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  1. Francesco Fiorentino (ed., Figure e forme della memoria culturale

    Directory of Open Access Journals (Sweden)

    Paola Di Gennaro

    2012-12-01

    Full Text Available Lavorare la memoria, obliare, ricordare, riscrivere il passato con gli strumenti del presente, è questo il soggetto e l’oggetto dei saggi riuniti in questo volume da Francesco Fiorentino, che li introduce attraverso l’operazione artistica di Robert Rauschenberg, il quale, dopo aver chiesto un disegno a de Kooning, maestro dell’Espressionismo astratto, lo espone cancellato. Questa «sottile meditazione iconologica sul tempo edipico dell’arte moderna» (7-8 annuncia uno dei leitmotiv del volume, verità ovvia ma necessaria: se la novità ha valore estetico, come è vero dal Settecento, allora il passato diventa fondamentale come sistema interno dell’arte. È su questo necessario filtro di selezione che agiscono le memorie citate nei saggi seguenti: intersezioni di tracce e cancellazioni, di cui si indagano autenticità, costruzione, ricostruzione, senza che i confini siano tra l’altro mai definiti – ed è questo, forse, che crea l’arte, per suo mezzo e scopo, tramite l’inaffidabilità della memoria: arte che è, come il quadro di Rauschenberg, «rappresentazione della permanenza e, insieme, dell’inattingibilità di ciò che è cancellato» (11. È insomma la «dimensione performativa dell’agire culturale» che viene messa in evidenza in questo volume, memoria che è culturale, appunto, umana e storica, e che, come il Wunderblock di Freud, si cancella ma mai completamente, e mai innocuamente. L’irriconoscibilità finale del ricordo rappresenta quindi il risultato della dimenticanza, e il suo prodotto più creativo. È proprio l’infedeltà della memoria a renderla oggetto sostanziale dell’arte, così come di questo lavoro, oggetto autoriflessivo della memoria collettiva.

  2. Flange Curling in Cold Formed Profiles

    DEFF Research Database (Denmark)

    Jönsson, Jeppe; Ramonas, Gediminas

    2012-01-01

    The non-linear flange curling phenomenon in cold formed profiles is the tendency of slender flanges to deform towards the neutral axis for increasing flexural curvature. Based on Braziers work, Winter proposed a simple engineering formula for determination of the local flange deformation towards...

  3. Suicide bombers form a new injury profile.

    Science.gov (United States)

    Aharonson-Daniel, Limor; Klein, Yoram; Peleg, Kobi

    2006-12-01

    Recent explosions of suicide bombers introduced new and unique profiles of injury. Explosives frequently included small metal parts, increasing severity of injuries, challenging both physicians and healthcare systems. Timely detonation in crowded and confined spaces further increased explosion effect. Israel National Trauma Registry data on hospitalized terror casualties between October 1, 2000 and December 31, 2004 were analyzed. A total of 1155 patients injured by explosion were studied. Nearly 30% suffered severe to critical injuries (ISS > or = 16); severe injuries (AIS > or = 3) were more prevalent than in other trauma. Triage has changed as metal parts contained in bombs penetrate the human body with great force and may result in tiny entry wounds easily concealed by hair, clothes etc. A total of 36.6% had a computed tomography (CT), 26.8% had ultrasound scanning, and 53.2% had an x-ray in the emergency department. From the emergency department, 28.3% went directly to the operating room, 10.1% to the intensive care unit, and 58.4% directly to the ward. Injuries were mostly internal, open wounds, and burns, with an excess of injuries to nerves and to blood vessels compared with other trauma mechanisms. A high rate of surgical procedures was recorded, including thoracotomies, laparotomies, craniotomies, and vascular surgery. In certain cases, there were simultaneous multiple injuries that required competing forms of treatment, such as burns and blast lung. Bombs containing metal fragments detonated by suicide bombers in crowded locations change patterns and severity of injury in a civil population. Specific injuries will require tailored approaches, an open mind, and close collaboration and cooperation between trauma surgeons to share experience, opinions, and ideas. Findings presented have implications for triage, diagnosis, treatment, hospital organization, and the definition of surge capacity.

  4. Characterization of adjectival -ed and -ing forms of psychological verbs in English

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    Matsui Chie

    2017-03-01

    Full Text Available This study examines for the first time a very large set of psychological verbs and their derived adjectives in English. To determine whether an item is an adjective or not, we take the standard structural criteria of morphological (-ly or un-, morpho-syntactic (very, -er/-est or more/most and syntactic (seem, look, or feel characteristics. As for the data, we selected three data bases and gathered those containing certain items in specific contexts, such as whether the item in question takes a -ly or un- affix, or a comparative or superlative form, or follows seem, look or feel. We took dictionaries as our source of criteria in checking whether an item was perceived to be an adjective. As a result, we found some hierarchy within adjectives as to whether they take morphological, morpho-syntactic, or syntactic characteristics. The most powerful determinant of adjectives is the morphological characteristic -ly.

  5. Serum cytokine profile in the subclinical form of visceral leishmaniasis

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    Gama M.E.A.

    2004-01-01

    Full Text Available The factors determining the development or not of visceral leishmaniasis (VL have not been completely identified, but a Leishmania-specific cellular immune response seems to play a fundamental role in the final control of infection. Few studies are available regarding the production of cytokines in the subclinical form of VL, with only the production of IFN-g and TNF-a known. The aim of the present study was to identify immunological markers for the oligosymptomatic or subclinical form of VL. A prospective cohort study was conducted on 784 children aged 0 to 5 years from an endemic area in the State of Maranhão, Brazil, between January 1998 and December 2001. During 30 consecutive months of follow-up, 33 children developed the oligosymptomatic form of the disease and 12 the acute form. During the clinical manifestations, serum cytokine levels were determined in 27 oligosymptomatic children and in nine patients with the acute form using a quantitative sandwich enzyme immunoassay. In the subclinical form of VL, variable levels of IL-2 were detected in 52.3% of the children, IL-12 in 85.2%, IFN-g in 48.1%, IL-10 in 88.9%, and TNF-a in 100.0%, with the last two cytokines showing significantly lower levels than in the acute form. IL-4 was not detected in oligosymptomatic individuals. Multiple discriminant analysis used to determine the profile or combination of cytokines predominating in the subclinical form revealed both a Leishmania resistance (Th1 and susceptibility (Th2 profile. The detection of both Th1 and Th2 cytokine profiles explains the self-limited evolution accompanied by the discrete alterations observed for the subclinical form of VL.

  6. Determination of the inorganic components in the Brazilian medicinal plants from 'in natura' and capsule forms, using X-ray fluorescence techniques (WD and ED systems). Quantitative inorganic profile definition; Determinacao de componentes inorganicos em plantas medicinais, comercializadas em formas de po (capsulas) e 'in natura', utilizando a tecnica de fluorescencia de raios X por dispersao de comprimento de onda (WDXRF) e por dispersao de energia (EDXRF). Definicao de perfis inorganicos quantitativos

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, Manuel Octavio Marques

    2004-07-01

    The Na, Mg, P, S, CI, K, Ca, Mn, Fe, Ni, Cu, Zn, Rb and Sr concentrations in the Stryphnodendron barbatiman (Barbatimao), Malva officinalis (Malva), Salvia officinalis (Salvia), Ginkgo folium (Ginkgo biloba), Echinodorus macrophylius (Chapeu de couro), Paulina cupana (Guarana), Valeriana officinalis (Valeriana), Cordia salicifolia (Porangaba), Calendula officinalis (Calendula), Solidago microglossa (Arnica), Arnica montana (Arnica) and Schinus molle (Aroeira) species were concentrations. The specimens were sampled 'in natura' (leaves, flowers, barks and seeds) and capsule (powder) forms from different commercial labels. The elemental determination was outlined by wavelength dispersive (WDXRF) and energy dispersive (EDXRF) X-ray fluorescence techniques using, respectively, linear regression and fundamental parameter methods. The repeatability and accuracy of the methods were evaluated using the certified reference material NIST 1547 - 'Peach Leaves'. Statistical treatments, such as Chauvenet and Cochrane, ANOVA and Z-score tests, were applied. A quantitative inorganic profile was obtained for each specie from 'in natura' and capsule forms. Different inorganic compositions were observed in the different parts (leaves, flowers, barks and seeds) of the Schinus molle (Aroeira), Arnica montana (Arnica), Calendula officinalis (Calendula) and Echinodorus macrophylius (Chapeu de couro) species. (author)

  7. Omofobia ed eterosessismo nei contesti educativi. Le forme, le specificità e le strategie di intervento

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    Gabriele Prati

    2011-06-01

    Full Text Available In adolescent environments there are frequent occurrences of aggressive verbal and physical behaviour regarding homosexuality. In these situations young boys are motivated by a series of complex contributory factors such as difficulty in finding significant adults who are prepared to discuss sexuality; the growth and role of gender; group dynamics – how the perception that power over others is something that guarantees success and immediate social integration; the cultural and social dimension such as the legitimisation of hostility in institutional discourse. Homophobia in educational contexts can create a series of negative consequences not only for the victims, but also for the perpetrators who represent a challenge for teachers and educators. Various forms and examples of homophobia found in social discourse and adolescent behaviour are illustrated here and possible strategies for intervention are outlined along with proposals aimed at promoting respect for human diversity and mitigating contempt and dehumanisation.

  8. Robotics as science (re)form: Exploring power, learning and gender(ed) identity formation in a "community of practice"

    Science.gov (United States)

    Hurner, Sheryl Marie

    "Robotics as Science (re)Form" utilizes qualitative research methods to examine the career trajectories and gender identity formation of female youth participating as members of an all-girl, academic team within the male-dominated environment of the FIRST Robotics competition. Following the constant comparative approach (Glaser & Strauss, 1967), my project relies upon triangulating ethnographic data drawn from extensive field notes, semi-structured interviews, and digital and video imagery compiled over two years of participant observation. Drawing upon the sociolinguistic "community of practice" (CoP) framework (Eckert & McConnell-Ginet, 1992; Lave & Wenger, 1991; Wenger, 1998), this study maps the range of gendered "identities" available to girls involved in non-traditional academic and occupational pursuits within a local context, and reveals the nature, structure and impact of power operating within this CoP, a significantly underdeveloped construct within the language and gender literature. These research findings (1) contribute to refining theories of situated or problem based learning with a focus on female youth (Lave & Wenger, 1991; Wenger, 1998); (2) reveal affordances and barriers within the local program design that enable (and preclude) women and minority youth entering the engineering pipeline; and (3) enrich our understanding of intragroup language and gendered "practices" to counter largely essentializing generalizations based upon quantitative analysis. Keywords: Robotics, gender, identity formation, science, STEM, communities of practice

  9. Equilibrium Temperature Profiles within Fission Product Waste Forms

    Energy Technology Data Exchange (ETDEWEB)

    Kaminski, Michael D. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-10-01

    We studied waste form strategies for advanced fuel cycle schemes. Several options were considered for three waste streams with the following fission products: cesium and strontium, transition metals, and lanthanides. These three waste streams may be combined or disposed separately. The decay of several isotopes will generate heat that must be accommodated by the waste form, and this heat will affect the waste loadings. To help make an informed decision on the best option, we present computational data on the equilibrium temperature of glass waste forms containing a combination of these three streams.

  10. Depth contours for NOS Chart 11013, 39th Ed., 1992-04-25 for South Florida, Cuba, and the Bahamas in GIS vector form (NODC Accession 0000459)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — GIS line coverage of depth contours (bathymetry) for the area shown in National Ocean Service (NOS) chart 11013, 39th Ed., 25 Apr 1992. Area covers South Florida,...

  11. The origin of rotation profiles in star-forming clouds

    Science.gov (United States)

    Takahashi, Sanemichi Z.; Tomida, Kengo; Machida, Masahiro N.; Inutsuka, Shu-ichiro

    2016-12-01

    The angular momentum distribution and its redistribution are of crucial importance in the formation and evolution of circumstellar discs. Many molecular line observations towards young stellar objects indicate that the radial distributions of the specific angular momentum j have a characteristic profile. In the inner region, typically R ≲ 100 au, the specific angular momenta distribute as j ∝ r1/2, indicating the existence of a rotationally supported disc. In the outer regions, R ≳ 5000 au, j increases as the radius increases, and the slope is steeper than unity. This behaviour is assumed to reflect the original angular momentum distributions in the maternal molecular clouds. In the intermediate region, 100 au ≲ R ≲ 5000 au, the j-distribution appears to be almost flat. While this is often interpreted to be a consequence of the conservation of the specific angular momentum, the interpretation actually is insufficient and requires a stronger condition that the initial distribution of j must be spatially uniform. However, this requirement seems to be unrealistic and inconsistent with observations. In this work, we propose a simple alternative explanation: the apparently flat j profile is produced by strong elongation owing to the large velocity gradient in the accreting flow, no matter what the initial j-distribution is. In order to show this, we provide a simple analytic model for the gravitational collapse of molecular clouds. We also propose a method to estimate the ages of protostars using only the observed rotation profile. We demonstrate the validity of this method in comparison with hydrodynamic simulations, and apply the model to the young stellar objects L1527 IRS, TMC-1A and B335.

  12. Psychopathological profile of patients with different forms of bruxism.

    Science.gov (United States)

    Bayar, Gurkan Rasit; Tutuncu, Recep; Acikel, Cengizhan

    2012-02-01

    The aim of the current study was to evaluate the prevalence of psychopathological symptoms in patients who self-reported different forms of bruxism by means of clinical and anamnestic diagnostic criteria. Eighty-five participants were divided into four groups as sleep bruxers (12), awake bruxers (24), sleep-awake bruxers (33), and non-bruxers (16). A self-report symptom inventory questionnaire (Symptom Checklist-90-Revised (SCL-90-R)) was filled out by all groups to determine their psychopathological symptoms. As regards mean psychopathological scores, patients with sleep-awake bruxism endorsed the highest scores. In addition, patients with awake bruxism showed higher scores than patients with sleep bruxism and non-bruxism in most SCL-90-R subscales. Kruskal-Wallis test revealed significant differences between groups in any of the SCL-90-R subscales, except for the psychoticism subscale. Mann-Whitney test followed by Bonferroni's test correction between non-bruxer and sleep-awake bruxer groups revealed significant differences in depression, anxiety, hostility, phobic anxiety, paranoid ideation, global severity index, positive symptom distress index, and positive symptom total in all SCL-90-R subscales. Statistical analysis of our study showed that differences between groups were significant in all SCL-90-R subscales except for the psychoticism subscale. Better distinction of bruxism forms may help to develop new treatment strategies for bruxism disorder.

  13. Cold spraying of aluminum bronze on profiled submillimeter cermet structures formed by laser cladding

    Science.gov (United States)

    Ryashin, N. S.; Malikov, A. G.; Shikalov, V. S.; Gulyaev, I. P.; Kuchumov, B. M.; Klinkov, S. V.; Kosarev, V. F.; Orishich, A. M.

    2017-10-01

    The paper presents results of the cold spraying of aluminum bronze coatings on substrates profiled with WC/Ni tracks obtained by laser cladding. Reinforcing cermet frames shaped as grids with varied mesh sizes were clad on stainless steel substrates using a CO2 laser machine "Siberia" (ITAM SB RAS, Russia). As a result, surfaces/substrates with heterogeneous shape, composition, and mechanical properties were obtained. Aluminum bronze coatings were deposited from 5lF-NS powder (Oerlikon Metco, Switzerland) on those substrates using cold spraying equipment (ITAM SB RAS). Data of profiling, microstructure diagnostics, EDS analysis, and mechanical tests of obtained composites is reported. Surface relief of the sprayed coatings dependence on substrate structure has been demonstrated.

  14. Simulative Winding of Roll Formed Profile in Carcass Production for Flexible Pipes

    DEFF Research Database (Denmark)

    Nielsen, Peter Søe; Ormstrup, Casper Alexander; Hartz, Benjamin Arnold Krekeler

    2015-01-01

    In carcass production for flexible pipe systems roll formed profiles are wound around a mandrel forming an interlocking, flexible structure able to withstand collapse from outside water pressure or mechanical crushing. Carcass is often produced in lengths of several kilometres, which implies...

  15. Experimental Studies of The Back-To-Back Connected Cold Formed Steel Profile Bolted Joints

    OpenAIRE

    Teofil F. Galăţanu; I. P. Ciongradi; M. Budescu; Octavian Roşca

    2009-01-01

    This paper presents the experimental test results of joints connecting the cold formed thin-walled steel profiles assembled in a pair, back-to-back cross section. The tests were carried on at the Faculty of Civil Engineering and Building Services from Iasi. In the first testing stage there were tested the joints of a frame structural model connected with high strength friction bolts. In the second stage, it was advocated the increase of the profile bearing capacity by introducing some supplem...

  16. Inform@ed space

    DEFF Research Database (Denmark)

    Bjerrum, Peter; Olsen, Kasper Nefer

    2001-01-01

    Inform@ed space Sensorial Perception And Computer Enchancement - bidrag til Nordisk Arkitekturforskningsforenings IT-konference, AAA april 2001.......Inform@ed space Sensorial Perception And Computer Enchancement - bidrag til Nordisk Arkitekturforskningsforenings IT-konference, AAA april 2001....

  17. Vertical density profile and internal bond strength of wet-formed particleboard bonded with cellulose nanofibrils

    Science.gov (United States)

    John F. Hunt; Weiqi Leng; Mehdi Tajvidi

    2017-01-01

    In this study, the effects of cellulose nanofibrils (CNFs) ratio, press program, particle size, and density on the vertical density profile (VDP) and internal bond (IB) strength of the wet-formed particleboard were investigated. Results revealed that the VDP was significantly influenced by the press program. Pressing using a constant pressure (CP) press program...

  18. Micro-PIC. A Simple Form of the Profile of Interaction in the Classroom.

    Science.gov (United States)

    Forbes, Joan

    The Profile of Interaction in the Classroom (PIC) is a feedback method of interaction analysis, based on the Flanders System, created for supervisors of pre-service and in-service teacher education. The Micro-PIC is an abbreviated simplified form for analysis of shorter periods of interaction, particularly in microteaching. The Micro-PIC…

  19. Development and Validation of a Short Form for the Multidimensional Work Ethic Profile

    Science.gov (United States)

    Meriac, John P.; Woehr, David J.; Gorman, C. Allen; Thomas, Amanda L. E.

    2013-01-01

    The multidimensional work ethic profile (MWEP) has become one of the most widely-used inventories for measuring the work ethic construct. However, its length has been a potential barrier to even more widespread use. We developed a short form of the MWEP, the MWEP-SF. A subset of items from the original measure was identified, using item response…

  20. Spurious reticulocyte profiles in dogs with large form babesiosis: a retrospective study.

    Science.gov (United States)

    Piane, Laetitia; Young, Karen M; Giraud, Lena; Bourges-Abella, Nathalie; Trumel, Catherine

    2016-12-01

    Erroneously high reticulocyte counts (pseudoreticulocytosis) have been reported in dogs with leukemia. Pseudoreticulocytosis and an abnormal reticulocyte profile were observed in a dog with large form babesiosis presented at our institution. The aims of this retrospective study were to determine if dogs with babesiosis and other dogs had abnormal reticulocyte profiles, and to correlate these profiles with the primary diagnosis. All canine CBCs obtained with the Sysmex XT-2000iV or Procyte DX were reviewed. Cases of large form babesiosis were identified and their reticulocyte dot plots were analyzed. Dogs with abnormal reticulocyte profiles but without microscopically apparent intraerythrocytic Babesia piroplasms were identified. The reticulocyte profiles and fluorescence ratios of dogs with and without babesiosis were compared. Twenty of 92 dogs with babesiosis had abnormal reticulocyte profiles, including 8 with a separation between the reticulocyte and mature RBC plots or a continuum of reticulocytes from the RBC plot but with a higher density of dots in the middle of the "comet tail" than in the left quarter of the dot plot. Thirteen of 6980 dogs without Babesia on the blood smear had abnormal reticulocyte profiles, including 3 with leukemia. The medium-fluorescence reticulocyte ratios tended to be higher in dogs with babesiosis and abnormal dot plots than in other dogs, whereas the high-fluorescence ratio was higher in one dog with leukemia. Abnormal reticulocyte dot plots and atypical reticulocyte fluorescence ratios may occur in dogs with babesiosis and alert clinical pathologists to consider this diagnosis. © 2016 American Society for Veterinary Clinical Pathology.

  1. Dissolution Profile of Mefenamic Acid Solid Dosage Forms in Two Compendial and Biorelevant (FaSSIF) Media.

    Science.gov (United States)

    Nurhikmah, Wilda; Sumirtapura, Yeyet Cahyati; Pamudji, Jessie Sofia

    2016-01-01

    Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID) that is widely used for the treatment of mild-to-moderate pain. Mefenamic acid belongs to the Biopharmaceutical Classification System (BCS) class II drug which has lower water solubility but high permeability. There are two different compendial methods available for dissolution tests of mefenamic acid solid dosage forms, i.e. methods of United States Pharmacopeia 37 (USP) and Pharmacopoeia of the People's Republic of China 2010 (PPRC). Indonesian Pharmacopeia V ed. (FI) adopted the USP method. On the other hand, many researches focused on the use of a 'biorelevant' medium to develop the dissolution test method. The aim of this research was to study the dissolution profile of mefenamic acid from its solid dosage forms (caplet and capsule) available in the Indonesian market with three different dissolution medium: USP, PPRC, and biorelevant fasted simulated small intestinal fluid (FaSSIF) media. The tested products consisted of the innovator's product (available only in caplet dosage form, FN caplet) and generic products (available as caplet and capsule). The dissolution test of the drug products in all dissolution media was performed in 900 mL of medium using apparatus II (paddle) at a temperature of 37°C and rotation speed of 75 rpm, except for the capsule product and for USP medium, both of which tests were done using apparatus I (basket) with rotation speed of 100 rpm. The solubility test of mefenamic acid was carried out in all media at temperature of 37°C. The result obtained from the solubility test showed that the the highest solubility of mefenamic acid was obtained in USP medium (approximately 2 mg/mL), followed by PPRC medium (about 0.5 mg/mL), and FaSSIF medium (approximately 0.06 mg/ml). In the dissolution test, percentage of drug dissolved in in the USP and PPRC media after 45 min for all products reached more than 75%, except for the PN caplet in USP medium which reached only about 44

  2. Developing a short form of Oral Health Impact Profile (OHIP) for dental aesthetics: OHIP-aesthetic.

    Science.gov (United States)

    Wong, Anthony H H; Cheung, C S; McGrath, Colman

    2007-02-01

    To develop and evaluate shortened forms of the Oral Health Impact Profile (OHIP) for discriminating dental aesthetics problems and evaluating dental aesthetic outcomes. Eighty-seven subjects self-completed the 49-item OHIP at baseline and 63 at follow up (8 weeks later), with the intervention of applying an array of tooth-whitening products. Expert-based approach and regression analysis (on baseline data) were undertaken to derive two subset questionnaires (OHIP-conceptual and OHIP-regression). Their discriminatory ability for dental aesthetics and their responsiveness to tooth whitening were compared with the original OHIP-49, Slade's OHIP-14 and a Chinese short-form version of OHIP. The measures developed were strongly associated with self-rating of dental aesthetics (P 0.05). The measures were also reliable (Cronbach's alpha 0.86) and comparable with the other OHIP forms. In terms of effect size, OHIP-conceptual was more effective in measuring changes than the one based on the regression analysis, the original OHIP-49, OHIP-14 and the Chinese version of the short-form OHIP. It also exhibited a less susceptibility to floor effects than other OHIP forms. A modified short form of the OHIP derived (OHIP-conceptual) was the most favorable in discriminating dental aesthetics, was reliable and most sensitive to the dental aesthetics intervention - tooth whitening.

  3. Review: Bernt Schnettler & Hubert Knoblauch (Eds. (2007. Powerpoint-Präsentationen. Neue Formen der gesellschaftlichen Kommunikation von Wissen [Powerpoint Presentations: New Forms of Social Communication of Knowledge

    Directory of Open Access Journals (Sweden)

    Thomas Hestermann

    2009-03-01

    Full Text Available The book "Powerpoint-Präsentationen. Neue Formen der gesellschaftlichen Kommunikation von Wissen" (Powerpoint Presentations: New Forms of Social Communication of Knowledge, edited by SCHNETTLER und KNOBLAUCH, is devoted to a previously underresearched subject: the features and effects of presentations supported by software, and in particular by Microsoft's "PowerPoint," The authors explain that, from sociological and linguistic viewpoints, presentations have a greater impact on content than the bare texts and pictures on the slides. The slides shown during a presentation gain in meaning when supported by a presenter who not only speaks but uses body language and various presentation techniques. Difficulties in communication can arise when organizations replace traditional reports with powerpoint slides. The book is considered in the context of current research and opinions on powerpoint. A critical look is taken at the claim that powerpoint per se is responsible for disasters such as the crash of the Columbia space shuttle. The decisive factor seems to be more a question of how competent users are in using presentation software and the associated communication techniques. URN: urn:nbn:de:0114-fqs0902135

  4. ED-XRF spectrometry-based comparative inorganic profile of leaf-derived in vitro calli and in vivo leaf samples of Phyllanthus amarus Schum. and Thonn.-a hepatoprotective herb

    Energy Technology Data Exchange (ETDEWEB)

    Nayak, P., E-mail: pranati_nayak_23@yahoo.co.i [Plant Tissue and Cell Culture Facility, Post-Graduate Department of Botany, Utkal University, Bhubaneswar 751004, Orissa (India); Plant Biotechnology Laboratory, Institute of Minerals and Materials Technology, (C.S.I.R., Govt. of India), Bhubaneswar 751013, Orissa (India); Behera, P.R., E-mail: priyaranjan2004@gmail.co [Plant Tissue and Cell Culture Facility, Post-Graduate Department of Botany, Utkal University, Bhubaneswar 751004, Orissa (India); Plant Biotechnology Laboratory, Institute of Minerals and Materials Technology, (C.S.I.R., Govt. of India), Bhubaneswar 751013, Orissa (India); Thirunavoukkarasu, M., E-mail: mtarasu@yahoo.co [Plant Biotechnology Laboratory, Institute of Minerals and Materials Technology, (C.S.I.R., Govt. of India), Bhubaneswar 751013, Orissa (India); Chand, P.K., E-mail: pkchanduubot@rediffmail.co [Plant Tissue and Cell Culture Facility, Post-Graduate Department of Botany, Utkal University, Bhubaneswar 751004, Orissa (India)

    2011-03-15

    The Energy Dispersive X-ray Fluorescence (ED-XRF) set-up incorporating a molybdenum secondary exciter was used for quantitative determination of major and minor elements in leaves of in vivo grown medicinal herb Phyllanthus amarus vis-a-vis its leaf-derived in vitro callus culture. The elements such as K, Ca, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Se, Rb, Sr and Pb were identified, quantified and compared between both the sources. Experimental results revealed that, compared to the naturally grown herb, in vitro leaf-derived callus cultures were more efficient in accumulating inorganic elements, especially trace elements, which are essential for growth and development and more importantly for prevention and cure of diseases. This investigation on a medicinal plant species is the first of its kind to have used the ED-XRF technique to demonstrate a comparative account of the elemental profile of in vitro callus cultures with their in vivo donor in order to explore the possibility of exploiting the former as a viable alternative and a renewable source of phytochemicals.

  5. CLASSIFICATION OF RESTRAINTS IN THE OPTIMIZATION PROBLEM OF A COLD-FORMED PROFILE

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    Agnieszka Łukowicz

    2015-11-01

    Full Text Available This work describes the restraints in the optimization problem. This is an important and complicated issue because it requires taking into account a vast range of information related to the design and production. In order to describe the relations of a specific optimization problem, it is essential to adopt appropriate criteria and to collect information on all kinds of restraints, i.e. boundary conditions. The following paper verifies the various restraints and defines three subsets: design assumptions, technological limitations and standard conditions. The provided classification was made with reference to the analysis of the construction applicability of the newly patented cold-formed profile.

  6. Experimental Studies of The Back-To-Back Connected Cold Formed Steel Profile Bolted Joints

    Directory of Open Access Journals (Sweden)

    Teofil F. Galăţanu

    2009-01-01

    Full Text Available This paper presents the experimental test results of joints connecting the cold formed thin-walled steel profiles assembled in a pair, back-to-back cross section. The tests were carried on at the Faculty of Civil Engineering and Building Services from Iasi. In the first testing stage there were tested the joints of a frame structural model connected with high strength friction bolts. In the second stage, it was advocated the increase of the profile bearing capacity by introducing some supplementary elements at the flanges; the maximum stresses were expected there and occurred. The specimen is built and modeled as a simply supported beam. In the midspan it is constructed the joint that focuses the research interest. There the load is applied as a concentrated force. The tests were carried on in the quasi-static regime in several load-unloading cycles; in the last stage the load was increased until the model collapsed. The strengthening of the flange has not increased significantly the model stiffness, but the bearing capacity was increased with 20?35% depending on the profile type.

  7. [Spinal form and function profile: reference values for clinical use in low back pain].

    Science.gov (United States)

    Schröder, J; Braumann, K M; Reer, R

    2014-09-01

    Functional diagnostic approaches are helpful in the treatment of low back pain (LBP) patients. Reference data of asymptomatic individuals might be helpful to understand individual case profiles of LBP patients, to derive movement therapy goals and issues and to improve quality management in therapy monitoring. Spinal form and mobility in the dorsal flexion (static and dynamic rasterstereography), as well as isometric peak forces (back extension/trunk flexion) were analyzed in a cross-sectional study of 103 pain-free volunteers (52 females, 51 males) aged 18-40 years. Reference data could be demonstrated based on percentiles (5-95 %). There were significant differences between males and females for strength values and spinal form parameters describing the lumbosacral transition (p < 0.001), but not for the strength extension/flexion ratio (Ex/Flex), lumbar mobility (dorsiflexion) or any other spine shape parameter. Despite the problem of a normal spinal alignment it is proposed to use reference data percentiles of asymptomatic persons to construct a musculoskeletal functional profile for individual LBP patients, which might emphasize the character of different LBP disorders and could be useful in screening, therapy planning and monitoring.

  8. Electrophoretic protein profiles of mid-sized copepod Calanoides patagoniensis steadily fed bloom-forming diatoms

    Directory of Open Access Journals (Sweden)

    Victor M Aguilera

    2015-09-01

    Full Text Available Recent field and experimental evidence collected in the southern upwelling region off Concepción (36°5'S, 73°3'W showed an abrupt reduction (<72 h in the egg production rates (EPR of copepods when they were fed steadily and solely with the local bloom-forming diatom Thalassiosira rotula. Because diatoms were biochemically similar to dinoflagellate Prorocentrum minimum, a diet which supported higher reproductive outcomes, the fecundity reduction observed in copepod females fed with the diatom may have obeyed to post-ingestive processes, giving rise to resources reallocation. This hypothesis was tested by comparing feeding (clearance and ingestion rates, reproduction (EPR and hatching success and the structure of protein profiles (i.e., number and intensity of electrophoretic bands of copepods (adults and eggs incubated during 96 h with the two food conditions. The structure of protein profiles included molecular sizes that were calculated from the relative mobility of protein standards against the logarithm of their molecular sizes. After assessing the experimental conditions, feeding decreased over time for those females fed with T. rotula, while reproduction was higher in females fed with P. minimum. Electrophoretic profiles resulted similar mostly at a banding region of 100 to 89-kDa, while they showed partial differences around the region of 56-kDa band, especially in those females fed and eggs produced with T. rotula. Due to reproductive volume was impacted while larvae viability, a physiological processes with specific and high nutritional requirements, was independent on food type; post-ingestive processes, such as expression of stress-related proteins deviating resources to metabolic processes others than reproduction, are discussed under framework of nutritional-toxic mechanisms mediating copepod-diatoms relationships in productive upwelling areas.

  9. PREFACE: EDS2010 Preface

    Science.gov (United States)

    Heggie, Malcolm I.

    2011-03-01

    The biennial international conference on Extended Defects in Semiconductors started in 1978 with a meeting in Hünfeld, Germany. Subsequent meetings rotated between Poland, France, Great Britain, Germany, Russia and Italy, culminating in EDS2004 in Chernogolovka, EDS2006 in Halle and EDS2008 in Poitiers. EDS2010 was held at the University of Sussex at Brighton, UK from September 19th to 24th. An extension of the tabulation of this history, which first appeared on the EDS2006 website, is given in the attached PDF. It is with sadness that we note one of the founders of the series, Prof. Dr Helmut Alexander, passed away on 3 December 2009 and we were proud to dedicate EDS2010 to his memory. It has become a tradition to make an award in his name, and this year it was made to Ivan Isacov for his poster "Electrical levels of dislocation networks in p- and n-type silicon". A short and warm celebration of Prof. Dr Alexander's life by his friends and colleagues, Prof. Drs Helmut Gottschalk, Eicke Weber and Wolfgang Schröter, is included in this volume. The conference was a forum for the state-of-the-art of investigation and modelling of extended defects in semiconductors. Scientists from universities, research institutes and industry made contributions to a deeper understanding of extended defects, their interaction with point defects and their role in the development of semiconductor technology. The remit of the conference included extended defects, nanostructures, nanoparticles, quantum dots and interfaces within semiconducting materials ranging from narrow to wide band gaps, including graphene-derived materials and diamond. Scientific interests range from defect geometry, electronic structure, dynamics, spectroscopy, microscopy, reactions and chemistry to introduction mechanisms, such as implantation and strained layers and the operation of devices such as integrated circuits, heterostructures, and solar cells. The organisers were confronted with a long period between

  10. Reaction profile in patch testing with allergens formed during vulcanization of rubber.

    Science.gov (United States)

    Hansson, Christer; Pontén, Ann; Svedman, Cecilia; Bergendorff, Ola

    2014-05-01

    Vulcanization of rubber changes its allergen pattern. To estimate the contact allergic reactivity profile of users of finished rubber products. Twenty-four patients with known contact allergy to rubber accelerators were patch tested with 21 compounds found in chemical analyses of vulcanized rubber products. No diphenylguanidine, p-phenylenediamine antioxidants or thioureas were included in the study. Thiuram monosulfides formed during vulcanization showed generally stronger test reactions than the corresponding thiuram disulfides. We also obtained more positive thiuram reactions to the monosulfides than to the disulfides. A positive reaction to a dithiocarbamate was accompanied by a positive reaction to the corresponding thiuram, except for 1 patient. The nitrogen substituents showed only minor differences between the methyl, ethyl and pentamethylene groups, but the butyl derivatives gave, in most cases, a negative response. Dialkylthiocarbamyl benzothiazole sulfides, formed between thiurams and mercaptobenzothiazoles during vulcanization, showed strong test reactions in almost all patients who were sensitive to dithiocarbamates, thiurams, or mercaptobenzothiazoles. We found thiuram monosulfides to be better markers of thiuram sensitivity than the corresponding disulfides or dithiocarbamates. Surprisingly, the dialkylthiocarbamyl benzothiazole sulfides were good markers of both thiuram and mercaptobenzothiazole sensitivity. This is an unexpected finding that needs to be confirmed in a larger study. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  11. Non-contact automatic measurement of free-form surface profiles on CNC machines

    Science.gov (United States)

    Fan, Kuang-Chao; Wen, Kuang-Pu

    1993-09-01

    This paper describes the work to develop a non-contact type automatic measurement system for any free-form surfaces on a CNC machine tool or a coordinate measuring machine (CMM) and its CAD/CAM integration. A laser probe made by Keyence Co. model LC-2220 was integrated into the CNC machine as the non-contact sensor. A measurement software has been developed for automatic surface tracing of any free-form profile. Data transfer to any commercially available CAD/CAM system for reverse engineering is also available via proper DXF file. Extensive calibration work has been carried out on the systematic accuracy of the laser probe with respect to the color material surface slope and edge detection of the workpiece by the use of a HP5528 laser interferometer system. Having employed the surface painting technique the shape error of the copied object relative to its master piece was found within 30 micrometers which is deemed adequate enough to the mold industry.

  12. Physical data of soil profiles formed on late Quaternary marine terraces near Santa Cruz, California

    Science.gov (United States)

    Munster, Jennie; Harden, Jennifer W.

    2002-01-01

    The marine terraces in and around Santa Cruz, California, represent a set of well-preserved terraces formed as a product of geology, sea level, and climate. A marine terrace begins as a wave cut platform. Eustatic sea level changes, seacliff erosion, and tectonic uplift work together to generate marine terraces. "When a wave-cut platform is raised (due to tectonic activity) above sea level and cliffed by wave action it becomes a marine terrace" (Bradley, 1957, p. 424). During glacial periods, eustatic sea level is estimated to have dropped by 150 meters (Fairbanks, 1989). Cliff retreat measured from aerial photographs between 1930 and 1980 vary from 0.0 to 0.2 m yr–1 (Best and Griggs, 1991). Estimates of uplift rates along the Santa Cruz coastline vary from 0.10 to 0.48 m kyr–1 (Bradley and Griggs, 1976; Weber and others, 1999). Uplift mechanisms include coseismic uplift associated both with a reverse component of slip on the steeply SW dipping Loma Prieta fault in the restraining bend of the San Andreas Fault and a small component of reverse slip on the steeply SE dipping San Gregorio fault (Anderson and Menking 1994). Previous work studying physical properties on these terraces include Pinney and others (in press) and Aniku (1986) and Bowman and Estrada (1980). Sedimentary deposits of the marine terraces are a mixture of terrestrial and marine sediments but generally consist of a sheet of marine deposits overlying the old platform and a wedge of nonmarine deposits banked against the old sea cliff (Bradley, 1957). Bedrock underlying the terraces in the Santa Cruz area is generally either Santa Margarita Sandstone or Santa Cruz Mudstone. The Santa Margarita Sandstone represents an upper Miocene, transgressive, tidally dominated marine-shelf deposit with crossbedded sets of sand and gravel and horizontally stratified and bioturbated invertebrate-fossils beds (Phillips, 1990). The siliceous Santa Cruz Mudstone, of late Miocene age, conformably overlies the Santa

  13. Size effects in winding roll formed profiles: A study of carcass production for flexible pipes in offshore industry

    DEFF Research Database (Denmark)

    Nielsen, Peter Søe; Nielsen, Morten Storgaard; Bay, Niels

    2013-01-01

    Carcass production of flexible offshore oil and gas pipes implies winding and interlocking of a roll formed stainless steel profile around a mandrel in a spiral shape. The location of the dividing point between the left and right half of the s-shaped profile in the finished carcass is very...... important as it directly influences carcass flexibility. The target location of the dividing point can be difficult to achieve since undesired degrees of freedom in the winding stage allows the profile to change geometry. The present work investigates this issue by performing production tests of a single...

  14. Empirical Profiling of Cold Hydrogen Plumes Formed from Venting Of LH2 Storage Vessels: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Buttner, William J [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Rivkin, Carl H [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Schmidt, Kara [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Hartmann, Kevin S [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Wright, Hannah [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Weidner, Eveline [Joint Research Centre, Petten, the Netherlands; Ciotti, Michael [H2 Fueling and CIP Markets Engineering

    2017-11-16

    Liquid hydrogen (LH2) storage is a viable approach to assuring sufficient hydrogen capacity at commercial fuelling stations. Presently, LH2 is produced at remote facilities and then transported to the end-use site by road vehicles (i.e., LH2 tanker trucks). Venting of hydrogen to depressurize the transport storage tank is a routine part of the LH2 delivery process. The behaviour of cold hydrogen plumes has not been well-characterized because empirical field data is essentially non-existent. The NFPA 2 Hydrogen Storage Safety Task Group, which consists of hydrogen producers, safety experts, and CFD modellers, has identified the lack of understanding of hydrogen dispersion during LH2 venting of storage vessel as a critical gap for establishing safety distances at LH2 facilities, especially commercial hydrogen fuelling stations. To address this need, the NREL sensor laboratory, in collaboration with the NFPA 2 Safety Task Group developed the Cold Hydrogen Plume Analyzer to empirically characterize the hydrogen plume formed during LH2 storage tank venting. A prototype Analyzer was developed and field-deployed at an actual LH2 venting operation with critical findings that included: - H2 being detected as much as 2 m lower than the release point, which is not predicted by existing models - A small and inconsistent correlation between oxygen depletion and the hydrogen concentration - A negligible to non-existent correlation between in-situ temperature and the hydrogen concentration The Analyzer is currently being upgraded for enhanced metrological capabilities including improved real-time spatial and temporal profiling of the plume and tracking of prevailing weather conditions. Additional deployments are planned to monitor plume behaviour under different wind, humidity, and temperatures. This data will be shared with the NFPA 2 Safety Task Group and ultimately will be used support theoretical models and code requirements prescribed in NFPA 2.

  15. Mesavage and Girard form class taper functions derived from profile equations

    Science.gov (United States)

    Thomas g. Matney; Emily B. Schultz

    2007-01-01

    The Mesavage and Girard (1946) average upper-log taper tables remain a favorite way of estimating tree bole volume because they only require the measurement of merchantable (useable) height to an indefinite top diameter limit. For the direct application of profile equations, height must be measured to a definite top diameter limit, and this makes the collection of data...

  16. Mathematical model of forming screw profiles of compressor machines and pumps

    Science.gov (United States)

    Panchuk, K. L.; Lyashkov, A. A.; Varepo, L. G.

    2017-10-01

    The article presents the results of mathematical modeling of screw surfaces shaping for compressor machines and pumps. The study is based on a method of curve movable trihedron. A mathematical model of a flat gearing - the basis for a screw formation - is proposed. The model is based on geometric interpretation of plane curve trihedron motions and known in a geometric theory of plane mechanisms of the Bobillier construction. A geometric scheme of this construction was expanded due to introduction of evolutes simulating instantaneous motions of curves trihedra in a construction scheme. As a result, the mathematical model was obtained, which is more complete in comparison with the known models of flat gearing, which makes it possible to perform synthesis and analysis of profiled screws geometry. It realizes both direct and inverse problems of screws profiling with simultaneous obtaining the curvature of the desired profiles in absent ones. The proposed model can be used as a basis of automated system development for mutually enveloping surfaces screws shaping for compressor machines and pumps.

  17. EDS becomes CERN Openlab contributor

    CERN Multimedia

    2007-01-01

    "EDS today announced that it has become an official contributor to CERN openlab. The purpose of the joint project between CERN and EDS is to carry out research and development in the field of monitoring, management and operaiton of grid services." (2/3 page)

  18. Rebooting the EdD

    Science.gov (United States)

    Wergin, Jon F.

    2011-01-01

    In this essay, Jon Wergin reminds readers of the philosophical and historical foundations of the doctor of education (EdD) degree. He argues that the EdD should be based, in large part, on John Dewey's progressive ideals of democratization and Paulo Freire's concepts of emancipatory education. Drawing on theories of reflective practice,…

  19. EDS becoms CERN Openlab contributor

    CERN Multimedia

    2007-01-01

    "EDS announced that it has become an official contributor to CERN openlab. The purpose of the joint project beteween CERN and EDS is to carry out research and development in the field of monitoring, management and operation of grid services." (1 page)

  20. Differential cytokine gene expression profiles in the three pathological forms of sheep paratuberculosis

    Science.gov (United States)

    Smeed, Jennifer A; Watkins, Craig A; Rhind, Susan M; Hopkins, John

    2007-01-01

    Background Johne's disease is a chronic inflammatory disease of the gut caused by infection with Mycobacterium avium subspecies paratuberculosis (MAP). Symptoms include wasting, diarrhoea, loss of condition and eventual death. Three forms of Johne's disease have been described in sheep – paucibacillary, multibacillary and asymptomatic. The paucibacillary form is characterized by an inflammatory, Th1-type immune response. The multibacillary form of the disease, which disseminates the infection, is characterized by macrophage infiltration mediated by a Th2-type immune response, and asymptomatic animals have no clinical symptoms or pathology but are infected with MAP. What determines these three forms of the disease is unknown. To further understand these differences, we used real-time RT-PCR to compare the expression of thirteen cytokine and cytokine-related genes in ileal tissue from sheep with the three forms of the disease. Results Three pathological forms of sheep paratuberculosis were defined on the basis of histopathology, cytochemistry (Zeihl-Neelsen) and IS900 PCR. Paucibacillary lesions have largely T cell and eosinophil infiltration and are ZN negative; multibacillary lesions have macrophage infiltration and large numbers of acid-fast bacteria. The pauci- and multibacillary forms are linked to the differential expression of IFNγ and IL-10 respectively. In addition the increased levels of the proinflammatory cytokines (IL-1β and TNFα), IL-8, IL-18 and TRAF-1 in both diseased forms is indicative of persistent inflammatory lesions. No changes were seen in IL-1α in any sheep ileum tissues. Asymptomatic animals are IS900+ with normal histology but have significantly decreased levels of IL-18 and increased levels TNFα. Conclusion We have quantified the expression levels of thirteen cytokine and cytokine related genes in three forms of ovine paratuberculosis using real-time PCR analyses and confirm that sheep pauci- and multibacillary disease are linked to

  1. Differential cytokine gene expression profiles in the three pathological forms of sheep paratuberculosis

    Directory of Open Access Journals (Sweden)

    Rhind Susan M

    2007-08-01

    Full Text Available Abstract Background Johne's disease is a chronic inflammatory disease of the gut caused by infection with Mycobacterium avium subspecies paratuberculosis (MAP. Symptoms include wasting, diarrhoea, loss of condition and eventual death. Three forms of Johne's disease have been described in sheep – paucibacillary, multibacillary and asymptomatic. The paucibacillary form is characterized by an inflammatory, Th1-type immune response. The multibacillary form of the disease, which disseminates the infection, is characterized by macrophage infiltration mediated by a Th2-type immune response, and asymptomatic animals have no clinical symptoms or pathology but are infected with MAP. What determines these three forms of the disease is unknown. To further understand these differences, we used real-time RT-PCR to compare the expression of thirteen cytokine and cytokine-related genes in ileal tissue from sheep with the three forms of the disease. Results Three pathological forms of sheep paratuberculosis were defined on the basis of histopathology, cytochemistry (Zeihl-Neelsen and IS900 PCR. Paucibacillary lesions have largely T cell and eosinophil infiltration and are ZN negative; multibacillary lesions have macrophage infiltration and large numbers of acid-fast bacteria. The pauci- and multibacillary forms are linked to the differential expression of IFNγ and IL-10 respectively. In addition the increased levels of the proinflammatory cytokines (IL-1β and TNFα, IL-8, IL-18 and TRAF-1 in both diseased forms is indicative of persistent inflammatory lesions. No changes were seen in IL-1α in any sheep ileum tissues. Asymptomatic animals are IS900+ with normal histology but have significantly decreased levels of IL-18 and increased levels TNFα. Conclusion We have quantified the expression levels of thirteen cytokine and cytokine related genes in three forms of ovine paratuberculosis using real-time PCR analyses and confirm that sheep pauci- and

  2. Biofilm-forming ability profiling of Staphylococcus aureus and Staphylococcus epidermidis mastitis isolates

    DEFF Research Database (Denmark)

    Oliveira, M; Bexiga, R; Nunes, S F

    2006-01-01

    Biofilm-forming ability has been increasingly recognized as an important virulence factor in Staphylococci, facilitating their persistence in the host, evading its defences and allowing bacterial survival at high antimicrobial concentrations. Staphylococcus aureus remains a major pathogen...... of chronic mastitis, but in the last years Staphylococcus epidermidis has emerged as a relevant mastitis pathogen. The present work aimed at the evaluation of the biofilm-forming ability of Staphylococci field isolates from bovine subclinical mastitis and at the development of a fluorescent in situ...

  3. Seismic Behaviour of an Experimental Model Made of Thin-Walled Cold Formed Steel Profiles - Hardell Structures

    Directory of Open Access Journals (Sweden)

    Ionuţ-Ovidiu Toma

    2009-01-01

    Full Text Available The experimental results of the shaking table test of a Hardell structure made of thin-walled cold formed steel profiles are presented. The structure has the in-plane dimensions of 4x4 m and a height of 6 m, being classified as a P+1E type of structure. The dynamic characteristics of the structure were determined during the first stage of the experiment. Afterwards, the structure was subjected to different types of dynamic loadings such as sine-sweep functions and to seismic actions simulating the El Centro and Vrancea earthquakes. The damages induced by the seismic excitations consisted of local buckling of the steel profiles and breaking of two anchorage bolts holding the structure to the shaking table. Based on the experimental results it can be concluded that the structure can safely withstand seismic loads up to certain intensity, provided that some requirements are met.

  4. Canadian EdGEO National Workshop Program

    Science.gov (United States)

    Clinton, L. A.; Haidl, F. M.; Hymers, L. A.; van der Flier-Keller, E.

    2009-05-01

    -five teachers. Workshops have been presented at teachers' conferences, province-wide professional development days, industry events, and independently. Participants consistently rate EdGEO workshops as excellent and outstanding. Responses on the evaluation forms suggest that teachers value the hands-on aspect of the workshops, the strong connection to the curriculum, the classroom resources provided, the field components, the collaborations forged between teachers and geoscientists, and the knowledge gained. Comments also continually make reference to the talented experts who enthusiastically commit to sharing their expertise in geoscience. The ability of EdGEO to advance its vital mission relies on the generous support of scientific associations, corporations, foundations and individuals. With increased funding, EdGEO's future will see the expansion of partnerships with Faculties of Education across Canada. These faculties offer an opportunity to reach out to aspiring teachers before they enter the classroom. Future plans include the compilation of EdGEO lesson plans from coast to coast. These valuable resources would connect to provincial curriculum, provide an opportunity to wedge Earth science into other science subjects, and serve as the basis for developing a series of standardized workshops to be implemented across the nation.

  5. Ed.itorio.1

    African Journals Online (AJOL)

    Thanks to i:he inspiration. dedication and tenacity of some of its members, the Ethiopian Association ol. Engineers and Architects finally came around to hold its First National Conference in Addis Ababa. On the afternoon of June 23. 1971 the conference was form- ally opened by H.E. Lij Endalkatchew Ma~o~en,. Minister of ...

  6. The short form endometriosis health profile (EHP-5: translation and validation study of the Iranian version

    Directory of Open Access Journals (Sweden)

    Goshtasebi Azita

    2011-07-01

    Full Text Available Abstract Background Endometriosis Health Profile (EHP-5 is a valid instrument to measure health-related quality of life in endometriosis. This study was conducted to culturally adapt and validate the EHP-5 in Iran. Methods Using a standard "forward-backward' translation procedure, the English language version of the questionnaire was translated into Persian (Iranian language. Then a sample of 199 women aged 18-50 years completed the questionnaire. To test reliability the internal consistency was assessed by Cronbach's alpha coefficient. Validity was evaluated using known groups comparison. Results The mean age of respondents was 31.4 (SD = 5.4 years. Reliability analysis showed satisfactory result (Cronbach's alpha coefficient = 0.71. The questionnaire discriminated well between sub-groups of women differing in infertility and premenstrual syndrome (PMS in the expected direction. Conclusion This preliminary validation study of the Iranian version of the EHP-5 proved that it is an acceptable, reliable and valid measure of quality of life in endometriosis patients.

  7. TechEdSat Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The overall goal of the Technical Education Satellite (TechEdSat) is to employ a small spacecraft to evaluate, demonstrate, and validate two new technologies for...

  8. Role of roasting conditions in the profile of volatile flavor chemicals formed from coffee beans.

    Science.gov (United States)

    Moon, Joon-Kwan; Shibamoto, Takayuki

    2009-07-08

    The volatile chemicals in dichloromethane extracts from green coffee beans, roasted at 230 degrees C for 12 min (light), at 240 degrees C for 14 min (medium), at 250 degrees C for 17 min (city), or at 250 degrees C for 21 min (French), were analyzed by gas chromatography and gas chromatography-mass spectrometry. Among the 52 volatile compounds identified, the major compounds were 5-hydroxymethylfurfural, furfuryl alcohol, and 6-methyl-3,5-dihydroxy-4H-pyran-4-one in light-roasted beans; furfuryl alcohol, 5-hydroxymethylfurfural, and gamma-butyrolactone in medium-roasted beans; furfuryl alcohol, gamma-butyrolactone, and 2-acetylpyrrole in city-raosted beans; and gamma-butyrolactone, furfuryl alcohol, and catechol in French-roasted beans. Furfural derivatives and furanones were yielded in relatively high concentrations under mild roasting conditions and then reduced at higher roasting intensities. More pyridines and pyrroles were formed by high roasting intensities than by mild roasting intensities. Chlorogenic acid degradation products, phenols, and a lactone were produced more by high roasting intensities than by low roasting intensities. The results of the present study suggest that controlling the roasting conditions according to the formation of particular chemicals can prepare a roasted coffee with preferable flavor.

  9. Surface characteristics of the iron-oxyhydroxide layer formed during brick coatings by ESEM/EDS, {sup 23}Na and {sup 1}H MAS NMR, and ToF-SIMS

    Energy Technology Data Exchange (ETDEWEB)

    Allahdin, O. [Chaire Unesco « Sur la gestion de l' eau », Laboratoire Hydrosciences Lavoisier, Université de Bangui, Faculté des Sciences, B.P. 908 (Central African Republic); Wartel, M. [Université Lille1, Laboratoire LASIR (UMR CNRS 8516), Equipe Physico-chimie de l' Environnement, Bât. C8, 2" è" m" e étage, 59655 Villeneuve d' Ascq cedex (France); Mabingui, J. [Chaire Unesco « Sur la gestion de l' eau », Laboratoire Hydrosciences Lavoisier, Université de Bangui, Faculté des Sciences, B.P. 908 (Central African Republic); Revel, B. [Université Lille1, Service RMN, Bât. C4, 59655 Villeneuve d' Ascq cedex (France); Nuns, N. [Université Lille1, Institut Chevreul, 59655 Villeneuve d' Ascq cedex (France); Boughriet, A., E-mail: abdel.boughriet@univ-lille1.fr [Université Lille1, Laboratoire LASIR (UMR CNRS 8516), Equipe Physico-chimie de l' Environnement, Bât. C8, 2" è" m" e étage, 59655 Villeneuve d' Ascq cedex (France)

    2015-09-01

    Brick made locally by craftsmen in Bangui (Central African Republic) was modified first by HCl activation and second by iron-oxyhydroxide impregnation through the precipitation of ferric ions by NaOH at various fixed pH values (ranging from 3 to 13). The elemental analyses of synthesized compounds were performed using ICP-AES, and their surface chemistry/properties were investigated by environmental scanning electron microscopy (ESEM/EDS), {sup 1}H and {sup 23}Na MAS NMR spectroscopy, and time-of-flight secondary ion mass spectrometry (ToF-SIMS). The evidence of different {sup 23}Na chemical environments and the coexistence of Si and Al bound to ferrihydrite were made. The surface properties of this material which was found to be dependent upon synthesis pH, contributed to enhance metal uptake from water. - Highlights: • HCl-activated brick was coated at different Fe(III)-precipitation pH. • Surface properties were determined by ESEM, NMR and ToF-SIMS. • Al- and Si-bearing ferrihydrite and different Na environments were detected. • The pH used for modified-brick synthesis influenced metal uptake from water.

  10. Transcriptional Profiling Reveals a Common Metabolic Program in High-Risk Human Neuroblastoma and Mouse Neuroblastoma Sphere-Forming Cells

    Directory of Open Access Journals (Sweden)

    Mengling Liu

    2016-10-01

    Full Text Available High-risk neuroblastoma remains one of the deadliest childhood cancers. Identification of metabolic pathways that drive or maintain high-risk neuroblastoma may open new avenues of therapeutic interventions. Here, we report the isolation and propagation of neuroblastoma sphere-forming cells with self-renewal and differentiation potential from tumors of the TH-MYCN mouse, an animal model of high-risk neuroblastoma with MYCN amplification. Transcriptional profiling reveals that mouse neuroblastoma sphere-forming cells acquire a metabolic program characterized by transcriptional activation of the cholesterol and serine-glycine synthesis pathways, primarily as a result of increased expression of sterol regulatory element binding factors and Atf4, respectively. This metabolic reprogramming is recapitulated in high-risk human neuroblastomas and is prognostic for poor clinical outcome. Genetic and pharmacological inhibition of the metabolic program markedly decreases the growth and tumorigenicity of both mouse neuroblastoma sphere-forming cells and human neuroblastoma cell lines. These findings suggest a therapeutic strategy for targeting the metabolic program of high-risk neuroblastoma.

  11. Inside the Sex Ed Studio: An Interview with Peggy Brick

    Science.gov (United States)

    Taverner, William J.

    2008-01-01

    "Inside the Sex Ed Studio" profiles leaders in the field of sexuality education. Peggy Brick, former director of Planned Parenthood of Greater Northern New Jersey's Center for Family Life Education (CFLE) and author of numerous sexuality education resources used worldwide, is the subject of this interview. Ms. Brick was interviewed by…

  12. Transcriptional Profiling of Coxiella burnetii Reveals Extensive Cell Wall Remodeling in the Small Cell Variant Developmental Form

    Science.gov (United States)

    Sandoz, Kelsi M.; Popham, David L.; Beare, Paul A.; Sturdevant, Daniel E.; Hansen, Bryan; Nair, Vinod; Heinzen, Robert A.

    2016-01-01

    A hallmark of Coxiella burnetii, the bacterial cause of human Q fever, is a biphasic developmental cycle that generates biologically, ultrastructurally, and compositionally distinct large cell variant (LCV) and small cell variant (SCV) forms. LCVs are replicating, exponential phase forms while SCVs are non-replicating, stationary phase forms. The SCV has several properties, such as a condensed nucleoid and an unusual cell envelope, suspected of conferring enhanced environmental stability. To identify genetic determinants of the LCV to SCV transition, we profiled the C. burnetii transcriptome at 3 (early LCV), 5 (late LCV), 7 (intermediate forms), 14 (early SCV), and 21 days (late SCV) post-infection of Vero epithelial cells. Relative to early LCV, genes downregulated in the SCV were primarily involved in intermediary metabolism. Upregulated SCV genes included those involved in oxidative stress responses, arginine acquisition, and cell wall remodeling. A striking transcriptional signature of the SCV was induction (>7-fold) of five genes encoding predicted L,D transpeptidases that catalyze nonclassical 3–3 peptide cross-links in peptidoglycan (PG), a modification that can influence several biological traits in bacteria. Accordingly, of cross-links identified, muropeptide analysis showed PG of SCV with 46% 3–3 cross-links as opposed to 16% 3–3 cross-links for LCV. Moreover, electron microscopy revealed SCV with an unusually dense cell wall/outer membrane complex as compared to LCV with its clearly distinguishable periplasm and inner and outer membranes. Collectively, these results indicate the SCV produces a unique transcriptome with a major component directed towards remodeling a PG layer that likely contributes to Coxiella’s environmental resistance. PMID:26909555

  13. Exploring issues of personality measurement and structure through the development of a short form of the Eysenck Personality Profiler .

    Science.gov (United States)

    Petrides, K V; Jackson, Chris J; Furnham, Adrian; Levine, Stephen Z

    2003-12-01

    In this article, we develop a revised short form of the original Eysenck Personality Profiler (EPP; H. J. Eysenck & Wilson, 1991). In addition, we address topics of broad theoretical importance such as the recurrent empirical finding of correlations between conceptually orthogonal personality dimensions and the possibility that gender differences in these dimensions are partly spurious. In Study 1 (N = 227), we demonstrate that the existing short form of the EPP (EPP-SF; H. J. Eysenck, Wilson, & Jackson, 1996) provides a poor fit to the data and we develop a revised well-fitting version. In Study 2, we retest this version on an independent new sample (N = 3,374) where it is again found to fit the data well. We show that most of the structural and measurement parameters of the revised EPP-SF are invariant across genders. Structured means analysis indicated a significant gender difference in Psychoticism, with men scoring higher than women, but no differences in Extraversion or Neuroticism. Our discussion focuses on issues concerning personality measurement and structure, including an examination of the role of confirmatory factor analysis in personality research.

  14. Democrazia ed élites

    Directory of Open Access Journals (Sweden)

    N. BOBBIO

    2014-07-01

    Full Text Available L’articolo si propone di mostrare che la teoria della classe politica, formulata ed elaborata da scrittori conservatori con precisi intenti di polemica antidemocratica, è stata utilizzata anche da scrittori decoratici; in secondo luogo di confermare la tesi cara a Pareto, secondo cui altro è il valore scientifico di una teoria politica, altro il suo uso ideologico

  15. Mitigating Higher Ed Cyber Attacks

    Science.gov (United States)

    Rogers, Gary; Ashford, Tina

    2015-01-01

    In this presentation we will discuss the many and varied cyber attacks that have recently occurred in the higher ed community. We will discuss the perpetrators, the victims, the impact and how these institutions have evolved to meet this threat. Mitigation techniques and defense strategies will be covered as will a discussion of effective security…

  16. 35 years of EDS software.

    Science.gov (United States)

    Schamber, Frederick H

    2009-12-01

    The computerized multichannel analyzer running software specifically designed for X-ray analysis appeared very early in the commercialization of the energy dispersive X-ray spectrometer (EDS) and, like the solid-state X-ray detector itself, was built on a technology foundation originally developed for nuclear spectroscopy. However, software techniques employed for gamma-ray spectra could not accommodate the continuum component of EDS spectra, and a new approach was required. Least-squares fitting with "top-hat" filtered spectra proved to be an effective solution that is still widely used today. Though modern computer technology has subsequently contributed greatly to the speed and convenience of present-day EDS software, it seems that the achievable accuracy and precision of spectrum analysis has not fundamentally improved, and most of the early challenges are still quite relevant, although they may appear in new guises. The availability of the high speed silicon drift detector, however, may provide both the incentive and the data precision to drive future advances. This article traces the formative years of EDS software from the personalized perspective of a participant. Factors that shaped the development of the industry are identified, and future directions are speculated.

  17. Water in star-forming regions with Herschel (WISH) : IV. A survey of low-J H2O line profiles toward high-mass protostars

    NARCIS (Netherlands)

    van der Tak, F. F. S.; Chavarria, L.; Herpin, F.; Wyrowski, F.; Walmsley, C. M.; van Dishoeck, E. F.; Benz, A. O.; Bergin, E. A.; Caselli, P.; Hogerheijde, M. R.; Johnstone, D.; Kristensen, L. E.; Liseau, R.; Nisini, B.; Tafalla, M.

    Context. Water is a key constituent of star-forming matter, but the origin of its line emission and absorption during high-mass star formation is not well understood. Aims. We study the velocity profiles of low-excitation H2O lines toward 19 high-mass star-forming regions and search for trends with

  18. Ed Watson 1940-2006

    CERN Document Server

    2006-01-01

    Ed Watson arrived at CERN in March 1973 to work on digital electronics and CAMAC systems under Bob Dobinson, after many years at Rolls Royce in Scotland. He joined the European Muon Collaboration in 1976, where he played a major role in the design, deployment and running of its data acquisition system (DAQ) with David Botterill, Bob Dobinson, and Vicky White. The CAMAC-ROMULUS system was by far the largest and most advanced of its time, and it became a defining standard for DAQ systems for years to come. Ed was deeply involved in the detailed planning of the control rooms and the experiment cabling, as well as sharing the responsibility for the CAMAC readout system. He had a real talent for trouble shooting and played a vital part in supporting the experiment throughout its lifetime. He offered great moral support to the younger members of the collaboration and helped them a great deal with their work. The EMC had a wonderful social life to which Ed was a major contributor - who can forget its barbecues?  In...

  19. Ed Watson - 1940-2006

    CERN Multimedia

    2006-01-01

    Ed Watson passed away suddenly on 1 August in Geneva, he was 66. He leaves his wife and two children. Ed Watson arrived at CERN in March 1973 to work on digital electronics and CAMAC systems under Bob Dobinson, after many years at Rolls Royce in Scotland. He joined the European Muon Collaboration in 1976, where he played a major role in the design, deployment and running of its data acquisition system (DAQ) with David Botterill, Bob Dobinson, and Vicky White. The CAMAC-ROMULUS system was by far the largest and most advanced of its time, and it became a defining standard for DAQ systems for years to come. Ed was deeply involved in the detailed planning of the control rooms and the experiment cabling, as well as sharing the responsibility for the CAMAC readout system. He had a real talent for trouble shooting and played a vital part in supporting the experiment throughout its lifetime. He offered great moral support to the younger members of the collaboration and helped them a great deal with their work. The...

  20. Prediction of in-vivo pharmacokinetic profile for immediate and modified release oral dosage forms of furosemide using an in-vitro-in-silico-in-vivo approach.

    Science.gov (United States)

    Otsuka, Keiichi; Wagner, Christian; Selen, Arzu; Dressman, Jennifer

    2015-05-01

    To develop a physiologically based pharmacokinetic (PBPK) model for furosemide immediate release (IR) tablets and modified release (MR) capsules by coupling biorelevant dissolution testing results with pharmacokinetic (PK) and physiologic parameters, and to investigate the key factors influencing furosemide absorption using simulation approaches and the PBPK model. Using solubility, dissolution kinetics, gastrointestinal (GI) parameters and disposition parameters, a PBPK model for furosemide was developed with STELLA software. Solubility and dissolution profiles for both formulations were evaluated in biorelevant and compendial media. The simulated plasma profiles were compared with in-vivo profiles using point estimates of area under plasma concentration-time curve, maximal concentration after the dose and time to maximal concentration after the dose. Simulated plasma profiles of both furosemide IR tablets and MR capsules were similar to the observed in-vivo profile in terms of PK parameters. Sensitivity analysis of the IR tablet model indicated that both the gastric emptying and absorption rate have an influence on the plasma profile. For the MR capsules, the sensitivity analysis suggested that the release rate in the small intestine, gastric emptying and the absorption rate all have an influence on the plasma profile. A predictive model to describe both IR and MR dosage forms containing furosemide was attained. Because sensitivity analysis of the model is able to identify key factors influencing the plasma profile, this in-vitro-in-silico-in-vivo approach could be a useful tool for facilitating formulation development of drug products. © 2015 Royal Pharmaceutical Society.

