SNP calling using genotype model selection on high-throughput sequencing data

KAUST Repository

You, Na

2012-01-16

Motivation: A review of the available single nucleotide polymorphism (SNP) calling procedures for Illumina high-throughput sequencing (HTS) platform data reveals that most rely mainly on base-calling and mapping qualities as sources of error when calling SNPs. Thus, errors not involved in base-calling or alignment, such as those in genomic sample preparation, are not accounted for.Results: A novel method of consensus and SNP calling, Genotype Model Selection (GeMS), is given which accounts for the errors that occur during the preparation of the genomic sample. Simulations and real data analyses indicate that GeMS has the best performance balance of sensitivity and positive predictive value among the tested SNP callers. © The Author 2012. Published by Oxford University Press. All rights reserved.

The job demands-resources model of work engagement in South African call centres

Directory of Open Access Journals (Sweden)

Yolandi Janse van Rensburg

2013-09-01

Full Text Available Orientation: A ‘sacrificial human resource strategy’ is practised in call centres, resulting in poor employee occupational health. Consequently, questions are posed in terms of the consequences of call centre work and which salient antecedent variables impact the engagement and wellbeing of call centre representatives. Research purpose: Firstly, to gauge the level of employee engagement amongst a sample of call centre representatives in South Africa and, secondly, to track the paths through which salient personal and job resources affect this engagement. More specifically, the relationships between sense of coherence, leadership effectiveness, team effectiveness and engagement were investigated, thus testing the Job Demands-Resources model of work engagement. Motivation for the study: To present an application of the Job Demands-Resources model of work engagement in a call centre environment in order to diagnose current ills and consequently propose remedies. Research design: A cross-sectional survey design was used and a non-probability convenient sample of 217 call centre representatives was selected. The measuring instruments comprise the Utrecht Work Engagement Scale to measure engagement, the Team Diagnostic Survey to measure team effectiveness, the leadership practices inventory to gauge leadership effectiveness, and the Orientation to Life Questionnaire to measure sense of coherence. A series of structural equation modelling analyses were performed. Main findings: Contrary to the ‘electronic sweatshop’ image attached to call centre jobs depicted in the literature, results show a high level of employee engagement for call centre representatives in the sample. Also, personal resources such as sense of coherence and job resources such as team effectiveness related significantly to engagement. A non-significant relationship exists between leadership effectiveness and engagement. Practical/managerial implications: Both the content and

The job demands-resources model of work engagement in South African call centres

Directory of Open Access Journals (Sweden)

Yolandi Janse van Rensburg

2013-09-01

Full Text Available Orientation: A ‘sacrificial human resource strategy’ is practised in call centres, resulting in poor employee occupational health. Consequently, questions are posed in terms of the consequences of call centre work and which salient antecedent variables impact the engagement and wellbeing of call centre representatives.Research purpose: Firstly, to gauge the level of employee engagement amongst a sample of call centre representatives in South Africa and, secondly, to track the paths through which salient personal and job resources affect this engagement. More specifically, the relationships between sense of coherence, leadership effectiveness, team effectiveness and engagement were investigated, thus testing the Job Demands-Resources model of work engagement.Motivation for the study: To present an application of the Job Demands-Resources model of work engagement in a call centre environment in order to diagnose current ills and consequently propose remedies.Research design: A cross-sectional survey design was used and a non-probability convenient sample of 217 call centre representatives was selected. The measuring instruments comprise the Utrecht Work Engagement Scale to measure engagement, the Team Diagnostic Survey to measure team effectiveness, the leadership practices inventory to gauge leadership effectiveness, and the Orientation to Life Questionnaire to measure sense of coherence. A series of structural equation modelling analyses were performed.Main findings: Contrary to the ‘electronic sweatshop’ image attached to call centre jobs depicted in the literature, results show a high level of employee engagement for call centre representatives in the sample. Also, personal resources such as sense of coherence and job resources such as team effectiveness related significantly to engagement. A non-significant relationship exists between leadership effectiveness and engagement.Practical/managerial implications: Both the content and

Personal summarization from profile networks

Institute of Scientific and Technical Information of China (English)

Zhongqing WANG; Shoushan LI; Guodong ZHOU

2017-01-01

Personal profile information on social media like Linkedln.com and Facebook.com is at the core of many interesting applications,such as talent recommendation and contextual advertising.However,personal profiles usually lack consistent organization confronted with the large amount of available information.Therefore,it is always a challenge for people to quickly find desired information from them.In this paper,we address the task of personal profile summarization by leveraging both textual information and social connection information in social networks from both unsupervised and supervised learning paradigms.Here,using social connection information is motivated by the intuition that people with similar academic,business or social background (e.g.,comajor,co-university,and co-corporation) tend to have similar experiences and should have similar summaries.For unsupervised learning,we propose a collective ranking approach,called SocialRank,to combine textual information in an individual profile and social context information from relevant profiles in generating a personal profile summary.For supervised learning,we propose a collective factor graph model,called CoFG,to summarize personal profiles with local textual attribute functions and social connection factors.Extensive evaluation on a large dataset from LinkedIn.com demonstrates the usefulness of social connection information in personal profile summarization and the effectiveness of our proposed unsupervised and supervised learning approaches.

Modeling shoreface profile evolution

NARCIS (Netherlands)

Stive, M.J.F.; De Vriend, H.J.

1995-01-01

Current knowledge of hydro-, sediment and morpho-dynamics in the shoreface environment is insufficient to undertake shoreface-profile evolution modelling on the basis of first physical principles. We propose a simple, panel-type model to map observed behaviour. The internal dynamics are determined

Modelling shoreface profile evolution

NARCIS (Netherlands)

Stive, Marcel J.F.; de Vriend, Huib J.

1995-01-01

Current knowledge of hydro-, sediment and morpho-dynamics in the shoreface environment is insufficient to undertake shoreface-profile evolution modelling on the basis of first physical principles. We propose a simple, panel-type model to map observed behaviour. The internal dynamics are determined

Modeling of Changing Electrode Profiles

Energy Technology Data Exchange (ETDEWEB)

Prentice, Geoffrey Allen [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Materials and Molecular Research Division; Univ. of California, Berkeley, CA (United States). Dept. of Chemical Engineering

1980-12-01

A model for simulating the transient behavior of solid electrodes undergoing deposition or dissolution has been developed. The model accounts for ohmic drop, charge transfer overpotential, and mass transport limitations. The finite difference method, coupled with successive overrelaxation, was used as the basis of the solution technique. An algorithm was devised to overcome the computational instabilities associated with the calculations of the secondary and tertiary current distributions. Simulations were performed on several model electrode profiles: the sinusoid, the rounded corner, and the notch. Quantitative copper deposition data were obtained in a contoured rotating cylinder system, Sinusoidal cross-sections, machined on stainless steel cylinders, were used as model geometries, Kinetic parameters for use in the simulation were determined from polarization curves obtained on copper rotating cylinders, These parameters, along with other physical property and geometric data, were incorporated in simulations of growing sinusoidal profiles. The copper distributions on the sinusoidal cross-sections were measured and found to compare favorably with the simulated results. At low Wagner numbers the formation of a slight depression at the profile peak was predicted by the simulation and observed on the profile. At higher Wagner numbers, the simulated and experimental results showed that the formation of a depression was suppressed. This phenomenon was shown to result from the competition between ohmic drop and electrode curvature.

Perceiving a Calling, Living a Calling, and Job Satisfaction: Testing a Moderated, Multiple Mediator Model

Science.gov (United States)

Duffy, Ryan D.; Bott, Elizabeth M.; Allan, Blake A.; Torrey, Carrie L.; Dik, Bryan J.

2012-01-01

The current study examined the relation between perceiving a calling, living a calling, and job satisfaction among a diverse group of employed adults who completed an online survey (N = 201). Perceiving a calling and living a calling were positively correlated with career commitment, work meaning, and job satisfaction. Living a calling moderated…

A Step-indexed Semantic Model of Types for the Call-by-Name Lambda Calculus

OpenAIRE

Meurer, Benedikt

2011-01-01

Step-indexed semantic models of types were proposed as an alternative to purely syntactic safety proofs using subject-reduction. Building upon the work by Appel and others, we introduce a generalized step-indexed model for the call-by-name lambda calculus. We also show how to prove type safety of general recursion in our call-by-name model.

Towards Agent-Oriented Approach to a Call Management System

Science.gov (United States)

Ashamalla, Amir Nabil; Beydoun, Ghassan; Low, Graham

There is more chance of a completed sale if the end customers and relationship managers are suitably matched. This in turn can reduce the number of calls made by a call centre reducing operational costs such as working time and phone bills. This chapter is part of ongoing research aimed at helping a CMC to make better use of its personnel and equipment while maximizing the value of the service it offers to its client companies and end customers. This is accomplished by ensuring the optimal use of resources with appropriate real-time scheduling and load balancing and matching the end customers to appropriate relationship managers. In a globalized market, this may mean taking into account the cultural environment of the customer, as well as the appropriate profile and/or skill of the relationship manager to communicate effectively with the end customer. The chapter evaluates the suitability of a MAS to a call management system and illustrates the requirement analysis phase using i* models.

Insights into N-calls of mitochondrial DNA sequencing using MitoChip v2.0

Directory of Open Access Journals (Sweden)

Blakely Emma L

2011-10-01

Full Text Available Abstract Background Developments in DNA resequencing microarrays include mitochondrial DNA (mtDNA sequencing and mutation detection. Failure by the microarray to identify a base, compared to the reference sequence, is designated an 'N-call.' This study re-examined the N-call distribution of mtDNA samples sequenced by the Affymetrix MitoChip v.2.0, based on the hypothesis that N-calls may represent insertions or deletions (indels in mtDNA. Findings We analysed 16 patient mtDNA samples using MitoChip. N-calls by the proprietary GSEQ software were significantly reduced when either of the freeware on-line algorithms ResqMi or sPROFILER was utilized. With sPROFILER, this decrease in N-calls had no effect on the homoplasmic or heteroplasmic mutation levels compared to GSEQ software, but ResqMi produced a significant change in mutation load, as well as producing longer N-cell stretches. For these reasons, further analysis using ResqMi was not attempted. Conventional DNA sequencing of the longer N-calls stretches from sPROFILER revealed 7 insertions and 12 point mutations. Moreover, analysis of single-base N-calls of one mtDNA sample found 3 other point mutations. Conclusions Our study is the first to analyse N-calls produced from GSEQ software for the MitoChipv2.0. By narrowing the focus to longer stretches of N-calls revealed by sPROFILER, conventional sequencing was able to identify unique insertions and point mutations. Shorter N-calls also harboured point mutations, but the absence of deletions among N-calls suggests that probe confirmation affects binding and thus N-calling. This study supports the contention that the GSEQ is more capable of assigning bases when used in conjunction with sPROFILER.

Queueing System with Heterogeneous Customers as a Model of a Call Center with a Call-Back for Lost Customers

OpenAIRE

Dudin, Sergey; Kim, Chesoong; Dudina, Olga; Baek, Janghyun

2013-01-01

A multiserver queueing system with infinite and finite buffers, two types of customers, and two types of servers as a model of a call center with a call-back for lost customers is investigated. Type 1 customers arrive to the system according to a Markovian arrival process. All rejected type 1 customers become type 2 customers. Type r, r=1,2, servers serve type r customers if there are any in the system and serve type r′, r′=1,2,  r′≠r, customers if there are no type r customers in the system....

Architecture oriented modeling and simulation method for combat mission profile

Directory of Open Access Journals (Sweden)

CHEN Xia

2017-05-01

Full Text Available In order to effectively analyze the system behavior and system performance of combat mission profile, an architecture-oriented modeling and simulation method is proposed. Starting from the architecture modeling,this paper describes the mission profile based on the definition from National Military Standard of China and the US Department of Defense Architecture Framework(DoDAFmodel, and constructs the architecture model of the mission profile. Then the transformation relationship between the architecture model and the agent simulation model is proposed to form the mission profile executable model. At last,taking the air-defense mission profile as an example,the agent simulation model is established based on the architecture model,and the input and output relations of the simulation model are analyzed. It provides method guidance for the combat mission profile design.

Portable and Accurate Collection of Calling-Context-Sensitive Bytecode Metrics for the Java Virtual Machine

DEFF Research Database (Denmark)

Sarimbekov, Aibek; Sewe, Andreas; Binder, Walter

2011-01-01

Calling-context profiles and dynamic metrics at the bytecode level are important for profiling, workload characterization, program comprehension, and reverse engineering. Prevailing tools for collecting calling-context profiles or dynamic bytecode metrics often provide only incomplete information...... that compute various dynamic bytecode metrics from the profiles. As a case-study and tutorial on the use of JP2, we use it for crossprofiling for an embedded Java processor....

Biomimetic agent based modelling using male Frog calling behaviour as a case study

DEFF Research Database (Denmark)

Jørgensen, Søren V.; Demazeau, Yves; Christensen-Dalsgaard, Jakob

2014-01-01

by individuals to generate their observed population behaviour. A number of existing agent-modelling frameworks are considered, but none have the ability to handle large numbers of time-dependent event-generating agents; hence the construction of a new tool, RANA. The calling behaviour of the Puerto Rican Tree...... Frog, E. coqui, is implemented as a case study for the presentation and discussion of the tool, and results from this model are presented. RANA, in its present stage of development, is shown to be able to handle the problem of modelling calling frogs, and several fruitful extensions are proposed...

Model-based quality assessment and base-calling for second-generation sequencing data.

Science.gov (United States)

Bravo, Héctor Corrada; Irizarry, Rafael A

2010-09-01

Second-generation sequencing (sec-gen) technology can sequence millions of short fragments of DNA in parallel, making it capable of assembling complex genomes for a small fraction of the price and time of previous technologies. In fact, a recently formed international consortium, the 1000 Genomes Project, plans to fully sequence the genomes of approximately 1200 people. The prospect of comparative analysis at the sequence level of a large number of samples across multiple populations may be achieved within the next five years. These data present unprecedented challenges in statistical analysis. For instance, analysis operates on millions of short nucleotide sequences, or reads-strings of A,C,G, or T's, between 30 and 100 characters long-which are the result of complex processing of noisy continuous fluorescence intensity measurements known as base-calling. The complexity of the base-calling discretization process results in reads of widely varying quality within and across sequence samples. This variation in processing quality results in infrequent but systematic errors that we have found to mislead downstream analysis of the discretized sequence read data. For instance, a central goal of the 1000 Genomes Project is to quantify across-sample variation at the single nucleotide level. At this resolution, small error rates in sequencing prove significant, especially for rare variants. Sec-gen sequencing is a relatively new technology for which potential biases and sources of obscuring variation are not yet fully understood. Therefore, modeling and quantifying the uncertainty inherent in the generation of sequence reads is of utmost importance. In this article, we present a simple model to capture uncertainty arising in the base-calling procedure of the Illumina/Solexa GA platform. Model parameters have a straightforward interpretation in terms of the chemistry of base-calling allowing for informative and easily interpretable metrics that capture the variability in

Informed consent to address trust, control, and privacy concerns in user profiling.

NARCIS (Netherlands)

van der Geest, Thea; Pieterson, Willem Jan; de Vries, Pieter Walter

2005-01-01

More and more, services and products are being personalised or tailored, based on user-related data stored in so called user profiles or user models. Although user profiling offers great benefits for both organisations and users, there are several psychological factors hindering the potential

A machine learning model to determine the accuracy of variant calls in capture-based next generation sequencing.

Science.gov (United States)

van den Akker, Jeroen; Mishne, Gilad; Zimmer, Anjali D; Zhou, Alicia Y

2018-04-17

Next generation sequencing (NGS) has become a common technology for clinical genetic tests. The quality of NGS calls varies widely and is influenced by features like reference sequence characteristics, read depth, and mapping accuracy. With recent advances in NGS technology and software tools, the majority of variants called using NGS alone are in fact accurate and reliable. However, a small subset of difficult-to-call variants that still do require orthogonal confirmation exist. For this reason, many clinical laboratories confirm NGS results using orthogonal technologies such as Sanger sequencing. Here, we report the development of a deterministic machine-learning-based model to differentiate between these two types of variant calls: those that do not require confirmation using an orthogonal technology (high confidence), and those that require additional quality testing (low confidence). This approach allows reliable NGS-based calling in a clinical setting by identifying the few important variant calls that require orthogonal confirmation. We developed and tested the model using a set of 7179 variants identified by a targeted NGS panel and re-tested by Sanger sequencing. The model incorporated several signals of sequence characteristics and call quality to determine if a variant was identified at high or low confidence. The model was tuned to eliminate false positives, defined as variants that were called by NGS but not confirmed by Sanger sequencing. The model achieved very high accuracy: 99.4% (95% confidence interval: +/- 0.03%). It categorized 92.2% (6622/7179) of the variants as high confidence, and 100% of these were confirmed to be present by Sanger sequencing. Among the variants that were categorized as low confidence, defined as NGS calls of low quality that are likely to be artifacts, 92.1% (513/557) were found to be not present by Sanger sequencing. This work shows that NGS data contains sufficient characteristics for a machine-learning-based model to

PEMBUATAN MODEL PROFIL MAHASISWA FAKULTAS TEKNIK UNIVERSITAS PANCASILA

Directory of Open Access Journals (Sweden)

Paryudi Paryudi

2009-01-01

Full Text Available Promotion is a must for a university to get students. With the innocence of the promotion team about the existing student profile, it will cause the team does not know which segment should be the promotion target. The consequence is that the promotion cost will be higher. In order to have a better promotion, we can use direct marketing method. In this method, a profile model of the existing students must be first created. With this profile model, promotion team can focus the promotion only to candidate student match with the model. The advantages of this method are: promotion cost can be reduced, response rate increase, and profit also increase. In order to create a model in direct marketing, we need previous promotion data. Since previous promotion data is not available, two methods in creating preliminary models are proposed. Next, the preliminary models will be tested using data mining software available in the market. Model with minimal accuracy of 75% will be chosen. If there are more than one model with minimal accuracy of 75%, then model with the highest accuracy will be chosen. Abstract in Bahasa Indonesia: Promosi merupakan suatu keharusan bagi sebuah universitas untuk mendapatkan mahasiswa. Dengan masih awamnya tim promosi terhadap profil mahasiswa yang sudah ada, maka tim promosi melakukan promosi tanpa melihat segmen pasar yang harus dituju. Konsekuensinya adalah biaya promosi menjadi lebih mahal. Untuk melakukan promosi dengan lebih baik, dapat menggunakan metode direct marketing. Pada metode ini, model profil dari mahasiswa yang sudah ada harus dibuat terlebih dulu. Dengan menggunakan model profil ini, tim promosi dapat memfokuskan promosi hanya pada calon-calon mahasiswa yang sesuai dengan model. Keuntungan dari metode promosi ini adalah biaya promosi dapat dikurangi, tingkat respon meningkat, dan keuntungan juga meningkat. Untuk membuat model pada direct marketing dibutuhkan data dari promosi sebelumnya. Karena data promosi

Steven MacCall: Winner of LJ's 2010 Teaching Award

Science.gov (United States)

Berry, John N., III

2010-01-01

This article profiles Steven L. MacCall, winner of "Library Journal's" 2010 Teaching Award. An associate professor at the School of Library and Information Studies (SLIS) at the University of Alabama, Tuscaloosa, MacCall was nominated by Kathie Popadin, known as "Kpop" to the members of her cohort in the online MLIS program at SLIS. Sixteen of…

Evolution of radial profiles in regular Lemaitre-Tolman-Bondi dust models

International Nuclear Information System (INIS)

Sussman, Roberto A

2010-01-01

We undertake a comprehensive and rigorous analytic study of the evolution of radial profiles of covariant scalars in regular LemaItre-Tolman-Bondi (LTB) dust models. We consider specifically the phenomenon of 'profile inversions' in which an initial clump profile of density, spatial curvature or the expansion scalar might evolve into a void profile (and vice versa). Previous work in the literature on models with density void profiles and/or allowing for density profile inversions is given full generalization, with some erroneous results corrected. We prove rigorously that if an evolution without shell crossings is assumed, then only the 'clump to void' inversion can occur in density profiles, and only in hyperbolic models or regions with negative spatial curvature. The profiles of spatial curvature follow similar patterns as those of the density, with 'clump to void' inversions only possible for hyperbolic models or regions. However, profiles of the expansion scalar are less restrictive, with profile inversions necessarily taking place in elliptic models. We also examine radial profiles in special LTB configurations: closed elliptic models, models with a simultaneous big bang singularity, as well as a locally collapsing elliptic region surrounded by an expanding hyperbolic background. The general analytic statements that we obtain allow for setting up the right initial conditions to construct fully regular LTB models with any specific qualitative requirements for the profiles of all scalars and their time evolution. The results presented can be very useful in guiding future numerical work on these models and in revising previous analytic work on all their applications.

HMMEditor: a visual editing tool for profile hidden Markov model

Directory of Open Access Journals (Sweden)

Cheng Jianlin

2008-03-01

Full Text Available Abstract Background Profile Hidden Markov Model (HMM is a powerful statistical model to represent a family of DNA, RNA, and protein sequences. Profile HMM has been widely used in bioinformatics research such as sequence alignment, gene structure prediction, motif identification, protein structure prediction, and biological database search. However, few comprehensive, visual editing tools for profile HMM are publicly available. Results We develop a visual editor for profile Hidden Markov Models (HMMEditor. HMMEditor can visualize the profile HMM architecture, transition probabilities, and emission probabilities. Moreover, it provides functions to edit and save HMM and parameters. Furthermore, HMMEditor allows users to align a sequence against the profile HMM and to visualize the corresponding Viterbi path. Conclusion HMMEditor provides a set of unique functions to visualize and edit a profile HMM. It is a useful tool for biological sequence analysis and modeling. Both HMMEditor software and web service are freely available.

Approximate Stokes Drift Profiles and their use in Ocean Modelling

Science.gov (United States)

Breivik, Oyvind; Bidlot, Jea-Raymond; Janssen, Peter A. E. M.; Mogensen, Kristian

2016-04-01

Deep-water approximations to the Stokes drift velocity profile are explored as alternatives to the monochromatic profile. The alternative profiles investigated rely on the same two quantities required for the monochromatic profile, viz the Stokes transport and the surface Stokes drift velocity. Comparisons against parametric spectra and profiles under wave spectra from the ERA-Interim reanalysis and buoy observations reveal much better agreement than the monochromatic profile even for complex sea states. That the profiles give a closer match and a more correct shear has implications for ocean circulation models since the Coriolis-Stokes force depends on the magnitude and direction of the Stokes drift profile and Langmuir turbulence parameterizations depend sensitively on the shear of the profile. Of the two Stokes drift profiles explored here, the profile based on the Phillips spectrum is by far the best. In particular, the shear near the surface is almost identical to that influenced by the f-5 tail of spectral wave models. The NEMO general circulation ocean model was recently extended to incorporate the Stokes-Coriolis force along with two other wave-related effects. The ECWMF coupled atmosphere-wave-ocean ensemble forecast system now includes these wave effects in the ocean model component (NEMO).

Personalizing Web Search based on User Profile

OpenAIRE

Utage, Sharyu; Ahire, Vijaya

2016-01-01

Web Search engine is most widely used for information retrieval from World Wide Web. These Web Search engines help user to find most useful information. When different users Searches for same information, search engine provide same result without understanding who is submitted that query. Personalized web search it is search technique for proving useful result. This paper models preference of users as hierarchical user profiles. a framework is proposed called UPS. It generalizes profile and m...

Modeling the Radial Color Profile of M31

Directory of Open Access Journals (Sweden)

Semionov D.

2003-12-01

Full Text Available We present a preliminary study of a fragment of the radial color profile of the spiral galaxy M 31 in terms of 2-D model accounting for internal extinction in the disk. The two stellar population disk model was assumed. The old dust-free disk population is represented by the double exponential law, and the young disk population, well mixed with the dust, resides in spiral arms of various scale-heights. We find a good agreement among the radial color B-R profiles produced by this simple model and the profile measured around the spiral arm S4 of M 31.

Comparisons of Airborne HSRL and Modeled Aerosol Profiles

Science.gov (United States)

Ferrare, R. A.; Burton, S. P.; Hostetler, C. A.; Hair, J. W.; Ismail, S.; Rogers, R. R.; Notari, A.; Berkoff, T.; Butler, C. F.; Collins, J. E., Jr.; Fenn, M. A.; Scarino, A. J.; Clayton, M.; Mueller, D.; Chemyakin, E.; Fast, J. D.; Berg, L. K.; Randles, C. A.; Colarco, P. R.; daSilva, A.

2014-12-01

Aerosol profiles derived from a regional and a global model are compared with aerosol profiles acquired by NASA Langley Research Center (LaRC) airborne High Spectral Resolution Lidars (HSRLs) during recent field missions. We compare simulated aerosol profiles obtained from the WRF-Chem regional model with those measured by the airborne HSRL-2 instrument over the Atlantic Ocean east of Cape Cod in July 2012 during the Department of Energy Two-Column Aerosol Project (TCAP). While deployed on the LaRC King Air during TCAP, HSRL-2 acquired profiles of aerosol extinction at 355 and 532 nm, as well as aerosol backscatter and depolarization at 355, 532, and 1064 nm. Additional HSRL-2 data products include profiles of aerosol type, mixed layer depth, and aerosol microphysical parameters (e.g. effective radius, concentration). The HSRL-2 and WRF-Chem aerosol profiles are compared along the aircraft flight tracks. HSRL-2 profiles acquired during the NASA Deriving Information on Surface Conditions from COlumn and VERtically Resolved Observations Relevant to Air Quality (DISCOVER-AQ) mission over Houston during September 2013 are compared with the NASA Goddard Earth Observing System global model, version 5 (GEOS-5) profiles. In addition to comparing backscatter and extinction profiles, the fraction of aerosol extinction and optical thickness from various aerosol species from GEOS-5 are compared with aerosol extinction and optical thickness contributed by aerosol types derived from HSRL-2 data. We also compare aerosol profiles modeled by GEOS-5 with those measured by the airborne LaRC DIAL/HSRL instrument during August and September 2013 when it was deployed on the NASA DC-8 for the Studies of Emissions and Atmospheric Composition, Clouds and Climate Coupling by Regional Surveys (SEAC4RS) mission. DIAL/HSRL measured extinction (532 nm), backscatter (532 and 1064 nm), and depolarization profiles (532 and 1064 nm) in both nadir and zenith directions during long transects over the

Parent Prevention Communication Profiles and Adolescent Substance Use: A Latent Profile Analysis and Growth Curve Model

Science.gov (United States)

Choi, Hye Jeong; Miller-Day, Michelle; Shin, YoungJu; Hecht, Michael L.; Pettigrew, Jonathan; Krieger, Janice L.; Lee, JeongKyu; Graham, John W.

2017-01-01

This current study identifies distinct parent prevention communication profiles and examines whether youth with different parental communication profiles have varying substance use trajectories over time. Eleven schools in two rural school districts in the Midwestern United States were selected, and 784 students were surveyed at three time points from the beginning of 7th grade to the end of 8th grade. A series of latent profile analyses were performed to identify discrete profiles/subgroups of substance-specific prevention communication (SSPC). The results revealed a 4-profile model of SSPC: Active-Open, Passive-Open, Active-Silent, and Passive-Silent. A growth curve model revealed different rates of lifetime substance use depending on the youth’s SSPC profile. These findings have implications for parenting interventions and tailoring messages for parents to fit specific SSPC profiles. PMID:29056872

Modeling and clustering users with evolving profiles in usage streams

KAUST Repository

Zhang, Chongsheng; Masseglia, Florent; Zhang, Xiangliang

2012-01-01

Today, there is an increasing need of data stream mining technology to discover important patterns on the fly. Existing data stream models and algorithms commonly assume that users' records or profiles in data streams will not be updated or revised once they arrive. Nevertheless, in various applications such asWeb usage, the records/profiles of the users can evolve along time. This kind of streaming data evolves in two forms, the streaming of tuples or transactions as in the case of traditional data streams, and more importantly, the evolving of user records/profiles inside the streams. Such data streams bring difficulties on modeling and clustering for exploring users' behaviors. In this paper, we propose three models to summarize this kind of data streams, which are the batch model, the Evolving Objects (EO) model and the Dynamic Data Stream (DDS) model. Through creating, updating and deleting user profiles, these models summarize the behaviors of each user as a profile object. Based upon these models, clustering algorithms are employed to discover interesting user groups from the profile objects. We have evaluated all the proposed models on a large real-world data set, showing that the DDS model summarizes the data streams with evolving tuples more efficiently and effectively, and provides better basis for clustering users than the other two models. © 2012 IEEE.

Modeling and clustering users with evolving profiles in usage streams

KAUST Repository

Zhang, Chongsheng

2012-09-01

Today, there is an increasing need of data stream mining technology to discover important patterns on the fly. Existing data stream models and algorithms commonly assume that users\\' records or profiles in data streams will not be updated or revised once they arrive. Nevertheless, in various applications such asWeb usage, the records/profiles of the users can evolve along time. This kind of streaming data evolves in two forms, the streaming of tuples or transactions as in the case of traditional data streams, and more importantly, the evolving of user records/profiles inside the streams. Such data streams bring difficulties on modeling and clustering for exploring users\\' behaviors. In this paper, we propose three models to summarize this kind of data streams, which are the batch model, the Evolving Objects (EO) model and the Dynamic Data Stream (DDS) model. Through creating, updating and deleting user profiles, these models summarize the behaviors of each user as a profile object. Based upon these models, clustering algorithms are employed to discover interesting user groups from the profile objects. We have evaluated all the proposed models on a large real-world data set, showing that the DDS model summarizes the data streams with evolving tuples more efficiently and effectively, and provides better basis for clustering users than the other two models. © 2012 IEEE.

Receipts Assay Monitor: deadtime correction model and efficiency profile

International Nuclear Information System (INIS)

Weingardt, J.J.; Stewart, J.E.

1986-08-01

Experiments were performed at Los Alamos National Laboratory to characterize the operating parameters and flatten the axial efficiency profile of a neutron coincidence counter called the Receipts Assay Monitor (RAM). Optimum electronic settings determined by conventional methods included operating voltage (1680 V) and gate width (64 μs). Also determined were electronic characteristics such as bias and deadtime. Neutronic characteristics determined using a 252 Cf neutron source included axial efficiency profiles and axial die-away time profiles. The RAM electronics showed virtually no bias for coincidence count rate; it was measured as -4.6 x 10 -5 % with a standard deviation of 3.3 x 10 -4 %. Electronic deadtime was measured by two methods. The first method expresses the coincidence-rate deadtime as a linear function of the measured totals rate, and the second method treats deadtime as a constant. Initially, axial coincidence efficiency profiles yielded normalized efficiencies at the bottom and top of a 17-in. mockup UF 6 sample of 68.9% and 40.4%, respectively, with an average relative efficiency across the sample of 86.1%. Because the nature of the measurements performed with the RAM favors a much flatter efficiency profile, 3-mil cadmium sheets were wrapped around the 3 He tubes in selected locations to flatten the efficiency profile. Use of the cadmium sheets resulted in relative coincidence efficiencies at the bottom and top of the sample of 82.3% and 57.4%, respectively, with an average relative efficiency of 93.5%

Integrative structural modeling with small angle X-ray scattering profiles

Directory of Open Access Journals (Sweden)

Schneidman-Duhovny Dina

2012-07-01

Full Text Available Abstract Recent technological advances enabled high-throughput collection of Small Angle X-ray Scattering (SAXS profiles of biological macromolecules. Thus, computational methods for integrating SAXS profiles into structural modeling are needed more than ever. Here, we review specifically the use of SAXS profiles for the structural modeling of proteins, nucleic acids, and their complexes. First, the approaches for computing theoretical SAXS profiles from structures are presented. Second, computational methods for predicting protein structures, dynamics of proteins in solution, and assembly structures are covered. Third, we discuss the use of SAXS profiles in integrative structure modeling approaches that depend simultaneously on several data types.

Assessing call centers’ success:

Directory of Open Access Journals (Sweden)

Hesham A. Baraka

2013-07-01

This paper introduces a model to evaluate the performance of call centers based on the Delone and McLean Information Systems success model. A number of indicators are identified to track the call center’s performance. Mapping of the proposed indicators to the six dimensions of the D&M model is presented. A Weighted Call Center Performance Index is proposed to assess the call center performance; the index is used to analyze the effect of the identified indicators. Policy-Weighted approach was used to assume the weights with an analysis of different weights for each dimension. The analysis of the different weights cases gave priority to the User satisfaction and net Benefits dimension as the two outcomes from the system. For the input dimensions, higher priority was given to the system quality and the service quality dimension. Call centers decision makers can use the tool to tune the different weights in order to reach the objectives set by the organization. Multiple linear regression analysis was used in order to provide a linear formula for the User Satisfaction dimension and the Net Benefits dimension in order to be able to forecast the values for these two dimensions as function of the other dimensions

Inbound Call Centers and Emotional Dissonance in the Job Demands - Resources Model.

Science.gov (United States)

Molino, Monica; Emanuel, Federica; Zito, Margherita; Ghislieri, Chiara; Colombo, Lara; Cortese, Claudio G

2016-01-01

Emotional labor, defined as the process of regulating feelings and expressions as part of the work role, is a major characteristic in call centers. In particular, interacting with customers, agents are required to show certain emotions that are considered acceptable by the organization, even though these emotions may be different from their true feelings. This kind of experience is defined as emotional dissonance and represents a feature of the job especially for call center inbound activities. The present study was aimed at investigating whether emotional dissonance mediates the relationship between job demands (workload and customer verbal aggression) and job resources (supervisor support, colleague support, and job autonomy) on the one hand, and, on the other, affective discomfort, using the job demands-resources model as a framework. The study also observed differences between two different types of inbound activities: customer assistance service (CA) and information service. The study involved agents of an Italian Telecommunication Company, 352 of whom worked in the CA and 179 in the information service. The hypothesized model was tested across the two groups through multi-group structural equation modeling. Analyses showed that CA agents experience greater customer verbal aggression and emotional dissonance than information service agents. RESULTS also showed, only for the CA group, a full mediation of emotional dissonance between workload and affective discomfort, and a partial mediation of customer verbal aggression and job autonomy, and affective discomfort. This study's findings contributed both to the emotional labor literature, investigating the mediational role of emotional dissonance in the job demands-resources model, and to call center literature, considering differences between two specific kinds of inbound activities. Suggestions for organizations and practitioners emerged in order to identify practical implications useful both to support

Black-Scholes finite difference modeling in forecasting of call warrant prices in Bursa Malaysia

Science.gov (United States)

Mansor, Nur Jariah; Jaffar, Maheran Mohd

2014-07-01

Call warrant is a type of structured warrant in Bursa Malaysia. It gives the holder the right to buy the underlying share at a specified price within a limited period of time. The issuer of the structured warrants usually uses European style to exercise the call warrant on the maturity date. Warrant is very similar to an option. Usually, practitioners of the financial field use Black-Scholes model to value the option. The Black-Scholes equation is hard to solve analytically. Therefore the finite difference approach is applied to approximate the value of the call warrant prices. The central in time and central in space scheme is produced to approximate the value of the call warrant prices. It allows the warrant holder to forecast the value of the call warrant prices before the expiry date.

Statistical modelling of transcript profiles of differentially regulated genes

Directory of Open Access Journals (Sweden)

Sergeant Martin J

2008-07-01

Full Text Available Abstract Background The vast quantities of gene expression profiling data produced in microarray studies, and the more precise quantitative PCR, are often not statistically analysed to their full potential. Previous studies have summarised gene expression profiles using simple descriptive statistics, basic analysis of variance (ANOVA and the clustering of genes based on simple models fitted to their expression profiles over time. We report the novel application of statistical non-linear regression modelling techniques to describe the shapes of expression profiles for the fungus Agaricus bisporus, quantified by PCR, and for E. coli and Rattus norvegicus, using microarray technology. The use of parametric non-linear regression models provides a more precise description of expression profiles, reducing the "noise" of the raw data to produce a clear "signal" given by the fitted curve, and describing each profile with a small number of biologically interpretable parameters. This approach then allows the direct comparison and clustering of the shapes of response patterns between genes and potentially enables a greater exploration and interpretation of the biological processes driving gene expression. Results Quantitative reverse transcriptase PCR-derived time-course data of genes were modelled. "Split-line" or "broken-stick" regression identified the initial time of gene up-regulation, enabling the classification of genes into those with primary and secondary responses. Five-day profiles were modelled using the biologically-oriented, critical exponential curve, y(t = A + (B + CtRt + ε. This non-linear regression approach allowed the expression patterns for different genes to be compared in terms of curve shape, time of maximal transcript level and the decline and asymptotic response levels. Three distinct regulatory patterns were identified for the five genes studied. Applying the regression modelling approach to microarray-derived time course data

Analytical Call Center Model with Voice Response Unit and Wrap-Up Time

Directory of Open Access Journals (Sweden)

Petr Hampl

2015-01-01

Full Text Available The last twenty years of computer integration significantly changed the process of service in a call center service systems. Basic building modules of classical call centers – a switching system and a group of humans agents – was extended with other special modules such as skills-based routing module, automatic call distribution module, interactive voice response module and others to minimize the customer waiting time and wage costs. A calling customer of a modern call center is served in the first stage by the interactive voice response module without any human interaction. If the customer requirements are not satisfied in the first stage, the service continues to the second stage realized by the group of human agents. The service time of second stage – the average handle time – is divided into a conversation time and wrap-up time. During the conversation time, the agent answers customer questions and collects its requirements and during the wrap-up time (administrative time the agent completes the task without any customer interaction. The analytical model presented in this contribution is solved under the condition of statistical equilibrium and takes into account the interactive voice response module service time, the conversation time and the wrap-up time.

Modelling of Temperature Profiles and Transport Scaling in Auxiliary Heated Tokamaks

DEFF Research Database (Denmark)

Callen, J.D.; Christiansen, J.P.; Cordey, J.G.

1987-01-01

time , the heating effectiveness η, and the energy offset W(0). Considering both the temperature profile responses and the global transport scaling, the constant heat pinch or excess temperature gradient model is found to best characterize the present JET data. Finally, new methods are proposed......The temperature profiles produced by various heating profiles are calculated from local heat transport models. The models take the heat flux to be the sum of heat diffusion and a non-diffusive heat flow, consistent with local measurements of heat transport. Two models are developed analytically...... in detail: (i) a heat pinch or excess temperature gradient model with constant coefficients; and (ii) a non-linear heat diffusion coefficient (χ) model. Both models predict weak (lesssim20%) temperature profile responses to physically relevant changes in the heat deposition profile – primarily because...

Staffing to Maximize Profit for Call Centers with Impatient and Repeat-Calling Customers

Directory of Open Access Journals (Sweden)

Jun Gong

2015-01-01

Full Text Available Motivated by call center practice, we study the optimal staffing of many-server queues with impatient and repeat-calling customers. A call center is modeled as an M/M/s+M queue, which is developed to a behavioral queuing model in which customers come and go based on their satisfaction with waiting time. We explicitly take into account customer repeat behavior, which implies that satisfied customers might return and have an impact on the arrival rate. Optimality is defined as the number of agents that maximize revenues net of staffing costs, and we account for the characteristic that revenues are a direct function of staffing. Finally, we use numerical experiments to make certain comparisons with traditional models that do not consider customer repeat behavior. Furthermore, we indicate how managers might allocate staffing optimally with various customer behavior mechanisms.

Acoustic model optimisation for a call routing system

CSIR Research Space (South Africa)

Kleynhans, N

2012-11-01

Full Text Available Secretary system and provides background on some application-specific ASR issues. Section III details the ASR development effort as well as corpus selection and design. Our experiments are described Fig. 1. High level AutoSecretary call flow. in Section IV... and results and a discussion are presented in Section V. Lastly, the conclusion and possible future work appear in Section VI. II. BACKGROUND A. AutoSecretary IVR System Figure 1 shows the high level call flow of the AutoSecretary call routing system...

Simulation of internal transport barriers by means of the canonical profile transport model

International Nuclear Information System (INIS)

Dnestrovskij, Yu. N.; Cherkasov, S. V.; Dnestrovskij, A. Yu.; Lysenko, S. E.; Walsh, M. J.

2006-01-01

Models with critical gradients are widely used to describe energy balance in L-mode discharges. The so-called first critical gradient can be found from the canonical temperature profile. Here, it is suggested that discharge regimes with transport barriers can be described based on the idea of the second critical gradient. If, in a certain plasma region, the pressure gradient exceeds the second critical gradient, then the plasma bifurcates into a new state and a transport barrier forms in this region. This idea was implemented in a modified canonical profile transport model that makes it possible to describe the energy and particle balance in tokamak plasmas with arbitrary cross sections and aspect ratios. The magnitude of the second critical gradient was chosen by comparing the results calculated for several tokamak discharges with the experimental data. It is found that the second critical gradient is related to the magnetic shear s. The criterion of the transport barrier formation has the form (a 2 /r)d/drln(p/p c ) > z 0 (r), where r is the radial coordinate, a is the plasma minor radius, p is the plasma pressure, p c is the canonical pressure profile, and the dimensionless function z O (r) = C O + C 1 s (with C 0i ∼1, C 0e ∼3, and C 1i,e ∼2) describes the difference between the first and second critical gradients. Simulations show that this criterion is close to that obtained experimentally in JET. The model constructed here is used to simulate internal transport barriers in the JET, TFTR, DIII-D, and MAST tokamaks. The possible dependence of the second critical gradient on the plasma parameters is discussed

Hall Thruster Modeling with a Given Temperature Profile

International Nuclear Information System (INIS)

Dorf, L.; Semenov, V.; Raitses, Y.; Fisch, N.J.

2002-01-01

A quasi one-dimensional steady-state model of the Hall thruster is presented. For given mass flow rate, magnetic field profile, and discharge voltage the unique solution can be constructed, assuming that the thruster operates in one of the two regimes: with or without the anode sheath. It is shown that for a given temperature profile, the applied discharge voltage uniquely determines the operating regime; for discharge voltages greater than a certain value, the sheath disappears. That result is obtained over a wide range of incoming neutral velocities, channel lengths and widths, and cathode plane locations. A good correlation between the quasi one-dimensional model and experimental results can be achieved by selecting an appropriate temperature profile. We also show how the presented model can be used to obtain a two-dimensional potential distribution

A call for (trans)languaging: The language profiles at Roskilde University

DEFF Research Database (Denmark)

Daryai-Hansen, Petra; Barfod, Sonja; Schwarz, Lena

2016-01-01

in the humanities and social sciences. The students in the programme are explicitly asked to use translanguaging in order to enhance their languaging, i.e. they are invited to use translanguaging strategies in order to achieve interactional and social aims. The chapter introduces the design and the learning...... objectives of RUC’s language profiles. Furthermore we discuss, based on the language profiles as an example, how translanguaging practices and policies can be described on a supra, macro, meso, micro and nano level. The analysis focuses on teachers’ and students’ translanguaging practices and their attitudes...... towards translanguaging in language teaching/learning....

A three-parameter model for classifying anurans into four genera based on advertisement calls.

Science.gov (United States)

Gingras, Bruno; Fitch, William Tecumseh

2013-01-01

The vocalizations of anurans are innate in structure and may therefore contain indicators of phylogenetic history. Thus, advertisement calls of species which are more closely related phylogenetically are predicted to be more similar than those of distant species. This hypothesis was evaluated by comparing several widely used machine-learning algorithms. Recordings of advertisement calls from 142 species belonging to four genera were analyzed. A logistic regression model, using mean values for dominant frequency, coefficient of variation of root-mean square energy, and spectral flux, correctly classified advertisement calls with regard to genus with an accuracy above 70%. Similar accuracy rates were obtained using these parameters with a support vector machine model, a K-nearest neighbor algorithm, and a multivariate Gaussian distribution classifier, whereas a Gaussian mixture model performed slightly worse. In contrast, models based on mel-frequency cepstral coefficients did not fare as well. Comparable accuracy levels were obtained on out-of-sample recordings from 52 of the 142 original species. The results suggest that a combination of low-level acoustic attributes is sufficient to discriminate efficiently between the vocalizations of these four genera, thus supporting the initial premise and validating the use of high-throughput algorithms on animal vocalizations to evaluate phylogenetic hypotheses.

Voice Communications over 802.11 Ad Hoc Networks: Modeling, Optimization and Call Admission Control

Science.gov (United States)

Xu, Changchun; Xu, Yanyi; Liu, Gan; Liu, Kezhong

Supporting quality-of-service (QoS) of multimedia communications over IEEE 802.11 based ad hoc networks is a challenging task. This paper develops a simple 3-D Markov chain model for queuing analysis of IEEE 802.11 MAC layer. The model is applied for performance analysis of voice communications over IEEE 802.11 single-hop ad hoc networks. By using the model, we finish the performance optimization of IEEE MAC layer and obtain the maximum number of voice calls in IEEE 802.11 ad hoc networks as well as the statistical performance bounds. Furthermore, we design a fully distributed call admission control (CAC) algorithm which can provide strict statistical QoS guarantee for voice communications over IEEE 802.11 ad hoc networks. Extensive simulations indicate the accuracy of the analytical model and the CAC scheme.

Genomic outlier profile analysis: mixture models, null hypotheses, and nonparametric estimation.

Science.gov (United States)

Ghosh, Debashis; Chinnaiyan, Arul M

2009-01-01

In most analyses of large-scale genomic data sets, differential expression analysis is typically assessed by testing for differences in the mean of the distributions between 2 groups. A recent finding by Tomlins and others (2005) is of a different type of pattern of differential expression in which a fraction of samples in one group have overexpression relative to samples in the other group. In this work, we describe a general mixture model framework for the assessment of this type of expression, called outlier profile analysis. We start by considering the single-gene situation and establishing results on identifiability. We propose 2 nonparametric estimation procedures that have natural links to familiar multiple testing procedures. We then develop multivariate extensions of this methodology to handle genome-wide measurements. The proposed methodologies are compared using simulation studies as well as data from a prostate cancer gene expression study.

Inbound Call Centers and Emotional Dissonance in the Job Demands – Resources Model

Science.gov (United States)

Molino, Monica; Emanuel, Federica; Zito, Margherita; Ghislieri, Chiara; Colombo, Lara; Cortese, Claudio G.

2016-01-01

Background: Emotional labor, defined as the process of regulating feelings and expressions as part of the work role, is a major characteristic in call centers. In particular, interacting with customers, agents are required to show certain emotions that are considered acceptable by the organization, even though these emotions may be different from their true feelings. This kind of experience is defined as emotional dissonance and represents a feature of the job especially for call center inbound activities. Aim: The present study was aimed at investigating whether emotional dissonance mediates the relationship between job demands (workload and customer verbal aggression) and job resources (supervisor support, colleague support, and job autonomy) on the one hand, and, on the other, affective discomfort, using the job demands-resources model as a framework. The study also observed differences between two different types of inbound activities: customer assistance service (CA) and information service. Method: The study involved agents of an Italian Telecommunication Company, 352 of whom worked in the CA and 179 in the information service. The hypothesized model was tested across the two groups through multi-group structural equation modeling. Results: Analyses showed that CA agents experience greater customer verbal aggression and emotional dissonance than information service agents. Results also showed, only for the CA group, a full mediation of emotional dissonance between workload and affective discomfort, and a partial mediation of customer verbal aggression and job autonomy, and affective discomfort. Conclusion: This study’s findings contributed both to the emotional labor literature, investigating the mediational role of emotional dissonance in the job demands-resources model, and to call center literature, considering differences between two specific kinds of inbound activities. Suggestions for organizations and practitioners emerged in order to identify

OccuPeak: ChIP-Seq peak calling based on internal background modelling

NARCIS (Netherlands)

de Boer, Bouke A.; van Duijvenboden, Karel; van den Boogaard, Malou; Christoffels, Vincent M.; Barnett, Phil; Ruijter, Jan M.

2014-01-01

ChIP-seq has become a major tool for the genome-wide identification of transcription factor binding or histone modification sites. Most peak-calling algorithms require input control datasets to model the occurrence of background reads to account for local sequencing and GC bias. However, the

A model of phone call intervention in sensitizing the change of dietary pattern

Directory of Open Access Journals (Sweden)

Eliane Corrêa Chaves

2010-06-01

Full Text Available Objective: To propose a model of phone call intervention for changing dietary patterns and to assess its effectiveness. Method: A study carried out at the Health Promotion School of Medicine, University of São Paulo, with 27 subjects, 3-5 phone calls contacts per user, by means of which were given orientations and interventions on the principles of Cognitive Behavioral Therapy and the Transtheoretical Model on healthy eating. We analyzed the variables weight and body mass index, dietary patterns and overall stage of motivation to change. The data were submitted to analysis of variance with repeated measures at different stages of evaluation: pre-contact, 3rd and 5th phone calls. Results: After intervention, users showed a change in eating behavior in the third contact, and change occurred in weight and BMI in one patient. All findings were not statistically significant. There was improvement in the motivation to acquire new eating habits, also not significant. Conclusion: There was a slight change in feeding behavior, the motivation to change improved for all participants, without, however, have been effective in this type of approach.

