WorldWideScience

Sample records for professor kevin fu

  1. [Clinical application of "eight acupoints at the head" by Professor QIN Liang-fu].

    Science.gov (United States)

    Zhao, Hai-Yin; Li, Jing

    2007-10-01

    Professor QIN Liang-fu synthesizes the theories of channels of TCM and the theories of modern medicine, and in recent years, he has summed up academic thought of treating diseases by "eight acupoints at the head", and has applied them to treat cerebral diseases and relative diseases of the nervous system. In the present paper, it is introduced that professor QIN Liang-fu' effective samples in treatment of epilepsy, cervical vertigo by using acupuncture and moxibustion at "eight acupoints at the head" combined with Chinese herbs and in treatment of multiple sclerosis by acupuncture and moxibustion at the "eight acupoints at the head" combined with oral administration and external application of Chinese herbs.

  2. Cheetham, Prof. Antony Kevin

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2001 Honorary. Cheetham, Prof. Antony Kevin FRS. Date of birth: 16 November 1946. Address: Dept. of Materials Science &, Metallurgy, University of Cambridge, 27, Charles Babbage Road, Cambridge CB3 0FS, uk. Contact: Office: (+44-1223) 74 6733. Fax: (+44-1223) 33 4567

  3. Obituary: Kevin H. Prendergast, 1929-2004

    Science.gov (United States)

    Spiegel, Edward A.

    2005-12-01

    Kevin H. Prendergast, Emeritus Professor of Astronomy at Columbia University, died 8 September 2004 at the age of 75 from complications of lung cancer. He had been at Columbia for more than fifty years. I first met Kevin in the summer of 1955, during a brief visit to the Yerkes Observatory. I had gotten into a heated discussion about double stars with a fellow graduate student, who suggested that we seek arbitration from a postdoc who was just then passing by. That postdoc was Kevin Prendergast. Kevin went straight to the blackboard, unleashed a learned and insightful lecture on binary stars, and then continued on his way. He wasted no motion, then nor ever, in our long association. Kevin was not at the time particularly concerned with double stars, though he made two significant contributions to their study somewhat after our meeting. The first of these was an early discussion (1960) of the dynamics of gaseous streams in binary systems that made use of theory gleaned from a book on the gulf stream by Henry Stommel (himself a former astronomer). The second was the important suggestion, made with G.R. Burbidge, that X-rays from binary stars are produced when gas from one star falls onto a compact companion (1968). Kevin was a native of Brooklyn and, after a stint at Brooklyn Technical High School, he attended Columbia University for his undergraduate and graduate studies. He received the PhD in 1954 for an astrometry thesis under Jan Schilt. While attending Columbia, Kevin also studied at the Julliard School of Music, and he became a very accomplished musician. As a pianist, he was about as good as one can get and still be called an amateur, according to my musically knowledgeable friends. From Columbia, he went to the Yerkes Observatory for postdoctoral work with S. Chandrasekhar and developed an interest in MHD. His model of a magnetic star with a global force-free field holds an important place in the subject of stellar magnetism. The relativistic solution for a

  4. Kevin Bacon and Graph Theory

    Science.gov (United States)

    Hopkins, Brian

    2004-01-01

    The interconnected world of actors and movies is a familiar, rich example for graph theory. This paper gives the history of the "Kevin Bacon Game" and makes extensive use of a Web site to analyze the underlying graph. The main content is the classroom development of the weighted average to determine the best choice of "center" for the graph. The…

  5. FuNNy

    DEFF Research Database (Denmark)

    Madsen, Per Printz

    2005-01-01

    The purpose of this paper is to describe a tool that is easy to use for implementing self learning fuzzy systems. This tool which is called FuNNy generates fuzzy systems. The tool consists of a compiler and a C learning library. The compiler translates a fuzzy system (written in a dedicated...... language, called FuNNy language) to C. The C learning library contains the learning algorithm. The generated C code is simple standard C and therefore it can be applied to all computers with a C-compiler. The learning algorithm is either a gradient descend method based on a numerical calculation...

  6. Müügimehest koputajaks / Kevin Laye ; tekst Kreet Rosin

    Index Scriptorium Estoniae

    Laye, Kevin

    2011-01-01

    Intervjuu Kevin Laye'ga, kes on olnud ka kahekordne Euroopa meistrist karatees ja eriüksuse SAS liige, Roger Callahani loodud mõtteväljaravist (TFT, Thought Field Theraphy) ning teistest tehnikatest, mida ta on õppinud ning kasutab igapäevaselt

  7. 5-FU Metabolism in Cancer and Orally-Administrable 5-FU Drugs

    Directory of Open Access Journals (Sweden)

    Iwao Sasaki

    2010-09-01

    Full Text Available 5-Fluorouracil (5-FU is a key anticancer drug that for its broad antitumor activity, as well as for its synergism with other anticancer drugs, has been used to treat various types of malignancies. In chemotherapeutic regimens, 5-FU has been combined with oxaliplatin, irinotecan and other drugs as a continuous intravenous infusion. Recent clinical chemotherapy studies have shown that several of the regimens with oral 5-FU drugs are not inferior compared to those involving continuous 5-FU infusion chemotherapy, and it is probable that in some regimens continuous 5-FU infusion can be replaced by oral 5-FU drugs. Historically, both the pharmaceutical industry and academia in Japan have been involved in the development of oral 5-FU drugs, and this review will focus on the current knowledge of 5-FU anabolism and catabolism, and the available information about the various orally-administrable 5-FU drugs, including UFT, S-1 and capecitabine. Clinical studies comparing the efficacy and adverse events of S-1 and capecitabine have been reported, and the accumulated results should be utilized to optimize the treatment of cancer patients. On the other hand, it is essential to elucidate the pharmacokinetic mechanism of each of the newly-developed drugs, to correctly select the drugs for each patient in the clinical setting, and to further develop optimized drug derivatives.

  8. Spitzer IRS Observations of FU Orionis Objects

    Science.gov (United States)

    Green, J. D.; Hartmann, L.; Calvet, N.; Watson, D. M.; Ibrahimov, M.; Furlan, E.; Sargent, B.; Forrest, W. J.

    2006-09-01

    We present 5-35 μm spectra, taken with the Infrared Spectrograph (IRS) on the Spitzer Space Telescope, of five FU Orionis objects: FU Ori, V1515 Cyg, V1057 Cyg, BBW 76, and V346 Nor. All but V346 Nor reveal amorphous silicate grains in emission at 10 and 20 μm, and show water-vapor absorption bands at 5.8 and 6.8 μm and SiO or possibly methane absorption at 8 μm. These absorption features closely match these bands in model stellar photospheres-signs of the gaseous photospheres of the inner regions of these objects' accretion disks. The continuum emission at 5-8 μm is also consistent with such disks, and, for FU Orionis and BBW 76, longer wavelength emission may be fit by a model that includes moderate disk flaring. V1057 Cyg and V1515 Cyg have much more emission at longer wavelengths than the others, perhaps evidence of a substantial remnant of their natal, infalling envelopes.

  9. Roles of emeriti professors

    OpenAIRE

    Thody, Angela

    2008-01-01

    Emeritus Professor Angela Thody commenced a study of emeriti professors in 2006 when she herself had become an emeritus in 2003 and was seeking to establish an Association for emeriti at her university at Lincoln. By 2008, the literature review was finished and a pilot study of emeriti professors at Leicester University was underway. This presentation was one of several to the University of Lincoln's College of Professors to encourage their support for the formation of the association and to ...

  10. PROFESSOR ENSERMU KELBESSA

    African Journals Online (AJOL)

    2016-08-14

    Aug 14, 2016 ... University, Sweden in 1990. Although still very young, Professor Ensermu Kelbessa joined the Addis Ababa. University's Biology Department as a graduate assistant in 1979. He then went on to serve the university in various positions including: Lecturer, Assistant Professor, Associate. Professor and, finally ...

  11. The FU gene and its possible protein isoforms

    Directory of Open Access Journals (Sweden)

    Nöthen Markus M

    2004-07-01

    Full Text Available Abstract Background FU is the human homologue of the Drosophila gene fused whose product fused is a positive regulator of the transcription factor Cubitus interruptus (Ci. Thus, FU may act as a regulator of the human counterparts of Ci, the GLI transcription factors. Since Ci and GLI are targets of Hedgehog signaling in development and morphogenesis, it is expected that FU plays an important role in Sonic, Desert and/or Indian Hedgehog induced cellular signaling. Results The FU gene was identified on chromosome 2q35 at 217.56 Mb and its exon-intron organization determined. The human developmental disorder Syndactyly type 1 (SD1 maps to this region on chromosome 2 and the FU coding region was sequenced using genomic DNA from an affected individual in a linked family. While no FU mutations were found, three single nucleotide polymorphisms were identified. The expression pattern of FU was thoroughly investigated and all examined tissues express FU. It is also clear that different tissues express transcripts of different sizes and some tissues express more than one transcript. By means of nested PCR of specific regions in RT/PCR generated cDNA, it was possible to verify two alternative splicing events. This also suggests the existence of at least two additional protein isoforms besides the FU protein that has previously been described. This long FU and a much shorter isoform were compared for the ability to regulate GLI1 and GLI2. None of the FU isoforms showed any effects on GLI1 induced transcription but the long form can enhance GLI2 activity. Apparently FU did not have any effect on SUFU induced inhibition of GLI. Conclusions The FU gene and its genomic structure was identified. FU is a candidate gene for SD1, but we have not identified a pathogenic mutation in the FU coding region in a family with SD1. The sequence information and expression analyses show that transcripts of different sizes are expressed and subjected to alternative splicing

  12. Conversation Currents: Story, Relationships, and Healthy Eating: An Interview with Chef Kevin Gillespie

    Science.gov (United States)

    Language Arts, 2013

    2013-01-01

    This Conversation Currents features Chef Kevin Gillespie, owner of Atlanta restaurant Gunshow, contestant on Bravo's "Top Chef Las Vegas" in 2009, and food activist for various organizations. He shares his journey to becoming a chef, ways to integrate healthy foods in schools, and the role of literacy in nutrition.