  1. TrED: the Trichophyton rubrum Expression Database

    Directory of Open Access Journals (Sweden)

    Liu Tao

    2007-07-01

    Full Text Available Abstract Background Trichophyton rubrum is the most common dermatophyte species and the most frequent cause of fungal skin infections in humans worldwide. It's a major concern because feet and nail infections caused by this organism is extremely difficult to cure. A large set of expression data including expressed sequence tags (ESTs and transcriptional profiles of this important fungal pathogen are now available. Careful analysis of these data can give valuable information about potential virulence factors, antigens and novel metabolic pathways. We intend to create an integrated database TrED to facilitate the study of dermatophytes, and enhance the development of effective diagnostic and treatment strategies. Description All publicly available ESTs and expression profiles of T. rubrum during conidial germination in time-course experiments and challenged with antifungal agents are deposited in the database. In addition, comparative genomics hybridization results of 22 dermatophytic fungi strains from three genera, Trichophyton, Microsporum and Epidermophyton, are also included. ESTs are clustered and assembled to elongate the sequence length and abate redundancy. TrED provides functional analysis based on GenBank, Pfam, and KOG databases, along with KEGG pathway and GO vocabulary. It is integrated with a suite of custom web-based tools that facilitate querying and retrieving various EST properties, visualization and comparison of transcriptional profiles, and sequence-similarity searching by BLAST. Conclusion TrED is built upon a relational database, with a web interface offering analytic functions, to provide integrated access to various expression data of T. rubrum and comparative results of dermatophytes. It is devoted to be a comprehensive resource and platform to assist functional genomic studies in dermatophytes. TrED is available from URL: http://www.mgc.ac.cn/TrED/.

  2. 78 FR 55684 - ConnectED Workshop

    Science.gov (United States)

    2013-09-11

    ... National Telecommunications and Information Administration ConnectED Workshop AGENCY: National... in the United States to next- generation broadband. This Notice announces that the ConnectED Workshop... ConnectED Workshop will discuss the growing bandwidth needs of K-12 schools as more schools use mobile...

  3. AdvancED Flex 4

    CERN Document Server

    Tiwari, Shashank; Schulze, Charlie

    2010-01-01

    AdvancED Flex 4 makes advanced Flex 4 concepts and techniques easy. Ajax, RIA, Web 2.0, mashups, mobile applications, the most sophisticated web tools, and the coolest interactive web applications are all covered with practical, visually oriented recipes. * Completely updated for the new tools in Flex 4* Demonstrates how to use Flex 4 to create robust and scalable enterprise-grade Rich Internet Applications.* Teaches you to build high-performance web applications with interactivity that really engages your users.* What you'll learn Practiced beginners and intermediate users of Flex, especially

  4. SJS0504Pg000ED

    African Journals Online (AJOL)

    Enrique

    non-contrast spiral CT scan. Routine investigations in the book in terms of the metabol- ic evaluation of patients with a first episode of uncomplicated urolithiasis include a 24-hour urine biochemical profile irre- spective of stone composition. This is usually reserved for patients with recurrent urolithiasis of a high risk profile in.

  5. SMRT has tissue-specific isoform profiles that include a form containing one CoRNR box.

    Science.gov (United States)

    Short, Stephen; Malartre, Marianne; Sharpe, Colin

    2005-09-02

    SMRT acts as a corepressor for a range of transcription factors. The amino-terminal part of the protein includes domains that mainly mediate transcriptional repression whilst the carboxy-terminal part includes domains that interact with nuclear receptors using up to three motifs called CoRNR boxes. The region of the SMRT primary transcript encoding the interaction domains is subject to alternative splicing that varies the inclusion of the third CoRNR box. The profile in mice includes an abundant, novel SMRT isoform that possesses just one CoRNR box. Mouse tissues therefore express SMRT isoforms containing one, two or three CoRNR boxes. In frogs, the SMRT isoform profile is tissue-specific. The mouse also shows distinct profiles generated by differential expression levels of the SMRT transcript isoforms. The formation of multiple SMRT isoforms and their tissue-specific regulation indicates a mechanism, whereby cells can define the repertoire of transcription factors regulated by SMRT.

  6. Determination and estimation of pharmacokinetic profile of caffeine in form of extract of green tea leaves and its analogy with synthetic form.

    Science.gov (United States)

    Shanmugasundaram, Sangeetha; Manjunatha, N; Vijayan, R; Khatwal, R B; Samanta, M K

    2011-11-01

    The aim of the study was to formulate and investigate the pharmacokinetic parameters for the tablets of herbal extract of caffeine with comparison to synthetic formulation. The tablets of the aqueous herbal extract of leaves of Camellia sinensis and synthetic caffeine were formulated by wet granulation technique. The HPLC and HPTLC were applied as analytical tools for estimation of caffeine. The batches of formulation (B1 to B7) were subjected for various pre and post-formulation studies. The pharmacokinetic of the batch B5 was assessed in rabbits, and the results were compared to synthetic batch B7. With the suitable pre and post-formulation results, the B5 showed in vitro release of 90.54% of caffeine at the end of 60 min. The release followed first order kinetics and the plot of Higuchi and Peppas confirms anomalous diffusion as the basic mechanism behind the release. B5 revealed non-significant mean C(max), t(1/2), and AUC of 1.88 μg/ml, 5.52 h and 9.67 μg.h/ml respectively compared to B7. The study highlights; no significant difference in the pharmacological effect of caffeine when administered in the form of extract. The administration of herbal extract can further provide the other health benefits lacked by synthetic caffeine.

  7. UVI colour gradients of 0.4 star-forming main-sequence galaxies in CANDELS: dust extinction and star formation profiles

    Science.gov (United States)

    Wang, Weichen; Faber, S. M.; Liu, F. S.; Guo, Yicheng; Pacifici, Camilla; Koo, David C.; Kassin, Susan A.; Mao, Shude; Fang, Jerome J.; Chen, Zhu; Koekemoer, Anton M.; Kocevski, Dale D.; Ashby, M. L. N.

    2017-08-01

    This paper uses radial colour profiles to infer the distributions of dust, gas and star formation in z = 0.4-1.4 star-forming main-sequence galaxies. We start with the standard UVJ-based method to estimate dust extinction and specific star formation rate (sSFR). By replacing J with I band, a new calibration method suitable for use with ACS+WFC3 data is created (I.e. UVI diagram). Using a multi-wavelength multi-aperture photometry catalogue based on CANDELS (Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey), UVI colour profiles of 1328 galaxies are stacked in stellar mass and redshift bins. The resulting colour gradients, covering a radial range of 0.2-2.0 effective radii, increase strongly with galaxy mass and with global AV. Colour gradient directions are nearly parallel to the Calzetti extinction vector, indicating that dust plays a more important role than stellar population variations. With our calibration, the resulting AV profiles fall much more slowly than stellar mass profiles over the measured radial range. sSFR gradients are nearly flat without central quenching signatures, except for M⋆ > 1010.5 M⊙, where central declines of 20-25 per cent are observed. Both sets of profiles agree well with previous radial sSFR and (continuum) AV measurements. They are also consistent with the sSFR profiles and, if assuming a radially constant gas-to-dust ratio, gas profiles in recent hydrodynamic models. We finally discuss the striking findings that SFR scales with stellar mass density in the inner parts of galaxies, and that dust content is high in the outer parts despite low stellar mass surface densities there.

  8. Pharmacokinetic profile of two different pharmaceutical forms of theophylline (a slow release tablet and a syrup after multiple dose administration to healthy human volunteers

    Directory of Open Access Journals (Sweden)

    Marcelo Nicolás Muscará

    1993-03-01

    Full Text Available Due to the narrow therapeutic range of theophyline, plasma concentrations of this drug are monitored in patients undergoing chronic therapy. Slow-release preparations avoid the fluctuations in plasma levels and improve patient compliance. In this study, we have compared the pharmacokinetic profiles of a theophylline slow-release tablet and a syrup form, when administered in multiple doses to healthy adult volunteers. The classification based upon releasing patterns is confirmed.

  9. Forming disc galaxies in major mergers - III. The effect of angular momentum on the radial density profiles of disc galaxies

    Science.gov (United States)

    Peschken, N.; Athanassoula, E.; Rodionov, S. A.

    2017-06-01

    We study the effect of angular momentum on the surface density profiles of disc galaxies, using high-resolution simulations of major mergers whose remnants have downbending radial density profiles (type II). As described in the previous papers of this series, in this scenario, most of the disc mass is acquired after the collision via accretion from a hot gaseous halo. We find that the inner and outer disc scalelengths, as well as the break radius, correlate with the total angular momentum of the initial merging system, and are larger for high-angular momentum systems. We follow the angular momentum redistribution in our simulated galaxies, and find that like the mass, the disc angular momentum is acquired via accretion, I.e. to the detriment of the gaseous halo. Furthermore, high-angular momentum systems give more angular momentum to their discs, which directly affects their radial density profile. Adding simulations of isolated galaxies to our sample, we find that the correlations are valid also for disc galaxies evolved in isolation. We show that the outer part of the disc at the end of the simulation is populated mainly by inside-out stellar migration, and that in galaxies with higher angular momentum, stars travel radially further out. This, however, does not mean that outer disc stars (in type II discs) were mostly born in the inner disc. Indeed, generally the break radius increases over time, and not taking this into account leads to overestimating the number of stars born in the inner disc.

  10. A microarray-based method for the parallel analysis of genotypes and expression profiles of wood-forming tissues in Eucalyptus grandis

    Directory of Open Access Journals (Sweden)

    Lezar Sabine

    2009-05-01

    Full Text Available Abstract Background Fast-growing Eucalyptus grandis trees are one of the most efficient producers of wood in South Africa. The most serious problem affecting the quality and yield of solid wood products is the occurrence of end splitting in logs. Selection of E. grandis planting stock that exhibit preferred wood qualities is thus a priority of the South African forestry industry. We used microarray-based DNA-amplified fragment length polymorphism (AFLP analysis in combination with expression profiling to develop fingerprints and profile gene expression of wood-forming tissue of seven different E. grandis trees. Results A 1578-probe cDNA microarray was constructed by arraying 768 cDNA-AFLP clones and 810 cDNA library clones from seven individual E. grandis trees onto silanised slides. The results revealed that 32% of the spotted fragments showed distinct expression patterns (with a fold change of at least 1.4 or -1.4 and a p value of 0.01 could be grouped into clusters representing co-expressed genes. Evaluation of the binary distribution of cDNA-AFLP fragments on the array showed that the individual genotypes could be discriminated. Conclusion A simple, yet general method was developed for genotyping and expression profiling of wood-forming tissue of E. grandis trees differing in their splitting characteristics and in their lignin contents. Evaluation of gene expression profiles and the binary distribution of cDNA-AFLP fragments on the chip suggest that the prototype chip developed could be useful for transcript profiling and for the identification of Eucalyptus trees with preferred wood quality traits in commercial breeding programmes.

  11. Profiling as a logical form of reasoning in order to solve controversial circumstances on the crime scene

    Directory of Open Access Journals (Sweden)

    Palcu Pavel

    2016-06-01

    Full Text Available While conducting research on the scene or during the entire phase of criminal prosecution, especially for the identification of the authors or settlement of the controversial circumstances, criminal profiling by a forensic psychologist will reduce the circle of suspects, as well as provide assistance in determining possible connections with other crimes and offer to judicial organs sustainable strategies for the solution of the case. In addition to identifying and processing the material traces found on the scene, concern falling strictly within forensics, in the future, efforts against criminality of the third millennium will be oriented towards the interpretation of human behaviour with criminogenic finality.

  12. Comparative study of the pharmacopeial quality and dissolution profiles of generic and other drug forms of sodium metamizole (dipyrone sold in Brazil

    Directory of Open Access Journals (Sweden)

    Morenna Alana Giordani

    2012-08-01

    Full Text Available In Brazil, in order for a pharmaceutical company to register a drug form as generic or ‘similar’ with the Brazilian food and drug agency (Anvisa, it must be proved bioequivalent to its innovatory branded form (reference drug. This requires comparative trials, carried out in conformity with official compendia (Brazilian Pharmacopeia or another officially recognized code. Additionally, according to the Anvisa resolution RDC 31/2010, the dissolution profile of the drug must be tested and compared with that of the branded reference, as a benchmark of quality. The aim of this study was to assess the quality of 500 mg sodium metamizole (dipyrone tablets produced by seven different laboratories in Brazil: three generic drugs (G1, G2, G3, three (branded similar drugs (S1, S2,S3 and their reference branded product (Novalgina®, Sanofi-Aventis, drug R. All tests were carried out by methods specified in the Brazilian Pharmacopeia 4th edition (Farmacopeia Brasileira IV. The following tests were performed: uniformity of mass, friability, disintegration time, hardness, assay, uniformity of dosage units, salicylic acid limit assay, dissolution and identification. The dissolution profile was also recorded, as recommended in RDC 31/2010. Whereas every sample was approved in all the Farmacopeia Brasileira IV tests, the results in the dissolution profile test showed that four of the test drugs (G1, G2, S1 and S2 were notpharmaceutically equivalent to drug R. Thus, only drugs G3 and S3 showed dissolution profiles similar to that of drug R and the other four drugs could not be considered equivalent to it and were not approved.

  13. In vitro dissolution profile study of mucolytic drug ambroxol hydrochloride from solid oral dosage form by UHPLC-MS/MS

    Directory of Open Access Journals (Sweden)

    Vujović Maja M.

    2017-01-01

    Full Text Available In this paper a simplified dissolution test was performed for the release of ambroxol from tablets according to the European Pharmacopoeia. In vitro, three different dissolution media; 0.1 M HCl pH 1.2, acetate buffer (ABS pH 4.5 and phosphate buffer (PBS pH 6.8 were used for the simulation of the gastrointestinal conditions at temperature of 37.0±0.5°C. The drug release was evaluated by a new ultra - high performance liquid chromatography (UHPLC - tandem mass spectrometry (MS/MS method. The method was validated to meet requirements as per ICH guidelines which include linearity, specificity, precision, accuracy and robustness. The corresponding dissolution profiles showed more than 80% drug release within 30 minutes without significant differences. Further, the developed and validated UHPLC-MS/MS method could find a useful application in the process of production, quality control and bioavailability/bioequivalence studies of new pharmaceutical formulations of drugs in order to achieve a safe therapeutic efficacy. [Projekat Ministarstva nauke Republike Srbije, br. 175045

  14. First trimester trophoblasts forming endothelial-like tubes in vitro emulate a 'blood vessel development' gene expression profile.

    Science.gov (United States)

    Highet, Amanda R; Buckberry, Sam; Mayne, Benjamin T; Khoda, Sultana M; Bianco-Miotto, Tina; Roberts, Claire T

    2016-07-01

    Extravillous cytotrophoblasts isolated from first trimester placenta, and immortalised cell lines derived from them, have the intrinsic ability to form endothelial-like tubes when cultured on Matrigel™ extracellular matrix. This in vitro tube formation may model placental angiogenesis and/or endovascular differentiation by trophoblasts. To interpret the relevance of this phenomenon to placental development, we used a gene expression microarray approach to identify which genes and pathways are associated with the tube-forming phenotype of HTR8/SVneo first trimester trophoblasts (HTR8-M), compared with HTR8/SVneo not forming tubes on plastic culture surface (HTR8-P). Furthermore, we used weighted gene co-expression network analysis (WGCNA) of microarray data to identify modules of co-expressed genes underlying the biological processes. There were 481 genes differentially expressed between HTR8-M and HTR8-P and these were significantly enriched for blood vessel development and related gene ontologies. WGCNA clustered the genes into 9 co-expression modules. One module was significantly associated with HTR8-M (p = 1.15E-05) and contained genes involved in actin cytoskeleton organization, cell migration and blood vessel development, consistent with tube formation on Matrigel. Another module was significantly associated with HTR8-P (p = 1.94E-05) and was enriched for genes involved in mitosis, consistent with proliferation by cells on plastic which do not differentiate. Up-regulation of angiogenesis and vascular development pathways in endovascular trophoblasts in vivo could underpin spiral artery remodelling processes, which are defective in preeclamptic pregnancies. Copyright © 2016 Elsevier B.V. All rights reserved.

  15. New EdF's three challenges; Les trois defis du nouvel EdF

    Energy Technology Data Exchange (ETDEWEB)

    Lepetit, V

    2005-11-15

    The opening of 15% of Electricite de France (EdF) capital to the private sector will allow the first world electric utility to raise 7 billions of euros of cash flow. EdF will have also to face the new European situation: a strained market, several consolidations to come and many competitors to deal with. EdF has to re-launch its production tool and to reinforce its interconnection capacities if it wants to stay the number one of power exports in Europe. The integration of Edison company (Italy) by EdF gives access to new gas capacities but other resources have to be found if EdF wants to enlarge its gas offer. A new concentration era is foreseen in Europe and EdF will have to seize the economic growth opportunities in particular in Europe and China. (J.S.)

  16. Metabolomic profiling unravels DNA adducts in human breast that are formed from peroxidase mediated activation of estrogens to quinone methides.

    Directory of Open Access Journals (Sweden)

    Nilesh W Gaikwad

    Full Text Available Currently there are three major hypotheses that have been proposed for estrogen induced carcinogenicity, however exact etiology remains unknown. Based on the chemical logic, studies were undertaken to investigate if estrogens could generate quinone methides in an oxidative environment which then could cause DNA damage in humans. In presence of MnO2 estrogens were oxidized to quinone methides. Surprisingly quinone methides were found to be stable with t1/2 of 20.8 and 4.5 min respectively. Incubation of estrogens with lactoperoxidase (LPO and H2O2 resulted in formation of respective quinone methides (E1(E2-QM. Subsequent addition of adenine to the assay mixture lead to trapping of E1(E2-QM, resulting in formation of adenine adducts of estrogens, E1(E2-9-N-Ade. Targeted ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS based metabolomic analysis of the breast tissue extracts showed the presence of adenine adducts of estrogens, E1(E2-9-N-Ade, along with other estrogen related metabolites. Identity of E1(E2-N-Ade in LPO assay extracts and breast tissue extracts were confirmed by comparing them to pure synthesized E1(E2-9-N-Ade standards. From these results, it is evident that peroxidase enzymes or peroxidase-like activity in human breast tissue could oxidize estrogens to electrophilic and stable quinone methides in a single step that covalently bind to DNA to form adducts. The error prone repair of the damaged DNA can result in mutation of critical genes and subsequently cancer. This article reports evidence for hitherto unknown estrogen metabolic pathway in human breast, catalyzed by peroxidase, which could initiate cancer.

  17. Large-Scale microRNA Expression Profiling Identifies Putative Retinal miRNA-mRNA Signaling Pathways Underlying Form-Deprivation Myopia in Mice.

    Science.gov (United States)

    Tkatchenko, Andrei V; Luo, Xiaoyan; Tkatchenko, Tatiana V; Vaz, Candida; Tanavde, Vivek M; Maurer-Stroh, Sebastian; Zauscher, Stefan; Gonzalez, Pedro; Young, Terri L

    2016-01-01

    Development of myopia is associated with large-scale changes in ocular tissue gene expression. Although differential expression of coding genes underlying development of myopia has been a subject of intense investigation, the role of non-coding genes such as microRNAs in the development of myopia is largely unknown. In this study, we explored myopia-associated miRNA expression profiles in the retina and sclera of C57Bl/6J mice with experimentally induced myopia using microarray technology. We found a total of 53 differentially expressed miRNAs in the retina and no differences in miRNA expression in the sclera of C57BL/6J mice after 10 days of visual form deprivation, which induced -6.93 ± 2.44 D (p myopia. We also identified their putative mRNA targets among mRNAs found to be differentially expressed in myopic retina and potential signaling pathways involved in the development of form-deprivation myopia using miRNA-mRNA interaction network analysis. Analysis of myopia-associated signaling pathways revealed that myopic response to visual form deprivation in the retina is regulated by a small number of highly integrated signaling pathways. Our findings highlighted that changes in microRNA expression are involved in the regulation of refractive eye development and predicted how they may be involved in the development of myopia by regulating retinal gene expression.

  18. DNA barcoding and LC-MS metabolite profiling of the lichen-forming genus Melanelia: Specimen identification and discrimination focusing on Icelandic taxa.

    Science.gov (United States)

    Xu, Maonian; Heidmarsson, Starri; Thorsteinsdottir, Margret; Eiriksson, Finnur F; Omarsdottir, Sesselja; Olafsdottir, Elin S

    2017-01-01

    Taxa in the genus Melanelia (Parmeliaceae, Ascomycota) belong to a group of saxicolous lichens with brown to black foliose thalli, which have recently undergone extensive changes in circumscription. Taxa belonging to Parmeliaceae are prolific producers of bioactive compounds, which have also been traditionally used for chemotaxonomic purposes. However, the chemical diversity of the genus Melanelia and the use of chemical data for species discrimination in this genus are largely unexplored. In addition, identification based on morphological characters is challenging due to few taxonomically informative characters. Molecular identification methods, such as DNA barcoding, have rarely been applied to this genus. This study aimed to identify the Melanelia species from Iceland using DNA barcoding approach, and to explore their chemical diversity using chemical profiling. Chemometric tools were used to see if lichen metabolite profiles determined by LC-MS could be used for the identification of Icelandic Melanelia species. Barcoding using the fungal nuclear ribosomal internal transcribed spacer region (nrITS) successfully identified three Melalenlia species occurring in Iceland, together with Montanelia disjuncta (Basionym: Melanelia disjuncta). All species formed monophyletic clades in the neighbor-joining nrITS gene tree. However, high intraspecific genetic distance of M. stygia suggests the potential of unrecognized species lineages. Principal component analysis (PCA) of metabolite data gave a holistic overview showing that M. hepatizon and M. disjuncta were distinct from the rest, without the power to separate M. agnata and M. stygia due to their chemical similarity. Orthogonal partial least-squares to latent structures-discriminate analysis (OPLS-DA), however, successfully distinguished M. agnata and M. stygia by identifying statistically significant metabolites, which lead to class differentiation. This work has demonstrated the potential of DNA barcoding, chemical

  19. TED-Ed lessons & TED-Ed clubs: Educational activities to amplify students' voices

    Science.gov (United States)

    Villias, Georgios

    2017-04-01

    TED-Ed lessons and TED-Ed clubs are two powerful educational tools that can be used in today's school classrooms in order to create an educational environment that is engaging for the students and favors their active participation, created and fostered by TED-Ed. TED-Ed is TED's educational initiative, committed to create lessons worth sharing and amplify the voices and ideas of teachers and students around the world. TED-Ed animated lessons are fully organized lessons structured around an animated video that introduces new topics to learners in an exciting, thought-provoking way. These lessons have been created as a result of the cooperation between expert educators and animators and have been uploaded at the TED-Ed platform (http://ed.ted.com). On the other hand, TED-Ed Clubs are also an interesting way to offer students the chance, the voice and the opportunity to express their thoughts, engage actively on these matters and connect with each other, both at a local, as well as at an international level (http://ed.ted.com/clubs). By developing new TED-Ed lessons or by customizing appropriately existing animated TED-Ed lessons (translating, modifying the questions asked, introducing new discussion topics), I have created and implemented in my student-centered, didactic approach, a series of TED-ED animated lessons directly connected with the Greek national science syllabus that were used to spark students curiosity and initiate a further analytical discussion or introduce other relevant educational activities (http://gvillias.wixsite.com/education). Furthermore, at my school, we established Varvakeio TED-Ed Club, an environment that supports and empowers our students to research, develop and disseminate their own personal ideas that worth spreading. During the year, our members were inspired by watching TED talks presented by experts on their field on various different areas, including social, economical, environmental and technological-scientific issues. Our aim

  20. Inside the Sex Ed Studio: An Interview with Susan N. Wilson

    Science.gov (United States)

    Taverner, William J.

    2007-01-01

    "Inside the Sex Ed Studio" profiles leaders in the field of sexuality education. Susan N. Wilson, former Executive Coordinator of the Network for Family Life Education, long-time advocate for sexuality education, and the driving force behind New Jersey's K-12 mandate for comprehensive sexuality education was the first such leader to be…

  1. Effectiveness of Mutual Learning Approach in the Academic Achievement of B.Ed Students in Learning Optional II English

    Science.gov (United States)

    Arulselvi, Evangelin

    2013-01-01

    The present study aims at finding out the effectiveness of Mutual learning approach over the conventional method in learning English optional II among B.Ed students. The randomized pre-test, post test, control group and experimental group design was employed. The B.Ed students of the same college formed the control and experimental groups. Each…

  2. Ed Lorenz: Father of the 'Butterfly Effect'

    Indian Academy of Sciences (India)

    IAS Admin

    Ed Lorenz, rightfully acclaimed as the father of the 'Butterfly Effect', was an American math- ematician and meteorologist whose early work on weather prediction convinced the world at large about the unpredictability of weather. His seminal work on a simplified model for convec- tions in the atmosphere led to the modern ...

  3. (ED) by men in Edo state, Nigeria

    African Journals Online (AJOL)

    E. (Eshiobo) Irekpita

    2017-05-03

    May 3, 2017 ... of men in Edo state with regards to ED. The secondary objective .... Variables with sta- tistically significant correlation with IIEF score were respondents' location (P = 0.000), respondents' educational level (P = 0.000), number of wives (P ... between this variable and the level of education of the respondents.

  4. Clinical outcomes of ED patients with bandemia.

    Science.gov (United States)

    Shi, Eileen; Vilke, Gary M; Coyne, Christopher J; Oyama, Leslie C; Castillo, Edward M

    2015-07-01

    Although an elevated white blood cell count is a widely utilized measure for evidence of infection and an important criterion for evaluation of systemic inflammatory response syndrome, its component band count occupies a more contested position within clinical emergency medicine. Recent studies indicate that bandemia is highly predictive of a serious infection, suggesting that clinicians who do not appreciate the value of band counts may delay diagnosis or overlook severe infections. Whereas previous studies focused on determining the quantitative value of the band count (ie, determining sensitivity, threshold for bandemia, etc.), this study directs attention to patient-centered outcomes, hypothesizing that the degree of bandemia predisposes patients to subsequent negative clinical outcomes associated with underappreciated severe infections. This retrospective study of electronic medical records includes patients who initially presented to the emergency department (ED) with bandemia and were subsequently discharged from the ED. These patients were screened for repeat ED visits within 7 days and death within 30 days. In patients with severe bandemia who were discharged from the ED, there was a 20.9% revisit rate at 7 days and a 4.9% mortality rate at 30 days, placing severely bandemic patients at 5 times significantly greater mortality compared to nonbandemic patients (P = .032). Our review of patient outcomes suggests that the degree of bandemia, especially in the setting of concurrent tachycardia or fever, is associated with greater likelihood of negative clinical outcomes. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. Sustainable Mechanism to Reduce Emergency Department (ED) Length of Stay: The Use of ED Holding (ED Transition) Orders to Reduce ED Length of Stay.

    Science.gov (United States)

    Haydar, Samir A; Strout, Tania D; Baumann, Michael R

    2016-07-01

    The objective was to evaluate the effect of an emergency clinician-initiated "ED admission holding order set" on emergency department (ED) treatment times and length of stay (LOS). We further describe the impact of a performance improvement strategy with sequential plan-do-study-act (PDSA) cycles used to influence the primary outcome measures, ED LOS, and disposition decision to patient gone (DDTPG) time, for admitted patients. We developed and implemented an expedited, emergency physician-facilitated admission protocol that bypassed typical inpatient workflows requiring inpatient evaluations prior to the placement of admission orders. During the 48-month study period, ED flow metrics generated during the care of 27,580 admissions from the 24-month period prior to the intervention were compared to the 29,978 admissions that occurred during the 24-month period following the intervention. The intervention was the result of an in-depth, five-phase PDSA cycle quality improvement intervention evaluating ED flow, which identified the requirement of bedside inpatient evaluations prior admission order placement as being a "non-value-added" activity. ED output flow metrics evaluating the admission process were tracked for 24 months following the intervention and were compared to the 24 months prior. The use of an emergency physician-initiated admission holding order protocol resulted in sustainable reductions in ED LOS when comparing the 2 years prior to the intervention, with median LOS of 410 (interquartile range [IQR] = 295 to 543) and 395 (IQR = 283 to 527) minutes, to the 2 calendar years following the intervention, with the median LOS of 313 (IQR = 21 to 431) and 316 (IQR = 224 to 438) minutes, respectively. This overall reduction in ED LOS of nearly 90 minutes was found to be primarily the result of a decrease in the time from the emergency physician's admitting DDTPG times with median times of 219 (IQR = 150 to 306) and 200 (IQR = 136 to 286) minutes for the 2 years

  6. New Zealand's emergency department target - did it reduce ED length of stay, and if so, how and when?

    Science.gov (United States)

    Tenbensel, Tim; Chalmers, Linda; Jones, Peter; Appleton-Dyer, Sarah; Walton, Lisa; Ameratunga, Shanthi

    2017-09-26

    In 2009, the New Zealand government introduced a hospital emergency department (ED) target - 95% of patients seen, treated or discharged within 6 h - in order to alleviate crowding in public hospital EDs. While these targets were largely met by 2012, research suggests that such targets can be met without corresponding overall reductions in ED length-of-stay (LOS). Our research explores whether the NZ ED time target actually reduced ED LOS, and if so, how and when. We adopted a mixed-methods approach with integration of data sources. After selecting four hospitals as case study sites, we collected all ED utilisation data for the period 2006 to 2012. ED LOS data was derived in two forms-reported ED LOS, and total ED LOS - which included time spent in short-stay units. This data was used to identify changes in the length of ED stay, and describe the timing of these changes to these indicators. Sixty-eight semi-structured interviews and two surveys of hospital clinicians and managers were conducted between 2011 and 2013. This data was then explored to identify factors that could account for ED LOS changes and their timing. Reported ED LOS reduced in all sites after the introduction of the target, and continued to reduce in 2011 and 2012. However, total ED LOS only decreased from 2008 to 2010, and did not reduce further in any hospital. Increased use of short-stay units largely accounted for these differences. Interview and survey data showed changes to improve patient flow were introduced in the early implementation period, whereas increased ED resources, better information systems to monitor target performance, and leadership and social marketing strategies mainly took throughout 2011 and 2012 when total ED LOS was not reducing. While the ED target clearly stimulated improvements in patient flow, our analysis also questions the value of ED targets as a long term approach. Increased use of short-stay units suggests that the target became less effective in 'standing

  7. Risk factors for ED use among homeless veterans.

    Science.gov (United States)

    Tsai, Jack; Rosenheck, Robert A

    2013-05-01

    Despite national concern about homeless veterans, there has been little examination of their use of emergency department (ED) services. This study examines factors related to the use of ED services in the Veterans Affairs (VA) healthcare system, where insurance is not a barrier to ambulatory healthcare. National VA administrative data from fiscal year 2010 are used to describe the proportions of ED users among homeless and domiciled VA patients. A case-control design is then used to compare homeless ED and non-ED users on sociodemographic and clinical correlates, as well as use of ambulatory care and psychotropic medications. Sixteen percent of domiciled VA patients used EDs at least once during the year and 1% were frequent ED users (>4 ED visits) compared to 45% of homeless VA patients, 10% who were frequent ED users. Among homeless VA patients, those who used EDs were more likely to have a range of psychiatric and medical conditions, and had more service visits and psychotropic medication prescriptions than non-ED users. Multivariate analyses suggest their risk for psychiatric and medical conditions increase their likelihood of using ED services. The high rate of ED use among homeless veterans is associated with significant morbidity, but also greater use of ambulatory care and psychotropics suggesting their ED use may reflect unmet psychosocial needs. Published by Elsevier Inc.

  8. Evaluation of P2X7 receptor expression in peripheral lymphocytes and immune profile from patients with indeterminate form of Chagas disease.

    Science.gov (United States)

    Souza, Viviane do Carmo Gonçalves; Dos Santos, Joabel Tonellotto; Cabral, Fernanda Licker; Barbisan, Fernanda; Azevedo, Maria Isabel; Dias Carli, Luiz Felipe; de Avila Botton, Sonia; Dos Santos Jaques, Jeandre Augusto; Rosa Leal, Daniela Bitencourt

    2017-03-01

    Chagas disease (CD) is caused by Trypanosoma cruzi, an intracellular protozoan which is a potent stimulator of cell-mediated immunity. In the indeterminate form of CD (IFCD) a modulation between pro- and anti-inflammatory responses establishes a host-parasite adaptation. It was previously demonstrated that purinergic ecto-enzymes regulates extracellular ATP and adenosine levels, influencing immune and inflammatory processes during IFCD. In inflammatory sites ATP, as well as its degradation product, adenosine, function as signaling molecules and immunoregulators through the activation of purinergic receptors. In this work, it was analyzed the gene and protein expression of P2X7 purinergic receptor in peripheral lymphocytes and serum immunoregulatory cytokines from IFCD patients. Gene and protein expression of P2X7 receptor (P2X7R), and serum cytokines (IL-2, IL-10, IL-17 and IFN-γ) were unaltered. However, IFCD group showed significantly higher IL-4 and IL-6 levels while TNF-α was significantly decreased. These results indicate that imune profile of IFCD patients displays anti-inflammatory characteristics, consistent with the establishment of an immunomodulatory response. Further study about the molecular knowledge of P2X7R in IFCD is useful to clarify the participation of purinergic system in the regulatory mechanism which avoid the progression of CD. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. Cation profiling of passive films on stainless steel formed in sulphuric and acetic acid by deconvolution of angle-resolved X-ray photoelectron spectra

    Energy Technology Data Exchange (ETDEWEB)

    Högström, Jonas, E-mail: jhogstrom@gmail.com; Fredriksson, Wendy, E-mail: wendy.fredriksson@kemi.uu.se; Edstrom, Kristina, E-mail: kristina.edstrom@kemi.uu.se; Björefors, Fredrik, E-mail: fredrik.bjorefors@kemi.uu.se; Nyholm, Leif, E-mail: leif.nyholm@kemi.uu.se; Olsson, Claes-Olof A., E-mail: drclabbe@kth.se

    2013-11-01

    An approach for determining depth gradients of metal-ion concentrations in passive films on stainless steel using angle-resolved X-ray photoelectron spectroscopy (ARXPS) is described. The iterative method, which is based on analyses of the oxidised metal peaks, provides increased precision and hence allows faster ARXPS measurements to be carried out. The method was used to determine the concentration depth profiles for molybdenum, iron and chromium in passive films on 316L/EN 1.4432 stainless steel samples oxidised in 0.5 M H{sub 2}SO{sub 4} and acetic acid diluted with 0.02 M Na{sub 2}B{sub 4}O{sub 7} · 10H{sub 2}O and 1 M H{sub 2}O, respectively. The molybdenum concentration in the film is pin-pointed to the oxide/metal interface and the films also contained an iron-ion-enriched surface layer and a chromium-ion-dominated middle layer. Although films of similar composition and thickness (i.e., about 2 nm) were formed in the two electrolytes, the corrosion currents were found to be three orders of magnitude larger in the acetic acid solution. The differences in the layer composition, found for the two electrolytes as well as different oxidation conditions, can be explained based on the oxidation potentials of the metals and the dissolution rates of the different metal ions.

  10. Autonomic symptom burden in the hypermobility type of Ehlers-Danlos syndrome: a comparative study with two other EDS types, fibromyalgia, and healthy controls.

    Science.gov (United States)

    De Wandele, Inge; Calders, Patrick; Peersman, Wim; Rimbaut, Steven; De Backer, Tine; Malfait, Fransiska; De Paepe, Anne; Rombaut, Lies

    2014-12-01

    This study provides insight into the profile and importance of autonomic symptoms in the hypermobility type (HT) of Ehlers-Danlos syndrome (EDS). The impact of these symptoms is put into perspective by comparing with fibromyalgia (FM) and two other EDS types. Overall, 80 patients with EDS-HT participated, as well as 11 with classical EDS (cEDS), seven with vascular EDS (vEDS), 38 with FM, and 43 healthy controls. All participants filled out the autonomic symptom profile (ASP). Furthermore, they were inquired about quality of life (QOL, SF-36) and factors contributing to the EDS disease burden, e.g., hypermobility (5-point questionnaire, GHQ), fatigue (checklist individual strength, CIS), pain (pain detect questionnaire, PDQ), affective distress (hospital anxiety and depression scale, HADS), and physical activity (Baecke). The total autonomic symptom burden was higher in EDS-HT (57.9 ± 21.57) than in controls (11.3 ± 19.22), cEDS (32.3 ± 19.47), and vEDS (29.1 ± 19.18), but comparable to FM (53.8 ± 19.85). Especially orthostatic and gastrointestinal complaints were prevalent. The importance of autonomic symptoms in EDS-HT was emphasized by the correlation with lowered QOL (r = -0.402), fatigue (r = 0.304), and pain severity (r = 0.370). Although affective distress and decreased physical activity are often suggested as possible causes for dysautonomia, the ASP did not correlate with the HADS and Baecke score. By contrast, the correlation of the GHQ (r = 0.298) and PDQ (r = 0.413) with the ASP supports the hypothesis that joint hypermobility and neuropathy may play a role in the development of autonomic symptoms. Autonomic symptoms, especially orthostatic and gastrointestinal complaints, are frequent extraarticular manifestations of EDS-HT and contribute to the disease burden. Copyright © 2014 Elsevier Inc. All rights reserved.

  11. EDS V26 Containment Vessel Explosive Qualification Test Report

    Energy Technology Data Exchange (ETDEWEB)

    Crocker, Robert W. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Haroldsen, Brent L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Stofleth, Jerome H. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2013-11-01

    The objective of the test was to qualify the vessel for its intended use by subjecting it to a 1.25 times overtest. The criteria for success are that the measured strains do not exceed the calculated strains from the vessel analysis, there is no significant additional plastic strain on subsequent tests at the rated design load (shakedown), and there is no significant damage to the vessel and attached hardware that affect form, fit, or function. Testing of the V25 Vessel in 2011 established a precedent for testing V26 [2]. As with V25, two tests were performed to satisfy this objective. The first test used 9 pounds of Composition C-4 (11.25 lbs. TNT-equivalent), which is 125 percent of the design basis load. The second test used 7.2 pounds of Composition C-4 (9 lbs. TNT-equivalent) which is 100 percent of the design basis load. The first test provided the required overtest while the second test served to demonstrate shakedown and the absence of additional plastic deformation. Unlike the V25 vessel, which was mounted in a shipping cradle during testing, the V26 vessel was mounted on the EDS P2U3 trailer prior to testing. Visual inspections of the EDS vessel, surroundings, and diagnostics were completed before and after each test event. This visual inspection included analyzing the seals, fittings, and interior surfaces of the EDS vessel and documenting any abnormalities or damages. Photographs were used to visually document vessel conditions and findings before and after each test event.

  12. edX e-learning course development

    CERN Document Server

    Gilbert, Matthew A

    2015-01-01

    If you are an educator creating a course for edX or a corporate trainer using Open edX for large-scale learning and development initiatives, then edX E-Learning Course Development is the ideal book for you.

  13. La Costituzione Islandese: storia ed evoluzione

    Directory of Open Access Journals (Sweden)

    Fabio Quartino

    2011-03-01

    Full Text Available "La Costituzione Islandese: storia ed evoluzione" is a degree thesis defended on 15th July 2009 by Fabio Quartino under the supervision of Prof. Andrea Canepa of the University of Genoa, Italy. It offers an extensive overview of Icelandic history aimed at finding out the roots of the nation's constitutional order, which is currently in the process of being revised by the first ever elected constitutional assembly in the life of the country. Fabio Quartino's work wishes to be a source of useful information for Italian-speaking scholars who have an interest in Iceland's constitutional history and may not have access to comprehensive overviews in their native tongue.

  14. MGS RS: IONOSPHERIC ELECTRON DENSITY PROFILES V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — This data set contains 5600 ionospheric electron density profiles (EDS files) derived from Mars Global Surveyor (MGS) radio occultation data. The profiles were...

  15. Association between level of personality organization as assessed with theory-driven profiles of the Dutch Short Form of the MMPI and outcome of inpatient treatment for personality disorder

    NARCIS (Netherlands)

    Scholte, W.R.; Eurelings-Bontekoe, E.H.M.; Tiemens, B.G.; Verheul, R.; Meerman, A.; Hutschemaekers, G.J.M.

    2014-01-01

    The association between level of personality organization as assessed by theory-driven profile interpretation of the MMPI (Hathaway & McKinley, 1943) Dutch Short Form and treatment outcome was investigated in a naturalistic follow-up study among 121 psychotherapy inpatients who had been treated for

  16. Differential treatment response of subtypes of patients with borderline personality organization, as assessed with theory-driven profiles of the Dutch short form of the MMPI: a naturalistic follow-up study

    NARCIS (Netherlands)

    Eurelings-Bontekoe, E.H.M.; Peen, J.; Noteboom, A.; Alkema, M.; Dekker, J.J.M.

    2012-01-01

    We investigated the validity of different subtypes of borderline personality organization (BPO) as assessed by theory-driven profiles of the Minnesota Multiphasic Personality Disorder (MMPI; Hathaway & McKinley, 1943) Dutch Short Form (DSFM; Eurelings-Bontekoe, Onnink, Williams, & Snellen, 2008) in

  17. Perceptions of empowerment among ED nurses.

    Science.gov (United States)

    DeVivo, Diane; Quinn Griffin, Mary T; Donahue, Moreen; Fitzpatrick, Joyce J

    2013-11-01

    Nurses' perceptions of empowerment have been linked to a number of variables in the hospital workplace, including job satisfaction, autonomy, and work effectiveness. Yet there have been no previous studies of perceptions of empowerment specifically among emergency department (ED) nurses. Registered nurses (RNs) employed in the EDs of 6 hospitals in a major health care system in the eastern United States were surveyed regarding their perceptions of empowerment. Of the 240 RNs eligible to participate, there were 167 usable surveys. There was a moderate level of empowerment among the RNs who participated, consistent with the level of empowerment reported in several other studies of staff nurses and nurses in other positions. The moderate level of empowerment in this sample may be attributed to the many opportunities for RN involvement in the hospitals within this health care system. Nurse leaders can initiate programs focused on enhancing RN perceptions of empowerment. In addition, there is a need for further research among RNs with different specialty preparation. Copyright © 2013. Published by Mosby, Inc.

  18. Water in star-forming regions with Herschel (WISH). IV. A survey of low-J H2O line profiles toward high-mass protostars

    Science.gov (United States)

    van der Tak, F. F. S.; Chavarría, L.; Herpin, F.; Wyrowski, F.; Walmsley, C. M.; van Dishoeck, E. F.; Benz, A. O.; Bergin, E. A.; Caselli, P.; Hogerheijde, M. R.; Johnstone, D.; Kristensen, L. E.; Liseau, R.; Nisini, B.; Tafalla, M.

    2013-06-01

    Context. Water is a key constituent of star-forming matter, but the origin of its line emission and absorption during high-mass star formation is not well understood. Aims: We study the velocity profiles of low-excitation H2O lines toward 19 high-mass star-forming regions and search for trends with luminosity, mass, and evolutionary stage. Methods: We decompose high-resolution Herschel-HIFI line spectra near 990, 1110 and 1670 GHz into three distinct physical components. Dense cores (protostellar envelopes) are usually seen as narrow absorptions in the H2O 1113 and 1669 GHz ground-state lines, the H2O 987 GHz excited-state line, and the H218O 1102 GHz ground-state line. In a few sources, the envelopes appear in emission in some or all studied lines, indicating higher temperatures or densities. Broader features due to outflows are usually seen in absorption in the H2O 1113 and 1669 GHz lines, in 987 GHz emission, and not seen in H218O, indicating a lower column density and a higher excitation temperature than the envelope component. A few outflows are detected in H218O, indicating higher column densities of shocked gas. In addition, the H2O 1113 and 1669 GHz spectra show narrow absorptions by foreground clouds along the line of sight. The lack of corresponding features in the 987 GHz and H218O lines indicates a low column density and a low excitation temperature for these clouds, although their derived H2O ortho/para ratios are close to 3. Results: The intensity of the ground state lines of H2O at 1113 and 1669 GHz does not show significant trends with source luminosity, envelope mass, or evolutionary state. In contrast, the flux in the excited-state 987 GHz line appears correlated with luminosity and the H218O line flux appears correlated with the envelope mass. Furthermore, appearance of the envelope in absorption in the 987 GHz and H218O lines seems to be a sign of an early evolutionary stage, as probed by the mid-infrared brightness and the Lbol/Menv ratio of

  19. Bike Ed '77: A Conference Report (Washington, D.C., May 4-6, 1977).

    Science.gov (United States)

    Johnson (Lawrence) and Associates, Inc., Washington, DC.

    As a result of intensified need for sound safety education programs for both young and mature bicyclists due to the dramatic increase in bicycling as a form of transportation and recreation, the first national conference on bicyclist safety education was held--Bike Ed '77. Major purposes of the conference were to stimulate communication among…

  20. Modified Berlekamp—Massey algorithm 243 of examples illustrate ...

    Indian Academy of Sciences (India)

    white noise' sequence. 2. Modified recursive form of the Berlekamp-Massey algorithm. We are here interested in modelling data as the impulse response of a discrete linear. filter, the objective being to obtain a minimal representation by such a ...

  1. Stanislaw Widlak (ed.), Italianità ed Italianistica nell'Europa Centrale ...

    African Journals Online (AJOL)

    User

    nel futuro ad intensi scambi e collaborazioni tra italianisti che sono necessari allo sviluppo ed alla crescita di ogni disciplina. I partecipanti al congresso sono stati circa una cinquantina, tra studiosi e studenti, provenienti da una ventina di università e da una dozzina di paesi. Gli argomenti trattati nei loro interventi sono stati ...

  2. Development of the Addiction Profile Index Internet Addiction Form (APIINT): Validity and Reliability/Bagimlilik Profil Indeksi Internet Bagimliligi Formu'nun (BAPINT) gelistirilmesi: Geçerlik ve güvenilirligi

    National Research Council Canada - National Science Library

    Kultegin Ogel; Figen Karadag; Defne Satgan; Ceren Koc

    2015-01-01

      To adapt the Addiction Profile Index (API) for internet use and addiction in order to develop an internet addiction questionnaire better suited to the definition of addiction to be used for clinical purposes...

  3. Teaching Form as Form

    DEFF Research Database (Denmark)

    Keiding, Tina Bering

    2012-01-01

    , this book offers both inspiration to teaching form and a systematic framework for pedagogical and didactical reflection on this topic. In this sense, it shapes and professionalizes design teaching, and contributes to the development of the double-professionalism, which is so essential for teachers in modern...... means that form serves both as the connective value and as the concept for reflection. In other words, form is observed as form, not anything else. The didactical challenge of teaching form as form is accentuated by students’ everyday-based pre-orientation towards function at the expense of form...... in this book that they are highly interested in both the declarative and formative dimension of making form. Methodologically, the courses described in the contributions have a strong focus on student-centered experiential activities, thereby implicitly claiming that students must learn to make form...

  4. Citar e referenciar : APA 6ª ed.

    OpenAIRE

    Marcos, Isabel Marques

    2016-01-01

    A elaboração correta dos trabalhos científicos pressupõe o respeito por um conjunto de princípios normativos de citação e referenciação bibliográfica que salvaguardam os autores das criações intelectuais do uso indevido das mesmas. Partindo de três conceitos: citação, referência bibliográfica e lista de referências apresentam-se as normas da APA 6ª ed. nos seus elementos essenciais. Estas normas, da área da informação e documentação, definem regras para a normalização das referências bibliogr...

  5. Giocare, tra violenza ed ecologia della mente.

    Directory of Open Access Journals (Sweden)

    Enrico Euli

    2008-07-01

    Full Text Available L'articolo riflette sulle relazioni tra comunicazione, violenza e gioco, nel tentativo di rintracciare tra loro convergenze, affinità e contrasti. Le nostre relazioni, infatti, ci immettono inerzialmente in dilemmi e paradossi di così alta complessità da rendere spesso inadeguati gli strumenti 'logici' ed 'analitici': dal che può derivare un senso di impotenza, rabbia, paralisi, ma anche un desiderio potente di controllo e di soluzione degli eventi. Entrambe queste strade ci conducono dentro le false alternative della violenza. La cultura del gioco, invece, ci propone (attraverso le sue pratiche, ma anche negli scritti teorici di Freud, Winnicott, Bateson, qui riassunti e rivisitati una modalità più creativa e nonviolenta, più prossima ad un' ecologia della mente e ad un'estetica delle emozioni.

  6. Influence of MgO containing strontium on the structure of ceramic film formed on grain oriented silicon steel surface

    Directory of Open Access Journals (Sweden)

    Vasconcelos Daniela C. Leite

    1999-01-01

    Full Text Available The oxide layer formed on the surface of a grain oriented silicon steel was characterized by SEM and EDS. 3% Si steel substrates were coated by two types of slurries: one formed by MgO and water and other formed by MgO, water and SrSO4. The ceramic films were evaluated by SEM, EDS and X-ray diffraction. Depth profiles of Fe, Si and Mg were obtained by GDS. The magnetic core losses (at 1.7 Tesla, 60 Hz of the coated steel samples were evaluated as well. The use of MgO containing strontium reduced the volume fraction of forsterite particles beneath the outermost ceramic layer. It was observed a reduced magnetic core loss with the use of the slurry with MgO containing strontium.

  7. Triage quality control is missing tools-a new observation technique for ED quality improvement.

    Science.gov (United States)

    Malmström, Tomi; Harjola, Veli-Pekka; Torkki, Paulus; Kumpulainen, Salla; Malmström, Raija

    2017-04-01

    Correct assessment of patient urgency is critical to ensuring patient safety in emergency departments (EDs). Although significant time and effort have been devoted to developing triage systems, less attention has been paid to the development of quality control. The aim of this study is to introduce and test observation technique, which enables identifying of patient groups at risk of erroneous assessment in triage. The introduced technique is aimed to be less laborious to use than existing triage quality control methods. The study developed an observation technique for identifying patients with possible erroneous assessments in triage. Data sample for the observation technique is carried out with survey form filled in by nurse. Hospital ED with ~74 000 patient visits annually. Consecutive adult patients in an ED for baseline study period of 14 days (1774 patients) in 2010 and control study period of 4 days (541 patients) in 2012. Triage observation technique for continuous improvement of triage performance. Primary measures of triage improvement were triage accuracy and nurses' ability to predict patient admissions. With the observation technique the ED staff was able to identify patient groups at risk for erroneous triage. Under-triage related mostly to patients with chest pain, shortness of breath, collapse, stomach pain and infections. Instead injures and muscular skeletal symptoms were seldom undertriaged even though they are common. EDs can control triage quality with simple observation technique. The usability of observation technique and triage quality improvement process were good.

  8. Profilowe zróżnicowanie form żelaza i glinu w glebach pod świerczyn górnoreglową Plagiothecio-Piccetum tatricum w Gorcach jako wskaźnik aktualnych procesów glebotwórczych / Distribution of Iron and Aluminum Forms as an Indicator of Present-Day Soil-Forming Processes in Soil Profiles under Wooded Spruce Plagiothecio-Piccetum Tatricum in the Gorce Mts. (Southern Poland

    Directory of Open Access Journals (Sweden)

    Miechówka Anna

    2015-09-01

    Full Text Available The aim of the study was to determine soil-forming processes in soils formed from the Magura sandstones (Carpathian flysch under wooded spruce Plagiothecio-Piccetum tatricum in the Gorce Mts., southern Poland. The research focused on distribution of non-silicate forms of iron and aluminum in soil profiles. The content of pyrophosphate, oxalate, and dithionite phases of iron and aluminum in the genetic horizons of four soil profiles was measured and selected pedogenic factors were calculated. Based on the obtained results podzolization and brunification are dominant soil-forming processes in the studied soils. The brunification effect was more common in the soils under the large share of Athyrium distentifolium, whereas podzolization predominates in the soils where Vaccinium myrtillus prevails in forest floor. Studied soils were classified as Dystric Endoskeletic Cambisol (Loamic, Humic, Dystric Cambisol (Siltic, Humic and Skeletic Folic Albic Podzol (Arenic.

  9. Exploring personality clusters among parents of ED subjects. Relationship with parents' psychopathology, attachment, and family dynamics.

    Science.gov (United States)

    Amianto, Federico; Daga, Giovanni Abbate; Bertorello, Antonella; Fassino, Secondo

    2013-10-01

    Eating disorders are some of the most difficult mental disorders to treat and manage. Family interacts with genetic dispositions and other pathogenic factors, and may influence the outburst, development and outcome of EDs. The present study explores with a cluster analysis the personality traits of parents of ED subjects. One-hundred-eight mothers and 104 fathers were tested with Temperament Character Inventory (TCI), Eating Disorder Inventory-2 (EDI-2), State-Trait Anger Expression Inventory (STAX), Family Assessment Device (FAD), Attachment Style Questionnaire (ASQ), Symptom Questionnaire (SQ), Psychological Well-Being scales (PWB). The cluster distribution of parents based on personality traits was explored. Parents' clusters TCI scores were compared as regards personality, psychopathology, attachment and family features. Cross distribution of temperament and character clusters in mothers and fathers, among couples and ED diagnoses of the daughters was explored. Two clusters of mothers and fathers were identified with temperament clustering. Character traits led to two mothers and three fathers clusters. Mothers temperament cluster 1 (MTC1) correspond to a explosive/adventurous profile, MTC2 to a cautious/passive-dependent profile. Fathers temperament cluster 1 (FTC1) was explosive/methodic, FTC2 was independent/methodic. Character clustering distinguished very immature mothers (MCC1) and majority (65%) of character mature mothers with low self-transcendence (MCC2). A third of fathers was severely immature (FCC1), a third impaired as regards relationships (poor cooperativeness and self-transcendence; FCC2), and one third character mature fathers with low self-transcendence (FCC3). Each cluster evidences specific psychopathology and attachment characteristics. FTC1 was more frequently associated with character immaturity. No significant clusters' cross correlation was found in parental couples. Parents' clusters analyze in depth the univocal picture of

  10. Association between level of personality organization as assessed with theory-driven profiles of the Dutch Short Form of the MMPI and outcome of inpatient treatment for personality disorder.

    Science.gov (United States)

    Scholte, Wubbo R; Eurelings-Bontekoe, Elisabeth H M; Tiemens, Bea G; Verheul, Roel; Meerman, Anke; Hutschemaekers, Giel J M

    2014-01-01

    The association between level of personality organization as assessed by theory-driven profile interpretation of the MMPI (Hathaway & McKinley, 1943) Dutch Short Form and treatment outcome was investigated in a naturalistic follow-up study among 121 psychotherapy inpatients who had been treated for their severe personality pathology. Treatment outcome was measured with the Brief Symptom Inventory (De Beurs & Zitman, 2006). Personality organization was associated with severity of psychopathology at baseline, the end of treatment, and 36 months after baseline. At 36 months after baseline, all patients except those with the high-level borderline organization profile and the psychotic borderline profile maintained their improvement. Contrary to expectations, (a) personality organization did not differentiate between patients with successful and unsuccessful out-comes, and (b) patients with a neurotic personality organization did not respond better than those with a borderline personality organization. Because of the small N, conclusions are tentative.

  11. Použití formální konceptuální analýzy při hodnocení vztahů mezi prostředím vybraných metropolí České republiky a pohybovou aktivitou jejich obyvatel The use of formal concept analysis in evaluation of the relationship between the environment and physical activity of the residents in Czech regional cities

    Directory of Open Access Journals (Sweden)

    Ladislav Bláha

    2008-01-01

    Full Text Available Současným trendem co nejvěrnějšího popisu reálných jevů je interdisciplinární přístup, který s sebou přináší velké množství analyzovaných proměnných. Důraz je proto kladen na přesné statistické zpracování a co nejvýstižnější interpretaci tak velkého množství různorodých dat. Cílem studie je najít proměnné poukazující na pohybově přátelské a stimulující prostředí metropolí u randomizovaného souboru 15–65letých obyvatel Brna, Českých Budějovic, Hradce Králové, Liberce, Olomouce, Ostravy, Plzně a Ústí nad Labem pomocí metody formální konceptuální analýzy (FCA. Charakteristiky prostředí metropolí a demografické údaje jejich náhodně vybraných obyvatel (384 žen a 278 mužů byly mapovány dotazníkem ANEWS v průběhu jara a podzimu roku 2007. Současně s aplikací ANEWS dotazníku byla pomocí pedometru Yamax SW 701 monitorována týdenní pohybová aktivita (PA zúčastněných obyvatel. FCA je matematickou metodou hledání zajímavých shluků objektů z matice dat o vlastnostech analyzovaných objektů. S rostoucím denním počtem kroků z Yamaxu se u žen i mužů významně zvyšují (≥10 % následující charakteristiky prostředí – chodecky vysoce příznivé ulice, velmi příjemné okolí bydliště a chůzí dostupné služby a faktor účasti v organizované PA (≥2 krát týdně. U skupiny mužů navíc i procentuální zastoupení nekuřáků a neobézních jedinců. Pohybově přátelské a stimulující prostředí našich metropolí lze, vzhledem k dennímu počtu kroků, charakterizovat blízkou dostupností služeb, absencí slepých ulic, pěší průchodností ulic, jejich čistotou a osázením stromy. Current trends in research promote an interdisciplinary approach to the description of real conditions in the most precise way, which means a variety of variables enter into analysis. Therefore, accurate statistical analysis must be carried

  12. Completing EdTPA: TSOL Candidate Performance and Reflection

    Science.gov (United States)

    Micek, Timothy A.

    2017-01-01

    edTPA is a pre-service assessment process designed to determine if a new teacher is ready for the job. edTPA is part of a national movement towards the use of performance assessments in teacher education. As of 2014, 41 states (a) require a state-approved performance assessment like edTPA for program completion or for state licensure and/or state…

  13. 'Psych ed' helps speed throughput time by 9%.

    Science.gov (United States)

    2006-02-01

    Adequate staffing, proper location, and design of psychiatric ED services area are critical to successful implementation. One ED cut average throughput time by 9%. Have mental health workers available to determine the level of care each patient needs. Have your psych area set apart from the main ED to avoid excessive noise and confusion. Have a minimal amount of equipment in the rooms so that patients cannot harm themselves.

  14. An association between snowfall and ED presentation of cardiac arrest.

    Science.gov (United States)

    Spitalnic, S J; Jagminas, L; Cox, J

    1996-10-01

    Studies from several cities have reported increased cardiovascular mortality associated with snowfall; whether this weather also results in increased emergency department (ED) presentation of cardiac arrests is not known. A retrospective review was conducted of cardiac arrest patients presenting to a New England ED during the months of October through May, from 1991 to 1994. Comparing daily frequency of cardiac arrest patients with climactic data, a 27% increase was observed in the frequency of cardiac arrest presentation to the ED on days with snowfall (P = .0004). ED physicians and staff should anticipate an increased frequency of cardiac arrest patients on days with snowfall.

  15. Minor injury attendance times to the ED.

    LENUS (Irish Health Repository)

    Conlon, Ciaran

    2009-07-01

    The Health Service Executive (HSE) highlights the need for effective patient throughput and management, whilst providing appropriate staffing and therapeutic interventions. It acknowledges that patient need is integral to the development of a nurse led service and advocates planning staffing levels to reflect arrival times of patients. An observational study of all patients who presented to the emergency department in July 2005 and February 2006 was undertaken (n=7768). The study identified 1577 patients suitable for treatment by the Advanced Nurse Practitioner (ANP) in these two months, which represents 20% of all patient attendances to the ED in this time period. A data collection tool was devised collectively by the ANPs to identify appropriate patients. The findings of the study revealed that 73% of patients suitable for the ANP service presented between the hours of 0800 and 2000, of which 54% attended between 0800 and 1600 h. Sunday emerged as the busiest day in July 2005 whereas Monday was found to be the busiest day in February 2006. Friday was found to be consistently busy for both months.

  16. Ocular-Motor Profile and Effects of Memantine in a Familial Form of Adult Cerebellar Ataxia with Slow Saccades and Square Wave Saccadic Intrusions: e69522

    National Research Council Canada - National Science Library

    Francesca Rosini; Pamela Federighi; Elena Pretegiani; Pietro Piu; R John Leigh; Alessandro Serra; Antonio Federico; Alessandra Rufa

    2013-01-01

    ...). We similarly tested two sisters, respectively of 58 and 60 years, with an unrecognized form of recessive, adult-onset cerebellar ataxia, peripheral neuropathy and slow saccades, who showed prominent...

  17. Ocular-motor profile and effects of memantine in a familial form of adult cerebellar ataxia with slow saccades and square wave saccadic intrusions

    National Research Council Canada - National Science Library

    Rosini, Francesca; Federighi, Pamela; Pretegiani, Elena; Piu, Pietro; Leigh, R John; Serra, Alessandro; Federico, Antonio; Rufa, Alessandra

    2013-01-01

    ...). We similarly tested two sisters, respectively of 58 and 60 years, with an unrecognized form of recessive, adult-onset cerebellar ataxia, peripheral neuropathy and slow saccades, who showed prominent...

  18. Teaching Elementary School Social Studies Methods under edTPA

    Science.gov (United States)

    An, Sohyun

    2016-01-01

    This article reports a self-study that analyzes my experience as a teacher educator navigating a turbulent educational landscape with the advent of edTPA. The data consist of my journal entries, the syllabi, handouts, work submitted by my students, and course evaluations. Data were analyzed by using an inductive process to describe how the edTPA…

  19. TechEdSat Nano-Satellite Series Fact Sheet

    Science.gov (United States)

    Murbach, Marcus; Martinez, Andres; Guarneros Luna, Ali

    2014-01-01

    TechEdSat-3p is the second generation in the TechEdSat-X series. The TechEdSat Series uses the CubeSat standards established by the California Polytechnic State University Cal Poly), San Luis Obispo. With typical blocks being constructed from 1-unit (1U 10x10x10 cm) increments, the TechEdSat-3p has a 3U volume with a 30 cm length. The project uniquely pairs advanced university students with NASA researchers in a rapid design-to-flight experience lasting 1-2 semesters.The TechEdSat Nano-Satellite Series provides a rapid platform for testing technologies for future NASA Earth and planetary missions, as well as providing students with an early exposure to flight hardware development and management.

  20. ED leadership competency matrix: an administrative management tool.

    Science.gov (United States)

    Propp, Douglas A; Glickman, Seth; Uehara, Dennis T

    2003-10-01

    A successful ED relies on its leaders to master and demonstrate core competencies to be effective in the many arenas in which they interact and are responsible. A unique matrix model for the assessment of an ED leadership's key administrative skill sets is presented. The model incorporates capabilities related to the individual's cognitive aptitude, experience, acquired technical skills, behavioral characteristics, as well as the ability to manage relationships effectively. Based on the personnel inventory using the matrix, focused evaluation, development, and recruitment of ED key leaders occurs. This dynamic tool has provided a unique perspective for the evaluation and enhancement of overall ED leadership performance. It is hoped that incorporation of such a model will similarly improve the accomplishments of EDs at other institutions.

  1. Torrefied Biomass Pellets—Comparing Grindability in Different Laboratory Mills

    Directory of Open Access Journals (Sweden)

    Jan Hari Arti Khalsa

    2016-10-01

    Full Text Available The firing and co-firing of biomass in pulverized coal fired power plants around the world is expected to increase in the coming years. Torrefaction may prove to be a suitable way of upgrading biomass for such an application. For transport and storage purposes, the torrefied biomass will tend to be in pellet form. Whilst standard methods for the assessment of the milling characteristics of coal exist, this is not the case for torrefied materials—whether in pellet form or not. The grindability of the fuel directly impacts the overall efficiency of the combustion process and as such it is an important parameter. In the present study, the grindability of different torrefied biomass pellets was tested in three different laboratory mill types; cutting mill (CM, hammer mill (HM and impact mill (IM. The specific grinding energy (SGE required for a defined mass throughput of pellets in each mill was measured and results were compared to other pellet characterization methods (e.g., durability, and hardness as well as the modified Hardgrove Index. Seven different torrefied biomass pellets including willow, pine, beech, poplar, spruce, forest residue and straw were used as feedstock. On average, the particle-size distribution width (across all feedstock was narrowest for the IM (0.41 mm, followed by the HM (0.51 mm and widest for the CM (0.62 mm. Regarding the SGE, the IM consumed on average 8.23 Wh/kg while CM and HM consumed 5.15 and 5.24 Wh/kg, respectively. From the three mills compared in this study, the IM seems better fit for being used in a standardized method that could be developed in the future, e.g., as an ISO standard.

