup and EPICS software (running database and OPI clients) will be used in SNS Drift Tube Linac (DTL) system commissioning

  17. Diffraction measurements using the LHC Beam Loss Monitoring System

    Science.gov (United States)

    Kalliokoski, Matti

    2017-03-01

    The Beam Loss Monitoring (BLM) system of the Large Hadron Collider protects the machine from beam induced damage by measuring the absorbed dose rates of beam losses, and by triggering beam dump if the rates increase above the allowed threshold limits. Although the detection time scales are optimized for multi-turn losses, information on fast losses can be recovered from the loss data. In this paper, methods in using the BLM system in diffraction studies are discussed.

  18. The effect of three different doses of tranexamic acid on blood loss after cardiac surgery with mild systemic hypothermia (32 degrees C).

    Science.gov (United States)

    Karski, J M; Dowd, N P; Joiner, R; Carroll, J; Peniston, C; Bailey, K; Glynn, M F; Teasdale, S J; Cheng, D C

    1998-12-01

    Prophylactic administration of tranexamic acid (TA), an antifibrinolytic agent, decreases bleeding after cardiac surgery with systemic hypothermia (25 degrees C to 29 degrees C). Warmer systemic temperatures during cardiopulmonary bypass (CPB) may reduce bleeding and thus alter the requirement for TA. The effect of three different doses of TA on bleeding after cardiac surgery with mild systemic hypothermia (32 degrees C) is evaluated. Double-blind, prospective, randomized study. University hospital. One hundred fifty adult patients undergoing aortocoronary bypass or valvular cardiac surgery. Patients received TA, 50 (n = 50), 100 (n = 50), or 150 (n = 50) mg/kg intravenously before CPB with mild systemic hypothermia. Blood loss through chest drains over 6, 12, and 24 hours after surgery and total hemoglobin loss were measured. Autotransfused blood, transfused banked blood and blood products, and coagulation profiles were measured. Analysis of variance on log-transformed data for blood loss and confidence intervals (CIs) of 0.95 were calculated and transformed to milliliters of blood. No patient was re-explored for bleeding. Blood loss at 6 hours was statistically greater in the 50-mg/kg group compared with the other two groups (p = 0.03; p = 0.02). Total hemoglobin loss was statistically greater in the 50-mg/kg group compared with the 150-mg/kg group (p = 0.04). There was no statistical difference in blood tranfusion rate or coagulation profiles among the three groups. However, preoperative hemoglobin level was statistically lower in the 150-mg/kg group compared with the other two groups (p = 0.01). Of the three doses of TA studied, the most efficacious and cost-effective dose to reduce bleeding after cardiac surgery with mild hypothermic systemic perfusion is 100 mg/kg.

  19. Adaptive Sensing Based on Profiles for Sensor Systems

    Directory of Open Access Journals (Sweden)

    Yoshiteru Ishida

    2009-10-01

    Full Text Available This paper proposes a profile-based sensing framework for adaptive sensor systems based on models that relate possibly heterogeneous sensor data and profiles generated by the models to detect events. With these concepts, three phases for building the sensor systems are extracted from two examples: a combustion control sensor system for an automobile engine, and a sensor system for home security. The three phases are: modeling, profiling, and managing trade-offs. Designing and building a sensor system involves mapping the signals to a model to achieve a given mission.

  20. Effect of ion orbit loss on the structure in the H-mode tokamak edge pedestal profiles of rotation velocity, radial electric field, density, and temperature

    International Nuclear Information System (INIS)

    Stacey, Weston M.

    2013-01-01

    An investigation of the effect of ion orbit loss of thermal ions and the compensating return ion current directly on the radial ion flux flowing in the plasma, and thereby indirectly on the toroidal and poloidal rotation velocity profiles, the radial electric field, density, and temperature profiles, and the interpretation of diffusive and non-diffusive transport coefficients in the plasma edge, is described. Illustrative calculations for a high-confinement H-mode DIII-D [J. Luxon, Nucl. Fusion 42, 614 (2002)] plasma are presented and compared with experimental results. Taking into account, ion orbit loss of thermal ions and the compensating return ion current is found to have a significant effect on the structure of the radial profiles of these quantities in the edge plasma, indicating the necessity of taking ion orbit loss effects into account in interpreting or predicting these quantities

  1. Heat Loss Evaluation of the SMART-ITL Primary System

    International Nuclear Information System (INIS)

    Ryu, Sung Uk; Bae, Hwang; Kim, Dong Eok; Park, Keun Tae; Park, Hyun Sik; Yi, Sung Jae

    2013-01-01

    It is considered that the heat loss rate is one of the critical factors affecting the transient behavior of an integral effect test facility. This paper presents the experimental results of the heat loss rate for the primary system of a SMART-ITL (System-Integrated Modular Advanced ReacTor-Integral Test Loop) facility including the pressurizer (PZR). To evaluate the heat loss rate of the primary system, two different approaches were pursued, i. e., integral and differential approaches. The integral approach is a constant temperature method which controls the core and PZR powers at a desired temperature condition and the differential approach is a natural cooling-down measurement method that lasts for a long period of time. In the present work, the heat losses derived from integral and differential approaches were acquired for the primary system of the SMART-ITL. The results obtained by the two approaches were very similar. In addition, an empirical correlation with respect to the difference between the wall temperature and the ambient temperature was proposed to represent the heat loss characteristics of the SMART-ITL facility. The estimated heat losses could be used to estimate the heat loss during the tests and code simulations

  2. O Star Wind Mass-Loss Rates and Shock Physics from X-ray Line Profiles in Archival XMM RGS Data

    Science.gov (United States)

    Cohen, David

    in order to determine the values of physically meaningful model parameters, and to place confidence limits on them. We have incorporated second-order effects into our models, including resonance scattering. We have also developed tools for modeling the X-ray opacity of the cold, X-ray absorbing wind component, which is a crucial ingredient of the technique we have developed for determining wind mass-loss rates from analyzing the ensemble of emission lines from a given star's X-ray spectrum. In addition to testing state-of-the-art wind shock models and measuring O star mass-loss rates, an important component of our proposed research program is the education of talented undergraduates. Swarthmore undergraduates have made significant contributions to the development of our line profile modeling, the wind opacity modeling, and related research topics such as laboratory astrophysics before going on to PhD programs. Two have been named as finalists for the APS's Apker prize. The research we propose here will involve two undergraduates and will likely lead to honors theses, refereed papers, and the opportunity to present their research results at national and international meetings. By measuring mass-loss rates for all the O stars for which high-resolution X-ray spectra exist and by constraining X-ray production mechanisms, we will address issues important to our understanding of stellar and galactic evolution: including the frequency of core collapse supernovae, the energetics of the Galactic interstellar medium, and the radiation conditions in star formation regions where not only new, solar-type stars form, but also where their planetary systems form and are subject to effects of high-energy emission from nearby stars. In this way, the work we are proposing in this project will make a contribution to NASA's mission to understand cosmic evolution and the conditions for generating and sustaining life in the Universe.

  3. Design of control system for profile gauge

    International Nuclear Information System (INIS)

    Huang Yibin; Zhang Yu'ai

    2013-01-01

    The profile gauge can on-line get the cross section in the steel strip, so it has been widely used in hot continuous rolling production-line. The structure of profile gauge and its distributed hardware structure based on PLC and software design of its control subsystem were introduced. The method of temperature and humidity measurement was analyzed. The time response of X-ray machine control based on RS232 communication was researched. It is proved that the control system meets the requirements of the profile gauge system. (authors)

  4. Tritium loss in molten flibe systems

    Energy Technology Data Exchange (ETDEWEB)

    Longhurst, G.R.; Anderl, R.A. [Idaho National Eng. and Environ. Lab., Idaho Falls, ID (United States); Scott Willms, R. [Los Alamos National Lab., NM (United States)

    2000-04-01

    An emerging issue relative to beryllium technology in fusion involves tritium interactions with molten beryllium-bearing salts. Innovative designs for fusion reactors, both magnetic and inertially confined, feature the molten salt mixture 2LiF.BeF{sub 2}, commonly called Flibe, as a tritium breeder and coolant. Tritium is bred in the Flibe as neutrons from the plasma are absorbed by Li atoms, which then transmute to tritium and helium. Transmutation of tritium from Be also occurs. Among the issues to be resolved for such coolant systems is the potential loss of tritium from the Flibe coolant to the walls of the system, particularly through heat exchanger tubes, and from there into secondary coolants or working fluids and the environment. Effectively removing tritium from Flibe in clean-up units is also important. In quiescent or low Reynolds number flow, tritium movement through Flibe is governed by diffusion. For Flibe in turbulent flow, as in heat exchanger tubes, transport is by turbulent mixing, and the same flow conditions and structural design features that maximize heat transfer to the heat exchanger walls will enhance the transport of tritium to those same surfaces. Analyses have been performed to estimate the fractional loss of tritium through heat exchanger tubes and release rates from Flibe droplets in vacuum disengagers in molten Flibe systems. The calculations suggest unacceptably large losses of tritium through heat exchanger tubes. The gravity of the implications of these estimates calls for experimental verification to determine if tritium losses through molten Flibe heat exchangers or other Flibe systems can really be so high and whether vacuum disengagers will really work. There is also a need for better information on evolution of tritium from Flibe droplets in a vacuum. Several experiments are presently being planned to address these issues and are discussed. These include experiments to induce tritium in Flibe using spontaneous fission neutrons

  5. Tritium loss in molten flibe systems

    International Nuclear Information System (INIS)

    Longhurst, G.R.; Anderl, R.A.; Scott Willms, R.

    2000-01-01

    An emerging issue relative to beryllium technology in fusion involves tritium interactions with molten beryllium-bearing salts. Innovative designs for fusion reactors, both magnetic and inertially confined, feature the molten salt mixture 2LiF.BeF 2 , commonly called Flibe, as a tritium breeder and coolant. Tritium is bred in the Flibe as neutrons from the plasma are absorbed by Li atoms, which then transmute to tritium and helium. Transmutation of tritium from Be also occurs. Among the issues to be resolved for such coolant systems is the potential loss of tritium from the Flibe coolant to the walls of the system, particularly through heat exchanger tubes, and from there into secondary coolants or working fluids and the environment. Effectively removing tritium from Flibe in clean-up units is also important. In quiescent or low Reynolds number flow, tritium movement through Flibe is governed by diffusion. For Flibe in turbulent flow, as in heat exchanger tubes, transport is by turbulent mixing, and the same flow conditions and structural design features that maximize heat transfer to the heat exchanger walls will enhance the transport of tritium to those same surfaces. Analyses have been performed to estimate the fractional loss of tritium through heat exchanger tubes and release rates from Flibe droplets in vacuum disengagers in molten Flibe systems. The calculations suggest unacceptably large losses of tritium through heat exchanger tubes. The gravity of the implications of these estimates calls for experimental verification to determine if tritium losses through molten Flibe heat exchangers or other Flibe systems can really be so high and whether vacuum disengagers will really work. There is also a need for better information on evolution of tritium from Flibe droplets in a vacuum. Several experiments are presently being planned to address these issues and are discussed. These include experiments to induce tritium in Flibe using spontaneous fission neutrons

  6. Development of a Millimeter-Wave Beam Position and Profile Monitor for Transmission Efficiency Improvement in an ECRH System

    Directory of Open Access Journals (Sweden)

    Shimozuma T.

    2015-01-01

    Full Text Available In a high power Electron Cyclotron Resonance Heating (ECRH system, a long-distance and low-loss transmission system is required to realize effective heating of nuclear fusion-relevant plasmas. A millimeter-wave beam position and profile monitor, which can be used in a high-power, evacuated, and cooled transmission line, is proposed, designed, manufactured, and tested. The beam monitor consists of a reflector, Peltier-device array and a heat-sink. It was tested using simulated electric heater power or gyrotron output power. The data obtained from the monitor were well agreed with the heat source position and profile. The methods of data analysis and mode-content analysis of a propagating millimeter-wave in the corrugated wave-guide are proposed.

  7. AIP Diffraction measurements using the LHC Beam Loss Monitoring System

    CERN Document Server

    Kalliokoski, Matti

    2017-01-01

    The Beam Loss Monitoring (BLM) system of the Large Hadron Collider protects the machine from beam induced damage by measuring the absorbed dose rates of beam losses, and by triggering beam dump if the rates increase above the allowed threshold limits. Although the detection time scales are optimized for multi-turn losses, information on fast losses can be recovered from the loss data. In this paper, methods in using the BLM system in di ff raction studies are discussed.

  8. Soil Temperature and Moisture Profile (STAMP) System Handbook

    Energy Technology Data Exchange (ETDEWEB)

    Cook, David R. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-11-01

    The soil temperature and moisture profile system (STAMP) provides vertical profiles of soil temperature, soil water content (soil-type specific and loam type), plant water availability, soil conductivity, and real dielectric permittivity as a function of depth below the ground surface at half-hourly intervals, and precipitation at one-minute intervals. The profiles are measured directly by in situ probes at all extended facilities of the SGP climate research site. The profiles are derived from measurements of soil energy conductivity. Atmospheric scientists use the data in climate models to determine boundary conditions and to estimate the surface energy flux. The data are also useful to hydrologists, soil scientists, and agricultural scientists for determining the state of the soil. The STAMP system replaced the SWATS system in early 2016.

  9. Reliability of Beam Loss Monitors System for the Large Hadron Collider

    CERN Document Server

    Guaglio, Gianluca; Santoni, C

    2004-01-01

    The employment of superconducting magnets, in the high energies colliders, opens challenging failure scenarios and brings new criticalities for the whole system protection. For the LHC beam loss protection system, the failure rate and the availability requirements have been evaluated using the Safety Integrity Level (SIL) approach. A downtime cost evaluation is used as input for the SIL approach. The most critical systems, which contribute to the final SIL value, are the dump system, the interlock system, the beam loss monitors system and the energy monitor system. The Beam Loss Monitors System (BLMS) is critical for short and intense particles losses, while at medium and higher loss time it is assisted by other systems, such as the quench protection system and the cryogenic system. For BLMS, hardware and software have been evaluated in detail. The reliability input figures have been collected using historical data from the SPS, using temperature and radiation damage experimental data as well as using standar...

  10. Reliability of Beam Loss Monitor Systems for the Large Hadron Collider

    CERN Document Server

    Guaglio, Gianluca; Santoni, C

    2005-01-01

    The increase of beam energy and beam intensity, together with the use of super conducting magnets, opens new failure scenarios and brings new criticalities for the whole accelerator protection system. For the LHC beam loss protection system, the failure rate and the availability requirements have been evaluated using the Safety Integrity Level (SIL) approach. A downtime cost evaluation is used as input for the SIL approach. The most critical systems, which contribute to the final SIL value, are the dump system, the interlock system, the beam loss monitors system, and the energy monitor system. The Beam Loss Monitors System (BLMS) is critical for short and intense particles losses at 7 TeV and assisted by the Fast Beam Current Decay Monitors at 450 GeV. At medium and higher loss time it is assisted by other systems, such as the quench protection system and the cryogenic system. For BLMS, hardware and software have been evaluated in detail. The reliability input figures have been collected using historical data...

  11. Preservation of beam loss induced quenches, beam lifetime and beam loss measurements with the HERA-p beam-loss-monitor system

    International Nuclear Information System (INIS)

    Wittenburg, K.

    1994-01-01

    The beam-loss-monitors (BLMs) in the HERA-Proton-ring (HERAp) must fulfil the following requirements: They have to measure losses sensitive and fast enough to prevent the superconducting magnets from beam loss induced quenching; the dynamic range of the monitors must exceed several decades in order to measure losses during beam lifetimes of hundreds of hours as well as the much stronger losses that may quench superconducting magnets; they have to be insensitive to the synchrotron radiation of the adjacent electron-ring (HERAe); and their radiation hardness must allow a monitor-lifetime of a few years of HERA operation. These requirements are well satisfied by the HERAp-BLM-System. (orig.)

  12. Loss of variation of state detected in soybean metabolic and human myelomonocytic leukaemia cell transcriptional networks under external stimuli

    KAUST Repository

    Sakata, Katsumi

    2016-10-24

    Soybean (Glycine max) is sensitive to flooding stress, and flood damage at the seedling stage is a barrier to growth. We constructed two mathematical models of the soybean metabolic network, a control model and a flooded model, from metabolic profiles in soybean plants. We simulated the metabolic profiles with perturbations before and after the flooding stimulus using the two models. We measured the variation of state that the system could maintain from a state–space description of the simulated profiles. The results showed a loss of variation of state during the flooding response in the soybean plants. Loss of variation of state was also observed in a human myelomonocytic leukaemia cell transcriptional network in response to a phorbol-ester stimulus. Thus, we detected a loss of variation of state under external stimuli in two biological systems, regardless of the regulation and stimulus types. Our results suggest that a loss of robustness may occur concurrently with the loss of variation of state in biological systems. We describe the possible applications of the quantity of variation of state in plant genetic engineering and cell biology. Finally, we present a hypothetical “external stimulus-induced information loss” model of biological systems.

  13. Loss of variation of state detected in soybean metabolic and human myelomonocytic leukaemia cell transcriptional networks under external stimuli

    KAUST Repository

    Sakata, Katsumi; Saito, Toshiyuki; Ohyanagi, Hajime; Okumura, Jun; Ishige, Kentaro; Suzuki, Harukazu; Nakamura, Takuji; Komatsu, Setsuko

    2016-01-01

    Soybean (Glycine max) is sensitive to flooding stress, and flood damage at the seedling stage is a barrier to growth. We constructed two mathematical models of the soybean metabolic network, a control model and a flooded model, from metabolic profiles in soybean plants. We simulated the metabolic profiles with perturbations before and after the flooding stimulus using the two models. We measured the variation of state that the system could maintain from a state–space description of the simulated profiles. The results showed a loss of variation of state during the flooding response in the soybean plants. Loss of variation of state was also observed in a human myelomonocytic leukaemia cell transcriptional network in response to a phorbol-ester stimulus. Thus, we detected a loss of variation of state under external stimuli in two biological systems, regardless of the regulation and stimulus types. Our results suggest that a loss of robustness may occur concurrently with the loss of variation of state in biological systems. We describe the possible applications of the quantity of variation of state in plant genetic engineering and cell biology. Finally, we present a hypothetical “external stimulus-induced information loss” model of biological systems.

  14. The LCLS Undulator Beam Loss Monitor Readout System

    Energy Technology Data Exchange (ETDEWEB)

    Dusatko, John; Browne, M.; Fisher, A.S.; Kotturi, D.; Norum, S.; Olsen, J.; /SLAC

    2012-07-23

    The LCLS Undulator Beam Loss Monitor System is required to detect any loss radiation seen by the FEL undulators. The undulator segments consist of permanent magnets which are very sensitive to radiation damage. The operational goal is to keep demagnetization below 0.01% over the life of the LCLS. The BLM system is designed to help achieve this goal by detecting any loss radiation and indicating a fault condition if the radiation level exceeds a certain threshold. Upon reception of this fault signal, the LCLS Machine Protection System takes appropriate action by either halting or rate limiting the beam. The BLM detector consists of a PMT coupled to a Cherenkov radiator located near the upstream end of each undulator segment. There are 33 BLMs in the system, one per segment. The detectors are read out by a dedicated system that is integrated directly into the LCLS MPS. The BLM readout system provides monitoring of radiation levels, computation of integrated doses, detection of radiation excursions beyond set thresholds, fault reporting and control of BLM system functions. This paper describes the design, construction and operational performance of the BLM readout system.

  15. The Beam Loss Detection System of the LHC Ring

    CERN Document Server

    Gschwendtner, E; Ferioli, G; Friesenbichler, W; Kain, V

    2002-01-01

    At the Large Hadron Collider (LHC) a beam loss system will be installed in the arc, dispersion suppressor and the straight regions for a continuous surveillance of particle losses. These beam particles deposit their energy partially in the super-conducting coils leading to temperature increase, possible magnet quenches and damages. The primary and secondary halo of the beam is absorbed by the collimation system. The tertiary halo will be lost at aperture limits in the ring. Its loss distribution along the magnets has been studies. At the positions, where most of the beam losses are expected, simulations of the particle fluences outside the cryostat and induced by lost protons at the aperture have been performed with the Monte Carlo Code Geant 3.2.1. This allows determining the most suitable positions of the detectors, the needed number of monitors and the impact on the dynamic range of the detectors. The design of the beam loss monitor system is presented that meet the required sensitivity, dynamic range and ...

  16. The AGS Booster beam loss monitor system

    International Nuclear Information System (INIS)

    Beadle, E.R.; Bennett, G.W.; Witkover, R.L.

    1991-01-01

    A beam loss monitor system has been developed for the Brookhaven National Laboratory Booster accelerator, and is designed for use with intensities of up to 1.5 x 10 13 protons and carbon to gold ions at 50-3 x 10 9 ions per pulse. This system is a significant advance over the present AGS system by improving the sensitivity, dynamic range, and data acquisition. In addition to the large dynamic range achievable, it is adaptively shifted when high losses are detected. The system uses up to 80 argon filled ion chambers as detectors, as well as newly designed electronics for processing and digitizing detector outputs. The hardware simultaneously integrates each detector output, interfaces to the beam interrupt systems, and digitizes all 80 channels to 21 bits at 170 KHz. This paper discuses the design, construction, and operation of the system. 4 refs., 2 figs

  17. Long radiation detector system for beam loss monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Balsamo, J.; Fewell, N.M.; Klein, J.D.; Witkover, R.L.

    1977-01-01

    The Long Radiation Monitor (LRM) system installed at the 200 MeV linac at Brookhaven National Laboratory is described. This system allows observation of both the spatial and temporal character of the losses in the linac and its transport lines. An array of large diameter gas filled coaxial cables are used as extended ion chambers to detect the losses. The output signals are available as a histogram, video waveforms, and numerical data via the computer. A fast beam interrupt is also provided. The detector characteristics and details of the processing electronics are presented. Results of studies of longitudinal, steering and focusing losses are described.

  18. Long radiation detector system for beam loss monitoring

    International Nuclear Information System (INIS)

    Balsamo, J.; Fewell, N.M.; Klein, J.D.; Witkover, R.L.

    1977-01-01

    The Long Radiation Monitor (LRM) system installed at the 200 MeV linac at Brookhaven National Laboratory is described. This system allows observation of both the spatial and temporal character of the losses in the linac and its transport lines. An array of large diameter gas filled coaxial cables are used as extended ion chambers to detect the losses. The output signals are available as a histogram, video waveforms, and numerical data via the computer. A fast beam interrupt is also provided. The detector characteristics and details of the processing electronics are presented. Results of studies of longitudinal, steering and focusing losses are described

  19. Significance of losses in water distribution systems in India.

    Science.gov (United States)

    Raman, V

    1983-01-01

    Effective management of water supply systems consists in supplying adequate quantities of clean water to the population. Detailed pilot studies of water distribution systems were carried out in 9 cities in India during 1971-81 to establish the feasibility of a programme of assessment, detection, and control of water losses from supply systems. A cost-benefit analysis was carried out. Water losses from mains and service pipes in the areas studied amounted to 20-35% of the total flow in the system. At a conservative estimate, the national loss of processed water through leaks in the water distribution systems amounts to 10(12) litres per year, which is equivalent to 500 million rupees.It is possible to bring down the water losses in the pipe mains to 3-5% of the total flow, and the cost incurred on the control programme can be recovered in 6-18 months. Appropriate conservation measures will help in achieving the goals of the International Water Supply and Sanitation Decade to provide clean water for all.

  20. Reliability of Beam Loss Monitors System for the Large Hadron Collider

    Science.gov (United States)

    Guaglio, G.; Dehning, B.; Santoni, C.

    2004-11-01

    The employment of superconducting magnets in high energy colliders opens challenging failure scenarios and brings new criticalities for the whole system protection. For the LHC beam loss protection system, the failure rate and the availability requirements have been evaluated using the Safety Integrity Level (SIL) approach. A downtime cost evaluation is used as input for the SIL approach. The most critical systems, which contribute to the final SIL value, are the dump system, the interlock system, the beam loss monitors system and the energy monitor system. The Beam Loss Monitors System (BLMS) is critical for short and intense particle losses, while at medium and higher loss time it is assisted by other systems, such as the quench protection system and the cryogenic system. For BLMS, hardware and software have been evaluated in detail. The reliability input figures have been collected using historical data from the SPS, using temperature and radiation damage experimental data as well as using standard databases. All the data have been processed by reliability software (Isograph). The analysis ranges from the components data to the system configuration.

  1. Reliability of Beam Loss Monitors System for the Large Hadron Collider

    International Nuclear Information System (INIS)

    Guaglio, G.; Dehning, B.; Santoni, C.

    2004-01-01

    The employment of superconducting magnets in high energy colliders opens challenging failure scenarios and brings new criticalities for the whole system protection. For the LHC beam loss protection system, the failure rate and the availability requirements have been evaluated using the Safety Integrity Level (SIL) approach. A downtime cost evaluation is used as input for the SIL approach. The most critical systems, which contribute to the final SIL value, are the dump system, the interlock system, the beam loss monitors system and the energy monitor system. The Beam Loss Monitors System (BLMS) is critical for short and intense particle losses, while at medium and higher loss time it is assisted by other systems, such as the quench protection system and the cryogenic system. For BLMS, hardware and software have been evaluated in detail. The reliability input figures have been collected using historical data from the SPS, using temperature and radiation damage experimental data as well as using standard databases. All the data have been processed by reliability software (Isograph). The analysis ranges from the components data to the system configuration

  2. Data Acquisition System for Electron Energy Loss Coincident Spectrometers

    International Nuclear Information System (INIS)

    Zhang Chi; Yu Xiaoqi; Yang Tao

    2005-01-01

    A Data Acquisition System (DAQ) for electron energy loss coincident spectrometers (EELCS) has been developed. The system is composed of a Multiplex Time-Digital Converter (TDC) that measures the flying time of positive and negative ions and a one-dimension position-sensitive detector that records the energy loss of scattering electrons. The experimental data are buffered in a first-in-first-out (FIFO) memory module, then transferred from the FIFO memory to PC by the USB interface. The DAQ system can record the flying time of several ions in one collision, and allows of different data collection modes. The system has been demonstrated at the Electron Energy Loss Coincident Spectrometers at the Laboratory of Atomic and Molecular Physics, USTC. A detail description of the whole system is given and experimental results shown

  3. Calorimetric Measuring Systems for Characterizing High Frequency Power Losses in Power Electronic Components and Systems

    DEFF Research Database (Denmark)

    Blaabjerg, Frede; Pedersen, John Kim; Ritchie, Andrew Ewen

    2002-01-01

    High frequency power losses in power electronic components and systems are very difficult to measure. The same applies to the efficiency of high-efficiency systems and components. An important method to measure losses with high accuracy is the calorimetric measuring systems. This paper describes...... to calibrate such systems are proposed and different applications of the system are given. Two practical examples end the description of the research. It is concluded that such systems have a relative long time-constant but they are accurate and useful for precise power loss measurement....

  4. DGA-based VAR rescheduling for transmission loss reduction

    Energy Technology Data Exchange (ETDEWEB)

    Mishra, S. [Indian Inst. of Technology, Delhi (India); Taylor, G.A. [Brunel Univ., London (United Kingdom). Brunel Inst. of Power Systems; Reddy, J.B.V. [Government of India, New Delhi (India). Dept. of Science and Technology; Naeem, M.H. [Multimedia Univ. (Malaysia). Faculty of Engineering

    2009-07-01

    Power losses in power transmission lines can be minimized by adjusting transformer taps and switchable VAR sources. Optimal power flow (OPF) is a static, nonlinear, multi-objective optimization challenge in which the optimal settings of control variables must be determined for minimizing the cost of generation, emissions, transmission losses and voltage and power flow deviations. OPF is important in power system operation because a small savings per hour can mean a large annual savings. This paper presented a method to reduce transmission power losses using a Differential Genetic Algorithm (DGA) for VAR rescheduling. The New England 39-bus power system was used as a test case. Power losses were minimized by changing the tap settings of various transformers and by varying the injected reactive power. The paper showed that certain buses in the system can improve the voltage profile and reduce transmission losses through reactive power injections from capacitor banks. In this study, minimum reactive power output of generators was maintained at zero to ensure that the generators did not draw reactive power. The DGA was shown to produce better results than the Conventional Genetic Algorithm in terms of power loss minimization. 12 refs., 1 tab., 2 figs.

  5. Losses, inefficiencies and waste in the global food system.

    Science.gov (United States)

    Alexander, Peter; Brown, Calum; Arneth, Almut; Finnigan, John; Moran, Dominic; Rounsevell, Mark D A

    2017-05-01

    Losses at every stage in the food system influence the extent to which nutritional requirements of a growing global population can be sustainably met. Inefficiencies and losses in agricultural production and consumer behaviour all play a role. This paper aims to understand better the magnitude of different losses and to provide insights into how these influence overall food system efficiency. We take a systems view from primary production of agricultural biomass through to human food requirements and consumption. Quantities and losses over ten stages are calculated and compared in terms of dry mass, wet mass, protein and energy. The comparison reveals significant differences between these measurements, and the potential for wet mass figures used in previous studies to be misleading. The results suggest that due to cumulative losses, the proportion of global agricultural dry biomass consumed as food is just 6% (9.0% for energy and 7.6% for protein), and 24.8% of harvest biomass (31.9% for energy and 27.8% for protein). The highest rates of loss are associated with livestock production, although the largest absolute losses of biomass occur prior to harvest. Losses of harvested crops were also found to be substantial, with 44.0% of crop dry matter (36.9% of energy and 50.1% of protein) lost prior to human consumption. If human over-consumption, defined as food consumption in excess of nutritional requirements, is included as an additional inefficiency, 48.4% of harvested crops were found to be lost (53.2% of energy and 42.3% of protein). Over-eating was found to be at least as large a contributor to food system losses as consumer food waste. The findings suggest that influencing consumer behaviour, e.g. to eat less animal products, or to reduce per capita consumption closer to nutrient requirements, offer substantial potential to improve food security for the rising global population in a sustainable manner.

  6. DISTRIBUTION NETWORK RECONFIGURATION FOR POWER LOSS MINIMIZATION AND VOLTAGE PROFILE ENHANCEMENT USING ANT LION ALGORITHM

    Directory of Open Access Journals (Sweden)

    Maryam Shokouhi

    2017-06-01

    Full Text Available Distribution networks are designed as a ring and operated as a radial form. Therefore, the reconfiguration is a simple and cost-effective way to use existing facilities without the need for any new equipment in distribution networks to achieve various objectives such as: power loss reduction, feeder overload reduction, load balancing, voltage profile improvement, reducing the number of switching considering constraints that ultimately result in the power loss reduction. In this paper, a new method based on the Ant Lion algorithm (a modern meta-heuristic algorithm is provided for the reconfiguration of distribution networks. Considering the extension of the distribution networks and complexity of their communications networks, and the various parameters, using smart techniques is inevitable. The proposed approach is tested on the IEEE 33 & 69-bus radial standard distribution networks. The Evaluation of results in MATLAB software shows the effectiveness of the Ant Lion algorithm in the distribution network reconfiguration.

  7. Real-time beam profile imaging system for actinotherapy accelerator

    International Nuclear Information System (INIS)

    Lin Yong; Wang Jingjin; Song Zheng; Zheng Putang; Wang Jianguo

    2003-01-01

    This paper describes a real-time beam profile imaging system for actinotheraphy accelerator. With the flash X-ray imager and the technique of digital image processing, a real-time 3-dimension dosage image is created from the intensity profile of the accelerator beam in real time. This system helps to obtain all the physical characters of the beam in any section plane, such as FWHM, penumbra, peak value, symmetry and homogeneity. This system has been used to acquire a 3-dimension dosage distribution of dynamic wedge modulator and the transient process of beam dosage. The system configure and the tested beam profile images are also presented

  8. Reliability of Beam Loss Monitor Systems for the Large Hadron Collider

    International Nuclear Information System (INIS)

    Guaglio, G.; Dehning, B.; Santoni, C.

    2005-01-01

    The increase of beam energy and beam intensity, together with the use of super conducting magnets, opens new failure scenarios and brings new criticalities for the whole accelerator protection system. For the LHC beam loss protection system, the failure rate and the availability requirements have been evaluated using the Safety Integrity Level (SIL) approach. A downtime cost evaluation is used as input for the SIL approach. The most critical systems, which contribute to the final SIL value, are the dump system, the interlock system, the beam loss monitors system, and the energy monitor system. The Beam Loss Monitors System (BLMS) is critical for short and intense particles losses at 7 TeV and assisted by the Fast Beam Current Decay Monitors at 450 GeV. At medium and higher loss time it is assisted by other systems, such as the quench protection system and the cryogenic system. For BLMS, hardware and software have been evaluated in detail. The reliability input figures have been collected using historical data from the SPS, using temperature and radiation damage experimental data as well as using standard databases. All the data has been processed by reliability software (Isograph). The analysis spaces from the components data to the system configuration

  9. Reliability of Beam Loss Monitor Systems for the Large Hadron Collider

    Science.gov (United States)

    Guaglio, G.; Dehning, B.; Santoni, C.

    2005-06-01

    The increase of beam energy and beam intensity, together with the use of super conducting magnets, opens new failure scenarios and brings new criticalities for the whole accelerator protection system. For the LHC beam loss protection system, the failure rate and the availability requirements have been evaluated using the Safety Integrity Level (SIL) approach. A downtime cost evaluation is used as input for the SIL approach. The most critical systems, which contribute to the final SIL value, are the dump system, the interlock system, the beam loss monitors system, and the energy monitor system. The Beam Loss Monitors System (BLMS) is critical for short and intense particles losses at 7 TeV and assisted by the Fast Beam Current Decay Monitors at 450 GeV. At medium and higher loss time it is assisted by other systems, such as the quench protection system and the cryogenic system. For BLMS, hardware and software have been evaluated in detail. The reliability input figures have been collected using historical data from the SPS, using temperature and radiation damage experimental data as well as using standard databases. All the data has been processed by reliability software (Isograph). The analysis spaces from the components data to the system configuration.

  10. Impact of weight loss on markers of systemic inflammation in obese ...

    African Journals Online (AJOL)

    Background: Weight loss studies were conducted in children without asthma have demonstrated a reduction in systemic inflammation. However, the impact of weight loss in the obese paediatric population with asthma has not been investigated. Objective: To measure the effects of weight loss on markers of systemic ...

  11. Video profile monitor diagnostic system for GTA

    International Nuclear Information System (INIS)

    Sandoval, D.P.; Garcia, R.C.; Gilpatrick, J.D.; Johnson, K.F.; Shinas, M.A.; Wright, R.; Yuan, V.; Zander, M.E.

    1992-01-01

    This paper describes a video diagnostic system used to measure the beam profile and position of the Ground Test Accelerator 2.5-MeV H - ion beam as it exits the intermediate matching section. Inelastic collisions between H-ions and residual nitrogen to fluoresce. The resulting light is captured through transport optics by an intensified CCD camera and is digitized. Real-time beam-profile images are displayed and stored for detailed analysis. Analyzed data showing resolutions for both position and profile measurements will also be presented

  12. The beam loss monitoring system for HLS storage ring

    CERN Document Server

    Li Yu Xiong; Li Wei; Li Jue Xin; Liu Zu Ping; Shao Bei Bei

    2001-01-01

    A beam loss monitoring system has been established at HLS. This paper gives its principle and scientific grounds. Study on the ring's TBA structure and utilization of Monte-Carlo calculation to the shower electrons is important in its design. The system composition and performance are also introduced. The detector BLMs, data acquisition devices and host PC are linked via CAN bus. This system is helpful to analyze beam loss distribution and regulate the machine operation parameters.

  13. Methods Research about Accuracy Loss Tracing of Dynamic Measurement System Based on WNN

    International Nuclear Information System (INIS)

    Lin, S-W; Fei, Y T; Jiang, M L; Tsai, C-Y; Cheng Hsinyu

    2006-01-01

    The paper presents a method of achieving accuracy loss of the dynamic measurement system according to change of errors on different period of the system. WNN, used to trace the accuracy loss of dynamic measurement system, traces the total precision loss during a certain period to every part of the system, and the accuracy loss of every part can be get, so retaining the accuracy and optimum design of the system is possible. Take tracing the accuracy loss of a simulated system for an example to testify the method

  14. Commissioning and operational scenarios of the LHC beam loss monitor system

    International Nuclear Information System (INIS)

    Holzer, E.B.

    2007-01-01

    One of the most critical elements for the protection of CERN's Large Hadron Collider (LHC) is its beam loss monitoring (BLM) system. It must prevent quenches in the super conducting magnets and damage of machine components due to beam losses. The contribution will discuss the commissioning procedures of the BLM system and envisaged operational scenarios. About 4000 monitors will be installed around the ring. When the loss rate exceeds a predefined threshold value, a beam abort is requested. Magnet quench and damage levels vary as a function of beam energy and loss duration. Consequently, the beam abort threshold values vary accordingly. By measuring the loss pattern, the BLM system helps to identify the loss mechanism. Furthermore, it will be an important tool for commissioning, machine setup and studies. Special monitors will be used for the setup and control of the collimators. (author)

  15. Significance of losses in water distribution systems in India

    OpenAIRE

    Raman, V.

    1983-01-01

    Effective management of water supply systems consists in supplying adequate quantities of clean water to the population. Detailed pilot studies of water distribution systems were carried out in 9 cities in India during 1971-81 to establish the feasibility of a programme of assessment, detection, and control of water losses from supply systems. A cost-benefit analysis was carried out. Water losses from mains and service pipes in the areas studied amounted to 20-35% of the total flow in the sys...

  16. Salivary Cortisol Profiles of Children with Hearing Loss

    Science.gov (United States)

    Bess, Fred H.; Gustafson, Samantha J.; Corbett, Blythe A.; Lambert, E. Warren; Camarata, Stephen M.; Hornsby, Benjamin W. Y.

    2016-01-01

    Objectives: It has long been speculated that effortful listening places children with hearing loss at risk for fatigue. School-age children with hearing loss experiencing cumulative stress and listening fatigue on a daily basis might undergo dysregulation of hypothalamic-pituitary-adrenal (HPA) axis activity resulting in elevated or flattened…

  17. Sampled-Data Consensus of Linear Multi-agent Systems With Packet Losses.

    Science.gov (United States)

    Zhang, Wenbing; Tang, Yang; Huang, Tingwen; Kurths, Jurgen

    In this paper, the consensus problem is studied for a class of multi-agent systems with sampled data and packet losses, where random and deterministic packet losses are considered, respectively. For random packet losses, a Bernoulli-distributed white sequence is used to describe packet dropouts among agents in a stochastic way. For deterministic packet losses, a switched system with stable and unstable subsystems is employed to model packet dropouts in a deterministic way. The purpose of this paper is to derive consensus criteria, such that linear multi-agent systems with sampled-data and packet losses can reach consensus. By means of the Lyapunov function approach and the decomposition method, the design problem of a distributed controller is solved in terms of convex optimization. The interplay among the allowable bound of the sampling interval, the probability of random packet losses, and the rate of deterministic packet losses are explicitly derived to characterize consensus conditions. The obtained criteria are closely related to the maximum eigenvalue of the Laplacian matrix versus the second minimum eigenvalue of the Laplacian matrix, which reveals the intrinsic effect of communication topologies on consensus performance. Finally, simulations are given to show the effectiveness of the proposed results.In this paper, the consensus problem is studied for a class of multi-agent systems with sampled data and packet losses, where random and deterministic packet losses are considered, respectively. For random packet losses, a Bernoulli-distributed white sequence is used to describe packet dropouts among agents in a stochastic way. For deterministic packet losses, a switched system with stable and unstable subsystems is employed to model packet dropouts in a deterministic way. The purpose of this paper is to derive consensus criteria, such that linear multi-agent systems with sampled-data and packet losses can reach consensus. By means of the Lyapunov function

  18. A Versatile Beam Loss Monitoring System for CLIC

    CERN Document Server

    Kastriotou, Maria; Farabolini, Wilfrid; Holzer, Eva Barbara; Nebot Del Busto, Eduardo; Tecker, Frank; Welsch, Carsten

    2016-01-01

    The design of a potential CLIC beam loss monitoring (BLM) system presents multiple challenges. To successfully cover the 48 km of beamline, ionisation chambers and optical fibre BLMs are under investigation. The former fulfils all CLIC requirements but would need more than 40000 monitors to protect the whole facility. For the latter, the capability of reconstructing the original loss position with a multi-bunch beam pulse and multiple loss locations still needs to be quantified. Two main sources of background for beam loss measurements are identified for CLIC. The two-beam accelerator scheme introduces so-called crosstalk, i.e. detection of losses originating in one beam line by the monitors protecting the other. Moreover, electrons emitted from the inner surface of RF cavities and boosted by the high RF gradients may produce signals in neighbouring BLMs, limiting their ability to detect real beam losses. This contribution presents the results of dedicated experiments performed in the CLIC Test Facility to qu...

  19. Real-Time System Supervision for the LHC Beam Loss Monitoring System at CERN

    CERN Document Server

    Zamantzas, C; Effinger, E; Emery, J; Jackson, S

    2014-01-01

    The strategy for machine protection and quench prevention of the Large Hadron Collider (LHC) at the European Organisation for Nuclear Research (CERN) is mainly based on the Beam Loss Monitoring (BLM) system. The LHC BLM system is one of the most complex and large instrumentation systems deployed in the LHC. In addition to protecting the collider, the system also needs to provide a means of diagnosing machine faults and deliver feedback of the losses to the control room as well as to several systems for their setup and analysis. In order to augment the dependability of the system several layers of supervision has been implemented internally and externally to the system. This paper describes the different methods employed to achieve the expected availability and system fault detection.

  20. Video profile monitor diagnostic system for GTA

    International Nuclear Information System (INIS)

    Sandovil, D.P.; Garcia, R.C.; Gilpatrick, J.D.; Johnson, K.F.; Shinas, M.A.; Wright, R.; Yuan, V.; Zander, M.E.

    1992-01-01

    This paper describes a video diagnostic system used to measure the beam profile and position of the Ground Test Accelerator 2.5 MeV H - ion beam as it exits the intermediate matching section. Inelastic collisions between H - ions and residual nitrogen in the vacuum chamber cause the nitrogen to fluoresce. The resulting light is captured through transport optics by an intensified CCD camera and is digitized. Real-time beam profile images are displayed and stored for detailed analysis. Analyzed data showing resolutions for both position and profile measurements will also be presented. (Author) 5 refs., 7 figs

  1. Discrete Model Reference Adaptive Control System for Automatic Profiling Machine

    Directory of Open Access Journals (Sweden)

    Peng Song

    2012-01-01

    Full Text Available Automatic profiling machine is a movement system that has a high degree of parameter variation and high frequency of transient process, and it requires an accurate control in time. In this paper, the discrete model reference adaptive control system of automatic profiling machine is discussed. Firstly, the model of automatic profiling machine is presented according to the parameters of DC motor. Then the design of the discrete model reference adaptive control is proposed, and the control rules are proven. The results of simulation show that adaptive control system has favorable dynamic performances.

  2. An analysis of power sector system losses in Bangladesh and Pakistan

    International Nuclear Information System (INIS)

    Choudhari, W.

    1995-01-01

    In this article, the author discusses the analysis of power sector system losses in both the countries which are similar in nature. The design and construction of major power plants, grid substations and transmission lines are constructed on the same pattern. The generation system loss under transmission must not exceed the limit and any loss above this limit could safely be taken as pilferage or theft of energy. The author is of the opinion that socio-economic conditions prevailing in both countries. The author is not in a position to analyse or comment on the causes of non-technical system loss in Pakistan, but he feels that some of the causes could also equally be applicable. (A.B.)

  3. Loss-of-coolant and loss-of-flow accident in the ITER-EDA first wall/blanket cooling system

    Energy Technology Data Exchange (ETDEWEB)

    Komen, E.M.J.; Koning, H.

    1995-05-01

    This report presents the analysis of the transient thermal-hydraulic system behaviour inside the first wall/blanket cooling system and the resulting temperature response inside the first wall and blanket of the ITER-EDA (International Thermonuclear Experimental Reactor - Engineering Design Activities) reactor design during a: - Loss-of-coolant accident caused by a reputure of the pump suction pipe; - loss-of-flow accident caused by a trip of the recirculation pump. (orig.).

  4. Loss-of-coolant and loss-of-flow accident in the ITER-EDA first wall/blanket cooling system

    International Nuclear Information System (INIS)

    Komen, E.M.J.; Koning, H.

    1995-05-01

    This report presents the analysis of the transient thermal-hydraulic system behaviour inside the first wall/blanket cooling system and the resulting temperature response inside the first wall and blanket of the ITER-EDA (International Thermonuclear Experimental Reactor - Engineering Design Activities) reactor design during a: - Loss-of-coolant accident caused by a reputure of the pump suction pipe; - loss-of-flow accident caused by a trip of the recirculation pump. (orig.)

  5. Methods and Tools for Profiling and Control of Distributed Systems

    Directory of Open Access Journals (Sweden)

    Sukharev Roman

    2017-01-01

    Full Text Available The article analyzes and standardizes methods for profiling distributed systems that focus on simulation to conduct experiments and build a graph model of the system. The theory of queueing networks is used for simulation modeling of distributed systems, receiving and processing user requests. To automate the above method of profiling distributed systems the software application was developed with a modular structure and similar to a SCADA-system.

  6. Ion heat conduction losses in Extrap

    International Nuclear Information System (INIS)

    Tennfors, E.

    1989-08-01

    The classical ion heat conduction losses in Extrap discharges are calculated using polynomial magnetic field profiles and compared to the power input. For polynomials matched to magnetic field profiles measured in present experiments, these losses are small. By varying the coefficients of the polynomials, a region is found, where the power input can balance the classical heat conduction losses. Each set of coefficients corresponds to values of the parameters F and Θ used in RFP physics. The region determines a region in an F-Θ diagram, including the usual RFP region but extending to higher values of Θ and βΘ

  7. Beam loss monitor system for machine protection

    CERN Document Server

    Dehning, B

    2005-01-01

    Most beam loss monitoring systems are based on the detection of secondary shower particles which depose their energy in the accelerator equipment and finally also in the monitoring detector. To allow an efficient protection of the equipment, the likely loss locations have to be identified by tracking simulations or by using low intensity beams. If superconducting magnets are used for the beam guiding system, not only a damage protection is required but also quench preventions. The quench levels for high field magnets are several orders of magnitude below the damage levels. To keep the operational efficiency high under such circumstances, the calibration factor between the energy deposition in the coils and the energy deposition in the detectors has to be accurately known. To allow a reliable damage protection and quench prevention, the mean time between failures should be high. If in such failsafe system the number of monitors is numerous, the false dump probability has to be kept low to keep a high operation...

  8. Design of the Beam Loss Monitoring System for the LHC Ring

    CERN Document Server

    Holzer, E B; Effinger, E; Ferioli, G; González, J L; Gschwendtner, E; Guaglio, Gianluca; Hodgson, M; Prieto, V; Zamantzas, C

    2004-01-01

    The beam loss monitoring (BLM) system of the LHC is one of the most critical elements for the protection of the LHC. It must prevent the super conducting magnets from quenches and the machine components from damages, caused by beam losses. It helps in the identification of the loss mechanism by measuring the loss pattern. Special detectors will be used for the setup and control of the collimators. Furthermore, it will be an important tool during machine setup and studies. The specification requirements of the BLM system include a very high reliability.

  9. Random-Profiles-Based 3D Face Recognition System

    Directory of Open Access Journals (Sweden)

    Joongrock Kim

    2014-03-01

    Full Text Available In this paper, a noble nonintrusive three-dimensional (3D face modeling system for random-profile-based 3D face recognition is presented. Although recent two-dimensional (2D face recognition systems can achieve a reliable recognition rate under certain conditions, their performance is limited by internal and external changes, such as illumination and pose variation. To address these issues, 3D face recognition, which uses 3D face data, has recently received much attention. However, the performance of 3D face recognition highly depends on the precision of acquired 3D face data, while also requiring more computational power and storage capacity than 2D face recognition systems. In this paper, we present a developed nonintrusive 3D face modeling system composed of a stereo vision system and an invisible near-infrared line laser, which can be directly applied to profile-based 3D face recognition. We further propose a novel random-profile-based 3D face recognition method that is memory-efficient and pose-invariant. The experimental results demonstrate that the reconstructed 3D face data consists of more than 50 k 3D point clouds and a reliable recognition rate against pose variation.

  10. Characteristics of possible beam losses in superconducting cyclotron

    International Nuclear Information System (INIS)

    Pradhan, J.; Paul, Santanu; Debnath, Jayanta; Dutta, Atanu; Bhunia, Uttam; Naser, Md. Zamal Abdul; Singh, Vinay; Agrawal, Ankur; Dey, Malay Kanti

    2015-01-01

    In a compact superconducting cyclotron large coherent oscillation and off-centering of the beam may cause large amount of beam loss. The off-centered beam may hit the beam chamber wall prohibiting extraction of the beam. Or it may hit the RF liner surfaces due to vertical blow-up across various resonances during acceleration. The vertical shift of beam caused by the mis-alignment gradually moves the beam out of geometrical median plane eventually leading to internal beam losses. The loss of isochronisms results the reduction of beam intensity depending on the particle phase history. Small field perturbations generated by trim coils have been used to identify the beam loss mechanisms in the superconducting cyclotron at out centre. Besides, the beam loss due to interaction of accelerating ions with residual gases is also discussed. The beam profile obtained from differential and three finger probes gives a clear insight of the loss-mechanism. The paper describes different beam losses observed in the cyclotron with corresponding beam profiles under different field perturbations, Special emphasis is given on characteristics features of beam-current profile to identify the cause of beam loss. (author)

  11. Characterization of the loss allocation techniques for radial systems with distributed generation

    International Nuclear Information System (INIS)

    Carpaneto, Enrico; Chicco, Gianfranco; Sumaili Akilimali, Jean

    2008-01-01

    In the restructured electricity industry, meaningful loss allocation methods are required in order to send correct signals to the market taking into account the location and characteristics of loads and generations, including the local sources forming the distributed generation (DG). This paper addresses the issues related to loss allocation in radial distribution systems with DG, with a three-fold focus. First, the key differences in the formulation of the loss allocation problem for radial distribution systems with respect to transmission systems are discussed, specifying the modeling and computational issues concerning the treatment of the slack node in radial distribution systems. Then, the characteristics of derivative-based and circuit-based loss allocation techniques are presented and compared, illustrating the arrangements used for adapting the various techniques to be applied to radial distribution systems with DG. Finally, the effects of introducing voltage-controllable local generation on the calculation of the loss allocation coefficients are discussed, proposing the adoption of a ''reduced'' representation of the system capable of taking into proper account the characteristics of the nodes containing voltage-controllable DG units. Numerical results are provided to show the time evolution of the loss allocation coefficients for distribution systems with variable load and local generation patterns. (author)

  12. Long-term effect of dexfenfluramine on amino acid profiles and food selection in obese patients during weight loss

    DEFF Research Database (Denmark)

    Breum, L.; Møller, S.-E.; Andersen, T.

    1996-01-01

    In depressive disorders an association between basal pre-treatment plasma ratios of tryptophan (Trp) and tyrosine (Tyr) to other large neutral amino acids (LNAA) and the clinical efficacy of serotonergic acting drugs have been established. In order to clarify whether a similar relation exists...... in obesity and to elucidate the long-term effect of dexfenfluramine (dF) on plasma amino acid profiles and macronutrient selection, we examined 29 obese patients participating in a 12 months double-blind weight loss trial with either dexfenfluramine (dF) (30 mg/day) or placebo (PL) in conjunction with 4...... groups. Macronutrient selection was not affected by the dF treatment. In the placebo group weight loss was associated with a high pre-treatment energy intake and a high carbohydrate-protein ratio (p

  13. About the complete loss of functions assumed by redundant systems

    International Nuclear Information System (INIS)

    Boaretto, Y.; Cayol, A.; Fourest, M.; Guimbail, H.

    1980-04-01

    Are to be taken into account situations resulting from loss of redundant safety systems. Two ways of approach were to be probed: evaluation of the failure probability and analysis of the consequences of those situations. The first way leads to improve reliability of concerned systems, the second way to set up mitigating means. Before TMI-2 occured, safety advices had already been issued about three kinds of situations: anticipated transients without scram, loss of ultimate heat sink, simultaneous loss of out-and inside power supplies. That, in some cases, something had to be done to improve safety showed the rightness of the concern. Next step is the study of the loss of both normal and emergency feedwater: The regulatory request has been issued on September 1979

  14. Evaluation of Control and Protection System for Loss of Electrical Power Supply System of Water-Cooling Nuclear Power Plant

    International Nuclear Information System (INIS)

    Suhaemi, Tjipta; Djen Djen; Setyono; Jambiar, Riswan; Rozali, Bang; Setyo P, Dwi; Tjahyono, Hendro

    2000-01-01

    Evaluation of control and protection system for loss of electrical power supply system of water-cooled nuclear power plant has been done. The loss of electrical power supply. The accident covered the loss of external electrical load and loss of ac power to the station auxiliaries. It is analysed by studying and observing the mechanism of electrical power system and mechanism of related control and protection system. The are two condition used in the evaluation i e without turbine trip and with turbine trip. From the evaluation it is concluded that the control and protection system can handled the failure caused by the loss of electrical power system

  15. Simulation-based seismic loss estimation of seaport transportation system

    International Nuclear Information System (INIS)

    Ung Jin Na; Shinozuka, Masanobu

    2009-01-01

    Seaport transportation system is one of the major lifeline systems in modern society and its reliable operation is crucial for the well-being of the public. However, past experiences showed that earthquake damage to port components can severely disrupt terminal operation, and thus negatively impact on the regional economy. The main purpose of this study is to provide a methodology for estimating the effects of the earthquake on the performance of the operation system of a container terminal in seaports. To evaluate the economic loss of damaged system, an analytical framework is developed by integrating simulation models for terminal operation and fragility curves of port components in the context of seismic risk analysis. For this purpose, computerized simulation model is developed and verified with actual terminal operation records. Based on the analytical procedure to assess the seismic performance of the terminal, system fragility curves are also developed. This simulation-based loss estimation methodology can be used not only for estimating the seismically induced revenue loss but also serve as a decision-making tool to select specific seismic retrofit technique on the basis of benefit-cost analysis

  16. Loss-of-Coolant and Loss-of-Flow Accidents in the SEAFP first wall/blanket cooling system

    International Nuclear Information System (INIS)

    Komen, E.M.J.; Koning, H.

    1995-01-01

    This paper presents the RELAP5/MOD3 thermal-hydraulic analysis of three Loss-of-Coolant Accidents (LOCAs) and three Loss-of-Flow Accidents (LOFAs) in the first wall/blanket cooling system of the SEAFP reactor design. The analyses deal with the transient thermal-hydraulic behaviour inside the cooling systems and the temperature development inside the nuclear components. As it appears, the temperature increase in the first wall Be-coating is limited to 30 K when an emergency plasma shutdown is initiated within 10 s following pump trip. (orig.)

  17. Loss-of-coolant and loss-of-flow accidents in the SEAFP first wall/blanket cooling system

    International Nuclear Information System (INIS)

    Komen, E.M.J.; Koning, H.

    1994-07-01

    This paper presents the RELAP5/MOD3 thermal-hydraulic analysis of three Loss-of-Coolant Accidents (LOCAs) and three Loss-of-Flow Accidents (LOFAs) in the first wall/blanket cooling system of the SEAFP reactor design. The analyses deal with the transient thermal-hydraulic behaviour inside the cooling systems and the temperature development inside the nuclear components. As it appears, the temperature increase in the first wall Be-coating is limited to 30 K when an emergency plasma shutdown is initiated within 10 s following pump trip. (orig.)

  18. Initial commissioning results from the APS loss monitor system

    International Nuclear Information System (INIS)

    Patterson, D.R.

    1996-01-01

    The design of the beam loss monitor system for the Argonne National Laboratory Advanced Photon Source is based on using a number of air dielectric coaxial cables as long ionization chambers. Results to date show that the loss monitor is useful in helping to determine the cause of injection losses and losses large enough to limit circulating currents in the storage ring to short lifetimes. Sensitivities ranging from 13 to 240 pC of charge collected in the injector BTS (booster-to-storage-ring) loss monitor per picocoulomb of loss have been measured, depending on the loss location. These results have been used to predict that the storage ring loss monitor leakage current limit of 10 pA per cable should allow detection of losses resulting in beam lifetimes of 100 hours or less with 100 mA stored beam. Significant DC bias levels associated with the presence of stored beam have been observed. These large bias levels are most likely caused by the loss monitor responding to hard x-ray synchrotron radiation. No such response to synchrotron radiation was observed during earlier tests at SSRL. However, the loss monitor response to average stored beam current in APS has provided a reasonable alternative to the DC current transformer (DCCT) for measuring beam lifetimes

  19. Molecular profiling reveals frequent gain of MYCN and anaplasia-specific loss of 4q and 14q in Wilms tumor.

    Science.gov (United States)

    Williams, Richard D; Al-Saadi, Reem; Natrajan, Rachael; Mackay, Alan; Chagtai, Tasnim; Little, Suzanne; Hing, Sandra N; Fenwick, Kerry; Ashworth, Alan; Grundy, Paul; Anderson, James R; Dome, Jeffrey S; Perlman, Elizabeth J; Jones, Chris; Pritchard-Jones, Kathy

    2011-12-01

    Anaplasia in Wilms tumor, a distinctive histology characterized by abnormal mitoses, is associated with poor patient outcome. While anaplastic tumors frequently harbour TP53 mutations, little is otherwise known about their molecular biology. We have used array comparative genomic hybridization (aCGH) and cDNA microarray expression profiling to compare anaplastic and favorable histology Wilms tumors to determine their common and differentiating features. In addition to changes on 17p, consistent with TP53 deletion, recurrent anaplasia-specific genomic loss and under-expression were noted in several other regions, most strikingly 4q and 14q. Further aberrations, including gain of 1q and loss of 16q were common to both histologies. Focal gain of MYCN, initially detected by high resolution aCGH profiling in 6/61 anaplastic samples, was confirmed in a significant proportion of both tumor types by a genomic quantitative PCR survey of over 400 tumors. Overall, these results are consistent with a model where anaplasia, rather than forming an entirely distinct molecular entity, arises from the general continuum of Wilms tumor by the acquisition of additional genomic changes at multiple loci. Copyright © 2011 Wiley Periodicals, Inc.

  20. Optimal Siting and Sizing of Multiple DG Units for the Enhancement of Voltage Profile and Loss Minimization in Transmission Systems Using Nature Inspired Algorithms

    Directory of Open Access Journals (Sweden)

    Ambika Ramamoorthy

    2016-01-01

    Full Text Available Power grid becomes smarter nowadays along with technological development. The benefits of smart grid can be enhanced through the integration of renewable energy sources. In this paper, several studies have been made to reconfigure a conventional network into a smart grid. Amongst all the renewable sources, solar power takes the prominent position due to its availability in abundance. Proposed methodology presented in this paper is aimed at minimizing network power losses and at improving the voltage stability within the frame work of system operation and security constraints in a transmission system. Locations and capacities of DGs have a significant impact on the system losses in a transmission system. In this paper, combined nature inspired algorithms are presented for optimal location and sizing of DGs. This paper proposes a two-step optimization technique in order to integrate DG. In a first step, the best size of DG is determined through PSO metaheuristics and the results obtained through PSO is tested for reverse power flow by negative load approach to find possible bus locations. Then, optimal location is found by Loss Sensitivity Factor (LSF and weak (WK bus methods and the results are compared. In a second step, optimal sizing of DGs is determined by PSO, GSA, and hybrid PSOGSA algorithms. Apart from optimal sizing and siting of DGs, different scenarios with number of DGs (3, 4, and 5 and PQ capacities of DGs (P alone, Q alone, and  P and Q both are also analyzed and the results are analyzed in this paper. A detailed performance analysis is carried out on IEEE 30-bus system to demonstrate the effectiveness of the proposed methodology.

  1. Optimal Siting and Sizing of Multiple DG Units for the Enhancement of Voltage Profile and Loss Minimization in Transmission Systems Using Nature Inspired Algorithms.

    Science.gov (United States)

    Ramamoorthy, Ambika; Ramachandran, Rajeswari

    2016-01-01

    Power grid becomes smarter nowadays along with technological development. The benefits of smart grid can be enhanced through the integration of renewable energy sources. In this paper, several studies have been made to reconfigure a conventional network into a smart grid. Amongst all the renewable sources, solar power takes the prominent position due to its availability in abundance. Proposed methodology presented in this paper is aimed at minimizing network power losses and at improving the voltage stability within the frame work of system operation and security constraints in a transmission system. Locations and capacities of DGs have a significant impact on the system losses in a transmission system. In this paper, combined nature inspired algorithms are presented for optimal location and sizing of DGs. This paper proposes a two-step optimization technique in order to integrate DG. In a first step, the best size of DG is determined through PSO metaheuristics and the results obtained through PSO is tested for reverse power flow by negative load approach to find possible bus locations. Then, optimal location is found by Loss Sensitivity Factor (LSF) and weak (WK) bus methods and the results are compared. In a second step, optimal sizing of DGs is determined by PSO, GSA, and hybrid PSOGSA algorithms. Apart from optimal sizing and siting of DGs, different scenarios with number of DGs (3, 4, and 5) and PQ capacities of DGs (P alone, Q alone, and P and Q both) are also analyzed and the results are analyzed in this paper. A detailed performance analysis is carried out on IEEE 30-bus system to demonstrate the effectiveness of the proposed methodology.