  13. Siim Nestor soovitab : Goldie. Kevin Saunderson. Nicole Willis. King Britt / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-

    2005-01-01

    Popmuusikaüritustest: briti muusik Goldie esineb jungle-muusikaga Tallinnas 21. apr. klubis Privé, DJ Kevin Saunderson 22. apr. klubis Privé, laulja Nicole Willis 27. apr. BonBon Jazz Lounge'il klubis BonBon, Philadelphia muusik King Britt ja Eesti ansambel Broken Time Orchestra esitlevad oma heliplaate

  14. Professor Volker Claus: vom o. Professor zum e-Professor

    Science.gov (United States)

    Gunzenhäuser, Rul; Taras, Christiane; Wörner, Michael

    Der Beitrag würdigt das Wirken von Professor Claus auf Gebieten des rechnerunterstützten Lehrens. Dabei wird ein Bogen von den frühen Systemen des rechnerunterstützten Lehrens über moderne Lernplattformen im Internet zu neuen Anwendungen web-basierter Systeme für das lebenslange Lehren und Lernen gespannt.

  15. A Professor's Work.

    Science.gov (United States)

    Melko, Matthew

    This book describes a year-long participant-observer case study of the professorship as a profession. Following an introductory chapter, each chapter examines one aspect of the professor's occupation by recounting the specific experiences of the author, a sociology professor at Wright State University (Ohio). Chapter 2 looks at the department as…

  16. Kevin Traverse-Healy: kommunikatsiooni eesmärk on muuta käitumist / intervjueerinud Annela Laaneots

    Index Scriptorium Estoniae

    Traverse-Healy, Kevin

    2013-01-01

    Intervjuu strateegianõuniku ja rahvusvaheliselt tuntud kommunikatsioonieksperdi Kevin Traverse-Healyga, kes peab eduka kommunikatsioonijuhi töös oluliseks luua õige kommunikatsioon, mille eesmärgiks on sihtrühma käitumise muutus

  17. Professor Martin Hairer

    Directory of Open Access Journals (Sweden)

    Martine Barons

    2015-09-01

    Full Text Available Professor Martin Hairer was one of four recipients of the 2014 Fields Medal, widely viewed as the highest honour a mathematician can receive. He is currently Regius Professor of Mathematics in the Mathematics Department at the University of Warwick. Professor Hairer has contributed significantly to the field of stochastic partial differential equations (SPDEs, which engages with interdisciplinary approaches to mathematics and physics. He has enjoyed great success communicating mathematics to a range of audiences and has also developed music editing software.In this interview, early career mathematicians, Dr Martine Barons (MJB and Dr Paul Chleboun ask Professor Hairer (MH about how his interest in mathematics developed; the awards ceremony where he received the Fields Medal; Amadeus Pro, the music software he developed and continues to maintain; and the challenges of engaging a sceptical and sometimes critical public as a mathematician.

  18. Cellular response to 5-fluorouracil (5-FU in 5-FU-resistant colon cancer cell lines during treatment and recovery

    Directory of Open Access Journals (Sweden)

    Kravik Katherine L

    2006-05-01

    Full Text Available Abstract Background Treatment of cells with the anti-cancer drug 5-fluorouracil (5-FU causes DNA damage, which in turn affects cell proliferation and survival. Two stable wild-type TP53 5-FU-resistant cell lines, ContinB and ContinD, generated from the HCT116 colon cancer cell line, demonstrate moderate and strong resistance to 5-FU, respectively, markedly-reduced levels of 5-FU-induced apoptosis, and alterations in expression levels of a number of key cell cycle- and apoptosis-regulatory genes as a result of resistance development. The aim of the present study was to determine potential differential responses to 8 and 24-hour 5-FU treatment in these resistant cell lines. We assessed levels of 5-FU uptake into DNA, cell cycle effects and apoptosis induction throughout treatment and recovery periods for each cell line, and alterations in expression levels of DNA damage response-, cell cycle- and apoptosis-regulatory genes in response to short-term drug exposure. Results 5-FU treatment for 24 hours resulted in S phase arrests, p53 accumulation, up-regulation of p53-target genes on DNA damage response (ATF3, GADD34, GADD45A, PCNA, cell cycle-regulatory (CDKN1A, and apoptosis-regulatory pathways (FAS, and apoptosis induction in the parental and resistant cell lines. Levels of 5-FU incorporation into DNA were similar for the cell lines. The pattern of cell cycle progression during recovery demonstrated consistently that the 5-FU-resistant cell lines had the smallest S phase fractions and the largest G2(/M fractions. The strongly 5-FU-resistant ContinD cell line had the smallest S phase arrests, the lowest CDKN1A levels, and the lowest levels of 5-FU-induced apoptosis throughout the treatment and recovery periods, and the fastest recovery of exponential growth (10 days compared to the other two cell lines. The moderately 5-FU-resistant ContinB cell line had comparatively lower apoptotic levels than the parental cells during treatment and recovery

  19. Inter-acción! : Música y cine en "Acción!" de Kevin Johansen

    OpenAIRE

    Mauri Ungaro, Inés; Páez Gallini, Micaela; Duarte Loza, Daniel Martín

    2016-01-01

    El siguiente trabajo de investigación parte de la propuesta interdisciplinaria planteada por Kevin Johansen en la canción intitulada ''Acción!'' del disco Sur O No Sur (2002) para dilucidar qué elementos la componen tanto en materia poético-guionística como musical y, a partir de allí, poner de relieve la interacción manifiesta entre música y cine. Realizamos, entonces, un pormenorizado análisis de la letra de la canción y, sobre todo, nos enfocamos a desentramar cuáles son las palabras que e...

  20. Professor Michael Levitt

    Directory of Open Access Journals (Sweden)

    Gemma-Louise Davies

    2015-10-01

    Full Text Available Professor Michael Levitt (Stanford University, USA won the 2013 Nobel Prize in Chemistry for the development of multiscale models for complex chemical systems—computational tools which can calculate the course of chemical reactions. Professor Levitt was born in Pretoria, South Africa; he came to the UK on a summer vacation aged 16, where he decided to stay and study for his A‑levels. His interest in the physics of living systems drove him to study biophysics at King’s College London, before securing a PhD position at the Laboratory of Molecular Biology in Cambridge. In the interim year between his degree and beginning his PhD, Professor Levitt worked at the Weizmann Institute of Science in Israel, where he met his future wife. They married later that year and moved to Cambridge, where their three children were born. After completing his PhD, he spent time working in Israel, Cambridge, the Salk Institute and Stanford (both California. Since 1986, he has split his time between Israel and California. Outside of science, he is a keen hiker and he is well-known to have attended the eclectic ‘Burning Man’ Festival in California.[1]Professor Levitt visited the University of Warwick to speak at the Computational Molecular Science Annual Conference in March 2015. In this interview, Dr Gemma-Louise Davies, an Institute of Advanced Study Global Research Fellow, spoke to Professor Levitt about the importance of Interdisciplinarity in his field, role models in Academia, and his plans for the future.Image: Professor Michael Levitt (left with Dr Scott Habershon (right, organiser of the 2015 Computational Molecular Science Annual Conference during his visit to the University of Warwick in March 2015.[1] ‘Burning Man’ is a unique annual festival dedicated to community, art, music, self-expression and self-reliance. Tens of thousands of people flock to this temporary metropolis built in the Californian desert.

  1. World-Hating: Apocalypse and Trauma in We Need to Talk about Kevin

    Directory of Open Access Journals (Sweden)

    Sean Desilets

    2017-11-01

    Full Text Available Lynne Ramsay’s 2011 film We Need to Talk about Kevin alternates between two narrative times, one occurring before its protagonist Eva’s son commits a terrible crime, and one after. The film invites us to read the crime as a traumatic event in Eva’s life, an event of such terrible force that it transforms Eva’s identity. This essay uses Jacob Taubes’s understanding of Gnosticism to suggest that this event does not transform who Eva is, but rather how she knows. Like a Gnostic believer, Eva comes to understanding the fundamental ontological evil of community life. Eva’s ‘trauma,’ her alienation from the world she occupies, predates Kevin’s crime, but the aftermath of that crime reveals her alienation to her. The worldview thus presented by the film casts some light on how art house films are marketed. Like many middlebrow products, art house films present marketers with the challenge of concealing the fact that the commodity they are selling is indeed a commodity. This ambivalent distrust of the marketplace is a softened repetition of the Gnostic’s anticosmism, and We Need to Talk About Kevin both performs and thematizes a displacement from the world that is primary, not contingent upon any traumatic event.