  2. Responses of three-dimensional flow to variations in the angle of incident wind and profile form of dunes: Greenwich Dunes, Prince Edward Island, Canada

    Science.gov (United States)

    Walker, Ian J.; Hesp, Patrick A.; Davidson-Arnott, Robin G. D.; Bauer, Bernard O.; Namikas, Steven L.; Ollerhead, Jeff

    2009-04-01

    This study reports the responses of three-dimensional near-surface airflow over a vegetated foredune to variations in the conditions of incident flow during an 8-h experiment. Two parallel measurement transects were established on morphologically different dune profiles: i) a taller, concave-convex West foredune transect with 0.5-m high, densely vegetated (45%), seaward incipient foredune, and ii) a shorter, concave-straight East foredune transect with lower, sparsely vegetated (14%) seaward incipient foredune. Five stations on each transect from the incipient dune to the crest were equipped with ultrasonic anemometers at 0.6 and 1.65 m height and logged at 1 Hz. Incident conditions were recorded from a 4-m tower over a flat beach. Winds increased from 6 m s - 1 to > 20 m s - 1 and were generally obliquely onshore (ENE, 73°). Three sub-events and the population of 10-minute averages of key properties of flow ( U, W, S, CV U) from all sample locations on the East transect ( n = 235) are examined to identify location- and profile-specific responses over 52° of the incident direction of flow (from 11 to 63° onshore). Topographic steering and forcing cause major deviations in the properties and vectors of near-surface flow from the regional wind. Topographic forcing on the concave-straight dune profile increases wind speed and steadiness toward the crest, with speed-up values to 65% in the backshore. Wind speed and steadiness of flow are least responsive to changes in incident angle in the backshore because of stagnation of flow and are most responsive at the lower stoss under pronounced streamline compression. On the steeper concave-convex profile, speed and steadiness decrease toward the crest because of stagnation of flow at the toe and flow expansion at the slope inflection point on the lower stoss. Net downward vertical velocity occurs over both profiles, increases toward the crest, and reflects enhanced turbulent momentum conveyance toward the surface. All of

  3. Using Kentucky State Standards as Benchmarks: Quantifying Incoming Ed.S. Students' Knowledge as They Journey toward Principalship

    Science.gov (United States)

    Hearn, Jessica E.

    2015-01-01

    Principal preparation programs in Kentucky can use the items in the Dispositions, Dimensions, and Functions for School Leaders (EPSB, 2008) as mastery benchmarks to quantify incoming Educational Specialist (Ed.S) students' perceived level of mastery. This can serve both internal and external purposes by providing diagnostic feedback to students…

  4. Geographic Profiling: Knowledge Through Prediction

    Science.gov (United States)

    2014-06-01

    acts. In general, geographic profiling “is based on crime pattern, routine activity, and rational choice theories from environmental criminology , a...Information Systems and Crime Analysis , ed. Fahui Wang (Hershey, PA: Idea Group, 2005), 104. 3 models to the actual outcomes and determine the...order to construct a geographic profile, the coordinates of crime scenes are entered into a software analysis program that contains an algorithm known

  5. Experts: to crack down on violence in the ED, establish a robust system of reporting, educating staff.

    Science.gov (United States)

    2013-09-01

    Researchers say that most ED personnel will experience some form of physical or verbal violence at some point in their careers. However, when such incidents are regularly reported, the patients involved can be flagged in a hospital's computer system, making future events involving the same patients much less likely. Further, when ED personnel are alert to the clues that a patient or family member is becoming agitated, early intervention can usually prevent the situation from escalating to violence. About one-half of all ED personnel will experience a physical assault, and 97%-100% will experience verbal abuse during their careers, according to research. A first step in developing a strategy for dealing with violence is to educate ED personnel about what constitutes workplace violence so that all such incidents can be reported. Experts say many ED workers fail to recognize some instances of violence, based on the intent of the person involved. However, intent should not be a factor, they say. In many cases, empathy and good customer service skills can prevent tense situations from escalating to violence, but experts say that it is important to intervene at the first sign of agitation. ED administrators should gather input from frontline staff on how to most effectively derail instances of violence.

  6. Modelling the effects of dietary methionine level and form on postprandial plasma essential amino acid profiles in rainbow trout (Oncorhynchus mykiss)

    DEFF Research Database (Denmark)

    Rolland, Marine; Feekings, Jordan P.; Dalsgaard, Anne Johanne Tang

    2016-01-01

    essential amino acid (EAA) in rainbow trout. Twelve diets were formulated with pea and soya protein concentrate or fish meal as the main protein ingredients and were supplemented or not with increasing amount of either crystalline or agar-coated methionine. Fish were acclimatized to one of the 12 diets......Aquafeed formulation is susceptible to affect amino acid (AA) availability for metabolic functions. Statistical models were applied to quantify the effect of dietary methionine level (from 6.01 to 16.17 g kg 1 dry matter) and form (free, coated or bound) on postprandial concentrations of plasma...... for 6 weeks before postprandial plasma sampling (six sampling points up to 36 h, seven fish each time), further analysed for EAA content. Using generalized additive models, we show that (i) dietary methionine level and form explained 74% postprandial methionine plasma variations and that (ii...

  7. - ED ITO RIAL - A Century's Perspective

    African Journals Online (AJOL)

    2. conscIOusness. The Union Defence Force, an essentially unhappy marriage between the British and. Boer military systems, was formed in July 1912 as a result of this war. A Defence Council, largely ineffective, was appointed to deal with conflict. The UDF, had to face two Afrikaner rebellions - one in 1914 and another ...

  8. Impact of glucocorticoid receptor gene polymorphisms on the metabolic profile of adult patients with the classical form of 21-hydroxylase deficiency.

    Directory of Open Access Journals (Sweden)

    Ricardo P P Moreira

    Full Text Available BACKGROUND: CAH patients have an increased risk of cardiovascular disease, and it remains unknown if lifelong glucocorticoid (GC treatment is a contributing factor. In the general population, glucocorticoid receptor gene (NR3C1 polymorphisms are associated with an adverse metabolic profile. Our aim was to analyze the association between the NR3C1 polymorphisms and the metabolic profile of CAH patients. METHODOLOGY: Sixty-eight adult patients (34SV/34SW with a mean age of 28.4±9 years received dexamethasone (mean 0.27±0.11 mg/day to obtain normal androgen levels. SW patients also received fludrocortisone (50 µg/day. Metabolic syndrome (MetS was defined by the NCEP ATPIII criteria and obesity by BMI ≥30 kg/m². NR3C1 alleles were genotyped, and association analyses with phenotype were carried out with Chi-square, t-test and regression analysis. RESULTS: Obesity and MetS were observed in 23.5% and 7.3% of patients, respectively, and were not correlated with GC doses and treatment duration. BMI was positively correlated with blood pressure (BP, triglycerides (TG, LDL-c levels and HOMA-IR and inversely correlated with HDL-c levels. BclI and A3669G variants were found in 26.4% and 9.6% of alleles, respectively. Heterozygotes for the BclI polymorphism presented with higher BMI (29 kg/m²±5.3 vs. 26 kg/m²±5.3, respectively and waist circumference (89 cm±12.7 vs. 81 cm±13, respectively compared to wild-type subjects. Hypertension was found in 12% of patients and heterozygotes for the BclI polymorphism presented higher systolic BP than wild type subjects. Low HDL-c and high TG levels were identified in 30% and 10% of patients, respectively, and were not associated with the NR3C1 polymorphisms. A3669G carriers and non-carriers did not differ. CONCLUSION: In addition to GC therapy, the BclI GR variant might play an important role in obesity susceptibility in CAH patients. Genotyping of GR polymorphisms could result in the identification of a

  9. Impact of Glucocorticoid Receptor Gene Polymorphisms on the Metabolic Profile of Adult Patients with the Classical Form of 21-Hydroxylase Deficiency

    Science.gov (United States)

    Moreira, Ricardo P. P.; Gomes, Larissa G.; Mendonca, Berenice B.; Bachega, Tânia A. S. S.

    2012-01-01

    Background CAH patients have an increased risk of cardiovascular disease, and it remains unknown if lifelong glucocorticoid (GC) treatment is a contributing factor. In the general population, glucocorticoid receptor gene (NR3C1) polymorphisms are associated with an adverse metabolic profile. Our aim was to analyze the association between the NR3C1 polymorphisms and the metabolic profile of CAH patients. Methodology Sixty-eight adult patients (34SV/34SW) with a mean age of 28.4±9 years received dexamethasone (mean 0.27±0.11 mg/day) to obtain normal androgen levels. SW patients also received fludrocortisone (50 µg/day). Metabolic syndrome (MetS) was defined by the NCEP ATPIII criteria and obesity by BMI ≥30 kg/m2. NR3C1 alleles were genotyped, and association analyses with phenotype were carried out with Chi-square, t-test and regression analysis. Results Obesity and MetS were observed in 23.5% and 7.3% of patients, respectively, and were not correlated with GC doses and treatment duration. BMI was positively correlated with blood pressure (BP), triglycerides (TG), LDL-c levels and HOMA-IR and inversely correlated with HDL-c levels. BclI and A3669G variants were found in 26.4% and 9.6% of alleles, respectively. Heterozygotes for the BclI polymorphism presented with higher BMI (29 kg/m2±5.3 vs. 26 kg/m2±5.3, respectively) and waist circumference (89 cm±12.7 vs. 81 cm±13, respectively) compared to wild-type subjects. Hypertension was found in 12% of patients and heterozygotes for the BclI polymorphism presented higher systolic BP than wild type subjects. Low HDL-c and high TG levels were identified in 30% and 10% of patients, respectively, and were not associated with the NR3C1 polymorphisms. A3669G carriers and non-carriers did not differ. Conclusion In addition to GC therapy, the BclI GR variant might play an important role in obesity susceptibility in CAH patients. Genotyping of GR polymorphisms could result in the identification of a subgroup at risk

  10. The epidemiology of assault-related hospital in-patient admissions and ED attendances.

    LENUS (Irish Health Repository)

    O'Farrell, A

    2013-03-01

    The aim of this study was to describe the epidemiology and impact of serious assault warranting in-patient care over six years and its impact on ED attendances in a large teaching hospital in Dublin over 2 years. There were 16,079 emergency assault-related inpatient hospital discharges reducing from 60.1 per 100,000 population in 2005 to 50.6 per 100,000 population in 2010. The median length of stay was 1 day (1-466) representing 49,870 bed days. The majority were young males (13,921, 86.6%; median age 26 years). Overall crime figures showed a similar reduction. However, knife crimes did not reduce over this period. Data on ED attendances confirmed the age and gender profile and also showed an increase at weekends. Alcohol misuse was recorded in 2,292\\/16079 (14%) of in-patient cases and 242\\/2484 (10%) in ED attendances. An inter-sectoral preventative approach specifically targeting knife crime is required to reduce this burden on health services.

  11. lsnjbhakta@gmail.com A Comparative SEM-EDS Elemental ...

    African Journals Online (AJOL)

    Michael Horsfall

    X25) and microscopic. (X5000) pictures of the mud exhibited a wide range of shapes and surface texture for individual particle. Elemental criteria: EDS analysis showed the clear distribution criteria of ten elements, Carbon,. Phosphorous,. Sulfur ...

  12. Erectile Dysfunction Herbs: A Natural Treatment for ED?

    Science.gov (United States)

    ... erectile dysfunction: A natural treatment for ED? Some herbs claim to help erectile dysfunction. Find out the ... You've likely seen advertisements for erectile dysfunction herbs or supplements to "increase your sexual performance." Could ...

  13. Review: Gravers, Mikael (ed. (2007, Exploring Ethnic Diversity in Burma

    Directory of Open Access Journals (Sweden)

    Roland Mischung

    2009-01-01

    Full Text Available Review of the edited volume: Gravers, Mikael (ed., Exploring Ethnic Diversity in Burma, Copenhagen: NIAS Press (= NIAS Studies in Asian Topics Series, 39, 2007, ISBN 9788791114960, 283 pages

  14. Elementi ed esercizi di geometria analitica e proiettiva

    CERN Document Server

    Francia, Giovanni

    1950-01-01

    La retta : preliminario ; coordinate cartesiane nel piano, equazioni della retta, distanze ed angoli ; cambiamento delle coordinate, coordinate polari ; il cerchio ; le coniche come luoghi geometrici : l'ellisse, l'iperbole, parabola.

  15. Structure of catalase determined by MicroED

    Science.gov (United States)

    Nannenga, Brent L; Shi, Dan; Hattne, Johan; Reyes, Francis E; Gonen, Tamir

    2014-01-01

    MicroED is a recently developed method that uses electron diffraction for structure determination from very small three-dimensional crystals of biological material. Previously we used a series of still diffraction patterns to determine the structure of lysozyme at 2.9 Å resolution with MicroED (Shi et al., 2013). Here we present the structure of bovine liver catalase determined from a single crystal at 3.2 Å resolution by MicroED. The data were collected by continuous rotation of the sample under constant exposure and were processed and refined using standard programs for X-ray crystallography. The ability of MicroED to determine the structure of bovine liver catalase, a protein that has long resisted atomic analysis by traditional electron crystallography, demonstrates the potential of this method for structure determination. DOI: http://dx.doi.org/10.7554/eLife.03600.001 PMID:25303172

  16. Nuclear Medicine Physics: The Basics. 7th ed.

    Science.gov (United States)

    Mihailidis, Dimitris

    2012-10-01

    Nuclear Medicine Physics: The Basics. 7th ed. Ramesh Chandra, Lippincott Williams and Wilkins, a Wolters Kluwer Business. Philadelphia, 2012. Softbound, 224 pp. Price: $69.99. ISBN: 9781451109412. © 2012 American Association of Physicists in Medicine.

  17. Collaborative form(s)

    DEFF Research Database (Denmark)

    Gunn, Wendy

    Gunn asks us to consider beauty as collaborative forms of action generated by moving between design by means of anthropology and anthropology by means of design. Specifically, she gives focus to play-like reflexions on practices of designing energy products, systems and infrastructure. Design...... anthropology engages groups of people within collaborative, interdisciplinary, inter-organizational design processes and co-analytic activities vs. the individual anthropologist conducting studies of people. In doing anthropology by means of design as Gatt and Ingold (2013) have shown, design is considered...

  18. Ocular-motor profile and effects of memantine in a familial form of adult cerebellar ataxia with slow saccades and square wave saccadic intrusions.

    Directory of Open Access Journals (Sweden)

    Francesca Rosini

    Full Text Available Fixation instability due to saccadic intrusions is a feature of autosomal recessive spinocerebellar ataxias, and includes square wave intrusions (SWI and macrosaccadic oscillations (MSO. A recent report suggested that the non-competitive antagonist of NMDA receptors, memantine, could decrease MSO and improve fixation in patients with spinocerebellar ataxia with saccadic intrusions (SCASI. We similarly tested two sisters, respectively of 58 and 60 years, with an unrecognized form of recessive, adult-onset cerebellar ataxia, peripheral neuropathy and slow saccades, who showed prominent SWI and also complained with difficulty in reading. We tested horizontal visually guided saccades (10°-18° and three minutes of steady fixation in each patient and in thirty healthy controls. Both patients showed a significant reduction of peak and mean velocity compared with control subjects. Large SWI interrupting steady fixation were prominent during steady fixation and especially following visually guided saccades. Eye movements were recorded before and during the treatment with memantine, 20 mg/daily for 6 months. The treatment with memantine reduced both the magnitude and frequency of SWI (the former significantly, but did not modified neurological conditions or saccade parameters. Thus, our report suggests that memantine may have some general suppressive effect on saccadic intrusions, including both SWI and MSO, thereby restoring the capacity of reading and visual attention in these and in other recessive forms of ataxia, including Friedreich's, in which saccadic intrusions are prominent.

  19. Ocular-motor profile and effects of memantine in a familial form of adult cerebellar ataxia with slow saccades and square wave saccadic intrusions.

    Science.gov (United States)

    Rosini, Francesca; Federighi, Pamela; Pretegiani, Elena; Piu, Pietro; Leigh, R John; Serra, Alessandro; Federico, Antonio; Rufa, Alessandra

    2013-01-01

    Fixation instability due to saccadic intrusions is a feature of autosomal recessive spinocerebellar ataxias, and includes square wave intrusions (SWI) and macrosaccadic oscillations (MSO). A recent report suggested that the non-competitive antagonist of NMDA receptors, memantine, could decrease MSO and improve fixation in patients with spinocerebellar ataxia with saccadic intrusions (SCASI). We similarly tested two sisters, respectively of 58 and 60 years, with an unrecognized form of recessive, adult-onset cerebellar ataxia, peripheral neuropathy and slow saccades, who showed prominent SWI and also complained with difficulty in reading. We tested horizontal visually guided saccades (10°-18°) and three minutes of steady fixation in each patient and in thirty healthy controls. Both patients showed a significant reduction of peak and mean velocity compared with control subjects. Large SWI interrupting steady fixation were prominent during steady fixation and especially following visually guided saccades. Eye movements were recorded before and during the treatment with memantine, 20 mg/daily for 6 months. The treatment with memantine reduced both the magnitude and frequency of SWI (the former significantly), but did not modified neurological conditions or saccade parameters. Thus, our report suggests that memantine may have some general suppressive effect on saccadic intrusions, including both SWI and MSO, thereby restoring the capacity of reading and visual attention in these and in other recessive forms of ataxia, including Friedreich's, in which saccadic intrusions are prominent.

  20. The 20kDa and 22kDa forms of human growth hormone (hGH) exhibit different intracellular signalling profiles and properties.

    Science.gov (United States)

    Yao-Xia, Liu; Jing-Yan, Chen; Xia-Lian, Tang; Ping, Chen; Min, Zhang

    2017-07-01

    Human Growth Hormone (hGH) includes two main variants. The first is 22kDa GH (22K-GH), which is predominant in the blood circulation. The second most abundant variant is 20K-GH, which makes up 5-10% of the blood circulation. Both bind and activate the same receptor, called the human growth hormone receptor (GHR). However, the reason why 22K-GH and 20K-GH exhibit similar, but not identical physiological activities remains poorly understood. In this article, the intracellular signalling profiles between these two hormones were examined. Western blot analyses were performed in 3T3-F442A and CHO cells transfected with GHR (CHO-GHR). The results revealed that both 22K-GH and 20K-GH can activate Janus kinase 2 (JAK2) and signal transducers and activators of transcription 1, 3 and 5 (STATs 1/3/5). Both induced tyrosine phosphorylation of JAK2 and STAT/1/3/5 in a time-dependent and dose-dependent manner. However, there were significant differences in the intracellular signalling properties between 22K-GH and 20K-GH. In particular, the kinetics of signalling shown by 22K-GH and 20K-GH is different. In addition, we found that the 20K-GH-induced tyrosine phosphorylation of signalling proteins was weaker than that of 22K-GH. Together, these observations indicate that the levels and kinetics of phosphorylation mediated by the main signalling proteins triggered by 22K-GH or 20K-GH were not exactly the same. This may provide a possible explanation for the different biological activities exhibited by 22K-GH and 20K-GH. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. Implicazioni cliniche ed economiche di tramadolo SR

    Directory of Open Access Journals (Sweden)

    Lorenzo Pradelli

    2004-12-01

    Full Text Available Tramadol is one of the preferred weak opioid agonists in the management of chronic pain, due to a good efficacy and safety profile, to a particularly low interference with cardiovascular and respiratory functions and a low dependence and abuse potential. The successful use of tramadol, nevertheless, is often limited by low patient compliance, a consequence of gastrointestinal side effects (mainly nausea and vomiting and frequent dosing regimens, among other reasons. In this paper, clinical studies conducted on slow-release formulations of tramadol and other strategies for compliance improvement in various pain conditions are reviewed. From the examined literature, it appears that the strategy with the best compliance is the use of slow release (SR formulations, which simplify dosing regimens and tend to have a somewhat better tolerability, and a slow dose escalation, which improves tolerability. The advantages of SR formulations have to be weighed against the superior acquisition cost and the slower onset of analgesia. A frame for the evaluation of the clinical and economical advantages and disadvantages of SR versus immediate release formulations of tramadol is also proposed.

  2. The Pathogenesis of the Demyelinating Form of Guillain-Barre Syndrome (GBS): Proteo-peptidomic and Immunological Profiling of Physiological Fluids*

    Science.gov (United States)

    Ziganshin, Rustam H.; Ivanova, Olga M.; Lomakin, Yakov A.; Belogurov, Alexey A.; Kovalchuk, Sergey I.; Azarkin, Igor V.; Arapidi, Georgij P.; Anikanov, Nikolay A.; Shender, Victoria O.; Piradov, Mikhail A.; Suponeva, Natalia A.; Vorobyeva, Anna A.; Gabibov, Alexander G.; Ivanov, Vadim T.; Govorun, Vadim M.

    2016-01-01

    Acute inflammatory demyelinating polyneuropathy (AIDP) - the main form of Guillain-Barre syndrome—is a rare and severe disorder of the peripheral nervous system with an unknown etiology. One of the hallmarks of the AIDP pathogenesis is a significantly elevated cerebrospinal fluid (CSF) protein level. In this paper CSF peptidome and proteome in AIDP were analyzed and compared with multiple sclerosis and control patients. A total protein concentration increase was shown to be because of even changes in all proteins rather than some specific response, supporting the hypothesis of protein leakage from blood through the blood-nerve barrier. The elevated CSF protein level in AIDP was complemented by activization of protein degradation and much higher peptidome diversity. Because of the studies of the acute motor axonal form, Guillain-Barre syndrome as a whole is thought to be associated with autoimmune response against neurospecific molecules. Thus, in AIDP, autoantibodies against cell adhesion proteins localized at Ranvier's nodes were suggested as possible targets in AIDP. Indeed, AIDP CSF peptidome analysis revealed cell adhesion proteins degradation, however no reliable dependence on the corresponding autoantibodies levels was found. Proteome analysis revealed overrepresentation of Gene Ontology groups related to responses to bacteria and virus infections, which were earlier suggested as possible AIDP triggers. Immunoglobulin blood serum analysis against most common neuronal viruses did not reveal any specific pathogen; however, AIDP patients were more immunopositive in average and often had polyinfections. Cytokine analysis of both AIDP CSF and blood did not show a systemic adaptive immune response or general inflammation, whereas innate immunity cytokines were up-regulated. To supplement the widely-accepted though still unproven autoimmunity-based AIDP mechanism we propose a hypothesis of the primary peripheral nervous system damaging initiated as an innate

  3. Normal radiographic findings. 4. act. ed.; Roentgennormalbefunde

    Energy Technology Data Exchange (ETDEWEB)

    Moeller, T.B. [Gemeinschaftspraxis fuer Radiologie und Nuklearmedizin, Dillingen (Germany)

    2003-07-01

    This book can serve the reader in three ways: First, it presents normal findings for all radiographic techniques including KM. Important data which are criteria of normal findings are indicated directly in the pictures and are also explained in full text and in summary form. Secondly, it teaches the systematics of interpreting a picture - how to look at it, what structures to regard in what order, and for what to look in particular. Checklists are presented in each case. Thirdly, findings are formulated in accordance with the image analysis procedure. All criteria of normal findings are defined in these formulations, which make them an important didactic element. (orig.)

  4. Smad1-Smad5 ovarian conditional knockout mice develop a disease profile similar to the juvenile form of human granulosa cell tumors.

    Science.gov (United States)

    Middlebrook, Brooke S; Eldin, Karen; Li, Xiaohui; Shivasankaran, Sujatha; Pangas, Stephanie A

    2009-12-01

    Granulosa cell tumors (GCTs) of the ovary are rare sex cord stromal tumors. Although generally indolent, GCTs recur, and if not diagnosed and treated in early stages, survival rates are significantly shortened. Very little is known regarding GCT etiology. Because of the low incidence of cases and lack of standard diagnostics, mouse models for granulosa cell tumors are a valuable tool for studying GCTs and provide models for developing diagnostic and treatment strategies. We recently developed a novel mouse model of metastatic granulosa cell tumors by genetic deletion of the bone morphogenetic protein signaling transcription factors (SMADs) in granulosa cells of the ovary. Histological and serum hormone analyses reveal that this mouse model most closely resembles the juvenile form of GCT. We further analyzed samples of human juvenile GCT (JGCT) for expression of anti-Müllerian hormone and activation of two major signaling pathways: TGFbeta/SMAD2/3 and wingless-related mouse mammary tumor virus integration site (Wnt)/beta-catenin. The TGFbeta family is active in mouse Smad1-Smad5 double knockout tumors, and here we show that this pathway, but not the beta-catenin pathway, is activated in samples of human JGCT. These data suggest that the SMAD family, possibly through disruption of SMAD1/5 or activation of SMAD2/3 may contribute to the pathogenesis of JGCT in humans.

  5. Environmental law. 2. rev. ed.; Umweltrecht

    Energy Technology Data Exchange (ETDEWEB)

    Meyerholt, Ulrich

    2007-07-01

    The author of the book under consideration describes the environment law in a well readable and systematic form. By means of this book the reader is to be able to understand and arrange environmental-legal questions. The book consists of the following sections: (a) Denotation of the environment law; (b) Fundamentals of the legal order and the application of law; (c) Environmental constitutional law; (d) Principles of the environment law; (e) Instruments in the environment law; (f) Environmental private law; (g) Environmental criminal law; (h) Legal protection questions in the public environment law; (i) Environmental European right; (j) Environmental international law; (k) Pollution control law; (l) Water legislation; (m)Soil conservation law; (n) Recycling law and waste management law; (o) Nature conservation law; (p) Law of hazardous materials.

  6. Ambienti Circumstellari ed Interstellari di Supernovae di vario Tipo ed Applicazioni Astrofisiche

    Science.gov (United States)

    Boffi, Francesca R.

    Nella presente tesi vengono studiati gli ambienti circumstellari ed interstellari di supernovae (anche SNe; singolare SN) di vario tipo. In particolare si descrivono alcune applicazioni astrofisiche, relative a questi ambienti, che permettono di desumere informazioni sui sistemi stellari progenitori delle supernovae o di determinare le distanze a tali oggetti. L' emissione radio da supernovae, prodotta nell' ambiente circumstellare ad opera dell'interazione idrodinamica del gas di SN con l' ambiente circostante, puo' essere impiegata come mezzo di indagine del sistema di pre-supernova. In particolare si e' introdotta l'idea che tale emissione possa essere impiegata nel caso delle SNe di tipo Ia come test dei sistemi progenitori di tipo simbiotico. Il test e' stato effettuato sulla SN 1986G, per la quale avevamo ottenuto limiti superiori a lunghezze d'onda radio. Nel caso che un sistema simbiotico sia responsabile di una SN Ia, l'interazione tra l' ejecta e una shell circumstellare origina, in un'epoca molto prossima al massimo di luce, un'emissione radio rivelabile con strumenti tipo Very Large Array. Inoltre l'emissione radio fornisce informazioni circa gli stadi di pre-supernova nel caso di altri tipi di supernova. In questo lavoro di tesi vengono presentati i risultati ottenuti nel caso delle SNe di tipo II 1984E e 1986E. Queste due SNe non mostrano emissione radio: la prima, in prossimita del massimo ottico, stava interagendo con una shell circumstellare prodotta da un episodio di perdita di massa di breve durata in fase di pre-supernova; la seconda, invece e' la prima SN ``vecchia'' ad essere rivelata nell' ottico ma non nel radio (l' oggetto non ha ancora iniziato la fase di supernova remnant ed emette radiazione ottica prodotta ancora per interazione circumstellare). In ambiente circum-interstellare, gli echi di luce, prodotti dallo scattering della luce della supernova ad opera della polvere presente, possono essere utilizzati per determinare le distanze

  7. Patient anxiety may influence the efficacy of ED pain management.

    Science.gov (United States)

    Craven, Philip; Cinar, Orhan; Madsen, Troy

    2013-02-01

    The aim of this study was to evaluate the incidence of anxiety and rates of anxiety treatment in emergency department (ED) patients presenting with pain-related complaints. We prospectively evaluated patients in an urban academic tertiary care hospital ED from 2000 through 2010. We enrolled a convenience sample of adult patients presenting with pain and recorded patient complaint, medication administration, satisfaction, and pain and anxiety scores throughout their stay. We stratified patients into 4 different groups according to anxiety score at presentation (0, none; 1-4, mild; 5-7, moderate; 8-10, severe). We enrolled 10 664 ED patients presenting with pain-related complaints. Patients reporting anxiety were as follows: 25.7%, none; 26.1%, mild; 23.7%, moderate; and 24.5%, severe. Although 48% of patients described moderate to severe anxiety at ED presentation and 60% were willing to take a medication for anxiety, only 1% received anxiety treatment. Thirty-five percent of patients still reported moderate/severe anxiety at discharge. Severe anxiety at ED presentation was associated with increased demand for pain medication (odds ratio [OR], 1.40; 95% confidence interval [CI], 1.10-1.79) and anxiety medication (OR, 4.34; 95% CI, 3.68-5.11) during the ED stay and decreased satisfaction with the treatment of pain (β coefficient = -0.328; P < .001). After adjusting for age, sex, and presentation pain scores, patients who reported severe anxiety were more likely to receive an analgesic (OR, 1.33; 95% CI, 1.19-1.50) and an opioid (OR, 1.25; 95% CI, 1.11-1.41) during the ED stay. Anxiety may be underrecognized and undertreated in patients presenting with pain-related complaints. Patients reporting severe anxiety were less likely to report satisfaction with the treatment of their pain, despite higher rates of analgesic administration. Copyright © 2013 Elsevier Inc. All rights reserved.

  8. MANY MEN USED ED TREATMENT WITHOUT THEIR PARTNERS’ KNOWLEDGE

    Directory of Open Access Journals (Sweden)

    Tan HM

    2007-01-01

    Full Text Available This paper aimed to identify and explore the understanding and perception of erectile dysfunction (ED using exploratory qualitative approaches. This study was conducted in Klang Valley, Malaysia. Purposive sampling was used to recruit 17 urban men aged 40-75 years. A semi-structural interview guide was used to explore men’s understanding of ED, impacts on their well-being and experiences with treatments. The focus groups revealed that ED was perceived to be an important loss in men’s lives as sexual performance was closely related to manhood. The men associated ED with a loss of masculinity and self-esteem. Men’s understanding of ED treatments was restricted to phophodiesterase type 5 inhibitors (PDE-5 inhibitors and traditional therapies. Although PDE-5 inhibitors were perceived to be effective, they were concerned about their safety and costs. Some of the men have learned to cope with ED rather than to seek help, particularly among older men, who attributed their decreased sexual capacities and erection difficulties to aging, and therefore conditioned themselves to accepting it. In contrast, younger men who have erectile difficulties are considered as ‘abnormal’, and are more likely to seek help and receive treatment for their sexual problem. Men’s knowledge of and experience with modern treatments of ED were mainly associated with PDE-5 inhibitors. Their perception towards PDE-5 inhibitors was largely influenced by personal experience, information from mass media and friends. The high cost and fear of side effects were two main deterrents in the use of PDE-5 inhibitors. Many men had conceded their use of PDE-5 inhibitors without their partners’ knowledge. They worried that their partners would view the matter with suspicion and mistrust.

  9. Profilo clinico ed economico di oxatomide

    Directory of Open Access Journals (Sweden)

    Lorenzo Pradelli

    2003-12-01

    Full Text Available Oxatomide is an antiallergic drug with a double mechanism of action: it possesses antagonistic activity on the H1 histaminergic receptor and it inhibits the production and release of flogistic and allergic mediators by effector cells, presumably acting as a selective calcium channel blocker on these cellular types. The efficacy and safety of oxatomide have been evaluated in many studies conducted on patients affected by different clinical conditions, demonstrating remarkable flexibility. It proved to be safe and effective also in extreme ages, i.e. children under 3 months of age and elderly over 80 years. Approved indications include rhinitis, asthma, conjunctivitis, urticaria, atopic and allergic dermatitis and food allergy and intolerance. In direct comparisons, oxatomide consistently proved superior than placebo and equally or more effective than other consolidated antiallergics. The drug tolerability is good, its main side effects are drowsiness and weight gain, usually transient. Cardiac and hepatic safety data are very reassuring, as is the case for drug interaction potential. Form an economical point of view, the drug acquisition cost is acceptable, being among the lowest in its class, at equally effective doses. Overall, the efficacy in several clinical conditions, the good tolerability in most patients and the reasonable purchase cost suggest that oxatomide is characterized by excellent risk-to-benefit and cost-to-benefit ratios in the treatment of allergic pathologies.

  10. Automated SEM-EDS GSR Analysis for Turkish Ammunitions

    Science.gov (United States)

    Cakir, Ismail; Uner, H. Bulent

    2007-04-01

    In this work, Automated Scanning Electron Microscopy with Energy Dispersive X-ray Spectrometry (SEM-EDS) was used to characterize 7.65 and 9mm cartridges Turkish ammunition. All samples were analyzed in a SEM Jeol JSM-5600LV equipped BSE detector and a Link ISIS 300 (EDS). A working distance of 20mm, an accelerating voltage of 20 keV and gunshot residue software was used in all analysis. Automated search resulted in a high number of particles analyzed containing gunshot residues (GSR) unique elements (PbBaSb). The obtained data about the definition of characteristic GSR particles was concordant with other studies on this topic.

  11. New psych unit eases patient burden in ED.

    Science.gov (United States)

    2008-06-01

    Creating a special unit for psychiatric patients frees up beds in your ED, ensures better care for that patient population, and improves the atmosphere in the main department for the rest of your patients. Consider these suggestions: The creation of a psych unit can be extremely costly. Be prepared to demonstrate projected savings when pitching the idea to administration. Make sure an ED physician has overall responsibility for each patient at all times. Keep a regular group of nurses in rotation. This setup will help ensure smooth handoffs.

  12. Structural and compositional properties of CZTS thin films formed by rapid thermal annealing of electrodeposited layers

    Science.gov (United States)

    Lehner, J.; Ganchev, M.; Loorits, M.; Revathi, N.; Raadik, T.; Raudoja, J.; Grossberg, M.; Mellikov, E.; Volobujeva, O.

    2013-10-01

    In this work Cu2ZnSnS4 (CZTS) thin films were formed by rapid thermal annealing (RTA) of sequentially electrodeposited Cu-Zn and Sn films in 5% H2S containing atmosphere. Six different thermal profiles were used in the experiments. In three of these, the temperature ramping up was varied, while the variable in the other three profiles was the cooling down rate. The optimising parameters for RTA of electrodeposited films were found and annealed films were characterised by X-ray diffraction (XRD), micro-Raman spectroscopy, scanning electron microscopy and energy dispersive X-ray spectroscopy (SEM+EDS). The material parameters such as lattice strain and crystallite size were also determined and the influence of annealing temperature and heating rate on these parameters was discussed.The pathway of MoS2 formation was investigated.

  13. Structural requirements for the interaction between peptide antigens and I-Ed molecules

    DEFF Research Database (Denmark)

    Sette, A; Adorini, L; Appella, E

    1989-01-01

    amino acid substitution analogues of one good I-Ed binder, hen egg lysozyme 107-116, were analyzed for their capacity to bind to I-Ed molecules and to activate two different I-Ed-restricted T cell hybridomas. The results illustrate the great permissiveness of I-Ed-peptide interaction and the great......We have analyzed the structural characteristics of the interaction between I-Ed molecules and their peptide ligands. It was found that unrelated good I-Ed binders share structurally similar "core" regions that were experimentally demonstrated to be crucial for binding to I-Ed molecules. Single...

  14. Psychological and psychopathological variables associated with eating disorders (ED

    Directory of Open Access Journals (Sweden)

    Antonio Fernández-Delgado

    2016-07-01

    Full Text Available Objective: The aim of this study was to compare some psychological and psychopathological variables usually associated with different types of patients with eating disorders (ED. A total of 22 variables (psychological, psychopathological and specifically related to TCA were analyzed in three groups of patients with anorexia nervosa (AN, bulimia nervosa (BN and eating disorders not otherwise specified (EDNOS. Method: The sample consisted of 76 patients diagnosed with ED (mean age 20.13 ± 6.28 years; 69 women and 7 men. The following questionnaires were administered: Rosenberg's Self-Esteem Scale (SES, Symptom Checklist-90-Revised (SCL-90-R, Beck's Depression Inventory (BDI, State-Trait Anxiety Inventory (STAI, Body Shape Questionnaire (BSQ, Body Appreciation Scale (BAS, Eating Disorder Inventory-2 (EDI-2 and Body Image Quality of Life Inventory (BIQLI-SP. Results: Generally no significant differences between groups, except for the variables related to the BSQ and EDI-2 questionnaires, were found. The study of the correlations among the different variables specifically related to eating disorders and others, showed differences between groups. Conclusions: The present study shows few differences with respect to psychopathological symptoms among the different types of ED. Bearing in mind future studies, it would be interesting to use a bigger sample size, to include more men, and to distinguish between restricted/purging types of ED.

  15. Diagnostic utility of the genital Gram stain in ED patients.

    Science.gov (United States)

    Stefanski, Peter; Hafner, John W; Riley, Shanda L; Sunga, Kharmene L Y; Schaefer, Timothy J

    2010-01-01

    The study aimed to determine the diagnostic usefulness of the genital Gram stain in an emergency department (ED) population. A linked-query of an urban, tertiary-care, university- affiliated hospital laboratory database was conducted for all completed Chlamydia trachomatis and Neisseria gonorrhoeae DNA probes, Trichomonas vaginalis wet preps, and genital Gram stains performed on ED patient visits between January and December 2004. Positive criteria for a Gram stain included greater than 10 white blood cells per high-power field, gram-negative intracellular/extracellular diplococci (suggesting N gonorrhoeae), clue cells (suggesting T vaginalis), or direct visualization of T vaginalis organisms. DNA probes were used as the gold standard definition for N gonorrhoeae and C trachomatis infection. Of 1511 initially eligible ED visits, 941 were analyzed (genital Gram stain and DNA probe results both present), with a prevalence of either C trachomatis or N gonorrhoeae of 11.4%. A positive genital Gram stain was 75.7% sensitive and 43.3% specific in diagnosing either C trachomatis and/or N gonorrhoeae infection, and 80.4% sensitive and 32.2% specific when the positive cutoff was lowered to more than 5 white blood cells/high-power field. No Gram stains were positive for T vaginalis (with 47 positive wet mounts), and clue cells were noted on 117 Gram stains (11.6%). Gram stains in isolation lack sufficient diagnostic ability to detect either C trachomatis or N gonorrhoeae infection in the ED.

  16. I>Lo specchio frammentato ed il pagliaccio piangente : alienation ...

    African Journals Online (AJOL)

    Quest'articolo esamina il modo in cui il cinema di Nanni Moretti usa uno sguardo autoriflessivamente critico per parlare della condizione frammentata ed alienata di un soggetto maschile, italiano e di sinistra, nella tarda età capitalista. L'articolo mette a fuoco come l'uso morettiano dell' umorismo, con palesi tratti ...

  17. Mai alguses linastub dokfilm "Sinimäed" / Andris Feldmanis

    Index Scriptorium Estoniae

    Feldmanis, Andris, 1982-

    2006-01-01

    Valminud on 6-osalise ajaloodokumentaalide sarja "Kuum külm sõda" teine film "Sinimäed" : stsenaristid Kiur Aarma, Mart Laar, Eerik-Niiles Kross, Raimo Jõerand : režissöör Raimo Jõerand : Ruut Pictures

  18. Creating a Minnesota Statewide SNAP-Ed Program Evaluation

    Science.gov (United States)

    Gold, Abby; Barno, Trina Adler; Sherman, Shelley; Lovett, Kathleen; Hurtado, G. Ali

    2013-01-01

    Systematic evaluation is an essential tool for understanding program effectiveness. This article describes the pilot test of a statewide evaluation tool for the Supplemental Nutrition Assistance Program-Education (SNAP-Ed). A computer algorithm helped Community Nutrition Educators (CNEs) build surveys specific to their varied educational settings…

  19. Murray Pittock, ed., The Edinburgh Companion to Scottish Romanticism.

    Directory of Open Access Journals (Sweden)

    Manfred Malzahn

    2013-10-01

    Full Text Available Murray Pittock, ed., The Edinburgh Companion to Scottish Romanticism. Edinburgh: Edinburgh University Press, 2011. Pp. 251. ISBN 978-0-7486-3845-1 (hardback. £ 65.00. ISBN 978-0-7486-3846-8 (paperback. £ 21.99.

  20. Impact of Physician Navigators on productivity indicators in the ED.

    Science.gov (United States)

    Leung, Alexander K; Puri, Gaurav; Chen, Bingshu E; Gong, Zhenxian; Chan, Eddie; Feng, Edward; Duic, Marko

    2018-01-01

    We created Physician Navigators in our ED to help improve emergency physician (EP) productivity. We aimed to quantify the effect of Physician Navigators on measures of EP productivity: patient seen per hour (Pt/hr), and turn-around time (TAT) to discharge. Secondary objectives included examining their impact on measures of ED throughput for non-resuscitative patients: ED length of stay (LOS), door-to-physician time and left-without-being-seen rates (LWBS). In this retrospective study, 6845 clinical shifts worked by 20 EPs at a community ED in Newmarket, Canada from 1 January 2012 to 31 March 2015 were evaluated. Using a clustered design, we compared productivity measures between shifts with and without Physician Navigators, by physician. We used a linear mixed model to examine mean changes in Pt/hr and TAT to discharge for EPs who employed Physician Navigators. For secondary objectives, autoregressive modelling was performed to compare ED throughput metrics before and after the implementation of Physician Navigators for non-resuscitative patients. Patient volumes increased by 20 patients per day (p<0.001). Mean Pt/hr increased by 1.07 patients per hour (0.98 to 1.16, p<0.001). The mean TAT to discharge decreased by 10.6 min (-13.2 to -8.0, p<0.001). After implementation of the Physician Navigator programme, overall mean LOS for non-resuscitative patients decreased by 2.6 min (p=0.007), and mean door-to-physician time decreased by 7.4 min (p<0.001). LBWS rates decreased from 1.13% to 0.63% of daily patient volume (p<0.001). Despite an ED volume increase, the use of a Physician Navigator was associated with significant improvements in EP productivity, and significant reductions in ED throughput times. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  1. Comparative Analgesic Efficacy of Oxycodone/Acetaminophen vs Codeine/Acetaminophen for Short-Term Pain Management Following ED Discharge.

    Science.gov (United States)

    Chang, Andrew K; Bijur, Polly E; Lupow, Jason B; Gallagher, E John

    2015-12-01

    To test the hypothesis that oxycodone/acetaminophen provides analgesia superior to codeine/acetaminophen following emergency department (ED) discharge. Prospective, randomized, double-blind, trial. Adult inner city ED. ED patients with acute extremity pain who were discharged home. Patients randomized to oxycodone/acetaminophen (5 mg/325 mg) or codeine/acetaminophen (30 mg/300 mg). The primary outcome, obtained via telephone one day after ED discharge, was the between-group difference in improvement in numerical rating scale (NRS) pain scores over a 2-hour period following the most recent ingestion of study drug. Secondary outcomes included proportion of patients with >50% pain reduction, side-effect profile, and patient satisfaction. Two hundred and forty patients were enrolled. Mean baseline NRS scores were 7.9 in both groups. Mean decrease over 2 hours was 4.5 NRS units in the oxycodone/acetaminophen group vs 4.2 NRS units in the codeine/acetaminophen group, for a clinically and statistically nonsignificant difference of 0.2 NRS units (95% CI -0.4-0.9 NRS units). Similarly, 66% vs 61% achieved >50% pain relief for a nonsignificant difference of 5% (95% CI -8% to 17%). Side-effect profile and patient satisfaction were similar. Our hypothesis that oxycodone/acetaminophen provides analgesia superior to codeine/acetaminophen was rejected. Although pain within each group was reduced by more than half, the between-group difference was not significant. Pending independent validation, these unexpected findings suggest that codeine/acetaminophen, a Schedule III agent, may be a clinically reasonable outpatient opioid alternative to oxycodone/acetaminophen, a more tightly restricted Schedule II agent thought to be more prone to misuse. Wiley Periodicals, Inc.

  2. Estudio de las curvas epicicloide y evolvente para formar el perfil de los engranajes que operan con distancia entre centros variable. // Study of the epicycloid and involute curves to form the profile of gears with variable center distance.

    Directory of Open Access Journals (Sweden)

    L. I. Negrín Hernández

    2007-09-01

    Full Text Available En este trabajo se realiza un estudio de las curvas epicicloidales y evolventes de círculo en sus formas generales, con elobjetivo de formar el perfil de trabajo de los dientes de los engranajes que operan con distancia entre centros variable. Separte de las expresiones generales de estas curvas y se desarrollan las fórmulas para determinar algunas propiedades de lasmismas, como el radio de curvatura, la involuta, etc. Aquí se realiza también la demostración de que la evolvente de círculoes un caso particular de la epicicloide, demostración que no aparece en la literatura especializada. Con posterioridad se haceuna comparación teniendo en cuenta las propiedades cinemáticas de los engranajes formados por las diferentes curvas.Como conclusiones del trabajo se plantea que la evolvente de círculo común tiene las mejores propiedades para engranajesque trabajan con una variación de la distancia entre centros menor que el 5 %, mientras que la epicicloide alargadagarantiza un mejor funcionamiento para engranajes que trabajen con una variación entre el 5 y el 10 %.Palabras claves: epicicloide, involuta, diente de engranaje, geometría de engranaje.____________________________________________________________________________Abstract:In this work is carried out a study of the epicycloid and circle involutes curves in their general forms, with the objective offorming the working profile of the gear teeth that operate with variable center distance. From the general expressions ofthese curves and the formulas are developed formulae to determine some of their properties, as the curvature radius, theinvolute, etc. It is also carried out the demonstration that the circle involute is a peculiar case of the epicycloid,demonstration that does not appear in the specialized literature. Moreover, a comparison is made keeping in mind thekinematics properties of gears formed by the different curves. As conclusions of the work is stated that the common

  3. Criminal Psychological Profiling

    Science.gov (United States)

    1993-10-18

    landmark report became known to the general population. Dr. Langer’s profile broke new ground. While the practice of psychoanalysis was not new, this marked...school or college dropout. Suspect is probably suffering from one or more forms of paranoid psychosis .6 Perpetrator: Based on this profile, the police

  4. Microbiologic methods utilized in the MAL-ED cohort study.

    Science.gov (United States)

    Houpt, Eric; Gratz, Jean; Kosek, Margaret; Zaidi, Anita K M; Qureshi, Shahida; Kang, Gagandeep; Babji, Sudhir; Mason, Carl; Bodhidatta, Ladaporn; Samie, Amidou; Bessong, Pascal; Barrett, Leah; Lima, Aldo; Havt, Alexandre; Haque, Rashidul; Mondal, Dinesh; Taniuchi, Mami; Stroup, Suzanne; McGrath, Monica; Lang, Dennis

    2014-11-01

    A central hypothesis of The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) study is that enteropathogens contribute to growth faltering. To examine this question, the MAL-ED network of investigators set out to achieve 3 goals: (1) develop harmonized protocols to test for a diverse range of enteropathogens, (2) provide quality-assured and comparable results from 8 global sites, and (3) achieve maximum laboratory throughput and minimum cost. This paper describes the rationale for the microbiologic assays chosen and methodologies used to accomplish the 3 goals. © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  5. Safe Handling of Snakes in an ED Setting.

    Science.gov (United States)

    Cockrell, Melanie; Swanson, Kristofer; Sanders, April; Prater, Samuel; von Wenckstern, Toni; Mick, JoAnn

    2017-01-01

    Efforts to improve consistency in management of snakes and venomous snake bites in the emergency department (ED) can improve patient and staff safety and outcomes, as well as improve surveillance data accuracy. The emergency department at a large academic medical center identified an opportunity to implement a standardized process for snake disposal and identification to reduce staff risk exposure to snake venom from snakes patients brought with them to the ED. A local snake consultation vendor and zoo Herpetologist assisted with development of a process for snake identification and disposal. All snakes have been identified and securely disposed of using the newly implemented process and no safety incidents have been reported. Other emergency department settings may consider developing a standardized process for snake disposal using listed specialized consultants combined with local resources and suppliers to promote employee and patient safety. Copyright © 2017 Emergency Nurses Association. Published by Elsevier Inc. All rights reserved.

  6. Modular forms

    NARCIS (Netherlands)

    Edixhoven, B.; van der Geer, G.; Moonen, B.; Edixhoven, B.; van der Geer, G.; Moonen, B.

    2008-01-01

    Modular forms are functions with an enormous amount of symmetry that play a central role in number theory, connecting it with analysis and geometry. They have played a prominent role in mathematics since the 19th century and their study continues to flourish today. Modular forms formed the

  7. Prepared for the unthinkable: EDs respond to terrorist attacks.

    Science.gov (United States)

    2001-11-01

    The response to the terrorist attacks at the World Trade Center and the Pentagon provided many key lessons for disaster preparedness. Volunteer physicians were not used in most cases, but EDs recognized the need for a system to check credentials. Communication from disater sites was problem. Injured patients went to the nearest hospital, even if it was not the most appropriate hospital. Experts recommend using existing disaster plans as templates to design or update your own.

  8. MobilED: a step backwards to look ahead

    CSIR Research Space (South Africa)

    Van Den Berg, M

    2008-10-01

    Full Text Available of technology development and the widespread integration of the device in social and cultural practices (Kress & Pachler, 2007), has created unique opportunities for educators, researchers and practitioners. Mobile learning has developed from a few small scale... only ever reach a small fraction of them, while the network of invisible computers continues its exponential penetration into those same regions, below the radar(Selanikio, 2008). MobilED (Mobile Education) (2005) started as an international...

  9. Interact-ed interwinning nature of virtual reality

    OpenAIRE

    Özenç, Kürşat Fatih; Ozenc, Kursat Fatih

    2004-01-01

    In our highly computerized world, we live in an environment which resembles an intertwining mobius of 'real' and 'virtual'. In interact-ed's visual context, the virtual and the real have been quettioned with respect to this interrelation. The investigation is moreover done with the concept of dreams. Dreams, like virtual environments, affect our life 'apperently'; not 'really'. As affective experiences, virtual (environments) and dreams are tightly related to each other. In somne conditions t...

  10. Active Intervention Can Decrease Burnout In Ed Nurses.

    Science.gov (United States)

    Wei, Rong; Ji, Hong; Li, Jianxin; Zhang, Liyao

    2017-03-01

    The aim of this study was to evaluate whether active intervention can decrease job burnout and improve performance among ED nurses. This study was carried out in the emergency departments of 3 hospitals randomly selected from 8 comprehensive high-level hospitals in Jinan, China. A total of 102 nurses were enrolled and randomly divided into control and intervention groups. For 6 months, nurses in intervention groups were treated with ordinary treatment plus comprehensive management, whereas nurses in the control group were treated with ordinary management, respectively. Questionnaires were sent and collected at baseline and at the end of the study. The Student t test was used to evaluate the effect of comprehensive management in decreasing burnout. All ED nurses showed symptoms of job burnout at different levels. Our data indicated that comprehensive management significantly decreased emotional exhaustion and depersonalization (P burnout in ED nurses and contribute to relieving work-related stress and may further protect against potential mental health problems. Copyright © 2016 Emergency Nurses Association. Published by Elsevier Inc. All rights reserved.

  11. Teachers are students in ZPG program called 'Pop Ed.'.

    Science.gov (United States)

    Schline, S

    1977-01-01

    Zero Population Growth's Population Education (Pop Ed) program began in 1975 as an ongoing effort to bring the "real world" into the classroom by demonstrating the relationships among population trends, food and energy resources, and environmental and economic problems. The training workshops which last for a day or 2 have the following goals: 1) to offer a brief demographic overview for teachers, 2) to provide lesson plans and techniques readily usable in the classroom, 3) to alert teachers to the best written and audiovisual materials available, 4) to identify local resources for teaching Pop Ed, and 5) to provide sample materials. In the 1st year of program operation 10 workshops were held. These workshops are credited, at least partly, with the subsequent population instruction that reached over 10,400 students and 1600 teachers. Another 15 workshops were held in the 2nd year of operation. Obstacles to the program are the assumption on the part of some teachers that Pop Ed belongs in disciplines other than their own and the belief on the part of many teachers that they will require extensive training.

  12. States leverage telepsychiatry solutions to ease ED crowding, accelerate care.

    Science.gov (United States)

    2015-02-01

    Many states are having success turning to telepsychiatry-based solutions to connect mental health patients with needed care while also decompressing crowded EDs. Just one year into a statewide telepsychiatry initiative in North Carolina (NC-STeP), administrators say the approach has saved as much as $7 million, and hospital demand for the service is higher than anticipated. In Texas, mental health emergency centers (MHEC) that use telepsychiatry to connect patients in rural areas with needed psychiatric care are freeing up EDs to focus on medical care. In just 11 months, 91 North Carolina hospitals have at least started the process to engage in NC-STeP. Much of the savings from NC-STeP come from involuntary commitment orders being overturned as a result of the telepsychiatry consults, reducing the need for expensive inpatient care. Implementing NC-STeP has involved multiple hurdles including credentialing difficulties and technical/firewall challenges. The Texas model provides 24/7 availability of psychiatrists via telemedicine through a network of MHECs. In-person staff at the MHECs perform basic screening tests and blood draws so that medical clearance can be achieved without the need for an ED visit in most cases. Funding for the MHECs comes from the state, hospitals in the region, and local governmental authorities that reap savings or benefits from the initiative.

  13. Profiling nursing resources in Australian emergency departments.

    Science.gov (United States)

    Morphet, Julia; Kent, Bridie; Plummer, Virginia; Considine, Julie

    2016-02-01

    Emergency nurses have a key role in managing the large numbers of patients that attend Australian emergency departments (EDs) annually, and require adequate educational preparation to deliver safe and quality patient care. This paper provides a detailed profile of nursing resources in Australian EDs, including ED locations, annual patient attendances, nurse staffing including level of education, and educational resources. Data were collected via online surveys of emergency Nurse Unit Managers and Nurse Educators and the MyHospitals website. Data were analysed by hospital peer group and state or territory. Comparisons were made using the Kruskal-Wallis Test and Spearman Rank Order Correlation. In 2011-2012, there were a median of 36,274 patient attendances to each of the 118 EDs sampled (IQR 28,279-46,288). Most of the nurses working in EDs were Registered Nurses (95.2%). Organisations provided educational resources including Clinical Nurse Educators (80.6%), learning packages (86%) and facilitation of postgraduate study (98%), but resources, both human and educational varied substantially between states and territories. One-third of emergency nurses held a relevant postgraduate qualification (30%). There are important variations in the emergency nursing resources available between Australian states and territories. The high percentage of RNs in Australian EDs is a positive finding, however strategies to increase the percentage of nurses with relevant postgraduate qualifications are required. Copyright © 2016 College of Emergency Nursing Australasia Ltd. Published by Elsevier Ltd. All rights reserved.

  14. Analysis of microtraces in invasive traumas using SEM/EDS.

    Science.gov (United States)

    Vermeij, E J; Zoon, P D; Chang, S B C G; Keereweer, I; Pieterman, R; Gerretsen, R R R

    2012-01-10

    Scanning electron microscopy in combination with energy-dispersive X-ray spectrometry (SEM/EDS) is a proven forensic tool and has been used to analyze several kinds of trace evidence. A forensic application of SEM/EDS is the examination of morphological characteristics of tool marks that tools and instruments leave on bone. The microtraces that are left behind by these tools and instruments on the bone are, however, often ignored or not noticed at all. In this paper we will describe the use of SEM/EDS for the analysis of microtraces in invasive sharp-force, blunt-force and bone-hacking traumas in bone. This research is part of a larger multi-disciplinary approach in which pathologists, forensic anthropologists, toolmark and microtrace experts work together to link observed injuries to a suspected weapon or, in case of an unknown weapon, to indicate a group of objects that could have been used as a weapon. Although there are a few difficulties one have to consider, the method itself is rather simple and straightforward to apply. A sample of dry and clean bone is placed into the SEM sample chamber and brightness and contrast are set such that bone appears grey, metal appears white and organic material appears black. The sample is then searched manually to find relevant features. Once features are found their elemental composition is measured by an energy dispersive X-ray spectrometer (EDS). This method is illustrated using several cases. It is shown that SEM/EDS analysis of microtraces in bone is a valuable tool to get clues about an unknown weapon and can associate a specific weapon with injuries on the basis of appearance and elemental composition. In particular the separate results from the various disciplines are complementary and may be combined to reach a conclusion with a stronger probative value. This is not only useful in the courtroom but above all in criminal investigations when one have to know for what weapon or object to look for. Copyright © 2011

  15. Health care utilization before and after an outpatient ED visit in older people.

    Science.gov (United States)

    Horney, Carolyn; Schmader, Kenneth; Sanders, Linda L; Heflin, Mitchell; Ragsdale, Luna; McConnell, Eleanor; Hocker, Michael; Hastings, S Nicole

    2012-01-01

    Older adults in the United States receive a significant amount of care in the emergency department (ED), yet the associations between ED and other types of health care utilization have not been adequately studied in this population. The goals of this study were to examine the relationships between health care use before and after an ED visit among older adults. This retrospective cohort study examined health care use among 308 patients 65 years or older discharged from a university-affiliated ED. Proportional-hazards models were used to assess the relationship between pre-ED health care use (primary care physician [PCP], specialist, ED, and hospital) and risk of return ED visits. Older ED patients in this study had visited other types of providers frequently in the previous year (median number of PCP and specialist visits, 4). Patients who used the ED on 2 or more occasions in the previous year were found to have visited their PCP more often than those without frequent ED use (median number of visits, 7.0 vs 4.0; P < .001). Despite more PCP use in this population, frequent ED use was associated with increased risk of a repeat ED visit (hazard ratio, 2.20; 95% confidence interval, 1.15-4.21), in models adjusted for demographics and health status. Older adults who use the ED are also receiving significant amounts of care from other sources; simply providing additional access to care may not improve outcomes for these vulnerable individuals. Published by Elsevier Inc.

  16. EDS coal liquefaction process development. Phase V. EDS commercial plant study design update. Illinois coal. Volume 1. Main report

    Energy Technology Data Exchange (ETDEWEB)

    Epperly, W. R.

    1981-03-01

    The objectives of the Study Design Update (SDU) were to identify the technical issues facing a potential commercial-size EDS plant design; to provide a reliable basis for estimating the cost of EDS products; and to furnish research guidance to the EDS Project. The SDU consists of two distinct studies in which different processing schemes are used to produce the hydrogen and fuel gas required by the plant. These studies are referred to as the Base Case and the Market Flexibility Sensitivity Case. In the Base Case, hydrogen is generated by steam reforming of the light hydrocarbon gases produced in the plant. Fuel gas is generated by feeding the bottoms stream from the liquefaction section vacuum pipestill to a FLEXICOKING unit. In the FLEXICOKING unit reactor, the bottoms stream is converted to coke; additional liquid product is also recovered. The coke is converted to low-Btu fuel gas in the FLEXICOKING unit gasifier. In the Market Flexibility Sensitivity (MFS) Case, the bottoms stream from the vacuum pipestill is split, and about half is sent to the FLEXICOKING unit for recovery of additional liquid product and production of fuel gas. The remainder of the bottoms stream is converted to hydrogen in a Partial Oxidation Unit. Hence the MFS Case does not consume light hydrocarbon gases produced and they are available for sale. The study of these two cases has demonstrated the importance of bottoms process selection to the economics and thermal efficiency of an EDS plant. Volume 1 - Main Report has been developed to be a stand-alone document. Both the Base Case and Market Flexibility Sensitivity (MFS) Case are covered. This volume includes an overview and detailed case summaries. It also covers economics, product recovery factors, material and energy balances, cost estimates and enviromental considerations.

  17. Metabolic vs structural coma in the ED--an observational study.

    Science.gov (United States)

    Forsberg, Sune; Höjer, Jonas; Ludwigs, Ulf; Nyström, Harriet

    2012-11-01

    Patients presenting unconscious may reasonably be categorized as suffering from a metabolic or structural condition. The objective was to investigate if some routinely recorded clinical features may help to distinguish between these 2 main forms of coma in the emergency department (ED). Adults admitted to an ED in Stockholm between February 2003 and May 2005 with a Glasgow Coma Scale (GCS) score less than 11 were enrolled prospectively. The GCS score was entered into a protocol that was complemented with available data within 1 month. The study population of 875 patients was classified into 2 main groups: one with a metabolic (n = 633; 72%) and one with a structural disorder (n = 242; 28%). Among the clinical features recorded in the ED, 3 were found to be strongly associated with a metabolic disorder, namely, young age, low or normal blood pressure, and absence of focal signs in the neurological examination. Patients younger than 51 years with a systolic blood pressure less than 151 mm Hg who did not display signs of focal pathology had a probability of 96% for having a metabolic coma. The mean GCS score on admission was identical in the groups. Hospital mortality was 14% in the metabolic and 56% in the structural group. These findings indicate that unconscious young adults who present without a traumatic incident with a low or normal blood pressure and without signs of focal pathology most probably suffer from a metabolic disorder, wherefore computed tomography of the brain may be postponed and often avoided. Copyright © 2012 Elsevier Inc. All rights reserved.

  18. La narrazione orale tra bambini ed adulti: da flusso continuo a vena carsica?

    Directory of Open Access Journals (Sweden)

    Milena Bernardi

    2010-02-01

    Full Text Available Con il segmento di ricerca che viene presentato nella sua prima fase si prende in esame l’ipotesi di un processo, in atto da tempo, di trasformazione e/o di declino della narrazione orale nel rapporto quotidiano tra adulti e bambini, inteso, in questo specifico contesto, come “spia” dei mutamenti degli stili educativi e degli interscambi tra famiglie ed operatori dei servizi in relazione all’alleanza educativa. La complessità dei filoni di studio che rimandano alla voce “narrazione” negli ambiti delle scienze umane esige la precisazione della curvatura “narrativa” scelta per la ricerca in corso: curvatura che appartiene all’epistemologia della letteratura per l’infanzia e della pedagogia della narrazione in quanto permette di imboccare la strada della ricerca pedagogica rivolta innanzi tutto ai significati che il narrare assume nella relazione educativa e poi ai modi ed alle forme della narrazione che coinvolgono l’infanzia. In un’epoca di grande vitalità e visibilità delle narrazioni, tra cui abbondano le produzioni scritte, illustrate, filmate per l’infanzia, sembra esserci una zona marginale e quasi sommersa della comunicazione narrante che rischia di sfumare in una sorta di oblio. E’ la zona della narrazione orale esperita in praesentia da bambini ed adulti insieme, tessuta con fili di parole che restituiscono senso all’intero arco delle esperienze, tentando di riordinare il disordine che spesso connota la realtà, interpretando, stabilendo connessioni, impregnando di quel senso i vissuti, i fatti, le relazioni, le cose e le parole stesse, ancora, nelle voci. Del rischio e delle conseguenze che possono derivare dalla sua mancanza si occupa questo contributo di ricerca che, dal punto di vista metodologico, si è avvalso e si avvale sia di analisi condotte sul corpus dei testi sia della raccolta di dati e informazioni tramite incontri condotti con la modalità del focus group, con educatrici e genitori.

  19. Composition and microstructure of MTA and Aureoseal Plus: XRF, EDS, XRD and FESEM evaluation.

    Science.gov (United States)

    Cianconi, L; Palopoli, P; Campanella, V; Mancini, M

    2016-12-01

    The aim of this study was to determine the chemical composition and the phases' microstructure of Aureoseal Plus (OGNA, Italy) and ProRoot MTA (Dentsply Tulsa Dental, USA) and to compare their characteristics. Study Design: Comparing Aureoseal Plus and ProRoot MTA microstructure by means of several analyses type. The chemical analysis of the two cements was assessed following the UNI EN ISO 196-2 norm. X-Ray fluorescence (XRF) was used to determine the element composition. The crystalline structure was analysed quantitatively using x-ray diffraction (XRD). Powders morphology was evaluated using a scanning electron microscope (SEM) with backscattering detectors, and a field emission scanning electron microscope (FESEM). Elemental analysis was performed by energy dispersive x-ray analysis (EDS). The semi-quantitative XRF analysis showed the presence of heavy metal oxides in both cements. The XRD spectra of the two cements reported the presence of dicalcium silicate, tricalcium silicate, tricalcium aluminate, tetracalcium aluminoferrite, bismuth oxide and gypsum. SEM analysis showed that ProRoot MTA powder is less coarse and more homogeneous than Aureoseal. Both powders are formed by particles of different shapes: round, prismatic and oblong. The EDS analysis showed that some ProRoot MTA particles, differently from Aureoseal, contain Ca, Si, Al and Fe. Oblong particles in ProRoot and Aureoseal are rich of bismuth. The strong interest in developing new Portland cement-based endodontic sealers will create materials with increased handling characteristics and physicochemical properties. A thorough investigation on two cement powders was carried out by using XRF, XRD, SEM and EDS analysis. To date there was a lack of studies on Aureoseal Plus. This cement is similar in composition to ProRoot MTA. Despite that it has distinctive elements that could improve its characteristics, resulting in a good alternative to MTA.

  20. The vitamin D analogue ED71 but Not 1,25(OH2D3 targets HIF1α protein in osteoclasts.

    Directory of Open Access Journals (Sweden)

    Yuiko Sato

    Full Text Available Although both an active form of the vitamin D metabolite, 1,25(OH2D3, and the vitamin D analogue, ED71 have been used to treat osteoporosis, anti-bone resorbing activity is reportedly seen only in ED71- but not in 1,25(OH2D3 -treated patients. In addition, how ED71 inhibits osteoclast activity in patients has not been fully characterized. Recently, HIF1α expression in osteoclasts was demonstrated to be required for development of post-menopausal osteoporosis. Here we show that ED71 but not 1,25(OH2D3, suppress HIF1α protein expression in osteoclasts in vitro. We found that 1,25(OH2D3 or ED71 function in osteoclasts requires the vitamin D receptor (VDR. ED71 was significantly less effective in inhibiting M-CSF and RANKL-stimulated osteoclastogenesis than was 1,25(OH2D3 in vitro. Downregulation of c-Fos protein and induction of Ifnβ mRNA in osteoclasts, both of which reportedly block osteoclastogenesis induced by 1,25(OH2D3 in vitro, were both significantly higher following treatment with 1,25(OH2D3 than with ED71. Thus, suppression of HIF1α protein activity in osteoclasts in vitro, which is more efficiently achieved by ED71 rather than by 1,25(OH2D3, could be a reliable read-out in either developing or screening reagents targeting osteoporosis.