  2. A drop in the pond: the effect of rapid mass-loss on the dynamics and interaction rate of collisionless particles

    Science.gov (United States)

    Penoyre, Zephyr; Haiman, Zoltán

    2018-01-01

    In symmetric gravitating systems experiencing rapid mass-loss, particle orbits change almost instantaneously, which can lead to the development of a sharply contoured density profile, including singular caustics for collisionless systems. This framework can be used to model a variety of dynamical systems, such as accretion discs following a massive black hole merger and dwarf galaxies following violent early star formation feedback. Particle interactions in the high-density peaks seem a promising source of observable signatures of these mass-loss events (i.e. a possible EM counterpart for black hole mergers or strong gamma-ray emission from dark matter annihilation around young galaxies), because the interaction rate depends on the square of the density. We study post-mass-loss density profiles, both analytic and numerical, in idealized cases and present arguments and methods to extend to any general system. An analytic derivation is presented for particles on Keplerian orbits responding to a drop in the central mass. We argue that this case, with initially circular orbits, gives the most sharply contoured profile possible. We find that despite the presence of a set of singular caustics, the total particle interaction rate is reduced compared to the unperturbed system; this is a result of the overall expansion of the system dominating over the steep caustics. Finally, we argue that this result holds more generally, and the loss of central mass decreases the particle interaction rate in any physical system.

  3. Applications of nutrient profiling: potential role in diet-related chronic disease prevention and the feasibility of a core nutrient-profiling system.

    Science.gov (United States)

    Sacks, G; Rayner, M; Stockley, L; Scarborough, P; Snowdon, W; Swinburn, B

    2011-03-01

    A number of different nutrient-profiling models have been proposed and several applications of nutrient profiling have been identified. This paper outlines the potential role of nutrient-profiling applications in the prevention of diet-related chronic disease (DRCD), and considers the feasibility of a core nutrient-profiling system, which could be modified for purpose, to underpin the multiple potential applications in a particular country. The 'Four 'P's of Marketing' (Product, Promotion, Place and Price) are used as a framework for identifying and for classifying potential applications of nutrient profiling. A logic pathway is then presented that can be used to gauge the potential impact of nutrient-profiling interventions on changes in behaviour, changes in diet and, ultimately, changes in DRCD outcomes. The feasibility of a core nutrient-profiling system is assessed by examining the implications of different model design decisions and their suitability to different purposes. There is substantial scope to use nutrient profiling as part of the policies for the prevention of DRCD. A core nutrient-profiling system underpinning the various applications is likely to reduce discrepancies and minimise the confusion for regulators, manufacturers and consumers. It seems feasible that common elements, such as a standard scoring method, a core set of nutrients and food components, and defined food categories, could be incorporated as part of a core system, with additional application-specific criteria applying. However, in developing and in implementing such a system, several country-specific contextual and technical factors would need to be balanced.

  4. Automatic supervision and fault detection of PV systems based on power losses analysis

    Energy Technology Data Exchange (ETDEWEB)

    Chouder, A.; Silvestre, S. [Electronic Engineering Department, Universitat Politecnica de Catalunya, C/Jordi Girona 1-3, Campus Nord UPC, 08034 Barcelona (Spain)

    2010-10-15

    In this work, we present a new automatic supervision and fault detection procedure for PV systems, based on the power losses analysis. This automatic supervision system has been developed in Matlab and Simulink environment. It includes parameter extraction techniques to calculate main PV system parameters from monitoring data in real conditions of work, taking into account the environmental irradiance and module temperature evolution, allowing simulation of the PV system behaviour in real time. The automatic supervision method analyses the output power losses, presents in the DC side of the PV generator, capture losses. Two new power losses indicators are defined: thermal capture losses (L{sub ct}) and miscellaneous capture losses (L{sub cm}). The processing of these indicators allows the supervision system to generate a faulty signal as indicator of fault detection in the PV system operation. Two new indicators of the deviation of the DC variables respect to the simulated ones have been also defined. These indicators are the current and voltage ratios: R{sub C} and R{sub V}. Analysing both, the faulty signal and the current/voltage ratios, the type of fault can be identified. The automatic supervision system has been successfully tested experimentally. (author)

  5. Automatic supervision and fault detection of PV systems based on power losses analysis

    International Nuclear Information System (INIS)

    Chouder, A.; Silvestre, S.

    2010-01-01

    In this work, we present a new automatic supervision and fault detection procedure for PV systems, based on the power losses analysis. This automatic supervision system has been developed in Matlab and Simulink environment. It includes parameter extraction techniques to calculate main PV system parameters from monitoring data in real conditions of work, taking into account the environmental irradiance and module temperature evolution, allowing simulation of the PV system behaviour in real time. The automatic supervision method analyses the output power losses, presents in the DC side of the PV generator, capture losses. Two new power losses indicators are defined: thermal capture losses (L ct ) and miscellaneous capture losses (L cm ). The processing of these indicators allows the supervision system to generate a faulty signal as indicator of fault detection in the PV system operation. Two new indicators of the deviation of the DC variables respect to the simulated ones have been also defined. These indicators are the current and voltage ratios: R C and R V . Analysing both, the faulty signal and the current/voltage ratios, the type of fault can be identified. The automatic supervision system has been successfully tested experimentally.

  6. Profile updating for information systems

    International Nuclear Information System (INIS)

    Abrantes, J.F.

    1983-02-01

    Profiles updating methods were analysed. A method suitable to the characteristics of the system used in the research (SDI/CIN/CNEN) that uses as the selection criterio the threshold and weights criterion, was determined. Relevance weighting theory was described and experiments to verify precision were carried out. The improvements obtained were good nevertheless more significant tests are required to attain more reliable results. (Author) [pt

  7. Optical bi-sensorial measurement system for production control of extruded profiles

    Science.gov (United States)

    Weckenmann, A.; Bernstein, J.

    2008-09-01

    Extruded profiles are semi-finished products (made out of steel, brass, aluminum, synthetics...) which are appointed for wide applications in manufacturing of technical products. As yet used optical sensors in process control working to the shading technology detect the object's shadow orthographically to the axis of illumination. As a consequence they record it unattached by the profiles coat in measurement range at any point of the measured profile with high precision. As a matter of fact, concave zones cannot be captured. Alternatively the measurement of concave zones can be arranged by light-section systems. These do not comply with the required accuracy, are comparatively slow and moreover affected by dislocations of the section of the profile. A measurement system including a light-section and a shading system combines the advantages of both optical systems. It is to serve with a reliable conception for the assembly of a bi-sensorial measurement system consisting of both systems as well as suitable methods of analysis for the in-line inspection of concave profiles. As a result it contains conclusions concerning requirements of the light source, the arrangement of this source and the cameras, obtainable precision and sampling rate as well as the essential synchronization of both systems. After designing an appropriate prototype, the selected light-section system and the shading system will be synchronized and aligned. Therefore, the metered geometrical data will be merged for the evaluation of form deviation. So, developed and adapted software supports and contains proposals to the uncertainty after successful tests. The system and a calibration method will be proved in production where robustness will be a most critical despite of heat, dust and vibrations. The target uncertainty of less than 0.1 mm at every section of the profiles coat has to be met.

  8. Loss-of-load probabilities for stand-alone photovoltaic systems

    International Nuclear Information System (INIS)

    Klein, S.A.; Beckman, W.A.

    1989-01-01

    A general method is presented for estimating the loss-of-load probability of stand-alone photovoltaic systems. The method was developed by correlating simulation results. The simulations were driven with synthetic radiation sequences having the same statistical significance as available historical data. The methods assumes a constant nighttime load and accounts for the distribution and persistence in daily solar radiation data. It is shown that the 10 year average performance of systems having loss-of-load probabilities less than about 0.01 can vary greatly from one ten year period to the next and thereby cannot be considered realistic performance estimates of a system during its lifetime. (author). 26 refs, 15 figs, 4 tabs

  9. Analog front end circuit design of CSNS beam loss monitor system

    International Nuclear Information System (INIS)

    Xiao Shuai; Guo Xian; Tian Jianmin; Zeng Lei; Xu Taoguang; Fu Shinian

    2013-01-01

    The China Spallation Neutron Source (CSNS) beam loss monitor system uses gas ionization chamber to detect beam losses. The output signals from ionization chamber need to be processed in the analog front end circuit, which has been designed and developed independently. The way of transimpedance amplifier was used to achieve current-voltage (I-V) conversion measurement of signal with low repetition rate, low duty cycle and low amplitude. The analog front end circuit also realized rapid response to the larger beam loss in order to protect the safe operation of the accelerator equipment. The testing results show that the analog front end circuit meets the requirements of beam loss monitor system. (authors)

  10. FY 1997 Hanford telecommunication and informations system user profile, milestone IRM-097-003

    Energy Technology Data Exchange (ETDEWEB)

    Witherspoon, T.T.

    1997-09-22

    This document reports survey data collected from the U.S. Department of Energy, Richland Operations Office (DOE-RL), Project Hanford Management Contract (PHMC) companies, and the PHMC enterprise companies for purposes of characterizing the Hanford Local Area Network (HLAN) user profile. Telephone, radio, and pager data are also provided. The data reveal that job tasks of the 8,500 Hanford Site workers who use the HLAN are highly, if not completely, computer dependent. Employees use their computers as their pens and paper, calculators, drafting tables and communication devices. Fifty eight percent of the survey respondents predict 90 to 100% loss in productivity if they had no access to a computer. Additionally, 30% of the users felt they would have a 50 to 80% loss in productivity without computers; and more than 68 % use their computers between 4 and 8 hours per day. The profile also shows th at the software packages used most heavily are cc:Mail` the Windows version, Hanford Information, WordPerfece, Site Forms and Look-up. Use of Windows-based products is very high. Regarding the productivity tools that are seldom used, 49 % of the respondents say they ``never use`` the Hanford Help and Hints (HUH). The use of the external intemet by Hanford has shown a large increase. The survey indicates that users rate the intranet and the ability to access other sources of information as the fourth most important computer application. The Microsoft System Management Server (SMS 4) data show that more than 60% of the computers on the HLAN need replacement or upgrades to run the Windows 95 Operating System, which has been selected as the PHMC standard. Although data also show that 77% of the PHMC machines are running the current standard Windows for Workgroup version 3. 1 1, they do not have the memory and/or the hard disk space to upgrade to Windows 95. The survey results indicate that telephone system use is also high and regarded as a useful tool. Pager use is very high and

  11. Effect of weight loss on the cardiovascular risk profile of obese patients with psoriasis

    DEFF Research Database (Denmark)

    Jensen, Peter; Zachariae, Claus; Christensen, Robin

    2014-01-01

    Psoriasis is associated with obesity and other cardiovascular risk factors including endothelial dysfunction. We aimed to investigate the effects of weight loss on the cardiovascular risk profile of obese patients with psoriasis. A randomised controlled study was conducted in which we measured...... the microvascular endothelial function with peripheral arterial tonometry (PAT), selected plasma markers of endothelial function, and traditional cardiovascular risk factors in 60 obese patients with psoriasis. The participants were randomised to either low-energy diet (n = 30) providing 800-1,000 kcal/day for 8...... weeks followed by 8 weeks of reduced food intake reaching 1,200 kcal/day or normal healthy foods (n = 30) for 16 weeks. The intervention group lost significantly more weight than controls, which resulted in significant reductions of diastolic blood pressure, resting heart rate, total cholesterol, VLDL...

  12. Modelisation of synchrotron radiation losses in realistic tokamak plasmas

    International Nuclear Information System (INIS)

    Albajar, F.; Johner, J.; Granata, G.

    2000-08-01

    Synchrotron radiation losses become significant in the power balance of high-temperature plasmas envisaged for next step tokamaks. Due to the complexity of the exact calculation, these losses are usually roughly estimated with expressions derived from a plasma description using simplifying assumptions on the geometry, radiation absorption, and density and temperature profiles. In the present article, the complete formulation of the transport of synchrotron radiation is performed for realistic conditions of toroidal plasma geometry with elongated cross-section, using an exact method for the calculation of the absorption coefficient, and for arbitrary shapes of density and temperature profiles. The effects of toroidicity and temperature profile on synchrotron radiation losses are analyzed in detail. In particular, when the electron temperature profile is almost flat in the plasma center, as for example in ITB confinement regimes, synchrotron losses are found to be much stronger than in the case where the profile is represented by its best generalized parabolic approximation, though both cases give approximately the same thermal energy contents. Such an effect is not included in present approximate expressions. Finally, we propose a seven-variable fit for the fast calculation of synchrotron radiation losses. This fit is derived from a large database, which has been generated using a code implementing the complete formulation and optimized for massively parallel computing. (author)

  13. Systemic steroid reduces long-term hearing loss in experimental pneumococcal meningitis

    DEFF Research Database (Denmark)

    Worsøe, Lise Lotte; Brandt, C.T.; Lund, S.P.

    2010-01-01

    Sensorineural hearing loss is a common complication of pneumococcal meningitis. Treatment with corticosteroids reduces inflammatory response and may thereby reduce hearing loss. However, both experimental studies and clinical trials investigating the effect of corticosteroids on hearing loss have...... generated conflicting results. The objective of the present study was to determine whether systemic steroid treatment had an effect on hearing loss and cochlear damage in a rat model of pneumococcal meningitis.......Sensorineural hearing loss is a common complication of pneumococcal meningitis. Treatment with corticosteroids reduces inflammatory response and may thereby reduce hearing loss. However, both experimental studies and clinical trials investigating the effect of corticosteroids on hearing loss have...

  14. Systemic steroid reduces long-term hearing loss in experimental pneumococcal meningitis

    DEFF Research Database (Denmark)

    Worsøe, Lise Lotte; Brandt, C.T.; Lund, S.P.

    2010-01-01

    Sensorineural hearing loss is a common complication of pneumococcal meningitis. Treatment with corticosteroids reduces inflammatory response and may thereby reduce hearing loss. However, both experimental studies and clinical trials investigating the effect of corticosteroids on hearing loss have...... generated conflicting results. The objective of the present study was to determine whether systemic steroid treatment had an effect on hearing loss and cochlear damage in a rat model of pneumococcal meningitis....

  15. Automated design system for a rotor with an ellipse lobe profile

    International Nuclear Information System (INIS)

    Jung, Sung Yuen; Kim Chul; Han, Seung Moo; Cho, Hae Yong

    2009-01-01

    An internal lobe pump (ILP) is suitable for machine tool oil hydraulics, automotive engines, compressors, and various other devices. In particular, the ILP is an essential component of an automotive engine, used to feed lubricant oil through the system. The main components of an ILP are its rotors. The outer rotor is typically characterized by lobes with an elliptical shape, and the inner rotor profile is a conjugate to the outer profile. This paper describes a theoretical analysis of an ILP and the development of an integrated automated system for rotor design. This system is composed of three main modules and has been developed using AutoLISP for the AutoCAD program. The system generates a new lobe profile and automatically calculates flow rate and flow rate irregularity according to the lobe profile generated. Results obtained from the analysis can enable oil pump designers and manufacturers to become more efficient

  16. Automated design system for a rotor with an ellipse lobe profile

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Sung Yuen; Kim Chul [Pusan National University, Busan (Korea, Republic of); Han, Seung Moo [Kyung Hee University, Seoul (Korea, Republic of); Cho, Hae Yong [Chungbuk National University, Cheongju (Korea, Republic of)

    2009-11-15

    An internal lobe pump (ILP) is suitable for machine tool oil hydraulics, automotive engines, compressors, and various other devices. In particular, the ILP is an essential component of an automotive engine, used to feed lubricant oil through the system. The main components of an ILP are its rotors. The outer rotor is typically characterized by lobes with an elliptical shape, and the inner rotor profile is a conjugate to the outer profile. This paper describes a theoretical analysis of an ILP and the development of an integrated automated system for rotor design. This system is composed of three main modules and has been developed using AutoLISP for the AutoCAD program. The system generates a new lobe profile and automatically calculates flow rate and flow rate irregularity according to the lobe profile generated. Results obtained from the analysis can enable oil pump designers and manufacturers to become more efficient

  17. High Voltage Distribution System (HVDS) as a better system compared to Low Voltage Distribution System (LVDS) applied at Medan city power network

    Science.gov (United States)

    Dinzi, R.; Hamonangan, TS; Fahmi, F.

    2018-02-01

    In the current distribution system, a large-capacity distribution transformer supplies loads to remote locations. The use of 220/380 V network is nowadays less common compared to 20 kV network. This results in losses due to the non-optimal distribution transformer, which neglected the load location, poor consumer profile, and large power losses along the carrier. This paper discusses how high voltage distribution systems (HVDS) can be a better system used in distribution networks than the currently used distribution system (Low Voltage Distribution System, LVDS). The proposed change of the system into the new configuration is done by replacing a large-capacity distribution transformer with some smaller-capacity distribution transformers and installed them in positions that closest to the load. The use of high voltage distribution systems will result in better voltage profiles and fewer power losses. From the non-technical side, the annual savings and payback periods on high voltage distribution systems will also be the advantage.

  18. Intrinsic rotation produced by ion orbit loss and X-loss

    Energy Technology Data Exchange (ETDEWEB)

    Stacey, W. M. [Georgia Institute of Technology, Atlanta, Georgia 30332 (United States); Boedo, J. A. [University of California - San Diego, San Diego, California 92093 (United States); Evans, T. E.; Groebner, R. J. [General Atomics, San Diego, California 92186 (United States); Grierson, B. A. [Princeton Plasma Physics Laboratory, Princeton, New Jersey 08453 (United States)

    2012-11-15

    A practical calculation model for the intrinsic rotation imparted to the edge plasma by the directionally preferential loss of ions on orbits that cross the last closed flux surface is presented and applied to calculate intrinsic rotation in several DIII-D [J. Luxon, Nucl. Fusion 42, 614 (2002)] discharges. The intrinsic rotation produced by ion loss is found to be sensitive to the edge temperature and radial electric field profiles, which has implications for driving intrinsic rotation in future large tokamaks.

  19. Automatic hearing loss detection system based on auditory brainstem response

    International Nuclear Information System (INIS)

    Aldonate, J; Mercuri, C; Reta, J; Biurrun, J; Bonell, C; Gentiletti, G; Escobar, S; Acevedo, R

    2007-01-01

    Hearing loss is one of the pathologies with the highest prevalence in newborns. If it is not detected in time, it can affect the nervous system and cause problems in speech, language and cognitive development. The recommended methods for early detection are based on otoacoustic emissions (OAE) and/or auditory brainstem response (ABR). In this work, the design and implementation of an automated system based on ABR to detect hearing loss in newborns is presented. Preliminary evaluation in adults was satisfactory

  20. Reactive nitrogen losses from China's food system for the shared socioeconomic pathways (SSPs).

    Science.gov (United States)

    Wang, Mengru; Kroeze, Carolien; Strokal, Maryna; Ma, Lin

    2017-12-15

    Food production in China has been changing fast as a result of socio-economic development. This resulted in an increased use of nitrogen (N) in food production, and also to increased reactive nitrogen (Nr) losses to the environment, causing nitrogen pollution. Our study is the first to quantify future Nr losses from China's food system for the Shared Socio-economic Pathways (SSPs). We show that Nr losses differ largely among SSPs. We first qualitatively described the five SSP storylines for China with a focus on food production and consumption. Next, we interpreted these SSP scenarios quantitatively for 2030 and 2050, using the NUFER (NUtrient Flows in Food chains, Environment and Resources use) model to project the Nr losses from China's food system. The results indicate that Nr losses from future food system in China are relatively low for SSP1 and SSP2, and relatively high for SSP3 and SSP4. In SSP5 Nr losses from China's food system are projected to be slightly lower than the level of today. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. Loss of CDKL5 disrupts kinome profile and event-related potentials leading to autistic-like phenotypes in mice.

    Science.gov (United States)

    Wang, I-Ting Judy; Allen, Megan; Goffin, Darren; Zhu, Xinjian; Fairless, Andrew H; Brodkin, Edward S; Siegel, Steve J; Marsh, Eric D; Blendy, Julie A; Zhou, Zhaolan

    2012-12-26

    Mutations in the X-linked cyclin-dependent kinase-like 5 (CDKL5) gene have been identified in neurodevelopmental disorders including atypical Rett syndrome (RTT), autism spectrum disorders (ASDs), and early infantile epileptic encephalopathy. The biological function of CDKL5 and its role in the etiology of these disorders, however, remain unclear. Here we report the development of a unique knockout mouse model of CDKL5-related disorders and demonstrate that mice lacking CDKL5 show autistic-like deficits in social interaction, as well as impairments in motor control and fear memory. Neurophysiological recordings reveal alterations in event-related potentials (ERPs) similar to those observed in RTT and ASDs. Moreover, kinome profiling uncovers disruption of multiple signal transduction pathways, including the AKT-mammalian target of rapamycin (mTOR) cascade, upon Cdkl5 loss-of-function. These data demonstrate that CDKL5 regulates signal transduction pathways and mediates autistic-like phenotypes and together establish a causal role for Cdkl5 loss-of-function in neurodevelopmental disorders.

  2. Ayurvedic Profiling of Alzheimer's Disease.

    Science.gov (United States)

    Bredesen, Dale E; Rao, Rammohan V

    2017-05-01

    Alzheimer's disease (AD) is an age-associated, progressive neurodegenerative disease that is characterized by severe memory loss, personality changes, and an overall decline in cognitive function. The cause of AD is not yet completely defined and efforts to find a cure for it have so far been disappointing. AD is one of the most significant health care problems nationally and globally. Recently, we described a personalized therapeutic approach called metabolic enhancement for neurodegeneration (MEND) that successfully reversed the cognitive decline in patients with early AD. The magnitude of the improvement was exceptional, providing testimony to the fact that a personalized and programmatic approach to cognitive decline is highly effective. Ayurveda is a personalized system of traditional medicine native to India and the Indian subcontinent. Although a direct reference to AD in the ancient Ayurvedic literature is missing, concepts including forgetfulness, memory loss, and brain cell loss have been described. Using the clinical information and the metabolic profiling of AD individuals we recently reported using the MEND program, we now describe in this commentary, 3 subtypes of AD based on the Ayurvedic interpretation. Ayurvedic profiling of patients with AD reveals 3 readily distinguishable subtypes, namely Vata, Pitta, and Krimi, which will prove useful in patients with cognitive decline and those at risk for such decline from the standpoint of specific subtype-based Ayurvedic intervention.

  3. Loss of the CNA I secured river water system: analysis and effect evaluation

    International Nuclear Information System (INIS)

    Berra, Sandra; Guala, Mariana I.; Lorenzo, Andrea T.; Raffo Calderon, Maria C.; Urrutia, Guillermo

    1999-01-01

    In this work the evolution of the plant parameters is evaluated in the case of a loss of the secured circuit of river water (system UK). In particular the systems which are affected for this loss were studied. It was evaluated the functional degradation of these systems. (author)

  4. Future Integrated Systems Concept for Preventing Aircraft Loss-of-Control Accidents

    Science.gov (United States)

    Belcastro, Christine M.; Jacobson, Steven r.

    2010-01-01

    Loss of control remains one of the largest contributors to aircraft fatal accidents worldwide. Aircraft loss-of-control accidents are highly complex in that they can result from numerous causal and contributing factors acting alone or (more often) in combination. Hence, there is no single intervention strategy to prevent these accidents. This paper presents future system concepts and research directions for preventing aircraft loss-of-control accidents.

  5. Weight loss improves biomarkers endothelial function and systemic ...

    African Journals Online (AJOL)

    Background: Although postmenopausal associated disorders are important public health problems worldwide, to date limited studies evaluated the endothelial function and systemic inflammation response to weight loss in obese postmenopausal women. Objective: This study was done to evaluate the endothelial function ...

  6. Performance potential of mechanical ventilation systems with minimized pressure loss

    DEFF Research Database (Denmark)

    Terkildsen, Søren; Svendsen, Svend

    2013-01-01

    simulations that quantify fan power consumption, heating demand and indoor environmental conditions. The system was designed with minimal pressure loss in the duct system and heat exchanger. Also, it uses state-of-the-art components such as electrostatic precipitators, diffuse ceiling inlets and demand......In many locations mechanical ventilation has been the most widely used principle of ventilation over the last 50 years but the conventional system design must be revised to comply with future energy requirements. This paper examines the options and describes a concept for the design of mechanical...... ventilation systems with minimal pressure loss and minimal energy use. This can provide comfort ventilation and avoid overheating through increased ventilation and night cooling. Based on this concept, a test system was designed for a fictive office building and its performance was documented using building...

  7. Challenges of arbitrary waveform signal detection by Silicon Photomultipliers as readout for Cherenkov fibre based beam loss monitoring systems

    CERN Document Server

    Vinogradov, Sergey; Nebot del Busto, Eduardo; Kastriotou, Maria; Welsch, Carsten P

    2016-01-01

    Silicon Photomultipliers (SiPMs) are well recognised as very competitive photodetectors due to their exceptional photon number and time resolution, room-temperature low-voltage operation, insensitivity to magnetic fields, compactness, and robustness. Detection of weak light pulses of nanosecond time scale appears to be the best area for SiPM applications because in this case most of the SiPM drawbacks have a rather limited effect on its performance. In contrast to the more typical scintillation and Cherenkov detection applications, which demand information on the number of photons and/or the arrival time of the light pulse only, beam loss monitoring (BLM) systems utilising Cherenkov fibres with photodetector readout have to precisely reconstruct the temporal profile of the light pulse. This is a rather challenging task for any photon detector especially taking into account the high dynamic range of incident signals (100K – 1M) from a few photons to a few percents of destructive losses in a beam line and pre...

  8. Repetitive display system of line profiles for Doppler broadening measurement

    International Nuclear Information System (INIS)

    Mohri, A.; Narihara, K.; Haba, K.

    1982-10-01

    Line profiles of impurities in visible and ultraviolet regions are repetitively displayed on a CRT with an interval of 250 mu s or 500 mu s, using a system composed of a Czerny-Turner monochromator with 1 m F.L., a self-resonant optical scanner, a photomultiplier shielded against hard X-rays and electronic circuits. The profile resolution is 0.035 nm FWHM. This system can be used in the environment of strong hard X-rays. (author)

  9. Multi criteria evaluation for universal soil loss equation based on geographic information system

    Science.gov (United States)

    Purwaamijaya, I. M.

    2018-05-01

    The purpose of this research were to produce(l) a conceptual, functional model designed and implementation for universal soil loss equation (usle), (2) standard operational procedure for multi criteria evaluation of universal soil loss equation (usle) using geographic information system, (3) overlay land cover, slope, soil and rain fall layers to gain universal soil loss equation (usle) using multi criteria evaluation, (4) thematic map of universal soil loss equation (usle) in watershed, (5) attribute table of universal soil loss equation (usle) in watershed. Descriptive and formal correlation methods are used for this research. Cikapundung Watershed, Bandung, West Java, Indonesia was study location. This research was conducted on January 2016 to May 2016. A spatial analysis is used to superimposed land cover, slope, soil and rain layers become universal soil loss equation (usle). Multi criteria evaluation for universal soil loss equation (usle) using geographic information system could be used for conservation program.

  10. Beam profile diagnostics system for SDUV-FEL

    International Nuclear Information System (INIS)

    Xu Yichao; Han Lifeng; Chen Yongzhong

    2010-01-01

    A new beam profile diagnostics system for Shanghai Deep Ultraviolet Free Electron Laser (SDUV-FEL) has been developed based on industrial Ethernet, with good versatility and scalability. The system includes three major subsystems for image acquisition,pneumatic control and stepper motor control, respectively. Virtual instrument technology is adopted to drive the devices, and to develop the measurement software. In this paper,we describe the system structure, and its hardware and software design. The results of system commissioning are given as well. As an important diagnostic tool and data acquisition method, the system has been successfully applied to the measurement and control of the SDUV-FEL.(authors)

  11. Assessment of heat loss for RSG-GAS primary cooling system

    International Nuclear Information System (INIS)

    Dibyo, S.

    1998-01-01

    Heat Loss is part term of energy balance equation of system, therefore heat loss very important thing in the thermal dynamic analysis. Heat energy loosed from the surface pipe to the air in the room was calculated. Heat energy pass through by conduction, convection and radiation. The convection process are caused by moving of air density, i.e up flow of the hot air return to be down flow. The heat transfer phenomenon could be determined by empirical correlation of Heilman. The primary cooling system is consisted to the 3 zone : 1). Zone of (safety valves-heat exchanger), 2). Zone of heat exchanger surfaces, 3). Zone of heat exchanger-reactor pool. By using input data of air temperature are about 25 o C, temperature of primary coolant about 45 o C, The heat Loss along the pipes to the air are 23.9 k watt or 0.1%

  12. Power system reconfiguration in a radial distribution network for reducing losses and to improve voltage profile using modified plant growth simulation algorithm with Distributed Generation (DG

    Directory of Open Access Journals (Sweden)

    R. Rajaram

    2015-11-01

    Full Text Available Network reconfiguration which is constrained non linear optimization problem has been solved for loss minimization, load balancing, etc. for last two decades using various heuristic search evolutionary algorithms like binary particle swarm optimization, neuro-fuzzy techniques, etc. The contribution of this paper lies in considering distributed generation which are smaller power sources like solar photovoltaic cells or wind turbines connected in the customer roof top. This new connection in the radial network has made unidirectional current flow to become bidirectional there by increasing the efficiency but sometimes reducing stability of the system. Modified plant growth simulation algorithm has been applied here successfully to minimize real power loss because it does not require barrier factors or cross over rates because the objectives and constraints are dealt separately. The main advantage of this algorithm is continuous guiding search along with changing objective function because power from distributed generation is continuously varying so this can be applied for real time applications with required modifications. This algorithm here is tested for a standard 33 bus radial distribution system for loss minimization and test results here shows that this algorithm is efficient and suitable for real time applications.

  13. Self-consistent analysis of radial electric field and fast ion losses in CHS Torsatron/Heliotron

    International Nuclear Information System (INIS)

    Sanuki, H.; Itoh, K.; Itoh, S.

    1992-09-01

    A self-consistent analysis is developed to determine the radial electric field and loss cone boundary in Torsatron/Heliotron plasmas under the influence of non-classical ion losses such as the loss cone loss ans charge exchange loss of fast ions with neutrals. Analysis is applied to the NBI heated plasmas in the Compact Helical System (CHS) device. Comparison is made between theoretical results and experimental observations. The increased ion particle losses caused by the orbit loss and charge exchange loss with neutrals make the radial electric field more negative than the value of purely neoclassical calculation. The partition of the injection energy among the shine through, direct orbit loss, change exchange loss and bulk heating is evaluated by using the self-consistent electric field profile. On-going experiments in the CHS device are briefly introduced. (author)

  14. H-Infinity Control Design Considering Packet Loss as a Disturbance for Networked Control Systems

    OpenAIRE

    OGURA, Takashi; KOBAYASHI, Kentaro; OKADA, Hiraku; KATAYAMA, Masaaki

    2017-01-01

    This paper studies H∞ control for networked control systems with packet loss. In networked control systems, packet loss is one of major weakness because the control performance deteriorates due to packet loss. H∞ control, which is one of robust control, can design a controller to reduce the influence of disturbances acting on the controlled object. This paper proposes an H∞ control design that considers packet loss as a disturbance. Numerical examples show that the proposed H∞ control design ...

  15. Implementation of Bluetooth serial port based profiles in embedded systems

    Science.gov (United States)

    Liu, Guanglei; Qiu, Zhengding; Wang, Quanping; Gao, Qiang

    2001-10-01

    Bluetooth is a new short-range wireless communication technology developing rapidly in recent years. Bluetooth software architecture consists of stack and profiles. Serial Port Profile (SPP) is an underlying profile that emulates RS232 serial cable connections between two peer devices. Based on SPP, Dial-up Networking (DUN) Profile establishes PPP connection with remote dial-up server, Fax Profile realizes document facsimile function and LAN Access Profile (LAP) provides local area network access service. When it comes to their implementation in embedded systems, there are several challenges such as memory consumption, code efficiency, code reliability, and code portability onto different OS and hardware platforms to be attacked. In this paper, we propose integrated software architecture after discussing the great similarities shared among the three SPP based profiles. Then implementation of the architecture is given, in which OS-dependent and OS-independent parts are clearly separated. Profile interfaces with stack and OS are specified respectively so that the three profiles as a whole can be ported onto various software and hardware platforms easily. As a result, policy of transplanting our implementation onto different platforms is addressed at the end of the paper.

  16. Seabed resident event driven profiling system (SREP). Concept, design and tests

    Digital Repository Service at National Institute of Oceanography (India)

    Mascarenhas, A.A.M.Q.; Afzulpurkar, S.; Maurya, P.K.; Fernandes, L.; Madhan, R.; Desa, E.S.; Dabolkar, N.A.; Navelkar, G.S.; Naik, L.; Shetye, V.G.; Shetty, N.B.; Prabhudesai, S.P.; Nagvekar, S.; Vimalakumari, D.

    The seabed resident event driven profiling system (SREP) described here offers a novel, optimized approach to profiling in coastal waters from seabed to sea surface during the rough seas encountered in the southwest monsoon season (June...

  17. Cover Crops and Fertilization Alter Nitrogen Loss in Organic and Conventional Conservation Agriculture Systems

    Science.gov (United States)

    Shelton, Rebecca E.; Jacobsen, Krista L.; McCulley, Rebecca L.

    2018-01-01

    Agroecosystem nitrogen (N) loss produces greenhouse gases, induces eutrophication, and is costly for farmers; therefore, conservation agricultural management practices aimed at reducing N loss are increasingly adopted. However, the ecosystem consequences of these practices have not been well-studied. We quantified N loss via leaching, NH3 volatilization, N2O emissions, and N retention in plant and soil pools of corn conservation agroecosystems in Kentucky, USA. Three systems were evaluated: (1) an unfertilized, organic system with cover crops hairy vetch (Vicia villosa), winter wheat (Triticum aestivum), or a mix of the two (bi-culture); (2) an organic system with a hairy vetch cover crop employing three fertilization schemes (0 N, organic N, or a fertilizer N-credit approach); and (3) a conventional system with a winter wheat cover crop and three fertilization schemes (0 N, urea N, or organic N). In the unfertilized organic system, cover crop species affected NO3-N leaching (vetch > bi-culture > wheat) and N2O-N emissions and yield during corn growth (vetch, bi-culture > wheat). Fertilization increased soil inorganic N, gaseous N loss, N leaching, and yield in the organic vetch and conventional wheat systems. Fertilizer scheme affected the magnitude of growing season N2O-N loss in the organic vetch system (organic N > fertilizer N-credit) and the timing of loss (organic N delayed N2O-N loss vs. urea) and NO3-N leaching (urea >> organic N) in the conventional wheat system, but had no effect on yield. Cover crop selection and N fertilization techniques can reduce N leaching and greenhouse gas emissions without sacrificing yield, thereby enhancing N conservation in both organic and conventional conservation agriculture systems. PMID:29403512

  18. Cover Crops and Fertilization Alter Nitrogen Loss in Organic and Conventional Conservation Agriculture Systems

    Directory of Open Access Journals (Sweden)

    Rebecca E. Shelton

    2018-01-01

    Full Text Available Agroecosystem nitrogen (N loss produces greenhouse gases, induces eutrophication, and is costly for farmers; therefore, conservation agricultural management practices aimed at reducing N loss are increasingly adopted. However, the ecosystem consequences of these practices have not been well-studied. We quantified N loss via leaching, NH3 volatilization, N2O emissions, and N retention in plant and soil pools of corn conservation agroecosystems in Kentucky, USA. Three systems were evaluated: (1 an unfertilized, organic system with cover crops hairy vetch (Vicia villosa, winter wheat (Triticum aestivum, or a mix of the two (bi-culture; (2 an organic system with a hairy vetch cover crop employing three fertilization schemes (0 N, organic N, or a fertilizer N-credit approach; and (3 a conventional system with a winter wheat cover crop and three fertilization schemes (0 N, urea N, or organic N. In the unfertilized organic system, cover crop species affected NO3-N leaching (vetch > bi-culture > wheat and N2O-N emissions and yield during corn growth (vetch, bi-culture > wheat. Fertilization increased soil inorganic N, gaseous N loss, N leaching, and yield in the organic vetch and conventional wheat systems. Fertilizer scheme affected the magnitude of growing season N2O-N loss in the organic vetch system (organic N > fertilizer N-credit and the timing of loss (organic N delayed N2O-N loss vs. urea and NO3-N leaching (urea >> organic N in the conventional wheat system, but had no effect on yield. Cover crop selection and N fertilization techniques can reduce N leaching and greenhouse gas emissions without sacrificing yield, thereby enhancing N conservation in both organic and conventional conservation agriculture systems.

  19. A simple data loss model for positron camera systems

    International Nuclear Information System (INIS)

    Eriksson, L.; Dahlbom, M.

    1994-01-01

    A simple model to describe data losses in PET cameras is presented. The model is not intended to be used primarily for dead time corrections in existing scanners, although this is possible. Instead the model is intended to be used for data simulations in order to determine the figures of merit of future camera systems, based on data handling state-of-art solutions. The model assumes the data loss to be factorized into two components, one describing the detector or block-detector performance and the other the remaining data handling such as coincidence determinations, data transfer and data storage. Two modern positron camera systems have been investigated in terms of this model. These are the Siemens-CTI ECAT EXACT and ECAT EXACT HR systems, which both have an axial field-of-view (FOV) of about 15 cm. They both have retractable septa and can acquire data from the whole volume within the FOV and can reconstruct volume image data. An example is given how to use the model for live time calculation in a futuristic large axial FOV cylindrical system

  20. Earthquake loss estimation for a gas lifeline transportation system in Colombia

    Energy Technology Data Exchange (ETDEWEB)

    Yamin, L.E.; Arambula, S.; Reyes, J.C. [Universidad de los Andes, Bogota (Colombia). Centro de Innovacion y Desarrollo Tecnologico; Belage, S.; Vega, A.; Gil, W. [TransGas de Occidente S.A., Bogota (Colombia)

    2004-07-01

    Methodologies are needed to estimate the seismic risk facing natural gas distribution systems in Colombia in order to establish insurance strategies, risk assessments and emergency plans. This study estimated the maximum probable losses associated with Colombia's 770 km long gas transportation system which stretches from Mariquita to Cali. The pipeline is vulnerable to seismic events, volcanic eruptions, extreme hydrological conditions, and their associated effects such as landslides, liquefaction and avalanches. A geographic information system (GIS) which includes seismic, volcanic, landslide and liquefaction hazards was used to estimate earthquake loss estimates for the natural gas distribution system. Elastic and inelastic finite element methods were used to evaluate the vulnerability of pipelines, bridges, underground crossings and valves. The results were incorporated into the GIS and were used to quantify the probable maximum losses for the system, the most critical associated event, the system's critical zones and the probable damage scenarios. The information was used to define insurance strategies, emergency and contingency plans. It was concluded that due to natural hazards, the natural gas distribution system is at moderate risk despite the low vulnerability of its components. Volcanic eruptions and large earthquakes could produce indirect phenomena such as landslides and liquefaction which could greatly influence the system and which would require adequate risk management. 14 refs., 1 tab., 8 figs.

  1. 110 kV NETWORK TECHNICAL LOSSES ASSESSMENT. REAL DISTRIBUTION SYSTEM CASE STUDY

    Directory of Open Access Journals (Sweden)

    BARBULESCU C.

    2015-06-01

    Full Text Available The paper is focusing on evaluating the technical losses within a real distribution network. The study was conducted for a distribution system operator within the Romanian Power System. The analysed area is represented by a real part of the Romanian Power System. It is modelled in a computer aided power system analysis tool. Several power system operating conditions are analysed. Power system optimization measures are provided having as a goal to reduce the technical losses' value. Values obtained based on the field measurement are compared to the ones provided by computer simulations. These conclusions are very useful for the distribution network operator.

  2. Quantitative Analysis Method of Output Loss due to Restriction for Grid-connected PV Systems

    Science.gov (United States)

    Ueda, Yuzuru; Oozeki, Takashi; Kurokawa, Kosuke; Itou, Takamitsu; Kitamura, Kiyoyuki; Miyamoto, Yusuke; Yokota, Masaharu; Sugihara, Hiroyuki

    Voltage of power distribution line will be increased due to reverse power flow from grid-connected PV systems. In the case of high density grid connection, amount of voltage increasing will be higher than the stand-alone grid connection system. To prevent the over voltage of power distribution line, PV system's output will be restricted if the voltage of power distribution line is close to the upper limit of the control range. Because of this interaction, amount of output loss will be larger in high density case. This research developed a quantitative analysis method for PV systems output and losses to clarify the behavior of grid connected PV systems. All the measured data are classified into the loss factors using 1 minute average of 1 second data instead of typical 1 hour average. Operation point on the I-V curve is estimated to quantify the loss due to the output restriction using module temperature, array output voltage, array output current and solar irradiance. As a result, loss due to output restriction is successfully quantified and behavior of output restriction is clarified.

  3. CAMEX-3 AIRBORNE VERTICAL ATMOSPHERE PROFILING SYSTEM (AVAPS) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The CAMEX-3 DC-8 Airborne Vertical Atmosphere Profiling System (AVAPS) uses dropwindsonde and Global Positioning System (GPS) receivers to measure the atmospheric...

  4. Mild-moderate congenital hearing loss: secular trends in outcomes across four systems of detection.

    Science.gov (United States)

    Carew, P; Mensah, F K; Rance, G; Flynn, T; Poulakis, Z; Wake, M

    2018-01-01

    Universal newborn hearing screening (UNHS) targets moderate or greater hearing loss. However, UNHS also frequently detects children with mild loss that results in many receiving early treatment. The benefits of this approach are not yet established. We aimed to (i) compare language and psychosocial outcomes between four hearing loss detection systems for children aged 5-8 years with congenital mild-moderate hearing loss; (ii) determine whether age of detection predicts outcomes; and (iii) compare outcomes between children identified via well-established UNHS and the general population. Linear regression adjusted for potential confounding factors was used throughout. Via a quasi-experimental design, language and psychosocial outcomes were compared across four population-based Australian systems of hearing loss detection: opportunistic detection, born 1991-1993, n = 50; universal risk factor referral, born 2003-2005, n = 34; newly established UNHS, born 2003-2005, n = 41; and well-established UNHS, born 2007-2010, n = 21. In pooled analyses, we examined whether age of detection predicted outcomes. Outcomes were similarly compared between the current well-established UNHS system and typically developing children in the Early Language in Victoria Study, born 2003, n = 1217. Age at diagnosis and hearing aid fitting fell steadily across the four systems. For moderate losses, mean expressive language (P for trend .05) and receptive vocabulary (P for trend .06) improved across the four systems, but benefit was not obvious for mild losses. In pooled analyses, diagnosis before age six months predicted better language outcomes for moderate losses. Children with mild-moderate losses exposed to well-established UNHS continue to experience expressive language scores well below children in the general population (adjusted mean difference -8.9 points, 95% CI -14.7 to -3.1). Treatment arising from UNHS appears to be clearly benefitting children with moderate hearing

  5. 137Cs profiles in erosion plots with different soil cultivation

    International Nuclear Information System (INIS)

    Andrello, A.C.; Appoloni, C.R.; Cassol, E.A.; Melquiades, F.L.

    2006-01-01

    Cesium-137 methodology has been successfully used to assess soil erosion. Seven erosion plots were sampled to determine the 137 Cs profile and to assess the erosion rates. Cesium-137 profile for native pasture plot showed an exponential decline below 5 cm depth, with little 137 Cs activity in the superficial layer (0-5 cm). Cesium-137 profile for wheat-soybean rotation plot in conventional tillage showed a uniform distribution with depth. For this plot, the soil loss occurs more in middle than upper and lower level. Cesium-137 profile for wheat-soybean rotation and wheat-maize rotation plots in no-tillage showed a similar result to the native pasture, with a minimum soil loss in the superficial layer. Cesium-137 profile for bare soil and cultivated pasture plots are similar, with a soil erosion rate of 229 t ha -1 year -1 . In the plots with a conventional tillage a greater soil loss occur in middle than upper and lower level. In no-tillage cultivation plots occurs soil loss in lower level, but no sign of soil loss neither gain in the upper level is observed. Cesium-137 methodology is a good tool to assess soil erosion and the 137 Cs profile gives a possibility to understand the soil erosion behavior in erosion plots. (author)

  6. Synthesis of national risk profile

    Science.gov (United States)

    1979-01-01

    The methodology used and results obtained in computing the national risk profile for carbon fibers (CF) released after an aircraft accident (fire or explosion) are presented. The computation was performed by use of twenty-six individual conditional risk profiles, together with the extrapolation of these profiles to other U.S. airports. The risk profile was obtained using 1993 CF utilization forecasts, but numbers of facilities were taken from 1972 and 1975 census data, while losses were expressed in 1977 dollars.

  7. Losses at magnetic nulls in pulsed-power transmission line systems

    International Nuclear Information System (INIS)

    Mendel, C.W. Jr.; Pointon, T.D.; Savage, M.E.; Seidel, D.B.; Magne, I.; Vezinet, R.

    2006-01-01

    Pulsed-power systems operating in the terawatt regime must deal with large electron flows in vacuum transmission lines. In most parts of these transmission lines the electrons are constrained by the self-magnetic field to flow parallel to the conductors. In very low impedance systems, such as those used to drive Z-pinch radiation sources, the currents from multiple transmission lines are added together. This addition necessarily involves magnetic nulls that connect the positive and negative electrodes. The resultant local loss of magnetic insulation results in electron losses at the anode in the vicinity of the nulls. The lost current due to the magnetic null might or might not be appreciable. In some cases the lost current due to the null is not large, but is spatially localized, and may create a gas and plasma release from the anode that can lead to an excessive loss, and possibly to catastrophic damage to the hardware. In this paper we describe an analytic model that uses one geometric parameter (aside from straightforward hardware size measurements) that determines the loss to the anode, and the extent of the loss region when the driving source and load are known. The parameter can be calculated in terms of the magnetic field in the region of the null calculated when no electron flow is present. The model is compared to some experimental data, and to simulations of several different hardware geometries, including some cases with multiple nulls, and unbalanced feeds

  8. A UML profile for code generation of component based distributed systems

    International Nuclear Information System (INIS)

    Chiozzi, G.; Karban, R.; Andolfato, L.; Tejeda, A.

    2012-01-01

    A consistent and unambiguous implementation of code generation (model to text transformation) from UML (must rely on a well defined UML (Unified Modelling Language) profile, customizing UML for a particular application domain. Such a profile must have a solid foundation in a formally correct ontology, formalizing the concepts and their relations in the specific domain, in order to avoid a maze or set of wildly created stereotypes. The paper describes a generic profile for the code generation of component based distributed systems for control applications, the process to distill the ontology and define the profile, and the strategy followed to implement the code generator. The main steps that take place iteratively include: defining the terms and relations with an ontology, mapping the ontology to the appropriate UML meta-classes, testing the profile by creating modelling examples, and generating the code. This has allowed us to work on the modelling of E-ELT (European Extremely Large Telescope) control system and instrumentation without knowing what infrastructure will be finally used

  9. Application of MySQL in instantaneous profile gauge system

    International Nuclear Information System (INIS)

    Guo Xiaojing; Miao Jichen; Wu Zhifang

    2011-01-01

    As equipment in the hot rolling plate plant for online measurement of strip steel, the instantaneous profile gauge is used to measure instant crown of hot rolling strips and feed back the crown to the rolling mill to adjust strip profile. During the measurement, a large amount of data need to be stored reasonably for query, display, computation and other processing, while a database management software can make it happen. Based on such features of MySQL as small size, fast speed, low cost and open source codes, a database function was implemented in the instantaneous profile gauge for data storage, query and maintenance, by applying MySQL database management system and integrating with the control interface. (authors)

  10. Eating patterns and food choice as determinant of weight loss and improvement of metabolic profile after RYGB.

    Science.gov (United States)

    Molin Netto, Bárbara Dal; Earthman, Carrie P; Farias, Gisele; Landi Masquio, Deborah Cristina; Grotti Clemente, Ana Paula; Peixoto, Priscilla; Bettini, Solange Cravo; von Der Heyde, Maria Emilia; Dâmaso, Ana R

    2017-01-01

    Significant changes in the preference for different dietary components have been observed after Roux-en-Y gastric bypass (RYGB). The aim of this study was to evaluate the early post-RYGB changes in quality of eating patterns and their relationship to weight loss and metabolic parameters. The sample was composed of 41 extremely obese individuals undergoing RYGB. Dietary data were collected using a validated food frequency questionnaire in Brazil. A food intake evaluation was conducted with a focus on the frequency of consumption (≥4 times/wk) of markers for healthy eating and markers for unhealthy eating. Furthermore, anthropometric and metabolic markers were collected before surgery and 6 mo post-RYGB. Compared with baseline, the postsurgery body mass index was reduced by 12.9 kg/m 2 , corresponding to an excess weight loss of 63.5%. Blood glucose, insulin, ferritin, cholesterol, low-density lipoprotein-cholesterol, triacylglycerol (TG), and hemoglobin were reduced 6 mo after RYGB (P hamburger), and some healthy food increased (e.g., from 0% to 5.1% for fish and from 0% to 25.6% for plain yogurt). There was a decrease in the frequency of individuals who reported consuming fruit and vegetables. Conversely, insulin, glucose, and TG levels were positively associated with intake of chocolates/truffles and ice cream/sundaes. Participants in the present study appeared to develop a healthier dietary pattern by 6 mo after RYGB. These results show that a healthier dietary pattern is associated with a significant improvement of metabolic profile and weight loss. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Allocation of losses in distribution system with dispersed generation of electricity

    International Nuclear Information System (INIS)

    Atanasovski, Metodija B.

    2005-01-01

    The problem of allocation of losses in distribution systems with dispersed generation (DG) of electricity is considered in this work. Definition of category DG, overview of technologies which belongs to this category and main features of each technology are given. Modeling of DG in steady state analysis of distribution networks is completely elaborated. Requirements for ideal allocation of losses are summarized. Methods from the literature, for allocation of losses in distribution systems with DG, are elaborated, as: classical distribution pricing method, substitution method, marginal loss coefficients method and nodal factors pricing method. In this work a new method for allocation of losses in distribution systems with DG is also presented. The new method is based on branches and resolves the problems of implementation of branch based methods for transmission networks to distribution networks. The method establishes direct relationship between losses in each branch of the network and injected active and reactive power in the nodes on which path to the root node the branch is placed. Reactive power is considered in the loss allocation process in this method and allocation of crossed terms of active and reactive power is performed using quadratic allocation of crossed terms. DG in this method is treated as negative power injection. It is assumed that the network is radial and the power flow in each branch of the, distribution network is constant and equal to the sum of injected active and reactive power in each node on which path to the root node, the branch is placed. The network is considered loss less. The new proposed method is applied and tested on real distribution network which is a part of Distribution company-Bitola. One distribution feeder of power station 110/10 kV/kV Bitola 4 is considered. Different types of consumers and two small hydro power plants in property of JP Strezevo as typical representatives of DG are connected to the feeder. Results

  12. HuH-7 reference genome profile: complex karyotype composed of massive loss of heterozygosity.

    Science.gov (United States)

    Kasai, Fumio; Hirayama, Noriko; Ozawa, Midori; Satoh, Motonobu; Kohara, Arihiro

    2018-05-17

    Human cell lines represent a valuable resource as in vitro experimental models. A hepatoma cell line, HuH-7 (JCRB0403), has been used extensively in various research fields and a number of studies using this line have been published continuously since it was established in 1982. However, an accurate genome profile, which can be served as a reliable reference, has not been available. In this study, we performed M-FISH, SNP microarray and amplicon sequencing to characterize the cell line. Single cell analysis of metaphases revealed a high level of heterogeneity with a mode of 60 chromosomes. Cytogenetic results demonstrated chromosome abnormalities involving every chromosome in addition to a massive loss of heterozygosity, which accounts for 55.3% of the genome, consistent with the homozygous variants seen in the sequence analysis. We provide empirical data that the HuH-7 cell line is composed of highly heterogeneous cell populations, suggesting that besides cell line authentication, the quality of cell lines needs to be taken into consideration in the future use of tumor cell lines.

  13. Analysis of fast losses in the LHC with the BLM system

    CERN Document Server

    Nebot, E; Holzer, E; Dehning, B; Nordt, A; Sapinski, M; Emery, J; Zamantzas, C; Effinger, E; Marsili, A; Wenninger, J; Baer, T; Schmidt, R; Yang, Z; Zimmerman, F; Fuster, N

    2011-01-01

    About 3600 Ionization Chambers are located around the LHC ring to detect beam losses that could damage the equipment or quench superconducting magnets. The Beam Loss Monitors (BLMs) integrate the losses in 12 different time intervals (from 40 us to 83.8 s) allowing for different abort thresholds depending on the duration of the loss and the beam energy. The signals are also recorded in a database at 1 Hz for offline analysis. During the 2010 run, a limiting factor in the machine availability were sudden losses appearing around the ring on the ms time scale and detected exclusively by the BLM system. It is believed that such losses originate from dust particles falling into the beam, or being attracted by its strong electromagnetic field. This document describes some of the properties of these ”Unidentified Falling Objects” (UFOs) putting special emphasis on their dependence on beam parameters (energy, intensity, etc). The subsequent modification of the BLM beam abort thresholds for the 2011 run that were ...

  14. Control of Refrigeration Systems for Trade-off between Energy Consumption and Food Quality Loss

    DEFF Research Database (Denmark)

    Cai, Junping

    In supermarkets, control strategies determine both the energy consumption of refrigeration systems and the quality loss of refrigerated foodstuffs. The question is, what can be done to optimize the balance between quality loss and energy consumption? This thesis tries to answer this question...... by applying two main optimization strategies to traditional refrigeration systems. The first strategy is a new defrost-on-demand scheme, which based on an objective function between quality loss and energy consumption, continuously seeks an optimal time interval for defrosting in dynamic situation. The second...... strategy is through utilization of the thermal mass of the refrigerated foodstuffs, the day-night temperature variation and the capacity control of the compressor, to realize a trade-off between system energy consumption and food quality loss....

  15. Internet-based Profiler system as integrative framework to support translational research.

    Science.gov (United States)

    Kim, Robert; Demichelis, Francesca; Tang, Jeffery; Riva, Alberto; Shen, Ronglai; Gibbs, Doug F; Mahavishno, Vasudeva; Chinnaiyan, Arul M; Rubin, Mark A

    2005-12-19

    Translational research requires taking basic science observations and developing them into clinically useful tests and therapeutics. We have developed a process to develop molecular biomarkers for diagnosis and prognosis by integrating tissue microarray (TMA) technology and an internet-database tool, Profiler. TMA technology allows investigators to study hundreds of patient samples on a single glass slide resulting in the conservation of tissue and the reduction in inter-experimental variability. The Profiler system allows investigator to reliably track, store, and evaluate TMA experiments. Here within we describe the process that has evolved through an empirical basis over the past 5 years at two academic institutions. The generic design of this system makes it compatible with multiple organ system (e.g., prostate, breast, lung, renal, and hematopoietic system,). Studies and folders are restricted to authorized users as required. Over the past 5 years, investigators at 2 academic institutions have scanned 656 TMA experiments and collected 63,311 digital images of these tissue samples. 68 pathologists from 12 major user groups have accessed the system. Two groups directly link clinical data from over 500 patients for immediate access and the remaining groups choose to maintain clinical and pathology data on separate systems. Profiler currently has 170 K data points such as staining intensity, tumor grade, and nuclear size. Due to the relational database structure, analysis can be easily performed on single or multiple TMA experimental results. The TMA module of Profiler can maintain images acquired from multiple systems. We have developed a robust process to develop molecular biomarkers using TMA technology and an internet-based database system to track all steps of this process. This system is extendable to other types of molecular data as separate modules and is freely available to academic institutions for licensing.

  16. Tile drainage phosphorus loss with long-term consistent cropping systems and fertilization.

    Science.gov (United States)

    Zhang, T Q; Tan, C S; Zheng, Z M; Drury, C F

    2015-03-01

    Phosphorus (P) loss in tile drainage water may vary with agricultural practices, and the impacts are often hard to detect with short-term studies. We evaluated the effects of long-term (≥43 yr) cropping systems (continuous corn [CC], corn-oats-alfalfa-alfalfa rotation [CR], and continuous grass [CS]) and fertilization (fertilization [F] vs. no-fertilization [NF]) on P loss in tile drainage water from a clay loam soil over a 4-yr period. Compared with NF, long-term fertilization increased concentrations and losses of dissolved reactive P (DRP), dissolved unreactive P (DURP), and total P (TP) in tile drainage water, with the increments following the order: CS > CR > CC. Dissolved P (dissolved reactive P [DRP] and dissolved unreactive P [DURP]) was the dominant P form in drainage outflow, accounting for 72% of TP loss under F-CS, whereas particulate P (PP) was the major form of TP loss under F-CC (72%), F-CR (62%), NF-CS (66%), NF-CC (74%), and NF-CR (72%). Dissolved unreactive P played nearly equal roles as DRP in P losses in tile drainage water. Stepwise regression analysis showed that the concentration of P (DRP, DURP, and PP) in tile drainage flow, rather than event flow volume, was the most important factor contributing to P loss in tile drainage water, although event flow volume was more important in PP loss than in dissolved P loss. Continuous grass significantly increased P loss by increasing P concentration and flow volume of tile drainage water, especially under the fertilization treatment. Long-term grasslands may become a significant P source in tile-drained systems when they receive regular P addition. Copyright © by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America, Inc.

  17. Network reconfiguration for loss reduction in electrical distribution system using genetic algorithm

    International Nuclear Information System (INIS)

    Adail, A.S.A.A.

    2012-01-01

    Distribution system is a critical links between the utility and the nuclear installation. During feeding electricity to that installation there are power losses. The quality of the network depends on the reduction of these losses. Distribution system which feeds the nuclear installation must have a higher quality power. For example, in Inshas site, electrical power is supplied to it from two incoming feeders (one from new abu-zabal substation and the other from old abu-zabal substation). Each feeder is designed to carry the full load, while the operator preferred to connect with a new abu-zabal substation, which has a good power quality. Bad power quality affects directly the nuclear reactor and has a negative impact on the installed sensitive equipment's of the operation. The thesis is Studying the electrical losses in a distribution system (causes and effected factors), feeder reconfiguration methods, and applying of genetic algorithm in an electric distribution power system. In the end, this study proposes an optimization technique based on genetic algorithms for distribution network reconfiguration to reduce the network losses to minimum. The proposed method is applied to IEEE test network; that contain 3 feeders and 16 nodes. The technique is applied through two groups, distribution have general loads, and nuclear loads. In the groups the technique applied to seven cases at normal operation state, system fault condition as well as different loads conditions. Simulated results are drawn to show the accuracy of the technique.

  18. A New Profile Learning Model for Recommendation System based on Machine Learning Technique

    Directory of Open Access Journals (Sweden)

    Shereen H. Ali

    2016-03-01

    Full Text Available Recommender systems (RSs have been used to successfully address the information overload problem by providing personalized and targeted recommendations to the end users. RSs are software tools and techniques providing suggestions for items to be of use to a user, hence, they typically apply techniques and methodologies from Data Mining. The main contribution of this paper is to introduce a new user profile learning model to promote the recommendation accuracy of vertical recommendation systems. The proposed profile learning model employs the vertical classifier that has been used in multi classification module of the Intelligent Adaptive Vertical Recommendation (IAVR system to discover the user’s area of interest, and then build the user’s profile accordingly. Experimental results have proven the effectiveness of the proposed profile learning model, which accordingly will promote the recommendation accuracy.

  19. Power loss problems in EXTRAP coil systems

    International Nuclear Information System (INIS)

    Lehnert, B.

    1977-02-01

    The Ohmic power loss in the coils of external ring traps is minimized with respect to the thermonuclear power production. In the case of the DT-reaction this leads to dimensions and power densities being relevant to full-scale reactors. Not only superconducting or refrigerated coil windings can thus be used, but also hot-coil systems which are operated at several hundred degrees centrigrade and form part of a steam cycle and power extraction system. For hot coils the problems of void formation and tritium regeneration have to be further examined. The high beta value leads to moderately large coil stresses. Finally, replacement and repair become simplified by the present coil geometry. (Auth.)

  20. The upgraded data acquisition system for beam loss monitoring at the Fermilab Tevatron and Main Injector

    International Nuclear Information System (INIS)

    Baumbaugh, A.; Briegel, C.; Brown, B.C.; Capista, D.; Drennan, C.; Fellenz, B.; Knickerbocker, K.; Lewis, J.D.; Marchionni, A.; Needles, C.; Olson, M.

    2011-01-01

    A VME-based data acquisition system for beam-loss monitors has been developed and is in use in the Tevatron and Main Injector accelerators at the Fermilab complex. The need for enhanced beam-loss protection when the Tevatron is operating in collider-mode was the main driving force for the new design. Prior to the implementation of the present system, the beam-loss monitor system was disabled during collider operation and protection of the Tevatron magnets relied on the quench protection system. The new Beam-Loss Monitor system allows appropriate abort logic and thresholds to be set over the full set of collider operating conditions. The system also records a history of beam-loss data prior to a beam-abort event for post-abort analysis. Installation of the Main Injector system occurred in the fall of 2006 and the Tevatron system in the summer of 2007. Both systems were fully operation by the summer of 2008. In this paper we report on the overall system design, provide a description of its normal operation, and show a number of examples of its use in both the Main Injector and Tevatron.