Call Forecasting for Inbound Call Center

Directory of Open Access Journals (Sweden)

Peter Vinje

2009-01-01

Full Text Available In a scenario of inbound call center customer service, the ability to forecast calls is a key element and advantage. By forecasting the correct number of calls a company can predict staffing needs, meet service level requirements, improve customer satisfaction, and benefit from many other optimizations. This project will show how elementary statistics can be used to predict calls for a specific company, forecast the rate at which calls are increasing/decreasing, and determine if the calls may stop at some point.

Discrete Model Reference Adaptive Control System for Automatic Profiling Machine

Directory of Open Access Journals (Sweden)

Peng Song

2012-01-01

Full Text Available Automatic profiling machine is a movement system that has a high degree of parameter variation and high frequency of transient process, and it requires an accurate control in time. In this paper, the discrete model reference adaptive control system of automatic profiling machine is discussed. Firstly, the model of automatic profiling machine is presented according to the parameters of DC motor. Then the design of the discrete model reference adaptive control is proposed, and the control rules are proven. The results of simulation show that adaptive control system has favorable dynamic performances.

High-resolution mutational profiling suggests the genetic validity of glioblastoma patient-derived pre-clinical models.

Directory of Open Access Journals (Sweden)

Shawn E Yost

Full Text Available Recent advances in the ability to efficiently characterize tumor genomes is enabling targeted drug development, which requires rigorous biomarker-based patient selection to increase effectiveness. Consequently, representative DNA biomarkers become equally important in pre-clinical studies. However, it is still unclear how well these markers are maintained between the primary tumor and the patient-derived tumor models. Here, we report the comprehensive identification of somatic coding mutations and copy number aberrations in four glioblastoma (GBM primary tumors and their matched pre-clinical models: serum-free neurospheres, adherent cell cultures, and mouse xenografts. We developed innovative methods to improve the data quality and allow a strict comparison of matched tumor samples. Our analysis identifies known GBM mutations altering PTEN and TP53 genes, and new actionable mutations such as the loss of PIK3R1, and reveals clear patient-to-patient differences. In contrast, for each patient, we do not observe any significant remodeling of the mutational profile between primary to model tumors and the few discrepancies can be attributed to stochastic errors or differences in sample purity. Similarly, we observe ∼96% primary-to-model concordance in copy number calls in the high-cellularity samples. In contrast to previous reports based on gene expression profiles, we do not observe significant differences at the DNA level between in vitro compared to in vivo models. This study suggests, at a remarkable resolution, the genome-wide conservation of a patient's tumor genetics in various pre-clinical models, and therefore supports their use for the development and testing of personalized targeted therapies.

Models for estimating photosynthesis parameters from in situ production profiles

Science.gov (United States)

Kovač, Žarko; Platt, Trevor; Sathyendranath, Shubha; Antunović, Suzana

2017-12-01

The rate of carbon assimilation in phytoplankton primary production models is mathematically prescribed with photosynthesis irradiance functions, which convert a light flux (energy) into a material flux (carbon). Information on this rate is contained in photosynthesis parameters: the initial slope and the assimilation number. The exactness of parameter values is crucial for precise calculation of primary production. Here we use a model of the daily production profile based on a suite of photosynthesis irradiance functions and extract photosynthesis parameters from in situ measured daily production profiles at the Hawaii Ocean Time-series station Aloha. For each function we recover parameter values, establish parameter distributions and quantify model skill. We observe that the choice of the photosynthesis irradiance function to estimate the photosynthesis parameters affects the magnitudes of parameter values as recovered from in situ profiles. We also tackle the problem of parameter exchange amongst the models and the effect it has on model performance. All models displayed little or no bias prior to parameter exchange, but significant bias following parameter exchange. The best model performance resulted from using optimal parameter values. Model formulation was extended further by accounting for spectral effects and deriving a spectral analytical solution for the daily production profile. The daily production profile was also formulated with time dependent growing biomass governed by a growth equation. The work on parameter recovery was further extended by exploring how to extract photosynthesis parameters from information on watercolumn production. It was demonstrated how to estimate parameter values based on a linearization of the full analytical solution for normalized watercolumn production and from the solution itself, without linearization. The paper complements previous works on photosynthesis irradiance models by analysing the skill and consistency of

Modeling the wafer temperature profile in a multiwafer LPCVD furnace

Energy Technology Data Exchange (ETDEWEB)

Badgwell, T.A. [Rice Univ., Houston, TX (United States). Dept. of Chemical Engineering; Trachtenberg, I.; Edgar, T.F. [Univ. of Texas, Austin, TX (United States). Dept. of Chemical Engineering

1994-01-01

A mathematical model has been developed to predict wafer temperatures within a hot-wall multiwafer low pressure chemical vapor deposition (LPCVD) reactor. The model predicts both axial (wafer-to-wafer) and radial (across-wafer) temperature profiles. Model predictions compare favorably with in situ wafer temperature measurements described in an earlier paper. Measured axial and radial temperature nonuniformities are explained in terms of radiative heat-transfer effects. A simulation study demonstrates how changes in the outer tube temperature profile and reactor geometry affect wafer temperatures. Reactor design changes which could improve the wafer temperature profile are discussed.

The national psychological/personality profile of Romanians: An in depth analysis of the regional national psychological/personality profile of Romanians

Directory of Open Access Journals (Sweden)

David, D.

2015-12-01

Full Text Available In this article we perform an in depth analysis of the national psychological/personality profile of Romanians. Following recent developments in the field (see Rentfrow et al., 2013; 2015, we study the regional national psychological/personality profile of Romanians, based on the Big Five model (i.e., NEO PI/R. Using a representative sample (N1 = 1000, we performed a cluster analysis and identified two bipolar personality profiles in the population: cluster 1, called “Factor X-”, characterized by high neuroticism and low levels of extraversion, openness, agreeableness, and conscientiousness, and cluster 2, called “Factor X+”, characterized by the opposite configuration in personality traits, low neuroticism and high levels of extraversion, openness, agreeableness, and conscientiousness. The same two cluster pattern/solution emerged in other samples (N = 2200, with other Big Five-based instruments, and by using various methods of data (e.g., direct vs. reversed item score, controlling for item desirability and cluster (i.e., with and without “running means” analyses. These two profiles are quite evenly distributed in the overall population, but also across all geographical regions. Moreover, comparing the distribution of the five personality traits, we found just few small differences between the eight geographical divisions that we used for our analysis. These results suggest that the regional national psychological/personality profile of Romania is quite homogenous. Directions for harnessing the potential of both personality profiles are presented to the reader. Other implications based on the bipolar and fractal structure of the personality profile are discussed from an interdisciplinary perspective.

Modelling baryonic effects on galaxy cluster mass profiles

Science.gov (United States)

Shirasaki, Masato; Lau, Erwin T.; Nagai, Daisuke

2018-06-01

Gravitational lensing is a powerful probe of the mass distribution of galaxy clusters and cosmology. However, accurate measurements of the cluster mass profiles are limited by uncertainties in cluster astrophysics. In this work, we present a physically motivated model of baryonic effects on the cluster mass profiles, which self-consistently takes into account the impact of baryons on the concentration as well as mass accretion histories of galaxy clusters. We calibrate this model using the Omega500 hydrodynamical cosmological simulations of galaxy clusters with varying baryonic physics. Our model will enable us to simultaneously constrain cluster mass, concentration, and cosmological parameters using stacked weak lensing measurements from upcoming optical cluster surveys.

Modelling Baryonic Effects on Galaxy Cluster Mass Profiles

Science.gov (United States)

Shirasaki, Masato; Lau, Erwin T.; Nagai, Daisuke

2018-03-01

Gravitational lensing is a powerful probe of the mass distribution of galaxy clusters and cosmology. However, accurate measurements of the cluster mass profiles are limited by uncertainties in cluster astrophysics. In this work, we present a physically motivated model of baryonic effects on the cluster mass profiles, which self-consistently takes into account the impact of baryons on the concentration as well as mass accretion histories of galaxy clusters. We calibrate this model using the Omega500 hydrodynamical cosmological simulations of galaxy clusters with varying baryonic physics. Our model will enable us to simultaneously constrain cluster mass, concentration, and cosmological parameters using stacked weak lensing measurements from upcoming optical cluster surveys.

Application of high-resolution domestic electricity load profiles in network modelling

DEFF Research Database (Denmark)

Marszal, Anna Joanna; Mendaza, Iker Diaz de Cerio; Heiselberg, Per Kvols

2016-01-01

the generated profiles are inputted in a low-voltage network model created in DIgSILENT PowerFactory. By means of employing 1 hour based demand and generation profiles in during dynamic studies, the representation of the local power system performance might sometimes not be as accurate as needed. In the test...... with modeling when 1-minute domestic electricity demand and generation profiles are used as inputs. The analysis is done with a case study of low-voltage network located in Northern Denmark. The analysis includes two parts. The first part focuses on modeling the domestic demands and on-site generation in 1......-minute resolution. The load profiles of the household appliances are created using a bottom-up model, which uses the 1-minute cycle power use characteristics of a single appliance as the main building block. The profiles of heavy electric appliances, such as heat pump, are not included in the above...

Inbound Call Centers and Emotional Dissonance in the Job Demands – Resources Model

Directory of Open Access Journals (Sweden)

Monica Molino

2016-07-01

Full Text Available Background: Emotional labor, defined as the process of regulating feelings and expressions as part of the work role, is a major characteristic in call centers. In particular, interacting with customers, agents are required to show certain emotions that are considered acceptable by the organization, even though these emotions may be different from their true feelings. This kind of experience is defined as emotional dissonance and represents a feature of the job especially for call center inbound activities. Aim: The present study was aimed at investigating whether emotional dissonance mediates the relationship between job demands (workload and customer verbal aggression and job resources (supervisor support, colleague support and job autonomy on the one hand, and, on the other, affective discomfort, using the job demands-resources model as a framework. The study also observed differences between two different types of inbound activities: customer assistance service and information service.Method: The study involved agents of an Italian Telecommunication Company, 352 of whom worked in the customer assistance service and 179 in the information service. The hypothesized model was tested across the two groups through multi-group structural equation modeling.Results: Analyses showed that customer assistance service agents experience greater customer verbal aggression and emotional dissonance than information service agents. Results also showed, only for the customer assistance service group, a full mediation of emotional dissonance between workload and affective discomfort, and a partial mediation of customer verbal aggression and job autonomy, and affective discomfort.Conclusion: This study’s findings contributed both to the emotional labor literature, investigating the mediational role of emotional dissonance in the job demands-resources model, and to call center literature, considering differences between two specific kinds of inbound activities

Deep-depletion physics-based analytical model for scanning capacitance microscopy carrier profile extraction

International Nuclear Information System (INIS)

Wong, K. M.; Chim, W. K.

2007-01-01

An approach for fast and accurate carrier profiling using deep-depletion analytical modeling of scanning capacitance microscopy (SCM) measurements is shown for an ultrashallow p-n junction with a junction depth of less than 30 nm and a profile steepness of about 3 nm per decade change in carrier concentration. In addition, the analytical model is also used to extract the SCM dopant profiles of three other p-n junction samples with different junction depths and profile steepnesses. The deep-depletion effect arises from rapid changes in the bias applied between the sample and probe tip during SCM measurements. The extracted carrier profile from the model agrees reasonably well with the more accurate carrier profile from inverse modeling and the dopant profile from secondary ion mass spectroscopy measurements

Electoronic Performance Monitoring in Call Centers: An Ethical Decision Model

OpenAIRE

Perkins, David

2013-01-01

Ever since it emerged on a widespread basis in the 1990s, electronic performance monitoring of employees has received significant scrutiny in the literature. Call centers have been the focus of many of these studies. This particular study addresses the issue of electronic performance monitoring in call centers from an ethical perspective. The following ethical dilemma is offered: "Is it ethical for a call center manager to evaluate the performance of a call center employee using electronic pe...

Hidden Markov models for the activity profile of terrorist groups

OpenAIRE

Raghavan, Vasanthan; Galstyan, Aram; Tartakovsky, Alexander G.

2012-01-01

The main focus of this work is on developing models for the activity profile of a terrorist group, detecting sudden spurts and downfalls in this profile, and, in general, tracking it over a period of time. Toward this goal, a $d$-state hidden Markov model (HMM) that captures the latent states underlying the dynamics of the group and thus its activity profile is developed. The simplest setting of $d=2$ corresponds to the case where the dynamics are coarsely quantized as Active and Inactive, re...

Probabilistic Anomaly Detection Based On System Calls Analysis

Directory of Open Access Journals (Sweden)

Przemysław Maciołek

2007-01-01

Full Text Available We present an application of probabilistic approach to the anomaly detection (PAD. Byanalyzing selected system calls (and their arguments, the chosen applications are monitoredin the Linux environment. This allows us to estimate “(abnormality” of their behavior (bycomparison to previously collected profiles. We’ve attached results of threat detection ina typical computer environment.

Accelerated Profile HMM Searches.

Directory of Open Access Journals (Sweden)

Sean R Eddy

2011-10-01

Full Text Available Profile hidden Markov models (profile HMMs and probabilistic inference methods have made important contributions to the theory of sequence database homology search. However, practical use of profile HMM methods has been hindered by the computational expense of existing software implementations. Here I describe an acceleration heuristic for profile HMMs, the "multiple segment Viterbi" (MSV algorithm. The MSV algorithm computes an optimal sum of multiple ungapped local alignment segments using a striped vector-parallel approach previously described for fast Smith/Waterman alignment. MSV scores follow the same statistical distribution as gapped optimal local alignment scores, allowing rapid evaluation of significance of an MSV score and thus facilitating its use as a heuristic filter. I also describe a 20-fold acceleration of the standard profile HMM Forward/Backward algorithms using a method I call "sparse rescaling". These methods are assembled in a pipeline in which high-scoring MSV hits are passed on for reanalysis with the full HMM Forward/Backward algorithm. This accelerated pipeline is implemented in the freely available HMMER3 software package. Performance benchmarks show that the use of the heuristic MSV filter sacrifices negligible sensitivity compared to unaccelerated profile HMM searches. HMMER3 is substantially more sensitive and 100- to 1000-fold faster than HMMER2. HMMER3 is now about as fast as BLAST for protein searches.

On the appropriate definition of soil profile configuration and initial conditions for land surface-hydrology models in cold regions

Science.gov (United States)

Sapriza-Azuri, Gonzalo; Gamazo, Pablo; Razavi, Saman; Wheater, Howard S.

2018-06-01

Arctic and subarctic regions are amongst the most susceptible regions on Earth to global warming and climate change. Understanding and predicting the impact of climate change in these regions require a proper process representation of the interactions between climate, carbon cycle, and hydrology in Earth system models. This study focuses on land surface models (LSMs) that represent the lower boundary condition of general circulation models (GCMs) and regional climate models (RCMs), which simulate climate change evolution at the global and regional scales, respectively. LSMs typically utilize a standard soil configuration with a depth of no more than 4 m, whereas for cold, permafrost regions, field experiments show that attention to deep soil profiles is needed to understand and close the water and energy balances, which are tightly coupled through the phase change. To address this gap, we design and run a series of model experiments with a one-dimensional LSM, called CLASS (Canadian Land Surface Scheme), as embedded in the MESH (Modélisation Environmentale Communautaire - Surface and Hydrology) modelling system, to (1) characterize the effect of soil profile depth under different climate conditions and in the presence of parameter uncertainty; (2) assess the effect of including or excluding the geothermal flux in the LSM at the bottom of the soil column; and (3) develop a methodology for temperature profile initialization in permafrost regions, where the system has an extended memory, by the use of paleo-records and bootstrapping. Our study area is in Norman Wells, Northwest Territories of Canada, where measurements of soil temperature profiles and historical reconstructed climate data are available. Our results demonstrate a dominant role for parameter uncertainty, that is often neglected in LSMs. Considering such high sensitivity to parameter values and dependency on the climate condition, we show that a minimum depth of 20 m is essential to adequately represent

Developing a univariate approach to phase-I monitoring of fuzzy quality profiles

Directory of Open Access Journals (Sweden)

Kazem Noghondarian

2012-10-01

Full Text Available In many real-world applications, the quality of a process or a particular product can be characterized by a functional relationship called profile. A profile builds the relationships between a response quality characteristic and one or more explanatory variables. Monitoring the quality of a profile is implemented to understand and to verify the stability of this functional relationship over time. In some real applications, a fuzzy linear regression model can represent the profile adequately where the response quality characteristic is fuzzy. The purpose of this paper is to develop an approach for monitoring process/product profiles in fuzzy environment. A model in fuzzy linear regression is developed to construct the quality profiles by using linear programming and then fuzzy individuals and moving-range (I-MR control charts are developed to monitor both intercept and slope of fuzzy profiles to achieve an in-control process. A case study in customer satisfaction is presented to show the application of our approach and to express the sensitivity analysis of parameters for building a fuzzy profile.

Psychological profile: the problem of modeling the unknown criminal personality

Directory of Open Access Journals (Sweden)

Г. М. Гетьман

2013-10-01

Full Text Available The article investigates the problem of modeling an unknown person in the preparation of criminal psychological profile. Some approaches to the concept of "psychological profile" and "psychological portrait", in particular the proposed delineation of these terms. We consider the system steps in the development of the psychological profile of an unknown perpetrator.

Acoustic model optimisation for a call routing system

CSIR Research Space (South Africa)

Kleynhans, N

2012-11-01

Full Text Available and results and a discussion are presented in Section V. Lastly, the conclusion and possible future work appear in Section VI. II. BACKGROUND A. AutoSecretary IVR System Figure 1 shows the high level call flow of the AutoSecretary call routing system... to be difficult Corpus Name # utterances duration in hours Lwazi English 5843 5.03 Lwazi English plus Lwazi language prompts 7770 5.57 NCHLT English 106018 76.97 AST English (5 dialects) 51745 29.80 TABLE I THE NUMBER OF TRAINING UTTERANCES AND DURATION...

A varying coefficient model to measure the effectiveness of mass media anti-smoking campaigns in generating calls to a Quitline.

Science.gov (United States)

Bui, Quang M; Huggins, Richard M; Hwang, Wen-Han; White, Victoria; Erbas, Bircan

2010-01-01

Anti-smoking advertisements are an effective population-based smoking reduction strategy. The Quitline telephone service provides a first point of contact for adults considering quitting. Because of data complexity, the relationship between anti-smoking advertising placement, intensity, and time trends in total call volume is poorly understood. In this study we use a recently developed semi-varying coefficient model to elucidate this relationship. Semi-varying coefficient models comprise parametric and nonparametric components. The model is fitted to the daily number of calls to Quitline in Victoria, Australia to estimate a nonparametric long-term trend and parametric terms for day-of-the-week effects and to clarify the relationship with target audience rating points (TARPs) for the Quit and nicotine replacement advertising campaigns. The number of calls to Quitline increased with the TARP value of both the Quit and other smoking cessation advertisement; the TARP values associated with the Quit program were almost twice as effective. The varying coefficient term was statistically significant for peak periods with little or no advertising. Semi-varying coefficient models are useful for modeling public health data when there is little or no information on other factors related to the at-risk population. These models are well suited to modeling call volume to Quitline, because the varying coefficient allowed the underlying time trend to depend on fixed covariates that also vary with time, thereby explaining more of the variation in the call model.

Call center performance with direct response advertising

NARCIS (Netherlands)

M. Kiygi Calli (Meltem); M. Weverbergh (Marcel); Ph.H.B.F. Franses (Philip Hans)

2017-01-01

textabstractThis study investigates the manpower planning and the performance of a national call center dealing with car repairs and on the road interventions. We model the impact of advertising on the capacity required. The starting point is a forecasting model for the incoming calls, where we take

Semi-analytical model of laser resonance absorption in plasmas with a parabolic density profile

International Nuclear Information System (INIS)

Pestehe, S J; Mohammadnejad, M

2010-01-01

Analytical expressions for mode conversion and resonance absorption of electromagnetic waves in inhomogeneous, unmagnetized plasmas are required for laboratory and simulation studies. Although most of the analyses of this problem have concentrated on the linear plasma density profile, there are a few research works that deal with different plasma density profiles including the parabolic profile. Almost none of them could give clear analytical formulae for the electric and magnetic components of the electromagnetic field propagating through inhomogeneous plasmas. In this paper, we have considered the resonant absorption of laser light near the critical density of plasmas with parabolic electron density profiles followed by a uniform over-dense region and have obtained expressions for the electric and magnetic vectors of laser light propagating through the plasma. An estimation of the fractional absorption of laser energy has also been carried out. It has been shown that, in contrast to the linear density profile, the energy absorption depends explicitly on the value of collision frequency as well as on a new parameter, N, called the over-dense density order.

Further Examining Berry's Model: The Applicability of Latent Profile Analysis to Acculturation

Science.gov (United States)

Fox, Rina S.; Merz, Erin L.; Solórzano, Martha T.; Roesch, Scott C.

2013-01-01

This study used latent profile analysis (LPA) to identify acculturation profiles. A three-profile solution fit the data best, and comparisons on demographic and psychosocial outcomes as a function of profile yielded expected results. The findings support using LPA as a parsimonious way to model acculturation without anticipating profiles in…

An empirical analysis of the corporate call decision

International Nuclear Information System (INIS)

Carlson, M.D.

1998-01-01

An economic study of the the behaviour of financial managers of utility companies was presented. The study examined whether or not an option pricing based model of the call decision does a better job of explaining callable preferred share prices and call decisions compared to other models. In this study, the Rust (1987) empirical technique was extended to include the use of information from preferred share prices in addition to the call decisions. Reasonable estimates were obtained from data of shares of the Pacific Gas and Electric Company (PGE) for the transaction costs associated with a call. It was concluded that the managers of the PGE clearly take into account the value of the option to delay the call when making their call decisions

An ontology-based nurse call management system (oNCS) with probabilistic priority assessment

Science.gov (United States)

2011-01-01

Background The current, place-oriented nurse call systems are very static. A patient can only make calls with a button which is fixed to a wall of a room. Moreover, the system does not take into account various factors specific to a situation. In the future, there will be an evolution to a mobile button for each patient so that they can walk around freely and still make calls. The system would become person-oriented and the available context information should be taken into account to assign the correct nurse to a call. The aim of this research is (1) the design of a software platform that supports the transition to mobile and wireless nurse call buttons in hospitals and residential care and (2) the design of a sophisticated nurse call algorithm. This algorithm dynamically adapts to the situation at hand by taking the profile information of staff members and patients into account. Additionally, the priority of a call probabilistically depends on the risk factors, assigned to a patient. Methods The ontology-based Nurse Call System (oNCS) was developed as an extension of a Context-Aware Service Platform. An ontology is used to manage the profile information. Rules implement the novel nurse call algorithm that takes all this information into account. Probabilistic reasoning algorithms are designed to determine the priority of a call based on the risk factors of the patient. Results The oNCS system is evaluated through a prototype implementation and simulations, based on a detailed dataset obtained from Ghent University Hospital. The arrival times of nurses at the location of a call, the workload distribution of calls amongst nurses and the assignment of priorities to calls are compared for the oNCS system and the current, place-oriented nurse call system. Additionally, the performance of the system is discussed. Conclusions The execution time of the nurse call algorithm is on average 50.333 ms. Moreover, the oNCS system significantly improves the assignment of nurses

An ontology-based nurse call management system (oNCS with probabilistic priority assessment

Directory of Open Access Journals (Sweden)

Verhoeve Piet

2011-02-01

Full Text Available Abstract Background The current, place-oriented nurse call systems are very static. A patient can only make calls with a button which is fixed to a wall of a room. Moreover, the system does not take into account various factors specific to a situation. In the future, there will be an evolution to a mobile button for each patient so that they can walk around freely and still make calls. The system would become person-oriented and the available context information should be taken into account to assign the correct nurse to a call. The aim of this research is (1 the design of a software platform that supports the transition to mobile and wireless nurse call buttons in hospitals and residential care and (2 the design of a sophisticated nurse call algorithm. This algorithm dynamically adapts to the situation at hand by taking the profile information of staff members and patients into account. Additionally, the priority of a call probabilistically depends on the risk factors, assigned to a patient. Methods The ontology-based Nurse Call System (oNCS was developed as an extension of a Context-Aware Service Platform. An ontology is used to manage the profile information. Rules implement the novel nurse call algorithm that takes all this information into account. Probabilistic reasoning algorithms are designed to determine the priority of a call based on the risk factors of the patient. Results The oNCS system is evaluated through a prototype implementation and simulations, based on a detailed dataset obtained from Ghent University Hospital. The arrival times of nurses at the location of a call, the workload distribution of calls amongst nurses and the assignment of priorities to calls are compared for the oNCS system and the current, place-oriented nurse call system. Additionally, the performance of the system is discussed. Conclusions The execution time of the nurse call algorithm is on average 50.333 ms. Moreover, the oNCS system significantly improves

Low-level profiling and MARTE-compatible modeling of software components for real-time systems

NARCIS (Netherlands)

Triantafyllidis, K.; Bondarev, E.; With, de P.H.N.

2012-01-01

In this paper, we present a method for (a) profiling of individual components at high accuracy level, (b) modeling of the components with the accurate data obtained from profiling, and (c) model conversion to the MARTE profile. The resulting performance models of individual components are used at

Sensitivity of molecular marker-based CMB models to biomass burning source profiles

Science.gov (United States)

Sheesley, Rebecca J.; Schauer, James J.; Zheng, Mei; Wang, Bo

To assess the contribution of sources to fine particulate organic carbon (OC) at four sites in North Carolina, USA, a molecular marker chemical mass balance model (MM-CMB) was used to quantify seasonal contributions for 2 years. The biomass burning contribution at these sites was found to be 30-50% of the annual OC concentration. In order to provide a better understanding of the uncertainty in MM-CMB model results, a biomass burning profile sensitivity test was performed on the 18 seasonal composites. The results using reconstructed emission profiles based on published profiles compared well, while model results using a single source test profile resulted in biomass burning contributions that were more variable. The biomass burning contribution calculated using an average regional profile of fireplace emissions from five southeastern tree species also compared well with an average profile of open burning of pine-dominated forest from Georgia. The standard deviation of the results using different source profiles was a little over 30% of the annual average biomass contributions. Because the biomass burning contribution accounted for 30-50% of the OC at these sites, the choice of profile also impacted the motor vehicle source attribution due to the common emission of elemental carbon and polycyclic aromatic hydrocarbons. The total mobile organic carbon contribution was less effected by the biomass burning profile than the relative contributions from gasoline and diesel engines.

Testing Two Nutrient Profiling Models of Labelled Foods and Beverages Marketed in Turkey.

Science.gov (United States)

Dikmen, Derya; Kızıl, Mevlüde; Uyar, Muhemmet Fatih; Pekcan, Gülden

2015-06-01

The objective of this study was to evaluate the nutrient profile of labelled foods and also understand the application of two international nutrient profiling models of labelled foods and beverages. WXYfm and NRF 9.3 nutrient profiling models were used to evaluate 3,171 labelled foods and beverages of 38 food categories and 500 different brands. According to the WXYfm model, pasta, grains and legumes and frozen foods had the best scores whereas oils had the worst scores. According to the NRF 9.3 model per 100 kcal, the best scores were obtained for frozen foods, grains and legumes and milk products whereas the confectionery foods had the worst scores. According to NRF 9.3 per serving size, grains and legumes had the best scores and flavoured milks had the worst scores. A comparison of WXYfm and NRF 9.3 nutrient profiling models ranked scores showed a high positive correlation (p=0.01). The two nutrient models evaluated yielded similar results. Further studies are needed to test other category specific nutrient profiling models in order to understand how different models behave. Copyright© by the National Institute of Public Health, Prague 2015.

Sensitivity of the urban airshed model to mixing height profiles

Energy Technology Data Exchange (ETDEWEB)

Rao, S.T.; Sistla, G.; Ku, J.Y.; Zhou, N.; Hao, W. [New York State Dept. of Environmental Conservation, Albany, NY (United States)

1994-12-31

The United States Environmental Protection Agency (USEPA) has recommended the use of the Urban Airshed Model (UAM), a grid-based photochemical model, for regulatory applications. One of the important parameters in applications of the UAM is the height of the mixed layer or the diffusion break. In this study, we examine the sensitivity of the UAM-predicted ozone concentrations to (a) a spatially invariant diurnal mixing height profile, and (b) a spatially varying diurnal mixing height profile for a high ozone episode of July 1988 for the New York Airshed. The 1985/88 emissions inventory used in the EPA`s Regional Oxidant Modeling simulations has been regridded for this study. Preliminary results suggest that the spatially varying case yields a higher peak ozone concentrations compared to the spatially invariant mixing height simulation, with differences in the peak ozone ranging from a few ppb to about 40 ppb for the days simulated. These differences are attributed to the differences in the shape of the mixing height profiles and its rate of growth during the morning hours when peak emissions are injected into the atmosphere. Examination of the impact of emissions reductions associated with these two mixing height profiles indicates that NO{sub x}-focussed controls provide a greater change in the predicted ozone peak under spatially invariant mixing heights than under the spatially varying mixing height profile. On the other hand, VOC-focussed controls provide a greater change in the predicted peak ozone levels under spatially varying mixing heights than under the spatially invariant mixing height profile.

Penentuan Nilai Opsi Call Eropa Dengan Pembayaran Dividen

Directory of Open Access Journals (Sweden)

Diana Purwandari

2016-08-01

Full Text Available Fluktuasi harga saham menyebabkan perdagangan saham memiliki resiko. Opsi merupakan alternatif untuk mengurangi resiko dalam perdagangan saham. Opsi Eropa adalah suatu kontrak keuangan yang memberikan hak, bukan kewajiban, kepada holder, untuk membeli atau menjual aset pokok dari writer pada saat jatuh tempo dengan harga yang sudah ditentukan. Model penilaian harga opsi yang banyak diterima dalam bidang finansial adalah model Black-Scholes. Tujuan dari penelitian ini adalah mengetahui pengaruh pembagian dividen terhadap harga saham dan menentukan nilai opsi call Eropa dengan pembayaran dividen pada waktu yang telah ditentukan. Nilai opsi call Eropa dengan pembayaran dividen pada waktu yang telah ditentukan diperoleh menggunakan integrasi numerik dengan metode Simpson sebesar 12,6388.Kata kunci: opsi call Eropa, model Black-Scholes, dividen, metode Simpson.ABSTRACT Fluctuations in stock prices lead stock trading risk. An alternative options to reduce the risk in stock trading. European option is a financial contract that gives the right, but not the obligation, to the holder, to buy or sell the underlying asset of the writer at the maturity date at a price specified. Option price valuation models are widely accepted in the field of finance is the Black-Scholes model. The purpose of this study is to determine the effect of dividend distribution to the stock price and determine the value of the European call option with dividend payments at a predetermined time. Value of the European call option with dividend payments at a predetermined time obtained using numerical integration with Simpson method of 12,6388.Key words: European call options, Black-Scholes model, dividend, Simpson method.

Measured and modelled concentrations and vertical profiles of airborne particulate matter within the boundary layer of a street canyon

International Nuclear Information System (INIS)

Colls, J.J.; Micallef, A.

1999-01-01

Concentrations and vertical profiles of various fractions of airborne particulate matter (suspended particulate matter (SPM), PM 10 and PM 2.5 ) have been measured over the first three metres from ground in a street canyon. Measurements were carried out using automated near real-time apparatus called the Kinetic Sequential Sampling (KSS) system. KSS system is essentially an electronically-controlled lift carrying a real-time particle monitor for sampling air sequentially, at different heights within the breathing zone, which includes all heights within the surface layer of a street canyon at which people may breathe. Data is automatically logged at the different receptor levels, for the determination of the average vertical concentration profile of airborne particulate matter. For measuring the airborne particle concentration, a Grimm Dust Monitor 1.104/5 was used. The recorded data also allows for time series analysis of airborne particulate matter concentration at different heights. Time series data and hourly-average vertical concentration profiles in the boundary layer of the confines of a street are thought to be mainly determined by traffic emissions and traffic associated processes. Hence the measured data were compared with results of a street canyon emission-dispersion model in time and space. This Street Level Air Quality (SLAQ) model employs the plume-box technique and includes modules for simulating vehicle-generated effects such as thermally- and mechanically-generated turbulence and resuspension of road dust. Environmental processes, such as turbulence resulting from surface sensible heat and the formation of sulphate aerosol from sulphur dioxide exhaust emissions, are taken into account. The paper presents an outline description of the measuring technique and model used, and a comparison of the measured and modelled data

LinkImputeR: user-guided genotype calling and imputation for non-model organisms.

Science.gov (United States)

Money, Daniel; Migicovsky, Zoë; Gardner, Kyle; Myles, Sean

2017-07-10

Genomic studies such as genome-wide association and genomic selection require genome-wide genotype data. All existing technologies used to create these data result in missing genotypes, which are often then inferred using genotype imputation software. However, existing imputation methods most often make use only of genotypes that are successfully inferred after having passed a certain read depth threshold. Because of this, any read information for genotypes that did not pass the threshold, and were thus set to missing, is ignored. Most genomic studies also choose read depth thresholds and quality filters without investigating their effects on the size and quality of the resulting genotype data. Moreover, almost all genotype imputation methods require ordered markers and are therefore of limited utility in non-model organisms. Here we introduce LinkImputeR, a software program that exploits the read count information that is normally ignored, and makes use of all available DNA sequence information for the purposes of genotype calling and imputation. It is specifically designed for non-model organisms since it requires neither ordered markers nor a reference panel of genotypes. Using next-generation DNA sequence (NGS) data from apple, cannabis and grape, we quantify the effect of varying read count and missingness thresholds on the quantity and quality of genotypes generated from LinkImputeR. We demonstrate that LinkImputeR can increase the number of genotype calls by more than an order of magnitude, can improve genotyping accuracy by several percent and can thus improve the power of downstream analyses. Moreover, we show that the effects of quality and read depth filters can differ substantially between data sets and should therefore be investigated on a per-study basis. By exploiting DNA sequence data that is normally ignored during genotype calling and imputation, LinkImputeR can significantly improve both the quantity and quality of genotype data generated from

ACER Mathematics Profile Series: Number Test. (Test Booklet, Answer and Record Sheet, Score Key, and Teachers Handbook).

Science.gov (United States)

Cornish, Greg; Wines, Robin

The Number Test of the ACER Mathematics Profile Series, contains 30 items, for each of three suggested grade levels: 7-8, 8-9, and 9-10. Raw scores on all tests in the ACER Mathematics Profile Series (Number, Operations, Space and Measurement) are converted to a common scale called MAPS, a major feature of the Series. Based on the Rasch Model,…

On the appropriate definition of soil profile configuration and initial conditions for land surface–hydrology models in cold regions

Directory of Open Access Journals (Sweden)

G. Sapriza-Azuri

2018-06-01

Full Text Available Arctic and subarctic regions are amongst the most susceptible regions on Earth to global warming and climate change. Understanding and predicting the impact of climate change in these regions require a proper process representation of the interactions between climate, carbon cycle, and hydrology in Earth system models. This study focuses on land surface models (LSMs that represent the lower boundary condition of general circulation models (GCMs and regional climate models (RCMs, which simulate climate change evolution at the global and regional scales, respectively. LSMs typically utilize a standard soil configuration with a depth of no more than 4 m, whereas for cold, permafrost regions, field experiments show that attention to deep soil profiles is needed to understand and close the water and energy balances, which are tightly coupled through the phase change. To address this gap, we design and run a series of model experiments with a one-dimensional LSM, called CLASS (Canadian Land Surface Scheme, as embedded in the MESH (Modélisation Environmentale Communautaire – Surface and Hydrology modelling system, to (1 characterize the effect of soil profile depth under different climate conditions and in the presence of parameter uncertainty; (2 assess the effect of including or excluding the geothermal flux in the LSM at the bottom of the soil column; and (3 develop a methodology for temperature profile initialization in permafrost regions, where the system has an extended memory, by the use of paleo-records and bootstrapping. Our study area is in Norman Wells, Northwest Territories of Canada, where measurements of soil temperature profiles and historical reconstructed climate data are available. Our results demonstrate a dominant role for parameter uncertainty, that is often neglected in LSMs. Considering such high sensitivity to parameter values and dependency on the climate condition, we show that a minimum depth of 20 m is essential to

Profile-driven regression for modeling and runtime optimization of mobile networks

DEFF Research Database (Denmark)

McClary, Dan; Syrotiuk, Violet; Kulahci, Murat

2010-01-01

Computer networks often display nonlinear behavior when examined over a wide range of operating conditions. There are few strategies available for modeling such behavior and optimizing such systems as they run. Profile-driven regression is developed and applied to modeling and runtime optimization...... of throughput in a mobile ad hoc network, a self-organizing collection of mobile wireless nodes without any fixed infrastructure. The intermediate models generated in profile-driven regression are used to fit an overall model of throughput, and are also used to optimize controllable factors at runtime. Unlike...

Use of profile hidden Markov models in viral discovery: current insights

Directory of Open Access Journals (Sweden)

Reyes A

2017-07-01

Full Text Available Alejandro Reyes,1–3 João Marcelo P Alves,4 Alan Mitchell Durham,5 Arthur Gruber4 1Department of Biological Sciences, Universidad de los Andes, Bogotá, Colombia; 2Department of Pathology and Immunology, Center for Genome Sciences and Systems Biology, Washington University in Saint Louis, St Louis, MO, USA; 3Max Planck Tandem Group in Computational Biology, Universidad de los Andes, Bogotá, Colombia; 4Department of Parasitology, Institute of Biomedical Sciences, 5Department of Computer Science, Institute of Mathematics and Statistics, Universidade de São Paulo, São Paulo, Brazil Abstract: Sequence similarity searches are the bioinformatic cornerstone of molecular sequence analysis for all domains of life. However, large amounts of divergence between organisms, such as those seen among viruses, can significantly hamper analyses. Profile hidden Markov models (profile HMMs are among the most successful approaches for dealing with this problem, which represent an invaluable tool for viral identification efforts. Profile HMMs are statistical models that convert information from a multiple sequence alignment into a set of probability values that reflect position-specific variation levels in all members of evolutionarily related sequences. Since profile HMMs represent a wide spectrum of variation, these models show higher sensitivity than conventional similarity methods such as BLAST for the detection of remote homologs. In recent years, there has been an effort to compile viral sequences from different viral taxonomic groups into integrated databases, such as Prokaryotic Virus Orthlogous Groups (pVOGs and database of profile HMMs (vFam database, which provide functional annotation, multiple sequence alignments, and profile HMMs. Since these databases rely on viral sequences collected from GenBank and RefSeq, they suffer in variable extent from uneven taxonomic sampling, with low sequence representation of many viral groups, which affects the

Turchin's Relation for Call-by-Name Computations: A Formal Approach

Directory of Open Access Journals (Sweden)

Antonina Nepeivoda

2016-07-01

Full Text Available Supercompilation is a program transformation technique that was first described by V. F. Turchin in the 1970s. In supercompilation, Turchin's relation as a similarity relation on call-stack configurations is used both for call-by-value and call-by-name semantics to terminate unfolding of the program being transformed. In this paper, we give a formal grammar model of call-by-name stack behaviour. We classify the model in terms of the Chomsky hierarchy and then formally prove that Turchin's relation can terminate all computations generated by the model.

Physical and profile oceanographic data collected aboard the Brooks McCall in the Gulf of Mexico from 2010-09-02 to 2010-09-06 in response to the Deepwater Horizon Oil Spill event (NODC Accession 0084590)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Physical and profile oceanographic data were collected aboard the Brooks McCall in the Gulf of Mexico from 2010-09-02 to 2010-09-06 in response to the Deepwater...

Physical and profile oceanographic data collected aboard the Brooks McCall in the Gulf of Mexico from 2010-08-29 to 2010-09-02 in response to the Deepwater Horizon Oil Spill event (NODC Accession 0084589)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Physical and profile oceanographic data were collected aboard the Brooks McCall in the Gulf of Mexico from 2010-08-29 to 2010-09-02 in response to the Deepwater...

Call Admission Scheme for Multidimensional Traffic Assuming Finite Handoff User

Directory of Open Access Journals (Sweden)

Md. Baitul Al Sadi

2017-01-01

Full Text Available Usually, the number of users within a cell in a mobile cellular network is considered infinite; hence, M/M/n/k model is appropriate for new originated traffic, but the number of ongoing calls around a cell is always finite. Hence, the traffic model of handoff call will be M/M/n/k/N. In this paper, a K-dimensional traffic model of a mobile cellular network is proposed using the combination of limited and unlimited users case. A new call admission scheme (CAS is proposed based on both thinning scheme and fading condition. The fading condition of the wireless channel access to a handoff call is prioritized compared to newly originated calls.

Performance indicators for call centers with impatience

NARCIS (Netherlands)

Jouini, O.; Koole, G.M.; Roubos, A.

2013-01-01

An important feature of call center modeling is the presence of impatient customers. This article considers single-skill call centers including customer abandonments. A number of different service-level definitions are structured, including all those used in practice, and the explicit computation of

Towards an Enhancement of Organizational Information Security through Threat Factor Profiling (TFP) Model

Science.gov (United States)

Sidi, Fatimah; Daud, Maslina; Ahmad, Sabariah; Zainuddin, Naqliyah; Anneisa Abdullah, Syafiqa; Jabar, Marzanah A.; Suriani Affendey, Lilly; Ishak, Iskandar; Sharef, Nurfadhlina Mohd; Zolkepli, Maslina; Nur Majdina Nordin, Fatin; Amat Sejani, Hashimah; Ramadzan Hairani, Saiful

2017-09-01

Information security has been identified by organizations as part of internal operations that need to be well implemented and protected. This is because each day the organizations face a high probability of increase of threats to their networks and services that will lead to information security issues. Thus, effective information security management is required in order to protect their information assets. Threat profiling is a method that can be used by an organization to address the security challenges. Threat profiling allows analysts to understand and organize intelligent information related to threat groups. This paper presents a comparative analysis that was conducted to study the existing threat profiling models. It was found that existing threat models were constructed based on specific objectives, thus each model is limited to only certain components or factors such as assets, threat sources, countermeasures, threat agents, threat outcomes and threat actors. It is suggested that threat profiling can be improved by the combination of components found in each existing threat profiling model/framework. The proposed model can be used by an organization in executing a proactive approach to incident management.

From nestling calls to fledgling silence: adaptive timing of change in response to aerial alarm calls.

Science.gov (United States)

Magrath, Robert D; Platzen, Dirk; Kondo, Junko

2006-09-22

Young birds and mammals are extremely vulnerable to predators and so should benefit from responding to parental alarm calls warning of danger. However, young often respond differently from adults. This difference may reflect: (i) an imperfect stage in the gradual development of adult behaviour or (ii) an adaptation to different vulnerability. Altricial birds provide an excellent model to test for adaptive changes with age in response to alarm calls, because fledglings are vulnerable to a different range of predators than nestlings. For example, a flying hawk is irrelevant to a nestling in a enclosed nest, but is dangerous to that individual once it has left the nest, so we predict that young develop a response to aerial alarm calls to coincide with fledging. Supporting our prediction, recently fledged white-browed scrubwrens, Sericornis frontalis, fell silent immediately after playback of their parents' aerial alarm call, whereas nestlings continued to calling despite hearing the playback. Young scrubwrens are therefore exquisitely adapted to the changing risks faced during development.

MODELLING AND VIBRATION ANALYSIS OF A ROAD PROFILE MEASURING SYSTEM

Directory of Open Access Journals (Sweden)

C. B. Patel

2010-06-01

Full Text Available During a vehicle development program, load data representing severe customer usage is required. The dilemma faced by a design engineer during the design process is that during the initial stage, only predicted loads estimated from historical targets are available, whereas the actual loads are available only at the fag end of the process. At the same time, changes required, if any, are easier and inexpensive during the initial stages of the design process whereas they are extremely costly in the latter stages of the process. The use of road profiles and vehicle models to predict the load acting on the whole vehicle is currently being researched. This work hinges on the ability to accurately measure road profiles. The objective of the work is to develop an algorithm, using MATLAB Simulink software, to convert the input signals into measured road profile. The algorithm is checked by the MATLAB Simulink 4 degrees of freedom half car model. To make the whole Simulink model more realistic, accelerometer and laser sensor properties are introduced. The present work contains the simulation of the mentioned algorithm with a half car model and studies the results in distance, time, and the frequency domain.

Line profile studies of hydrodynamical models of cometary compact H II regions

International Nuclear Information System (INIS)

Zhu, Feng-Yao; Zhu, Qing-Feng

2015-01-01

We simulate the evolution of cometary H II regions based on several champagne flow models and bow shock models, and calculate the profiles of the [Ne II] fine-structure line at 12.81 μm, the H30α recombination line and the [Ne III] fine-structure line at 15.55 μm for these models at different inclinations of 0°, 30° and 60°. We find that the profiles in the bow shock models are generally different from those in the champagne flow models, but the profiles in the bow shock models with lower stellar velocity (≤ 5 km s −1 ) are similar to those in the champagne flow models. In champagne flow models, both the velocity of peak flux and the flux weighted central velocities of all three lines point outward from molecular clouds. In bow shock models, the directions of these velocities depend on the speed of stars. The central velocities of these lines are consistent with the stellar motion in the high stellar speed cases, but they are opposite directions from the stellar motion in the low speed cases. We notice that the line profiles from the slit along the symmetrical axis of the projected 2D image of these models are useful for distinguishing bow shock models from champagne flow models. It is also confirmed by the calculation that the flux weighted central velocity and the line luminosity of the [Ne III] line can be estimated from the [Ne II] line and the H30α line. (paper)

Velocity profiles in idealized model of human respiratory tract

Science.gov (United States)

Elcner, J.; Jedelsky, J.; Lizal, F.; Jicha, M.

2013-04-01

This article deals with numerical simulation focused on velocity profiles in idealized model of human upper airways during steady inspiration. Three r gimes of breathing were investigated: Resting condition, Deep breathing and Light activity which correspond to most common regimes used for experiments and simulations. Calculation was validated with experimental data given by Phase Doppler Anemometry performed on the model with same geometry. This comparison was made in multiple points which form one cross-section in trachea near first bifurcation of bronchial tree. Development of velocity profile in trachea during steady inspiration was discussed with respect for common phenomenon formed in trachea and for future research of transport of aerosol particles in human respiratory tract.

Velocity profiles in idealized model of human respiratory tract

Directory of Open Access Journals (Sweden)

Jicha M.

2013-04-01

Full Text Available This article deals with numerical simulation focused on velocity profiles in idealized model of human upper airways during steady inspiration. Three r gimes of breathing were investigated: Resting condition, Deep breathing and Light activity which correspond to most common regimes used for experiments and simulations. Calculation was validated with experimental data given by Phase Doppler Anemometry performed on the model with same geometry. This comparison was made in multiple points which form one cross-section in trachea near first bifurcation of bronchial tree. Development of velocity profile in trachea during steady inspiration was discussed with respect for common phenomenon formed in trachea and for future research of transport of aerosol particles in human respiratory tract.

Restricting the marketing of foods and non-alcoholic beverages to children in South Africa: are all nutrient profiling models the same?

Science.gov (United States)

Wicks, Mariaan; Wright, Hattie; Wentzel-Viljoen, Edelweiss

2016-12-01

The WHO has called for governments to improve children's food environment by implementing restrictions on the marketing of 'unhealthy' foods to children. Nutrient profiling (NP) models are used to define 'unhealthy' foods and support child-directed food marketing regulations. The aim of the present study was to assess the suitability of the South African NP model (SANPM), developed and validated for health claim regulations, for child-directed food marketing regulations. The SANPM was compared with four NP models specifically developed for such regulations. A representative list of 197 foods was compiled by including all foods advertised on South African free-to-air television channels in 2014 and foods commonly consumed by South African children. The nutritional information of the foods was sourced from food packaging, company websites and a food composition table. Each individual food was classified by each of the five NP models. The percentage of foods that would be allowed according to the different NP models ranged from 6 to 45 %; the models also varied considerably with regard to the type of foods allowed for marketing to children. The majority of the pairwise comparisons between the NP models yielded κ statistics >0·4, indicating a moderate agreement between the models. An almost perfect pairwise agreement (κ=0·948) existed between the SANPM and the UK Food Standards Agency model (United Kingdom Office of Communication nutrient profiling model), a model extensively tested and validated for such regulations. The SANPM is considered appropriate for child-directed food marketing regulations in South Africa.

Market segment derivation and profiling via a finite mixture model framework

NARCIS (Netherlands)

Wedel, M; Desarbo, WS

The Marketing literature has shown how difficult it is to profile market segments derived with finite mixture models. especially using traditional descriptor variables (e.g., demographics). Such profiling is critical for the proper implementation of segmentation strategy. we propose a new finite

Chemical, physical, profile and other oceanographic data collected aboard the Brooks McCall in the Gulf of Mexico from 2010-05-18 to 2010-05-22 in response to the Deepwater Horizon Oil Spill event (NODC Accession 0069044)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Chemical, physical, profile, laboratory analysis, tows and underway oceanographic data were collected aboard the Brooks McCall in the Gulf of Mexico from 2010-05-18...

Evaluation of a Postdischarge Call System Using the Logic Model.