  1. The SIAMS-ED Trial: A National, Independent, Multicentre Study on Cardiometabolic and Hormonal Impairment of Men with Erectile Dysfunction Treated with Vardenafil

    Directory of Open Access Journals (Sweden)

    Andrea M. Isidori

    2014-01-01

    Full Text Available Increased cardiovascular risk has been associated with reduced response to proerectile drugs. The Italian Society of Andrology and Sexual Medicine (SIAMS promoted an independent, multicenter study performed in 604 men (55 ± 12 yrs suffering from erectile dysfunction (ED to assess multiple health outcomes and response to 6-month vardenafil challenge in a real-life setting. Overall, 30.8% men had metabolic syndrome. Cardiovascular risk stratification revealed a greater number of ED subjects with moderate risk of a major adverse cardiovascular event than the general population (P<0.01. Age-adjusted pulse pressure was positively correlated with ED severity and negatively with androgens and waist circumference (P<0.01. A decline in total testosterone was observed with increasing arterial pulse pressure (P<0.05, which was not accompanied by compensatory LH rise. Follow-up on 185 men treated with vardenafil in an nonrandomized, open, single-arm trial documented a significant rise in IIEF-5 (delta = 6.1 ± 4.8 that was maintained in men with high cardiovascular risk. Mild adverse events occurred in <5%, with no differences between cardiovascular risk classes. In summary, ED is a frequent symptom in patients with an elevated, but often unknown, risk of future cardiovascular events. Androgens predict vascular resistance in ED patients. Vardenafil’s response and safety profile were preserved in subjects with higher cardiovascular risk.

  2. Prevalence and correlates of erectile dysfunction (ED) and treatment seeking for ED in Asian Men: the Asian Men's Attitudes to Life Events and Sexuality (MALES) study.

    Science.gov (United States)

    Tan, Hui-Meng; Low, Wah Yun; Ng, Chirk Jenn; Chen, Kuang-Kuo; Sugita, Minoru; Ishii, Nobuhisa; Marumo, Ken; Lee, Sung Won; Fisher, William; Sand, Michael

    2007-11-01

    There have been limited multiregional studies in Asia examining the parameters of men's general and sexual health and quality of life in the general population vs. those in clinical cohorts of patients with erectile dysfunction (ED). The aims of the Asian Men's Attitudes to Life Events and Sexuality (Asian MALES) study were to investigate the prevalence of ED, associated health conditions, and ED treatment-seeking patterns in the general male population in five regions of Asia (China, Japan, Korea, Malaysia, and Taiwan). Standardized questionnaire previously used in a similar multiregional study and modified to ensure culturally appropriate content for Asia. Phase I of the study involved 10,934 adult men, aged 20-75 years, who were interviewed using the standardized questionnaire. Phase II of the study involved men with self-reported ED recruited from Phase I and via physician referral, invitations in general practitioner offices, and street interception (total Phase II sample, N = 1,209). The overall prevalence of self-reported ED in the Phase I study population was 6.4%. ED prevalence varied by region and significantly increased with age (P quality of life (P = 0.0001), compared with men without ED. Phase II of the study revealed that fewer than half of men with self-reported ED had sought treatment for their problem. Men were more likely to seek help for erection difficulties from Western doctors than from traditional medicine practitioners (P = 0.0001). A man's partner/spouse was the most common influencer of treatment seeking in all regions except Malaysia. The findings confirm those of existing research on ED in both Asian and non-Asian males: ED is a prevalent condition; the prevalence of ED increases with age and is strongly associated with comorbid conditions; and the majority of men have never sought treatment for their condition. This study highlights a substantial need for the evaluation and treatment of ED in Asian men.

  3. Treatment of Nausea and Vomiting in Pregnancy: Factors Associated with ED Revisits

    Directory of Open Access Journals (Sweden)

    Brian R. Sharp

    2016-09-01

    Full Text Available Introduction: Nausea and vomiting in pregnancy (NVP is a condition that commonly affects women in the first trimester of pregnancy. Despite frequently leading to emergency department (ED visits, little evidence exists to characterize the nature of ED visits or to guide its treatment in the ED. Our objectives were to evaluate the treatment of NVP in the ED and to identify factors that predict return visits to the ED for NVP. Methods: We conducted a retrospective database analysis using the electronic medical record from a single, large academic hospital. Demographic and treatment variables were collected using a chart review of 113 ED patient visits with a billing diagnosis of “nausea and vomiting in pregnancy” or “hyperemesis gravidarum.” Logistic regression analysis was used with a primary outcome of return visit to the ED for the same diagnoses. Results: There was wide treatment variability of nausea and vomiting in pregnancy patients in the ED. Of the 113 patient visits, 38 (33.6% had a return ED visit for NVP. High gravidity (OR 1.31, 95% CI [1.06-1.61], high parity (OR 1.50 95% CI [1.12-2.00], and early gestational age (OR 0.74 95% CI [0.60-0.90] were associated with an increase in return ED visits in univariate logistic regression models, while only early gestational age (OR 0.74 95% CI [0.59-0.91] was associated with increased return ED visits in a multiple regression model. Admission to the hospital was found to decrease the likelihood of return ED visits (p=0.002. Conclusion: NVP can be difficult to manage and has a high ED return visit rate. Optimizing care with aggressive, standardized treatment in the ED and upon discharge, particularly if factors predictive of return ED visits are present, may improve quality of care and reduce ED utilization for this condition.

  4. Patient-Centered Care Transition for Patients Admitted through the ED: Improving Patient and Employee Experience

    OpenAIRE

    Andrea Algauer BSN, RN; Stephanie Rivera BSN, RN; Robert Faurote BSN, RN

    2015-01-01

    With increasing wait times in emergency departments (ED) across America, there is a need to streamline the inpatient admission process in order to decrease wait times and more important, to increase patient and employee satisfaction. One inpatient unit at New York-Presbyterian Weill Cornell Medical Center initiated a program to help expedite the inpatient admission process from the ED. The goal of the ED Bridge program is to ease the patient's transition from the ED to an inpatient unit by vi...

  5. Self-Esteem and Emotional Intelligence among B.Ed Trainees of Tsunami Affected Coastal Belt

    Science.gov (United States)

    Babu M, Sameer

    2008-01-01

    Through this study the author investigates the relationship between self-esteem and emotional intelligence among B.Ed trainees of Tsunami affected coastal belt of Alappey district of Kerala, India. Stream of study, marital status and age based comparisons were made among the B.Ed trainees. 92 B.Ed trainees were the participants in the study. It…

  6. Translation and psychometric properties of the Chinese (Mandarin) version of the Child Oral Health Impact Profile-Short Form 19 (COHIP-SF 19) for school-age children.

    Science.gov (United States)

    Li, Chenghao; Xia, Bin; Wang, Yu; Guan, Xuelin; Yuan, Junwei; Ge, Lihong

    2014-11-30

    Although caries and malocclusion occur with a high prevalence in Chinese school-age children, there were no appropriate instrument to assess the oral health-related quality of life (OHRQoL) for this population. The aim of our study was to develop a Chinese (Mandarin) version of the Child Oral Health Impact Profile-Short Form 19 (COHIP-SF 19) and provide a preliminary test of its psychometric properties. The Chinese version of COHIP-SF 19 was developed through a standard translation and back translation procedure. The psychometric properties of the instrument were tested among 644 school-age children in Beijing, China, including the internal consistency, test-retest reliability, discriminant and convergent validity. A Mann-Whitney U test was used to determine the capability of the instrument to differentiate children with different caries and malocclusion outcomes. And partial Spearman correlations were used to determine the relationships between the OHRQoL scores and clinical-severity indicators and self-perceived health ratings, respectively. Chinese school-age children had relatively high OHRQoL scores, in spite of the fact that oral impacts were quite common (56.3%). The internal consistency and retest reliability were good to excellent with a Chronbach's alpha of 0.81 and an intra-class correlation coefficient (ICC) of 0.77. Children who had active tooth decay or severe malocclusion had significantly lower COHIP-SF 19 scores (P ≤0.001). Girls had somewhat higher scores in the oral health and functional well-being subscales (P gender, and school district (│r s │ =0.11 - 0.51, P <0.05). We confirmed satisfactory psychometric properties for the Chinese version of COHIP-SF 19 in a community sample of Chinese school-age children. The OHRQoL instrument should play a more important role in future clinical studies, epidemiological surveys and potential public health policy in China.

  7. Book review: Psychology in a work context (2nd Ed.

    Directory of Open Access Journals (Sweden)

    Nanette Tredoux

    2003-10-01

    Full Text Available Bergh, Z. & Theron, A.L. (Eds (2003 Psychology in a work context (2nd Ed.. Cape Town: Oxford University Press. This book is an overview and introduction to Industrial and Organisational Psychology. It is a work of ambitious scope, and it is clear that the contributors have invested a great deal of thought and effort in the planning and execution of the book. The current version is the second edition, and it looks set to become one of those standard textbooks that are revised every few years to keep up with changing times. It is a handsome volume, produced to a high standard of editorial care, pleasingly laid out and organised well enough to be useful as an occasional reference source. An English-Afrikaans glossary, tables of contents for every chapter as well as for the entire book, a comprehensive index and extensive bibliography make it easy to retrieve the information relating to a particular topic. Every chapter ends with a conclusion summarising the gist of the material covered. Quality illustrations lighten the tone and help to bring some of the concepts to life. Learning outcomes and self-assessment exercises and questions for every chapter will be useful to the lecturer using the book as a source for a tutored course, and for the student studying by distance learning. If sold at the suggested retail price, the book represents good value compared to imported textbooks that cover similar ground.

  8. EMERGENCY DEPARTMENT (ED OVERCROWDING: EVIDENCE-BASED ANSWERS TO FREQUENTLY ASKED QUESTIONS

    Directory of Open Access Journals (Sweden)

    RJ Salway

    2017-03-01

    Full Text Available Overcrowding in emergency departments is a problem in many countries around the world, including the United States and Chile. Emergency department (ED overcrowding causes problems for patients and staff, including increased waiting times, increased ambulance diversion, increased length of stay, increased medical errors, increased patient mortality, and increased harm to hospitals due to financial losses. This article aims to describe the etiology of ED overcrowding and potential solutions through an examination of the evidence. Ultimately, ED overcrowding originates from hospital overcrowding and thus the solutions to this complex problem lie in the ED itself as well as outside of the ED.

  9. Improving ED specimen TAT using Lean Six Sigma.

    Science.gov (United States)

    Sanders, Janet H; Karr, Tedd

    2015-01-01

    Lean and Six Sigma are continuous improvement methodologies that have garnered international fame for improving manufacturing and service processes. Increasingly these methodologies are demonstrating their power to also improve healthcare processes. The purpose of this paper is to discuss a case study for the application of Lean and Six Sigma tools in the reduction of turnaround time (TAT) for Emergency Department (ED) specimens. This application of the scientific methodologies uncovered opportunities to improve the entire ED to lab system for the specimens. This case study provides details on the completion of a Lean Six Sigma project in a 1,000 bed tertiary care teaching hospital. Six Sigma's Define, Measure, Analyze, Improve, and Control methodology is very similar to good medical practice: first, relevant information is obtained and assembled; second, a careful and thorough diagnosis is completed; third, a treatment is proposed and implemented; and fourth, checks are made to determine if the treatment was effective. Lean's primary goal is to do more with less work and waste. The Lean methodology was used to identify and eliminate waste through rapid implementation of change. The initial focus of this project was the reduction of turn-around-times for ED specimens. However, the results led to better processes for both the internal and external customers of this and other processes. The project results included: a 50 percent decrease in vials used for testing, a 50 percent decrease in unused or extra specimens, a 90 percent decrease in ED specimens without orders, a 30 percent decrease in complete blood count analysis (CBCA) Median TAT, a 50 percent decrease in CBCA TAT Variation, a 10 percent decrease in Troponin TAT Variation, a 18.2 percent decrease in URPN TAT Variation, and a 2-5 minute decrease in ED registered nurses rainbow draw time. This case study demonstrated how the quantitative power of Six Sigma and the speed of Lean worked in harmony to improve

  10. Temperature dependence of direct current conductivity in Ag-ED20 nanocomposite films

    Science.gov (United States)

    Novikov, G. F.; Rabenok, E. V.; Bogdanova, L. M.; Irzhak, V. I.

    2017-10-01

    The effect of silver nanoparticles (NPs) in the concentration range of ≤0.8 wt % have on direct current conductivity σdc of Ag-ED20 nanocomposite is studied by method of broadband dielectric spectroscopy (10-2-105 Hz) method of broadband dielectric spectroscopy. It is found that temperature dependence σdc consists of two sections: above the glass transition temperature ( T g), the dependence corresponds to the empirical Vogel-Fulcher-Tammann law (Vogel temperature T 0 does not depend on the NP concentration); below T g, the dependence is Arrhenius with activation energy E a ≈ 1.2 eV. In the region where T > T g, the σdc value grows along with NP concentration. It is concluded that the observed broken form of the temperature dependence is apparently due to a change in the conduction mechanism after the freezing of ion mobility at temperatures below T g.

  11. A study of two generic health-related quality of life questionnaires--Nottingham Health Profile and Short-Form 36 Health Survey--and of coping in patients with sensory hyperreactivity.

    Science.gov (United States)

    Kristofferzon, Marja-Leena; Ternesten-Hasséus, Ewa

    2013-10-29

    Sensory hyperreactivity (SHR) is one explanation for airway symptoms induced by chemicals and scents. Little is known about health-related quality of life (HRQOL) and coping, in this group of patients. A study was done in patients with SHR to (1) compare the Nottingham Health Profile (NHP) and the Short-Form 36 Health Survey (SF-36) in regard to their suitability, validity, reliability, and acceptability; (2) evaluate how the patients cope with the illness; (3) assess whether there are differences between women and men with respect to HRQOL and coping; and (4) assess whether there are differences between patients and normative data with respect to HRQOL and coping. A total of 115 patients (91 women) with SHR were asked to answer five questionnaires: a study-specific questionnaire, the Chemical Sensitivity Scale for Sensory Hyperreactivity (CSS-SHR), the NHP, the SF-36, and the Jalowiec Coping Scale-60. Eighty-three patients (72%; 70 women) completed all questionnaires. The SF-36 scores were less skewed and more homogeneously distributed and showed fewer floor and ceiling effects than the NHP scores. The SF-36 was also discriminated better between patients with high and low CSS-SHR scores. The reliability standard for both questionnaires was satisfactory. There were no gender differences in HRQOL. Patients with SHR had significantly lower HRQOL scores than the normative data in comparable domains of the NHP and the SF-36: emotional reactions/mental health, energy/vitality, physical mobility/functioning, and pain/bodily pain. In social isolation/functioning, the results were different; the NHP scores were similar to the normative data and the SF-36 scores were lower. The most commonly used coping styles were optimistic, self-reliant, and confrontational. Women used optimistic coping more than men. Compared with the normative group, patients with SHR used confrontational and optimistic coping more and emotive coping less. The current findings showed that both the NHP

  12. Fisica e fumetti: Paperone ed il deposito sotterraneo

    CERN Document Server

    Bagnoli, Franco

    2011-01-01

    I fumetti, come i film, spesso utilizzano idee scientifiche "fantasiose". Non ci riferiamo qui alla violazione implicita delle leggi della fisica, cosa permessa in un mondo di fantasia, quanto piuttosto all'uso di spiegazioni fisiche errate che vengono usate in buona fede perch\\'e a riflettono convinzioni molto diffuse, ma sbagliate, sull'interpretazione di fenomeni a partire dai principi fisici. D'altra parte questi errori possono servire a illustrare la corretta applicazione della fisica in una maniera molto pi\\`u accattivante rispetto alla modalit\\'a tradizionale di presentazione. Analizziamo qui l'avventura Paperone ed il deposito sotterraneo di Pezzin e Cavezzano. ----- Comics and cartoon movies sometimes exploit fictitious scientific ideas. It is often the case that these ideas, althought wrong, actually reflect the popular vision of some natural phenomenon. We do not refer here to the implicit violation of physical laws in fictions, a practice allowed by the underlining "poetic licence" of comics. Howe...

  13. Proteste ed emancipazione alla frontiera europea. Il caso di Lampedusa

    Directory of Open Access Journals (Sweden)

    Annalisa Lendaro

    Full Text Available Riassunto Questo articolo si propone di approfondire a livello teorico i legami tra proteste ed emancipazione dei migranti senza status legale, che si trovano in situazione di detenzione amministrativa sull’isola italiana di Lampedusa. Il presente contributo mette in evidenza il fatto che l’agency dei migranti, seppur privi di libertà e di uno status legale, è determinante per sbloccare una situazione di crisi in un contesto simile allo stato di eccezione descritto da Agamben. Più precisamente, la protesta dei migranti di Lampedusa mostra in che modo la sospensione dello stato di diritto apra degli spiragli per, non solo denunciare l’ingiustizia di alcune norme, ma anche per agire.

  14. EDS'09: 13th International Conference on Elastic & Diffractive Scattering

    CERN Multimedia

    CERN. Geneva

    2009-01-01

    The series of International Conferences on Elastic and Diffractive Scattering was founded in 1985 in the picturesque old French town of Blois, famous for its XIV - XVIIth century château, inside of which the first meeting took place. Since then, meetings have been organised every two years in different places of the world: New York (1987), Evanston (1989), Isola d'Elba (1991), Providence (1993), Blois (1995), Seoul (1997), Protvino (1999), Prague (2001), Helsinki (2003), Blois (2005) and Hamburg (2007). The conference will focus on the most recent experimental and theoretical results in particle physics with an emphasis on Quantum Chromodynamics (QCD). http://cern.ch/eds09/ The conference agenda is now full. No further contributions can be accepted.

  15. Data Profiling

    OpenAIRE

    Hladíková, Radka

    2010-01-01

    Title: Data Profiling Author: Radka Hladíková Department: Department of Software Engineering Supervisor: Ing. Vladimír Kyjonka Supervisor's e-mail address: Abstract: This thesis puts mind on problems with data quality and data profiling. This Work analyses and summarizes problems of data quality, data defects, process of data quality, data quality assessment and data profiling. The main topic is data profiling as a process of researching data available in existing...

  16. Comparative study on the regeneration of flue-gas desulfurizing agents by using conventional electrodialysis (ED) and bipolar membrane electrodialysis (BMED)

    Energy Technology Data Exchange (ETDEWEB)

    Chuanhui Huang; Tongwen Xu [University of Science and Technology of China, Hefei (China). Laboratory of Functional Membranes, School of Chemistry and Material Science

    2006-09-01

    Piperazine (Pz) is an ideal desulfurizing agent but the heat-stable salts formed in desulfurization have caused secondary pollution and waste of resources. In the previous paper, a method was reported to regenerate piperazine by using bipolar membrane electrodialysis (BMED). To find the variety of that regeneration process, experiments were performed on the regeneration of piperazine by using ED. In comparison, ED has higher piperazine yield and current efficiency, and much lower voltage drop and energy consumption. However, its process cost is higher than that of BMED due to an extra expenditure for the base and its tank and pumps. The process cost is estimated to be 0.96 $/kg Pz for BMED and 1.14 $/kg Pz for ED. Notably, BMED has more environmental benefits and will be more economically attractive as the control on secondary pollution is strengthened and the bipolar membrane cost decreases. 9 refs., 4 figs., 1 tab.

  17. Pivot Nursing: An Alternative to Traditional ED Triage.

    Science.gov (United States)

    Christensen, Maria; Rosenberg, Mark; Mahon, Eileen; Pineda, Sharon; Rojas, Eva; Soque, Victoria; Johansen, Mary L

    2016-09-01

    A 7.2% increase in patient volume from 130,700 to 140,800 in 2012 prompted St Joseph's Regional Medical Center Emergency Department to review existing triage processes to decrease turnaround time. "Pivot triage" is a new, efficient intake process that entails use of 4 rather than 8 determinants to identify acuity levels. The purpose of this performance improvement project was to create alternatives to traditional triage to decrease ED length of stay and door-to-physician time. After education, the pivot process was implemented using 4 determinants established by a multidisciplinary team. The pivot process was slowly implemented for 6 hours over a 1-week period to work out processing issues. Arrival time, door-to-physician time, and departure time from the emergency department were elements used to calculate the patient's turnaround time. Length of ED stay was collected monthly beginning in the fourth quarter of 2011. Comparisons were made after Pivot implementation in the fourth quarter of 2012. Despite the increasing volume, the mean door-to-physician time decreased from 71 to 40 minutes, a 43.7% reduction. The overall turnaround time decreased from 220 to 181 minutes, representing approximately a 17.7% reduction. The percentage of patients who left without being seen decreased from 2.5% to 1.0%. The pivot process improved patient flow in the emergency department, reducing time spent by the patient in the department. The pivot process is a viable alternative to traditional triage. Nurses are able to accurately pivot patients with a reduced amount of information. Copyright © 2016 Emergency Nurses Association. Published by Elsevier Inc. All rights reserved.

  18. ED services: the impact of caring behaviors on patient loyalty.

    Science.gov (United States)

    Liu, Sandra S; Franz, David; Allen, Monette; Chang, En-Chung; Janowiak, Dana; Mayne, Patricia; White, Ruth

    2010-09-01

    This article describes an observational study of caring behaviors in the emergency departments of 4 Ascension Health hospitals and the impact of these behaviors on patient loyalty to the associated hospital. These hospitals were diverse in size and geography, representing 3 large urban community hospitals in metropolitan areas and 1 in a midsized city. Research assistants from Purdue University (West Lafayette, IN) conducted observations at the first study site and validated survey instruments. The Purdue research assistants trained contracted observers at the subsequent study sites. The research assistants conducted observational studies of caregivers in the emergency departments at 4 study sites using convenience sampling of patients. Caring behaviors were rated from 0 (did not occur) to 5 (high intensity). The observation included additional information, for example, caregiver roles, timing, and type of visit. Observed and unobserved patients completed exit surveys that recorded patient responses to the likelihood-to-recommend (loyalty) questions, patient perceptions of care, and demographic information. Common themes across all study sites emerged, including (1) the area that patients considered most important to an ED experience (prompt attention to their needs upon arrival to the emergency department); (2) the area that patients rated as least positive in their actual ED experience (prompt attention to their needs upon arrival to the emergency department); (3) caring behaviors that significantly affected patient loyalty (eg, making sure that the patient is aware of care-related details, working with a caring touch, and making the treatment procedure clearly understood by the patient); and (4) the impact of wait time to see a caregiver on patient loyalty. A number of correlations between caring behaviors and patient loyalty were statistically significant (P caring behaviors that are most closely linked to patient loyalty but that occurred least frequently. The

  19. Lack of information underlies women's perceptions of erectile dysfunction (ED) drugs in Japan.

    Science.gov (United States)

    Mita, Koji; Kakehashi, Masayuki; Hasegawa, Yasuhisa; Inoue, Yoji; Shigeta, Masanobu; Matsubara, Akio; Usui, Tsuguru

    2008-12-01

    Some Japanese women are known to have negative attitudes toward erectile dysfunction (ED) drugs, but the environment underlying these perceptions is unclear. To reveal the underlying environment that shapes women's perceptions of ED drugs in Japan. A web-based questionnaire was conducted through an Internet-based market research company. A total of 2,593 women in five age groups (20s, 30s, 40s, 50s, and 60s or older) were randomly invited to participate in this study, with an almost equal number in each age group. The questionnaire contained 30 items related to individual background and sexual information, concerns about the image of ED drugs, ED drug-related perceptions, and attitude toward sexual information media. The women's attitude and the independent predictors that affect their partner's use of ED drugs were clarified. Answers were obtained from 1,077 women, of whom 35.4% (n=381) had a negative image of ED drugs. Although 69.5% (n=749) agreed that a sexual relationship with a male partner was important, only 26.7% (n=288) agreed that this remained important if ED drugs were used. However, 56.7% (n=611) and 57.7% (n=621) of respondents, respectively, answered that they would allow their partner's use of ED drugs if they imagined that they understood the safety and effectiveness of ED drugs and that their quality of life was improved by their partner's use of the drugs. Lack of information about ED drugs was a significant predictor for acceptance of a partner's use of ED drugs among women with a negative image of ED drugs, since they were more likely to accept the use of these drugs if they were convinced about their safety and effectiveness or positive effect on quality of life. Lack of information about ED drugs may influence the perception of women in Japan regarding these drugs.

  20. RT-PCR Analysis of ED-A,ED-B, and IIICS Fibronectin Domains: A New Screening Marker For Bladder Cancer

    Directory of Open Access Journals (Sweden)

    M Ahmadi Javid

    2004-12-01

    Full Text Available Background: Fibronectin seems to play a very important role in the progression and invasion of bladder cancer. EDA, EDB, and IIICS domains of fibronectin are not expressed in the adult persons but they’re expressed in different cancers. The aim of this study is to investigate the mRNA of fibronectin in transitional carcinoma cells (TCC of bladder to study these domains. Methods: A total of 20 patients with known bladder cancer were studied. Two of them excluded since their excised tissues were not enough for both the pathological examination and RNA study. Another 20 (control group were normal volunteers who needed bladder operations. The excised tissue was immediately transferred to RNAlater (Ambion,TX. RNA was extracted via RNAWIZ (Ambion, TX. cDNA was made via RevertAid First Strand cDNA Synthesis Kit (Fermentas. PCR of the cDNAs was performed using primers for EDA, EDB, and IIICS (Eurogentec,Belgium. Results: For the first time, we present the expression of the oncofetal fibronectin mRNA in the transitional cell carcinoma of bladder. The high grade muscle invasive (G3T2 tumor, expressed ED-A, ED-B, and IIICS. Expression of ED-A, ED-B, and IIICS was confirmed in the two patients with G3T1 TCC. The four patients with G2Ta and G3Ta expressed both ED-A and ED-B. The four patients with G1T1 tumor expressed ED-A only, similar to the nine patients with G1Ta tumor. None of the normal volunteers expressed the oncofetal extra domains. The sensitivity of ED-A positive fibronectin RNA for detecting TCC of any kind is 100%, and of ED-B was only 35%. The specificity of ED-B positive fibronectin RNA for the high grade TCC is 100%. Conclusion: ED-A, ED-B, and IIICS could be used as useful markers for the diagnosis and following up of bladder carcinoma. Keywords: Transitional Cell Carcinoma, bladder cancer, fibronectin, RT-PCR, oncofetal.

  1. Patient-Centered Care Transition for Patients Admitted through the ED: Improving Patient and Employee Experience

    Directory of Open Access Journals (Sweden)

    Andrea Algauer BSN, RN

    2015-05-01

    Full Text Available With increasing wait times in emergency departments (ED across America, there is a need to streamline the inpatient admission process in order to decrease wait times and more important, to increase patient and employee satisfaction. One inpatient unit at New York-Presbyterian Weill Cornell Medical Center initiated a program to help expedite the inpatient admission process from the ED. The goal of the ED Bridge program is to ease the patient's transition from the ED to an inpatient unit by visiting the patient in the ED and introducing and setting expectations for the inpatient environment (i.e. telemetry alarms, roommates, hourly comfort rounds. Along with improving the patient experience, this program intends to improve the collaboration between ED nurses and inpatient nurses. With the continued support of our nurse management, hospital administrators and most important, our staff, this concept is aimed to increase patient satisfaction scores and subsequently employee satisfaction.

  2. Patient-Centered Care Transition for Patients Admitted through the ED: Improving Patient and Employee Experience.

    Science.gov (United States)

    Algauer, Andrea; Rivera, Stephanie; Faurote, Robert

    2015-05-01

    With increasing wait times in emergency departments (ED) across America, there is a need to streamline the inpatient admission process in order to decrease wait times and more important, to increase patient and employee satisfaction. One inpatient unit at New York-Presbyterian Weill Cornell Medical Center initiated a program to help expedite the inpatient admission process from the ED. The goal of the ED Bridge program is to ease the patient's transition from the ED to an inpatient unit by visiting the patient in the ED and introducing and setting expectations for the inpatient environment (i.e. telemetry alarms, roommates, hourly comfort rounds). Along with improving the patient experience, this program intends to improve the collaboration between ED nurses and inpatient nurses. With the continued support of our nurse management, hospital administrators and most important, our staff, this concept is aimed to increase patient satisfaction scores and subsequently employee satisfaction.

  3. SED-ED, a workflow editor for computational biology experiments written in SED-ML.

    Science.gov (United States)

    Adams, Richard R

    2012-04-15

    The simulation experiment description markup language (SED-ML) is a new community data standard to encode computational biology experiments in a computer-readable XML format. Its widespread adoption will require the development of software support to work with SED-ML files. Here, we describe a software tool, SED-ED, to view, edit, validate and annotate SED-ML documents while shielding end-users from the underlying XML representation. SED-ED supports modellers who wish to create, understand and further develop a simulation description provided in SED-ML format. SED-ED is available as a standalone Java application, as an Eclipse plug-in and as an SBSI (www.sbsi.ed.ac.uk) plug-in, all under an MIT open-source license. Source code is at https://sed-ed-sedmleditor.googlecode.com/svn. The application itself is available from https://sourceforge.net/projects/jlibsedml/files/SED-ED/.

  4. Analysis of closed malpractice medical claims against Taiwanese EDs: 2003 to 2012.

    Science.gov (United States)

    Wu, Kuan-Han; Wu, Chien-Hung; Cheng, Shih-Yu; Lee, Wen-Huei; Kung, Chia-Te

    2014-09-01

    The objective of the study is to examine the epidemiologic data of closed malpractice medical claims against emergency departments (EDs) in Taiwanese civil courts and to identify high-risk diseases. We conducted a retrospective study and reviewed the verdicts from the national database of the Taiwan judicial system that pertained to EDs. Between 2003 and 2012, a total of 63 closed medical claims were included. Seven cases (11.1%) resulted in an indemnity payment, 55.6% of the cases were closed in the district court, but appeals were made to the supreme court in 12 cases (19.1%). The mean incident-to-litigation closure time was 57.7 ± 26.8 months. Of the cases with indemnity paid, 5 cases (71.4%) were deceased, and 2 cases (28.6%) were gravely injured. All cases with indemnity paid were determined to be negligent by a medical appraisal. The gravely injured patients had more indemnity paid than deceased patients ($299800 ± 37000 vs $68700 ± 29300). The most common medical conditions involved were infectious diseases (27.0%), central nervous system bleeding (15.9%), and trauma cases (12.7%). It was also found that 71.4% of the allegations forming the basis of the lawsuit were diagnosis related. Emergency physicians (EPs) in Taiwan have similar medico-legal risk as American EPs, with an annual risk of being sued of 0.63%. Almost 90% of EPs win their cases but spend 58 months in litigation, and the mean indemnity payment was $134738. Cases with indemnity paid were mostly categorized as having diagnosis errors, with the leading cause of error as failure to order an appropriate diagnostic test. Copyright © 2014 Elsevier Inc. All rights reserved.

  5. Influence of disciplines of area «Computer science» on the process of forming professional competence of bachelors of pedagogical education of the profile «Mathematics»

    Directory of Open Access Journals (Sweden)

    Николай Иорданович Бордуков

    2012-06-01

    Full Text Available Article is devoted the analysis of preparation in the field of computer science of bachelors in a direction Pedagogical education of a profile of Mathematician on purpose to define the requirements shown by the standard to quality of preparation of students of the given direction.

  6. Vardenafil improves sexual function and treatment satisfaction in couples affected by erectile dysfunction (ED): a randomized, double-blind, placebo-controlled trial in PDE5 inhibitor-naïve men with ED and their partners.

    Science.gov (United States)

    Edwards, David; Hackett, Geoff; Collins, Owen; Curram, John

    2006-11-01

    Erectile dysfunction (ED) is a common condition with diverse sequelae affecting men and their women partners. The FINDER study aimed to evaluate the efficacy and tolerability of the phosphodiesterase type-5 (PDE5) inhibitor, vardenafil, in a broad population of PDE5-naïve men with ED of different etiologies and severity and included their partners' assessments of treatment with vardenafil. Men with ED (N = 260) were randomized to receive either vardenafil or placebo in a multicenter, flexible-dose study. Primary efficacy variables were patients' responses to the Global Assessment Question (GAQ), and Sexual Encounter Profile questions 2 and 3 (SEP2 and SEP3). Compared with placebo, vardenafil significantly improved rates of successful "Yes" responses to SEP3 ("Did your erection last long enough for you to have successful intercourse?") (49% placebo vs. 78% vardenafil at last period carried forward [LPCF]; P < 0.0001), SEP2 ("Were you able to insert your penis into your partner's vagina?") (65% placebo vs. 85% vardenafil at LPCF; P < 0.0001), and GAQ (36% placebo vs. 83% vardenafil at last observation carried forward; P < 0.0001). In addition, patients' and their partners' Treatment Satisfaction Scale (TSS) scores were statistically significantly improved across each of the TSS domains (satisfaction with orgasm, ease with erection, confidence, pleasure, erectile function satisfaction, and satisfaction with medication) in the vardenafil group compared with the placebo group. Vardenafil improved sexual function to the extent that both patients and their partners expressed a considerable and agreed level of satisfaction with treatment.

  7. Nine years of DentEd--a global perspective on dental education.

    Science.gov (United States)

    Reynolds, P A; Eaton, K A; Paganelli, C; Shanley, D

    2008-08-23

    This paper describes the three successive and successful DentEd projects, funded by the European Union, that established a productive thematic network which identified common content within the dental curriculum. It then developed an agreed professional profile, with a defined set of competences and a modular curriculum for all new dental graduates based on the European Credit Transfer System and trends in learning and assessment. The three phases took nine years to complete. Phase one investigated all aspects of dental undergraduate education and included over 30 visits to different dental schools by teams of dental educators. Phase two built on this work and included further visits to dental schools. Phase three refined the competency framework that had been developed in phase two and culminated in a global dental conference which finalised position papers on all aspects of dental education. The work and recommendations of the ICT in dental education group are considered in detail in the paper. The projects provided the stimulus for a number of European and international collaborations, including the web-based International Federation of Dental Education and Associations (IFDEA) Knowledge Centre and the International Virtual Dental School (IVIDENT), both of which aim to make increasingly sophisticated ICT-based educational material available worldwide and to promote international understanding.

  8. X-linked anhidrotic ectodermal dysplasia (ED1 in men, mice, and cattle

    Directory of Open Access Journals (Sweden)

    Drögemüller Cord

    2003-06-01

    Full Text Available Abstract Ectodermal dysplasias are a large group of rare genetic disorders characterized by impaired development of hair, teeth, and eccrine glands in humans, mice, and cattle. Here, we review the cloning, mutation analyses, and functional studies of the known causative genes for the X-chromosomal anhidrotic ectodermal dysplasia (ED1 in these species. Mutations in the ectodysplasin 1 (ED1 gene are responsible for X-linked anhidrotic ectodermal dysplasia. The ED1 gene encodes a signaling molecule of the tumor necrosis factor family that is involved in development of ectodermal appendages. The bovine disorder may serve as an animal model for human ED1.

  9. A Preliminary Examination of Loss of Control Eating Disorder (LOC-ED) in Middle Childhood

    Science.gov (United States)

    Matherne, Camden E.; Tanofsky-Kraff, Marian; Altschul, Anne M.; Shank, Lisa M.; Schvey, Natasha A.; Brady, Sheila M.; Galescu, Ovidiu; Demidowich, Andrew P.; Yanovski, Susan Z.; Yanovski, Jack A.

    2015-01-01

    Loss of Control Eating Disorder (LOC-ED) has been proposed as a diagnostic category for children 6–12y with binge-type eating. However, characteristics of youth with LOC-ED have not been examined. We tested the hypothesis that the proposed criteria for LOC-ED would identify children with greater adiposity, more disordered eating attitudes, and greater mood disturbance than those without LOC-ED. Participants were 251 youth (10.29y ± 1.54, 53.8% female, 57.8 % White, 35.5% Black, 2.0% Asian, 4.8% Hispanic, 53.0% overweight). Youth were interviewed regarding eating attitudes and behaviors, completed questionnaires to assess general psychopathology, and underwent measurements of body fat mass. Using previously proposed criteria for LOC-ED, children were classified as LOC-ED (n = 19), LOC in the absence of the full disorder (subLOC, n = 33), and youth not reporting LOC (noLOC, n = 199). LOC-ED youth had higher BMIz (p = 0.001) and adiposity (p = 0.003) and reported greater disordered eating concerns (p disordered eating attitudes (p = 0.02). SubLOC youth had greater disordered eating concerns (p disordered eating cognitions and anthropometric measures compared to youth without LOC-ED. Longitudinal studies are needed to determine if those with LOC-ED are at particularly increased risk for progression of disordered eating and excess weight gain. PMID:25913008

  10. 8 Different approaches needed to manage ED demand among different age-groups.

    Science.gov (United States)

    Rimmer, Melanie; Ablard, Suzanne; O'Keeffe, Colin; Mason, Suzanne

    2017-12-01

    A variety of interventions have been proposed to manage rising demand for Emergency and Urgent Care, described by an NHS England review as unsustainable in the long term. However it is unlikely that any suggested approach will be equally suitable for the diverse population of ED users.We aimed to understand the patterns of demand amongst different types of patients attending ED. We also sought to understand the intended and unintended effects of demand management initiatives. Our study combined insights from routine data, a survey of ED patients, and qualitative interviews with ED staff. This paper describes the results of our analysis of the interviews. We conducted semi-structured interviews with 25 ED and Urgent Care Centre staff across 7 hospital sites in Yorkshire and Humber between 25 April and 11 July 2016. The interview topic guide asked about 4 broad areas; job role, description of patients and their impact on demand, description of inappropriate attendance, and current/future initiatives to deal with rising demand. Interviews were transcribed verbatim and analysed using framework analysis. We analysed the results to identify groups of patients with different patterns of use of ED services. We also explored ED staff experiences of demand management initiatives, and their suggestions for future initiatives. Although we did not ask specifically about patients' age, our analysis revealed that ED staff categorised attenders as children and young people, working age people, and older people. These groups had different reasons for attendance, different routes to the ED, different rate of non-urgent attendance, and different issues driving demand. Staff also described variation in the time taken to treat patients of different ages, with the oldest and youngest patients described as requiring the most time.There was no consensus amongst staff about the effectiveness of initiatives for managing demand. A strikingly wide variety of initiatives were mentioned

  11. Flat-on ambipolar triphenylamine/C60 nano-stacks formed from the self-organization of a pyramid-sphere-shaped amphiphile† †Electronic supplementary information (ESI) available: 1H and 13C NMR spectra, TGA, DSC, XRD, simulated ED patterns, UV-Vis spectra, reduction and oxidation cyclic voltammetry curves. See DOI: 10.1039/c5sc04242a Click here for additional data file.

    Science.gov (United States)

    Liang, Wei-Wei; Huang, Chi-Feng; Wu, Kuan-Yi; Wu, San-Lien; Chang, Shu-Ting; Cheng, Yen-Ju

    2016-01-01

    A giant amphiphile, which is constructed with an amorphous nano-pyramid (triphenylamine, TPA) and a crystalline nano-sphere (C60), was synthesized. Structural characterization indicates that this pyramid-sphere-shaped amphiphile (TPA–C60) forms a solvent-induced ordered phase, in which the two constituent units self-assemble into alternating stacks of two-dimensional (2D) TPA and C60 nano-sheets. Due to the complexity of the molecular structure and the amorphous nature of the nano-pyramid, phase formation was driven by intermolecular C60–C60 interactions and the ordered phase could not be reformed from the TPA–C60 melt. Oriented crystal arrays of TPA–C60, which contain flat-on TPA/C60 nano-stacks, can be obtained via a PDMS-assisted crystallization (PAC) technique. The flat-on dual-channel supramolecular structure of TPA–C60 delivered ambipolar and balanced charge-transport characteristics with an average μ e of 2.11 × 10–4 cm2 V–1 s–1 and μ h of 3.37 × 10–4 cm2 V–1 s–1. The anisotropic charge-transport ability of the pyramid-sphere-shaped amphiphile was further understood based on the lattice structure and the lattice orientation of TPA–C60 revealed from electron diffraction analyses. PMID:28660054

  12. The MAL-ED cohort study in Mirpur, Bangladesh.

    Science.gov (United States)

    Ahmed, Tahmeed; Mahfuz, Mustafa; Islam, Md Munirul; Mondal, Dinesh; Hossain, Md Iqbal; Ahmed, Am Shamsir; Tofail, Fahmida; Gaffar, Sm Abdul; Haque, Rashidul; Guerrant, Richard L; Petri, William A

    2014-11-01

    The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) study site in Bangladesh is located in the capital city of Dhaka in an urban slum that has one of the highest population densities in the world. The site is in the Bauniabadh area of Mirpur, Dhaka. A typical squatter settlement, the average family size of households in Mirpur Bauniabadh is 4.5, with 48% females. About 20% of households have a monthly income of only US$62. About 30% of mothers never attended school, and only 3% obtained secondary school education. The majority of the people are day laborers, garment workers, and transport workers. About 72% of caregivers always wash their hands after helping the child defecate and 6.6% never wash their hands. The diarrheal attack rate for Mirpur is 4.69 episodes per child per year. The study site is representative of a typical urban slum of Dhaka city in terms of demographics, socioeconomic status, and general health indicators. © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  13. On E.D. Jones' MICROCOSMOLOGY

    Energy Technology Data Exchange (ETDEWEB)

    Noyes, H. Pierre

    2003-01-08

    By taking seriously the limits on observability which come from combining relativistic quantum mechanics with general relativity, Ed Jones has shown that the current measurements of the cosmological constant density {Omega}{sub {Lambda}} {approx} 0.7 imply that the temperature scale at which it becomes possible to discuss cosmological models is {approx} 5 Tev (5.8 x 10{sup 16} K). This is self-consistent with the assumption that the number of Planck masses which make some sort of ''phase transition'' to this state is N{sub Pk} {approx} 4 x 10{sup 61}. We review Jones' argument and the bit-string physics calculation which gives the baryon-photon ratio at nucleosynthesis as {approx} 2/256{sup 4}, the dark matter-baryon ratio as {approx} 12.7, and hence {Omega}{sub m} {approx} 0.3, in agreement with current observations. Accepting these values for the two energy densities {Omega}{sub {Lambda}} + {Omega}{sub m} {approx} 1 in accord with recent analyses of fluctuations in the CMB showing that space is flat to about 6%. We conclude that experiments with particle accelerators in the 5-10 Tev range must either show that current theory can adequately describe the currently observed structure of our universe or force us to revise our ideas about physics at a very fundamental level.

  14. Spazio, movimento, prospettiva ed empatia: un prototipo di videogame didattico

    Directory of Open Access Journals (Sweden)

    Pio Alfredo Di Tore

    2014-09-01

    Full Text Available Questo lavoro presenta la cornice teorica che sta alla base della progettazione di un videogame didattico pensato per valutare le abilità di perspective taking (capacità di adottare la prospettiva altrui e di mental rotation (rotazione mentale dei giocatori. Lo studio mira a rilevare come tali abilità siano coinvolte nella relazione empatica e a verificarne le implicazioni in campo educativo. Il lavoro adotta la definizione di empatia riconducibile ad Alain Berthoz ed alla teoria spaziale dell’empatia qui presentata con i relativi sistemi di riferimento spaziale. È inoltre fornita una rapida revisione della letteratura sulla rappresentazione dello spazio nel bambino e sulla rappresentazione dello spazio nel gioco (su base visiva. Infine, il lavoro descrive il prototipo di gioco – realizzato presso l’Università di Salerno – in cui il giocatore si trova alle prese con tre differenti compiti di cui due progettati per misurare le abilità di perspective taking mentre il terzo è calibrato sulle abilità di mental rotation.

  15. Home modification to prevent falls by older ED patients.

    Science.gov (United States)

    Gerson, Lowell W; Camargo, Carlos A; Wilber, Scott T

    2005-05-01

    This trial was conducted at 11 EDs to test the effectiveness of distributing fall prevention information to patients 65 years or older. Intervention patients were given 2 brochures and received a reminder call 2 weeks later. All patients were called at 1 month and asked if they made home safety modifications. Three hundred ninety-seven patients were enrolled (118 control, 279 intervention). Seventy-six percent had complete follow up interviews. Nine percent of control and 8% of intervention patients reported a home modification (95% confidence interval on difference, -8.1% to 5.5%). Patients who fell in the prior year had a 2.0 increased odds (95% confidence interval, 0.8-4.6) of making a home modification. The similar home modification rates in the 2 study groups suggest that even minimum discussion (eg, the informed consent procedure) may increase patients' fall prevention activities. The stronger association in patients who fell suggests that a targeted program may have added benefit.

  16. Spirometrie v prostředí LabVIEW

    OpenAIRE

    Pernicová, Lenka

    2010-01-01

    Tato bakalářská práce se zabývá funkčním vyšetřením plic – spirometrií. Skládá se ze dvou základních částí. V první části je důležité seznámit se s jednotlivými metodami funkčního vyšetření plic. Na základě důkladného prostudování parametrů popisujících funkci plic a zaměření se na spirometrickou křivkou, bylo možné přejít k druhé části této práce, tzn. k realizaci spirometru v grafickém prostředí LabVIEW. Vytvořený virtuální přístroj nám umožňuje zobrazení spirometrické křivky, následnou ana...

  17. Alprostadil plus Vacuum (VITARUM in severe erectile dysfunction (ED

    Directory of Open Access Journals (Sweden)

    Franco Mantovani

    2017-06-01

    Full Text Available Objectives: Severe erectile dysfunction (ED is not uncommon, as can be seen from the epidemiological literature, and there are several possible causes, which are not always known, or leastways evident. Having ascertained the ineffectiveness, intolerance to or rejection of pharmacological aids, the option of prosthetic surgery remains, but before this, it may be wise when feasible to use Alprostadil cream in association with Vacuum device. Material and methods: 12 patients, aged between 55 and 65 years, with severe erectile dysfunction without palpable cavernous fibrosis, were instructed to self-insert into the urethral meatus, 3 mg of Alprostadil cream, sufficient to make it easy to place the Vacuum device over the penis. Results: In the cases observed, the preliminary use of Alprostadil cream fast produced an erection with enough rigidity to place the Vacuum. A sufficient erection was maintained, obviously using an elastic ring at the base of the penis, to achieve penetration. The reproducibility of the use of Alprostadil cream with Vacuum device was then confirmed at home, to the satisfaction of the patients.

  18. Ready-JET-Go: Split Flow Accelerates ED Throughput.

    Science.gov (United States)

    Bish, Peter A; McCormick, Mary A; Otegbeye, Mojisola

    2016-03-01

    Struggling to keep up with The Centers for Medicare and Medicaid Services out-patient throughput metrics, an adult emergency department serving Burlington and Camden Counties, New Jersey, sought to redefine its care delivery model by adopting the patient segmentation initiatives of the split-flow process of patient care. A multidisciplinary team of ED clinicians collaboratively defined the patient segmentation criteria. A joint assessment team approach to patient care was instituted. A 3-pronged approach was adopted to prepare staff for the patient care changes in line with an existing framework specified by the Institute of Medicine. Simulation and queuing analyses were used to estimate the accompanying resource needs. Since implementing split flow, the emergency department has witnessed significant improvements in patient throughput and patient satisfaction, despite a sustained 10% increase in patient volumes after split-flow implementation. The median length of stay for discharged patients and the door-to-diagnostic evaluation time are now down to 112 minutes and 30 minutes, respectively, compared with pre-split-flow values of 192 minutes and 72 minutes, respectively. Working collaboratively with all stakeholders to define the right patient care delivery model, combined with an understanding of the right resource assignments to optimally support that care delivery model, an emergency department can institute cost-effective changes to realize and sustain significant patient throughput improvements. Copyright © 2016 Emergency Nurses Association. Published by Elsevier Inc. All rights reserved.

  19. Book Review: Digital Forensic Evidence Examination (2nd ed.

    Directory of Open Access Journals (Sweden)

    Gary Kessler

    2010-06-01

    Full Text Available Cohen, F. (2010. Digital Forensic Evidence Examination (2nd ed.. Livermore, CA: ASP Press. 452 pages, ISBN: 978-1-878109-45-3, US$79.Reviewed by Gary C. Kessler, Gary Kessler Associates & Edith Cowan University (gck@garykessler.netOn the day that I sat down to start to write this review, the following e-mailcame across on one of my lists:Person A and Person B write back and forth and create an email thread. Person A then forwards the email to Person C, but changes some wording in the email exchange between A & B. What is the easiest way (and is it even possible to find out when that earlier email message was altered before sent to Person C?Before you try to answer these questions, read Fred Cohen's Digital Forensic Evidence Examination. His book won't actually tell you how to answer these questions but it will help you understand the difficulty in even trying to answer them with any level of certainty.(see PDF for full review

  20. Verbo come elemento della frase in friulano ed in frances

    Directory of Open Access Journals (Sweden)

    David Bizjak

    2003-12-01

    Full Text Available Il presente lavoro e dedicato a una parte della sfera del verbo nel friulano  lettera­ rio della seconda meta del ventesimo secolo, alla perifrasi verbale e alla locuzione verbale. Nella definizione della perifrasi verbale (PV ho seguito il modello dei lin­ guisti spagnoli Javier Garcia Gonzales, Fernandez de Castro e Leonard Gomez Torrego, essendo ilpunto di partenza ilmio postulato che la PV rappresenti in friu­ lano una categoria grammaticale a parte o, almeno, una categoria in via di gramma­ ticalizzazione. Parallelamente alla situazione in friulano osservo quella nel francese scritto contemporaneo, con lo scopo di constatare delle eventuali somiglianze e diffe­ renze. Tenendo in considerazione la realta linguistica nella regione Friuli-Venezia Giulia, dove le interferenze fra l'italiano, il friulano ed il veneto sono tali che un non-friulanofono non riesce facilmente a distinguere quando si tratta di un sintag­ ma di origine friulana e quando di un calco sintattico sull'italiano, sembra oppor­ tuno, in numerosi casi, confrontare ilsintagma friulano e quello francese anche con la variante corrispondente in italiano letterario moderno; inoltre, nel capitolo in cui sono trattati i cosiddetti tempi bicomposti, vengono citati alcuni esempi nelle diver­ se varieta venete.

  1. Etica ed evoluzionismo: la proposta di Marc Hauser

    Directory of Open Access Journals (Sweden)

    Irene Pilloni

    2013-11-01

    Full Text Available Le recenti scoperte nell’ambito della psicologia evoluzionistica potrebbero offrire una risposta al dibattito sull’origine evoluzionistica della facoltà morale dell’Homo sapiens. In passato, il tentativo di spiegare il comportamento morale a partire dalla teoria dell’evoluzione è stato intrapreso dal padre fondatore dell’evoluzionismo Charles Darwin, successivamente da T.H. Huxley e da H. Spencer e infine dal sociobiologo E. Wilson a metà degli anni ‘70 del Novecento. Oggi questa impresa è stata ereditata dallo psicologo evoluzionista Marc Hauser, le cui indagini prendono avvio da un’analogia tra facoltà morale e facoltà linguistica. Questa analogia gli consente di affermare che la pluralità di codici morali adottati dagli uomini nelle differenti culture dipende da un numero limitato di principi morali, nello stesso modo in cui la varietà di lingue con cui gli uomini si esprimono, dipende da un numero limitato di principi linguistici universali. Dunque, sembrerebbe che l’evoluzione biologica abbia plasmato dei principi morali universali e uniformi che si presentano costanti in tutti gli uomini a prescindere dalla loro appartenenza culturale. Come vadano intesi i principi morali universali e quale rapporto intercorre tra di essi e i vari codici morali sarà l’argomento di questo saggio, il quale tenterà di analizzare la proposta di Marc Hauser all’interno della cornice dei rapporti tra etica ed evoluzionismo.

  2. Sappiamo davvero come far apprendere? Credenza ed evidenza empirica.

    Directory of Open Access Journals (Sweden)

    Roberto Trinchero

    2013-08-01

    Full Text Available “I ragazzi con più stimoli apprendono di più e meglio di quelli sottoposti a meno stimoli!”, “In questa scuola non possiamo fare didattica attiva perché non abbiamo i laboratori!”, “I ragazzi imparano meglio se li si lascia sperimentare e costruire i concetti da soli!”, “La lezione frontale? Ormai è una strategia didattica superata!”, “Se hai capito il concetto una volta, poi lo saprai applicare sempre!”, “I ragazzi imparano meglio quando fanno lavori di gruppo!”. Quante volte avete sentito insegnanti ed educatori pronunciare queste frasi? Ma cosa dice la ricerca in proposito? Queste sono solo credenze o hanno davvero un fondamento empirico? Il presente articolo intende fornire alcune evidenze per supportare, confutare, chiarire le condizioni di validità degli asserti suddetti. Le evidenze sono tratte dalla ricerca sul funzionamento della mente e dalle meta-analisi che si sono occupate di sintetizzare i principali studi empirici riguardanti l’impatto di varie strategie didattiche sull’apprendimento dei soggetti in formazione.

  3. Digitalization in roll forming manufacturing

    Science.gov (United States)

    Sedlmaier, A.; Dietl, T.; Ferreira, P.

    2017-09-01

    Roll formed profiles are used in automotive chassis production as building blocks for the body-in-white. The ability to produce profiles with discontinuous cross sections, both in width and in depth, allows weight savings in the final automotive chassis through the use of load optimized cross sections. This has been the target of the 3D Roll Forming process. A machine concept is presented where a new forming concept for roll formed parts in combination with advanced robotics allowing freely positioned roll forming tooling in 3D space enables the production of complex shapes by roll forming. This is a step forward into the digitalization of roll forming manufacturing by making the process flexible and capable of rapid prototyping and production of small series of parts. Moreover, data collection in a large scale through the control system and integrated sensors lead to an increased understanding of the process and provide the basis to develop self-optimizing roll forming machines, increasing the productivity, quality and predictability of the roll-forming process. The first parts successfully manufactured with this new forming concept are presented.

  4. Hearing of Mr. Francois Roussely, President of EdF; Audition de M. Francois Roussely, President d'EdF

    Energy Technology Data Exchange (ETDEWEB)

    Roussely, F. [Electricite de France (EDF), 75 - Paris (France)

    2005-07-01

    This document is the proceedings of the hearing of F. Roussely, President of Electricite de France (EdF), at the commission of economic affairs of the French house of commons, about the advisability of the construction of the EPR (European pressurized reactor) demonstration plant and about its possible financing by EdF. In a first part, F. Roussely recalls the European context of deregulation of energy markets and its impact of the French electric power industry (opening of the French market, industrial and social actions of EdF, need of a new generation of nuclear reactor, preservation of EdF's energy mix, warranty of public utility, un-bundling between energy trade and distribution, EdF's turnover and profitability, EdF's foreign daughter companies). In a second part, F. Roussely answers a series of questions asked by the different members of the commission concerning the different points presented in the first part. (J.S.)

  5. Depth profile investigation of β-FeSi{sub 2} formed in Si(1 0 0) by high fluence implantation of 50 keV Fe ion and post-thermal vacuum annealing

    Energy Technology Data Exchange (ETDEWEB)

    Lakshantha, Wickramaarachchige J.; Kummari, Venkata C.; Reinert, Tilo; McDaniel, Floyd D. [Ion Beam Modification and Analysis Laboratory, Department of Physics, University of North Texas, 1155 Union Circle #311427, Denton, TX 76203 (United States); Rout, Bibhudutta, E-mail: bibhu@unt.edu [Ion Beam Modification and Analysis Laboratory, Department of Physics, University of North Texas, 1155 Union Circle #311427, Denton, TX 76203 (United States); Center for Advanced Research and Technology, University of North Texas, 3940 North Elm Street, Denton, TX 76207 (United States)

    2014-08-01

    A single phase polycrystalline β-FeSi{sub 2} layer has been synthesized at the near surface region by implantation in Si(1 0 0) of a high fluence (∼10{sup 17} atoms/cm{sup 2}) of 50 keV Fe ions and subsequent thermal annealing in vacuum at 800 °C. The depth profile of the implanted Fe atoms in Si(1 0 0) were simulated by the widely used transportation of ions in matter (TRIM) computer code as well as by the dynamic transportation of ions in matter code (T-DYN). The simulated depth profile predictions for this heavy ion implantation process were experimentally verified using Rutherford Backscattering Spectrometry (RBS) and X-ray Photoelectron Spectroscopy (XPS) in combination with Ar-ion etching. The formation of the β-FeSi{sub 2} phase was monitored by X-ray diffraction measurements. The T-DYN simulations show better agreement with the experimental Fe depth profile results than the static TRIM simulations. The experimental and T-DYN simulated results show an asymmetric distribution of Fe concentrated more toward the surface region of the Si substrate.

  6. Eloise Greenfield (Profile).

    Science.gov (United States)

    Bishop, Rudine Sims

    1997-01-01

    Profiles Eloise Greenfield. Reveals that Greenfield's early love of music echoes in both the form and content of her poetry and prose. Notes that her poems are marked by strong rhythms, expressions of emotion, and a strong sense of children, their voices, and the waystations on their journey through life. (SR)

  7. Cross-Sectional Information on Pore Structure and Element Distribution of Sediment Particles by SEM and EDS

    Directory of Open Access Journals (Sweden)

    Minghong Chen

    2017-01-01

    Full Text Available The interaction between pollutants and sediment particles often occurs on the particle surface, so surface properties directly affect surface reaction. The physical and chemical processes occurring on sediment particle surfaces are microscopic processes and as such need to be studied from a microscopic perspective. In this study, field emission scanning electron microscopy (SEM and energy dispersive X-ray spectrometer (EDS were adopted to observe and analyze the pore structure and element distribution of sediment particles. In particular, a special method of sample preparation was used to achieve the corresponding cross-sectional information of sediment particles. Clear images of a particle profile and pore microstructure were obtained by high-resolution SEM, while element distribution maps of sediment particles were obtained by EDS. The results provide an intuitive understanding of the internal microenvironment and external behavior of sediment particles, in addition to revealing a significant role of pore microstructure in the adsorption and desorption of pollutants. Thus, a combination of different experimental instruments and observation methods can provide real images and information on microscopic pore structure and element distribution of sediment particles. These results should help to improve our understanding of sediment dynamics and its environmental effects.

  8. Lipid Profile Pattern amongst Type 2 DM subjects with Erectile ...

    African Journals Online (AJOL)

    Objective:Dyslipidaemia in patientswith diabetesmellitus leads to atherosclerosis and this contributes to erectile dysfunction (ED). This study set out to characterize the lipid profile pattern in diabetic patients with erectile dysfunction. Subject andMethods:Aprospective, cross sectional study carried out at the diabetes clinic of ...

  9. Comparisons between the Nottingham Health Profile and the Short Form-36 for assessing the quality of life of community-dwelling elderly Comparação dos instrumentos de qualidade de vida Perfil de Saúde de Nottingham e Short Form-36 em idosos da comunidade

    Directory of Open Access Journals (Sweden)

    Christina D. C. M. Faria

    2011-10-01

    Full Text Available BACKGROUND: The aging population and associated high disability rates make the assessment of health-related quality of life (HRQOL a high priority for elderly people. OBJECTIVES: To compare the Brazilian versions of the Nottingham Health Profile (NHP and the Short Form Health Survey-36 (SF-36 regarding their measurement properties, such as, ceiling and floor effects, inter-rater/test-retest reliabilities, internal consistency, and the associations between the total scores and those of similar domains. METHODS: The NHP and the SF-36 were randomly administered through interviews to 40 community-dwelling elderly (mean age 70.57; SD=7.42 years. The scores of the five similar domains of the NHP and the SF-36, in percentages, were compared: Energy level/Vitality (EL/V, pain, emotional reactions/mental health (EM/MH, social isolation/social functioning (SI/SF, and physical mobility/physical functioning (PA/PF. Descriptive statistics, Spearman Correlation Coefficient, a-Cronbach, and Intraclass Correlation Coefficients (ICCs were used for analyses (a=0.05. RESULTS: Both instruments demonstrated ceiling and floor effects for all similar domains, however the NHP showed, on average, higher scores for individual domains and total scores, as well as, floor effects for the SI domain. The internal consistency (NHP=0.86; SF-36=0.80, the inter-rater reliability (NHP=0.99; SF-36=0.96 and the test-retest reliability (NHP=0.94; SF-36=0.83 were considered adequate. Positive and statistically significant correlations were found between all similar domains (p≤0.01; 0.41≤rs≤0.70, except for those related to EL and vitality (rs=0.21;p=0.19. CONCLUSIONS: The SF-36 demonstrated to be more adequate regarding the ceiling and floor effects, whereas the NHP presented a higher internal consistency and reliability levels. These findings should be considered for selecting instruments for the assessment of HRQOL of community-dwelling elderly.CONTEXTUALIZAÇÃO: O

  10. A Disability Studies in Education Analysis of the edTPA through Teacher Candidate Perspectives

    Science.gov (United States)

    Bacon, Jessica; Blachman, Sheila

    2017-01-01

    This analysis of the Special Education edTPA is written by two professors who co-taught a student teaching seminar at one institution and supported the first groups of teacher candidates required to submit the edTPA for certification in New York State. Data were gathered over three semesters and included open-ended student surveys, student…

  11. Multiple Intelligence and Digital Learning Awareness of Prospective B.Ed Teachers

    Science.gov (United States)

    Gracious, F. L. Antony; Shyla, F. L. Jasmine Anne

    2012-01-01

    The present study Multiple Intelligence and Digital Learning Awareness of prospective B.Ed teachers was probed to find the relationship between Multiple Intelligence and Digital Learning Awareness of Prospective B.Ed Teachers. Data for the study were collected using self made Multiple Intelligence Inventory and Digital Learning Awareness Scale.…

  12. A Review of "Older, Wiser, Sexually Smarter: 30 Sex Ed Lessons for Adults Only"

    Science.gov (United States)

    Garrity, Joan Mogul

    2010-01-01

    While virtually all sex ed curricula are designed to be used with children, teens and young adults, "Older, Wiser, Sexually Smarter: 30 Sex Ed Lessons for Adults Only" ([C] 2009, Planned Parenthood of Greater Northern New Jersey) offers lessons to help participants fully embrace the possibility of sexual pleasure and intimacy from mid-life through…

  13. Is There a Future for Teacher Ed Curriculum? An Answer from History and Moral Philosophy

    Science.gov (United States)

    Null, J. Wesley

    2008-01-01

    Is there a future for teacher ed "curriculum"? The author contends that he is not sure if there is a future for teacher ed curriculum, but if such a future is to exist, the answer will come only from history and moral philosophy. In this article, the author opines that individuals cannot make good decisions about the future of teacher ed…

  14. Does routine symptom screening with ESAS decrease ED visits in breast cancer patients undergoing adjuvant chemotherapy?

    Science.gov (United States)

    Barbera, L; Sutradhar, R; Howell, D; Sussman, J; Seow, H; Dudgeon, D; Atzema, C; Earle, C; Husain, A; Liu, Y; Krzyzanowska, M K

    2015-10-01

    In 2007, the provincial cancer agency in Ontario, Canada initiated a wide-scale program to screen for symptoms in the cancer population using the Edmonton Symptom Assessment Scale (ESAS). The purpose of this study is to evaluate the impact of screening with ESAS on emergency department (ED) visit rates in women with breast cancer receiving adjuvant chemotherapy. This retrospective cohort study used linked administrative health care data from across the province of Ontario, Canada. The cohort included all women aged ≥18 who were diagnosed with stage I-III breast cancer between January 2007 and December 2009 and received adjuvant chemotherapy within 6 months of diagnosis. Using an adjusted recurrent event model, we examined the association of screening with ESAS at a clinic visit on the ED visit rate. The relative rate of ED visits was 0.57 when prior ESAS screening occurred compared to when it did not. The relative rate of ED visits was 0.83 when the prior number of ESAS screens was modeled as a continuous variable. Alternatively stated, the rate of ED visits was 43 % lower among patients previously screened with ESAS compared to those not previously screened. For each additional prior ESAS assessment, there was a 17 % decreased rate of ED visits. Our results demonstrate that screening with ESAS is associated with decreased ED visits. To our knowledge, this is the first report on the effectiveness of routinely documenting a patient reported outcome on ED visits, in a real-world setting.

  15. Book Review: John M. Hobson and Leonard Seabrooke (2007) (eds) Everyday Politics of the World Economy

    DEFF Research Database (Denmark)

    Strange, Michael Stewart

    2009-01-01

    Book Review: John M. Hobson and Leonard Seabrooke (2007) (eds) Everyday Politics of the World Economy (Cambridge: Cambridge University Press), 254pp. Udgivelsesdato: 2009......Book Review: John M. Hobson and Leonard Seabrooke (2007) (eds) Everyday Politics of the World Economy (Cambridge: Cambridge University Press), 254pp. Udgivelsesdato: 2009...