  1. Productivity Losses and Costs in the Less-Common Systemic Autoimmune Rheumatic Diseases.

    Science.gov (United States)

    McCormick, Natalie; Marra, Carlo A; Aviña-Zubieta, J Antonio

    2017-10-30

    We synthesised the literature on productivity losses and costs in the less-common systemic autoimmune rheumatic diseases: Sjogren's syndrome (SjS), systemic sclerosis (SSc), poly/dermatomyositis (PM/DM), and systemic vasculitides (SV). Of 29 studies located, 12 were published 2012 onwards (SSc = 6, SjS = 2, PM/DM = 2, SV = 2). In these, 25% of PM/DM, and 21-26% of SV, were work disabled, 22% of SSc stopped work within 3 years of diagnosis, and annual costs of absenteeism in SSc averaged $12,024 2017 USD. Very few studies reported on costs, presenteeism (working at reduced levels), or unpaid productivity loss. Across multiple systemic autoimmune rheumatic diseases (SARDs), major drivers of lost productivity were generalised items like pain, depression, and fatigue, rather than disease-specific factors. Evidence suggests that work disability is common in SSc and strikes quickly. However, in SSc and other SARDs, more comprehensive estimates are needed, which include absenteeism and presenteeism from paid and unpaid work, costs, and drivers of productivity loss.

  2. Monte Carlo simulation of single accident airport risk profile

    Science.gov (United States)

    1979-01-01

    A computer simulation model was developed for estimating the potential economic impacts of a carbon fiber release upon facilities within an 80 kilometer radius of a major airport. The model simulated the possible range of release conditions and the resulting dispersion of the carbon fibers. Each iteration of the model generated a specific release scenario, which would cause a specific amount of dollar loss to the surrounding community. By repeated iterations, a risk profile was generated, showing the probability distribution of losses from one accident. Using accident probability estimates, the risks profile for annual losses was derived. The mechanics are described of the simulation model, the required input data, and the risk profiles generated for the 26 large hub airports.

  3. Exact boundary controllability of nodal profile for quasilinear hyperbolic systems

    CERN Document Server

    Li, Tatsien; Gu, Qilong

    2016-01-01

    This book provides a comprehensive overview of the exact boundary controllability of nodal profile, a new kind of exact boundary controllability stimulated by some practical applications. This kind of controllability is useful in practice as it does not require any precisely given final state to be attained at a suitable time t=T by means of boundary controls, instead it requires the state to exactly fit any given demand (profile) on one or more nodes after a suitable time t=T by means of boundary controls. In this book we present a general discussion of this kind of controllability for general 1-D first order quasilinear hyperbolic systems and for general 1-D quasilinear wave equations on an interval as well as on a tree-like network using a modular-structure construtive method, suggested in LI Tatsien's monograph "Controllability and Observability for Quasilinear Hyperbolic Systems"(2010), and we establish a complete theory on the local exact boundary controllability of nodal profile for 1-D quasilinear hyp...

  4. A paper recommender system based on user's profile in big data ...

    African Journals Online (AJOL)

    These systems present a personalized proposal to users who seek to find a special kind of relevant data or their priorities through the big number of data. Recommendersystem based on personalization uses the user profile and in view of the fact that the user profile encompass information pertaining to the user priorities; ...

  5. On the Trade-off between Energy Consumption and Food Quality Loss in Supermarket Refrigeration Systems

    DEFF Research Database (Denmark)

    Cai, Junping; Jensen, Jørgen Bauck; Skogestad, Sigurd

    2008-01-01

    This paper studies the trade-off between energy consumption and food quality loss, at varying ambient conditions, in supermarket refrigeration systems. Compared with the traditional operation with pressure control, a large potential for energy savings without extra loss of food quality is demonst......This paper studies the trade-off between energy consumption and food quality loss, at varying ambient conditions, in supermarket refrigeration systems. Compared with the traditional operation with pressure control, a large potential for energy savings without extra loss of food quality...

  6. Diet-borne systemic inflammation is associated with prevalent tooth loss.

    Science.gov (United States)

    Kotsakis, Georgios A; Chrepa, Vanessa; Shivappa, Nitin; Wirth, Michael; Hébert, James; Koyanagi, Ai; Tyrovolas, Stefanos

    2017-06-09

    The deleterious effect of cariogenic dietary patterns on tooth loss is well characterized, but the contribution of diet-borne systemic inflammation to loss of teeth remains uncharted. Recent efforts have unveiled a protective role of single nutrients to periodontal health. However, the assessment of overall diet as a modifiable risk factor for oral health remains elusive. Thus, the aim of this study was to assess the association between diet-borne systemic inflammation and tooth loss in a representative sample of the US adult non-institutionalized population. A cross-sectional analysis of a sample of participants of the 2009-2010 and 2011-2012 continuous NHANES receiving an oral exam and providing dietary recall data was performed. Dietary inflammatory potential was assessed by the Dietary Inflammatory Index (DII), a composite measure computed based on the association between nutrients and systemic pro-inflammatory cytokine levels. The outcome measure was prevalent tooth loss. Numbers of missing teeth were regressed across quartiles of the DII using multivariable linear regression models. 6887 eligible NHANES participants were included in the analysis; participants in the highest quartile of the DII index (pro-inflammatory diet) had an average [95% CI] of 0.84 [0.24, 1.45] additional more teeth lost as compared to those in the lowest quartile of DII (anti-inflammatory diet) (p = 0.015), after adjusting for known confounders. This significant association remained in subgroup analyses, including the lowest tertiles of energy-adjusted carbohydrate intake, and in persons aged ≥50 years. Adherence to an anti-inflammatory diet is associated with fewer missing teeth. These results suggest protective dietary patterns as a modifiable protective factor for tooth loss in the US adult population and support the incorporation of tooth loss prevention in the agenda of dietary public health interventions to prevent chronic inflammatory diseases. Copyright © 2017 Elsevier Ltd

  7. Hamiltonian formulation of systems with balanced loss-gain and exactly solvable models

    Science.gov (United States)

    Ghosh, Pijush K.; Sinha, Debdeep

    2018-01-01

    A Hamiltonian formulation of generic many-body systems with balanced loss and gain is presented. It is shown that a Hamiltonian formulation is possible only if the balancing of loss and gain terms occurs in a pairwise fashion. It is also shown that with the choice of a suitable co-ordinate, the Hamiltonian can always be reformulated in the background of a pseudo-Euclidean metric. If the equations of motion of some of the well-known many-body systems like Calogero models are generalized to include balanced loss and gain, it appears that the same may not be amenable to a Hamiltonian formulation. A few exactly solvable systems with balanced loss and gain, along with a set of integrals of motion are constructed. The examples include a coupled chain of nonlinear oscillators and a many-particle Calogero-type model with four-body inverse square plus two-body pair-wise harmonic interactions. For the case of nonlinear oscillators, stable solution exists even if the loss and gain parameter has unbounded upper range. Further, the range of the parameter for which the stable solutions are obtained is independent of the total number of the oscillators. The set of coupled nonlinear equations are solved exactly for the case when the values of all the constants of motions except the Hamiltonian are equal to zero. Exact, analytical classical solutions are presented for all the examples considered.

  8. The upgraded ring loss radiation monitorinng system at the AGS

    International Nuclear Information System (INIS)

    Bennett, G.W.; Beadle, E.; Castille, V.; Witkover, R.L.

    1989-01-01

    With the Booster the AGS will accelerate protons to 3 /times/ 10 13 per cycle, polarized protons at 10 12 , and ions from Carbon to Gold at intensities from 50 to 3 /times/ 10 9 . A loss monitoring system is being developed to facilitate tuning, and to reduce personnel radiation exposure by minimizing residual induced activity and by allowing remote monitoring of activity in the accelerator enclosure. The monitoring system must have a large dynamic range to monitor high intensity beam losses and to measure induced activity down to the level of a few mrad/hour. Various detectors are being evaluated, including ion chambers, proportional counters, and aluminium cathode electronmultipliers. Measurements of the prompt ionization distribution in the median plane at various energies from point targets at two representative locations in the accelerator lattice have been completed. Details of the monitoring system will be presented, as well as the experimental measurements of the prompt radiation field, and a comparable Monte Carlo calculation. 2 refs., 5 figs

  9. Profiles of the Hα line by means of the analogical television system

    International Nuclear Information System (INIS)

    Andrillat, Y.; Fehrenbach, Ch.

    1981-01-01

    High resolution profiles of the Hα line are derived for about thirty Be stars and several bright stars by means of the analogical television system. The profiles obtained with this method fairly agree with the theoretical ones (α Lyrae). (Auth.)

  10. The LHC beam loss monitoring system's real-time data analysis card

    CERN Document Server

    Dehning, B; Ferioli, G; Guaglio, G; Leitner, R; Zamantzas, C

    2005-01-01

    The BLM (Beam Loss Monitoring) system has to prevent the superconducting magnets from being quenched and protect the machine components against damages making it one of the most critical elements for the protection of the LHC. The complete system consists of 3600 detectors, placed at various locations around the ring, tunnel electronics, which are responsible for acquiring, digitizing, and transmitting the data, and surface electronics, which receive the data via 2km optical data links, process, analyze, store, and issue warning and abort triggers. At those surface units, named BLMTCs, the backbone on each of them is an FPGA (field programmable gate array) which treats the loss signals collected from 16 detectors. It takes into account the beam energy and keeps 192 running sums giving loss durations of up to the last 84 seconds before it compares them with thresholds uniquely programmable for each detector. In this paper, the BLMTC's design is explored giving emphasis to the strategies followed in combining t...

  11. Advantages and Pitfalls of Mass Spectrometry Based Metabolome Profiling in Systems Biology

    Directory of Open Access Journals (Sweden)

    Ina Aretz

    2016-04-01

    Full Text Available Mass spectrometry-based metabolome profiling became the method of choice in systems biology approaches and aims to enhance biological understanding of complex biological systems. Genomics, transcriptomics, and proteomics are well established technologies and are commonly used by many scientists. In comparison, metabolomics is an emerging field and has not reached such high-throughput, routine and coverage than other omics technologies. Nevertheless, substantial improvements were achieved during the last years. Integrated data derived from multi-omics approaches will provide a deeper understanding of entire biological systems. Metabolome profiling is mainly hampered by its diversity, variation of metabolite concentration by several orders of magnitude and biological data interpretation. Thus, multiple approaches are required to cover most of the metabolites. No software tool is capable of comprehensively translating all the data into a biologically meaningful context yet. In this review, we discuss the advantages of metabolome profiling and main obstacles limiting progress in systems biology.

  12. Advantages and Pitfalls of Mass Spectrometry Based Metabolome Profiling in Systems Biology.

    Science.gov (United States)

    Aretz, Ina; Meierhofer, David

    2016-04-27

    Mass spectrometry-based metabolome profiling became the method of choice in systems biology approaches and aims to enhance biological understanding of complex biological systems. Genomics, transcriptomics, and proteomics are well established technologies and are commonly used by many scientists. In comparison, metabolomics is an emerging field and has not reached such high-throughput, routine and coverage than other omics technologies. Nevertheless, substantial improvements were achieved during the last years. Integrated data derived from multi-omics approaches will provide a deeper understanding of entire biological systems. Metabolome profiling is mainly hampered by its diversity, variation of metabolite concentration by several orders of magnitude and biological data interpretation. Thus, multiple approaches are required to cover most of the metabolites. No software tool is capable of comprehensively translating all the data into a biologically meaningful context yet. In this review, we discuss the advantages of metabolome profiling and main obstacles limiting progress in systems biology.

  13. Financial system loss as an example of high consequence, high frequency events

    Energy Technology Data Exchange (ETDEWEB)

    McGovern, D.E.

    1996-07-01

    Much work has been devoted to high consequence events with low frequency of occurrence. Characteristic of these events are bridge failure (such as that of the Tacoma Narrows), building failure (such as the collapse of a walkway at a Kansas City hotel), or compromise of a major chemical containment system (such as at Bhopal, India). Such events, although rare, have an extreme personal, societal, and financial impact. An interesting variation is demonstrated by financial losses due to fraud and abuse in the money management system. The impact can be huge, entailing very high aggregate costs, but these are a result of the contribution of many small attacks and not the result of a single (or few) massive events. Public awareness is raised through publicized events such as the junk bond fraud perpetrated by Milikin or gross mismanagement in the failure of the Barings Bank through unsupervised trading activities by Leeson in Singapore. These event,s although seemingly large (financial losses may be on the order of several billion dollars), are but small contributors to the estimated $114 billion loss to all types of financial fraud in 1993. This paper explores the magnitude of financial system losses and identifies new areas for analysis of high consequence events including the potential effect of malevolent intent.

  14. An appraisal profile of nostalgia.

    Science.gov (United States)

    van Tilburg, Wijnand A P; Bruder, Martin; Wildschut, Tim; Sedikides, Constantine; Göritz, Anja S

    2018-03-05

    The authors aimed to (a) identify the cognitive appraisals underlying nostalgia and (b) compare nostalgia with other emotions in terms of its appraisal profile. In Study 1, participants (N = 1,125) generated narratives. Next, they reported the level of nostalgia and 31 other emotions that these narratives elicited. Subsequently, participants evaluated the narrative events on several cognitive appraisals. Events that elicited nostalgia were pleasant, involved an irretrievable loss, felt psychologically distant, and were unique-an appraisal profile that differed from all other emotions. In Study 2 (N = 1,261), the authors experimentally varied these appraisals in a vignette paradigm and measured anticipated nostalgia and 10 other emotions. Participants anticipated most nostalgia when events were pleasant, involved irretrievable loss, were distant, and were unique-a profile shared only with longing. In Study 3 (N = 994), the authors used a guided autobiographical recall procedure in which they manipulated appraisals and measured the resultant emotions. Corroborating Studies 1-2, nostalgia was most intense for events that were pleasant, irretrievably lost, temporally distant, and unique. This appraisal profile was not shared by other emotions. The findings delineate the distinguishing cognitive appraisal profile of nostalgia. Nostalgia occupies a special place in the pantheon of emotions. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  15. Power Loss Calculation and Thermal Modelling for a Three Phase Inverter Drive System

    Directory of Open Access Journals (Sweden)

    Z. Zhou

    2005-12-01

    Full Text Available Power losses calculation and thermal modelling for a three-phase inverter power system is presented in this paper. Aiming a long real time thermal simulation, an accurate average power losses calculation based on PWM reconstruction technique is proposed. For carrying out the thermal simulation, a compact thermal model for a three-phase inverter power module is built. The thermal interference of adjacent heat sources is analysed using 3D thermal simulation. The proposed model can provide accurate power losses with a large simulation time-step and suitable for a long real time thermal simulation for a three phase inverter drive system for hybrid vehicle applications.

  16. Design and performance of the beam loss monitor system for the Advanced Photon Source

    International Nuclear Information System (INIS)

    Patterson, D.

    1994-01-01

    The design of the beam loss monitor system for the Argonne National Laboratory Advanced Photon Source is based on using a number of air dielectric coaxial cables as long ionization chambers. The coaxial cables are multiplexed into a high sensitivity DC current-to-voltage converter, which provides an output proportional to the average loss rate over the length of the multiplexed cable. Losses of sufficient amplitude generate measurable voltage pulses on the coaxial cable at a location near the loss point. Multiplexed pulse timing circuits determine the location of the losses by measuring the time at which these voltage pulses arrive at the beginning of the coaxial cable. The loss monitor system has been tested on the SPEAR accelerator at SSRL and was demonstrated to be as sensitive as the DCCT. Preliminary performance data from the APS injector show that the sensitivities of the current-to-voltage, converter circuit are about ten picoamperes of loss monitor signal per picocoulomb per second beam loss rate. The corresponding pulse sensitivity is about 28 μV pulse amplitude in the coaxial cable per picocoulomb of loss. Both these sensitivities are at 300-MeV beam energies. The loss monitor has proven useful in initial commissioning of the injector. Further data will be available as accelerator construction and commissioning continue

  17. Narrow power deposition profiles on the JET divertor target

    International Nuclear Information System (INIS)

    Lingertat, J.; Laux, M.; Monk, R.

    2001-01-01

    One of the key unresolved issues in the design of a future fusion reactor is the power handling capability of the divertor target plates. Earlier we reported on the existence of narrow power deposition profiles in JET, obtained mainly from Langmuir probe measurements. We repeated these measurements in the MkI, MkII and MkIIGB divertor configurations with an upgraded probe system, which allowed us to study the profile shape in more detail. The main results of this study are: In NB heated discharges the electron temperature and power flux at the outer target show a distinct peak of ∼5 mm half-width near the separatrix strike point. The corresponding profiles on the inner target do not show a similar feature. The height of the narrow peak increases with NB heating power and decreases with deuterium and impurity gas puffing. Ion orbit losses are suggested as a possible explanation of the observed profile shape

  18. Towards Malaysian LADM Country Profile for 2D and 3D Cadastral Registration System

    OpenAIRE

    Zulkifli, N.A.; Abdul Rahman, A.; Jamil, H.; Teng, C.H.; Tan, L.C.; Looi, K.S.; Chan, K.L.; Van Oosterom, P.J.M.

    2014-01-01

    This paper proposes a comprehensive Land Administration Domain Model (LADM, ISO 2012) country profile for 2D and 3D cadastral registration system for Malaysia. The proposed Malaysian country profile is partly based on the existing spatial (including survey) and administrative registration systems, and partly based on new developments inspired by the LADM standard. Within the country profile, an attempt is made to cover all Malaysian land administration related information, which are maintaine...

  19. Towards Malaysian LADM Country Profile for 2D and 3D Cadastral Registration System

    NARCIS (Netherlands)

    Zulkifli, N.A.; Abdul Rahman, A.; Jamil, H.; Teng, C.H.; Tan, L.C.; Looi, K.S.; Chan, K.L.; Van Oosterom, P.J.M.

    2014-01-01

    This paper proposes a comprehensive Land Administration Domain Model (LADM, ISO 2012) country profile for 2D and 3D cadastral registration system for Malaysia. The proposed Malaysian country profile is partly based on the existing spatial (including survey) and administrative registration systems,

  20. Towards a smart non-invasive fluid loss measurement system.

    Science.gov (United States)

    Suryadevara, N K; Mukhopadhyay, S C; Barrack, L

    2015-04-01

    In this article, a smart wireless sensing non-invasive system for estimating the amount of fluid loss, a person experiences while physical activity is presented. The system measures three external body parameters, Heart Rate, Galvanic Skin Response (GSR, or skin conductance), and Skin Temperature. These three parameters are entered into an empirically derived formula along with the user's body mass index, and estimation for the amount of fluid lost is determined. The core benefit of the developed system is the affluence usage in combining with smart home monitoring systems to care elderly people in ambient assisted living environments as well in automobiles to monitor the body parameters of a motorist.

  1. Stochastic ℋ∞ Finite-Time Control of Discrete-Time Systems with Packet Loss

    Directory of Open Access Journals (Sweden)

    Yingqi Zhang

    2012-01-01

    Full Text Available This paper investigates the stochastic finite-time stabilization and ℋ∞ control problem for one family of linear discrete-time systems over networks with packet loss, parametric uncertainties, and time-varying norm-bounded disturbance. Firstly, the dynamic model description studied is given, which, if the packet dropout is assumed to be a discrete-time homogenous Markov process, the class of discrete-time linear systems with packet loss can be regarded as Markovian jump systems. Based on Lyapunov function approach, sufficient conditions are established for the resulting closed-loop discrete-time system with Markovian jumps to be stochastic ℋ∞ finite-time boundedness and then state feedback controllers are designed to guarantee stochastic ℋ∞ finite-time stabilization of the class of stochastic systems. The stochastic ℋ∞ finite-time boundedness criteria can be tackled in the form of linear matrix inequalities with a fixed parameter. As an auxiliary result, we also give sufficient conditions on the robust stochastic stabilization of the class of linear systems with packet loss. Finally, simulation examples are presented to illustrate the validity of the developed scheme.

  2. World Energy Data System (WENDS). Volume VI. International agreement profiles

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-06-01

    The World Energy Data System contains organized data on those countries and international organizations that may have critical impact on world energy. The international agreement profiles in WENDS are all energy-related and are organized by energy technology. These are: coal; conservation; fusion; geothermal; nuclear fission; oil, gas, and shale; solar, wind, and ocean thermal; and other (cooperation in electrical power equipment acquisition, energy, energy research, etc.). The agreement profiles are accessible by energy technology and alphabetically by country.

  3. The Beam Profile Monitoring System for the CERN IRRAD Proton Facility

    CERN Document Server

    Ravotti, F; Glaser, M; Matli, E; Pezzullo, G; Gan, K K; Kagan, H; Smith, S; Warner, J D

    2017-01-01

    GeV/c proton beam is used. During beam steering and irradiation, the intensity and the transverse profile of the proton beam are monitored online with custom-made Beam Profile Monitor (BPM) devices. In this work, we present the design and the architecture of the IRRAD BPM system, some results on its performance with the proton beam, as well as its planned grades.

  4. Mass loss from interacting close binary systems

    Science.gov (United States)

    Plavec, M. J.

    1981-01-01

    The three well-defined classes of evolved binary systems that show evidence of present and/or past mass loss are the cataclysmic variables, the Algols, and Wolf-Rayet stars. It is thought that the transformation of supergiant binary systems into the very short-period cataclysmic variables must have been a complex process. The new evidence that has recently been obtained from the far ultraviolet spectra that a certain subclass of the Algols (the Serpentids) are undergoing fairly rapid evolution is discussed. It is thought probable that the remarkable mass outflow observed in them is connected with a strong wind powered by accretion. The origin of the circumbinary clouds or flat disks that probably surround many strongly interacting binaries is not clear. Attention is also given to binary systems with hot white dwarf or subdwarf components, such as the symbiotic objects and the BQ stars; it is noted that in them both components may be prone to an enhanced stellar wind.

  5. Analysis of losses within SMES system for compensating output fluctuation of wind power farm

    Energy Technology Data Exchange (ETDEWEB)

    Park, S. I.; Kim, J. H.; Le, T. D.; Lee, D. H.; Kim, H. M. [Jeju National University, Jeju (Korea, Republic of); Yoon, Y. S. [Dept. of Electrical Engineering, Shin Ansan University, Ansan (Korea, Republic of); Yoon, K. Y. [Dept. of lectrical and Electronic Engineering, Yonsei University, Seoul (Korea, Republic of)

    2014-12-15

    Output fluctuation which is generated in wind power farm can hinder stability of total power system. The electric energy storage (EES) reduces unstable output, and superconducting magnetic energy storage (SMES) of various EESs has the proper performance for output compensation of wind power farm since it charges and discharges large scale power quickly with high efficiency. However, because of the change of current within SMES, the electromagnetic losses occur in the process of output compensation. In this paper, the thermal effect of the losses that occur in SMES system while compensating in wind power farm is analyzed. The output analysis of wind power farm is processed by numerical analysis, and the losses of SMES system is analyzed by 3D finite element analysis (FEA) simulation tool.

  6. Analysis of losses within SMES system for compensating output fluctuation of wind power farm

    International Nuclear Information System (INIS)

    Park, S. I.; Kim, J. H.; Le, T. D.; Lee, D. H.; Kim, H. M.; Yoon, Y. S.; Yoon, K. Y.

    2014-01-01

    Output fluctuation which is generated in wind power farm can hinder stability of total power system. The electric energy storage (EES) reduces unstable output, and superconducting magnetic energy storage (SMES) of various EESs has the proper performance for output compensation of wind power farm since it charges and discharges large scale power quickly with high efficiency. However, because of the change of current within SMES, the electromagnetic losses occur in the process of output compensation. In this paper, the thermal effect of the losses that occur in SMES system while compensating in wind power farm is analyzed. The output analysis of wind power farm is processed by numerical analysis, and the losses of SMES system is analyzed by 3D finite element analysis (FEA) simulation tool.

  7. Real Mission Profile Based Lifetime Estimation of Fuel-cell Power Converter

    DEFF Research Database (Denmark)

    Zhou, Dao; Wang, Huai; Blaabjerg, Frede

    2016-01-01

    . This paper describes a lifetime prediction method for the power semiconductors used in the power conditioning of a fuel cell based backup system, considering both the long-term standby mode and active operation mode. The annual ambient temperature profile is taken into account to estimate its impact...... on the degradation of MOSFETs during the standby mode. At the presence of power outages, the backup system is activated into the operation mode and the MOSFETs withstand additional thermal stresses due to power losses. A study case of a 1 kW backup system is presented with two annual mission profiles in Denmark...... and India, respectively. The ambient temperature, occurrence frequency of power outages, active operation time and power levels are considered for the lifetime prediction of the applied MOSFETs. Comparisons of the accumulated lifetime consumptions are performed between standby mode and operation mode...

  8. Experimental and numerical investigations of microwave return loss of aircraft inlets with low-pressure plasma

    Science.gov (United States)

    Zhang, Yachun; He, Xiang; Chen, Jianping; Chen, Hongqing; Chen, Li; Zhang, Hongchao; Ni, Xiaowu; Lu, Jian; Shen, Zhonghua

    2018-03-01

    The relationships between return losses of the cylindrical inlet and plasma discharge parameters are investigated experimentally and numerically. The return losses are measured using a high dynamic range measurement system and simulated by COMSOL Multiphysics when the frequency band of the microwaves is in the range 1-4 GHz. The profiles of the plasma density are estimated using Epstein and Bessel functions. Results show that the incident microwaves can be absorbed by plasma efficaciously. The maximal return loss can reach -13.84 dB when the microwave frequency is 2.3 GHz. The increase of applied power implies augmentation of the return loss, which behaves conversely for gas pressure. The experimental and numerical results display reasonable agreement on return loss, suggesting that the use of plasma is effective in the radar cross section reduction of aircraft inlets.

  9. The LEP RF Trip and Beam Loss Diagnostics System

    CERN Document Server

    Arnaudon, L; Beetham, G; Ciapala, Edmond; Juillard, J C; Olsen, R

    2002-01-01

    During the last years of operation the number of operationally independent RF stations distributed around LEP reached a total of 40. A serious difficulty when running at high energy and high beam intensities was to establish cause and effect in beam loss situations, where the trip of any single RF station would result in beam loss, rapidly producing further multiple RF station trips. For the last year of operation a fast post-mortem diagnostics system was developed to allow precise time-stamping of RF unit trips and beam intensity changes. The system was based on eight local DSP controlled fast acquisition and event recording units, one in each RF sector, connected to critical RF control signals and fast beam intensity monitors and synchronised by GPS. The acquisition units were armed and synchronised at the start of each fill. At the end of the fill the local time-stamped RF trip and beam intensity change history tables were recovered, events ordered and the results stored in a database for subsequent analys...

  10. Image processing and computer controls for video profile diagnostic system in the ground test accelerator (GTA)

    International Nuclear Information System (INIS)

    Wright, R.; Zander, M.; Brown, S.; Sandoval, D.; Gilpatrick, D.; Gibson, H.

    1992-01-01

    This paper describes the application of video image processing to beam profile measurements on the Ground Test Accelerator (GTA). A diagnostic was needed to measure beam profiles in the intermediate matching section (IMS) between the radio-frequency quadrupole (RFQ) and the drift tube linac (DTL). Beam profiles are measured by injecting puffs of gas into the beam. The light emitted from the beam-gas interaction is captured and processed by a video image processing system, generating the beam profile data. A general purpose, modular and flexible video image processing system, imagetool, was used for the GTA image profile measurement. The development of both software and hardware for imagetool and its integration with the GTA control system (GTACS) is discussed. The software includes specialized algorithms for analyzing data and calibrating the system. The underlying design philosophy of imagetool was tested by the experience of building and using the system, pointing the way for future improvements. (Author) (3 figs., 4 refs.)

  11. Analisa Perbaikan Profil Tegangan Sistem Tenaga Listrik Sumbar Menggunakan Kapasitor Bank dan Tap Transformator

    Directory of Open Access Journals (Sweden)

    Akbar Abadi

    2015-09-01

    Full Text Available Voltage stability evaluation is needed to get the information of electrical power distribution system performance. Power flow calculation is used to determine the important parameters of power system in a steady state. An electric power system must have voltage value that does not exceed the limits of tolerance and the power loss as well as small. The improvement of voltage profile can be done by using voltage-control equipments, such as capacitor banks and transformer tap. Through simulation using the PowerWorld simulator, the value and location of capacitor banks and transformers tap will obtained in order to improve system performace. Sumbar electrical system was used in this study. From the simulation results, for the initial condition of the system, there are several buses that have voltage drop with total system losses 14.4 MW. After capacitor added, the system voltage has increased significantly so that no one passed the value of tolerance and the losses in the system down to 14.1 MW. As for setting the ratio of tap transformer, voltage system did not change so much, except on the secondary side of the transformer bus arranged with system losses almost the same that equal to 14.4 MW. For the case of the addition of the capacitor and transformer tap settings in the same time, the voltage drop no longer exceeds 5% and the total system losses decreased to 13.9 MW.

  12. Power profiling of Cholesky and QR factorizations on distributed memory systems

    KAUST Repository

    Bosilca, George; Ltaief, Hatem; Dongarra, Jack

    2012-01-01

    with a dynamic distributed scheduler (DAGuE) to leverage distributed memory systems. We present performance results (Gflop/s) as well as the power profile (Watts) of two common dense factorizations needed to solve linear systems of equations, namely

  13. Dispersion-tailored, low-loss photonic crystal fibers for the THz range

    DEFF Research Database (Denmark)

    Nielsen, Kristian; Rasmussen, Henrik K.; Adam, Aurèle J.L.

    2009-01-01

    We have fabricated a new type of photonic crystal fibers based on a cyclic olefin copolymer, transparent in the THz range. We characterize the propagation loss, dispersion, and spatial beam profile in fibers designed for low and high dispersion.......We have fabricated a new type of photonic crystal fibers based on a cyclic olefin copolymer, transparent in the THz range. We characterize the propagation loss, dispersion, and spatial beam profile in fibers designed for low and high dispersion....

  14. Analysis of Mesh Distribution Systems Considering Load Models and Load Growth Impact with Loops on System Performance

    Science.gov (United States)

    Kumar Sharma, A.; Murty, V. V. S. N.

    2014-12-01

    The distribution system is the final link between bulk power system and consumer end. A distinctive load flow solution method is used for analysis of the load flow of radial and weakly meshed network based on Kirchhoff's Current Law (KCL) and KVL. This method has excellent convergence characteristics for both radial as well as weakly meshed structure and is based on bus injection to branch current and branch-current to bus-voltage matrix. The main contribution of the paper is: (i) an analysis has been carried out for a weekly mesh network considering number of loops addition and its impact on the losses, kW and kVAr requirements from a system, and voltage profile, (ii) different load models, realistic ZIP load model and load growth impact on losses, voltage profile, kVA and kVAr requirements, (iii) impact of addition of loops on losses, voltage profile, kVA and kVAr requirements from substation, and (iv) comparison of system performance with radial distribution system. Voltage stability is a major concern in planning and operation of power systems. This paper also includes identifying the closeness critical bus which is the most sensitive to the voltage collapse in radial distribution networks. Node having minimum value of voltage stability index is the most sensitive node. Voltage stability index values are computed for meshed network with number of loops added in the system. The results have been obtained for IEEE 33 and 69 bus test system. The results have also been obtained for radial distribution system for comparison.

  15. Toroidal equilibrium and radial profiles from magnetic measurements in Extrap T1

    International Nuclear Information System (INIS)

    Brunsell, Per; Jin Li; Tennfors, Einar

    1991-01-01

    The toroidal equilibrium position in the Extrap T1 toroidal Z-pinch is studied by measuring the currents induced in the external octupole field rings. Radial profiles are obtained by an internal magnetic coil array. From the magnetic field, profiles of current density, plasma pressure, safety factor, resistivity and input power density are deduced. A polynomial model is developed to simulate the measured profiles. The classical ion heat conduction losses in Extrap discharges are calculated using this model and compared to the power input. for polynomials matched to magnetic field profiles measured in present experiments, these losses are small. By varying the coefficients of the polynomials, a region is found where the power input can balance the classical heat conduction losses at higher values of Θ and β o . (Author)

  16. Delta flow: An accurate, reliable system for detecting kicks and loss of circulation during drilling

    Energy Technology Data Exchange (ETDEWEB)

    Speers, J.M.; Gehrig, G.F.

    1987-12-01

    A system to monitor drilling-fluid flow rate has been developed that detects kicks and lost returns in floating, fixed-platform, and land-base drilling operations. The system uses flowmeters that monitor the flow rates of drilling fluids entering the borehole through the standpipe and leaving the well through the return flowline. These readings are processed in a computer-based, data-acquisition system to form a filtered delta-flow signal that identified the occurrence of downhole fluid gains or losses. The system is designed to trip an alarm when a gain or loss exceeds 25 gal/min (1.6 dm/sup 3//s), even in a floating drilling environment. This sensitivity will generally keep gains or losses to less than 5 bbl (0.8 m/sup 3/).

  17. System Losses Study - FIT (Fuel-cycle Integration and Tradeoffs)

    Energy Technology Data Exchange (ETDEWEB)

    Steven J. Piet; Nick R. Soelberg; Samuel E. Bays; Robert S. Cherry; Denia Djokic; Candido Pereira; Layne F. Pincock; Eric L. Shaber; Melissa C. Teague; Gregory M. Teske; Kurt G. Vedros

    2010-09-01

    This team aimed to understand the broad implications of changes of operating performance and parameters of a fuel cycle component on the entire system. In particular, this report documents the study of the impact of changing the loss of fission products into recycled fuel and the loss of actinides into waste. When the effort started in spring 2009, an over-simplified statement of the objective was “the number of nines” – how would the cost of separation, fuel fabrication, and waste management change as the number of nines of separation efficiency changed. The intent was to determine the optimum “losses” of TRU into waste for the single system that had been the focus of the Global Nuclear Energy Program (GNEP), namely sustained recycle in burner fast reactors, fed by transuranic (TRU) material recovered from used LWR UOX-51 fuel. That objective proved to be neither possible (insufficient details or attention to the former GNEP options, change in national waste management strategy from a Yucca Mountain focus) nor appropriate given the 2009-2010 change to a science-based program considering a wider range of options. Indeed, the definition of “losses” itself changed from the loss of TRU into waste to a generic definition that a “loss” is any material that ends up where it is undesired. All streams from either separation or fuel fabrication are products; fuel feed streams must lead to fuels with tolerable impurities and waste streams must meet waste acceptance criteria (WAC) for one or more disposal sites. And, these losses are linked in the sense that as the loss of TRU into waste is reduced, often the loss or carryover of waste into TRU or uranium is increased. The effort has provided a mechanism for connecting these three Campaigns at a technical level that had not previously occurred – asking smarter and smarter questions, sometimes answering them, discussing assumptions, identifying R&D needs, and gaining new insights. The FIT model has been a

  18. Hair Loss Following The Topiramate Treatment

    Directory of Open Access Journals (Sweden)

    I Ghafoor

    2017-02-01

    Full Text Available BACKGROUND AND OBJECTIVE: Genetics, hormone profiles and other physiologic factors can cause hair loss. Medication induced hair loss is an occasional side effect of many psychopharmaceuticals. It can reduce medication compliance if not discovered and treated. We present a 18 year old female with migraine headache who developed hair loss after 3 months of receiving topiramate treatment. CASE REPORT: 18 year old female had been suffering from headache visited in psychiatric clinic. She agreed to a treatment with topiramate (50mg per day for Migraine headache. 3 months later, the patient complained of significant hair loss. Topiramate tapered to 25 mg/day and stopped. Hair loss stopped after topiramate withdrawal. Two weeks after reintroduction of topiramate, hair loss developed again. The medication was stopped and hair loss stopped again. CONCLUSION: Topiramate can cause hair loss. Although the condition is not life-threatening, a decrease in medication compliance can cause recurrence of the underlying disease. It is necessary to ask the patient at visits about it.

  19. Transmission Loss Calculation using A and B Loss Coefficients in Dynamic Economic Dispatch Problem

    Science.gov (United States)

    Jethmalani, C. H. Ram; Dumpa, Poornima; Simon, Sishaj P.; Sundareswaran, K.

    2016-04-01

    This paper analyzes the performance of A-loss coefficients while evaluating transmission losses in a Dynamic Economic Dispatch (DED) Problem. The performance analysis is carried out by comparing the losses computed using nominal A loss coefficients and nominal B loss coefficients in reference with load flow solution obtained by standard Newton-Raphson (NR) method. Density based clustering method based on connected regions with sufficiently high density (DBSCAN) is employed in identifying the best regions of A and B loss coefficients. Based on the results obtained through cluster analysis, a novel approach in improving the accuracy of network loss calculation is proposed. Here, based on the change in per unit load values between the load intervals, loss coefficients are updated for calculating the transmission losses. The proposed algorithm is tested and validated on IEEE 6 bus system, IEEE 14 bus, system IEEE 30 bus system and IEEE 118 bus system. All simulations are carried out using SCILAB 5.4 (www.scilab.org) which is an open source software.

  20. MEASUREMENT AND ANALYSIS OF TRANSMISSION LOSSES IN THE SUPPLY SYSTEM OF ELECTRIFIED TRANSPORT

    Directory of Open Access Journals (Sweden)

    Mikołaj Bartłomiejczyk

    2016-11-01

    Full Text Available The issue of electric energy saving in public transport is currently becoming a key area of interest, a fact connected with both an increase in society’s environmental awareness and a rise in the prices of fuel and electricity. Electricity can be saved by reducing transmission losses in the supply system. The article presents a method of measurement and analysis of transmission losses in the supply system of electrified public transport on the example of trolleybus transport in Gdynia and Lublin in Poland.

  1. Loss Allocation in a Distribution System with Distributed Generation Units

    DEFF Research Database (Denmark)

    Lund, Torsten; Nielsen, Arne Hejde; Sørensen, Poul Ejnar

    2007-01-01

    In Denmark, a large part of the electricity is produced by wind turbines and combined heat and power plants (CHPs). Most of them are connected to the network through distribution systems. This paper presents a new algorithm for allocation of the losses in a distribution system with distributed...... generation. The algorithm is based on a reduced impedance matrix of the network and current injections from loads and production units. With the algorithm, the effect of the covariance between production and consumption can be evaluated. To verify the theoretical results, a model of the distribution system...

  2. Evolution of Edge Pedestal Profiles Between ELMs

    Science.gov (United States)

    Floyd, J. P.; Stacey, W. M.; Groebner, R. J.

    2012-10-01

    The measured edge profile evolution in DIII-D discharges is analyzed in terms of the implied thermal diffusivities, ion diffusion coefficients and pinch velocities, using the momentum-balance methodology of Ref. [1], extended to take into account ion orbit loss and X-point loss. The evolution of the density, temperature, rotation and radial electric field profiles in the edge pedestal between edge localized modes (ELMs) provides information of these diffusive and non-diffusive transport processes in the pedestal of H-mode plasmas. This methodology is incorporated in the GTEDGE code developed for DIII-D data interpretation. Using a smaller integration time for the charge exchange recombination measurements than in Ref. [1] allows a more detailed examination of the time evolution of the ion temperature and rotation profiles. 6pt [1] W.M. Stacey and R.J. Groebner, Nucl. Fusion 51, 063024 (2011).

  3. Profile-IQ: Web-based data query system for local health department infrastructure and activities.

    Science.gov (United States)

    Shah, Gulzar H; Leep, Carolyn J; Alexander, Dayna

    2014-01-01

    To demonstrate the use of National Association of County & City Health Officials' Profile-IQ, a Web-based data query system, and how policy makers, researchers, the general public, and public health professionals can use the system to generate descriptive statistics on local health departments. This article is a descriptive account of an important health informatics tool based on information from the project charter for Profile-IQ and the authors' experience and knowledge in design and use of this query system. Profile-IQ is a Web-based data query system that is based on open-source software: MySQL 5.5, Google Web Toolkit 2.2.0, Apache Commons Math library, Google Chart API, and Tomcat 6.0 Web server deployed on an Amazon EC2 server. It supports dynamic queries of National Profile of Local Health Departments data on local health department finances, workforce, and activities. Profile-IQ's customizable queries provide a variety of statistics not available in published reports and support the growing information needs of users who do not wish to work directly with data files for lack of staff skills or time, or to avoid a data use agreement. Profile-IQ also meets the growing demand of public health practitioners and policy makers for data to support quality improvement, community health assessment, and other processes associated with voluntary public health accreditation. It represents a step forward in the recent health informatics movement of data liberation and use of open source information technology solutions to promote public health.

  4. Isolating the atmospheric circulation response to Arctic sea-ice loss in the coupled climate system

    Science.gov (United States)

    Kushner, Paul; Blackport, Russell

    2017-04-01

    In the coupled climate system, projected global warming drives extensive sea-ice loss, but sea-ice loss drives warming that amplifies and can be confounded with the global warming process. This makes it challenging to cleanly attribute the atmospheric circulation response to sea-ice loss within coupled earth-system model (ESM) simulations of greenhouse warming. In this study, many centuries of output from coupled ocean/atmosphere/land/sea-ice ESM simulations driven separately by sea-ice albedo reduction and by projected greenhouse-dominated radiative forcing are combined to cleanly isolate the hemispheric scale response of the circulation to sea-ice loss. To isolate the sea-ice loss signal, a pattern scaling approach is proposed in which the local multidecadal mean atmospheric response is assumed to be separately proportional to the total sea-ice loss and to the total low latitude ocean surface warming. The proposed approach estimates the response to Arctic sea-ice loss with low latitude ocean temperatures fixed and vice versa. The sea-ice response includes a high northern latitude easterly zonal wind response, an equatorward shift of the eddy driven jet, a weakening of the stratospheric polar vortex, an anticyclonic sea level pressure anomaly over coastal Eurasia, a cyclonic sea level pressure anomaly over the North Pacific, and increased wintertime precipitation over the west coast of North America. Many of these responses are opposed by the response to low-latitude surface warming with sea ice fixed. However, both sea-ice loss and low latitude surface warming act in concert to reduce storm track strength throughout the mid and high latitudes. The responses are similar in two related versions of the National Center for Atmospheric Research earth system models, apart from the stratospheric polar vortex response. Evidence is presented that internal variability can easily contaminate the estimates if not enough independent climate states are used to construct them

  5. Effect of ensiling process of total mixed ration on fermentation profile, nutrient loss and in situ ruminal degradation characteristics of diet.

    Science.gov (United States)

    Miyaji, Makoto; Matsuyama, Hiroki; Nonaka, Kazuhisa

    2017-01-01

    This experiment aimed to determine the changes in chemical composition, fermentation profile, in situ disappearance characteristics, and nutrient losses of ensiled total mixed ration (TMR) containing steam-flaked corn or brown rice (BR) during storage. TMRs for dairy cows, containing either steam-flaked corn or BR at 31.9% with 15.2% rye silage, 40.5% alfalfa silage, 5.0% beet pulp and 7.0% soybean meal, were prepared (dry matter (DM) basis). Each TMR was placed in a plastic drum silo, stored at 23°C in an air-conditioned room and sampled 0, 7, 14, 30, 90 and 210 days after preparation. In both grain sources, the fermentation products increased, while DM and starch storage losses increased and starch content greatly decreased during storage. The rapidly degradable fraction and effective ruminal degradability of DM, crude protein and starch increased during storage. These changes of dietary characteristics were large during 30 days of storage, but small after 90 days of storage. Replacing corn with BR led to increased fermentation products, starch loss and effective ruminal degradability of the ensiled TMR. These results indicate that the ensiling process of TMR changes the dietary characteristics and replacing corn with BR in TMR had a large impact on these dietary characteristics. © 2016 Japanese Society of Animal Science.

  6. Massive weight loss restores 24-hour growth hormone release profiles and serum insulin-like growth factor-I levels in obese subjects

    DEFF Research Database (Denmark)

    Rasmussen, M H; Hvidberg, A; Juul, A

    1995-01-01

    levels of insulin-like growth factor-I (IGF-I), IGF-binding protein-3 (IGFBP-3), as well as insulin in obese subjects before and after a massive weight loss. We studied 18 obese subjects (age, 26 +/- 1 yr; body mass index, 40.9 +/- 1.1 kg/m2); 18 normal age-, and sex-matched control subjects; and 9...... using anthropometric measurements and dual energy x-ray absorptiometry scanning (DXA). In the obese subjects, 24-h spontaneous GH release profiles and the GH responses to insulin-induced hypoglycemia and L-arginine as well as basal IGF-I levels and the IGF-I/IGFBP-3 molar ratio were decreased, whereas...

  7. Environmental Profile of the Swiss Supply Chain for French Fries: Effects of Food Loss Reduction, Loss Treatments and Process Modifications

    Directory of Open Access Journals (Sweden)

    Patrik Mouron

    2016-11-01

    Full Text Available The production of food is responsible for major environmental impacts. Bearing this in mind, it is even worse when food is lost rather than consumed. In Switzerland, 46% of all processing potatoes and 53% of all fresh potatoes are lost on their way from field to fork. Our study therefore compares the environmental impacts of losses of fresh potatoes with those of French fries. With the aid of a Life Cycle Assessment, we assessed the impact categories “demand for nonrenewable energy resources”, “global warming potential”, “human toxicity”, “terrestrial ecotoxicity” and “aquatic ecotoxicity”. Our results show that 1 kg of potatoes consumed as French fries causes 3–5 times more environmental impacts than the same quantity of fresh potatoes, but also that the proportion of impacts relating to losses is considerably lower for French fries (5%–10% vs. 23%–39%. The great majority of processing potato losses occur before the resource-intensive, emission-rich frying processes and therefore the environmental “backpack” carried by each lost potato is still relatively small. Nonetheless, appropriate loss treatment can substantially reduce the environmental impact of potato losses. In the case of French fries, the frying processes and frying oil are the main “hot spots” of environmental impacts, accounting for a considerably higher proportion of damage than potato losses; it is therefore also useful to look at these processes.

  8. Frequency dependent loss analysis and minimization of system losses in switchmode audio power amplifiers

    DEFF Research Database (Denmark)

    Yamauchi, Akira; Knott, Arnold; Jørgensen, Ivan Harald Holger

    2014-01-01

    In this paper, frequency dependent losses in switch-mode audio power amplifiers are analyzed and a loss model is improved by taking the voltage dependence of the parasitic capacitance of MOSFETs into account. The estimated power losses are compared to the measurement and great accuracy is achieved...

  9. Stabilization of breathers in a parametrically driven sine-Gordon system with loss

    DEFF Research Database (Denmark)

    Grønbech-Jensen, N.; Kivshar, Yu. S.; Samuelsen, Mogens Rugholm

    1991-01-01

    We demonstrate that in a parametrically driven sine-Gordon system with loss, a breather, if driven, can be maintained in a steady state at half the external frequency. In the small-amplitude limit the system is described by the effective perturbed nonlinear Schrödinger equation. For an arbitrary...

  10. In vitro steroid profiling system for the evaluation of endocrine disruptors.

    Science.gov (United States)

    Nakano, Yosuke; Yamashita, Toshiyuki; Okuno, Masashi; Fukusaki, Eiichiro; Bamba, Takeshi

    2016-09-01

    Endocrine disruptors (ED) are chemicals that affect various aspects of the endocrine system, often leading to the inhibition of steroidogenesis. Current chemical safety policies that restrict human exposure to such chemicals describe often time-consuming and costly methods for the evaluation of ED effects. We aimed to develop an effective tool for accurate phenotypic chemical toxicology studies. We developed an in vitro ED evaluation system using gas chromatography/mass spectrometry (GC/MS/MS) methods for metabolomic analysis of multi-marker profiles. Accounting for sample preparation and GC/MS/MS conditions, we established a screening method that allowed the simultaneous analysis of 17 steroids with good reproducibility and a linear calibration curve. Moreover, we applied the developed system to H295R human adrenocortical cells exposed to forskolin and prochloraz in accordance with the Organization for Economic Cooperation and Development (OECD) guidelines and observed dose-dependent variations in steroid profiles. While the OECD guidelines include only testosterone and 17β-estradiol, our system enabled a comprehensive and highly sensitive analysis of steroid profile alteration due to ED exposure. The application of our ED evaluation screen could be economical and provide novel insights into the hazards of ED exposure to the endocrine system. Copyright © 2016 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

  11. Event-Driven Control for Networked Control Systems With Quantization and Markov Packet Losses.

    Science.gov (United States)

    Yang, Hongjiu; Xu, Yang; Zhang, Jinhui

    2016-05-23

    In this paper, event-driven is used in a networked control system (NCS) which is subjected to the effect of quantization and packet losses. A discrete event-detector is used to monitor specific events in the NCS. Both an arbitrary region quantizer and Markov jump packet losses are also considered for the NCS. Based on zoom strategy and Lyapunov theory, a complete proof is given to guarantee mean square stability of the closed-loop system. Stabilization of the NCS is ensured by designing a feedback controller. Lastly, an inverted pendulum model is given to show the advantages and effectiveness of the proposed results.

  12. Loss of renal function causes premature aging of the immune system.

    Science.gov (United States)

    Betjes, Michiel G H; Meijers, Ruud W J; Litjens, Nicolle H R

    2013-01-01

    Uremia-associated immune deficiency is a well-known complication of loss of renal function and contributes significantly to the overall mortality and morbidity of patients with end-stage renal disease. Chronic inflammation and increased oxidative stress are underlying the uremia-associated immune deficiency. In this review, the differential impact of uremia on the cellular immune system is summarized. Virtually all immune cells studied show a combination of an activated status and loss of function. However, uremia preferentially decreases the number and function of lymphoid cells while myeloid cells show normal and/or elevated cell numbers with increased production of inflammatory cytokines and reactive oxygen species. These particular changes are compatible with immunological aging, which is characterized by loss of thymic function, attrition of telomeres and an expanded memory T cell population. Similar to aging in healthy individuals, the proinflammatory and potential cardiotoxic subsets of CD28(null) T cells and CD16(+) monocytes are increased. Epigenetically changed hematopoietic stem cells may be involved in immunological aging as specific DNA regions become hypermethylated. Proinflammatory T cells and monocytes persist after kidney transplantation, which constitutes a persistent cardiovascular risk factor. Possible therapeutic options to reverse or halt uremia-associated immunological aging are discussed. Premature aging of the immune system is a dominant feature in patients with end-stage renal failure, which corresponds to immunological aging in elderly healthy individuals, which is characterized by preferential loss of cells belonging to the lymphoid cell lineage, inflammation and expansion of proinflammatory immune cells. © 2013 S. Karger AG, Basel.

  13. A measurement system for vertical seawater profiles close to the air-sea interface

    Science.gov (United States)

    Sims, Richard P.; Schuster, Ute; Watson, Andrew J.; Yang, Ming Xi; Hopkins, Frances E.; Stephens, John; Bell, Thomas G.

    2017-09-01

    This paper describes a near-surface ocean profiler, which has been designed to precisely measure vertical gradients in the top 10 m of the ocean. Variations in the depth of seawater collection are minimized when using the profiler compared to conventional CTD/rosette deployments. The profiler consists of a remotely operated winch mounted on a tethered yet free-floating buoy, which is used to raise and lower a small frame housing sensors and inlet tubing. Seawater at the inlet depth is pumped back to the ship for analysis. The profiler can be used to make continuous vertical profiles or to target a series of discrete depths. The profiler has been successfully deployed during wind speeds up to 10 m s-1 and significant wave heights up to 2 m. We demonstrate the potential of the profiler by presenting measured vertical profiles of the trace gases carbon dioxide and dimethylsulfide. Trace gas measurements use an efficient microporous membrane equilibrator to minimize the system response time. The example profiles show vertical gradients in the upper 5 m for temperature, carbon dioxide and dimethylsulfide of 0.15 °C, 4 µatm and 0.4 nM respectively.

  14. Anomalous waves propagating at very high frequency in the atmosphere and their disturbances due to changes in refractivity profiles

    Science.gov (United States)

    Alam, Imtiaz; Waqar, Asad; Aamir, Muhammad; Hassan, Shahzad; Shah, Syed Asim Ali

    2018-03-01

    Anomalous waves propagation is severely affected due to almost always present variations in refractivity under various environmental conditions at different time, location and frequency. These conditions, representing different state of the atmosphere including e.g. foggy, rainy and cloudy etc., not only degrade the quality of the signal but sometimes completely eradicate the communication link. Such severe impact on propagation cannot be ignored by the designers of communication systems. The aim of this research is to present correlation between experimental and modelled link losses for variations in refractivity values recommended by International Telecommunication Union-Recommendations (ITU-R) as well as that of standard profiles. To do so, a communication setup of 50 km over the Sea operating experimentally over a period of a year at 240 MHz is analyzed for different refractivity profiles and their impact on propagation. A median value is taken for every set of 6000 values taken from the recorded data set of more than 48 million experimental link losses. This reduces the huge data set of the experimental link losses to 8000 values only. This reduced data set of experimental and modelled link losses were correlated and investigated for different evaporation duct heights throughout the year. For the considered link, the ITU-R refractivity profile was found to perform better than the standard refractivity profile. However, the new findings as observed in this research, which may be helpful for the recommendations authorities, is the existing of evaporation duct up to 10 m height.

  15. Resolution of methylphenidate osmotic release oral system-induced hair loss in two siblings after dose escalation.

    Science.gov (United States)

    Ardic, Ulku Akyol; Ercan, Eyup Sabri

    2017-11-01

    This report describes the cases of two siblings who experienced hair loss after treatment with methylphenidate (MPH) osmotic release oral system (OROS). Hair loss was resolved after discontinuation of the drug, but the children re-initiated treatment, after which hair loss again occurred, but they continued the treatment. After dose escalation, the hair loss resolved. This is the first report to describe resolution of OROS-MPH-induced hair loss after dose escalation. © 2017 Japan Pediatric Society.

  16. HRR Profiling on Integrated Radar-Communication Systems Using OFDM-PCSF Signals

    Directory of Open Access Journals (Sweden)

    Xuanxuan Tian

    2017-01-01

    Full Text Available In order to improve both the transmission data rate and the range resolution simultaneously in integrated radar-communication (RadCom systems, orthogonal frequency-division multiplexing with phase-coded and stepped-frequency (OFDM-PCSF waveform is proposed. A corresponding high resolution range (HRR profile generation method is also presented. We first perform OFDM-PCSF waveform design by combining the intrapulse phase coding with the interpulse stepped-frequency modulation. We then give the ambiguity function (AF based on the presented waveforms. Then, the synthetic range profile (SRP processing to achieve HRR performance is analyzed. Theoretical analysis and simulation results show that the proposed methods can achieve HRR profiles of the targets and high data rate transmissions, while a relative low computational complexity can be achieved.

  17. Measurement system of bubbly flow using ultrasonic velocity profile monitor and video data processing unit

    International Nuclear Information System (INIS)

    Aritomi, Masanori; Zhou, Shirong; Nakajima, Makoto; Takeda, Yasushi; Mori, Michitsugu; Yoshioka, Yuzuru.

    1996-01-01

    The authors have been developing a measurement system for bubbly flow in order to clarify its multi-dimensional flow characteristics and to offer a data base to validate numerical codes for multi-dimensional two-phase flow. In this paper, the measurement system combining an ultrasonic velocity profile monitor with a video data processing unit is proposed, which can measure simultaneously velocity profiles in both gas and liquid phases, a void fraction profile for bubbly flow in a channel, and an average bubble diameter and void fraction. Furthermore, the proposed measurement system is applied to measure flow characteristics of a bubbly countercurrent flow in a vertical rectangular channel to verify its capability. (author)

  18. Initial development of an automated task analysis profiling system

    International Nuclear Information System (INIS)

    Jorgensen, C.C.

    1984-01-01

    A program for automated task analysis is described. Called TAPS (task analysis profiling system), the program accepts normal English prose and outputs skills, knowledges, attitudes, and abilities (SKAAs) along with specific guidance and recommended ability measurement tests for nuclear power plant operators. A new method for defining SKAAs is presented along with a sample program output

  19. Input-profile-based software failure probability quantification for safety signal generation systems

    International Nuclear Information System (INIS)

    Kang, Hyun Gook; Lim, Ho Gon; Lee, Ho Jung; Kim, Man Cheol; Jang, Seung Cheol

    2009-01-01

    The approaches for software failure probability estimation are mainly based on the results of testing. Test cases represent the inputs, which are encountered in an actual use. The test inputs for the safety-critical application such as a reactor protection system (RPS) of a nuclear power plant are the inputs which cause the activation of protective action such as a reactor trip. A digital system treats inputs from instrumentation sensors as discrete digital values by using an analog-to-digital converter. Input profile must be determined in consideration of these characteristics for effective software failure probability quantification. Another important characteristic of software testing is that we do not have to repeat the test for the same input value since the software response is deterministic for each specific digital input. With these considerations, we propose an effective software testing method for quantifying the failure probability. As an example application, the input profile of the digital RPS is developed based on the typical plant data. The proposed method in this study is expected to provide a simple but realistic mean to quantify the software failure probability based on input profile and system dynamics.

  20. The impact of microgeometry pistons with a stepped bearing surface for the friction loss of the internal combustion engine

    Directory of Open Access Journals (Sweden)

    Wroblewski Emil

    2017-01-01

    Full Text Available This paper present the results of experimental piston friction losses on stepped bearing surface microgeometry obtained on the test rig. This test rig is equipped with special temperature control system, which provides better stability to temperature than in standard systems. The results of station tests was discussed. Tests was analyzed depending the moment caused by the friction on the oil temperature in the oil sump. Specified conclusions allow to assess the impact of the stepped profile of the pistons bearing surface microgeometry for different values of engine speed and the oil temperature at the friction losses in the main kinematic engine node which is piston-cylinder.

  1. Anomalous waves propagating at very high frequency in the atmosphere and their disturbances due to changes in refractivity profiles

    Directory of Open Access Journals (Sweden)

    Imtiaz Alam

    2018-03-01

    Full Text Available Anomalous waves propagation is severely affected due to almost always present variations in refractivity under various environmental conditions at different time, location and frequency. These conditions, representing different state of the atmosphere including e.g. foggy, rainy and cloudy etc., not only degrade the quality of the signal but sometimes completely eradicate the communication link. Such severe impact on propagation cannot be ignored by the designers of communication systems. The aim of this research is to present correlation between experimental and modelled link losses for variations in refractivity values recommended by International Telecommunication Union-Recommendations (ITU-R as well as that of standard profiles. To do so, a communication setup of 50 km over the Sea operating experimentally over a period of a year at 240 MHz is analyzed for different refractivity profiles and their impact on propagation. A median value is taken for every set of 6000 values taken from the recorded data set of more than 48 million experimental link losses. This reduces the huge data set of the experimental link losses to 8000 values only. This reduced data set of experimental and modelled link losses were correlated and investigated for different evaporation duct heights throughout the year. For the considered link, the ITU-R refractivity profile was found to perform better than the standard refractivity profile. However, the new findings as observed in this research, which may be helpful for the recommendations authorities, is the existing of evaporation duct up to 10 m height. Keywords: Parabolic equation, Link loss, Refractivity, Propagation, Troposphere, Very high frequency

  2. Power profiling of Cholesky and QR factorizations on distributed memory systems

    KAUST Repository

    Bosilca, George

    2012-08-30

    This paper presents the power profile of two high performance dense linear algebra libraries on distributed memory systems, ScaLAPACK and DPLASMA. From the algorithmic perspective, their methodologies are opposite. The former is based on block algorithms and relies on multithreaded BLAS and a two-dimensional block cyclic data distribution to achieve high parallel performance. The latter is based on tile algorithms running on top of a tile data layout and uses fine-grained task parallelism combined with a dynamic distributed scheduler (DAGuE) to leverage distributed memory systems. We present performance results (Gflop/s) as well as the power profile (Watts) of two common dense factorizations needed to solve linear systems of equations, namely Cholesky and QR. The reported numbers show that DPLASMA surpasses ScaLAPACK not only in terms of performance (up to 2X speedup) but also in terms of energy efficiency (up to 62 %). © 2012 Springer-Verlag (outside the USA).

  3. Dew-point hygrometry system for measurement of evaporative water loss in infants.

    Science.gov (United States)

    Ariagno, R L; Glotzbach, S F; Baldwin, R B; Rector, D M; Bowley, S M; Moffat, R J

    1997-03-01

    Evaporation of water from the skin is an important mechanism in thermal homeostasis. Resistance hygrometry, in which the water vapor pressure gradient above the skin surface is calculated, has been the measurement method of choice in the majority of pediatric investigations. However, resistance hygrometry is influenced by changes in ambient conditions such as relative humidity, surface temperature, and convection currents. We have developed a ventilated capsule method that minimized these potential sources of measurement error and that allowed second-by-second, long-term, continuous measurements of evaporative water loss in sleeping infants. Air with a controlled reference humidity (dew-point temperature = 0 degree C) is delivered to a small, lightweight skin capsule and mixed with the vapor on the surface of the skin. The dew point of the resulting mixture is measured by using a chilled mirror dew-point hygrometer. The system indicates leaks, is mobile, and is accurate within 2%, as determined by gravimetric calibration. Examples from a recording of a 13-wk-old full-term infant obtained by using the system give evaporative water loss rates of approximately 0.02 mgH2O.cm-2.min-1 for normothermic baseline conditions and values up to 0.4 mgH2O.cm-2. min-1 when the subject was being warmed. The system is effective for clinical investigations that require dynamic measurements of water loss.