  2. Professor Kalkman retires

    NARCIS (Netherlands)

    Baas, Pieter

    1991-01-01

    On 13 December 1990 Prof. Dr. Cornelis (Kees) Kalkman retired from the positions of Professor of Plant Systematics and Scientific Director of the Rijksherbarium/ Hortus Botanicus by presenting his valedictory lecture to the academic community of Leiden University and the assembled Dutch Botanical

  3. Professor Wolfgang Panofsky

    CERN Multimedia

    2007-01-01

    "Professor Wolfgang panofsky, who died on September 24 aged 88, was a particle physicists and director of the Stanford Linear Accelerator Centre (SLAC) in California; with Jack Steinberger, he was the first to isolate the neutral pi meson, one of the subatomic particles which had been predicted by theoretical scientists to account for the strng force which binds the nuclei of atoms." (1 page)

  4. Professor Tiina Tasmuth Helsingis

    Index Scriptorium Estoniae

    2000-01-01

    Tervisekasvatuse õppetooli professor Tiina Tasmuth osales 11.-14. juunini Helsingis toimunud rahvusvahelise konverentsi "2nd Psycho-Social Impacts of Breast Cancer" töös ning esines ettekandega teemal "Chronic post-treatment symptoms in patients with breast cancer" : [täistekst

  5. Professor og DMI

    DEFF Research Database (Denmark)

    Kaas, Eigil

    2010-01-01

    oplever meget lave temperaturer - og for Danmarks vedkommende en usædvanlig lang periode med vintervejr. Forklaringen kommer fra professor Eigil Kaas fra Niels Bohr Instituttet ved Københavns Universitet. Han forklarer til jp.dk, at vintervejret dog er betinget af den mere eller mindre tilfældige måde...

  6. The Phonetical Properties of Fu-Yü Kyrgyz Language

    OpenAIRE

    KASAPOĞLU-ÇENGEL, Hülya

    2016-01-01

    The Kyrgyz people, who live in the Fu-Yü part of Manchuria and for whom their being the grandsons of the old Kyrgyz people and the Fu-Yü Kyrgyz language which is being spoken in the region are among the subjects, which the Turkology circles are interested in the recent years. The data, which are related to the subject are rather insufficient and are limited by the material, which has been published by Hu Zhenhua, E. Tenişev and Guy Imart. These data also have been the origin of the further r...

  7. Professors' Observations on Their Work.

    Science.gov (United States)

    Myers, Betty; Mager, Gerald M.

    Previous studies of professors of education have noted what activities comprised the work of being a professor, how professors allocated time to the various work tasks, how they would have preferred to allocate time, and insights they had about their work. In this study, parallel data were gathered on the broader education professoriate. Survey…

  8. AHP 37: KEVIN STUART AMONG MONGOLIAN ENGLISHLEARNERS IN HUHHOT DURING THE MID-1980S

    Directory of Open Access Journals (Sweden)

    Mandula Borjigin

    2015-06-01

    Full Text Available In the mid-1980s, Southern Mongolia (Inner Mongolia was still at the early stage of opening its door to Westerners. In Huhhot, the capital of Southern Mongolia, there were only a handful of Westerners visiting, teaching English, or studying at the various colleges, and only for limited periods of time. In fact, foreigners were so few and cherished that they were often invited by the governor of Southern Mongolia to attend such state events as the annual Tsagaan Sar 'Lunar New Year' Celebration. The appearance of foreigners at these auspicious events was interpreted as a symbol of how the government was making an effort to introduce foreign investments and ideas to the economic and political reforms. Kevin was one of the respected foreigners working in Huhhot at that time. ...

  9. Tenemos que hablar de Kevin (2011. La violencia filio?parental

    Directory of Open Access Journals (Sweden)

    Carmen VIZOSO GÓMEZ

    2017-03-01

    Full Text Available La violencia filio?parental supone un serio problema para las instituciones sanitarias y sociales a causa de los efectosnocivos que conlleva en el bienestar familiar y en la armonía social. El objetivo de este trabajo consiste en analizarla película Tenemos que hablar de Kevin, dirigida por Lynne Ramsay. Por tanto, se describen las situaciones, los discursos,los conflictos y las particularidades que caracterizan a los personajes para explicar la violencia ejercida porun hijo hacia su madre. Además, se contempla la utilidad del empleo de esta película como instrumento educativopara la formación de los jóvenes y los futuros profesionales.

  10. Redatuming of borehole-to-surface electromagnetic data at the Kevin Dome exploration site

    DEFF Research Database (Denmark)

    Cai, Hongzhu; Zhdanov, Michael

    2013-01-01

    The method of redatuming the controlled-source electromagnetic data was introduced in Zhdanov and Cai (2012). The approach is based on a Stratton-Chu type integral and the Lorentz lemma to relate observed EM data on the earth’s surface to EM data on some horizontal plane P located underground....... This upward continuation problem is always well posed. By doing this, we can place more virtual receivers at the earth’s surface and within a much larger area. Compared to traditional interpolation and extrapolation techniques such as polynomial fitting or spline approximation, our method takes into account...... the physics of the EM field, which makes the redatuming more accurate than simple mathematical transformation. In this paper, we illustrate this method by redatuming of borehole-to-surface electromagnetic data at the Kevin Dome exploration site....

  11. Professor Stewart's incredible numbers

    CERN Document Server

    Stewart, Ian

    2015-01-01

    Ian Stewart explores the astonishing properties of numbers from 1 to10 to zero and infinity, including one figure that, if you wrote it out, would span the universe. He looks at every kind of number you can think of - real, imaginary, rational, irrational, positive and negative - along with several you might have thought you couldn't think of. He explains the insights of the ancient mathematicians, shows how numbers have evolved through the ages, and reveals the way numerical theory enables everyday life. Under Professor Stewart's guidance you will discover the mathematics of codes,

  12. Professor Alex Callinicos

    Directory of Open Access Journals (Sweden)

    Ali Saqer

    2016-04-01

    Full Text Available Professor Alex Callinicos is a renowned social theorist and scholar of international political economy. He conducts research on Marx and Marxism, European social and political theory, contemporary political philosophy, critical theory, historiography, and international political economy. His work provides invaluable insights on issues of race and racism, social justice, the Third Way, imperialism, austerity, and EU politics, among many other fascinating contemporary issues. Alex studied Philosophy, Politics, and Economics at Balliol College, Oxford, and Philosophy of Science at the London School of Economics before writing a DPhil on Marx's Capital, also at Balliol. He was a Junior Research Fellow in Contemporary Social Thought at St Peter's College, Oxford from 1979 to 1981, after which he taught social and political theory at the Department of Politics at the University of York until 2005, when he moved to King's College London. Alex is currently the Professor of European Studies at King's and editor of International Socialism. Alex has been an active contributor to the development of the movement for another globalization, participating in the World Social Forum and an animator of the European Social Forum. Among his best known books are The Revolutionary Ideas of Karl Marx (1983, Against Postmodernism (1990, Social Theory (1999, An Anti-Capitalist Manifesto (2003, The Resources of Critique (2006, Imperialism and Global Political Economy (2009. His most recent book is entitled Deciphering Capital: Marx’s Capital and its Destiny (2014.

  13. High resolution spectroscopy of the new FU Orionis object BBW 76

    Science.gov (United States)

    Eisloeffel, J.; Hessman, F. V.; Mundt, R.

    1990-06-01

    High-resolution spectra of the new FU Orionis object BBW 76 are presented. Although the photometric outburst of this FU Orionis object could not be observed, its spectral characteristics clearly identify it as belonging to this class. BBW 76 shows Balmer line profiles typical for FU Orionis stars. Its absorption line spectrum and, in particular, the line widths are strikingly similar to that of FU Ori. Other similarities to FU Ori are the presence of an arclike nebula, and the FIR luminosities and color temperatures.

  14. Risk Assessment of Carbon Sequestration into A Naturally Fractured Reservoir at Kevin Dome, Montana

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Minh [Univ. of Wyoming, Laramie, WY (United States); Onishi, Tsubasa [Texas A & M Univ., College Station, TX (United States); Carey, James William [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Will, Bob [Schlumberger, Houston, TX (United States); Zaluski, Wade [Schlumberger, Houston, TX (United States); Bowen, David [Montana State Univ., Bozeman, MT (United States); DeVault, Brian [Vecta Oil and Gas, Dallas, TX (United States); Duguid, Andrew [Battelle Memorial Inst., Columbus, OH (United States); Spangler, Lee [Montana State Univ., Bozeman, MT (United States); Stauffer, Philip H. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-12-22

    In this report, we describe risk assessment work done using the National Risk Assessment Partnership (NRAP) applied to CO2 storage at Kevin Dome, Montana. Geologic CO2 sequestration in saline aquifers poses certain risks including CO2/brine leakage through wells or non-sealing faults into groundwater or to the land surface. These risks are difficult to quantify due to data availability and uncertainty. One solution is to explore the consequences of these limitations by running large numbers of numerical simulations on the primary CO2 injection reservoir, shallow reservoirs/aquifers, faults, and wells to assess leakage risks and uncertainties. However, a large number of full-physics simulations is usually too computationally expensive. The NRAP integrated assessment model (NRAP-IAM) uses reduced order models (ROMs) developed from full-physics simulations to address this issue. A powerful stochastic framework allows NRAPIAM to explore complex interactions among many uncertain variables and evaluate the likely performance of potential sequestration sites.

  15. Voorwoord: Professor Andrzej Borowski

    Directory of Open Access Journals (Sweden)

    Koch Jerzy

    2015-11-01

    Full Text Available Professor Andrzej Borowski from the Jagiellonian University, whose 70th anniversary we celebrate this year, is a very well known scholar and literature historian, specialised in Old Polish Literature (Middle Ages, Renaissance and Baroque - and with a background from Classical studies. A lesser known fact is that he also is a scholar active in the field of the Netherlandish (Dutch and Flemish literature and culture: as author of numerous books and articles about (South Netherlandish figures from the 16th and 17th century, as supervisor of numerous dissertations or habilitations in the field of the Netherlandish literature and as an inspiring personality in the field of the Netherlandish studies at Polish universities. He can indeed be seen as the Spiritus Litterarum Neerlandicorum in Poland.