  16. Mental Health and Academic Achievement among M.Ed. Students in Kerala

    Science.gov (United States)

    Moradi Sheykhjan, Tohid; K., Rajeswari; Jabari, Kamran

    2017-01-01

    The present research endeavor was aimed to assess relationship between Mental Health and Academic Achievement among M.Ed. students in Kerala. The sample of the study consisted of 314 M.Ed. students in Kerala. The method used for the present study was survey method. Mental Health Status Scale (M.H.S. Scale) was used and the study used the total…

  17. Agro obacter pop rium m pular In mediate ndica r ed gen rice Ra ...

    African Journals Online (AJOL)

    SAM

    ed equally. e and Skoog, 2 remain perma e mediate ndica r. ¥, Swadesh. Plant Patholog unge Circular ge, 1/1, Suren hutosh Colleg ceived 27 Januar ansformation ing a binary ed. Various p. , bacterial co nd the conce equence an requency we ormation tech m tumefacien ry food crop population, h and proteom two third of t.

  18. Connecting Teachers and Ed-Tech Developers: Lessons from NYC's "Gap App" Program. Technical Appendices

    Science.gov (United States)

    Villavicencio, Adriana; Siman, Nina; Lafayette, Camille; Kang, David

    2016-01-01

    In 2011, with support from a federal Investing in Innovation grant, the NYC Department of Education launched Innovate NYC Schools. The initiative was designed to address two, related challenges to effectively integrating education technology (ed-tech) into classrooms: First, procurement of ed-tech tools is often hampered by a disconnect between…

  19. Connecting Teachers and Ed-Tech Developers: Lessons from NYC's "Gap App" Program. Report

    Science.gov (United States)

    Villavicencio, Adriana; Siman, Nina; Lafayette, Camille; Kang, David

    2016-01-01

    In 2011, with support from a federal Investing in Innovation grant, the NYC Department of Education launched Innovate NYC Schools. The initiative was designed to address two, related challenges to effectively integrating education technology (ed-tech) into classrooms: First, procurement of ed-tech tools is often hampered by a disconnect between…

  20. Electricity in south-east Asia. 2nd ed.

    Energy Technology Data Exchange (ETDEWEB)

    Breeze, P.

    2000-02-01

    The report updates one written in 1996, presenting statistics and information on the power market in Asia following the Asian economic crisis. It gives demand predictions and reviews the region's coal, oil, gas, hydropower, geothermal, wind and solar power resources. Country profiles giving a snapshot of the electricity sectors in each of the 12 following countries, predicted growth and the IPP programme: Cambodia, Indonesia, Laos, Malaysia, Myanmar, New Zealand, the Philippines, Singapore, Thailand and Vietnam. 120 tabs., 13 maps.

  1. A mechanistic nitrogen limitation model for CLM(ED)

    Science.gov (United States)

    Ali, A. A.; Xu, C.; McDowell, N. G.; Rogers, A.; Wullschleger, S. D.; Fisher, R.; Vrugt, J. A.

    2014-12-01

    Photosynthetic capacity is a key plant trait that determines the rate of photosynthesis; however, in Earth System Models it is either a fixed value or derived from a linear function of leaf nitrogen content. A mechanistic leaf nitrogen allocation model have been developed for a DOE-sponsored Community Land Model coupled to the Ecosystem Demography model (CLM-ED) to predict the photosynthetic capacity [Vc,max25 (μmol CO2 m-2 s-1)] under different environmental conditions at the global scale. We collected more than 800 data points of photosynthetic capacity (Vc,max25) for 124 species from 57 studies with the corresponding leaf nitrogen content and environmental conditions (temperature, radiation, humidity and day length) from literature and the NGEE arctic site (Barrow). Based on the data, we found that environmental control of Vc,max25 is about 4 times stronger than the leaf nitrogen content. Using the Markov-Chain Monte Carlo simulation approach, we fitted the collected data to our newly developed nitrogen allocation model, which predict the leaf nitrogen investment in different components including structure, storage, respiration, light capture, carboxylation and electron transport at different environmental conditions. Our results showed that our nitrogen allocation model explained 52% of variance in observed Vc,max25 and 65% variance in observed Jmax25 using a single set of fitted model parameters for all species. Across the growing season, we found that the modeled Vc,max25 explained 49% of the variability in measured Vc,max25. In the context of future global warming, our model predicts that a temperature increase by 5oC and the doubling of atmospheric carbon dioxide reduced the Vc,max25 by 5%, 11%, respectively.

  2. Accuracy of ED Bedside Ultrasound for Identification of Gallstones: Retrospective Analysis of 575 Studies

    Directory of Open Access Journals (Sweden)

    Scruggs, William

    2008-01-01

    Full Text Available Study Objective: To determine the ability of emergency department (ED physicians to diagnose cholelithiasis with bedside ultrasound. Methods: ED gallbladder ultrasounds recorded over 37 months were compared to radiology ultrasound interpretation. Results: Of 1,690 ED gallbladder ultrasound scans performed during this period, radiology ultrasound was performed in 575/1690 (34% cases. ED physician bedside interpretation was 88% sensitive [95% CI, 84-91] and 87% specific [95% CI, 82-91], while positive predictive value (PPV was 91% [88- 94%] and negative predictive value (NPV was 83% [78-87%], using radiology interpretation as the criterion reference. Conclusion: ED physician ultrasound of the gallbladder for cholelithiasis is both sensitive and specific.

  3. High-Resolution Macromolecular Structure Determination by MicroED, a cryo-EM Method

    Science.gov (United States)

    Rodriguez, J.A.; Gonen, T.

    2017-01-01

    Microelectron diffraction (MicroED) is a new cryo-electron microscopy (cryo-EM) method capable of determining macromolecular structures at atomic resolution from vanishingly small 3D crystals. MicroED promises to solve atomic resolution structures from even the tiniest of crystals, less than a few hundred nanometers thick. MicroED complements frontier advances in crystallography and represents part of the rebirth of cryo-EM that is making macromolecular structure determination more accessible for all. Here we review the concept and practice of MicroED, for both the electron microscopist and crystallographer. Where other reviews have addressed specific details of the technique (Hattne et al., 2015; Shi et al., 2016; Shi, Nannenga, Iadanza, & Gonen, 2013), we aim to provide context and highlight important features that should be considered when performing a MicroED experiment. PMID:27572734

  4. The influence of sonority on the production of words ending in -ed by Brazilian EFL learners

    Directory of Open Access Journals (Sweden)

    Fernanda Delatorre

    2010-11-01

    Full Text Available This study investigated the influence of sonority on the production of vowel epenthesis in verbs ending in -ed by Brazilian learners of English. Participants were twenty-six upper-intermediate Brazilian EFL learners who read and audio-recorded ten paragraphs containing 91 verbs ending in ed. The results demonstrated that sonority influenced mispronunciations since the least sonorous obstruents preceding -ed induced more vowel epenthesis than the more sonorous sonorants, which in turn induced more epenthesis than vowels in the same position. The results also demonstrated that within the class of obstruents, affricates preceding -ed induced more epenthesis than stops, which induced more epenthesis than fricatives, and that, within the class of sonorants, nasals induced more epenthesis than liquids. These results suggest that markedness in terms of sonority affects the production of vowel epenthesis in words ending in -ed.

  5. The influence of sonority on the production of words ending in -ed by Brazilian EFL learners

    Directory of Open Access Journals (Sweden)

    Fernanda Delatorre

    2008-01-01

    Full Text Available http://dx.doi.org/10.5007/2175-8026.2008n55p83 This study investigated the influence of sonority on the production of vowel epenthesis in verbs ending in -ed by Brazilian learners of English. Participants were twenty-six upper-intermediate Brazilian EFL learners who read and audio-recorded ten paragraphs containing 91 verbs ending in ed. The results demonstrated that sonority influenced mispronunciations since the least sonorous obstruents preceding -ed induced more vowel epenthesis than the more sonorous sonorants, which in turn induced more epenthesis than vowels in the same position. The results also demonstrated that within the class of obstruents, affricates preceding -ed induced more epenthesis than stops, which induced more epenthesis than fricatives, and that, within the class of sonorants, nasals induced more epenthesis than liquids. These results suggest that markedness in terms of sonority affects the production of vowel epenthesis in words ending in -ed.

  6. Steel Energy and Environmental Profile

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2000-08-01

    Major steelmaking processes (from ironmaking through fabrication and forming) and their associated energy requirements have been profiled in this 2001 report (PDF 582 KB). This profile by Energetics, Inc. also describes the waste streams generated by each process and estimates annual emissions of CO2 and criteria pollutants.

  7. Contributor Form

    Directory of Open Access Journals (Sweden)

    Chief Editor

    2014-09-01

    to produce preprints or reprints and translate into languages other than English for sale or free distribution; and 4 the right to republish the work in a collection of articles in any other mechanical or electronic format. We give the rights to the corresponding author to make necessary changes as per the request of the journal, do the rest of the correspondence on our behalf and he/she will act as the guarantor for the manuscript on our behalf. All persons who have made substantial contributions to the work reported in the manuscript, but who are not contributors, are named in the Acknowledgment and have given me/us their written permission to be named. If I/we do not include an Acknowledgment that means I/we have not received substantial contributions from non-contributors and no contributor has been omitted.S NoAuthors' NamesContribution (IJCME Guidelines{1 substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data; 2 drafting the article or revising it critically for important intellectual content; and 3 final approval of the version to be published. Authors should meet conditions 1, 2, and 3}.SignatureDate                              Note: All the authors are required to sign independently in this form in the sequence given above. In case an author has left the institution/country and whose whereabouts are not known, the senior author may sign on his/her behalf taking the responsibility.No addition/deletion/ or any change in the sequence of the authorship will be permissible at a later stage, without valid reasons and permission of the Editor.If the authorship is contested at any stage, the article will be either returned or will not be processed for publication till the issue is solved.Maximum up to 4 authors for short communication and up to 6 authors for original article.

  8. Contributors Form

    Directory of Open Access Journals (Sweden)

    Chief Editor

    2016-06-01

    to produce preprints or reprints and translate into languages other than English for sale or free distribution; and 4 the right to republish the work in a collection of articles in any other mechanical or electronic format. We give the rights to the corresponding author to make necessary changes as per the request of the journal, do the rest of the correspondence on our behalf and he/she will act as the guarantor for the manuscript on our behalf. All persons who have made substantial contributions to the work reported in the manuscript, but who are not contributors, are named in the Acknowledgment and have given me/us their written permission to be named. If I/we do not include an Acknowledgment that means I/we have not received substantial contributions from non-contributors and no contributor has been omitted.S NoAuthors' NamesContribution (IJCME Guidelines{1 substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data; 2 drafting the article or revising it critically for important intellectual content; and 3 final approval of the version to be published. Authors should meet conditions 1, 2, and 3}.SignatureDate                              Note: All the authors are required to sign independently in this form in the sequence given above. In case an author has left the institution/country and whose whereabouts are not known, the senior author may sign on his/her behalf taking the responsibility.No addition/deletion/ or any change in the sequence of the authorship will be permissible at a later stage, without valid reasons and permission of the Editor.If the authorship is contested at any stage, the article will be either returned or will not be processed for publication till the issue is solved.Maximum up to 4 authors for short communication and up to 6 authors for original article.

  9. Recession, Retrenchment, and Recovery: State Higher Education Funding & Student Financial Aid. Volume II: State Profiles

    Science.gov (United States)

    Ambrose, Allison S.; Hines, Edward R.; Hodel, Ross A.; Kelly, Kathleen F.; Mushrush, Christopher E., Pruden, Sheila J.; Vogt, W. Paul

    2006-01-01

    This report is a companion to "Recession, Retrenchment and Recovery: Higher Education Funding and Student Financial Aid" (ED502180). It provides profiles of individual states and their performance on a variety of measures used in the economic and fiscal analysis of the Recession, Retrenchment and Recovery project. The profiles describe the results…

  10. SEM and EDS Characterisation of Layering TiOx Growth onto the Cutting Tool Surface in Hard Drilling Processes of Ti-Al-V Alloys

    Directory of Open Access Journals (Sweden)

    M. Álvarez

    2011-01-01

    Full Text Available Scanning electron microscopy (SEM has been used to identify and analyse the secondary adhesion effect precursors formed during the dry drilling processes of Ti-6Al-4V alloy over the rake face and flute of the drilling tools. Subsequent analysis with energy dispersive spectroscopy (EDS was enabled to distinguish its compositional characteristics. Thus, according to the EDS obtained data, a stratified multi built-up layer (MBUL composed by TiOx is formed over the rake face of the tool. Furthermore, this multi-layer adhered allows initially the built-up edge (BUE development close to the edge of the tool by a mechanical adhesion mechanism. In a second step, it is responsible for the formation of a thicker secondary BUL which avoids the chip flow, and it provokes the tool collapse. These mechanisms are different from those observed in the dry machining of other alloys such as steels, nickel-based alloys, or aluminium alloys.

  11. Biophysical Profile

    Science.gov (United States)

    ... and pregnancy High-risk pregnancy Biophysical profile About Advertisement Mayo Clinic does not endorse companies or products. ... a Job Site Map About This Site Twitter Facebook Google YouTube Pinterest Mayo Clinic is a not- ...

  12. Does a Structured Data Collection Form Improve The Accuracy of ...

    African Journals Online (AJOL)

    Objectives: To determine the extent to which use of a structured data collection form (SDCF) affected the diagnostic accuracy of AAP. Methodology: A before and after study carried out from October 2011 to March 2012 of patients aged 13 years and older presenting with AAP in the emergency department (ED) of Aga Khan ...

  13. Profiling cancer

    DEFF Research Database (Denmark)

    Ciro, Marco; Bracken, Adrian P; Helin, Kristian

    2003-01-01

    In the past couple of years, several very exciting studies have demonstrated the enormous power of gene-expression profiling for cancer classification and prediction of patient survival. In addition to promising a more accurate classification of cancer and therefore better treatment of patients......, gene-expression profiling can result in the identification of novel potential targets for cancer therapy and a better understanding of the molecular mechanisms leading to cancer....

  14. Tecniche, forme costruttive ed evoluzione nei nuraghi del Sarcidano. Studio su un campione di fortezze di Nurri e Orroli

    OpenAIRE

    Angela Orgiana

    2012-01-01

    Un’indagine approfondita su un campione di fortezze del Sarcidano offre uno spunto di riflessione sulle caratteristiche ar­chitettoniche dei nuraghi, che porta a distinguere le tecniche impiegate in tutto il territorio isolano da quelle proprie della tradizione locale. L’individuazione di moduli architettonici costanti conduce a ipotizzare la presenza di maestranze specializzate che, utilizzando le già accertate unità di misura comuni, fornivano la loro manodopera in un territorio piuttosto a...

  15. Omofobia ed eterosessismo nei contesti educativi. Le forme, le specificità e le strategie di intervento

    OpenAIRE

    Gabriele Prati; Luca Pietrantoni; Elisa Saccinto

    2011-01-01

    In adolescent environments there are frequent occurrences of aggressive verbal and physical behaviour regarding homosexuality. In these situations young boys are motivated by a series of complex contributory factors such as difficulty in finding significant adults who are prepared to discuss sexuality; the growth and role of gender; group dynamics – how the perception that power over others is something that guarantees success and immediate social integration; the cultural and social dimensio...

  16. Microstructural characterization of autogenous laser welds on 316L stainless steel using EBSD and EDS.

    Science.gov (United States)

    Kell, J; Tyrer, J R; Higginson, R L; Thomson, R C

    2005-02-01

    This research is concerned with autogenous welding of 316L stainless steel and the microstructure generated by such a process. Autogenous welding does not require a filler material and in this case relies on an initial shallow melt phase to maintain a conduction limited weld. Essentially, a high power laser beam traverses the substrate, with the beam shaped by conventional optics, which produces a Gaussian irradiance distribution; or with a diffractive optical element, used to produce a uniform irradiance distribution. Initial results have shown that due to the nature of the heating cycle, complex microstructures are developed. These fine, complicated microstructures cannot be satisfactorily resolved and quantified using standard optical microscopy techniques. Electron backscatter diffraction (EBSD) and energy dispersive spectroscopy (EDS) have been carried out on a number of different microstructures prepared using a range of welding parameters. It is demonstrated that the simultaneous determination of the chemistry and crystallography is a very useful tool for rapid identification of the different phases formed on solidification as a consequence of varying welding procedures.

  17. AB006. Erectile dysfunction (ED) as a marker for cardiovascular diseases (CVD)

    Science.gov (United States)

    Torres, Luiz Otavio

    2015-01-01

    In 1973 V. Michal, a vascular surgeon said “Erectile dysfunction (ED) is related to diseases of the vascular bed”. And this makes sense since ED and cardiovascular diseases (CVD) share many risk factors like aging, obesity, inactivity, smoking, depression, dyslipidemia, hypertension, diabetes/insuline resistance. These conditions may lead to an oxidative stress which ultimately can promote vasoconstriction, thrombosis, atherosclerosis and finally ED and CVD. One of the most accepted Idea is that small vessels plug earlier, it means, small arteries when have for example 50% of obstruction will probably have a clinical manifestation before bigger arteries!

  18. [Efficacy of low-dose tadalafil on ED assessed by Self-Esteem and Relationship Questionnaire].

    Science.gov (United States)

    Li, Jing-Ping; Li, Fei; Guo, Wen-Bin; Zhou, Qi-Zhao; Liu, Cun-Dong; Mao, Xiang-Ming; Tan, Wan-Long; Zheng, Shao-Bin

    2010-12-01

    To explore the effects of low-dose oral tadalafil on self-esteem, confidence and sexual relationship in ED patients. We treated 17 ED patients with oral tadalafil at the low dose of 5 mg once daily for 12 weeks, and used the paired t test to compare their scores on The Self-Esteem and Relationship Questionnaire (SEAR) and IIEF-5 and the results of nocturnal penile tumescence (NPT) obtained by nocturnal electrobioimpedance volumetric assessment (NEVA) before and after the medication. The scores on SEAR and IIEF-5 were significantly increased (P self-esteem, confidence, sexual relationship satisfaction and NPT of ED patients.

  19. Irene V. Jackson, (ed.) More Than Dancing: Essays on Afro ...

    African Journals Online (AJOL)

    parade, the college football match and its associated or fully integrated art forms, such as drum majorettes, and display marching get given their full, if unelaborated, due in McGinty's research. Finally however, it seems a shame that after having made this point she does not mention the fact that Afro-Americans still do figure ...

  20. In vitro steroid profiling system for the evaluation of endocrine disruptors.

    Science.gov (United States)

    Nakano, Yosuke; Yamashita, Toshiyuki; Okuno, Masashi; Fukusaki, Eiichiro; Bamba, Takeshi

    2016-09-01

    Endocrine disruptors (ED) are chemicals that affect various aspects of the endocrine system, often leading to the inhibition of steroidogenesis. Current chemical safety policies that restrict human exposure to such chemicals describe often time-consuming and costly methods for the evaluation of ED effects. We aimed to develop an effective tool for accurate phenotypic chemical toxicology studies. We developed an in vitro ED evaluation system using gas chromatography/mass spectrometry (GC/MS/MS) methods for metabolomic analysis of multi-marker profiles. Accounting for sample preparation and GC/MS/MS conditions, we established a screening method that allowed the simultaneous analysis of 17 steroids with good reproducibility and a linear calibration curve. Moreover, we applied the developed system to H295R human adrenocortical cells exposed to forskolin and prochloraz in accordance with the Organization for Economic Cooperation and Development (OECD) guidelines and observed dose-dependent variations in steroid profiles. While the OECD guidelines include only testosterone and 17β-estradiol, our system enabled a comprehensive and highly sensitive analysis of steroid profile alteration due to ED exposure. The application of our ED evaluation screen could be economical and provide novel insights into the hazards of ED exposure to the endocrine system. Copyright © 2016 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

  1. Review: Funston, John (ed. (2009, Divided Over Thaksin: Thailand’s Coup and Problematic Transition

    Directory of Open Access Journals (Sweden)

    Paul Chambers

    2010-04-01

    Full Text Available Review of the edited volume: Funston, John (ed. (2009, Divided Over Thaksin: Thailand’s Coup and Problematic Transition, Chiangmai: Silkworm Books, Singapore: ISEAS. ISBN 978-981-230-961-7, 203 pages.

  2. Patient-Centered Care Transition for Patients Admitted through the ED: Improving Patient and Employee Experience

    National Research Council Canada - National Science Library

    Algauer, Andrea; Rivera, Stephanie; Faurote, Robert

    2015-01-01

    With increasing wait times in emergency departments (ED) across America, there is a need to streamline the inpatient admission process in order to decrease wait times and more important, to increase patient and employee satisfaction...

  3. Hispaania võib oma väed Iraagist ära tuua / Erkki Bahovski

    Index Scriptorium Estoniae

    Bahovski, Erkki, 1970-

    2004-01-01

    Hispaania parlamendivalimised võitnud sotsialistliku partei liider, arvatav uus peaminister Jose Luis Rodriguez Zapatero lubas Hispaania väed Iraagist ära tuua. Diagrammid: Hispaania valimistulemused

  4. Jean Libis, Fabio Ferreira, Catherine Gublin, Sarah Mezaguer (eds., Les Lectures de Gaston Bachelard. Index bibliographique

    Directory of Open Access Journals (Sweden)

    Aurosa Alison

    2012-10-01

    Full Text Available Jean Libis, Fabio Ferreira, Catherine Gublin, Sarah Mezaguer (eds., Les Lectures de Gaston Bachelard. Index bibliographique (Paris, Presse Universitaire de Franche-Comté, 2011 ISBN: 978-2-84867-392 di     Aurosa Alison

  5. G. L. Castelli, principe di Torremuzza, numismatico ed antichista ad Halaesa Archonidea

    National Research Council Canada - National Science Library

    Antonino Crisà

    2009-01-01

    ... dell’antiquaria siciliana del XVIII secolo. Questo contributo esamina l’attività di ricerca di Castelli, interessato alla monetazione ed alle evidenze archeologiche di Halaesa Archonidea, oggi identificata nei pressi di Tusa (ME). È proposta...

  6. In a dynamic health care environment, take steps to fully leverage case managers in the ED.

    Science.gov (United States)

    2013-09-01

    In an effort to create more capacity while also improving the patient experience, the University of Virginia Medical Center (UVAMC) in Charlottesville, VA, has taken steps to better leverage case managers in the ED. Under the new approach, case managers work alongside clinicians on the floor. They step in when added resources are needed or services need to be arranged before discharge. Administrators say the new ED case manager role has helped UVAMC reduce medically unnecessary length-of-stay by 34 minutes, enabling the hospital to see up to 4,000 additional patients per year. The ED-based case managers learn of patients who may benefit from their involvement by regularly participating in flow rounds with clinicians on the floor. Administrators are eyeing future improvements from the approach, including a concentrated effort to reduce visits to the ED by frequent utilizers.

  7. Drying Time and Quality of EDS-Treated Compared to Untreated Beech Wood (Fagus japonica

    Directory of Open Access Journals (Sweden)

    Mihaela CAMPEAN

    2017-09-01

    Full Text Available The paper presents the results of an experimental study performed with Japanese beech timber heattreated by the EDS method (Japanese patent and then dried in order to evaluate the effects of this treatment upon the drying rate and the drying uniformity. The obtained results demonstrate benefitting effects of the EDS treatment both upon the drying time and the drying quality. The drying rate of EDS-treated beech wood is by 29% higher in the case of wood without red heart and by 11% higher in the case of wood with red heart. As far as the drying uniformity is concerned, the minimum moisture content gradient across the 50mm thickness of the timber boards was recorded for the EDS-treated beech wood with red heart (∆MC=1.66, by 21.7% lower than in the case of untreated beech wood with red heart.

  8. Physical distribution of Ni, Pb and Zn in reclaimed mine soils observed by FE-SEM with an EDS detector.

    Science.gov (United States)

    Asensio, V; Covelo, E F

    2015-09-01

    The aim of this study was to physically demonstrate the associations between Ni, Pb and Zn and the different soil components. To achieve this, several soil samples were observed by field emission-scanning electron microscope (FE-SEM) equipped with an energy dispersive spectrometer (EDS) detector. The samples came from mine sites vegetated and/or amended with wastes (sewage sludges and paper mill residues). The concentrations of metals in the different soil fractions were quantified by a chemical sequential extraction in a previous study. The sorption capacity of the soils was evaluated with sorption experiments using the batch method. We corroborated the results obtained by the sequential extraction of metals as well as the sorption experiments with the observations from the FE-SEM with the EDS. We physically observed the associations between Ni, Pb and Zn and oxides, organic matter and clays. We also observed PbCaCO3 crystals in one of the soils, presumably formed during the sorption experiment. As it is not possible to know with complete certainty how Pb was retained by calcium in this soil by only using chemical methods, the use of microscopic techniques is crucial to ascertain how metals are associated with the different soil fractions.

  9. 2003 annual results of EdF group; Resultats annuels 2003 du groupe EDF

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-03-01

    The Electricite de France (EdF) group Board of Directors, meeting on March 11, 2004, under the Chairmanship of Francois Roussely, reviewed the audited consolidated financial statements for the year ended 12/31/2003. This document presents the consolidated results of EdF group for 2003: consolidated financial statements, highlights of the year, focus on 2003 events, commercial results, EDF in Europe and worldwide, EDF France highlights, key figures. (J.S.)

  10. Bedside point of care toxicology screens in the ED: Utility and pitfalls

    OpenAIRE

    Bhalla, Ashish

    2014-01-01

    Exposure to drugs and toxins is a major cause for patients’ visits to the emergency department (ED). For most drugs-of-abuse intoxication, ED physicians are skeptical to rely on results of urine drug testing for emergent management decisions. This is partially because immunoassays, although rapid, have limitations in sensitivity and specificity and chromatographic assays, which are more definitive, are more labor intensive. Testing for toxic alcohols is needed, but rapid commercial assays are...

  11. Test Review: Gilliam, J. E. (2015), "Attention-Deficit/Hyperactivity Disorder Test" (2nd Ed) [Assessment Instrument]. Austin, TX: Pro-Ed.

    Science.gov (United States)

    Perdue, Elizabeth A.

    2016-01-01

    The "Attention-Deficit/Hyperactivity Disorder Test-Second Edition" (ADHDT-2) is published through Pro-Ed in Austin, Texas. It was formally published in 2014, following critical revisions of the ADHDT, the reportedly popular initial version of this test that was published in 1995. The ADHDT-2 purports to act as a screener for individuals…

  12. EdF-Gaz de France. No merger without dismembering; EdF-Gaz de France. Pas de fusion sans depecage

    Energy Technology Data Exchange (ETDEWEB)

    Lepetit, V

    2007-03-15

    Gathering together the two historical French energy monopolies, Electricite de France (EdF) and Gaz de France (GdF), and warranting low electricity and gas prices is still an attractive idea for some political and syndicate representatives. However, such a merger would create a dominating position which is forbidden with respect to Brussels criteria. (J.S.)

  13. Densified waste form and method for forming

    Science.gov (United States)

    Garino, Terry J.; Nenoff, Tina M.; Sava Gallis, Dorina Florentina

    2015-08-25

    Materials and methods of making densified waste forms for temperature sensitive waste material, such as nuclear waste, formed with low temperature processing using metallic powder that forms the matrix that encapsulates the temperature sensitive waste material. The densified waste form includes a temperature sensitive waste material in a physically densified matrix, the matrix is a compacted metallic powder. The method for forming the densified waste form includes mixing a metallic powder and a temperature sensitive waste material to form a waste form precursor. The waste form precursor is compacted with sufficient pressure to densify the waste precursor and encapsulate the temperature sensitive waste material in a physically densified matrix.

  14. Chemical profiles along olivine crystallographic axes: a record of the melt-rock interaction sequence forming Hole U1309D Olivine-rich troctolites (Atlantis Massif, MAR, 30°N)

    Science.gov (United States)

    Ferrando, Carlotta; Godard, Marguerite; Ildefonse, Benoit; Rampone, Elisabetta

    2017-04-01

    phases. Dunitic and troctolitic domains display different microstructural and geochemical signatures. Their mineral modal percentages and compositions are not correlated along typical trends of fractional crystallization. The dunitic domain has olivines showing lower Mg# (82-83, against 85-86 in troctolitic domain), higher Ni and Mn contents. In the dunitic domain olivine, plagioclase and clinopyroxene are more enriched in trace elements compared to those in the troctolitic domain. These compositions reveal reaction and re-equilibration processes of pre-existing mantle-derived olivine-rich rock with an infiltrating olivine-undersaturated MORB-type melt. Chemical traverses along principal crystallographic axes of olivine reveal flat cpxcore-cpxrim-olrim-olcore profiles for all major and trace elements with the exception of Ca and Y, which are modified due to late subsolidus re-equilibration. Flat profiles indicate either (i) slow olivine dissolution kinetics relative to equilibration of primary olivine with incoming melts or (ii) preservation of initial chemical signature and fast olivine dissolution kinetics. These two end-member scenarii are investigated using thermodynamic models to better constrain (dis-)equilibrium relationships between mineral phases and reactive percolation modeling to determine the contribution of advective and diffusive processes to local chemical signatures. Drouin, M., Godard, M., Ildefonse, B., Bruguier, O., Garrido, C.J. (2009): Geochemical and petrographic evidence for magmatic impregnation in the oceanic lithosphere at Atlantis Massif, Mid-Atlantic Ridge (IODP Hole U1309D, 30°N). Chem Geol 264, 71-88. Drouin, M., Ildefonse, B., Godard, M. (2010) A microstructural imprint of melt impregnation in slow-spread lithosphere: olivine-rich troctolites from the Atlantis Massif (Mid-Atlantic Ridge 30°N, IODP Hole U1309D). Geochem Geophys Geosyst 11:Q06003, doi:10.1029/2009GC002995. Godard, M., et al. (2009): Geochemistry of a long in-situ section

  15. Impact of revised triage to improve throughput in an ED with limited traditional fast track population.

    Science.gov (United States)

    Gardner, Ryan M; Friedman, Nathan A; Carlson, Michael; Bradham, Tamala S; Barrett, Tyler W

    2018-01-01

    Emergency department (ED) crowding is associated with patient safety concerns, increased patients left without being seen (LWBS), low patient satisfaction, and lost ED revenue. The objective was to measure the impact of a revised triage process on ED throughput. This study took place at an urban, university-affiliated, adult ED with an annual census of 70,000 and admission rate of 34%. The revised triage approach included: identifying eligible patients at triage based on complaint, comorbidities, and illness acuity; and reallocating a nurse practitioner (NP) into our triage area. We trialed the intervention from 1100-2300 on weekdays from January 13-26, 2016. Adult patients who were not likely to require intensive evaluations were eligible. Primary outcomes were throughput measures including: time to provider, ED length of stay (LOS), and LWBS. Pre- and post-intervention metrics were compared using the Mann-Whitney U test, given the non-normal distribution of the metrics. The NP evaluated 120 patients of which 101 (84%) were discharged, 3 (2.5%) admitted, and 16 (13%) required more intense evaluation. Time to provider decreased from a median (IQR) of 42 (16, 114) to 27 (12.4, 81.5) minutes (ptriage intervention was associated with improvements in several ED throughput metrics and a reduction in LWBS. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. Registered nurse scope of practice and ED complaint-specific protocols.

    Science.gov (United States)

    Castner, Jessica; Grinslade, Susan; Guay, Jennifer; Hettinger, A Zach; Seo, Jin Young; Boris, Lenore

    2013-09-01

    The use of complaint-specific protocols (CSPs) by emergency registered nurses (RNs) can improve ED efficiency. However, RN practice is influenced by regulatory environments that may facilitate or inhibit the use of protocols. The purpose of this policy analysis was to explore the language of state boards of nursing scope-of-practice documents related to the use of RN-initiated CSPs in the ED setting. A qualitative descriptive design was used to investigate how the RN's scope of practice relates to the use of CSPs in ED settings across states. Data were collected from state boards of nursing Web site documents. Three major themes emerged: cautiously within scope, intentionally vague/silent, and outside scope. Seven states (Connecticut, Illinois, Kansas, Louisiana, New Jersey, New York, and Oklahoma) were identified where RN-initiated CSPs appear to be currently outside the RN's scope of practice. Therefore 18% of the US population, or 55,973,900 people, resides in states where CSPs are not allowed. State-to-state inconsistencies in the RN's scope of practice may interfere with the implementation of practices that enhance ED efficiency. RNs in all states must ensure that they have the requisite knowledge, skill, and documented competency to implement CSPs, if supported by their employing facility. Efforts to standardize ED RN education and policy are warranted. Continued research is needed assess the impact of RN-initiated CSPs on the efficiency of ED care. Copyright © 2013 Emergency Nurses Association. Published by Mosby, Inc. All rights reserved.

  17. Chemical analysis and biological testing of materials from the EDS coal liquefaction process: a status report

    Energy Technology Data Exchange (ETDEWEB)

    Later, D.W.; Pelroy, R.A.; Wilson, B.W.

    1984-05-01

    Representative process materials were obtained from the EDS pilot plant for chemical and biological analyses. These materials were characterized for biological activity and chemical composition using a microbial mutagenicity assay and chromatographic and mass spectrometric analytical techniques. The two highest boiling distillation cuts, as well as process solvent (PS) obtained from the bottoms recycle mode operation, were tested for initiation of mouse skin tumorigenicity. All three materials were active; the crude 800/sup 0 +/F cut was substantially more potent than the crude bottoms recycle PS or 750 to 800/sup 0/F distillate cut. Results from chemical analyses showed the EDS materials, in general, to be more highly alkylated and have higher hydroaromatic content than analogous SRC II process materials (no in-line process hydrogenation) used for comparison. In the microbial mutagenicity assays the N-PAC fractions showed greater activity than did the aliphatic hydrocarbon, hydroxy-PAH, or PAH fractions, although mutagenicity was detected in certain PAH fractions by a modified version of the standard microbial mutagenicity assay. Mutagenic activities for the EDS materials were lower, overall, than those for the corresponding materials from the SRC II process. The EDS materials produced under different operational modes had distinguishable differences in both their chemical constituency and biological activity. The primary differences between the EDS materials studied here and their SRC II counterparts used for comparison are most likely attributable to the incorporation of catalytic hydrogenation in the EDS process. 27 references, 28 figures, 27 tables.

  18. Effect of Job Specialization on the Hospital Stay and Job Satisfaction of ED Nurses.

    Science.gov (United States)

    Shamsi, Vahid; Mahmoudi, Hosein; Sirati Nir, Masoud; Babatabar Darzi, Hosein

    2016-02-01

    In recent decades, the increasing crowdedness of the emergency departments has posed various problems for patients and healthcare systems worldwide. These problems include prolonged hospital stay, patient dissatisfaction and nurse burnout or job dissatisfaction. The aim of this study was to investigate the effect of emergency department (ED) nurses' job specialization on their job satisfaction and the length of patient stay in the ED. This before-after quasi-experimental study was conducted from April to May 2014 at the Baqiyatallah Hospital, Tehran, Iran. Initially, 35 patients were recruited as controls and the length of their stay in the ED was measured in minutes via a chronometer; Moreover, nurses' job satisfaction was evaluated using the Mohrman-Cooke-Mohrman job satisfaction scale. Then, a job specialization intervention was developed based on the stabilization model. After that, 35 new patients were recruited to the treatment group and received specialized care services. Accordingly, the length of their stay in the ED was measured. Moreover, the same nurses' job satisfaction was re-evaluated after the study. The study intervention lasted one month. Data were analyzed using the SPSS software version 20 and statistical tests such as the Kolmogrov-Smirnov, the paired and the independent t, and chi-square tests. There was a significant difference between the two groups of patients concerning the length of their stay in the ED (P nurses had greater job satisfaction after the study (P nurses' satisfaction and relieve the crowdedness of the EDs.

  19. The use of SEM/EDS method in mineralogical analysis of ordinary chondritic meteorite

    Directory of Open Access Journals (Sweden)

    Breda Mirtič

    2009-12-01

    Full Text Available The aim of this study was to evaluate the potential of scanning electron microscopy coupled with energy dispersiveX-ray spectroscopy (SEM/EDS for determination of mineral phases according to their stoichiometry and assessment of mineral composition of ordinary chondritic meteorite. For the purposes of this study, H3 type ordinary chondritic meteorite Abbott was selected. SEM/EDS allows identification and characterisation of mineralphases, whose size is below the resolution of an optical microscope. Mineral phases in chondrules and interstitial matrix were located in backscattered electron (BSE mode and were assessed from atomic proportions of constituent elements, obtained by the EDS analysis. SEM/EDS analyses of mineral phases showed that Abbott meteorite is characterised by Fe-rich (Fe, Ni-alloy kamacite, Fe-sulphide troilite or pyrrhotite, chromite, Mg-rich olivine, orthopyroxene bronzite or hypersthene, clinopyroxene Al-diopside, acid plagioclase oligoclase, accessory mineral chlorapatite and secondary minerals Fe-hydroxides (goethite or lepidocrocite. Results of semi-quantitative analyses confirmed that most of analysed mineralphases conform well to stoichiometric minerals with minor deviations of oxygen from stoichiometric proportions. Comparison between mineral phases in chondrules and interstitial matrix was also performed, however it showed no significant differences in elemental composition.Differences in chemical composition between minerals in interstitial matrix and chondrules are sometimes too small to be discernedby the SEM/EDS, therefore knowledge of SEM/EDS capabilities is important for correct interpretation of chondrite formation.

  20. [Survey on the barriers in providing the mental health services to the suicide attempters in ED].

    Science.gov (United States)

    Zhao, Xiaohui; Li, Tao; Hong, Xia; Jiang, Yinan; Xiong, Nana; Cao, Jinya; Wei, Jing

    2015-06-16

    The purpose of this study was to explore the barriers existing in medical settings behind the phenomenon that few suicide attempters were provided by mental health services when they got treatment in the general hospital ED. An anonymous and voluntary survey was administered among two groups: ED physicians and psychiatrists. Two tertiary general hospitals and one psychiatric hospital were chosen through convenience sampling. Suicide Behavior Attitude Questionnaire and a self-made questionnaire to evaluate barriers were used. The response rate was 68.7% for ED physicians, and 87.0% for psychiatrists. ED physicians generally scored unfavorably than psychiatrists on many items in SBAQ (P suicide attempters should have access to mental health services, the median of the scores = 10 for both group (P = 0.059), meaning highly agree. Some consistent barriers could be summarized from the self-made questionnaire. The majority of ED physicians in general hospitals still hold some misunderstanding about the suicide attempters, but they fully agree that the suicide attempters should have access to mental health services. The barriers for psychiatrists are clear.The barriers for ED physicians are complicated but workable.

  1. Fellow Profile

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1971 Section: Chemistry. Narasimhan, Prof. Palliakaranai Thirumalai Ph.D. (Madras), FNA, FNASc. Date of birth: 28 July 1928. Date of death: 3 May 2013. Specialization: Theoretical Chemistry and Magnetic Resonance Last known address: 1013, Lupine Drive, Sunnyvale, CA 94086, USA. YouTube ...

  2. Extensive FE-SEM/EDS, HR-TEM/EDS and ToF-SIMS studies of micron- to nano-particles in anthracite fly ash.

    Science.gov (United States)

    Ribeiro, Joana; DaBoit, Kátia; Flores, Deolinda; Kronbauer, Marcio A; Silva, Luis F O

    2013-05-01

    The generation of anthropogenic carbonaceous matter and mixed crystalline/amorphous mineral ultrafine/nano-particles in the 1 to 100 nm size range by worldwide coal power plants represents serious environmental problems due to their potential hazards. Coal fly ash (CFA) that resulted from anthracite combustion in a Portuguese thermal power plant was studied in this work. The physico-chemical characterization of ultrafine/nano-particles present in the CFA samples and their interaction with environment are the aim of this study. The methodologies applied for this work were field emission scanning electron microscopy (FE-SEM) with energy dispersive X-ray spectroscopy (EDS), high-resolution transmission electron microscopy with energy dispersive X-ray spectroscopy (HR-TEM/EDS) and time of flight secondary ion mass spectrometry (ToF-SIMS). Some hazardous volatile elements, C, N, S and Hg contents were also determined in the studied samples. Generally, the CFA samples comprise carbonaceous, glassy and metallic solid spheres with some containing mixed amorphous/crystalline phases. The EDS analysis coupled with the FE-SEM and HR-TEM observations of the fly ash particles with 100 to 0.1 nm demonstrates that these materials contain a small but significant proportion of encapsulated HVEs. In addition, the presence of abundant multi-walled carbon nanotubes (MWCNTs) and amorphous carbon particles, both containing hazardous volatile elements (HVEs), was also evidenced by the FE-SEM/EDS and HR-TEM/EDS analysis. A wide range of organic and inorganic compounds was determined by chemical maps obtained in ToF-SIMS analysis. Copyright © 2013 Elsevier B.V. All rights reserved.

  3. Extensive FE-SEM/EDS, HR-TEM/EDS and ToF-SIMS studies of micron- to nano-particles in anthracite fly ash

    Energy Technology Data Exchange (ETDEWEB)

    Ribeiro, Joana [Centro de Geologia, Universidade do Porto, Rua do Campo Alegre, 687, 4169-007 Porto (Portugal); DaBoit, Kátia [Institute of Environmental Research and Human Development, IPADHC, Capivari de Baixo, Santa Catarina (Brazil); Flores, Deolinda [Centro de Geologia, Universidade do Porto, Rua do Campo Alegre, 687, 4169-007 Porto (Portugal); Departamento de Geociências, Ambiente e Ordenamento do Território, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre, 687, 4169-007 Porto (Portugal); Kronbauer, Marcio A. [Laboratory of Environmental Researches and Nanotechnology Development, Centro Universitário La Salle, Victor Barreto, 2288 Centro 92010-000, Canoas, RS (Brazil); Silva, Luis F.O., E-mail: felipeqma@hotmail.com [Laboratory of Environmental Researches and Nanotechnology Development, Centro Universitário La Salle, Victor Barreto, 2288 Centro 92010-000, Canoas, RS (Brazil); Environmental Science and Nanotechnology Department, Catarinense Institute of Environmental Research and Human Development, IPADHC, Capivari de Baixo, Santa Catarina (Brazil)

    2013-05-01

    The generation of anthropogenic carbonaceous matter and mixed crystalline/amorphous mineral ultrafine/nano-particles in the 1 to 100 nm size range by worldwide coal power plants represents serious environmental problems due to their potential hazards. Coal fly ash (CFA) that resulted from anthracite combustion in a Portuguese thermal power plant was studied in this work. The physico-chemical characterization of ultrafine/nano-particles present in the CFA samples and their interaction with environment are the aim of this study. The methodologies applied for this work were field emission scanning electron microscopy (FE-SEM) with energy dispersive X-ray spectroscopy (EDS), high-resolution transmission electron microscopy with energy dispersive X-ray spectroscopy (HR-TEM/EDS) and time of flight secondary ion mass spectrometry (ToF-SIMS). Some hazardous volatile elements, C, N, S and Hg contents were also determined in the studied samples. Generally, the CFA samples comprise carbonaceous, glassy and metallic solid spheres with some containing mixed amorphous/crystalline phases. The EDS analysis coupled with the FE-SEM and HR-TEM observations of the fly ash particles with 100 to 0.1 nm demonstrates that these materials contain a small but significant proportion of encapsulated HVEs. In addition, the presence of abundant multi-walled carbon nanotubes (MWCNTs) and amorphous carbon particles, both containing hazardous volatile elements (HVEs), was also evidenced by the FE-SEM/EDS and HR-TEM/EDS analysis. A wide range of organic and inorganic compounds was determined by chemical maps obtained in ToF-SIMS analysis. - Highlights: ► We examine changes in the level of ultrafine and nanoparticles of coal mining. ► Increasing geochemical information will increase human health information in this area. ► Electron bean and Tof-SIMS increase area information.

  4. Shannon Cain, ed., Roadside Curiosities. Stories about American Pop Culture

    OpenAIRE

    Labarre, Nicolas

    2015-01-01

    Roadside Curiosities is a collection of contemporary short stories which promises to marry “highbrow” and “lowbrow,” “literary fiction to American popular culture” (back cover). This union takes the form of twenty short stories selected by Shannon Cain, herself a short-story writer as well as a creative writing teacher, featuring Madonna, a superhero, the spectral image of Cary Grant, the hero of the Donkey Kong video game and more. In her introduction to the collection, Cain surprisingly re...

  5. CRC standard probability and statistics tables and formulae Student ed.

    CERN Document Server

    Kokoska, Stephen

    2000-01-01

    Users of statistics in their professional lives and statistics students will welcome this concise, easy-to-use reference for basic statistics and probability. It contains all of the standardized statistical tables and formulas typically needed plus material on basic statistics topics, such as probability theory and distributions, regression, analysis of variance, nonparametric statistics, and statistical quality control.For each type of distribution the authors supply:?definitions?tables?relationships with other distributions, including limiting forms?statistical parameters, such as variance a

  6. Nursing intervention for geriatric patients dischargedhome from ED

    DEFF Research Database (Denmark)

    Rosted, Elizabeth Emilie

    2009-01-01

    , har forebyggende effekt. Formål Formålet er at undersøge effekten af: 1. at identificere geriatriske patienter (>70år) i risiko for fald i funktionsevne, genindlæggelse, flytning til plejehjem og død 2. den sygeplejefaglige intervention, der gives i forhold til deres problemer før udskrivelse fra AMA...... studiet er en randomiseret kontrolleret undersøgelse med en og seks måneders opfølgning. Der inkluderes 300 geriatriske patienter, udskrevet fra AMA med bopæl i Københavns Kommune. Intervention: Projektsygeplejersken afholder en struktureret samtale med patienten inden udskrivelsen. Herunder vurderes om......, omfanget af hjælp registreres og der udføres funktionsevnetest (chair-stand-test, håndgrebskraft, Avlunds trætheds- og mobilitetstest, selvvurderet helbredsrelateret livskvalitet SF12, Geriatric Depression Scale DS-5 og Mini Mental State Examination MMSE). Ved baseline anvendes deskriptiv statistik...

  7. Proceedings of the ISES Millennium Solar Forum 2000. 1. ed.

    Energy Technology Data Exchange (ETDEWEB)

    Estrada, Claudio A. [ed.

    2000-07-01

    The ISES Millennium Solar Forum 2000 was organized by the Association Nacional de Energia Solar (ANES) of Mexico, and the International Solar Energy Society (ISES), in collaboration with other national and international organizations from 17 to 22 of September, 2000 in Mexico City. The Scientific-Technical Conference forms the core of this forum. This comprises of 167 papers, which were presented orally and form part of the proceedings. The papers represent the results of research and technological development effort in Renewable Energy reported by professionals and students of 22 countries. Of course, a major component is from Mexico and Latin America. Here you will find useful information on the advances in different fields of Renewable Energy. [Spanish] La Asociacion Nacional de Energia Solar A.C. (ANES) y la International Solar Society (ISES), apoyadas por organizaciones nacionales e internacionales, comprometidas con la promocion de las energias renovables organizaron el ISES Millennium Solar Forum 2000, los dias 17 a 22 de septiembre del 2000 en la Ciudad de Mexico. Como parte medular de este foro se organizo la reunion cientifico-tecnica, en donde se presentaron 167 trabajos, la mayoria de los cuales se incluyen en esta memoria. Estos trabajos representan el esfuerzo en investigacion y desarrollo tecnologico de estudiantes y profesionales de mas de 22 paises, la mayoria de Mexico y America Latina. En esta memoria se encuentran los avances mas relevantes en las distintas areas de especializacion de las energias renovables.

  8. Levetiracetam: review clinica ed economica di un nuovo antiepilettico

    Directory of Open Access Journals (Sweden)

    Orietta Zaniolo

    2004-06-01

    Full Text Available Uncontrolled epilepsy has a significant negative impact on patient’s quality of life, on his emotional well-being and his social functioning. Seizure places an undue economic burden on the patient and community. The increased costs are direct and indirect (e.g.,inpatient care and loss of earnings associated with time lost from work. Levetiracetam is a new antiepileptic drug used as adjuntive therapy in the treatment of refractory epilepsy. Its nonconventional mechanism of action is not completely understood, but preclinical studies suggest that its antiepileptic action.may depend on a reversible, saturable and stereoselective binding site in CNS membranes. In this paper, we review the main clinical and economic data available in the scientific literature. Levetiracetam has a favourable pharmacokinetic profile characterised by rapid and nearly complete absorption, very low potential for drug interactions and a prolonged pharmacodynamic effect that permits twice-daily dosing. Several placebo-controlled clinical trials have demonstrated that its efficacy has enabled many patients who were refractory to treatment with other antiepileptic drugs to achieve long-term seizure freedom; furthermore in levetiracetam trials the frequency of adverse events is low and withdrawal rates are comparable with those of placebo. A cost/effectiveness analysis compared direct medical costs of levetiracetam add-on therapy with maintenance of standard therapy alone within the UK National Health Service. A 1-year dose escalation decision model was set up in refractory patients who failed to respond to two or more other currently available therapies, with seizure freedom selected as the measure of effectiveness. Available pharmacoeconomic data show that the incremental cost of treating patients with levetiracetam is low when compared with the benefits of seizure freedom, at least in the UK. Furthermore, current studies suggest that this antiepileptic drug has a

  9. MicroRaman, PXRD, EDS and microscopic investigation of magnesium calcite biomineral phases. The case of sea urchin biominerals

    Science.gov (United States)

    Borzęcka-Prokop, B.; Wesełucha-Birczyńska, A.; Koszowska, E.

    2007-02-01

    This study concerns Mg-calcite characterization (and in particular molecular structure and microstructural studies of mineral phases) of a sea urchin mineralised test and spines. Sea urchins are spiny sea animals (kingdom Animalia, phylum Echinodermata, class Echinoidea). Microscopic observations, SEM, EDS, PXRD and spectroscopic microRaman methods have been applied to characterize the biomineral parts of the sea urchin. The latter technique is very useful in research of biological systems and especially suitable for monitoring differences within biomineral phases exhibiting varieties of morphological forms. Crystalline magnesium calcium carbonate, Mg xCa 1- xCO 3 (magnesian calcite; space group R-3 cH; a = 4.9594(8) Å, c = 16.886(6) Å), has been identified as the predominant biomineral component.

  10. Racial Profiling as Collective Definition

    Directory of Open Access Journals (Sweden)

    Trevor G. Gardner

    2014-09-01

    Full Text Available Economists and other interested academics have committed significant time and effort to developing a set of circumstances under which an intelligent and circumspect form of racial profiling can serve as an effective tool in crime finding–the specific objective of finding criminal activity afoot. In turn, anti-profiling advocates tend to focus on the immediate efficacy of the practice, the morality of the practice, and/or the legality of the practice. However, the tenor of this opposition invites racial profiling proponents to develop more surgical profiling techniques to employ in crime finding. In the article, I review the literature on group distinction to discern its relevance to the practice and study of racial profiling. I argue that the costs of racial profiling extend beyond inefficient policing and the humiliation of law-abiding minority pedestrians and drivers. Racial profiling is simultaneously a process of perception and articulation of relative human characteristics (both positive and negative; it binds and reifies the concepts of race and criminality, fixing them into the subconscious of the profiled, the profiler, and society at large.

  11. Improved Early Detection of Sepsis in the ED With a Novel Monocyte Distribution Width Biomarker.

    Science.gov (United States)

    Crouser, Elliott D; Parrillo, Joseph E; Seymour, Christopher; Angus, Derek C; Bicking, Keri; Tejidor, Liliana; Magari, Robert; Careaga, Diana; Williams, JoAnna; Closser, Douglas R; Samoszuk, Michael; Herren, Luke; Robart, Emily; Chaves, Fernando

    2017-09-01

    Sepsis most often presents to the ED, and delayed detection is harmful. WBC count is often used to detect sepsis, but changes in WBC count size also correspond to sepsis. We sought to determine if volume increases of circulating immune cells add value to the WBC count for early sepsis detection in the ED. A blinded, prospective cohort study was conducted in two different ED populations within a large academic hospital. Neutrophil and monocyte volume parameters were measured in conjunction with routine CBC testing on a UniCel DxH 800 analyzer at the time of ED admission and were evaluated for the detection of sepsis. There were 1,320 subjects in the ED consecutively enrolled and categorized as control subjects (n = 879) and those with systemic inflammatory response syndrome (SIRS) (n = 203), infection (n = 140), or sepsis (n = 98). Compared with other parameters, monocyte distribution width (MDW) best discriminated sepsis from all other conditions (area under the curve [AUC], 0.79; 95% CI, 0.73-0.84; sensitivity, 0.77; specificity, 0.73; MDW threshold, 20.50), sepsis from SIRS (AUC, 0.74; 95% CI, 0.67-0.84), and severe sepsis from noninfected patients in the ED (AUC, 0.88; 95% CI, 0.75-0.99; negative predictive value, 99%). The added value of MDW to WBC count was statistically significant (AUC, 0.89 for MDW + WBC vs 0.81 for WBC alone; P sepsis compared with WBC count alone at the time of admission in the ED. ClinicalTrials.gov; No.: NCT02232750; URL: www.clinicaltrials.gov. Copyright © 2017 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

  12. Trends in Hospital Admission and Surgical Procedures Following ED visits for Diverticulitis.

    Science.gov (United States)

    Greenwood-Ericksen, Margaret B; Havens, Joaquim M; Ma, Jiemin; Weissman, Joel S; Schuur, Jeremiah D

    2016-07-01

    Diverticulitis is a common diagnosis in the emergency department (ED). Outpatient management of diverticulitis is safe in selected patients, yet the rates of admission and surgical procedures following ED visits for diverticulitis are unknown, as are the predictive patient characteristics. Our goal is to describe trends in admission and surgical procedures following ED visits for diverticulitis, and to determine which patient characteristics predict admission. : We performed a cross-sectional descriptive analysis using data on ED visits from 2006-2011 to determine change in admission and surgical patterns over time. The Nationwide Emergency Department Sample database, a nationally representative administrative claims dataset, was used to analyze ED visits for diverticulitis. We included patients with a principal diagnosis of diverticulitis (ICD-9 codes 562.11, 562.13). We analyzed the rate of admission and surgery in all admitted patients and in low-risk patients, defined as age diverticulitis. Fryom 2006 to 2011 ED visits for diverticulitis increased by 21.3% from 238,248 to 302,612, while the admission rate decreased from 55.7% to 48.5% (-7.2%, 95% CI [-7.78 to -6.62]; pdiverticulitis was independently associated with male gender, comorbid illnesses, higher income and commercial health insurance. The surgical rate decreased from 6.5% in 2006 to 4.7% in 2011 (-1.8%, 95% CI [-2.1 to -1.5]; pdiverticulitis increased, while ED admission rates and surgical rates declined, with comorbidity, sociodemographic factors predicting hospitalization. Future work should focus on determining if these differences reflect increased disease prevalence, increased diagnosis, or changes in management.

  13. Prevalence of Diabetes Mellitus (DM) in a population of men affected by Erectile Dysfunction (ED).

    Science.gov (United States)

    Mazzilli, R; Elia, J; Delfino, M; Benedetti, F; Scordovillo, G; Mazzilli, F

    2015-01-01

    A) to evaluate the prevalence of patients affected by Diabetes Mellitus (DM) in a population of men with Erectile Dysfunction (ED); B) to define the epidemiological, biochemical and therapeutic aspects. N.934 subjects referred at our Andrology Unit for ED were studied. The diagnosis of ED was evaluated using the IIEF-5 questionnaire (Total score ≤21). The prevalence of subjects affected by DM in a population of men with ED was 19.5% (182/934). The age ranges were: ≥55 years (108/182; 59.3%); ≥40diabetic treatment. In n.125/182 cases (68.7%) the ED onset followed the diagnosis of DM; in n.34/182 cases (18.7%) it appeared at the same time; and in n.23/182 cases (12.6%) appeared before DM diagnosis. in n.18/182 subjects (9.9%) there was a concomitant hypotestosteronemia; these patients were treated only with testosterone replacement; this treatment was efficacious (IIEF-5 total score ≥22) in 8/18 subjects (44.4%). In n.146/182 subjects (80.2%) a treatment with PDE5-i was given. Of these 146 subjects, the therapy was given "on demand" to 108 subjects (efficacy in 50.9%; 55/108) and "once a day" to the remaining 38 subjects (efficacy 63.1%, 24/38) (p=0.428, n.s.). N.15/182 subjects (8.2%) were treated with intracavernous injections of Alprostadil (efficacy in 8/15, 53.3%). In n.3/182 subjects (1.6%) a penile prosthesis was implanted. DM is one of the most frequent organic causes of ED; there were many strategies to treat this symptom without interfering with the antidiabetic treatment. Finally, ED can be predictive of DM.

  14. The EPIFARM study: an observational study in 574 community pharmacies in Spain characterizing patient profiles of men asking for erectile dysfunction medication.

    Science.gov (United States)

    Morales, Antonio Martín; Ibáñez, José; Machuca, Manuel; Pol-Yanguas, Emilio; Schnetzler, Gabriel; Renedo, Virginia Pascual

    2010-09-01

    Community pharmacists may be an important first point of contact for erectile dysfunction (ED) patients, but to date there are no reports of the characteristics of men approaching pharmacists for ED advice or treatment. To characterize the profiles of men with and without phosphodiesterase-5 inhibitors (PDE5i) prescription asking for ED treatment at the pharmacy. A multicenter, observational, cross-sectional study was conducted in Spanish community pharmacies September-November 2008. Of men asking for ED advice or treatment, each investigator recruited one with and one without PDE5i prescription. Study pharmacists completed a questionnaire of patient demographic, clinical, and behavioural data including the Sexual Health Inventory for Men. Demographic characteristics and responses to questionnaires. Five hundred and seventy-four pharmacists recruited 1,147 patients; 1,113 were included for analysis. There were no statistical differences between the groups regarding weight, hypertension, diabetes mellitus, hypercholesterolemia, dyslipidemia, depression, or stress. There were no statistical differences in severity of ED (P=0.7892) or proportion of men without ED in each group (P=0.5755). ED symptoms had been present for a mean of 26 months in both groups before first consultation with a healthcare professional. The visit to the pharmacy was the first discussion about ED for 60.2% of the nonprescription group, and 50% of those who had previously discussed ED had done so with a pharmacist in the first instance. In the nonprescription group, 85.1% of men asked for a PDE5i. Many men approached a community pharmacist for ED treatment and those with and without a PDE5i prescription had an equivalent ED severity and comorbidity profile. Community pharmacists should be trained in current concepts underlying the diagnosis and management of ED to enable them to educate men and encourage them to seek further medical care, increasing the chance of early detection of undiagnosed

  15. Racial Profiling as Collective Definition

    OpenAIRE

    Trevor G. Gardner

    2014-01-01

    Economists and other interested academics have committed significant time and effort to developing a set of circumstances under which an intelligent and circumspect form of racial profiling can serve as an effective tool in crime finding-the specific objective of finding criminal activity afoot. In turn, anti-profiling advocates tend to focus on the immediate efficacy of the practice, the morality of the practice, and/or the legality of the practice. However, the tenor of this opposition invi...

  16. Pleistocene events recrodEd. by shallow seismic profiling over the continental shelf off Krishna-Godavari Deltas

    Digital Repository Service at National Institute of Oceanography (India)

    Rao, T.C.S.

    stream_size 11 stream_content_type text/plain stream_name Quatern_Delta_India_1991_153.pdf.txt stream_source_info Quatern_Delta_India_1991_153.pdf.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset=ISO-8859-1 ...

  17. Suicide Prevention in an Emergency Department Population: The ED-SAFE Study.

    Science.gov (United States)

    Miller, Ivan W; Camargo, Carlos A; Arias, Sarah A; Sullivan, Ashley F; Allen, Michael H; Goldstein, Amy B; Manton, Anne P; Espinola, Janice A; Jones, Richard; Hasegawa, Kohei; Boudreaux, Edwin D

    2017-06-01

    Suicide is a leading cause of deaths in the United States. Although the emergency department (ED) is an opportune setting for initiating suicide prevention efforts, ED-initiated suicide prevention interventions remain underdeveloped. To determine whether an ED-initiated intervention reduces subsequent suicidal behavior. This multicenter study of 8 EDs in the United States enrolled adults with a recent suicide attempt or ideation and was composed of 3 sequential phases: (1) a treatment as usual (TAU) phase from August 2010 to December 2011, (2) a universal screening (screening) phase from September 2011 to December 2012, and (3) a universal screening plus intervention (intervention) phase from July 2012 to November 2013. Screening consisted of universal suicide risk screening. The intervention phase consisted of universal screening plus an intervention, which included secondary suicide risk screening by the ED physician, discharge resources, and post-ED telephone calls focused on reducing suicide risk. The primary outcome was suicide attempts (nonfatal and fatal) over the 52-week follow-up period. The proportion and total number of attempts were analyzed. A total of 1376 participants were recruited, including 769 females (55.9%) with a median (interquartile range) age of 37 (26-47) years. A total of 288 participants (20.9%) made at least 1 suicide attempt, and there were 548 total suicide attempts among participants. There were no significant differences in risk reduction between the TAU and screening phases (23% vs 22%, respectively). However, compared with the TAU phase, patients in the intervention phase showed a 5% absolute reduction in suicide attempt risk (23% vs 18%), with a relative risk reduction of 20%. Participants in the intervention phase had 30% fewer total suicide attempts than participants in the TAU phase. Negative binomial regression analysis indicated that the participants in the intervention phase had significantly fewer total suicide attempts

  18. Minnesota Multiphasic Personality Inventory: two automated forms.

    Science.gov (United States)

    Kewman, D G; Lieverman, H J

    1982-07-01

    Two automated forms of the MMPI have been developed which are of particular utility in a rehabilitation setting with some individuals who have impairment of upper extremity functioning or mild visual problems. One form involving the sorting of IBM punch cards with printed questions into true and false piles, has been adapted and improved for scoring, profile generation and storage using a high speed campus computational facility. The 2nd form utilizes a small microcomputer for individual administration, scoring, profile generation and storage of information.

  19. The Relationship Between the Use of a Worksite Medical Home and ED Visits or Hospitalizations

    Directory of Open Access Journals (Sweden)

    Marissa Stroo BS

    2015-10-01

    Full Text Available Worksite medical homes may be a good model for improving employee health. The aim of this study was to compare the likelihood of being seen in the emergency department (ED or being hospitalized by level of use (no use, occasional use, or primary care of a worksite medical home, overall and by type of user (employee, adult dependent, or pediatric dependent. This was a retrospective analysis of claims data, using covariate-adjusted logistic regression models for ED visits and inpatient hospitalizations. Secondary data for the years 2006 to 2008 from a company that offers an on-site health care center (HCC were used. Analyses were based on a data set that combines health plan claims and human resources demographic data. Overall, people who did not use the HCC were more likely to be seen in the ED (adjusted odds ratio [OR] = 1.20, 95% confidence interval or CI [1.06, 1.37], P = .005 or to be hospitalized (adjusted OR = 1.58; 95% CI [1.34, 1.86]; P < .0001 compared with those who used the HCC for primary care. Both ED visits and hospitalizations for employees and dependents in this study were lower among those who used the worksite medical home for primary care. Worksite medical homes can improve chronic disease management and thus reduce ED visits and hospitalizations. These findings contribute to growing evidence that worksite medical homes are potentially cost-effective.

  20. Factors affecting stress in emergency medicine residents while working in the ED.

    Science.gov (United States)

    Wrenn, Keith; Lorenzen, Brent; Jones, Ian; Zhou, Chuan; Aronsky, Dominik

    2010-10-01

    The aim of this study was to identify factors other than work hours in the emergency department (ED) work environment contributing to resident stress. This study involved a prospective cohort evaluation of emergency medicine residents in the ED. Twelve surveys were collected from 18 subjects, 4 each from the day, evening, and night shifts. The Perceived Stress Questionnaire and a visual analog stress scale were administered. Data collected included the shift number of a given consecutive sequence of shifts, number of procedures performed, number of adverse events, average age of the patients seen by the resident, triage nurse-assigned acuities of the patients seen by the resident during the shift, the number of patients seen during a shift, the number of patients admitted by the resident during the shift, anticipated overtime after a shift, and shift-specific metrics related to overcrowding, including average waiting room time both for the individual residents and for all patients, average waiting room count for all patients, and average occupancy of the ED for all patients. Among the 216 studied shifts, there was considerable variability in stress both within and between residents. In the multivariate mixed-effect regression analysis, only anticipated overtime and process failures were correlated with stress. Factors related to ED overcrowding had no significant effect on resident stress. Resident stress was most impacted by anticipation of overtime and adverse events. Overcrowding in the ED and traditional measures of workload did not seem to affect stress as much. Copyright © 2010 Elsevier Inc. All rights reserved.

  1. Hardiness Mediates Stress and Impact Level in ED Nurses Who Experienced a Violent Event.

    Science.gov (United States)

    Park, Jin Hee; Lee, Eun Nam; Kong, Kyung Ran; Jang, Moon Jung

    2017-11-01

    This secondary analysis examined the mediating effect of hardiness between stress and impact level in ED nurses who experienced a violent event. This correlational study was conducted from June to August 2014. We used the visual analog scale to measure stress level, the Impact of Event Scale-Revised to measure impact level after the violent event, and the Dispositional Resilience Scale to measure hardiness. We then analyzed mediating effects with the Sobel test. Data were collected in 31 emergency medical centers located in B city in Korea. Data from 321 ED nurses who experienced a violent event were analyzed. Most nurses (91.9%) were women, with a mean age of 28.73 years. The main outcome measure was the mediating effect of hardiness between stress and impact level after ED nurses experienced violence. We found that both violence-related stress (B = 0.22, P level from a violent event. Based on results of a Sobel test, hardiness partially mediated the relationship between violence-related stress and impact level from a violent event (Z = 2.03, P = .044). Hardiness had an effect on reducing the impact level of ED nurses who had experienced a violent event and had a mediating role in mitigating their stress. Therefore, we recommend the development of an intervention program that emphasizes the improvement of hardiness in ED nurses. Copyright © 2017 Emergency Nurses Association. Published by Elsevier Inc. All rights reserved.