  4. Molecular depth profiling of multi-layer systems with cluster ion sources

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Juan [Department of Chemistry, Penn State University, University Park, PA 16802 (United States); Winograd, Nicholas [Department of Chemistry, Penn State University, University Park, PA 16802 (United States)]. E-mail: nxw@psu.edu

    2006-07-30

    Cluster bombardment of molecular films has created new opportunities for SIMS research. To more quantitatively examine the interaction of cluster beams with organic materials, we have developed a reproducible platform consisting of a well-defined sugar film (trehalose) doped with peptides. Molecular depth profiles have been acquired with these systems using C{sub 60} {sup +} bombardment. In this study, we utilize this platform to determine the feasibility of examining buried interfaces for multi-layer systems. Using C{sub 60} {sup +} at 20 keV, several systems have been tested including Al/trehalose/Si, Al/trehalose/Al/Si, Ag/trehalose/Si and ice/trehalose/Si. The results show that there can be interactions between the layers during the bombardment process that prevent a simple interpretation of the depth profile. We find so far that the best results are obtained when the mass of the overlayer atoms is less than or nearly equal to the mass of the atoms in buried molecules. In general, these observations suggest that C{sub 60} {sup +} bombardment can be successfully applied to interface characterization of multi-layer systems if the systems are carefully chosen.

  5. Evaluation to Mitigate Secondary System Peak Pressure for Loss of Condenser Vacuum Event

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Bong Oh; Park, Jong Cheol; Park, Min Soo; Lee, Gyu Cheon; Kim, Shin Whan [KEPCO E and C, Inc., Daejeon (Korea, Republic of)

    2015-10-15

    In this paper, countermeasures to compensate the increased secondary pressure are introduced and evaluated. From the standpoint of the secondary system pressurization, consideration of the PPCS may result in a conservative secondary system peak pressure. The control systems are generally credited for the safety analysis if the analysis produces conservative results. However, in most of all non-loss of coolant accident (non-LOCA) events, the control system helps to mitigate a transient state. Accordingly, the safety analysis of non-LOCA assumes the control systems are in the manual mode of operation. The loss of condenser vacuum event (LOCV) is a typical anticipated operational occurrence (AOO) which results in an increase in primary and secondary system pressure. The pressurizer (PZR) pressure control system (PPCS) will function to reduce the primary system pressure increase during the transient. Therefore, it is assumed to be in manual mode and credit is not taken for its functioning. However, crediting the function of PPCS has been found to be more conservative with regard to the secondary system pressure. This is due to the delay of the reactor trip on high pressurizer pressure (HPP) and results in an increase in secondary pressure.

  6. Technology Roadmap. Energy Loss Reduction and Recovery in Industrial Energy Systems

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2004-11-01

    To help guide R&D decision-making and gain industry insights on the top opportunities for improved energy systems, ITP sponsored the Energy Loss Reduction and Recoveryin Energy Systems Roadmapping Workshopin April 2004 in Baltimore, Maryland. This Technology Roadmapis based largely on the results of the workshop and additional industrial energy studies supported by ITP and EERE. It summarizes industry feedback on the top opportunities for R&D investments in energy systems, and the potential for national impacts on energy use and the environment.

  7. A measurement system for vertical seawater profiles close to the air–sea interface

    Directory of Open Access Journals (Sweden)

    R. P. Sims

    2017-09-01

    Full Text Available This paper describes a near-surface ocean profiler, which has been designed to precisely measure vertical gradients in the top 10 m of the ocean. Variations in the depth of seawater collection are minimized when using the profiler compared to conventional CTD/rosette deployments. The profiler consists of a remotely operated winch mounted on a tethered yet free-floating buoy, which is used to raise and lower a small frame housing sensors and inlet tubing. Seawater at the inlet depth is pumped back to the ship for analysis. The profiler can be used to make continuous vertical profiles or to target a series of discrete depths. The profiler has been successfully deployed during wind speeds up to 10 m s−1 and significant wave heights up to 2 m. We demonstrate the potential of the profiler by presenting measured vertical profiles of the trace gases carbon dioxide and dimethylsulfide. Trace gas measurements use an efficient microporous membrane equilibrator to minimize the system response time. The example profiles show vertical gradients in the upper 5 m for temperature, carbon dioxide and dimethylsulfide of 0.15 °C, 4 µatm and 0.4 nM respectively.

  8. Computational Approach to Profit Optimization of a Loss-Queueing System

    Directory of Open Access Journals (Sweden)

    Dinesh Kumar Yadav

    2010-01-01

    Full Text Available Objective of the paper is to deal with the profit optimization of a loss queueing system with the finite capacity. Here, we define and compute total expected cost (TEC, total expected revenue (TER and consequently we compute the total optimal profit (TOP of the system. In order to compute the total optimal profit of the system, a computing algorithm has been developed and a fast converging N-R method has been employed which requires least computing time and lesser memory space as compared to other methods. Sensitivity analysis and its observations based on graphics have added a significant value to this model.

  9. Emergency core cooling system sump chemical effects on strainer head loss

    International Nuclear Information System (INIS)

    Edwards, M.K.; Qiu, L.; Guzonas, D.A.

    2010-01-01

    Chemical precipitates formed in the recovery water following a Loss of Coolant Accident (LOCA) have the potential to increase head loss across the Emergency Core Cooling System (ECCS) strainer, and could lead to cavitation of the ECCS pumps, pump failure and loss of core cooling. AECL, as a strainer vendor and research organization, has been involved in the investigation of chemical effects on head loss for its CANDU® and Pressurized Water Reactor (PWR) customers. The chemical constituents of the recovery sump water depend on the combination of chemistry control additives and the corrosion and dissolution products from metals, concrete, and insulation materials. Some of these dissolution and corrosion products (e.g., aluminum and calcium) may form significant quantities of precipitates. The presence of chemistry control additives such as sodium hydroxide, trisodium phosphate and boric acid can significantly influence the precipitates formed. While a number of compounds may be shown to be thermodynamically possible under the conditions assumed for precipitation, kinetic factors play a large role in the morphology of precipitates. Precipitation is also influenced by insulation debris, which can trap precipitates and act as nucleation sites for heterogeneous precipitation. This paper outlines the AECL approach to resolving the issue of chemical effects on ECCS strainer head loss, which included modeling, bench top testing and reduced-scale testing; the latter conducted using a temperature-controlled variable-flow closed-loop test rig that included an AECL Finned Strainer® test section equipped with a differential pressure transmitter. Models of corrosion product release and the effects of precipitates on head loss will also be presented. Finally, this paper discusses the precipitates found in test debris beds and presents a possible method for chemical effects head loss modeling. (author)

  10. Based on the rainfall system platform raindrops research and analysis of pressure loss

    Science.gov (United States)

    Cao, Gang; Sun, Jian

    2018-01-01

    With the rapid development of China’s military career, land, sea and air force all services and equipment of modern equipment need to be in the rain test, and verify its might suffer during transportation, storage or use a different environment temperature lower water or use underwater, the water is derived from the heavy rain, the wind and rain, sprinkler system, splash water, water wheel, a violent shock waves or use underwater, etcTest the product performance and quality, under the condition of rainfall system platform in the process of development, how to control the raindrops pressure loss becomes the key to whether the system can simulate the real rainfall [1], this paper is according to the rainfall intensity, nozzle flow resistance, meet water flow of rain pressure loss calculation and analysis, and system arrangement of the optimal solution of rainfall is obtained [2].

  11. A mathematical technique for hybrid power system design with energy loss considerations

    International Nuclear Information System (INIS)

    Lee, Jui-Yuan; Chen, Cheng-Liang; Chen, Hui-Chu

    2014-01-01

    Highlights: • A superstructure-based model is developed for hybrid power system design. • The model considers various power losses occurring in hybrid power systems. • The model locates rigorous outsourced electricity targets. • The model determines the minimum electricity storage capacity required. • Three literature case studies are solved to demonstrate the use of the model. - Abstract: This paper presents a generic mathematical optimisation model for the design of hybrid power systems (HPSs). The model takes into account power losses during the allocation of power generated from renewables to appliance loads, and is formulated as a linear programme (LP) based on a superstructure including all possible power allocation options in a typical HPS. With given power source and demand data for an HPS, the minimum outsourced electricity supply and the minimum electricity storage capacity required can be determined through a two-step optimisation. Three literature case studies are solved to illustrate the proposed approach

  12. NPP Krsko analysis of the loss of the RHR system during mid-loop operation

    International Nuclear Information System (INIS)

    Bencik, V.; Feretic, D.; Debrecin, N.

    2002-01-01

    In the paper the results of the NPP Krsko analysis of the loss of the Residual Heat Removal (RHR) system at mid-loop conditions using RELAP5/MOD 3.2.2 Gamma and RELAP5/MOD 3.3 Beta code are presented. Both pressurizer and Steam Generator (SG) 1 manway were open. The facility was open to the containment atmosphere and filled with air above liquid level. Loss of the RHR system when Reactor Coolant System (RCS) is open causes quick boiling in the core and loss of the inventory available for the cooling of the core through the openings. Aims of the analysis were threefold. First, the consequences of the transient for NPP Krsko, i.e., the time to core uncovery was determined. Secondly, the influence of the applied RELAP5 code version (MOD 3.2.2 Gamma and MOD 3.3 Beta) in the analysis of that particular transient with noncondensable gases was assessed. Third, the analysis with SG secondary sides under wet lay-up conditions was performed in order to assess the influence of condensation in the SG U tubes on liquid inventory in the system and core cooling capability.(author)

  13. HURRICANE AND SEVERE STORM SENTINEL (HS3) GLOBAL HAWK ADVANCED VERTICAL ATMOSPHERIC PROFILING SYSTEM (AVAPS) DROPSONDE SYSTEM V2

    Data.gov (United States)

    National Aeronautics and Space Administration — The Hurricane and Severe Storm Sentinel (HS3) Global Hawk Advanced Vertical Atmospheric Profiling System (AVAPS) Dropsonde System dataset was collected by the...

  14. Effect of sugarcane cropping systems on herbicide losses in surface runoff.

    Science.gov (United States)

    Nachimuthu, Gunasekhar; Halpin, Neil V; Bell, Michael J

    2016-07-01

    Herbicide runoff from cropping fields has been identified as a threat to the Great Barrier Reef ecosystem. A field investigation was carried out to monitor the changes in runoff water quality resulting from four different sugarcane cropping systems that included different herbicides and contrasting tillage and trash management practices. These include (i) Conventional - Tillage (beds and inter-rows) with residual herbicides used; (ii) Improved - only the beds were tilled (zonal) with reduced residual herbicides used; (iii) Aspirational - minimum tillage (one pass of a single tine ripper before planting) with trash mulch, no residual herbicides and a legume intercrop after cane establishment; and (iv) New Farming System (NFS) - minimum tillage as in Aspirational practice with a grain legume rotation and a combination of residual and knockdown herbicides. Results suggest soil and trash management had a larger effect on the herbicide losses in runoff than the physico-chemical properties of herbicides. Improved practices with 30% lower atrazine application rates than used in conventional systems produced reduced runoff volumes by 40% and atrazine loss by 62%. There were a 2-fold variation in atrazine and >10-fold variation in metribuzin loads in runoff water between reduced tillage systems differing in soil disturbance and surface residue cover from the previous rotation crops, despite the same herbicide application rates. The elevated risk of offsite losses from herbicides was illustrated by the high concentrations of diuron (14μgL(-1)) recorded in runoff that occurred >2.5months after herbicide application in a 1(st) ratoon crop. A cropping system employing less persistent non-selective herbicides and an inter-row soybean mulch resulted in no residual herbicide contamination in runoff water, but recorded 12.3% lower yield compared to Conventional practice. These findings reveal a trade-off between achieving good water quality with minimal herbicide contamination and

  15. CLIQ – Coupling-Loss Induced Quench System for Protecting Superconducting Magnets

    CERN Multimedia

    Ravaioli, E; Kirby, G; ten Kate, H H J; Verweij, A P

    2014-01-01

    The recently developed Coupling-Loss-Induced Quench (CLIQ) protection system is a new method for initiating a fast and voluminous transition to the normal state for protecting high energy density superconducting magnets. Upon quench detection, CLIQ is triggered to generate an oscillating current in the magnet coil by means of a capacitive discharge. This in turn introduces a high coupling loss in the superconductor which provokes a quick transition to the normal state of the coil windings. The system is now implemented for the protection of a two meter long superconducting quadrupole magnet and characterized in the CERN magnet test facility. Various CLIQ configurations with different current injection points are tested and the results compared to similar transients lately measured with a not optimized configuration. Test results convincingly show that the newly tested design allows for a more global quench initiation and thus a faster discharge of the magnet energy. Moreover, the performance of CLIQ for reduc...

  16. Epidemiological profile of reproductive loss in dairy cattle

    Directory of Open Access Journals (Sweden)

    Raul Costa Mascarenhas Santana

    2012-12-01

    Full Text Available Several agents can be present in dairy cattle with a history of abortion as Neospora caninum, Leptospira spp, Bovine Herpesvirus Type 1 (BHV-1 and Brucella abortus. Some of these are considered transmitters cosmopolitan zoonosis of great economic impact and risk to human and animal health. The aim of this work was draw an epidemiological profile of reproductive losses and to determine the prevalence of antibodies against the main agents of reproductive diseases in dairy cattle. The study was conducted on a property in São Carlos city. For determination of reproductive failure, pre-existing data of abortion and stillbirths were analyzed from January 2006 to December 2011 on an average of 274 dairy cows of Holstein and crossbred Holstein-Jersey. On March 1, 2012 blood serum samples were collected of 142 breeding animals of ages above two years, in which 21.1% showed cases of abortions or stillbirths of at least one pregnancy. We used serologic tests of microscopic agglutination test, immunofluorescent antibody technique, serum neutralization technique, tamponated acidified antigen test for detection of anti-Leptospira spp and anti-Neospora caninum, anti-Bovine Herpesvirus Type-1 (BHV-1 and anti- Brucella abortus, respectively. The tests were performed at Universidade Estadual Paulista, Botucatu and Jaboticabal campi and EMBRAPA Southeast Livestock. During the study period, it was observed an average monthly rate of 1.7 abortions and 0.7 stillbirths, with an incidence of 63.6% and 58.0% of the cases observed, respectively, between November and April, period of higher pluviometric precipitation in the region. Among the cases of abortions observed, 76.2% happened between the fourth and sixth month of pregnancy. The serological tests carried out showed that 15.5% of the animals had titers greater than or equal to 1:200 of anti-Neospora caninum. Among the animals with a history of abortions or stillbirths, 28.58% and 11.22%, respectively, were serum

  17. A robust fibre laser system for electro-optic electron bunch profile measurements at FLASH

    Energy Technology Data Exchange (ETDEWEB)

    Wissmann, Laurens-Georg

    2012-08-15

    For the electro-optic measurement of electron bunch profiles at FLASH a robust ytterbium doped fibre laser (YDFL) system has been developed consisting of a laser oscillator and a two-staged amplifier. The oscillator is designed to meet the specifications of high reliability and low noise operation. The amplifier makes use of tailored nonlinearity to enhance the spectral bandwidth of the output laser pulses. Active repetition rate control enables sub-picosecond synchronisation of the laser to the accelerator reference RF. Using a two-stage gating scheme the output pulse train repetition rate is adopted to the accelerator repetition rate. An experimental site used for electro-optic electron bunch diagnostics has been redesigned to support single-shot bunch profile measurements based on spectral decoding. An existing bunch profile monitor with a similar laser system was upgraded and electro-optic bunch profile measurements were conducted, allowing for a comparison with measurements done with other longitudinal electron bunch diagnostics and with former measurements.

  18. A robust fibre laser system for electro-optic electron bunch profile measurements at FLASH

    International Nuclear Information System (INIS)

    Wissmann, Laurens-Georg

    2012-08-01

    For the electro-optic measurement of electron bunch profiles at FLASH a robust ytterbium doped fibre laser (YDFL) system has been developed consisting of a laser oscillator and a two-staged amplifier. The oscillator is designed to meet the specifications of high reliability and low noise operation. The amplifier makes use of tailored nonlinearity to enhance the spectral bandwidth of the output laser pulses. Active repetition rate control enables sub-picosecond synchronisation of the laser to the accelerator reference RF. Using a two-stage gating scheme the output pulse train repetition rate is adopted to the accelerator repetition rate. An experimental site used for electro-optic electron bunch diagnostics has been redesigned to support single-shot bunch profile measurements based on spectral decoding. An existing bunch profile monitor with a similar laser system was upgraded and electro-optic bunch profile measurements were conducted, allowing for a comparison with measurements done with other longitudinal electron bunch diagnostics and with former measurements.

  19. The Impact of Connecting Distributed Generation to the Distribution System

    Directory of Open Access Journals (Sweden)

    E. V. Mgaya

    2007-01-01

    Full Text Available This paper deals with the general problem of utilizing of renewable energy sources to generate electric energy. Recent advances in renewable energy power generation technologies, e.g., wind and photovoltaic (PV technologies, have led to increased interest in the application of these generation devices as distributed generation (DG units. This paper presents the results of an investigation into possible improvements in the system voltage profile and reduction of system losses when adding wind power DG (wind-DG to a distribution system. Simulation results are given for a case study, and these show that properly sized wind DGs, placed at carefully selected sites near key distribution substations, could be very effective in improving the distribution system voltage profile and reducing power losses, and hence could  improve the effective capacity of the system

  20. Building America Top Innovations 2013 Profile – Quality Management System Guidelines

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2013-09-01

    This Top Innovation profile describes quality management system tools that were customized for residential construction by BSC, IBACOS, and PHI, for use by builders, trades, and designers to help eliminate mistakes that would require high-cost rework.

  1. Improving electronic customers' profile in recommender systems using data mining techniques

    Directory of Open Access Journals (Sweden)

    Mohammad Julashokri

    2011-10-01

    Full Text Available Recommender systems are tools for realization one to one marketing. Recommender systems are systems, which attract, retain, and develop customers. Recommender systems use several ways to make recommendations. Two ways are using more than the others: collaborative filtering and content-based filtering. In this study, a recommender system model based on collaborative filtering has proposed. Proposed model was endeavored to improve the customer profile in collaborative systems to enhance the recommender system efficiency. This improvement was done using time context and group preferences. Experimental results show that the proposed model has a better recommendation performance than existing models.

  2. The Effect of Electric Load Profiles on the Performance of Off-Grid Residential Hybrid Renewable Energy Systems

    Directory of Open Access Journals (Sweden)

    Stephen Treado

    2015-10-01

    Full Text Available This paper investigates the energy performance of off-grid residential hybrid renewable electric power systems, particularly the effect of electric load profiles on the ability to harvest available solar energy and avoid the consumption of auxiliary energy in the form of propane. The concepts are illustrated by an analysis of the energy performance of electric and propane-fired refrigerators. Off-grid electric power systems frequently incorporate a renewable source, such as wind or solar photovoltaic (PV, with a back-up power provided by a propane fueled motor/generator. Among other design decisions, residential consumers face the choice of employing an electric refrigerator with a conventional vapor compression refrigeration system, or a fuel-fired refrigerator operating as an absorption refrigeration system. One interesting question is whether it is more advantageous from an energy perspective to use electricity to run the refrigerator, which might be provided by some combination of the PV and propane motor/generator, thereby taking advantage of the relatively higher electric refrigerator Coefficient of Performance (COP and free solar energy but having to accept a low electrical conversion efficiency of the motor/generator, or use thermal energy from the combustion of propane to produce the refrigeration effect via an absorption system, albeit with a much lower COP. The analysis is complicated by the fact that most off-grid renewable electrical power systems utilize a battery bank to provide electrical power when it is not available from the wind turbine or PV system, so the state of charge of the battery bank will have a noticeable impact on what energy source is available at any moment in time. Daily electric load profiles combined with variable solar energy input determine the state of charge of the battery bank, with the degree of synchronization between the two being a critical factor in determining performance. The annual energy usage

  3. Model for Calculating Electrolytic Shunt Path Losses in Large Electrochemical Energy Conversion Systems

    Science.gov (United States)

    Prokopius, P. R.

    1976-01-01

    Generalized analysis and solution techniques were developed to evaluate the shunt power losses in electrochemical systems designed with a common or circulating electrolyte supply. Sample data are presented for a hypothetical bulk energy storage redox system, and the general applicability of the analysis technique is discussed.

  4. Radial diffusion in the Uranian radiatian belts - Inferences from satellite absorption loss models

    Science.gov (United States)

    Hood, L. L.

    1989-01-01

    Low-energy charged particle (LECP) phase space density profiles available from the Voyager/1986 Uranus encounter are analyzed, using solutions of the time-averaged radial diffusion equation for charged particle transport in a dipolar planetary magnetic field. Profiles for lower-energy protons and electrons are first analyzed to infer radial diffusion rate as a function of L, assuming that satellite absorption is the dominant loss process and local sources for these particles are negligible. Satellite macrosignatures present in the experimentally derived profiles are approximately reproduced in several cases, lending credence to the loss model and indicating that magnetospheric distributed losses are not as rapid as satellite absorption near the minimum satellite L shells for the particles. Diffusion rates and L dependences are found to be similar to those previously inferred in the inner Jovian magnetosphere (Thomsen et al., 1977) and for the inner Saturnian magnetosphere (Hood, 1985). Profiles for higher energy electrons and protons are also analyzed using solutions that allow for the existence of significant particle sources as well as sinks. Possible implications for radial diffusion mechanisms in the Uranian radiation belts are discussed.

  5. Behaviour of direct and delayed fast ion losses during NBI on TJ-II

    International Nuclear Information System (INIS)

    Guasp, J.; Liniers; M.

    1995-09-01

    The dependence with density and beam energy of the different kind of fast ion losses, direct and delayed, during tangential balanced NBI injection in TJ-II helical axis stellerator has been analysed. Direct losses increase with energy and a strong difference between the two injection directions appears, are produced by passing particles that loss confinement in a dew mu,sec and the influence of birth profiles produces an increase with density. Delayed losses are very well separated in time from direct ones, are produced by particles experimenting pitch angle scattering an,d, most o them, correspond to trapped particles. Are much less important than the direct ones (about 1/3), decrease slowly with energy and, with CX, increase with density (an effect of initial profile). The absorption is rather independent of energy with low values at low density in reason of high shine trough and CX losses, but reovers quickly with the density increase

  6. Behaviour of direct and delayed fast ion losses during NBI on TJ-II

    International Nuclear Information System (INIS)

    Guasp, J.; Liniers, M.

    1995-01-01

    The dependence with density and beam energy of the different kind of fast ion losses, direct and delayed, during tangential balanced NBI injection in TJ-II helical axis stellarator has been analysed. Direct losses increase with energy and a strong difference between the two injection directions appears, are produced by passing particles that loss confinement in a few μsec and the influence of birth profiles produces an increase with density. Delayed losses are very well separated in time from direct ones, are produced by particles experimenting pitch angle scattering and, most o them, correspond to trapped particles. Are much less important than the direct ones (about 1/3), decrease slowly with energy and, with C X, increase with density (an effect of initial profile). The absorption is rather independent of energy with low values at low density in reason of high shine through and C X losses, but recovers quickly with the density increase. (Author) 4 refs

  7. Assessing temporal couplings in social-ecological island systems: historical deforestation and soil loss on Mauritius (Indian Ocean

    Directory of Open Access Journals (Sweden)

    S.J. Norder

    2017-03-01

    Full Text Available Temporal couplings, such as historical interactions between deforestation and soil loss, are responsible for the current state of a wide range of ecosystem services of the social-ecological system on Mauritius. Islands are suitable study sites for understanding temporal couplings and telecouplings because of their: (1 clearly defined physical boundaries, (2 finite local resources, and (3 relatively short human history. Six well-documented historical deforestation maps, starting from the first colonization of Mauritius in 1638, were used as input parameters to model two scenarios of cumulative soil loss, with and without deforestation, using the revised universal soil loss equation in a geographic information system. The scenarios show that historical deforestation since 1638 has resulted in a cumulative soil loss that drastically exceeds soil loss under a natural baseline scenario without deforestation. The adopted method illustrates to what extent the current state of the soil of a social-ecological system is negatively affected by past human-environment interactions. We suggest that potential negative impacts on insular societies are mitigated by telecouplings such as food, fuel, and fertilizer imports.

  8. A Profile-Based Identification of Standby and Useless Electricity Consumption in Buildings

    OpenAIRE

    De Koster, Rien; Van Roy, Juan; Driesen, Johan

    2013-01-01

    Useless electricity consumption is the electricity consumption of an electric appliance or system that is not performing its primary function or that is performing its primary function without being useful. So, useless electricity consumption does not only consist of standby losses. To identify the useless electricity consumption in a building, a profile-based approach is developed. This approach is used to investigate the useless electricity consumption in five buildings of the University of...

  9. Thermal energy storage and losses in a room-Trombe wall system located in Mexico

    International Nuclear Information System (INIS)

    Hernández-López, I.; Xamán, J.; Chávez, Y.; Hernández-Pérez, I.; Alvarado-Juárez, R.

    2016-01-01

    A thermal evaluation of a R-TW system (room with a Trombe wall) is presented. Hourly climatic data of the coldest and the warmest days of 2014 was used to assess the behavior of the R-TW in two cities of Mexico with cold climate (Huitzilac and Toluca). The simulations were done with an in-house code based on the Finite Volume Method. It was found that thermal energy losses through the semitransparent wall are about 60% of the solar radiation incident on the system (G_s_o_l). Despite of the thermal losses, the system gets enough energy to keep the air inside the room with a temperature above 35 °C. For both cities during the coldest day, the maximum energy stored is about 109 MJ and during the warmest day is about 70 MJ. This energy is supplied from the storage wall to the air inside the room during periods without insolation. - Highlights: • Thermal performance of a Room-Trombe Wall system was evaluated under two cold cities. • Thermal energy losses through the semitransparent wall were about 60% of the solar radiation incident of the system. • The maximum energy stored by the Trombe Wall was 109 MJ during the coldest day. • The maximum energy stored by the Trombe Wall was 70 MJ during the warmest day.

  10. Economic-based design of engineering systems with degrading components using probabilistic loss of quality

    International Nuclear Information System (INIS)

    Son, Young Kap; Savage, Gordon J.; Chang, Seog Weon

    2007-01-01

    The allocation of means and tolerances to provide quality, functional reliability and performance reliability in engineering systems is a challenging problem. Traditional measures to help select the best means and tolerances include mean time to failure and its variance: however, they have some shortcomings. In this paper, a monetary measure based on present worth is invoked as a more inclusive metric. We consider the sum of the production cost and the expected loss of quality cost over a planned horizon at the customer's discount rates. Key to the approach is a probabilistic loss of quality cost that incorporates the cumulative distribution function that arises from time-variant distributions of system performance measures due to degrading components. The proposed design approach investigates both degradation and uncertainty in component. Moreover, it tries to obviate problems of current Taguchi's loss function-based design approaches. Case studies show the practicality and promise of the approach

  11. Energy demand and thermal comfort of HVAC systems with thermally activated building systems as a function of user profile

    Science.gov (United States)

    Pałaszyńska, Katarzyna; Bandurski, Karol; Porowski, Mieczysław

    2017-11-01

    Thermally Activated Building Systems (TABS) are a way to use building structure as a thermal energy storage. As a result, renewable energy sources may be used more efficiently. The paper presents numerical analysis of a HVAC system with TABS energy demand and indoor thermal comfort of a representative room in a non-residential building (governmental, commercial, educational). The purpose of analysis is to investigate the influence of a user profile on system performance. The time span of the analysis is one year - a typical meteorological year. The model was prepared using a generally accepted simulation tool - TRNSYS 17. The results help to better understand the interaction of a user profile with TABS. Therefore they are important for the development of optimal control algorithms for energy efficient buildings equipped with such systems.

  12. Look-ahead policies for admission to a single server loss system

    NARCIS (Netherlands)

    Nawijn, W.M.

    1990-01-01

    Consider a single server loss system in which the server, being idle, may reject or accept an arriving customer for service depending on the state at the arrival epoch. It is assumed that at every arrival epoch the server knows the service time of the arriving customer, the arrival time of the next

  13. Prolonged grief and depression after unnatural loss : Latent class analyses and cognitive correlates

    NARCIS (Netherlands)

    Boelen, Paul A; Reijntjes, Albert; J Djelantik, A A A Manik; Smid, Geert E

    2016-01-01

    This study sought to identify (a) subgroups among people confronted with unnatural/violent loss characterized by different symptoms profiles of prolonged grief disorder (PGD) and depression, and (b) socio-demographic, loss-related, and cognitive variables associated with subgroup membership. We used

  14. Effects of wireless packet loss in industrial process control systems.

    Science.gov (United States)

    Liu, Yongkang; Candell, Richard; Moayeri, Nader

    2017-05-01

    Timely and reliable sensing and actuation control are essential in networked control. This depends on not only the precision/quality of the sensors and actuators used but also on how well the communications links between the field instruments and the controller have been designed. Wireless networking offers simple deployment, reconfigurability, scalability, and reduced operational expenditure, and is easier to upgrade than wired solutions. However, the adoption of wireless networking has been slow in industrial process control due to the stochastic and less than 100% reliable nature of wireless communications and lack of a model to evaluate the effects of such communications imperfections on the overall control performance. In this paper, we study how control performance is affected by wireless link quality, which in turn is adversely affected by severe propagation loss in harsh industrial environments, co-channel interference, and unintended interference from other devices. We select the Tennessee Eastman Challenge Model (TE) for our study. A decentralized process control system, first proposed by N. Ricker, is adopted that employs 41 sensors and 12 actuators to manage the production process in the TE plant. We consider the scenario where wireless links are used to periodically transmit essential sensor measurement data, such as pressure, temperature and chemical composition to the controller as well as control commands to manipulate the actuators according to predetermined setpoints. We consider two models for packet loss in the wireless links, namely, an independent and identically distributed (IID) packet loss model and the two-state Gilbert-Elliot (GE) channel model. While the former is a random loss model, the latter can model bursty losses. With each channel model, the performance of the simulated decentralized controller using wireless links is compared with the one using wired links providing instant and 100% reliable communications. The sensitivity of the

  15. Thermal analysis of CANDU6 moderator system for loss of cooling

    International Nuclear Information System (INIS)

    Xu Zhen

    2012-01-01

    The coolant system and moderator system of CANDU6 are independent. The prompt neutrons are moderated as thermal neutrons by the moderator and the continuous nuclear fission in the reactor is maintained. At the same time the moderator system supplies the heat sink for the heat produced by the neutrons moderation. During the in-service maintenance of plant, the standby RCW which will only cool down reactor coolant system operates instead of RCW and can not supply heat sink for moderator system heat exchanger. As the result, the moderator system will lose heat sink during the operation of standby RCW. To estimate the moderator temperature, the thermal analysis of moderator system for loss of cooling was compared with the experiment data and the system failure caused by the temperature raising was evaluated in this paper. (author)

  16. Policy outcomes of applying different nutrient profiling systems in recreational sports settings: the case for national harmonization in Canada.

    Science.gov (United States)

    Olstad, Dana Lee; Poirier, Kelly; Naylor, Patti-Jean; Shearer, Cindy; Kirk, Sara F L

    2015-08-01

    To assess agreement among three nutrient profiling systems used to evaluate the healthfulness of vending machine products in recreation and sport settings in three Canadian provinces. We also assessed whether the nutritional profile of vending machine items in recreation and sport facilities that were adhering to nutrition guidelines (implementers) was superior to that of facilities that were not (non-implementers). Trained research assistants audited the contents of vending machines. Three provincial nutrient profiling systems were used to classify items into each province's most, moderately and least healthy categories. Agreement among systems was assessed using weighted κ statistics. ANOVA assessed whether the average nutritional profile of vending machine items differed according to province and guideline implementation status. Eighteen recreation and sport facilities in three Canadian provinces. One-half of facilities were implementing nutrition guidelines. Snacks (n 531) and beverages (n 618) within thirty-six vending machines were audited. Overall, the systems agreed that the majority of items belonged within their respective least healthy categories (66-69 %) and that few belonged within their most healthy categories (14-22 %). Agreement among profiling systems was moderate to good, with κ w values ranging from 0·49 to 0·69. Implementers offered fewer of the least healthy items (P<0·05) and these items had a better nutritional profile compared with items in non-implementing facilities. The policy outcomes of the three systems are likely to be similar, suggesting there may be scope to harmonize nutrient profiling systems at a national level to avoid unnecessary duplication and support food reformulation by industry.

  17. Energy demand and thermal comfort of HVAC systems with thermally activated building systems as a function of user profile

    Directory of Open Access Journals (Sweden)

    Pałaszyńska Katarzyna

    2017-01-01

    Full Text Available Thermally Activated Building Systems (TABS are a way to use building structure as a thermal energy storage. As a result, renewable energy sources may be used more efficiently. The paper presents numerical analysis of a HVAC system with TABS energy demand and indoor thermal comfort of a representative room in a non-residential building (governmental, commercial, educational. The purpose of analysis is to investigate the influence of a user profile on system performance. The time span of the analysis is one year – a typical meteorological year. The model was prepared using a generally accepted simulation tool – TRNSYS 17. The results help to better understand the interaction of a user profile with TABS. Therefore they are important for the development of optimal control algorithms for energy efficient buildings equipped with such systems.

  18. The losses at power grid caused by small nonlinear loads

    Directory of Open Access Journals (Sweden)

    Stevanović Dejan

    2013-01-01

    Full Text Available The difference between registered active power and spent unregistered power represents the losses at power grid. This paper treats problems related to losses caused by nonlinear loads connected to the power grid. In recent years the load profile of power consumers turned from energy-waster linear to energysaver but non-linear loads. The main cause of the losses appears due to the lack of adequate measurement equipment. Namely, common household power meters register only active energy, while power meters for industrial application register reactive energy as well. This approach does not follow the change of the enduser profile. Tendency of improving energy efficiency brought wide use of switching mode regulators and replace old incandescent light bulb with new energy saving lamps (CFL - compact fluorescent lamp, LED bulb. Therefore, the number of non-linear load drastically increased. Registering only active component of power at consumer’s side does not depict the real profile of the consumption. Therefore, in this paper we analyse and quantify the effects of nonlinear loads at power losses. As a result we suggest an efficient method for measuring the distortion component of power. The method relays on low-cost upgrade of commercial electronic power meters. The presented results of measurements on small non-linear loads confirm the proposed technique. Besides, they prove the importance of measuring all components of apparent power and justified their use in billing policy. The implemented set-up is based on power meter manufactured by EWG of Niš. [Projekat Ministarstva nauke Republike Srbije, br. TR32004

  19. Beam-scanning system for determination of beam profiles and form factors in merged-beam experiments

    International Nuclear Information System (INIS)

    Keyser, C.J.; Froelich, H.R.; Mitchell, J.B.A.; McGowan, J.W.

    1979-01-01

    A beam-scanning system for a merged electron-ion beam experiment is described. This system is used to determine the horizontal and vertical beam profiles and the form factors at three different locations along the axis of the beams. Design details of the wedge-shaped scanners and the electronic circuit for obtaining beam profiles and form factors are described. The form factor derivation for merged beams is given and an expression in terms of measured quantities is derived. (author)

  20. A Danish Profiling System

    DEFF Research Database (Denmark)

    Rosholm, Michael; Staghøj, Jonas; Svarer, Michael

    2006-01-01

    This paper describes the statistical model used for profiling new unemployed workers in Denmark. When a worker – during his or her first six months in unemployment – enters the employment office for the first time, this model predicts whether or not he or she will be unemployed for more than six ...

  1. SPSP Phase III Recruiting, Selecting, and Developing Secure Power Systems Professionals. Job Profiles

    Energy Technology Data Exchange (ETDEWEB)

    O' Neil, Lori Ross [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Conway, T. J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Tobey, D. H. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Greitzer, Frank L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Dalton, Angela C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Pusey, Portia K. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-03-01

    The Secure Power Systems Professional Phase III final report was released last year which an appendix of Job Profiles. This new report is that appendix broken out as a standalone document to assist utilities in recruiting and developing Secure Power Systems Professionals at their site.

  2. 12 CFR 370.8 - Systemic risk emergency special assessment to recover loss.

    Science.gov (United States)

    2010-01-01

    ... recover loss. 370.8 Section 370.8 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND STATEMENTS OF GENERAL POLICY TEMPORARY LIQUIDITY GUARANTEE PROGRAM § 370.8 Systemic risk emergency special... temporary liquidity guarantee program, the Corporation shall impose an emergency special assessment on...

  3. Persistent breather excitations in an ac-driven sine-Gordon system with loss

    International Nuclear Information System (INIS)

    Lomdahl, P.S.; Samuelsen, M.R.

    1986-01-01

    In a sine-Gordon system with loss and applied ac driver, a breather can be maintained as a persistent entrained oscillation if the driver is strong enough. The threshold field is determined by a perturbation method and compared to numerical experiments. Excellent agreement is found

  4. Analysis of pressure losses in the diffuser of a control valve

    Science.gov (United States)

    Turecký, Petr; Mrózek, Lukáš; Tajč, Ladislav; Kolovratník, Michal

    The pressure loss in the diffuser of a control valve is evaluated by using CFD computations. Pressure ratios and lifts of a cone for the recommended flow characteristics of an experimental turbine are considered. The pressure loss in a valve is compared with the pressure loss in a nozzle, i.e. the embodiment of the valve without a cone. Computations are carried out for the same mass flow. Velocity profiles are evaluated in both versions of computations. Comparison of computed pressure losses, with the loss evaluated by using relations for diffusers with the ideal velocity conditions in the input cross-section, is carried out.

  5. Analysis of pressure losses in the diffuser of a control valve

    Directory of Open Access Journals (Sweden)

    Turecký Petr

    2017-01-01

    Full Text Available The pressure loss in the diffuser of a control valve is evaluated by using CFD computations. Pressure ratios and lifts of a cone for the recommended flow characteristics of an experimental turbine are considered. The pressure loss in a valve is compared with the pressure loss in a nozzle, i.e. the embodiment of the valve without a cone. Computations are carried out for the same mass flow. Velocity profiles are evaluated in both versions of computations. Comparison of computed pressure losses, with the loss evaluated by using relations for diffusers with the ideal velocity conditions in the input cross-section, is carried out.

  6. Profile measurements of localized fast electrons and ions in TORE SUPRA

    International Nuclear Information System (INIS)

    Basiuk, V.; Roubin, J.P.; Becoulet, A.; Carrasco, J.; Martin, G.; Moreau, D.; Saoutic, B.

    1992-01-01

    The strong toroidal and poloidal anisotropy of the heat flux to the first wall of Tore Supra during additional heating has been related to suprathermal particle losses induced by the TF ripple. In this paper we describe a new system of electric collectors designed to diagnose these localized particles and we analyse measurements performed during LHCD, ICRH and NBI heating. The interaction of fast particles created by additional heating with the TF ripple perturbation in Tore Supra has been analyzed by a direct measurement of the localized particles. The good confinement region has been identified thanks to a peak in the measured current profiles and is in agreement with theory. During LHCD and ICRH, the global losses are weak but strongly anisotropic leading to hot spots at the wall. During ICRH, an ejection of fast ions by the sawteeth towards peripheral zones where they get lost in the ripple has been seen. This is a possible scenario of α particle losses in a reactor

  7. Choice of capillary electrophoresis systems for the impurity profiling of drugs

    NARCIS (Netherlands)

    Hilhorst, M.J; Somsen, G.W; de Jong, G.J.

    In order to develop a strategy for the impurity profiling of drugs, the possibilities of some capillary electrophoresis systems were investigated. A mixture containing a drug and some of its possible impurities has been used as a model problem. The test compounds were investigated by capillary zone

  8. Piloted Simulation Evaluation of a Model-Predictive Automatic Recovery System to Prevent Vehicle Loss of Control on Approach

    Science.gov (United States)

    Litt, Jonathan S.; Liu, Yuan; Sowers, Thomas S.; Owen, A. Karl; Guo, Ten-Huei

    2014-01-01

    This paper describes a model-predictive automatic recovery system for aircraft on the verge of a loss-of-control situation. The system determines when it must intervene to prevent an imminent accident, resulting from a poor approach. It estimates the altitude loss that would result from a go-around maneuver at the current flight condition. If the loss is projected to violate a minimum altitude threshold, the maneuver is automatically triggered. The system deactivates to allow landing once several criteria are met. Piloted flight simulator evaluation showed the system to provide effective envelope protection during extremely unsafe landing attempts. The results demonstrate how flight and propulsion control can be integrated to recover control of the vehicle automatically and prevent a potential catastrophe.

  9. Diagnosis System for Diabetic Retinopathy and Glaucoma Screening to Prevent Vision Loss

    Directory of Open Access Journals (Sweden)

    Siva Sundhara Raja DHANUSHKODI

    2014-03-01

    Full Text Available Aim: Diabetic retinopathy (DR and glaucoma are two most common retinal disorders that are major causes of blindness in diabetic patients. DR caused in retinal images due to the damage in retinal blood vessels, which leads to the formation of hemorrhages spread over the entire region of retina. Glaucoma is caused due to hypertension in diabetic patients. Both DR and glaucoma affects the vision loss in diabetic patients. Hence, a computer aided development of diagnosis system for Diabetic retinopathy and Glaucoma screening is proposed in this paper to prevent vision loss. Method: The diagnosis system of DR consists of two stages namely detection and segmentation of fovea and hemorrhages. The diagnosis system of glaucoma screening consists of three stages namely blood vessel segmentation, Extraction of optic disc (OD and optic cup (OC region and determination of rim area between OD and OC. Results: The specificity and accuracy for hemorrhages detection is found to be 98.47% and 98.09% respectively. The accuracy for OD detection is found to be 99.3%. This outperforms state-of-the-art methods. Conclusion: In this paper, the diagnosis system is developed to classify the DR and glaucoma screening in to mild, moderate and severe respectively.

  10. A REVIEW OF FINANCIAL REGULATIONS TO AVOID THE NATIONALISATION OF LOSSES IN THE BANKING SYSTEM

    Directory of Open Access Journals (Sweden)

    SORANA VĂTAVU

    2011-01-01

    Full Text Available This article investigates the regulations which should be applied in the financial system in order to minimize the losses. The subject is based on the banking policy of “privatisation of profits and nationalisation of losses” and it is debated mainly from trade articles point of view. Even when taxpayers do not agree, governments choose either to bailout influential banks or to cover their losses with a deposit insurance. Banks would take advantage of any opportunity to increase earnings, even in the insolvency stage, and thus certain regulations and limitations must be provided to minimize the moral hazard occurred. The most important problem that deepens financial regressions relates to the losses spillover effect on the worldwide economy, and although a perfect global banking model cannot be implemented, the paper suggests regulations which improve the financial systems.

  11. Connected Lighting Systems Efficiency Study$-$ PoE Cable Energy Losses, Part 1

    Energy Technology Data Exchange (ETDEWEB)

    Tuenge, Jason [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kelly, Karsten [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Poplawski, Michael [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2017-11-30

    First report in a study of the efficiency of connected lighting systems. The report summarizes the results of an exploratory study investigating power losses in Ethernet cables used between PoE switches and luminaires in PoE connected lighting systems. Testing was conducted at the Pacific Northwest National Laboratory (PNNL) Connected Lighting Test Bed in September 2017. The results were analyzed to explore the impact of cable selection on PoE lighting system energy efficiency, as well as the effectiveness of guidelines recently introduced by the American National Standards Institute (ANSI) C137 Lighting Systems Committee.

  12. Profiles of radiation power density in WEGA stellarator

    International Nuclear Information System (INIS)

    Zhang, D.; Otte, M.; Giannone, L.

    2005-01-01

    On the WEGA stellarator, a 12 channel bolometer camera has been used to measure the radiation power losses of the plasma, which is heated by ECR at 2.45 GHz with a maximum power of 26 kW. The typical electron temperatures achieved are around 10 eV. The bolometer is of the Au resistor type and is positioned on the mid-plane, viewing the plasma from the low-field side with a spatial resolution of about 6 cm. The viewing angle is opened to poloidally (±47 o ) and covers the whole cross-section. Angular profiles of radiation power density (emissivity) can be achieved using the measured fluxes to the channels, which are given by the integrals along the sight lines. Using Abel inversion with maximum entropy regularisation, radial profiles of emissivity could be obtained. It is found that the angular profile of emissivity depends on the magnetic configuration, the working gas (Ar, He) and the heating scenario. Peaked and hollow emissivity profiles have been obtained by using different types of heating antenna. By changing the magnetic configuration, strong edge radiation has been observed. The largest emissivity values are obtained in the upper SOL range of Ar-discharges. This edge radiation can be reduced by shifting the flux surfaces inwards or by changing their shape at the antenna. The reconstruction of the radial profile of the emissivity was carried out in the case of a peaked angular profile with minimum edge radiation. The total radiation power was estimated by linear extrapolation of the integrated radiation power in the viewing region to the torus volume. It is typically less than 30% of the ECRH input power, but depending on the ECRH input power, again the magnetic configuration, the working gas as well as the absolute field strength on the magnetic axis. Maximum radiation losses have been obtained around 0.6·B0, where B 0 =87.5 mT is the resonant field strength of the ECRH. No evidence for impurities was obtained from spectroscopic measurements, and thus the

  13. Classifications of Patterned Hair Loss: A Review.

    Science.gov (United States)

    Gupta, Mrinal; Mysore, Venkataram

    2016-01-01

    Patterned hair loss is the most common cause of hair loss seen in both the sexes after puberty. Numerous classification systems have been proposed by various researchers for grading purposes. These systems vary from the simpler systems based on recession of the hairline to the more advanced multifactorial systems based on the morphological and dynamic parameters that affect the scalp and the hair itself. Most of these preexisting systems have certain limitations. Currently, the Hamilton-Norwood classification system for males and the Ludwig system for females are most commonly used to describe patterns of hair loss. In this article, we review the various classification systems for patterned hair loss in both the sexes. Relevant articles were identified through searches of MEDLINE and EMBASE. Search terms included but were not limited to androgenic alopecia classification, patterned hair loss classification, male pattern baldness classification, and female pattern hair loss classification. Further publications were identified from the reference lists of the reviewed articles.

  14. Classifications of patterned hair loss: a review

    Directory of Open Access Journals (Sweden)

    Mrinal Gupta

    2016-01-01

    Full Text Available Patterned hair loss is the most common cause of hair loss seen in both the sexes after puberty. Numerous classification systems have been proposed by various researchers for grading purposes. These systems vary from the simpler systems based on recession of the hairline to the more advanced multifactorial systems based on the morphological and dynamic parameters that affect the scalp and the hair itself. Most of these preexisting systems have certain limitations. Currently, the Hamilton-Norwood classification system for males and the Ludwig system for females are most commonly used to describe patterns of hair loss. In this article, we review the various classification systems for patterned hair loss in both the sexes. Relevant articles were identified through searches of MEDLINE and EMBASE. Search terms included but were not limited to androgenic alopecia classification, patterned hair loss classification, male pattern baldness classification, and female pattern hair loss classification. Further publications were identified from the reference lists of the reviewed articles.

  15. Estimating forest structural characteristics using the airborne LiDAR scanning system and a near-real time profiling laser system

    Science.gov (United States)

    Zhao, Kaiguang

    LiDAR (Light Detection and Ranging) directly measures canopy vertical structures, and provides an effective remote sensing solution to accurate and spatially-explicit mapping of forest characteristics, such as canopy height and Leaf Area Index. However, many factors, such as large data volume and high costs for data acquisition, precludes the operational and practical use of most currently available LiDARs for frequent and large-scale mapping. At the same time, a growing need is arising for real-time remote sensing platforms, e.g., to provide timely information for urgent applications. This study aims to develop an airborne profiling LiDAR system, featured with on-the-fly data processing, for near real- or real-time forest inventory. The development of such a system involves implementing the on-board data processing and analysis as well as building useful regression-based models to relate LiDAR measurements with forest biophysical parameters. This work established a paradigm for an on-the-fly airborne profiling LiDAR system to inventory regional forest resources in real- or near real-time. The system was developed based on an existing portable airborne laser system (PALS) that has been previously assembled at NASA by Dr. Ross Nelson. Key issues in automating PALS as an on-the-fly system were addressed, including the design of an archetype for the system workflow, the development of efficient and robust algorithms for automatic data processing and analysis, the development of effective regression models to predict forest biophysical parameters from LiDAR measurements, and the implementation of an integrated software package to incorporate all the above development. This work exploited the untouched potential of airborne laser profilers for real-time forest inventory, and therefore, documented an initial step toward developing airborne-laser-based, on-the-fly, real-time, forest inventory systems. Results from this work demonstrated the utility and effectiveness of

  16. European securitization and biometric identification: the uses of genetic profiling.

    Science.gov (United States)

    Johnson, Paul; Williams, Robin

    2007-01-01

    The recent loss of confidence in textual and verbal methods for validating the identity claims of individual subjects has resulted in growing interest in the use of biometric technologies to establish corporeal uniqueness. Once established, this foundational certainty allows changing biographies and shifting category memberships to be anchored to unchanging bodily surfaces, forms or features. One significant source for this growth has been the "securitization" agendas of nation states that attempt the greater control and monitoring of population movement across geographical borders. Among the wide variety of available biometric schemes, DNA profiling is regarded as a key method for discerning and recording embodied individuality. This paper discusses the current limitations on the use of DNA profiling in civil identification practices and speculates on future uses of the technology with regard to its interoperability with other biometric databasing systems.

  17. Dexamethasone loaded nanoparticles exert protective effects against Cisplatin-induced hearing loss by systemic administration.

    Science.gov (United States)

    Sun, Changling; Wang, Xueling; Chen, Dongye; Lin, Xin; Yu, Dehong; Wu, Hao

    2016-04-21

    Ototoxicity is one of the most important adverse effects of cisplatin chemotherapy. As a common treatment of acute sensorineural hearing loss, systemic administration of steroids was demonstrated ineffective against cisplatin-induced hearing loss (CIHL) in published studies. The current study aimed to evaluate the potential protective effect of dexamethasone (DEX) encapsulated in polyethyleneglycol-coated polylactic acid (PEG-PLA) nanoparticles (DEX-NPs) against cisplatin-induced hearing loss following systemic administration. DEX was fabricated into PEG-PLA nanoparticles using emulsion and evaporation technique as previously reported. DEX or DEX-NPs was administered intraperitoneally to guinea pigs 1h before cisplatin administration. Auditory brainstem response (ABR) threshold shifts were measured at four frequencies (4, 8, 16, and 24kHz) 1 day before and three days after cisplatin injection. Cochlear morphology was examined to evaluate inner ear injury induced by cisplatin exposure. A single dose of DEX-NPs 1h before cisplatin treatment resulted in a significant preservation of the functional and structural properties of the cochlea, which was equivalent to the effect of multidose (3 days) DEX injection. In contrast, no significant protective effect was observed by single dose injection of DEX. The results of histological examination of the cochleae were consistent with the functional measurements. In conclusion, a single dose DEX-NPs significantly attenuated cisplatin ototoxicity in guinea pigs after systemic administration at both histological and functional levels indicating the potential therapeutic benefits of these nanoparticles for enhancing the delivery of DEX in acute sensorineural hearing loss. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  18. Heterogeneity of Systemic Oxidative Stress Profiles in COPD: A Potential Role of Gender

    Directory of Open Access Journals (Sweden)

    Jonathan Maury

    2015-01-01

    Full Text Available Oxidative stress (OS plays a key role in the muscle impairment and exercise capacity of COPD patients. However, the literature reveals that systemic OS markers show great heterogeneity, which may hinder the prescription of effective antioxidant supplementation. This study therefore aimed to identify OS markers imbalance of COPD patients, relative to validated normal reference values, and to investigate the possibility of systemic OS profiles. We measured systemic enzymatic/nonenzymatic antioxidant and lipid peroxidation (LP levels in 54 stable COPD patients referred for a rehabilitation program. The main systemic antioxidant deficits in these patients concerned vitamins and trace elements. Fully 89% of the COPD patients showed a systemic antioxidant imbalance which may have caused the elevated systemic LP levels in 69% of them. Interestingly, two patient profiles (clusters 3 and 4 had a more elevated increase in LP combined with increased copper and/or decreased vitamin C, GSH, and GPx. Further analysis revealed that the systemic LP level was higher in COPD women and associated with exercise capacity. Our present data therefore support future supplementations with antioxidant vitamins and trace elements to improve exercise capacity, but COPD patients will probably show different positive responses.

  19. PROFIL-360 high resolution steam generator tube profilometry system

    International Nuclear Information System (INIS)

    Glass, S.W.

    1985-01-01

    A high-resolution profilometry system, PROFIL 360, has been developed to assess the condition of steam generator tubes and rapidly produce the data to evaluate the potential for developing in-service leaks. The probe has an electromechanical sensor in a rotating head. This technique has been demonstrated in the field, saving tubes that would have been plugged with the go-gauge criterion and indicating plugging other high-risk candidates that might otherwise not have been removed from service

  20. Profil-360 high resolution steam generator tube profilometry system

    International Nuclear Information System (INIS)

    Glass, S.W.

    1985-01-01

    A high-resolution profilometry system, PROFIL 360, has been developed to assess the condition of steam generator tubes and rapidly produce the data to evaluate the potential for developing in-service leaks. The probe has an electromechanical sensor in a rotating head. This technique has been demonstrated in the field, saving tubes that would have been plugged with the go-gauge criterion and indicating plugging other high-risk candidates that might otherwise not have been removed from service

  1. Enhanced GSA-Based Optimization for Minimization of Power Losses in Power System

    Directory of Open Access Journals (Sweden)

    Gonggui Chen

    2015-01-01

    Full Text Available Gravitational Search Algorithm (GSA is a heuristic method based on Newton’s law of gravitational attraction and law of motion. In this paper, to further improve the optimization performance of GSA, the memory characteristic of Particle Swarm Optimization (PSO is employed in GSAPSO for searching a better solution. Besides, to testify the prominent strength of GSAPSO, GSA, PSO, and GSAPSO are applied for the solution of optimal reactive power dispatch (ORPD of power system. Conventionally, ORPD is defined as a problem of minimizing the total active power transmission losses by setting control variables while satisfying numerous constraints. Therefore ORPD is a complicated mixed integer nonlinear optimization problem including many constraints. IEEE14-bus, IEEE30-bus, and IEEE57-bus test power systems are used to implement this study, respectively. The obtained results of simulation experiments using GSAPSO method, especially the power loss reduction rates, are compared to those yielded by the other modern artificial intelligence-based techniques including the conventional GSA and PSO methods. The results presented in this paper reveal the potential and effectiveness of the proposed method for solving ORPD problem of power system.

  2. First experience with the new Coupling Loss Induced Quench system

    CERN Document Server

    Ravaioli, E; Dudarev, A V; Kirby, G; Sperin, K A; ten Kate, H H J; Verweij, A P

    2014-01-01

    New-generation high-field superconducting magnets pose a challenge relating to the protection of the coil winding pack in the case of a quench. The high stored energy per unit volume calls for a very efficient quench detection and fast quench propagation in order to avoid damage due to overheating. A new protection system called Coupling-Loss Induced Quench (CLIQ) was recently, developed and tested at CERN. This method provokes a fast change in the magnet transport current by means of a capacitive discharge. The resulting change in the local magnetic field induces inter-filament and inter-strand coupling losses which heat up the superconductor and eventually initiate a quench in a large fraction of the coil winding pack. The method is extensively tested on a Nb-Ti single-wire test solenoid magnet in the CERN Cryogenic Laboratory in order to assess its performance, optimize its operating parameters, and study new electrical configurations. Each parameter is thoroughly analyzed and its impact on the quench effi...

  3. Genome-wide analysis of immune system genes by EST profiling

    Science.gov (United States)

    Giallourakis, Cosmas; Benita, Yair; Molinie, Benoit; Cao, Zhifang; Despo, Orion; Pratt, Henry E.; Zukerberg, Lawrence R.; Daly, Mark J.; Rioux, John D.; Xavier, Ramnik J.

    2013-01-01

    Profiling studies of mRNA and miRNA, particularly microarray-based studies, have been extensively used to create compendia of genes that are preferentially expressed in the immune system. In some instances, functional studies have been subsequently pursued. Recent efforts such as ENCODE have demonstrated the benefit of coupling RNA-Seq analysis with information from expressed sequence tags (ESTs) for transcriptomic analysis. However, the full characterization and identification of transcripts that function as modulators of human immune responses remains incomplete. In this study, we demonstrate that an integrated analysis of human ESTs provides a robust platform to identify the immune transcriptome. Beyond recovering a reference set of immune-enriched genes and providing large-scale cross-validation of previous microarray studies, we discovered hundreds of novel genes preferentially expressed in the immune system, including non-coding RNAs. As a result, we have established the Immunogene database, representing an integrated EST “road map” of gene expression in human immune cells, which can be used to further investigate the function of coding and non-coding genes in the immune system. Using this approach, we have uncovered a unique metabolic gene signature of human macrophages and identified PRDM15 as a novel overexpressed gene in human lymphomas. Thus we demonstrate the utility of EST profiling as a basis for further deconstruction of physiologic and pathologic immune processes. PMID:23616578

  4. Review of the Operability for the Components Under the Loss of the HVAC System of the Pump Room

    International Nuclear Information System (INIS)

    Hwang Mee Jeong; Yoon, Churl; Yang, Joon Eon; Park, Joo Hwan

    2005-01-01

    In this paper, we estimated the temperature of the pump rooms and reviewed the operability of the components under the loss of the HVAC (Heating, Ventilation, and Air Condition) system. The issues relevant to the HVAC system in the PSA (Probabilistic Safety Assessment) FT (Fault Tree) model are as follows: does the loss of the HVAC system bring about a function failure of other components?. Can the operator take action to reduce the temperature of the room in case of a HVAC function failure?. At present we do not know whether a component will lose its function or not under the loss of the HVAC. ASME Standard describes that a recovery action can be credited if the related recovery action is included in the procedure or there are similar recovery experiences in the plant. However, there is no description about the recovery action of the HVAC in the EOP (Emergency Operation Procedure) of the UCN3, 4 under the situation of a loss of the HVAC. Even though we consider this assumption positively, it would be limited to the rooms such as the Switchgear Room, Inverter Room, and Main Control Room etc. where a real recovery action can be performed easily. However, if we consider the HVAC failure in the PSA FT model according to the above background, the problem is that the unavailability induced from the loss of a HVAC is highly unrealistically. From a viewpoint of the PSA, it is not true that the related system always fails even though the HVAC system fails. Therefore, we reviewed the necessity of the HVAC model through the identification of the operable temperature of the components' within the pump room and the change of the temperature of the pump room under the situation of a loss of the HVAC system

  5. A Comparison of Clinical Outcomes with Regular- and Low-Profile Totally Implanted Central Venous Port Systems

    International Nuclear Information System (INIS)

    Teichgraeber, Ulf Karl-Martin; Steitparth, Florian; Cho, Chie Hee; Benter, Thomas; Gebauer, Bernhard

    2009-01-01

    The purpose of this study was to evaluate whether low-profile totally implanted central venous port systems can reduce the late complication of skin perforation. Forty patients (age, 57 ± 13 years; 22 females, 18 males) were randomized for the implantation of a low-profile port system, and another 40 patients (age, 61 ± 14 years; 24 females, 16 males) received a regular port system as control group. Indications for port catheter implantation were malignant disease requiring chemotherapy. All port implantations were performed in the angiography suite using sonographically guided central venous puncture and fluoroscopic guidance of the catheter placement. Procedure time, number of complications (procedure-related immediate, early, and late complications), and number of explantations were assessed. Follow-up was performed for 6 months. All port implantations were successfully completed in both study groups. There were two incidents of skin perforation observed in the control group. One skin perforation occurred 13 weeks and the other 16 weeks after port implantation (incidence, 5%) in patients with regular-profile port systems. Two infections were observed, one port infection in each study group. Both infections were characterized as catheter-related infections (infection rate: 0.15 catheter-related infections per 1000 catheter days). In conclusion, low-profile port systems can be placed as safely as traditional chest ports and reduce the risk of developing skin perforations, which occurs when the port system is too tight within the port pocket.

  6. The circulating cell-free microrna profile in systemic sclerosis is distinct from both healthy controls and Systemic Lupus Erythematosus

    DEFF Research Database (Denmark)

    Steen, S. O.; Iversen, L. V.; Carlsen, A. L.

    2015-01-01

    Objective. To evaluate the expression profile of cell-free circulating microRNA (miRNA) in systemic sclerosis (SSc), healthy controls (HC), and systemic lupus erythematosus (SLE). Methods. Total RNA was purified from plasma and 45 different, mature miRNA were measured using quantitative PCR assays...

  7. DG Allocation Based on Reliability, Losses and Voltage Sag Considerations: an expert system approach

    Directory of Open Access Journals (Sweden)

    Sahar Abdel Moneim Moussa

    2017-03-01

    Full Text Available Expert System (ES as a branch of Artificial Intelligence (AI methodology can potentially help in solving complicated power system problems. This may be more appropriate methodology than conventional optimization techniques when contradiction between objectives appears in reaching the optimum solution. When this contradiction is the hindrance in reaching the required system operation through the application of traditional methods ES can give a hand in such case. In this paper, the  knowledge- based ES technique is proposed to reach near-optimum solution which is further directed to the optimum solution through particle swarm optimization (PSO technique. This idea is known as Hybrid-Expert-System (HES. The proposed idea is used in getting the optimum allocation of a number of distributed generation (DG units on Distribution System (DS busbars taking into consideration three issues; reliability, voltage sag, and line losses. Optimality is assessed on the economic basis by calculating money benefits (or losses resulting from DG addition considering the three aforementioned issues. The effectiveness of the proposed technique is ascertained through example.