  16. Sexual Sadism and Masochism in Character Kevin Morano in Novel Seduction in Death by J.d Robb

    OpenAIRE

    Pelangi, Kinanti

    2017-01-01

    This final project is to analyze novel, Seduction in Death by J.D Robb. The purpose of this final project is to know sexual disorder owned by the character in the novel Seduction in Death. The sexual disorder is sadism and masochism. In analysis this novel, the writer uses a literary research method and Sigmund Freud's psychoanalysis theory. The Result shows that there are sexual needs unfulfilled by Kevin Morano that ultimately he commits sadism and masochism.

  17. 5FU resistance caused by reduced fluoro-deoxyuridine monophosphate and its reversal using deoxyuridine.

    Science.gov (United States)

    Mori, Ryutaro; Futamura, Manabu; Tanahashi, Toshiyuki; Tanaka, Yoshihiro; Matsuhashi, Nobuhisha; Yamaguchi, Kazuya; Yoshida, Kazuhiro

    2017-09-01

    The mechanism of 5-fluorouracil (5FU) resistance was investigated, focusing on the level of thymidylate synthase (TS) ternary complex formed with fluoro-deoxyuridine monophosphate (FdUMP). MKN45 and 5FU-resistant MKN45/F2R cells were treated with 5FU and fluoro-deoxyuridine (FdU) in combination with deoxyuridine (dU) and thymidine (dT). Subsequently, the levels of ternary complex were determined by western blotting and the cell viability was calculated using an MTT assay. MKN45/F2R cells exhibited 5FU resistance (56.2-fold relative to MKN45 cells), and demonstrated decreased orotate phosphoribosyltransferase (OPRT) and increased TS levels, requiring a higher concentration of 5FU to induce ternary complex formation than MKN45 cells. Following transfection of small interfering RNA against OPRT, MKN45 exhibited increased resistance to 5FU and decreased ternary complex formation subsequent to treatment with 5FU, indicating that decreased OPRT led to increased 5FU resistance. However, MKN45/F2R also exhibited resistance to FdU, which can be converted to FdUMP without OPRT, and there was decreased ternary complex formation after treatment with FdU, indicating that the 5FU-resistant cells had the ability to decrease intracellular FdUMP. The addition of dU and thymidine dT to 5FU promoted the formation of ternary complexes and reversed 5FU resistance in MKN45/F2R cells, although dT inhibited the efficacy of raltitrexed (another TS inhibitor). These results suggested that 5FU-resistant cells had the ability to reduce intracellular FdUMP irrespective of decreased OPRT, which led to resistance to 5FU. This resistance was then inhibited by treatment with dT or dU.

  18. A time for growth: an interview with Amgen CEO Kevin Sharer. Interview by Paul Hemp.

    Science.gov (United States)

    Sharer, Kevin

    2004-01-01

    Fast growth is a nice problem to have--but a hard one to manage well. In this interview, Kevin Sharer, the CEO of biotech giant Amgen, talks about the special challenges leaders face when their companies are on a roll. Sharer, who was also head of marketing at pre-WorldCom MCI and a division head and a staff assistant to Jack Welch at GE, offers insights drawn from his own experience--and from his own self-proclaimed blunders: "I learned the hard way that you need to become credible and enlist support inside the company before you start trying to be a change agent. If you think you're going to make change happen simply by force of personality or position or intellect, you'd better think again." And change there was: Under Sharer's leadership, Amgen overhauled its management team, altered its culture, and launched a couple of blockbuster products. How do chief executives survive in that kind of dizzying environment? "A CEO must always be switching between different altitudes--tasks of different levels of abstraction and specificity," Sharer says. "You might need to spend time working on a redesign of your organizational structure and then quickly switch to drafting a memo to all employees aimed at reinforcing one of the company's values." Having a supportive and capable top team is also key: "A top management team is the most revealing window into a CEO's style, values, and aspirations.... If you don't have the right top team, you won't have the right tiers below them. [The] A players won't work for B players. Maybe with a company like GE, the reputation of the company is so strong that it can attract top people to work for weaker managers. In a new company like Amgen, that won't happen."

  19. Professor Igor Yevseyev: In Memoriam Professor Igor Yevseyev: In Memoriam

    Science.gov (United States)

    2012-06-01

    Dear readers and authors, June 3, 2012 will mark five months since Professor Igor Yevseyev, Deputy Editor-in-Chief of both journals Laser Physics and Laser Physics Letters passed away, suddenly and unexpectedly. He was 67. Born in Moscow, he entered one of the world's best schools of physics, Moscow Engineering Physics Institute (MEPhI). With this renowned educational and research institution he bonded an alliance for his entire life, starting as an undergraduate student in the Department of Theoretical Physics and later continued as graduate student, assistant professor, associated professor, and full professor in the same department, a rare accomplishment of a person. All those years he retained the love of his life—the love for physics. He worked tirelessly as a teacher and scholar in this captivating field of knowledge. Professor Yevseyev was one of the founders of the international journal of Laser Physics in 1990, the first academic English language journal published in the former USSR. Later, in 2004, the second journal, Laser Physics Letters was brought to the forum of global laser physics community. The idea behind this new title was Professor Yevseyev's initiative to reach the readers and participants with new pioneering and break-through research results more rapidly. His leadership and indefatigable dedication to the quality of published materials made it possible that this journal reached international recognition in a few short years. Still, in order to attract even more attention of potential contributors and readers, Professor Yevseyev originally proposed to conduct the International Laser Physics Workshop (LPHYS) on the annual basis. Since 1992 the Workshop has been conducted every year, each year in a different country. As in all previous years, Professor Yevseyev was the key organizer of this year's workshop in Calgary, Canada. Sadly, this workshop will take place without him. Editorial Board

  20. WAVELET TRANSFORM ANALYSIS OF ELECTROMYOGRAPHY KUNG FU STRIKES DATA

    Directory of Open Access Journals (Sweden)

    Ana Carolina de Miranda Marzullo

    2009-11-01

    Full Text Available In martial arts and contact sports strikes are performed at near maximum speeds. For that reason, electromyography (EMG analysis of such movements is non-trivial. This paper has three main goals: firstly, to investigate the differences in the EMG activity of muscles during strikes performed with and without impacts; secondly, to assess the advantages of using Sum of Significant Power (SSP values instead of root mean square (rms values when analyzing EMG data; and lastly to introduce a new method of calculating median frequency values using wavelet transforms (WMDF. EMG data of the deltoid anterior (DA, triceps brachii (TB and brachioradialis (BR muscles were collected from eight Kung Fu practitioners during strikes performed with and without impacts. SSP results indicated significant higher muscle activity (p = 0.023 for the strikes with impact. WMDF results, on the other hand, indicated significant lower values (p = 0. 007 for the strikes with impact. SSP results presented higher sensitivity than rms to quantify important signal differences and, at the same time, presented lower inter-subject coefficient of variations. The result of increase in SSP values and decrease in WMDF may suggest better synchronization of motor units for the strikes with impact performed by the experienced Kung Fu practitioners

  1. Evolution of the FU Orionis Object BBW 76

    Science.gov (United States)

    Reipurth, Bo; Hartmann, Lee; Kenyon, Scott J.; Smette, Alain; Bouchet, Patrice

    2002-10-01

    We have carried out a long-term photometric and spectroscopic monitoring program of the southern FU Orionis-type object BBW 76 spanning the period from 1982 to 1997. BBW 76 has the same radial velocity as the small cloud toward which it is projected, and for which a kinematic distance of about 1.8 kpc has been derived. We have determined a large reddening of E(B-V)~0.7 for BBW 76. Optical and infrared spectra show the change toward later spectral type with increasing wavelength characteristic of FU Orionis stars and indicative of a hot luminous disk. High-resolution echelle spectra of BBW 76 show P Cygni profiles with extended blueshifted absorption troughs at the Hα and sodium lines from a neutral, supersonic wind. Comparison of such spectra obtained at six different epochs between 1985 and 1997 reveals major changes in these Hα and sodium line profiles. For a period of 10 years from 1985, the massive absorption troughs diminished in extent and depth, until by 1994 they had all but disappeared, while at the same time the blueshifted emission peak in the Hα line increased markedly in strength. However, when observed in 1997, the absorption had increased again and the emission had diminished. We interpret this in terms of an extended period during which accretion through a circumstellar disk decreased, with a resulting decrease in wind production. But the increased activity by 1997 shows that this is not a constant decay and that the star was not about to revert to its presumably original T Tauri stage. We monitored the star with optical photometry from 1983 to 1994, during which period it decreased almost monotonically in brightness by 0.2 mag in V. Infrared J, H, and K photometry from 1983 to 1991 shows a period of monotonic fading between 1984 and 1988, followed by more irregular behavior. In a search of the Harvard plate archives we have found a plate from the year 1900 on which BBW 76 is seen at approximately its present brightness, certainly not 2 mag

  2. The Profession and the Professors.

    Science.gov (United States)

    Dain, Phyllis

    1980-01-01

    Speculates on why graduate library schools have not, in the persons of their professors, produced theoretical leadership in Library Science. The ideals of professional ethical standards are contrasted with present practice. (RAA)

  3. Response to Professor Jean Guichard

    OpenAIRE

    Kargulowa, Alicja; Czerkawska, Alicja; Kłodkowska, Joanna; Siarkiewicz, Elżbieta; Zielińska-Pękał, Daria; Zierkiewicz, Edyta

    2013-01-01

    The article recounts a discussion inspired by Professor Jean Guichard’s letter to Professor Alicja Kargulowa. Its participants – a group of female counsellogists – are engaged in an e-mail exchange that freely unfolds in the symbolic space of the on-line discourse. Embedded in their own specific research, their contributions depart from a conventional, structured line of argumentation, spontaneously, and at the same time insightfully, reflecting on various facets of purification and translati...