  2. Nanostructure and Composition of Tribo-Boundary Films Formed in Ionic Liquid Lubrication

    Energy Technology Data Exchange (ETDEWEB)

    Qu, Jun [ORNL; Chi, Miaofang [ORNL; Meyer III, Harry M [ORNL; Blau, Peter Julian [ORNL; Dai, Sheng [ORNL; Luo, Huimin [ORNL

    2011-01-01

    Since the idea of using ionic liquids (ILs) as lubricants was raised in 2001, many studies have been conducted in this area and results have demonstrated superior lubricating performance for a variety of ionic liquids. It is widely believed that tribochemical reactions occur between the metal surface and the IL during the wear process to form a protective tribo-boundary film on the contact area that reduces friction and wear. However, the study of this critical boundary film has been limited to top surface two-dimensional topography examination and chemical analysis in the literature. A more comprehensive characterization is needed to help understand the film formation process and the lubricating mechanism. This study demonstrated a multi-technique three-dimensional approach to characterize the IL-formed boundary films, including top surface morphology examination, cross section nanostructure characterization, and layered chemical analysis. Characterization was carried out on both ferrous and aluminum surfaces lubricated by an ammonium IL. The focused-ion-beam (FIB) technique enabled TEM/EDS examination on the cross section of the boundary film to provide direct measurement of the film thickness, visualization of the nanostructure, and analysis of composition. In addition, composition-depth profiles were generated using XPS aided by ion-sputtering to reveal the composition change at different levels of the boundary film to investigate the film formation process.

  3. Ion Beam Synthesis of Ge Nanowires. rev. ed.

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, T.

    2001-01-01

    The formation of Ge nanowires in V-grooves has been studied experimentally as well as theoretically. As substrate oxide covered Si V-grooves were used formed by anisotropic etching of (001)Si wafers and subsequent oxidation of their surface. Implantation of 1 x 10{sup 17} Ge{sup +}cm{sup -2} at 70 keV was carried out into the oxide layer covering the V-grooves. Ion irradiation induces shape changes of the V-grooves, which are captured in a novel continuum model of surface evolution. It describes theoretically the effects of sputtering, redeposition of sputtered atoms, and swelling. Thereby, the time evolution of the target surface is determined by a nonlinear integro-differential equation, which was solved numerically for the V-groove geometry. A very good agreement is achieved for the predicted surface shape and the shape observed in XTEM images. Surprisingly, the model predicts material (Si, O, Ge) transport into the V-groove bottom which also suggests an Ge accumulation there proven by STEM-EDX investigations. In this Ge rich bottom region, subsequent annealing in N{sub 2} atmosphere results in the formation of a nanowire by coalescence of Ge precipitates shown by XTEM images. The process of phase separation during the nanowire growth was studied by means of kinetic 3D lattice Monte-Carlo simulations. These simulations also indicate the disintegration of continuous wires into droplets mediated by thermal fluctuations. Energy considerations have identified a fragmentation threshold and a lower boundary for the droplet radii which were confirmed by the Monte Carlo simulation. The here given results indicate the possibility of achieving nanowires being several nanometers wide by further growth optimizations as well as chains of equally spaced clusters with nearly uniform diameter. (orig.)

  4. LA CORRETTA VALORIZZAZIONE DEI RIFIUTI AGRICOLI ED AGROINDUSTRIALI

    Directory of Open Access Journals (Sweden)

    Francesco Saverio Nesci

    2014-12-01

    Full Text Available Farming and agro-industrial waste can represent a resource when destined to energy production and they can contribute to reduce greenhouse gas emission, to improve energetic efficiency and increase renewable energies. 6 stations are already working in Calabria for agro-zootechnical biomasses and agro-industrial waste transformation, in compliance with 91/676/CEE, Nitrates Directive, then D.L. 152/99 and D.M. 7 April 2006, redefined by D.M. 6-7-2012 It reduced incentives, with the aim of implementing small sized stations powered by recyclable byproducts, which are easier to manage especially in the form of consortium by medium and small sized companies that would otherwise be excluded from the market. An appropriate use of pruning waste would also mean turning a problem into an opportunity if, instead of burning it and producing high levels of CO2 (as forbidden by D.L. “terra dei fuochi” it could be destined to produce a new kind of power source, biochar, with a carbon negative function. Concerning the market of carbon credits derivable from pruning waste and from the production of more than 130.000 t of biochar (which, differently from the forestry sector, hasn’t been accepted in farming yet, the potential wealth on the regional territory could vary from 5 to 11 million € according to the set price. Establishing a more competitive and sustainable source of energy is one of the most important challenges that our Country has to face today. This sector plays a key role in the economic development of the Country, not only as a distinctive feature of low cost energy production, limited impact on environment and high utilization, but also as an element of growth per se, with a boost in ecologic economy thanks to a predominant use of renewable resources, recycling and curbing domestic or industrial waste, according to Green Economy parameters.

  5. MPI Profiling

    Energy Technology Data Exchange (ETDEWEB)

    Han, D K; Jones, T R

    2005-02-11

    The Message Passing Interface (MPI) is the de facto message-passing standard for massively parallel programs. It is often the case that application performance is a crucial factor, especially for solving grand challenge problems. While there have been many studies on the scalability of applications, there have not been many focusing on the specific types of MPI calls being made and their impact on application performance. Using a profiling tool called mpiP, a large spectrum of parallel scientific applications were surveyed and their performance results analyzed.

  6. The German energy marketplace. 7. tot. rev. ed.; Energiemarkt Deutschland

    Energy Technology Data Exchange (ETDEWEB)

    Schiffer, H.W. [Rheinbraun AG, Koeln (Germany)

    1999-07-01

    The book gives a comprehensive survey of the German marketplace for energy, based on an initial analysis and description of the organisational structures of the home markets for the various forms of tradeable energy sources and energy, as well as the respective pricing mechanisms for mineral oil, browncoal, coal, natural gas and electricity. The characteristic facts picturing the marketplace are given in a total of 103 tables and 95 graphs, showing the situation as of June 199, and last available figures of 1998. About 100 energy companies are characterised including information on shareholders. The two energy price crises of 1973 and 19879/80 as well as the deep-cutting changes brought about in the eastern federal states after the German unification are analysed in terms of their impact on total energy comsumption in Germany, broken down into sectors: Industry, traffic, households, and trade/business/services. This information is enhanced by a synopsis including the most recent forecasts of future energy consumption. The major lines of orientation of the federal government's energy policy and the backbones of the ecological tax reform are reviewed in brief. Finally, the full texts of relevant EU legislation are reproduced (EU Directives), and those of the German act for reform of the energy sector and the amendment of the law against restraints of competition. (orig./CB) [German] Das Buch vermittelt einen geschlossenen Ueberblick ueber den Energiemarkt der Bundesrepublik Deutschland. Die Grundlage bildet eine Darstellung der Organisationsstruktur der Energieteilmaerkte sowie der Preisbildungsmechanismen bei Mineraloel, Braunkohle, Steinkohle, Erdgas und Elektrizitaet. Die wichtigsten Fakten zur Charakterisierung des Energiemarktes sind - unter Ausweis der Zahlen fuer das Jahr 1998 - in 103 Tabellen und 95 Schaubildern mit Stand Juni 1999 zusammengefasst. Fuer etwa 100 Energieunternehmen sind die Anteilseigner ausgewiesen. Die beiden Energiepreiskrisen 1973

  7. Towards effective solid form screening.

    Science.gov (United States)

    Allesø, Morten; Tian, Fang; Cornett, Claus; Rantanen, Jukka

    2010-09-01

    Solid form screening is commonly performed using solvent-based crystallizations. However, less attention is paid to the role of secondary manufacturing, during which process-induced transformations of the active pharmaceutical ingredient (API) may occur, and potentially a new solid form may be discovered. In this study a new approach for effective solid form screening is presented. The technology combines well-plate-based crystallizations with miniaturized processing equipment, mimicking essential unit operations. Process-induced stresses (heat, solvent, shear, pressure) can be introduced directly to the well-plate unit. Theophylline and nifedipine were used as model compounds. Small-scale wet massing of theophylline resulted in an anhydrate-to-monohydrate transformation, followed by dehydration upon drying at 60 degrees C. Amorphous nifedipine was subjected to small-scale milling and compaction. Kinetic profiling of the milling operation enabled the detection of an intermediate, metastable polymorph (beta form), while the stable polymorph (alpha form) was the predominant form after 20 min of milling. Compaction of amorphous nifedipine at 100 MPa resulted in a complete conversion into the stable polymorph. The reported expanded approach is expected to maximize the outcome of solid form screening with minimal consumption of the compound of interest.

  8. Patient-centered transfer process for patients admitted through the ED boosts satisfaction, improves safety.

    Science.gov (United States)

    2013-02-01

    To improve safety and patient flow, administrators at Hallmark Health System, based in Melrose, MA, implemented a new patient-centered transfer process for patients admitted through the ED at the health system's two hospitals. Under the new approach, inpatient nurses come down to the ED to take reports on new patients in a process that includes the ED care team as well as family members. The inpatient nurses then accompany the patients up to their designated floors. Since the new patient-transfer process was implemented in June 2012, patient satisfaction has increased by at least one point on patient satisfaction surveys. Administrators anticipate that medical errors or omissions related to the handoff process will show a drop of at least 50%, when data is tabulated.

  9. "Etica ed Estetica sono tutt’uno" Riflessioni su TLP 6.421

    Directory of Open Access Journals (Sweden)

    Gabriele Tomasi

    2011-01-01

    Full Text Available Per il primo Wittgenstein etica ed estetica erano tutt’uno. Scopo del saggio è fornire un’interpretazione di questa concezione. Esaminando il modo in cui è proposta nel Tractatus e considerando alcune annotazioni dei Quaderni 1914-1916 si evidenzia che l’unità di etica ed estetica è in un modo di vedere il mondo per cui esso non appare come fonte di limitazione. L’etica è un’estensione al mondo - alla vita - della capacità di conferire significato che nell’arte si realizza nei riguardi di oggetti particolari. Affermando l’unità di etica ed estetica Wittgenstein attira l’attenzione sul fatto che la radice dell’etica è in un certo modo di vedere le cose, in un atteggiamento verso la vita. Si tratta della prospettiva di un valore non connesso a come il mondo è e che è evocato dalla meraviglia per l’esistenza del mondo.

  10. Impact of 40 years of technology advances on EDS system performance.

    Science.gov (United States)

    McCarthy, Jon; Friel, John; Camus, Patrick

    2009-12-01

    The rapid advance and falling costs of computing power and data storage during the last 40 years have greatly enhanced the data reduction speed and analytical capacity of energy dispersive spectroscopy (EDS) systems. At the same time, the solid state X-ray detector [until recently, the Si(Li) diode] has seen performance increases due to the use of advanced materials and processing techniques. In addition, the performance of the electronic components (field effect transistor, preamp, and pulse processor) of an EDS system has been constantly improved. These technology advances have resulted in improved spectral quality, excellent light element detection, and increased count rate performance. The results have been truly remarkable and driven by the needs of the analyst. This article will summarize the progress made in these areas in the last 40 years and make a brief reference to prospects for future development in EDS system performance.

  11. Performing elemental microanalysis with high accuracy and high precision by scanning electron microscopy/silicon drift detector energy-dispersive X-ray spectrometry (SEM/SDD-EDS).

    Science.gov (United States)

    Newbury, Dale E; Ritchie, Nicholas W M

    Electron-excited X-ray microanalysis performed in the scanning electron microscope with energy-dispersive X-ray spectrometry (EDS) is a core technique for characterization of the microstructure of materials. The recent advances in EDS performance with the silicon drift detector (SDD) enable accuracy and precision equivalent to that of the high spectral resolution wavelength-dispersive spectrometer employed on the electron probe microanalyzer platform. SDD-EDS throughput, resolution, and stability provide practical operating conditions for measurement of high-count spectra that form the basis for peak fitting procedures that recover the characteristic peak intensities even for elemental combination where severe peak overlaps occur, such PbS, MoS2, BaTiO3, SrWO4, and WSi2. Accurate analyses are also demonstrated for interferences involving large concentration ratios: a major constituent on a minor constituent (Ba at 0.4299 mass fraction on Ti at 0.0180) and a major constituent on a trace constituent (Ba at 0.2194 on Ce at 0.00407; Si at 0.1145 on Ta at 0.0041). Accurate analyses of low atomic number elements, C, N, O, and F, are demonstrated. Measurement of trace constituents with limits of detection below 0.001 mass fraction (1000 ppm) is possible within a practical measurement time of 500 s.

  12. Benzodiazepine-opioid co-prescribing in a national probability sample of ED encounters.

    Science.gov (United States)

    Kim, Howard S; McCarthy, Danielle M; Mark Courtney, D; Lank, Patrick M; Lambert, Bruce L

    2017-03-01

    Benzodiazepine-opioid combination therapy is potentially harmful due to the risk of synergistic respiratory depression, and the rate of death due to benzodiazepine-opioid overdose is increasing. Little is known about the prevalence and characteristics of benzodiazepine-opioid co-prescribing from the ED setting. Secondary analysis of data from the National Hospital Ambulatory Medical Care Survey, using sample weights to generate population estimates. The primary objective was to describe the annual prevalence of benzodiazepine-opioid co-prescribing from 2006 to 2012, using 95% confidence intervals (95% CI) to compare adjacent years. The secondary objective was to compare characteristics of ED encounters receiving a benzodiazepine-opioid co-prescription versus those receiving an opioid prescription alone, using a multivariable logistic regression. The prevalence of benzodiazepine-opioid co-prescribing did not significantly change from 2006 to 2012. During this period, 2.7% (95% CI: 2.5-2.8%) of ED encounters prescribed an opioid were also prescribed a benzodiazepine. Relative to encounters receiving an opioid prescription alone, encounters receiving a co-prescription were more likely to represent a follow-up rather than initial visit (Odds Ratio [OR] 1.52), receive more medications (OR 1.41) and fewer procedures (OR 0.48) while in the ED, and more likely to have a diagnosis related to mental disorder (OR 20.60) or musculoskeletal problem (OR 3.71). From 2006 to 2012, almost 3% of all ED encounters receiving an opioid prescription also received a benzodiazepine co-prescription. The odds of benzodiazepine-opioid co-prescribing were significantly higher in ED encounters representing a follow-up visit and in diagnoses relating to a mental disorder or musculoskeletal problem. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. Multidisciplinary intervention decreases the use of opioid medication discharge packs from 2 urban EDs.

    Science.gov (United States)

    Gugelmann, Hallam; Shofer, Frances S; Meisel, Zachary F; Perrone, Jeanmarie

    2013-09-01

    Prescription opioid overdoses and deaths constitute a public health epidemic, and recent studies show that emergency department (ED) prescribers may contribute to this crisis. We hypothesized that a multidisciplinary educational intervention would decrease ED opioid packs dispensed at discharge. This prospective study implemented a "bundle" of interdisciplinary educational modalities: lectures, journal clubs, case discussions, and an electronic medical record decision support tool. Implementation occurred in 2 urban EDs in the same health system at different times ("affiliate," September 2011; "primary," January 2012) to better distinguish its effects. The primary outcome was preintervention/postintervention change in opioid discharge packs dispensed to all patients treated and discharged through August 2012 and was assessed by 2-way analysis of variance. The secondary outcome was bivariate analysis (using Fisher exact test) of change in opioid dispensing among patients with known risk factors for prescription opioid dependence: age less than 65 years, history of substance abuse, chronic pain, or psychiatric disorders. A total of 71,512 and 45,746 patients were evaluated and discharged from primary and affiliate EDs, respectively. Orders for opioid discharge packs decreased from 13.9% to 8.4% and 4.7% to 1.9% at the primary and affiliate hospitals (P opioid dependence at the primary ED decreased from 21.8% to 13.9%. A staged, multidisciplinary intervention targeting nurses, residents, nurse practitioners, and attending physicians was associated with decreased orders for opioid discharge packs in 2 urban EDs. Opioid discharge pack orders decreased slightly more among patients with risk factors for prescription opioid dependence. © 2013.

  14. PopED lite: An optimal design software for preclinical pharmacokinetic and pharmacodynamic studies.

    Science.gov (United States)

    Aoki, Yasunori; Sundqvist, Monika; Hooker, Andrew C; Gennemark, Peter

    2016-04-01

    Optimal experimental design approaches are seldom used in preclinical drug discovery. The objective is to develop an optimal design software tool specifically designed for preclinical applications in order to increase the efficiency of drug discovery in vivo studies. Several realistic experimental design case studies were collected and many preclinical experimental teams were consulted to determine the design goal of the software tool. The tool obtains an optimized experimental design by solving a constrained optimization problem, where each experimental design is evaluated using some function of the Fisher Information Matrix. The software was implemented in C++ using the Qt framework to assure a responsive user-software interaction through a rich graphical user interface, and at the same time, achieving the desired computational speed. In addition, a discrete global optimization algorithm was developed and implemented. The software design goals were simplicity, speed and intuition. Based on these design goals, we have developed the publicly available software PopED lite (http://www.bluetree.me/PopED_lite). Optimization computation was on average, over 14 test problems, 30 times faster in PopED lite compared to an already existing optimal design software tool. PopED lite is now used in real drug discovery projects and a few of these case studies are presented in this paper. PopED lite is designed to be simple, fast and intuitive. Simple, to give many users access to basic optimal design calculations. Fast, to fit a short design-execution cycle and allow interactive experimental design (test one design, discuss proposed design, test another design, etc). Intuitive, so that the input to and output from the software tool can easily be understood by users without knowledge of the theory of optimal design. In this way, PopED lite is highly useful in practice and complements existing tools. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  15. Macrofauna edáfica asociada con sistemas agroforestales en la Amazonía Colombiana

    OpenAIRE

    Juan Carlos Suárez Salazar; Ervin Humprey Duran Bautista; Gelber Rosas Patiño

    2015-01-01

    La densidad, riqueza y diversidad de la macrofauna edáfica son afectadas, entre otros factores, por la configuración de los agroecosistemas y la estacionalidad de la precipitación. Con el fin de evaluar estos efectos en mayo y noviembre de 2011, correspondientes a épocas de máxima y mínima precipitación, respectivamente, se realizaron estudios sobre la composición de la macrofauna edáfica asociada con los arreglos agroforestales ubicados en el Centro de Investigaciones Macagual Cesar Augusto ...

  16. Warning: are you prepared to lose your ED after a natural disaster?

    Science.gov (United States)

    2001-10-01

    Natural catastrophes that can lead to loss of the ED itself are often overlooked in disaster plans and drills. Plans should address evacuation of patients, including transportation and equipment to take, and drills should include these scenarios. You should have alternatives to cope with loss of power and communications, such as oxygen-powered backup generators. To prepare for a deluge of individuals coming to the ED after a disaster, decide how to utilize volunteers, and limit access by using disaster identification vests. New Environment of Care standards from the Joint Commission on Accreditation of Healthcare Organizations require you to perform a hazard and vulnerability analysis.

  17. Planning a brand new ED? Study up on acoustics, air quality, and patient wish-lists.

    Science.gov (United States)

    2012-01-01

    Hospitals planning to construct new EDs have a golden opportunity to integrate designs and materials that can please both patients and providers. Experts say attention to acoustics, privacy, and air quality can lower stress levels and boost satisfaction. Further, designs that prioritize efficient work flows get high marks from providers. Experts advise hospital leaders to get considerable input from patients before designing a new ED facility. Privacy, quiet, and a connection to nature are top priorities for patients. Use design to enhance patient flow.

  18. G. L. Castelli, principe di Torremuzza, numismatico ed antichista ad Halaesa Archonidea

    Directory of Open Access Journals (Sweden)

    Antonino Crisà

    2009-05-01

    Full Text Available G. L. Castelli (1727-1792, principe di Torremuzza, fu uno dei massimi esponenti dell’antiquaria siciliana del XVIII secolo. Questo contributo esamina l’attività di ricerca di Castelli, interessato alla monetazione ed alle evidenze archeologiche di Halaesa Archonidea, oggi identificata nei pressi di Tusa (ME. È proposta un’analisi degli scritti di Castelli inerenti queste tematiche, valutandone criticamente l’importanza secondo le istanze della ricerca antiquaria. Certamente è emerso il profilo di un antichista dai poliedrici interessi, da considerarsi il fondatore degli studi numismatici ed archeologici moderni dell’antica Halaesa.

  19. Is your ED a medical department or a business? Survey says...both.

    Science.gov (United States)

    2009-07-01

    Taking a solid business-like approach to the management of your ED involves--but is certainly not limited to--getting a handle on revenues and expenses. Here are a few strategies some ED managers say help them run a tighter, and better, ship: Have a clinical audit specialist review charts, and have a clerical person "check the checker." Use a "cultural fit" interview with prospective staff members to ensure you're on the same page when it comes to service. Develop a charge structure with numerical values for clinical activities and services, to help ensure optimal reimbursement.

  20. SEM, EDS, PL and absorbance study of CdTe thin films grown by CSS method

    Energy Technology Data Exchange (ETDEWEB)

    Hernandez-Torres, M.E.; Silva-Gonzalez, R.; Gracia-Jimenez, J.M. [Instituto de Fisica, BUAP, Apdo. Postal J-48, San Manuel, 72570 Puebla, Pue. (Mexico); Casarrubias-Segura, G. [CIE- UNAM, 62580 Temixco, Morelos (Mexico)

    2006-09-22

    Oxygen-doped CdTe films were grown on conducting glass substrates by the close spaced sublimation (CSS) method and characterized using SEM, EDS, photoluminescence (PL) and absorbance. A significant change in the polycrystalline morphology is observed when the oxygen proportion is increased in the deposition atmosphere. The EDS analysis showed that all samples are nonstoichiometric with excess Te. The PL spectra show emission bands associated with Te vacancies (V{sub Te}), whose intensities decrease as the oxygen proportion in the CSS chamber is increased. The oxygen impurities occupy Te vacancies and modify the surfaces states, improving the nonradiative process. (author)

  1. AB162. Is it feasible to apply a new concept of erectile dysfunction syndrome (EDS) in clinical practice?

    OpenAIRE

    Chen, Jun; Zhang, Bin; Wen, Jiaming

    2014-01-01

    How to understand the erectile function? How to define erectile dysfunction? In general, erectile function is evaluated by the quality of penile erection. If penis shows good erection, we think erectile function is normal. Otherwise, erectile dysfunction occurs. This concept is reflected in the definition of erectile dysfunction (ED). ED is defined as the persistent inability to attain and maintain an erection sufficient to permit satisfactory sexual performance. From the definition of ED, it...

  2. On good ETOL forms

    DEFF Research Database (Denmark)

    Skyum, Sven

    1978-01-01

    This paper continues the study of ETOL forms and good EOL forms done by Maurer, Salomaa and Wood. It is proven that binary very complete ETOL forms exist, good synchronized ETOL forms exist and that no propagating or synchronized ETOL form can be very complete.......This paper continues the study of ETOL forms and good EOL forms done by Maurer, Salomaa and Wood. It is proven that binary very complete ETOL forms exist, good synchronized ETOL forms exist and that no propagating or synchronized ETOL form can be very complete....

  3. Transmission electron microscopy and EDS analysis of screen-printed contacts formation on multicrystalline silicon solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Thuillier, B.; Boyeaux, J.P.; Kaminski, A.; Laugier, A

    2003-09-15

    In photovoltaic industry, contacts fabrication is an important step for solar cell efficiency improvement. In order to reduce the cost of the device, the metallizations are realized by screen-printing a paste. In this work, we have analyzed large area industrial solar cells with pn{sup +} junction, SiO{sub 2} passivation layer and TiO{sub 2} antireflection coating (ARC) on front side. During the process, front contacts are screen-printed after TiO{sub 2} ARC deposition. The metallization paste is composed of a glass powder, an active metal (Ag for front paste and Ag/Al for rear paste) and a binding agent. Its deposition is followed by a rapid firing step at high temperature (firing through the oxide layers) and an annealing at lower temperature under reducing ambient. The aim of this study is to understand chemical and metallurgical mechanisms that occur in front and backside metallizations during heat treatments necessary for contacts formation. Cross-section samples are realized by the tripod method. Observations are realized with a 200 kV field effect gun-transmission electron microscope (TEM) associated to an EDS analysis. A software allows to pilot the beam, scanning along a surface or a line to obtain, respectively, an X-ray cartography or concentration profiles by elements. The main result of this analysis is that front contact ohmicity is not realized by the silver active metal of the paste but by metallic species coming from glass oxides.

  4. Milling Of Shaped Grooves - Profile Of Form Tools

    Science.gov (United States)

    Pilc, Jozef; Sajgalik, Michal; Stancekova, Dana; Janota, Miroslav; Pitela, David

    2015-12-01

    This paper deals with design of milling tool for milling of shaped groove. Actual industry production requires the large amount of tools and notably the special tools used for example when shaped milling. The requirements on the quality of tools are increasingly demanding. The quality of tools is given by construction, production process, selected material and also heat treatment. Shaped milling requires special tools made for given shape. Main request on the construction of tool is making of shape of cutting edge, which can produce the required shape of workpiece.

  5. MicroRNA expression profiling during upland cotton gland forming ...

    African Journals Online (AJOL)

    Abstract. Plant microRNAs (miRNAs) have important impacts on growth, development, flowering, metabolism and response to stress. ... This data may be useful in future studies associated with gland control involved in the terpenoid aldehyde biosynthesis pathway, genetic engineering and molecular breeding of cotton.

  6. A Patient with Splenic Artery Aneurysm Rupture and the Importance of Rapid Sonography in the ED

    Directory of Open Access Journals (Sweden)

    Masayuki Iyanaga

    2010-01-01

    Full Text Available We report a case of a splenic artery aneurysm rupture presenting with shock which required timely embolization therapy. This case demonstrates how the rapid use of bedside ultrasound by emergency department (ED physicians can help identify the cause of shock and, therefore, initiate appropriate treatment quickly even if the cause is rare, as in this case.

  7. Energy dispersive X-ray fluorescent (ED XRF) analyzer X-Art for investigation of artworks

    Science.gov (United States)

    Serebryakov, A. S.; Demchenko, E. L.; Koudryashov, V. I.; Sokolov, A. D.

    2004-01-01

    A novel compact ED XRF analyzer based on Si(Li) detector is developed for the attribution of artworks. Approbation of the instrument in two leading museums in Moscow and St. Petersburg showed that the chemical elements in the range from Mg to Pb can be determined in the artworks simultaneosely in the open air.

  8. Massively Open Online Course for Educators (MOOC-Ed) Network Dataset

    Science.gov (United States)

    Kellogg, Shaun; Edelmann, Achim

    2015-01-01

    This paper presents the Massively Open Online Course for Educators (MOOC-Ed) network dataset. It entails information on two online communication networks resulting from two consecutive offerings of the MOOC called "The Digital Learning Transition in K-12 Schools" in spring and fall 2013. The courses were offered to educators from the USA…

  9. ReEDS-Mexico: A Capacity Expansion Model of the Mexican Power System

    Energy Technology Data Exchange (ETDEWEB)

    Ho, Jonathan L [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Cole, Wesley J [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Spyrou, Evangelia [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-09-29

    This report documents the ReEDS-Mexico capacity expansion model, which is an extension of the ReEDS model to the Mexican power system. In recent years Mexico’s power sector has undergone considerable reform that has significant potential to impact the future electricity mix (Alpizar–Castro and Rodríguez–Monroy 2016). Day-ahead and real-time trading in Mexico’s power markets opened in early 2016. In addition to this reform, Mexico is striving to ensure that 35% of its electricity is generated from clean energy sources by 2024, 40% by 2035, and 50% by 2050 (Presidencia de la República 2016). These rapid changes in both the market and the generation mix create a need for robust tools that can help electricity sector stakeholders make informed decisions. The purpose of this report is to document the extension of the National Renewable Energy Laboratory’s (NREL’s) Regional Energy Deployment System (ReEDS) model (Eurek et al. 2016) to cover the Mexico power system. This extension, which we will refer to throughout this paper as ReEDS-Mexico, provides a model of the Mexico power sector using a system-wide, least-cost optimization framework.

  10. From fruit flies to fallout: Ed Lewis and his science1

    Indian Academy of Sciences (India)

    Administrator

    during the Depression, his father somehow managed to come up with funds to buy Ed a silver flute. He played in the High School Orchestra and the Wilkes-. Barre Symphony, beginning his tertiary education at. Bucknell College on a music scholarship. Howard D. Lipshitz. Journal of Genetics, Vol. 83, No. 2, August 2004 ...

  11. Developing a Culture of Learning around the edTPA: One University's Journey

    Science.gov (United States)

    Miller, Matthew; Carroll, David; Jancic, Mitchell; Markworth, Kimberly

    2015-01-01

    In this article, we discuss how an interdisciplinary faculty team at a midsized public university created supports for the Teacher Performance Assessment (edTPA), a high-stakes performance assessment for preservice candidates being adopted by many states. We provide a general description of our work in contending with the challenge of developing a…

  12. Global variables and identified hadrons in the PHENIX experiment

    Indian Academy of Sciences (India)

    PHENIX measurements related to global variables and identified hadrons are discussed. These include two-pion correlations, elliptic flow, and dN=dη. Measurements of event-by-event fluctuations in mean transverse momentum, mean transverse energy, and net charge are presented for particles within the PHENIX ...

  13. Problemi di fisica meccanica e termologia, ottica ed elettricità

    CERN Document Server

    Foglia, C

    1962-01-01

    Equazioni dimensionali ed unità di misura ; elementi di calcolo vettoriale ; cinematica ; dinamica ; fenomeni ondulatori ; meccanica dei fluidi ; termologia ; elettrostatica ; la corrente elettrica nei conduttori ohmici e non ohmici ; elettromagnetismo e correnti alternate ; equazioni di Maxwell e onde elettromagntiche ; ottica geometrica ; interferenza e diffrazione della luce ; polarizzazione della luce ; applicazioni elementari della teoria degli errori.

  14. APA Reporting Standards in Quantitative Research Dissertations from an Online EdD Program

    Science.gov (United States)

    Salgado, Griselle

    2013-01-01

    This study was an investigation of the reporting practices in dissertations with quantitative research designs produced by students enrolled in an online Doctor of Education (EdD) program, one that follows the American Psychological Association (APA) standards for reporting research. Limited, empirical information exists about the competencies in…

  15. (M.Ed.) students' experiences of part-time study: A South African

    African Journals Online (AJOL)

    This article reports on a study of how a group of first year M.Ed. students in the Faculty of Education of the University of KwaZulu-Natal experienced part-time study. Literature suggests that each year, South Africa suffers significant student departures from universities without completing their studies. Apart from the cost and ...

  16. J. Crush and D.A. McDonald. (eds). 2002. Transnationalism and ...

    African Journals Online (AJOL)

    J. Crush and D.A. McDonald. (eds). 2002. Transnationalism and New African Immigration to South Africa. Cape Town. Southern African Migration Project and the Canadian Association of African Studies. IV + 188 pp. ISBN 0-88911-926-0.

  17. A Comparative SEM-EDS Elemental Composition of Mud in Coastal ...

    African Journals Online (AJOL)

    The present study was aimed to understand the comparative abundance and source of elemental constituents in mud of four coastal shrimp farming areas, Vunh Tau (VT), Nha Trang (NT), Da Nang (DN) and Hue (HU) in Viet Nam using SEM-EDS analysis. Mud samples were collected from shrimp farming coastal zones ...

  18. 09 | 26 | organic.html 3 | chemistry | resources | sci ed | initiat | Indian ...

    Indian Academy of Sciences (India)

    Home; initiat; sci ed; resources; chemistry; organic.html 3; 26; 09. 404! error. The page your are looking for can not be found! Please check the link or use the navigation bar at the top. YouTube · Twitter · Facebook · Blog. Academy News. IAS Logo. Good Governance: Contribution of Vigilance · Vigilance Awareness Talk

  19. WORK-ED. (World of Related Knowledge and Educational Development). A Manual for Trainers.

    Science.gov (United States)

    Fraleigh, Virginia A.

    This manual is designed to assist personnel responsible for training teachers in the implementation of the World of Related Knowledge and Educational Development (WORK-ED). (The program is a career education course for ninth graders developed to enable students who have not chosen the traditional college-prep high school course to make career…

  20. Work-Ed. A Guide to the Changing World of Work.

    Science.gov (United States)

    Fraleigh, Virginia A.

    A description of the project, its development process, evaluation results, and exportability are included in this overview of WORK-ED (World of Related Knowledge and Educational Development), a program to provide ninth grade students both basic skills in communication and exposure to twelve career clusters. Introductory sections describe the…

  1. Impact of Curricular Reforms on Educational Philosophy Courses in M.Ed Programmes

    Science.gov (United States)

    Gafoor, K. Abdul; Remia, K. R.

    2014-01-01

    In the context of Vision of Teacher Education envisaged in National Curriculum Framework for Teacher Education, this study probes "Do M.Ed programmes provide for the prerequisites of educational philosophy for teacher educators?" and "whether the syllabi following credit and non credit pattern vary in their coverage of content of…

  2. A bimodal tomographic reconstruction technique combining EDS-STEM and HAADF-STEM

    NARCIS (Netherlands)

    Z. Zhong (Zhichao); B. Goris (Bart); Schoenmakers, R. (Remco); S. Bals (Sara); K.J. Batenburg (Joost)

    2017-01-01

    textabstractA three-dimensional (3D) chemical characterization of nanomaterials can be obtained using tomography based on high angle annular dark field (HAADF) scanning transmission electron microscopy (STEM) or energy dispersive X-ray spectroscopy (EDS) STEM. These two complementary techniques have

  3. EFNEP and SNAP-Ed Initial Paraprofessional Training Materials and Methods

    Science.gov (United States)

    Byington, Charlene; Baker, Susan

    2012-01-01

    Western Region EFNEP coordinators were frustrated by the apparent lack of materials available for training newly hired paraprofessional nutrition educators. An on-line survey was distributed to all EFNEP and SNAP-Ed state coordinators seeking details about initial training and available materials and requesting copies of materials for review.…

  4. An Analysis of Professional Practice Ed.D. Dissertations in Educational Technology

    Science.gov (United States)

    Dawson, Kara; Kumar, Swapna

    2014-01-01

    The University of Florida offers an online professional practice Ed.D. focused on Educational Technology. Twenty-three students have completed professional practice dissertations and graduated since the program's inception in 2008. The purpose of this article is to share what these dissertations have looked like and to begin a dialogue about…

  5. Syncope prevalence in the ED compared to general practice and population: a strong selection process

    NARCIS (Netherlands)

    Olde Nordkamp, Louise R. A.; van Dijk, Nynke; Ganzeboom, Karin S.; Reitsma, Johannes B.; Luitse, Jan S. K.; Dekker, Lukas R. C.; Shen, Win-Kuang; Wieling, Wouter

    2009-01-01

    Objective: We assessed the prevalence and distribution of the different causes of transient loss of consciousness (TLOC) in the emergency department (ED) and chest pain unit (CPU) and estimated the proportion of persons with syncope in the general population who seek medical attention from either

  6. Communicative Learning Outcomes and World Language edTPA: Characteristics of High-Scoring Portfolios

    Science.gov (United States)

    Swanson, Pete; Hildebrandt, Susan A.

    2017-01-01

    Teacher accountability continues to be at the forefront of educational policy in the United States, with the current focus on the Outcomes of K-12 teaching and teacher education (Cochran-Smith 2000). edTPA, a high-stakes assessment used in many states to make licensure or certification decisions, purports to measure those content-specific…

  7. Introducing the Collaborative E-Learning Design Method (CoED)

    DEFF Research Database (Denmark)

    Ryberg, Thomas; Buus, Lillian; Nyvang, Tom

    2015-01-01

    In this chapter, a specific learning design method is introduced and explained, namely the Collaborative E-learning Design method (CoED), which has been developed through various projects in “e-Learning Lab – Centre for User Driven Innovation, Learning and Design” (Nyvang & Georgsen, 2007). We br...

  8. Book review: Robert Leckey (ed. After Legal Equality: Family, Sex, Kinship

    Directory of Open Access Journals (Sweden)

    Pawel Drągowski

    2015-12-01

    Full Text Available Book review: Robert Leckey (ed. After Legal Equality: Family, Sex, Kinship. Abingdon: Oxon; New York, NY: Routledge, 2015, pp. 224, ISBN 978-0-415-72161-5 £85DOWNLOAD THIS PAPER FROM SSRN: http://ssrn.com/abstract=2707055

  9. Children's Productions of the Affix -"ed" in Past Tense and Past Participle Contexts

    Science.gov (United States)

    Redmond, Sean M.

    2003-01-01

    Children's productions of the affix -"ed" in past tense and past participle contexts (e.g., "the boy kicked the ball" vs. "the ball was kicked") were examined in spontaneous conversations and elicited productions. The performances of 7 children with specific language impairment (SLI) were compared with those of 2 control groups of typically…

  10. Identified hadron production in $\\sqrt {s}= 130$ GeV Au–Au ...

    Indian Academy of Sciences (India)

    ... Pramana – Journal of Physics; Volume 60; Issue 5. Identified hadron production in s = 130 GeV Au–Au collisions at relativistic heavy-ion collider. Julia Velkovska. Volume 60 Issue 5 May 2003 pp 1011-1015 ... Author Affiliations. Julia Velkovska1. Brookhaven National Laboratory, Bldg. 510C, Upton, NY 11973, USA ...

  11. Unique program aims to connect frequent ED utilizers with medical homes, resources to meet complex needs.

    Science.gov (United States)

    2014-10-01

    Sinai Hospital of Baltimore in Baltimore, MD, is partnering with HealthCare Access Maryland, a non-profit organization in the state, to link patients who frequent the ED for care with medical homes and other resources that can better meet their medical and social needs. Under the Access Health Program, ED-based care coordinators intervene with patients who meet program criteria, linking them with medical homes and other resources that address their complex needs. The hospital has devised a flag to notify the ED when a frequent-utilizing patient presents in the department for care. Care coordinators then meet with these patients and get their consent to participate in the program. Within a week of the ED visit, care coordinators schedule a home visit with the patient to establish a care plan containing specific goals and a time frame to carry out these goals. Patients remain in the program for 90 days as care coordinators work to hand them off to longer-term resources. Many of the patients enrolled in the program have substance abuse and mental health problems. Patients are also often uninsured and/or homeless. Within two months of launching the program, care coordinators enrolled 74 patients, with the goal of eventually bringing that number to 200.

  12. Viirastuslikud Sinimäed. Mõtteid Raimo Jõeranna filmi ainetel / Rein Ruutsoo

    Index Scriptorium Estoniae

    Ruutsoo, Rein, 1947-

    2006-01-01

    6-osalise ajaloodokumentaalide sarja "Kuum külm sõda" teist filmi "Sinimäed" : stsenaristid Kiur Aarma, Mart Laar, Eerik-Niiles Kross, Raimo Jõerand : režissöör Raimo Jõerand : Ruut Pictures 2006

  13. MobilED: a mobile tools and services platform for formal and informal learning

    CSIR Research Space (South Africa)

    Ford, M

    2009-03-01

    Full Text Available MobilED is a South African initiative aimed at designing teaching and learning environments that are meaningfully enhanced with mobile technologies and services. The deliverables are the development of a set of scenarios and guidelines on how mobile...

  14. Cross-sectional analysis of fouled SWRO membranes by STEM-EDS

    KAUST Repository

    Aubry, Cyril

    2014-01-01

    The intact cross-section of two fouled reverse osmosis membranes was characterized using a scanning transmission electron microscope (STEM) equipped with an electron energy dispersive spectroscope (EDS). Focused ion beam (FIB) was used to prepare a thin lamella of each membrane. These lamellas were then attached to a TEM grid for further STEM/EDS analysis. The foulant in sample A was mainly inorganic in nature and predominantly composed of alumino-silicate particles. These particles were surrounded by carbon at high concentrations, indicating the presence of organic materials. Iron was diffusely present in the cake layer and this could have enhanced the fouling process. The cake layer of membrane B was mainly consisted of organic matter (C, O, and N representing 95% of the total elemental composition) and organized in thin parallel layers. Small concentrations of Si, F, Na, Mg, and Cl were detected inside the active layer and support layer of the membrane. Due to the high sensitivity of the cake layer of membrane A to the electron beam, STEM/EDS line analyses might have been performed on large areas. On the other hand, the cake layer of sample B was resistant to the electron beam and the resolution of STEM/EDS was gradually improved until obtaining a resolution of 25. nm. © 2013 Elsevier B.V.

  15. The use of open source electronic medical records in an urban ED in Kumasi-Ghana

    Directory of Open Access Journals (Sweden)

    P.K. Forson*

    2013-12-01

    Conclusion: Open source medical records may be the most appropriate and cost-effective software to adapt for keeping patient records electronically in a low resource setting. Further studies need to be conducted to demonstrate how EMR may affect the pace of work in the ED.

  16. The role of plain radiographs in patients with acute abdominal pain at the ED

    NARCIS (Netherlands)

    Randen, A. van; Lameris, W.; Luitse, J.S.; Gorzeman, M.; Hesselink, E.J.; Dolmans, D.E.; Peringa, J.; Geloven, A.A. van; Bossuyt, P.M.; Stoker, J.; Boermeester, M.A.; Gooszen, H.G.

    2011-01-01

    OBJECTIVE: The purpose of this study was to evaluate the added value of plain radiographs on top of clinical assessment in unselected patients presenting with acute abdominal pain at the emergency department (ED). METHODS: In a multicenter prospective trial, patients with abdominal pain more than 2

  17. The role of plain radiographs in patients with acute abdominal pain at the ED

    NARCIS (Netherlands)

    van Randen, Adrienne; Lameris, Wytze; Luitse, Jan S. K.; Gorzeman, Michiel; Hesselink, Erik J.; Dolmans, Dennis E. J. G. J.; Peringa, Jan; van Geloven, Anna A. W.; Bossuyt, Patrick M.; Stoker, Jaap; Boermeester, Marja A.

    Objective: The purpose of this study was to evaluate the added value of plain radiographs on top of clinical assessment in unselected patients presenting with acute abdominal pain at the emergency department (ED). Methods: In a multicenter prospective trial, patients with abdominal pain more than 2

  18. Systematic Review of ED-based Intimate Partner Violence Intervention Research

    Directory of Open Access Journals (Sweden)

    Esther K. Choo,

    2015-12-01

    Full Text Available Introduction: Assessment reactivity may be a factor in the modest results of brief interventions for substance use in the emergency department (ED. The presence of assessment reactivity in studies of interventions for intimate partner violence (IPV has not been studied. Our objectives were to identify ED IPV intervention studies and evaluate the presence of a consistently positive effect on the control groups. Methods: We performed a systematic search of electronic databases for English=language intervention studies addressing IPV in the ED published since 1990. Study selection and assessment of methodologic quality were performed by two independent reviewers. Data extraction was performed by one reviewer and then independently checked for completeness and accuracy by a second reviewer. Results: Of 3,620 unique manuscripts identified by database search, 667 underwent abstract review and 12 underwent full-text review. Only three met full eligibility criteria; data on the control arm were available for two studies. In these two studies, IPV-related outcomes improved for both the experimental and control condition. Conclusion: The paucity of controlled trials of IPV precluded a robust evaluation for assessment reactivity. This study highlighted a critical gap in ED research on IPV.

  19. Next Generation Science Standards and edTPA: Evidence of Science and Engineering Practices

    Science.gov (United States)

    Brownstein, Erica M.; Horvath, Larry

    2016-01-01

    Science teacher educators in the United States are currently preparing future science teachers to effectively implement the "Next Generation Science Standards" (NGSS) and, in thirteen states, to successfully pass a content-specific high stakes teacher performance assessment, the edTPA. Science education and teacher performance assessment…

  20. Using Ontological Engineering to Overcome AI-ED Problems: Contribution, Impact and Perspectives

    Science.gov (United States)

    Mizoguchi, Riichiro; Bourdeau, Jacqueline

    2016-01-01

    This article reflects on the ontology engineering methodology discussed by the paper entitled "Using Ontological Engineering to Overcome AI-ED Problems" published in this journal in 2000. We discuss the achievements obtained in the last 10 years, the impact of our work as well as recent trends and perspectives in ontology engineering for…

  1. Tackling causes and costs of ED presentation for American football injuries: a population-level study.

    Science.gov (United States)

    Smart, Blair J; Haring, R Sterling; Asemota, Anthony O; Scott, John W; Canner, Joseph K; Nejim, Besma J; George, Benjamin P; Alsulaim, Hatim; Kirsch, Thomas D; Schneider, Eric B

    2016-07-01

    American tackle football is the most popular high-energy impact sport in the United States, with approximately 9 million participants competing annually. Previous epidemiologic studies of football-related injuries have generally focused on specific geographic areas or pediatric age groups. Our study sought to examine patient characteristics and outcomes, including hospital charges, among athletes presenting for emergency department (ED) treatment of football-related injury across all age groups in a large nationally representative data set. Patients presenting for ED treatment of injuries sustained playing American tackle football (identified using International Classification of Diseases, Ninth Revision, Clinical Modification code E007.0) from 2010 to 2011 were studied in the Nationwide Emergency Department Sample. Patient-specific injuries were identified using the primary International Classification of Diseases, Ninth Revision, Clinical Modification diagnosis code and categorized by type and anatomical region. Standard descriptive methods examined patient demographics, diagnosis categories, and ED and inpatient outcomes and charges. During the study period 397363 football players presented for ED treatment, 95.8% of whom were male. Sprains/strains (25.6%), limb fractures (20.7%), and head injuries (including traumatic brain injury; 17.5%) represented the most presenting injuries. Overall, 97.9% of patients underwent routine ED discharge with 1.1% admitted directly and fewer than 11 patients in the 2-year study period dying prior to discharge. The proportion of admitted patients who required surgical interventions was 15.7%, of which 89.9% were orthopedic, 4.7% neurologic, and 2.6% abdominal. Among individuals admitted to inpatient care, mean hospital length of stay was 2.4days (95% confidence interval, 2.2-2.6) and 95.6% underwent routine discharge home. The mean total charge for all patients was $1941 (95% confidence interval, $1890-$1992) with substantial

  2. Progress of the BT-EdF-CEA project. The lithium polymer battery; Avancees du projet BT-EdF-CEA. Batterie lithium polymere

    Energy Technology Data Exchange (ETDEWEB)

    Marginedes, D.; Majastre, H. [Bollore Technologies, 29 - Quimper (France); Baudry, P.; Lascaud, S. [Electricite de France, 77 - Moret sur Loing (France). Direction des Etudes et Recherches; Bloch, D.; Lebrun, N. [CEA Grenoble, CEREM, 38 (France)

    1996-12-31

    The lithium-polymer energy storage technology requires the production of thin films of huge surface. The BT-EdF-CEA consortium has studied the various manufacturing techniques of these films and their assembly. The process was chosen according to its productivity, low expensiveness, ecological impact and energy performances with capacities reaching 40 Ah. This paper explains: the objectives and specifications of the project, the advantage of the consortium and the role of the different partners, the results (coating, dry extrusion and battery element manufacturing techniques), and the electrochemical performances of the elements. (J.S.)

  3. relline: Relativistic line profiles calculation

    Science.gov (United States)

    Dauser, Thomas

    2015-05-01

    relline calculates relativistic line profiles; it is compatible with the common X-ray data analysis software XSPEC (ascl:9910.005) and ISIS (ascl:1302.002). The two basic forms are an additive line model (RELLINE) and a convolution model to calculate relativistic smearing (RELCONV).

  4. Soil Profiles and Seismic Loading

    Directory of Open Access Journals (Sweden)

    Janotka, V.

    2006-01-01

    Full Text Available The contribution estimates different geotechnical profiles of site condition change and their influences on the computed seismic response spectra and time histories final values and forms applying on the seismic structures loading. The mentioned problems methodics attitude solution is based on the computed seismic motion parameters.

  5. English Language Teaching Profile: Cyprus.

    Science.gov (United States)

    British Council, London (England). English-Teaching Information Centre.

    This profile in outline form of the English language teaching situation in Cyprus discusses the role of English within the Greek Cypriot community and within the educational system. Areas covered include English language requirements and English within the curriculum, teaching personnel and teacher training, instructional materials, English…

  6. Is scanning electron microscopy/energy dispersive X-ray spectrometry (SEM/EDS) quantitative?

    Science.gov (United States)

    Newbury, Dale E; Ritchie, Nicholas W M

    2013-01-01

    Scanning electron microscopy/energy dispersive X-ray spectrometry (SEM/EDS) is a widely applied elemental microanalysis method capable of identifying and quantifying all elements in the periodic table except H, He, and Li. By following the "k-ratio" (unknown/standard) measurement protocol development for electron-excited wavelength dispersive spectrometry (WDS), SEM/EDS can achieve accuracy and precision equivalent to WDS and at substantially lower electron dose, even when severe X-ray peak overlaps occur, provided sufficient counts are recorded. Achieving this level of performance is now much more practical with the advent of the high-throughput silicon drift detector energy dispersive X-ray spectrometer (SDD-EDS). However, three measurement issues continue to diminish the impact of SEM/EDS: (1) In the qualitative analysis (i.e., element identification) that must precede quantitative analysis, at least some current and many legacy software systems are vulnerable to occasional misidentification of major constituent peaks, with the frequency of misidentifications rising significantly for minor and trace constituents. (2) The use of standardless analysis, which is subject to much broader systematic errors, leads to quantitative results that, while useful, do not have sufficient accuracy to solve critical problems, e.g. determining the formula of a compound. (3) EDS spectrometers have such a large volume of acceptance that apparently credible spectra can be obtained from specimens with complex topography that introduce uncontrolled geometric factors that modify X-ray generation and propagation, resulting in very large systematic errors, often a factor of ten or more. © Wiley Periodicals, Inc.

  7. The Phosphodiesterase 5-Inhibitors (PDE-5i) for ERECTILE DYSFUNCTION (ED): A Therapeutic Challenge For Psychiatrists.

    Science.gov (United States)

    Koon, Chong Siew; Sidi, Hatta; Kumar, Jaya; Das, Srijit; Xi, Ong Wan; Hatta, Muhammad Hizri; Alfonso, Cesar

    2017-02-15

    Erectile function (EF) is a prerequisite for satisfactory sexual intercourse (SI) and central to male sexual functioning. Satisfactory SI eventually leads to orgasm - a biopsychophysiological state of euphoria - leading to a sense of bliss, enjoyment and positive mental well being. For a psychiatrist, treating ED is self-propelled to harmonize these pleasurable experiences alongside with encouragement of physical wellness and sensuality. Hence, the role of PDE-5i is pivotal in the context of treating ED constitutes a therapeutic challenge. PDE-5i work via the dopaminergic-oxytocin-nitric oxide pathway by increasing the availability of endothelial's guanosine monophosphate (GMP), immediately causing relaxation of the penile smooth muscle and an erection. The PDE-5i, like sildenafil, vardenafil and tadalafil, are effective in the treatment of ED with some benefits and disadvantages compared to other treatment modalities. Prescribed PDE-5i exclusively improve EF, fostering male's self-confidence and self-esteem. Treatment failures are associated with factors such as absent (or insufficient) sexual stimulation, psychosexual conflicts and the co-existence of medical disorders. Managing ED requires dealing with underlying medical diseases, addressing other co-morbid sexual dysfunctions like premature ejaculation (PE), and educating the patient on healthy life-styles beside being cautious with the potential side-effects and drug-drug interactions. Furthermore, by dealing with interpersonal dynamics within the couple and embracing adequate lifestyles (managing stress and revising one's sexual scripts), PDE-5i treatment benefits may be enhanced. In this review, we propose a holistic conceptual framework approach for psychiatric management of patients with ED. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  8. Ed Couzens

    African Journals Online (AJOL)

    MJM Venter

    users – human beings, for a daily needs component, and the environment itself – became the only "priority ... Stewart and Horsten argue that "South Africa is one of the few jurisdictions in the world that provides for an ... ruling on payment for water services in Mazibuko, questions related to access to water will continue to ...

  9. Estimation of the release profiles of multi-unit dose tablets of theophylline from the release profiles of their components

    National Research Council Canada - National Science Library

    Uhumwangho, M.U; Okor, R.S

    2008-01-01

    Purpose: The objective of this study is to investigate whether the drug release profile of a multi-unit dose form consisting of fast and slow release components can be predicted from the release profiles...

  10. SEM/EDS analysis of soil and roasting vessels fragments from ancient mercury ore roasting sites at Idrija area

    Directory of Open Access Journals (Sweden)

    Tamara Teršič

    2011-06-01

    Full Text Available Numerous roasting vessels fragments can be found at ancient roasting site areas in the surroundings of Idrija town, which were used for ore roasting in the first 150 years of Hg production in Idrija. The earthen vessels fragments lay just below the surface humus layer and in some parts they stretch more than 1 meter deep; they arecovered with red (cinnabar or black (metacinnabar coatings.SEM/EDS analysis of roasting vessels fragments and soil samples from roasting site areas P{enk and Frbejžene trate was performed in order to characterize the solid forms of Hg in applied sampling material. Mercuric sulphide HgS was found to be the main mercury compound present in the samples. Analysis of earthen vessels fragmentsshowed abundant HgS coatings on the surface of ceramics, forming either crust-like aggregates on matrix or isolated grains. Some well-shaped grains with indicated structure and the size of up to 200 μm could also be observed. In soil HgS was present as powder-like concentrations scattered in soil samples, frequently coating silicate and quartz crystals and clay-minerals. Polycristalline, mercury- and sulphur- rich particles comprising silica, clay mineralsand Al-, Fe- and Mg-oxides that were also observed in the samples were interpreted as soil aggregates infiltrated by mercuric and sulphur vapours and by liquid mercury spilled during roasting. These particles suggest a possible presence of mercury-sulphur associations other than HgS.

  11. Modular Forms and Weierstrass Mock Modular Forms

    Directory of Open Access Journals (Sweden)

    Amanda Clemm

    2016-02-01

    Full Text Available Alfes, Griffin, Ono, and Rolen have shown that the harmonic Maass forms arising from Weierstrass ζ-functions associated to modular elliptic curves “encode” the vanishing and nonvanishing for central values and derivatives of twisted Hasse-Weil L-functions for elliptic curves. Previously, Martin and Ono proved that there are exactly five weight 2 newforms with complex multiplication that are eta-quotients. In this paper, we construct a canonical harmonic Maass form for these five curves with complex multiplication. The holomorphic part of this harmonic Maass form arises from the Weierstrass ζ-function and is referred to as the Weierstrass mock modular form. We prove that the Weierstrass mock modular form for these five curves is itself an eta-quotient or a twist of one. Using this construction, we also obtain p-adic formulas for the corresponding weight 2 newform using Atkin’s U-operator.

  12. On the importance of personal profiles to enhance social interaction in Learning Networks

    NARCIS (Netherlands)

    Berlanga, Adriana; Bitter-Rijpkema, Marlies; Brouns, Francis; Sloep, Peter

    2008-01-01

    Berlanga, A. J., Bitter-Rijpkema, M., Brouns F., & Sloep, P.B. (2008). On the importance of personal profiles to enhance social interaction in Learning Networks. In P. Kommers (Ed.), Proceedings of Web Based Communities Conference (WEBC 2008) (pp. 55-62). July, 24-26, 2008, Amsterdam, The

  13. Collis-Romberg Mathematical Problem Solving Profiles.

    Science.gov (United States)

    Collis, K. F.; Romberg, T. A.

    Problem solving has become a focus of mathematics programs in Australia in recent years, necessitating the assessment of students' problem-solving abilities. This manual provides a problem-solving assessment and teaching resource package containing four elements: (1) profiles assessment items; (2) profiles diagnostic forms for recording individual…

  14. 48 CFR 3432.770 - Prohibition against the use of ED funds to influence legislation or appropriations.

    Science.gov (United States)

    2010-10-01

    ... use of ED funds to influence legislation or appropriations. 3432.770 Section 3432.770 Federal... legislation or appropriations. The contracting officer shall insert the clause at 3452.232-70, Prohibition Against the Use of ED Funds to Influence Legislation or Appropriations, in contracts with educational...

  15. 48 CFR 3452.232-70 - Prohibition against the use of ED funds to influence legislation or appropriations.

    Science.gov (United States)

    2010-10-01

    ... use of ED funds to influence legislation or appropriations. 3452.232-70 Section 3452.232-70 Federal... funds to influence legislation or appropriations. The following clause is to be used in accordance with 3432.770: Prohibition Against the Use of ED Funds To Influence Legislation or Appropriations (APR 1987...

  16. Disruption of the Arabidopsis Defense Regulator Genes SAG101, EDS1, and PAD4 Confers Enhanced Freezing Tolerance.

    Science.gov (United States)

    Chen, Qin-Fang; Xu, Le; Tan, Wei-Juan; Chen, Liang; Qi, Hua; Xie, Li-Juan; Chen, Mo-Xian; Liu, Bin-Yi; Yu, Lu-Jun; Yao, Nan; Zhang, Jian-Hua; Shu, Wensheng; Xiao, Shi

    2015-10-05

    In Arabidopsis, three lipase-like regulators, SAG101, EDS1, and PAD4, act downstream of resistance protein-associated defense signaling. Although the roles of SAG101, EDS1, and PAD4 in biotic stress have been extensively studied, little is known about their functions in plant responses to abiotic stresses. Here, we show that SAG101, EDS1, and PAD4 are involved in the regulation of freezing tolerance in Arabidopsis. With or without cold acclimation, the sag101, eds1, and pad4 single mutants, as well as their double mutants, exhibited similarly enhanced tolerance to freezing temperatures. Upon cold exposure, the sag101, eds1, and pad4 mutants showed increased transcript levels of C-REPEAT/DRE BINDING FACTORs and their regulons compared with the wild type. Moreover, freezing-induced cell death and accumulation of hydrogen peroxide were ameliorated in sag101, eds1, and pad4 mutants. The sag101, eds1, and pad4 mutants had much lower salicylic acid (SA) and diacylglycerol (DAG) contents than the wild type, and exogenous application of SA and DAG compromised the freezing tolerance of the mutants. Furthermore, SA suppressed the cold-induced expression of DGATs and DGKs in the wild-type leaves. These findings indicate that SAG101, EDS1, and PAD4 are involved in the freezing response in Arabidopsis, at least in part, by modulating the homeostasis of SA and DAG. Copyright © 2015 The Author. Published by Elsevier Inc. All rights reserved.

  17. Communication and Influencing for ED Professionals: A training programme developed in the emergency department for the emergency department.

    Science.gov (United States)

    Rixon, Andrew; Rixon, Sascha; Addae-Bosomprah, Hansel; Ding, Mingshuang; Bell, Anthony

    2016-08-01

    The objective of the present study is to develop and pilot a communication and influencing skills training programme that meets ED health professionals' needs at an urban district hospital. Qualitative methods within a participatory action research framework were utilised. An interdisciplinary team guided the programme's design and development. A training needs analysis saw team meetings, interviews, focus groups and observations conducted across the ED. Thematic analysis of the data identified health professionals' communication and influencing challenges. The training needs analysis informed the training programme curriculum's development. The pilot programme involved an interdisciplinary group of seven health professionals across 5 × 2 h sessions over 3 months, followed by a post-training survey. Five themes of communication and influencing challenges were identified: participating in effective handovers, involving patients in bedside handovers, effectively communicating with interdepartmental colleagues, asking ED colleagues to do tasks and understanding ED colleagues' roles, expectations and assumptions. Based on these challenges, the formulated RESPECT model (which stands for Relationships, Expectations, Styles, Partnerships, Enquiry, Coaching and Teamwork) informed the training curriculum. The peer coaching model used in the training programme was highly regarded by participants. Communication and Influencing for ED Professionals™ (Babel Fish Group Pty Ltd, Melbourne, Victoria, Australia) addresses a gap for communication programmes developed in the ED for the ED. Future research will evaluate the programme's impact in this ED. © 2016 Australasian College for Emergency Medicine and Australasian Society for Emergency Medicine.

  18. A numerical analysis on forming limits during spiral and concentric single point incremental forming

    Science.gov (United States)

    Gipiela, M. L.; Amauri, V.; Nikhare, C.; Marcondes, P. V. P.

    2017-01-01

    Sheet metal forming is one of the major manufacturing industries, which are building numerous parts for aerospace, automotive and medical industry. Due to the high demand in vehicle industry and environmental regulations on less fuel consumption on other hand, researchers are innovating new methods to build these parts with energy efficient sheet metal forming process instead of conventionally used punch and die to form the parts to achieve the lightweight parts. One of the most recognized manufacturing process in this category is Single Point Incremental Forming (SPIF). SPIF is the die-less sheet metal forming process in which the single point tool incrementally forces any single point of sheet metal at any process time to plastic deformation zone. In the present work, finite element method (FEM) is applied to analyze the forming limits of high strength low alloy steel formed by single point incremental forming (SPIF) by spiral and concentric tool path. SPIF numerical simulations were model with 24 and 29 mm cup depth, and the results were compare with Nakajima results obtained by experiments and FEM. It was found that the cup formed with Nakajima tool failed at 24 mm while cups formed by SPIF surpassed the limit for both depths with both profiles. It was also notice that the strain achieved in concentric profile are lower than that in spiral profile.

  19. Higher Ed Meets Public Ed.

    Science.gov (United States)

    Olenick, Mary Jo

    1996-01-01

    The University of Connecticut is revitalizing the Avery Point campus with two new buildings. A Marine Sciences and Technology Center will serve graduate and undergraduate students. A separate Marine Sciences Field Station/Hostel will house Project Oceanology: a science program for students in grades 5-12. (MLF)

  20. [Profile rhinoplasty].

    Science.gov (United States)

    Mühlbauer, W

    1986-03-01

    Profileplasty is an extension of rhinoplasty. It encompasses the minimal correction of the shape of the nose, correction of the upper and lower jaws, remodelling the contour of the neck as well as the reshaping of the entire neuro- and viscerocranium applying the techniques of craniofacial surgery. While the patient sets the indication, the surgeon acts as a consultant. Beside technical skills in performing a profileplasty, a good sense for harmonious proportions is more important than exact measurements. Rhino- and profileplasty come close to one of the essential goals of plastic surgery. Form, function and appearance of a person may be altered to his advantage without visible scars. Better appearance usually initiates a positive development of the personality.

  1. Using Google Flu Trends data in forecasting influenza-like-illness related ED visits in Omaha, Nebraska.

    Science.gov (United States)

    Araz, Ozgur M; Bentley, Dan; Muelleman, Robert L

    2014-09-01

    Emergency department (ED) visits increase during the influenza seasons. It is essential to identify statistically significant correlates in order to develop an accurate forecasting model for ED visits. Forecasting influenza-like-illness (ILI)-related ED visits can significantly help in developing robust resource management strategies at the EDs. We first performed correlation analyses to understand temporal correlations between several predictors of ILI-related ED visits. We used the data available for Douglas County, the biggest county in Nebraska, for Omaha, the biggest city in the state, and for a major hospital in Omaha. The data set included total and positive influenza test results from the hospital (ie, Antigen rapid (Ag) and Respiratory Syncytial Virus Infection (RSV) tests); an Internet-based influenza surveillance system data, that is, Google Flu Trends, for both Nebraska and Omaha; total ED visits in Douglas County attributable to ILI; and ILI surveillance network data for Douglas County and Nebraska as the predictors and data for the hospital's ILI-related ED visits as the dependent variable. We used Seasonal Autoregressive Integrated Moving Average and Holt Winters methods with3 linear regression models to forecast ILI-related ED visits at the hospital and evaluated model performances by comparing the root means square errors (RMSEs). Because of strong positive correlations with ILI-related ED visits between 2008 and 2012, we validated the use of Google Flu Trends data as a predictor in an ED influenza surveillance tool. Of the 5 forecasting models we have tested, linear regression models performed significantly better when Google Flu Trends data were included as a predictor. Regression models including Google Flu Trends data as a predictor variable have lower RMSE, and the lowest is achieved when all other variables are also included in the model in our forecasting experiments for the first 5 weeks of 2013 (with RMSE = 57.61). Google Flu Trends data

  2. Experiences of patients with acute abdominal pain in the ED or acute surgical ward --a qualitative comparative study

    DEFF Research Database (Denmark)

    Schultz, Helen; Qvist, Niels; Backer Mogensen, Christian

    2013-01-01

    The Danish health care system is currently establishing emergency departments (EDs) with an observation unit nationwide. The aim of the study was to investigate patients with acute abdominal pain and their experiences upon arrival and stay in an acute surgical ward (ASW) versus an ED with an obse......The Danish health care system is currently establishing emergency departments (EDs) with an observation unit nationwide. The aim of the study was to investigate patients with acute abdominal pain and their experiences upon arrival and stay in an acute surgical ward (ASW) versus an ED...... was that the ED included a multidisciplinary team with nurses, who mainly had interactions with the patients before surgical assessment. In all, it resulted in fragmentation of care and a patient experience of repetition. In ASW, focus was on assessment by a senior physician, only, and the nurses' interaction...

  3. The NOURISHED randomised controlled trial comparing mentalisation-based treatment for eating disorders (MBT-ED) with specialist supportive clinical management (SSCM-ED) for patients with eating disorders and symptoms of borderline personality disorder.