Science.gov (United States)

Frye, Timothy C; Poe, Terri L; Wilson, Marisa L; Milligan, Gary

2018-02-01

This mixed-method study was conducted to evaluate a postdischarge call program for congestive heart failure patients at a major teaching hospital in the southeastern United States. The program was implemented based on the premise that it would improve patient outcomes and overall quality of life, but it had never been evaluated for effectiveness. The Logic Model was used to evaluate the input of key staff members to determine whether the outputs and results of the program matched the expectations of the organization. Interviews, online surveys, reviews of existing patient outcome data, and reviews of publicly available program marketing materials were used to ascertain current program output. After analyzing both qualitative and quantitative data from the evaluation, recommendations were made to the organization to improve the effectiveness of the program.

Investigation and modeling of CPL mask profiles using OCD

Science.gov (United States)

Chen, Hsuan-Chen; Lin, Ren-Hao; Chen, Chien-Cheng; Huang, Cheng-Hsuan; Lien, Ta-Cheng; Chen, Chia-Jen; Lee, Gaston; Lee, Hsin-Chang; Yen, Anthony

2016-05-01

Mask profile of chromeless phase-shifting lithography (CPL) defined by OCD has been investigated. In CPL masks, unbalanced bombardments caused by different ion accelerations lead to the formation of micro-notch structures. A better understanding of micro-notch structures is essential for quality gating of mask processes to improve of CPL mask profiles. By measuring 12 of 16 elements of Mueller matrix, we are able to set up a model to simulate the depth of micro-notch structure profile which shows good correlation with TEM images. Moreover, values of CD, quartz etching depth and side wall angle acquired by OCD are presented and compared with those obtained by SEM, TEM and AFM, respectively.

Bifactor Approach to Modeling Multidimensionality of Physical Self-Perception Profile

Science.gov (United States)

Chung, ChihMing; Liao, Xiaolan; Song, Hairong; Lee, Taehun

2016-01-01

The multi-dimensionality of Physical Self-Perception Profile (PSPP) has been acknowledged by the use of correlated-factor model and second-order model. In this study, the authors critically endorse the bifactor model, as a substitute to address the multi-dimensionality of PSPP. To cross-validate the models, analyses are conducted first in…

Turchin's Relation for Call-by-Name Computations: A Formal Approach

OpenAIRE

Antonina Nepeivoda

2016-01-01

Supercompilation is a program transformation technique that was first described by V. F. Turchin in the 1970s. In supercompilation, Turchin's relation as a similarity relation on call-stack configurations is used both for call-by-value and call-by-name semantics to terminate unfolding of the program being transformed. In this paper, we give a formal grammar model of call-by-name stack behaviour. We classify the model in terms of the Chomsky hierarchy and then formally prove that Turchin's rel...

Too close to call

DEFF Research Database (Denmark)

Kurrild-Klitgaard, Peter

2012-01-01

a number of other frequent explanations and is found to be quite robust. When augmented with approval ratings for incumbent presidents, the explanatory power increases to 83 pct. and only incorrectly calls one of the last 15 US presidential elections. Applied to the 2012 election as a forecasting model...

Integrated modeling of temperature profiles in L-mode tokamak discharges

Energy Technology Data Exchange (ETDEWEB)

Rafiq, T.; Kritz, A. H.; Tangri, V. [Department of Physics, Lehigh University, Bethlehem, Pennsylvania 18015 (United States); Pankin, A. Y. [Tech-X Corporation, Boulder, Colorado 80303 (United States); Voitsekhovitch, I. [CCFE, Culham Science Centre, Abingdon, Oxon OX14 3DB (United Kingdom); Budny, R. V. [Princeton Plasma Physics Laboratory, Princeton, New Jersey 08543 (United States)

2014-12-15

Simulations of doublet III-D, the joint European tokamak, and the tokamak fusion test reactor L-mode tokamak plasmas are carried out using the PTRANSP predictive integrated modeling code. The simulation and experimental temperature profiles are compared. The time evolved temperature profiles are computed utilizing the Multi-Mode anomalous transport model version 7.1 (MMM7.1) which includes transport associated with drift-resistive-inertial ballooning modes (the DRIBM model [T. Rafiq et al., Phys. Plasmas 17, 082511 (2010)]). The tokamak discharges considered involved a broad range of conditions including scans over gyroradius, ITER like current ramp-up, with and without neon impurity injection, collisionality, and low and high plasma current. The comparison of simulation and experimental temperature profiles for the discharges considered is shown for the radial range from the magnetic axis to the last closed flux surface. The regions where various modes in the Multi-Mode model contribute to transport are illustrated. In the simulations carried out using the MMM7.1 model it is found that: The drift-resistive-inertial ballooning modes contribute to the anomalous transport primarily near the edge of the plasma; transport associated with the ion temperature gradient and trapped electron modes contribute in the core region but decrease in the region of the plasma boundary; and neoclassical ion thermal transport contributes mainly near the center of the discharge.

Call centers with a postponed callback offer

NARCIS (Netherlands)

B. Legros (Benjamin); S. Ding (Sihan); R.D. van der Mei (Rob); O. Jouini (Oualid)

2017-01-01

textabstractWe study a call center model with a postponed callback option. A customer at the head of the queue whose elapsed waiting time achieves a given threshold receives a voice message mentioning the option to be called back later. This callback option differs from the traditional ones found in

Consumer concerns about paracetamol: a retrospective analysis of a medicines call centre.

Science.gov (United States)

Lau, Stephanie M; McGuire, Treasure M; van Driel, Mieke L

2016-06-08

To identify consumer information needs about paracetamol, the most commonly used analgesic and antipyretic worldwide. Retrospective analysis of medicines questions from the public. Australian consumer medicines call centre. Callers to National Prescribing Service Medicines Line between September 2002 and June 2010 (n=123 217). Enquiry profile: demographics, enquiry type and concurrent medicines included in paracetamol calls; question themes derived from subset of call narratives. Paracetamol comprised part of the enquiry in 5.2% of calls (n=6367). The caller age distribution for paracetamol calls was skewed towards a younger cohort, with 45.2% made by those aged 25-44 vs 37.5% in 'rest of calls'. Significantly more paracetamol-related calls were made for a child (23.7%) compared with 'rest of calls' (12.7%, pConsumers have many concerns about the use of paracetamol that may be under-recognised by healthcare providers, with the nature of enquiries differing across life stages. These concerns are not adequately addressed by available consumer information. Improving access to targeted information about paracetamol would promote the safe and effective use of this common medicine. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Non-LTE profiles of the Al I autoionization lines. [for solar model atmospheres

Science.gov (United States)

Finn, G. D.; Jefferies, J. T.

1974-01-01

A non-LTE formulation is given for the transfer of radiation in the autoionizing lines of neutral aluminum at 1932 and 1936 A through both the Bilderberg and Harvard-Smithsonian model atmospheres. Numerical solutions for the common source function of these lines and their theoretical line profiles are calculated and compared with the corresponding LTE profiles. The results show that the non-LTE profiles provide a better match with the observations. They also indicate that the continuous opacity of the standard solar models should be increased in this wavelength region if the center-limb variations of observed and theoretical profiles of these lines are to be in reasonable agreement.

Chemical, physical, profile and other oceanographic data collected aboard the Brooks McCall in the Gulf of Mexico from 2010-05-07 to 2010-05-12 in response to the Deepwater Horizon Oil Spill event (NODC Accession 0084555)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Chemical, physical, profile, tows and underway oceanographic data were collected aboard the Brooks McCall in the Gulf of Mexico from 2010-05-07 to 2010-05-12 in...

Optimal scheduling in call centers with a callback option

OpenAIRE

Legros , Benjamin; Jouini , Oualid; Koole , Ger

2016-01-01

International audience; We consider a call center model with a callback option, which allows to transform an inbound call into an outbound one. A delayed call, with a long anticipated waiting time, receives the option to be called back. We assume a probabilistic customer reaction to the callback offer (option). The objective of the system manager is to characterize the optimal call scheduling that minimizes the expected waiting and abandonment costs. For the single-server case, we prove that ...

A New Profile Learning Model for Recommendation System based on Machine Learning Technique

Directory of Open Access Journals (Sweden)

Shereen H. Ali

2016-03-01

Full Text Available Recommender systems (RSs have been used to successfully address the information overload problem by providing personalized and targeted recommendations to the end users. RSs are software tools and techniques providing suggestions for items to be of use to a user, hence, they typically apply techniques and methodologies from Data Mining. The main contribution of this paper is to introduce a new user profile learning model to promote the recommendation accuracy of vertical recommendation systems. The proposed profile learning model employs the vertical classifier that has been used in multi classification module of the Intelligent Adaptive Vertical Recommendation (IAVR system to discover the user’s area of interest, and then build the user’s profile accordingly. Experimental results have proven the effectiveness of the proposed profile learning model, which accordingly will promote the recommendation accuracy.

A Mathematical Model for the Exhaust Gas Temperature Profile of a Diesel Engine

Science.gov (United States)

Brito, C. H. G.; Maia, C. B.; Sodré, J. R.

2015-09-01

This work presents a heat transfer model for the exhaust gas of a diesel power generator to determine the gas temperature profile in the exhaust pipe. The numerical methodology to solve the mathematical model was developed using a finite difference method approach for energy equation resolution and determination of temperature profiles considering turbulent fluid flow and variable fluid properties. The simulation was carried out for engine operation under loads from 0 kW to 40 kW. The model was compared with results obtained using the multidimensional Ansys CFX software, which was applied to solve the governor equations of turbulent fluid flow. The results for the temperature profiles in the exhaust pipe show a good proximity between the mathematical model developed and the multidimensional software.

Evaluation of Software Quality to Improve Application Performance Using Mc Call Model

Directory of Open Access Journals (Sweden)

Inda D Lestantri

2018-04-01

Full Text Available The existence of software should have more value to improve the performance of the organization in addition to having the primary function to automate. Before being implemented in an operational environment, software must pass the test gradually to ensure that the software is functioning properly, meeting user needs and providing convenience for users to use it. This test is performed on a web-based application, by taking a test case in an e-SAP application. E-SAP is an application used to monitor teaching and learning activities used by a university in Jakarta. To measure software quality, testing can be done on users randomly. The user samples selected in this test are users with an age range of 18 years old up to 25 years, background information technology. This test was conducted on 30 respondents. This test is done by using Mc Call model. Model of testing Mc Call consists of 11 dimensions are grouped into 3 categories. This paper describes the testing with reference to the category of product operation, which includes 5 dimensions. The dimensions of testing performed include the dimensions of correctness, usability, efficiency, reliability, and integrity. This paper discusses testing on each dimension to measure software quality as an effort to improve performance. The result of research is e-SAP application has good quality with product operation value equal to 85.09%. This indicates that the e-SAP application has a great quality, so this application deserves to be examined in the next stage on the operational environment.

A multi-model analysis of vertical ozone profiles

Directory of Open Access Journals (Sweden)

J. E. Jonson

2010-06-01

Full Text Available A multi-model study of the long-range transport of ozone and its precursors from major anthropogenic source regions was coordinated by the Task Force on Hemispheric Transport of Air Pollution (TF HTAP under the Convention on Long-range Transboundary Air Pollution (LRTAP. Vertical profiles of ozone at 12-h intervals from 2001 are available from twelve of the models contributing to this study and are compared here with observed profiles from ozonesondes. The contributions from each major source region are analysed for selected sondes, and this analysis is supplemented by retroplume calculations using the FLEXPART Lagrangian particle dispersion model to provide insight into the origin of ozone transport events and the cause of differences between the models and observations.

In the boundary layer ozone levels are in general strongly affected by regional sources and sinks. With a considerably longer lifetime in the free troposphere, ozone here is to a much larger extent affected by processes on a larger scale such as intercontinental transport and exchange with the stratosphere. Such individual events are difficult to trace over several days or weeks of transport. This may explain why statistical relationships between models and ozonesonde measurements are far less satisfactory than shown in previous studies for surface measurements at all seasons. The lowest bias between model-calculated ozone profiles and the ozonesonde measurements is seen in the winter and autumn months. Following the increase in photochemical activity in the spring and summer months, the spread in model results increases, and the agreement between ozonesonde measurements and the individual models deteriorates further.

At selected sites calculated contributions to ozone levels in the free troposphere from intercontinental transport are shown. Intercontinental transport is identified based on differences in model calculations with unperturbed emissions and

CPHmodels-3.0--remote homology modeling using structure-guided sequence profiles

DEFF Research Database (Denmark)

Nielsen, Morten; Lundegaard, Claus; Lund, Ole

2010-01-01

CPHmodels-3.0 is a web server predicting protein 3D structure by use of single template homology modeling. The server employs a hybrid of the scoring functions of CPHmodels-2.0 and a novel remote homology-modeling algorithm. A query sequence is first attempted modeled using the fast CPHmodels-2.......0 profile-profile scoring function suitable for close homology modeling. The new computational costly remote homology-modeling algorithm is only engaged provided that no suitable PDB template is identified in the initial search. CPHmodels-3.0 was benchmarked in the CASP8 competition and produced models.......3 A. These performance values place the CPHmodels-3.0 method in the group of high performing 3D prediction tools. Beside its accuracy, one of the important features of the method is its speed. For most queries, the response time of the server is...

RASS sound speed profile (SSP) measurements for use in outdoor sound propagation models

Energy Technology Data Exchange (ETDEWEB)

Bradley, S G [Physics Department, University of Auckland (New Zealand); Huenerbein, S v; Waddington, D [Research Institute for the Built and Human Environment, University of Salford (United Kingdom)], E-mail: s.vonhunerbein@salford.ac.uk

2008-05-01

The performance of outdoor sound propagation models depends to a great extent on meteorological input parameters. In an effort to improve speed and accuracy, model output synthetic sound speed profiles (SSP) are commonly used depending on meteorological classification schemes. In order to use SSP measured by RASS in outdoor sound propagation models, the complex profiles need to be simplified. In this paper we extend an investigation on the spatial and temporal characteristics of the meteorological data set required to yield adequate comparisons between models and field measurements, so that the models can be fairly judged. Vertical SSP from RASS, SODAR wind profiles as well as mast wind and temperature data from a flat terrain site and measured over a period of several months are used to evaluate applicability of the logarithmic approximation for a stability classification scheme proposed by the HARMONOISE working group.

RASS sound speed profile (SSP) measurements for use in outdoor sound propagation models

International Nuclear Information System (INIS)

Bradley, S G; Huenerbein, S v; Waddington, D

2008-01-01

The performance of outdoor sound propagation models depends to a great extent on meteorological input parameters. In an effort to improve speed and accuracy, model output synthetic sound speed profiles (SSP) are commonly used depending on meteorological classification schemes. In order to use SSP measured by RASS in outdoor sound propagation models, the complex profiles need to be simplified. In this paper we extend an investigation on the spatial and temporal characteristics of the meteorological data set required to yield adequate comparisons between models and field measurements, so that the models can be fairly judged. Vertical SSP from RASS, SODAR wind profiles as well as mast wind and temperature data from a flat terrain site and measured over a period of several months are used to evaluate applicability of the logarithmic approximation for a stability classification scheme proposed by the HARMONOISE working group

Topside electron density: comparison of experimental and IRI model profiles during low solar activity period

International Nuclear Information System (INIS)

Alazo, K.; Coisson, P.; Radicella, S.M.

2003-01-01

The pattern of the topside electron density profiles is not yet very well represented by the IRI model. In this work the topside profiles obtained by the ISIS-2 satellite during low solar activity conditions are compared to those modeled by IRI. We take the quantitative parameter ε to measure the deviation of the model from the observed profiles. The results showed that the IRI overestimation of the topside profile is higher for low dip latitudes. The dispersion of the epsilon values is from 40 to 140%, more in equinoctial months and some lower for Winter. The best modeling is about 20% to 40% in middle and high latitudes of the North Hemisphere. (author)

Atmospheric turbulence profiling with unknown power spectral density

Science.gov (United States)

Helin, Tapio; Kindermann, Stefan; Lehtonen, Jonatan; Ramlau, Ronny

2018-04-01

Adaptive optics (AO) is a technology in modern ground-based optical telescopes to compensate for the wavefront distortions caused by atmospheric turbulence. One method that allows to retrieve information about the atmosphere from telescope data is so-called SLODAR, where the atmospheric turbulence profile is estimated based on correlation data of Shack-Hartmann wavefront measurements. This approach relies on a layered Kolmogorov turbulence model. In this article, we propose a novel extension of the SLODAR concept by including a general non-Kolmogorov turbulence layer close to the ground with an unknown power spectral density. We prove that the joint estimation problem of the turbulence profile above ground simultaneously with the unknown power spectral density at the ground is ill-posed and propose three numerical reconstruction methods. We demonstrate by numerical simulations that our methods lead to substantial improvements in the turbulence profile reconstruction compared to the standard SLODAR-type approach. Also, our methods can accurately locate local perturbations in non-Kolmogorov power spectral densities.

Modeling of welded bead profile for rapid prototyping by robotic MAG welding

Institute of Scientific and Technical Information of China (English)

CAO Yong; ZHU Sheng; WANG Tao; WANG Wanglong

2009-01-01

As a deposition technology, robotic metal active gas(MAG) welding has shown new promise for rapid prototyping (RP) of metallic parts. During the process of metal forming using robotic MAG welding, sectional profile of single-pass welded bead is critical to formed accuracy and quality of metal pans. In this paper, the experiments of single-pass welded bead for rapid prototyping using robotic MAG welding were carried out. The effect of some edge detectors on the cross-sectional edge of welded bead was discussed and curve fitting was applied using leat square fitting. Consequently, the mathematical model of welded bead profile was developed. The experimental results show that good shape could be obtained under suitable welding parameters. Canny operawr is suitable to edge detection of welded bead profile, and the mathematical model of welded bead profile developed is approximately parabola.

Blended call center with idling times during the call service

NARCIS (Netherlands)

Legros, Benjamin; Jouini, Oualid; Koole, Ger

We consider a blended call center with calls arriving over time and an infinitely backlogged amount of outbound jobs. Inbound calls have a non-preemptive priority over outbound jobs. The inbound call service is characterized by three successive stages where the second one is a break; i.e., there is

Using scale heights derived from bottomside ionograms for modelling the IRI topside profile

Directory of Open Access Journals (Sweden)

B. W. Reinisch

2004-01-01

Full Text Available Groundbased ionograms measure the Chapman scale height HT at the F2-layer peak that is used to construct the topside profile. After a brief review of the topside model extrapolation technique, comparisons are presented between the modeled profiles with incoherent scatter radar and satellite measurements for the mid latitude and equatorial ionosphere. The total electron content TEC, derived from measurements on satellite beacon signals, is compared with the height-integrated profiles ITEC from the ionograms. Good agreement is found with the ISR profiles and with results using the low altitude TOPEX satellite. The TEC values derived from GPS signal analysis are systematically larger than ITEC. It is suggested to use HT , routinely measured by a large number of Digisondes around the globe, for the construction of the IRI topside electron density profile.

N-GrAM: New Groningen Author-profiling Model

NARCIS (Netherlands)

Basile, Angelo; Dwyer, Gareth; Medvedeva, Masha; Rawee, Josine; Haagsma, Hessel; Nissim, Malvina

2017-01-01

We describe our participation in the PAN 2017 shared task on Author Profiling, identifying authors’ gender and language variety for English, Spanish, Arabic and Portuguese. We describe both the final, submitted system, and a series of negative results. Our aim was to create a single model for both

Exploring personalized searches using tag-based user profiles and resource profiles in folksonomy.

Science.gov (United States)

Cai, Yi; Li, Qing; Xie, Haoran; Min, Huaqin

2014-10-01

With the increase in resource-sharing websites such as YouTube and Flickr, many shared resources have arisen on the Web. Personalized searches have become more important and challenging since users demand higher retrieval quality. To achieve this goal, personalized searches need to take users' personalized profiles and information needs into consideration. Collaborative tagging (also known as folksonomy) systems allow users to annotate resources with their own tags, which provides a simple but powerful way for organizing, retrieving and sharing different types of social resources. In this article, we examine the limitations of previous tag-based personalized searches. To handle these limitations, we propose a new method to model user profiles and resource profiles in collaborative tagging systems. We use a normalized term frequency to indicate the preference degree of a user on a tag. A novel search method using such profiles of users and resources is proposed to facilitate the desired personalization in resource searches. In our framework, instead of the keyword matching or similarity measurement used in previous works, the relevance measurement between a resource and a user query (termed the query relevance) is treated as a fuzzy satisfaction problem of a user's query requirements. We implement a prototype system called the Folksonomy-based Multimedia Retrieval System (FMRS). Experiments using the FMRS data set and the MovieLens data set show that our proposed method outperforms baseline methods. Copyright © 2014 Elsevier Ltd. All rights reserved.

Chemical, physical, profile and laboratory analysis oceanographic data collected aboard the Brooks McCall in the Gulf of Mexico from 2010-07-04 to 2010-07-08 in response to the Deepwater Horizon Oil Spill event (NODC Accession 0069051)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Chemical, physical, profile and laboratory analysis oceanographic data were collected aboard the Brooks McCall in the Gulf of Mexico from 2010-07-04 to 2010-07-08 in...

Chemical, physical, profile and laboratory analysis oceanographic data collected aboard the Brooks McCall in the Gulf of Mexico from 2010-05-30 to 2010-06-02 in response to the Deepwater Horizon Oil Spill event (NODC Accession 0069046)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Chemical, physical, profile and laboratory analysis oceanographic data were collected aboard the Brooks McCall in the Gulf of Mexico from 2010-05-30 to 2010-06-02 in...

Chemical, physical, profile and laboratory analysis oceanographic data collected aboard the Brooks McCall in the Gulf of Mexico from 2010-08-03 to 2010-08-07 in response to the Deepwater Horizon Oil Spill event (NODC Accession 0069055)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Chemical, physical, profile and laboratory analysis oceanographic data were collected aboard the Brooks McCall in the Gulf of Mexico from 2010-08-03 to 2010-08-07 in...

Chemical, physical, profile and laboratory analysis oceanographic data collected aboard the Brooks McCall in the Gulf of Mexico from 2010-08-21 to 2010-08-25 in response to the Deepwater Horizon Oil Spill event (NODC Accession 0069090)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Chemical, physical, profile and laboratory analysis oceanographic data were collected aboard the Brooks McCall in the Gulf of Mexico from 2010-08-21 to 2010-08-25 in...

Chemical, physical, profile and laboratory analysis oceanographic data collected aboard the Brooks McCall in the Gulf of Mexico from 2010-07-16 to 2010-07-20 in response to the Deepwater Horizon Oil Spill event (NODC Accession 0069053)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Chemical, physical, profile and laboratory analysis oceanographic data were collected aboard the Brooks McCall in the Gulf of Mexico from 2010-07-16 to 2010-07-20 in...

Chemical, physical, profile and laboratory analysis oceanographic data collected aboard the Brooks McCall in the Gulf of Mexico from 2010-06-22 to 2010-06-26 in response to the Deepwater Horizon Oil Spill event (NODC Accession 0069050)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Chemical, physical, profile and laboratory analysis oceanographic data were collected aboard the Brooks McCall in the Gulf of Mexico from 2010-06-22 to 2010-06-26 in...

Chemical, physical, profile and laboratory analysis oceanographic data collected aboard the Brooks McCall in the Gulf of Mexico from 2010-08-15 to 2010-08-19 in response to the Deepwater Horizon Oil Spill event (NODC Accession 0069057)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Chemical, physical, profile and laboratory analysis oceanographic data were collected aboard the Brooks McCall in the Gulf of Mexico from 2010-08-15 to 2010-08-19 in...

Chemical, physical, profile and laboratory analysis oceanographic data collected aboard the Brooks McCall in the Gulf of Mexico from 2010-08-09 to 2010-08-12 in response to the Deepwater Horizon Oil Spill event (NODC Accession 0069056)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Chemical, physical, profile and laboratory analysis oceanographic data were collected aboard the Brooks McCall in the Gulf of Mexico from 2010-08-09 to 2010-08-12 in...

Chemical, physical, profile and laboratory analysis oceanographic data collected aboard the Brooks McCall in the Gulf of Mexico from 2010-07-28 to 2010-08-01 in response to the Deepwater Horizon Oil Spill event (NODC Accession 0069054)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Chemical, physical, profile and laboratory analysis oceanographic data were collected aboard the Brooks McCall in the Gulf of Mexico from 2010-07-28 to 2010-08-01 in...

Chemical, physical, profile and laboratory analysis oceanographic data collected aboard the Brooks McCall in the Gulf of Mexico from 2010-05-23 to 2010-05-25 in response to the Deepwater Horizon Oil Spill event (NODC Accession 0069045)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Chemical, physical, profile and laboratory analysis oceanographic data were collected aboard the Brooks McCall in the Gulf of Mexico from 2010-05-23 to 2010-05-25 in...

Chemical, physical, profile and laboratory analysis oceanographic data collected aboard the Brooks McCall in the Gulf of Mexico from 2010-06-10 to 2010-06-14 in response to the Deepwater Horizon Oil Spill event (NODC Accession 0069048)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Chemical, physical, profile and laboratory analysis oceanographic data were collected aboard the Brooks McCall in the Gulf of Mexico from 2010-06-10 to 2010-06-14 in...

Chemical, physical, profile and laboratory analysis oceanographic data collected aboard the Brooks McCall in the Gulf of Mexico from 2010-09-07 to 2010-09-11 in response to the Deepwater Horizon Oil Spill event (NODC Accession 0074853)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Chemical, physical, profile and laboratory analysis oceanographic data were collected aboard the Brooks McCall in the Gulf of Mexico from 2010-09-07 to 2010-09-11 in...

Chemical, physical, profile and laboratory analysis oceanographic data collected aboard the Brooks McCall in the Gulf of Mexico from 2010-06-16 to 2010-06-20 in response to the Deepwater Horizon Oil Spill event (NODC Accession 0069049)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Chemical, physical, profile and laboratory analysis oceanographic data were collected aboard the Brooks McCall in the Gulf of Mexico from 2010-06-16 to 2010-06-20 in...

Chemical, physical, profile and laboratory analysis oceanographic data collected aboard the Brooks McCall in the Gulf of Mexico from 2010-05-14 to 2010-05-18 in response to the Deepwater Horizon Oil Spill event (NODC Accession 0074372)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Chemical, physical, profile and laboratory analysis oceanographic data were collected aboard the Brooks McCall in the Gulf of Mexico from 2010-05-14 to 2010-05-18 in...

Chemical, physical, profile and laboratory analysis oceanographic data collected aboard the Brooks McCall in the Gulf of Mexico from 2010-07-10 to 2010-07-14 in response to the Deepwater Horizon Oil Spill event (NODC Accession 0069052)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Chemical, physical, profile and laboratory analysis oceanographic data were collected aboard the Brooks McCall in the Gulf of Mexico from 2010-07-10 to 2010-07-14 in...

Chemical, physical, profile and laboratory analysis oceanographic data collected aboard the Brooks McCall in the Gulf of Mexico from 2010-06-04 to 2010-06-08 in response to the Deepwater Horizon Oil Spill event (NODC Accession 0069047)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Chemical, physical, profile and laboratory analysis oceanographic data were collected aboard the Brooks McCall in the Gulf of Mexico from 2010-06-04 to 2010-06-08 in...

Profiling the biological activity of oxide nanomaterials with mechanistic models

NARCIS (Netherlands)

Burello, E.

2013-01-01

In this study we present three mechanistic models for profiling the potential biological and toxicological effects of oxide nanomaterials. The models attempt to describe the reactivity, protein adsorption and membrane adhesion processes of a large range of oxide materials and are based on properties

Basket call option pricing for CCVG using sparse grids

KAUST Repository

Crocce, Fabian

2016-01-06

The use of processes with jumps to overcome the shortcomings of the classical Black and Scholes when modelling stock prices has became very popular. One of the best-known models is the Common Clock Variance Gamma model (CCVG), introduced by Madan and Seneta in the 1990 [3]. We propose a method to price European basket call options modelled by the CCVG. The method could be extended to other model obtained by the subordination of a multidimensional Brownian motion and to more general options. To simplify the expositions we consider calls under the CCVG.

Basket call option pricing for CCVG using sparse grids

KAUST Repository

Crocce, Fabian; Hä ppö lä , Juho; Iania, Alessandro; Tempone, Raul

2016-01-01

The use of processes with jumps to overcome the shortcomings of the classical Black and Scholes when modelling stock prices has became very popular. One of the best-known models is the Common Clock Variance Gamma model (CCVG), introduced by Madan and Seneta in the 1990 [3]. We propose a method to price European basket call options modelled by the CCVG. The method could be extended to other model obtained by the subordination of a multidimensional Brownian motion and to more general options. To simplify the expositions we consider calls under the CCVG.

EMS call center models with and without function differentiation: a comparison

NARCIS (Netherlands)

van Buuren, M.; Kommer, G.J.; van der Mei, R.D.; Bhulai, Sandjai

2017-01-01

In pre-hospital health care the call center plays an important role in the coordination of emergency medical services (EMS). An EMS call center handles inbound requests for EMS and dispatches an ambulance if necessary. The time needed for triage and dispatch is part of the total response time to the

High resolution measurements and modeling of auroral hydrogen emission line profiles

Directory of Open Access Journals (Sweden)

B. S. Lanchester

Full Text Available Measurements in the visible wavelength range at high spectral resolution (1.3 Å have been made at Longyearbyen, Svalbard (15.8 E,78.2 N during an interval of intense proton precipitation. The shape and Doppler shift of hydrogen Balmer beta line profiles have been compared with model line profiles, using as input ion energy spectra from almost coincident passes of the FAST and DMSP spacecraft. The comparison shows that the simulation contains the important physical processes that produce the profiles, and confirms that measured changes in the shape and peak wave-length of the hydrogen profiles are the result of changing energy input. This combination of high resolution measurements with modeling provides a method of estimating the incoming energy and changes in flux of precipitating protons over Svalbard, for given energy and pitch-angle distributions. Whereas for electron precipitation, information on the incident particles is derived from brightness and brightness ratios which require at least two spectral windows, for proton precipitation the Doppler profile of resulting hydrogen emission is directly related to the energy and energy flux of the incident energetic protons and can be used to gather information about the source region. As well as the expected Doppler shift to shorter wavelengths, the measured profiles have a significant red-shifted component, the result of upward flowing emitting hydrogen atoms.

Key words. Ionosphere (auroral ionosphere; particle precipitation – Magnetospheric physics (auroral phenomena

High resolution measurements and modeling of auroral hydrogen emission line profiles

Directory of Open Access Journals (Sweden)

B. S. Lanchester

2003-07-01

Full Text Available Measurements in the visible wavelength range at high spectral resolution (1.3 Å have been made at Longyearbyen, Svalbard (15.8 E,78.2 N during an interval of intense proton precipitation. The shape and Doppler shift of hydrogen Balmer beta line profiles have been compared with model line profiles, using as input ion energy spectra from almost coincident passes of the FAST and DMSP spacecraft. The comparison shows that the simulation contains the important physical processes that produce the profiles, and confirms that measured changes in the shape and peak wave-length of the hydrogen profiles are the result of changing energy input. This combination of high resolution measurements with modeling provides a method of estimating the incoming energy and changes in flux of precipitating protons over Svalbard, for given energy and pitch-angle distributions. Whereas for electron precipitation, information on the incident particles is derived from brightness and brightness ratios which require at least two spectral windows, for proton precipitation the Doppler profile of resulting hydrogen emission is directly related to the energy and energy flux of the incident energetic protons and can be used to gather information about the source region. As well as the expected Doppler shift to shorter wavelengths, the measured profiles have a significant red-shifted component, the result of upward flowing emitting hydrogen atoms.Key words. Ionosphere (auroral ionosphere; particle precipitation – Magnetospheric physics (auroral phenomena

Profiling Patients’ Healthcare Needs to Support Integrated, Person-Centered Models for Long-Term Disease Management (Profile: Research Design

Directory of Open Access Journals (Sweden)

Arianne MJ Elissen

2016-04-01

Full Text Available Background: This article presents the design of PROFILe, a study investigating which (biomedical and non-(biomedical patient characteristics should guide more tailored chronic care. Based on this insight, the project aims to develop and validate ‘patient profiles’ that can be used in practice to determine optimal treatment strategies for subgroups of chronically ill with similar healthcare needs and preferences. Methods/Design: PROFILe is a practice-based research comprising four phases. The project focuses on patients with type 2 diabetes. During the first study phase, patient profiles are drafted based on a systematic literature research, latent class growth modeling, and expert collaboration. In phase 2, the profiles are validated from a clinical, patient-related and statistical perspective. Phase 3 involves a discrete choice experiment to gain insight into the patient preferences that exist per profile. In phase 4, the results from all analyses are integrated and recommendations formulated on which patient characteristics should guide tailored chronic care. Discussion: PROFILe is an innovative study which uses a uniquely holistic approach to assess the healthcare needs and preferences of chronically ill. The patient profiles resulting from this project must be tested in practice to investigate the effects of tailored management on patient experience, population health and costs.

The job demands-resources model of work engagement in South African call centres

OpenAIRE

Yolandi Janse van Rensburg; Billy Boonzaier; Michèle Boonzaier

2013-01-01

Orientation: A ‘sacrificial human resource strategy’ is practised in call centres, resulting in poor employee occupational health. Consequently, questions are posed in terms of the consequences of call centre work and which salient antecedent variables impact the engagement and wellbeing of call centre representatives. Research purpose: Firstly, to gauge the level of employee engagement amongst a sample of call centre representatives in South Africa and, secondly, to track the paths throu...

Inhibitors of calling behavior of Plodia interpunctella.

Science.gov (United States)

Hirashima, Akinori; Shigeta, Yoko; Eiraku, Tomohiko; Kuwano, Eiichi

2003-01-01

Some octopamine agonists were found to suppress the calling behavior of the stored product Indian meal moth, Plodia interpunctella. Compounds were screened using a calling behavior bioassay using female P. interpunctella. Four active derivatives, with inhibitory activity at the nanomolar range, were identified in order of decreasing activity: 2-(1-phenylethylamino)-2-oxazoline > 2-(2-ethyl,6-methylanilino)oxazolidine > 2-(2-methyl benzylamino)-2-thiazoline > 2-(2,6-diethylanilino)thiazolidine. Three-dimensional pharmacophore hypotheses were built from a set of 15 compounds. Among the ten common-featured models generated by the program Catalyst/HipHop, a hypothesis including a hydrogen-bond acceptor lipid, a hydrophobic aromatic and two hydrophobic aliphatic features was considered to be essential for inhibitory activity in the calling behavior. Active compounds mapped well onto all the hydrogen-bond acceptor lipid, hydrophobic aromatic and hydrophobic aliphatic features of the hypothesis. On the other hand, less active compounds were shown not to achieve the energetically favorable conformation that is found in the active molecules in order to fit the 3D common-feature pharmacophore models. The present studies demonstrate that inhibition of calling behavior is via an octopamine receptor.

Inhibitors of calling behavior of Plodia interpunctella

Directory of Open Access Journals (Sweden)

Akinori Hirashima

2003-01-01

Full Text Available Some octopamine agonists were found to suppress the calling behavior of the stored product Indian meal moth, Plodia interpunctella. Compounds were screened using a calling behavior bioassay using female P. interpunctella. Four active derivatives, with inhibitory activity at the nanomolar range, were identified in order of decreasing activity: 2-(1-phenylethylamino-2-oxazoline > 2-(2-ethyl,6-methylanilinooxazolidine > 2-(2-methyl benzylamino-2-thiazoline > 2-(2,6-diethylanilinothiazolidine. Three-dimensional pharmacophore hypotheses were built from a set of 15 compounds. Among the ten common-featured models generated by the program Catalyst/HipHop, a hypothesis including a hydrogen-bond acceptor lipid, a hydrophobic aromatic and two hydrophobic aliphatic features was considered to be essential for inhibitory activity in the calling behavior. Active compounds mapped well onto all the hydrogen-bond acceptor lipid, hydrophobic aromatic and hydrophobic aliphatic features of the hypothesis. On the other hand, less active compounds were shown not to achieve the energetically favorable conformation that is found in the active molecules in order to fit the 3D common-feature pharmacophore models. The present studies demonstrate that inhibition of calling behavior is via an octopamine receptor.

The ability of current micro-velocity models to represent center-limb line profiles

International Nuclear Information System (INIS)

Evans, J.C.; Testerman, L.

1975-01-01

Results are presented on the ability of microturbulences, LTE line formation and a homogeneous thermal model to realistically represent the center-limb variation of temporally and spacially averaged solar line profiles. Three somewhat similar semi-empirical thermal models have been used in combination with five current microturbulence models which cover the gamut of homogeneous-isotropic to nonhomogeneous-anisotropic. From high resolution photoelectric data for (lambdalambda 5000-6000 at five μ-values(1,0.63,0.4,0.25,0.16) obtained at KPNO, were selected 17 Fe I and 5 Fe II line profiles to be unblended and symmetrized for study. An iterative scheme has been developed to calculate theoretical profiles for the various combination of models and compare them to the observed profile using the abundance at each limb position and the magnitude of the pressure broadening at the center of the disc as parameters. It was found that a microturbulence model, for which the radial and tangential components increase into deeper layers with xisub(tan)>xisub(rad), produces a reasonable good center-limb fit for lines less than 100mA. However for lines stronger than 140mA, microturbulence models with no depth dependence produce the best match between theory and observation. Thus there is reason to question the uniqueness of the microturbulence concept. (Auth.)

Vacuum Expectation Value Profiles of the Bulk Scalar Field in the Generalized Randall-Sundrum Model

International Nuclear Information System (INIS)

Moazzen, M.; Tofighi, A.; Farokhtabar, A.

2015-01-01

In the generalized Randall-Sundrum warped brane-world model the cosmological constant induced on the visible brane can be positive or negative. In this paper we investigate profiles of vacuum expectation value of the bulk scalar field under general Dirichlet and Neumann boundary conditions in the generalized warped brane-world model. We show that the VEV profiles generally depend on the value of the brane cosmological constant. We find that the VEV profiles of the bulk scalar field for a visible brane with negative cosmological constant and positive tension are quite distinct from those of Randall-Sundrum model. In addition we show that the VEV profiles for a visible brane with large positive cosmological constant are also different from those of the Randall-Sundrum model. We also verify that Goldberger and Wise mechanism can work under nonzero Dirichlet boundary conditions in the generalized Randall-Sundrum model.

Comparisons of Crosswind Velocity Profile Estimates Used in Fast-Time Wake Vortex Prediction Models

Science.gov (United States)

Pruis, Mathew J.; Delisi, Donald P.; Ahmad, Nashat N.

2011-01-01

Five methods for estimating crosswind profiles used in fast-time wake vortex prediction models are compared in this study. Previous investigations have shown that temporal and spatial variations in the crosswind vertical profile have a large impact on the transport and time evolution of the trailing vortex pair. The most important crosswind parameters are the magnitude of the crosswind and the gradient in the crosswind shear. It is known that pulsed and continuous wave lidar measurements can provide good estimates of the wind profile in the vicinity of airports. In this study comparisons are made between estimates of the crosswind profiles from a priori information on the trajectory of the vortex pair as well as crosswind profiles derived from different sensors and a regional numerical weather prediction model.

Information systems performance evaluation, introducing a two-level technique: Case study call centers

Directory of Open Access Journals (Sweden)

Hesham A. Baraka

2015-03-01

The objective of this paper was to introduce a new technique that can support decision makers in the call centers industry to evaluate, and analyze the performance of call centers. The technique presented is derived from the research done on measuring the success or failure of information systems. Two models are mainly adopted namely: the Delone and Mclean model first introduced in 1992 and the Design Reality Gap model introduced by Heeks in 2002. Two indices are defined to calculate the performance of the call center; the success index and the Gap Index. An evaluation tool has been developed to allow call centers managers to evaluate the performance of their call centers in a systematic analytical approach; the tool was applied on 4 call centers from different areas, simple applications such as food ordering, marketing, and sales, technical support systems, to more real time services such as the example of emergency control systems. Results showed the importance of using information systems models to evaluate complex systems as call centers. The models used allow identifying the dimensions for the call centers that are facing challenges, together with an identification of the individual indicators in these dimensions that are causing the poor performance of the call center.

Charnock's Roughness Length Model and Non-dimensional Wind Profiles Over the Sea

DEFF Research Database (Denmark)

Pena Diaz, Alfredo; Gryning, Sven-Erik

2008-01-01

An analysis tool for the study of wind speed profiles over the water has been developed. The profiles are analysed using a modified dimensionless wind speed and dimensionless height, assuming that the sea surface roughness can be predicted by Charnock's roughness length model. In this form, the r...

Element-specific density profiles in interacting biomembrane models

International Nuclear Information System (INIS)

Schneck, Emanuel; Rodriguez-Loureiro, Ignacio; Bertinetti, Luca; Gochev, Georgi; Marin, Egor; Novikov, Dmitri; Konovalov, Oleg

2017-01-01

Surface interactions involving biomembranes, such as cell–cell interactions or membrane contacts inside cells play important roles in numerous biological processes. Structural insight into the interacting surfaces is a prerequisite to understand the interaction characteristics as well as the underlying physical mechanisms. Here, we work with simplified planar experimental models of membrane surfaces, composed of lipids and lipopolymers. Their interaction is quantified in terms of pressure–distance curves using ellipsometry at controlled dehydrating (interaction) pressures. For selected pressures, their internal structure is investigated by standing-wave x-ray fluorescence (SWXF). This technique yields specific density profiles of the chemical elements P and S belonging to lipid headgroups and polymer chains, as well as counter-ion profiles for charged surfaces. (paper)

Inverse Modeling of Emissions and their Time Profiles

Czech Academy of Sciences Publication Activity Database

Resler, Jaroslav; Eben, Kryštof; Juruš, Pavel; Liczki, Jitka

2010-01-01

Roč. 1, č. 4 (2010), s. 288-295 ISSN 1309-1042 R&D Projects: GA MŽP SP/1A4/107/07 Grant - others:COST(XE) ES0602 Institutional research plan: CEZ:AV0Z10300504 Keywords : 4DVar * inverse modeling * diurnal time profile of emission * CMAQ adjoint * satellite observations Subject RIV: DG - Athmosphere Sciences, Meteorology

Optimal service using Matlab - simulink controlled Queuing system at call centers

Science.gov (United States)

Balaji, N.; Siva, E. P.; Chandrasekaran, A. D.; Tamilazhagan, V.

2018-04-01

This paper presents graphical integrated model based academic research on telephone call centres. This paper introduces an important feature of impatient customers and abandonments in the queue system. However the modern call centre is a complex socio-technical system. Queuing theory has now become a suitable application in the telecom industry to provide better online services. Through this Matlab-simulink multi queuing structured models provide better solutions in complex situations at call centres. Service performance measures analyzed at optimal level through Simulink queuing model.

Conditioning a segmented stem profile model for two diameter measurements

Science.gov (United States)

Raymond L. Czaplewski; Joe P. Mcclure

1988-01-01

The stem profile model of Max and Burkhart (1976) is conditioned for dbh and a second upper stem measurement. This model was applied to a loblolly pine data set using diameter outside bark at 5.3m (i.e., height of 17.3 foot Girard form class) as the second upper stem measurement, and then compared to the original, unconditioned model. Variance of residuals was reduced...

Context Analysis of Customer Requests using a Hybrid Adaptive Neuro Fuzzy Inference System and Hidden Markov Models in the Natural Language Call Routing Problem

Science.gov (United States)

Rustamov, Samir; Mustafayev, Elshan; Clements, Mark A.

2018-04-01

The context analysis of customer requests in a natural language call routing problem is investigated in the paper. One of the most significant problems in natural language call routing is a comprehension of client request. With the aim of finding a solution to this issue, the Hybrid HMM and ANFIS models become a subject to an examination. Combining different types of models (ANFIS and HMM) can prevent misunderstanding by the system for identification of user intention in dialogue system. Based on these models, the hybrid system may be employed in various language and call routing domains due to nonusage of lexical or syntactic analysis in classification process.

Context Analysis of Customer Requests using a Hybrid Adaptive Neuro Fuzzy Inference System and Hidden Markov Models in the Natural Language Call Routing Problem

Directory of Open Access Journals (Sweden)

Rustamov Samir

2018-04-01

Full Text Available The context analysis of customer requests in a natural language call routing problem is investigated in the paper. One of the most significant problems in natural language call routing is a comprehension of client request. With the aim of finding a solution to this issue, the Hybrid HMM and ANFIS models become a subject to an examination. Combining different types of models (ANFIS and HMM can prevent misunderstanding by the system for identification of user intention in dialogue system. Based on these models, the hybrid system may be employed in various language and call routing domains due to nonusage of lexical or syntactic analysis in classification process.

Model etch profiles for ion energy distribution functions in an inductively coupled plasma reactor

International Nuclear Information System (INIS)

Chen, W.; Abraham-Shrauner, B.; Woodworth, J.R.

1999-01-01

Rectangular trench profiles are modeled with analytic etch rates determined from measured ion distribution functions. The pattern transfer step for this plasma etch is for trilayer lithography. Argon and chlorine angular ion energy distribution functions measured by a spherical collector ring analyzer are fit to a sum of drifting Maxwellian velocity distribution functions with anisotropic temperatures. The fit of the model ion distribution functions by a simulated annealing optimization procedure converges adequately for only two drifting Maxwellians. The etch rates are proportional to analytic expressions for the ion energy flux. Numerical computation of the etch profiles by integration of the characteristic equations for profile points and connection of the profiles points is efficient. copyright 1999 American Vacuum Society

Dynamic call center routing policies using call waiting and agent idle times

NARCIS (Netherlands)

Chan, W.; Koole, G.M.; L'Ecuyer, P.

2014-01-01

We study call routing policies for call centers with multiple call types and multiple agent groups. We introduce new weight-based routing policies where each pair (call type, agent group) is given a matching priority defined as an affine combination of the longest waiting time for that call type and

Bayesian modeling of JET Li-BES for edge electron density profiles using Gaussian processes

Science.gov (United States)

Kwak, Sehyun; Svensson, Jakob; Brix, Mathias; Ghim, Young-Chul; JET Contributors Collaboration

2015-11-01

A Bayesian model for the JET lithium beam emission spectroscopy (Li-BES) system has been developed to infer edge electron density profiles. The 26 spatial channels measure emission profiles with ~15 ms temporal resolution and ~1 cm spatial resolution. The lithium I (2p-2s) line radiation in an emission spectrum is calculated using a multi-state model, which expresses collisions between the neutral lithium beam atoms and the plasma particles as a set of differential equations. The emission spectrum is described in the model including photon and electronic noise, spectral line shapes, interference filter curves, and relative calibrations. This spectral modeling gets rid of the need of separate background measurements for calculating the intensity of the line radiation. Gaussian processes are applied to model both emission spectrum and edge electron density profile, and the electron temperature to calculate all the rate coefficients is obtained from the JET high resolution Thomson scattering (HRTS) system. The posterior distributions of the edge electron density profile are explored via the numerical technique and the Markov chain Monte Carlo (MCMC) samplings. See the Appendix of F. Romanelli et al., Proceedings of the 25th IAEA Fusion Energy Conference 2014, Saint Petersburg, Russia.

A UML profile for the OBO relation ontology

Science.gov (United States)

2012-01-01

Background Ontologies have increasingly been used in the biomedical domain, which has prompted the emergence of different initiatives to facilitate their development and integration. The Open Biological and Biomedical Ontologies (OBO) Foundry consortium provides a repository of life-science ontologies, which are developed according to a set of shared principles. This consortium has developed an ontology called OBO Relation Ontology aiming at standardizing the different types of biological entity classes and associated relationships. Since ontologies are primarily intended to be used by humans, the use of graphical notations for ontology development facilitates the capture, comprehension and communication of knowledge between its users. However, OBO Foundry ontologies are captured and represented basically using text-based notations. The Unified Modeling Language (UML) provides a standard and widely-used graphical notation for modeling computer systems. UML provides a well-defined set of modeling elements, which can be extended using a built-in extension mechanism named Profile. Thus, this work aims at developing a UML profile for the OBO Relation Ontology to provide a domain-specific set of modeling elements that can be used to create standard UML-based ontologies in the biomedical domain. Results We have studied the OBO Relation Ontology, the UML metamodel and the UML profiling mechanism. Based on these studies, we have proposed an extension to the UML metamodel in conformance with the OBO Relation Ontology and we have defined a profile that implements the extended metamodel. Finally, we have applied the proposed UML profile in the development of a number of fragments from different ontologies. Particularly, we have considered the Gene Ontology (GO), the PRotein Ontology (PRO) and the Xenopus Anatomy and Development Ontology (XAO). Conclusions The use of an established and well-known graphical language in the development of biomedical ontologies provides a more

time series modeling of daily abandoned calls in a call centre

African Journals Online (AJOL)

DJFLEX

Models for evaluating and predicting the short periodic time series in daily ... Ugwuowo (2006) proposed asymmetric angular- linear multivariate regression models, ..... Using the parameter estimates in Table 3, the fitted Fourier series model is ..... For the SARIMA model with the stochastic component also being white noise, ...

Model for radial gas fraction profiles in vertical pipe flow

International Nuclear Information System (INIS)

Lucas, D.; Krepper, E.; Prasser, H.M.

2001-01-01

A one-dimensional model is presented, which predicts the radial volume fraction profiles from a given bubble size distribution. It bases on the assumption of an equilibrium of the forces acting on a bubble perpendicularly to the flow path (non drag forces). For the prediction of the flow pattern this model could be used within an procedure together with appropriate models for local bubble coalescence and break-up. (orig.)