  4. FuGEFlow: data model and markup language for flow cytometry

    Directory of Open Access Journals (Sweden)

    Manion Frank J

    2009-06-01

    Full Text Available Abstract Background Flow cytometry technology is widely used in both health care and research. The rapid expansion of flow cytometry applications has outpaced the development of data storage and analysis tools. Collaborative efforts being taken to eliminate this gap include building common vocabularies and ontologies, designing generic data models, and defining data exchange formats. The Minimum Information about a Flow Cytometry Experiment (MIFlowCyt standard was recently adopted by the International Society for Advancement of Cytometry. This standard guides researchers on the information that should be included in peer reviewed publications, but it is insufficient for data exchange and integration between computational systems. The Functional Genomics Experiment (FuGE formalizes common aspects of comprehensive and high throughput experiments across different biological technologies. We have extended FuGE object model to accommodate flow cytometry data and metadata. Methods We used the MagicDraw modelling tool to design a UML model (Flow-OM according to the FuGE extension guidelines and the AndroMDA toolkit to transform the model to a markup language (Flow-ML. We mapped each MIFlowCyt term to either an existing FuGE class or to a new FuGEFlow class. The development environment was validated by comparing the official FuGE XSD to the schema we generated from the FuGE object model using our configuration. After the Flow-OM model was completed, the final version of the Flow-ML was generated and validated against an example MIFlowCyt compliant experiment description. Results The extension of FuGE for flow cytometry has resulted in a generic FuGE-compliant data model (FuGEFlow, which accommodates and links together all information required by MIFlowCyt. The FuGEFlow model can be used to build software and databases using FuGE software toolkits to facilitate automated exchange and manipulation of potentially large flow cytometry experimental data sets

  5. Mitomycin-C and 5- FU in ophthalmology: review article

    Directory of Open Access Journals (Sweden)

    M Jabbarvand Behrouz

    2009-03-01

    Full Text Available "nThe response of living tissues to the surgical trauma is associated with varying degrees of tissue repair and involves two distinct processes including replacement and regeneration. Replacement results in scar tissue formation instead of restoration of the normal architecture. However, regeneration leads to restoration of the original architecture leaving no sign of injury. Anti-proliferative agents are used to inhibit tissue responses to surgical trauma. Among them mitomycin- C and 5- FU had gained increasing applications in ophthalmic surgeries, including filtering glaucoma surgeries, laser vision correction with excimer laser by ablative surface refractive surgery, reconstructive surgeries for ocular surface disorders and removal of neoplastic tissues and secondary operations on nasolacrimal ducts. In this review article, the various aspects of applications of these agents including their mechanism of action, function, mode of application and complications in different ophthalmology fields are discussed.

  6. Multiple shoot induction and rooting of Paeonia lactiflora 'Da Fu Gui ...

    African Journals Online (AJOL)

    Shoot height at the time of inoculation had a great effect on proliferation and growth of 'Da Fu Gui'. Putrescine (Put) (0.5 to 5.0 mg l-1) prevented rooting of 'Da Fu Gui' but it favored the development of roots. Highest rooting percentage was observed on half-strength MS medium (double-strength Ca2+) supplemented with 1 ...

  7. Il professor Mitja Skubic ottuagenario

    Directory of Open Access Journals (Sweden)

    Martina Ožbot

    2008-12-01

    Full Text Available Incredibile ma vero: il professor Mitja Skubic si trova, questa volta lui stesso, al centro dell’attenzione anziché essere il motore, il perno dell’attività. La ragione per questo attimo di respiro è il suo ottantesimo compleanno, a dire il vero passato già da tempo. È pressoché una contingenza aneddotica quella per cui il volume dedicatogli per l’occasione viene pubblicato così tardi: il professore ha continuato a tener d’occhio la nostra rivista ben dopo aver nominato i nuovi direttori tanto che sarebbe stato impossibile sorprenderlo con una miscellanea di contributi in suo onore.

  8. [Multi-needling in rows acupuncture created by professor HAN Jing-xian].

    Science.gov (United States)

    Wang, Tao

    2012-07-01

    The multi-needling in rows acupuncture is created by professor HAN Jing-xin, in which the cutaneous region, muscle region and meridian are involved in treatment in terms of the depth of disease and the location of treatment. The multi-needling in rows acupuncture on the cutaneous region is for the disorders of the cutaneous superficial area, characterized as shallow puncturing to the skin layer. The multi-needling in rows acupuncture on the muscle region is for the disorders of the muscle region, characterized as needling the muscle regions with the multiple meridians involved, but without the meridian distributions concerned. The multi-needling in rows acupuncture on the meridian is used at the meridian points in terms of the meridian disorders and Zang fu disorders. The multi-needling in rows acupuncture for meridian disorders is applied to treat the local disorders on the running course of the meridian. The multi-needling in rows acupuncture for Zang fu disorders is used to treat the relevant Zang fu disorders in terms of the running course of the meridian, in which, the multi-needling in rows acupuncture at the Back-shu points is used specially for the disorders of the thoracic and abdominal organs and systems with the disturbance of the autonomic nerves included; the multi-needling in rows acupuncture at the three meridians in occipital region is specially for vertigo and ataxia induced by the cerebella disorders.

  9. Professor@s e Eros Teachers and Eros

    Directory of Open Access Journals (Sweden)

    Deborah P. Britzman

    2009-01-01

    Full Text Available Professores/as são testemunhas do fantástico mundo da sexualidade. Esse artigo explora a centralidade de Eros para a educação e estabelece uma relação entre o desejo do/a professor/a e os acontecimentos emocionais da relação própria relação aluno/professor. Eu proponho que o aprendizado deva envolver nosso "eu" erótico, além das nossas fantasias. Mas esta perspectiva requer que professores/as considerem uma psicologia do amor como um caminho principal para a as situações emocionais de Eros. Na sua conclusão este trabalho sugere uma pedagogia que dê as boas vindas tanto à homossexualidade como a heterossexualidade como expressões humanas do amor.Teachers bear witness to the wondrous world of sexuality. This essay explores the centrality of Eros to education and links the teacher's desire to the emotional situation of the student/teacher relationship. I propose that learning involves our erotic selves and our fantasy life. But such a view requires that teachers consider a psychology of love as lending insight into the emotional situation of Eros. The paper concludes by suggesting a pedagogy that welcomes homosexuality and heterosexuality as human expressions of love.

  10. γ-Tocotrienol prevents 5-FU-induced reactive oxygen species production in human oral keratinocytes through the stabilization of 5-FU-induced activation of Nrf2.

    Science.gov (United States)

    Takano, Hideyuki; Momota, Yukihiro; Kani, Kouichi; Aota, Keiko; Yamamura, Yoshiko; Yamanoi, Tomoko; Azuma, Masayuki

    2015-04-01

    Chemotherapy-induced oral mucositis is a common adverse event in patients with oral squamous cell carcinoma, and is initiated through a variety of mechanisms, including the generation of reactive oxygen species (ROS). In this study, we examined the preventive effect of γ-tocotrienol on the 5-FU-induced ROS production in human oral keratinocytes (RT7). We treated RT7 cells with 5-FU and γ-tocotrienol at concentrations of 10 µg/ml and 10 nM, respectively. When cells were treated with 5-FU alone, significant growth inhibition was observed as compared to untreated cells. This inhibition was, in part, due to the ROS gene-rated by 5-FU treatment, because N-acetyl cysteine (NAC), a ROS scavenger, significantly ameliorated the growth of RT7 cells. γ-tocotrienol showed no cytotoxic effect on the growth of RT7 cells. Simultaneous treatment of cells with these agents resulted in the significant recovery of cell growth, owing to the suppression of ROS generation by γ-tocotrienol. Whereas 5-FU stimulated the expression of NF-E2-related factor 2 (Nrf2) protein in the nucleus up to 12 h after treatment of RT7 cells, γ-tocotrienol had no obvious effect on the expression of nuclear Nrf2 protein. Of note, the combined treatment with both agents stabilized the 5-FU-induced nuclear Nrf2 protein expression until 24 h after treatment. In addition, expression of Nrf2-dependent antioxidant genes, such as heme oxygenase-1 (HO-1) and quinone oxidoreductase-1 (NQO-1), was significantly augmented by treatment of cells with both agents. These findings suggest that γ-tocotrienol could prevent 5-FU-induced ROS generation by stabilizing Nrf2 activation, thereby leading to ROS detoxification and cell survival in human oral keratinocytes.

  11. Professors of the New Economy.

    Science.gov (United States)

    Wilson, Robin

    2000-01-01

    Profiles four professors who epitomize the increasing influence of academe on new technology-driven Internet business: a start-up maven, Steven Kaplan; a social psychologist, Michael Ray; a cyberlawyer, David Post; and an e-commerce expert, Andrew B. Whinston. (DB)

  12. Ezra Pound and Du Fu: Gazing at Mt. Tai

    Directory of Open Access Journals (Sweden)

    Kent Su

    2017-08-01

    Full Text Available Confined to a six-by-six-foot outdoor steel cage, Ezra Pound saw a series of mountain hills from a few miles to the east of Pisa. The poet compared one of these small 800-metre hills to the sacred Chinese Mt. Tai, which becomes the most common geographical name in The Pisan Cantos. Pound’s poetic summoning of this particular mountain is related to the fact that Mt. Tai is historically and culturally connected to the philosophy of Confucius, who personally ascended the mountain several times. Pound, as a devout Confucian disciple, closely follows the philosophical doctrines and attempts to mentally trace the footsteps of Confucius. This paper will argue how Pound’s poetic evocation of the mountain shares a striking similarity to an eighth-century Chinese poem called “Gazing at Mt. Tai,” which was written by the famous literatus - Du Fu 杜甫(712 – 770 . In spite of living in two completely different eras and countries, Pound’s and Du Fu’s reference to Mt. Tai demonstrates the confluence of their poetic spirits. Neither of them ascended mountain personally. They instead made use of their poetic imagination to follow the paths of Confucius and perceived the mountain as an earthly paradise, one which represents tranquillity and serenity away from the moral and physical corruption of the external world.