    Science.gov (United States)

    Robinson, Paul; Hellier, Jennifer; Barrett, Barbara; Barzdaitiene, Daiva; Bateman, Anthony; Bogaardt, Alexandra; Clare, Ajay; Somers, Nadia; O'Callaghan, Aine; Goldsmith, Kimberley; Kern, Nikola; Schmidt, Ulrike; Morando, Sara; Ouellet-Courtois, Catherine; Roberts, Alice; Skårderud, Finn; Fonagy, Peter

    2016-11-17

    In this multi-centre randomized controlled trial (RCT) we compared modified mentalisation-based treatment (MBT-ED) to specialist supportive clinical management (SSCM-ED) in patients with eating disorders (EDs) and borderline personality disorder symptoms (BPD). This group of patients presents complex challenges to clinical services, and a treatment which addresses their multiple problems has the potential to improve outcome. MBT has been shown to be effective in improving outcome in patients with BPD, but its use has not been reported in ED. Sixty-eight eligible participants were randomised to MBT-ED or SSCM-ED. The primary outcome measure was the global score on the Eating Disorder Examination. Secondary outcomes included measures of BPD symptoms (the Zanarini Rating Scale for Borderline Personality Disorder), general psychiatric state, quality of life and service utilisation. Participants were assessed at baseline and at 6, 12 and 18 months after randomisation. Analysis was performed using linear mixed models. Only 15 participants (22 %) completed the 18 month follow-up. Early drop-out occurred significantly more in the SSCM-ED group. Drop-out did not vary with treatment model later in therapy and was sometimes attributed to participants moving away. There was higher drop--out amongst smokers and those with higher neuroticism scores. 47.1 % of participants in the MBT-ED arm and 37.1 % in the SSCM-ED arm attended at least 50 % of therapy sessions offered. Amongst those remaining in the trial, at 12 and 18 months MBT-ED was associated with a greater reduction in Shape Concern and Weight Concern in the Eating Disorder Examination compared to SSCM-ED. At 6, 12 and 18 months there was a decline of ED and BPD symptoms in both groups combined. Ten participants were reported as having had adverse events during the trial, mostly self-harm, and there was one death, attributed as 'unexplained' by the coroner. The high drop-out rate made interpretation of the results

  4. Manufacturing processes 4 forming

    CERN Document Server

    Klocke, Fritz

    2013-01-01

    This book provides essential information on metal forming, utilizing a practical distinction between bulk and sheet metal forming. In the field of bulk forming, it examines processes of cold, warm and hot bulk forming, as well as rolling and a new addition, the process of thixoforming. As for the field of sheet metal working, on the one hand it deals with sheet metal forming processes (deep drawing, flange forming, stretch drawing, metal spinning and bending). In terms of special processes, the chapters on internal high-pressure forming and high rate forming have been revised and refined. On the other, the book elucidates and presents the state of the art in sheet metal separation processes (shearing and fineblanking). Furthermore, joining by forming has been added to the new edition as a new chapter describing mechanical methods for joining sheet metals. The new chapter “Basic Principles” addresses both sheet metal and bulk forming, in addition to metal physics, plastomechanics and computational basics; ...

  5. Profiling and Racial Profiling: An Interactive Exercise

    Science.gov (United States)

    Semple, Philip

    2013-01-01

    Racial Profiling has been recognized as a serious problem that affects many segments of our society and is especially notable in law enforcement. Governments and police services have pronounced that racial profiling is not acceptable and will not be tolerated. They have gone to great lengths in trying to eradicate racial profiling through…

  6. Etude du profil d'echelle des formes et de mesures d'energie de texture pour l'evaluation semi-automatique des degâts sur les bâtiments dans les images satellitaires de tres haute resolution

    Science.gov (United States)

    Dubois, David

    Dozens of natural disasters occur each year throughout the world. They cause the death of thousands of people and cost billions of dollars in losses and reconstruction. Considerable resources are invested in the various phases of the emergency cycle like response and reconstruction. To avoid mismanagement of human and material resources during the response to a disaster, decisions must be made very quickly. To make appropriate choices, decision makers need up to date information on conditions on the ground. The images acquired by satellite are a possible source for this information. The new satellites equipped with optical sensors having spatial resolution finer than a meter per pixel provide details useful for determining the status of roads and damage to buildings. Unfortunately, visual analysis of these very large images is time consuming and fatigue may increase the rate of human error. In this thesis, we propose a semi-automatic method for the extraction of buildings and damage assessment using geometric, radiometric and texture features. The work includes a review of the literature in order to identify gaps in current approaches and possible solutions, the development of a methodology to solve this difficult problem, the testing of the proposed method on a portion of images of the city of Port-au-Prince, Haiti captured before and after the earthquake of January 12, 2010, assessment of results and their comparison with the literature. The proposed method requires processing of the image in a hierarchical tree shapes through the fast level set transform. Once the image is represented in this way, an algorithm for extracting meaningful forms is used to assign a representative form for each pixel. Geometrical descriptors such as area, perimeter and others from central moments are extracted from these forms. In addition, for damage assessment, energy measurements of texture are calculated on the forms before and after the event. Buildings are extracted using a

  7. Investigation of Detectability of Elementary Composition of Rainbow trout muscle with EDS (Energy Dispersive Spectroscopy Method

    Directory of Open Access Journals (Sweden)

    Saltuk Buğrahan CEYHUN

    2017-06-01

    Full Text Available In present study, it is investigated that detectability of elementary composition of rainbow trout muscle using Energy Dispersive Spectroscopy (EDS. EDS system which has worked with attached to scanning electron microscope can do qualitative and semi-quantitative elementary analyses on selected region of sample using characteristic X-rays. For this purpose, it was performed four point and two mapping analyses from four samples. According to results, it was detected 13 elements which are consist of C, N and O in 87.70 percentage. As a result, although the method is sensitive and reliable, it is concluded that not adequate for elemental analysis alone but can be used as a support for analyzes with systems such as especially atomic absorption and ICP-MS.

  8. "Head käed" tõid Berlinalelt auhinna / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2002-01-01

    Berliini 52. filmifestivali tulemustest. Festivali "Panorama Special" kavas olnud Peeter Simmi "Head käed" saavutas hea publikuedu ning jagas sloveenlase Maja Weiss'i filmiga "Piirivalvur" Manfred Salzgeberi auhinda, mis on mõeldud subtiitrite tegemiseks filmi levitamisel euroopa ekraanidele. Kuldkaru jagasid briti Paul Greengrassi "Verine pühapäev" ja jaapanlase Hayao Miyazaki animafilm "Vaimudest viidud". Parima režissööri Hõbekaru sai Otar Ioseliani

  9. HigherEd 2.0: Using social media in engineering education

    OpenAIRE

    Berger, Edward

    2014-01-01

    Social media (blogs, wikis, video, and a digital authoring culture) has emerged in the last decade as a dominant feature of the technology landscape, especially for our current generation of digital-native students. Leveraging these tools for higher education in general, and engineering education in particular, should be of immediate and pressing concern for engineering educators. This discussion summarizes the HigherEd 2.0 project, the creative convergence of higher education and “web 2.0” t...

  10. Dym, J. y K. Offen (eds.: 2011, Mapping Latin America. A Cartographic Reader

    Directory of Open Access Journals (Sweden)

    Ricardo A. Fagoaga Hernández

    2013-07-01

    Full Text Available Dym, J. y K. Offen (eds.: 2011, Mapping Latin America. A Cartographic Reader, The University of Chicago Press, Chicago/London, xix+338 p., 131 illustrations, ISBN-13: 978-0-226-61821-0; ISBN-10: 0-226-61821-8 (hard cover; ISBN-13: 978-0-226-61822-7, ISBN-10: 0-226-61822-6 (paperback

  11. Emergency Doses (ED) - Revision 3: A calculator code for environmental dose computations

    Energy Technology Data Exchange (ETDEWEB)

    Rittmann, P.D.

    1990-12-01

    The calculator program ED (Emergency Doses) was developed from several HP-41CV calculator programs documented in the report Seven Health Physics Calculator Programs for the HP-41CV, RHO-HS-ST-5P (Rittman 1984). The program was developed to enable estimates of offsite impacts more rapidly and reliably than was possible with the software available for emergency response at that time. The ED - Revision 3, documented in this report, revises the inhalation dose model to match that of ICRP 30, and adds the simple estimates for air concentration downwind from a chemical release. In addition, the method for calculating the Pasquill dispersion parameters was revised to match the GENII code within the limitations of a hand-held calculator (e.g., plume rise and building wake effects are not included). The summary report generator for printed output, which had been present in the code from the original version, was eliminated in Revision 3 to make room for the dispersion model, the chemical release portion, and the methods of looping back to an input menu until there is no further no change. This program runs on the Hewlett-Packard programmable calculators known as the HP-41CV and the HP-41CX. The documentation for ED - Revision 3 includes a guide for users, sample problems, detailed verification tests and results, model descriptions, code description (with program listing), and independent peer review. This software is intended to be used by individuals with some training in the use of air transport models. There are some user inputs that require intelligent application of the model to the actual conditions of the accident. The results calculated using ED - Revision 3 are only correct to the extent allowed by the mathematical models. 9 refs., 36 tabs.

  12. PENGENDALIAN MESIN HOIST HANGER DALAM PROSES PTC/ED MENGGUNAKAN PLC OMRON

    OpenAIRE

    Wahyudi Wahyudi; M. Hasim As’ari

    2012-01-01

    The development of technology demands efficient and work speed, so it needs a system which can handleseveral things.This problem can be covered with PLC (Programmable Logic Control) that can integrateseveral self standing component to be an integrated control system and can be changed the configurationwithout change all instrument. Modify the ladder program can alter system of PLC. This paper showsHoist Hanger system in PTC/ED (Pre Treatment Chemical/Electrocoat Dispotition) process that cont...

  13. TEM EDS analysis of epitaxially-grown self-assembled indium islands

    Directory of Open Access Journals (Sweden)

    Jasmine Sears

    2017-05-01

    Full Text Available Epitaxially-grown self-assembled indium nanostructures, or islands, show promise as nanoantennas. The elemental composition and internal structure of indium islands grown on gallium arsenide are explored using Transmission Electron Microscopy (TEM Energy Dispersive Spectroscopy (EDS. Several sizes of islands are examined, with larger islands exhibiting high (>94% average indium purity and smaller islands containing inhomogeneous gallium and arsenic contamination. These results enable more accurate predictions of indium nanoantenna behavior as a function of growth parameters.

  14. Validating the ABCD(2) Score for predicting stroke risk after transient ischemic attack in the ED.

    Science.gov (United States)

    Ong, Marcus Eng Hock; Chan, Yiong Huak; Lin, Wan Ping; Chung, Wan Ling

    2010-01-01

    The aim of the study was to validate the use of the ABCD(2) score for the prediction of stroke after transient ischemic attack (TIA) in patients presenting to the emergency department (ED). The ABCD(2) scoring is based on 5 factors as follows: age of at least 60 years; blood pressure of at least 140/90 mm Hg; clinical features such as unilateral weakness and speech impairment alone; duration of at least 60 minutes or 10 to 59 minutes; and diabetes. The authors conducted a retrospective observational study of all patients presented to the ED for TIA, as diagnosed by the attending emergency physicians, for a 2-year period. Sensitivity, specificity, and negative predictive value (NPV) were calculated for risk of stroke at 2, 7, 30, and 90 days after presentation. From January 1, 2005, to December 31, 2006, there were 470 patients diagnosed with TIA at the ED. Mean age was 61.0 years (SD, 13.2), with 63.3% males. Age of at least 60 years, unilateral weakness, and duration of at least 60 minutes were found to be significant predictors of stroke at 2 days. An admission rule based on an ABCD(2) score of at least 4 showed sensitivity of 86.4% and NPV of 91.7% for stroke at 7 days. Admission based on a score of at least 3 showed sensitivity of 96.6% and NPV of 96.1%. Admission rate was 69.1% and. 83.6%, respectively. The ABCD(2) rule showed good sensitivity and NPV for stroke at 7 days. However, NPV was not 100%, and there would still be patients being discharged from the ED and returning with a stroke if this cutoff was implemented in our setting.

  15. Representation of Solar Capacity Value in the ReEDS Capacity Expansion Model

    Energy Technology Data Exchange (ETDEWEB)

    Sigrin, B. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Sullivan, P. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Ibanez, E. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Margolis, R. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2014-03-01

    An important issue for electricity system operators is the estimation of renewables' capacity contributions to reliably meeting system demand, or their capacity value. While the capacity value of thermal generation can be estimated easily, assessment of wind and solar requires a more nuanced approach due to the resource variability. Reliability-based methods, particularly assessment of the Effective Load-Carrying Capacity, are considered to be the most robust and widely-accepted techniques for addressing this resource variability. This report compares estimates of solar PV capacity value by the Regional Energy Deployment System (ReEDS) capacity expansion model against two sources. The first comparison is against values published by utilities or other entities for known electrical systems at existing solar penetration levels. The second comparison is against a time-series ELCC simulation tool for high renewable penetration scenarios in the Western Interconnection. Results from the ReEDS model are found to compare well with both comparisons, despite being resolved at a super-hourly temporal resolution. Two results are relevant for other capacity-based models that use a super-hourly resolution to model solar capacity value. First, solar capacity value should not be parameterized as a static value, but must decay with increasing penetration. This is because -- for an afternoon-peaking system -- as solar penetration increases, the system's peak net load shifts to later in the day -- when solar output is lower. Second, long-term planning models should determine system adequacy requirements in each time period in order to approximate LOLP calculations. Within the ReEDS model we resolve these issues by using a capacity value estimate that varies by time-slice. Within each time period the net load and shadow price on ReEDS's planning reserve constraint signals the relative importance of additional firm capacity.

  16. Treating primary headaches in the ED: can droperidol regain its role?

    Science.gov (United States)

    Faine, Brett; Hogrefe, Christopher; Van Heukelom, Jon; Smelser, Jamie

    2012-09-01

    The aim of this study was to describe the use and efficacy of low-dose (≤2 mg) droperidol for the treatment of primary headaches (ie, migraine, cluster, tension-type headache and trigeminal autonomic cephalalgias, and other primary headaches) in the emergency department (ED). A report was generated from a pharmacy database to identify all adult patients who received low-dose droperidol in the ED over a 7-month period; a subsequent retrospective chart review was conducted. Low-dose droperidol was defined as a cumulative dose of ≤2 mg. Patients who received droperidol for any other reason than the treatment of a headache were excluded. Data were analyzed descriptively. Seventy-three cases in which droperidol was administered for the treatment of a headache were identified over the 7-month period. Most doses (92%) administered were 1.25 mg or less. Fifty-three patients (73%) had complete resolution or significant improvement of headache symptoms as subjectively or objectively (eg, numerical pain scale) documented by the treating physician. Eight patients (11%) had minimal improvement in their headaches symptoms; 12 patients (16%) received no relief after the administration of droperidol. The average time to discharge from the ED was 94.8 ± 67.2 minutes. No cardiac arrhythmias were noted. Other adverse events included 2 cases of extrapyramidal side effects; one patient reported restlessness/anxiousness and the other patient had dystonia. The administration of low-dose (≤2 mg) droperidol may be safe and effective for the treatment of primary headaches in the ED. Published by Elsevier Inc.

  17. The accuracy of point-of-care ultrasound to diagnose long bone fractures in the ED.

    Science.gov (United States)

    Waterbrook, Anna L; Adhikari, Srikar; Stolz, Uwe; Adrion, Carrie

    2013-09-01

    To determine the diagnostic accuracy of emergency physician performed point-of care ultrasound (POCUS) for detecting long bone fractures compared to standard radiography. This was a single-blinded, prospective observational study of patients presenting to two emergency departments (ED) with trauma to long bones. The study used a convenience sample of patients seen during the study investigators' scheduled clinical shifts. Patients presenting to the ED with complaints of long bone trauma were included in the study when a study investigator was available in the ED. POCUS examinations of injured long bones were performed using a standard protocol. The investigators documented their interpretation prior to radiographs being performed. After standard radiographs were performed, the final radiology reading by a radiology attending physician was obtained from the medical record. One-hundred six patients were enrolled into the study, and 147 long bone POCUS examinations were performed. Forty-two fractures were present by radiographs and the prevalence of fractures was 29%. The sensitivity was 90.2% (4/41, 95% CI: 76.9-97.3) and specificity was 96.1% (4/102, 95% CI: 90.3-98.9). The positive likelihood ratio was 23.0 (95% CI: 8.8-60.5), and the negative likelihood ratio was 0.102 (95% CI: 0.040, 0.258). The positive predictive value was 90.2% (4/41, 95% CI: 76.9-97.3) and the negative predictive value was 96.1% (4/102, 95% CI: 90.3-98.9). Emergency physicians can accurately evaluate long bone fractures in the ED using POCUS. In particular, long bone fractures can be excluded with a high degree of confidence. © 2013.

  18. DisturbED: A Generalized Framework for Modeling Forest Insects and Pathogens in the Earth System

    Science.gov (United States)

    Matthes, J. H.

    2016-12-01

    Forest insects and pathogens (FIPs) are ubiquitous agents of disturbance that cause major alterations to ecosystem function and billions of dollars in damage annually. Future feedbacks between FIPs, forests, and climate change are not well understood at continental scales, due in part to the absence of the processes modulated by FIPs within Earth System Models (ESMs). To address this challenge, we developed a generalized, globally-scalable framework — DisturbED — in which mechanistic impacts of FIPs on plant physiology are scaled up to ecosystem-level processes so they can be integrated into ESMs. This framework can be used to test a suite of hypotheses concerning the effects of FIPs on forest biogeochemistry, demography, and structure in response to FIPs that vary in their host specificity, timescale and intensity of attack, and sensitivity to climatic change. Both native and invasive FIPs initiate a vast range of ecophysiological responses within individual trees, from slight stress and recovery to rapid mortality. Rather than modeling FIPs as direct agents of mortality, DisturbED couples FIP functional types with changes in individual host plant physiology to simulate resulting changes in ecosystem processes within the Ecosystem Demography (ED) model. This bottom-up modeling framework will allow for investigation of interactions among tree and FIPs physiology; demography and ecosystem dynamics; and their contingency on climatic change.

  19. A new e-learning platform for radiology education (RadEd).

    Science.gov (United States)

    Xiberta, Pau; Boada, Imma

    2016-04-01

    One of the key elements of e-learning platforms is the content provided to the students. Content creation is a time demanding task that requires teachers to prepare material taking into account that it will be accessed on-line. Moreover, the teacher is restricted by the functionalities provided by the e-learning platforms. In contexts such as radiology where images have a key role, the required functionalities are still more specific and difficult to be provided by these platforms. Our purpose is to create a framework to make teacher's tasks easier, specially when he has to deal with contents where images have a main role. In this paper, we present RadEd, a new web-based teaching framework that integrates a smart editor to create case-based exercises that support image interaction such as changing the window width and the grey scale used to render the image, taking measurements on the image, attaching labels to images and selecting parts of the images, amongst others. It also provides functionalities to prepare courses with different topics, exercises and theory material, and also functionalities to control students' work. Different experts have used RadEd and all of them have considered it a very useful and valuable tool to prepare courses where radiological images are the main component. RadEd provides teachers functionalities to prepare more realistic cases and students the ability to make a more specific diagnosis. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  20. CHOICE OF INSTRUCTIONAL MEDIA OF B.ED. STUDENTS OF IGNOU FROM TWO INDIAN METROPOLISES

    Directory of Open Access Journals (Sweden)

    Sutapa BOSE

    2010-10-01

    Full Text Available Indira Gandhi National Open University (IGNOU of India uses multiple media and modes for reaching out to its distant learners. For most of the programmes offered to these learners, print is the master medium and other media supplement it. Instructions for the Bachelor in Education (B.Ed., one of the popular programmes of IGNOU, are also delivered similarly. A survey was undertaken to determine the extent of utilization of instructions provided through various media by the students of B.Ed of two Indian metropolises –Delhi and Kolkata, having high penetration of advanced communication technologies. As the students of B.Ed. happen to be teachers who are supposed to be using ICT for teaching in their schools, the survey aimed to determine whether they were also using ICT for learning. The survey was carried out with a questionnaire with closed and open ended questions. It was found that only print medium was used for learning while the other media of the multimedia package remained mostly unused. The reason for this trend was found to be mainly the perception that the print medium is sufficient for assessment purposes. Suggestions have been made that to utilize the multiple media instructional system, interesting programmes that can hook learners be developed for delivery by electronic media and that gradually ICT may be integrated into the programmes from the present supplementary mode so that complacence in using it is reduced among learners.

  1. Synthesis and characterization of Ce and La modified bismuth titanate

    Directory of Open Access Journals (Sweden)

    Nikolina Pavlović

    2009-06-01

    Full Text Available Bismuth titanate based nanopowders with the different content of La or Ce were synthesized by the modified sol-gel method. After calcination at 600°C, in addition to Aurivillius layered structure, a small quantity of cubic pyrochlore phase was detected in the La modified powders, while this second phase was much more pronounced in the Ce substituted powders. In fact, as the powder with the highest amount of Ce (Bi3CeTi3O12 has the pure pyrochlore phase it seems that the presence of Ce stabilizes the formation of this phase. This different infl uence of cerium and lanthanum could be explained by the incorporation of their ions on the different sites in the titanate structure. Bismuth titanate based ceramics, sintered at 1050°C/2h, had densities above 93% of theoretical density and characteristic plate-like grain morphology. Small quantity of cubic pyrochlore phase was detected only in the Ce modifi ed bismuth titanate ceramics. On the other hand, lanthanum addition caused formation of smaller grain size with pronounced plate-like morphology.

  2. SEM/EDS and optical microscopy analyses of microplastics in ocean trawl and fish guts.

    Science.gov (United States)

    Wang, Zhong-Min; Wagner, Jeff; Ghosal, Sutapa; Bedi, Gagandeep; Wall, Stephen

    2017-12-15

    Microplastic particles from Atlantic and Pacific Ocean trawls, lab-fed fish guts and ocean fish guts have been characterized using optical microscopy and SEM/EDS in terms of size, morphology, and chemistry. We assessed whether these measurements could serve as a rapid screening process for subsequent identification of the likely microplastic candidates by micro-spectroscopy. Optical microscopy enabled morphological classification of the types of particles or fibers present in the sample, as well as the quantification of particle size ranges and fiber lengths. SEM/EDS analysis was used to rule out non-plastic particles and screen the prepared samples for potential microplastic, based on their element signatures and surface characteristics. Chlorinated plastics such as polyvinyl chloride (PVC) could be easily identified with SEM/EDS due to their unique elemental signatures including chlorine, as could mineral species that are falsely identified as plastics by optical microscopy. Particle morphology determined by optical microscopy and SEM suggests the fish ingested particles contained both degradation fragments from larger plastic pieces and also manufactured microplastics. SEM images of microplastic particle surfaces revealed characteristic cracks consistent with environmental exposure, as well as pigment particles consistent with manufactured materials. Most of the microplastic surfaces in the fish guts and ocean trawls were covered with biofilms, radiolarians, and crustaceans. Many of the fish stomachs contained micro-shell pieces which visually resembled microplastics. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. PAs in the ED: do physicians think they increase the malpractice risk?

    Science.gov (United States)

    Gifford, Alisa; Hyde, Mark; Stoehr, James D

    2011-06-01

    This study evaluates emergency physicians' perceptions of the malpractice risk posed by utilization of physician assistants (PAs) in emergency departments (EDs) in 2004 and again in 2009. A 16-question survey was mailed to a random sample of 1,000 active members of the American College of Emergency Physicians in 2004 and again in 2009. In both 2004 and 2009, 70% of the emergency physicians did not believe that PAs, when properly supervised, are more likely to commit malpractice than any other clinician. In both surveys, 80% of the respondents did not believe PAs were more likely to be sued for malpractice. A significant negative correlation was found between perceived risk of malpractice by PAs and the number of years physicians had worked with PAs or had worked in emergency medicine. From 2004 to 2009, the number of respondents practicing with PAs increased by 26%, the number directly supervising a PA in the ED increased by 19%, the number who thought PAs decreased patient wait times increased by 13%, and the number who reported that PAs increased patient satisfaction increased by 10%. As physicians gain clinical experience with PAs, their perceived risk of malpractice tends to decrease. These results may have implications for the utilization of PAs, particularly as EDs become more utilized for noncritical situations.

  4. Application of the TIMI risk score in ED patients with cocaine-associated chest pain.

    Science.gov (United States)

    Chase, Maureen; Brown, Aaron M; Robey, Jennifer L; Zogby, Kara E; Shofer, Frances S; Chmielewski, Lauren; Hollander, Judd E

    2007-11-01

    The TIMI risk score has been validated as a risk stratification tool in emergency department (ED) patients with potential acute coronary syndrome. The goal of this study was to assess its ability to predict adverse cardiovascular outcomes in cocaine-associated chest pain. This was a prospective cohort study of ED patients with chest pain with cocaine use. Data included demographics, medical history, and TIMI risk score. The main outcomes were acute myocardial infarction, revascularization, or death within 30 days of ED presentation. There were 261 patient visits. Patients were 43.2+8 years old, 73% male, 92% black, and 75% smokers. There were 33 patients with the composite outcome. The incidence of 30-day outcomes according to TIMI score is as follows: TIMI 0, 3.7% (95% CI, 0.1-8.3); TIMI 1, 13.2% (5.7-20.7); TIMI 2, 17.1% (4.3-29.8); TIMI 3, 21.4% (4.4-38.4); TIMI 4, 20.0% (0.1-43.6); TIMI 5/6, 50.0% (0.1-100). The TIMI risk score has no clinically useful predictive value in patients with cocaine-associated chest pain.

  5. Mid-term NEAT review: analysing the improvements in hospital ED performance.

    Science.gov (United States)

    Khanna, Sankalp; Boyle, Justin; Good, Norm; Lind, James

    2014-01-01

    Introduced with a promise to reduce overcrowding in the Emergency Department (ED) and the associated morbidity and mortality linked to bed access difficulties, the National Emergency Access Target (NEAT) is now over halfway through transitionary arrangements towards a target of 90% of patients that visit a hospital ED being admitted or discharged within 4 hours. Facilitation and reward funding has ensured hospitals around the country are remodelling workflows to ensure compliance. Recent reports however show that the majority of hospitals are still far from being able to meet this target. We investigate the NEAT journey of 30 Queensland hospitals over the past two years and compare this performance to a previous study that investigated the 4 hour ED discharge performance of these hospitals at various times of day and under varying occupancy conditions. Our findings reveal that, while most hospitals have made significant improvements to their 4 hour discharge performance in 2013, the underlying flow patterns and periods of poor NEAT compliance remain largely unchanged. The work identifies areas for targeted improvement to inform system redesign and workflow planning.

  6. Representation of the Solar Capacity Value in the ReEDS Capacity Expansion Model: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Sigrin, B.; Sullivan, P.; Ibanez, E.; Margolis, R.

    2014-08-01

    An important emerging issue is the estimation of renewables' contributions to reliably meeting system demand, or their capacity value. While the capacity value of thermal generation can be estimated easily, assessment of wind and solar requires a more nuanced approach due to resource variability. Reliability-based methods, particularly, effective load-carrying capacity (ELCC), are considered to be the most robust techniques for addressing this resource variability. The Regional Energy Deployment System (ReEDS) capacity expansion model and other long-term electricity capacity planning models require an approach to estimating CV for generalized PV and system configurations with low computational and data requirements. In this paper we validate treatment of solar photovoltaic (PV) capacity value by ReEDS capacity expansion model by comparing model results to literature for a range of energy penetration levels. Results from the ReEDS model are found to compare well with both comparisons--despite not being resolved at an hourly scale.

  7. Determination of organic compounds in medicinal plants, commercialized in capsulated forms and 'in natura' by wavelength dispersive X-ray fluorescence spectrometry (WDXRF). Determination of quantitative inorganic profiles; Determinacao de componentes organicos em plantas medicinais, comercializadas em forma de po (capsulas) e 'in natura', utilizando a tecnica de fluorescencia de raios X por dispersao de comprimento de onda (WDXRF). Determinacao de perfis inorganicos quantitativos

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, Manuel Octavio M.; Sato, Ivone Mulako; Salvador, Vera Lucia R. [Instituto de Pesquisas Energeticas e Nucleares (IPEN), Sao Paulo, SP (Brazil). Centro de Quimica e Meio Ambiente]. E-mail: lawless@usp.br

    2005-07-01

    X-ray fluorescence technique was used to determine major and trace elements for five Brazilian commercial medicinal plants. The bromobutane (Barbatimao), Ginkgo folium (Ginkgo biloba), Echinodorus macrophyllus (Chapeu de couro), Valeriana officinalis (Valeriana), Cordia salicifolia (Porangaba) samples were collected from three to six different commercial suppliers. The species were collected 'in natura' (leaves, flowers, barks and roots) and capsulated forms. The samples were grinded in liquid N{sub 2} atmosphere and double layer pressed pellet were prepared. The elements Na, Mg, P, S, Cl, K, Ca, Mn, Fe, Ni, Cu, Zn, Rb e Sr concentrations were determined by individual calibration curves. The precision and accuracy of method were evaluated by certified reference material, NIST 1547 - Peach Leaves and the Chauvenet, Cochrane, ANOVA and Z-score statistical tests were applied. Each specimen presented a distinct inorganic profile and a great variation in its composition was observed. The inorganic profile will contribute for the elaboration of a quality and security guide to assure the phytotherapics commercialization. Moreover, these profiles could be used as complementary data to active farmaco compounds profiles for specimen's ratification. (author)

  8. Family profiles in eating disorders: family functioning and psychopathology

    Directory of Open Access Journals (Sweden)

    Cerniglia L

    2017-10-01

    Full Text Available Luca Cerniglia,1 Silvia Cimino,2 Mimma Tafà,2 Eleonora Marzilli,2 Giulia Ballarotto,2 Fabrizia Bracaglia2 1Faculty of Psychology, International Telematic University UNINETTUNO, 2Department of Dynamic and Clinical Psychology, University of Rome “La Sapienza”, Rome, Italy Abstract: Research has studied family functioning in families of patients suffering from eating disorders (EDs, particularly investigating the associations between mothers’ and daughters’ psychopathological symptoms, but limited studies have examined whether there are specific maladaptive psychological profiles characterizing the family as a whole when it includes adolescents with anorexia nervosa (AN, bulimia nervosa (BN, and binge eating disorder (BED. Through the collaboration of a network of public and private consultants, we recruited n=181 adolescents diagnosed for EDs (n=61 with AN, n=60 with BN, and n=60 with BEDs and their parents. Mothers, fathers, and youths were assessed through a self-report measure evaluating family functioning, and adolescents completed a self-report questionnaire assessing psychopathological symptoms. Results showed specific family functioning and psychopathological profiles based on adolescents’ diagnosis. Regression analyses also showed that family functioning characterized by rigidity predicted higher psychopathological symptoms. Our study underlines the importance of involving all members of the family in assessment and intervention programs when adolescent offspring suffer from EDs. Keywords: family functioning, eating disorders, adolescents, psychopathological risk

  9. Maass Forms and Quantum Modular Forms

    Science.gov (United States)

    Rolen, Larry

    This thesis describes several new results in the theory of harmonic Maass forms and related objects. Maass forms have recently led to a flood of applications throughout number theory and combinatorics in recent years, especially following their development by the work of Bruinier and Funke the modern understanding Ramanujan's mock theta functions due to Zwegers. The first of three main theorems discussed in this thesis concerns the integrality properties of singular moduli. These are well-known to be algebraic integers, and they play a beautiful role in complex multiplication and explicit class field theory for imaginary quadratic fields. One can also study "singular moduli" for special non-holomorphic functions, which are algebraic but are not necessarily algebraic integers. Here we will explain the phenomenon of integrality properties and provide a sharp bound on denominators of symmetric functions in singular moduli. The second main theme of the thesis concerns Zagier's recent definition of a quantum modular form. Since their definition in 2010 by Zagier, quantum modular forms have been connected to numerous different topics such as strongly unimodal sequences, ranks, cranks, and asymptotics for mock theta functions. Motivated by Zagier's example of the quantum modularity of Kontsevich's "strange" function F(q), we revisit work of Andrews, Jimenez-Urroz, and Ono to construct a natural vector-valued quantum modular form whose components. The final chapter of this thesis is devoted to a study of asymptotics of mock theta functions near roots of unity. In his famous deathbed letter, Ramanujan introduced the notion of a mock theta function, and he offered some alleged examples. The theory of mock theta functions has been brought to fruition using the framework of harmonic Maass forms, thanks to Zwegers. Despite this understanding, little attention has been given to Ramanujan's original definition. Here we prove that Ramanujan's examples do indeed satisfy his

  10. Determination of ED50 and ED95 of 0.5% Ropivacaine in Adductor Canal Block to Produce Quadriceps Weakness: A Dose-Finding Study.

    Science.gov (United States)

    Johnston, David F; Sondekoppam, Rakesh V; Giffin, Robert; Litchfield, Robert; Ganapathy, Sugantha

    Adductor canal block (ACB) is popular for knee analgesia because of its favorable effect on quadriceps strength. The aim of this study was to find the minimum volume of local anesthetic, which can be injected into the ACB that would result in quadriceps weakness. This nonrandomized study used an up-and-down sequential allocation design. Twenty-six patients scheduled to undergo arthroscopic knee surgery received an ultrasound-guided ACB preoperatively. The initial volume of ropivacaine 0.5% injected was 30 mL, which was subsequently increased or decreased by 2 mL, depending on whether the previous subject had a 30% reduction in quadriceps function. The minimum effective volume in 50% of patients was determined using Dixon-Massey up-and-down method. The effective volume in 95% of patients was then calculated using probit transformation. The ED50 (minimum effective anesthetic volume in 50% of the subjects) needed for a 30% decrease in quadriceps power was 46.5 mL (95% confidence interval, 45.01-50.43 mL), and estimated ED95 (minimum effective anesthetic volume in 95% of the subjects) was 50.32 mL (95% confidence interval, 48.66-67.26 mL). The local anesthetic volume injected correlated with degree of quadriceps weakness at 20 minutes postblock (P unit (P = 0.032). Significant quadriceps weakness is unlikely when clinically representative volumes of 0.5% ropivacaine is used for ACB performed using sonographic landmarks. This study was registered at ClinicalTrials.gov, identifier NCT02541552.

  11. DNW--"did not wait" or "demographic needing work": a study of the profile of patients who did not wait to be seen in an Irish emergency department.

    LENUS (Irish Health Repository)

    Gilligan, P

    2009-11-01

    Patients who fail to wait for medical assessment in the emergency department (ED) have been referred to in the international literature as "did not wait" (DNW) or "left without being seen" (LWBS) patients or, indeed, simply as "walkouts". This is taken as a performance indicator internationally. In common with many countries, Ireland has very considerable problems in the delivery of ED care due largely to inadequate resources and the inappropriate use of EDs as holding bays for admitted patients. This is the first study of this size to profile the DNW phenomenon in Ireland.

  12. An innovative data collection method for investigating unresolved pain after ED discharge: a pilot study.

    Science.gov (United States)

    Stapleton, Stephen J; Degitz, R Joseph

    2014-11-01

    Research focused on improving the outcome of patients with pain is an important aspect of emergency care, yet little information has been published to quantify pain severity, patient improvement, and return to independent function after ED discharge. Because of the paucity of available clinical data, this pilot study was designed to determine the acceptability and feasibility of using electronic data collection procedures. Specifically, we examined the willingness of discharged ED patients to use portable touch-screen computers as an alternative to traditional "paper and pencil" or telephone data collection methods to report postdischarge pain. Participants in this prospective pilot study all reported acute pain that was unresolved at the time of ED discharge. Descriptive data were self-entered on touch-screen computers at ED discharge and 7 days later in subjects' homes. Participants completed 4 Patient-Reported Outcomes Measurement Information System (PROMIS Network, Silver Spring, MD), questionnaires and the computer acceptability scale (CAS), using the Assessment Center platform program (National Institute of Health, Bethesda, MD) for instrument administration, data storage, and information retrieval. Determinants of study success were willingness of the participants to use touch-screen computers, questionnaire completion time, and completeness of the data. Participants (N = 25) used touch-screen computers to complete 18 questions at the time of ED discharge. The mean completion time was 3.54 (± 1.13) minutes. Participants averaged 5.83 (± 2.00) minutes to complete the follow-up questionnaires. Ninety-two percent of subjects reported that the touch-screen computer was easy to use. We encountered no issues with data management using the Assessment Center platform. Touch-screen computers are a feasible and acceptable approach to collecting information about how patients self-manage unresolved pain after discharge from an emergency department. This methodology

  13. INSIST-ED: Italian Society of Andrology registry on penile prosthesis surgery. First data analysis

    Directory of Open Access Journals (Sweden)

    Edoardo Pescatori

    2016-07-01

    Full Text Available Objectives: The Italian Society of Andrology, i.e. “Società Italiana di Andrologia” (S.I.A., launched on December 2014 a prospective, multicenter, monitored and internal review board approved Registry for penile implants, the “INSIST-ED” (Italian Nationwide Systematic Inventarisation of Surgical Treatment for ED Registry. Purpose of this first report is to present a baseline data analysis of the characteristics of penile implant surgery in Italy. Material and methods: The INSIST-ED Registry is open to all surgeons implanting penile prostheses (all brands, all models in Italy, providing anonymous patient, device, surgical procedure, outcome, follow-up data, for both first and revision surgeries. A Registry project Board overviews all the steps of the project, and a Registry Monitor interacts with the Registry implanting surgeons. Results: As by April 8, 2016, 31 implanting surgeons actively joined the Registry, entering 367 surgical procedures in its database, that comprise: 310 first implants, 43 prosthesis substitutions, 14 device explants without substitution. Implanted devices account for: 288 three-component devices (81,3%, 20 two-component devices (5,4%, 45 non-hydraulic devices (12,3%. Leading primary ED etiologies in first implant surgeries resulted: former radical pelvic surgery in 111 cases (35,8%, Peyronie’s disease in 66 cases (21,3%, diabetes in 39 cases (12,6%. Two intraoperative complications have been recorded. Main reasons for 57 revision surgeries were: device failure (52,6%, erosion (19,3%, infection (12,3%, patient dissatisfaction (10,5%. Surgical settings for patients undergoing a first penile implant were: public hospitals in 251 cases (81%, private environments in 59 cases (19%. Conclusions: The INSIST-ED Registry represents the first European experience of penile prosthesis Registry. This baseline data analysis shows that: three-pieces inflatable prosthesis is the most implanted device, leading etiology of

  14. Factors associated with self-reported pain scores among ED patients.

    Science.gov (United States)

    Marco, Catherine A; Nagel, Jacqueline; Klink, Ellen; Baehren, David

    2012-02-01

    Pain is a common presenting complaint among emergency department (ED) patients. The verbal numeric pain scale is commonly used in the ED to assess self-reported pain. This study was undertaken to describe and compare pain scores in a variety of painful conditions and identify factors associated with self-reported pain scores. The study was a prospective, observational, descriptive survey study conducted at an urban university hospital ED. Eligible participants included consenting adults 18 years and older, with an acute painful condition, who spoke English, and were not in severe distress. Through a structured interview, collected data included pain score; diagnosis; medical history; previous painful experiences; and demographic information including age, insurance status, and highest level of education completed. Among 268 eligible participants, 263 (98%) consented and completed the study protocol. Seventy-one percent of participants were 50 years old or younger; 55%, women; and 68%, white. Fifty-four percent had private insurance, and 81%, high school education or higher. The most common chief complaints were soft tissue injury (33%), abdominal pain (18%), and chest pain (13%). The median self-reported pain score was 7/10 (mean, 6.7; interquartile range, 6-9; range, 0-10). The most common previous painful experiences were childbirth (21%), major trauma (18%), and surgery (14%). Participants cited reasons for self-reported pain scores, including current feeling of pain (62%), comparison to previous pain (31%), and comparison to hypothetical pain (12%). The number of previous ED visits was positively correlated with current pain score (Spearman correlation R = 0.28; P associated with the highest pain scores included dental pain (mean pain score, 8.5) and back pain (mean pain score, 7.6). Chief complaints associated with the lowest pain scores included chest pain (mean pain score, 5.2) and other medical conditions (mean pain score, 5.3). Factors associated with

  15. Forms of Arthritis

    Science.gov (United States)

    ... this page please turn Javascript on. Forms of Arthritis Past Issues / Fall 2006 Table of Contents Today, ... of Linda Saisselin Osteoarthritis (OA) — the form of arthritis typically occurring during middle or old age, this ...

  16. Form postponement: a reconceptualization

    OpenAIRE

    FABRIZIO SALVADOR

    2004-01-01

    Form postponement has been widely acknowledged as one of the main avenues to mitigate the adverse effects of product proliferation or customization on operational performance. As it often happens with long debated concepts, the proposed definitions of form postponement sometimes display substantial differences. This paper aims at moving a step forward towards a more precise definition of form postponement in the domain of tangible products. A first result on this way is that form postponement...

  17. Unified form language

    DEFF Research Database (Denmark)

    Alnæs, Martin S.; Logg, Anders; Ølgaard, Kristian Breum

    2014-01-01

    We present the Unied Form Language (UFL), which is a domain-specic language for representing weak formulations of partial dierential equations with a view to numerical approximation. Features of UFL include support for variational forms and functionals, automatic dierentiation of forms and expres...... libraries to generate concrete low-level implementations. Some application examples are presented and libraries that support UFL are highlighted....

  18. Modular forms on Schiermonnikoog

    NARCIS (Netherlands)

    Edixhoven, B.; van der Geer, G.; Moonen, B.

    2008-01-01

    Modular forms are functions with an enormous amount of symmetry that play a central role in number theory, connecting it with analysis and geometry. They have played a prominent role in mathematics since the 19th century and their study continues to flourish today. Modular forms formed the

  19. Mesonic Form Factors

    Energy Technology Data Exchange (ETDEWEB)

    Frederic D. R. Bonnet; Robert G. Edwards; George T. Fleming; Randal Lewis; David Richards

    2003-07-22

    We have started a program to compute the electromagnetic form factors of mesons. We discuss the techniques used to compute the pion form factor and present preliminary results computed with domain wall valence fermions on MILC asqtad lattices, as well as Wilson fermions on quenched lattices. These methods can easily be extended to rho-to-gamma-pi transition form factors.

  20. Lung-protective ventilation initiated in the emergency department (LOV-ED): a study protocol for a quasi-experimental, before-after trial aimed at reducing pulmonary complications.

    Science.gov (United States)

    Fuller, Brian M; Ferguson, Ian; Mohr, Nicholas M; Stephens, Robert J; Briscoe, Cristopher C; Kolomiets, Angelina A; Hotchkiss, Richard S; Kollef, Marin H

    2016-04-11

    In critically ill patients, acute respiratory distress syndrome (ARDS) and ventilator-associated conditions (VACs) are associated with increased mortality, survivor morbidity and healthcare resource utilisation. Studies conclusively demonstrate that initial ventilator settings in patients with ARDS, and at risk for it, impact outcome. No studies have been conducted in the emergency department (ED) to determine if lung-protective ventilation in patients at risk for ARDS can reduce its incidence. Since the ED is the entry point to the intensive care unit for hundreds of thousands of mechanically ventilated patients annually in the USA, this represents a knowledge gap in this arena. A lung-protective ventilation strategy was instituted in our ED in 2014. It aims to address the parameters in need of quality improvement, as demonstrated by our previous research: (1) prevention of volutrauma; (2) appropriate positive end-expiratory pressure setting; (3) prevention of hyperoxia; and (4) aspiration precautions. The lung-protective ventilation initiated in the emergency department (LOV-ED) trial is a single-centre, quasi-experimental before-after study testing the hypothesis that lung-protective ventilation, initiated in the ED, is associated with reduced pulmonary complications. An intervention cohort of 513 mechanically ventilated adult ED patients will be compared with over 1000 preintervention control patients. The primary outcome is a composite outcome of pulmonary complications after admission (ARDS and VACs). Multivariable logistic regression with propensity score adjustment will test the hypothesis that ED lung-protective ventilation decreases the incidence of pulmonary complications. Approval of the study was obtained prior to data collection on the first patient. As the study is a before-after observational study, examining the effect of treatment changes over time, it is being conducted with waiver of informed consent. This work will be disseminated by

  1. Dimensionality and scale properties of the Edinburgh Depression Scale (EDS) in patients with type 2 diabetes mellitus

    DEFF Research Database (Denmark)

    de Cock, Evi S A; Emons, Wilco H M; Nefs, Giesje

    2011-01-01

    Scale (EDS) is a widely used method for screening depression. However, there is still debate about the dimensionality of the test. Furthermore, the EDS was originally developed to screen for depression in postpartum women. Empirical evidence that the EDS has comparable measurement properties in both......BACKGROUND: Depression is a common complication in type 2 diabetes (DM2), affecting 10-30% of patients. Since depression is underrecognized and undertreated, it is important that reliable and validated depression screening tools are available for use in patients with DM2. The Edinburgh Depression...... to laugh or enjoy) and sleeping problems were the most informative indicators for being able to differentiate between the diagnostic groups of mild and severe depression. CONCLUSIONS: The EDS constitutes a sound scale for measuring an attribute of general depression. Persons can be reliably measured using...

  2. Berliini filmifestivalil näeb ka Peeter Simmi filmi "Head käed" / Triin Tael

    Index Scriptorium Estoniae

    Tael, Triin

    2002-01-01

    Berliini 52. filmifestival algas eile sakslase Tom Tykweri mängufilmiga "Taevas". Esmakordselt on festivali "Panorama" kavas eesti mängufilm, milleks on Peeter Simmi "Head käed". Eesti filmid on esil ka festivali suurel filmiturul

  3. Review: Iwanaga, Kazuki (ed. (2008, Women’s Political Participation and Representation in Asia. Obstacles and Challenges

    Directory of Open Access Journals (Sweden)

    Dagmar Hellmann-Rajanayagam

    2010-04-01

    Full Text Available Review of the edited volume: Iwanaga, Kazuki (ed. (2008, Women’s Political Participation and Representation in Asia. Obstacles and Challenges, Copenhagen: NIAS Press, = Women and Politics in Asia No. 2, ISBN 9788776940164, XVII and 314 pages.

  4. Thomas Crombez, Luk van den Dries (eds., Mass Theatre in Interwar Europe: Flanders and the Netherlands in an International Perspective

    Directory of Open Access Journals (Sweden)

    Maartje Abbenhuis

    2015-09-01

    Full Text Available Thomas Crombez, Luk van den Dries (eds., Mass Theatre in Interwar Europe: Flanders and the Netherlands in an International Perspective (Leuven: Universitaire pers Leuven, 2014, 164 pp., ISBN 978 90 5867 992 5.

  5. A simple method to assess in vivo proliferation in lung vasculature with EdU: the case of MMC-induced PVOD in rat.

    Science.gov (United States)

    Fabrice, Antigny; Benoît, Ranchoux; Valérie, Nadeau; Lau, Edmund; Sébastien, Bonnet; Frédéric, Perros

    2015-01-01

    5-Ethynyl-2'-deoxyuridine (EdU) incorporation is becoming the gold standard method for in vitro and in vivo visualization of proliferating cells. The small size of the fluorescent azides used for detection results in a high degree of specimen penetration. It can be used to easily detect DNA replication in large tissue samples or organ explants with low proliferation and turnover of cells formerly believed to be in a "terminal" state of differentiation. Here we describe a protocol for the localization and identification of proliferating cells in quiescent or injured pulmonary vasculature, in a model of pulmonary veno-occlusive disease (PVOD). PVOD is an uncommon form of pulmonary hypertension characterized by progressive obstruction of small pulmonary veins. We previously reported that mitomycin-C (MMC) therapy is associated with PVOD in human. We demonstrated that MMC can induce PVOD in rats, which currently represents the sole animal model that recapitulates human PVOD lesions. Using the EdU assay, we demonstrated that MMC-exposed lungs displayed areas of exuberant microvascular endothelial cell proliferation which mimics pulmonary capillary hemangiomatosis, one of the pathologic hallmarks of human PVOD. In vivo pulmonary cell proliferation measurement represents an interesting methodology to investigate the potential efficacy of therapies aimed at normalizing pathologic angioproliferation.

  6. Screening and detection of delirium in older ED patients: performance of the modified Confusion Assessment Method for the Emergency Department (mCAM-ED). A two-step tool.

    Science.gov (United States)

    Hasemann, Wolfgang; Grossmann, Florian F; Stadler, Rahel; Bingisser, Roland; Breil, Dieter; Hafner, Martina; Kressig, Reto W; Nickel, Christian H

    2017-12-30

    Delirium is frequent in older Emergency Department (ED) patients, but detection rates for delirium in the ED are low. To aid in identifying delirium, we developed and implemented a two-step systematic delirium screening and assessment tool in our ED: the modified Confusion Assessment Method for the Emergency Department (mCAM-ED). Components of the mCAM-ED include: (1) screening for inattention, the main feature of delirium, which was performed with the Months Backwards Test (MBT); (2) delirium assessment based on a structured interview with questions from the Mental Status Questionnaire by Kahn et al. and the Comprehension Test by Hart et al. The aims of our study are (1) to investigate the performance criteria of the mCAM-ED tool in a consecutive sample of older ED patients, (2) to evaluate the performance of the mCAM-ED in patients with and without dementia and (3) to test whether this tool is efficient in keeping evaluation time to a minimum and reducing screening and assessment burden on the patient. For this prospective validation study, we recruited a consecutive sample of ED patients aged 65 and older during an 11-day period in November 2015. Trained nurses assessed patients with the mCAM-ED. Results were compared to the reference standard [i.e. the geriatricians' delirium diagnosis based on the criteria of the Text Revision of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR)]. Performance criteria were computed. We included 286 consecutive ED patients aged 65 and older. The median age was 80.02 (Q1 = 72.15; Q3 = 86.76), 58.7% of included patients were female, 14.3% had dementia. We found a delirium prevalence of 7.0%. In patients with dementia, specificity and positive likelihood ratio were lower. When compared to the reference standard, delirium assessment with the mCAM-ED has a 0.98 specificity and a 39.9 positive likelihood ratio. In 80.0% of all cases, the first step of the mCAM-ED, i.e. screening for inattention with the MBT

  7. Risk factors associated with difficult venous access in adult ED patients.

    Science.gov (United States)

    Fields, J Matthew; Piela, Nicole E; Au, Arthur K; Ku, Bon S

    2014-10-01

    The objective was to determine risk factors associated with difficult venous access (DVA) in the emergency department (ED). This was a prospective, observational study conducted in the ED of an urban tertiary care hospital. Adult patients undergoing intravenous (IV) placement were consecutively enrolled during periods of block enrollment. The primary outcome was DVA, defined as 3 or more IV attempts or use of a method of rescue vascular access to establish IV access. Univariate and multivariate analyses for factors predicting DVA were performed using logistic regression. A total of 743 patients were enrolled, of which 88 (11.8%) met the criteria for DVA. In the adjusted analysis, only 3 medical conditions were significantly associated with DVA: diabetes (odds ratio [OR] 1.72, 95% confidence interval [CI] 1.1-2.8), sickle cell disease (OR 3.8, 95% CI 1.5-9.5), and history of IV drug abuse (OR 2.5, 95% CI 1.1-5.7). Notably, age, body mass index, and dialysis were not. Of patients who reported a history of requiring multiple IV attempts in the past for IV access, 14% met criteria for DVA on this visit (OR 7.7 95% CI 3-18). Of the patients who reported a history of IV insertion into the external jugular, ultrasound-guided IV placement, or a central venous catheter for IV access, 26% had DVA on this visit (OR 16.7, 95% CI 6.8-41). Nearly 1 of every 9 to 10 adults in an urban ED had DVA. Diabetes, IV drug abuse, and sickle cell disease were found to be significantly associated with DVA. Copyright © 2014 Elsevier Inc. All rights reserved.

  8. Qualitative analysis of adhesive interface nanoleakage using FE-SEM/EDS.

    Science.gov (United States)

    Yuan, Yang; Shimada, Yasushi; Ichinose, Shizuko; Tagami, Junji

    2007-05-01

    The purpose of this study was to evaluate the quality of short term sealing of current adhesives. Five adhesive systems were used and evaluated in this study; two kinds of two-step adhesives (Single Bond and Clearfil SE Bond) and three one-step adhesives (Clearfil S3 Bond, G Bond and One-Up Bond F-plus). Flat occlusal superficial dentin surfaces from extracted human third molars were finished with wet 600-grit silicon-carbide paper and bonded with one of the adhesives. After 24h storage at 37 degrees C in water, the bonded assemblies were sectioned into approximately 1mm thick slabs. Two central slabs from each tooth were chosen and immersed into 50% (w/v) solution of silver ammoniacal nitrate for 18 h and exposed to photodeveloping solution for 6h. The specimens were then slightly polished, argon ion-etched. In order to examine the nanoleakage within the resin/dentin interface, penetration of silver was observed in a field emission (FE)-SEM using yttrium-aluminium-garnet (YAG) backscattered electron mode. EDS analysis was also carried out in parallel to identify the existence of metallic silver particles. The penetration pattern of silver depended on the adhesive used, indicating different nanoleakage in different adhesive systems. Single Bond, One-Up Bond F-plus and G Bond showed clear silver uptake in both the adhesive and hybrid layer. Clearfil SE Bond showed less silver penetration and slight silver peak on the elemental energy spectroscopy of EDS. Clearfil S3 Bond did not display clear silver penetration under 2000x magnification by FE-SEM, and no existence of metallic silver of the Clearfil S3 Bond group by EDS, could be detected. The nanoleakage, as well as its location depends on the adhesives. Different nanoleakage expressions were revealed between two-step and one-step adhesives and also among one-step adhesives themselves.

  9. Rates and Correlates of Violent Behaviors among Adolescents Treated in an Urban ED

    Science.gov (United States)

    Walton, Maureen A.; Cunningham, Rebecca M.; Goldstein, Abby L.; Chermack, Stephen T.; Zimmerman, Marc; Bingham, C. Raymond; Shope, Jean T.; Stanley, Rachel; Blow, Frederic C.

    2010-01-01

    Purpose Violence is a leading cause of death for adolescents in inner-city settings. This paper describes violent behaviors in relation to other risk behaviors (e.g., substance use) among adolescents screened in an urban ED. Methods Patients ages 14–18 were approached to self-administer a computerized survey assessing violent behaviors (i.e., physical aggression), substance use (cigarettes, alcohol, marijuana), and weapon carriage. Results 1128 adolescents (83.8% participation rate; 45.9% male; 58.0% African-American) were surveyed. In the past year, 75.3% of adolescents reported peer violence, 27.6% reported dating violence, and 23.5% carried a weapon. In the past year, 28.0% drank alcohol, 14.4% binge drank, 5.7% reported alcohol-related fighting, and 36.9% smoked marijuana. Logistic regression analyses predicting violent behaviors were significant. Teens reporting peer violence were more likely to be younger, African-American, on public assistance, carry a weapon, binge drink, and smoke marijuana. Teens reporting dating violence were more likely to be female, African-American, carry a weapon, binge drink, screen positive for alcohol problems, and smoke marijuana. Teens reporting alcohol-related fighting were more likely to carry a weapon, binge drink, screen positive for alcohol problems, and smoke marijuana. Conclusions Adolescents presenting to an urban ED have elevated rates of violent behaviors. Substance use (i.e., binge drinking and smoking marijuana) is an important risk factor for violent behaviors among urban adolescents. Universal screening and intervention protocols to address multiple risk behaviors, including violent behaviors and substance use, may be useful to prevent injury among adolescents presenting to the urban ED. PMID:19541253

  10. Forms of Life, Forms of Reality

    Directory of Open Access Journals (Sweden)

    Piergiorgio Donatelli

    2015-10-01

    Full Text Available The article explores aspects of the notion of forms of life in the Wittgensteinian tradition especially following Iris Murdoch’s lead. On the one hand, the notion signals the hardness and inexhaustible character of reality, as the background needed in order to make sense of our lives in various ways. On the other, the hardness of reality is the object of a moral work of apprehension and deepening to the point at which its distinctive character dissolves into the family of connections we have gained for ourselves. The two movements of thought are connected and necessary.

  11. Evaluation of Laser Profile and Deflection Measuring System

    Science.gov (United States)

    1984-09-01

    LRSERS F, BC TEST 5 20.0 LASER9S fiBC TEST -A-5 PROFILES VITH NO CORRECTIONS ST. LARWENCE ROArO WES LASERS ABCO TEST 6 * 2Q. 4-50.@ DITAC - ET 1 A...LASERS ABCO TEST 3 * .0 1-4~ Lui z 󈧎. 160.0 019𔄁 8 . 0 . DIT*C FEE X L PROFILES HIGH PRSS FILTERED RUNWRY. TY’NDRLL FIR FORCE BASE "LASERS ABCD TEST 3... ABCO TEST 2 40. . V.@.. Cn1RR EFT ED FPRONFLE EPIM ’D-2 PROFILE MEASUFRED ,I-TH RnO AND LEVELRUNWAY AT TYNDALL IR FORCE BAHE LASERS ABCD TEST 3 Il S

  12. Self-reported quality of life, anxiety and depression in individuals with Ehlers-Danlos syndrome (EDS): a questionnaire study.

    Science.gov (United States)

    Berglund, Britta; Pettersson, Carina; Pigg, Maritta; Kristiansson, Per

    2015-04-15

    Many individuals with Ehlers-Danlos Syndrome (EDS) are hypermobile, suffer from long term pain, and have complex health problems. Since these sometimes have no objective physical signs, individuals with EDS sometimes are referred for psychiatric evaluation. The aim was therefore to identify the level of anxiety and quality of life in a Swedish group of individuals with EDS. A postal survey in 2008 was distributed to 365 members over 18 years of the Swedish National EDS Association and 250 with EDS diagnosis responded. Two questionnaires, the Hospital Anxiety and Depression Scale (HADS) and SF-36, were used. A Swedish population study was used to compare results from SF-36. Independent Student's t-test was used to compare differences between groups, possible relationships were tested using Spearman's correlation coefficient and the General Linear Model was used for regression analyses. Higher scores on HADS represent higher levels of anxiety and depression and higher scores on SF-36 represent higher quality of health. Of the respondents 74.8% scored high on anxiety and 22.4% scored high on depression on the HADS. Age, tiredness and back pain was independently associated with the HAD anxiety score in a multiple regression analysis, When comparing the SF-36 scores from the EDS group and a Swedish population group, the EDS group scored significantly lower, indicating lower health-related quality of health than the general population (p depression were detected in individuals with EDS. The importance to explore the factors behind these results and what initiatives can be taken to alleviate the situation for this group is emphasized.

  13. A Novel Method to Establish a Rat ED Model Using Internal Iliac Artery Ligation Combined with Hyperlipidemia

    OpenAIRE

    Hu, Chao; Wang, Feixiang; Dong, Yehao; Dai, Jican

    2014-01-01

    OBJECTIVE: To investigate a novel method, namely using bilateral internal iliac artery ligation combined with a high-fat diet (BCH), for establishing a rat model of erectile dysfunction (ED) that, compared to classical approaches, more closely mimics the chronic pathophysiology of human ED after acute ischemic insult. MATERIALS AND METHODS: Forty 4-month-old male Sprague Dawley rats were randomly placed into five groups (n = 8 per group): normal control (NC), bilateral internal iliac artery l...

  14. Review: Michael Crandall & Karen E. Fisher (Eds) Digital Inclusion: Measuring the Impact of Information and Community Technology

    DEFF Research Database (Denmark)

    Pors, Niels Ole

    2010-01-01

    Review: Michael Crandall & Karen E. Fisher (Eds) Digital Inclusion: Measuring the Impact of Information and Community Technology. Medford. Information Today. ASIS&T Monographs, 2009. 185 pages. $ 59.50. ISBN 978-1-57387-373-4......Review: Michael Crandall & Karen E. Fisher (Eds) Digital Inclusion: Measuring the Impact of Information and Community Technology. Medford. Information Today. ASIS&T Monographs, 2009. 185 pages. $ 59.50. ISBN 978-1-57387-373-4...

  15. Evidence of salicylic acid pathway with EDS1 and PAD4 proteins by molecular dynamics simulation for grape improvement.

    Science.gov (United States)

    Tandon, Gitanjali; Jaiswal, Sarika; Iquebal, M A; Kumar, Sunil; Kaur, Sukhdeep; Rai, Anil; Kumar, Dinesh

    2015-01-01

    Biotic stress is a major cause of heavy loss in grape productivity. In order to develop biotic stress-resistant grape varieties, the key defense genes along with its pathway have to be deciphered. In angiosperm plants, lipase-like protein phytoalexin deficient 4 (PAD4) is well known to be essential for systemic resistance against biotic stress. PAD4 functions together with its interacting partner protein enhanced disease susceptibility 1 (EDS1) to promote salicylic acid (SA)-dependent and SA-independent defense pathway. Existence and structure of key protein of systemic resistance EDS1 and PAD4 are not known in grapes. Before SA pathway studies are taken in grape, molecular evidence of EDS1: PAD4 complex is to be established. To establish this, EDS1 protein sequence was retrieved from NCBI and homologous PAD4 protein was generated using Arabidopsis thaliana as template and conserved domains were confirmed. In this study, computational methods were used to model EDS1 and PAD4 and simulated the interactions of EDS1 and PAD4. Since no structural details of the proteins were available, homology modeling was employed to construct three-dimensional structures. Further, molecular dynamic simulations were performed to study the dynamic behavior of the EDS1 and PAD4. The modeled proteins were validated and subjected to molecular docking analysis. Molecular evidence of stable complex of EDS1:PAD4 in grape supporting SA defense pathway in response to biotic stress is reported in this study. If SA defense pathway genes are explored, then markers of genes involved can play pivotal role in grape variety development especially against biotic stress leading to higher productivity.

  16. Micro metal forming

    CERN Document Server

    2013-01-01

    Micro Metal Forming, i. e. forming of parts and features with dimensions below 1 mm, is a young area of research in the wide field of metal forming technologies, expanding the limits for applying metal forming towards micro technology. The essential challenges arise from the reduced geometrical size and the increased lot size. In order to enable potential users to apply micro metal forming in production, information about the following topics are given: tribological behavior: friction between tool and work piece as well as tool wear mechanical behavior: strength and formability of the work piece material, durability of the work pieces size effects: basic description of effects occurring due to the fact, that the quantitative relation between different features changes with decreasing size process windows and limits for forming processes tool making methods numerical modeling of processes and process chains quality assurance and metrology All topics are discussed with respect to the questions relevant to micro...

  17. Period Determination for (23621) 1996 PA, (29564) 1998 ED6 and (31775) 1999 JN122

    Science.gov (United States)

    Marchini, Alessandro; Papini, Riccardo; Salvaggio, Fabio

    2018-01-01

    Photometric observations of three asteroids were conducted from the Astronomical Observatory of the University of Siena (Italy) in order to determine their synodic rotation periods. For (23621) 1996 PA, a Marscrosser asteroid, we found a period of 2.666 ± 0.001 h with an amplitude of 0.10 mag. For the two main-belt asteroids (29564) 1998 ED6 and (31775) 1999 JN122, we found, respectively, a period of 8.434 ± 0.002 h with an amplitude of 0.57 mag and a period of 4.319 ± 0.01 h with an amplitude of 0.12 mag.

  18. MobilED – a mobile tools and services platform for formal and informal learning

    CSIR Research Space (South Africa)

    Ford, M

    2006-10-01

    Full Text Available and the audio played. The teacher could add an audio/video annotation to add his/her ideas to the lesson plan. 2. Making existing educational video/animation “bytes” available to teachers and learners via MMS and data services. Interest in the project has... will discuss the vision of MobilED, cover the role of mobile phones in young people’s everyday knowledge acquisition and problem-solving situations, the applicability of this in an educational environment with a specific focus on the differences...

  19. Application of SEM/EDS to environmental geochemistry of heavy metals

    Directory of Open Access Journals (Sweden)

    Mateja Gosar

    2009-06-01

    Full Text Available Heavy metals represent a ubiquitous constituent of the near-surface environment, present in widely varyingconcentrations that typically have little impact on human behaviour and health. However, the mining of metals anduse of these metals in industrial processes has produced significant anthropogenic inputs of metals to both localand global environments. As such, a rigorous overview of the current accumulation of heavy metals and knowledgeof mineralogy of heavy metal-bearing phases is important for understanding their stability, solubility, mobility,bioavailability and toxicity. These data are of fundamental importance for environmental risk assessment and evaluationof future scenarios. Since conventional geochemical analyses provide limited information, other analyticalmethods have to be utilized for the characterisation of heavy metal-bearing phases. Significant analytical methodfor identification and characterisation of heavy metals in environmental media is a scanning electron microscopecoupled with energy dispersive X-ray spectrometer (SEM/EDS, an apparatus for qualitative and semi-quantitative chemical analysis at microne level, newly introduced to Geological Survey of Slovenia. Use of SEM/EDS was already introduced to environmental studies world-wide. In Slovenia, SEM/EDS analyses of environmental media werefirstly carried out on the Meža River stream sediments and snow deposits from Ljubljana urban area.Heavy metal-bearing phases in the Meža River stream sediments were apportioned to three source areas: Mežica mining/smelting area (geogenic-technogenic origin, Ravne ironworks area (technogenic origin and the Meža River catchment area (geogenic origin, which corresponds to data obtained by conventional geochemical and multivariate statistical methods. Airborne particles, identified in urban snow deposits, were interpreted as geogenic particles, represented by fragments of heavy metal-bearing minerals, and technogenic particles that

  20. Vlivy jaderné energetiky na životní prostředí

    OpenAIRE

    Malkova, Kristina

    2013-01-01

    Title: Environmental impacts of nuclear energy Author: Malkova Kristina Supervisor: Ing. Luboš Matějíček, Dr., Ústav pro životní prostředí Přírodovědecké fakulty Univerzity Karlovy v Praze, Benátská 2, 128 01 Praha 2 Supervisor's e-mail adress: Abstract: The thesis is focused on study the impact of nuclear energy on the environment regard to non - renewable and renewable energy sources. The work includes evaluation of the entire fuel cycle of the use of various technolo...