Energy confinement in the T-10 tokamak and canonic profile models

International Nuclear Information System (INIS)

Dnestrovskii, Yu.N.; Pereverzev, G.V.

1988-01-01

A classification of experimental results on electron cyclotron resonance heating (ECRH) is that T-10 tokamak is presented. Analysis of the experiments is consistent with two energy balance models. The first is based on the idea of profile consistency of the plasma current and pressure. The on-axis and off-axis ECRH as well as the heat wave propagation in T-10 can be reasonably represented in this way. In addition, this model allows the L to H mode transition to be described as the bifurcation of the solutions of a set of non-linear equations. The second model is based on the idea of a thermal pinch produced by a toroidal electric field. The electron temperature profiles under ohmic heating as well as under ECRH can be described by this model. Furthermore, this approach explains the cause of the confinement degradation under non-ohmic plasma heating (L-mode). (Author)

The use of conduction model in laser weld profile computation

Science.gov (United States)

Grabas, Bogusław

2007-02-01

Profiles of joints resulting from deep penetration laser beam welding of a flat workpiece of carbon steel were computed. A semi-analytical conduction model solved with Green's function method was used in computations. In the model, the moving heat source was attenuated exponentially in accordance with Beer-Lambert law. Computational results were compared with those in the experiment.

Model for hydrogen isotope backscattering, trapping and depth profiles in C and a-Si

International Nuclear Information System (INIS)

Cohen, S.A.; McCracken, G.M.

1979-03-01

A model of low energy hydrogen trapping and backscattering in carbon and a-silicon is described. Depth profiles are calculated and numerical results presented for various incident angular and energy distributions. The calculations yield a relation between depth profiles and the incident ion energy distribution. The use of this model for tokamak plasma diagnosis is discussed

Geocoronal Balmer α line profile observations and forward-model analysis

Science.gov (United States)

Mierkiewicz, E. J.; Bishop, J.; Roesler, F. L.; Nossal, S. M.

2006-05-01

High spectral resolution geocoronal Balmer α line profile observations from Pine Bluff Observatory (PBO) are presented in the context of forward-model analysis. Because Balmer series column emissions depend significantly on multiple scattering, retrieval of hydrogen parameters of general aeronomic interest from these observations (e.g., the hydrogen column abundance) currently requires a forward modeling approach. This capability is provided by the resonance radiative transfer code LYAO_RT. We have recently developed a parametric data-model comparison search procedure employing an extensive grid of radiative transport model input parameters (defining a 6-dimensional parameter space) to map-out bounds for feasible forward model retrieved atomic hydrogen density distributions. We applied this technique to same-night (March, 2000) ground-based Balmer α data from PBO and geocoronal Lyman β measurements from the Espectrógrafo Ultravioleta extremo para la Radiación Difusa (EURD) instrument on the Spanish satellite MINISAT-1 (provided by J.F. Gómez and C. Morales of the Laboratorio de Astrofisica Espacial y Física Fundamental, INTA, Madrid, Spain) in order to investigate the modeling constraints imposed by two sets of independent geocoronal intensity measurements, both of which rely on astronomical calibration methods. In this poster we explore extending this analysis to the line profile information also contained in the March 2000 PBO Balmer α data set. In general, a decrease in the Doppler width of the Balmer α emission with shadow altitude is a persistent feature in every night of PBO observations in which a wide range of shadow altitudes are observed. Preliminary applications of the LYAO_RT code, which includes the ability to output Doppler line profiles for both the singly and multiply scattered contributions to the Balmer α emission line, displays good qualitative agreement with regard to geocoronal Doppler width trends observed from PBO. Model-data Balmer

Renal cell carcinoma primary cultures maintain genomic and phenotypic profile of parental tumor tissues

International Nuclear Information System (INIS)

Cifola, Ingrid; Magni, Fulvio; Signorini, Stefano; Battaglia, Cristina; Perego, Roberto A; Bianchi, Cristina; Mangano, Eleonora; Bombelli, Silvia; Frascati, Fabio; Fasoli, Ester; Ferrero, Stefano; Di Stefano, Vitalba; Zipeto, Maria A

2011-01-01

Clear cell renal cell carcinoma (ccRCC) is characterized by recurrent copy number alterations (CNAs) and loss of heterozygosity (LOH), which may have potential diagnostic and prognostic applications. Here, we explored whether ccRCC primary cultures, established from surgical tumor specimens, maintain the DNA profile of parental tumor tissues allowing a more confident CNAs and LOH discrimination with respect to the original tissues. We established a collection of 9 phenotypically well-characterized ccRCC primary cell cultures. Using the Affymetrix SNP array technology, we performed the genome-wide copy number (CN) profiling of both cultures and corresponding tumor tissues. Global concordance for each culture/tissue pair was assayed evaluating the correlations between whole-genome CN profiles and SNP allelic calls. CN analysis was performed using the two CNAG v3.0 and Partek software, and comparing results returned by two different algorithms (Hidden Markov Model and Genomic Segmentation). A very good overlap between the CNAs of each culture and corresponding tissue was observed. The finding, reinforced by high whole-genome CN correlations and SNP call concordances, provided evidence that each culture was derived from its corresponding tissue and maintained the genomic alterations of parental tumor. In addition, primary culture DNA profile remained stable for at least 3 weeks, till to third passage. These cultures showed a greater cell homogeneity and enrichment in tumor component than original tissues, thus enabling a better discrimination of CNAs and LOH. Especially for hemizygous deletions, primary cultures presented more evident CN losses, typically accompanied by LOH; differently, in original tissues the intensity of these deletions was weaken by normal cell contamination and LOH calls were missed. ccRCC primary cultures are a reliable in vitro model, well-reproducing original tumor genetics and phenotype, potentially useful for future functional approaches

Superdiffusion in a non-Markovian random walk model with a Gaussian memory profile

Science.gov (United States)

Borges, G. M.; Ferreira, A. S.; da Silva, M. A. A.; Cressoni, J. C.; Viswanathan, G. M.; Mariz, A. M.

2012-09-01

Most superdiffusive Non-Markovian random walk models assume that correlations are maintained at all time scales, e.g., fractional Brownian motion, Lévy walks, the Elephant walk and Alzheimer walk models. In the latter two models the random walker can always "remember" the initial times near t = 0. Assuming jump size distributions with finite variance, the question naturally arises: is superdiffusion possible if the walker is unable to recall the initial times? We give a conclusive answer to this general question, by studying a non-Markovian model in which the walker's memory of the past is weighted by a Gaussian centered at time t/2, at which time the walker had one half the present age, and with a standard deviation σt which grows linearly as the walker ages. For large widths we find that the model behaves similarly to the Elephant model, but for small widths this Gaussian memory profile model behaves like the Alzheimer walk model. We also report that the phenomenon of amnestically induced persistence, known to occur in the Alzheimer walk model, arises in the Gaussian memory profile model. We conclude that memory of the initial times is not a necessary condition for generating (log-periodic) superdiffusion. We show that the phenomenon of amnestically induced persistence extends to the case of a Gaussian memory profile.

Self-organization of hot plasmas the canonical profile transport model

CERN Document Server

Dnestrovskij, Yu N

2015-01-01

In this monograph the author presents the Canonical Profile Transport Model or CPTM as a rather general mathematical framework to simulate plasma discharges.The description of hot plasmas in a magnetic fusion device is a very challenging task and many plasma properties still lack a physical explanation. One important property is plasma self-organization.It is very well known from experiments that the radial profile of the plasma pressure and temperature remains rather unaffected by changes of the deposited power or plasma density. The attractiveness of the CPTM is that it includes the effect o

Evolution of Cross-Shore Profile Models for Sustainable Coastal Design

Science.gov (United States)

Ismail, Nabil; El-Sayed, Mohamed

2014-05-01

Selection and evaluation of coastal structures are correlated with environmental wave and current parameters as well as cross shore profiles. The coupling between the environmental conditions and cross shore profiles necessitates the ability to predict reasonably the cross shore profiles. Results obtained from the validation of a cross-shore profile evolution model, Uniform Beach Sediment Transport-Time-Averaged Cross-Shore (UNIBEST-TC), were examined and further analyzed to reveal the reasons for the discrepancy between the model predictions of the field data at the surf zone of the Duck Beach in North Carolina, USA. The UNIBEST model was developed to predict the main cross shore parameters of wave height, direction, cross shore and long shore currents. However, the results of the model predictions are generally satisfactory for wave height and direction but not satisfactory for the remaining parameters. This research is focused on exploring the discrepancy between the model predictions and the field data of the Duck site, and conducting further analyses to recommend model refinements. The discrepancy is partially attributed due to the fact that the measured values, were taken close to the seabed, while the predicted values are the depth-averaged velocity. Further examination indicated that UNIBEST-TC model runs consider the RMS of the wave height spectrum with a constant gamma-value from the offshore wave spectrum at 8.0m depth. To confirm this argument, a Wavelet Analysis was applied to the time series of wave height and longshore current velocity parameters at the Duck site. The significant wave height ranged between 0.6m and 4.0m while the frequencies ranged between 0.08 to 0.2Hz at 8.0m water depth. Four cases corresponding to events of both high water level and low water level at Duck site were considered in this study. The results show that linear and non-linear interaction between wave height and long-shore current occur over the range of frequencies

EFFECTS OF NITROGEN PHOTOABSORPTION CROSS SECTION RESOLUTION ON MINOR SPECIES VERTICAL PROFILES IN TITAN’S UPPER ATMOSPHERE

International Nuclear Information System (INIS)

Luspay-Kuti, A.; Mandt, K. E.; Greathouse, T. K.; Plessis, S.

2015-01-01

The significant variations in both measured and modeled densities of minor species in Titan’s atmosphere call for the evaluation of possible influencing factors in photochemical modeling. The effect of nitrogen photoabsorption cross section selection on the modeled vertical profiles of minor species is analyzed here, with particular focus on C 2 H 6 and HCN. Our results show a clear impact of cross sections used on all neutral and ion species studied. Affected species include neutrals and ions that are not primary photochemical products, including species that do not even contain nitrogen. The results indicate that photochemical models that employ low-resolution cross sections may significantly miscalculate the vertical profiles of minor species. Such differences are expected to have important implications for Titan’s overall atmospheric structure and chemistry

EFFECTS OF NITROGEN PHOTOABSORPTION CROSS SECTION RESOLUTION ON MINOR SPECIES VERTICAL PROFILES IN TITAN’S UPPER ATMOSPHERE

Energy Technology Data Exchange (ETDEWEB)

Luspay-Kuti, A.; Mandt, K. E.; Greathouse, T. K. [Space Science and Engineering Division, Southwest Research Institute, 6220 Culebra Road, San Antonio, TX 78238 (United States); Plessis, S., E-mail: aluspaykuti@swri.edu [ICES, The University of Texas at Austin, 201 East 24th Street, Austin, TX 78712 (United States)

2015-03-01

The significant variations in both measured and modeled densities of minor species in Titan’s atmosphere call for the evaluation of possible influencing factors in photochemical modeling. The effect of nitrogen photoabsorption cross section selection on the modeled vertical profiles of minor species is analyzed here, with particular focus on C{sub 2}H{sub 6} and HCN. Our results show a clear impact of cross sections used on all neutral and ion species studied. Affected species include neutrals and ions that are not primary photochemical products, including species that do not even contain nitrogen. The results indicate that photochemical models that employ low-resolution cross sections may significantly miscalculate the vertical profiles of minor species. Such differences are expected to have important implications for Titan’s overall atmospheric structure and chemistry.

Using Call Detail Records for Modeling Coastal Recreation Behavior

Science.gov (United States)

Call data records (CDR) are data from cellular phone networks that can be used to understand human mobility or where people go spatially. They can be used to estimate visitation to an area such as a coastal access point for a given time window, as well as provide information on t...

Study on possibility of plasma current profile determination using an analytical model of tokamak equilibrium

International Nuclear Information System (INIS)

Moriyama, Shin-ichi; Hiraki, Naoji

1996-01-01

The possibility of determining the current profile of tokamak plasma from the external magnetic measurements alone is investigated using an analytical model of tokamak equilibrium. The model, which is based on an approximate solution of the Grad-Shafranov equation, can set a plasma current profile expressed with four free parameters of the total plasma current, the poloidal beta, the plasma internal inductance and the axial safety factor. The analysis done with this model indicates that, for a D-shaped plasma, the boundary poloidal magnetic field prescribing the external magnetic field distribution is dependent on the axial safety factor in spite of keeping the boundary safety factor and the plasma internal inductance constant. This suggests that the plasma current profile is reversely determined from the external magnetic analysis. The possibility and the limitation of current profile determination are discussed through this analytical result. (author)

UML Profile for Mining Process: Supporting Modeling and Simulation Based on Metamodels of Activity Diagram

Directory of Open Access Journals (Sweden)

Andrea Giubergia

2014-01-01

Full Text Available An UML profile describes lightweight extension mechanism to the UML by defining custom stereotypes, tagged values, and constraints. They are used to adapt UML metamodel to different platforms and domains. In this paper we present an UML profile for models supporting event driving simulation. In particular, we use the Arena simulation tool and we focus on the mining process domain. Profiles provide an easy way to obtain well-defined specifications, regulated by the Object Management Group (OMG. They can be used as a presimulation technique to obtain solid models for the mining industry. In this work we present a new profile to extend the UML metamodel; in particular we focus on the activity diagram. This extended model is applied to an industry problem involving loading and transportation of minerals in the field of mining process.

Novel Profiling Model and Side Effects of Helical Scan Silicon Heads

NARCIS (Netherlands)

Hozoi, A.; Groenland, J.P.J.; Albertini, J.B.; Lodder, J.C.

2002-01-01

Partial erasure of track edges was directly measured from triple-track patterns using a novel model to interpret the output profiles. The model is based on representing the read head as the sum of a reference width, wavelength independent, and two side reading effective widths that are wavelength

The uses of mental health telephone counselling services for Chinese speaking people in New Zealand: demographics, presenting problems, outcome and evaluation of the calls.

Science.gov (United States)

Yang Dong, Christine

2016-09-09

This study aimed to investigate the call profiles of a Chinese-speaking mental health counselling helpline service in New Zealand (Chinese Lifeline provided by Lifeline Aotearoa) and to evaluate the calls and explore the possible factors influencing the outcome of the calls. A random sample of 151 answered calls was involved. Descriptive analysis with appropriate statistical tests was used to analyse the client profile and outcome data. The majority of the calls were made by female callers, aged between 21-60 both single and married. Top three presenting problems were: 1) mental health issues (82.1%); 2) family/partner relationship issues (47.0%) and 3) communication and related difficulties (45.0%). The majority of the calls (65%) ended after a clear decision in overcoming the issues made by the caller, with the help from the counsellor. Discussing mental health issues, grief and loss issues, and communication and related difficulties were shown to have influenced length of calls (p<0.05). Caller's age, frequency of calls, discussing relationship problems with family/partner, and physical problems were shown to have influenced the helpline counsellors' satisfaction of the helpfulness of the calls (p<0.05). The service receives calls from callers with a wide range of demographics and a large variety of presenting issues. This study identified several important factors which influenced counsellors' satisfaction of the calls and the length of the calls.

Major differences between human atopic dermatitis and murine models as determined by global transcriptomic profiling

DEFF Research Database (Denmark)

Ewald, David Adrian; Noda, Shinji; Oliva, Margeaux

2017-01-01

, and a comparison of these models with the human AD transcriptomic fingerprint is lacking. We sought to evaluate the transcriptomic profiles of six common murine models and determine how they relate to human AD skin. Transcriptomic profiling was performed using microarrays and qRT-PCR on biopsies from NC/Nga, flaky...

47 CFR 22.921 - 911 call processing procedures; 911-only calling mode.

Science.gov (United States)

2010-10-01

... programming in the mobile unit that determines the handling of a non-911 call and permit the call to be... CARRIER SERVICES PUBLIC MOBILE SERVICES Cellular Radiotelephone Service § 22.921 911 call processing procedures; 911-only calling mode. Mobile telephones manufactured after February 13, 2000 that are capable of...

Comprehensive analysis of ultrasonic vocalizations in a mouse model of fragile X syndrome reveals limited, call type specific deficits.

Directory of Open Access Journals (Sweden)

Snigdha Roy

Full Text Available Fragile X syndrome (FXS is a well-recognized form of inherited mental retardation, caused by a mutation in the fragile X mental retardation 1 (Fmr1 gene. The gene is located on the long arm of the X chromosome and encodes fragile X mental retardation protein (FMRP. Absence of FMRP in fragile X patients as well as in Fmr1 knockout (KO mice results, among other changes, in abnormal dendritic spine formation and altered synaptic plasticity in the neocortex and hippocampus. Clinical features of FXS include cognitive impairment, anxiety, abnormal social interaction, mental retardation, motor coordination and speech articulation deficits. Mouse pups generate ultrasonic vocalizations (USVs when isolated from their mothers. Whether those social ultrasonic vocalizations are deficient in mouse models of FXS is unknown. Here we compared isolation-induced USVs generated by pups of Fmr1-KO mice with those of their wild type (WT littermates. Though the total number of calls was not significantly different between genotypes, a detailed analysis of 10 different categories of calls revealed that loss of Fmr1 expression in mice causes limited and call-type specific deficits in ultrasonic vocalization: the carrier frequency of flat calls was higher, the percentage of downward calls was lower and that the frequency range of complex calls was wider in Fmr1-KO mice compared to their WT littermates.

dDocent: a RADseq, variant-calling pipeline designed for population genomics of non-model organisms.

Science.gov (United States)

Puritz, Jonathan B; Hollenbeck, Christopher M; Gold, John R

2014-01-01

Restriction-site associated DNA sequencing (RADseq) has become a powerful and useful approach for population genomics. Currently, no software exists that utilizes both paired-end reads from RADseq data to efficiently produce population-informative variant calls, especially for non-model organisms with large effective population sizes and high levels of genetic polymorphism. dDocent is an analysis pipeline with a user-friendly, command-line interface designed to process individually barcoded RADseq data (with double cut sites) into informative SNPs/Indels for population-level analyses. The pipeline, written in BASH, uses data reduction techniques and other stand-alone software packages to perform quality trimming and adapter removal, de novo assembly of RAD loci, read mapping, SNP and Indel calling, and baseline data filtering. Double-digest RAD data from population pairings of three different marine fishes were used to compare dDocent with Stacks, the first generally available, widely used pipeline for analysis of RADseq data. dDocent consistently identified more SNPs shared across greater numbers of individuals and with higher levels of coverage. This is due to the fact that dDocent quality trims instead of filtering, incorporates both forward and reverse reads (including reads with INDEL polymorphisms) in assembly, mapping, and SNP calling. The pipeline and a comprehensive user guide can be found at http://dDocent.wordpress.com.

CPHmodels-3.0--remote homology modeling using structure-guided sequence profiles.

Science.gov (United States)

Nielsen, Morten; Lundegaard, Claus; Lund, Ole; Petersen, Thomas Nordahl

2010-07-01

CPHmodels-3.0 is a web server predicting protein 3D structure by use of single template homology modeling. The server employs a hybrid of the scoring functions of CPHmodels-2.0 and a novel remote homology-modeling algorithm. A query sequence is first attempted modeled using the fast CPHmodels-2.0 profile-profile scoring function suitable for close homology modeling. The new computational costly remote homology-modeling algorithm is only engaged provided that no suitable PDB template is identified in the initial search. CPHmodels-3.0 was benchmarked in the CASP8 competition and produced models for 94% of the targets (117 out of 128), 74% were predicted as high reliability models (87 out of 117). These achieved an average RMSD of 4.6 A when superimposed to the 3D structure. The remaining 26% low reliably models (30 out of 117) could superimpose to the true 3D structure with an average RMSD of 9.3 A. These performance values place the CPHmodels-3.0 method in the group of high performing 3D prediction tools. Beside its accuracy, one of the important features of the method is its speed. For most queries, the response time of the server is web server is available at http://www.cbs.dtu.dk/services/CPHmodels/.

CGDM: collaborative genomic data model for molecular profiling data using NoSQL.

Science.gov (United States)

Wang, Shicai; Mares, Mihaela A; Guo, Yi-Ke

2016-12-01

High-throughput molecular profiling has greatly improved patient stratification and mechanistic understanding of diseases. With the increasing amount of data used in translational medicine studies in recent years, there is a need to improve the performance of data warehouses in terms of data retrieval and statistical processing. Both relational and Key Value models have been used for managing molecular profiling data. Key Value models such as SeqWare have been shown to be particularly advantageous in terms of query processing speed for large datasets. However, more improvement can be achieved, particularly through better indexing techniques of the Key Value models, taking advantage of the types of queries which are specific for the high-throughput molecular profiling data. In this article, we introduce a Collaborative Genomic Data Model (CGDM), aimed at significantly increasing the query processing speed for the main classes of queries on genomic databases. CGDM creates three Collaborative Global Clustering Index Tables (CGCITs) to solve the velocity and variety issues at the cost of limited extra volume. Several benchmarking experiments were carried out, comparing CGDM implemented on HBase to the traditional SQL data model (TDM) implemented on both HBase and MySQL Cluster, using large publicly available molecular profiling datasets taken from NCBI and HapMap. In the microarray case, CGDM on HBase performed up to 246 times faster than TDM on HBase and 7 times faster than TDM on MySQL Cluster. In single nucleotide polymorphism case, CGDM on HBase outperformed TDM on HBase by up to 351 times and TDM on MySQL Cluster by up to 9 times. The CGDM source code is available at https://github.com/evanswang/CGDM. y.guo@imperial.ac.uk. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

A cervid vocal fold model suggests greater glottal efficiency in calling at high frequencies.

Directory of Open Access Journals (Sweden)

Ingo R Titze

2010-08-01

Full Text Available Male Rocky Mountain elk (Cervus elaphus nelsoni produce loud and high fundamental frequency bugles during the mating season, in contrast to the male European Red Deer (Cervus elaphus scoticus who produces loud and low fundamental frequency roaring calls. A critical step in understanding vocal communication is to relate sound complexity to anatomy and physiology in a causal manner. Experimentation at the sound source, often difficult in vivo in mammals, is simulated here by a finite element model of the larynx and a wave propagation model of the vocal tract, both based on the morphology and biomechanics of the elk. The model can produce a wide range of fundamental frequencies. Low fundamental frequencies require low vocal fold strain, but large lung pressure and large glottal flow if sound intensity level is to exceed 70 dB at 10 m distance. A high-frequency bugle requires both large muscular effort (to strain the vocal ligament and high lung pressure (to overcome phonation threshold pressure, but at least 10 dB more intensity level can be achieved. Glottal efficiency, the ration of radiated sound power to aerodynamic power at the glottis, is higher in elk, suggesting an advantage of high-pitched signaling. This advantage is based on two aspects; first, the lower airflow required for aerodynamic power and, second, an acoustic radiation advantage at higher frequencies. Both signal types are used by the respective males during the mating season and probably serve as honest signals. The two signal types relate differently to physical qualities of the sender. The low-frequency sound (Red Deer call relates to overall body size via a strong relationship between acoustic parameters and the size of vocal organs and body size. The high-frequency bugle may signal muscular strength and endurance, via a 'vocalizing at the edge' mechanism, for which efficiency is critical.

A Relational Account of Call-by-Value Sequentiality

DEFF Research Database (Denmark)

Riecke, Jon Gary; Sandholm, Anders Bo

2002-01-01

We construct a model for FPC, a purely functional, sequential, call-by-value language. The model is built from partial continuous functions, in the style of Plotkin, further constrained to be uniform with respect to a class of logical relations. We prove that the model is fully abstract....

A comparison of boundary-layer heights inferred from wind-profiler backscatter profiles with diagnostic calculations using regional model forecasts

Energy Technology Data Exchange (ETDEWEB)

Baltink, H.K.; Holtslag, A.A.M. [Royal Netherlands Meteorological Inst., KNMI, De Bilt (Netherlands)

1997-10-01

From October 1994 through January 1997 the Tropospheric Energy Budget Experiment (TEBEX) was executed by KNMI. The main objectives are to study boundary layer processes and cloud variability on the sub-grid scale of present Global Climate Models and to improve the related sub-grid parametrizations. A suite of instruments was deployed to measure a large number of variables. Measurements to characterize ABL processes were focussed around the 200 m high meteorological observation tower of the KNMI in Cabauw. In the framework of TEBEX a 1290 MHz wind-profiler/RASS was installed in July 1994 at 300 m from tower. Data collected during TEBEX are used to assess the performance of a Regional Atmospheric Climate Model (RACMO). This climate model runs also in a operational forecast mode once a day. The diagnostic ABL-height (h{sub model}) is calculated from the RACMO forecast output. A modified Richardson`s number method extended with an excess parcel temperature is applied for all stability conditions. We present the preliminary results of a comparison of h{sub model} from forecasts with measured h{sub TS} derived from profiler and sodar data for July 1995. (au)

A Mathematical Model for Non-monotonic Deposition Profiles in Deep Bed Filtration Systems

DEFF Research Database (Denmark)

Yuan, Hao; Shapiro, Alexander

2011-01-01

A mathematical model for suspension/colloid flow in porous media and non-monotonic deposition is proposed. It accounts for the migration of particles associated with the pore walls via the second energy minimum (surface associated phase). The surface associated phase migration is characterized...... by advection and diffusion/dispersion. The proposed model is able to produce a nonmonotonic deposition profile. A set of methods for estimating the modeling parameters is provided in the case of minimal particle release. The estimation can be easily performed with available experimental information....... The numerical modeling results highly agree with the experimental observations, which proves the ability of the model to catch a non-monotonic deposition profile in practice. An additional equation describing a mobile population behaving differently from the injected population seems to be a sufficient...

Modeling of Aerosol Vertical Profiles Using GIS and Remote Sensing

Directory of Open Access Journals (Sweden)

Kwon Ho Lee

2009-06-01

Full Text Available The use of Geographic Information Systems (GIS and Remote Sensing (RS by climatologists, environmentalists and urban planners for three dimensional modeling and visualization of the landscape is well established. However no previous study has implemented these techniques for 3D modeling of atmospheric aerosols because air quality data is traditionally measured at ground points, or from satellite images, with no vertical dimension. This study presents a prototype for modeling and visualizing aerosol vertical profiles over a 3D urban landscape in Hong Kong. The method uses a newly developed technique for the derivation of aerosol vertical profiles from AERONET sunphotometer measurements and surface visibility data, and links these to a 3D urban model. This permits automated modeling and visualization of aerosol concentrations at different atmospheric levels over the urban landscape in near-real time. Since the GIS platform permits presentation of the aerosol vertical distribution in 3D, it can be related to the built environment of the city. Examples are given of the applications of the model, including diagnosis of the relative contribution of vehicle emissions to pollution levels in the city, based on increased near-surface concentrations around weekday rush-hour times. The ability to model changes in air quality and visibility from ground level to the top of tall buildings is also demonstrated, and this has implications for energy use and environmental policies for the tall mega-cities of the future.

A new class of information complexity (ICOMP) criteria with an application to customer profiling and segmentation

OpenAIRE

Bozdogan, Hamparsun

2010-01-01

This paper introduces several forms of a new class of information-theoretic measure of complexity criterion called ICOMP as a decision rule for model selection in statistical modeling to help provide new approaches relevant to statistical inference. The practical utility and the importance of ICOMP is illustrated by providing a real numerical example in data mining of mobile phone data for customer profiling and segmentation of mobile phone customers using a novel multi-class support vector m...

Prevendo a demanda de ligações em um call center por meio de um modelo de Regressão Múltipla Forecasting a call center demand using a Multiple Regression model

Directory of Open Access Journals (Sweden)

Marco Aurélio Carino Bouzada

2009-09-01

Full Text Available Este trabalho descreve - por meio do estudo de um caso - o problema da previsão de demanda de chamadas para um determinado produto no call center de uma grande empresa brasileira do setor - a Contax - e como ele foi abordado com o uso de Regressão Múltipla com variáveis dummy. Depois de destacar e justificar a importância do tema, o estudo apresenta uma breve revisão de literatura acerca de métodos de previsão de demanda e de sua aplicação em call centers. O caso é descrito, contextualizando, inicialmente, a empresa estudada e descrevendo, a seguir, a forma como ela lida com o problema de previsão de demanda de chamadas para o produto 103 - serviços relacionados à telefonia fixa. Um modelo de Regressão Múltipla com variáveis dummy é, então, desenvolvido para servir como base do processo de previsão de demanda proposto. Este modelo utiliza informações disponíveis capazes de influenciar a demanda, tais como o dia da semana, a ocorrência ou não de feriado e a proximidade da data com eventos críticos, como a chegada da conta à residência do cliente e seu vencimento; e apresentou ganhos de acurácia da ordem de 3 pontos percentuais para o período estudado, quando comparado com a ferramenta anteriormente em uso.This work describes - with the aid of a case study -a demand forecast problem for a specific product reported to the call center of a large Brazilian company in an industry called Contax, and the way it was approached with the use of Multiple Regression using dummy variables. After highlighting and justifying the studied matter relevance, the article presents a small literature review regarding demand forecast methods and their use in the call center industry. The case is described presenting the studied company and the way it deals with the Forecasting Demand for a telephone all center regarding telephone services products. Therefore, a Multiple Regression with dummy variables model was developed to work as the

Valuation of European Call Option via Inverse Fourier Transform

Directory of Open Access Journals (Sweden)

Rubenis Oskars

2017-12-01

Full Text Available Very few models allow expressing European call option price in closed form. Out of them, the famous Black- Scholes approach sets strong constraints - innovations should be normally distributed and independent. Availability of a corresponding characteristic function of log returns of underlying asset in analytical form allows pricing European call option by application of inverse Fourier transform. Characteristic function corresponds to Normal Inverse Gaussian (NIG probability density function. NIG distribution is obtained based on assumption that time series of log returns follows APARCH process. Thus, volatility clustering and leptokurtic nature of log returns are taken into account. The Fast Fourier transform based on trapezoidal quadrature is numerically unstable if a standard cumulative probability function is used. To solve the problem, a dampened cumulative probability is introduced. As a computation tool Matlab framework is chosen because it contains many effective vectorization tools that greatly enhance code readability and maintenance. The characteristic function of Normal Inverse Gaussian distribution is taken and exercised with the chosen set of parameters. Finally, the call price dependence on strike price is obtained and rendered in XY plot. Valuation of European call option with analytical form of characteristic function allows further developing models with higher accuracy, as well as developing models for some exotic options.

Modeling carbon cycle process of soil profile in Loess Plateau of China

Science.gov (United States)

Yu, Y.; Finke, P.; Guo, Z.; Wu, H.

2011-12-01

SoilGen2 is a process-based model, which could reconstruct soil formation under various climate conditions, parent materials, vegetation types, slopes, expositions and time scales. Both organic and inorganic carbon cycle processes could be simulated, while the later process is important in carbon cycle of arid and semi-arid regions but seldom being studied. After calibrating parameters of dust deposition rate and segments depth affecting elements transportation and deposition in the profile, modeling results after 10000 years were confronted with measurements of two soil profiles in loess plateau of China, The simulated trends of organic carbon and CaCO3 in the profile are similar to measured values. Relative sensitivity analysis for carbon cycle process have been done and the results show that the change of organic carbon in long time scale is more sensitive to precipitation, temperature, plant carbon input and decomposition parameters (decomposition rate of humus, ratio of CO2/(BIO+HUM), etc.) in the model. As for the inorganic carbon cycle, precipitation and potential evaporation are important for simulation quality, while the leaching and deposition of CaCO3 are not sensitive to pCO2 and temperature of atmosphere.

Profile control simulations and experiments on TCV: a controller test environment and results using a model-based predictive controller

Science.gov (United States)

Maljaars, E.; Felici, F.; Blanken, T. C.; Galperti, C.; Sauter, O.; de Baar, M. R.; Carpanese, F.; Goodman, T. P.; Kim, D.; Kim, S. H.; Kong, M.; Mavkov, B.; Merle, A.; Moret, J. M.; Nouailletas, R.; Scheffer, M.; Teplukhina, A. A.; Vu, N. M. T.; The EUROfusion MST1-team; The TCV-team

2017-12-01

The successful performance of a model predictive profile controller is demonstrated in simulations and experiments on the TCV tokamak, employing a profile controller test environment. Stable high-performance tokamak operation in hybrid and advanced plasma scenarios requires control over the safety factor profile (q-profile) and kinetic plasma parameters such as the plasma beta. This demands to establish reliable profile control routines in presently operational tokamaks. We present a model predictive profile controller that controls the q-profile and plasma beta using power requests to two clusters of gyrotrons and the plasma current request. The performance of the controller is analyzed in both simulation and TCV L-mode discharges where successful tracking of the estimated inverse q-profile as well as plasma beta is demonstrated under uncertain plasma conditions and the presence of disturbances. The controller exploits the knowledge of the time-varying actuator limits in the actuator input calculation itself such that fast transitions between targets are achieved without overshoot. A software environment is employed to prepare and test this and three other profile controllers in parallel in simulations and experiments on TCV. This set of tools includes the rapid plasma transport simulator RAPTOR and various algorithms to reconstruct the plasma equilibrium and plasma profiles by merging the available measurements with model-based predictions. In this work the estimated q-profile is merely based on RAPTOR model predictions due to the absence of internal current density measurements in TCV. These results encourage to further exploit model predictive profile control in experiments on TCV and other (future) tokamaks.

Theory-based transport simulations of TFTR L-mode temperature profiles

International Nuclear Information System (INIS)

Bateman, G.

1991-01-01

The temperature profiles from a selection of TFTR L-mode discharges are simulated with the 1-1/2-D BALDUR transport code using a combination of theoretically derived transport models, called the Multi-Mode Model. The present version of the Multi-Mode Model consists of effective thermal diffusivities resulting from trapped electron modes and ion temperature gradient (η i ) modes, which dominate in the core of the plasma, together with resistive ballooning modes, which dominate in the periphery. Within the context of this transport model and the TFTR simulations reported here, the scaling of confinement with heating power comes from the temperature dependence of the η i and trapped electron modes, while the scaling with current comes mostly from resistive ballooning modes. 24 refs., 16 figs., 3 tabs

Profiles in Leadership: Enhancing Learning through Model and Theory Building.

Science.gov (United States)

Mello, Jeffrey A.

2003-01-01

A class assignment was designed to present factors affecting leadership dynamics, allow practice in model and theory building, and examine leadership from multicultural perspectives. Students developed a profile of a fictional or real leader and analyzed qualities, motivations, context, and effectiveness in written and oral presentations.…

CLASH-VLT: testing the nature of gravity with galaxy cluster mass profiles

Energy Technology Data Exchange (ETDEWEB)

Pizzuti, L.; Sartoris, B.; Borgani, S.; Girardi, M. [Dipartimento di Fisica, Sezione di Astronomia, Università di Trieste, Via Tiepolo 11, I-34143 Trieste (Italy); Amendola, L. [Institut für Theoretische Physik, Universität Heidelberg, Philosophenweg 16, D-69120 Heidelberg (Germany); Umetsu, K. [5 Institute of Astronomy and Astrophysics, Academia Sinica, P.O. Box 23-141, Taipei 10617, Taiwan (China); Biviano, A.; Balestra, I.; Nonino, M. [INAF—Osservatorio Astronomico di Trieste, Via Tiepolo 11, I-34143 Trieste (Italy); Rosati, P. [University Observatory Munich, Scheinerstrasse 1, D-81679 Mu\\' nchen (Germany); Caminha, G.B. [Dipartimento di Fisica e Scienze della Terra, Università di Ferrara, Via Saragat 1, I-44122 Ferrara (Italy); Frye, B. [Steward Observatory/Department of Astronomy, University of Arizona, 933 N Cherry Ave, Tucson, AZ 85721 (United States); Koekemoer, A. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Grillo, C. [Dark Cosmology Centre, Niels Bohr Institute, University of Copenhagen, Juliane Maries Vej 30, DK-2100 Copenhagen (Denmark); Lombardi, M. [Dipartimento di Fisica, Università degli Studi di Milano, via Celoria 16, I-20133 Milan (Italy); Mercurio, A., E-mail: pizzuti@oats.inaf.it, E-mail: barbara.sartoris@gmail.com, E-mail: borgani@oats.inaf.it, E-mail: l.amendola@thphys.uniheidelberg.de [Osservatorio Astronomico di Capodimonte, Via Moiariello 16, I-80131 Napoli (Italy)

2016-04-01

We use high-precision kinematic and lensing measurements of the total mass profile of the dynamically relaxed galaxy cluster MACS J1206.2-0847 at z=0.44 to estimate the value of the ratio η=Ψ/Φ between the two scalar potentials in the linear perturbed Friedmann-Lemaitre-Robertson-Walker metric. An accurate measurement of this ratio, called anisotropic stress, could show possible, interesting deviations from the predictions of the theory of General Relativity, according to which Ψ should be equal to Φ. Complementary kinematic and lensing mass profiles were derived from exhaustive analyses using the data from the Cluster Lensing And Supernova survey with Hubble (CLASH) and the spectroscopic follow-up with the Very Large Telescope (CLASH-VLT). Whereas the kinematic mass profile tracks only the time-time part of the perturbed metric (i.e. only Φ), the lensing mass profile reflects the contribution of both time-time and space-space components (i.e. the sum Φ+Ψ). We thus express η as a function of the mass profiles and perform our analysis over the radial range 0.5 Mpc≤ r≤ r{sub 200}=1.96 Mpc. Using a spherical Navarro-Frenk-White mass profile, which well fits the data, we obtain η(r{sub 200})=1.01 {sub −0.28}{sup +0.31} at the 68% C.L. We discuss the effect of assuming different functional forms for mass profiles and of the orbit anisotropy in the kinematic reconstruction. Interpreting this result within the well-studied f(R) modified gravity model, the constraint on η translates into an upper bound to the interaction length (inverse of the scalaron mass) smaller than 2 Mpc. This tight constraint on the f(R) interaction range is however substantially relaxed when systematic uncertainties in the analysis are considered. Our analysis highlights the potential of this method to detect deviations from general relativity, while calling for the need of further high-quality data on the total mass distribution of clusters and improved control on systematic

A model for predicting the radial power profile in a fuel pin

International Nuclear Information System (INIS)

Palmer, I.D.; Hesketh, K.W.; Jackson, P.A.

1983-01-01

A simple, fast running computer program for calculating radial power profiles, throughout life, in both standard and duplex fuel pellets for all types of thermal reactor has been developed. The code sub-divides the pellet into a number of annuli for each of which it solves for the concentrations of uranium and plutonium and hence calculates a mean inverse diffusion length. The diffusion equation is solved in terms of Bessel functions and the resulting flux profile multiplied by the concentration profiles to give a radial rating profile which is normalised to unity. The model shows good agreement with the results of detailed physics calculations for different thermal reactors over a wide burn-up range. Its incorporation into the HOTROD-4C and SLEUTH-SEER-77 fuel performance codes has led to a negligible increase in running times. (author)

Pepsi-SAXS : an adaptive method for rapid and accurate computation of small-angle X-ray scattering profiles

OpenAIRE

Grudinin , Sergei; Garkavenko , Maria; Kazennov , Andrei

2017-01-01

International audience; A new method called Pepsi-SAXS is presented that calculates small-angle X-ray scattering profiles from atomistic models. The method is based on the multipole expansion scheme and is significantly faster compared with other tested methods. In particular, using the Nyquist–Shannon–Kotelnikov sampling theorem, the multipole expansion order is adapted to the size of the model and the resolution of the experimental data. It is argued that by using the adaptive expansion ord...

Modeling of immision from power plants using stream-diffusion model

International Nuclear Information System (INIS)

Kanevce, Lj.; Kanevce, G.; Markoski, A.

1996-01-01

Analyses of simple empirical and integral immision models, comparing with complex three dimensional differential models is given. Complex differential models needs huge computer power, so they can't be useful for practical engineering calculations. In this paper immision modeling, using stream-diffusion approach is presented. Process of dispersion is divided into two parts. First part is called stream part, it's near the source of the pollutants, and it's presented with defected turbulent jet in wind field. This part finished when the velocity of stream (jet) becomes equal with wind speed. Boundary conditions in the end of the first part, are initial for the second, called diffusion part, which is modeling with tri dimensional diffusion equation. Gradient of temperature, wind speed profile and coefficient of diffusion in this model must not be constants, they can change with the height. Presented model is much simpler than the complete meteorological differential models which calculates whole fields of meteorological parameters. Also, it is more complex and gives more valuable results for dispersion of pollutants from widely used integral and empirical models

Online scheduling policies for multiclass call centers with impatient customers

NARCIS (Netherlands)

Jouini, O.; Pot, S.A.; Koole, G.M.; Dallery, Y.

2010-01-01

We consider a call center with two classes of impatient customers: premium and regular classes. Modeling our call center as a multiclass GI / GI / s + M queue, we focus on developing scheduling policies that satisfy a target ratio constraint on the abandonment probabilities of premium customers to

Renal cell carcinoma primary cultures maintain genomic and phenotypic profile of parental tumor tissues.

Science.gov (United States)

Cifola, Ingrid; Bianchi, Cristina; Mangano, Eleonora; Bombelli, Silvia; Frascati, Fabio; Fasoli, Ester; Ferrero, Stefano; Di Stefano, Vitalba; Zipeto, Maria A; Magni, Fulvio; Signorini, Stefano; Battaglia, Cristina; Perego, Roberto A

2011-06-13

Clear cell renal cell carcinoma (ccRCC) is characterized by recurrent copy number alterations (CNAs) and loss of heterozygosity (LOH), which may have potential diagnostic and prognostic applications. Here, we explored whether ccRCC primary cultures, established from surgical tumor specimens, maintain the DNA profile of parental tumor tissues allowing a more confident CNAs and LOH discrimination with respect to the original tissues. We established a collection of 9 phenotypically well-characterized ccRCC primary cell cultures. Using the Affymetrix SNP array technology, we performed the genome-wide copy number (CN) profiling of both cultures and corresponding tumor tissues. Global concordance for each culture/tissue pair was assayed evaluating the correlations between whole-genome CN profiles and SNP allelic calls. CN analysis was performed using the two CNAG v3.0 and Partek software, and comparing results returned by two different algorithms (Hidden Markov Model and Genomic Segmentation). A very good overlap between the CNAs of each culture and corresponding tissue was observed. The finding, reinforced by high whole-genome CN correlations and SNP call concordances, provided evidence that each culture was derived from its corresponding tissue and maintained the genomic alterations of parental tumor. In addition, primary culture DNA profile remained stable for at least 3 weeks, till to third passage. These cultures showed a greater cell homogeneity and enrichment in tumor component than original tissues, thus enabling a better discrimination of CNAs and LOH. Especially for hemizygous deletions, primary cultures presented more evident CN losses, typically accompanied by LOH; differently, in original tissues the intensity of these deletions was weaken by normal cell contamination and LOH calls were missed. ccRCC primary cultures are a reliable in vitro model, well-reproducing original tumor genetics and phenotype, potentially useful for future functional approaches

A model of phone call intervention in sensitizing the change of dietary pattern - doi:10.5020/18061230.2010.p136

Directory of Open Access Journals (Sweden)

Eliane Corrêa Chaves

2012-01-01

Full Text Available Objective: To propose a model of phone call intervention for changing dietary patterns and to assess its effectiveness. Method: A study carried out at the Health Promotion School of Medicine, University of São Paulo, with 27 subjects, 3-5 phone calls contacts per user, by means of which were given orientations and interventions on the principles of Cognitive Behavioral Therapy and the Transtheoretical Model on healthy eating. We analyzed the variables weight and body mass index, dietary patterns and overall stage of motivation to change. The data were submitted to analysis of variance with repeated measures at different stages of evaluation: pre-contact, 3rd and 5th phone calls. Results: After intervention, users showed a change in eating behavior in the third contact, and change occurred in weight and BMI in one patient. All findings were not statistically significant. There was improvement in the motivation to acquire new eating habits, also not significant. Conclusion: There was a slight change in feeding behavior, the motivation to change improved for all participants, without, however, have been effective in this type of approach.

A Call-Put Duality for Perpetual American Options

OpenAIRE

Alfonsi, Aurélien; Jourdain, Benjamin

2006-01-01

International audience; It is well known that in models with time-homogeneous local volatility functions and constant interest and dividend rates, the European Put prices are transformed into European Call prices by the simultaneous exchanges of the interest and dividend rates and of the strike and spot price of the underlying. This paper investigates such a Call Put duality for perpetual American options. It turns out that the perpetual American Put price is equal to the perpetual American C...

Error Correction of Measured Unstructured Road Profiles Based on Accelerometer and Gyroscope Data

Directory of Open Access Journals (Sweden)

Jinhua Han

2017-01-01

Full Text Available This paper describes a noncontact acquisition system composed of several time synchronized laser height sensors, accelerometers, gyroscope, and so forth in order to collect the road profiles of vehicle riding on the unstructured roads. A method of correcting road profiles based on the accelerometer and gyroscope data is proposed to eliminate the adverse impacts of vehicle vibration and attitudes change. Because the power spectral density (PSD of gyro attitudes concentrates in the low frequency band, a method called frequency division is presented to divide the road profiles into two parts: high frequency part and low frequency part. The vibration error of road profiles is corrected by displacement data obtained through two times integration of measured acceleration data. After building the mathematical model between gyro attitudes and road profiles, the gyro attitudes signals are separated from low frequency road profile by the method of sliding block overlap based on correlation analysis. The accuracy and limitations of the system have been analyzed, and its validity has been verified by implementing the system on wheeled equipment for road profiles’ measuring of vehicle testing ground. The paper offers an accurate and practical approach to obtaining unstructured road profiles for road simulation test.

Environmental constraints and call evolution in torrent-dwelling frogs.

Science.gov (United States)

Goutte, Sandra; Dubois, Alain; Howard, Samuel D; Marquez, Rafael; Rowley, Jodi J L; Dehling, J Maximilian; Grandcolas, Philippe; Rongchuan, Xiong; Legendre, Frédéric

2016-04-01

Although acoustic signals are important for communication in many taxa, signal propagation is affected by environmental properties. Strong environmental constraints should drive call evolution, favoring signals with greater transmission distance and content integrity in a given calling habitat. Yet, few empirical studies have verified this prediction, possibly due to a shortcoming in habitat characterization, which is often too broad. Here we assess the potential impact of environmental constraints on the evolution of advertisement call in four groups of torrent-dwelling frogs in the family Ranidae. We reconstruct the evolution of calling site preferences, both broadly categorized and at a finer scale, onto a phylogenetic tree for 148 species with five markers (∼3600 bp). We test models of evolution for six call traits for 79 species with regard to the reconstructed history of calling site preferences and estimate their ancestral states. We find that in spite of existing morphological constraints, vocalizations of torrent-dwelling species are most probably constrained by the acoustic specificities of torrent habitats and particularly their high level of ambient noise. We also show that a fine-scale characterization of calling sites allows a better perception of the impact of environmental constraints on call evolution. © 2016 The Author(s). Evolution © 2016 The Society for the Study of Evolution.

Measurement and modeling of nitrogen resonance line profiles from an electrodeless discharge lamp

International Nuclear Information System (INIS)

Wood, D.R.; Skinner, G.B.; Lifshitz, A.

1987-01-01

Experimental profiles of the 1200 A resonance triplet of atomic nitrogen were measured for a variety of operating conditions of an end-on electrodeless lamp, and corresponding absorption curves were calculated. Each source profile was determined by fitting parameters to an empirical two-layer model, then convoluting with the instrumental function for comparison with experimental data. Each three-component profile was fitted with three adjustable parameters: an absorption parameter for each of the two layers and a third absorption parameter to adjust for radiation trapping. Curves of absorption as a function of atom concentration, calculated from these profiles, are very similar to the shock tube calibrations of Thielen and Roth in which a source of similar design has been used

MODELING MULTI-WAVELENGTH PULSE PROFILES OF THE MILLISECOND PULSAR PSR B1821–24

Energy Technology Data Exchange (ETDEWEB)

Du, Yuanjie; Shuai, Ping; Bei, Xiaomin; Chen, Shaolong; Fu, Linzhong; Huang, Liangwei; Lin, Qingqing; Meng, Jing; Wu, Yaojun; Zhang, Hengbin; Zhang, Qian; Zhang, Xinyuan [Qian Xuesen Laboratory of Space Technology, NO. 104, Youyi Road, Haidian District, Beijing 100094 (China); Qiao, Guojun, E-mail: dyj@nao.cas.cn [School of Physics, Peking University, Beijing 100871 (China)

2015-03-10

PSR B1821–24 is a solitary millisecond pulsar that radiates multi-wavelength pulsed photons. It has complex radio, X-ray, and γ-ray pulse profiles with distinct peak phase separations that challenge the traditional caustic emission models. Using the single-pole annular gap model with a suitable magnetic inclination angle (α = 40°) and viewing angle (ζ = 75°), we managed to reproduce its pulse profiles of three wavebands. It is found that the middle radio peak originated from the core gap region at high altitudes, and the other two radio peaks originated from the annular gap region at relatively low altitudes. Two peaks of both X-ray and γ-ray wavebands basically originated from the annular gap region, while the γ-ray emission generated from the core gap region contributes somewhat to the first γ-ray peak. Precisely reproducing the multi-wavelength pulse profiles of PSR B1821–24 enables us to understand emission regions of distinct wavebands and justify pulsar emission models.