  8. Systemic Administration of Allogeneic Mesenchymal Stem Cells Does Not Halt Osteoporotic Bone Loss in Ovariectomized Rats.

    Directory of Open Access Journals (Sweden)

    Shuo Huang

    Full Text Available Mesenchymal stem cells (MSCs have innate ability to self-renew and immunosuppressive functions, and differentiate into various cell types. They have become a promising cell source for treating many diseases, particular for bone regeneration. Osteoporosis is a common metabolic bone disorder with elevated systemic inflammation which in turn triggers enhanced bone loss. We hypothesize that systemic infusion of MSCs may suppress the elevated inflammation in the osteoporotic subjects and slow down bone loss. The current project was to address the following two questions: (1 Will a single dose systemic administration of allogenic MSCs have any effect on osteoporotic bone loss? (2 Will multiple administration of allogenic MSCs from single or multiple donors have similar effect on osteoporotic bone loss? 18 ovariectomized (OVX rats were assigned into 3 groups: the PBS control group, MSCs group 1 (receiving 2x106 GFP-MSCs at Day 10, 46, 91 from the same donor following OVX and MSCs group 2 (receiving 2x106 GFP-MSCs from three different donors at Day 10, 46, 91. Examinations included Micro-CT, serum analysis, mechanical testing, immunofluorescence staining and bone histomorphometry analysis. Results showed that BV/TV at Day 90, 135, BMD of TV and trabecular number at Day 135 in the PBS group were significantly higher than those in the MSCs group 2, whereas trabecular spacing at Day 90, 135 was significantly smaller than that in MSCs group 2. Mechanical testing data didn't show significant difference among the three groups. In addition, the ELISA assay showed that level of Rantes in serum in MSCs group 2 was significantly higher than that of the PBS group, whereas IL-6 and IL-10 were significantly lower than those of the PBS group. Bone histomorphometry analysis showed that Oc.S/BS and Oc.N/BS in the PBS group were significant lower than those in MSCs group 2; Ob.S/BS and Ob.N/BS did not show significant difference among the three groups. The current study

  9. Wind-driven angular momentum loss in binary systems. I - Ballistic case

    Science.gov (United States)

    Brookshaw, Leigh; Tavani, Marco

    1993-01-01

    We study numerically the average loss of specific angular momentum from binary systems due to mass outflow from one of the two stars for a variety of initial injection geometries and wind velocities. We present results of ballistic calculations in three dimensions for initial mass ratios q of the mass-losing star to primary star in the range q between 10 exp -5 and 10. We consider injection surfaces close to the Roche lobe equipotential surface of the mass-losing star, and also cases with the mass-losing star underfilling its Roche lobe. We obtain that the orbital period is expected to have a negative time derivative for wind-driven secular evolution of binaries with q greater than about 3 and with the mass-losing star near filling its Roche lobe. We also study the effect of the presence of an absorbing surface approximating an accretion disk on the average final value of the specific angular momentum loss. We find that the effect of an accretion disk is to increase the wind-driven angular momentum loss. Our results are relevant for evolutionary models of high-mass binaries and low-mass X-ray binaries.

  10. Analysis of three loss-of-flow accidents in the first wall cooling system of NET/ITER

    International Nuclear Information System (INIS)

    Komen, E.M.J.; Koning, H.

    1993-05-01

    This report presents the thermal-hydraulic analysis of three Loss-of-Flow Accidents (LOFAs) in the first wall cooling system of the Next European Torus (NET) design or the International Thermonuclear Experimental Reactor (ITER) design. The LOFAs considered result from a loss of the forced coolant flow caused by a loss of electrical power for the recirculation pump in the primary circuit. The analyses have been performed using the thermal-hydraulic system analysis code RELAP5/MOD3. In the analyses, special attention has been paid to the transient thermal-hydraulic behaviour of the cooling system and the temperature development in the first wall. In the LOFA case without plasma shutdown, melting starts in the first wall about 150 s after accident initiation. In the LOFA case with delayed plasma shutdown, melting starts in the first wall when the plasma shutdown is initiated later than about 110 s after accident initiation. Melting does not occur in the first wall during a LOFA with prompt plasma scram. (orig.)

  11. Periodontal profile class is associated with prevalent diabetes, coronary heart disease, stroke, and systemic markers of C-reactive protein and interleukin-6.

    Science.gov (United States)

    Beck, James D; Moss, Kevin L; Morelli, Thiago; Offenbacher, Steven

    2018-02-01

    This paper focuses on the Periodontal Profile Class (PPC) System that may be more informative and representative of periodontitis phenotypes than current case definitions of periodontitis. This study illustrates the unique aspects of the PPC compared with other periodontal indices for studying associations between periodontal disease and prevalent systemic conditions. We computed odds ratios and 95% confidence intervals to compare associations between periodontal disease and prevalent systemic conditions using our new PPC and two traditional indices. We used the Bayesian Information Criterion (BIC) to determine the fit of the model and the magnitude of the contribution attributable to periodontal disease beyond traditional risk factors. The Atherosclerosis Risk in Communities (ARIC) Study (1996-1998) results were compared with results from the combined National Health and Nutrition Examination Survey 2009-2014 datasets. In the ARIC Study, high gingival inflammation, tooth loss, severe tooth loss, and severe disease PPC components were significantly associated with diabetes, coronary heart disease (CHD), high-sensitivity C-reactive protein, and interleukin (IL)-6, while only severe disease was associated with stroke. Severe disease was associated with CHD using the Centers for Disease Control/American Academy of Periodontology index, and the European Periodontal index was associated with CHD and IL-6. The addition of the PPC to traditional variables associated with prevalent diabetes, stroke, CHD, and systemic measures of inflammation resulted in very strong improvement of the overall models, while the traditional indices were less likely to be associated and, if present, the associations were weaker. The PPC system provides specific insight into the individuals and periodontal characteristics of the phenotype that are associated with systemic conditions that may be useful in designing treatment interventions. © 2018 American Academy of Periodontology.

  12. Provider Profiling: A Population Health Improvement Tool for the Southeast Military Health System

    National Research Council Canada - National Science Library

    Pemberton, Phillip

    1999-01-01

    ...). Profiling with Provider Perspectives, a Primary Care Management Tool, provides the SEMHS with a standardized performance measurement system that offers feedback in a user friendly and non-threatening format...

  13. Integration of polystyrene microlenses with both convex and concave profiles in a polymer-based microfluidic system

    KAUST Repository

    Fan, Yiqiang

    2013-12-20

    This paper reports a new technique of fabricating polystyrene microlenses with both convex and concave profiles that are integrated in polymer-based microfluidic system. The polystyrene microlenses, or microlens array, are fabricated using the free-surface thermal compression molding method. The laser fabricated poly(methyl methacrylate) (PMMA) sheet is used as the mold for the thermal compression molding process. With different surface treatment methods of the PMMA mold, microlenses with either convex or concave profiles could be achieved during the thermal molding process. By integrating the microlenses in the microfluidic systems, observing the flow inside the microchannels is easier. This new technique is rapid, low cost, and it does not require cleanroom facilities. Microlenses with both convex and concave profiles can be easily fabricated and integrated in microfluidic system with this technique. © 2013 Springer-Verlag Berlin Heidelberg.

  14. [Intractable diarrhoea and severe weight loss by roflumilast].

    Science.gov (United States)

    Horna, Oihana; Toyas, Carla

    2013-08-04

    Roflumilast is a recently marketed drug, indicated for maintenance treatment of severe chronic obstructive pulmonary disease associated with chronic bronchitis in adult patients with a history of frequent exacerbations as add on to bronchodilator treatment. The safety data of this drug have always been subjected to controversy and concerns. The Food and Drug Administration rejected the drug after the first evaluation, asking the company to clarify the adverse reactions during the investigation process, the European Medicines Agency approved the drug including a Risk Management Plan, designed to promote a safe use of the drug. During the first months after the marketing process, the Spanish Pharmacovigilance System has already been acquainted of several adverse events notifications; therefore, these patients may be closely monitored, mainly because of digestive and psychiatric disorders. Here we report the case of a female patient who showed a serious digestive clinical profile and a severe weight loss, more than 25% of her initial weight, when a treatment with roflumilast was started. The suspicion of a side effect as the cause of the reported clinical profile and its resolution required 3 hospital admissions. Copyright © 2013 Elsevier España, S.L. All rights reserved.

  15. Impact of Next Generation District Heating Systems on Distribution Network Heat Losses: A Case Study Approach

    Science.gov (United States)

    Li, Yu; Rezgui, Yacine

    2018-01-01

    District heating (DH) is a promising energy pathway to alleviate environmental negative impacts induced by fossil fuels. Improving the performance of DH systems is one of the major challenges facing its wide adoption. This paper discusses the heat losses of the next generation DH based on the constructed Simulink model. Results show that lower distribution temperature and advanced insulation technology greatly reduce network heat losses. Also, the network heat loss can be further minimized by a reduction of heat demand in buildings.

  16. Evaluation of Losses Of Cold Energy of Cryogen Products in The Transport Systems

    Science.gov (United States)

    Uglanov, Dmitry; Sarmin, Dmitry; Tsapkova, Alexandra; Burdina, Yana

    2017-12-01

    At present, there are problems of energy saving in various areas of human life and in power complexes of industrial plants. One possible solution to the problem of increasing energy efficiency is the use of liquefied natural gas and its cold energy. Pipelines for fuel or gas supply in cryogen supply systems have different length depending on the mutual position of storage and cryogen consumption devices relatively to a start construction. Cryogen supply and transport systems include a lot of fittings of different assortment. Reservoirs can be installed on different elevation points. To reduce heat inleak and decrease cold energy of cryogen product different kinds of thermal insulation are used. Cryogen pipelines provide required operation conditions of storage and gasifying systems. The aim of the thermal calculation of cryogen transport and supply systems is to define the value of cryogen heat. In this paper it is shown values of cryogen temperature rise due to heat inleaks at cryogen’s transfer along transport systems for ethane, methane, oxygen and nitrogen were calculated. Heat inleaks also due to hydraulic losses were calculated. Specific losses of cold energy of cryogen product for laminar and turbulent flow were calculated. Correspondences of temperature rise, critical pipeline’s length and Reynolds number were defined for nitrogen, argon, methane and oxygen.

  17. Cardiac Autonomic Nervous System Activation and Metabolic Profile in Young Children : The ABCD Study

    NARCIS (Netherlands)

    Vrijkotte, Tanja G M; van den Born, Bert-Jan H; Hoekstra, Christine M C A; Gademan, Maaike G J; van Eijsden, Manon; de Rooij, Susanne R; Twickler, Marcel T B

    2015-01-01

    BACKGROUND: In adults, increased sympathetic and decreased parasympathetic nervous system activity are associated with a less favorable metabolic profile. Whether this is already determined at early age is unknown. Therefore, we aimed to assess the association between autonomic nervous system

  18. Rat brain sagittal organotypic slice cultures as an ex vivo dopamine cell loss system.

    Science.gov (United States)

    McCaughey-Chapman, Amy; Connor, Bronwen

    2017-02-01

    Organotypic brain slice cultures are a useful tool to study neurological function as they provide a more complex, 3-dimensional system than standard 2-dimensional in vitro cell cultures. Building on a previously developed mouse brain slice culture protocol, we have developed a rat sagittal brain slice culture system as an ex vivo model of dopamine cell loss. We show that rat brain organotypic slice cultures remain viable for up to 6 weeks in culture. Using Fluoro-Gold axonal tracing, we demonstrate that the slice 3-dimensional cytoarchitecture is maintained over a 4 week culturing period, with particular focus on the nigrostriatal pathway. Treatment of the cultures with 6-hydroxydopamine and desipramine induces a progressive loss of Fluoro-Gold-positive nigral cells with a sustained loss of tyrosine hydroxylase-positive nigral cells. This recapitulates the pattern of dopaminergic degeneration observed in the rat partial 6-hydroxydopamine lesion model and, most importantly, the progressive pathology of Parkinson's disease. Our slice culture platform provides an advance over other systems, as we demonstrate for the first time 3-dimensional cytoarchitecture maintenance of rat nigrostriatal sagittal slices for up to 6 weeks. Our ex vivo organotypic slice culture system provides a long term cellular platform to model Parkinson's disease, allowing for the elucidation of mechanisms involved in dopaminergic neuron degeneration and the capability to study cellular integration and plasticity ex vivo. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. Global Profiling and Novel Structure Discovery Using Multiple Neutral Loss/Precursor Ion Scanning Combined with Substructure Recognition and Statistical Analysis (MNPSS): Characterization of Terpene-Conjugated Curcuminoids in Curcuma longa as a Case Study.

    Science.gov (United States)

    Qiao, Xue; Lin, Xiong-hao; Ji, Shuai; Zhang, Zheng-xiang; Bo, Tao; Guo, De-an; Ye, Min

    2016-01-05

    To fully understand the chemical diversity of an herbal medicine is challenging. In this work, we describe a new approach to globally profile and discover novel compounds from an herbal extract using multiple neutral loss/precursor ion scanning combined with substructure recognition and statistical analysis. Turmeric (the rhizomes of Curcuma longa L.) was used as an example. This approach consists of three steps: (i) multiple neutral loss/precursor ion scanning to obtain substructure information; (ii) targeted identification of new compounds by extracted ion current and substructure recognition; and (iii) untargeted identification using total ion current and multivariate statistical analysis to discover novel structures. Using this approach, 846 terpecurcumins (terpene-conjugated curcuminoids) were discovered from turmeric, including a number of potentially novel compounds. Furthermore, two unprecedented compounds (terpecurcumins X and Y) were purified, and their structures were identified by NMR spectroscopy. This study extended the application of mass spectrometry to global profiling of natural products in herbal medicines and could help chemists to rapidly discover novel compounds from a complex matrix.

  20. Towards a slow extraction system for the TRIUMF Kaon factory extender ring with 0.1% losses

    International Nuclear Information System (INIS)

    Wienands, U.; Servranckx, R.V.

    1988-03-01

    In order to reduce extraction losses a modified third-integral slow extraction system is proposed using a 0.5 m long and 10 μm thin electrostatic preseptum. Various factors limiting the extraction efficiency are investigated, and the losses are estimated to be as low as 0.2%. The extracted beam emittance is found to be about 0.2 π mm-mrad for achromatic extraction. For chromatic extraction a reduction in momentum width of the extracted beam by a factor of 2.5 will result in an extracted momentum bite of less than 30 MeV/c FWHM. This figure is limited by emittance blow-up due to synchrotron oscillations, which in turn increases extraction losses. Following the analytical estimate of the performance of the extraction system, simulation results are shown

  1. Application of Electromagnetic Induction to Monitor Changes in Soil Electrical Conductivity Profiles in Arid Agriculture

    KAUST Repository

    Jadoon, K.Z.

    2015-09-06

    In this research, multi-configuration electromagnetic induction (EMI) measurements were conducted in a corn field to estimate variation in soil electrical conductivity profiles in the roots zone. Electromagnetic forward model based on the full solution of Maxwell\\'s equation was used to simulate the apparent electrical conductivity measured with EMI system (the CMD mini-Explorer). Joint inversion of multi-configuration EMI measurements were performed to estimate the vertical soil electrical conductivity profiles. The inversion minimizes the misfit between the measured and modeled soil apparent electrical conductivity by DiffeRential Evolution Adaptive Metropolis (DREAM) algorithm, which is based on Bayesain approach. Results indicate that soil electrical conductivity profiles have low values close to the corn plants, which indicates loss of soil moisture due to the root water uptake. These results offer valuable insights into future potential and emerging challenges in the development of joint analysis of multi-configuration EMI measurements to retrieve effective soil electrical conductivity profiles.

  2. Demand side management using profile steering

    NARCIS (Netherlands)

    Gerards, Marco Egbertus Theodorus; Toersche, Hermen; Hoogsteen, Gerwin; van der Klauw, Thijs; Hurink, Johann L.; Smit, Gerardus Johannes Maria

    2015-01-01

    Many Demand Side Management (DSM) approaches use energy prices as steering signals. This paper shows that such steering signals may result in power quality problems and high losses. As an alternative, this paper proposes to use desired (e.g., flat) power profiles as steering signals and presents an

  3. Design and Development of a Diagnostics Client for a Beam Loss Measurement System at CERN

    CERN Document Server

    Angelogiannopoulos, Emmanouil; Jackson, Stephen

    The European Organization for Nuclear Research, known as CERN, is one of the biggest research centers in the field of particle physics. Its main function is to provide particle accelerators and other infrastructure needed for high energy physics research. Particles are accelerated through a complex of accelerators and are brought into collision, in order to study the fundamental elements of matter and the forces acting between them. Of course, such complex and expensive machines need control and protection. For that purpose, a variety of different systems -hardware and/or software- is needed. One such system is the Beam Loss Monitoring (BLM) system of an accelerator. This kind of system is designed for measuring beam losses around an accelerator. An appropriate design of the BLM system and an appropriate location of the monitors enable a wide field of very useful beam diagnostics and machine protection possibilities. This thesis focuses on the design and development of a client application, which is realized ...

  4. Flood Damage and Loss Estimation for Iowa on Web-based Systems using HAZUS

    Science.gov (United States)

    Yildirim, E.; Sermet, M. Y.; Demir, I.

    2016-12-01

    Importance of decision support systems for flood emergency response and loss estimation increases with its social and economic impacts. To estimate the damage of the flood, there are several software systems available to researchers and decision makers. HAZUS-MH is one of the most widely used desktop program, developed by FEMA (Federal Emergency Management Agency), to estimate economic loss and social impacts of disasters such as earthquake, hurricane and flooding (riverine and coastal). HAZUS used loss estimation methodology and implements through geographic information system (GIS). HAZUS contains structural, demographic, and vehicle information across United States. Thus, it allows decision makers to understand and predict possible casualties and damage of the floods by running flood simulations through GIS application. However, it doesn't represent real time conditions because of using static data. To close this gap, an overview of a web-based infrastructure coupling HAZUS and real time data provided by IFIS (Iowa Flood Information System) is presented by this research. IFIS is developed by the Iowa Flood Center, and a one-stop web-platform to access community-based flood conditions, forecasts, visualizations, inundation maps and flood-related data, information, and applications. Large volume of real-time observational data from a variety of sensors and remote sensing resources (radars, rain gauges, stream sensors, etc.) and flood inundation models are staged on a user-friendly maps environment that is accessible to the general public. Providing cross sectional analyses between HAZUS-MH and IFIS datasets, emergency managers are able to evaluate flood damage during flood events easier and more accessible in real time conditions. With matching data from HAZUS-MH census tract layer and IFC gauges, economical effects of flooding can be observed and evaluated by decision makers. The system will also provide visualization of the data by using augmented reality for

  5. An assessment of the ECMWF tropical cyclone ensemble forecasting system and its use for insurance loss predictions

    Science.gov (United States)

    Aemisegger, F.; Martius, O.; Wüest, M.

    2010-09-01

    Tropical cyclones (TC) are amongst the most impressive and destructive weather systems of Earth's atmosphere. The costs related to such intense natural disasters have been rising in recent years and may potentially continue to increase in the near future due to changes in magnitude, timing, duration or location of tropical storms. This is a challenging situation for numerical weather prediction, which should provide a decision basis for short term protective measures through high quality medium range forecasts on the one hand. On the other hand, the insurance system bears great responsibility in elaborating proactive plans in order to face these extreme events that individuals cannot manage independently. Real-time prediction and early warning systems are needed in the insurance sector in order to face an imminent hazard and minimise losses. Early loss estimates are important in order to allocate capital and to communicate to investors. The ECMWF TC identification algorithm delivers information on the track and intensity of storms based on the ensemble forecasting system. This provides a physically based framework to assess the uncertainty in the forecast of a specific event. The performance of the ECMWF TC ensemble forecasts is evaluated in terms of cyclone intensity and location in this study and the value of such a physically-based quantification of uncertainty in the meteorological forecast for the estimation of insurance losses is assessed. An evaluation of track and intensity forecasts of hurricanes in the North Atlantic during the years 2005 to 2009 is carried out. Various effects are studied like the differences in forecasts over land or sea, as well as links between storm intensity and forecast error statistics. The value of the ECMWF TC forecasting system for the global re-insurer Swiss Re was assessed by performing insurance loss predictions using their in-house loss model for several case studies of particularly devastating events. The generally known

  6. The extent and pathways of nitrogen loss in turfgrass systems: Age impacts.

    Science.gov (United States)

    Chen, Huaihai; Yang, Tianyou; Xia, Qing; Bowman, Daniel; Williams, David; Walker, John T; Shi, Wei

    2018-05-11

    Nitrogen loss from fertilized turf has been a concern for decades, with most research focused on inorganic (NO 3 - ) leaching. The present work examined both inorganic and organic N species in leachate and soil N 2 O emissions from intact soil cores of a bermudagrass chronosequence (1, 15, 20, and 109 years old) collected in both winter and summer. Measurements of soil N 2 O emissions were made daily for 3 weeks, while leachate was sampled once a week. Four treatments were established to examine the impacts of fertilization and temperature: no N, low N at 30 kg N ha -1 , and high N at 60 kg N ha -1 , plus a combination of high N and temperature (13 °C in winter or 33 °C in summer compared to the standard 23 °C). Total reactive N loss generally showed a "cup" pattern of turf age, being lowest for the 20 years old. Averaged across all intact soil cores sampled in winter and summer, organic N leaching accounted for 51% of total reactive N loss, followed by inorganic N leaching at 41% and N 2 O-N efflux at 8%. Proportional loss among the fractions varied with grass age, season, and temperature and fertilization treatments. While high temperature enhanced total reactive N loss, it had little influence on the partitioning of loss among dissolved organic N, inorganic N and N 2 O-N when C availability was expected to be high in summer due to rhizodeposition and root turnover. This effect of temperature was perhaps due to higher microbial turnover in response to increased C availability in summer. However when C availability was low in winter, warming might mainly affect microbial growth efficiency and therefore partitioning of N. This work provides a new insight into the interactive controls of warming and substrate availability on dissolved organic N loss from turfgrass systems. Copyright © 2018 Elsevier B.V. All rights reserved.

  7. [Effects of poplar-amaranth intercropping system on the soil nitrogen loss under different nitrogen applying levels].

    Science.gov (United States)

    Chu, Jun; Xue, Jian-Hui; Wu, Dian-Ming; Jin, Mei-Juan; Wu, Yong-Bo

    2014-09-01

    Characteristics of soil nitrogen loss were investigated based on field experiments in two types of poplar-amaranth intercropping systems (spacing: L1 2 m x 5 m, L2 2 m x 15 m) with four N application rates, i. e., 0 (N1), 91 (N2), 137 (N3) and 183 (N4) kg · hm(-2). The regulation effects on the soil surface runoff, leaching loss and soil erosion were different among the different types of intercropping systems: L1 > L2 > L3 (amaranth monocropping). Compared with the amaranth monocropping, the soil surface runoff rates of L1 and L2 decreased by 65.1% and 55.9%, the soil leaching rates of L1 and L2 with a distance of 0.5 m from the poplar tree row de- creased by 30.0% and 28.9%, the rates with a distance of 1. 5 m decreased by 25. 6% and 21.9%, and the soil erosion rates decreased by 65.0% and 55.1%, respectively. The control effects of two intercropping systems on TN, NO(3-)-N and NH(4+)-N in soil runoff and leaching loss were in the order of L1 > L2 > L3. Compared with the amaranth monocropping, TN, NO(3-)-N and NH(4+)-N loss rates in soil runoff of L1 decreased by 62.9%, 45.1% and 69.2%, while the loss rates of L2 decreased by 23.4%, 6.9% and 46.2% under N1 (91 kg · hm(-2)), respectively. High- er tree-planting density and closer positions to the polar tree row were more effective on controlling the loss rates of NO(3-)-N and NH(4+)-N caused by soil leaching. The loss proportion of NO(3-)-N in soil runoff decreased with the increasing nitrogen rate under the same tree-planting density, while that of NH(4+)-N increased. Leaching loss of NO(3-)-N had a similar trend with that of NH(4+)-N, i. e. , N3 > N2 > N1 > N0.

  8. Decision support system for determining Bantuan Siswa Miskin (BSM) receivers with profile matching method

    Science.gov (United States)

    Situmorang, B. H.; Pibriana, E.; Tosida, E. T.

    2018-03-01

    Bantuan Siswa Miskin (BSM) is a National Programs aimed at eliminating the barriers of poor students participating to school by helping poor students gain access to appropriate education services, prevent dropping out of school, attract poor students back to school, assis students in providing for learning activities, support the Nine Years Basic Education (and even up to senior high school) program, as well as helping to smooth the school programs [1]. Decision Support System is made by applying Profile Matching method to assist teachers or school operators in SMP PGRI Ciasmara in selecting prospective recipients of BSM program and providing recommendations in decision making. Profile Matching is used to compare the actual data value of a profile to be assessed by the expected profile value, so that it can be known the difference of competence (also called GAP). If the resulting value of GAP is smaller then the weight of value will be greater, which means it has a greater chance to be recommended as a potential recipient of the BSM program. Decision Support System for determining BSM receivers is only choosing the right alternatives to receive BSM according to the BSM quota given to SMP PGRI Ciasmara. The right alternatives to receive this BSM is the highest ranking alternatives.

  9. Design and verification of the miniature optical system for small object surface profile fast scanning

    Science.gov (United States)

    Chi, Sheng; Lee, Shu-Sheng; Huang, Jen, Jen-Yu; Lai, Ti-Yu; Jan, Chia-Ming; Hu, Po-Chi

    2016-04-01

    As the progress of optical technologies, different commercial 3D surface contour scanners are on the market nowadays. Most of them are used for reconstructing the surface profile of mold or mechanical objects which are larger than 50 mm×50 mm× 50 mm, and the scanning system size is about 300 mm×300 mm×100 mm. There are seldom optical systems commercialized for surface profile fast scanning for small object size less than 10 mm×10 mm×10 mm. Therefore, a miniature optical system has been designed and developed in this research work for this purpose. Since the most used scanning method of such system is line scan technology, we have developed pseudo-phase shifting digital projection technology by adopting projecting fringes and phase reconstruction method. A projector was used to project a digital fringe patterns on the object, and the fringes intensity images of the reference plane and of the sample object were recorded by a CMOS camera. The phase difference between the plane and object can be calculated from the fringes images, and the surface profile of the object was reconstructed by using the phase differences. The traditional phase shifting method was accomplished by using PZT actuator or precisely controlled motor to adjust the light source or grating and this is one of the limitations for high speed scanning. Compared with the traditional optical setup, we utilized a micro projector to project the digital fringe patterns on the sample. This diminished the phase shifting processing time and the controlled phase differences between the shifted phases become more precise. Besides, the optical path design based on a portable device scanning system was used to minimize the size and reduce the number of the system components. A screwdriver section about 7mm×5mm×5mm has been scanned and its surface profile was successfully restored. The experimental results showed that the measurement area of our system can be smaller than 10mm×10mm, the precision reached to

  10. Profile and Role of Woman Involvement in Dry System Pig Farming

    Directory of Open Access Journals (Sweden)

    Hartoko Hartoko

    2004-01-01

    Full Text Available This research was purposed to study the profile and role of woman involvement in dry system pig farming (pig housing with mattress from grass, pig manure, vegetable waste and kitchen waste.  The research was carried out from August to November 2003.  Pig housing areas were located on eight villages of Kertek District in Wonosobo Regency (Central Java.  The method applied was survey with intensive observation.  Sample were randomly selected, involved 180 respondents (15 percent of total pig farmers, while the locations of the sample were selected based on purposive sampling method.  The result showed that respondents were in productive age, with low formal education level. Most of all are Moslems (98% and they have small family size.  The level of woman involvement in pig farming was high, approximately 85 percent.  They have other income source and they involve in pig farming to help their husbands in generating income.  Experience in the dry system pig farming was quite long (more than 10 years and skill come from imitating their neighbours otherwise of autodidact. (Animal Production 6(1: 23-29 (2004   Key Words: Pig, Dry System, Woman Profile and Role

  11. Damage profiles and ion distribution in Pt-irradiated SiC

    Energy Technology Data Exchange (ETDEWEB)

    Xue, H.Z. [Department of Materials Science and Engineering, University of Tennessee, Knoxville, TN 37996 (United States); Zhang, Y., E-mail: Zhangy1@ornl.gov [Department of Materials Science and Engineering, University of Tennessee, Knoxville, TN 37996 (United States); Materials Science and Technology Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 (United States); Zhu, Z. [Pacific Northwest National Laboratory, P.O. Box 999, Richland, WA 99352 (United States); Zhang, W.M. [Department of Radiation Therapy, Peking University First Hospital, Beijing 100034 (China); Bae, I.-T. [Small Scale Systems Integration and Packaging Center, State University of New York at Binghamton, P.O. Box 6000, Binghamton, NY 13902 (United States); Weber, W.J. [Department of Materials Science and Engineering, University of Tennessee, Knoxville, TN 37996 (United States); Materials Science and Technology Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 (United States)

    2012-09-01

    Single crystalline 6H-SiC samples were irradiated at 150 K with 2 MeV Pt ions. The local volume swelling was determined by electron energy loss spectroscopy (EELS), and a nearly sigmoidal dependence on irradiation dose is observed. The disorder profiles and ion distribution were determined by Rutherford backscattering spectrometry (RBS), transmission electron microscopy, and secondary ion mass spectrometry. Since the volume swelling reaches 12% over the damage region at high ion fluence, the effect of lattice expansion is considered and corrected for in the analysis of RBS spectra to obtain depth profiles. Projectile and damage profiles are estimated by SRIM (Stopping and Range of Ions in Matter). When compared with the measured profiles, the SRIM code predictions of ion distribution and the damage profiles are underestimated due to significant overestimation of the electronic stopping power for the slow heavy Pt ions. By utilizing the reciprocity method, which is based on the invariance of the inelastic energy loss in ion-solid collisions against interchange of projectile and target atom, a much lower electronic stopping power is deduced. A simple approach, based on reducing the density of SiC target in SRIM simulation, is proposed to compensate the overestimated SRIM electronic stopping power values, which results in improved agreement between predicted and measured damage profiles and ion ranges.

  12. Contrasting vulnerability of drained tropical and high-latitude peatlands to fluvial loss of stored carbon

    Science.gov (United States)

    Evans, Chris D.; Page, Susan E.; Jones, Tim; Moore, Sam; Gauci, Vincent; Laiho, Raija; Hruška, Jakub; Allott, Tim E. H.; Billett, Michael F.; Tipping, Ed; Freeman, Chris; Garnett, Mark H.

    2014-11-01

    Carbon sequestration and storage in peatlands rely on consistently high water tables. Anthropogenic pressures including drainage, burning, land conversion for agriculture, timber, and biofuel production, cause loss of pressures including drainage, burning, land conversion for agriculture, timber, and biofuel production, cause loss of peat-forming vegetation and exposure of previously anaerobic peat to aerobic decomposition. This can shift peatlands from net CO2 sinks to large CO2 sources, releasing carbon held for millennia. Peatlands also export significant quantities of carbon via fluvial pathways, mainly as dissolved organic carbon (DOC). We analyzed radiocarbon (14C) levels of DOC in drainage water from multiple peatlands in Europe and Southeast Asia, to infer differences in the age of carbon lost from intact and drained systems. In most cases, drainage led to increased release of older carbon from the peat profile but with marked differences related to peat type. Very low DOC-14C levels in runoff from drained tropical peatlands indicate loss of very old (centuries to millennia) stored peat carbon. High-latitude peatlands appear more resilient to drainage; 14C measurements from UK blanket bogs suggest that exported DOC remains young (use changes in the tropics. Data from the UK Peak District, an area where air pollution and intensive land management have triggered Sphagnum loss and peat erosion, suggest that additional anthropogenic pressures may trigger fluvial loss of much older (>500 year) carbon in high-latitude systems. Rewetting at least partially offsets drainage effects on DOC age.

  13. Comparisons of Social Competence in Young Children with and without Hearing Loss: A Dynamic Systems Framework

    Science.gov (United States)

    Hoffman, Michael F.; Quittner, Alexandra L.; Cejas, Ivette

    2015-01-01

    This study compared levels of social competence and language development in 74 young children with hearing loss and 38 hearing peers aged 2.5-5.3 years. This study was the first to examine the relationship between oral language and social competence using a dynamic systems framework in children with and without hearing loss. We hypothesized that,…

  14. Closeout of IE Bulletin 80-15: Possible loss of Emergency Notification System (ENS) with loss of offsite power

    International Nuclear Information System (INIS)

    Foley, W.J.; Dean, R.S.; Hennick, A.

    1990-12-01

    Documentation is provided in this report for the closeout of IE Bulletin 80-15 for nuclear power reactors. This bulletin pertained to a possible loss of the Emergency Notification System (ENS) upon loss of offsite power. Closeout is based on the implementation and verification of six (6) required actions by licensees of nuclear power reactors in operation or near to receiving an operating license when the bulletin was issued on June 18, 1980. Evaluation of utility responses and NRC/Region inspection reports indicates that the bulletin is closed for all of the 69 nuclear power reactors to which it was issued for action and which were not shut down indefinitely or permanently at the time of issuance of this report. Background information is supplied in the Introduction and Appendix A. Nuclear fuel facilities as well as nuclear power facilities were identified in the enclosures to the bulletin. However, per an NRC memorandum, the closeout of the bulletin for nuclear fuel facilities is not within the scope of this report

  15. System transient response to loss of off-site power

    International Nuclear Information System (INIS)

    Sozer, A.

    1990-01-01

    A simultaneous trip of the reactor, main circulation pumps, secondary coolant pumps, and pressurizer pump due to loss of off-site power at the High Flux Isotope Reactor (HFIR) located at the Oak Ridge National Laboratory (ORNL) has been analyzed to estimate available safety margin. A computer model based on the Modular Modeling System code has been used to calculate the transient response of the system. The reactor depressurizes from 482.7 psia down to about 23 psia in about 50 seconds and remains stable thereafter. Available safety margin has been estimated in terms of the incipient boiling heat flux ratio. It is a conservative estimate due to assumed less than available primary and secondary flows and higher than normal depressurization rate. The ratio indicates no incipient boiling conditions at the hot spot. No potential damage to the fuel is likely to occur during this transient. 2 refs., 6 figs

  16. The applicability of a weight loss grading system in cancer cachexia: a longitudinal analysis.

    Science.gov (United States)

    Vagnildhaug, Ola Magne; Blum, David; Wilcock, Andrew; Fayers, Peter; Strasser, Florian; Baracos, Vickie E; Hjermstad, Marianne J; Kaasa, Stein; Laird, Barry; Solheim, Tora S

    2017-10-01

    A body mass index (BMI) adjusted weight loss grading system (WLGS) is related to survival in patients with cancer. The aim of this study was to examine the applicability of the WLGS by confirming its prognostic validity, evaluating its relationship to cachexia domains, and exploring its ability to predict cachexia progression. An international, prospective observational study of patients with incurable cancer was conducted. For each patient, weight loss grade was scored 0-4. Weight loss grade 0 represents a high BMI with limited weight loss, progressing through to weight loss grade 4 representing low BMI and a high degree of weight loss. Survival analyses were used to confirm prognostic validity. Analyses of variance were used to evaluate the relationship between the WLGS and cachexia domains [anorexia, dietary intake, Karnofsky performance status (KPS), and physical and emotional functioning]. Cox regression was used to evaluate if the addition of cachexia domains to the WLGS improved prognostic accuracy. Predictive ability of cachexia progression was assessed by estimating proportion of patients progressing to a more advanced weight loss grade. One thousand four hundred six patients were analysed (median age 66 years; 50% female, 63% KPS ≤ 70). The overall effect of the WLGS on survival was significant as expressed by change in -2 log likelihood (P cachexia domains significantly deteriorated with increasing weight loss grade, and deterioration was greatest for dietary intake, with a difference corresponding to 0.87 standard deviations between weight loss grades 0 and 4. The addition of KPS, anorexia, and physical and emotional functioning improved the prognostic accuracy of the WLGS. Likelihood of cachexia progression was greater in patients with weight loss grade 2 (39%) than that with weight loss grade 0 (19%) or 1 (22%). The WLGS is related to survival, cachexia domains, and the likelihood of progression. Adding certain cachexia domains to the WLGS

  17. Non-destructive profile measurement of intensive heavy ion beams; Zerstoerungsfreie Profilmessung intensiver Schwerionenstrahlen

    Energy Technology Data Exchange (ETDEWEB)

    Becker, Frank

    2010-02-08

    linear dependence on the gas-pressure for constant profile width and as well as the light yield being proportional to the differential energy loss. For nitrogen, spectral investigation shows a four times higher light yield compared to rare gas species, normalized with respect to the differential energy loss. Helium is the only rare gas that shows broadened beam profiles. All other rare gases and nitrogen show reasonable beam profiles that correspond well with each other. Furthermore the dose-distribution in a cave for beam energies ≥ 100 AMeV was measured and simulated in order to develop a shielding concept that protects the camera system against radiation damage. According to simulations the neutron dose decreases by 94 % in the center of a 1 m{sup 3} concrete cube. Possible profile distortions due to effects like momentum transfer, gas dynamics and the electrical field of the ion beam are discussed. Technical improvements are presented.

  18. A new approach for optimum DG placement and sizing based on voltage stability maximization and minimization of power losses

    International Nuclear Information System (INIS)

    Aman, M.M.; Jasmon, G.B.; Bakar, A.H.A.; Mokhlis, H.

    2013-01-01

    Highlights: • A new algorithm is proposed for optimum DG placement and sizing.• I 2 R losses minimization and voltage stability maximization is considered in fitness function.• Bus voltage stability and line stability is considered in voltage stability maximization.• Multi-objective PSO is used to solve the problem.• Proposed method is compared with analytical and grid search algorithm. - Abstract: Distributed Generation (DG) placement on the basis of minimization of losses and maximization of system voltage stability are two different approaches, discussed in research. In the new proposed algorithm, a multi-objective approach is used to combine the both approaches together. Minimization of power losses and maximization of voltage stability due to finding weakest voltage bus as well as due to weakest link in the system are considered in the fitness function. Particle Swarm Optimization (PSO) algorithm is used in this paper to solve the multi-objective problem. This paper will also compare the propose method with existing DG placement methods. From results, the proposed method is found more advantageous than the previous work in terms of voltage profile improvement, maximization of system loadability, reduction in power system losses and maximization of bus and line voltage stability. The results are validated on 12-bus, 30-bus, 33-bus and 69-bus radial distribution networks and also discussed in detailed

  19. The impact of loss sensitivity on a mobile phone supply chain system stability based on the chaos theory

    Science.gov (United States)

    Ma, Junhai; Xie, Lei

    2018-02-01

    This paper, based on the China's communications and the current situation of the mobile phone industry, focuses on the stability of a supply chain system that consists of one supplier and one bounded rational retailer. We explore the influence of the decision makers' loss sensitivity and decision adjustment speed on the stability of the supply chain. It is found that when the retailer is not sensitive to the loss or adjusts decisions cautiously, the system can be stable. The single-retailer model is extended to a multi-retailer one to study the influence of competition on the system stability. The results show that the market share of each retailer does not affect the system stability when it is fixed. The decision of each retailer does not affect that of any other retailer and the system stability. We present two decision adjustment rules (;bounded rationality expectation (BRE); and "adaptive exponential smoothing (AES)") and compare their performances on the system stability, and find that the AES rule does not affect the system stability, while the BRE rule will make the system stability be sensitive to the retailers' loss sensitivity and the decision adjustment speed. We also reveal the unstable system's negative impact on the retailers' decisions and profits, to emphasize the importance to maintain the system stability.

  20. Profiles of Automotive Suppliers Industries--Engineered Mechanical Components and Systems : Volume II, Appendices.

    Science.gov (United States)

    1981-09-01

    The profile describes and analyzes that segment of the automotive supplier industry which provides engineered mechanical components/assemblies/systems to the prime auto manufacturers. It presents an overview of the role and structure of this industry...

  1. Profiles of Automotive Suppliers Industries--Engineered Mechanical Components and Systems : Volume I, Text.

    Science.gov (United States)

    1981-09-01

    This profile describes and analyzes that segment of the automotive supplier industry which provides engineered mechanical components/assemblies/systems to the prime auto manufacturers. It presents an overview of the role and structure of this industr...

  2. Study of off-momentum losses at the start of the ramp in the Large Hadron Collider

    CERN Document Server

    Wretborn, Sven Joel; Garcia Morales, Hector; Sjobaek, Kyrre Ness; CERN. Geneva. ATS Department

    2017-01-01

    At the start of the energy ramp at the LHC, any uncaptured beam is quickly lost on the momentum collimators. This causes significant instantaneous losses, and it is therefore important to understand these losses in detail in case they would become critical at the LHC itself or in future machines. This note aims at first analyzing data of these losses from the 2016 LHC run to quantify their features. Then, simulation methods are developed. First a simple but fast one-turn map model is used to study the phase space motion and the expected time profile of losses, after which SixTrack is used to provide a more complete simulation environment including all machine elements together with scattering in the collimators. A combined simulation, where first the Toy model is used to track particles for the first 11 s of the ramp, before they are handed over to SixTrack, is shown to be reasonably fast and to produce loss maps that qualitatively agree with the measurements. The time profile of the measured losses is used t...

  3. Research and application of online measurement system of tire tread profile in automobile tire production

    Science.gov (United States)

    Wang, Pengyao; Chen, Xiangguang; Yang, Kai; Liu, Xuejiao

    2017-01-01

    To improve the measuring efficiency of width and thickness of tire tread in the process of automobile tire production, the actual condition for the tire production process is analyzed, and a fast online measurement system based on moving tire tread of tire specifications is established in this paper. The coordinate data of tire tread profile is acquired by 3D laser sensor, and we use C# language for programming which is an object-oriented programming language to complete the development of client program. The system with laser sensor can provide real-time display of tire tread profile and the data to require in the process of tire production. Experimental results demonstrate that the measuring precision of the system is <= 1mm, it can meet the measurement requirements of the production process, and the system has the characteristics of convenient installation and testing, system stable operation.

  4. TREES OF DAMAGES AS A MODEL OF RISKS ASSESSMENT FOR AVAILABILITY LOSSES AFTER CHANGES IN FINANCIAL INFORMATION SYSTEMS

    Directory of Open Access Journals (Sweden)

    S. A. Arustamov

    2013-03-01

    Full Text Available The article deals with the methodology for risks assessment of availability losses in financial information systems after changes made in them by using trees of damages. A description of damages tree generation for each identified possible event is presented that potentially can lead to the system availability loss. An example is given, illustrating the methodology application that gives the possibility to choose the optimal software testing strategy.

  5. Modal loss mechanism of micro-structured VCSELs studied using full vector FDTD method.

    Science.gov (United States)

    Jo, Du-Ho; Vu, Ngoc Hai; Kim, Jin-Tae; Hwang, In-Kag

    2011-09-12

    Modal properties of vertical cavity surface-emitting lasers (VCSELs) with holey structures are studied using a finite difference time domain (FDTD) method. We investigate loss behavior with respect to the variation of structural parameters, and explain the loss mechanism of VCSELs. We also propose an effective method to estimate the modal loss based on mode profiles obtained using FDTD simulation. Our results could provide an important guideline for optimization of the microstructures of high-power single-mode VCSELs.

  6. MEMBRANE ACTION IN PROFILED STEEL SHEETING DRY BOARD (PSSDB FLOOR SLAB SYSTEM

    Directory of Open Access Journals (Sweden)

    MAHMOOD SERAJI

    2013-02-01

    Full Text Available Profiled steel sheeting dry board (PSSDB system is a lightweight composite structural system that made of the profiled steel sheeting (PSS connected to the dry board (DB by self-drilling and self-tapping screws. The objective of this paper is to study the effect of membrane action in improving the flexural capacities of the PSSDB system. According to the literatures, common failure of the PSSDB floor is due to local buckling in the top flanges of steel sheeting at the centre of a simply supported slab. Restraining the horizontal movement at supports may develop the membrane action (MA in the slab that can remarkably enhance the flexural rigidities of the floor. Experimental tests were conducted along with developing nonlinear finite element model to explore the effect of MA in the PSSDB floor. Experimental results of the PSSDB panel with simply end support were exploited to verify the nonlinear finite element results. The developed finite element model was then modified by restraining the horizontal movement of the slab at the supports. The obtained results disclosed that the developed compressive membrane action enhanced the stiffness of the slab at serviceability load by about 240%.

  7. Control of Sewer systems and Wastewater treatment plants using pollutant concentration profiles

    DEFF Research Database (Denmark)

    Bechmann, Henrik; Nielsen, Marinus K.; Madsen, Henrik

    1998-01-01

    On-line measurements of pollutants in the wastewater combined with grey-box modelling are used to estimate the amount of deposits in the sewer system. The pollutant mass flow at the wastewater treatment plant is found to consist of a diurnal profile minus the deposited amount of pollutants...

  8. Fast ion loss and radial electric field in high-aspect-ratio stellarator

    International Nuclear Information System (INIS)

    Itoh, Kimitaka; Sanuki, Heiji; Itoh, Sanae

    1992-01-01

    Theoretical model is developed to determine the radial electric field and the fast ion loss simultaneously in stellarators, and is applied to the Wendelstein VII-A stellarator. The predicted value of the radial electric field is more close to experiments than the purely neoclassical calculation. The loss rate, which is determined simultaneously, is in the range of experimental observations. The partition of the injection energy by the bulk heating, direct orbit loss and shine through is estimated by using the selfconsistent electric field profile. The orbit loss becomes noticeable as the injection energy increases. The influence of the neutral particles is also studied. Neutral particles enhance the negative radial electric field, and reduce the direct orbit loss by the expense of the charge exchange loss. The impact of the increased radial electric field on the neoclassical ion thermal energy loss is compared to the direct loss of fast ions. The reduction of the neoclassical loss is much smaller than the orbit loss. (author)

  9. Fast ion loss and radial electric field in Wendelstein VII-Λ stellarator

    International Nuclear Information System (INIS)

    Itoh, K.; Sanuki, H.; Itoh, S.

    1991-10-01

    Theoretical model is developed to determine the radial electric field and the fast ion loss simultaneously in stellarators, and is applied to the Wendelstein VII-A stellarator. The predicted value of the radial electric field is more closer to experiments than the purely neoclassical calculation. The loss rate, which is determined simultaneously, is in the range of experimental observations. The partition of the injection energy by the bulk heating, direct orbit loss and shine through is estimated by using the self consistent electric field profile. The orbit loss become noticeable as the injection energy increases. The influence of the neutral particles is also studied. Neutral particles enhances the negative radial electric field, and reduces the direct orbit loss by the expense of the charge exchange loss. The impact of the increased radial electric field on the neoclassical ion thermal energy loss is compared to the direct loss of fast ions. The reduction of the neoclassical loss is much smaller than the orbit loss. (author)

  10. Measuring and heat losses for district heating systems in detached house areas; Maet- och vaermefoerluster foer fjaerrvaermesystem i smaahusomraaden

    Energy Technology Data Exchange (ETDEWEB)

    Cederborg, Frederick; Nordgren, Ola [FVB Sverige ab, Vaesteraas (Sweden)

    2005-07-01

    Within 'low heat load' areas e.g. residential areas, with low energy consumption per individual customer, the resulting relationship between the heat loss and the energy sales is big. For these customers with low energy consumption, in particular during the summer season, concerns have been raised regarding the ability of the heat volume meters to register the true energy consumption. In order to determine the magnitude of the losses, the Swedish District Heating Association, has initiated a measuring project where measurements have been made in two separate residential areas with different system configurations and different temperature control programs. The measurements were performed from May 15, 2003 to September 23, 2004. The main objective for the project was to gather data and to analyse the magnitude of the total losses in the building systems. The relation between the heat losses and the measuring losses was also studied briefly. Two types of systems have been studied, on one hand a conventional district heating area with primary connected houses and on the other hand an area with secondary connected houses with PEX-pipes in Enkoeping. The heat and measuring losses at the area Munksundet in Enkoeping is 17 % at a 'load density' of 0,84. This value is somewhat lower than the accounted annual relative loss of 22-23 % stated in the report 'FVF 1997:11 Fjaerrvaerme till smaahus'. The results show that a secondary connected low temperature system with PEX-pipes is an interesting connection alternative for small houses. Also at the residential area Rotskaer in Skutskaer, the heat and measuring losses are lower than the accounted annual relative loss, about 24 % at a 'load density' of 0,49,which is to be compared with about 33 % annual relative loss according to the report 'FVF 1997:11'. Within this assignment there are difficulties to divide the measuring losses in short circuit flows and errors in the heat

  11. Energy-loss return gate via liquid dielectric polarization.

    Science.gov (United States)

    Kim, Taehun; Yong, Hyungseok; Kim, Banseok; Kim, Dongseob; Choi, Dukhyun; Park, Yong Tae; Lee, Sangmin

    2018-04-12

    There has been much research on renewable energy-harvesting techniques. However, owing to increasing energy demands, significant energy-related issues remain to be solved. Efforts aimed at reducing the amount of energy loss in electric/electronic systems are essential for reducing energy consumption and protecting the environment. Here, we design an energy-loss return gate system that reduces energy loss from electric/electronic systems by utilizing the polarization of liquid dielectrics. The use of a liquid dielectric material in the energy-loss return gate generates electrostatic potential energy while reducing the dielectric loss of the electric/electronic system. Hence, an energy-loss return gate can make breakthrough impacts possible by amplifying energy-harvesting efficiency, lowering the power consumption of electronics, and storing the returned energy. Our study indicates the potential for enhancing energy-harvesting technologies for electric/electronics systems, while increasing the widespread development of these systems.

  12. Microgrids: Energy management by loss minimization technique

    Energy Technology Data Exchange (ETDEWEB)

    Basu, A.K. [Electrical Engineering Dept., Jadavpur University & 20/2, Khanpur Road, Kolkata 700047 (India); Chowdhury, S.; Chowdhury, S.P. [Electrical Engineering Department, University of Cape Town & Private Bag X3, Menzies Building, Room-517, Rondebosch, Cape Town 7701 (India)

    2011-07-01

    Energy management is a techno-economic issue, which dictates, in the context of microgrids, how optimal investment in technology front could bring optimal power quality and reliability (PQR) of supply to the consumers. Investment in distributed energy resources (DERs), with their connection to the utility grid at optimal locations and with optimal sizes, saves energy in the form of line loss reduction. Line loss reduction is the indirect benefit to the microgrid owner who may recover it as an incentive from utility. The present paper focuses on planning of optimal siting and sizing of DERs based on minimization of line loss. Optimal siting is done, here, on the loss sensitivity index (LSI) method and optimal sizing by differential evolution (DE) algorithms, which is, again, compared with particle swarm optimization (PSO) technique. Studies are conducted on 6-bus and 14-bus radial networks under islanded mode of operation with electric demand profile. Islanding helps planning of DER capacity of microgrid, which is self-sufficient to cater its own consumers without utility's support.

  13. Micronutrient Gaps in Three Commercial Weight-Loss Diet Plans.

    Science.gov (United States)

    G Engel, Matthew; J Kern, Hua; Brenna, J Thomas; H Mitmesser, Susan

    2018-01-20

    Weight-loss diets restrict intakes of energy and macronutrients but overlook micronutrient profiles. Commercial diet plans may provide insufficient micronutrients. We analyzed nutrient profiles of three plans and compared their micronutrient sufficiency to Dietary Reference Intakes (DRIs) for male U.S. adults. Hypocaloric vegan (Eat to Live-Vegan, Aggressive Weight Loss; ETL-VAWL), high-animal-protein low-carbohydrate (Fast Metabolism Diet; FMD) and weight maintenance (Eat, Drink and Be Healthy; EDH) diets were evaluated. Seven single-day menus were sampled per diet ( n = 21 menus, 7 menus/diet) and analyzed for 20 micronutrients with the online nutrient tracker CRON-O-Meter. Without adjustment for energy intake, the ETL-VAWL diet failed to provide 90% of recommended amounts for B 12 , B₃, D, E, calcium, selenium and zinc. The FMD diet was low (90% DRIs for all but vitamin D, calcium and potassium. Several micronutrients remained inadequate after adjustment to 2000 kcal/day: vitamin B 12 in ETL-VAWL, calcium in FMD and EDH and vitamin D in all diets. Consistent with previous work, micronutrient deficits are prevalent in weight-loss diet plans. Special attention to micronutrient rich foods is required to reduce risk of micronutrient deficiency in design of commercial diets.

  14. Micronutrient Gaps in Three Commercial Weight-Loss Diet Plans

    Science.gov (United States)

    J. Kern, Hua; Brenna, J. Thomas; H. Mitmesser, Susan

    2018-01-01

    Weight-loss diets restrict intakes of energy and macronutrients but overlook micronutrient profiles. Commercial diet plans may provide insufficient micronutrients. We analyzed nutrient profiles of three plans and compared their micronutrient sufficiency to Dietary Reference Intakes (DRIs) for male U.S. adults. Hypocaloric vegan (Eat to Live-Vegan, Aggressive Weight Loss; ETL-VAWL), high-animal-protein low-carbohydrate (Fast Metabolism Diet; FMD) and weight maintenance (Eat, Drink and Be Healthy; EDH) diets were evaluated. Seven single-day menus were sampled per diet (n = 21 menus, 7 menus/diet) and analyzed for 20 micronutrients with the online nutrient tracker CRON-O-Meter. Without adjustment for energy intake, the ETL-VAWL diet failed to provide 90% of recommended amounts for B12, B3, D, E, calcium, selenium and zinc. The FMD diet was low (diet met >90% DRIs for all but vitamin D, calcium and potassium. Several micronutrients remained inadequate after adjustment to 2000 kcal/day: vitamin B12 in ETL-VAWL, calcium in FMD and EDH and vitamin D in all diets. Consistent with previous work, micronutrient deficits are prevalent in weight-loss diet plans. Special attention to micronutrient rich foods is required to reduce risk of micronutrient deficiency in design of commercial diets. PMID:29361684

  15. Device- and service profiles for integrated or systems based on open standards

    Directory of Open Access Journals (Sweden)

    Mildner Alexander

    2015-09-01

    Full Text Available Integrated OR systems nowadays are closed and proprietary, so that the interconnection of components from third-party vendors is only possible with high time and cost effort. An integrated operating theatre with open interfaces, giving clinical operators the opportunity to choose individual medical devices from different manufacturers, is currently being developed in the framework of the BMBF (Federal Ministry of Education and Research funded project OR.NET [1]. Actual standards and concepts regarding technical feasibility and accreditation process do not cope with the requirements for modular integration based on an open standard. Therefore, strategies as well as service and device profiles to enable a procedure for risk management and certifiability are in the focus of the project work. Amongst others, a concept for User Interface Profiles (UI-Profiles has been conceived in order to describe medical device functions and the entire user interface regarding Human-Machine-Interaction (HMI characteristics with the aim to identify human-induced risks of central user interfaces. The use of standardized device and service profiles shall allow the manufacturers to integrate their medical devices in the OR.NET network, without disclosing the medical devices’ risk analysis and related confidential knowledge or proprietary information.

  16. Entropy of gravitating systems: scaling laws versus radial profiles

    International Nuclear Information System (INIS)

    Pesci, Alessandro

    2007-01-01

    Through the consideration of spherically symmetric gravitating systems consisting of perfect fluids with linear equation of state constrained to be in a finite volume, an account is given of the properties of entropy at conditions in which it is no longer an extensive quantity (it does not scale with the system's size). To accomplish this, the methods introduced by Oppenheim (2003 Phys. Rev.E 68 016108) to characterize non-extensivity are used, suitably generalized to the case of gravitating systems subject to an external pressure. In particular when, far from the system's Schwarzschild limit, both area scaling for conventional entropy and inverse radius law for the temperature set in (i.e. the same properties of the corresponding black hole thermodynamical quantities), the entropy profile is found to behave like 1/r, with r the area radius inside the system. In such circumstances entropy heavily resides in internal layers, in opposition to what happens when area scaling is gained while approaching the Schwarzschild mass, in which case conventional entropy lies at the surface of the system. The information content of these systems, even if it globally scales like the area, is then stored in the whole volume, instead of packed on the boundary

  17. Development of a Climatology of Vertically Complete Wind Profiles from Doppler Radar Wind Profiler Systems

    Science.gov (United States)

    Barbre, Robert E., Jr.

    2015-01-01

    This paper describes in detail the QC and splicing methodology for KSC's 50- and 915-MHz DRWP measurements that generates an extensive archive of vertically complete profiles from 0.20-18.45 km. The concurrent POR from each archive extends from April 2000 to December 2009. MSFC NE applies separate but similar QC processes to each of the 50- and 915-MHz DRWP archives. DRWP literature and data examination provide the basis for developing and applying the automated and manual QC processes on both archives. Depending on the month, the QC'ed 50- and 915-MHz DRWP archives retain 52-65% and 16-30% of the possible data, respectively. The 50- and 915-MHz DRWP QC archives retain 84-91% and 85-95%, respectively, of all the available data provided that data exist in the non- QC'ed archives. Next, MSFC NE applies an algorithm to splice concurrent measurements from both DRWP sources. Last, MSFC NE generates a composite profile from the (up to) five available spliced profiles to effectively characterize boundary layer winds and to utilize all possible 915-MHz DRWP measurements at each timestamp. During a given month, roughly 23,000-32,000 complete profiles exist from 0.25-18.45 km from the composite profiles' archive, and approximately 5,000- 27,000 complete profiles exist from an archive utilizing an individual 915-MHz DRWP. One can extract a variety of profile combinations (pairs, triplets, etc.) from this sample for a given application. The sample of vertically complete DRWP wind measurements not only gives launch vehicle customers greater confidence in loads and trajectory assessments versus using balloon output, but also provides flexibility to simulate different DOL situations across applicable altitudes. In addition to increasing sample size and providing more flexibility for DOL simulations in the vehicle design phase, the spliced DRWP database provides any upcoming launch vehicle program with the capability to utilize DRWP profiles on DOL to compute vehicle steering

  18. A new method for depth profiling reconstruction in confocal microscopy

    Science.gov (United States)

    Esposito, Rosario; Scherillo, Giuseppe; Mensitieri, Giuseppe

    2018-05-01

    Confocal microscopy is commonly used to reconstruct depth profiles of chemical species in multicomponent systems and to image nuclear and cellular details in human tissues via image intensity measurements of optical sections. However, the performance of this technique is reduced by inherent effects related to wave diffraction phenomena, refractive index mismatch and finite beam spot size. All these effects distort the optical wave and cause an image to be captured of a small volume around the desired illuminated focal point within the specimen rather than an image of the focal point itself. The size of this small volume increases with depth, thus causing a further loss of resolution and distortion of the profile. Recently, we proposed a theoretical model that accounts for the above wave distortion and allows for a correct reconstruction of the depth profiles for homogeneous samples. In this paper, this theoretical approach has been adapted for describing the profiles measured from non-homogeneous distributions of emitters inside the investigated samples. The intensity image is built by summing the intensities collected from each of the emitters planes belonging to the illuminated volume, weighed by the emitters concentration. The true distribution of the emitters concentration is recovered by a new approach that implements this theoretical model in a numerical algorithm based on the Maximum Entropy Method. Comparisons with experimental data and numerical simulations show that this new approach is able to recover the real unknown concentration distribution from experimental profiles with an accuracy better than 3%.

  19. Identification of LHC beam loss mechanism : a deterministic treatment of loss patterns

    CERN Document Server

    Marsili, Aurélien

    CERN's Large Hadron Collider (LHC) is the largest machine ever built, with a total circumference of 26.7 km; and it is the most powerful accelerator ever, both in beam energy and beam intensity. The main magnets are superconducting, keeping the particles into two counter circulating beams, which collide in four interaction points. CERN and the LHC will be described in chap. 1. The superconducting magnets of the LHC have to be protected against particle losses. Depending on the number of lost particles, the coils of the magnets will become normal conducting and/or will be damaged. To avoid these events a beam loss monitoring (BLM) system was installed to measure the particle loss rates. If the predefined safe thresholds of loss rates are exceeded, the beams are directed out of the accelerator ring towards the beam dump. The detectors of the BLM system are mainly ionization chambers located outside of the cryostats. In total, about 3500 ionisation chambers are installed. Further challenges include the high dyna...

  20. Data Fusion to Develop a Driver Drowsiness Detection System with Robustness to Signal Loss

    Directory of Open Access Journals (Sweden)

    Sajjad Samiee

    2014-09-01

    Full Text Available This study proposes a drowsiness detection approach based on the combination of several different detection methods, with robustness to the input signal loss. Hence, if one of the methods fails for any reason, the whole system continues to work properly. To choose correct combination of the available methods and to utilize the benefits of methods of different categories, an image processing-based technique as well as a method based on driver-vehicle interaction is used. In order to avoid driving distraction, any use of an intrusive method is prevented. A driving simulator is used to gather real data and then artificial neural networks are used in the structure of the designed system. Several tests were conducted on twelve volunteers while their sleeping situations during one day prior to the tests, were fully under control. Although the impact of the proposed system on the improvement of the detection accuracy is not remarkable, the results indicate the main advantages of the system are the reliability of the detections and robustness to the loss of the input signals. The high reliability of the drowsiness detection systems plays an important role to reduce drowsiness related road accidents and their associated costs.