  13. NOTES ON CONTRIBUTORS H. Johnson Nenty, Professor ...

    African Journals Online (AJOL)

    Admin

    NOTES ON CONTRIBUTORS. H. Johnson Nenty, Professor, Educational Research, Measurement and Evaluation, Department of Educational. Foundations, University of Botswana Idowu Biao, Professor of Lifelong learning, Department of Adult Education,. University of Botswana. Cletus K. Mbowura, Lecturer, Department of ...

  14. ICT Use by Journalism Professors in Colombia

    Science.gov (United States)

    Hung, Elias Said

    2011-01-01

    This article analyses how journalism professors at Colombian universities use information and communications technologies (ICT) in their teaching. Survey data was obtained during the first trimester of 2009 from 63 professors in journalism departments and from a total of 865 professors who are affiliated with journalism departments at 29…

  15. Erratum: Professor J. H. S. Gear

    African Journals Online (AJOL)

    s short of their. Lesley, a nd their amily a proper Wake on 15 November 1994. Erratum: Professor J. H. S. Gear. The name of Professor B. D. Schoub, Director of the. National Institute for Virology, was inadvertently omitted as the author of the obituary of Professor J. H. S. Gear published in the September 1994 SAMJ. Books.

  16. Maps of Relocation and Poems of Tang Dynasty Poets: Li Bai, Du Fu, and Han Yu

    Directory of Open Access Journals (Sweden)

    羅鳳珠、白璧玲、廖泫銘、范毅軍 、鄭錦全 Feng-Ju Lo,Pi-Ling Pai,Hsiung-Ming Liao,I-Chun Fan,Chin-Chuan Cheng

    2014-04-01

    Full Text Available Geographic environments affect literary contents and genre and thus, since ancient times, geographical area has been used to classify Chinese literature. In 1936 Liang Qichao was keenly aware of the relationship between literature and geography and brought up the idea of “literarygeography”. In 1979 Professor Chen Zhengxiang produced maps of birthplaces of Tang and Song poets to show the shift of Chinese cultural center from north to south. Furthermore, in the pastdecade, the attention to research in literary geography and geographical distribution of writersgradually increased. However, most studies focused on geographical distribution of birthplaces of writers and very few focused on the relationship between poets’ journey and the contents of their writings and their geographic environment. Meanwhile, geographic information system and aerialphotography have developed quickly and have become useful tools for the study of literary geography.Since then, the academic circles in Taiwan have built a solid foundation in this area. While Li Baiand Du Fu were called poetic immortal and poetic sage of the middle and end periods of the heydayof Tang Dynasty, respectively, Han Yu advocated the classical Chinese movement and becameone of the eight great authors of Tang and Song dynasties. Han Yu was also the best representative of Middle Tang poets. While the styles of these three poets differed from each other, they held key positions in the development and evolution of Tang poetry. Their footprints spread all over the countryand greatly affected later developments and contemporary of poetry. This project makes use of the digital Tang Dynasty maps by Tan Qixiang, Tang Dynasty transportation route maps by Yan Gengwang,aerial maps, the All Tang Poems, and chronicles of the poets to build the three poets’ relocation maps and study their poetic literature, language, geography, and interactions with others, in hopesof opening a new research direction

  17. Cardioprotective effects of Dan-Yang-Fu-Xin decoction on chronic ...

    African Journals Online (AJOL)

    Cardioprotective effects of Dan-Yang-Fu-Xin decoction on chronic heart failure in rats. ... including fractional shortening (FS), ejection fraction (EF), heart rate (HR) ... in body weight and increase in cardiac weight (p < 0.05) induced by CHF.

  18. Asynchronous Sensor fuSion for Improved Safety of air Traffic (ASSIST) Project

    Data.gov (United States)

    National Aeronautics and Space Administration — SSCI proposes to develop, implement and test a collision detection system for unmanned aerial vehicles (UAV), referred to as the Asynchronous Sensor fuSion for...

  19. The Australian Education Union's Response to Kevin Donnelly's "The Australian Education Union: A History of Opposing School Choice and School Autonomy Down-Under"

    Science.gov (United States)

    Hopgood, Susan

    2015-01-01

    This article is a response to Kevin Donnelly's article, "The Australian Education Union: A History of Opposing School Choice and School Autonomy Down-Under," and aims to correct specific errors and misrepresentations as found by Susan Hopgood, Federal Secretary of the Australian Education Union. She argues that the article is misleading…

  20. FuMicro: A Fused Microarchitecture Design Integrating In-Order Superscalar and VLIW

    Directory of Open Access Journals (Sweden)

    Yumin Hou

    2016-01-01

    Full Text Available This paper proposes FuMicro, a fused microarchitecture integrating both in-order superscalar and Very Long Instruction Word (VLIW in a single core. A processor with FuMicro microarchitecture can work under alternative in-order superscalar and VLIW mode, using the same pipeline and the same Instruction Set Architecture (ISA. Small modification to the compiler is made to expand the register file in VLIW mode. The decision of mode switch is made by software, and this does not need extra hardware. VLIW code can be exploited in the form of library function and the users will be exposed under only superscalar mode; by this means, we can provide the users with a convenient development environment. FuMicro could serve as a universal microarchitecture for it can be applied to different ISAs. In this paper, we focus on the implementation of FuMicro with ARM ISA. This architecture is evaluated on gem5, which is a cycle accurate microarchitecture simulation platform. By adopting FuMicro microarchitecture, the performance can be improved on an average of 10%, with the best performance improvement being 47.3%, compared with that under pure in-order superscalar mode. The result shows that FuMicro microarchitecture can improve Instruction Level Parallelism (ILP significantly, making it promising to expand digital signal processing capability on a General Purpose Processor.

  1. Interview with Professor Mark Wilcox.

    Science.gov (United States)

    Wilcox, Mark

    2016-08-01

    Mark Wilcox speaks to Georgia Patey, Commissioning Editor: Professor Mark Wilcox is a Consultant Microbiologist and Head of Microbiology at the Leeds Teaching Hospitals (Leeds, UK), the Professor of Medical Microbiology at the University of Leeds (Leeds, UK), and is the Lead on Clostridium difficile and the Head of the UK C. difficile Reference Laboratory for Public Health England (PHE). He was the Director of Infection Prevention (4 years), Infection Control Doctor (8 years) and Clinical Director of Pathology (6 years) at the Leeds Teaching Hospitals. He is Chair of PHE's Rapid Review Panel (reviews utility of infection prevention and control products for National Health Service), Deputy Chair of the UK Department of Health's Antimicrobial Resistance and Healthcare Associated Infection Committee and a member of PHE's HCAI/AR Programme Board. He is a member of UK/European/US working groups on C. difficile infection. He has provided clinical advice as part of the FDA/EMA submissions for the approval of multiple novel antimicrobial agents. He heads a healthcare-associated infection research team at University of Leeds, comprising approximately 30 doctors, scientists and nurses; projects include multiple aspects of C. difficile infection, diagnostics, antimicrobial resistance and the clinical development of new antimicrobial agents. He has authored more than 400 publications, and is the coeditor of Antimicrobial Chemotherapy (5th/6th/7th Editions, 15 December 2007).

  2. Formulation and investigation of 5-FU nanoparticles with factorial design-based studies.

    Science.gov (United States)

    Bozkir, Asuman; Saka, Ongun Mehmet

    2005-10-01

    This study describes an orthogonal experimental design to optimize the formulation of 5-fluorouracil (5-FU) loaded poly D,L (lactide-co-glycolide) (PLGA) nanoparticles (5FU-NP) by a nanoprecipitation-solvent displacement technique. The type of surfactant, amount of acetone and molecular weight of the polymer with three levels of each factor were selected and arranged in an L18(3(5)) orthogonal experimental table. From the statistical analysis of the data polynominal equations were generated. Optimized formulations have the particle size ranging from 160 to 250 nm. Smallest nanoparticles (161+/-1.22 nm) were obtained using Resomer PLGA 755 and pluronic F-68 with 10 ml acetone amount. Under these conditions the 5-FU entrapment percentage was maximum 78.30%, suggesting 5-FU might be entrapped and adsorbed on the nanoparticle surface. In vitro release of three formulations with maximum drug entrapment efficiency and minimum particle size, were also investigated by release kinetics. According to the determined coefficients, release data fit to Higuchi's diffusion kinetics. The in vitro release of 5FU-NP in phosphate buffered saline (PBS, pH 7.4) is suggested to be controlled by a combination of diffusion with slow and gradual erosion of the particles. Also, the antimicrobial activity was observed even on the end of seventh day with all formulations.