Modeling Site Heterogeneity with Posterior Mean Site Frequency Profiles Accelerates Accurate Phylogenomic Estimation.

Science.gov (United States)

Wang, Huai-Chun; Minh, Bui Quang; Susko, Edward; Roger, Andrew J

2018-03-01

Proteins have distinct structural and functional constraints at different sites that lead to site-specific preferences for particular amino acid residues as the sequences evolve. Heterogeneity in the amino acid substitution process between sites is not modeled by commonly used empirical amino acid exchange matrices. Such model misspecification can lead to artefacts in phylogenetic estimation such as long-branch attraction. Although sophisticated site-heterogeneous mixture models have been developed to address this problem in both Bayesian and maximum likelihood (ML) frameworks, their formidable computational time and memory usage severely limits their use in large phylogenomic analyses. Here we propose a posterior mean site frequency (PMSF) method as a rapid and efficient approximation to full empirical profile mixture models for ML analysis. The PMSF approach assigns a conditional mean amino acid frequency profile to each site calculated based on a mixture model fitted to the data using a preliminary guide tree. These PMSF profiles can then be used for in-depth tree-searching in place of the full mixture model. Compared with widely used empirical mixture models with $k$ classes, our implementation of PMSF in IQ-TREE (http://www.iqtree.org) speeds up the computation by approximately $k$/1.5-fold and requires a small fraction of the RAM. Furthermore, this speedup allows, for the first time, full nonparametric bootstrap analyses to be conducted under complex site-heterogeneous models on large concatenated data matrices. Our simulations and empirical data analyses demonstrate that PMSF can effectively ameliorate long-branch attraction artefacts. In some empirical and simulation settings PMSF provided more accurate estimates of phylogenies than the mixture models from which they derive.

Call Center Capacity Planning

DEFF Research Database (Denmark)

Nielsen, Thomas Bang

in order to relate the results to the service levels used in call centers. Furthermore, the generic nature of the approximation is demonstrated by applying it to a system incorporating a dynamic priority scheme. In the last paper Optimization of overflow policies in call centers, overflows between agent......The main topics of the thesis are theoretical and applied queueing theory within a call center setting. Call centers have in recent years become the main means of communication between customers and companies, and between citizens and public institutions. The extensively computerized infrastructure...... in modern call centers allows for a high level of customization, but also induces complicated operational processes. The size of the industry together with the complex and labor intensive nature of large call centers motivates the research carried out to understand the underlying processes. The customizable...

Modelling of the urban wind profile

DEFF Research Database (Denmark)

Gryning, Sven-Erik; Batchvarova, Ekaterina

2008-01-01

Analysis of meteorological measurements from tall masts in rural and urban areas show that the height of the boundary layer influences the wind profile even in the lowest hundreds of meters. A parameterization of the wind profile for the entire boundary layer is formulated with emphasis on the lo...

Modelling the effect of boundary scavenging on Thorium and Protactinium profiles in the ocean

International Nuclear Information System (INIS)

Roy-Barman, M.

2009-01-01

The 'boundary scavenging' box model is a cornerstone of our understanding of the particle-reactive radionuclide fluxes between the open ocean and the ocean margins. However, it does not describe the radionuclide profiles in the water column. Here, I present the transport-reaction equations for radionuclides transported vertically by reversible scavenging on settling particles and laterally by horizontal currents between the margin and the open ocean. Analytical solutions of these equations are compared with existing data. In the Pacific Ocean, the model produces 'almost' linear 230 Th profiles (as observed in the data) despite lateral transport. However, omitting lateral transport biases the 230 Th based particle flux estimates by as much as 50%. 231 Pa profiles are well reproduced in the whole water column of the Pacific Margin and from the surface down to 3000 m in the Pacific subtropical gyre. Enhanced bottom scavenging or inflow of 231 Pa-poor equatorial water may account for the model-data discrepancy below 3000 m. The lithogenic 232 Th is modelled using the same transport parameters as 230 Th but a different source function. The main source of the 232 Th scavenged in the open Pacific is advection from the ocean margin, whereas a net flux of 230 Th produced in the open Pacific is advected and scavenged at the margin, illustrating boundary exchange. In the Arctic Ocean, the model reproduces 230 Th measured profiles that the uni-dimensional scavenging model or the scavenging-ventilation model failed to explain. Moreover, if lateral transport is ignored, the 230 Th based particle settling speed may by underestimated by a factor 4 at the Arctic Ocean margin. The very low scavenging rate in the open Arctic Ocean combined with the enhanced scavenging at the margin accounts for the lack of high 231 Pa/ 230 Th ratio in arctic sediments. (authors)

Calle Blanco

Directory of Open Access Journals (Sweden)

Gonzalo Cerda Brintrup

1988-06-01

Full Text Available Importante arteria, que comunica el sector del puerto con la plaza. Las más imponentes construcciones se sucedían de un modo continuo, encaramándose a ambos lados de la empinada calle. Antes del gran incendio de 1936 grandes casonas de madera destacaban en calle Irarrázabal y en la esquina de ésta con calle Blanco, la más hermosa construcción pertenecía a don Alberto Oyarzún y la casa vecina hacia Blanco era de don Mateo Miserda, limitada por arriba con la casa de don Augusto Van Der Steldt y ésta era seguida de la casa de don David Barrientos provista de cuatro cúpulas en las esquinas y de un amplio corredor en el frontis. Todas estas construcciones de madera fueron destruidas en el gran incendio de 1936.

Analytical models of lateral power devices with arbitrary vertical doping profiles in the drift region

International Nuclear Information System (INIS)

Hua Ting-Ting; Guo Yu-Feng; Yu Ying; Jian Tong; Yao Jia-Fei; Sheu Gene

2013-01-01

By solving the 2D Poisson's equation, analytical models are proposed to calculate the surface potential and electric field distributions of lateral power devices with arbitrary vertical doping profiles. The vertical and the lateral breakdown voltages are formulized to quantify the breakdown characteristic in completely-depleted and partially-depleted cases. A new reduced surface field (RESURF) criterion which can be used in various drift doping profiles is further derived for obtaining the optimal trade-off between the breakdown voltage and the on-resistance. Based on these models and the numerical simulation, the electric field modulation mechanism and the breakdown characteristics of lateral power devices are investigated in detail for the uniform, linear, Gaussian, and some discrete doping profiles along the vertical direction in the drift region. Then, the mentioned vertical doping profiles of these devices with the same geometric parameters are optimized, and the results show that the optimal breakdown voltages and the effective drift doping concentrations of these devices are identical, which are equal to those of the uniform-doped device, respectively. The analytical results of these proposed models are in good agreement with the numerical results and the previous experimental results, confirming the validity of the models presented here. (interdisciplinary physics and related areas of science and technology)

Analytical models of lateral power devices with arbitrary vertical doping profiles in the drift region

Science.gov (United States)

Hua, Ting-Ting; Guo, Yu-Feng; Yu, Ying; Gene, Sheu; Jian, Tong; Yao, Jia-Fei

2013-05-01

By solving the 2D Poisson's equation, analytical models are proposed to calculate the surface potential and electric field distributions of lateral power devices with arbitrary vertical doping profiles. The vertical and the lateral breakdown voltages are formulized to quantify the breakdown characteristic in completely-depleted and partially-depleted cases. A new reduced surface field (RESURF) criterion which can be used in various drift doping profiles is further derived for obtaining the optimal trade-off between the breakdown voltage and the on-resistance. Based on these models and the numerical simulation, the electric field modulation mechanism and the breakdown characteristics of lateral power devices are investigated in detail for the uniform, linear, Gaussian, and some discrete doping profiles along the vertical direction in the drift region. Then, the mentioned vertical doping profiles of these devices with the same geometric parameters are optimized, and the results show that the optimal breakdown voltages and the effective drift doping concentrations of these devices are identical, which are equal to those of the uniform-doped device, respectively. The analytical results of these proposed models are in good agreement with the numerical results and the previous experimental results, confirming the validity of the models presented here.

Five-Factor Model personality profiles of drug users

Directory of Open Access Journals (Sweden)

Crum Rosa M

2008-04-01

Full Text Available Abstract Background Personality traits are considered risk factors for drug use, and, in turn, the psychoactive substances impact individuals' traits. Furthermore, there is increasing interest in developing treatment approaches that match an individual's personality profile. To advance our knowledge of the role of individual differences in drug use, the present study compares the personality profile of tobacco, marijuana, cocaine, and heroin users and non-users using the wide spectrum Five-Factor Model (FFM of personality in a diverse community sample. Method Participants (N = 1,102; mean age = 57 were part of the Epidemiologic Catchment Area (ECA program in Baltimore, MD, USA. The sample was drawn from a community with a wide range of socio-economic conditions. Personality traits were assessed with the Revised NEO Personality Inventory (NEO-PI-R, and psychoactive substance use was assessed with systematic interview. Results Compared to never smokers, current cigarette smokers score lower on Conscientiousness and higher on Neuroticism. Similar, but more extreme, is the profile of cocaine/heroin users, which score very high on Neuroticism, especially Vulnerability, and very low on Conscientiousness, particularly Competence, Achievement-Striving, and Deliberation. By contrast, marijuana users score high on Openness to Experience, average on Neuroticism, but low on Agreeableness and Conscientiousness. Conclusion In addition to confirming high levels of negative affect and impulsive traits, this study highlights the links between drug use and low Conscientiousness. These links provide insight into the etiology of drug use and have implications for public health interventions.

[Bioacoustic of the advertisement call of Ceratophrys cranwelli (Anura: Ceratophryidae)].

Science.gov (United States)

Valetti, Julián Alonso; Salas, Nancy Edith; Martino, Adolfo Ludovico

2013-03-01

The advertisement call plays an important role in the life history of anuran amphibians, mainly during the breeding season. Call features represent an important character to discriminate species, and sound emissions are very effective to assure or reinforce genetic incompatibility, especially in the case of sibling species. Since frogs are ectotherms, acoustic properties of their calls will vary with temperature. In this study, we described the advertisement call of C. cranwelli, quantifying the temperature effect on its components. The acoustic emissions were recorded during 2007 using a DAT record Sony TCD-100 with stereo microphone ECM-MS907 Sony and tape TDK DAT-RGX 60. As males emit their calls floating in temporary ponds, water temperatures were registered after recording the advertisement calls with a digital thermometer TES 1300+/-0.1 degreeC. Altogether, 54 calls from 18 males were analyzed. The temporal variables of each advertisement call were measured using oscillograms and sonograms and the analyses of dominant frequency were performed using a spectrogram. Multiple correlation analysis was used to identify the temperature-dependent acoustic variables and the temperature effect on these variables was quantified using linear regression models. The advertisement call of C. cranwelli consists of a single pulse group. Call duration, Pulse duration and Pulse interval decreased with the temperature, whereas the Pulse rate increased with temperature. The temperature-dependent variables were standardized at 25 degreeC according to the linear regression model obtained. The acoustic variables that were correlated with the temperature are the variables which emissions depend on laryngeal muscles and the temperature constraints the contractile properties of muscles. Our results indicated that temperature explains an important fraction of the variability in some acoustic variables (79% in the Pulse rate), and demonstrated the importance of considering the effect of

Alterations of urinary metabolite profile in model diabetic nephropathy

Energy Technology Data Exchange (ETDEWEB)

Stec, Donald F. [Vanderbilt Institute of Chemical Biology, Vanderbilt University Medical Center, Nashville, TN 37232 (United States); Wang, Suwan; Stothers, Cody [Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 (United States); Avance, Josh [Berea College, 1916 CPO, Berea, KY 40404 (United States); Denson, Deon [Choctaw Central High School, Philadelphia, MS 39350 (United States); Harris, Raymond [Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 (United States); Voziyan, Paul, E-mail: paul.voziyan@vanderbilt.edu [Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 (United States)

2015-01-09

Highlights: • {sup 1}H NMR spectroscopy was employed to study urinary metabolite profile in diabetic mouse models. • Mouse urinary metabolome showed major changes that are also found in human diabetic nephropathy. • These models can be new tools to study urinary biomarkers that are relevant to human disease. - Abstract: Countering the diabetes pandemic and consequent complications, such as nephropathy, will require better understanding of disease mechanisms and development of new diagnostic methods. Animal models can be versatile tools in studies of diabetic renal disease when model pathology is relevant to human diabetic nephropathy (DN). Diabetic models using endothelial nitric oxide synthase (eNOS) knock-out mice develop major renal lesions characteristic of human disease. However, it is unknown whether they can also reproduce changes in urinary metabolites found in human DN. We employed Type 1 and Type 2 diabetic mouse models of DN, i.e. STZ-eNOS{sup −/−} C57BLKS and eNOS{sup −/−} C57BLKS db/db, with the goal of determining changes in urinary metabolite profile using proton nuclear magnetic resonance (NMR). Six urinary metabolites with significantly lower levels in diabetic compared to control mice have been identified. Specifically, major changes were found in metabolites from tricarboxylic acid (TCA) cycle and aromatic amino acid catabolism including 3-indoxyl sulfate, cis-aconitate, 2-oxoisocaproate, N-phenyl-acetylglycine, 4-hydroxyphenyl acetate, and hippurate. Levels of 4-hydroxyphenyl acetic acid and hippuric acid showed the strongest reverse correlation to albumin-to-creatinine ratio (ACR), which is an indicator of renal damage. Importantly, similar changes in urinary hydroxyphenyl acetate and hippurate were previously reported in human renal disease. We demonstrated that STZ-eNOS{sup −/−} C57BLKS and eNOS{sup −/−} C57BLKS db/db mouse models can recapitulate changes in urinary metabolome found in human DN and therefore can be

Alterations of urinary metabolite profile in model diabetic nephropathy

International Nuclear Information System (INIS)

Stec, Donald F.; Wang, Suwan; Stothers, Cody; Avance, Josh; Denson, Deon; Harris, Raymond; Voziyan, Paul

2015-01-01

Highlights: • 1 H NMR spectroscopy was employed to study urinary metabolite profile in diabetic mouse models. • Mouse urinary metabolome showed major changes that are also found in human diabetic nephropathy. • These models can be new tools to study urinary biomarkers that are relevant to human disease. - Abstract: Countering the diabetes pandemic and consequent complications, such as nephropathy, will require better understanding of disease mechanisms and development of new diagnostic methods. Animal models can be versatile tools in studies of diabetic renal disease when model pathology is relevant to human diabetic nephropathy (DN). Diabetic models using endothelial nitric oxide synthase (eNOS) knock-out mice develop major renal lesions characteristic of human disease. However, it is unknown whether they can also reproduce changes in urinary metabolites found in human DN. We employed Type 1 and Type 2 diabetic mouse models of DN, i.e. STZ-eNOS −/− C57BLKS and eNOS −/− C57BLKS db/db, with the goal of determining changes in urinary metabolite profile using proton nuclear magnetic resonance (NMR). Six urinary metabolites with significantly lower levels in diabetic compared to control mice have been identified. Specifically, major changes were found in metabolites from tricarboxylic acid (TCA) cycle and aromatic amino acid catabolism including 3-indoxyl sulfate, cis-aconitate, 2-oxoisocaproate, N-phenyl-acetylglycine, 4-hydroxyphenyl acetate, and hippurate. Levels of 4-hydroxyphenyl acetic acid and hippuric acid showed the strongest reverse correlation to albumin-to-creatinine ratio (ACR), which is an indicator of renal damage. Importantly, similar changes in urinary hydroxyphenyl acetate and hippurate were previously reported in human renal disease. We demonstrated that STZ-eNOS −/− C57BLKS and eNOS −/− C57BLKS db/db mouse models can recapitulate changes in urinary metabolome found in human DN and therefore can be useful new tools in

Modeling the effect of dune sorting on the river long profile

Science.gov (United States)

Blom, A.

2012-12-01

River dunes, which occur in low slope sand bed and sand-gravel bed rivers, generally show a downward coarsening pattern due to grain flows down their avalanche lee faces. These grain flows cause coarse particles to preferentially deposit at lower elevations of the lee face, while fines show a preference for its upper elevations. Before considering the effect of this dune sorting mechanism on the river long profile, let us first have a look at some general trends along the river profile. Tributaries increasing the river's water discharge in streamwise direction also cause a streamwise increase in flow depth. As under subcritical conditions mean dune height generally increases with increasing flow depth, the dune height shows a streamwise increase, as well. This means that also the standard deviation of bedform height increases in streamwise direction, as in earlier work it was found that the standard deviation of bedform height linearly increases with an increasing mean value of bedform height. As a result of this streamwise increase in standard deviation of dune height, the above-mentioned dune sorting then results in a loss of coarse particles to the lower elevations of the bed that are less and even rarely exposed to the flow. This loss of coarse particles to lower elevations thus increases the rate of fining in streamwise direction. As finer material is more easily transported downstream than coarser material, a smaller bed slope is required to transport the same amount of sediment downstream. This means that dune sorting adds to river profile concavity, compared to the combined effect of abrasion, selective transport and tributaries. A Hirano-type mass conservation model is presented that deals with dune sorting. The model includes two active layers: a bedform layer representing the sediment in the bedforms and a coarse layer representing the coarse and less mobile sediment underneath migrating bedforms. The exposure of the coarse layer is governed by the rate

Modeling of Thickness and Profile Uniformity of Thermally Sprayed Coatings Deposited on Cylinders

Science.gov (United States)

Yanjun, Zhang; Wenbo, Li; Dayu, Li; Jinkun, Xiao; Chao, Zhang

2018-02-01

In thermal spraying processes, kinematic parameters of the robot play a decisive role in the coating thickness and profile. In this regard, some achievements have been made to optimize the spray trajectory on flat surfaces. However, few reports have focused on nonholonomic or variable-curvature cylindrical surfaces. The aim of this study is to investigate the correlation between the coating profile, coating thickness, and scanning step, which is determined by the radius of curvature and scanning angle. A mathematical simulation model was developed to predict the thickness of thermally sprayed coatings. Experiments were performed on cylinders with different radiuses of curvature to evaluate the predictive ability of the model.

Data description and quality assessment of ionospheric electron density profiles for ARPA modeling project. Technical report

International Nuclear Information System (INIS)

Conkright, R.O.

1977-03-01

This report presents a description of the automated method used to produce electron density (N(h)) profiles from ionograms recorded on 35mm film and an assessment of the resulting data base. A large data base of about 30,000 profiles was required for an ionospheric modeling project. This motivated a search for an automated method of producing profiles. The automated method used is fully described, the resulting data are given a quality grade, and the noon and midnight profiles are presented. Selected portions of this data base are compared with profiles produced by the standard profiling method in use by the Environmental Data Service at Boulder, Colorado

Metabolic profile in different cathegories of diary cowst

OpenAIRE

Ulchar Igor; Celeska Irena; Ilievska Ksenija; Mitrov Dine; Dzhadzhovski Igor

2008-01-01

Knowing the values of the metabolic profile is important for prevention of so-called "production diseases" which have significant negative impact on the milk production. The aim of these investigations was determination of the metabolic profile and its referent values in the diary cows in several farms. Investigations included four categories of diary cows: pregnant heifers, cows in early lactation, cows in late lactation and dry cows. Discussion explains both significant differences of value...

Visual Modelling of Data Warehousing Flows with UML Profiles

Science.gov (United States)

Pardillo, Jesús; Golfarelli, Matteo; Rizzi, Stefano; Trujillo, Juan

Data warehousing involves complex processes that transform source data through several stages to deliver suitable information ready to be analysed. Though many techniques for visual modelling of data warehouses from the static point of view have been devised, only few attempts have been made to model the data flows involved in a data warehousing process. Besides, each attempt was mainly aimed at a specific application, such as ETL, OLAP, what-if analysis, data mining. Data flows are typically very complex in this domain; for this reason, we argue, designers would greatly benefit from a technique for uniformly modelling data warehousing flows for all applications. In this paper, we propose an integrated visual modelling technique for data cubes and data flows. This technique is based on UML profiling; its feasibility is evaluated by means of a prototype implementation.

Primitive entertainment prank calls in the work of counseling psychologist on Children helpline

Directory of Open Access Journals (Sweden)

I.A. Geronimus

2014-08-01

Full Text Available We explore the challenges faced by counseling psychologist when working at the Children's Helpline in cases of prank calls. The category of prank calls include such calls, when the caller asks the psychologist to discuss the imaginary situation, or do not formulate a query at all. On the basis of empirical data, we revealed the main varieties of such calls: call jokes, fantasy calls, intrusive calls, insulting calls, prank calls, calls of a sexual nature, dating calls. We explore the possible motivations of children and adolescents, entertaining by phone calls: experimentation with new social roles, expression of negative emotions, cognitive motivation, etc. We show the principles and strategies of counselors of Children's helpline working with this type of calls: they are based on cultural-historical psychology ideas and V. Satir communicative styles model.

Inverse modeling of FIB milling by dose profile optimization

International Nuclear Information System (INIS)

Lindsey, S.; Waid, S.; Hobler, G.; Wanzenböck, H.D.; Bertagnolli, E.

2014-01-01

FIB technologies possess a unique ability to form topographies that are difficult or impossible to generate with binary etching through typical photo-lithography. The ability to arbitrarily vary the spatial dose distribution and therefore the amount of milling opens possibilities for the production of a wide range of functional structures with applications in biology, chemistry, and optics. However in practice, the realization of these goals is made difficult by the angular dependence of the sputtering yield and redeposition effects that vary as the topography evolves. An inverse modeling algorithm that optimizes dose profiles, defined as the superposition of time invariant pixel dose profiles (determined from the beam parameters and pixel dwell times), is presented. The response of the target to a set of pixel dwell times in modeled by numerical continuum simulations utilizing 1st and 2nd order sputtering and redeposition, the resulting surfaces are evaluated with respect to a target topography in an error minimization routine. Two algorithms for the parameterization of pixel dwell times are presented, a direct pixel dwell time method, and an abstracted method that uses a refineable piecewise linear cage function to generate pixel dwell times from a minimal number of parameters. The cage function method demonstrates great flexibility and efficiency as compared to the direct fitting method with performance enhancements exceeding ∼10× as compared to direct fitting for medium to large simulation sets. Furthermore, the refineable nature of the cage function enables solutions to adapt to the desired target function. The optimization algorithm, although working with stationary dose profiles, is demonstrated to be applicable also outside the quasi-static approximation. Experimental data confirms the viability of the solutions for 5 × 7 μm deep lens like structures defined by 90 pixel dwell times

Investigation on equatorial ionospheric profiles and IRI model

International Nuclear Information System (INIS)

Adeniyi, J.O.

1996-01-01

Ionospheric profiles below the F2 peak ionisation density are compared with those of the International Reference Ionosphere (IRI). The data used are those of Ibadan (Lat. 7.4 deg N, Long. 3.9 E). The IRI model gives a much thinner bottomside F region ionisation density than what is observed experimentally, in winter; both at high and low solar activity. Similar departures are observed in the summer of both solar epoch but on a reduced scale. The closet agreement occurs during the March equinox of high solar activity. (author). 3 refs, 4 figs

Elucidation of xenobiotic metabolism pathways in human skin and human skin models by proteomic profiling.

Directory of Open Access Journals (Sweden)

Sven van Eijl

Full Text Available BACKGROUND: Human skin has the capacity to metabolise foreign chemicals (xenobiotics, but knowledge of the various enzymes involved is incomplete. A broad-based unbiased proteomics approach was used to describe the profile of xenobiotic metabolising enzymes present in human skin and hence indicate principal routes of metabolism of xenobiotic compounds. Several in vitro models of human skin have been developed for the purpose of safety assessment of chemicals. The suitability of these epidermal models for studies involving biotransformation was assessed by comparing their profiles of xenobiotic metabolising enzymes with those of human skin. METHODOLOGY/PRINCIPAL FINDINGS: Label-free proteomic analysis of whole human skin (10 donors was applied and analysed using custom-built PROTSIFT software. The results showed the presence of enzymes with a capacity for the metabolism of alcohols through dehydrogenation, aldehydes through dehydrogenation and oxidation, amines through oxidation, carbonyls through reduction, epoxides and carboxylesters through hydrolysis and, of many compounds, by conjugation to glutathione. Whereas protein levels of these enzymes in skin were mostly just 4-10 fold lower than those in liver and sufficient to support metabolism, the levels of cytochrome P450 enzymes were at least 300-fold lower indicating they play no significant role. Four epidermal models of human skin had profiles very similar to one another and these overlapped substantially with that of whole skin. CONCLUSIONS/SIGNIFICANCE: The proteomics profiling approach was successful in producing a comprehensive analysis of the biotransformation characteristics of whole human skin and various in vitro skin models. The results show that skin contains a range of defined enzymes capable of metabolising different classes of chemicals. The degree of similarity of the profiles of the in vitro models indicates their suitability for epidermal toxicity testing. Overall, these

Behavioral Preferences for Individual Securities : The Case for Call Warrants and Call Options

NARCIS (Netherlands)

Ter Horst, J.R.; Veld, C.H.

2002-01-01

Since 1998, large investment banks have flooded the European capital markets with issues of call warrants.This has led to a unique situation in the Netherlands, where now call warrants, traded on the stock exchange, and long-term call options, traded on the options exchange, exist.Both entitle their

A stable route to high-{beta}{sub p} plasmas with non-monotonic q-profiles

Energy Technology Data Exchange (ETDEWEB)

Soeldner, F X; Baranov, Y; Bhatnagar, V P; Bickley, A J; Challis, C D; Fischer, B; Gormezano, C; Huysmans, G T.A.; Kerner, W; Rimini, F; Sips, A C.C.; Springmann, R; Taroni, A [Commission of the European Communities, Abingdon (United Kingdom). JET Joint Undertaking; Goedbloed, J P; Holties, H A [Institute for Plasmas Physics, Nieuwegein (Netherlands); Parail, V V; Pereverzev, G V [Kurchatov Institute of Atomic Energy, Moscow (Russian Federation)

1994-07-01

Steady-state operation of tokamak reactors seems feasible in so-called Advanced Scenarios with high bootstrap current in high-beta{sub p} operation. The stabilization of such discharges with noninductive profile control will be attempted on JET in pursuit of previous high bootstrap current studies. Results of modelling studies of full noninductive current drive scenarios in JET and ITER are presented. Fast Waves (FW), Lower Hybrid (LH) Waves and Neutral Beam Injection (NBI) are used for heating and current drive, alternatively or in combination. A stable route to nonmonotonic q-profiles has been found with a specific ramp-up scenario which combines LH-current drive (LHCD) and a fast Ohmic ramp-up. A hollow current profile with deep shear reversal over the whole central region is thereby formed in an early low-beta phase and frozen in by additional heating. (authors). 5 refs., 4 figs.

Development of a procedure to model high-resolution wind profiles from smoothed or low-frequency data

Science.gov (United States)

Camp, D. W.

1977-01-01

The derivation of simulated Jimsphere wind profiles from low-frequency rawinsonde data and a generated set of white noise data are presented. A computer program is developed to model high-resolution wind profiles based on the statistical properties of data from the Kennedy Space Center, Florida. Comparison of the measured Jimsphere data, rawinsonde data, and the simulated profiles shows excellent agreement.

Fractal Analysis of Rock Joint Profiles

Science.gov (United States)

Audy, Ondřej; Ficker, Tomáš

2017-10-01

Surface reliefs of rock joints are analyzed in geotechnics when shear strength of rocky slopes is estimated. The rock joint profiles actually are self-affine fractal curves and computations of their fractal dimensions require special methods. Many papers devoted to the fractal properties of these profiles were published in the past but only a few of those papers employed a convenient computational method that would have guaranteed a sound value of that dimension. As a consequence, anomalously low dimensions were presented. This contribution deals with two computational modifications that lead to sound fractal dimensions of the self-affine rock joint profiles. These are the modified box-counting method and the modified yard-stick method sometimes called the compass method. Both these methods are frequently applied to self-similar fractal curves but the self-affine profile curves due to their self-affine nature require modified computational procedures implemented in computer programs.

Study on Rail Profile Optimization Based on the Nonlinear Relationship between Profile and Wear Rate

Directory of Open Access Journals (Sweden)

Jianxi Wang

2017-01-01

Full Text Available This paper proposes a rail profile optimization method that takes account of wear rate within design cycle so as to minimize rail wear at the curve in heavy haul railway and extend the service life of rail. Taking rail wear rate as the object function, the vertical coordinate of rail profile at range optimization as independent variable, and the geometric characteristics and grinding depth of rail profile as constraint conditions, the support vector machine regression theory was used to fit the nonlinear relationship between rail profile and its wear rate. Then, the profile optimization model was built. Based on the optimization principle of genetic algorithm, the profile optimization model was solved to achieve the optimal rail profile. A multibody dynamics model was used to check the dynamic performance of carriage running on optimal rail profile. The result showed that the average relative error of support vector machine regression model remained less than 10% after a number of training processes. The dynamic performance of carriage running on optimized rail profile met the requirements on safety index and stability. The wear rate of optimized profile was lower than that of standard profile by 5.8%; the allowable carrying gross weight increased by 12.7%.

Classification of 'healthier' and 'less healthy' supermarket foods by two Australasian nutrient profiling models.

Science.gov (United States)

Eyles, Helen; Gorton, Delvina; Ni Mhurchu, Cliona

2010-09-10

To determine whether a modified version of the Heart Foundation Tick (MHFT) nutrient profiling model appropriately classifies supermarket foods to endorse its use for identifying 'healthier' products eligible for promotion in a supermarket intervention trial. Top-selling products (n=550) were selected from an existing supermarket nutrient composition database. Percentage of products classified as 'healthier' by the MHFT and a modified comparator model (Food Standards Australia New Zealand; MFSANZ) were calculated. Percentage agreement, consistency (kappa statistic), and average nutrient values were assessed overall, and across seven food groups. The MHFT model categorised 16% fewer products as 'healthier' than the MFSANZ model. Agreement and consistency between models were 72% and kappa=0.46 (P=0.00), respectively. For both models, 'healthier' products were on average lower in energy, protein, saturated fat, sugar, and sodium than their 'less healthy' counterparts. The MHFT nutrient profiling model categorised regularly purchased supermarket foods similarly to the MFSANZ model, and both appear to distinguish appropriately between 'healthier' and 'less healthy' options. Therefore, both models have the potential to appropriately identify 'healthier' foods for promotion and positively influence food choices.

A note on profit maximization and monotonicity for inbound call centers

NARCIS (Netherlands)

Koole, G.M.; Pot, S.A.

2011-01-01

We consider an inbound call center with a fixed reward per call and communication and agent costs. By controlling the number of lines and the number of agents, we can maximize the profit. Abandonments are included in our performance model. Monotonicity results for the maximization problem are

Modelling of composition and stress profiles in low temperature surface engineered stainless steel

DEFF Research Database (Denmark)

Jespersen, Freja Nygaard; Hattel, Jesper Henri; Somers, Marcel A. J.

2015-01-01

temperature, time and gas composition is a prerequisite for targeted process optimization. A realistic model to simulate the developing case has to take the following influences on composition and stress into account: - a concentration dependent diffusion coefficient - trapping of nitrogen by chromium atoms...... stresses are introduced in the developing case, arising from the volume expansion that accompanies the dissolution of high interstitial contents in expanded austenite. Modelling of the composition and stress profiles developing during low temperature surface engineering from the processing parameters...... - the effect of residual stress on diffusive flux - the effect of residual stress on solubility of interstitials - plastic accommodation of residual stress. The effect of all these contributions on composition and stress profiles will be addressed....

Calling vs Receiving Party Pays: Market Penetration and the Importance of the Call Externality

OpenAIRE

Tommaso Majer; Michele Pistollato

2010-01-01

In this paper we study how the access price affects the choice of the tariff regime taken by the network operators. We show that for high values of the access price, that is taken as a parameter by the firms, networks decide to charge only the callers. Otherwise, for low values of the access charge, networks charge also the receivers. Moreover, we compare market penetration and total welfare between the two price regimes. Our model suggests that, for high values of call externality, market pe...

Calling vs receiving party pays : market penetration and the importance of the call externality

OpenAIRE

Majer, Tommaso

2011-01-01

In this paper we study how the access price affects the choice of the tariff regime taken by the network operators. We show that for high values of the access price, that is taken as a parameter by the firms, networks decide to charge only the callers. Otherwise, for low values of the access charge, networks charge also the receivers. Moreover, we compare market penetration and total welfare between the two price regimes. Our model suggests that, for high values of call externality, market pe...

Call mimicry by eastern towhees and its significance in relation to auditory learning

Science.gov (United States)

Jon S. Greenlaw; Clifford E. Shackelford; Raymond E. Brown

1998-01-01

The authors document cases of eastern towhees (Pipilo erythrophthalmus) using mimicked alarm calls from three presumptive models (blue jay (Cyanocitta cristata), brown thrasher (Toxostoma rufum), and American robin (Turdus migratorius)). In four instances, male towhees employed heterospecific calls without substitution in their own call repertoires. Three birds (New...

Satellite-derived vertical profiles of temperature and dew point for mesoscale weather forecast

Science.gov (United States)

Masselink, Thomas; Schluessel, P.

1995-12-01

Weather forecast-models need spatially high resolutioned vertical profiles of temperature and dewpoint for their initialisation. These profiles can be supplied by a combination of data from the Tiros-N Operational Vertical Sounder (TOVS) and the imaging Advanced Very High Resolution Radiometer (AVHRR) on board the NOAA polar orbiting sate!- lites. In cloudy cases the profiles derived from TOVS data only are of insufficient accuracy. The stanthrd deviations from radiosonde ascents or numerical weather analyses likely exceed 2 K in temperature and 5Kin dewpoint profiles. It will be shown that additional cloud information as retrieved from AVHIRR allows a significant improvement in theaccuracy of vertical profiles. The International TOVS Processing Package (ITPP) is coupled to an algorithm package called AVHRR Processing scheme Over cLouds, Land and Ocean (APOLLO) where parameters like cloud fraction and cloud-top temperature are determined with higher accuracy than obtained from TOVS retrieval alone. Furthermore, a split-window technique is applied to the cloud-free AVHRR imagery in order to derive more accurate surface temperatures than can be obtained from the pure TOVS retrieval. First results of the impact of AVHRR cloud detection on the quality of the profiles are presented. The temperature and humidity profiles of different retrieval approaches are validated against analyses of the European Centre for Medium-Range Weatherforecasts.

Modelling the effect of boundary scavenging on Thorium and Protactinium profiles in the ocean

Directory of Open Access Journals (Sweden)

M. Roy-Barman

2009-12-01

Full Text Available The "boundary scavenging" box model is a cornerstone of our understanding of the particle-reactive radionuclide fluxes between the open ocean and the ocean margins. However, it does not describe the radionuclide profiles in the water column. Here, I present the transport-reaction equations for radionuclides transported vertically by reversible scavenging on settling particles and laterally by horizontal currents between the margin and the open ocean. Analytical solutions of these equations are compared with existing data. In the Pacific Ocean, the model produces "almost" linear ²³⁰Th profiles (as observed in the data despite lateral transport. However, omitting lateral transport biaises the ²³⁰Th based particle flux estimates by as much as 50%. ²³¹Pa profiles are well reproduced in the whole water column of the Pacific Margin and from the surface down to 3000 m in the Pacific subtropical gyre. Enhanced bottom scavenging or inflow of ²³¹Pa-poor equatorial water may account for the model-data discrepancy below 3000 m. The lithogenic ²³²Th is modelled using the same transport parameters as ²³⁰Th but a different source function. The main source of the ²³²Th scavenged in the open Pacific is advection from the ocean margin, whereas a net flux of ²³⁰Th produced in the open Pacific is advected and scavenged at the margin, illustrating boundary exchange. In the Arctic Ocean, the model reproduces ²³⁰Th measured profiles that the uni-dimensional scavenging model or the scavenging-ventilation model failed to explain. Moreover, if lateral transport is ignored, the ²³⁰Th based particle settling speed may by underestimated by a factor 4 at the Arctic Ocean margin. The very low scavenging rate in the open Arctic Ocean combined with the enhanced scavenging at the margin accounts for the lack of high ²³¹Pa/²³⁰Th ratio in arctic

A Comparison of Thermal Models for Temperature Profiles in Gas-Lift Wells

Directory of Open Access Journals (Sweden)

Langfeng Mu

2018-02-01

Full Text Available Gas lift is a simple, reliable artificial lift method which is frequently used in offshore oil field developments. In order to enhance the efficiency of production by gas lift, it is vital to exactly predict the distribution of temperature-field for fluid within the wellbore. A new mechanistic model is developed for computing flowing fluid temperature profiles in both conduits simultaneously for a continuous-flow gas-lift operation. This model assumes steady heat transfer in the formation, as well as steady heat transfer in the conduits. A micro-units discrete from the wellbore, whose heat transfer process is analyzed and whose heat transfer equation is set up according to the law of conservation of energy. A simplified algebraic solution to our model is conducted to analyze the temperature profile. Sensitivity analysis was conducted with the new model. The results indicate that mass flow rate of oil and the tubing overall heat transfer coefficient are the main factors that influence the temperature distribution inside the tubing and that the mass flow rate of oil is the main factor affecting temperature distribution in the annulus. Finally, the new model was tested in three various wells and compared with other models. The results showed that the new model is more accurate and provides significant references for temperature prediction in gas lift well.

Microarray profiling shows distinct differences between primary tumors and commonly used preclinical models in hepatocellular carcinoma

International Nuclear Information System (INIS)

Wang, Weining; Iyer, N. Gopalakrishna; Tay, Hsien Ts’ung; Wu, Yonghui; Lim, Tony K. H.; Zheng, Lin; Song, In Chin; Kwoh, Chee Keong; Huynh, Hung; Tan, Patrick O. B.; Chow, Pierce K. H.

2015-01-01

Despite advances in therapeutics, outcomes for hepatocellular carcinoma (HCC) remain poor and there is an urgent need for efficacious systemic therapy. Unfortunately, drugs that are successful in preclinical studies often fail in the clinical setting, and we hypothesize that this is due to functional differences between primary tumors and commonly used preclinical models. In this study, we attempt to answer this question by comparing tumor morphology and gene expression profiles between primary tumors, xenografts and HCC cell lines. Hep G2 cell lines and tumor cells from patient tumor explants were subcutaneously (ectopically) injected into the flank and orthotopically into liver parenchyma of Mus Musculus SCID mice. The mice were euthanized after two weeks. RNA was extracted from the tumors, and gene expression profiling was performed using the Gene Chip Human Genome U133 Plus 2.0. Principal component analyses (PCA) and construction of dendrograms were conducted using Partek genomics suite. PCA showed that the commonly used HepG2 cell line model and its xenograft counterparts were vastly different from all fresh primary tumors. Expression profiles of primary tumors were also significantly divergent from their counterpart patient-derived xenograft (PDX) models, regardless of the site of implantation. Xenografts from the same primary tumors were more likely to cluster together regardless of site of implantation, although heat maps showed distinct differences in gene expression profiles between orthotopic and ectopic models. The data presented here challenges the utility of routinely used preclinical models. Models using HepG2 were vastly different from primary tumors and PDXs, suggesting that this is not clinically representative. Surprisingly, site of implantation (orthotopic versus ectopic) resulted in limited impact on gene expression profiles, and in both scenarios xenografts differed significantly from the original primary tumors, challenging the long

Modeling of gas flow and deposition profile in HWCVD processes

Energy Technology Data Exchange (ETDEWEB)

Pflug, Andreas; Höfer, Markus; Harig, Tino; Armgardt, Markus; Britze, Chris; Siemers, Michael; Melzig, Thomas; Schäfer, Lothar

2015-11-30

Hot wire chemical vapor deposition (HWCVD) is a powerful technology for deposition of high quality films on large area, where drawbacks of plasma based technology such as defect generation by ion bombardment and high equipment costs are omitted. While processes for diamond coatings using H{sub 2} and CH{sub 4} as precursor have been investigated in detail since 1990 and have been transferred to industry, research also focuses on silicon based coatings with H{sub 2}, SiH{sub 4} and NH{sub 3} as process gases. HWCVD of silicon based coatings is a promising alternative for state-of-the-art radiofrequency-plasma enhanced chemical vapor deposition reactors. The film formation in HWCVD results from an interaction of several concurrent chemical reactions such as gas phase chemistry, film deposition, abstraction of surplus hydrogen bonds and etching by atomic hydrogen. Since there is no easy relation between process parameters and resulting deposition profiles, substantial experimental effort is required to optimize the process for a given film specification and the desired film uniformity. In order to obtain a deeper understanding of the underlying mechanisms and to enable an efficient way of process optimization, simulation methods come into play. While diamond deposition occurs at pressures in the range of several kPa HWCVD deposition of Si based coatings operates at pressures in the 0.1–30 Pa range. In this pressure regime, particle based simulation methods focused on solving the Boltzmann equation are computationally feasible. In comparison to computational fluid dynamics this yields improved accuracy even near small gaps or orifices, where characteristic geometric dimensions approach the order of the mean free path of gas molecules. At Fraunhofer IST, a parallel implementation of the Direct Simulation Monte Carlo (DSMC) method extended by a reactive wall chemistry model is developed. To demonstrate the feasibility of three-dimensional simulation of HWCVD processes

TargetNet: a web service for predicting potential drug-target interaction profiling via multi-target SAR models

Science.gov (United States)

Yao, Zhi-Jiang; Dong, Jie; Che, Yu-Jing; Zhu, Min-Feng; Wen, Ming; Wang, Ning-Ning; Wang, Shan; Lu, Ai-Ping; Cao, Dong-Sheng

2016-05-01

Drug-target interactions (DTIs) are central to current drug discovery processes and public health fields. Analyzing the DTI profiling of the drugs helps to infer drug indications, adverse drug reactions, drug-drug interactions, and drug mode of actions. Therefore, it is of high importance to reliably and fast predict DTI profiling of the drugs on a genome-scale level. Here, we develop the TargetNet server, which can make real-time DTI predictions based only on molecular structures, following the spirit of multi-target SAR methodology. Naïve Bayes models together with various molecular fingerprints were employed to construct prediction models. Ensemble learning from these fingerprints was also provided to improve the prediction ability. When the user submits a molecule, the server will predict the activity of the user's molecule across 623 human proteins by the established high quality SAR model, thus generating a DTI profiling that can be used as a feature vector of chemicals for wide applications. The 623 SAR models related to 623 human proteins were strictly evaluated and validated by several model validation strategies, resulting in the AUC scores of 75-100 %. We applied the generated DTI profiling to successfully predict potential targets, toxicity classification, drug-drug interactions, and drug mode of action, which sufficiently demonstrated the wide application value of the potential DTI profiling. The TargetNet webserver is designed based on the Django framework in Python, and is freely accessible at http://targetnet.scbdd.com.

TargetNet: a web service for predicting potential drug-target interaction profiling via multi-target SAR models.

Science.gov (United States)

Yao, Zhi-Jiang; Dong, Jie; Che, Yu-Jing; Zhu, Min-Feng; Wen, Ming; Wang, Ning-Ning; Wang, Shan; Lu, Ai-Ping; Cao, Dong-Sheng

2016-05-01

Drug-target interactions (DTIs) are central to current drug discovery processes and public health fields. Analyzing the DTI profiling of the drugs helps to infer drug indications, adverse drug reactions, drug-drug interactions, and drug mode of actions. Therefore, it is of high importance to reliably and fast predict DTI profiling of the drugs on a genome-scale level. Here, we develop the TargetNet server, which can make real-time DTI predictions based only on molecular structures, following the spirit of multi-target SAR methodology. Naïve Bayes models together with various molecular fingerprints were employed to construct prediction models. Ensemble learning from these fingerprints was also provided to improve the prediction ability. When the user submits a molecule, the server will predict the activity of the user's molecule across 623 human proteins by the established high quality SAR model, thus generating a DTI profiling that can be used as a feature vector of chemicals for wide applications. The 623 SAR models related to 623 human proteins were strictly evaluated and validated by several model validation strategies, resulting in the AUC scores of 75-100 %. We applied the generated DTI profiling to successfully predict potential targets, toxicity classification, drug-drug interactions, and drug mode of action, which sufficiently demonstrated the wide application value of the potential DTI profiling. The TargetNet webserver is designed based on the Django framework in Python, and is freely accessible at http://targetnet.scbdd.com .

Structural acoustics model of the violin radiativity profile.

Science.gov (United States)

Bissinger, George

2008-12-01

Violin radiativity profiles are dominated by the Helmholtz-like A0 cavity mode ( approximately 280 Hz), first corpus bending modes B1(-) and B1(+) ( approximately 500 Hz), and BH and bridge-filter peaks ( approximately 2.4 kHz and approximately 3.5 kHz, respectively), with falloff above approximately 4 kHz. The B1 modes-dependent on two low-lying free-plate modes--are proposed to excite A0 via coupling to B1-driven in-phase f-hole volume flows. VIOCADEAS data show that A0 radiativity increases primarily as A0-B1(-) frequency difference decreases, consistent with Meinel's 1937 experiment for too-thick/too-thin plate thicknesses, plus sound post removal and violin octet baritone results. The vibration-->acoustic energy filter, F(RAD), computed from shape-material-independent radiation and total damping, peaks at the critical frequency f(crit), estimated from a free-plate mode by analogy to flat-plate bending. Experimentally, f(crit) decreased as this plate mode (and B1(+)) frequency increased. Simulations show that increasing plate thicknesses lowers f(crit), reduces F(RAD), and moves the spectral balance toward lower frequencies. Incorporating string-->corpus filters (including bridge versus bridge-island impedances) provides a model for overall violin radiativity. This model-with B1 and A0-B1 couplings, and f(crit) (computed from a free-plate mode important to B1) strongly affecting the lowest and highest parts of the radiativity profile-substantiates prior empirical B1--sound quality linkages.

Optimization of Overflow Policies in Call Centers

DEFF Research Database (Denmark)

Koole, G.M.; Nielsen, B.F.; Nielsen, T.B.

2015-01-01

. A Markov decision chain is used to determine the optimal policy. This policy outperforms considerably the ones used most often in practice, which use a fixed threshold. The present method can be used also for other call-center models and other situations where performance is based on actual waiting times...

Velocity dispersion profiles of clusters of galaxies

International Nuclear Information System (INIS)

Struble, M.F.

1979-01-01

Velocity dispersion as a function of radius, called sigma/sub ls/ profiles, is presented for 13 clusters of galaxies having > or =30 radial velocities from both published and unpublished lists. A list of probable new members and possible outlying members for these clusters is also given. chi 2 and Kolmogoroff--Smirnoff one-sample tests for the goodness of fit of power laws to portions of the profiles indicate two significant structures in some profiles: (1) a local minimum corresponding to the local minimum noted in surface density or surface brightness profiles, and (2) a decrease in sigma/sub ls/ toward the cores. Both of these features are discussed in terms of a comparison with Wielen's N-body simulations. The sigma/sub ls/ profiles are placed in a new classification scheme which lends itself to interpreting clusters in a dynamical age sequence. The velocity field of galaxies at large distances from cluster centers is also discussed

Social learning: medical student perceptions of geriatric house calls.

Science.gov (United States)

Abbey, Linda; Willett, Rita; Selby-Penczak, Rachel; McKnight, Roberta

2010-01-01

Bandura's social learning theory provides a useful conceptual framework to understand medical students' perceptions of a house calls experience at Virginia Commonwealth University School of Medicine. Social learning and role modeling reflect Liaison Committee on Medical Education guidelines for "Medical schools (to) ensure that the learning environment for medical students promotes the development of explicit and appropriate professional attributes (attitudes, behaviors, and identity) in their medical students." This qualitative study reports findings from open-ended survey questions from 123 medical students who observed a preceptor during house calls to elderly homebound patients. Their comments included reflections on the medical treatment as well as interactions with family and professional care providers. Student insights about the social learning process they experienced during house calls to geriatric patients characterized physician role models as dedicated, compassionate, and communicative. They also described patient care in the home environment as comprehensive, personalized, more relaxed, and comfortable. Student perceptions reflect an appreciation of the richness and complexity of details learned from home visits and social interaction with patients, families, and caregivers.

Profile modifications in laser-driven temperature fronts using flux-limiters and delocalization models

Science.gov (United States)

Colombant, Denis; Manheimer, Wallace; Busquet, Michel

2004-11-01

A simple steady-state model using flux-limiters by Day et al [1] showed that temperature profiles could formally be double-valued. Stability of temperature profiles in laser-driven temperature fronts using delocalization models was also discussed by Prasad and Kershaw [2]. We have observed steepening of the front and flattening of the maximum temperature in laser-driven implosions [3]. Following the simple model first proposed in [1], we solve for a two-boundary value steady-state heat flow problem for various non-local heat transport models. For the more complicated models [4,5], we obtain the steady-state solution as the asymptotic limit of the time-dependent solution. Solutions will be shown and compared for these various models. 1.M.Day, B.Merriman, F.Najmabadi and R.W.Conn, Contrib. Plasma Phys. 36, 419 (1996) 2.M.K.Prasad and D.S.Kershaw, Phys. Fluids B3, 3087 (1991) 3.D.Colombant, W.Manheimer and M.Busquet, Bull. Amer. Phys. Soc. 48, 326 (2003) 4.E.M.Epperlein and R.W.Short, Phys. Fluids B3, 3092 (1991) 5.W.Manheimer and D.Colombant, Phys. Plasmas 11, 260 (2004)

Applications of Bayesian temperature profile reconstruction to automated comparison with heat transport models and uncertainty quantification of current diffusion

International Nuclear Information System (INIS)

Irishkin, M.; Imbeaux, F.; Aniel, T.; Artaud, J.F.