  1. Depth-selective X-ray absorption spectroscopy by detection of energy-loss Auger electrons

    Energy Technology Data Exchange (ETDEWEB)

    Isomura, Noritake, E-mail: isomura@mosk.tytlabs.co.jp [Toyota Central R& D Labs., Inc., 41-1 Yokomichi, Nagakute, Aichi 480-1192 (Japan); Soejima, Narumasa; Iwasaki, Shiro [Toyota Central R& D Labs., Inc., 41-1 Yokomichi, Nagakute, Aichi 480-1192 (Japan); Nomoto, Toyokazu; Murai, Takaaki [Aichi Synchrotron Radiation Center (AichiSR), 250-3 Minamiyamaguchi-cho, Seto, Aichi 489-0965 (Japan); Kimoto, Yasuji [Toyota Central R& D Labs., Inc., 41-1 Yokomichi, Nagakute, Aichi 480-1192 (Japan)

    2015-11-15

    Graphical abstract: - Highlights: • A unique XAS method is proposed for depth profiling of chemical states. • PEY mode detecting energy-loss electrons enables a variation in the probe depth. • Si K-edge XAS spectra of the Si{sub 3}N{sub 4}/SiO{sub 2}/Si multilayer films have been investigated. • Deeper information was obtained in the spectra measured at larger energy loss. • Probe depth could be changed by the selection of the energy of detected electrons. - Abstract: A unique X-ray absorption spectroscopy (XAS) method is proposed for depth profiling of chemical states in material surfaces. Partial electron yield mode detecting energy-loss Auger electrons, called the inelastic electron yield (IEY) mode, enables a variation in the probe depth. As an example, Si K-edge XAS spectra for a well-defined multilayer sample (Si{sub 3}N{sub 4}/SiO{sub 2}/Si) have been investigated using this method at various kinetic energies. We found that the peaks assigned to the layers from the top layer to the substrate appeared in the spectra in the order of increasing energy loss relative to the Auger electrons. Thus, the probe depth can be changed by the selection of the kinetic energy of the energy loss electrons in IEY-XAS.

  2. Depth-selective X-ray absorption spectroscopy by detection of energy-loss Auger electrons

    International Nuclear Information System (INIS)

    Isomura, Noritake; Soejima, Narumasa; Iwasaki, Shiro; Nomoto, Toyokazu; Murai, Takaaki; Kimoto, Yasuji

    2015-01-01

    Graphical abstract: - Highlights: • A unique XAS method is proposed for depth profiling of chemical states. • PEY mode detecting energy-loss electrons enables a variation in the probe depth. • Si K-edge XAS spectra of the Si_3N_4/SiO_2/Si multilayer films have been investigated. • Deeper information was obtained in the spectra measured at larger energy loss. • Probe depth could be changed by the selection of the energy of detected electrons. - Abstract: A unique X-ray absorption spectroscopy (XAS) method is proposed for depth profiling of chemical states in material surfaces. Partial electron yield mode detecting energy-loss Auger electrons, called the inelastic electron yield (IEY) mode, enables a variation in the probe depth. As an example, Si K-edge XAS spectra for a well-defined multilayer sample (Si_3N_4/SiO_2/Si) have been investigated using this method at various kinetic energies. We found that the peaks assigned to the layers from the top layer to the substrate appeared in the spectra in the order of increasing energy loss relative to the Auger electrons. Thus, the probe depth can be changed by the selection of the kinetic energy of the energy loss electrons in IEY-XAS.

  3. A new reconfiguration scheme for voltage stability enhancement of radial distribution systems

    International Nuclear Information System (INIS)

    Arun, M.; Aravindhababu, P.

    2009-01-01

    Network reconfiguration is an operation problem, which entails altering the topological structure of the distribution feeders by rearranging the status of switches in order to obtain an optimal configuration in order to minimise the system losses. This paper presents a new reconfiguration algorithm that enhances voltage stability and improves the voltage profile besides minimising losses without incurring any additional cost for installation of capacitors, tap changing transformers and related switching equipment in the distribution system. Test results on a 69 node distribution system reveal the superiority of this algorithm.

  4. Analysis on the Role of RSG-GAS Pool Cooling System during Partial Loss of Heat Sink Accident

    Science.gov (United States)

    Susyadi; Endiah, P. H.; Sukmanto, D.; Andi, S. E.; Syaiful, B.; Hendro, T.; Geni, R. S.

    2018-02-01

    RSG-GAS is a 30 MW reactor that is mostly used for radioisotope production and experimental activities. Recently, it is regularly operated at half of its capacity for efficiency reason. During an accident, especially loss of heat sink, the role of its pool cooling system is very important to dump decay heat. An analysis using single failure approach and partial modeling of RELAP5 performed by S. Dibyo, 2010 shows that there is no significant increase in the coolant temperature if this system is properly functioned. However lessons learned from the Fukushima accident revealed that an accident can happen due to multiple failures. Considering ageing of the reactor, in this research the role of pool cooling system is to be investigated for a partial loss of heat sink accident which is at the same time the protection system fails to scram the reactor when being operated at 15 MW. The purpose is to clarify the transient characteristics and the final state of the coolant temperature. The method used is by simulating the system in RELAP5 code. Calculation results shows the pool cooling systems reduce coolant temperature for about 1 K as compared without activating them. The result alsoreveals that when the reactor is being operated at half of its rated power, it is still in safe condition for a partial loss of heat sink accident without scram.

  5. Overview of recurrent chromosomal losses in retinoblastoma detected by low coverage next generation sequencing

    Science.gov (United States)

    García-Chequer, A.J.; Méndez-Tenorio, A.; Olguín-Ruiz, G.; Sánchez-Vallejo, C.; Isa, P.; Arias, C.F.; Torres, J.; Hernández-Angeles, A.; Ramírez-Ortiz, M.A.; Lara, C.; Cabrera-Muñoz, M.L.; Sadowinski-Pine, S.; Bravo-Ortiz, J.C.; Ramón-García, G.; Diegopérez-Ramírez, J.; Ramírez-Reyes, G.; Casarrubias-Islas, R.; Ramírez, J.; Orjuela, M.A.; Ponce-Castañeda, M.V.

    2016-01-01

    Genes are frequently lost or gained in malignant tumors and the analysis of these changes can be informative about the underlying tumor biology. Retinoblastoma is a pediatric intraocular malignancy, and since deletions in chromosome 13 have been described in this tumor, we performed genome wide sequencing with the Illumina platform to test whether recurrent losses could be detected in low coverage data from DNA pools of Rb cases. An in silico reference profile for each pool was created from the human genome sequence GRCh37p5; a chromosome integrity score and a graphics 40 Kb window analysis approach, allowed us to identify with high resolution previously reported non random recurrent losses in all chromosomes of these tumors. We also found a pattern of gains and losses associated to clear and dark cytogenetic bands respectively. We further analyze a pool of medulloblastoma and found a more stable genomic profile and previously reported losses in this tumor. This approach facilitates identification of recurrent deletions from many patients that may be biological relevant for tumor development. PMID:26883451

  6. Beam Loss Monitoring for LHC Machine Protection

    Science.gov (United States)

    Holzer, Eva Barbara; Dehning, Bernd; Effnger, Ewald; Emery, Jonathan; Grishin, Viatcheslav; Hajdu, Csaba; Jackson, Stephen; Kurfuerst, Christoph; Marsili, Aurelien; Misiowiec, Marek; Nagel, Markus; Busto, Eduardo Nebot Del; Nordt, Annika; Roderick, Chris; Sapinski, Mariusz; Zamantzas, Christos

    The energy stored in the nominal LHC beams is two times 362 MJ, 100 times the energy of the Tevatron. As little as 1 mJ/cm3 deposited energy quenches a magnet at 7 TeV and 1 J/cm3 causes magnet damage. The beam dumps are the only places to safely dispose of this beam. One of the key systems for machine protection is the beam loss monitoring (BLM) system. About 3600 ionization chambers are installed at likely or critical loss locations around the LHC ring. The losses are integrated in 12 time intervals ranging from 40 μs to 84 s and compared to threshold values defined in 32 energy ranges. A beam abort is requested when potentially dangerous losses are detected or when any of the numerous internal system validation tests fails. In addition, loss data are used for machine set-up and operational verifications. The collimation system for example uses the loss data for set-up and regular performance verification. Commissioning and operational experience of the BLM are presented: The machine protection functionality of the BLM system has been fully reliable; the LHC availability has not been compromised by false beam aborts.

  7. Anatomical Changes and Audiological Profile in Branchio-oto-renal Syndrome: A Literature Review

    Directory of Open Access Journals (Sweden)

    Lindau, Tâmara Andrade

    2014-01-01

    Full Text Available Introduction Branchio-oto-renal (BOR syndrome is an autosomal-dominant genetic condition with high penetrance and variable expressivity, with an estimated prevalence of 1 in 40,000. Approximately 40% of the patients with the syndrome have mutations in the gene EYA1, located at chromosomal region 8q13.3, and 5% have mutations in the gene SIX5 in chromosome region 19q13. The phenotype of this syndrome is characterized by preauricular fistulas; structural malformations of the external, middle, and inner ears; branchial fistulas; renal disorders; cleft palate; and variable type and degree of hearing loss. Aim Hearing loss is part of BOR syndrome phenotype. The aim of this study was to present a literature review on the anatomical aspects and audiological profile of BOR syndrome. Data Synthesis Thirty-four studies were selected for analysis. Some aspects when specifying the phenotype of BOR syndrome are controversial, especially those issues related to the audiological profile in which there was variability on auditory standard, hearing loss progression, and type and degree of the hearing loss. Mixed loss was the most common type of hearing loss among the studies; however, there was no consensus among studies regarding the degree of the hearing loss.

  8. Minocycline attenuates noise-induced hearing loss in rats.

    Science.gov (United States)

    Zhang, Jing; Song, Yong-Li; Tian, Ke-Yong; Qiu, Jian-Hua

    2017-02-03

    Noise-induced hearing loss (NIHL) is a serious health concern and prevention of hair cell death or therapeutic intervention at the early stage of NIHL is critical to preserve hearing. Minocycline is a semi-synthetic derivative of tetracycline and has been shown to have otoprotective effects in ototoxic drug-induced hearing impairment, however, whether minocycline can protect against NIHL has not been investigated. The present study demonstrated elevated ABR (auditory brainstem response) thresholds and outer hair cell loss following traumatic noise exposure, which was mitigated by intraperitoneal administration of minocycline (45mg/kg/d) for 5 consecutive days. In conclusion, the present study demonstrated that minocycline, a clinically approved drug with a good safety profile, can attenuate NIHL in rats and may potentially be used for treatment of hearing loss in clinic. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  9. Updates in weight loss surgery and gastrointestinal peptides

    DEFF Research Database (Denmark)

    Svane, Maria Saur; Bojsen-Møller, Kirstine N; Madsbad, Sten

    2015-01-01

    PURPOSE OF REVIEW: Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy are referred to as 'metabolic surgery' due to hormonal shifts with impacts on diabetes remission and weight loss. The purpose of this review is to summarize recent findings in mechanisms underlying beneficial effects...... of weight loss surgery. RECENT FINDINGS: Importantly, gut hormone secretion is altered after RYGB and sleeve gastrectomy due to accelerated transit of nutrients to distal parts of the small intestine, leading to excessive release of L-cell peptide hormones [e.g. glucagon-like peptide-1 (GLP-1), peptide YY......; as demonstrated by relapse of impaired glucose tolerance in studies blocking the GLP-1 receptor by exendin 9-39, and later after major weight loss increased peripheral insulin sensitivity. Gut hormone secretion changes towards a more anorectic profile and is likely important for less caloric intake and weight...

  10. Diabesity: are weight loss medications effective?

    Science.gov (United States)

    Halpern, Alfredo; Mancini, Marcio C

    2005-01-01

    Weight reduction has been shown to improve glycemic control and cardiovascular risk factors associated with insulin resistance in obese individuals with type 2 diabetes mellitus. Therapeutic options for these patients include promoting weight loss (non-pharmacologic and pharmacologic treatment) and improving glycemic control, as well as treating common associated risk factors such as arterial hypertension and dyslipidemias. This article provides an overview of anti-obesity drugs used in the treatment of obese individuals with type 2 diabetes. The most widely investigated drugs, sibutramine and orlistat, result in modest, clinically worthwhile weight loss, with demonstrable improvements in many co-morbidities, among them, type 2 diabetes. Clinical trials with these anti-obesity medications in cohorts of obese diabetic patients have been reviewed as well as cathecolaminergic agents (diethylpropion [amfepramone], fenproporex, mazindol, ephedrine-caffeine combination), serotoninergic drugs (fenfluramine, dexfenfluramine, fluoxetine), and other drugs that have some action on weight loss (the antidiabetic agent metformin, anti-epileptic agents topiramate and zonisamide, and the antidepressive bupropion [amfebutamone]). These trials show variable benefits in terms of effects on glucose profiles.

  11. Beam Loss in Linacs

    CERN Document Server

    Plum, M.A.

    2016-01-01

    Beam loss is a critical issue in high-intensity accelerators, and much effort is expended during both the design and operation phases to minimize the loss and to keep it to manageable levels. As new accelerators become ever more powerful, beam loss becomes even more critical. Linacs for H- ion beams, such as the one at the Oak Ridge Spallation Neutron Source, have many more loss mechanisms compared to H+ (proton) linacs, such as the one being designed for the European Spallation Neutron Source. Interesting H- beam loss mechanisms include residual gas stripping, H+ capture and acceleration, field stripping, black-body radiation and the recently discovered intra-beam stripping mechanism. Beam halo formation, and ion source or RF turn on/off transients, are examples of beam loss mechanisms that are common for both H+ and H- accelerators. Machine protection systems play an important role in limiting the beam loss.

  12. Adaptive neuro-fuzzy inference system for temperature and humidity profile retrieval from microwave radiometer observations

    Science.gov (United States)

    Ramesh, K.; Kesarkar, A. P.; Bhate, J.; Venkat Ratnam, M.; Jayaraman, A.

    2015-01-01

    The retrieval of accurate profiles of temperature and water vapour is important for the study of atmospheric convection. Recent development in computational techniques motivated us to use adaptive techniques in the retrieval algorithms. In this work, we have used an adaptive neuro-fuzzy inference system (ANFIS) to retrieve profiles of temperature and humidity up to 10 km over the tropical station Gadanki (13.5° N, 79.2° E), India. ANFIS is trained by using observations of temperature and humidity measurements by co-located Meisei GPS radiosonde (henceforth referred to as radiosonde) and microwave brightness temperatures observed by radiometrics multichannel microwave radiometer MP3000 (MWR). ANFIS is trained by considering these observations during rainy and non-rainy days (ANFIS(RD + NRD)) and during non-rainy days only (ANFIS(NRD)). The comparison of ANFIS(RD + NRD) and ANFIS(NRD) profiles with independent radiosonde observations and profiles retrieved using multivariate linear regression (MVLR: RD + NRD and NRD) and artificial neural network (ANN) indicated that the errors in the ANFIS(RD + NRD) are less compared to other retrieval methods. The Pearson product movement correlation coefficient (r) between retrieved and observed profiles is more than 92% for temperature profiles for all techniques and more than 99% for the ANFIS(RD + NRD) technique Therefore this new techniques is relatively better for the retrieval of temperature profiles. The comparison of bias, mean absolute error (MAE), RMSE and symmetric mean absolute percentage error (SMAPE) of retrieved temperature and relative humidity (RH) profiles using ANN and ANFIS also indicated that profiles retrieved using ANFIS(RD + NRD) are significantly better compared to the ANN technique. The analysis of profiles concludes that retrieved profiles using ANFIS techniques have improved the temperature retrievals substantially; however, the retrieval of RH by all techniques considered in this paper (ANN, MVLR and

  13. Mission-profile based multi-objective optimization of power electronics converter for wind turbines

    DEFF Research Database (Denmark)

    Gohil, Ghanshyamsinh; Teodorescu, Remus; Kerekes, Tamas

    2017-01-01

    -objective optimization approach for designing power converter is presented. The objective is to minimize the energy loss for a given load profile as against the conventional approach of minimizing power loss at specific loading conditions. The proposed approach is illustrated by designing a grid-side power converter...

  14. Attribution of irreversible loss to anthropogenic climate change

    Science.gov (United States)

    Huggel, Christian; Bresch, David; Hansen, Gerrit; James, Rachel; Mechler, Reinhard; Stone, Dáithí; Wallimann-Helmer, Ivo

    2016-04-01

    The Paris Agreement (2015) under the UNFCCC has anchored loss and damage in a separate article which specifies that understanding and support should be enhanced in areas addressing loss and damage such as early warning, preparedness, insurance and resilience. Irreversible loss is a special category under loss and damage but there is still missing clarity over what irreversible loss actually includes. Many negative impacts of climate change may be handled or mitigated by existing risk management, reduction and absorption approaches. Irreversible loss, however, is thought to be insufficiently addressed by risk management. Therefore, countries potentially or actually affected by irreversible loss are calling for other measures such as compensation, which however is highly contested in international climate policy. In Paris (2015) a decision was adopted that loss and damage as defined in the respective article of the agreement does not involve compensation and liability. Nevertheless, it is likely that some sort of mechanism will eventually need to come into play for irreversible loss due to anthropogenic climate change, which might involve compensation, other forms of non-monetary reparation, or transformation. Furthermore, climate litigation has increasingly been attempted to address negative effects of climate change. In this context, attribution is important to understand the drivers of change, what counts as irreversible loss due to climate change, and, possibly, who or what is responsible. Here we approach this issue by applying a detection and attribution perspective on irreversible loss. We first analyze detected climate change impacts as assessed in the IPCC Fifth Assessment Report. We distinguish between irreversible loss in physical, biological and human systems, and accordingly identify the following candidates of irreversible loss in these systems: loss of glaciers and ice sheets, loss of subsurface ice (permafrost) and related loss of lake systems; loss

  15. Effect of dietary patterns differing in carbohydrate and fat content on blood lipid and glucose profiles based on weight-loss success of breast-cancer survivors.

    Science.gov (United States)

    Thompson, Henry J; Sedlacek, Scot M; Paul, Devchand; Wolfe, Pamela; McGinley, John N; Playdon, Mary C; Daeninck, Elizabeth A; Bartels, Sara N; Wisthoff, Mark R

    2012-01-06

    Healthy body weight is an important factor for prevention of breast cancer recurrence. Yet, weight loss and weight gain are not currently included in clinical-practice guidelines for posttreatment of breast cancer. The work reported addresses one of the questions that must be considered in recommending weight loss to patients: does it matter what diet plan is used, a question of particular importance because breast cancer treatment can increase risk for cardiovascular disease. Women who completed treatment for breast cancer were enrolled in a nonrandomized, controlled study investigating effects of weight loss achieved by using two dietary patterns at the extremes of macronutrient composition, although both diet arms were equivalent in protein: high fat, low carbohydrate versus low fat, high carbohydrate. A nonintervention group served as the control arm; women were assigned to intervention arms based on dietary preferences. During the 6-month weight-loss program, which was menu and recipe defined, participants had monthly clinical visits at which anthropometric data were collected and fasting blood was obtained for safety monitoring for plasma lipid profiles and fasting glucose. Results from 142 participants are reported. Adverse effects on fasting blood lipids or glucose were not observed in either dietary arm. A decrease in fasting glucose was observed with progressive weight loss and was greater in participants who lost more weight, but the effect was not statistically significant, even though it was observed across both diet groups (P = 0.21). Beneficial effects of weight loss on cholesterol (4.7%; P = 0.001), triglycerides (21.8%; P = 0.01), and low-density lipoprotein (LDL) cholesterol (5.8%; P = 0.06) were observed in both groups. For cholesterol (P = 0.07) and LDL cholesterol (P = 0.13), greater reduction trends were seen on the low-fat diet pattern; whereas, for triglycerides (P = 0.01) and high-density lipoprotein (HDL) cholesterol (P = 0.08), a decrease

  16. ITER SAFETY TASK NID-5D: Operational tritium loss and accident investigation for heat transport and water detritiation systems

    International Nuclear Information System (INIS)

    Kalyanam, K.M.; Fong, C.; Moledina, M.; Natalizio, A.

    1995-02-01

    The task objectives are to: a) determine major pathways for tritium loss during normal operation of the cooling systems and water detritiation system, b) estimate operational losses and environmental tritium releases from the heat transport and water detritiation systems of ITER, and c) prepare a preliminary Failure Modes and Effects Analysis (FMEA) for the ITER Water Detritiation System. The analysis will be used to estimate chronic environmental tritium releases (airborne and waterborne) for the ITER Cooling Systems and Water Detritiation System. The assessment will form the basis for demonstrating the acceptability of ITER for siting in the Early Safety and Environmental Characterization Study (ESECS), to be issued in early 1995. (author). 7 refs., 10 tabs., 11 figs

  17. AGS BOOSTER BEAM POSITION, TUNE, AND LONGITUDINAL PROFILE DATA ACQUISITION SYSTEM

    International Nuclear Information System (INIS)

    BROWN, K.A.; AHRENS, L.; SEVERINO, F; SMITH, K.; WILINSKI, M

    2003-01-01

    In this paper we will describe a data acquisition system designed and developed for the AGS Booster. The system was motivated by the need to get high quality beam diagnostics from the AGS Booster. This was accomplished by locating the electronics and digital data acquisition close to the Booster ring, to minimize loss of bandwidth in the original signals. In addition we had to develop the system rapidly and at a low cost. The system consists of a Lecroy digital oscilloscope which is interfaced through a National Instruments LabView(trademark) server application, developed for this project. This allows multiple client applications to time share the scope without interfering with each other. We will present a description of the system design along with example clients that we have implemented

  18. Leak detection and localization system through acoustics; Sistema de deteccao e localizacao de vazamentos por acustica

    Energy Technology Data Exchange (ETDEWEB)

    Alonso, Julio [Aselco Automacao, Sao Paulo, SP (Brazil)

    2003-07-01

    Acoustic Leak Detection Systems (ALDS) are used on both liquid and gas pipelines as well as multi-phase flow pipelines to detect leaks quickly and provide a means of limiting product loss. The real-time acoustic signal is continuously compared against signature leak profiles for the particular operating and geometric conditions. These profiles were developed from a database established from over 20 years of experimental and field leak tests. This technique not only drastically reduces the false alarm rate, but also significantly improves the sensitivity and leak location accuracy. This system will also detect leaks with shut-in flow (zero flow rate in the pipeline). With the use of GPS (Global Positioning System) it not only improves leak location accuracy, but also allows for continuous leak detection during the loss of communications. (author)

  19. Relationship Between Soil Characteristics and Rate of Soil Loss on Coffee Base-Farming System at Sumberjaya, West Lampung

    OpenAIRE

    DARIAH, AI; AGUS, F; ARSYAD, S; SUDARSONO,; MASWAR,

    2003-01-01

    The current public perception concerning land use change is, whenever forest is converted to agricultural land, the forest functions would drasticaly decrease. Studies have shown that soil loss in coffee based systems varied widely and it could be much lower than the tolerable soil loss level, depending on soil properties. This research was conducted to determine the dominant factors of soil properties in influencing soil loss. This analysis was based on data collected from a 3-site (Laksana,...

  20. Stabilization of a Wireless Networked Control System with Packet Loss and Time Delay: An ADS Approach

    Directory of Open Access Journals (Sweden)

    Jing Wang

    2012-01-01

    Full Text Available The stabilization problem of a wireless networked control system is considered in this paper. Both time delay and packet loss exist simultaneously in the wireless network. The system is modeled as an asynchronous dynamic system (ADS with unstable subsystems. A sufficient condition for the system to be stable is presented. A numerical example is given to demonstrate the effectiveness of the proposed approach.

  1. Reliability of the beam loss monitors system for the large hadron collider at CERN

    International Nuclear Information System (INIS)

    Guaglio, G.

    2005-12-01

    The energy stored in the Large Hadron Collider is unprecedented. The impact of the beam particles can cause severe damage on the superconductive magnets, resulting in significant downtime for repairing. The Beam Loss Monitors System (BLMS) detects the secondary particles shower of the lost beam particles and initiates the extraction of the beam before any serious damage to the equipment can occur. This thesis defines the BLMS specifications in term of reliability. The main goal is the design of a system minimizing both the probability to not detect a dangerous loss and the number of false alarms generated. The reliability theory and techniques utilized are described. The prediction of the hazard rates, the testing procedures, the Failure Modes Effects and Criticalities Analysis and the Fault Tree Analysis have been used to provide an estimation of the probability to damage a magnet, of the number of false alarms and of the number of generated warnings. The weakest components in the BLMS have been pointed out. The reliability figures of the BLMS have been calculated using a commercial software package (Isograph.). The effect of the variation of the parameters on the obtained results has been evaluated with a sensitivity analysis. The reliability model has been extended by the results of radiation tests. Design improvements, like redundant optical transmission, have been implemented in an iterative process. The proposed system is compliant with the reliability requirements. The model uncertainties are given by the limited knowledge of the thresholds levels of the superconductive magnets and of the locations of the losses along the ring. The implemented model allows modifications of the system, following the measuring of the hazard rates during the LHC life. It can also provide reference numbers to other accelerators which will implement similar technologies. (author)

  2. LHC Beam Loss Monitoring System Verification Applications

    CERN Document Server

    Dehning, B; Zamantzas, C; Jackson, S

    2011-01-01

    The LHC Beam Loss Mon­i­tor­ing (BLM) sys­tem is one of the most com­plex in­stru­men­ta­tion sys­tems de­ployed in the LHC. In ad­di­tion to protecting the col­lid­er, the sys­tem also needs to pro­vide a means of di­ag­nos­ing ma­chine faults and de­liv­er a feed­back of loss­es to the control room as well as to sev­er­al sys­tems for their setup and analysis. It has to trans­mit and pro­cess sig­nals from al­most 4’000 mon­i­tors, and has near­ly 3 mil­lion con­fig­urable pa­ram­e­ters. The system was de­signed with re­li­a­bil­i­ty and avail­abil­i­ty in mind. The spec­i­fied op­er­a­tion and the fail-safe­ty stan­dards must be guar­an­teed for the sys­tem to per­form its func­tion in pre­vent­ing su­per­con­duc­tive mag­net de­struc­tion caused by par­ti­cle flux. Main­tain­ing the ex­pect­ed re­li­a­bil­i­ty re­quires ex­ten­sive test­ing and ver­i­fi­ca­tion. In this paper we re­port our most re­cent ad­di­t...

  3. Economic information from Smart Meter: Nexus Between Demand Profile and Electricity Retail Price Between Demand Profile and Electricity Retail Price

    OpenAIRE

    Yu, Yang; Liu, Guangyi; Zhu, Wendong; Wang, Fei; Shu, Bin; Zhang, Kai; Rajagopal, Ram; Astier, Nicolas

    2016-01-01

    In this paper, we demonstrate that a consumer's marginal system impact is only determined by their demand profile rather than their demand level. Demand profile clustering is identical to cluster consumers according to their marginal impacts on system costs. A profile-based uniform-rate price is economically efficient as real-time pricing. We develop a criteria system to evaluate the economic efficiency of an implemented retail price scheme in a distribution system by comparing profile cluste...

  4. Genetic profiles of gastroesophageal cancer: combined analysis using expression array and tiling array--comparative genomic hybridization

    DEFF Research Database (Denmark)

    Isinger-Ekstrand, Anna; Johansson, Jan; Ohlsson, Mattias

    2010-01-01

    We aimed to characterize the genomic profiles of adenocarcinomas in the gastroesophageal junction in relation to cancers in the esophagus and the stomach. Profiles of gains/losses as well as gene expression profiles were obtained from 27 gastroesophageal adenocarcinomas by means of 32k high......15, 13q34, and 12q13, whereas different profiles with gains at 5p15, 7p22, 2q35, and 13q34 characterized gastric cancers. CDK6 and EGFR were identified as putative target genes in cancers of the esophagus and the gastroesophageal junction, with upregulation in one quarter of the tumors. Gains....../losses and gene expression profiles show strong similarity between cancers in the distal esophagus and the gastroesophageal junction with frequent upregulation of CDK6 and EGFR, whereas gastric cancer displays distinct genetic changes. These data suggest that molecular diagnostics and targeted therapies can...

  5. Performance profiling for brachytherapy applications

    Science.gov (United States)

    Choi, Wonqook; Cho, Kihyeon; Yeo, Insung

    2018-05-01

    In many physics applications, a significant amount of software (e.g. R, ROOT and Geant4) is developed on novel computing architectures, and much effort is expended to ensure the software is efficient in terms of central processing unit (CPU) time and memory usage. Profiling tools are used during the evaluation process to evaluate the efficiency; however, few such tools are able to accommodate low-energy physics regions. To address this limitation, we developed a low-energy physics profiling system in Geant4 to profile the CPU time and memory of software applications in brachytherapy applications. This paper describes and evaluates specific models that are applied to brachytherapy applications in Geant4, such as QGSP_BIC_LIV, QGSP_BIC_EMZ, and QGSP_BIC_EMY. The physics range in this tool allows it to be used to generate low energy profiles in brachytherapy applications. This was a limitation in previous studies, which caused us to develop a new profiling tool that supports profiling in the MeV range, in contrast to the TeV range that is supported by existing high-energy profiling tools. In order to easily compare the profiling results between low-energy and high-energy modes, we employed the same software architecture as that in the SimpliCarlo tool developed at the Fermilab National Accelerator Laboratory (FNAL) for the Large Hadron Collider (LHC). The results show that the newly developed profiling system for low-energy physics (less than MeV) complements the current profiling system used for high-energy physics (greater than TeV) applications.

  6. A novel antiproton radial diagnostic based on octupole induced ballistic loss

    International Nuclear Information System (INIS)

    Andresen, G. B.; Bowe, P. D.; Hangst, J. S.; Bertsche, W.; Butler, E.; Charlton, M.; Humphries, A. J.; Jenkins, M. J.; Joergensen, L. V.; Madsen, N.; Werf, D. P. van der; Bray, C. C.; Chapman, S.; Fajans, J.; Povilus, A.; Wurtele, J. S.; Cesar, C. L.; Lambo, R.; Silveira, D. M.; Fujiwara, M. C.

    2008-01-01

    We report results from a novel diagnostic that probes the outer radial profile of trapped antiproton clouds. The diagnostic allows us to determine the profile by monitoring the time history of antiproton losses that occur as an octupole field in the antiproton confinement region is increased. We show several examples of how this diagnostic helps us to understand the radial dynamics of antiprotons in normal and nested Penning-Malmberg traps. Better understanding of these dynamics may aid current attempts to trap antihydrogen atoms

  7. A novel antiproton radial diagnostic based on octupole induced ballistic loss

    CERN Document Server

    Andresen, G.B.; Bowe, P.D.; Bray, C.C.; Butler, E.; Cesar, C.L.; Chapman, S.; Charlton, M.; Fajans, J.; Fujiwara, M.C.; Funakoshi, R.; Gill, D.R.; Hangst, J.S.; Hardy, W.N.; Hayano, R.S.; Hayden, M.E.; Humphries, A.J.; Hydomako, R.; Jenkins, M.J.; Jorgensen, L.V.; Kurchaninov, L.; Lambo, R.; Madsen, N.; Nolan, P.; Olchanski, K.; Olin, A.; Page, R.D.; Povilus, A.; Pusa, P.; Robicheaux, F.; Sarid, E.; Seif El Nasr, S.; Silveira, D.M.; Storey, J.W.; Thompson, R.I.; van der Werf, D.P.; Wurtele, J.S.; Yamazaki, Y.

    2008-01-01

    We report results from a novel diagnostic that probes the outer radial profile of trapped antiproton clouds. The diagnostic allows us to determine the profile by monitoring the time-history of antiproton losses that occur as an octupole field in the antiproton confinement region is increased. We show several examples of how this diagnostic helps us to understand the radial dynamics of antiprotons in normal and nested Penning-Malmberg traps. Better understanding of these dynamics may aid current attempts to trap antihydrogen atoms.

  8. Calculation of abort thresholds for the Beam Loss Monitoring System of the Large Hadron Collider at CERN

    CERN Document Server

    Nemcic, Martin; Dehning, Bernd

    The Beam Loss Monitoring (BLM) System is one of the most critical machine protection systems for the Large Hadron Collider (LHC) at the European Organization for Nuclear Research (CERN), Switzerland. Its main purpose is to protect the superconducting magnets from quenches and other equipment from damage by requesting a beam abort when the measured losses exceed any of the predefined threshold levels. The system consist of circa 4000 ionization chambers which are installed around the 27 kilometres ring (LHC). This study aims to choose a technical platform and produce a system that addresses all of the limitations with the current system that is used for the calculation of the LHC BLM abort threshold values. To achieve this, a comparison and benchmarking of the Java and .NET technical platforms is performed in order to establish the most suitable solution. To establish which technical platform is a successful replacement of the current abort threshold calculator, comparable prototype systems in Java and .NET we...

  9. Automatic tuning of Bragg condition in a radio-acoustic system for PBL temperature profile measurement

    Energy Technology Data Exchange (ETDEWEB)

    Bonino, G; Trivero, P

    1985-01-01

    A Radio-Acoustic Sounding System (RASS) with acoustic wavelength lambda/sub a/ approx. 1m was designed and successfully tested. The system proved to be capable of measuring the vertical temperature profile in the Planetary Boundary Layer (PBL) with an accuracy and vertical resolution comparable to that of traditional apparatus (radiothermosondes borne by tethered or disposable balloons, thermosondes borne by aircraft and so on), yet combined with the advantages typical of remote sensing techniques. Up to the summer of 1983 the system needed attendance by an operator who had to identify the acoustic sounding frequency affording the fundamental condition of Bragg resonance between acoustic and radio wavelengths. Features and performance of the new completely automatic RASS arrangement are presented. These include the possibility of obtaining average thermal vertical profiles at preset time intervals. Maximum range of the possibility of obtaining average thermal vertical profiles at preset time intervals. Maximum range of measurements obtained in about 1000 1/2-h averages was: in 90% of cases greater than or equal to 600 m; in 50% of cases greater than or equal to 1100m. Such results indicate the usefulness of automatic RASS as a tool for meteorological purposes and for the application of air pollution control strategies.

  10. RELAP5/MOD 3.2 Analysis of the Loss of RHR System Experiment Scaled to NPP Krsko

    International Nuclear Information System (INIS)

    Bencik, V.; Bajs, T.; Prah, M.

    1998-01-01

    In the paper the RELAP5/MOD 3.2 analysis of the loss of Residual Heat Removal (RHR) system during midloop operation experiment performed at the Rig of Safety Assessment (ROSA)-IV/Large Scale Test Facility (LSTF) together with the analysis of the same test scenario scaled to NPP Krsko are presented. The experiment consisted in a loss of the RHR system at cold shutdown conditions along with a 5% cold leg break in the loop without pressurizer. The Safety Injection (SI) system was disable in the calculation. The aims of the work were to study the physical phenomena encountered under low power and low system pressure conditions while the upper part of the Reactor Coolant System (RCS) is filled with noncondensable. The impact of the bypass flow between upper plenum and downcomer inlet on transient responses was investigated. The transient was simulated for 6000 s. (author)

  11. Microscopic image processing system for measuring nonuniform film thickness profiles: Image scanning ellipsometry

    International Nuclear Information System (INIS)

    Liu, A.H.; Plawsky, J.L.; Wayner, P.C. Jr.

    1993-01-01

    The long-term objective of this research program is to determine the stability and heat transfer characteristics of evaporating thin films. The current objective is to develop and use a microscopic image-processing system (IPS) which has two parts: an image analyzing interferometer (IAI) and an image scanning ellipsometer (ISE). The primary purpose of this paper is to present the basic concept of ISE, which is a novel technique to measure the two dimensional thickness profile of a non-uniform, thin film, from several nm up to several μm, in a steady state as well as in a transient state. It is a full-field imaging technique which can study every point on the surface simultaneously with high spatial resolution and thickness sensitivity, i.e., it can measure and map the 2-D film thickness profile. The ISE was tested by measuring the thickness profile and the refractive index of a nonuniform solid film

  12. Analysis of plasma microRNA expression profiles in male textile workers with noise-induced hearing loss.

    Science.gov (United States)

    Ding, Lu; Liu, Jing; Shen, Huan-Xi; Pan, Li-Ping; Liu, Qing-Dong; Zhang, Heng-Dong; Han, Lei; Shuai, Li-Guo; Ding, En-Min; Zhao, Qiu-Ni; Wang, Bo-Shen; Zhu, Bao-Li

    2016-03-01

    Circulating microRNAs (miRNAs) have attracted interests as non-invasive biomarkers of physiological and pathological conditions, which may be applied in noise-induced hearing loss (NIHL). However, no epidemiology studies have yet examined the potential effects of NIHL or noise exposure on miRNA expression profiles. We sought to identify permanent NIHL-related miRNAs and to predict the biological functions of the putative genes encoding the indicated miRNAs. In the discovery stage, we used a microarray assay to detect the miRNA expression profiles between pooled plasma samples from 10 noise-exposed individuals with normal hearing and 10 NIHL patients. In addition, we conducted a preliminary validation of six candidate miRNAs in the same 20 workers. Subsequently, three miRNAs were selected for expanded validation in 23 non-exposed individuals with normal hearing and 46 noise-exposed textile workers which including 23 noise-exposed workers with normal hearing and 23 NIHL patients. Moreover, we predicted the biological functions of the putative target genes using a Gene Ontology (GO) function enrichment analysis. In the discovery stage, compared with the noise exposures with normal hearing, 73 miRNAs demonstrated at least a 1.5-fold differential expression in the NIHL patients. In the preliminary validation, compared with the noise exposures, the plasma levels of miR-16-5p, miR-24-3p, miR-185-5p and miR-451a were all upregulated (P < 0.001) in the NIHL patients. In the expanded validation stage, compared with the non-exposures, the plasma levels of miR-24, miR-185-5p and miR-451a were all significantly downregulated (P < 0.001) in the exposures. And compared with the noise exposures, the plasma levels of miR-185-5p and miR-451a were slightly elevated (P < 0.001) in the NIHL patients, which were consistent with the results of preliminary validation and microarray analysis. The two indicated plasma miRNAs may be biomarkers of indicating responses to noise exposure

  13. Micronutrient Gaps in Three Commercial Weight-Loss Diet Plans

    Directory of Open Access Journals (Sweden)

    Matthew G. Engel

    2018-01-01

    Full Text Available Weight-loss diets restrict intakes of energy and macronutrients but overlook micronutrient profiles. Commercial diet plans may provide insufficient micronutrients. We analyzed nutrient profiles of three plans and compared their micronutrient sufficiency to Dietary Reference Intakes (DRIs for male U.S. adults. Hypocaloric vegan (Eat to Live-Vegan, Aggressive Weight Loss; ETL-VAWL, high-animal-protein low-carbohydrate (Fast Metabolism Diet; FMD and weight maintenance (Eat, Drink and Be Healthy; EDH diets were evaluated. Seven single-day menus were sampled per diet (n = 21 menus, 7 menus/diet and analyzed for 20 micronutrients with the online nutrient tracker CRON-O-Meter. Without adjustment for energy intake, the ETL-VAWL diet failed to provide 90% of recommended amounts for B12, B3, D, E, calcium, selenium and zinc. The FMD diet was low (<90% DRI in B1, D, E, calcium, magnesium and potassium. The EDH diet met >90% DRIs for all but vitamin D, calcium and potassium. Several micronutrients remained inadequate after adjustment to 2000 kcal/day: vitamin B12 in ETL-VAWL, calcium in FMD and EDH and vitamin D in all diets. Consistent with previous work, micronutrient deficits are prevalent in weight-loss diet plans. Special attention to micronutrient rich foods is required to reduce risk of micronutrient deficiency in design of commercial diets.

  14. Plasma Exosome Profiling of Cancer Patients by a Next Generation Systems Biology Approach.

    Science.gov (United States)

    Domenyuk, Valeriy; Zhong, Zhenyu; Stark, Adam; Xiao, Nianqing; O'Neill, Heather A; Wei, Xixi; Wang, Jie; Tinder, Teresa T; Tonapi, Sonal; Duncan, Janet; Hornung, Tassilo; Hunter, Andrew; Miglarese, Mark R; Schorr, Joachim; Halbert, David D; Quackenbush, John; Poste, George; Berry, Donald A; Mayer, Günter; Famulok, Michael; Spetzler, David

    2017-02-20

    Technologies capable of characterizing the full breadth of cellular systems need to be able to measure millions of proteins, isoforms, and complexes simultaneously. We describe an approach that fulfils this criterion: Adaptive Dynamic Artificial Poly-ligand Targeting (ADAPT). ADAPT employs an enriched library of single-stranded oligodeoxynucleotides (ssODNs) to profile complex biological samples, thus achieving an unprecedented coverage of system-wide, native biomolecules. We used ADAPT as a highly specific profiling tool that distinguishes women with or without breast cancer based on circulating exosomes in their blood. To develop ADAPT, we enriched a library of ~10 11 ssODNs for those associating with exosomes from breast cancer patients or controls. The resulting 10 6 enriched ssODNs were then profiled against plasma from independent groups of healthy and breast cancer-positive women. ssODN-mediated affinity purification and mass spectrometry identified low-abundance exosome-associated proteins and protein complexes, some with known significance in both normal homeostasis and disease. Sequencing of the recovered ssODNs provided quantitative measures that were used to build highly accurate multi-analyte signatures for patient classification. Probing plasma from 500 subjects with a smaller subset of 2000 resynthesized ssODNs stratified healthy, breast biopsy-negative, and -positive women. An AUC of 0.73 was obtained when comparing healthy donors with biopsy-positive patients.

  15. Racetrack resonator as a loss measurement platform for photonic components.

    Science.gov (United States)

    Jones, Adam M; DeRose, Christopher T; Lentine, Anthony L; Starbuck, Andrew; Pomerene, Andrew T S; Norwood, Robert A

    2015-11-02

    This work represents the first complete analysis of the use of a racetrack resonator to measure the insertion loss of efficient, compact photonic components. Beginning with an in-depth analysis of potential error sources and a discussion of the calibration procedure, the technique is used to estimate the insertion loss of waveguide width tapers of varying geometry with a resulting 95% confidence interval of 0.007 dB. The work concludes with a performance comparison of the analyzed tapers with results presented for four taper profiles and three taper lengths.

  16. Ethanol consumption and pineal melatonin daily profile in rats.

    Science.gov (United States)

    Peres, Rafael; do Amaral, Fernanda Gaspar; Madrigrano, Thiago Cardoso; Scialfa, Julieta Helena; Bordin, Silvana; Afeche, Solange Castro; Cipolla-Neto, José

    2011-10-01

    It is well known that melatonin participates in the regulation of many important physiological functions such as sleep-wakefulness cycle, motor coordination and neural plasticity, and cognition. However, as there are contradictory results regarding the melatonin production diurnal profile under alcohol consumption, the aim of this paper was to study the phenomenology and mechanisms of the putative modifications on the daily profile of melatonin production in rats submitted to chronic alcohol intake. The present results show that rats receiving 10% ethanol in drinking water for 35 days display an altered daily profile of melatonin production, with a phase delay and a reduction in the nocturnal peak. This can be partially explained by a loss of the daily rhythm and the 25% reduction in tryptophan hydroxylase activity and, mainly, by a phase delay in arylalkylamine N-acetyltransferase gene expression and a 70% reduction in its peak activity. Upstream in the melatonin synthesis pathway, the results showed that noradrenergic signaling is impaired as well, with a decrease in β1 and α1 adrenergic receptors' mRNA contents and in vitro sustained loss of noradrenergic-stimulated melatonin production by glands from alcohol-treated rats. Together, these results confirm the alterations in the daily melatonin profile of alcoholic rats and suggest the possible mechanisms for the observed melatonin synthesis modification. © 2011 The Authors, Addiction Biology © 2011 Society for the Study of Addiction.

  17. Reliability of the Beam Loss Monitors System for the Large Hadron Collider at CERN

    CERN Document Server

    Guaglio, G; Santoni, C

    2005-01-01

    The energy stored in the Large Hadron Collider is unprecedented. The impact of the beam particles can cause severe damage on the superconductive magnets, resulting in significant downtime for repairing. The Beam Loss Monitors System (BLMS) detects the secondary particles shower of the lost beam particles and initiates the extraction of the beam before any serious damage to the equipment can occur. This thesis defines the BLMS specifications in term of reliability. The main goal is the design of a system minimizing both the probability to not detect a dangerous loss and the number of false alarms generated. The reliability theory and techniques utilized are described. The prediction of the hazard rates, the testing procedures, the Failure Modes Effects and Criticalities Analysis and the Fault Tree Analysis have been used to provide an estimation of the probability to damage a magnet, of the number of false alarms and of the number of generated warnings. The weakest components in the BLMS have been pointed out....

  18. Energy-dependent losses in pulsed-feedback preamplifiers

    International Nuclear Information System (INIS)

    Landis, D.A.; Madden, N.W.; Goulding, F.S.

    1978-11-01

    Energy dependent counting losses occur in most pulsed-feedback preamplifiers due to the loss of those pulses which activate the recharge system. A pulsed-feedback system that overcomes this inefficiency is described. Pulsed-light feedback as used with germanium gamma-ray spectrometers is discussed as used at high energies and high rates where those losses become significant. Experimental results are presented

  19. [Systemic inflammatory profile of smokers with and without COPD].

    Science.gov (United States)

    Mosrane, Y; Bougrida, M; Alloui, A S; Martani, M; Rouabah, L; Bourahli, M K; Mehdioui, H; Ben Saad, H

    2017-09-01

    Studies comparing the systemic inflammatory profiles of smokers with and without COPD present discordant findings. To compare the systemic inflammatory profile of smokers with and without COPD. This is a cross-sectional comparative study. Two groups of active smokers of more than 10 pack-years were included: 56 consecutives stable COPD (postbronchodilator FEV 1 /FVCnon-COPD (postbronchodilator FEV 1 /FVC≥0.70). Smoking and clinical, anthropometric and spirometric data were noted. The following blood biomarkers were identified: leukocytes, hemoglobin, tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR). According to the levels (normal/abnormal) of these markers, two groups of smokers were formed. Quantitative and qualitative data were expressed, respectively, as means±SD and percentages. Compared to the non-COPD group, the COPD group was older (56±12 vs. 65±8 years) and had a higher smoking consumption (30±18 vs. 52±31 pack-years). Compared to the non-COPD group, the COPD group had higher values of CRP (2.06±1.24 vs. 11.32±11.03mg/L), of ESR (9.59±8.29 vs. 15.96±11.56), of IL-6 (9.28±4.69 vs. 20.27±5.31ng/L) and of TNF-α (18.38±7.98ng/L vs. 8.62±3.72ng/L). Compared to the non-COPD group, the COPD group included higher percentages of smokers with elevated CRP (0 % vs. 32 %), with leukocytosis (6 % vs. 16 %), with higher levels of IL-6 (81 % vs. 98 %) or TNF-α (91 % vs. 100 %). Smokers with COPD, compared to smokers free from COPD, have a marked systemic inflammation. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  20. Effective Loss Minimization and Allocation of Unbalanced Distribution Network

    Directory of Open Access Journals (Sweden)

    Manvir Kaur

    2017-11-01

    Full Text Available An efficient distribution network must be able to supply power with good voltage profile. The main objective of the proposed work is to allocate losses of the unbalanced distribution network by the firefly algorithm in regulated and deregulated environments before and after loss minimization. Reconfiguration is one of the methods for loss reduction of unbalanced distribution network. Further, optimal placement of distributed generation and capacitor in the reconfigured unbalanced distribution network can further reduce the loss. The results of reconfigured unbalanced distribution network in regulated environment have already been reported. In this paper reconfiguration of an unbalanced distribution network in a deregulated environment is also carried out using an established Fuzzy Firefly algorithm. Loss sensitivity factor of unbalanced distribution networks is used to get the appropriate location of distributed generation and capacitor to be placed in the unbalanced distribution network. Their ratings have been found out by using bacteria foraging optimization algorithm (BFOA. The suggested loss allocation method using Firefly algorithm is implemented at first on 13 node unbalanced distribution network to check the performance of the proposed loss allocation method when compared to other available method. Finally the proposed method has been implemented on 25 node unbalanced distribution network. Both of the implementations are carried out under MATLAB environment.

  1. Reliability analysis based on the losses from failures.

    Science.gov (United States)

    Todinov, M T

    2006-04-01

    The conventional reliability analysis is based on the premise that increasing the reliability of a system will decrease the losses from failures. On the basis of counterexamples, it is demonstrated that this is valid only if all failures are associated with the same losses. In case of failures associated with different losses, a system with larger reliability is not necessarily characterized by smaller losses from failures. Consequently, a theoretical framework and models are proposed for a reliability analysis, linking reliability and the losses from failures. Equations related to the distributions of the potential losses from failure have been derived. It is argued that the classical risk equation only estimates the average value of the potential losses from failure and does not provide insight into the variability associated with the potential losses. Equations have also been derived for determining the potential and the expected losses from failures for nonrepairable and repairable systems with components arranged in series, with arbitrary life distributions. The equations are also valid for systems/components with multiple mutually exclusive failure modes. The expected losses given failure is a linear combination of the expected losses from failure associated with the separate failure modes scaled by the conditional probabilities with which the failure modes initiate failure. On this basis, an efficient method for simplifying complex reliability block diagrams has been developed. Branches of components arranged in series whose failures are mutually exclusive can be reduced to single components with equivalent hazard rate, downtime, and expected costs associated with intervention and repair. A model for estimating the expected losses from early-life failures has also been developed. For a specified time interval, the expected losses from early-life failures are a sum of the products of the expected number of failures in the specified time intervals covering the

  2. Differences in sheep and goats milk fatty acid profile between conventional and organic farming systems.

    Science.gov (United States)

    Tsiplakou, Eleni; Kotrotsios, Vaios; Hadjigeorgiou, Ioannis; Zervas, George

    2010-08-01

    The objective of this study was to investigate whether there is a difference in chemical composition and particularly in fatty acid (FA) profile, with emphasis on cis-9, trans-11 CLA, of milk obtained from conventional and organic dairy sheep and goats farms under the farming conditions practiced in Greece. Four dairy sheep and four dairy goat farms, representing common conventional production systems and another four dairy sheep and four dairy goat farms, organically certified, representing organic production and feeding systems were selected from all over Greece. One hundred and sixty two individual milk samples were collected from those farms in January-February 2009, about three months after parturition. The milk samples were analyzed for their main chemical constituents and their FA profile. The results showed that the production system affected milk chemical composition: in particular fat content was lower in the organic sheep and goats milk compared with the corresponding conventional. Milk from organic sheep had higher content in MUFA, PUFA, alpha-LNA, cis-9, trans-11 CLA, and omega-3 FA, whereas in milk from organic goats alpha-LNA and omega-3 FA content was higher than that in conventional one. These differences are, mainly, attributed to different feeding practices used by the two production systems. The results of this study show that the organic milk produced under the farming conditions practiced in Greece has higher nutritional value, due to its FA profile, compared with the respective conventional milk.

  3. Persistent weight loss with a non-invasive novel medical device to change eating behaviour in obese individuals with high-risk cardiovascular risk profile.

    Directory of Open Access Journals (Sweden)

    Peter von Seck

    Full Text Available In evidence-based weight-loss programs weight regain is common after an initial weight reduction. Eating slowly significantly lowers meal energy intake and hunger ratings. Despite this knowledge, obese individuals do not implement this behaviour. We, thus tested the hypothesis of changing eating behaviour with an intra-oral medical device leading to constant weight reduction in overweight and obesity. Six obese patients (6 men, age 56 ± 14, BMI 29 ± 2 kg / m2 with increased CVRF profile were included in this prospective study. All patients had been treated for obesity during the last 10 years in a single centre and had at least 3 frustrate evidence-based diets. Patients received a novel non-invasive intra-oral medical device to slow eating time. Further advice included not to count calories, to avoid any other form of diet, to take their time with their meals, and to eat whatever they liked. This device was used only during meals for the first 4 to 8 weeks for a total of 88 [20-160] hours. Follow-up period was 23 [15-38] months. During this period, patients lost 11% [5-20%] (p5%, and 67% (4/6 achieved a >10% bodyweight loss. In the course of the study, altered eating patterns were observed. There were no complications with the medical device. Of note, all patients continued to lose weight after the initial intervention period (p<0.001 and none of them had weight regain. With this medical device, overweight and obese patients with a history of previously frustrating attempts to lose weight achieved a significant and sustained weight loss over two years. These results warrant the ongoing prospective randomised controlled trial to prove concept and mechanism of action.German Clinical Trials Register DRKS00011357.

  4. Design of an O-mode frequency modulated reflectometry system for the measurement of Alborz Tokamak plasma density profile

    Energy Technology Data Exchange (ETDEWEB)

    Koohestani, Saeideh [Department of Energy Engineering and physics, Amirkabir University of Technology, Tehran, 15875-4413, Islamic Republic of Iran (Iran, Islamic Republic of); Amrollahi, Reza, E-mail: amrollahi@aut.ac.ir [Department of Energy Engineering and physics, Amirkabir University of Technology, Tehran, 15875-4413, Islamic Republic of Iran (Iran, Islamic Republic of); Moradi, Gholamreza [Department of Electrical Engineering, Amirkabir University of Technology, Tehran, 15875-4413, Islamic Republic of Iran (Iran, Islamic Republic of)

    2016-12-15

    Reflectometry is a common method for plasma diagnostic, in which microwaves are launched into the plasma and reflected at the critical surfaces. Comparing the reflected microwave signals with the launched waves would give rise to the plasma density profiles. In the present study, an ordinary mode (O-mode) frequency modulation (FM) reflectometry system has been designed for the electron density profile measurement of the Alborz Tokamak plasma. This system has been considered to operate at K-band (18–26.5 GHz) frequency range and scan the frequency band between 18 to 26 GHz in 40 μS. The density profile from major radius r = 47.9–51.55 cm can be measured in Alborz Tokamak plasma. Based on the Alborz Tokamak operational conditions, the characteristic frequencies, and some dimensional limitations, all parts of reflectometer have been designed so that an appropriate efficiency with minimum attenuation, especially in transmitting/receiving system would be achieved. A dual antenna and an oversized waveguide of X-band (8–12 GHz) for transmitting and receiving purposes and a balanced detector for absolute phase determination have been utilized. The details of the Alborz Tokamak FM reflectometry components focusing on the antenna and waveguide design and mounting are described in this paper. Additionally, the procedure of plasma profile reconstruction using the system output signal is discussed. This system uses signal phase shift to determine the position of the cutoff layer.

  5. Electron density profile reconstruction by maximum entropy method with multichannel HCN laser interferometer system on SPAC VII

    International Nuclear Information System (INIS)

    Kubo, S.; Narihara, K.; Tomita, Y.; Hasegawa, M.; Tsuzuki, T.; Mohri, A.

    1988-01-01

    A multichannel HCN laser interferometer system has been developed to investigate the plasma electron confinement properties in SPAC VII device. Maximum entropy method is applied to reconstruct the electron density profile from measured line integrated data. Particle diffusion coefficient in the peripheral region of the REB ring core spherator was obtained from the evolution of the density profile. (author)

  6. BEAP profiles as rapid test system for status analysis and early detection of process incidents in biogas plants.

    Science.gov (United States)

    Refai, Sarah; Berger, Stefanie; Wassmann, Kati; Hecht, Melanie; Dickhaus, Thomas; Deppenmeier, Uwe

    2017-03-01

    A method was developed to quantify the performance of microorganisms involved in different digestion levels in biogas plants. The test system was based on the addition of butyrate (BCON), ethanol (ECON), acetate (ACON) or propionate (PCON) to biogas sludge samples and the subsequent analysis of CH 4 formation in comparison to control samples. The combination of the four values was referred to as BEAP profile. Determination of BEAP profiles enabled rapid testing of a biogas plant's metabolic state within 24 h and an accurate mapping of all degradation levels in a lab-scale experimental setup. Furthermore, it was possible to distinguish between specific BEAP profiles for standard biogas plants and for biogas reactors with process incidents (beginning of NH 4 + -N inhibition, start of acidification, insufficient hydrolysis and potential mycotoxin effects). Finally, BEAP profiles also functioned as a warning system for the early prediction of critical NH 4 + -N concentrations leading to a drop of CH 4 formation.

  7. Dielectric loss against piezoelectric power harvesting

    Science.gov (United States)

    Liang, Junrui; Shu-Hung Chung, Henry; Liao, Wei-Hsin

    2014-09-01

    Piezoelectricity is one of the most popular electromechanical transduction mechanisms for constructing kinetic energy harvesting systems. When a standard energy harvesting (SEH) interface circuit, i.e., bridge rectifier plus filter capacitor, is utilized for collecting piezoelectric power, the previous literature showed that the power conversion can be well predicted without much consideration for the effect of dielectric loss. Yet, as the conversion power gets higher by adopting power-boosting interface circuits, such as synchronized switch harvesting on inductor (SSHI), the neglect of dielectric loss might give rise to deviation in harvested power estimation. Given the continuous progress on power-boosting interface circuits, the role of dielectric loss in practical piezoelectric energy harvesting (PEH) systems should receive attention with better evaluation. Based on the integrated equivalent impedance network model, this fast track communication provides a comprehensive study on the susceptibility of harvested power in PEH systems under different conditions. It shows that, dielectric loss always counteracts piezoelectric power harvesting by causing charge leakage across piezoelectric capacitance. In particular, taking corresponding ideal lossless cases as references, the counteractive effect might be aggravated under one of the five conditions: larger dielectric loss tangent, lower vibration frequency, further away from resonance, weaker electromechanical coupling, or using power-boosting interface circuit. These relationships are valuable for the study of PEH systems, as they not only help explain the role of dielectric loss in piezoelectric power harvesting, but also add complementary insights for material, structure, excitation, and circuit considerations towards holistic evaluation and design for practical PEH systems.

  8. Dielectric loss against piezoelectric power harvesting

    International Nuclear Information System (INIS)

    Liang, Junrui; Shu-Hung Chung, Henry; Liao, Wei-Hsin

    2014-01-01

    Piezoelectricity is one of the most popular electromechanical transduction mechanisms for constructing kinetic energy harvesting systems. When a standard energy harvesting (SEH) interface circuit, i.e., bridge rectifier plus filter capacitor, is utilized for collecting piezoelectric power, the previous literature showed that the power conversion can be well predicted without much consideration for the effect of dielectric loss. Yet, as the conversion power gets higher by adopting power-boosting interface circuits, such as synchronized switch harvesting on inductor (SSHI), the neglect of dielectric loss might give rise to deviation in harvested power estimation. Given the continuous progress on power-boosting interface circuits, the role of dielectric loss in practical piezoelectric energy harvesting (PEH) systems should receive attention with better evaluation. Based on the integrated equivalent impedance network model, this fast track communication provides a comprehensive study on the susceptibility of harvested power in PEH systems under different conditions. It shows that, dielectric loss always counteracts piezoelectric power harvesting by causing charge leakage across piezoelectric capacitance. In particular, taking corresponding ideal lossless cases as references, the counteractive effect might be aggravated under one of the five conditions: larger dielectric loss tangent, lower vibration frequency, further away from resonance, weaker electromechanical coupling, or using power-boosting interface circuit. These relationships are valuable for the study of PEH systems, as they not only help explain the role of dielectric loss in piezoelectric power harvesting, but also add complementary insights for material, structure, excitation, and circuit considerations towards holistic evaluation and design for practical PEH systems. (fast track communications)

  9. From profile to sawtooth control: developing feedback control using ECRH/ECCD systems on the TCV tokamak

    International Nuclear Information System (INIS)

    Paley, J I; Felici, F; Coda, S; Goodman, T P

    2009-01-01

    Real time control of heating systems is essential to maximize plasma performance and avoid or neutralize instabilities under changing plasma conditions. Several feedback control algorithms have been developed on the Tokamak a Configuration Variable (TCV) tokamak that use the electron cyclotron (ECRH/ECCD) system to control a wide range of plasma properties, including the plasma current, shape, profiles as well as the sawtooth instability. Controllers have been developed to obtain sawteeth of a pre-determined period, to maximize the sawtooth period using an extremum seeking control algorithm and finally to provide simultaneous control of the plasma emission profile peak and width using multiple independent EC actuators.

  10. The differential plasma proteome of obese and overweight individuals undergoing a nutritional weight loss and maintenance intervention

    DEFF Research Database (Denmark)

    Oller Moreno, Sergio; Cominetti, Ornella; Núñez Galindo, Antonio

    2018-01-01

    PURPOSE: The nutritional intervention program "DiOGenes" focuses on how obesity can be prevented and treated from a dietary perspective. We generated differential plasma proteome profiles in the DiOGenes cohort to identify proteins associated with weight loss and maintenance and explore their rel......PURPOSE: The nutritional intervention program "DiOGenes" focuses on how obesity can be prevented and treated from a dietary perspective. We generated differential plasma proteome profiles in the DiOGenes cohort to identify proteins associated with weight loss and maintenance and explore...... with largest changes were sex hormone-binding globulin, adiponectin, C-reactive protein, calprotectin, serum amyloid A, and proteoglycan 4 (PRG4), whose association with obesity and weight loss is known. We identified new putative biomarkers for weight loss/maintenance. Correlation between PRG4 and proline......-rich acidic protein 1 (PRAP1) variation and Matsuda insulin sensitivity increment was showed. CONCLUSIONS AND CLINICAL RELEVANCE: MS-based proteomic analysis of a large cohort of non-diabetic overweight and obese individuals concomitantly identified known and novel proteins associated with weight loss...