  3. Professor Gender, Age, and "Hotness" in Influencing College Students' Generation and Interpretation of Professor Ratings

    Science.gov (United States)

    Sohr-Preston, Sara L.; Boswell, Stefanie S.; McCaleb, Kayla; Robertson, Deanna

    2016-01-01

    A sample of 230 undergraduate psychology students rated their expectations of a bogus professor (who was randomly designated a man or woman and "hot" versus "not hot") based on ratings and comments found on RateMyProfessors.com. Five professor qualities were derived using principal components analysis: dedication,…

  4. Kung-fu versus swimming training and the effects on balance abilities in young adolescents.

    Science.gov (United States)

    Baccouch, Rym; Rebai, Haithem; Sahli, Sonia

    2015-11-01

    Our purpose is to investigate the static balance control of young adolescents practicing kung-fu and swimming in order to find out which of these physical activities is the most effective in developing specific balance abilities in young adolescents. Comparative experimental study. University laboratory research. Three groups of 11-13-year-old boys (12 practicing Kung-Fu, 12 practicing swimming and 12 controls). Center of pressure (CoP) excursions were registered in upright bipedal and unipedal stances on a stabilometric force platform in eyes open (EO) and eyes closed (EC) conditions. Kung-fu practitioners control their balance (P balance control in the EO condition. However, swimming training developed (P balance control in both EO and EC conditions. The swimmers showed a lower reliance on vision (P balance abilities that could be important for improving and maintaining optimal health. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. Overview of the Fusion Z-Pinch Experiment FuZE

    Science.gov (United States)

    Weber, T. R.; Shumlak, U.; Nelson, B. A.; Golingo, R. P.; Claveau, E. L.; McLean, H. S.; Tummel, K. K.; Higginson, D. P.; Schmidt, A. E.; UW/LLNL Team

    2016-10-01

    Previously, the ZaP device, at the University of Washington, demonstrated sheared flow stabilized (SFS) Z-pinch plasmas. Instabilities that have historically plagued Z-pinch plasma confinement were mitigated using sheared flows generated from a coaxial plasma gun of the Marshall type. Based on these results, a new SFS Z-pinch experiment, the Fusion Z-pinch Experiment (FuZE), has been constructed. FuZE is designed to investigate the scaling of SFS Z-pinch plasmas towards fusion conditions. The experiment will be supported by high fidelity physics modeling using kinetic and fluid simulations. Initial plans are in place for a pulsed fusion reactor following the results of FuZE. Notably, the design relies on proven commercial technologies, including a modest discharge current (1.5 MA) and voltage (40 kV), and liquid metal electrodes. Supported by DoE FES, NNSA, and ARPA-E ALPHA.

  6. Evolutionism through Chinese Eyes: Yan Fu, Ma Junwu and Their translations of Darwinian Evolutionism

    Directory of Open Access Journals (Sweden)

    Tsing-song Vincent Shen

    2015-04-01

    Full Text Available The huge impact that Darwinian Evolutionism has effected over Chinese intellectuals through Yan Fu's translation of Huxley's "Evolution and Ethics" into the Tianyanlun, is in fact based on Chinese traditional worldview on the one hand and the novel ideas it brings to the Chinese mind facing the challenge of transition. However, Yan Fu's translation is not as scientific as it should be when dealing with Huxley's discourse. Ma Junwu's translation of Darwin's "On the Origin of Species" attempts to be more scientific, in an effort to supply exact scientific terms and discourse in Chinese. However, at the end it is social Darwinism that has won the mind of the Chinese people. This paper analyses the ideas in Chinese past that leads to Chinese perception of Darwimism evolutionism and examines the ways it has been translated by Yan Fu and Ma Junwu.  

  7. 'Supermentoring' of assistant professors' teaching

    DEFF Research Database (Denmark)

    Lauridsen, Ole

    Aarhus University offers a mandatory pedagogical training program for assistant professors, required in order to obtain tenure at a Danish university. At Business and Social Sciences, this program is supplemented by voluntary observation and (first of all formative) supervision of the assistant...... professors’ teaching practice. This offer is given is (i) because many young university teachers face problems putting pedagogical theory into practice – even though the program mentioned is practice-oriented, and (ii) because many of them (partly due to (i)) lack self-confidence as to teaching....... The presentation will discuss the theoretical framework of the supervision given and compare it to other supervision models. Furthermore it will address the need of working with supervision in a SOTL context. Attendees will be activated through discussion of short prototypical cases. A possible – and desired...

  8. Observations on Professor Hayek's Plan

    Directory of Open Access Journals (Sweden)

    Ludwig von Mises

    2009-01-01

    Full Text Available This memorandum was written at the request of Henry Hazlitt to provide Mises’s comments on and concerns about F.A. Hayek’s initial proposals for what became the Mont Pèlerin Society. Mises stresses that those who favor liberty and freedom and oppose totalitarianism must also oppose interventionism. The memo argues that those who fought and lost against the rising tide of totalitarianism at the turn of the 20th Century lost their battles because they settled for middle-of-the-road policies that conceded considerable ground to the socialists. The weak point in Professor Hayek’s plan is that it relies upon the cooperation of many men who are today’s middle-of-the-roaders. As interventionists, they may not be the hoped-for intellectual pioneers to inspire people to build a freer world.

  9. Professor Camillo Negro's Neuropathological Films.

    Science.gov (United States)

    Chiò, Adriano; Gianetto, Claudia; Dagna, Stella

    2016-01-01

    Camillo Negro, Professor in Neurology at the University of Torino, was a pioneer of scientific film. From 1906 to 1908, with the help of his assistant Giuseppe Roasenda and in collaboration with Roberto Omegna, one of the most experienced cinematographers in Italy, he filmed some of his patients for scientific and educational purposes. During the war years, he continued his scientific film project at the Military Hospital in Torino, filming shell-shocked soldiers. In autumn 2011, the Museo Nazionale del Cinema, in partnership with the Faculty of Neurosciences of the University of Torino, presented a new critical edition of the neuropathological films directed by Negro. The Museum's collection also includes 16 mm footage probably filmed in 1930 by Doctor Fedele Negro, Camillo's son. One of these films is devoted to celebrating the effects of the so-called "Bulgarian cure" on Parkinson's disease.

  10. How College Students View a Professor's Role

    Science.gov (United States)

    Gadzella, Bernadette M.

    1977-01-01

    Views of 3,670 students from six colleges and universities on most and least important traits of an ideal professor were analyzed. All data were collected with the same instrument. Data revealed students selected similar MOST and LEAST important traits of a quality professor. (Author)

  11. Finnish Students' Perceptions of a Visiting Professor.

    Science.gov (United States)

    Haussler, Susan C.; Paavilainen, Eija; Astedt-Kurki, Paivi

    2003-01-01

    Finnish nursing students (n=31) evaluated their experience with a visiting Fulbright professor. Students were satisfied with course content, teaching methods, and information about the U.S. health care system. They thought the professor should have been more knowledgeable about Finnish culture, education, and health care. (Contains 15 references.)…

  12. Professor Delight: Cultivating Organizational Citizenship Behavior

    Science.gov (United States)

    Mazen, Abdelmagid; Herman, Susan; Ornstein, Suzyn

    2008-01-01

    This article describes the rationale for and use of a class innovation the authors call "professor delight." This inexpensive, high-yield concept allows students and professors to enact their understanding of citizenship throughout the term, and often beyond. The authors explain the concept, describe its implementation in class, and link it to the…

  13. MTHFR polymorphisms and 5-FU-based adjuvant chemotherapy in colorectal cancer

    DEFF Research Database (Denmark)

    Afzal, Shoaib; Jensen, S; Vainer, B

    2009-01-01

    >T and 1298A>C polymorphisms were not associated with survival or relapse-free survival (P > 0.2). The 677 CC genotype was associated to toxicity (odds ratio = 1.83, P = 0.01). Conclusions: The MTHFR 677C>T and 1298A>C polymorphisms probably do not predict efficacy of adjuvant 5-FU treatment in colorectal...... cancer after complete resection; however, the 677C>T polymorphism may be associated with lower toxicity in 5-FU treatment. Implementation of SNP analysis for these polymorphisms for individualized treatment is premature....

  14. Wheat germ allutinin functionalized crosslinked polyelectrolyte microparticles for local colon delivery of 5-FU

    DEFF Research Database (Denmark)

    Glavas-Dodov, Marija; Steffansen, Bente; Crcarevska, Maja

    2013-01-01

    We have previously reported the development and characterisation of wheat germ agglutinin (WGA)-functionalised chitosan-Ca-alginate (CTS-Ca-ALG) microparticles (MPs) loaded with acid-resistant particles of 5-fluorouracil (5-FU). In the present work, our goal was to evaluate the potential of these......We have previously reported the development and characterisation of wheat germ agglutinin (WGA)-functionalised chitosan-Ca-alginate (CTS-Ca-ALG) microparticles (MPs) loaded with acid-resistant particles of 5-fluorouracil (5-FU). In the present work, our goal was to evaluate the potential...

  15. A long-term photometric study of the FU Orionis star V 733 Cep

    OpenAIRE

    Peneva, S. P.; Semkov, E. H.; Munari, U.; Birkle, K.

    2010-01-01

    The FU Orionis candidate V733 Cep was discovered by Roger Persson in 2004. The star is located in the dark cloud L1216 close to the Cepheus OB3 association. Because only a small number of FU Orionis stars have been detected to date, photometric and spectral studies of V733 Cep are of great interest. The studies of the photometrical variability of PMS stars are very important to the understanding of stellar evolution. The main purpose of our study is to construct a long-time light curve of V73...