2015-01-01

Highlights: • We developed a method for automated comparison of experimental data with models. • A unique platform implements Bayesian analysis and integrated modelling tools. • The method is tokamak-generic and is applied to Tore Supra and JET pulses. • Validation of a heat transport model is carried out. • We quantified the uncertainties due to Te profiles in current diffusion simulations. - Abstract: In the context of present and future long pulse tokamak experiments yielding a growing size of measured data per pulse, automating data consistency analysis and comparisons of measurements with models is a critical matter. To address these issues, the present work describes an expert system that carries out in an integrated and fully automated way (i) a reconstruction of plasma profiles from the measurements, using Bayesian analysis (ii) a prediction of the reconstructed quantities, according to some models and (iii) a comparison of the first two steps. The first application shown is devoted to the development of an automated comparison method between the experimental plasma profiles reconstructed using Bayesian methods and time dependent solutions of the transport equations. The method was applied to model validation of a simple heat transport model with three radial shape options. It has been tested on a database of 21 Tore Supra and 14 JET shots. The second application aims at quantifying uncertainties due to the electron temperature profile in current diffusion simulations. A systematic reconstruction of the Ne, Te, Ti profiles was first carried out for all time slices of the pulse. The Bayesian 95% highest probability intervals on the Te profile reconstruction were then used for (i) data consistency check of the flux consumption and (ii) defining a confidence interval for the current profile simulation. The method has been applied to one Tore Supra pulse and one JET pulse.

Enhancing the T-shaped learning profile when teaching hydrology using data, modeling, and visualization activities

Science.gov (United States)

Sanchez, Christopher A.; Ruddell, Benjamin L.; Schiesser, Roy; Merwade, Venkatesh

2016-03-01

Previous research has suggested that the use of more authentic learning activities can produce more robust and durable knowledge gains. This is consistent with calls within civil engineering education, specifically hydrology, that suggest that curricula should more often include professional perspective and data analysis skills to better develop the "T-shaped" knowledge profile of a professional hydrologist (i.e., professional breadth combined with technical depth). It was expected that the inclusion of a data-driven simulation lab exercise that was contextualized within a real-world situation and more consistent with the job duties of a professional in the field, would provide enhanced learning and appreciation of job duties beyond more conventional paper-and-pencil exercises in a lower-division undergraduate course. Results indicate that while students learned in both conditions, learning was enhanced for the data-driven simulation group in nearly every content area. This pattern of results suggests that the use of data-driven modeling and visualization activities can have a significant positive impact on instruction. This increase in learning likely facilitates the development of student perspective and conceptual mastery, enabling students to make better choices about their studies, while also better preparing them for work as a professional in the field.

The effect of call libraries and acoustic filters on the identification of bat echolocation

Science.gov (United States)

Clement, Matthew; Murray, Kevin L; Solick, Donald I; Gruver, Jeffrey C

2014-01-01

Quantitative methods for species identification are commonly used in acoustic surveys for animals. While various identification models have been studied extensively, there has been little study of methods for selecting calls prior to modeling or methods for validating results after modeling. We obtained two call libraries with a combined 1556 pulse sequences from 11 North American bat species. We used four acoustic filters to automatically select and quantify bat calls from the combined library. For each filter, we trained a species identification model (a quadratic discriminant function analysis) and compared the classification ability of the models. In a separate analysis, we trained a classification model using just one call library. We then compared a conventional model assessment that used the training library against an alternative approach that used the second library. We found that filters differed in the share of known pulse sequences that were selected (68 to 96%), the share of non-bat noises that were excluded (37 to 100%), their measurement of various pulse parameters, and their overall correct classification rate (41% to 85%). Although the top two filters did not differ significantly in overall correct classification rate (85% and 83%), rates differed significantly for some bat species. In our assessment of call libraries, overall correct classification rates were significantly lower (15% to 23% lower) when tested on the second call library instead of the training library. Well-designed filters obviated the need for subjective and time-consuming manual selection of pulses. Accordingly, researchers should carefully design and test filters and include adequate descriptions in publications. Our results also indicate that it may not be possible to extend inferences about model accuracy beyond the training library. If so, the accuracy of acoustic-only surveys may be lower than commonly reported, which could affect ecological understanding or management

Phase-I monitoring of standard deviations in multistage linear profiles

Science.gov (United States)

Kalaei, Mahdiyeh; Soleimani, Paria; Niaki, Seyed Taghi Akhavan; Atashgar, Karim

2018-03-01

In most modern manufacturing systems, products are often the output of some multistage processes. In these processes, the stages are dependent on each other, where the output quality of each stage depends also on the output quality of the previous stages. This property is called the cascade property. Although there are many studies in multistage process monitoring, there are fewer works on profile monitoring in multistage processes, especially on the variability monitoring of a multistage profile in Phase-I for which no research is found in the literature. In this paper, a new methodology is proposed to monitor the standard deviation involved in a simple linear profile designed in Phase I to monitor multistage processes with the cascade property. To this aim, an autoregressive correlation model between the stages is considered first. Then, the effect of the cascade property on the performances of three types of T 2 control charts in Phase I with shifts in standard deviation is investigated. As we show that this effect is significant, a U statistic is next used to remove the cascade effect, based on which the investigated control charts are modified. Simulation studies reveal good performances of the modified control charts.

Frogs Call at a Higher Pitch in Traffic Noise

Directory of Open Access Journals (Sweden)

Kirsten M. Parris

2009-06-01

Full Text Available Male frogs call to attract females for mating and to defend territories from rival males. Female frogs of some species prefer lower-pitched calls, which indicate larger, more experienced males. Acoustic interference occurs when background noise reduces the active distance or the distance over which an acoustic signal can be detected. Birds are known to call at a higher pitch or frequency in urban noise, decreasing acoustic interference from low-frequency noise. Using Bayesian linear regression, we investigated the effect of traffic noise on the pitch of advertisement calls in two species of frogs, the southern brown tree frog (Litoria ewingii and the common eastern froglet (Crinia signifera. We found evidence that L. ewingii calls at a higher pitch in traffic noise, with an average increase in dominant frequency of 4.1 Hz/dB of traffic noise, and a total effect size of 123 Hz. This frequency shift is smaller than that observed in birds, but is still large enough to be detected by conspecific frogs and confer a significant benefit to the caller. Mathematical modelling predicted a 24% increase in the active distance of a L. ewingii call in traffic noise with a frequency shift of this size. Crinia signifera may also call at a higher pitch in traffic noise, but more data are required to be confident of this effect. Because frog calls are innate rather than learned, the frequency shift demonstrated by L. ewingii may represent an evolutionary adaptation to noisy conditions. The phenomenon of frogs calling at a higher pitch in traffic noise could therefore constitute an intriguing trade-off between audibility and attractiveness to potential mates.

Spatiotemporal Analysis of Coronal Loops Using Seismology of Damped Kink Oscillations and Forward Modeling of EUV Intensity Profiles

Science.gov (United States)

Pascoe, D. J.; Anfinogentov, S. A.; Goddard, C. R.; Nakariakov, V. M.

2018-06-01

The shape of the damping profile of kink oscillations in coronal loops has recently allowed the transverse density profile of the loop to be estimated. This requires accurate measurement of the damping profile that can distinguish the Gaussian and exponential damping regimes, otherwise there are more unknowns than observables. Forward modeling of the transverse intensity profile may also be used to estimate the width of the inhomogeneous layer of a loop, providing an independent estimate of one of these unknowns. We analyze an oscillating loop for which the seismological determination of the transverse structure is inconclusive except when supplemented by additional spatial information from the transverse intensity profile. Our temporal analysis describes the motion of a coronal loop as a kink oscillation damped by resonant absorption, and our spatial analysis is based on forward modeling the transverse EUV intensity profile of the loop under the isothermal and optically thin approximations. We use Bayesian analysis and Markov chain Monte Carlo sampling to apply our spatial and temporal models both individually and simultaneously to our data and compare the results with numerical simulations. Combining the two methods allows both the inhomogeneous layer width and density contrast to be calculated, which is not possible for the same data when each method is applied individually. We demonstrate that the assumption of an exponential damping profile leads to a significantly larger error in the inferred density contrast ratio compared with a Gaussian damping profile.

Exact solutions to some nonlinear PDEs, travelling profiles method

Directory of Open Access Journals (Sweden)

Noureddine Benhamidouche

2008-04-01

\\end{equation*} by a new method that we call the travelling profiles method. This method allows us to find several forms of exact solutions including the classical forms such as travelling-wave and self-similar solutions.

Genome-Wide Expression Profiling of Five Mouse Models Identifies Similarities and Differences with Human Psoriasis

Science.gov (United States)

Swindell, William R.; Johnston, Andrew; Carbajal, Steve; Han, Gangwen; Wohn, Christian; Lu, Jun; Xing, Xianying; Nair, Rajan P.; Voorhees, John J.; Elder, James T.; Wang, Xiao-Jing; Sano, Shigetoshi; Prens, Errol P.; DiGiovanni, John; Pittelkow, Mark R.; Ward, Nicole L.; Gudjonsson, Johann E.

2011-01-01

Development of a suitable mouse model would facilitate the investigation of pathomechanisms underlying human psoriasis and would also assist in development of therapeutic treatments. However, while many psoriasis mouse models have been proposed, no single model recapitulates all features of the human disease, and standardized validation criteria for psoriasis mouse models have not been widely applied. In this study, whole-genome transcriptional profiling is used to compare gene expression patterns manifested by human psoriatic skin lesions with those that occur in five psoriasis mouse models (K5-Tie2, imiquimod, K14-AREG, K5-Stat3C and K5-TGFbeta1). While the cutaneous gene expression profiles associated with each mouse phenotype exhibited statistically significant similarity to the expression profile of psoriasis in humans, each model displayed distinctive sets of similarities and differences in comparison to human psoriasis. For all five models, correspondence to the human disease was strong with respect to genes involved in epidermal development and keratinization. Immune and inflammation-associated gene expression, in contrast, was more variable between models as compared to the human disease. These findings support the value of all five models as research tools, each with identifiable areas of convergence to and divergence from the human disease. Additionally, the approach used in this paper provides an objective and quantitative method for evaluation of proposed mouse models of psoriasis, which can be strategically applied in future studies to score strengths of mouse phenotypes relative to specific aspects of human psoriasis. PMID:21483750

Callings and Work Engagement: Moderated Mediation Model of Work Meaningfulness, Occupational Identity, and Occupational Self-Efficacy

Science.gov (United States)

Hirschi, Andreas

2012-01-01

Scholarly interest in callings is growing, but researchers' understanding of how and when callings relate to career outcomes is incomplete. The present study investigated the possibility that the relationship of calling to work engagement is mediated by work meaningfulness, occupational identity, and occupational self-efficacy--and that this…

Call Centre- Computer Telephone Integration

Directory of Open Access Journals (Sweden)

Dražen Kovačević

2012-10-01

Full Text Available Call centre largely came into being as a result of consumerneeds converging with enabling technology- and by the companiesrecognising the revenue opportunities generated by meetingthose needs thereby increasing customer satisfaction. Regardlessof the specific application or activity of a Call centre, customersatisfaction with the interaction is critical to the revenuegenerated or protected by the Call centre. Physical(v, Call centreset up is a place that includes computer, telephone and supervisorstation. Call centre can be available 24 hours a day - whenthe customer wants to make a purchase, needs information, orsimply wishes to register a complaint.

FLUX PROFILES AND MATHEMATICAL MODELING OF FOULING MECHANISM FOR ULTRAFILTRATION OF KONJAC GLUCOMANNAN

Directory of Open Access Journals (Sweden)

NITA ARYANTI

2016-07-01

Full Text Available This study was focused on principles and fouling analysis of konjac glucomannan (KGM separation using ultrafiltration system. Two Polyethersulfone membranes (PES having molecular weight cut-off of 10 and 20 kDa were used. It was found that membrane having larger pore size provided higher flux profiles. Evaluation of different transmembrane pressures resulted on possibility of more severe fouling at higher membrane pressure. With the increase of konjac glucomannan concentration, decrease of profile flux was observed. Further, a simple mathematical modelling of fouling mechanism was analyzed based on Hermia’s model. The images of membrane surfaces and cross-sections obtained by scanning electron microscopy (SEM were examined and being compared with the model. The research found that the fouling mechanisms of KGM ultrafiltration using membrane with pore size of 10 kDa was complete blocking. On the contrary, cake/gel layer formation was a fouling mechanism for ultrafiltration system with pore size of 20kDa.

Incorporating additional tree and environmental variables in a lodgepole pine stem profile model

Science.gov (United States)

John C. Byrne

1993-01-01

A new variable-form segmented stem profile model is developed for lodgepole pine (Pinus contorta) trees from the northern Rocky Mountains of the United States. I improved estimates of stem diameter by predicting two of the model coefficients with linear equations using a measure of tree form, defined as a ratio of dbh and total height. Additional improvements were...

Geothermal modeling along a two-dimensional crustal profile in Southern Portugal

Czech Academy of Sciences Publication Activity Database

Correia, A.; Šafanda, Jan

2002-01-01

Roč. 34, č. 1 (2002), s. 47-61 ISSN 0264-3707. [Geothermics at the turn of the century. Evora, 03.04.2000-07.04.2000] Institutional research plan: CEZ:AV0Z3012916 Keywords : geothermal modeling * Southern Portugal * surface heat flow * crustal profile Subject RIV: DC - Siesmology, Volcanology, Earth Structure Impact factor: 1.058, year: 2002

Titmouse calling and foraging are affected by head and body orientation of cat predator models and possible experience with real cats.

Science.gov (United States)

Book, D L; Freeberg, Todd M

2015-09-01

Although anti-predator behavior systems have been studied in diverse taxa, less is known about how prey species detect and assess the immediate threat posed by a predator based on its behavior. In this study, we evaluated a potential cue that some species may utilize when assessing predation threat-the predator's body and head orientation. We tested the effect of this orientation cue on signaling and predation-risk-sensitive foraging of a prey species, tufted titmice (Baeolophus bicolor). Earlier work revealed sensitivity of titmice and related species to the presence of predator stimuli. Here, we manipulated cat models to face either toward or away from a food source preferred by titmice and then measured titmouse calling and seed-taking behavior. Titmice showed greater feeder avoidance when the cat predator models faced the feeder, compared to when the models faced away from the feeder or when titmice were exposed to control stimuli. Titmouse calling was also sensitive to predator head/body orientation, depending upon whether titmice were from sites where real cats had been observed or not. This study experimentally demonstrated that both calling and foraging of prey species can be affected by the head and body orientation of an important terrestrial predator. Prey species may therefore signal in strategic ways to conspecifics not just about predator presence, but also urgency of threat related to the more subtle cue of the head and body orientation of the predator. These findings hold potential implications for understanding animal cognition and learning processes.

SNPMClust: Bivariate Gaussian Genotype Clustering and Calling for Illumina Microarrays

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Stephen W. Erickson

2016-07-01

Full Text Available SNPMClust is an R package for genotype clustering and calling with Illumina microarrays. It was originally developed for studies using the GoldenGate custom genotyping platform but can be used with other Illumina platforms, including Infinium BeadChip. The algorithm first rescales the fluorescent signal intensity data, adds empirically derived pseudo-data to minor allele genotype clusters, then uses the package mclust for bivariate Gaussian model fitting. We compared the accuracy and sensitivity of SNPMClust to that of GenCall, Illumina's proprietary algorithm, on a data set of 94 whole-genome amplified buccal (cheek swab DNA samples. These samples were genotyped on a custom panel which included 1064 SNPs for which the true genotype was known with high confidence. SNPMClust produced uniformly lower false call rates over a wide range of overall call rates.

Call cultures in orang-utans?

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Serge A Wich

Full Text Available BACKGROUND: Several studies suggested great ape cultures, arguing that human cumulative culture presumably evolved from such a foundation. These focused on conspicuous behaviours, and showed rich geographic variation, which could not be attributed to known ecological or genetic differences. Although geographic variation within call types (accents has previously been reported for orang-utans and other primate species, we examine geographic variation in the presence/absence of discrete call types (dialects. Because orang-utans have been shown to have geographic variation that is not completely explicable by genetic or ecological factors we hypothesized that this will be similar in the call domain and predict that discrete call type variation between populations will be found. METHODOLOGY/PRINCIPAL FINDINGS: We examined long-term behavioural data from five orang-utan populations and collected fecal samples for genetic analyses. We show that there is geographic variation in the presence of discrete types of calls. In exactly the same behavioural context (nest building and infant retrieval, individuals in different wild populations customarily emit either qualitatively different calls or calls in some but not in others. By comparing patterns in call-type and genetic similarity, we suggest that the observed variation is not likely to be explained by genetic or ecological differences. CONCLUSION/SIGNIFICANCE: These results are consistent with the potential presence of 'call cultures' and suggest that wild orang-utans possess the ability to invent arbitrary calls, which spread through social learning. These findings differ substantially from those that have been reported for primates before. First, the results reported here are on dialect and not on accent. Second, this study presents cases of production learning whereas most primate studies on vocal learning were cases of contextual learning. We conclude with speculating on how these findings might

Domain-oriented functional analysis based on expression profiling

Directory of Open Access Journals (Sweden)

Greene Jonathan

2002-10-01

Full Text Available Abstract Background Co-regulation of genes may imply involvement in similar biological processes or related function. Many clusters of co-regulated genes have been identified using microarray experiments. In this study, we examined co-regulated gene families using large-scale cDNA microarray experiments on the human transcriptome. Results We present a simple model, which, for each probe pair, distills expression changes into binary digits and summarizes the expression of multiple members of a gene family as the Family Regulation Ratio. The set of Family Regulation Ratios for each protein family across multiple experiments is called a Family Regulation Profile. We analyzed these Family Regulation Profiles using Pearson Correlation Coefficients and derived a network diagram portraying relationships between the Family Regulation Profiles of gene families that are well represented on the microarrays. Our strategy was cross-validated with two randomly chosen data subsets and was proven to be a reliable approach. Conclusion This work will help us to understand and identify the functional relationships between gene families and the regulatory pathways in which each family is involved. Concepts presented here may be useful for objective clustering of protein functions and deriving a comprehensive protein interaction map. Functional genomic approaches such as this may also be applicable to the elucidation of complex genetic regulatory networks.

Model-based Optimization and Feedback Control of the Current Density Profile Evolution in NSTX-U

Science.gov (United States)

Ilhan, Zeki Okan

Nuclear fusion research is a highly challenging, multidisciplinary field seeking contributions from both plasma physics and multiple engineering areas. As an application of plasma control engineering, this dissertation mainly explores methods to control the current density profile evolution within the National Spherical Torus eXperiment-Upgrade (NSTX-U), which is a substantial upgrade based on the NSTX device, which is located in Princeton Plasma Physics Laboratory (PPPL), Princeton, NJ. Active control of the toroidal current density profile is among those plasma control milestones that the NSTX-U program must achieve to realize its next-step operational goals, which are characterized by high-performance, long-pulse, MHD-stable plasma operation with neutral beam heating. Therefore, the aim of this work is to develop model-based, feedforward and feedback controllers that can enable time regulation of the current density profile in NSTX-U by actuating the total plasma current, electron density, and the powers of the individual neutral beam injectors. Motivated by the coupled, nonlinear, multivariable, distributed-parameter plasma dynamics, the first step towards control design is the development of a physics-based, control-oriented model for the current profile evolution in NSTX-U in response to non-inductive current drives and heating systems. Numerical simulations of the proposed control-oriented model show qualitative agreement with the high-fidelity physics code TRANSP. The next step is to utilize the proposed control-oriented model to design an open-loop actuator trajectory optimizer. Given a desired operating state, the optimizer produces the actuator trajectories that can steer the plasma to such state. The objective of the feedforward control design is to provide a more systematic approach to advanced scenario planning in NSTX-U since the development of such scenarios is conventionally carried out experimentally by modifying the tokamak's actuator

Sensitivity of a Chemical Mass Balance model for PM2.5 to source profiles for differing styles of cooking

Science.gov (United States)

Abdullahi, K. L.; Delgado-Saborit, J. M.; Harrison, Roy M.

2018-04-01

Use of a Chemical Mass Balance model is one of the two most commonly used approaches to estimating atmospheric concentrations of cooking aerosol. Such models require the input of chemical profiles for each of the main sources contributing to particulate matter mass and there is appreciable evidence from the literature that not only the mass emission but also the chemical composition of particulate matter varies according to the food being prepared and the style of cooking. In this study, aerosol has been sampled in the laboratory from four different styles of cooking, i.e. Indian, Chinese, Western and African cooking. The chemical profiles of molecular markers have been quantified and are used individually within a Chemical Mass Balance model applied to air samples collected in a multi-ethnic area of Birmingham, UK. The model results give a source contribution estimate for cooking aerosol which is consistent with other comparable UK studies, but also shows a very low sensitivity of the model to the cooking aerosol profile utilised. A survey of local restaurants suggested a wide range of cooking styles taking place which may explain why no one profile gives an appreciably better fit in the CMB model.

XACML profile and implementation for authorization interoperability between OSG and EGEE

International Nuclear Information System (INIS)

Garzoglio, G; Altunay, M; Chadwick, K; Hesselroth, T D; Levshina, T; Sfiligoi, I; Alderman, I; Miller, Z; Ananthakrishnan, R; Bester, J; Ciaschini, V; Ferraro, A; Forti, A; Demchenko, Y; Groep, D; Koeroo, O; Hover, J; Packard, J; Joie, C La; Sagehaug, H

2010-01-01

The Open Science Grid (OSG) and the Enabling Grids for E-sciencE (EGEE) have a common security model, based on Public Key Infrastructure. Grid resources grant access to users because of their membership in a Virtual Organization (VO), rather than on personal identity. Users push VO membership information to resources in the form of identity attributes, thus declaring that resources will be consumed on behalf of a specific group inside the organizational structure of the VO. Resources contact an access policies repository, centralized at each site, to grant the appropriate privileges for that VO group. Before the work in this paper, despite the commonality of the model, OSG and EGEE used different protocols for the communication between resources and the policy repositories. Hence, middleware developed for one Grid could not naturally be deployed on the other Grid, since the authorization module of the middleware would have to be enhanced to support the other Grid's communication protocol. In addition, maintenance and support for different authorization call-out protocols represents a duplication of effort for our relatively small community. To address these issues, OSG and EGEE initiated a joint project on authorization interoperability. The project defined a common communication protocol and attribute identity profile for authorization call-out and provided implementation and integration with major Grid middleware. The activity had resonance with middleware development communities, such as the Globus Toolkit and Condor, who decided to join the collaboration and contribute requirements and software. In this paper, we discuss the main elements of the profile, its implementation, and deployment in EGEE and OSG. We focus in particular on the operations of the authorization infrastructures of both Grids.

XACML profile and implementation for authorization interoperability between OSG and EGEE

Energy Technology Data Exchange (ETDEWEB)

Garzoglio, G.; Alderman, I.; Altunay, M.; Ananthakrishnan, R.; Bester, J.; Chadwick, K.; Ciaschini, V.; Demchenko, Y.; Ferraro, A.; Forti, A.; Groep, D.; /Fermilab /Wisconsin U., Madison /Argonne /INFN, CNAF /Amsterdam U. /NIKHEF, Amsterdam /Brookhaven /SWITCH, Zurich /Bergen Coll. Higher Educ.

2009-05-01

The Open Science Grid (OSG) and the Enabling Grids for E-sciencE (EGEE) have a common security model, based on Public Key Infrastructure. Grid resources grant access to users because of their membership in a Virtual Organization (VO), rather than on personal identity. Users push VO membership information to resources in the form of identity attributes, thus declaring that resources will be consumed on behalf of a specific group inside the organizational structure of the VO. Resources contact an access policies repository, centralized at each site, to grant the appropriate privileges for that VO group. Before the work in this paper, despite the commonality of the model, OSG and EGEE used different protocols for the communication between resources and the policy repositories. Hence, middleware developed for one Grid could not naturally be deployed on the other Grid, since the authorization module of the middleware would have to be enhanced to support the other Grid's communication protocol. In addition, maintenance and support for different authorization call-out protocols represents a duplication of effort for our relatively small community. To address these issues, OSG and EGEE initiated a joint project on authorization interoperability. The project defined a common communication protocol and attribute identity profile for authorization call-out and provided implementation and integration with major Grid middleware. The activity had resonance with middleware development communities, such as the Globus Toolkit and Condor, who decided to join the collaboration and contribute requirements and software. In this paper, we discuss the main elements of the profile, its implementation, and deployment in EGEE and OSG. We focus in particular on the operations of the authorization infrastructures of both Grids.

Theory and experiments on RF plasma heating, current drive and profile control in TORE SUPRA

International Nuclear Information System (INIS)

Moreau, D.

1994-01-01

This paper reviews the main experimental and theoretical achievements related to the study of RF heating and non-inductive current drive and particularly phenomena related to the current density profile control and the potentiality of producing stationary enhanced performance regimes: description of the Lower Hybrid (LH) and Ion Cyclotron Resonant Frequency (ICRF) systems; long pulse coupling performance of the RF systems; observation of the transition to the so-called ''stationary LHEP regime'' in which the (flat) central current density and (peaked) electron temperature profiles are fully decoupled; experiments on ICRF sawtooth stabilization with the combined effect of LHCD modifying the current density profile; diffusion of fast electrons generated by LH waves; ramp-up experiments in which the LH power provided a significant part of the resistive poloidal flux and flux consumption scaling; theory of spectral wave diffusion and multipass absorption; fast wave current drive modelling with the Alcyon full wave code; a reflector LH antenna concept. 18 figs., 48 refs

A veracity preserving model for synthesizing scalable electricity load profiles

OpenAIRE

Huang, Yunyou; Zhan, Jianfeng; Luo, Chunjie; Wang, Lei; Wang, Nana; Zheng, Daoyi; Fan, Fanda; Ren, Rui

2018-01-01

Electricity users are the major players of the electric systems, and electricity consumption is growing at an extraordinary rate. The research on electricity consumption behaviors is becoming increasingly important to design and deployment of the electric systems. Unfortunately, electricity load profiles are difficult to acquire. Data synthesis is one of the best approaches to solving the lack of data, and the key is the model that preserves the real electricity consumption behaviors. In this...

Adaptive LINE-P: An Adaptive Linear Energy Prediction Model for Wireless Sensor Network Nodes.

Science.gov (United States)

Ahmed, Faisal; Tamberg, Gert; Le Moullec, Yannick; Annus, Paul

2018-04-05

In the context of wireless sensor networks, energy prediction models are increasingly useful tools that can facilitate the power management of the wireless sensor network (WSN) nodes. However, most of the existing models suffer from the so-called fixed weighting parameter, which limits their applicability when it comes to, e.g., solar energy harvesters with varying characteristics. Thus, in this article we propose the Adaptive LINE-P (all cases) model that calculates adaptive weighting parameters based on the stored energy profiles. Furthermore, we also present a profile compression method to reduce the memory requirements. To determine the performance of our proposed model, we have used real data for the solar and wind energy profiles. The simulation results show that our model achieves 90-94% accuracy and that the compressed method reduces memory overheads by 50% as compared to state-of-the-art models.

Friedel's salt profiles from thermogravimetric analysis and thermodynamic modelling of Portland cement-based mortars exposed to sodium chloride solution

DEFF Research Database (Denmark)

Shi, Zhenguo; Geiker, Mette Rica; Lothenbach, Barbara

2017-01-01

Thermogravimetric analysis (TGA), powder X-ray diffraction (XRD) and thermodynamic modelling have been used to obtain Friedel's salt profiles for saturated mortar cylinders exposed to a 2.8 M NaCl solution. Comparison of the measured Friedel's salt profiles with the total chloride profiles...

The difficult medical emergency call

DEFF Research Database (Denmark)

Møller, Thea Palsgaard; Kjærulff, Thora Majlund; Viereck, Søren

2017-01-01

BACKGROUND: Pre-hospital emergency care requires proper categorization of emergency calls and assessment of emergency priority levels by the medical dispatchers. We investigated predictors for emergency call categorization as "unclear problem" in contrast to "symptom-specific" categories and the ......BACKGROUND: Pre-hospital emergency care requires proper categorization of emergency calls and assessment of emergency priority levels by the medical dispatchers. We investigated predictors for emergency call categorization as "unclear problem" in contrast to "symptom-specific" categories...... and the effect of categorization on mortality. METHODS: Register-based study in a 2-year period based on emergency call data from the emergency medical dispatch center in Copenhagen combined with nationwide register data. Logistic regression analysis (N = 78,040 individuals) was used for identification...

Effect of Bayesian Student Modeling on Academic Achievement in Foreign Language Teaching (University Level English Preparatory School Example)

Science.gov (United States)

Aslan, Burak Galip; Öztürk, Özlem; Inceoglu, Mustafa Murat

2014-01-01

Considering the increasing importance of adaptive approaches in CALL systems, this study implemented a machine learning based student modeling middleware with Bayesian networks. The profiling approach of the student modeling system is based on Felder and Silverman's Learning Styles Model and Felder and Soloman's Index of Learning Styles…

Automated comparison of Bayesian reconstructions of experimental profiles with physical models

International Nuclear Information System (INIS)

Irishkin, Maxim

2014-01-01

In this work we developed an expert system that carries out in an integrated and fully automated way i) a reconstruction of plasma profiles from the measurements, using Bayesian analysis ii) a prediction of the reconstructed quantities, according to some models and iii) an intelligent comparison of the first two steps. This system includes systematic checking of the internal consistency of the reconstructed quantities, enables automated model validation and, if a well-validated model is used, can be applied to help detecting interesting new physics in an experiment. The work shows three applications of this quite general system. The expert system can successfully detect failures in the automated plasma reconstruction and provide (on successful reconstruction cases) statistics of agreement of the models with the experimental data, i.e. information on the model validity. (author) [fr

Scaling laws for TEXT plasma profiles

International Nuclear Information System (INIS)

McCool, S.C.; Bravenec, R.V.; Chen, J.Y.; Foster, M.S.; Li, W.L.; Ouroura, A.; Phillips, P.E.; Richards, B.; Wenzel, K.W.; Zhang, Z.M.

1994-01-01

Regression analysis has been performed on a number of measured profiles including temperature and density vs. nominal macroscopic operating parameters for TEXT tokamak (pre-upgrade) ohmic plasmas. The resulting simple empirical model has enabled the authors to quickly approximate profiles of electron temperature and density, ion temperature, and soft x-ray brightness, as well as the scalar quantities: total radiated power, q=1 radius, sawtooth period and amplitude, and energy confinement time as a power law of toroidal field, plasma current, chord average density, and fueling gas atomic weight. The model profiles are only applicable to the plasma interior, i.e. within the limiter radius. In most cases the predicted model profiles are within the experimental error bars of measured profiles and are more accurate at predicting profile variation for small operating parameter changes than the measured profiles

Modeling and prediction of extraction profile for microwave-assisted extraction based on absorbed microwave energy.

Science.gov (United States)

Chan, Chung-Hung; Yusoff, Rozita; Ngoh, Gek-Cheng

2013-09-01

A modeling technique based on absorbed microwave energy was proposed to model microwave-assisted extraction (MAE) of antioxidant compounds from cocoa (Theobroma cacao L.) leaves. By adapting suitable extraction model at the basis of microwave energy absorbed during extraction, the model can be developed to predict extraction profile of MAE at various microwave irradiation power (100-600 W) and solvent loading (100-300 ml). Verification with experimental data confirmed that the prediction was accurate in capturing the extraction profile of MAE (R-square value greater than 0.87). Besides, the predicted yields from the model showed good agreement with the experimental results with less than 10% deviation observed. Furthermore, suitable extraction times to ensure high extraction yield at various MAE conditions can be estimated based on absorbed microwave energy. The estimation is feasible as more than 85% of active compounds can be extracted when compared with the conventional extraction technique. Copyright © 2013 Elsevier Ltd. All rights reserved.

78 FR 76218 - Rural Call Completion

Science.gov (United States)

2013-12-17

... calls to rural areas, and enforce restrictions against blocking, choking, reducing, or restricting calls... to alert the Commission of systemic problems receiving calls from a particular originating long... associated with completing calls to rural areas. These rules will also enhance our ability to enforce...

Long-distance calls in Neotropical primates

Directory of Open Access Journals (Sweden)

Oliveira Dilmar A.G.

2004-01-01

Full Text Available Long-distance calls are widespread among primates. Several studies concentrate on such calls in just one or in few species, while few studies have treated more general trends within the order. The common features that usually characterize these vocalizations are related to long-distance propagation of sounds. The proposed functions of primate long-distance calls can be divided into extragroup and intragroup ones. Extragroup functions relate to mate defense, mate attraction or resource defense, while intragroup functions involve group coordination or alarm. Among Neotropical primates, several species perform long-distance calls that seem more related to intragroup coordination, markedly in atelines. Callitrichids present long-distance calls that are employed both in intragroup coordination and intergroup contests or spacing. Examples of extragroup directed long-distance calls are the duets of titi monkeys and the roars and barks of howler monkeys. Considerable complexity and gradation exist in the long-distance call repertoires of some Neotropical primates, and female long-distance calls are probably more important in non-duetting species than usually thought. Future research must focus on larger trends in the evolution of primate long-distance calls, including the phylogeny of calling repertoires and the relationships between form and function in these signals.

Behavioral profiling as a translational approach in an animal model of posttraumatic stress disorder.

Science.gov (United States)

Ardi, Ziv; Albrecht, Anne; Richter-Levin, Alon; Saha, Rinki; Richter-Levin, Gal

2016-04-01

Diagnosis of psychiatric disorders in humans is based on comparing individuals to the normal population. However, many animal models analyze averaged group effects, thus compromising their translational power. This discrepancy is particularly relevant in posttraumatic stress disorder (PTSD), where only a minority develop the disorder following a traumatic experience. In our PTSD rat model, we utilize a novel behavioral profiling approach that allows the classification of affected and unaffected individuals in a trauma-exposed population. Rats were exposed to underwater trauma (UWT) and four weeks later their individual performances in the open field and elevated plus maze were compared to those of the control group, allowing the identification of affected and resilient UWT-exposed rats. Behavioral profiling revealed that only a subset of the UWT-exposed rats developed long-lasting behavioral symptoms. The proportion of affected rats was further enhanced by pre-exposure to juvenile stress, a well-described risk factor of PTSD. For a biochemical proof of concept we analyzed the expression levels of the GABAA receptor subunits α1 and α2 in the ventral, dorsal hippocampus and basolateral amygdala. Increased expression, mainly of α1, was observed in ventral but not dorsal hippocampus of exposed animals, which would traditionally be interpreted as being associated with the exposure-resultant psychopathology. However, behavioral profiling revealed that this increased expression was confined to exposed-unaffected individuals, suggesting a resilience-associated expression regulation. The results provide evidence for the importance of employing behavioral profiling in animal models of PTSD, in order to better understand the neural basis of stress vulnerability and resilience. Copyright © 2016 Elsevier Inc. All rights reserved.

Comparing mixing-length models of the diabatic wind profile over homogeneous terrain

DEFF Research Database (Denmark)

Pena Diaz, Alfredo; Gryning, Sven-Erik; Hasager, Charlotte Bay

2010-01-01

Models of the diabatic wind profile over homogeneous terrain for the entire atmospheric boundary layer are developed using mixing-length theory and are compared to wind speed observations up to 300 m at the National Test Station for Wind Turbines at Høvsøre, Denmark. The measurements are performe...

Short communication: relationship of call rate and accuracy of single nucleotide polymorphism genotypes in dairy cattle.

Science.gov (United States)

Cooper, T A; Wiggans, G R; VanRaden, P M

2013-05-01

Call rates on both a single nucleotide polymorphism (SNP) basis and an animal basis are used as measures of data quality and as screening tools for genomic studies and evaluations of dairy cattle. To investigate the relationship of SNP call rate and genotype accuracy for individual SNP, the correlation between percentages of missing genotypes and parent-progeny conflicts for each SNP was calculated for 103,313 Holsteins. Correlations ranged from 0.14 to 0.38 for the BovineSNP50 and BovineLD (Illumina Inc., San Diego, CA) and GeneSeek Genomic Profiler (Neogen Corp., Lincoln, NE) chips, with lower correlations for newer chips. For US genomic evaluations, genotypes are excluded for animals with a call rate of call rate for 220,175 Holstein, Jersey, and Brown Swiss genotypes was 99.6%. Animal genotypes with a call rate of ≤99% were examined from the US Department of Agriculture genotype database to determine how genotype call rate is related to accuracy of calls on an animal basis. Animal call rate was determined from SNP used in genomic evaluation and is the number of called autosomal and X-specific SNP genotypes divided by the number of SNP from that type of chip. To investigate the relationship of animal call rate and parentage validation, conflicts between a genotyped animal and its sire or dam were determined through a duo test (opposite homozygous SNP genotypes between sire and progeny; 1,374 animal genotypes) and a trio test (also including conflicts with dam and heterozygous SNP genotype for the animal when both parents are the same homozygote; 482 animal genotypes). When animal call rate was ≤ 80%, parentage validation was no longer reliable with the duo test. With the trio test, parentage validation was no longer reliable when animal call rate was ≤ 90%. To investigate how animal call rate was related to genotyping accuracy for animals with multiple genotypes, concordance between genotypes for 1,216 animals that had a genotype with a call rate of ≤ 99

HMM-ModE – Improved classification using profile hidden Markov models by optimising the discrimination threshold and modifying emission probabilities with negative training sequences

Directory of Open Access Journals (Sweden)

Nandi Soumyadeep

2007-03-01

Full Text Available Abstract Background Profile Hidden Markov Models (HMM are statistical representations of protein families derived from patterns of sequence conservation in multiple alignments and have been used in identifying remote homologues with considerable success. These conservation patterns arise from fold specific signals, shared across multiple families, and function specific signals unique to the families. The availability of sequences pre-classified according to their function permits the use of negative training sequences to improve the specificity of the HMM, both by optimizing the threshold cutoff and by modifying emission probabilities to minimize the influence of fold-specific signals. A protocol to generate family specific HMMs is described that first constructs a profile HMM from an alignment of the family's sequences and then uses this model to identify sequences belonging to other classes that score above the default threshold (false positives. Ten-fold cross validation is used to optimise the discrimination threshold score for the model. The advent of fast multiple alignment methods enables the use of the profile alignments to align the true and false positive sequences, and the resulting alignments are used to modify the emission probabilities in the original model. Results The protocol, called HMM-ModE, was validated on a set of sequences belonging to six sub-families of the AGC family of kinases. These sequences have an average sequence similarity of 63% among the group though each sub-group has a different substrate specificity. The optimisation of discrimination threshold, by using negative sequences scored against the model improves specificity in test cases from an average of 21% to 98%. Further discrimination by the HMM after modifying model probabilities using negative training sequences is provided in a few cases, the average specificity rising to 99%. Similar improvements were obtained with a sample of G-Protein coupled receptors

Variational Boussinesq model for simulation of coastal waves and tsunamis

NARCIS (Netherlands)

Adytia, D.; Adytia, Didit; van Groesen, Embrecht W.C.; Tan, Soon Keat; Huang, Zhenhua

2009-01-01

In this paper we describe the basic ideas of a so-called Variational Boussinesq Model which is based on the Hamiltonian structure of gravity surface waves. By using a rather simple approach to prescribe the profile of vertical fluid potential in the expression for the kinetic energy, we obtain a set

Occupational voice demands and their impact on the call-centre industry

Directory of Open Access Journals (Sweden)

Duffy OM

2009-04-01

Full Text Available Abstract Background Within the last decade there has been a growth in the call-centre industry in the UK, with a growing awareness of the voice as an important tool for successful communication. Occupational voice problems such as occupational dysphonia, in a business which relies on healthy, effective voice as the primary professional communication tool, may threaten working ability and occupational health and safety of workers. While previous studies of telephone call-agents have reported a range of voice symptoms and functional vocal health problems, there have been no studies investigating the use and impact of vocal performance in the communication industry within the UK. This study aims to address a significant gap in the evidence-base of occupational health and safety research. The objectives of the study are: 1. to investigate the work context and vocal communication demands for call-agents; 2. to evaluate call-agents' vocal health, awareness and performance; and 3. to identify key risks and training needs for employees and employers within call-centres. Methods and design This is an occupational epidemiological study, which plans to recruit call-centres throughout the UK and Ireland. Data collection will consist of three components: 1. interviews with managers from each participating call-centre to assess their communication and training needs; 2. an online biopsychosocial questionnaire will be administered to investigate the work environment and vocal demands of call-agents; and 3. voice acoustic measurements of a random sample of participants using the Multi-dimensional Voice Program (MDVP. Qualitative content analysis from the interviews will identify underlying themes and issues. A multivariate analysis approach will be adopted using Structural Equation Modelling (SEM, to develop voice measurement models in determining the construct validity of potential factors contributing to occupational dysphonia. Quantitative data will be

Seismic velocity model of the crust and upper mantle along profile PANCAKE across the Carpathians between the Pannonian Basin and the East European Craton

DEFF Research Database (Denmark)

Starostenko, V.; Janik, T.; Kolomiyets, K.

2013-01-01

the Transcarpathian Depression and the Carpathian Foredeep; and the south-western part of the EEC, including the Trans European Suture Zone (TESZ). Seismic data support a robust model of the Vp velocity structure of the crust. In the PB, the 22-23km thick crust consists of a 2-5km thick sedimentary layer (Vp=2......Results are presented of a seismic wide-angle reflection/refraction survey along a profile between the Pannonian Basin (PB) and the East European Craton (EEC) called PANCAKE. The P- and S-wave velocity model derived can be divided into three sectors: the PB; the Carpathians, including.......4-3.7km/s), 17-20km thick upper crystalline crust (5.9-6.3km/s) and an up to 3km thick lower crustal layer (Vp=6.4km/s). In the central part of the Carpathians, a 10-24km thick uppermost part of the crust with Vp≤6.0km/s may correspond to sedimentary rocks of different ages; several high velocity bodies...

Sleep Quality of Call Handlers Employed in International Call Centers in National Capital Region of Delhi, India.

Science.gov (United States)

Raja, J D; Bhasin, S K

2016-10-01

Call center sector in India is a relatively new and fast growing industry driving employment and growth in modern India today. Most international call centers in National Capital Region (NCR) of Delhi operate at odd work hours corresponding to a time suitable fortheir international customers. The sleep quality of call handlers employed in these call centers is in jeopardy owing to their altered sleep schedule. To assess the sleep quality and determine its independent predictors among call handlers employed in international call centers in NCR of Delhi. A cross-sectional questionnaire-based study was conducted on 375 call handlers aged 18-39 years employed in international call centers in NCR of Delhi. Sleep quality was assessed using Athens Insomnia scale along with a pre-tested, structured questionnaire. The mean age of respondents was 24.6 (SD 2.4) years. 78% of participants were male. 83.5% of respondents were unmarried. 44.3% of call handlers were cigarette smokers. Physical ailments were reported by 37% call handlers. 77.6% of call handlers had somesuspicion of insomnia or suspected insomnia; the rest had no sleep problem. Smoking, poor social support, heavy workload, lack of relaxation facility at office, and prolonged travel time to office were independent predictors of sleep quality (pSafeguarding their health becomes an occupational health challenge to public health specialists.

A model for quantification of temperature profiles via germination times

DEFF Research Database (Denmark)

Pipper, Christian Bressen; Adolf, Verena Isabelle; Jacobsen, Sven-Erik

2013-01-01

Current methodology to quantify temperature characteristics in germination of seeds is predominantly based on analysis of the time to reach a given germination fraction, that is, the quantiles in the distribution of the germination time of a seed. In practice interpolation between observed...... time and a specific type of accelerated failure time models is provided. As a consequence the observed number of germinated seeds at given monitoring times may be analysed directly by a grouped time-to-event model from which characteristics of the temperature profile may be identified and estimated...... germination fractions at given monitoring times is used to obtain the time to reach a given germination fraction. As a consequence the obtained value will be highly dependent on the actual monitoring scheme used in the experiment. In this paper a link between currently used quantile models for the germination...

Callings and Organizational Behavior

Science.gov (United States)

Elangovan, A. R.; Pinder, Craig C.; McLean, Murdith

2010-01-01

Current literature on careers, social identity and meaning in work tends to understate the multiplicity, historical significance, and nuances of the concept of calling(s). In this article, we trace the evolution of the concept from its religious roots into secular realms and develop a typology of interpretations using occupation and religious…

Uncertain call likelihood negatively affects sleep and next-day cognitive performance while on-call in a laboratory environment.

Science.gov (United States)

Sprajcer, Madeline; Jay, Sarah M; Vincent, Grace E; Vakulin, Andrew; Lack, Leon; Ferguson, Sally A

2018-05-11

On-call working arrangements are employed in a number of industries to manage unpredictable events, and often involve tasks that are safety- or time-critical. This study investigated the effects of call likelihood during an overnight on-call shift on self-reported pre-bed anxiety, sleep and next-day cognitive performance. A four-night laboratory-based protocol was employed, with an adaptation, a control and two counterbalanced on-call nights. On one on-call night, participants were instructed that they would definitely be called during the night, while on the other on-call night they were told they may be called. The State-Trait Anxiety Inventory form x-1 was used to investigate pre-bed anxiety, and sleep was assessed using polysomnography and power spectral analysis of the sleep electroencephalographic analysis. Cognitive performance was assessed four times daily using a 10-min psychomotor vigilance task. Participants felt more anxious before bed when they were definitely going to be called, compared with the control and maybe conditions. Conversely, participants experienced significantly less non-rapid eye movement and stage two sleep and poorer cognitive performance when told they may be called. Further, participants had significantly more rapid eye movement sleep in the maybe condition, which may be an adaptive response to the stress associated with this on-call condition. It appears that self-reported anxiety may not be linked with sleep outcomes while on-call. However, this research indicates that it is important to take call likelihood into consideration when constructing rosters and risk-management systems for on-call workers.

Developing a forecast model of solar proton flux profiles for well-connected events

Science.gov (United States)

Ji, E. Y.; Moon, Y. J.; Park, J.

2014-12-01

We have developed a forecast model of solar proton flux profile (> 10 MeV channel) for well-connected events. Among 136 solar proton events (SPEs) from 1986 to 2006, we select 49 well-connected ones that are all associated with single X-ray flares stronger than M1 class and start to increase within four hours after their X-ray peak times. These events show rapid increments in proton flux. By comparing several empirical functions, we select a modified Weibull curve function to approximate a SPE flux profile, which is similar to the particle injection rate. The parameters (peak value, rise time and decay time) of this function are determined by the relationship between X-ray flare parameters (peak flux, impulsive time, and emission measure) and SPE parameters. For 49 well-connected SPEs, the linear correlation between the predicted proton peak flux and the observed proton peak fluxes is 0.65 with the RMS error of 0.55 pfu in the log10. In addition, we have developed another forecast model based on flare and CME parameters using 22 SPEs. The used CME parameters are linear speed and angular width. As a result, we find that the linear correlation between the predicted proton peak flux and the observed proton peak fluxes is 0.83 with the RMS error of 0.35 pfu in the log10. From the relationship between the model error and CME acceleration, we find that CME acceleration is also an important factor for predicting proton flux profiles.

Cognitive branding and the value profile

DEFF Research Database (Denmark)

Thellefsen, Torkild Leo; Sørensen, Bent; Danesi, Marcel

2013-01-01

The aim of this paper is to present a pragmatic inspired branding method called a value profile, within the theory of cognitive branding. The method is theoretical anchored in Charles S. Peirce's pragmatic theory and can be used to identify the core values of brands and also identify the possible...... consequences of how these values influence people to purchase products. Moreover, it can be used to analyze the values themselves...

Erlang C Formula and its Use in the Call Centers

Directory of Open Access Journals (Sweden)

Erik Chromy

2011-01-01

Full Text Available This paper deals with calculation of important parameters of the Call Center using the Erlang C formula and then results are verified through simulations. Erlang C formula is defined as a function of two variables: the number of agents N and the load A. On the base of their values it is possible to determine the probability PC, that the incoming call will not be served immediately, but it will have to wait in the waiting queue. Simulations satisfy the assumption of Markov models.

The so-called "Spanish model" - Tobacco industry strategies and its impact in Europe and Latin America

Directory of Open Access Journals (Sweden)

Schneider Nick K

2011-12-01

Full Text Available Abstract Background To demonstrate the tobacco industry rationale behind the "Spanish model" on non-smokers' protection in hospitality venues and the impact it had on some European and Latin American countries between 2006 and 2011. Methods Tobacco industry documents research triangulated against news and media reports. Results As an alternative to the successful implementation of 100% smoke-free policies, several European and Latin American countries introduced partial smoking bans based on the so-called "Spanish model", a legal framework widely advocated by parts of the hospitality industry with striking similarities to "accommodation programmes" promoted by the tobacco industry in the late 1990s. These developments started with the implementation of the Spanish tobacco control law (Ley 28/2005 in 2006 and have increased since then. Conclusion The Spanish experience demonstrates that partial smoking bans often resemble tobacco industry strategies and are used to spread a failed approach on international level. Researchers, advocates and policy makers should be aware of this ineffective policy.