  11. Voltage regulation and power losses reduction in a wind farm integrated MV distribution network

    Science.gov (United States)

    Fandi, Ghaeth; Igbinovia, Famous Omar; Tlusty, Josef; Mahmoud, Rateb

    2018-01-01

    A medium-voltage (MV) wind production system is proposed in this paper. The system applies a medium-voltage permanent magnet synchronous generator (PMSG) as well as MV interconnection and distribution networks. The simulation scheme of an existing commercial electric-power system (Case A) and a proposed wind farm with a gearless PMSG insulated gate bipolar transistor (IGBT) power electronics converter scheme (Case B) is compared. The analyses carried out in MATLAB/Simulink environment shows an enhanced voltage profile and reduced power losses, thus, efficiency in installed IGBT power electronics devices in the wind farm. The resulting wind energy transformation scheme is a simple and controllable medium voltage application since it is not restrained by the IGBT power electronics voltage source converter (VSC) arrangement. Active and reactive power control is made possible with the aid of the gearless PMSG IGBT power converters.

  12. Environmental cost of distribution transformer losses

    International Nuclear Information System (INIS)

    Georgilakis, Pavlos S.

    2011-01-01

    Improvements in energy efficiency of electrical equipment reduce the greenhouse gas (GHG) emissions and contribute to the protection of the environment. Moreover, as system investment and energy costs continue to increase, electric utilities are increasingly interested in installing energy-efficient transformers at their distribution networks. This paper analyzes the impact of the environmental cost of transformer losses on the economic evaluation of distribution transformers. This environmental cost is coming form the cost to buy GHG emission credits because of the GHG emissions associated with supplying transformer losses throughout the transformer lifetime. Application results on the Hellenic power system for 21 transformer offers under 9 different scenarios indicate that the environmental cost of transformer losses can reach on average 34% and 8% of transformer purchasing price for high loss and medium loss transformers, respectively. That is why it is important to incorporate the environmental cost of transformer losses into the economic evaluation of distribution transformers.

  13. Colony fusion and worker reproduction after queen loss in army ants

    DEFF Research Database (Denmark)

    Kronauer, Daniel J C; Schöning, Caspar; d'Ettorre, Patrizia

    2010-01-01

    their reproductive success. We show that worker chemical recognition profiles remain similar after queen loss, but rapidly change into a mixed colony Gestalt odour after fusion, consistent with indiscriminate acceptance of alien workers that are no longer aggressive. We hypothesize that colony fusion after queen...

  14. A simple method to determine evaporation and compensate for liquid losses in small-scale cell culture systems.

    Science.gov (United States)

    Wiegmann, Vincent; Martinez, Cristina Bernal; Baganz, Frank

    2018-04-24

    Establish a method to indirectly measure evaporation in microwell-based cell culture systems and show that the proposed method allows compensating for liquid losses in fed-batch processes. A correlation between evaporation and the concentration of Na + was found (R 2  = 0.95) when using the 24-well-based miniature bioreactor system (micro-Matrix) for a batch culture with GS-CHO. Based on these results, a method was developed to counteract evaporation with periodic water additions based on measurements of the Na + concentration. Implementation of this method resulted in a reduction of the relative liquid loss after 15 days of a fed-batch cultivation from 36.7 ± 6.7% without volume corrections to 6.9 ± 6.5% with volume corrections. A procedure was established to indirectly measure evaporation through a correlation with the level of Na + ions in solution and deriving a simple formula to account for liquid losses.

  15. [Effect of reduced N application on soil N residue and N loss in maize-soybean relay strip intercropping system].

    Science.gov (United States)

    Liu, Xiao-Ming; Yong, Tai-Wen; Liu, Wen-Yu; Su, Ben-Ying; Song, Chun; Yang, Feng; Wang, Xiao-Chun; Yang, Wen-Yu

    2014-08-01

    A field experiment was conducted in 2012, including three planting pattern (maize-soybean relay strip intercropping, mono-cultured maize and soybean) and three nitrogen application level [0 kg N x hm(-2), 180 kg N x hm(-2) (reduced N) and 240 kg N x hm(-2) (normal N)]. Fields were assigned to different treatments in a randomized block design with three replicates. The objective of this work was to analyze the effects of planting patterns and nitrogen application rates on plant N uptake, soil N residue and N loss. After fertilization applications, NH4(+)-N and NO3(-)-N levels increased in the soil of intercropped maize but decreased in the soil of intercropped soybean. Compared with mono-crops, the soil N residue and loss of intercropped soybean were reduced, while those of intercropped maize were increased and decreased, respectively. With the reduced rate of N application, N residue rate, N loss rate and ammonia volatilization loss rate of the maize-soybean intercropping relay strip system were decreased by 17.7%, 21.5% and 0.4% compared to mono-cultured maize, but increased by 2.0%, 19.8% and 0.1% compared to mono-cultured soybean, respectively. Likewise, the reduced N application resulted in reductions in N residue, N loss, and the N loss via ammonia volatilization in the maize-soybean relay strip intercropping system compared with the conventional rate of N application adopted by local farmers, and the N residue rate, N loss rate and ammonia volatilization loss rate reduced by 12.0%, 15.4% and 1.2%, respectively.

  16. Minimization of distribution system losses by exploiting storage and anticipating market-driven behaviour of wind power producers

    NARCIS (Netherlands)

    Farrokhseresht, M.; Paterakis, N.G.; Gibescu, M.; Slootweg, J.G.

    2017-01-01

    This paper presents a stochastic bi-level optimization model to determine the optimal dispatch of energy storage systems controlled directly by the distribution system operator (DSO) in order to achieve minimization of active power losses, taking into account the profit-driven participation of

  17. Temperature Profile in Fuel and Tie-Tubes for Nuclear Thermal Propulsion Systems

    Energy Technology Data Exchange (ETDEWEB)

    Vishal Patel

    2015-02-01

    A finite element method to calculate temperature profiles in heterogeneous geometries of tie-tube moderated LEU nuclear thermal propulsion systems and HEU designs with tie-tubes is developed and implemented in MATLAB. This new method is compared to previous methods to demonstrate shortcomings in those methods. Typical methods to analyze peak fuel centerline temperature in hexagonal geometries rely on spatial homogenization to derive an analytical expression. These methods are not applicable to cores with tie-tube elements because conduction to tie-tubes cannot be accurately modeled with the homogenized models. The fuel centerline temperature directly impacts safety and performance so it must be predicted carefully. The temperature profile in tie-tubes is also important when high temperatures are expected in the fuel because conduction to the tie-tubes may cause melting in tie-tubes, which may set maximum allowable performance. Estimations of maximum tie-tube temperature can be found from equivalent tube methods, however this method tends to be approximate and overly conservative. A finite element model of heat conduction on a unit cell can model spatial dependence and non-linear conductivity for fuel and tie-tube systems allowing for higher design fidelity of Nuclear Thermal Propulsion.

  18. Evaporation rates and surface profiles on heterogeneous surfaces with mass transfer and surface reaction

    Energy Technology Data Exchange (ETDEWEB)

    Flytzani-Stephanopoulos, M; Schmidt, L D

    1979-01-01

    Simple models incorporating surface reaction and diffusion of volatile products through a boundary layer are developed to calculate effective rates of evaporation and local surface profiles on surfaces having active and inactive regions. The coupling between surface heterogeneities with respect to a particular reaction and external mass transfer may provide a mechanism for the surface rearrangement and metal loss encountered in several catalytic systems of practical interest. Calculated transport rates for the volatilization of platinum in oxidizing environments and the rearrangement of this metal during the ammonia oxidation reaction agree well with published experimental data.

  19. Emotion regulation reduces loss aversion and decreases amygdala responses to losses.

    Science.gov (United States)

    Sokol-Hessner, Peter; Camerer, Colin F; Phelps, Elizabeth A

    2013-03-01

    Emotion regulation strategies can alter behavioral and physiological responses to emotional stimuli and the neural correlates of those responses in regions such as the amygdala or striatum. The current study investigates the brain systems engaged when using an emotion regulation technique during financial decisions. In decision making, regulating emotion with reappraisal-focused strategies that encourage taking a different perspective has been shown to reduce loss aversion as observed both in choices and in the relative arousal responses to actual loss and gain outcomes. In the current study, we find using fMRI that behavioral loss aversion correlates with amygdala activity in response to losses relative to gains. Success in regulating loss aversion also correlates with the reduction in amygdala responses to losses but not to gains. Furthermore, across both decisions and outcomes, we find the reappraisal strategy increases baseline activity in dorsolateral and ventromedial prefrontal cortex and the striatum. The similarity of the neural circuitry observed to that seen in emotion regulation, despite divergent tasks, serves as further evidence for a role of emotion in decision making, and for the power of reappraisal to change assessments of value and thereby choices.

  20. Upregulation of gene expression in reward-modulatory striatal opioid systems by sleep loss.

    Science.gov (United States)

    Baldo, Brian A; Hanlon, Erin C; Obermeyer, William; Bremer, Quentin; Paletz, Elliott; Benca, Ruth M

    2013-12-01

    Epidemiological studies have shown a link between sleep loss and the obesity 'epidemic,' and several observations indicate that sleep curtailment engenders positive energy balance via increased palatable-food 'snacking.' These effects suggest alterations in reward-modulatory brain systems. We explored the effects of 10 days of sleep deprivation in rats on the expression of striatal opioid peptide (OP) genes that subserve food motivation and hedonic reward, and compared effects with those seen in hypothalamic energy balance-regulatory systems. Sleep-deprived (Sleep-Dep) rats were compared with yoked forced-locomotion apparatus controls (App-Controls), food-restricted rats (Food-Restrict), and unmanipulated controls (Home-Cage). Detection of mRNA levels with in situ hybridization revealed a subregion-specific upregulation of striatal preproenkephalin and prodynorhin gene expression in the Sleep-Dep group relative to all other groups. Neuropeptide Y (NPY) gene expression in the hippocampal dentate gyrus and throughout neocortex was also robustly upregulated selectively in the Sleep-Dep group. In contrast, parallel gene expression changes were observed in the Sleep-Dep and Food-Restrict groups in hypothalamic energy-sensing systems (arcuate nucleus NPY was upregulated, and cocaine- and amphetamine-regulated transcript was downregulated), in alignment with leptin suppression in both groups. Together, these results reveal a novel set of sleep deprivation-induced transcriptional changes in reward-modulatory peptide systems, which are dissociable from the energy-balance perturbations of sleep loss or the potentially stressful effects of the forced-locomotion procedure. The recruitment of telencephalic food-reward systems may provide a feeding drive highly resistant to feedback control, which could engender obesity through the enhancement of palatable feeding.

  1. Weight loss predictability by plasma metabolic signatures in adults with obesity and morbid obesity of the DiOGenes study

    DEFF Research Database (Denmark)

    Stroeve, Johanna H M; Saccenti, Edoardo; Bouwman, Jildau

    2016-01-01

    predictive for weight loss were acetoacetate, triacylglycerols, phosphatidylcholines, specific amino acids, and creatine and creatinine. This metabolic profile suggests that high energy metabolism activity results in higher amounts of weight loss. CONCLUSIONS: Possible predictive (pre-diet) markers were...

  2. 38 CFR 4.112 - Weight loss.

    Science.gov (United States)

    2010-07-01

    .... The term “inability to gain weight” means that there has been substantial weight loss with inability... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Weight loss. 4.112... DISABILITIES Disability Ratings The Digestive System § 4.112 Weight loss. For purposes of evaluating conditions...

  3. Match score affects activity profile and skill performance in professional Australian Football players.

    Science.gov (United States)

    Sullivan, Courtney; Bilsborough, Johann C; Cianciosi, Michael; Hocking, Joel; Cordy, Justin; Coutts, Aaron J

    2014-05-01

    To examine the influence of quarter outcome and the margin of the score differential on both the physical activity profile and skill performance of players during professional Australian Football matches. Prospective, longitudinal. Physical activity profiles were assessed via microtechnology (Global Positioning System and accelerometer) from 40 professional AF players from the same team during 15 Australian Football League games. Skill performance measures (involvement and effectiveness) and player rank scores (Champion Data(©) Rank) were provided by a commercial statistical provider. The physical performance variables, skill involvements and individual player performance scores were expressed relative to playing time for each quarter. The influence of the quarter result (i.e. win vs. loss) and score margin (i.e. small: 19 points) on activity profile and skill involvements and skill efficiency performance of players were examined. Skill involvements (total disposals/min, long kicks/min, marks/min, running bounces/min and player rank/min) were greater in quarters won (all p14.5 km h(-1), HSR/min), sprints/min and peak speed were higher in losing quarters (all pProfessional AF players are likely to have an increased physical activity profile and decreased skill involvement and proficiency when their team is less successful. Copyright © 2013 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  4. An altered hormonal profile and elevated rate of bone loss are associated with low bone mass in professional horse-racing jockeys.

    Science.gov (United States)

    Dolan, Eimear; McGoldrick, Adrian; Davenport, Colin; Kelleher, Grainne; Byrne, Brendan; Tormey, William; Smith, Diarmuid; Warrington, Giles D

    2012-09-01

    Horse-racing jockeys are a group of weight-restricted athletes, who have been suggested as undertaking rapid and extreme weight cycling practices in order to comply with stipulated body-mass standards. The aim of this study was to examine bone mass, turnover and endocrine function in jockeys and to compare this group with age, gender and body mass index matched controls. Twenty male professional jockeys and 20 healthy male controls participated. Dual energy X-ray absorptiometry scans and early morning fasting blood and urine samples were used to measure bone mass, turnover and a hormonal profile. Total body bone mineral density (BMD) was significantly lower in jockeys (1.143 ± 0.05 vs. 1.27 ± 0.06 g cm(-3), p professional jockeys have an elevated rate of bone loss and reduced bone mass that appears to be associated with disrupted hormonal activity. It is likely that this may have occurred in response to the chronic weight cycling habitually experienced by this group.

  5. MANAGEMENT OF CREDIT LOSSES

    Directory of Open Access Journals (Sweden)

    Natalya P. Anoshkina

    2018-06-01

    Full Text Available The paper is devoted to the problem of credit loss management topical for modern Russian science and banking practice. The bank’s lending activity is an integral and the most profitable sphere of banking activity. Banks need to take credit risks inherent in their core business and minimize their impact through the establishment of advanced risk management systems. The study, reflected in the present paper, has been conducted in order to determine approaches to the organization of credit loss management in banking. Analysis of the system of management of credit risks and credit losses has shown that they have different scope, object and purpose. In this connection, there is an objective necessity to create a special subsystem for the management of credit losses in banks. On the basis of common bank approaches to credit risk management, the paper develops models of credit loss management: a multi-level management model in the area of ‘operational-tactical-strategic management’ and a functional management model in the area of ‘technology-execution-control’. These models are important for the modern theory and practice of banking, as they allow the bank to manage credit losses on the entire time horizon of the management process, thus opening a wide range of opportunities for the creation and implementation of large-scale programs, as well as specific techniques. This study allows drawing a conclusion about the need to consider control credit losses as a strictly regulated multi-level process, in which each division is assigned with specific objectives, tasks, functions, formally enshrined in the relevant lists, job descriptions and other legal documents.

  6. Secondary superficial siderosis of the central nervous system in a patient presenting with sensorineural hearing loss

    International Nuclear Information System (INIS)

    Lemmerling, M.; De Praeter, G.; Mollet, P.; Mortele, K.; Kunnen, M.; Mastenbroek, G.

    1998-01-01

    We present a 50-year-old man who was investigated for sensorineural hearing loss. On MRI of the brain superficial siderosis of the central nervous system was seen, while MRI of the spine revealed an ependymoma of the cauda equina. This case illustrates the importance of performing T2-weighted imaging of the brain and posterior fossa when sensorineural hearing loss is present. Spine imaging is mandatory when superficial siderosis of the brain is diagnosed without identification of a bleeding source in the brain. (orig.)

  7. Voltage Profile Enhancement and Reduction of Real Power loss by Hybrid Biogeography Based Artificial Bee Colony algorithm

    Directory of Open Access Journals (Sweden)

    K. Lenin

    2014-04-01

    Full Text Available This paper presents Hybrid Biogeography algorithm for solving the multi-objective reactive power dispatch problem in a power system. Real Power Loss minimization and maximization of voltage stability margin are taken as the objectives. Artificial bee colony optimization (ABC is quick and forceful algorithm for global optimization. Biogeography-Based Optimization (BBO is a new-fangled biogeography inspired algorithm. It mainly utilizes the biogeography-based relocation operator to share the information among solutions. In this work, a hybrid algorithm with BBO and ABC is projected, and named as HBBABC (Hybrid Biogeography based Artificial Bee Colony Optimization, for the universal numerical optimization problem. HBBABC merge the searching behavior of ABC with that of BBO. Both the algorithms have different solution probing tendency like ABC have good exploration probing tendency while BBO have good exploitation probing tendency.  HBBABC used to solve the reactive power dispatch problem and the proposed technique has been tested in standard IEEE30 bus test system.

  8. Tax Loss Utilization and Corporate Groups: A Policy Conundrum

    Directory of Open Access Journals (Sweden)

    Stephen R. Richardson

    2013-01-01

    Full Text Available There are both theoretical and practical tax policy considerations that favour a broad recognition for the value of corporate income tax losses-- including for businesses operated within corporate groups. Ideally, an equitable and economically efficient tax system could obviate the need for loss netting against income by providing for the tax value of losses from business to be refundable by tax authorities in cash to owners. This approach, however, involves many serious difficulties, including revenue cost to governments and potential for abuse by both domestic and foreign businesses. Accordingly, loss refundability tends to be provided for only sparingly, if at all; while many corporate income tax systems—such as in the U.S. the U.K., Japan and many other OECD countries--deal with loss netting within corporate groups through a formal system of tax loss transfer or tax consolidation. While Canadian policymakers have considered introduction of such a system over a long period of time, they have yet to come up with a satisfactory formal system for Canada. So, corporate groups in Canada have been left to make do with an informal self-help loss trading system that presents a number of problems compared to formal systems. As a federal country with substantial corporate taxation levied at the provincial level, Canada appears unusually constrained in what it can do to bring greater equity and efficiency to corporate group tax loss utilization. Moreover, the inefficiencies in the current system are small in aggregate terms, and the informal self-help system has a relatively generous threshold for access. Accordingly, while Canada’s current informal self-help corporate group loss system is far from ideal, it appears to remain as a workable approach. Alternatives to the status quo should be considered cautiously, as they have the potential to do more harm than good.

  9. From the SAIN,LIM system to the SENS algorithm: a review of a French approach of nutrient profiling.

    Science.gov (United States)

    Tharrey, Marion; Maillot, Matthieu; Azaïs-Braesco, Véronique; Darmon, Nicole

    2017-08-01

    Nutrient profiling aims to classify or rank foods according to their nutritional composition to assist policies aimed at improving the nutritional quality of foods and diets. The present paper reviews a French approach of nutrient profiling by describing the SAIN,LIM system and its evolution from its early draft to the simplified nutrition labelling system (SENS) algorithm. Considered in 2010 by WHO as the 'French model' of nutrient profiling, SAIN,LIM classifies foods into four classes based on two scores: a nutrient density score (NDS) called SAIN and a score of nutrients to limit called LIM, and one threshold on each score. The system was first developed by the French Food Standard Agency in 2008 in response to the European regulation on nutrition and health claims (European Commission (EC) 1924/2006) to determine foods that may be eligible for bearing claims. Recently, the European regulation (EC 1169/2011) on the provision of food information to consumers allowed simplified nutrition labelling to facilitate consumer information and help them make fully informed choices. In that context, the SAIN,LIM was adapted to obtain the SENS algorithm, a system able to rank foods for simplified nutrition labelling. The implementation of the algorithm followed a step-by-step, systematic, transparent and logical process where shortcomings of the SAIN,LIM were addressed by integrating specificities of food categories in the SENS, reducing the number of nutrients, ordering the four classes and introducing European reference intakes. Through the French example, this review shows how an existing nutrient profiling system can be specifically adapted to support public health nutrition policies.

  10. Microbial Community Profiles in Wastewaters from Onsite Wastewater Treatment Systems Technology.

    Directory of Open Access Journals (Sweden)

    Łukasz Jałowiecki

    Full Text Available The aim of the study was to determine the potential of community-level physiological profiles (CLPPs methodology as an assay for characterization of the metabolic diversity of wastewater samples and to link the metabolic diversity patterns to efficiency of select onsite biological wastewater facilities. Metabolic fingerprints obtained from the selected samples were used to understand functional diversity implied by the carbon substrate shifts. Three different biological facilities of onsite wastewater treatment were evaluated: fixed bed reactor (technology A, trickling filter/biofilter system (technology B, and aerated filter system (the fluidized bed reactor, technology C. High similarities of the microbial community functional structures were found among the samples from the three onsite wastewater treatment plants (WWTPs, as shown by the diversity indices. Principal components analysis (PCA showed that the diversity and CLPPs of microbial communities depended on the working efficiency of the wastewater treatment technologies. This study provided an overall picture of microbial community functional structures of investigated samples in WWTPs and discerned the linkages between microbial communities and technologies of onsite WWTPs used. The results obtained confirmed that metabolic profiles could be used to monitor treatment processes as valuable biological indicators of onsite wastewater treatment technologies efficiency. This is the first step toward understanding relations of technology types with microbial community patterns in raw and treated wastewaters.

  11. New Mexico Look for the STARS--AIM HIGH: QRS Profile. The Child Care Quality Rating System (QRS) Assessment

    Science.gov (United States)

    Child Trends, 2010

    2010-01-01

    This paper presents a profile of New Mexico's Look for the STARS--AIM HIGH prepared as part of the Child Care Quality Rating System (QRS) Assessment Study. The profile consists of several sections and their corresponding descriptions including: (1) Program Information; (2) Rating Details; (3) Quality Indicators for Center-Based Programs; (4)…

  12. Fully automated laser ray tracing system to measure changes in the crystalline lens GRIN profile.

    Science.gov (United States)

    Qiu, Chen; Maceo Heilman, Bianca; Kaipio, Jari; Donaldson, Paul; Vaghefi, Ehsan

    2017-11-01

    Measuring the lens gradient refractive index (GRIN) accurately and reliably has proven an extremely challenging technical problem. A fully automated laser ray tracing (LRT) system was built to address this issue. The LRT system captures images of multiple laser projections before and after traversing through an ex vivo lens. These LRT images, combined with accurate measurements of the lens geometry, are used to calculate the lens GRIN profile. Mathematically, this is an ill-conditioned problem; hence, it is essential to apply biologically relevant constraints to produce a feasible solution. The lens GRIN measurements were compared with previously published data. Our GRIN retrieval algorithm produces fast and accurate measurements of the lens GRIN profile. Experiments to study the optics of physiologically perturbed lenses are the future direction of this research.

  13. Cytokines in systemic lupus erythematosus: far beyond Th1/Th2 dualism lupus: cytokine profiles.

    Science.gov (United States)

    Guimarães, Poliana Macedo; Scavuzzi, Bruna Miglioranza; Stadtlober, Nicole Perugini; Franchi Santos, Lorena Flor da Rosa; Lozovoy, Marcell Alysson Batisti; Iriyoda, Tatiana Mayumi Veiga; Costa, Neide Tomimura; Reiche, Edna Maria Vissoci; Maes, Michael; Dichi, Isaias; Simão, Andréa Name Colado

    2017-10-01

    The aims of this study were to delineate cytokine profiles of systemic lupus erythematosus (SLE), construct prediction models for diagnosis and disease activity using those profiles, and to examine the associations between TNFB Ncol polymorphism, body mass index (BMI) and vitamin D levels with cytokine levels. Two hundred SLE patients and 196 healthy controls participated in this case-control study. Plasma cytokines levels of tumor necrosis factor (TNF)-α, interferon (IFN)-γ, interleukin (IL)-1β, IL- 4, IL-6, IL-10, IL-12 and IL-17 were measured and cytokines profiles were computed. IL-6, IL-12, IL-17, IFN-γ and IL-10 levels were significantly higher in SLE, while IL-4 was lower in SLE. The Th1/Th2 and Th1+Th17/Th2 profiles were significantly higher in SLE than in healthy controls, whereas there were no significant differences in the proinflammatory cytokine profile (TNFα+IL-6+IL-1β). In total, 90.4% of all subjects were correctly classified using Th1+Th17 profile and IL-10 (positively associated) and IL-4 (negatively associated) as predictor variables (sensitivity=66.7% and specificity=96.9%). In all, 20.9% of the variance in the SLE Disease Activity Index was predicted by the Th1+Th17/Th2 ratio, IL-10 and BMI (all positively) and proinflammatory profile (inversely associated). B1/B1 genotype is accompanied by increased IL-17 and Th17/Th2 ratio, while B1/B2 genotype is accompanied by higher IL-4 and IFNγ values. 25-OH vitamin D was inversely associated with IFN-γ levels. SLE is accompanied by Th1, Th17 and Treg profile and lowered IL-4 production. Lowered vitamin D levels and B1/B1 genotype, but not BMI, contribute to changes in cytokines profiles. Future treatments should target Th1, Th2 and Th17 profiles rather than inflammatory cytokines.

  14. Assessing the influence of the temporal resolution of electrical load and PV generation profiles on self-consumption and sizing of PV-battery systems

    International Nuclear Information System (INIS)

    Beck, T.; Kondziella, H.; Huard, G.; Bruckner, T.

    2016-01-01

    Highlights: • MILP optimization model for operation and investment of PV-battery systems. • Use of high resolution (10 s) electrical household load and PV generation profiles. • Analysis of influence of temporal resolution on self-consumption and optimal sizing. • Electrical load profile characteristics influence required temporal resolution. - Abstract: The interest in self-consumption of electricity generated by rooftop photovoltaic systems has grown in recent years, fueled by decreasing levelized costs of electricity and feed-in tariffs as well as increasing end customer electricity prices in the residential sector. This also fostered research on grid-connected PV-battery storage systems, which are a promising technology to increase self-consumption. In this paper a mixed-integer linear optimization model of a PV-battery system that minimizes the total discounted operating and investment costs is developed. The model is employed to study the effect of the temporal resolution of electrical load and PV generation profiles on the rate of self-consumption and the optimal sizing of PV and PV-battery systems. In contrast to previous studies high resolution (10 s) measured input data for both PV generation and electrical load profiles is used for the analysis. The data was obtained by smart meter measurements in 25 different households in Germany. It is shown that the temporal resolution of load profiles is more critical for the accuracy of the determination of self-consumption rates than the resolution of the PV generation. For PV-systems without additional storage accurate results can be obtained by using 15 min solar irradiation data. The required accuracy for the electrical load profiles depends strongly on the load profile characteristics. While good results can be obtained with 60 s for all electrical load profiles, 15 min data can still be sufficient for load profiles that do not exhibit most of their electricity consumption at power levels above 2 k

  15. On a multi-channel transportation loss system with controlled input and controlled service

    Directory of Open Access Journals (Sweden)

    Jewgeni Dshalalow

    1987-01-01

    Full Text Available A multi-channel loss queueing system is investigated. The input stream is a controlled point process. The service in each of m parallel channels depends on the state of the system at certain moments of time when input and service may be controlled. To obtain explicitly the limiting distribution of the main process (Zt (the number of busy channels in equilibrium, an auxiliary three dimensional process with two additional components (one of them is a semi-Markov process is treated as semi-regenerative process. An optimization problem is discussed. Simple expressions for an objective function are derived.

  16. Loss of integrated control system power and overcooling transient at Rancho Seco on December 26, 1985

    International Nuclear Information System (INIS)

    1986-02-01

    On December 26, 1985, Rancho Seco Nuclear Generating Station, located in Clay, California, about 25 miles southeast of Sacramento, experienced a loss of dc power within the integrated control system (ICS) while the plant was operating at 76% power. The plant is owned by the Sacramento Municipal Utility District (SMUD). Following the loss of ICS dc power, the reactor tripped on high reactor coolant system (RCS) pressure followed by a rapid overcooling transient and automatic initiation of the safety features actuation system on low RCS pressure. The overcooling transient continued until ICS dc power was restored 26 minutes after its loss. The fundamental causes for this transient were design weaknesses and vulnerabilities in the ICS and in the equipment controlled by that system. These weaknesses and vulnerabilities were not adequately compensated by other design features, plant procedures or operator training. These weaknesses and vulnerabilities were largely known to SMUD and the NRC staff by virtue of a number of precursor events and through related analyses and studies. Yet, adequate plant modifications were not made so that this event would be improbable, or so that its course or consequences would be altered significantly. The information was available and known which could have prevented this overcooling transient; but in the absence of adequate plant modifications, the incident should have been expected. The report includes findings and conclusions of the NRC Incident Investigation Team sent to Rancho Seco by the NRC Executive Director for Operations in conformance with NRC's recently established Incident Investigation Program. 33 figs

  17. Protecting a full-scale Nb3Sn magnet with CLIQ, the new coupling-loss-induced quench system

    NARCIS (Netherlands)

    Ravaioli, Emanuele; Bajas, H.; Datskov, V.I.; Desbiolles, V.; Feuvrier, J.; Kirby, G.; Maciejewski, M.; Sabbi, G.; ten Kate, Herman H.J.; Verweij, A.P.

    2015-01-01

    A new protection system for superconducting magnets called coupling-loss induced quench system (CLIQ) has been recently developed at CERN. Recent tests on Nb-Ti coils have shown that CLIQ is a valid, efficient, and promising method for the protection of high-magnetic-field superconducting magnets.

  18. Analytical calculations of the rotational transform angles in the torsatron systems with different plasma pressure profiles

    International Nuclear Information System (INIS)

    Kuznetsov, Yu.K.; Pinos, I.B.; Tyupa, V.I.

    1999-01-01

    With formulas for averaging over magnetic surfaces general analytical expressions are here deduced to determine the rotational transform angles in stellarator systems having different plasma pressure profiles

  19. Java project on periodontal diseases: periodontal bone loss in relation to environmental and systemic conditions

    NARCIS (Netherlands)

    Amaliya, A.; Laine, M.L.; Delanghe, J.R.; Loos, B.G.; van Wijk, A.J.; van der Velden, U.

    2015-01-01

    Objective To assess in a population deprived from regular dental care the relationship between alveolar bone loss (ABL) and environmental/systemic conditions. Material & Methods The study population consisted of subjects from the Purbasari tea estate on West Java, Indonesia. A full set of dental

  20. Water Loss in Small Settlements

    OpenAIRE

    Mindaugas Rimeika; Anželika Jurkienė

    2014-01-01

    The main performance indicators of a water supply system include the quality and safety of water, continuous work, relevant pressure and small water loss. The majority of foreign and local projects on reducing water loss have been carried out in the water supply systems of metropolitans; however, the specificity of small settlements differs from that of big cities. Differences can be observed not only in the development of infrastructure and technical indicators but also in the features of wa...

  1. Modeling heat loss from the udder of a dairy cow.

    Science.gov (United States)

    Gebremedhin, Kifle G; Wu, Binxin

    2016-07-01

    A mechanistic model that predicts sensible and latent heat fluxes from the udder of a dairy cow was developed. The prediction of the model was spot validated against measured data from the literature, and the result agreed within 7% of the measured value for the same ambient temperature. A dairy cow can lose a significant amount of heat (388W/m(2)) from the udder. This suggests that the udder could be considered as a heat sink. The temperature profile through the udder tissue (core to skin) approached the core temperature for an air temperature ≥37°C whereas the profile decreased linearly from the core to skin surface for an air temperature less than 37°C. Sensible heat loss was dominant when ambient air temperature was less than 37.5°C but latent heat loss was greater than sensible heat loss when air temperature was ≥37.5°C. The udder could lose a total (sensible + latent) heat flux of 338W/m(2) at an ambient temperature of 35°C and blood-flow rate of 3.2×10(-3)m(3)/(sm(3) tissue). The results of this study suggests that, in time of heat stress, a dairy cow could be cooled by cooling the udder only (e.g., using an evaporative cooling jacket). Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Energy-loss of He ions in carbon allotropes studied by elastic resonance in backscattering spectra

    Energy Technology Data Exchange (ETDEWEB)

    Tosaki, Mitsuo, E-mail: tosaki.mitsuo.3v@kyoto-u.ac.jp [Radioisotope Research Center, Kyoto University, Kyoto 606-8501 (Japan); Rauhala, Eero [Department of Physics, University of Helsinki (Finland)

    2015-10-01

    Backscattering spectra for {sup 4}He ions incident on carbon allotropes have been measured in the energy range from 4.30 to 4.95 MeV in steps of 50–100 keV at scattering angles of 106° and 170°. We used three carbon allotropes: graphite, diamond and amorphous carbon. For all these allotropes, we can observe the sharp ({sup 4}He, {sup 12}C) elastic nuclear resonance at the He ion energy of 4.265 MeV in the backscattering spectra. By varying the incident He energy, we have systematically analyzed the profiles of the resonance peaks to study the energy-loss processes: stopping cross-sections and energy-loss straggling around the interesting region of the stopping maximum at about 500 keV. We focus on the resonance profiles and investigate an allotropic effect concerning the energy-loss. Furthermore, an energy bunching effect on the straggling is presented and the mechanism is discussed.

  3. Stokes profile analysis and vector magnetic fields. I. Inversion of photospheric lines

    International Nuclear Information System (INIS)

    Skumanich, A.; Lites, B.W.

    1987-01-01

    Improvements are proposed for the Auer et al. (1977) method for the analytic inversion of Stokes profiles via nonlinear least squares. The introduction of additional physics into the Mueller absorption matrix (by including damping wings and magnetooptical birefringence, and by decoupling the intensity profile from the three-vector polarization profile in the analysis) is found to result in a more robust inversion method, providing more reliable and accurate estimates of sunspot vector magnetic fields without significant loss of economy. The method is applied to sunspot observations obtained with the High Altitude Observatory polarimeter. 29 references

  4. Phosphorus distribution in sandy soil profile under drip irrigation system

    International Nuclear Information System (INIS)

    El-Gendy, R.W.; Rizk, M.A.; Abd El Moniem, M.; Abdel-Aziz, H.A.; Fahmi, A.E.

    2009-01-01

    This work aims at to studying the impact of irrigation water applied using drip irrigation system in sandy soil with snap bean on phosphorus distribution. This experiment was carried out in soils and water research department farm, nuclear research center, atomic energy authority, cairo, Egypt. Snap bean was cultivated in sandy soil and irrigated with 50,37.5 and 25 cm water in three water treatments represented 100, 75 and 50% ETc. Phosphorus distribution and direction of soil water movement had been detected in three sites on the dripper line (S1,S2 and S3 at 0,12.5 and 25 cm distance from dripper). Phosphorus fertilizer (super phosphate, 15.5% P 2 O 5 in rate 300 kg/fed)was added before cultivation. Neutron probe was used to detect the water distribution and movement at the three site along soil profile. Soil samples were collected before p-addition, at end developing, mid, and late growth stages to determine residual available phosphorus. The obtained data showed that using 50 cm water for irrigation caused an increase in P-concentration till 75 cm depth in the three sites of 100% etc treatment, and covered P-requirements of snap bean for all growth stages. As for 37.5 and 25 cm irrigation water cannot cover all growth stages for P-requirements of snap bean. It could be concluded that applied irrigation water could drive the residual P-levels till 75 cm depth in the three sites. Yield of the crop had been taken as an indicator as an indicator profile. Yield showed good response according to water quantities and P-transportation within the soil profile

  5. Post-Formation Sodium Loss on the Moon: A Bulk Estimate

    Science.gov (United States)

    Saxena, P.; Killen, R. M.; Airapetian, V.; Petro, N. E.; Mandell, A. M.

    2018-01-01

    The Moon and Earth are generally similar in terms of composition, but there exist variations in the abundance of certain elements among the two bodies. These differences are a likely consequence of differing physical evolution of the two bodies over the solar system's history. While previous works have assumed this may be due to conditions during the Moonâ€"TM"s formation, we explore the likelihood that the observed depletion in Sodium in lunar samples may be partially due to post-formation mechanisms. Solar effects, loss from a primordial atmosphere and impacts are some of the dominant post-formation mechanisms that we examine. We describe how our past and current modeling efforts indicate that a significant fraction of the observed depletion of sodium in lunar samples relative to a bulk silicate earth composition may have been due to solar activity, atmospheric loss and impacts. Using profiles of sodium abundances from lunar crustal samples may thus serve as a powerful tool towards exploring conditions on the Moon's surface throughout solar system history. Conditions on the Moon immediately after formation may still be recorded in the lunar crust and may provide a window towards interpreting observations from some of the first rocky exoplanets that will be most amenable to characterization. Potential spatial variation of sodium in the lunar crust may be a relevant consideration for future sample return efforts. Sodium Depletion in the Lunar Crust: Lunar

  6. Vent clearing during a simulated loss-of-coolant accident in a Mark I boiling-water reactor pressure-suppression system

    International Nuclear Information System (INIS)

    Pitts, J.H.; McCauley, E.W.

    1978-01-01

    In this test series, drywell pressurization rate, drywell overpressure, downcomer submergence, and overall vent system loss coefficient were varied to quantify the primary load sensitivities in the pressure suppression system. Extensive tests were conducted on a unique three-dimensional 1/5 scale model of the pressure suppression system a MARK-I BWR. They were focused on the initial or air cleaning phase of a hypothetical loss of coolant accident. As a result of the complete measurement system employed including multiple high speed cameras, the logical interrelationship between measured forces, measured pressures, and the hydrodynamic phenomena observed in high speed photographic pictures were established. The quantitative values from the 1/5 scale experiments can be applied to full scale plants using established scaling laws. (author)

  7. The Analysis of Secondary Motion and Lubrication Performance of Piston considering the Piston Skirt Profile

    Directory of Open Access Journals (Sweden)

    Yanjun Lu

    2018-01-01

    Full Text Available The work performance of piston-cylinder liner system is affected by the lubrication condition and the secondary motion of the piston. Therefore, more and more attention has been paid to the secondary motion and lubrication of the piston. In this paper, the Jakobson-Floberg-Olsson (JFO boundary condition is employed to describe the rupture and reformation of oil film. The average Reynolds equation of skirt lubrication is solved by the finite difference method (FDM. The secondary motion of piston-connecting rod system is modeled; the trajectory of the piston is calculated by the Runge-Kutta method. By considering the inertia of the connecting rod, the influence of the longitudinal and horizontal profiles of piston skirt, the offset of the piston pin, and the thermal deformation on the secondary motion and lubrication performance is investigated. The parabolic longitudinal profile, the smaller top radial reduction and ellipticities of the middle-convex piston, and the bigger bottom radial reduction and ellipticities can effectively reduce the secondary displacement and velocity, the skirt thrust, friction, and the friction power loss. The results show that the connecting rod inertia, piston skirt profile, and thermal deformation have important influence on secondary motion and lubrication performance of the piston.

  8. A new algorithm for optimum voltage and reactive power control for minimizing transmission lines losses

    International Nuclear Information System (INIS)

    Ghoudjehbaklou, H.; Danai, B.

    2001-01-01

    Reactive power dispatch for voltage profile modification has been of interest to power utilities. Usually local bus voltages can be altered by changing generator voltages, reactive shunts, ULTC transformers and SVCs. Determination of optimum values for control parameters, however, is not simple for modern power system networks. Heuristic and rather intelligent algorithms have to be sought. In this paper a new algorithm is proposed that is based on a variant of a genetic algorithm combined with simulated annealing updates. In this algorithm a fuzzy multi-objective a approach is used for the fitness function of the genetic algorithm. This fuzzy multi-objective function can efficiently modify the voltage profile in order to minimize transmission lines losses, thus reducing the operating costs. The reason for such a combination is to utilize the best characteristics of each method and overcome their deficiencies. The proposed algorithm is much faster than the classical genetic algorithm and cna be easily integrated into existing power utilities software. The proposed algorithm is tested on an actual system model of 1284 buses, 799 lines, 1175 fixed and ULTC transformers, 86 generators, 181 controllable shunts and 425 loads

  9. A Fast CVD Diamond Beam Loss Monitor for LHC

    CERN Document Server

    Griesmayer, E; Dobos, D; Effinger, E; Pernegger, H

    2011-01-01

    Chemical Vapour Deposition (CVD) diamond detectors were installed in the collimation area of the CERN LHC to study their feasibility as Fast Beam Loss Monitors in a high-radiation environment. The detectors were configured with a fast, radiation-hard pre-amplifier with a bandwidth of 2 GHz. The readout was via an oscilloscope with a bandwidth of 1 GHz and a sampling rate of 5 GSPS. Despite the 250 m cable run from the detectors to the oscilloscope, single MIPs were resolved with a 2 ns rise time, a pulse width of 10 ns and a time resolution of less than 1 ns. Two modes of operation were applied. For the analysis of unexpected beam aborts, the loss profile was recorded in a 1 ms buffer and, for nominal operation, the histogram of the time structure of the losses was recorded in synchronism with the LHC period of 89.2 μs. Measurements during the LHC start-up (February to December 2010) are presented. The Diamond Monitors gave an unprecedented insight into the time structure of the beam losses resolving the 400...

  10. Nondestructive strain depth profiling with high energy X-ray diffraction: System capabilities and limitations

    Science.gov (United States)

    Zhang, Zhan; Wendt, Scott; Cosentino, Nicholas; Bond, Leonard J.

    2018-04-01

    Limited by photon energy, and penetration capability, traditional X-ray diffraction (XRD) strain measurements are only capable of achieving a few microns depth due to the use of copper (Cu Kα1) or molybdenum (Mo Kα1) characteristic radiation. For deeper strain depth profiling, destructive methods are commonly necessary to access layers of interest by removing material. To investigate deeper depth profiles nondestructively, a laboratory bench-top high-energy X-ray diffraction (HEXRD) system was previously developed. This HEXRD method uses an industrial 320 kVp X-Ray tube and the Kα1 characteristic peak of tungsten, to produces a higher intensity X-ray beam which enables depth profiling measurement of lattice strain. An aluminum sample was investigated with deformation/load provided using a bending rig. It was shown that the HEXRD method is capable of strain depth profiling to 2.5 mm. The method was validated using an aluminum sample where both the HEXRD method and the traditional X-ray diffraction method gave data compared with that obtained using destructive etching layer removal, performed by a commercial provider. The results demonstrate comparable accuracy up to 0.8 mm depth. Nevertheless, higher attenuation capabilities in heavier metals limit the applications in other materials. Simulations predict that HEXRD works for steel and nickel in material up to 200 µm, but experiment results indicate that the HEXRD strain profile is not practical for steel and nickel material, and the measured diffraction signals are undetectable when compared to the noise.

  11. Diagnostic system for measurement of particle balance in TMX-U

    International Nuclear Information System (INIS)

    Allen, S.L.; Correll, D.L.; Hill, D.N.; Wood, R.D.; Brown, M.D.

    1986-01-01

    Several diagnostics measure the particle sources and losses in the Tandem Mirror Experiment-Upgrade (TMX-U) plasma. An absolutely calibrated high-speed (0.5 ms per frame) filtered (6561 A) video camera measures the total ionization source as a function of radius. An axial view of the plasma automatically integrates the axial variations within the depth of field of the system. Another camera, viewing the plasma radially, measures the axial source variations near the deuterium fueling source. Axial ion losses are measured by an array of Faraday cups that are equipped with grids for repelling electrons and are mounted at each end of the experiment. Unequal ion and electron (nonambipolar) radial losses are inferred from net current measurements on an array of grounded plates at each end. Any differences between the measured particle losses and sources may be attributed to ambipolar radial losses and/or azimuthal asymmetries in the particle-loss profiles. Methods of system calibration, along with details of computer data acquisition and processing of this relatively large set of data, are also presented. 6 refs., 1 fig

  12. Reliability and Energy Loss in Full-scale Wind Power Converter Considering Grid Codes and Wind Classes

    DEFF Research Database (Denmark)

    Zhou, Dao; Blaabjerg, Frede; Franke, Toke

    2014-01-01

    With the increasing penetration of the wind power, reliable operation and cost-effective wind energy production are of more and more importance. As one of the promising configurations, the cost on reliability and production losses of permanent-magnet synchronous generator based full-scale wind......, if the specific designed wind turbine system operates at different wind classes, it can be seen that higher wind class level results in lower lifetime of the power converter. In respect to the cost of the reactive power, either the OE or the UE reactive power increases the energy loss per year significantly...... power converter is studied considering the grid code with reactive power production as well as the annual wind profile. Regarding the reliability, it is found that either the Over-Excited (OE) or the Under-Excited (UE) reactive power injection threatens the lifespan under all wind classes. Meanwhile...

  13. Surface profile measurement by using the integrated Linnik WLSI and confocal microscope system

    Science.gov (United States)

    Wang, Wei-Chung; Shen, Ming-Hsing; Hwang, Chi-Hung; Yu, Yun-Ting; Wang, Tzu-Fong

    2017-06-01

    The white-light scanning interferometer (WLSI) and confocal microscope (CM) are the two major optical inspection systems for measuring three-dimensional (3D) surface profile (SP) of micro specimens. Nevertheless, in practical applications, WLSI is more suitable for measuring smooth and low-slope surfaces. On the other hand, CM is more suitable for measuring uneven-reflective and low-reflective surfaces. As for aspect of surface profiles to be measured, the characteristics of WLSI and CM are also different. WLSI is generally used in semiconductor industry while CM is more popular in printed circuit board industry. In this paper, a self-assembled multi-function optical system was integrated to perform Linnik white-light scanning interferometer (Linnik WLSI) and CM. A connecting part composed of tubes, lenses and interferometer was used to conjunct finite and infinite optical systems for Linnik WLSI and CM in the self-assembled optical system. By adopting the flexibility of tubes and lenses, switching to perform two different optical measurements can be easily achieved. Furthermore, based on the shape from focus method with energy of Laplacian filter, the CM was developed to enhance the on focal information of each pixel so that the CM can provide all-in-focus image for performing the 3D SP measurement and analysis simultaneously. As for Linnik WLSI, eleven-step phase shifting algorithm was used to analyze vertical scanning signals and determine the 3D SP.

  14. Acute Vision Loss Following Endoscopic Sinus Surgery

    Directory of Open Access Journals (Sweden)

    Serena Byrd

    2017-01-01

    Full Text Available A 41-year-old female with a history of uterine cancer and Celiac and Raynaud’s Disease presented to our institution with frequent migraines and nasal congestion. She underwent functional endoscopic sinus surgery (FESS and experienced acute unilateral vision loss postoperatively. Rapid recognition of the etiology and effective treatment are paramount given the permanent and irreversible vision loss that can result. Arterial vasospasm following FESS is rare. Patients with autoimmune diseases have perhaps an increased risk for vasospasm secondary to an increased vasoreactive profile. We present the first documented case of nitroglycerin sublingual therapy to successfully treat ophthalmic artery vasospasm following FESS. Nitroglycerin sublingual therapy is a promising treatment for ophthalmic vasospasm secondary to its ability to cross the blood-ocular barrier, its rapid onset of action, and its ability to promote relaxation of vascular smooth muscle.

  15. Interfacing systems LOCAs [Loss of Coolant Accidents] at boiling water reactors

    International Nuclear Information System (INIS)

    Chu, Tsong-Lun; Fitzpatrick, R.; Stoyanov, S.

    1987-01-01

    The work presented in this paper was performed by Brookhaven National Laboratory (BNL) in support of Nuclear Regulatory Commission's (NRC) effort towards the resolution of Generic Issue 105 ''Interfacing System Loss of Coolant Accidents (LOCAs) at Boiling Water Reactors (BWRs).'' For BWRs, intersystem LOCA have typically either not been considered in probabilistic risk analyses, or if considered, were judged to contribute little to the risk estimates because of their perceived low frequency of occurrence. However, recent operating experience indicates that the pressure isolation valves (PIVs) in BWRs may not adequately protect against overpressurization of low pressure systems. The objective of this paper is to present the results of a study which analyzed interfacing system LOCA at several BWRs. The BWRs were selected to best represent a spectrum of BWRs in service using industry operating event experience and plant-specific information/configurations. The results presented here include some possible changes in test requirements/practices as well as an evaluation of their reduction potential in terms of core damage frequency

  16. Response of temperature and density profiles to heat deposition profile and its impact on global scaling in LHD

    International Nuclear Information System (INIS)

    Yamada, H.; Murakami, S.; Yamazaki, K.

    2002-01-01

    Energy confinement and heat transport of net current-free NBI-heated plasmas in the Large Helical Device (LHD) are discussed with an emphasis on density dependence. Although the apparent density dependence of the energy confinement time has been demonstrated in a wide parameter range in LHD, the loss of this dependence has been observed in the high density regime under the specific condition. Broad heat deposition due to off-axis alignment and shallow penetration of neutral beams degrades the global energy confinement while the local heat transport maintains a clear temperature dependence lying between Bohm and gyro-Bohm characteristics. The central heat deposition inclines towards an intrinsic density dependence like τ E ∝(n-bar e /P) 0.6 from the saturated state. The broadening of the temperature profile due to the broad heat deposition profile contrasts with the invariant property which has observed widely as profile consistency and stiffness in tokamak experiments. (author)

  17. Response of temperature and density profiles to heat deposition profile and its impact on global scaling in LHD

    International Nuclear Information System (INIS)

    Yamada, H.; Murakami, S.; Yamazaki, K.

    2003-01-01

    Energy confinement and heat transport of net current-free NBI-heated plasmas in the Large Helical Device (LHD) are discussed with an emphasis on density dependence. Although the apparent density dependence of the energy confinement time has been demonstrated in a wide parameter range in LHD, the loss of this dependence has been observed in the high density regime under the specific condition. Broad heat deposition due to off-axis alignment and shallow penetration of neutral beams degrades the global energy confinement while the local heat transport maintains a clear temperature dependence lying between Bohm and gyro-Bohm characteristics. The central heat deposition inclines towards an intrinsic density dependence like τ E ∝(n-bars e /P) 0.6 from the saturated state. The broadening of the temperature profile due to the broad heat deposition profile contrasts with the invariant property which has observed widely as profile consistency and stiffness in tokamak experiments. (author)

  18. CO2 content of electricity losses

    International Nuclear Information System (INIS)

    Daví-Arderius, Daniel; Sanin, María-Eugenia; Trujillo-Baute, Elisa

    2017-01-01

    Countries are implementing policies to develop greener energy markets worldwide. In Europe, the ¨2030 Energy and Climate Package¨ asks for further reductions of green house gases, renewable sources integration, and energy efficiency targets. But the polluting intensity of electricity may be different in average than when considering market inefficiencies, in particular losses, and therefore the implemented policy must take those differences into account. Precisely, herein we study the importance in terms of CO2 emissions the extra amount of energy necessary to cover losses. With this purpose we use Spanish market and system data with hourly frequency from 2011 to 2013. Our results show that indeed electricity losses significantly explain CO2 emissions, with a higher CO2 emissions rate when covering losses than the average rate of the system. Additionally, we find that the market closing technologies used to cover losses have a positive and significant impact on CO2 emissions: when polluting technologies (coal or combined cycle) close the market, the impact of losses on CO2 emissions is high compared to the rest of technologies (combined heat and power, renewables or hydropower). To the light of these results we make some policy recommendations to reduce the impact of losses on CO2 emissions. - Highlights: • Electricity losses significantly explain CO2 emissions. • Policies aimed to reducing losses have a positive impact on CO2 emissions. • The market closing technology used to cover losses have impacts on CO2 emissions. • Pollutant technologies that close the market should be replaced by renewables.

  19. Urban logistics profile – Yogyakarta city, Indonesia

    Directory of Open Access Journals (Sweden)

    Maria Sri Asih Anna

    2018-01-01

    Full Text Available In recent years, more rural areas are becoming urban areas accompanied by escalation of logistics activities. Unlike passenger transport, the planning, policy and control of freight transport in developing countries have not been integrated into a reliable and efficient logistics system. Therefore, generating city logistics profile is necessary in order to support the planning of urban logistics system. This study aims to establish a logistics profile of Yogyakarta city, Indonesia, by dividing urban zones into several homogeneous groups, judging from several aspects, including city area features, product characteristics and agents/delivery profile. Logistics profile variables were calculated based on administrative boundaries, resulting in 45 areas to be investigated. Profiles were matched in groups of homogeneous stores (A, large commercial stores (C and residential areas with local trade (D,with one overlapping profile, i.e. profile A and profile D, in some locations in the middle of the city.

  20. [MMPI-2 profiles in groups of systemic autoimmune disease - rheumatoid arthritis and systemic lupus erythematosus - patients].

    Science.gov (United States)

    Csókási, Krisztina; Hargitai, Rita; Járai, Róbert; Nagy, László; Czirják, László; Kiss, Enikö Csilla

    2015-01-01

    Systemic autoimmune diseases like rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) are characterized by the alteration of immunological response, which can damage many organs and systems and result in a wide variety of clinical presentations. In addition to physical symptoms, psychiatric disorders are also common to many autoimmune diseases. Anxiety, depression, psychosis and cognitive deficits have the highest prevalence. The aim of this study was to display the degree of psychopathological symptoms in patients with RA and SLE. Female inpatients with RA (N=68) and SLE (N=78) were recruited from the Rheumatology and Immunology Clinic of the University of Pecs and were asked to complete the Minnesota Multiphasic Personality Inventory-2 (MMPI-2) and a short demografical form. The clinical personality profiles of the patient groups were explored and compared with each other. High scores (above 64T) were detected on the Hypochondriasis (Hs), Depression (D) and Hysteria (Hy) scales in both groups. Besides, the participants performed elevated scores on the Masculinity-Feminity (Mf), Psychasthenia (Pt) and Social Introversion (Si) clinical scales. They scored in the elevated range on the Physical Malfunctioning, Subjective Depression, Lassitude-Malaise and Somatic Complaints subscales of the neurotic triad. No significant difference was found on the ten clinical scales between the SLE and RA patients. Characteristics of MMPI-2 profiles in SLE and RA patients seem to be the consequence of the disease and a common feature of chronic conditions. High scores on the neurotic triad scales may reflect the comorbid psychiatric disorders and the somatic symptoms alike, so further investigations with the revised Hungarian MMPI-2 are needed.

  1. Smart Sensing System for Early Detection of Bone Loss: Current Status and Future Possibilities

    Directory of Open Access Journals (Sweden)

    Nasrin Afsarimanesh

    2018-02-01

    Full Text Available Bone loss and osteoporosis is a serious health problem worldwide. The impact of osteoporosis is far greater than many other serious health problems, such as breast and prostate cancers. Statistically, one in three women and one in five men over 50 years of age will experience osteoporotic fractures in their life. In this paper, the design and development of a portable IoT-based sensing system for early detection of bone loss have been presented. The CTx-I biomarker was measured in serum samples as a marker of bone resorption. A planar interdigital sensor was used to evaluate the changes in impedance by any variation in the level of CTx-I. Artificial antibodies were used to introduce selectivity to the sensor for CTx-I molecule. Artificial antibodies for CTx-I molecules were created using molecular imprinted polymer (MIP technique in order to increase the stability of the system and reduce the production cost and complexity of the assay procedure. Real serum samples collected from sheep blood were tested and the result validation was done by using an ELISA kit. The PoC device was able to detect CTx-I concentration as low as 0.09 ng/mL. It exhibited an excellent linear behavior in the range of 0.1–2.5 ng/mL, which covers the normal reference ranges required for bone loss detection. Future possibilities to develop a smart toilet for simultaneous measurement of different bone turnover biomarkers was also discussed.

  2. Effect of high-protein or normal-protein diet on weight loss, body composition, hormone, and metabolic profile in southern Brazilian women with polycystic ovary syndrome: a randomized study.

    Science.gov (United States)

    Toscani, Mariana K; Mario, Fernanda M; Radavelli-Bagatini, Simone; Wiltgen, Denusa; Matos, Maria Cristina; Spritzer, Poli Maria

    2011-11-01

    The aim of the present study was to assess the effects of a high protein (HP) and a normal protein (NP) diet on patients with polycystic ovary syndrome (PCOS) and body mass index-matched controls in a sample of southern Brazilian women. This 8-week randomized trial was carried out at a university gynecological endocrinology clinic and included 18 patients with PCOS and 22 controls. Changes in weight, body composition, hormone, and metabolic profile were analyzed in women randomized to receive HP (30% protein, 40% carbohydrate, and 30% lipid) or NP (15% protein, 55% carbohydrate, and 30% lipid). The energy content was estimated for each participant at 20-25 kcal/kg current weight/day. Physical activity, blood pressure, homeostasis model assessment (HOMA) index, and fasting and 2-h glucose and insulin remained stable during the intervention in PCOS and controls, even in the presence of weight loss. There were no changes in lipid profile in either group. In contrast, body weight, body mass index (BMI), waist circumference, percent of body fat, and sum of trunk skinfolds decreased significantly after both diets in both groups. Total testosterone also decreased in PCOS and controls regardless of diet. In conclusion, calorie reduction, rather than protein content, seemed to affect body composition and hormonal profile in this short-term study. These findings emphasize the role of non-pharmacological interventions to reduce weight and ameliorate the anthropometric and clinical phenotype in PCOS.

  3. EDNA-An expert software system for comparison and evaluation of DNA profiles in forensic casework

    DEFF Research Database (Denmark)

    Haldemann, B.; Dornseifer, S.; Heylen, T.

    2015-01-01

    eDNA is an expert software system for DNA profile comparison, match interpretation and automated report generation in forensic DNA casework. Process automation and intelligent graphical representation maximise reliability of DNA evidence, while facilitating and accelerating the work of DNA experts....

  4. Exposure to bacterial DNA before hemorrhagic shock strongly aggravates systemic inflammation and gut barrier loss via an IFN-gamma-dependent route

    NARCIS (Netherlands)

    Luyer, Misha D.; Buurman, Wim A.; Hadfoune, M.'hamed; Wolfs, T.; van't Veer, Cornelis; Jacobs, Jan A.; Dejong, Cornelis H.; Greve, Jan Willem M.

    2007-01-01

    OBJECTIVE: To investigate the role of bacterial DNA in development of an excessive inflammatory response and loss of gut barrier loss following systemic hypotension. SUMMARY BACKGROUND DATA: Bacterial infection may contribute to development of inflammatory complications following major surgery;

  5. Ionization beam profile monitor for operation under hard environmental conditions

    International Nuclear Information System (INIS)

    Teterev, Yu.G.; Kaminski, G.; Phi Thanh Huong; Kaminski, G.; Kozik, E.

    2010-01-01

    The design and the performance of the Ionization Beam Profile Monitor (IBPM) operating on the residual gas ionization principle are described. The main advantage of the constructed device is the non-contact measuring method. Operating under hard environmental conditions it delivers the information about the primary beam position, profile and intensity in 'on-line' regime. It was found out that the device is capable to operate in vacuum in the range of 10 -6 /10 -3 mbar without the loss of the resolution power at the beam current as low as a few nA. The IBPM is prospective for beam profile monitoring due to long time. Emergency situations do not lead to decrease of its operability.

  6. Experimental investigation of energy loss and end loss physics in a linear theta pinch. Scientific report 81-3

    International Nuclear Information System (INIS)

    Jacoby, B.A.

    1981-01-01

    The results of an experimental study of particle and thermal loss processes from a 50-cm long theta pinch are presented. The plasma was generated with a 40-mTorr fill of deuterium in a 3.81 cm radius discharge tube; 67% Z-preionization was followed by a main current discharge that produced a 23-kG peak magnetic field in 4.75 μsec. The electron density and temperature in the plasma column at the end of dynamic implosion were characterized by 1.0 x 10 16 cm -3 and 20 eV, respectively. This was followed by adiabatic compression which occurred with the particle and energy loss of interest. The diagnostics employed in this experiment were Thomson scattering, continuum radiation spectroscopy, local magnetic-field probes, local pressure probes, and diamagnetic loops. Axial temperature and density profiles were mapped from the coil into the end region

  7. Hydrogeologic controls on saturation profiles in heat-pipe-like hydrothermal systems: numerical study

    Science.gov (United States)

    Pervin, Mollika; Ghergut, Iulia; Graf, Thomas; Peche, Aaron

    2016-04-01

    Most geothermal reservoirs are of the liquid-dominated type, and their unexploited-state pressure profile approximately follows the hydrostatic gradient. In very hot liquid-dominated systems, temperature typically follows a boiling-point-for-depth (BPD) relationship. By contrast, vapor-dominated systems exhibit (in their unexploited state) surprisingly small vertical gradients of temperature and pressure, such that a constantly high temperature is encountered over a large vertical thickness, while their pressure approximately follows vapour pressure, pvap(T°). This implies that (Pruess 1985, Truesdell and White 1973): (i) for a vapor-dominated reservoir to exist, it must be sealed laterally - otherwise it would be flooded by neighboring groundwaters with hydrostatic p profile, and (ii) liquid water should somehow be present in the whole system - otherwise p values would not be constrained by the pvap(T°) relationship for water. Historically, one of the most puzzling aspects of vapor-dominated systems was the large amount of heat flowing upwards, while vertical T° gradients remained negligible. This mechanism was deemed as 'heat pipe'(HP) (Eastman 1968): In the central zone of a vapor-dominated system, both vapor and liquid are mobile; vapor flows upwards, condenses at shallower depth, and the liquid condensate flows downwards. Due to the large amount of latent enthalpy released in vapor condensation, the vapor-liquid counter-flow can generate large rates of heat flow with negligible net mass transport (Pruess 1985). In order to be able to exploit two-phase (including vapor-dominated) reservoirs in a sustainable manner, one first needs to understand the conditions under which a two-phase (or a vapor-dominated) system has evolved naturally, and which have led to its present (quasi-) steady undisturbed state. Past studies have found that HP can exist in two distinct states, corresponding to liquid-dominated and vapor-dominated p profiles, respectively. Within this

  8. Beam profile monitors in the NLCTA

    International Nuclear Information System (INIS)

    Nantista, C.; Adolphsen, C.; Brown, R.L.; Fuller, R.; Rifkin, J.