  1. ESSEA On-Line Courses and the WestEd Eisenhower Regional Consortium (WERC)

    Science.gov (United States)

    Rognier, E.

    2001-12-01

    The WestEd Eisenhower Regional Consortium (WERC) is in its second year of offering two Earth Systems Science On-line Graduate courses from IGES - one for High School teachers, and one for Middle School teachers. These high-quality courses support WERC's commitment to "supporting increased scientific and mathematical literacy among our nation's youth through services and other support aimed at enhancing the efforts of those who provide K-12 science and mathematics education." WERC has been able to use its EdGateway online community network to offer these courses to environmental education and science teachers nationwide. Through partnerships with the North American Association for Environmental Education (NAAEE), the National Environmental Education Advancement Project (NEEAP), and other regional, state and local science and environmental education organizations, WERC has a broad reach in connecting with science educators nationwide. WERC manages several state and national listservs, which enable us to reach thousands of educators with information about the courses. EdGateway also provides a private online community in which we offer the courses. WERC partners with two Master Teachers from Utah, who facilitate the courses, and with the Center for Science and Mathematics Education at Weber State University, who provides low-cost graduate credit for the courses. Our students have included classroom teachers from upper elementary through high school, community college science teachers, and environmental science center staff who provide inservice for teachers. Educators from Hawaii to New Jersey have provided diverse personal experiences of Earth Systems Science events, and add richness to the online discussions. Two Earth Science Experts, Dr. Rick Ford from Weber State University, and Dr. Art Sussman from WestEd also contribute to the high caliber of learning the students experience in the courses. (Dr. Sussman's book, Dr. Art's Guide to Planet Earth, is used as one of

  2. Profile and outcomes of critically ill children in a lower middle-income country.

    Science.gov (United States)

    Habib, Muhammad Irfan; Khan, Khalid Mehmood A

    2017-07-18

    To determine the clinical profile and outcome of critically ill children presenting to a paediatric ED in a lower middle-income country. We performed a retrospective analysis of children (28 days presenting were malnourished. Interventions included cardiopulmonary resuscitation, application of bubble continuous positive airway pressure and endotracheal intubation. Overall mortality was 13%; 63% of all deaths were in the neonatal age group. Children with the highest triage acuity represent 8% of all visits to a paediatric ED. In this group, neonates account for nearly half of all the children, and more than half of all the deaths among critically ill children came in ED. A large proportion of high-acuity children are malnourished. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  3. Gravitation and quadratic forms

    Science.gov (United States)

    Ananth, Sudarshan; Brink, Lars; Majumdar, Sucheta; Mali, Mahendra; Shah, Nabha

    2017-03-01

    The light-cone Hamiltonians describing both pure ( N = 0) Yang-Mills and N = 4 super Yang-Mills may be expressed as quadratic forms. Here, we show that this feature extends to theories of gravity. We demonstrate how the Hamiltonians of both pure gravity and N = 8 supergravity, in four dimensions, may be written as quadratic forms. We examine the effect of residual reparametrizations on the Hamiltonian and the resulting quadratic form.

  4. Gravitation and quadratic forms

    Energy Technology Data Exchange (ETDEWEB)

    Ananth, Sudarshan [Indian Institute of Science Education and Research,Pune 411008 (India); Brink, Lars [Department of Physics, Chalmers University of Technology,S-41296 Göteborg (Sweden); Institute of Advanced Studies and Department of Physics & Applied Physics,Nanyang Technological University,Singapore 637371 (Singapore); Majumdar, Sucheta [Indian Institute of Science Education and Research,Pune 411008 (India); Mali, Mahendra [School of Physics, Indian Institute of Science Education and Research,Thiruvananthapuram, Trivandrum 695016 (India); Shah, Nabha [Indian Institute of Science Education and Research,Pune 411008 (India)

    2017-03-31

    The light-cone Hamiltonians describing both pure (N=0) Yang-Mills and N=4 super Yang-Mills may be expressed as quadratic forms. Here, we show that this feature extends to theories of gravity. We demonstrate how the Hamiltonians of both pure gravity and N=8 supergravity, in four dimensions, may be written as quadratic forms. We examine the effect of residual reparametrizations on the Hamiltonian and the resulting quadratic form.

  5. Electronic Capitalization Asset Form -

    Data.gov (United States)

    Department of Transportation — National Automated Capitalization Authorization Form used by ATO Engineering Services, Logistics, Accounting for the purpose of identifying and capturing FAA project...

  6. Cooperative Station History Forms

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Various forms, photographs and correspondence documenting the history of Cooperative station instrumentation, location changes, inspections, and...

  7. Do teachers and students get the Ed-Tech products they need: The challenges of Ed-Tech procurement in a rapidly growing market

    Directory of Open Access Journals (Sweden)

    Jennifer Morrison

    2015-03-01

    Full Text Available Ed-tech courseware products to support teaching and learning are being developed and made available for acquisition by school districts at a rapid rate. In this growing market, developers and providers face challenges with making their products visible to customers, while school district stakeholders must grapple with “discovering” which products of the many available best address their instructional needs. The present study presents the experiences with and perceptions about the procurement process from 47 superintendents representing diverse school districts in the U. S. Results indicate that, while improvements are desired in many aspects of the procurement process, the superintendents, overall, believe that, once desired products are identified, they are generally able to acquire them. Difficulties lie in tighter budgets, discovering products that are potentially the best choices, and evaluating the effectiveness of the products selected as options. These findings are presented and interpreted in relation to five major “Action Points” in the procurement process, and also with regard to implications for evaluating how educational technology impacts K-12 instruction.

  8. LUCI ED OMBRE NELL’ATTUAZIONE DEL SISTEMA DI RISOLUZIONE ALTERNATIVA DELLE CONTROVERSIE NEL CONTENZIOSO TRIBUTARIO ITALIANO ED IN QUELLO CROATO

    Directory of Open Access Journals (Sweden)

    Marco Greggi

    2017-01-01

    Full Text Available Nel lavoro gli autori esaminano il sistema della risoluzione alternativa delle controversie (ADR - Alternative Dispute Resolution nelle questioni fi scali in un’ottica comparatistica, ovvero alla luce delle legislazioni e delle dottrine italiana e croata. Nella prima parte del lavoro l’attenzione è rivolta all’esperienza italiana di attuazione del sistema ADR; mentre la seconda parte del lavoro è dedicata all’evoluzione del quadro normativo croato nei tentativi di costruzione di meccanismi di ADR. Il lavoro in entrambe le sue parti contiene una rassegna degli orientamenti dottrinali e attraverso i vari capitoli si sottolinea l’aspetto storico e teorico della questione esaminata. Gli autori dibattono ed espongono sul piano comparatistico anche le implicazioni dell’attuazione del sistema in esame; mentre l’infl uenza della dottrina di diritto pubblico sulla comparsa e lo sviluppo del sistema ADR viene evidenziata mediante l’esposizione della recente prassi italiana e croata del sistema di risoluzione dei contenziosi tributari.

  9. Profiling acute presenting symptoms of geriatric patients attending an urban hospital emergency department.

    Science.gov (United States)

    Foo, Chik Loon; Chan, Kim Chai; Goh, Hsin Kai; Seow, Eillyne

    2009-06-01

    To study the profile of geriatric patients warded to the emergency department (ED) of an Asian acute care general hospital and determine if they are 'more ill', more likely to have atypical presentations and have a higher utilisation of healthcare resources when compared to a younger group of patients. This is a retrospective chart review of consecutive patients aged 45 years and above presenting to the study ED over a period of 4 weeks from 4 June 2006 to 1 July 2006. The following data were obtained: (i) demographics, (ii) mode of arrival and triage acuity, (iii) presence of co-morbidities, (iv) investigations ordered in the ED, (v) clinical symptoms and diagnoses, (vi) disposition, (vii) length of hospital stay, (viii) injuries and outcomes of elderly fallers. The study population was divided into 2 groups--a study group with patients aged 65 years and above, and a control group with patients aged 45 to 64. There were 2847 patients in the study group and these were compared against 2875 in the control group. Those 65 years and above had greater representation in the ED population compared to the general population. In the study group, the proportion of females, the number arriving by ambulance and the likelihood of having a higher triage acuity increased with age. The elderly had higher rates of co-morbidities. They also had a higher resource utilisation rate. Falls was their commonest presenting complaint. It is crucial that EDs recognise the special needs of elderly patients due to the growing ageing population. Healthcare policy makers when allocating resources should take into account the profile of elderly patients presenting to an ED and their resource utilisation.

  10. Isotropy of quadratic forms

    Indian Academy of Sciences (India)

    V. Suresh University Of Hyderabad Hyderabad

    2008-10-31

    Oct 31, 2008 ... Polynomials f (X1,··· ,Xn) − −− polynomial. V. Suresh University Of Hyderabad Hyderabad. Isotropy of quadratic forms ..... Historically, the study of quadratic forms was part of number theory; Minkowski, Siegel, Hasse, Eichler, Kneser and .... For example Z/pZ, p a prime number. V. Suresh University Of ...

  11. Mastering HTML5 forms

    CERN Document Server

    Gupta, Gaurav

    2013-01-01

    This tutorial will show you how to create stylish forms, not only visually appealing, but interactive and customized, in order to gather valuable user inputs and information.Enhance your skills in building responsive and dynamic web forms using HTML5, CSS3, and related technologies. All you need is a basic understanding of HTML and PHP.

  12. PowerForms

    DEFF Research Database (Denmark)

    Brabrand, Claus; Møller, Anders; Ricky, Mikkel

    2000-01-01

    All uses of HTML forms may benefit from validation of the specified input field values. Simple validation matches individual values against specified formats, while more advanced validation may involve interdependencies of form fields. There is currently no standard for specifying or implementing...

  13. Quality assurance in transnational higher education: a case study of the tropEd network.

    Science.gov (United States)

    Zwanikken, Prisca A C; Peterhans, Bernadette; Dardis, Lorraine; Scherpbier, Albert

    2013-03-27

    Transnational or cross-border higher education has rapidly expanded since the 1980s. Together with that expansion issues on quality assurance came to the forefront. This article aims to identify key issues regarding quality assurance of transnational higher education and discusses the quality assurance of the tropEd Network for International Health in Higher Education in relation to these key issues. Literature review and review of documents. From the literature the following key issues regarding transnational quality assurance were identified and explored: comparability of quality assurance frameworks, true collaboration versus erosion of national education sovereignty, accreditation agencies and transparency. The tropEd network developed a transnational quality assurance framework for the network. The network accredits modules through a rigorous process which has been accepted by major stakeholders. This process was a participatory learning process and at the same time the process worked positive for the relations between the institutions. The development of the quality assurance framework and the process provides a potential example for others.

  14. Improving utilization of antimicrobial drugs among physician assistants in the ED.

    Science.gov (United States)

    Kiyatkin, Dmitry E; Wright, Scott; Zenilman, Jonathan; Kisuule, Flora

    2011-10-01

    This study examines the effectiveness of an educational intervention that used audit and feedback to influence physician assistant (PA) antimicrobial utilization in an emergency department (ED). Twelve ED PAs participated in this pre- and postintervention study. Their prescribing patterns were retrospectively reviewed and classified as appropriate, effective but inappropriate, or inappropriate using a previously developed methodology. A hospitalist physician conducted a 1-hour academic detailing intervention session with each PA that reviewed inappropriate prescribing practices and provided feedback for improvement based on current guidelines. After the meetings, the prescribing patterns of the providers were followed prospectively and comparisons were made between the proportions of antimicrobials prescribed appropriately and inappropriately before and after the intervention. The percentage of appropriate prescriptions increased from 64% (95% CI, 58-72) to 81% (95% CI, 75-86), whereas the proportion of inappropriate prescriptions decreased from 36% (95% CI, 31-43) to 19% (95% CI, 14-23) across the study periods (both P < .001). PA antimicrobial utilization was responsive to an academic detailing initiative that relied heavily on audit and feedback of past performance. Targeting PAs in quality improvement initiatives may be a highly effective way to influence change in health care utilization.

  15. Phosphate Reduction in Emulsifi ed Meat Products: Impact of Phosphate Type and Dosage on Quality Characteristics

    Directory of Open Access Journals (Sweden)

    Seline Glorieux

    2017-01-01

    Full Text Available Phosphate reduction is of important industrial relevance in the manufacturing of emulsifi ed meat products because it may give rise to a healthier product. The eff ect of seven diff erent phosphate types was tested on the physicochemical and quality characteristics to select the most promising phosphate type for further cooked sausage manufacturing. Next, phosphate mass fraction was gradually reduced. Tetrasodium di- or pyrophosphate (TSPP and sodium tripolyphosphate (STPP increased pH, reduced structural properties, resulted in the highest emulsion stability, lowest cooking loss and had litt le eff ect on hardness. Based on the viscoelastic properties, a minimum mass fraction of 0.06 % TSPP was suffi cient to obtain an acceptable quality product. Rheology proved to be a very useful tool to evaluate the quality of meat products, as it gives insight in the structure of the meat product and especially the functional properties of meat proteins. Based on the obtained results, it can be concluded that the current amount of phosphate added to emulsifi ed meat products can be signifi cantly reduced with minimal loss of product quality.

  16. Quality assurance in transnational higher education: a case study of the tropEd network

    Science.gov (United States)

    2013-01-01

    Introduction Transnational or cross-border higher education has rapidly expanded since the 1980s. Together with that expansion issues on quality assurance came to the forefront. This article aims to identify key issues regarding quality assurance of transnational higher education and discusses the quality assurance of the tropEd Network for International Health in Higher Education in relation to these key issues. Methods Literature review and review of documents. Results From the literature the following key issues regarding transnational quality assurance were identified and explored: comparability of quality assurance frameworks, true collaboration versus erosion of national education sovereignty, accreditation agencies and transparency. The tropEd network developed a transnational quality assurance framework for the network. The network accredits modules through a rigorous process which has been accepted by major stakeholders. This process was a participatory learning process and at the same time the process worked positive for the relations between the institutions. Discussion The development of the quality assurance framework and the process provides a potential example for others. PMID:23537108

  17. Assessment of environmental enteropathy in the MAL-ED cohort study: theoretical and analytic framework.

    Science.gov (United States)

    Kosek, Margaret; Guerrant, Richard L; Kang, Gagandeep; Bhutta, Zulfiqar; Yori, Pablo Peñataro; Gratz, Jean; Gottlieb, Michael; Lang, Dennis; Lee, Gwenyth; Haque, Rashidul; Mason, Carl J; Ahmed, Tahmeed; Lima, Aldo; Petri, William A; Houpt, Eric; Olortegui, Maribel Paredes; Seidman, Jessica C; Mduma, Estomih; Samie, Amidou; Babji, Sudhir

    2014-11-01

    Individuals in the developing world live in conditions of intense exposure to enteric pathogens due to suboptimal water and sanitation. These environmental conditions lead to alterations in intestinal structure, function, and local and systemic immune activation that are collectively referred to as environmental enteropathy (EE). This condition, although poorly defined, is likely to be exacerbated by undernutrition as well as being responsible for permanent growth deficits acquired in early childhood, vaccine failure, and loss of human potential. This article addresses the underlying theoretical and analytical frameworks informing the methodology proposed by the Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) cohort study to define and quantify the burden of disease caused by EE within a multisite cohort. Additionally, we will discuss efforts to improve, standardize, and harmonize laboratory practices within the MAL-ED Network. These efforts will address current limitations in the understanding of EE and its burden on children in the developing world. © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  18. Voluntary Medication Error Reporting by ED Nurses: Examining the Association With Work Environment and Social Capital.

    Science.gov (United States)

    Farag, Amany; Blegen, Mary; Gedney-Lose, Amalia; Lose, Daniel; Perkhounkova, Yelena

    2017-05-01

    Medication errors are one of the most frequently occurring errors in health care settings. The complexity of the ED work environment places patients at risk for medication errors. Most hospitals rely on nurses' voluntary medication error reporting, but these errors are under-reported. The purpose of this study was to examine the relationship among work environment (nurse manager leadership style and safety climate), social capital (warmth and belonging relationships and organizational trust), and nurses' willingness to report medication errors. A cross-sectional descriptive design using a questionnaire with a convenience sample of emergency nurses was used. Data were analyzed using descriptive, correlation, Mann-Whitney U, and Kruskal-Wallis statistics. A total of 71 emergency nurses were included in the study. Emergency nurses' willingness to report errors decreased as the nurses' years of experience increased (r = -0.25, P = .03). Their willingness to report errors increased when they received more feedback about errors (r = 0.25, P = .03) and when their managers used a transactional leadership style (r = 0.28, P = .01). ED nurse managers can modify their leadership style to encourage error reporting. Timely feedback after an error report is particularly important. Engaging experienced nurses to understand error root causes could increase voluntary error reporting. Published by Elsevier Inc.

  19. Modeling environmental influences on child growth in the MAL-ED cohort study: opportunities and challenges.

    Science.gov (United States)

    Richard, Stephanie A; McCormick, Benjamin J J; Miller, Mark A; Caulfield, Laura E; Checkley, William

    2014-11-01

    Although genetics, maternal undernutrition and low birth weight status certainly play a role in child growth, dietary insufficiency and infectious diseases are key risk factors for linear growth faltering during early childhood. A primary goal of the Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) study is to identify specific risk factors associated with growth faltering during the first 2 years of life; however, growth in early childhood is challenging to characterize because growth may be inherently nonlinear with age. In this manuscript, we describe some methods for analyzing longitudinal growth to evaluate both short- and long-term associations between risk factors and growth trajectories over the first 2 years of life across 8 resource-limited settings using harmonized protocols. We expect there will be enough variability within and between sites in the prevalence of risk factors and burden of linear growth faltering to allow us to distinguish some of the key pathways to linear growth faltering in the MAL-ED study. Published by Oxford University Press on behalf of the Infectious Diseases Society of America 2014. This work is written by (a) US Government employee(s) and is in the public domain in the US.

  20. Laboratory sample turnaround times: do they cause delays in the ED?

    Science.gov (United States)

    Gill, Dipender; Galvin, Sean; Ponsford, Mark; Bruce, David; Reicher, John; Preston, Laura; Bernard, Stephani; Lafferty, Jessica; Robertson, Andrew; Rose-Morris, Anna; Stoneham, Simon; Rieu, Romelie; Pooley, Sophie; Weetch, Alison; McCann, Lloyd

    2012-02-01

    Blood tests are requested for approximately 50% of patients attending the emergency department (ED). The time taken to obtain the results is perceived as a common reason for delay. The objective of this study was therefore to investigate the turnaround time (TAT) for blood results and whether this affects patient length of stay (LOS) and to identify potential areas for improvement. A time-in-motion study was performed at the ED of the John Radcliffe Hospital (JRH), Oxford, UK. The duration of each of the stages leading up to receipt of 101 biochemistry and haematology results was recorded, along with the corresponding patient's LOS. The findings reveal that the mean time for haematology results to become available was 1 hour 6 minutes (95% CI: 29 minutes to 2 hours 13 minutes), while biochemistry samples took 1 hour 42 minutes (95% CI: 1 hour 1 minute to 4 hours 21 minutes), with some positive correlation noted with the patient LOS, but no significant variation between different days or shifts. With the fastest 10% of samples being reported within 35 minutes (haematology) and 1 hour 5 minutes (biochemistry) of request, our study showed that delays can be attributable to laboratory TAT. Given the limited ability to further improve laboratory processes, the solutions to improving TAT need to come from a collaborative and integrated approach that includes strategies before samples reach the laboratory and downstream review of results. © 2010 Blackwell Publishing Ltd.

  1. Mesofauna edáfica: indicador biológico de la calidad del suelo

    Directory of Open Access Journals (Sweden)

    Ana Socarrás

    Full Text Available La búsqueda, el uso y la aplicación de los indicadores de la calidad del suelo se han intensificado en las últimas décadas, debido a la necesidad de preservar este recurso no renovable e indispensable para la vida humana, ante el deterioro creciente. La selección de los indicadores se ha dirigido, fundamentalmente, a conocer el efecto de los usos aplicados y el curso de la rehabilitación de los suelos degradados o contaminados. Los grupos que integran la mesofauna edáfica son sensibles a las perturbaciones naturales y antrópicas del medio, las que provocan cambios en su composición específica y su abundancia, y ocasionan la pérdida de especies y de su diversidad, con la consiguiente disminución de la estabilidad y la fertilidad del suelo. Por ello la mesofauna edáfica es considerada como un buen indicador biológico de su estado de conservación. El número, la densidad y el balance de sus grupos permiten predecir y evaluar las transformaciones ocasionadas por la aplicación de diferentes métodos de producción agrícola en condiciones edafoclimáticas específicas, así como considerar integralmente el funcionamiento del ecosistema.

  2. Optical Klystron Enhancement to Self Amplified Spontaneous Emission at FERMI

    Directory of Open Access Journals (Sweden)

    Giuseppe Penco

    2017-03-01

    Full Text Available The optical klystron enhancement to a self-amplified spontaneous emission free electron laser has been studied in theory and in simulations and has been experimentally demonstrated on a single-pass high-gain free electron laser, the FERMI FEL-1, in 2014. The main concept consists of two undulators separated by a dispersive section that converts the energy modulation induced in the first undulator in density modulation, enhancing the coherent harmonic generation in the first part of the second undulator. This scheme could be replicated in a multi-stage: the bunching is enhanced after each dispersive section, consistently reducing the saturation length. We have applied the multi-stage optical klystron (OK scheme on the FEL-2 line at FERMI, whose layout includes three dispersive sections. Optimizing the strength of the dispersions allowed a significant increase of the self-amplified spontaneous emission (SASE intensity in comparison to a single-stage OK and extending to the soft-X rays the OK enhanced SASE previously demonstrated on FEL-1.

  3. Evaluating the Value of High Spatial Resolution in National Capacity Expansion Models using ReEDS

    Energy Technology Data Exchange (ETDEWEB)

    Krishnan, Venkat; Cole, Wesley

    2016-07-18

    This poster is based on the paper of the same name, presented at the IEEE Power & Energy Society General Meeting, July18, 2016. Power sector capacity expansion models (CEMs) have a broad range of spatial resolutions. This paper uses the Regional Energy Deployment System (ReEDS) model, a long-term national scale electric sector CEM, to evaluate the value of high spatial resolution for CEMs. ReEDS models the United States with 134 load balancing areas (BAs) and captures the variability in existing generation parameters, future technology costs, performance, and resource availability using very high spatial resolution data, especially for wind and solar modeled at 356 resource regions. In this paper we perform planning studies at three different spatial resolutions - native resolution (134 BAs), state-level, and NERC region level - and evaluate how results change under different levels of spatial aggregation in terms of renewable capacity deployment and location, associated transmission builds, and system costs. The results are used to ascertain the value of high geographically resolved models in terms of their impact on relative competitiveness among renewable energy resources.

  4. Evaluation and development of an ED management model: an effort to optimize patient-centered care.

    Science.gov (United States)

    McDonough, Kelly S; Pemberton, Meg

    2013-09-01

    In 2008, the emergency department at Mary Washington Hospital was in the midst of a crisis marked by increasing volumes, increasing numbers of left without being seen (LWBS) patients, falling patient satisfaction numbers and a staff dissatisfied with ED leadership. The existing ED model of charge nurses, a nurse manager, and an administrative director was not working. The single nurse manager could not effectively manage the over 200 staff members he/she was assigned. Based upon the findings from the employee satisfaction survey the inability of the nurse managers to properly manage such large numbers of employees was at the core of the issue. Through benchmarking with a similar healthcare system, an evidence based leadership model was identified, developed, and implemented. The model included the addition of six patient care managers with 24-hour coverage in the department, led to a reduced number of direct reports per manager, and an increased connection with employees. The goal was to engage employees in the effort to provide patient centered, quality care. Residual benefits of our change effort improved the patient satisfaction scores as evidenced by meeting organizational goals within 12 months; goal was exceeded in the following year. Additionally, the walk out rate was reduced 75% over 18 months. The correlation between satisfied employees, patient satisfaction, and reduced walk-outs cannot be ignored. Engaged employees positively impact service and quality. Copyright © 2013 Emergency Nurses Association. Published by Mosby, Inc. All rights reserved.

  5. Evaluation of acid-base status in patients admitted to ED-physicochemical vs traditional approaches.

    Science.gov (United States)

    Antonogiannaki, Elvira-Markela; Mitrouska, Ioanna; Amargianitakis, Vassilis; Georgopoulos, Dimitris

    2015-03-01

    The aim of this study is to evaluate the value of physicochemical, base excess (BE), and plasma bicarbonate concentration ([HCO3(-)]) approaches on the assessment of acid-base status in patients presented to the emergency department (ED). Upon presentation at ED, patients whose arterial blood was deemed in need of analysis were studied. Arterial blood gases, serum electrolytes, and proteins were measured and used to derive [HCO3(-)], BE, anion gap (AG), AG adjusted for albumin (AGadj), strong ion difference, strong ion gap (SIG) and SIG corrected for water excess/deficit (SIGcor). In each patient the acid-base status was evaluated using the BE, [HCO3(-)], and physicochemical approaches. A total of 365 patients were studied. Compared with BE (n = 202) and [HCO3(-)] (n = 151), physicochemical approach (n = 279) identified significantly more patients with metabolic acid-base disturbances (P physicochemical approach. The corresponding values with [HCO3(-)] approach were 108 and 95 (88%) patients. When patients with high AGadj were excluded, 44 patients with BE and 67 with [HCO3(-)] approach had normal acid-base status, and most of them exhibited at least 1 acid-base disturbance with the physicochemical approach, whereas 12 and 21 patients, respectively, had high SIGcor. Compared with the BE and [HCO3(-)] methods, the physicochemical approach has a better diagnostic accuracy to identify metabolic acid-base disturbances. Copyright © 2014 Elsevier Inc. All rights reserved.

  6. Pilot study of Myers Briggs Type Indicator personality profiling in emergency department senior medical staff.

    Science.gov (United States)

    Boyd, Russell; Brown, Terry

    2005-06-01

    To study the viability of using the Myers Briggs Type Indicator (MBTI) in senior ED medical staff and to examine what trends, if any, in personality types exist within the specialty. A pilot cross-sectional survey was undertaken during which a standard MBTI questionnaire was sent anonymously to a convenience sample of senior ED medical staff in Tasmania and South Australia. Completed surveys after a second mailing were analysed and the results collated. Of 82 senior ED medical staff surveyed, 68 returned completed questionnaires (response rate 83%). The single most common personality group in the cohort was the (Extrovert/Intuitive/Thinking/Judging) ENTJ type exhibited by 12 (17.7%, 95% CI 9.4-28.7%) clinicians in the cohort. This group is present at a rate of 3% in the general population. In terms of individual traits, Introversion was exhibited by 33 (48.5%, 95% CI 36.2-61%), Intuitive traits by 40 (58.8%, 95% CI 46.2-70.6%), Thinking traits by 40 (58.8%, 95% CI 46.2-70.6%) and Judging traits by 53 (77.9%, 95% CI 66.2-87.1%) of our cohort of senior ED medical staff. Our senior ED medical staff cohort suggests notable variations from the general population in terms of their MBTI profiles.

  7. GLL RPT IONOSPHERE PROFILES

    Data.gov (United States)

    National Aeronautics and Space Administration — The Galileo Radio Propagation Team Ionosphere Profile data set is small number of electron density profiles derived from radio occultation data collected while...

  8. GHGRP Industrial Profiles

    Science.gov (United States)

    EPA's Greenhouse Gas Reporting Program periodically produces detailed profiles of the various industries that report under the program. These profiles contain detailed analyses. This page hosts data highlights for all sectors.

  9. HOPWA Performance Profiles

    Data.gov (United States)

    Department of Housing and Urban Development — HOPWA Performance Profiles are generated quarterly for all agencies receiving HOPWA formula or competitive grants. Performance Profiles are available at the national...

  10. Transmission electron microscopy analysis of corroded metal waste forms.

    Energy Technology Data Exchange (ETDEWEB)

    Dietz, N. L.

    2005-04-15

    This report documents the results of analyses with transmission electron microscopy (TEM) combined with energy dispersive X-ray spectroscopy (EDS) and selected area electron diffraction (ED) of samples of metallic waste form (MWF) materials that had been subjected to various corrosion tests. The objective of the TEM analyses was to characterize the composition and microstructure of surface alteration products which, when combined with other test results, can be used to determine the matrix corrosion mechanism. The examination of test samples generated over several years has resulted in refinements to the TEM sample preparation methods developed to preserve the orientation of surface alteration layers and the underlying base metal. The preservation of microstructural spatial relationships provides valuable insight for determining the matrix corrosion mechanism and for developing models to calculate radionuclide release in repository performance models. The TEM results presented in this report show that oxide layers are formed over the exposed steel and intermetallic phases of the MWF during corrosion in aqueous solutions and humid air at elevated temperatures. An amorphous non-stoichiometric ZrO{sub 2} layer forms at the exposed surfaces of the intermetallic phases, and several nonstoichiometric Fe-O layers form over the steel phases in the MWF. These oxide layers adhere strongly to the underlying metal, and may be overlain by one or more crystalline Fe-O phases that probably precipitated from solution. The layer compositions are consistent with a corrosion mechanism of oxidative dissolution of the steel and intermetallic phases. The layers formed on the steel and intermetallic phases form a continuous layer over the exposed waste form, although vertical splits in the layer and corrosion in pits and crevices were seen in some samples. Additional tests and analyses are needed to verify that these layers passivate the underlying metals and if passivation can break

  11. ANALYSIS OF FORMING TREAD WHEEL SETS

    Directory of Open Access Journals (Sweden)

    Igor IVANOV

    2017-09-01

    Full Text Available This paper shows the results of a theoretical study of profile high-speed grinding (PHSG for forming tread wheel sets during repair instead of turning and mold-milling. Significant disadvantages of these methods are low capacity to adapt to the tool and inhomogeneous structure of the wheel material. This leads to understated treatment regimens and difficulties in recovering wheel sets with thermal and mechanical defects. This study carried out modeling and analysis of emerging cutting forces. Proposed algorithms describe the random occurrence of the components of the cutting forces in the restoration profile of wheel sets with an inhomogeneous structure of the material. To identify the statistical features of randomly generated structures fractal dimension and the method of random additions were used. The multifractal spectrum formed is decomposed into monofractals by wavelet transform. The proposed method allows you to create the preconditions for controlling the parameters of the treatment process.

  12. Dispositivi formativi e forme di vita

    Directory of Open Access Journals (Sweden)

    Francesco Cappa

    2016-02-01

    Full Text Available Il dibattito pedagogico che ha caratterizzato gli ultimi anni ha spesso insistito sull’importanza del nesso tra sviluppo tecnologico e modelli formativi. Questa relazione, però, troppo spesso non valorizza i modi in cui l’esperienza educativa e formativa dovrebbe essere sempre più accuratamente pensata, progettata e predisposta se vista dalla prospettiva delle buone pratiche tecnologiche. Tale valorizzazione dell’istanza formativa deve prendere avvio da una riflessione critica e approfondita sui modelli impliciti ed espliciti che caratterizzano le pratiche educative e formative, valorizzando l’uso e l’interpretazione che i soggetti rendono attuali.Per consentire tale riflessione è necessario pensare un dispositivo pedagogico che non perda di vista la complessità delle dimensioni che agiscono nell’accadere educativo, capace di creare nuovi percorsi di sperimentazione delle conoscenze e nuove ipotesi di formazione di sé e degli altri. La formazione interpretata alla luce dei dispositivi pedagogici può offrire un valido strumento teorico e pratico per immaginare, progettare e valutare gli effetti che ogni azione formativa produce legati alla trasformazione dei saperi, alla vita delle forme e alle forme di vita contemporanee.

  13. PROFILER: 1D galaxy light profile decomposition

    Science.gov (United States)

    Ciambur, Bogdan C.

    2017-05-01

    Written in Python, PROFILER analyzes the radial surface brightness profiles of galaxies. It accurately models a wide range of galaxies and galaxy components, such as elliptical galaxies, the bulges of spiral and lenticular galaxies, nuclear sources, discs, bars, rings, and spiral arms with a variety of parametric functions routinely employed in the field (Sérsic, core-Sérsic, exponential, Gaussian, Moffat and Ferrers). In addition, Profiler can employ the broken exponential model (relevant for disc truncations or antitruncations) and two special cases of the edge-on disc model: namely along the major axis (in the disc plane) and along the minor axis (perpendicular to the disc plane).

  14. Impact of a bronchiolitis guideline on ED resource use and cost: a segmented time-series analysis.

    Science.gov (United States)

    Akenroye, Ayobami T; Baskin, Marc N; Samnaliev, Mihail; Stack, Anne M

    2014-01-01

    Bronchiolitis is a major cause of infant morbidity and contributes to millions of dollars in health care costs. Care guidelines may cut costs by reducing unnecessary resource utilization. Through the implementation of a guideline, we sought to reduce unnecessary resource utilization and improve the value of care provided to infants with bronchiolitis in a pediatric emergency department (ED). We conducted an interrupted time series that examined ED visits of 2929 patients with bronchiolitis, aged 1 to 12 months old, seen between November 2007 and April 2013. Outcomes were proportion having a chest radiograph (CXR), respiratory syncytial virus (RSV) testing, albuterol or antibiotic administration, and the total cost of care. Balancing measures included admission rate, returns to the ED resulting in admission within 72 hours of discharge, and ED length of stay (LOS). There were no significant preexisting trends in the outcomes. After guideline implementation, there was an absolute reduction of 23% in CXR (95% confidence interval [CI]: 11% to 34%), 11% in RSV testing (95% CI: 6% to 17%), 7% in albuterol use (95% CI: 0.2% to 13%), and 41 minutes in ED LOS (95% CI: 16 to 65 minutes). Mean cost per patient was reduced by $197 (95% CI: $136 to $259). Total cost savings was $196,409 (95% CI: $135,592 to $258,223) over the 2 bronchiolitis seasons after guideline implementation. There were no significant differences in antibiotic use, admission rates, or returns resulting in admission within 72 hours of discharge. A bronchiolitis guideline was associated with reductions in CXR, RSV testing, albuterol use, ED LOS, and total costs in a pediatric ED.

  15. Use of a midstream clean catch mobile application did not lower urine contamination rates in an ED.

    Science.gov (United States)

    Jacob, Mary S; Kulie, Paige; Benedict, Cameron; Ordoobadi, Alexander J; Sikka, Neal; Steinmetz, Erika; McCarthy, Melissa L

    2018-01-01

    Urine microscopy is a common test performed in emergency departments (EDs). Urine specimens can easily become contaminated by different factors, including the collection method. The midstream clean-catch (MSCC) collection technique is commonly used to reduce urine contamination. The urine culture contamination rate from specimens collected in our ED is 30%. We developed an instructional application (app) to show ED patients how to provide a MSCC urine sample. We hypothesized that ED patients who viewed our instructional app would have significantly lower urine contamination rates compared to patients who did not. We prospectively enrolled 257 subjects with a urinalysis and/or urine culture test ordered in the ED and asked them to watch our MSCC instructional app. After prospective enrollment was complete, we retrospectively matched each enrolled subject to an ED patient who did not watch the instructional app. Controls were matched to cases based on gender, type of urine specimen provided, ED visit date and shift. Urinalysis and urine culture contamination results were compared between the matched pairs using McNemar's test. The overall urine culture contamination rate of the 514 subjects was 38%. The majority of the matched pairs had a urinalysis (63%) or urinalysis plus urine culture (35%) test done. There were no significant differences in our urine contamination rates between the matched pairs overall or when stratified by gender, by prior knowledge of the clean catch process or by type of urine specimen. We did not see a lower contamination rate for patients who viewed our instructional app compared to patients who did not. It is possible that MSCC is not effective for decreasing urine specimen contamination. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. Should we fear "flu fear" itself? Effects of H1N1 influenza fear on ED use.

    Science.gov (United States)

    McDonnell, William M; Nelson, Douglas S; Schunk, Jeff E

    2012-02-01

    Surges in patient volumes compromise emergency departments' (EDs') ability to deliver care, as shown by the recent H1N1 influenza (flu) epidemic. Media reports are important in informing the public about health threats, but the effects of media-induced anxiety on ED volumes are unclear. The aim of this study is to examine the effect of widespread public concern about flu on ED use. We reviewed ED data from an integrated health system operating 18 hospital EDs. We compared ED visits during three 1-week periods: (a) a period of heightened public concern regarding flu before the disease was present ("Fear Week"), (b) a subsequent period of active disease ("Flu Week"), and (c) a week before widespread concern ("Control Week"). Fear Week was identified from an analysis of statewide Google electronic searches for "swine flu" and from media announcements about flu. Flu Week was identified from statewide epidemiological data. Data were reviewed from 22 608 visits during the study periods. Fear Week (n = 7712) and Flu Week (n = 7687) were compared to Control Week (n = 7209). Fear Week showed a 7.0% increase in visits (95% confidence interval, 6-8). Pediatric visits increased by 19.7%, whereas adult visits increased by 1%. Flu Week showed an increase over Control Week of 6.6% (95% confidence interval, 6-7). Pediatric visits increased by 10.6%, whereas adult visits increased by 4.8%. At a time of heightened public concern regarding flu but little disease prevalence, EDs experienced substantial increases in patient volumes. These increases were significant and comparable to the increases experienced during the subsequent epidemic of actual disease. Copyright © 2012 Elsevier Inc. All rights reserved.

  17. NOAA Form 370 Database

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data set contains information from submitted NOAA Form 370s, also known as the Fisheries Certificate of Origin, for imported shipments of frozen and/or processed...

  18. Forms of Dystonia

    Science.gov (United States)

    ... Fellowship Training Program Dystonia Coalition Dystonia Study Group Global Dystonia Registry About Us Mission & History How Will We Find a Cure? People Newsletters & Press Releases Dystonia Dialogue Financials Contact What is Dystonia? Symptoms & Diagnosis Forms ...

  19. VMS forms Output Tables

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These output tables contain parsed and format validated data from the various VMS forms that are sent from any given vessel, while at sea, from the VMS devices on...

  20. Forms of global governence

    Directory of Open Access Journals (Sweden)

    Maxim V. Kharkevich

    2014-01-01

    Full Text Available Global governance as a concept defines the meaning of contemporary world politics both as a discipline and as reality. Interdependent and globalized world requires governance, and a global government has not been formed yet. The theoretical possibility of global governance without global government is proved and justified. The purpose of this article is to analytically identify possible forms of global governance. Three such forms of global governance are identified: hierarchical, market and network. In a hierarchy the governance is due to the asymmetry of power between the parties. Market control happens via anonymous pricing mechanism. Network, in contrast to the market is characterized by a closer value link between the actors, but unlike the hierarchical relationship actors are free to leave the network. Global governance takes three forms and is being implemented by different actors. To determine the most efficient form of global governance is impossible. Efficiency depends on the match between a form and an object of government. It should be noted that meta governance is likely to remain a monopoly of institutionally strong states in global governance.

  1. Improving predictions of carbon fluxes in the tropics undre climatic changes using ED2

    Science.gov (United States)

    Feng, X.; Uriarte, M.

    2016-12-01

    Tropical forests play a critical role in the exchange of carbon between land and atmosphere, highlighting the urgency of understanding the effects of climate change on these ecosystems. The most optimistic predictions of climate models indicate that global mean temperatures will increase by up to 2 0C with some tropical regions experiencing extreme heat. Drought and heat-induced tree mortality will accelerate the release of carbon to the atmosphere creating a positive feedback that greatly exacerbates global warming. Thus, under a warmer and drier climate, tropical forests may become net sources, rather than sinks, of carbon. Earth system models have not reached a consensus on the magnitude and direction of climate change impacts on tropical forests, calling into question the reliability of their predictions. Thus, there is an immediate need to improve the representation of tropical forests in earth system models to make robust predictions. The goal of our study is to quantify the responses of tropical forests to climate variability and improve the predictive capacity of terrestrial ecosystem models. We have collected species-specific physiological and functional trait data from 144 tree species in a Puerto Rican rainforest to parameterize the Ecosystem Demography model (ED2). The large amount of data generated by this research will lead to better validation and lowering the uncertainty in future model predictions. To best represent the forest landscape in ED2, all the trees have been assigned to three plant functional types (PFTs): early, mid, and late successional species. Trait data for each PFT were synthesized in a Bayesian meta-analytical model and posterior distributions of traits were used to parameterize the ED2 model. Model predictions show that biomass production of late successional PFT (118.89 ton/ha) was consistently higher than mid (71.33 ton/ha) and early (13.21 ton/ha) PFTs. However, mid successional PFT had the highest contributions to NPP for the

  2. Early primary care follow-up after ED and hospital discharge - does it affect readmissions?

    Science.gov (United States)

    Sinha, Sanjai; Seirup, Joanna; Carmel, Amanda

    2017-04-01

    After hospitalization, timely discharge follow-up has been linked to reduced readmissions in the heart failure population, but data from general inpatients has been mixed. The objective of this study was to determine if there was an association between completed follow-up appointments within 14 days of hospital discharge and 30-day readmission amongst primary care patients at an urban academic medical center. Index discharges included both inpatient and emergency room settings. A secondary objective was to identify patient factors associated with completed follow-up appointments within 14 days. We conducted a retrospective review of primary care patients at an urban academic medical center who were discharged from either the emergency department (ED) or inpatient services at the Weill Cornell Medical Center/New York Presbyterian Hospital from 1 January 2014-31 December 2014. Cox proportional hazard models were used to identify the relationship between follow-up in primary care within 14 days and readmission within 30 days. Logistic regression was used to evaluate the association of patient factors with 14-day follow-up. Among 9,662 inpatient and ED discharges, multivariable analysis (adjusting for age, gender, race/ethnicity, insurance, number of diagnoses on problem list, length of stay, and discharge service) showed that follow-up with primary care within 14 days was not associated with a lower hazard of readmission within 30 days (HR = 0.78; 95% CI 0.56-1.09). A higher number of diagnoses on the problem list was associated with greater odds of follow-up for both inpatient and emergency department discharges (inpatient: HR = 1.03, 95% CI 1.02-1.04; ED: HR = 1.02, 95% CI 1.00-1.04). For inpatient discharges, each additional day in length of stay was associated with 3% lower odds of follow-up (HR = 0.97, 95% CI 0.96-0.99). Early follow-up within 14 days after discharge from general inpatient services was associated with a trend toward lower hazard of

  3. Dynamic evapotranspiration in tree-resolving LES - The ED2RAFLES model

    Science.gov (United States)

    Bohrer, G.; Medvigy, D.

    2010-12-01

    How evapotranspiration scales from individual plants to a landscape is a critical problem in hydrology. To investigate this problem, we developed a version of the RAMS-Based Forest Large Eddy Simulations (RAFLES) which includes a dynamic, multi-layered evapotranspiration and CO2 uptake. RAFLES resolves vegetation as a heterogeneous 3D field. It can run at resolutions down to 1 m^3 and can incorporate explicit canopy representations derived from lidar. The canopy influences dynamics through a drag term, proportional to the leaf density at each numerical cell, and as a solid volume, which blocks some of the volume and apertures inside the canopy space. To calculate the exchange of scalar fluxes between the canopy and the air, the Ecosystem Demography version 2 (ED2) was coupled with RAFLES. ED2RAFLES dynamically resolves sensible heat fluxes, evapotranspiration, radiative transfer, and carbon fluxes. The surface energy budget is solved at vertical levels inside the canopy to find the skin temperature of the leaves and soil surface, and evapotranspiration rates. Evapotranspiration is also driven by frictional velocity near the leaves and is further restricted by stomatal conductance, parameterized using a Ball-Berry scheme, and by soil water availability. We tested the sensitivity of modeled evapotranspiration to the dynamic representation for a virtual canopy domain, based on the spatial structure of the forest around the Ameriflux eddy-flux tower, at the University of Michigan Biological Station (UMBS). A “test” simulation used the dynamic ED2-driven evaporation. A “control” simulation prescribed sensible and latent heat fluxes as a function of LAI and light attenuation at a rate equal to the mean heat flux from the test simulation. The simulation differed in the degree of spatial heterogeneity of fluxes across the domains and in the coherency between canopy structure and evaporation. Quantifying this coherency is important to our understanding of the

  4. Management of ED under the "severe distress" criteria in the NHS: a real-life study.

    Science.gov (United States)

    Mohee, Amar; Bretsztajn, Laure; Storey, Anne; Eardley, Ian

    2014-04-01

    The United Kingdom is unusual in that a significant proportion of patients with erectile dysfunction (ED) have their treatment fully reimbursed by the National Health Service (NHS). This may have consequences for the choice of treatment and for compliance with treatment. The aim of this study was to evaluate the use and cost implications of phosphodiesterase type 5 inhibitor in an NHS setting. Basic demographics and data on ED management for patients treated from January 2000 to April 2011 were obtained from a prospectively accrued database. We reviewed drug usage and costs as well as switching between drugs. Patients were given the choice of all available therapies and were followed up annually. Switching, compliance, and costs of treating ED under the "severe distress" criteria in the NHS were reviewed for this study. Two thousand one hundred fifty-nine patients qualified for reimbursed therapy. Two hundred twenty-six patients were excluded from further analysis owing to missing data. Patients were followed up on an annual basis. The mean patient age was 60.2 years (min 23, max 90), and the mean follow-up was 50.8 months (min 1, max 127). Six hundred ninety-six were started on sildenafil, 990 on tadalafil, 163 on vardenafil, and 84 on intracavernosal alprostadil. Eighteen percent of patients initially started on the scheme and stopped medication unilaterally. Of the patients, 12.3% changed their medication during follow-up. The cost of drugs increased year by year from £257,100 in 2007 to £352,519 in 2011. Our real-life observational study shows that in our institution, dropout of therapy is unusual. We hypothesize that this reflects, in part, the reimbursement issue. We also found that switching between drugs was unusual, although there are several possible explanations for that. Although this is a successful system for the patients, the hospital, which bears the costs of medication, is finding this an increasing economic drain. © 2014 International Society

  5. Characteristics of metal waste forms containing technetium and uranium

    Energy Technology Data Exchange (ETDEWEB)

    Fortner, J.A.; Kropf, A.J.; Ebert, W.L. [Argonne National Laboratory, Argonne, IL 60439 (United States)

    2013-07-01

    2 prototype alloys: RAW-1(Tc) and RAW-2(UTc) suitable for a wide range of waste stream compositions are being evaluated to support development of a waste form degradation model that can be used to calculate radionuclide source terms for a range of waste form compositions and disposal environments. Tests and analyses to support formulation of waste forms and development of the degradation model include detailed characterizations of the constituent phases using SEM/EDS and TEM, electrochemical tests to quantify the oxidation behavior and kinetics of the individual and coupled phases under a wide range of environmental conditions, and corrosion tests to measure the gross release kinetics of radionuclides under aggressive test conditions.

  6. Avaliação da fadiga e da secura na síndrome de Sjögren primária: versão brasileira do “Profile of Fatigue and Discomfort – Sicca Symptoms Inventory (short form (Profad-SSI-SF”

    Directory of Open Access Journals (Sweden)

    Samira Tatiyama Miyamoto

    2015-04-01

    Full Text Available Objetivo: Fazer a adaptação transcultural e a validação do Profile of Fatigue and Discomfort – Sicca Symptoms Inventory (short form (Profad-SSI-SF, questionário que avalia os aspectos subjetivos dos sintomas da síndrome de Sjögren primária (SSp, para a língua portuguesa brasileira. Método: Foi avaliada a equivalência conceitual, de item, semântica e operacional. A versão brasileira do Profad-SSI-SF foi aplicada a 62 mulheres com SSp conforme consenso europeu-americano de 2002 para avaliar a equivalência de mensuração. Foi usado o α-Cronbach para consistência interna; coeficiente de correlação intraclasse (ICC para reprodutibilidade intraobservador; e coeficiente de correlação de Spearman para validade em comparação com o Patient Global Assessment (PaGA, Eular Sjögren’s Syndrome Patient Reported Index (ESS-PRI, Functional Assessment of Chronic Illness Therapy Fatigue Subscale (Facit-F e EuroQOL(EQ-5D. Resultados: A consistência interna do Profad, do SSI e da pontuação total foi de 0,80, 0,78 e 0,87, respectivamente. A reprodutibilidade intraobservador do Profad total foi de 0,89; do SSI total de 0,86 e da pontuação total de 0,89. Na validade, o Profad apresentou correlação significativa com o PaGA (r = 0,50, Facit-F (r = 0,59, Esspri (r = 0,58 e todos os domínios do EQ-5D, com exceção da mobilidade. Já o SSI apresentou correlação significativa com o PaGA (r = 0,43, Facit-F (r = 0,57, Esspri (r = 0,55 e a maioria dos domínios do EQ-5D. A pontuação total do Profad-SSI-SF só não obteve correlação estatisticamente significante com o domínio mobilidade e escala 1 a 100 do EQ-D5.

  7. Development of a Climatology of Vertically Complete Wind Profiles from Doppler Radar Wind Profiler Systems

    Science.gov (United States)

    Barbre, Robert E., Jr.

    2015-01-01

    This paper describes in detail the QC and splicing methodology for KSC's 50- and 915-MHz DRWP measurements that generates an extensive archive of vertically complete profiles from 0.20-18.45 km. The concurrent POR from each archive extends from April 2000 to December 2009. MSFC NE applies separate but similar QC processes to each of the 50- and 915-MHz DRWP archives. DRWP literature and data examination provide the basis for developing and applying the automated and manual QC processes on both archives. Depending on the month, the QC'ed 50- and 915-MHz DRWP archives retain 52-65% and 16-30% of the possible data, respectively. The 50- and 915-MHz DRWP QC archives retain 84-91% and 85-95%, respectively, of all the available data provided that data exist in the non- QC'ed archives. Next, MSFC NE applies an algorithm to splice concurrent measurements from both DRWP sources. Last, MSFC NE generates a composite profile from the (up to) five available spliced profiles to effectively characterize boundary layer winds and to utilize all possible 915-MHz DRWP measurements at each timestamp. During a given month, roughly 23,000-32,000 complete profiles exist from 0.25-18.45 km from the composite profiles' archive, and approximately 5,000- 27,000 complete profiles exist from an archive utilizing an individual 915-MHz DRWP. One can extract a variety of profile combinations (pairs, triplets, etc.) from this sample for a given application. The sample of vertically complete DRWP wind measurements not only gives launch vehicle customers greater confidence in loads and trajectory assessments versus using balloon output, but also provides flexibility to simulate different DOL situations across applicable altitudes. In addition to increasing sample size and providing more flexibility for DOL simulations in the vehicle design phase, the spliced DRWP database provides any upcoming launch vehicle program with the capability to utilize DRWP profiles on DOL to compute vehicle steering

  8. WDS versus silicon drift detector EDS: a case report for the comparison of quantitative chemical analyses of natural silicate minerals.

    Science.gov (United States)

    Cubukçu, H Evren; Ersoy, Orkun; Aydar, Erkan; Cakir, Uner

    2008-01-01

    Electron probe microanalysis (EPMA) is an essential analytical approach to determine elemental concentrations of various solid specimens quantitatively in mineralogical, petrological and materials research. Either wavelength dispersive X-ray (WDS) or energy dispersive X-ray (EDS) spectrometric techniques can collect the characteristic X-rays generated from each element in the specimen by an incident electron beam in order to define chemical constituents. Although WDS has been the preferred technique because of its higher spectral resolution and ability to detect trace elements, new generation EDS systems with silicon drift detectors (SDD), equipped with thin windows and integrated digital processing electronics, are claimed to approach the WDS throughput. In this study, we compared the analytical capability of a SDD EDS system with respect to WDS equipped systems on natural silicate minerals. For this purpose, natural rock samples, in which the silicate minerals present had already been analysed by various WDS systems, were chosen to compare these results with the ones acquired with a SDD EDS system. SDD EDS yielded satisfactory results for major elements (Na, Mg, Al, Si, K, Ca, Ti, Mn and Fe) compared with the results of the same minerals obtained by various WDS systems.

  9. Reliability and validity of the Conditional Goal Setting in Eating Disorders Scale (CGS-EDS) among adults with eating disorders.

    Science.gov (United States)

    Watson, Hunna J; Street, Helen; Raykos, Bronwyn C; Byrne, Susan M; Fursland, Anthea; Nathan, Paula R

    2010-04-01

    The aim of this study was to develop and validate a self-report measure of Conditional Goal Setting (CGS) for use among individuals with eating disorders, the Conditional Goal Setting in Eating Disorders Scale (CGS-EDS). The CGS-EDS assesses the degree to which an individual believes that the achievement of happiness is contingent upon the attainment of body shape and weight goals. Women with a DSM-IV diagnosed eating disorder consecutively referred to a specialist outpatient clinic (N=238) completed the CGS-EDS and self-report measures of theoretically related constructs. Exploratory factor analysis indicated a one-factor solution, which accounted for 65% of the variance. The CGS-EDS correlated positively with theoretically related measures of overvaluation of shape and weight, concern with shape and weight, dichotomous thinking, and depression. The alpha reliability of the scale was .92. The CGS-EDS is a valid and reliable measure of CGS in eating disorders and is relevant to cognitive and behavioral models of maintenance and intervention. Copyright 2009 Elsevier Ltd. All rights reserved.

  10. HARDNESS INDICES ESTIMATION OF SUPPORTING STRUCTURE ELEMENTS OF MOTOR BOGIES OF THE ELECTRIC TRAIN ED9M

    Directory of Open Access Journals (Sweden)

    O. M. Bondarev

    2013-08-01

    Full Text Available Purpose. The purpose of article is to develop the measures of hardness indices improvement of the supporting structures of motor cars of the electric trains ED9M. Methodology. In order to achieve the above stated aims the following measures had to be done: to develop a finite element model of the supporting structures of the motor bogie of the electric train ED9M, determine parameters of the developed model; perform the calculations to determine the stress-strain state during loads corresponding to different operating conditions with the search of geometric parameters reducing the highest stress levels. Findings. The obtained results of calculations (fields of stress distribution and strains in the elements of the motor bogie frame from the viewpoint of the strength and stiffness discovered the best geometric parameters of the bearings in the central suspension beams of the electric trains ED9M in the places of load transmission from the car body to the bogie frame. Originality. Based on the developed finite element models and the theoretical and experimental researches the scientifically grounded modernization measures of the construction elements of the central suspension beams for motor bogies of the electric trains ED9M were developed. Practical value. It was developed an engineering solution concerning the measures to improve the strength and stiffness characteristics of the central suspension beams for the motor cars of the electric trains ED9M. It was given to the Ukrzaliznytsya’s professionals to implement them during repairs.

  11. The HEADS-ED: a rapid mental health screening tool for pediatric patients in the emergency department.

    Science.gov (United States)

    Cappelli, Mario; Gray, Clare; Zemek, Roger; Cloutier, Paula; Kennedy, Allison; Glennie, Elizabeth; Doucet, Guy; Lyons, John S

    2012-08-01

    The American Academy of Pediatrics called for action for improved screening of mental health issues in the emergency department (ED). We developed the rapid screening tool home, education, activities/peers, drugs/alcohol, suicidality, emotions/behavior, discharge resources (HEADS-ED), which is a modification of "HEADS," a mnemonic widely used to obtain a psychosocial history in adolescents. The reliability and validity of the tool and its potential for use as a screening measure are presented. ED patients presenting with mental health concerns from March 1 to May 30, 2011 were included. Crisis intervention workers completed the HEADS-ED and the Child and Adolescent Needs and Strengths-Mental Health tool (CANS MH) and patients completed the Children's Depression Inventory (CDI). Interrater reliability was assessed by using a second HEADS-ED rater for 20% of the sample. A total of 313 patients were included, mean age was 14.3 (SD 2.63), and there were 182 females (58.1%). Interrater reliability was 0.785 (P mental health concerns.

  12. Origine ed evoluzione dell'universo dal big-bang alle galassie

    CERN Document Server

    Gratton, Livio

    1992-01-01

    Il volume, destinato a un vasto pubblico di lettori anche non particolarmente versati in materie scientifiche, offre un panorama aggiornato e completo degli sviluppi più recenti della cosmologia, la scienza che studia l'Universo nel suo complesso. Abbandonate ormai completamente visioni mitiche e geocentriche, la moderna cosmologia ripresenta come un ambizioso e affascinante tentativo di creare un modello unitario dell'Universo e della sua evoluzione attraverso gli strumenti della fisica e dell'astronomia. In questo quadro, nato da una profonda riflessione sui concetti di spazio e di tempo sviluppatasi nei primi decenni del secolo soprattutto da parte di Einstein, e sostenuto dal prodigioso progresso della tecnologia che ha aperto nuove e rivoluzionarie possibilità di osservazione, un succedersi sempre più incalzante ed emozionante di scoperte sta rivelando un panorama inaspettatamente vario, complesso, e allo stesso tempo semplice e unitario, la cui interpretazione richiede al cosmologo rigore, fantasia e...

  13. PENGENDALIAN MESIN HOIST HANGER DALAM PROSES PTC/ED MENGGUNAKAN PLC OMRON

    Directory of Open Access Journals (Sweden)

    Wahyudi Wahyudi

    2012-02-01

    Full Text Available The development of technology demands efficient and work speed, so it needs a system which can handleseveral things.This problem can be covered with PLC (Programmable Logic Control that can integrateseveral self standing component to be an integrated control system and can be changed the configurationwithout change all instrument. Modify the ladder program can alter system of PLC. This paper showsHoist Hanger system in PTC/ED (Pre Treatment Chemical/Electrocoat Dispotition process that controlledby PLC. Above input from limit switch, sensor, or the other input, PLC system drives the motorrelay Hoist Hanger machine. That cause the motor relay Hoist Hanger change its condition, so the movingof Hoist Hanger machine will be suitable with PLC program.

  14. Enrico Biasin - Giovanna Maina - Federico Zecca (Eds., Porn After Porn. Contemporary Alternative Pornographies

    Directory of Open Access Journals (Sweden)

    Mirko Lino

    2015-05-01

    Full Text Available Dopo Il Porno Espanso, recensito a suo tempo su Between, il nuovo libro a cura di Enrico Biasin, Giovanna Maina e Federico Zecca, Porn After Porn, è il primo tassello di un'interessante collana, “Mapping Pornographies: Histories, Geographies, Cultures”, che ha l'obiettivo di fornire materiali e strumenti metodologici al dibattito scientifico sulla pornografia contemporanea.I contributi che compongono il volume, dai saggi prettamente accademici alle testimonianze di artisti, produttori e registi del porno, creano tra loro fitte geometrie tematiche che illustrano i corpi, gli usi dei new media, gli sguardi e i consumi delle pornografie alternative, dalla loro proliferazione in Rete alla democratizzazione dell'accesso ai piaceri visivi inscritti nella fruizione di contenuti hard-core a pubblici non esclusivamente maschili ed eterosessuali.

  15. Microstructure evolution of directionally solidifi ed Sn-16%Sb hyperperitectic alloy

    Directory of Open Access Journals (Sweden)

    Li Shuangming

    2008-11-01

    Full Text Available The directionally solidifi ed microstructure of Sn-16%Sb hyperperitectic alloy has been investigated at various solidifi cation rates using a high-thermal gradient directional solidifi cation apparatus. The results indicate that the solidifi cation microstructure consists of hard primary intermetallic SnSb phase embedded in a matrix of soft peritectic β-Sn phase. The primary SnSb phase exhibits faceted growth with tetragonal or trigonal shapes. At the same time, the primary SnSb phase is refi ned with an increase in the solidifi cation rate and dispersed more uniformly in the matrix of β-Sn phase. The volume fraction of the SnSb phase fi rstly decreases and then increases when the solidifi cation rate increases in directional solidifi cation of Sn-16%Sb hyperperitectic alloy.

  16. Book Review: The Communicating Leader: The key to strategic alignment (2nd Ed

    Directory of Open Access Journals (Sweden)

    X. C. Birkenbach

    2003-10-01

    Full Text Available Title: The Communicating Leader: The key to strategic alignment (2nd Ed Author: Gustav Puth Publisher: Van Schaik Publishers Reviewer: XC Birkenbach The aim of the book according to the author, is "meant to be a usable tool, an instrument in the toolbox of the real leader and leadership student". The book is written in conversational style (as intended by the author and the 219 pages of the 10 chapters are logically packaged into three parts. While the main emphasis is naturally on leadership and communication, the coverage includes topics typically encountered in Organisational Behaviour or Management texts, e.g., organizational culture, managing change, motivation, conflict management and strategic management.

  17. Learning profiles of Master students

    DEFF Research Database (Denmark)

    Sprogøe, Jonas; Hemmingsen, Lis

    2005-01-01

    at DPU in 2001 several evaluations and research have been carried out on several topics relating to form, content, and didactics, but one important focus is missing: the research about the psychological profile and learning style of the master student. Knowledge is lacking on how teaching methods...... and programme designs relate to and support the learning profiles and learning styles of the master students. In other words: What are the consequences of the students' learning styles in terms of planning and teaching in the master programme?......Master education as a part of lifelong learning/education has over the last years increased in Denmark. Danish Universities now offer more than110 different programmes. One of the characteristics of the master education is that the students get credits for their prior learning and practical work...

  18. Grey-scale conversion X-ray mapping by EDS of multielement and multiphase layered microstructures

    DEFF Research Database (Denmark)

    Dahl, Kristian Vinter; Hald, John; Horsewell, Andy

    2007-01-01

    procedure for grey-scale conversion of energy dispersive spectroscopy X-ray maps has been developed, which is particularly useful for the plotting of line composition profiles across modified layered engineering surfaces. The method involves (a) the collection of grey-scale elemental maps, (b...... be considered as a rapid alternative to energy dispersive spectroscopy spectrum imaging. The composition profiles obtained may be conveniently compared with results of multicomponent thermodynamic modelling of interdiffusion....

  19. The FAST-ED App: A Smartphone Platform for the Field Triage of Patients With Stroke.

    Science.gov (United States)

    Nogueira, Raul G; Silva, Gisele S; Lima, Fabricio O; Yeh, Yu-Chih; Fleming, Carol; Branco, Daniel; Yancey, Arthur H; Ratcliff, Jonathan J; Wages, Robert Keith; Doss, Earnest; Bouslama, Mehdi; Grossberg, Jonathan A; Haussen, Diogo C; Sakano, Teppei; Frankel, Michael R

    2017-05-01

    The Emergency Medical Services field triage to stroke centers has gained considerable complexity with the recent demonstration of clinical benefit of endovascular treatment for acute ischemic stroke. We sought to describe a new smartphone freeware application designed to assist Emergency Medical Services professionals with the field assessment and destination triage of patients with acute ischemic stroke. Review of the application's platform and its development as well as the different variables, assessments, algorithms, and assumptions involved. The FAST-ED (Field Assessment Stroke Triage for Emergency Destination) application is based on a built-in automated decision-making algorithm that relies on (1) a brief series of questions assessing patient's age, anticoagulant usage, time last known normal, motor weakness, gaze deviation, aphasia, and hemineglect; (2) a database of all regional stroke centers according to their capability to provide endovascular treatment; and (3) Global Positioning System technology with real-time traffic information to compute the patient's eligibility for intravenous tissue-type plasminogen activator or endovascular treatment as well as the distances/transportation times to the different neighboring stroke centers in order to assist Emergency Medical Services professionals with the decision about the most suitable destination for any given patient with acute ischemic stroke. The FAST-ED smartphone application has great potential to improve the triage of patients with acute ischemic stroke, as it seems capable to optimize resources, reduce hospital arrivals times, and maximize the use of both intravenous tissue-type plasminogen activator and endovascular treatment ultimately leading to better clinical outcomes. Future field studies are needed to properly evaluate the impact of this tool in stroke outcomes and resource utilization. © 2017 American Heart Association, Inc.

  20. Microwave oven-related injuries treated in hospital EDs in the United States, 1990 to 2010.

    Science.gov (United States)

    Thambiraj, Dana F; Chounthirath, Thiphalak; Smith, Gary A

    2013-06-01

    The widespread availability of microwave ovens has sparked interest in injuries resulting from their use. Using a retrospective cohort design, the objective of this study is to investigate the epidemiology of microwave oven-related injuries treated in United States emergency departments (EDs) from 1990 through 2010 by analyzing data from the National Electronic Injury Surveillance System. An estimated 155959 (95% confidence interval [CI], 133515-178402) individuals with microwave oven-related injuries were treated in US hospital EDs from 1990 through 2010, which equals an average of 21 individuals per day; 60.7% were female; 63.3% were adults (≥18 years); 98.1% of injury events occurred at home; and 3.9% of patients were hospitalized. During the 21-year study period, the number and rate of microwave oven-related injuries increased significantly by 93.3% and 50.0%, respectively. The most common mechanism of injury was a spill (31.3%), and the most common body region injured was the hand and fingers (32.4%). Patients younger than 18 years were more likely to sustain an injury to their head and neck (relative risk: 1.65; 95% CI, 1.39-1.96) than adults. To our knowledge, this is the first study to investigate microwave oven-related injuries on a national scale. Microwave ovens are an important source of injury in the home in the United States. The large increases in the number and rate of these injuries underscore the need for increased prevention efforts, especially among young children. Copyright © 2013 Elsevier Inc. All rights reserved.