The so-called "Spanish model" - Tobacco industry strategies and its impact in Europe and Latin America

Science.gov (United States)

2011-01-01

Background To demonstrate the tobacco industry rationale behind the "Spanish model" on non-smokers' protection in hospitality venues and the impact it had on some European and Latin American countries between 2006 and 2011. Methods Tobacco industry documents research triangulated against news and media reports. Results As an alternative to the successful implementation of 100% smoke-free policies, several European and Latin American countries introduced partial smoking bans based on the so-called "Spanish model", a legal framework widely advocated by parts of the hospitality industry with striking similarities to "accommodation programmes" promoted by the tobacco industry in the late 1990s. These developments started with the implementation of the Spanish tobacco control law (Ley 28/2005) in 2006 and have increased since then. Conclusion The Spanish experience demonstrates that partial smoking bans often resemble tobacco industry strategies and are used to spread a failed approach on international level. Researchers, advocates and policy makers should be aware of this ineffective policy. PMID:22151884

Modelling of JET diagnostics using Bayesian Graphical Models

Energy Technology Data Exchange (ETDEWEB)

Svensson, J. [IPP Greifswald, Greifswald (Germany); Ford, O. [Imperial College, London (United Kingdom); McDonald, D.; Hole, M.; Nessi, G. von; Meakins, A.; Brix, M.; Thomsen, H.; Werner, A.; Sirinelli, A.

2011-07-01

The mapping between physics parameters (such as densities, currents, flows, temperatures etc) defining the plasma 'state' under a given model and the raw observations of each plasma diagnostic will 1) depend on the particular physics model used, 2) is inherently probabilistic, from uncertainties on both observations and instrumental aspects of the mapping, such as calibrations, instrument functions etc. A flexible and principled way of modelling such interconnected probabilistic systems is through so called Bayesian graphical models. Being an amalgam between graph theory and probability theory, Bayesian graphical models can simulate the complex interconnections between physics models and diagnostic observations from multiple heterogeneous diagnostic systems, making it relatively easy to optimally combine the observations from multiple diagnostics for joint inference on parameters of the underlying physics model, which in itself can be represented as part of the graph. At JET about 10 diagnostic systems have to date been modelled in this way, and has lead to a number of new results, including: the reconstruction of the flux surface topology and q-profiles without any specific equilibrium assumption, using information from a number of different diagnostic systems; profile inversions taking into account the uncertainties in the flux surface positions and a substantial increase in accuracy of JET electron density and temperature profiles, including improved pedestal resolution, through the joint analysis of three diagnostic systems. It is believed that the Bayesian graph approach could potentially be utilised for very large sets of diagnostics, providing a generic data analysis framework for nuclear fusion experiments, that would be able to optimally utilize the information from multiple diagnostics simultaneously, and where the explicit graph representation of the connections to underlying physics models could be used for sophisticated model testing. This

Acceptance factors for the use of video call via smartphone by blind people

OpenAIRE

Tamanit Chanjaraspong

2017-01-01

Using video call via smartphones is a new technology for blind people which can be applied to facilitate their daily lives. This video call technology is different from old technology and the technology acceptance has changed users' behavior in society, culture, and especially attitude toward using new technology. This research studied the intention and the need to use video call via smartphone by blind people according to the Technology Acceptance Model, a famous and widely-accepted theory f...

Final Technical Report: Numerical and Experimental Investigation of Turbulent Transport Control via Shaping of Radial Plasma Flow Profiles

Energy Technology Data Exchange (ETDEWEB)

Schuster, Eugenio

2014-05-02

The strong coupling between the different physical variables involved in the plasma transport phenomenon and the high complexity of its dynamics call for a model-based, multivariable approach to profile control where those predictive models could be exploited. The overall objective of this project has been to extend the existing body of work by investigating numerically and experimentally active control of unstable fluctuations, including fully developed turbulence and the associated cross-field particle transport, via manipulation of flow profiles in a magnetized laboratory plasma device. Fluctuations and particle transport can be monitored by an array of electrostatic probes, and Ex B flow profiles can be controlled via a set of biased concentric ring electrodes that terminate the plasma column. The goals of the proposed research have been threefold: i- to develop a predictive code to simulate plasma transport in the linear HELCAT (HELicon-CAThode) plasma device at the University of New Mexico (UNM), where the experimental component of the proposed research has been carried out; ii- to establish the feasibility of using advanced model-based control algorithms to control cross-field turbulence-driven particle transport through appropriate manipulation of radial plasma flow profiles, iii- to investigate the fundamental nonlinear dynamics of turbulence and transport physics. Lehigh University (LU), including Prof. Eugenio Schuster and one full-time graduate student, has been primarily responsible for control-oriented modeling and model-based control design. Undergraduate students have also participated in this project through the National Science Foundation Research Experience for Undergraduate (REU) program. The main goal of the LU Plasma Control Group has been to study the feasibility of controlling turbulence-driven transport by shaping the radial poloidal flow profile (i.e., by controlling flow shear) via biased concentric ring electrodes.

High call volume at poison control centers: identification and implications for communication.

Science.gov (United States)

Caravati, E M; Latimer, S; Reblin, M; Bennett, H K W; Cummins, M R; Crouch, B I; Ellington, L

2012-09-01

High volume surges in health care are uncommon and unpredictable events. Their impact on health system performance and capacity is difficult to study. To identify time periods that exhibited very busy conditions at a poison control center and to determine whether cases and communication during high volume call periods are different from cases during low volume periods. Call data from a US poison control center over twelve consecutive months was collected via a call logger and an electronic case database (Toxicall®).Variables evaluated for high call volume conditions were: (1) call duration; (2) number of cases; and (3) number of calls per staff member per 30 minute period. Statistical analyses identified peak periods as busier than 99% of all other 30 minute time periods and low volume periods as slower than 70% of all other 30 minute periods. Case and communication characteristics of high volume and low volume calls were compared using logistic regression. A total of 65,364 incoming calls occurred over 12 months. One hundred high call volume and 4885 low call volume 30 minute periods were identified. High volume periods were more common between 1500 and 2300 hours and during the winter months. Coded verbal communication data were evaluated for 42 high volume and 296 low volume calls. The mean (standard deviation) call length of these calls during high volume and low volume periods was 3 minutes 27 seconds (1 minute 46 seconds) and 3 minutes 57 seconds (2 minutes 11 seconds), respectively. Regression analyses revealed a trend for fewer overall verbal statements and fewer staff questions during peak periods, but no other significant differences for staff-caller communication behaviors were found. Peak activity for poison center call volume can be identified by statistical modeling. Calls during high volume periods were similar to low volume calls. Communication was more concise yet staff was able to maintain a good rapport with callers during busy call periods

Care and calls

DEFF Research Database (Denmark)

Paasch, Bettina Sletten

-centred care through the use of tactile resources and embodied orientations while they attend to the phone call. Experienced nurses Thus perform multiactivity by distributing attention towards both the patient and the phone, and the analysis shows that their concrete ways of doing so depend on the complex...... they are telephoned during interactions with patients are not universal. Indeed different strategies have evolved in other hospital departments. Not only does this thesis contribute insights into the way nurses manage phone calls during interactions with patients, but by subscribing to a growing body of embodied...... of human interaction....

Trayvon Martin: Racial Profiling, Black Male Stigma, and Social Work Practice.

Science.gov (United States)

Teasley, Martell Lee; Schiele, Jerome H; Adams, Charles; Okilwa, Nathern S

2018-01-01

To address a critical gap in the social work literature, this article examines the deleterious effects of racial profiling as it pertains to police targeting of male African Americans. The authors use the Trayvon Martin court case to exemplify how racial profiling and black male stigma help perpetuate social inequality and injustice for black men. A racism-centered perspective is examined historically and contemporarily as a theoretical approach to understanding the role that race plays in social injustice through racial profiling. Implications for social work research design and practice aimed at increasing the social work knowledge base on racial profiling are discussed. The authors call for attention and advocacy by major social work organizations in the reduction of black male stigma and racial profiling. © 2017 National Association of Social Workers.

From the SAIN,LIM system to the SENS algorithm: a review of a French approach of nutrient profiling.

Science.gov (United States)

Tharrey, Marion; Maillot, Matthieu; Azaïs-Braesco, Véronique; Darmon, Nicole

2017-08-01

Nutrient profiling aims to classify or rank foods according to their nutritional composition to assist policies aimed at improving the nutritional quality of foods and diets. The present paper reviews a French approach of nutrient profiling by describing the SAIN,LIM system and its evolution from its early draft to the simplified nutrition labelling system (SENS) algorithm. Considered in 2010 by WHO as the 'French model' of nutrient profiling, SAIN,LIM classifies foods into four classes based on two scores: a nutrient density score (NDS) called SAIN and a score of nutrients to limit called LIM, and one threshold on each score. The system was first developed by the French Food Standard Agency in 2008 in response to the European regulation on nutrition and health claims (European Commission (EC) 1924/2006) to determine foods that may be eligible for bearing claims. Recently, the European regulation (EC 1169/2011) on the provision of food information to consumers allowed simplified nutrition labelling to facilitate consumer information and help them make fully informed choices. In that context, the SAIN,LIM was adapted to obtain the SENS algorithm, a system able to rank foods for simplified nutrition labelling. The implementation of the algorithm followed a step-by-step, systematic, transparent and logical process where shortcomings of the SAIN,LIM were addressed by integrating specificities of food categories in the SENS, reducing the number of nutrients, ordering the four classes and introducing European reference intakes. Through the French example, this review shows how an existing nutrient profiling system can be specifically adapted to support public health nutrition policies.

A comparative analysis of the statistical properties of large mobile phone calling networks.

Science.gov (United States)

Li, Ming-Xia; Jiang, Zhi-Qiang; Xie, Wen-Jie; Miccichè, Salvatore; Tumminello, Michele; Zhou, Wei-Xing; Mantegna, Rosario N

2014-05-30

Mobile phone calling is one of the most widely used communication methods in modern society. The records of calls among mobile phone users provide us a valuable proxy for the understanding of human communication patterns embedded in social networks. Mobile phone users call each other forming a directed calling network. If only reciprocal calls are considered, we obtain an undirected mutual calling network. The preferential communication behavior between two connected users can be statistically tested and it results in two Bonferroni networks with statistically validated edges. We perform a comparative analysis of the statistical properties of these four networks, which are constructed from the calling records of more than nine million individuals in Shanghai over a period of 110 days. We find that these networks share many common structural properties and also exhibit idiosyncratic features when compared with previously studied large mobile calling networks. The empirical findings provide us an intriguing picture of a representative large social network that might shed new lights on the modelling of large social networks.

Lipid profiling of in vitro cell models of adipogenic differentiation: relationships with mouse adipose tissues

OpenAIRE

Liaw, Lucy; Prudovsky, Igor; Koza, Robert A.; Anunciado-Koza, Rea V.; Siviski, Matthew E.; Lindner, Volkhard; Friesel, Robert E.; Rosen, Clifford J.; Baker, Paul R.S.; Simons, Brigitte; Vary, Calvin P.H.

2016-01-01

Our objective was to characterize lipid profiles in cell models of adipocyte differentiation in comparison to mouse adipose tissues in vivo. A novel lipid extraction strategy was combined with global lipid profiling using direct infusion and sequential precursor ion fragmentation, termed MS/MSALL. Perirenal and inguinal white adipose tissue and interscapular brown adipose tissues from adult C57BL/6J mice were analyzed. 3T3-L1 preadipocytes, ear mesenchymal progenitor cells, and brown adipose-...

New geometric design consistency model based on operating speed profiles for road safety evaluation.

Science.gov (United States)

Camacho-Torregrosa, Francisco J; Pérez-Zuriaga, Ana M; Campoy-Ungría, J Manuel; García-García, Alfredo

2013-12-01

To assist in the on-going effort to reduce road fatalities as much as possible, this paper presents a new methodology to evaluate road safety in both the design and redesign stages of two-lane rural highways. This methodology is based on the analysis of road geometric design consistency, a value which will be a surrogate measure of the safety level of the two-lane rural road segment. The consistency model presented in this paper is based on the consideration of continuous operating speed profiles. The models used for their construction were obtained by using an innovative GPS-data collection method that is based on continuous operating speed profiles recorded from individual drivers. This new methodology allowed the researchers to observe the actual behavior of drivers and to develop more accurate operating speed models than was previously possible with spot-speed data collection, thereby enabling a more accurate approximation to the real phenomenon and thus a better consistency measurement. Operating speed profiles were built for 33 Spanish two-lane rural road segments, and several consistency measurements based on the global and local operating speed were checked. The final consistency model takes into account not only the global dispersion of the operating speed, but also some indexes that consider both local speed decelerations and speeds over posted speeds as well. For the development of the consistency model, the crash frequency for each study site was considered, which allowed estimating the number of crashes on a road segment by means of the calculation of its geometric design consistency. Consequently, the presented consistency evaluation method is a promising innovative tool that can be used as a surrogate measure to estimate the safety of a road segment. Copyright © 2012 Elsevier Ltd. All rights reserved.

Gravity and magnetic modelling in the Vrancea Zone, south-eastern Carpathians: Redefinition of the edge of the East European Craton beneath the south-eastern Carpathians

NARCIS (Netherlands)

Bocin, A.; Stephenson, R.; Matenco, L.; Mocanu, V.

2013-01-01

A 2D gravity and magnetic data model has been constructed along a 71. km densely observed profile, called DACIA PLAN GRAV MAN's. The profile crosses part of the nappe pile of the south-eastern Carpathians and includes the seismically active Vrancea Zone and was acquired with the objective to

Neural Network-Based Model for Landslide Susceptibility and Soil Longitudinal Profile Analyses

DEFF Research Database (Denmark)

Farrokhzad, F.; Barari, Amin; Choobbasti, A. J.

2011-01-01

The purpose of this study was to create an empirical model for assessing the landslide risk potential at Savadkouh Azad University, which is located in the rural surroundings of Savadkouh, about 5 km from the city of Pol-Sefid in northern Iran. The soil longitudinal profile of the city of Babol......, located 25 km from the Caspian Sea, also was predicted with an artificial neural network (ANN). A multilayer perceptron neural network model was applied to the landslide area and was used to analyze specific elements in the study area that contributed to previous landsliding events. The ANN models were...... studies in landslide susceptibility zonation....

Calls to Florida Poison Control Centers about mercury: Trends over 2003-2013.

Science.gov (United States)

Gribble, Matthew O; Deshpande, Aniruddha; Stephan, Wendy B; Hunter, Candis M; Weisman, Richard S

2017-11-01

The aim of this analysis was to contrast trends in exposure-report calls and informational queries (a measure of public interest) about mercury to the Florida Poison Control Centers over 2003-2013. Poison-control specialists coded calls to Florida Poison Control Centers by substance of concern, caller demographics, and whether the call pertained to an exposure event or was an informational query. For the present study, call records regarding mercury were de-identified and provided along with daily total number of calls for statistical analysis. We fit Poisson models using generalized estimating equations to summarize changes across years in counts of daily calls to Florida Poison Control Centers, adjusting for month. In a second stage of analysis, we further adjusted for the total number of calls each day. We also conducted analyses stratified by age of the exposed. There was an overall decrease over 2003-2013 in the number of total calls about mercury [Ratio per year: 0.89, 95% CI: (0.88, 0.90)], and calls about mercury exposure [Ratio per year: 0.84, 95% CI: (0.83, 0.85)], but the number of informational queries about mercury increased over this time [Ratio per year: 1.15 (95% CI: 1.12, 1.18)]. After adjusting for the number of calls of that type each day (e.g., call volume), the associations remained similar: a ratio of 0.88 (95% CI: 0.87, 0.89) per year for total calls, 0.85 (0.83, 0.86) for exposure-related calls, and 1.17 (1.14, 1.21) for informational queries. Although, the number of exposure-related calls decreased, informational queries increased over 2003-2013. This might suggest an increased public interest in mercury health risks despite a decrease in reported exposures over this time period. Copyright © 2017 Elsevier Inc. All rights reserved.

Profile-likelihood Confidence Intervals in Item Response Theory Models.

Science.gov (United States)

Chalmers, R Philip; Pek, Jolynn; Liu, Yang

2017-01-01

Confidence intervals (CIs) are fundamental inferential devices which quantify the sampling variability of parameter estimates. In item response theory, CIs have been primarily obtained from large-sample Wald-type approaches based on standard error estimates, derived from the observed or expected information matrix, after parameters have been estimated via maximum likelihood. An alternative approach to constructing CIs is to quantify sampling variability directly from the likelihood function with a technique known as profile-likelihood confidence intervals (PL CIs). In this article, we introduce PL CIs for item response theory models, compare PL CIs to classical large-sample Wald-type CIs, and demonstrate important distinctions among these CIs. CIs are then constructed for parameters directly estimated in the specified model and for transformed parameters which are often obtained post-estimation. Monte Carlo simulation results suggest that PL CIs perform consistently better than Wald-type CIs for both non-transformed and transformed parameters.

ADPROCLUS: a graphical user interface for fitting additive profile clustering models to object by variable data matrices.

Science.gov (United States)

Wilderjans, Tom F; Ceulemans, Eva; Van Mechelen, Iven; Depril, Dirk

2011-03-01

In many areas of psychology, one is interested in disclosing the underlying structural mechanisms that generated an object by variable data set. Often, based on theoretical or empirical arguments, it may be expected that these underlying mechanisms imply that the objects are grouped into clusters that are allowed to overlap (i.e., an object may belong to more than one cluster). In such cases, analyzing the data with Mirkin's additive profile clustering model may be appropriate. In this model: (1) each object may belong to no, one or several clusters, (2) there is a specific variable profile associated with each cluster, and (3) the scores of the objects on the variables can be reconstructed by adding the cluster-specific variable profiles of the clusters the object in question belongs to. Until now, however, no software program has been publicly available to perform an additive profile clustering analysis. For this purpose, in this article, the ADPROCLUS program, steered by a graphical user interface, is presented. We further illustrate its use by means of the analysis of a patient by symptom data matrix.

Effect of practical training on the learning motivation profile of Japanese pharmacy students using structural equation modeling.

Science.gov (United States)

Yamamura, Shigeo; Takehira, Rieko

2017-01-01

To establish a model of Japanese pharmacy students' learning motivation profile and investigate the effects of pharmaceutical practical training programs on their learning motivation. The Science Motivation Questionnaire II was administered to pharmacy students in their 4th (before practical training), 5th (before practical training at clinical sites), and 6th (after all practical training) years of study at Josai International University in April, 2016. Factor analysis and multiple-group structural equation modeling were conducted for data analysis. A total of 165 students participated. The learning motivation profile was modeled with 4 factors (intrinsic, career, self-determination, and grade motivation), and the most effective learning motivation was grade motivation. In the multiple-group analysis, the fit of the model with the data was acceptable, and the estimated mean value of the factor of 'self-determination' in the learning motivation profile increased after the practical training programs (P= 0.048, Cohen's d = 0.43). Practical training programs in a 6-year course were effective for increasing learning motivation, based on 'self-determination' among Japanese pharmacy students. The results suggest that practical training programs are meaningful not only for providing clinical experience but also for raising learning motivation.

A semiparametric modeling framework for potential biomarker discovery and the development of metabonomic profiles

Directory of Open Access Journals (Sweden)

Dey Dipak K

2008-01-01

Full Text Available Abstract Background The discovery of biomarkers is an important step towards the development of criteria for early diagnosis of disease status. Recently electrospray ionization (ESI and matrix assisted laser desorption (MALDI time-of-flight (TOF mass spectrometry have been used to identify biomarkers both in proteomics and metabonomics studies. Data sets generated from such studies are generally very large in size and thus require the use of sophisticated statistical techniques to glean useful information. Most recent attempts to process these types of data model each compound's intensity either discretely by positional (mass to charge ratio clustering or through each compounds' own intensity distribution. Traditionally data processing steps such as noise removal, background elimination and m/z alignment, are generally carried out separately resulting in unsatisfactory propagation of signals in the final model. Results In the present study a novel semi-parametric approach has been developed to distinguish urinary metabolic profiles in a group of traumatic patients from those of a control group consisting of normal individuals. Data sets obtained from the replicates of a single subject were used to develop a functional profile through Dirichlet mixture of beta distribution. This functional profile is flexible enough to accommodate variability of the instrument and the inherent variability of each individual, thus simultaneously addressing different sources of systematic error. To address instrument variability, all data sets were analyzed in replicate, an important issue ignored by most studies in the past. Different model comparisons were performed to select the best model for each subject. The m/z values in the window of the irregular pattern are then further recommended for possible biomarker discovery. Conclusion To the best of our knowledge this is the very first attempt to model the physical process behind the time-of flight mass

Social Learning: Medical Student Perceptions of Geriatric House Calls

Science.gov (United States)

Abbey, Linda; Willett, Rita; Selby-Penczak, Rachel; McKnight, Roberta

2010-01-01

Bandura's social learning theory provides a useful conceptual framework to understand medical students' perceptions of a house calls experience at Virginia Commonwealth University School of Medicine. Social learning and role modeling reflect Liaison Committee on Medical Education guidelines for "Medical schools (to) ensure that the learning…

Profile modification computations for LHCD experiments on PBX-M using the TSC/LSC model

International Nuclear Information System (INIS)

Kaita, R.; Ignat, D.W.; Jardin, S.C.; Okabayashi, M.; Sun, Y.C.

1996-01-01

The TSC-LSC computational model of the dynamics of lower hybrid current drive has been exercised extensively in comparison with data from a Princeton Beta Experiment-Modification (PBX-M) discharge where the measured q(0) attained values slightly above unity. Several significant, but plausible, assumptions had to be introduced to keep the computation from behaving pathologically over time, producing singular profiles of plasma current density and q. Addition of a heuristic current diffusion estimate, or more exactly, a smoothing of the rf-driven current with a diffusion-like equation, greatly improved the behavior of the computation, and brought theory and measurement into reasonable agreement. The model was then extended to longer pulse lengths and higher powers to investigate performance to be expected in future PBX-M current profile modification experiments. copyright 1996 American Institute of Physics

Training Opportunities and Employee Exhaustion in Call Centres: Mediation by Psychological Contract Fulfilment

Science.gov (United States)

Chambel, Maria Jose; Castanheira, Filipa

2012-01-01

The aim of this study is to analyse psychological contract fulfilment as a mechanism through which training affects stress in call centres. The hypotheses were tested on a sample of 412 call centre operators, using structural equation modelling to analyse their survey responses. Our results demonstrated that training is negatively related to…

Net-erosion profile model and simulation experiments

International Nuclear Information System (INIS)

Sagara, Akio

2001-01-01

Estimation of net-erosion profile is requisite for evaluating the lifetime of divertor plates under high heat and particle fluxes of fusion plasmas. As a reference in benchmark tests of numerical calculation codes, a self-consistent analytical solution is presented for a simplified divertor condition, wherein the magnetic field line is normal to the target plate and the ionization mean free path of sputtered particles is assumed constant. The primary flux profile of hydrogen and impurities are externally given as well as the return ratio of sputtered atoms to the target. In the direction along the divertor trace, all conditions are uniform. The analytical solution is compared with net-erosion experiments carried out using the Compact Helical System (CHS). The deposition profiles of Ti and O impurities are in very good agreement with the analytical predictions. Recent preliminary results observed on divertor plates in the Large Helical Device (LHD) are briefly presented. (author)

Assimilation of Remotely Sensed Soil Moisture Profiles into a Crop Modeling Framework for Reliable Yield Estimations

Science.gov (United States)

Mishra, V.; Cruise, J.; Mecikalski, J. R.

2017-12-01

Much effort has been expended recently on the assimilation of remotely sensed soil moisture into operational land surface models (LSM). These efforts have normally been focused on the use of data derived from the microwave bands and results have often shown that improvements to model simulations have been limited due to the fact that microwave signals only penetrate the top 2-5 cm of the soil surface. It is possible that model simulations could be further improved through the introduction of geostationary satellite thermal infrared (TIR) based root zone soil moisture in addition to the microwave deduced surface estimates. In this study, root zone soil moisture estimates from the TIR based Atmospheric Land Exchange Inverse (ALEXI) model were merged with NASA Soil Moisture Active Passive (SMAP) based surface estimates through the application of informational entropy. Entropy can be used to characterize the movement of moisture within the vadose zone and accounts for both advection and diffusion processes. The Principle of Maximum Entropy (POME) can be used to derive complete soil moisture profiles and, fortuitously, only requires a surface boundary condition as well as the overall mean moisture content of the soil column. A lower boundary can be considered a soil parameter or obtained from the LSM itself. In this study, SMAP provided the surface boundary while ALEXI supplied the mean and the entropy integral was used to tie the two together and produce the vertical profile. However, prior to the merging, the coarse resolution (9 km) SMAP data were downscaled to the finer resolution (4.7 km) ALEXI grid. The disaggregation scheme followed the Soil Evaporative Efficiency approach and again, all necessary inputs were available from the TIR model. The profiles were then assimilated into a standard agricultural crop model (Decision Support System for Agrotechnology, DSSAT) via the ensemble Kalman Filter. The study was conducted over the Southeastern United States for the

Calling at the highway: The spatiotemporal constraint of road noise on Pacific chorus frog communication.

Science.gov (United States)

Nelson, Danielle V; Klinck, Holger; Carbaugh-Rutland, Alexander; Mathis, Codey L; Morzillo, Anita T; Garcia, Tiffany S

2017-01-01

Loss of acoustic habitat due to anthropogenic noise is a key environmental stressor for vocal amphibian species, a taxonomic group that is experiencing global population declines. The Pacific chorus frog ( Pseudacris regilla ) is the most common vocal species of the Pacific Northwest and can occupy human-dominated habitat types, including agricultural and urban wetlands. This species is exposed to anthropogenic noise, which can interfere with vocalizations during the breeding season. We hypothesized that Pacific chorus frogs would alter the spatial and temporal structure of their breeding vocalizations in response to road noise, a widespread anthropogenic stressor. We compared Pacific chorus frog call structure and ambient road noise levels along a gradient of road noise exposures in the Willamette Valley, Oregon, USA. We used both passive acoustic monitoring and directional recordings to determine source level (i.e., amplitude or volume), dominant frequency (i.e., pitch), call duration, and call rate of individual frogs and to quantify ambient road noise levels. Pacific chorus frogs were unable to change their vocalizations to compensate for road noise. A model of the active space and time ("spatiotemporal communication") over which a Pacific chorus frog vocalization could be heard revealed that in high-noise habitats, spatiotemporal communication was drastically reduced for an individual. This may have implications for the reproductive success of this species, which relies on specific call repertoires to portray relative fitness and attract mates. Using the acoustic call parameters defined by this study (frequency, source level, call rate, and call duration), we developed a simplified model of acoustic communication space-time for this species. This model can be used in combination with models that determine the insertion loss for various acoustic barriers to define the impact of anthropogenic noise on the radius of communication in threatened species

Control-oriented modeling of the plasma particle density in tokamaks and application to real-time density profile reconstruction

NARCIS (Netherlands)

Blanken, T.C.; Felici, F.; Rapson, C.J.; de Baar, M.R.; Heemels, W.P.M.H.

2018-01-01

A model-based approach to real-time reconstruction of the particle density profile in tokamak plasmas is presented, based on a dynamic state estimator. Traditionally, the density profile is reconstructed in real-time by solving an ill-conditioned inversion problem using a measurement at a single

Modeling of the endosperm crush response profile of hard red spring wheat using a single kernel characterization system

Science.gov (United States)

When a wheat endosperm is crushed the force profile shows viscoelastic response and the modulus of elasticity is an important parameter that might have substantial influence on wheat milling. An experiment was performed to model endosperm crush response profile (ECRP) and to determine the modulus o...

How to call the Fire Brigade

CERN Multimedia

2003-01-01

The telephone numbers for the CERN Fire Brigade are: 74444 for emergency calls 74848 for other calls Note The number 112 will stay in use for emergency calls from "wired" telephones, however, from mobile phones it leads to non-CERN emergency services.

Experimental three-dimensional beam profiling and modeling of a terahertz beam generated from a two-color air plasma

DEFF Research Database (Denmark)

Pedersen, Pernille Klarskov; Strikwerda, Andrew; Iwaszczuk, Krzysztof

2013-01-01

a sharp, conical intensity profile resembling a donut, and in the focal region the beam collapses to a central, Lorentz-shaped profile. The Lorentzian intensity profile in the focal region can be explained by considering the frequency-dependent spot size derived from measurements of the Gouy phase shift...... in the focal region, and the transition from the donut profile to a central peak is consistent with propagation of a Bessel–Gauss beam, as shown by simulations based on a recent transient photocurrent model (You et al 2012 Phys. Rev. Lett. 109 183902). We combine our measurements to the first full 3D...

Tractable flux-driven temperature, density, and rotation profile evolution with the quasilinear gyrokinetic transport model QuaLiKiz

Science.gov (United States)

Citrin, J.; Bourdelle, C.; Casson, F. J.; Angioni, C.; Bonanomi, N.; Camenen, Y.; Garbet, X.; Garzotti, L.; Görler, T.; Gürcan, O.; Koechl, F.; Imbeaux, F.; Linder, O.; van de Plassche, K.; Strand, P.; Szepesi, G.; Contributors, JET

2017-12-01

Quasilinear turbulent transport models are a successful tool for prediction of core tokamak plasma profiles in many regimes. Their success hinges on the reproduction of local nonlinear gyrokinetic fluxes. We focus on significant progress in the quasilinear gyrokinetic transport model QuaLiKiz (Bourdelle et al 2016 Plasma Phys. Control. Fusion 58 014036), which employs an approximated solution of the mode structures to significantly speed up computation time compared to full linear gyrokinetic solvers. Optimisation of the dispersion relation solution algorithm within integrated modelling applications leads to flux calculations × {10}6-7 faster than local nonlinear simulations. This allows tractable simulation of flux-driven dynamic profile evolution including all transport channels: ion and electron heat, main particles, impurities, and momentum. Furthermore, QuaLiKiz now includes the impact of rotation and temperature anisotropy induced poloidal asymmetry on heavy impurity transport, important for W-transport applications. Application within the JETTO integrated modelling code results in 1 s of JET plasma simulation within 10 h using 10 CPUs. Simultaneous predictions of core density, temperature, and toroidal rotation profiles for both JET hybrid and baseline experiments are presented, covering both ion and electron turbulence scales. The simulations are successfully compared to measured profiles, with agreement mostly in the 5%-25% range according to standard figures of merit. QuaLiKiz is now open source and available at www.qualikiz.com.

Modeling pedestrian crossing speed profiles considering speed change behavior for the safety assessment of signalized intersections.

Science.gov (United States)

Iryo-Asano, Miho; Alhajyaseen, Wael K M

2017-11-01

Pedestrian safety is one of the most challenging issues in road networks. Understanding how pedestrians maneuver across an intersection is the key to applying countermeasures against traffic crashes. It is known that the behaviors of pedestrians at signalized crosswalks are significantly different from those in ordinary walking spaces, and they are highly influenced by signal indication, potential conflicts with vehicles, and intersection geometries. One of the most important characteristics of pedestrian behavior at crosswalks is the possible sudden speed change while crossing. Such sudden behavioral change may not be expected by conflicting vehicles, which may lead to hazardous situations. This study aims to quantitatively model the sudden speed changes of pedestrians as they cross signalized crosswalks under uncongested conditions. Pedestrian speed profiles are collected from empirical data and speed change events are extracted assuming that the speed profiles are stepwise functions. The occurrence of speed change events is described by a discrete choice model as a function of the necessary walking speed to complete crossing before the red interval ends, current speed, and the presence of turning vehicles in the conflict area. The amount of speed change before and after the event is modeled using regression analysis. A Monte Carlo simulation is applied for the entire speed profile of the pedestrians. The results show that the model can represent the pedestrian travel time distribution more accurately than the constant speed model. Copyright © 2017 Elsevier Ltd. All rights reserved.

Two-state Markov-chain Poisson nature of individual cellphone call statistics

Science.gov (United States)

Jiang, Zhi-Qiang; Xie, Wen-Jie; Li, Ming-Xia; Zhou, Wei-Xing; Sornette, Didier

2016-07-01

Unfolding the burst patterns in human activities and social interactions is a very important issue especially for understanding the spreading of disease and information and the formation of groups and organizations. Here, we conduct an in-depth study of the temporal patterns of cellphone conversation activities of 73 339 anonymous cellphone users, whose inter-call durations are Weibull distributed. We find that the individual call events exhibit a pattern of bursts, that high activity periods are alternated with low activity periods. In both periods, the number of calls are exponentially distributed for individuals, but power-law distributed for the population. Together with the exponential distributions of inter-call durations within bursts and of the intervals between consecutive bursts, we demonstrate that the individual call activities are driven by two independent Poisson processes, which can be combined within a minimal model in terms of a two-state first-order Markov chain, giving significant fits for nearly half of the individuals. By measuring directly the distributions of call rates across the population, which exhibit power-law tails, we purport the existence of power-law distributions, via the ‘superposition of distributions’ mechanism. Our findings shed light on the origins of bursty patterns in other human activities.

Modeling the vertical soil organic matter profile using Bayesian parameter estimation

Directory of Open Access Journals (Sweden)

M. C. Braakhekke

2013-01-01

Full Text Available The vertical distribution of soil organic matter (SOM in the profile may constitute an important factor for soil carbon cycling. However, the formation of the SOM profile is currently poorly understood due to equifinality, caused by the entanglement of several processes: input from roots, mixing due to bioturbation, and organic matter leaching. In this study we quantified the contribution of these three processes using Bayesian parameter estimation for the mechanistic SOM profile model SOMPROF. Based on organic carbon measurements, 13 parameters related to decomposition and transport of organic matter were estimated for two temperate forest soils: an Arenosol with a mor humus form (Loobos, the Netherlands, and a Cambisol with mull-type humus (Hainich, Germany. Furthermore, the use of the radioisotope ²¹⁰Pb_ex as tracer for vertical SOM transport was studied. For Loobos, the calibration results demonstrate the importance of organic matter transport with the liquid phase for shaping the vertical SOM profile, while the effects of bioturbation are generally negligible. These results are in good agreement with expectations given in situ conditions. For Hainich, the calibration offered three distinct explanations for the observations (three modes in the posterior distribution. With the addition of ²¹⁰Pb_ex data and prior knowledge, as well as additional information about in situ conditions, we were able to identify the most likely explanation, which indicated that root litter input is a dominant process for the SOM profile. For both sites the organic matter appears to comprise mainly adsorbed but potentially leachable material, pointing to the importance of organo-mineral interactions. Furthermore, organic matter in the mineral soil appears to be mainly derived from root litter, supporting previous studies that highlighted the importance of root input for soil carbon sequestration. The ²¹⁰

MicroRNA Profiling Reveals Marker of Motor Neuron Disease in ALS Models.

Science.gov (United States)

Hoye, Mariah L; Koval, Erica D; Wegener, Amy J; Hyman, Theodore S; Yang, Chengran; O'Brien, David R; Miller, Rebecca L; Cole, Tracy; Schoch, Kathleen M; Shen, Tao; Kunikata, Tomonori; Richard, Jean-Philippe; Gutmann, David H; Maragakis, Nicholas J; Kordasiewicz, Holly B; Dougherty, Joseph D; Miller, Timothy M

2017-05-31

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder marked by the loss of motor neurons (MNs) in the brain and spinal cord, leading to fatally debilitating weakness. Because this disease predominantly affects MNs, we aimed to characterize the distinct expression profile of that cell type to elucidate underlying disease mechanisms and to identify novel targets that inform on MN health during ALS disease time course. microRNAs (miRNAs) are short, noncoding RNAs that can shape the expression profile of a cell and thus often exhibit cell-type-enriched expression. To determine MN-enriched miRNA expression, we used Cre recombinase-dependent miRNA tagging and affinity purification in mice. By defining the in vivo miRNA expression of MNs, all neurons, astrocytes, and microglia, we then focused on MN-enriched miRNAs via a comparative analysis and found that they may functionally distinguish MNs postnatally from other spinal neurons. Characterizing the levels of the MN-enriched miRNAs in CSF harvested from ALS models of MN disease demonstrated that one miRNA (miR-218) tracked with MN loss and was responsive to an ALS therapy in rodent models. Therefore, we have used cellular expression profiling tools to define the distinct miRNA expression of MNs, which is likely to enrich future studies of MN disease. This approach enabled the development of a novel, drug-responsive marker of MN disease in ALS rodents. SIGNIFICANCE STATEMENT Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease in which motor neurons (MNs) in the brain and spinal cord are selectively lost. To develop tools to aid in our understanding of the distinct expression profiles of MNs and, ultimately, to monitor MN disease progression, we identified small regulatory microRNAs (miRNAs) that were highly enriched or exclusive in MNs. The signal for one of these MN-enriched miRNAs is detectable in spinal tap biofluid from an ALS rat model, where its levels change as disease

Air puff-induced 22-kHz calls in F344 rats.

Science.gov (United States)

Inagaki, Hideaki; Sato, Jun

2016-03-01

Air puff-induced ultrasonic vocalizations in adult rats, termed "22-kHz calls," have been applied as a useful animal model to develop psychoneurological and psychopharmacological studies focusing on human aversive affective disorders. To date, all previous studies on air puff-induced 22-kHz calls have used outbred rats. Furthermore, newly developed gene targeting technologies, which are essential for further advancement of biomedical experiments using air puff-induced 22-kHz calls, have enabled the production of genetically modified rats using inbred rat strains. Therefore, we considered it necessary to assess air puff-induced 22-kHz calls in inbred rats. In this study, we assessed differences in air puff-induced 22-kHz calls between inbred F344 rats and outbred Wistar rats. Male F344 rats displayed similar total (summed) duration of air puff-induced 22 kHz vocalizations to that of male Wistar rats, however, Wistar rats emitted fewer calls of longer duration, while F344 rats emitted higher number of vocalizations of shorter duration. Additionally, female F344 rats emitted fewer air puff-induced 22-kHz calls than did males, thus confirming the existence of a sex difference that was previously reported for outbred Wistar rats. The results of this study could confirm the reliability of air puff stimulus for induction of a similar amount of emissions of 22-kHz calls in different rat strains, enabling the use of air puff-induced 22-kHz calls in inbred F344 rats and derived genetically modified animals in future studies concerning human aversive affective disorders. Copyright © 2015 Elsevier Inc. All rights reserved.

Household electricity demand profiles

DEFF Research Database (Denmark)

Marszal, Anna Joanna; Heiselberg, Per Kvols; Larsen, Olena Kalyanova

2016-01-01

Highlights •A 1-min resolution household electricity load model is presented. •Model adapts a bottom-up approach with single appliance as the main building block. •Load profiles are used to analyse the flexibility potential of household appliances. •Load profiles can be applied in other domains, .......g. building energy simulations. •The demand level of houses with different number of occupants is well captured....

Maximum-likelihood model averaging to profile clustering of site types across discrete linear sequences.

Directory of Open Access Journals (Sweden)

Zhang Zhang

2009-06-01

Full Text Available A major analytical challenge in computational biology is the detection and description of clusters of specified site types, such as polymorphic or substituted sites within DNA or protein sequences. Progress has been stymied by a lack of suitable methods to detect clusters and to estimate the extent of clustering in discrete linear sequences, particularly when there is no a priori specification of cluster size or cluster count. Here we derive and demonstrate a maximum likelihood method of hierarchical clustering. Our method incorporates a tripartite divide-and-conquer strategy that models sequence heterogeneity, delineates clusters, and yields a profile of the level of clustering associated with each site. The clustering model may be evaluated via model selection using the Akaike Information Criterion, the corrected Akaike Information Criterion, and the Bayesian Information Criterion. Furthermore, model averaging using weighted model likelihoods may be applied to incorporate model uncertainty into the profile of heterogeneity across sites. We evaluated our method by examining its performance on a number of simulated datasets as well as on empirical polymorphism data from diverse natural alleles of the Drosophila alcohol dehydrogenase gene. Our method yielded greater power for the detection of clustered sites across a breadth of parameter ranges, and achieved better accuracy and precision of estimation of clusters, than did the existing empirical cumulative distribution function statistics.

Campbell's monkeys concatenate vocalizations into context-specific call sequences

Science.gov (United States)

Ouattara, Karim; Lemasson, Alban; Zuberbühler, Klaus

2009-01-01

Primate vocal behavior is often considered irrelevant in modeling human language evolution, mainly because of the caller's limited vocal control and apparent lack of intentional signaling. Here, we present the results of a long-term study on Campbell's monkeys, which has revealed an unrivaled degree of vocal complexity. Adult males produced six different loud call types, which they combined into various sequences in highly context-specific ways. We found stereotyped sequences that were strongly associated with cohesion and travel, falling trees, neighboring groups, nonpredatory animals, unspecific predatory threat, and specific predator classes. Within the responses to predators, we found that crowned eagles triggered four and leopards three different sequences, depending on how the caller learned about their presence. Callers followed a number of principles when concatenating sequences, such as nonrandom transition probabilities of call types, addition of specific calls into an existing sequence to form a different one, or recombination of two sequences to form a third one. We conclude that these primates have overcome some of the constraints of limited vocal control by combinatorial organization. As the different sequences were so tightly linked to specific external events, the Campbell's monkey call system may be the most complex example of ‘proto-syntax’ in animal communication known to date. PMID:20007377

Using Semantic Similarity In Automated Call Quality Evaluator For Call Centers

Directory of Open Access Journals (Sweden)

Ria A. Sagum

2015-08-01

Full Text Available Conversation between the agent and client are being evaluated manually by a quality assurance officer QA. This job is only one of the responsibilities being done by a QA and particularly eat ups a lot of time for them which lead to late evaluation results that may cause untimely response of the company to concerns raised by their clients. This research developed an application software that automates and evaluates the quality assurance in business process outsourcing companies or customer service management implementing sentence similarity. The developed system includes two modules speaker diarization which includes transcription and question and answer extraction and similarity checker which checks the similarity between the extracted answer and the answer of the call center agent to a question. The system was evaluated for Correctness of the extracted answers and accurateness of the evaluation for a particular call. Audio conversations were tested for the accuracy of the transcription module which has an accuracy of 27.96. The Precision Recall and F-measure of the extracted answer was tested as 78.03 96.26 and 86.19 respectively. The Accuracy of the system in evaluating a call is 70.

Predictive integrated modelling for ITER scenarios

International Nuclear Information System (INIS)

Artaud, J.F.; Imbeaux, F.; Aniel, T.; Basiuk, V.; Eriksson, L.G.; Giruzzi, G.; Hoang, G.T.; Huysmans, G.; Joffrin, E.; Peysson, Y.; Schneider, M.; Thomas, P.

2005-01-01

The uncertainty on the prediction of ITER scenarios is evaluated. 2 transport models which have been extensively validated against the multi-machine database are used for the computation of the transport coefficients. The first model is GLF23, the second called Kiauto is a model in which the profile of dilution coefficient is a gyro Bohm-like analytical function, renormalized in order to get profiles consistent with a given global energy confinement scaling. The package of codes CRONOS is used, it gives access to the dynamics of the discharge and allows the study of interplay between heat transport, current diffusion and sources. The main motivation of this work is to study the influence of parameters such plasma current, heat, density, impurities and toroidal moment transport. We can draw the following conclusions: 1) the target Q = 10 can be obtained in ITER hybrid scenario at I p = 13 MA, using either the DS03 two terms scaling or the GLF23 model based on the same pedestal; 2) I p = 11.3 MA, Q = 10 can be reached only assuming a very peaked pressure profile and a low pedestal; 3) at fixed Greenwald fraction, Q increases with density peaking; 4) achieving a stationary q-profile with q > 1 requires a large non-inductive current fraction (80%) that could be provided by 20 to 40 MW of LHCD; and 5) owing to the high temperature the q-profile penetration is delayed and q = 1 is reached about 600 s in ITER hybrid scenario at I p = 13 MA, in the absence of active q-profile control. (A.C.)

Sedimentation dynamics and equilibrium profiles in multicomponent mixtures of colloidal particles

International Nuclear Information System (INIS)

Spruijt, E; Biesheuvel, P M

2014-01-01

In this paper we give a general theoretical framework that describes the sedimentation of multicomponent mixtures of particles with sizes ranging from molecules to macroscopic bodies. Both equilibrium sedimentation profiles and the dynamic process of settling, or its converse, creaming, are modeled. Equilibrium profiles are found to be in perfect agreement with experiments. Our model reconciles two apparently contradicting points of view about buoyancy, thereby resolving a long-lived paradox about the correct choice of the buoyant density. On the one hand, the buoyancy force follows necessarily from the suspension density, as it relates to the hydrostatic pressure gradient. On the other hand, sedimentation profiles of colloidal suspensions can be calculated directly using the fluid density as apparent buoyant density in colloidal systems in sedimentation–diffusion equilibrium (SDE) as a result of balancing gravitational and thermodynamic forces. Surprisingly, this balance also holds in multicomponent mixtures. This analysis resolves the ongoing debate of the correct choice of buoyant density (fluid or suspension): both approaches can be used in their own domain. We present calculations of equilibrium sedimentation profiles and dynamic sedimentation that show the consequences of these insights. In bidisperse mixtures of colloids, particles with a lower mass density than the homogeneous suspension will first cream and then settle, whereas particles with a suspension-matched mass density form transient, bimodal particle distributions during sedimentation, which disappear when equilibrium is reached. In all these cases, the centers of the distributions of the particles with the lowest mass density of the two, regardless of their actual mass, will be located in equilibrium above the so-called isopycnic point, a natural consequence of their hard-sphere interactions. We include these interactions using the Boublik–Mansoori–Carnahan–Starling–Leland (BMCSL

Profile control simulations and experiments on TCV : A controller test environment and results using a model-based predictive controller

NARCIS (Netherlands)

Maljaars, E.; Felici, F.; Blanken, T.C.; Galperti, C.; Sauter, O.; de Baar, M.R.; Carpanese, F.; Goodman, T.P.; Kim, D.; Kim, S.H.; Kong, M.G.; Mavkov, B.; Merle, A.; Moret, J.M.; Nouailletas, R.; Scheffer, M.; Teplukhina, A.A.; Vu, N.M.T.

2017-01-01

The successful performance of a model predictive profile controller is demonstrated in simulations and experiments on the TCV tokamak, employing a profile controller test environment. Stable high-performance tokamak operation in hybrid and advanced plasma scenarios requires control over the safety

Profile control simulations and experiments on TCV: a controller test environment and results using a model-based predictive controller

NARCIS (Netherlands)

Maljaars, B.; Felici, F.; Blanken, T. C.; Galperti, C.; Sauter, O.; de Baar, M. R.; Carpanese, F.; Goodman, T. P.; Kim, D.; Kim, S. H.; Kong, M.; Mavkov, B.; Merle, A.; Moret, J.; Nouailletas, R.; Scheffer, M.; Teplukhina, A.; Vu, T.

2017-01-01

The successful performance of a model predictive profile controller is demonstrated in simulations and experiments on the TCV tokamak, employing a profile controller test environment. Stable high-performance tokamak operation in hybrid and advanced plasma scenarios requires control over the safety

Calling in Work: Secular or Sacred?

Science.gov (United States)

Steger, Michael F.; Pickering, N. K.; Shin, J. Y.; Dik, B. J.

2010-01-01

Recent scholarship indicates that people who view their work as a calling are more satisfied with their work and their lives. Historically, calling has been regarded as a religious experience, although modern researchers frequently have adopted a more expansive and secular conceptualization of calling, emphasizing meaning and personal fulfillment…

Fluid and gyrokinetic modelling of particle transport in plasmas with hollow density profiles

International Nuclear Information System (INIS)

Tegnered, D; Oberparleiter, M; Nordman, H; Strand, P

2016-01-01

Hollow density profiles occur in connection with pellet fuelling and L to H transitions. A positive density gradient could potentially stabilize the turbulence or change the relation between convective and diffusive fluxes, thereby reducing the turbulent transport of particles towards the center, making the fuelling scheme inefficient. In the present work, the particle transport driven by ITG/TE mode turbulence in regions of hollow density profiles is studied by fluid as well as gyrokinetic simulations. The fluid model used, an extended version of the Weiland transport model, Extended Drift Wave Model (EDWM), incorporates an arbitrary number of ion species in a multi-fluid description, and an extended wavelength spectrum. The fluid model, which is fast and hence suitable for use in predictive simulations, is compared to gyrokinetic simulations using the code GENE. Typical tokamak parameters are used based on the Cyclone Base Case. Parameter scans in key plasma parameters like plasma β, R/L T , and magnetic shear are investigated. It is found that β in particular has a stabilizing effect in the negative R/L n region, both nonlinear GENE and EDWM show a decrease in inward flux for negative R/L n and a change of direction from inward to outward for positive R/L n . This might have serious consequences for pellet fuelling of high β plasmas. (paper)

Application of Cognitive and Socio-Cultural Theories in CALL

Directory of Open Access Journals (Sweden)

Mustafa Akın Güngör

2011-06-01

Full Text Available Since it is quite difficult in traditional learning atmospheres for the learners to be exposed to the target language adequately in foreign language acquisition, CALL in which virtual environment is designed in more appropriate way has given rise. Two main paradigms, cognitive model and socio-cultural theory, have also been adopted in CALL. Moreover, rather than applying one theory, combination of these paradigms is unavoidable. However, application of this combination is challenging in practice, as these two theories have different principles. Furthermore, when it comes to online education, it turns into more challenging process. In this poster this combination is presented with the help of sample applications from Gazi University.