    1997-05-01

    The transverse current profile in the Next Linear Collider Test Accelerator (NLCTA) electron beam can be monitored at several locations along the beam line by means of profile monitors. These consist of insertable phosphor screens, light collection and transport systems, CID cameras, a frame-grabber, and PC and VAX based image analysis software. In addition to their usefulness in tuning and steering the accelerator, the profile monitors are utilized for emittance measurement. A description of these systems and their performance is presented

  9. Cardiovascular risk-benefit profile of sibutramine.

    Science.gov (United States)

    Scheen, A J

    2010-01-01

    Sibutramine is a combined norepinephrine and serotonin reuptake inhibitor used as an antiobesity agent to reduce appetite and promote weight loss in combination with diet and exercise. At a daily dose of 10-20 mg, it was initially considered to have a good safety profile, as it does not induce primary pulmonary hypertension or adverse effects on cardiac valves, in contrast to previous reports relating to some other antiobesity agents. However, it exerts disparate effects on cardiovascular risk factors. On the one hand, sibutramine may have antiatherogenic activities, as it improves insulin resistance, glucose metabolism, dyslipidemia, and inflammatory markers, with most of these effects resulting from weight loss rather than from an intrinsic effect of the drug. On the other hand, because of its specific mode of action, sibutramine exerts a peripheral sympathomimetic effect, which induces a moderate increase in heart rate and attenuates the reduction in BP attributable to weight loss or even slightly increases BP. It may also prolong the QT interval, an effect that could induce arrhythmias. Because of these complex effects, it is difficult to conclude what the final impact of sibutramine on cardiovascular outcomes might be. Sibutramine has been shown to exert favorable effects on some surrogate cardiovascular endpoints such as reduction of left ventricular hypertrophy and improvement of endothelial dysfunction. A good cardiovascular safety profile was demonstrated in numerous 1- to 2-year controlled trials, in both diabetic and nondiabetic well selected patients, as well as in several observational studies. However, since 2002, several cardiovascular adverse events (hypertension, tachycardia, arrhythmias, and myocardial infarction) have been reported in sibutramine-treated patients. This led to a contraindication of the use of this antiobesity agent in patients with established coronary heart disease, previous stroke, heart failure, or cardiac arrhythmias. SCOUT

  10. Loss aversion in schizophrenia.

    Science.gov (United States)

    Trémeau, Fabien; Brady, Melissa; Saccente, Erica; Moreno, Alexis; Epstein, Henry; Citrome, Leslie; Malaspina, Dolores; Javitt, Daniel

    2008-08-01

    Loss aversion in decision-making refers to a higher sensitivity to losses than to gains. Loss aversion is conceived as an affective interference in cognitive processes such as judgment and decision-making. Loss aversion in non-risky choices has not been studied in schizophrenia. Forty-two individuals with schizophrenia and 42 non-patient control subjects, matched by gender and age, were randomized to two different scenarios (a buying scenario and a selling scenario). Subjects were asked to evaluate the price of a decorated mug. Schizophrenia subjects were re-tested four weeks later with the other scenario. Contrary to non-patient controls, schizophrenia subjects did not show loss aversion. In the schizophrenia group, absence of loss aversion was correlated with age, duration of illness, number of months in State hospitals, and poorer performance in the Wisconsin Card Sorting Test, but not with current psychopathology and two domains of emotional experience. Absence of loss aversion in schizophrenia represents a deficit in the processing of emotional information during decision-making. It can be interpreted as a lack of integration between the emotional and the cognitive systems, or to a more diffuse and de-differentiated impact of emotional information on decision-making. Future studies should bring more clarity to this question.

  11. Minimization of transmission loss using distributed generation approach

    Directory of Open Access Journals (Sweden)

    Lamin Chaantrea Miky

    2018-01-01

    Full Text Available The goal of this work is to calculate the total loss in the system and minimize this loss by implementation of distributed generation (DG technology. In this paper, load flow analysis method is followed to calculate the loss in the system in conjunction with the line flows. A simple 5 bus system with the main bus of the substation as the slack bus, three Plant generators at the generator bus and three load buses are taken for analysis. For loss minimization two distributed generators at two load buses are connected. One generator is a synchronous type model and the other is asynchronous type model. We searched for the most economical penetration level and the ratings of the distributed generators are decided by the magnitude of penetration power at each load bus. Using software, power system simulation for electrical (PSSE, the system with and without DG technology is modeled and the output from the PSSE is observed.

  12. Modelling of prompt losses of high energy charged particles in Tokamaks

    International Nuclear Information System (INIS)

    Dillner, Oe.; Anderson, D.; Hamnen, H.; Lisak, M.

    1990-01-01

    A simple analytical expression for the total prompt loss fraction of high energy charged particles in an axisymmetric Tokamak is derived. The results are compared with predictions obtained from numerical simulations and show good agreement. An application is made to sawtooth induced changes in the losses of fusion generated high energy charged particles. Particular emphasis is given to the importance of sawtooth induced profile changes of the background ion densities and temperature as well as to redistribution of particles which have accumulated during the sawtooth rise but are being lost by redistribution at the sawtooth crash. (au)

  13. Stratifying patients with peripheral neuropathic pain based on sensory profiles

    DEFF Research Database (Denmark)

    Vollert, Jan; Maier, Christoph; Attal, Nadine

    2017-01-01

    In a recent cluster analysis, it has been shown that patients with peripheral neuropathic pain can be grouped into 3 sensory phenotypes based on quantitative sensory testing profiles, which are mainly characterized by either sensory loss, intact sensory function and mild thermal hyperalgesia and...... populations that need to be screened to reach a subpopulation large enough to conduct a phenotype-stratified study. The most common phenotype in diabetic polyneuropathy was sensory loss (83%), followed by mechanical hyperalgesia (75%) and thermal hyperalgesia (34%, note that percentages are overlapping...

  14. School Health Profiles 2014: West Virginia Rankings

    Science.gov (United States)

    West Virginia Department of Education Office of Research, Accountability, and Data Governance, 2015

    2015-01-01

    The School Health Profiles (Profiles) is a system of surveys assessing school health policies and practices in states, large urban school districts, and territories. Profiles surveys are conducted biennially by education and health agencies among middle and high school principals and lead health education teachers. Profiles monitors the current…

  15. Assessment of System Behavior and Actions Under Loss of Electric Power For CANDU

    Energy Technology Data Exchange (ETDEWEB)

    Kang, San Ha; Moon, Bok Ja; Kim, Seoung Rae [Nuclear Engineering Service and Solution Co., Ltd., Daejeon (Korea, Republic of)

    2014-05-15

    For the analysis, the CANDU-6 plant in Korea is considered and only the passive components are operable. The other systems are assumed to be at failed condition due to the loss of electric power. At this accident, only the inventories remained in the primary heat transport system (PHTS) and steam generator can be used for the decay heat removal. Due to the transfer of decay heat, the inventory of steam generator secondary side is discharged to the air through passive operation of main steam safety valves (MSSVs). After the steam generators are dried, the PHTS is over-pressurized and the coolant is discharged to fuelling machine vault through passive operation of degasser condenser tank relief valves (DCRVs). Under this situation, the maintenance of the integrity of PHTS is important for the protection of radionuclides release to the environment. Thus, deterministic analysis using CATHENA code is carried out for the simulation of the accident and the appropriate operator action is considered. The loss of electric power results in the depletion of steam generator inventory which is necessary for the decay heat removal. If only the passive system is credited, the PT can be failed after the steam generator is depleted. For the prevention of the PT failure, the feedwater should be supplied to the steam generator before 4,800s after the accident. The feedwater can be supplied using water in dousing tank if the steam generators are depressurized. The decay heat from the core is removed through natural circulation if the feedwater can be supplied continuously.

  16. Association between raf kinase inhibitor protein loss and prognosis in cancers of the digestive system: a meta-analysis.

    Science.gov (United States)

    Yu, Min; Wang, Qian; Ding, Jiang-Wu; Yang, Zhen; Xie, Chuan; Lu, Nong-Hua

    2014-01-01

    Loss of Raf kinase inhibitor protein (RKIP) may contribute to metastasis in a variety of human cancers. Many studies have evaluated whether loss of RKIP expression is a prognostic factor for survival in cancers of the digestive system, however, its predictive value remains controversial. Thus, we performed a meta-analysis to obtain a more comprehensive estimate of the prognostic value of RKIP expression in digestive system cancers. Studies were identified by searching multiple electronic databases through December 12, 2013, and by reviewing reference lists of obtained articles. Studies reported hazard ratios (HRs) with 95% confidence intervals (CIs) for the association between RKIP and overall survival (OS) and disease-free survival (DFS) in cancers of the digestive system were eligible, including esophageal cancer, gastric cancer, colorectal cancer and pancreatic cancer. Nineteen studies involving approximately 3700 participants were included in the final analysis. The pooled results suggested that loss of RKIP expression was associated with unfavorable OS (HR 0.55, 95% CI 0.46-0.65) and DFS (HR 0.46, 95% CI 0.30-0.62) among patients with digestive system cancers, whereas the difference was not statistically significant in pancreatic cancer specifically (OS, HR 0.76; 95% CI 0.51-1.01; DFS, HR 0.71; 95% CI 0.28-1.13). Loss of RKIP expression might be an independent indicator of poor prognosis in patients with digestive tract cancers, which includes esophageal cancer, gastric cancer and colorectal cancer. More studies are needed to further clarify the prognostic value of RKIP in pancreatic cancer. Future studies, preferably large prospective studies utilizing formal marker assessment processes, are needed to establish the prognostic value of RKIP before these results can be clinically applied.

  17. Loss Minimizing Operation of Doubly Fed Induction Generator Based Wind Generation Systems Considering Reactive Power Provision

    DEFF Research Database (Denmark)

    Baohua, Zhang; Hu, Weihao; Chen, Zhe

    2014-01-01

    The paper deals with control techniques for minimizing the operating loss of doubly fed induction generator based wind generation systems when providing reactive power. The proposed method achieves its goal through controlling the rotor side q-axis current in the synchronous reference frame...

  18. Fluorine concentration profiles in archaeological bone

    International Nuclear Information System (INIS)

    Coote, G.E.; Sparks, R.J.

    1981-01-01

    The nuclear microprobe at the Institute of Nuclear Sciences was applied to the measurement of radial concentration profiles of fluorine, in transverse slices of archaeological bone from humans, moas, and other animals. A beam of 2.5 MeV protons was focused to a rectangular spot 250 microns by 50 microns, traversed along a radial line 3mm long, and gamma rays of 5-7 MeV from the reaction 19 F(p, α#betta#) 16 O were detected in a large sodium iodide crystal. Bombardment caused no detectable loss of fluorine from the bone. Measured profiles display a wide variety of shapes and maximum concentrations. In bones which had been exposed to ground water the fluorine concentration usually increases from the centre towards the surface, sometimes by as much as a factor of eight. The concentration at the surface is usually in the range 0.2 to 1%, though in moa bone from a limestone cave it is only 0.025%. Once a quantitative method of analysis has been developed, based on the shape of the profile rather than its magnitude, these profiles might be useful for dating bone. In the meantime, they could be used to distinguish bones of different ages from a common site

  19. Loss of Landau Damping for Inductive Impedance in a Double RF System

    CERN Document Server

    Argyropoulos, T; Burov, A

    2013-01-01

    In this paper the thresholds of the loss of Landau damping due to the presence of inductive impedance in a single and double harmonic RF systems are determined, both from calculations and particle simulations. A high harmonic RF system, operating in bunch lengthening mode is used in many accelerators with space charge or inductive impedance to reduce the peak line density or stabilize the beam. An analytical approach, based on emerging of the discrete Van Kampen modes, shows that improved stability in a double RF system can be achieved only below some critical value of longitudinal emittance. Above this threshold, a phase shift of more than 15 degrees between the two RF components is proven necessary to stabilize the bunch. These results, confirmed also by particle simulations, now are able to explain observations during the pp operation of the SPS. The thresholds in bunch shortening mode as well as in a single RF case are compared with this regime.

  20. End loss analyzer system for measurements of plasma flux at the C-2U divertor electrode

    Energy Technology Data Exchange (ETDEWEB)

    Griswold, M. E., E-mail: mgriswold@trialphaenergy.com; Korepanov, S.; Thompson, M. C. [Tri Alpha Energy, P.O. Box 7010, Rancho Santa Margarita, California 92688 (United States)

    2016-11-15

    An end loss analyzer system consisting of electrostatic, gridded retarding-potential analyzers and pyroelectric crystal bolometers was developed to characterize the plasma loss along open field lines to the divertors of C-2U. The system measures the current and energy distribution of escaping ions as well as the total power flux to enable calculation of the energy lost per escaping electron/ion pair. Special care was taken in the construction of the analyzer elements so that they can be directly mounted to the divertor electrode. An attenuation plate at the entrance to the gridded retarding-potential analyzer reduces plasma density by a factor of 60 to prevent space charge limitations inside the device, without sacrificing its angular acceptance of ions. In addition, all of the electronics for the measurement are isolated from ground so that they can float to the bias potential of the electrode, 2 kV below ground.

  1. The EVOTION Decision Support System: Utilizing It for Public Health Policy-Making in Hearing Loss.

    Science.gov (United States)

    Katrakazas, Panagiotis; Trenkova, Lyubov; Milas, Josip; Brdaric, Dario; Koutsouris, Dimitris

    2017-01-01

    As Decision Support Systems start to play a significant role in decision making, especially in the field of public-health policy making, we present an initial attempt to formulate such a system in the concept of public health policy making for hearing loss related problems. Justification for the system's conceptual architecture and its key functionalities are presented. The introduction of the EVOTION DSS sets a key innovation and a basis for paradigm shift in policymaking, by incorporating relevant models, big data analytics and generic demographic data. Expected outcomes for this joint effort are discussed from a public-health point of view.

  2. Integration of polystyrene microlenses with both convex and concave profiles in a polymer-based microfluidic system

    KAUST Repository

    Fan, Yiqiang; Li, Huawei; Foulds, Ian G.

    2013-01-01

    This paper reports a new technique of fabricating polystyrene microlenses with both convex and concave profiles that are integrated in polymer-based microfluidic system. The polystyrene microlenses, or microlens array, are fabricated using the free

  3. Reducing nitrate loss in tile drainage water with cover crops and water-table management systems.

    Science.gov (United States)

    Drury, C F; Tan, C S; Welacky, T W; Reynolds, W D; Zhang, T Q; Oloya, T O; McLaughlin, N B; Gaynor, J D

    2014-03-01

    Nitrate lost from agricultural soils is an economic cost to producers, an environmental concern when it enters rivers and lakes, and a health risk when it enters wells and aquifers used for drinking water. Planting a winter wheat cover crop (CC) and/or use of controlled tile drainage-subirrigation (CDS) may reduce losses of nitrate (NO) relative to no cover crop (NCC) and/or traditional unrestricted tile drainage (UTD). A 6-yr (1999-2005) corn-soybean study was conducted to determine the effectiveness of CC+CDS, CC+UTD, NCC+CDS, and NCC+UTD treatments for reducing NO loss. Flow volume and NO concentration in surface runoff and tile drainage were measured continuously, and CC reduced the 5-yr flow-weighted mean (FWM) NO concentration in tile drainage water by 21 to 38% and cumulative NO loss by 14 to 16% relative to NCC. Controlled tile drainage-subirrigation reduced FWM NO concentration by 15 to 33% and cumulative NO loss by 38 to 39% relative to UTD. When CC and CDS were combined, 5-yr cumulative FWM NO concentrations and loss in tile drainage were decreased by 47% (from 9.45 to 4.99 mg N L and from 102 to 53.6 kg N ha) relative to NCC+UTD. The reductions in runoff and concomitant increases in tile drainage under CC occurred primarily because of increases in near-surface soil hydraulic conductivity. Cover crops increased corn grain yields by 4 to 7% in 2004 increased 3-yr average soybean yields by 8 to 15%, whereas CDS did not affect corn or soybean yields over the 6 yr. The combined use of a cover crop and water-table management system was highly effective for reducing NO loss from cool, humid agricultural soils. Copyright © by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America, Inc.

  4. Use efficiency of nitrogen fertilizers in wheat and losses of nitrogen in the crop system

    International Nuclear Information System (INIS)

    Barbaro, Nestor O.; Lopez, Silvia C.; Melaj, Mariana; Martin, O; Rojas de Tramontini, Susana

    1999-01-01

    Full text: The sustenance of crop production systems is related to the maintenance of soil fertility. The nutrients taken up by the crops must be restored to the soil and nutrient loss should be minimized. In order to study the dynamics of nitrogen in a wheat production system, some studies using isotopic tracers were begun. These studies were supported by IAEA (ARCAL XXII and IAEA ARG 5/008 projects). The field experiences were carried out in four different locations within Buenos Aires, in Balcarce, Barrow, Bordenave and Pergamino. Each one consisted of two treatments (fertilized and non fertilized) and four replicates for each. 15 N-labelled urea was applied to micro plots, within the fertilized plots, at sowing and the unlabelled fertilizer was broadcast over the rest of the plot. Application of N fertilization increased grain yields by 1600, 1500, 500 and 150 kg/ha in Balcarce, Barrow, Bordenave and Pergamino respectively. The low increase obtained in Pergamino can be related to climatic conditions. In this case, the yield was lower than the potential average due to high rain level and low solar radiation. The recovery in plants of 15 N-labelled fertilizer was high, between 36,5% and 43%, except for Pergamino where only 16% of the labelled urea was recovered. Since samples were taken at different growing stages, some data on nitrogen losses from the crop are available. It is very important to continue the measurement of these losses

  5. Cannabis and Δ9-tetrahydrocannabinol (THC) for weight loss?

    Science.gov (United States)

    Le Foll, Bernard; Trigo, Jose M; Sharkey, Keith A; Le Strat, Yann

    2013-05-01

    Obesity is one of the highest preventable causes of morbidity and mortality in the developed world [1]. It has been well known for a long time that exposure to cannabis produces an increase of appetite (a phenomenon referred to as the 'munchies'). This phenomenon led to an exploration of the role of the endocannabinoid system in the regulation of obesity and associated metabolic syndrome. This effort subsequently led to the development of a successful therapeutic approach for obesity that consisted of blocking the cannabinoid CB1 receptors using ligands such as Rimonabant in order to produce weight loss and improve metabolic profile [2]. Despite being efficacious, Rimonabant was associated with increased rates of depression and anxiety and therefore removed from the market. We recently discovered that the prevalence of obesity is paradoxically much lower in cannabis users as compared to non-users and that this difference is not accounted for by tobacco smoking status and is still present after adjusting for variables such as sex and age. Here, we propose that this effect is directly related to exposure to the Δ(9)-tetrahydrocannabinol (THC) present in cannabis smoke. We therefore propose the seemingly paradoxical hypothesis that THC or a THC/cannabidiol combination drug may produce weight loss and may be a useful therapeutic for the treatment of obesity and its complications. Copyright © 2013 Elsevier Ltd. All rights reserved.

  6. Time pulse profiles on a new data acquisition system for neutron time of flight diffractometer

    International Nuclear Information System (INIS)

    Venegas, R.; Baeza, L.; Navarro, G.

    1999-01-01

    A new differential acquisition system was built for a neutron diffuse scattering instrument. We analyze the time, space and velocity behavior of neutron pulse profiles, which can be obtained in a neutron diffuse scattering system of this nature, consisting of a black disc slit chopper and a circular detector bank, in order to design accurate scattering data analyzing methods. Computed direct pulse time spectra and measured spectra show satisfactory agreement. (author)

  7. Reduction of solids and nutrient loss from agricultural land by tailwater recovery systems

    Science.gov (United States)

    Omer, A.R.; Miranda, Leandro E.; Moore, M. T.; Krutz, L. J.; Prince Czarnecki, J. M.; Kröger, R.; Baker, B. H.; Hogue, J.; Allen, P. J.

    2018-01-01

    Best management practices are being implemented throughout the Lower Mississippi River Alluvial Valley with the aim of alleviating pressures placed on downstream aquatic systems by sediment and nutrient losses from agricultural land; however, research evaluating the performance of tailwater recovery (TWR) systems, an increasingly important practice, is limited. This study evaluated the ability of TWR systems to retain sediment and nutrients draining from agricultural landscapes. Composite flow-based samples were collected during flow events (precipitation or irrigation) over a two-year period in six TWR systems. Performance was evaluated by comparing concentrations and loads in water entering TWR systems (i.e., runoff or influent) from agricultural fields to water overflow exiting TWR systems (effluent). Tailwater recovery systems did not reduce concentrations of solids and nutrients, but did reduce loads of solids, phosphorus (P), and nitrogen (N) by 43%, 32%, and 44%, respectively. Annual mean load reductions were 1,142 kg solids, 0.7 kg of P, and 3.8 kg of N. Performance of TWR systems was influenced by effluent volume, system fullness, time since the previous event, and capacity of the TWR system. Mechanistically, TWR systems retain runoff on the agricultural landscape, thereby reducing the amount of sediment and nutrients entering downstream waterbodies. System performance can be improved through manipulation of influential parameters.

  8. Environmental Nitrogen Losses from Commercial Crop Production Systems in the Suwannee River Basin of Florida.

    Science.gov (United States)

    Prasad, Rishi; Hochmuth, George J

    2016-01-01

    The springs and the Suwannee river of northern Florida in Middle Suwanee River Basin (MSRB) are among several examples in this planet that have shown a temporal trend of increasing nitrate concentration primarily due to the impacts of non-point sources such as agriculture. The rate of nitrate increase in the river as documented by Ham and Hatzell (1996) was 0.02 mg N L-1 y-1. Best management practices (BMPs) for nutrients were adopted by the commercial farms in the MSRB region to reduce the amounts of pollutants entering the water bodies, however the effectiveness of BMPs remains a topic of interest and discussion among the researchers, environmental administrators and policy makers about the loads of nitrogen entering into groundwater and river systems. Through this study, an initiative was taken to estimate nitrogen losses into the environment from commercial production systems of row and vegetable crops that had adopted BMPs and were under a presumption of compliance with state water quality standards. Nitrogen mass budget was constructed by quantifying the N sources and sinks for three crops (potato (Solanum tuberosum L.), sweet corn (Zea mays L.) and silage corn (Zea mays L.)) over a four year period (2010-2013) on a large representative commercial farm in northern Florida. Fertilizer N was found to be the primary N input and represented 98.0 ± 1.4, 91.0 ± 13.9, 78.0 ± 17.3% of the total N input for potato, sweet corn, and silage corn, respectively. Average crop N uptake represented 55.5%, 60.5%, and 65.2% of the mean total input N whereas average mineral N left in top 0.3 m soil layer at harvest represented 9.1%, 4.5%, and 2.6% of the mean total input N. Mean environmental N losses represented 35.3%, 34.3%, and 32.7% of the mean total input N for potato, sweet corn, and silage corn, respectively. Nitrogen losses showed a linear trend with increase in N inputs. Although, there is no quick fix for controlling N losses from crop production in MSRB, the

  9. New, Coupling Loss Induced, Quench Protection System for Superconducting Accelerator Magnets

    CERN Document Server

    Ravaioli, E; Giloux, C; Kirby, G; ten Kate, H H J; Verweij, A P

    2014-01-01

    Email Print Request Permissions Save to Project A new and promising method for the protection of superconducting high-field magnets is developed and tested on the so-called MQXC quadrupole magnet at the CERN magnet test facility. The method relies on a capacitive discharge system inducing, during a few periods, an oscillation of the transport current in the superconducting cable of the coil. The corresponding fast change of the local magnetic field introduces a high coupling-current loss, which, in turn, causes a fast quench of a large fraction of the coil due to enhanced temperature. Results of measured discharges at various levels of transport current are presented and compared to discharges by quenching the coils using conventional quench heaters and an energy extraction system. The hot-spot temperature in the quenching coil is deduced from the coil voltage and current. The results are compared to simulations carried out using a lumped-element dynamic electro-thermal model of the so-called MQX...

  10. ELECTRODYNAMICS OF TRANSMISSION AND LOSSES OF POWER IN THE DEVICES OF ELECTRIC TRACTION SYSTEMS

    Directory of Open Access Journals (Sweden)

    M. O. Kostin

    2014-01-01

    Full Text Available Purpose. Theoretical justification of the "field" approach (based on electromagnetic field to the transmission and losses of power in the devices of traction power supply systems and electric rolling stock. Methodology. The methods of electromagnetic field theory and, in particular, the theory and practice of electromagnetic energy transmission based on the concept of the Poynting vector and elements of the theory of propagation, reflection and refraction of plane electromagnetic waves were used. Findings. Theoretical studies of electromagnetic energy transmission from the traction substation to the electric rolling stock through dielectric (air surrounding traction network: between the contact wire and the rail were carried out. It is proposed strategic designing "squat" (low types of electric rolling stock. The components of electric energy flow through the roof of electric rolling stock and its frontal part of the body were estimated. This allows reliable etimating active power losses in electric traction system. To compensate the reactive power consumed by electric rolling stock, which is conditioned by standing waves, it is proposed (for extinction of the the last to develop and put in front of electric rolling stock the layer of particular environment with the necessary parameters. Originality. The "field" principle of the power transmission analysis and its losses arising in electric traction system was first proposed. The laws of motion of electromagnetic energy flows through the roof and the frontal part of the body of electric rolling stock were established. Practical value. An expression of the absolute value of the Poynting vector in the points of dielectric (air between the contact wire and the rail was obtained. This allows assessing the highest density of energy, which is transferred to the time unit and predicting the main dimensions of the unit of electric rolling stock. The energy indices of the roof of electric rolling stock

  11. Systemic Inflammatory Response to Malaria During Pregnancy Is Associated With Pregnancy Loss and Preterm Delivery.

    Science.gov (United States)

    Fried, Michal; Kurtis, Jonathan D; Swihart, Bruce; Pond-Tor, Sunthorn; Barry, Amadou; Sidibe, Youssoufa; Gaoussou, Santara; Traore, Moussa; Keita, Sekouba; Mahamar, Almahamoudou; Attaher, Oumar; Dembele, Adama B; Cisse, Kadidia B; Diarra, Bacary S; Kanoute, Moussa B; Dicko, Alassane; Duffy, Patrick E

    2017-10-30

    Pregnancy malaria (PM) is associated with a proinflammatory immune response characterized by increased levels of cytokines and chemokines such as tumor necrosis factor-α, interferon-γ, interleukin 10 (IL-10), and CXCL9. These changes are associated with poor outcomes including low birthweight delivery and maternal anemia. However, it is unknown if inflammatory pathways during malaria are related to pregnancy loss and preterm delivery (PTD). Cytokine and chemokine levels were measured in maternal peripheral blood at enrollment, gestational week 30-32, and delivery, and in placental blood, of 638 women during a longitudinal cohort study in Ouelessebougou, Mali. Plasmodium falciparum infection was assessed by blood smear microscopy at all visits. PM was associated with increased levels of cytokines and chemokines including IL-10 and CXCL9. In a competing risks model adjusted for known covariates, high CXCL9 levels measured in the peripheral blood during pregnancy were associated with increased risk of pregnancy loss and PTD. At delivery, high IL-10 levels in maternal blood were associated with an increase in pregnancy loss, and increased IL-1β levels in placental blood were associated with pregnancy loss and PTD. PM is associated with increased proinflammatory cytokine and chemokine levels in placental and maternal peripheral blood. Systemic inflammatory responses to malaria during pregnancy predict increased risk of pregnancy loss and PTD. NCT01168271. Published by Oxford University Press for the Infectious Diseases Society of America 2017. This work is written by (a) US Government employee(s) and is in the public domain in the US.

  12. Landslides in Colorado, USA--Impacts and loss estimation for 2010

    Science.gov (United States)

    Highland, Lynn M.

    2012-01-01

    The focus of this study is to investigate landslides and consequent losses which affected Colorado in the year 2010. By obtaining landslide reports from a variety of sources, this report will demonstrate the feasibility of creating a profile of landslides and their effects on communities. A short overview of the current status of landslide-loss studies for the United States is introduced, followed by a compilation of landslide occurrence and associated losses and impacts which affected Colorado for the year 2010. Direct costs are summarized in descriptive and tabular form, and where possible, indirect costs are also noted or estimated. Total direct costs of landslides in Colorado for the year 2010 were approximately $9,149,335.00 (2010 U.S. dollars). (Since not all data for damages and costs were obtained, this figure realistically could be considerably higher.) Indirect costs were noted where available but are not totaled due to the fact that most indirect costs were not obtainable for various reasons outlined later in this report. Casualty data are considered as being within the scope of loss evaluation, and are reported in Appendix 1, but are not assigned dollar losses. More details on the source material for loss data not found in the reference section are reported in Appendix 2, and Appendix 3 summarizes notes on landslide-loss investigations in general and lessons learned during the process of loss-data collection.

  13. 48 CFR 32.1010 - Risk of loss.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Risk of loss. 32.1010... REQUIREMENTS CONTRACT FINANCING Performance-Based Payments 32.1010 Risk of loss. (a) Under the clause at 52.232... loss occurs in connection with property for which the contractor bears the risk, and the property is...

  14. Evaluation of the Vestibular System and Etiology in Children with Unilateral Sensorineural Hearing Loss.

    Science.gov (United States)

    Birdane, Leman; İncesulu, Armağan; Özüdoğru, Erkan; Cingi, Cemal; Caklı, Hamdi; Gürbüz, Melek Kezban; Adapınar, Baki

    2016-08-01

    The aim of this study was to evaluate the vestibular system of children with unilateral sensorineural hearing loss (USNHL), investigate the etiological factors of USNHL and analyze whether a genetic predisposition exists. Thirty-three children aged less than 18 years with USNHL, who visited the ear, nose, and throat (ENT) department between January 2004 and December 2012, were included in this study. Cases with conductive hearing loss were excluded from the study. The patients were subjected to etiologic, genetic, and ophthalmologic evaluation; radiologic imaging; electronystagmography (ENG); and vestibular evoked myogenic potential (VEMP) tests. The control group, which included 25 healthy children (13 males and 12 females), had undergone audiological assessment and were subjected to ENG and VEMP tests. All of the patients had severe-to-profound hearing loss. Mumps immunoglobulin G was positive in 22 (66.7%) of 33 patients. The 35delG mutation was not found in any of the patients. All of the patients underwent temporal computed tomography (CT) and magnetic resonance imaging (MRI). Inner ear anomaly was present in 51.5% of the patients. Overall, 21 of 31 ENG patients had canal paresis in the affected ear. The VEMP response was absent on the affected side in three patients. The n23 latency average of the patient group was longer than that of the control group. Because USNHL causes irreversible problems in children, early diagnosis and auditory rehabilitation are very important. As USNHL is accompanied by inner ear anomaly, children with USNHL should undergo temporal bone CT and MRI. To evaluate the vestibular system, ENG and VEMP are non-invasive and diagnostic tests.

  15. Measurement system of bubbly flow using ultrasonic velocity profile monitor and video data processing unit. 2. Flow characteristics of bubbly countercurrent flow

    International Nuclear Information System (INIS)

    Aritomi, Masanori; Zhou, Shirong; Nakajima, Makoto; Takeda, Yasushi; Mori, Michitsugu.

    1997-01-01

    The authors have developed a measurement system which is composed of an ultrasonic velocity profile monitor and a video data processing unit in order to clarify its multi-dimensional flow characteristics in bubbly flows and to offer a data base to validate numerical codes for multi-dimensional two-phase flow. In this paper, the measurement system was applied for bubbly countercurrent flows in a vertical rectangular channel. At first, both bubble and water velocity profiles and void fraction profiles in the channel were investigated statistically. Next, turbulence intensity in a continuous liquid phase was defined as a standard deviation of velocity fluctuation, and the two-phase multiplier profile of turbulence intensity in the channel was clarified as a ratio of the standard deviation of flow fluctuation in a bubbly countercurrent flow to that in a water single phase flow. Finally, the distribution parameter and drift velocity used in the drift flux model for bubbly countercurrent flows were calculated from the obtained velocity profiles of both phases and void fraction profile, and were compared with the correlation proposed for bubbly countercurrent flows. (author)

  16. A Profiling System for the Assessment of Individual Needs for Rehabilitation With Hearing Aids

    Directory of Open Access Journals (Sweden)

    Wouter A. Dreschler

    2016-10-01

    Full Text Available This study focuses on the development of a profiling system to specify the needs of hearing-aid candidates. As a basis for the profile of compensation needs, we used a slightly modified version of the Amsterdam Inventory of Disability and Handicap, combined with the well-known Client-Oriented Scale of Improvement (COSI. The first questionnaire results in scores for six audiological dimensions: detection, speech in quiet, speech in noise, localization, focus or discrimination, and noise tolerance. The goal of this study was to determine whether the six dimensions derived from the disability questionnaire are appropriate to also categorize individual COSI targets. The results show a good agreement between eight audiologists in the categorization of COSI goals along the six dimensions. The results per dimension show that the dimension focus or discrimination can be regarded as superfluous. Possible additional dimensions were tinnitus and listening effort. The results indicate that it is possible to translate individual user needs (administered using COSI into more general dimensions derived from a disability questionnaire. This allows to summarize the compensation needs for individual patients in a profile of general dimensions, based on the degree of disability and the individual user needs. This profile can be used as a starting point in hearing aid selection. This approach also offers a well-structured method for the evaluation of the postfitting results.

  17. Influence of a variable Rayleigh scattering-loss coefficient on the light backscattering in multimode optical fibers.

    Science.gov (United States)

    Bisyarin, M A; Kotov, O I; Hartog, A H; Liokumovich, L B; Ushakov, N A

    2017-06-01

    The recently developed diffraction technique of analytical investigation of the Rayleigh backscattering produced by an incident fundamental mode in a multimode optical fiber with an arbitrary refractive index profile is supplemented by taking into account the Rayleigh scattering-loss coefficient, which could be variable within the fiber cross section. The relative changes in various radial and azimuthal modes' excitation levels, due to some typical radial dependences of this coefficient, are computed for the quadratic- and step-index fibers. It is stated that the excitation efficiency could either rise or decay for different modes. The effect of the variable Rayleigh scattering-loss coefficient is shown to be more noticeable in the fibers with a quadratic refractive index profile, whereas it is negligible in actual multimode step-index fibers.

  18. Controlled release profiles of dipyridamole from biodegradable microspheres on the base of poly(3-hydroxybutyrate.

    Directory of Open Access Journals (Sweden)

    2007-12-01

    Full Text Available Novel biodegradable microspheres on the base of poly(3-hydroxybutyrate (PHB designed for controlled release of antithrombotic drug, namely dipyridamole (DPD, have been kinetically studied. The profiles of release from the microspheres with different diameters 4, 9, 63, and 92 µm present the progression of nonlinear and linear stages. Diffusionkinetic equation describing both linear (PHB hydrolysis and nonlinear (diffusion stages of the DPD release profiles from the spherical subjects has been written down as the sum of two terms: desorption from the homogeneous sphere in accordance with diffusion mechanism and the zero-order release. In contrast to the diffusivity dependence on microsphere size, the constant characteristics (k of linearity are scarcely affected by the diameter of PHB microparticles. The view of the kinetic profiles as well as the low rate of DPD release are in satisfactory agreement with kinetics of weight loss measured in vitro for the PHB films. Taking into account kinetic results, we suppose that the degradation of both films and PHB microspheres is responsible for the linear stage of DPD release profiles. In the nearest future, combination of biodegradable PHB and DPD as a representative of proliferation cell inhibitors will give possibility to elaborate the novel injectable therapeutic system for a local, long-term, antiproliferative action.

  19. Feasability study of using the TFTR Thomson scattering system for q profile measurements

    International Nuclear Information System (INIS)

    Brizard, A.; Grewk, B.; Johnson, D.; LeBlanc, B.

    1986-01-01

    The results of a study made to determine the possibility of using the TFTR 76 channels Thomson scattering system to measure the direction of local magnetic fields in a tokamak plasma are presented. As this is a local measurement, this technique can in principle yield q profiles without the need of any de-convolution. The effect of the TFTR geometrical configuration and its various components on the expected measurement accuracy is discussed. The authors find that the measurement of q values within the inner half of the plasma should be possible, with only minor modification to the present TVTS system

  20. Improving the profile of the European tourist destinations through the European tourism indicators system

    Directory of Open Access Journals (Sweden)

    Laura CISMARU

    2015-06-01

    Full Text Available Within the most recent European Policy for Tourism, the competitiveness of the European tourism industry is directly linked to the image of Europe and to its perception, as a collection of sustainable and high-quality tourist destinations. In such context, improving the profile of the European tourist destinations has become a main target. During the last years, the European Commission focused on the sustainable development of tourist destinations. Several projects were developed, the most recent one introducing a practical tool - the European Tourism Indicators System (ETIS for the sustainable development of destinations. The present paper advances the idea that such tool can be successfully used in order to achieve the goal of improving the profile of the European tourist destinations.

  1. Cryogenic Beam Loss Monitoring for the LHC

    CERN Document Server

    Kurfuerst, C; Sapinski, M

    A Beam Loss Monitoring (BLM) system was installed on the outside surface of the LHC magnet cryostats to protect the accelerator equipment from beam losses. The protection is achieved by extracting the beam from the ring in case thresholds imposed on measured radiation levels are exceeded. Close to the interaction regions of the LHC, the present BLM system is sensitive to particle showers generated in the interaction region of the two beams. In the future, with beams of higher energy and brightness resulting in higher luminosity, distinguishing between these interaction products and possible quench-provoking beam losses from the primary proton beams will be challenging. The particle showers measured by the present BLM configuration are partly shielded by the cryostat and the iron yoke of the magnets. The system can hence be optimised by locating beam loss monitors as close as possible to the protected element, i. e. the superconducting coils, inside the cold mass of the magnets in superfluid helium at 1.9 K. T...

  2. Patient profiling for success after weight loss surgery (GO Bypass study)

    DEFF Research Database (Denmark)

    Christensen, Bodil Just; Schmidt, Julie Berg; Nielsen, Mette Søndergaard

    2018-01-01

    Despite substantial research efforts, the mechanisms proposed to explain weight loss after gastric bypass (RYGB) and sleeve gastrectomy (SL) do not explain the large individual variation seen after these treatments. A complex set of factors are involved in the onset and development of obesity...... and these may also be relevant for the understanding of why success with treatments vary considerably between individuals. This calls for explanatory models that take into account not only biological determinants but also behavioral, affective and contextual factors. In this prospective study, we recruited 47...... and include: physiological measures: anthropometrics, vital signs, biochemical measures and appetite hormones, genetics, gut microbiota, appetite sensation, food and taste preferences, neural sensitivity, sensory perception and movement behaviors; psychological measures: general psychiatric symptom...

  3. Age-Associated Loss of OPA1 in Muscle Impacts Muscle Mass, Metabolic Homeostasis, Systemic Inflammation, and Epithelial Senescence.

    Science.gov (United States)

    Tezze, Caterina; Romanello, Vanina; Desbats, Maria Andrea; Fadini, Gian Paolo; Albiero, Mattia; Favaro, Giulia; Ciciliot, Stefano; Soriano, Maria Eugenia; Morbidoni, Valeria; Cerqua, Cristina; Loefler, Stefan; Kern, Helmut; Franceschi, Claudio; Salvioli, Stefano; Conte, Maria; Blaauw, Bert; Zampieri, Sandra; Salviati, Leonardo; Scorrano, Luca; Sandri, Marco

    2017-06-06

    Mitochondrial dysfunction occurs during aging, but its impact on tissue senescence is unknown. Here, we find that sedentary but not active humans display an age-related decline in the mitochondrial protein, optic atrophy 1 (OPA1), that is associated with muscle loss. In adult mice, acute, muscle-specific deletion of Opa1 induces a precocious senescence phenotype and premature death. Conditional and inducible Opa1 deletion alters mitochondrial morphology and function but not DNA content. Mechanistically, the ablation of Opa1 leads to ER stress, which signals via the unfolded protein response (UPR) and FoxOs, inducing a catabolic program of muscle loss and systemic aging. Pharmacological inhibition of ER stress or muscle-specific deletion of FGF21 compensates for the loss of Opa1, restoring a normal metabolic state and preventing muscle atrophy and premature death. Thus, mitochondrial dysfunction in the muscle can trigger a cascade of signaling initiated at the ER that systemically affects general metabolism and aging. Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.

  4. Structure-related bulk losses in ZrO sub 2 optical thin films

    Energy Technology Data Exchange (ETDEWEB)

    Duparre, A; Welsch, E; Walther, H G [Sektion Physik, Friedrich-Schiller-Univ. Jena (German Democratic Republic); Kaiser, N; Mueller, H [Physikalisch-Technisches Inst. der Akademie der Wissenschaften der DDR, Jena (German Democratic Republic); Hacker, E; Lauth, H; Meyer, J; Weissbrodt, P [Kombinat VEB Carl Zeiss, Jena (German Democratic Republic)

    1990-06-01

    Results of measurements of bulk scattering as well as absorption losses of evaporated ZrO{sub 2} single-layer films are presented. A special layer design was used to eliminate the losses originating from the film interfaces. The scattering and absorption measurements are performed at {lambda}=515 nm by means of total integrated scattering and photoacoustic techniques, respectively. Transmission electron micrographs of C-Pt replicas of cross-sections and electron diffraction studies reveal the correlations between bulk losses and morphology. The compositional depth profiles of the films were investigated by secondary neutral mass spectrometry. The observed absorption can be explained by contaminations homogeneously distributed throughout the film thicknss. The results are discussed with respect to different deposition conditions and post-deposition annealing. (orig.).

  5. [Hearing loss and idoneity--the segnalation of noise-induced hearing loss hearing Loss].

    Science.gov (United States)

    Albera, Roberto; Dagna, Federico; Cassandro, Claudia; Canale, Andrea

    2011-01-01

    Work idoneity in hearing loss must be related to working ability and evolution risks. Working ability is referred to the difficulties found in speech comprehension and in signals perception. As regards hearing loss evolution it is necessary to define if the subject is affected by conductive or neurosensorial hearing loss. In conductive hearing loss it is necessary to evaluate entity and frequential distribution of the deficit. In neurosensorial hearing loss it is necessary to distinguish between noise-induced hearing loss and extraprofessional hearing loss. In noise-induced hearing loss the evolution risk is high if the noise exposure is less than 10-15 years or the actual noise exposure is louder than the former. In case of extraprofessional hearing loss the evolution risk is higher in presbycusis, endolymphatic hydrops and toxic hearing loss. The necessity to report the presence on professionale noise-induced hearing loss arises if audiometric threshold is more than 25 dB at 0.5-1-2-3-4 kHz and if it is verified the professional origine of hearing loss.

  6. Exploring personalized searches using tag-based user profiles and resource profiles in folksonomy.

    Science.gov (United States)

    Cai, Yi; Li, Qing; Xie, Haoran; Min, Huaqin

    2014-10-01

    With the increase in resource-sharing websites such as YouTube and Flickr, many shared resources have arisen on the Web. Personalized searches have become more important and challenging since users demand higher retrieval quality. To achieve this goal, personalized searches need to take users' personalized profiles and information needs into consideration. Collaborative tagging (also known as folksonomy) systems allow users to annotate resources with their own tags, which provides a simple but powerful way for organizing, retrieving and sharing different types of social resources. In this article, we examine the limitations of previous tag-based personalized searches. To handle these limitations, we propose a new method to model user profiles and resource profiles in collaborative tagging systems. We use a normalized term frequency to indicate the preference degree of a user on a tag. A novel search method using such profiles of users and resources is proposed to facilitate the desired personalization in resource searches. In our framework, instead of the keyword matching or similarity measurement used in previous works, the relevance measurement between a resource and a user query (termed the query relevance) is treated as a fuzzy satisfaction problem of a user's query requirements. We implement a prototype system called the Folksonomy-based Multimedia Retrieval System (FMRS). Experiments using the FMRS data set and the MovieLens data set show that our proposed method outperforms baseline methods. Copyright © 2014 Elsevier Ltd. All rights reserved.

  7. Economic losses and burden of disease by medical conditions in Norway.

    Science.gov (United States)

    Kinge, Jonas Minet; Sælensminde, Kjartan; Dieleman, Joseph; Vollset, Stein Emil; Norheim, Ole Frithjof

    2017-06-01

    We explore the correlation between disease specific estimates of economic losses and the burden of disease. This is based on data for Norway in 2013 from the Global Burden of Disease (GBD) project and the Norwegian Directorate of Health. The diagnostic categories were equivalent to the ICD-10 chapters. Mental disorders topped the list of the costliest conditions in Norway in 2013, and musculoskeletal disorders caused the highest production loss, while neoplasms caused the greatest burden in terms of DALYs. There was a positive and significant association between economic losses and burden of disease. Neoplasms, circulatory diseases, mental and musculoskeletal disorders all contributed to large health care expenditures. Non-fatal conditions with a high prevalence in working populations, like musculoskeletal and mental disorders, caused the largest production loss, while fatal conditions such as neoplasms and circulatory disease did not, since they occur mostly at old age. The magnitude of the production loss varied with the estimation method. The estimations presented in this study did not include reductions in future consumption, by net-recipients, due to premature deaths. Non-fatal diseases are thus even more burdensome, relative to fatal diseases, than the production loss in this study suggests. Hence, ignoring production losses may underestimate the economic losses from chronic diseases in countries with an epidemiological profile similar to Norway. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Hot spot model of MagLIF implosions: Nernst term effect on magnetic flux losses

    Science.gov (United States)

    Garcia Rubio, Fernando; Sanz Recio, Javier; Betti, Riccardo

    2016-10-01

    An analytical model of a collisional plasma being compressed by a cylindrical liner is proposed and solved in a magnetized liner inertial fusion-like context. The implosion is assumed to be isobaric, and the magnetic diffusion is confined to a thin layer near the liner. Both unmagnetized and magnetized plasma cases are considered. The model reduces to a system of two partial differential equations for temperature and magnetic field. Special attention is given to the effect of the Nernst term on the evolution of the magnetic field. Scaling laws for temperature, magnetic field, hot spot mass increase and magnetic field losses are obtained. The temperature and magnetic field spatial profiles tend to a self-similar state. It is found that when the Nernst term is taken into account, the magnetic field is advected towards the liner, and the magnetic flux losses are independent of the magnetic Lewis number. Research supported by the Spanish Ministerio de Economía y Competitividad, Project No. ENE2014-54960R. Acknowledgements to the Laboratory of Laser Energetics (Rochester) for its hospitality.

  9. ADT fast losses MD

    CERN Document Server

    Priebe, A; Dehning, B; Redaelli, S; Salvachua Ferrando, BM; Sapinski, M; Solfaroli Camillocci, M; Valuch, D

    2013-01-01

    The fast beam losses in the order of 1 ms are expected to be a potential major luminosity limitation for higher beam energies after the LHC long shutdown (LS1). Therefore a Quench Test is planned in the winter 2013 to estimate the quench limit in this timescale and revise the current models. This experiment was devoted to determination the LHC Transverse Damper (ADT) as a system for fast losses induction. A non-standard operation of the ADT was used to develop the beam oscillation instead of suppressing them. The sign flip method had allowed us to create the fast losses within several LHC turns at 450 GeV during the previous test (26th March 2012). Thus, the ADT could be potentially used for the studies of the UFO ("Unidentied Falling Object") impact on the cold magnets. Verification of the system capability and investigations of the disturbed beam properties were the main objectives of this MD. During the experiment, the pilot bunches of proton beam were excited independently in the horizontal and vertical ...

  10. Vertical grid of retrieved atmospheric profiles

    International Nuclear Information System (INIS)

    Ceccherini, Simone; Carli, Bruno; Raspollini, Piera

    2016-01-01

    The choice of the vertical grid of atmospheric profiles retrieved from remote sensing observations is discussed considering the two cases of profiles used to represent the results of individual measurements and of profiles used for subsequent data fusion applications. An ozone measurement of the MIPAS instrument is used to assess, for different vertical grids, the quality of the retrieved profiles in terms of profile values, retrieval errors, vertical resolutions and number of degrees of freedom. In the case of individual retrievals no evident advantage is obtained with the use of a grid finer than the one with a reduced number of grid points, which are optimized according to the information content of the observations. Nevertheless, this instrument dependent vertical grid, which seems to extract all the available information, provides very poor results when used for data fusion applications. A loss of about a quarter of the degrees of freedom is observed when the data fusion is made using the instrument dependent vertical grid relative to the data fusion made using a vertical grid optimized for the data fusion product. This result is explained by the analysis of the eigenvalues of the Fisher information matrix and leads to the conclusion that different vertical grids must be adopted when data fusion is the expected application. - Highlights: • Data fusion application is taken into account for the choice of the vertical grid. • The study is performed using ozone profiles retrieved from MIPAS measurements. • A very fine vertical grid is not needed for the analysis of a single instrument. • The instrument dependent vertical grid is not the best choice for data fusion. • A data fusion dependent vertical grid must be used for profiles that will be fused.

  11. Knowledge Loss: Managing Local Knowledge in Rural Uzbekistan

    OpenAIRE

    Wall, Caleb; Evers, Hans-Dieter

    2006-01-01

    Knowledge loss is not a remote phenomenon, unique to one knowledge system. Rather we argue that the loss of knowledge is an issue for other knowledge systems as well. Knowledge loss is certainly a concern for anthropologists working on indigenous knowledge, fearful of ‘losing’ indigenous knowledge entirely as a result of modernisation (cf. Cox, 2000). Equally, staff movements within the corporate world probably lead to a large amount of knowledge displacement, yet staff (and thus knowledge) r...

  12. Dependence of direct losses and trapping properties with the magnetic configuration in TJ-II

    International Nuclear Information System (INIS)

    Guasp, J.; Liniers, M.

    1998-05-01

    The former studies concerning direct losses, disymmetries, trapping and radial electric field effects for intermediate energy ions have been extended to several magnetic configurations in TJ-II. In the absence of electric field there are strong similarities in the behaviour of all configurations: disymmetries, loss distributions at plasma border, radial and angular profiles, etc. Generally the differences are only quantitative and dominated by the magnetic ripple at border, that is clearly related with the configuration radius. This qualitative similarity disappears in the presence of a radial electric field. The field resonance are at the origin of these differences. A simple model reproduces correctly the ordering and degree of influence of these resonances. Except when the 0 resonance predominates the los distributions at plasma border move always in the direction of the induced poloidal rotation. The los radial profiles are strongly affected by the -2 Resonance, that can provoke the appearance of lost passing ions well inside the plasma. Instead the radial and angular profiles for trapping are only slightly affected by the -2 Resonance, while the 0 Resonance has a very strong influence there

  13. Applied research of Primary Pump Mission Profile construction

    International Nuclear Information System (INIS)

    Zheng, Gang-yang; Zhang, Zhi-jian; Ye, Quan-liu; Du, Zhi-hao; Ma, Ying-fei; Zhang, Hua-zhi

    2017-01-01

    Highlights: • Minimum Associated Subtask (MAS) and Minimum Effective Component (MEC) are presented in Mission Profile analysis. • Via applying MAS and MEC, Mission Profile plays a more important role in complex system reliability analysis. • Mission Profile has already been used in the reliability analysis of localized Chinese 1000 MW NPP Primary Pump. - Abstract: The traditional Mission Profile analysis did not clarify the accurate concept of minimum subtask and component. However, there are several components, which could be the influencing key element of the system reliability; and there are several subtasks, which could be used as a basic and crucial mission. In this paper, traditional method of Mission Profile has been extended by incorporating two new ideas: Minimum Associated Subtask (MAS) and Minimum Effective Component (MEC). This method of Mission Profile modeling is derived from Chinese 1000 MW NPP Primary Pump localization. A case study on Primary Pump reliability has been presented; then, MAS and MEC have been existed as vital elements in its lifecycle profile construction. By means of MAS and MEC, Mission Profile plays a more important role on complex system (Primary Pump) reliability analysis.

  14. Towards a slow extraction system for the TRIUMF KAON Factory extender ring with 0.1% losses

    International Nuclear Information System (INIS)

    Wienands, U.; Servranckx, R.V.

    1988-06-01

    In order to reduce extraction losses a modified third-integral slow extraction system is proposed using a 0.5 m long and 10 μm thin electrostatic pre-septum. Various factors limiting the extraction efficiency like power-supply noise and synchrotron oscillations are investigated analytically as well as by simulation, and the losses are estimated to be as low as 0.2%. The extracted beam emittance is about 0.2 π mm-mrad. For chromatic extraction a reduction in momentum width of the extracted beam by a factor of 2.5, resulting in an extracted momentum bite of less than 30 MeV/c FWHM, can be achieved without emittance blowup. The duty factor typically is between 55% and 65%. Between 1.8% and 3.7% of the particles did not get extracted by the resonant system. First investigation of half-integer extraction indicates possible difficulties in achieving small extracted emittances. (Author) (5 refs., 4 figs.)

  15. A model on CME/Flare initiation: Loss of Equilibrium caused by mass loss of quiescent prominences

    Science.gov (United States)

    Miley, George; Chon Nam, Sok; Kim, Mun Song; Kim, Jik Su

    2015-08-01

    Coronal Mass Ejections (CMEs) model should give an answer to enough energy storage for giant bulk plasma into interplanetary space to escape against the sun’s gravitation and its explosive eruption. Advocates of ‘Mass Loading’ model (e.g. Low, B. 1996, SP, 167, 217) suggested a simple mechanism of CME initiation, the loss of mass from a prominence anchoring magnetic flux rope, but they did not associate the mass loss with the loss of equilibrium. The catastrophic loss of equilibrium model is considered as to be a prospective CME/Flare model to explain sudden eruption of magnetic flux systems. Isenberg, P. A., et al (1993, ApJ, 417, 368)developed ideal magnetohydrodynamic theory of the magnetic flux rope to show occurrence of catastrophic loss of equilibrium according to increasing magnetic flux transported into corona.We begin with extending their study including gravity on prominence’s material to obtain equilibrium curves in case of given mass parameters, which are the strengths of the gravitational force compared with the characteristic magnetic force. Furthermore, we study quasi-static evolution of the system including massive prominence flux rope and current sheet below it to obtain equilibrium curves of prominence’s height according to decreasing mass parameter in a properly fixed magnetic environment. The curves show equilibrium loss behaviors to imply that mass loss result in equilibrium loss. Released fractions of magnetic energy are greater than corresponding zero-mass case. This eruption mechanism is expected to be able to apply to the eruptions of quiescent prominences, which is located in relatively weak magnetic environment with 105 km of scale length and 10G of photospheric magnetic field.

  16. BEND-INDUCED LOSSES IN A SINGLE-MODE MICROSTRUCTURED FIBER WITH A LARGE CORE

    Directory of Open Access Journals (Sweden)

    Y. A. Gatchin

    2015-03-01

    Full Text Available A study of bend-induced losses in a silica-based single-mode microstructured fiber with a core diameter ranging from 20 to 35 microns and increased relative air content in the holey cladding has been conducted. With the use of the equivalent step-index profile method in approximation of waveguide parameters of microstructured fiber (normalized frequency and normalized transverse attenuation constant the effect of bending on the spectral position of the fundamentalmode short-wavelength leakage boundary has been analyzed. Upon measurement of spectral characteristics of attenuation in the considered fibers good accordance of numerical and experimental data has been found out. It is shown that increase of the air content in the holey cladding leads to expansion of the mentioned boundary to lower wavelengths for the value from 150 to 800 nm depending on the core size and bending conditions. A single-transverse-mode propagation is achieved on fiber length of 5-10 meters due to a substantial difference in losses of fundamental and higher-order guided modes attained by bending. Optical losses in all studied samples are less than 10 dB/km at the wavelength λ = 1550 nm. The results of the study can be applied in the design of high-power laser systems having such basic requirements as a relatively large mode spot and high beam quality.

  17. THREE-PHASE ENERGY SUPPLY SYSTEMS SIMULATION FOR THE TOTAL POWER LOSSES COMPONENTS ASSESSMENT

    Directory of Open Access Journals (Sweden)

    D.V. Tugay

    2016-09-01

    Full Text Available Purpose. The goal is to optimize a structure of Matlab-model of the three-phase energy supply system with power active filter. The mathematical model that describes the energy supply system modes of operation which contains additional losses is proposed. Methodology. We have applied concepts of the electrical circuits theory, mathematical modeling elements based on linear algebra and vector calculus, mathematical simulation in Matlab package. Results. We have developed two models of three-phase energy supply system. The first one is based on a vector representation, and the second one on the matrix representation of energy processes. Using these models we have solved the problem of maintaining unchanged the average useful power for 279 cases of energy supply system modes of operation. Originality. We have developed methods of mathematical analysis of a three-phase energy supply systems with polyharmonic voltages and currents in the symmetric and asymmetric modes. Practical value. We have created Matlab-model of a three-phase energy supply system with automated calculation of a correction factor. It allows reducing more than one order the time for energy processes elucidation in multiphase systems.

  18. A study on the development of automatic economic profit and loss calculation system for maritime boundary delimitation

    International Nuclear Information System (INIS)

    Kwak, G; Kim, K; Park, Y

    2014-01-01

    As the maritime boundary delimitation is important for the purpose of securing marine resources, in addition to the aspect of maritime security, interest in maritime boundary delimitation to help national benefits are increasing over the world. In Korea, the importance of maritime boundary delimitation with the neighbouring countries is also increasing in practice. The quantity of obtainable marine resources depending on maritime boundary acts as an important factor for maritime boundary delimitation. Accordingly, a study is required to calculate quantity of our obtainable marine resources depending on maritime boundary delimitation. This study intends to calculate obtainable marine resources depending on various maritime boundary scenarios insisted by several countries. It mainly aims at developing a GIS-based automation system to be utilized for decision making of the maritime boundary delimitation. For this target, it has designed a module using spatial analysis technique to automatically calculate profit and loss waters area of each country upon maritime boundary and another module to estimate economic profits and losses obtained by each country using the calculated waters area and pricing information of the marine resources. By linking both the designed modules, it has implemented an automatic economic profit and loss calculation system for the GIS-based maritime boundary delimitation. The system developed from this study automatically calculate quantity of the obtainable marine resources of a country for the maritime boundary to be added and created in the future. Thus, it is expected to support decision making for the maritime boundary negotiators

  19. A study on the development of automatic economic profit and loss calculation system for maritime boundary delimitation

    Science.gov (United States)

    Kwak, G.; Kim, K.; Park, Y.

    2014-02-01

    As the maritime boundary delimitation is important for the purpose of securing marine resources, in addition to the aspect of maritime security, interest in maritime boundary delimitation to help national benefits are increasing over the world. In Korea, the importance of maritime boundary delimitation with the neighbouring countries is also increasing in practice. The quantity of obtainable marine resources depending on maritime boundary acts as an important factor for maritime boundary delimitation. Accordingly, a study is required to calculate quantity of our obtainable marine resources depending on maritime boundary delimitation. This study intends to calculate obtainable marine resources depending on various maritime boundary scenarios insisted by several countries. It mainly aims at developing a GIS-based automation system to be utilized for decision making of the maritime boundary delimitation. For this target, it has designed a module using spatial analysis technique to automatically calculate profit and loss waters area of each country upon maritime boundary and another module to estimate economic profits and losses obtained by each country using the calculated waters area and pricing information of the marine resources. By linking both the designed modules, it has implemented an automatic economic profit and loss calculation system for the GIS-based maritime boundary delimitation. The system developed from this study automatically calculate quantity of the obtainable marine resources of a country for the maritime boundary to be added and created in the future. Thus, it is expected to support decision making for the maritime boundary negotiators.

  20. Estimation on the Pressure Loss of the Conceptual Primary Cooling System and Design of the Primary Cooling Pump for a Research Reactor

    International Nuclear Information System (INIS)

    Seo, Kyoung Woo; Oh, Jae Min; Park, Jong Hark; Chae, Hee Taek; Seo, Jae Kwang; Park, Cheon Tae; Yoon, Ju Hyeon; Lee, Doo Jeong

    2009-01-01

    A new conceptual primary cooling system (PCS) for a research reactor has been designed for an adequate cooling to the reactor core which has various powers ranging from 30MW through 80MW. The developed primary cooling system consisted of decay tanks, pumps, heat exchangers, vacuum breakers, some isolation and check valves, connection piping, and instruments. Because the system flow rate should be determined by the thermal hydraulic design analysis for the core, the heads to design the primary cooling pumps (PCPs) in a PCS will be estimated by the variable system flow rates. The heads of the part of a research reactor vessel was evaluated by the previous study. The various pressure losses of the PCS can be calculated by the dimensional analysis of the pipe flow and the head loss coefficient of the components. The purpose of this research is to estimate the various pressure losses and to design the PCPs