Hornbills can distinguish between primate alarm calls.

Science.gov (United States)

Rainey, Hugo J.; Zuberbühler, Klaus; Slater, Peter J. B.

2004-01-01

Some mammals distinguish between and respond appropriately to the alarm calls of other mammal and bird species. However, the ability of birds to distinguish between mammal alarm calls has not been investigated. Diana monkeys (Cercopithecus diana) produce different alarm calls to two predators: crowned eagles (Stephanoaetus coronatus) and leopards (Panthera pardus). Yellow-casqued hornbills (Ceratogymna elata) are vulnerable to predation by crowned eagles but are not preyed on by leopards and might therefore be expected to respond to the Diana monkey eagle alarm call but not to the leopard alarm call. We compared responses of hornbills to playback of eagle shrieks, leopard growls, Diana monkey eagle alarm calls and Diana monkey leopard alarm calls and found that they distinguished appropriately between the two predator vocalizations as well as between the two Diana monkey alarm calls. We discuss possible mechanisms leading to these responses. PMID:15209110

Modelling of the electron density height profiles in the mid-latitude ionospheric D-region

Directory of Open Access Journals (Sweden)

P. Y. Mukhtarov

1996-06-01

Full Text Available A new mid-latitude D-region (50-105 km model of the electron density is presented obtained on the basis of a full wave theory and by a trial-and-error inversion method. Daytime (at different solar zenith angles absorption measurements by A3-technique made in Bulgaria yielded data with the aid of which the seasonal and diurnal courses of the Ne(h-profiles were derived. Special attention is drawn to the event diurnal asymmetry, or uneven formation of the ionosphere as a function of insulation. The latter is probably connected with the influence of the diurnal fluctuations in the local temperature on the chemistry involved in the electron loss rate, as well as the diurnal variations of the main ionizing agent (NO in the D-region. That is why the Ne(h-profiles in the midlatitude D-region are modelled separately for morning and afternoon hours.

Call for proposals for the Joint Canada-Israel Health Research ...

International Development Research Centre (IDRC) Digital Library (Canada)

23 nov. 2017 ... Call for proposals for the Joint Canada-Israel Health Research Program 2018 competition ... developmental neurobiology; neuro-immunology; neuroendocrinology; regenerative medicine in brain disease; cellular and molecular basis of cognition; modeling brain function; imaging of neural processes ...

Psychometric properties of the Plutchik's EPI test (Emotions Profile Index

Directory of Open Access Journals (Sweden)

Ana Trebovc

2005-04-01

Full Text Available Authors report a study on psychometric properties of Plutchik's test, called Emotions Profile Index (EPI. A new Slovene translation and adaptation of English version of the test, consisting of combinations (pairs of 12 words reflecting eight different emotional conditions, was prepared and compared to the old one. Both versions as well as the Big Five Questionnaire (BFQ were administered on the sample of 239 participants. Different statistical analyses were performed examining psychometric features of both versions of EPI. Discriminative power was tested by cluster analysis and analysis of frequency distributions, reliability was studied via internal consistency index and correlation between the two versions, and validity was examined by correlating PIE dimensions with BFQ dimensions and subdimensions, by comparing profiles of groups on both versions of EPI and BFQ and by fitting the theoretical model proposed by Plutchik to the data. Discriminative power of EPI seems to be affected by avoiding (not choosing the socially desirable expressions in the test, parallel reliability seems to be susceptible to the use of different words (expressions in the new version of EPI having the same meaning as words in the old version. Dimensions expected to reflect similar constructs in BFQ and EPI do not correlate satisfactory. Data gathered with EPI cannot be fully explained with the model proposed by Plutchik's theory.

Investigating the Correspondence Between Transcriptomic and Proteomic Expression Profiles Using Coupled Cluster Models

International Nuclear Information System (INIS)

Rogers, Simon; Girolami, Mark; Kolch, Walter; Waters, Katrina M.; Liu, Tao; Thrall, Brian D.; Wiley, H. S.

2008-01-01

Modern transcriptomics and proteomics enable us to survey the expression of RNAs and proteins at large scales. While these data are usually generated and analyzed separately, there is an increasing interest in comparing and co-analyzing transcriptome and proteome expression data. A major open question is whether transcriptome and proteome expression is linked and how it is coordinated. Results: Here we have developed a probabilistic clustering model that permits analysis of the links between transcriptomic and proteomic profiles in a sensible and flexible manner. Our coupled mixture model defines a prior probability distribution over the component to which a protein profile should be assigned conditioned on which component the associated mRNA profile belongs to. By providing probabilistic assignments this approach sits between the two extremes of concatenating the data on the assumption that mRNA and protein clusters would have a one-to-one relationship, and independent clustering where the mRNA profile provides no information on the protein profile and vice-versa. We apply this approach to a large dataset of quantitative transcriptomic and proteomic expression data obtained from a human breast epithelial cell line (HMEC) stimulated by epidermal growth factor (EGF) over a series of timepoints corresponding to one cell cycle. The results reveal a complex relationship between transcriptome and proteome with most mRNA clusters linked to at least two protein clusters, and vice versa. A more detailed analysis incorporating information on gene function from the gene ontology database shows that a high correlation of mRNA and protein expression is limited to the components of some molecular machines, such as the ribosome, cell adhesion complexes and the TCP-1 chaperonin involved in protein folding. Conclusions: The dynamic regulation of the transcriptome and proteome in mammalian cells in response to an acute mitogenic stimulus appears largely independent with very little

Effect of practical training on the learning motivation profile of Japanese pharmacy students using structural equation modeling

Directory of Open Access Journals (Sweden)

Shigeo Yamamura

2017-02-01

Full Text Available Purpose To establish a model of Japanese pharmacy students’ learning motivation profile and investigate the effects of pharmaceutical practical training programs on their learning motivation. Methods The Science Motivation Questionnaire II was administered to pharmacy students in their 4th (before practical training, 5th (before practical training at clinical sites, and 6th (after all practical training years of study at Josai International University in April, 2016. Factor analysis and multiple-group structural equation modeling were conducted for data analysis. Results A total of 165 students participated. The learning motivation profile was modeled with 4 factors (intrinsic, career, self-determination, and grade motivation, and the most effective learning motivation was grade motivation. In the multiple-group analysis, the fit of the model with the data was acceptable, and the estimated mean value of the factor of ‘self-determination’ in the learning motivation profile increased after the practical training programs (P= 0.048, Cohen’s d= 0.43. Conclusion Practical training programs in a 6-year course were effective for increasing learning motivation, based on ‘self-determination’ among Japanese pharmacy students. The results suggest that practical training programs are meaningful not only for providing clinical experience but also for raising learning motivation.

Driving profile modeling and recognition based on soft computing approach.

Science.gov (United States)

Wahab, Abdul; Quek, Chai; Tan, Chin Keong; Takeda, Kazuya

2009-04-01

Advancements in biometrics-based authentication have led to its increasing prominence and are being incorporated into everyday tasks. Existing vehicle security systems rely only on alarms or smart card as forms of protection. A biometric driver recognition system utilizing driving behaviors is a highly novel and personalized approach and could be incorporated into existing vehicle security system to form a multimodal identification system and offer a greater degree of multilevel protection. In this paper, detailed studies have been conducted to model individual driving behavior in order to identify features that may be efficiently and effectively used to profile each driver. Feature extraction techniques based on Gaussian mixture models (GMMs) are proposed and implemented. Features extracted from the accelerator and brake pedal pressure were then used as inputs to a fuzzy neural network (FNN) system to ascertain the identity of the driver. Two fuzzy neural networks, namely, the evolving fuzzy neural network (EFuNN) and the adaptive network-based fuzzy inference system (ANFIS), are used to demonstrate the viability of the two proposed feature extraction techniques. The performances were compared against an artificial neural network (NN) implementation using the multilayer perceptron (MLP) network and a statistical method based on the GMM. Extensive testing was conducted and the results show great potential in the use of the FNN for real-time driver identification and verification. In addition, the profiling of driver behaviors has numerous other potential applications for use by law enforcement and companies dealing with buses and truck drivers.

Interactionability in Computer Game: Call of Duty

Directory of Open Access Journals (Sweden)

masoud Kowsari

2009-11-01

Full Text Available For a long time communication theorists have criticized public media for being unilateral. What they prescript is to transform pattern of communication into bilateral one; in other words, to make media interactional. Telephone is the first fully interactional, however, there was a long road to the contemporary communication and information media which are highly interactional. Nevertheless, not all the modern media are equally interactional. Therefore, it is necessary to evaluate levels of interactionability in modern media and strength them. As other concepts in communication, interaction has different definitions, implying various aspects of the audience-media relation. And this feature of multi-dimensionality is to be considered. Quistis (2002 suggests a model in which all the technical, social, and comprehensive aspects of interaction are inherent. In other words, not only the technical aspect of media, but also audience’s perception plays a key role in the model. Visual-computer games are good instance of interactionability in modern media. However, not all games are equally interactional. Analyzing a well-known computer game “Call of Duty”, this article attempts to study different levels of interactionability. The main question is: how can one offer a pragmatic definition of three dimensions of interactionability to study computer games; and how this features are in Call of Duty applied?

Human Non-linguistic Vocal Repertoire: Call Types and Their Meaning.

Science.gov (United States)

Anikin, Andrey; Bååth, Rasmus; Persson, Tomas

2018-01-01

Recent research on human nonverbal vocalizations has led to considerable progress in our understanding of vocal communication of emotion. However, in contrast to studies of animal vocalizations, this research has focused mainly on the emotional interpretation of such signals. The repertoire of human nonverbal vocalizations as acoustic types, and the mapping between acoustic and emotional categories, thus remain underexplored. In a cross-linguistic naming task (Experiment 1), verbal categorization of 132 authentic (non-acted) human vocalizations by English-, Swedish- and Russian-speaking participants revealed the same major acoustic types: laugh, cry, scream, moan, and possibly roar and sigh. The association between call type and perceived emotion was systematic but non-redundant: listeners associated every call type with a limited, but in some cases relatively wide, range of emotions. The speed and consistency of naming the call type predicted the speed and consistency of inferring the caller's emotion, suggesting that acoustic and emotional categorizations are closely related. However, participants preferred to name the call type before naming the emotion. Furthermore, nonverbal categorization of the same stimuli in a triad classification task (Experiment 2) was more compatible with classification by call type than by emotion, indicating the former's greater perceptual salience. These results suggest that acoustic categorization may precede attribution of emotion, highlighting the need to distinguish between the overt form of nonverbal signals and their interpretation by the perceiver. Both within- and between-call acoustic variation can then be modeled explicitly, bringing research on human nonverbal vocalizations more in line with the work on animal communication.

Genotype calling in tetraploid species from bi-allelic marker data using mixture models

NARCIS (Netherlands)

Voorrips, R.E.; Gort, G.; Vosman, B.

2011-01-01

Background: Automated genotype calling in tetraploid species was until recently not possible, which hampered genetic analysis. Modern genotyping assays often produce two signals, one for each allele of a bi-allelic marker. While ample software is available to obtain genotypes (homozygous for either

Mechanism Profiling of Hepatotoxicity Caused by Oxidative Stress Using Antioxidant Response Element Reporter Gene Assay Models and Big Data.

Science.gov (United States)

Kim, Marlene Thai; Huang, Ruili; Sedykh, Alexander; Wang, Wenyi; Xia, Menghang; Zhu, Hao

2016-05-01

Hepatotoxicity accounts for a substantial number of drugs being withdrawn from the market. Using traditional animal models to detect hepatotoxicity is expensive and time-consuming. Alternative in vitro methods, in particular cell-based high-throughput screening (HTS) studies, have provided the research community with a large amount of data from toxicity assays. Among the various assays used to screen potential toxicants is the antioxidant response element beta lactamase reporter gene assay (ARE-bla), which identifies chemicals that have the potential to induce oxidative stress and was used to test > 10,000 compounds from the Tox21 program. The ARE-bla computational model and HTS data from a big data source (PubChem) were used to profile environmental and pharmaceutical compounds with hepatotoxicity data. Quantitative structure-activity relationship (QSAR) models were developed based on ARE-bla data. The models predicted the potential oxidative stress response for known liver toxicants when no ARE-bla data were available. Liver toxicants were used as probe compounds to search PubChem Bioassay and generate a response profile, which contained thousands of bioassays (> 10 million data points). By ranking the in vitro-in vivo correlations (IVIVCs), the most relevant bioassay(s) related to hepatotoxicity were identified. The liver toxicants profile contained the ARE-bla and relevant PubChem assays. Potential toxicophores for well-known toxicants were created by identifying chemical features that existed only in compounds with high IVIVCs. Profiling chemical IVIVCs created an opportunity to fully explore the source-to-outcome continuum of modern experimental toxicology using cheminformatics approaches and big data sources. Kim MT, Huang R, Sedykh A, Wang W, Xia M, Zhu H. 2016. Mechanism profiling of hepatotoxicity caused by oxidative stress using antioxidant response element reporter gene assay models and big data. Environ Health Perspect 124:634-641;�

New fuzzy EWMA control charts for monitoring phase II fuzzy profiles

Directory of Open Access Journals (Sweden)

Ghazale Moghadam

2016-01-01

Full Text Available In many quality control applications, the quality of a process or product is explained by the relationship between response variable and one or more explanatory variables, called a profile. In this paper, a new fuzzy EWMA control chart for phase II fuzzy profile monitoring is proposed. To this end, we extend EWMA control charts to its equivalent Fuzzy type and then implement fuzzy ranking methods to determine whether the process fuzzy profile is under or out of control. The proposed method is capable of identifying small changes in process under condition of process profile explaining parameters vagueness, roughness and uncertainty. Determining the source of changes, this method provides us with the possibility of recognizing the causes of process transition from stable mode, removing these causes and restoring the process stable mode.

Peafowl antipredator calls encode information about signalers.

Science.gov (United States)

Yorzinski, Jessica L

2014-02-01

Animals emit vocalizations that convey information about external events. Many of these vocalizations, including those emitted in response to predators, also encode information about the individual that produced the call. The relationship between acoustic features of antipredator calls and information relating to signalers (including sex, identity, body size, and social rank) were examined in peafowl (Pavo cristatus). The "bu-girk" antipredator calls of male and female peafowl were recorded and 20 acoustic parameters were automatically extracted from each call. Both the bu and girk elements of the antipredator call were individually distinctive and calls were classified to the correct signaler with over 90% and 70% accuracy in females and males, respectively. Females produced calls with a higher fundamental frequency (F0) than males. In both females and males, body size was negatively correlated with F0. In addition, peahen rank was related to the duration, end mean frequency, and start harmonicity of the bu element. Peafowl antipredator calls contain detailed information about the signaler and can potentially be used by receivers to respond to dangerous situations.

Injury Profile SIMulator, a qualitative aggregative modelling framework to predict crop injury profile as a function of cropping practices, and the abiotic and biotic environment. I. Conceptual bases.

Directory of Open Access Journals (Sweden)

Jean-Noël Aubertot

Full Text Available The limitation of damage caused by pests (plant pathogens, weeds, and animal pests in any agricultural crop requires integrated management strategies. Although significant efforts have been made to i develop, and to a lesser extent ii combine genetic, biological, cultural, physical and chemical control methods in Integrated Pest Management (IPM strategies (vertical integration, there is a need for tools to help manage Injury Profiles (horizontal integration. Farmers design cropping systems according to their goals, knowledge, cognition and perception of socio-economic and technological drivers as well as their physical, biological, and chemical environment. In return, a given cropping system, in a given production situation will exhibit a unique injury profile, defined as a dynamic vector of the main injuries affecting the crop. This simple description of agroecosystems has been used to develop IPSIM (Injury Profile SIMulator, a modelling framework to predict injury profiles as a function of cropping practices, abiotic and biotic environment. Due to the tremendous complexity of agroecosystems, a simple holistic aggregative approach was chosen instead of attempting to couple detailed models. This paper describes the conceptual bases of IPSIM, an aggregative hierarchical framework and a method to help specify IPSIM for a given crop. A companion paper presents a proof of concept of the proposed approach for a single disease of a major crop (eyespot on wheat. In the future, IPSIM could be used as a tool to help design ex-ante IPM strategies at the field scale if coupled with a damage sub-model, and a multicriteria sub-model that assesses the social, environmental, and economic performances of simulated agroecosystems. In addition, IPSIM could also be used to help make diagnoses on commercial fields. It is important to point out that the presented concepts are not crop- or pest-specific and that IPSIM can be used on any crop.

Injury Profile SIMulator, a qualitative aggregative modelling framework to predict crop injury profile as a function of cropping practices, and the abiotic and biotic environment. I. Conceptual bases.

Science.gov (United States)

Aubertot, Jean-Noël; Robin, Marie-Hélène

2013-01-01

The limitation of damage caused by pests (plant pathogens, weeds, and animal pests) in any agricultural crop requires integrated management strategies. Although significant efforts have been made to i) develop, and to a lesser extent ii) combine genetic, biological, cultural, physical and chemical control methods in Integrated Pest Management (IPM) strategies (vertical integration), there is a need for tools to help manage Injury Profiles (horizontal integration). Farmers design cropping systems according to their goals, knowledge, cognition and perception of socio-economic and technological drivers as well as their physical, biological, and chemical environment. In return, a given cropping system, in a given production situation will exhibit a unique injury profile, defined as a dynamic vector of the main injuries affecting the crop. This simple description of agroecosystems has been used to develop IPSIM (Injury Profile SIMulator), a modelling framework to predict injury profiles as a function of cropping practices, abiotic and biotic environment. Due to the tremendous complexity of agroecosystems, a simple holistic aggregative approach was chosen instead of attempting to couple detailed models. This paper describes the conceptual bases of IPSIM, an aggregative hierarchical framework and a method to help specify IPSIM for a given crop. A companion paper presents a proof of concept of the proposed approach for a single disease of a major crop (eyespot on wheat). In the future, IPSIM could be used as a tool to help design ex-ante IPM strategies at the field scale if coupled with a damage sub-model, and a multicriteria sub-model that assesses the social, environmental, and economic performances of simulated agroecosystems. In addition, IPSIM could also be used to help make diagnoses on commercial fields. It is important to point out that the presented concepts are not crop- or pest-specific and that IPSIM can be used on any crop.

BUFO PARDALIS (ANURA: BUFONIDAE): MATING CALL AND ...

African Journals Online (AJOL)

the calls of one of these species, Bufo pardalis. Hewitt, were not analysed by Tandy & Keith. (1972). Furthennore there is some confusion in the literature regarding the mating call of this species. For these reasons this mating call is here clarified. The mating call of B. pardaiis was first described by Ranger (in Hewitt 1935) as ...

Initial development of an automated task analysis profiling system

International Nuclear Information System (INIS)

Jorgensen, C.C.

1984-01-01

A program for automated task analysis is described. Called TAPS (task analysis profiling system), the program accepts normal English prose and outputs skills, knowledges, attitudes, and abilities (SKAAs) along with specific guidance and recommended ability measurement tests for nuclear power plant operators. A new method for defining SKAAs is presented along with a sample program output

Comparison of collisional radiative models for edge electron density reconstruction from Li I (2s-2p) emission profiles

Energy Technology Data Exchange (ETDEWEB)

Stoschus, H.; Hudson, B.; Munoz Burgos, J. M. [Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee 37831-0117 (United States); Thomas, D. M. [General Atomics, San Diego, California 92186-5608 (United States); Schweinzer, J. [Max-Planck-Institut fuer Plasmaphysik, Euratom Association, 85748 Garching (Germany)

2012-10-15

Four collisional radiative models (CRMs) for reconstruction of the edge electron density profile from the measured Li I (2s-2p) emission profile of an accelerated lithium beam are compared using experimental data from DIII-D. It is shown for both L- and H-mode plasmas that edge density profiles reconstructed with the CRMs DDD2, ABSOLUT, [Sasaki et al. Rev. Sci. Instrum. 64, 1699 (1993)] and a new model developed at DIII-D agree in a density scan from n{sub e}{sup ped}= (2.0-6.5) Multiplication-Sign 10{sup 19} m{sup -3} within 20%, 20%, <5%, and 40%, respectively, of the pedestal density measured with Thomson scattering. Profile shape and absolute density vary in a scan of the effective ion charge Z{sub eff}= 1-6 up to a factor of two but agree with Thomson data for Z{sub eff}= 1-2 within the error bars.

Effects of fueling profiles on plasma transport

International Nuclear Information System (INIS)

Houlberg, W.A.; Mense, A.T.; Attenberger, S.E.; Milora, S.L.

1977-01-01

The effects of cold particle fueling profiles on particle and energy transport in an ignition sized tokamak plasma are investigated in this study with a one-dimensional, multifluid transport model. A density gradient driven trapped particle microinstability model for plasma transport is used to demonstrate potential effects of fueling profiles on ignition requirements. Important criteria for the development of improved transport models under the conditions of shallow particle fueling profiles are outlined. A discrete pellet fueling model indicates that large fluctuations in density and temperature may occur in the outer regions of the plasma with large, shallowly penetrating pellets, but fluctuations in the pressure profile are small. The hot central core of the plasma remains unaffected by the large fluctuations near the plasma edge

To females of a noctuid moth, male courtship songs are nothing more than bat echolocation calls

DEFF Research Database (Denmark)

Nakano, Ryo; Takanashi, Takuma; Skals, Niels

2010-01-01

It has been proposed that intraspecific ultrasonic communication observed in some moths evolved, through sexual selection, subsequent to the development of ears sensitive to echolocation calls of insectivorous bats. Given this scenario, the receiver bias model of signal evolution argues that acou......It has been proposed that intraspecific ultrasonic communication observed in some moths evolved, through sexual selection, subsequent to the development of ears sensitive to echolocation calls of insectivorous bats. Given this scenario, the receiver bias model of signal evolution argues...... production in the male moth, and subsequently the role of the sound with reference to the female's ability to discriminate male courtship songs from bat calls. We found that males have sex-specific tymbals for ultrasound emission, and that the broadcast of either male songs or simulated bat calls equally...

External GSM phone calls now made simpler

CERN Multimedia

2007-01-01

On 2 July, the IT/CS Telecom Service introduced a new service making external calls from CERN GSM phones easier. A specific prefix is no longer needed for calls outside CERN. External calls from CERN GSM phones are to be simplified. It is no longer necessary to use a special prefix to call an external number from the CERN GSM network.The Telecom Section of the IT/CS Group is introducing a new system that will make life easier for GSM users. It is no longer necessary to use a special prefix (333) to call an external number from the CERN GSM network. Simply dial the number directly like any other Swiss GSM customer. CERN currently has its own private GSM network with the Swiss mobile operator, Sunrise, covering the whole of Switzerland. This network was initially intended exclusively for calls between CERN numbers (replacing the old beeper system). A special system was later introduced for external calls, allowing them to pass thr...

Processing and evaluation of x-ray line profiles measured from nanostructured materials produced by severe plastic deformation

International Nuclear Information System (INIS)

KEXrber, M.; Schafler, E.; Zehetbauer, M.

2005-01-01

Full text: The classification of the microstructure of nanostructured materials and its relation to macroscopic properties is essential for the development and application of nanomaterials. X-ray line profile analysis is a nondestructive method yielding a series of interesting microstructural parameters: the Bragg reflection of an ideal crystal is a narrow delta-function liKEX peak. Distortions of the regular crystal lattice as well as a finite size of the coherently scattering domains lead to a significant broadening of the peak. By using physical models describing the individual types of broadening it is possible to relate the broadening of the peak to the microstructure of the material. The most successful applications to date assume mainly size and strain broadening. From these models various techniques have been developed to evaluate the same physical quantities via individual methods. Among these methods are the Williamson-Hall and Warren Averbach methods, their so called 'modified' variants and multiple-whole-profile-fitting/modeling. A number of typical problems arising during data preparation and evaluation are presented and a procedure to optimize the processing of the experimental data is given. Refs. 9 (author)

Sharing programming resources between Bio* projects through remote procedure call and native call stack strategies.

Science.gov (United States)

Prins, Pjotr; Goto, Naohisa; Yates, Andrew; Gautier, Laurent; Willis, Scooter; Fields, Christopher; Katayama, Toshiaki

2012-01-01

Open-source software (OSS) encourages computer programmers to reuse software components written by others. In evolutionary bioinformatics, OSS comes in a broad range of programming languages, including C/C++, Perl, Python, Ruby, Java, and R. To avoid writing the same functionality multiple times for different languages, it is possible to share components by bridging computer languages and Bio* projects, such as BioPerl, Biopython, BioRuby, BioJava, and R/Bioconductor. In this chapter, we compare the two principal approaches for sharing software between different programming languages: either by remote procedure call (RPC) or by sharing a local call stack. RPC provides a language-independent protocol over a network interface; examples are RSOAP and Rserve. The local call stack provides a between-language mapping not over the network interface, but directly in computer memory; examples are R bindings, RPy, and languages sharing the Java Virtual Machine stack. This functionality provides strategies for sharing of software between Bio* projects, which can be exploited more often. Here, we present cross-language examples for sequence translation, and measure throughput of the different options. We compare calling into R through native R, RSOAP, Rserve, and RPy interfaces, with the performance of native BioPerl, Biopython, BioJava, and BioRuby implementations, and with call stack bindings to BioJava and the European Molecular Biology Open Software Suite. In general, call stack approaches outperform native Bio* implementations and these, in turn, outperform RPC-based approaches. To test and compare strategies, we provide a downloadable BioNode image with all examples, tools, and libraries included. The BioNode image can be run on VirtualBox-supported operating systems, including Windows, OSX, and Linux.

Modeled Radar Attenuation Rate Profile at the Vostok 5G Ice Core Site, Antarctica, Version 1

Data.gov (United States)

National Aeronautics and Space Administration — This data set provides a modeled radar attenuation rate profile, showing the predicted contributions from pure ice and impurities to radar attenuation at the Vostok...

Call Duration Characteristics based on Customers Location

Directory of Open Access Journals (Sweden)

Žvinys Karolis

2014-05-01

Full Text Available Nowadays a lot of different researches are performed based on call duration distributions (CDD analysis. However, the majority of studies are linked with social relationships between the people. Therefore the scarcity of information, how the call duration is associated with a user's location, is appreciable. The goal of this paper is to reveal the ties between user's voice call duration and the location of call. For this reason we analyzed more than 5 million calls from real mobile network, which were made over the base stations located in rural areas, roads, small towns, business and entertainment centers, residential districts. According to these site types CDD’s and characteristic features for call durations are given and discussed. Submitted analysis presents the users habits and behavior as a group (not an individual. The research showed that CDD’s of customers being them in different locations are not equal. It has been found that users at entertainment, business centers are tend to talk much shortly, than people being at home. Even more CDD can be distorted strongly, when machinery calls are evaluated. Hence to apply a common CDD for a whole network it is not recommended. The study also deals with specific parameters of call duration for distinguished user groups, the influence of network technology for call duration is considered.

ORCHIDEE-SOM: modeling soil organic carbon (SOC) and dissolved organic carbon (DOC) dynamics along vertical soil profiles in Europe

Science.gov (United States)

Camino-Serrano, Marta; Guenet, Bertrand; Luyssaert, Sebastiaan; Ciais, Philippe; Bastrikov, Vladislav; De Vos, Bruno; Gielen, Bert; Gleixner, Gerd; Jornet-Puig, Albert; Kaiser, Klaus; Kothawala, Dolly; Lauerwald, Ronny; Peñuelas, Josep; Schrumpf, Marion; Vicca, Sara; Vuichard, Nicolas; Walmsley, David; Janssens, Ivan A.

2018-03-01

Current land surface models (LSMs) typically represent soils in a very simplistic way, assuming soil organic carbon (SOC) as a bulk, and thus impeding a correct representation of deep soil carbon dynamics. Moreover, LSMs generally neglect the production and export of dissolved organic carbon (DOC) from soils to rivers, leading to overestimations of the potential carbon sequestration on land. This common oversimplified processing of SOC in LSMs is partly responsible for the large uncertainty in the predictions of the soil carbon response to climate change. In this study, we present a new soil carbon module called ORCHIDEE-SOM, embedded within the land surface model ORCHIDEE, which is able to reproduce the DOC and SOC dynamics in a vertically discretized soil to 2 m. The model includes processes of biological production and consumption of SOC and DOC, DOC adsorption on and desorption from soil minerals, diffusion of SOC and DOC, and DOC transport with water through and out of the soils to rivers. We evaluated ORCHIDEE-SOM against observations of DOC concentrations and SOC stocks from four European sites with different vegetation covers: a coniferous forest, a deciduous forest, a grassland, and a cropland. The model was able to reproduce the SOC stocks along their vertical profiles at the four sites and the DOC concentrations within the range of measurements, with the exception of the DOC concentrations in the upper soil horizon at the coniferous forest. However, the model was not able to fully capture the temporal dynamics of DOC concentrations. Further model improvements should focus on a plant- and depth-dependent parameterization of the new input model parameters, such as the turnover times of DOC and the microbial carbon use efficiency. We suggest that this new soil module, when parameterized for global simulations, will improve the representation of the global carbon cycle in LSMs, thus helping to constrain the predictions of the future SOC response to global

The use of soil moisture - remote sensing products for large-scale groundwater modeling and assessment

NARCIS (Netherlands)

Sutanudjaja, E.H.

2012-01-01

In this thesis, the possibilities of using spaceborne remote sensing for large-scale groundwater modeling are explored. We focus on a soil moisture product called European Remote Sensing Soil Water Index (ERS SWI, Wagner et al., 1999) - representing the upper profile soil moisture. As a test-bed, we

Strong profiling is not mathematically optimal for discovering rare malfeasors

Energy Technology Data Exchange (ETDEWEB)

Press, William H [Los Alamos National Laboratory

2008-01-01

In a large population of individuals labeled j = 1,2,...,N, governments attempt to find the rare malfeasor j = j, (terrorist, for example) by making use of priors p{sub j} that estimate the probability of individual j being a malfeasor. Societal resources for secondary random screening such as airport search or police investigation are concentrated against individuals with the largest priors. They may call this 'strong profiling' if the concentration is at least proportional to p{sub j} for the largest values. Strong profiling often results in higher probability, but otherwise innocent, individuals being repeatedly subjected to screening. They show here that, entirely apart from considerations of social policy, strong profiling is not mathematically optimal at finding malfeasors. Even if prior probabilities were accurate, their optimal use would be only as roughly the geometric mean between a strong profiling and a completely uniform sampling of the population.

Forward and backscatter dose profile to diagnostic X-rays at gold/tissue interfaces

International Nuclear Information System (INIS)

Rosa, Luiz A.R. da; Seidenbusch, Michael; Regulla, Dieter F.

1997-01-01

The radiological and clinical significance of dose distributions in the vicinity of media interfaces in radiotherapy and the complex nature of these dose distributions have long been recognised. A possible dosimetry method for dose profile assessment near interfaces is the use of the so-called thermally stimulated exoelectron emission (TSEE) dosemeter. In this work the possibility of using Be O/TSEE dosimeters to assess the forward and backscatter dose profile at the interface soft tissue/gold was investigated for diagnostic heavily filtered X-rays spectrum A-60 of ISO Standard A-quality. Dose and range profiles are presented. (author). 14 refs., 3 figs

Landscape correlates along mourning dove call-count routes in Mississippi

Science.gov (United States)

Elmore, R.D.; Vilella, F.J.; Gerard, P.D.

2007-01-01

Mourning dove (Zenaida macroura) call-count surveys in Mississippi, USA, suggest declining populations. We used available mourning dove call-count data to evaluate long-term mourning dove habitat relationships. Dove routes were located in the Mississippi Alluvial Valley, Deep Loess Province, Mid Coastal Plain, and Hilly Coastal Plain physiographic provinces of Mississippi. We also included routes in the Blackbelt Prairie region of Mississippi and Alabama, USA. We characterized landscape structure and composition within 1.64-km buffers around 10 selected mourning dove call-count routes during 3 time periods. Habitat classes included agriculture, forest, urban, regeneration stands, wetland, and woodlot. We used Akaike's Information Criterion to select the best candidate model. We selected a model containing percent agriculture and edge density that contained approximately 40% of the total variability in the data set. Percent agriculture was positively correlated with relative dove abundance. Interestingly, we found a negative relationship between edge density and dove abundance. Researchers should conduct future research on dove nesting patterns in Mississippi and threshold levels of edge necessary to maximize dove density. During the last 20 years, Mississippi lost more than 800,000 ha of cropland while forest cover represented largely by pine (Pinus taeda) plantations increased by more than 364,000 ha. Our results suggest observed localized declines in mourning dove abundance in Mississippi may be related to the documented conversion of agricultural lands to pine plantations.

The role of drug profiles as similarity metrics: applications to repurposing, adverse effects detection and drug-drug interactions.

Science.gov (United States)

Vilar, Santiago; Hripcsak, George

2017-07-01

Explosion of the availability of big data sources along with the development in computational methods provides a useful framework to study drugs' actions, such as interactions with pharmacological targets and off-targets. Databases related to protein interactions, adverse effects and genomic profiles are available to be used for the construction of computational models. In this article, we focus on the description of biological profiles for drugs that can be used as a system to compare similarity and create methods to predict and analyze drugs' actions. We highlight profiles constructed with different biological data, such as target-protein interactions, gene expression measurements, adverse effects and disease profiles. We focus on the discovery of new targets or pathways for drugs already in the pharmaceutical market, also called drug repurposing, in the interaction with off-targets responsible for adverse reactions and in drug-drug interaction analysis. The current and future applications, strengths and challenges facing all these methods are also discussed. Biological profiles or signatures are an important source of data generation to deeply analyze biological actions with important implications in drug-related studies. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Green vessel scheduling in liner shipping: Modeling carbon dioxide emission costs in sea and at ports of call

Directory of Open Access Journals (Sweden)

Maxim A. Dulebenets

2018-03-01

Full Text Available Considering a substantial increase in volumes of the international seaborne trade and drastic climate changes due to carbon dioxide emissions, liner shipping companies have to improve planning of their vessel schedules and improve energy efficiency. This paper presents a novel mixed integer non-linear mathematical model for the green vessel scheduling problem, which directly accounts for the carbon dioxide emission costs in sea and at ports of call. The original non-linear model is linearized and then solved using CPLEX. A set of numerical experiments are conducted for a real-life liner shipping route to reveal managerial insights that can be of importance to liner shipping companies. Results indicate that the proposed mathematical model can serve as an efficient planning tool for liner shipping companies and may assist with evaluation of various carbon dioxide taxation schemes. Increasing carbon dioxide tax may substantially change the design of vessel schedules, incur additional route service costs, and improve the environmental sustainability. However, the effects from increasing carbon dioxide tax on the marine container terminal operations are found to be very limited.

Burnout syndrome and weekly workload of on-call physicians: cross-sectional study

Directory of Open Access Journals (Sweden)

Fabiano Timbó Barbosa

Full Text Available CONTEXT AND OBJECTIVES: Burnout syndrome (BS is characterized by three dimensions: emotional exhaustion, depersonalization and reduced personal fulfillment. The objectives of this study were to evaluate a possible association between BS and weekly workload, and to describe the prevalence of BS and the sociodemographic and occupational profile of on-call physicians in Maceió. DESIGN AND SETTING: Cross-sectional study in intensive care units (ICU at public and private hospitals in Maceió. METHODS: A self-administered form was used to evaluate sociodemographic characteristics and BS through the Maslach Burnout Inventory (MBI among 67 on-call physicians at ICUs in Maceió. Pearson's R correlation test was used to compare workload and emotional exhaustion. For other dimensions, Spearman's S test was used (P < 0.05. Other variables were represented by simple frequencies. The 95% confidence interval was calculated for each variable. RESULTS: Among the physicians studied, 55.22% were female and the mean age was 43.9 ± 8.95 years. The mean weekly workload on call was 43.85 ± 24.49 hours. The frequency of high scores in at least one of the three dimensions of MBI was 70.14%. CONCLUSIONS: Despite the high prevalence of BS, especially among physicians who did not practice regular physical activity, our data did not indicate any significant correlation between weekly workload and any of the three dimensions of BS in this sample. The high prevalence of BS draws attention to the importance of investigating other possible causes, in order to prevent and adequately treat it.

Device Modeling of the Performance of Cu(In,GaSe2 Solar Cells with V-Shaped Bandgap Profiles

Directory of Open Access Journals (Sweden)

Shou-Yi Kuo

2014-01-01

Full Text Available The effect of Cu(In,GaSe2 (CIGS with V-shaped bandgap on device performance is investigated in detail. A series of Ga/(In+Ga ratio are set to study the influence of V-shaped bandgap profile on the electricity of CIGS thin film solar cells. The modeling of device current density-voltage (J-V curve and bandgap grading profile corresponded well to measurement results. Detailed characteristic and modeling results show that an increased gradient of bandgap from valley to the buffer layer CdS will result in a barrier and lead to an enhanced recombination in the valley. This phenomenon can be modified by the back electric field resulting from a gradient bandgap from valley (bandgap minimum to the Mo back contact. These results indicate CIGS-based solar cells can achieve higher performance by optimizing the V-shaped bandgap profile.

Performance of flash profile and napping with and without training for describing small sensory differences in a model wine

DEFF Research Database (Denmark)

Liu, Jing; Grønbeck, Marlene Schou; Di Monaco, Rosella

2016-01-01

. In this study different variations of two rapid sensory methods, one based on holistic assessment – Napping, and one based on attribute evaluation – Flash Profile, were tested for the evaluation of the flavour in wine. Model wines were developed with control over the sensory differences in terms of sensory...... to arrange samples on the sheet) or the product (familiarisation with the sensory properties of the wines) improved the outcome compared to the classical Napping protocol. The classical Flash Profile protocol and its modified version including a Napping with subsequent attributes generation as the word...... generation step and limiting the number of attributes for ranking gave a similar sample space. The Napping method could best highlight qualitative sample differences, whereas the Flash Profile provided a more precise product mapping on quantitative differences between model wines....

Care and Calls

DEFF Research Database (Denmark)

Paasch, Bettina Sletten

on the enactment of care but also on patient safety. Nurses working in various hospital departments have developed different strategies for handling mobile phone calls when with a patient. Additional research into the ways nurses successfully or unsuccessfully enact care and ensure patient safety when they answer......In Danish hospitals, nurses have been equipped with a mobile work phone to improve their availability and efficiency. On the phones nurses receive internal and external phone conversations, patient calls, and alarms from electronic surveillance equipment. For safety reasons the phones cannot...... be switched off or silenced; they consequently ring during all activities and also during interactions with patients. A possible tension thus arises when nurses have to be both caring and sensitive towards the patient and simultaneously be efficient and available and answer their phone. The present paper...

Calling under pressure: short-finned pilot whales make social calls during deep foraging dives.

Science.gov (United States)

Jensen, Frants H; Perez, Jacobo Marrero; Johnson, Mark; Soto, Natacha Aguilar; Madsen, Peter T

2011-10-22

Toothed whales rely on sound to echolocate prey and communicate with conspecifics, but little is known about how extreme pressure affects pneumatic sound production in deep-diving species with a limited air supply. The short-finned pilot whale (Globicephala macrorhynchus) is a highly social species among the deep-diving toothed whales, in which individuals socialize at the surface but leave their social group in pursuit of prey at depths of up to 1000 m. To investigate if these animals communicate acoustically at depth and test whether hydrostatic pressure affects communication signals, acoustic DTAGs logging sound, depth and orientation were attached to 12 pilot whales. Tagged whales produced tonal calls during deep foraging dives at depths of up to 800 m. Mean call output and duration decreased with depth despite the increased distance to conspecifics at the surface. This shows that the energy content of calls is lower at depths where lungs are collapsed and where the air volume available for sound generation is limited by ambient pressure. Frequency content was unaffected, providing a possible cue for group or species identification of diving whales. Social calls may be important to maintain social ties for foraging animals, but may be impacted adversely by vessel noise.

Plasma microRNA profiles in rat models of hepatocellular injury, cholestasis, and steatosis.

Directory of Open Access Journals (Sweden)

Yu Yamaura

Full Text Available MicroRNAs (miRNAs are small RNA molecules that function to modulate the expression of target genes, playing important roles in a wide range of physiological and pathological processes. The miRNAs in body fluids have received considerable attention as potential biomarkers of various diseases. In this study, we compared the changes of the plasma miRNA expressions by acute liver injury (hepatocellular injury or cholestasis and chronic liver injury (steatosis, steatohepatitis and fibrosis using rat models made by the administration of chemicals or special diets. Using miRNA array analysis, we found that the levels of a large number of miRNAs (121-317 miRNAs were increased over 2-fold and the levels of a small number of miRNAs (6-35 miRNAs were decreased below 0.5-fold in all models except in a model of cholestasis caused by bile duct ligation. Interestingly, the expression profiles were different between the models, and the hierarchical clustering analysis discriminated between the acute and chronic liver injuries. In addition, miRNAs whose expressions were typically changed in each type of liver injury could be specified. It is notable that, in acute liver injury models, the plasma level of miR-122, the most abundant miRNA in the liver, was more quickly and dramatically increased than the plasma aminotransferase level, reflecting the extent of hepatocellular injury. This study demonstrated that the plasma miRNA profiles could reflect the types of liver injury (e.g. acute/chronic liver injury or hepatocellular injury/cholestasis/steatosis/steatohepatitis/fibrosis and identified the miRNAs that could be specific and sensitive biomarkers of liver injury.

Do market participants learn from conference calls?

NARCIS (Netherlands)

Roelofsen, E.; Verbeeten, F.; Mertens, G.

2014-01-01

We examine whether market participants learn from the information that is disseminated during the Q-and-A section of conference calls. Specifically, we investigate whether stock prices react to information on intangible assets provided during conference calls, and whether conference calls

The Optimal Design Method and Standardized Mathematical Model of Tooth Profile Modification of Spur Gear

Directory of Open Access Journals (Sweden)

Wenjie Mei

2016-01-01

Full Text Available The paper reports a tooth profile modification method of spur gear. After establishing a standardized mathematical model for optimized tooth profile and simulating meshing process with ANSYS finite element analysis, we obtained 625 groups of gear models with different modification parameters. The group with minimum transmission errors owns the optimal parameters. Genetic algorithm was adopted in the entire process for the purpose of reducing the variation of transmission errors in meshing process. The arc and parabolic modification were doing the same processing. After comparing the transmission errors fluctuation produced by the meshing process of gear of nonmodification with arc modification and parabolic modification, we found that the best modification effects of arc modification and parabolic modification were both reduced by 90%. The modification method makes the gear drive process more stable and efficient, and it is also promising in general application for gear drive.

The impact of transitioning from a 24-hour to a 16-hour call model amongst a cohort of Canadian anesthesia residents at McMaster University – a survey study

Directory of Open Access Journals (Sweden)

Sussman D

2015-08-01

Full Text Available David Sussman, James E Paul Department of Anesthesia, McMaster University, Hamilton, ON, Canada Purpose: The primary objective of this study was to assess anesthesia residents' opinions and perceptions on wellness/burnout, fatigue, education, and patient safety after the initiation of a reduced call model (16-hour call. Methods: A prospective cohort study was conducted at three time points during the 2013–2014 academic year. A web-based questionnaire consisting of 23 questions was electronically distributed to all anesthesia residents from postgraduate years (PGY 1 to 5 who were part of the active call roster (n=84 at McMaster University in Hamilton, Ontario. Descriptive summaries were calculated, counts and percentages were used for categorical variables, and answers to open text questions were reviewed for themes. Results: A response rate of 67% was obtained for this study. A majority of anesthesia residents (65% approved of 16-hour call, felt that their overall quality of life as a senior resident (PGY3 or greater or junior resident (PGY2 and below had improved (73% and 55%, respectively, and reported overall feeling less fatigued. Most respondents indicated that the quality of education remained unchanged (47%, or had improved (31%. And most felt better prepared for the royal college exam (52%. Most felt patient safety had improved or was unchanged (both 48%. Conclusion: The study demonstrates that 16-hour call improved resident wellness, reduced burnout and fostered an environment where residents are less fatigued and more satisfied with their educational experience promoting an environment of patient safety. Overall, the anesthesia residency group demonstrated that not only is 16-hour call preferred but beneficial. Keywords: resident wellness, reduced call model, duty hours, patient safety, cohort study, fatigue 

A statistical approach to plasma profile analysis

International Nuclear Information System (INIS)

Kardaun, O.J.W.F.; McCarthy, P.J.; Lackner, K.; Riedel, K.S.

1990-05-01

A general statistical approach to the parameterisation and analysis of tokamak profiles is presented. The modelling of the profile dependence on both the radius and the plasma parameters is discussed, and pertinent, classical as well as robust, methods of estimation are reviewed. Special attention is given to statistical tests for discriminating between the various models, and to the construction of confidence intervals for the parameterised profiles and the associated global quantities. The statistical approach is shown to provide a rigorous approach to the empirical testing of plasma profile invariance. (orig.)

HOW TO CALL THE CERN FIRE BRIGADE

CERN Multimedia

2002-01-01

The telephone numbers of the CERN Fire Brigade are: 74444 for emergency calls 74848 for other calls Note The number 112 will stay in use for emergency calls from 'wired' telephones, however, from mobile phones it leads to non-CERN emergency services.  

HOW TO CALL THE CERN FIRE BRIGADE

CERN Multimedia

2002-01-01

The telephone numbers of the CERN Fire Brigade are: 74444 for emergency calls 74848 for other calls Note The number 112 will stay in use for emergency calls from 'wired' telephones, however, from mobile phones it leads to non-CERN emergency services.

HOW TO CALL THE CERN FIRE BRIGADE

CERN Multimedia

2001-01-01

The telephone numbers of the CERN Fire Brigade are: 74444 for emergency calls 74848 for other calls Note The number 112 will stay in use for emergency calls from 'wired' telephones, however, from mobile phones it leads to non-CERN emergency services.

HOW TO CALL THE CERN FIRE BRIGADE

CERN Multimedia

2001-01-01

The telephone numbers of the CERN Fire Brigade are: 74444 for emergency calls 74848 for other calls Note: the number 112 will stay in use for emergency calls from 'wired' telephones, however, from mobile phones it leads to non-CERN emergency services.

Application of Physiologically Based Absorption Modeling to Characterize the Pharmacokinetic Profiles of Oral Extended Release Methylphenidate Products in Adults.

Directory of Open Access Journals (Sweden)

Xiaoxia Yang

Full Text Available A previously presented physiologically-based pharmacokinetic model for immediate release (IR methylphenidate (MPH was extended to characterize the pharmacokinetic behaviors of oral extended release (ER MPH formulations in adults for the first time. Information on the anatomy and physiology of the gastrointestinal (GI tract, together with the biopharmaceutical properties of MPH, was integrated into the original model, with model parameters representing hepatic metabolism and intestinal non-specific loss recalibrated against in vitro and in vivo kinetic data sets with IR MPH. A Weibull function was implemented to describe the dissolution of different ER formulations. A variety of mathematical functions can be utilized to account for the engineered release/dissolution technologies to achieve better model performance. The physiological absorption model tracked well the plasma concentration profiles in adults receiving a multilayer-release MPH formulation or Metadate CD, while some degree of discrepancy was observed between predicted and observed plasma concentration profiles for Ritalin LA and Medikinet Retard. A local sensitivity analysis demonstrated that model parameters associated with the GI tract significantly influenced model predicted plasma MPH concentrations, albeit to varying degrees, suggesting the importance of better understanding the GI tract physiology, along with the intestinal non-specific loss of MPH. The model provides a quantitative tool to predict the biphasic plasma time course data for ER MPH, helping elucidate factors responsible for the diverse plasma MPH concentration profiles following oral dosing of different ER formulations.

Effects of airgun sounds on bowhead whale calling rates: evidence for two behavioral thresholds.

Directory of Open Access Journals (Sweden)

Susanna B Blackwell

Full Text Available In proximity to seismic operations, bowhead whales (Balaena mysticetus decrease their calling rates. Here, we investigate the transition from normal calling behavior to decreased calling and identify two threshold levels of received sound from airgun pulses at which calling behavior changes. Data were collected in August-October 2007-2010, during the westward autumn migration in the Alaskan Beaufort Sea. Up to 40 directional acoustic recorders (DASARs were deployed at five sites offshore of the Alaskan North Slope. Using triangulation, whale calls localized within 2 km of each DASAR were identified and tallied every 10 minutes each season, so that the detected call rate could be interpreted as the actual call production rate. Moreover, airgun pulses were identified on each DASAR, analyzed, and a cumulative sound exposure level was computed for each 10-min period each season (CSEL10-min. A Poisson regression model was used to examine the relationship between the received CSEL10-min from airguns and the number of detected bowhead calls. Calling rates increased as soon as airgun pulses were detectable, compared to calling rates in the absence of airgun pulses. After the initial increase, calling rates leveled off at a received CSEL10-min of ~94 dB re 1 μPa2-s (the lower threshold. In contrast, once CSEL10-min exceeded ~127 dB re 1 μPa2-s (the upper threshold, whale calling rates began decreasing, and when CSEL10-min values were above ~160 dB re 1 μPa2-s, the whales were virtually silent.