  16. Final Scientific/Technical Report for project “Geomechanical Monitoring for CO2 Hub Storage: Production and Injection at Kevin Dome

    Energy Technology Data Exchange (ETDEWEB)

    Daley, Thomas M. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Vasco, Don [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Ajo-Franklin, Jonathan [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Dobeck, Laura [Montana State Univ., Bozeman, MT (United States); Spangler, Lee [Montana State Univ., Bozeman, MT (United States); Leonti, Michelle [Montana State Univ., Bozeman, MT (United States)

    2017-06-27

    After learning that the TDS value in the target injection formation at the Kevin Dome site is too low to qualify for an EPA Class VI CO2 injection permit, the BSCSP project was re-scoped such that injection of CO2 is no longer planned. With no injection planned, the Geomechanics project was closed. In this final report, we describe the objective and approach of the project as proposed, and the limited results obtained before stopping work. The objective of the proposed research was the development & validation of an integrated monitoring approach for quantifying the interactions between large-scale geological carbon storage (GCS) and subsurface geomechanical state, particularly perturbations relevant to reservoir integrity such as fault reactivation and induced fracturing. In the short period of work before knowing the fate of the Kevin Dome project, we (1) researched designs for both the proposed InSAR corner reflectors as well as the near-surface 3C seismic stations; (2) developed preliminary elastic geomechanical models; (3) developed a second generation deformation prediction for the BSCSP Kevin Dome injection site; and (4) completed a preliminary map of InSAR monuments and shallow MEQ wells in the vicinity of the BSCSP injection pad.

  17. Memorial to Professor Antonio Barone

    Science.gov (United States)

    Tafuri, Francesco; Pepe, Giampiero; Vaglio, Ruggero

    2014-04-01

    Antonio Barone prematurely passed away on 4 December 2011 at the age of 72, after a one-year battle with cancer. He left behind his wife Sveva and his two sons, Alberto and Livio. Antonio was Professor Emeritus at the University of Napoli Federico II, where he had been teaching for about 40 years. The initial research activity of Antonio was in the field of nuclear physics. In this context, almost 45 years ago, the Ge 'Lithium drift' semiconductor detectors represented a novelty, due to the high energy resolution enabled by those devices. Superconductors stimulated new approaches to radiation detection and this motivated Antonio's interest towards superconductivity. Following the birth of the Laboratorio di Cibernetica of the CNR in 1967 he was given the opportunity to work on a joint USA-Italy project (University of Wisconsin, Madison and CNR Naples) in the field of superconductivity on the peculiar subject of the superconductive 'Neuristors'. His research activity on Josephson junctions opened up a wide variety of very stimulating subjects in which he was deeply involved, ranging from the soliton propagation in 'long' Josephson structures to fluctuations phenomena, from light-sensitive junctions and proximity effect to the development of innovative superconducting devices. The strong interaction of Antonio with the Landau Institute for Theoretical Physics of the Academy of Sciences in Moscow, characterizes a long period of his research activity with a precious merging of theoretical and experimental aspects. This body of work converged into the famous monograph on the 'Physics and Applications of the Josephson Effect', written in collaboration with Gianfranco Paternò in 1982. This rapidly became the reference text for the Josephson effect, as documented by thousands of citations and the fact that it was translated into Russian, Japanese and Chinese. In 1983 Antonio was awarded the highest academic title of 'Doctor of the Physical-Mathematical Sciences' by the

  18. Attenuated Cardiac Mitochondrial-Dependent Apoptotic Effects by Li-Fu Formula in Hamsters Fed with a Hypercholesterol Diet

    Directory of Open Access Journals (Sweden)

    Wei-Wen Kuo

    2011-01-01

    Full Text Available Apoptosis involves in the pathogenesis of various cardiac abnormalities. This study intends to evaluate the effects of Li-Fu formula on cardiac apoptosis induced by hyper-cholesterol diet. Twenty-four male Golden Syrian hamsters were randomly divided into Control, Cholesterol and Li-Fu formula groups. Histopathological analysis, western blotting and terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL assays were performed to measure the effects of Li-Fu formula on left ventricle. Significantly reduced TUNEL-positive cells and mitochondria- dependent apoptosis were observed in the left ventricle of hamsters from Li-Fu formula group compared to the Cholesterol group. Additionally, induced cardiac insulin like growth factor I receptor (IGFIR-dependent survival pathway was detected in the Li-Fu formula group compared to the Cholesterol group. Besides, minor fibrosis, increased collagen deposition, and myofibril disarray was detected in the Cholesterol group, whereas the reductions of collagen deposition and myofibril disarray were observed in the Li-Fu formula group. This study demonstrated that Li-Fu formula not only reduced the mitochondria-dependent apoptosis and fibrosis, but also enhanced the IGF-I survival pathway in the left ventricle from high cholesterol-fed hamsters. We suggest the protective effects of Li-Fu formula on cardiac apoptosis and therapeutic potentials against cardiovascular disease.

  19. FuMa: reporting overlap in RNA-seq detected fusion genes.

    Science.gov (United States)

    Hoogstrate, Youri; Böttcher, René; Hiltemann, Saskia; van der Spek, Peter J; Jenster, Guido; Stubbs, Andrew P

    2016-04-15

    A new generation of tools that identify fusion genes in RNA-seq data is limited in either sensitivity and or specificity. To allow further downstream analysis and to estimate performance, predicted fusion genes from different tools have to be compared. However, the transcriptomic context complicates genomic location-based matching. FusionMatcher (FuMa) is a program that reports identical fusion genes based on gene-name annotations. FuMa automatically compares and summarizes all combinations of two or more datasets in a single run, without additional programming necessary. FuMa uses one gene annotation, avoiding mismatches caused by tool-specific gene annotations. FuMa matches 10% more fusion genes compared with exact gene matching due to overlapping genes and accepts intermediate output files that allow a stepwise analysis of corresponding tools. The code is available at: https://github.com/ErasmusMC-Bioinformatics/fuma and available for Galaxy in the tool sheds and directly accessible at https://bioinf-galaxian.erasmusmc.nl/galaxy/ y.hoogstrate@erasmusmc.nl or a.stubbs@erasmusmc.nl Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  20. Cardioprotective effects of Dan-Yang-Fu-Xin decoction on chronic ...

    African Journals Online (AJOL)

    Purpose: To evaluate the cardioprotective effects and possible mechanisms of Dan-Yang-Fu-Xin decoction (DYFX) in a rat chronic heart failure (CHF). Methods: A CHF rat model induced by ligation of the left anterior descending coronary artery was used to investigate the cardioprotective effects of DYFX. After intragastric ...

  1. Variability of OI 090.4 ShaoMing Hu , Xu Chen & DiFu Guo

    Indian Academy of Sciences (India)

    2009-12-20

    Dec 20, 2009 ... ShaoMing Hu. ∗. , Xu Chen & DiFu Guo. School of Space Science and Physics, Shandong University, Weihai,. 180 Cultural West Road, Shandong 264209, China. ∗ e-mail: husm@sdu.edu.cn. Abstract. OI 090.4 was monitored on 21 nights from 2006 to 2012 for studying the variability. Strong variations ...

  2. Fungal community succession and major components change during manufacturing process of Fu brick tea.

    Science.gov (United States)

    Li, Qin; Huang, Jianan; Li, Yongdi; Zhang, Yiyang; Luo, Yu; Chen, Yuan; Lin, Haiyan; Wang, Kunbo; Liu, Zhonghua

    2017-07-31

    Fu brick tea is a unique post-fermented tea product which is fermented with microorganism during the manufacturing process. Metabolic analysis showed that most metabolites content were decreased during the manufacturing process of Fu brick tea, except GA (gallic acid). Illumina MiSeq sequencing of ITS gene amplicons was applied to analyze the fungal community succession. The genera Aspergillus, Cyberlindnera and Candida were predominant at the early stage of manufacturing process (from "primary dark tea" to "fermentation for 3 days"), but after the stage of "fermentation for 3 days" only Aspergillus was still dominated, and maintain a relatively constant until to the end of manufacturing process. The effects of metabolites on the structure of the fungal community were analyzed by redundancy analysis (RDA) and variation partitioning analysis (VPA). The results indicated that GCG (gallocatechin gallate), EGCG (epigallocatechin gallate) and GA as well as the interactions among them were the most probably ones to influence, or be influenced by the fungal communities during the fermentation process of Fu brick tea. This study revealed fungal succession, metabolite changes and their relationships, provided new insights into the mechanisms for manufacturing process of Fu brick tea.

  3. *J.S., Ogeh and E. Ukodo Fu ll L eng th R esearch A rticle

    African Journals Online (AJOL)

    can also make a basis for defining different management zones on a field or an area. Based on the above the objective of this work was to examine the variability of some soil physical and chemical properties from three (3) pedons, in a toposequence in the University of Benin, Edo State, Nigeria. Fu ll L eng th. R esearch. A.

  4. [Mining analysis on composition and medication of menstruation prescriptions in Fu Qingzhu's Obstetrics and Gynecology].

    Science.gov (United States)

    Zhu, Jia-qing; Che, Yu-xia

    2015-04-01

    In this paper, menstruation prescriptions were selected from "Fu Qingzhu's Obstetrics and Gynecology" and analyzed by using GRI algorithm, correlation analysis, hierarchical clustering method through SPSS, Clementine and traditional Chinese medicine (TCM) inheritance auxiliary systems, in order to screen out 15 menopathy prescriptions, which involve 45 traditional Chinese medicine herbs. In the study, blood-tonifying and qi-tonifying herbs were found to be frequent in the prescriptions. The most frequent single herb was white paeony root, accounting for 9.6% in the total number of prescriptions; The most frequent herb pairs were white paeony root-radix rehmanniae preparata and paeony root-angelica sinensis. Among Fu Shan's menopathy prescriptions, 61 herbal pairs showed a correlation coefficient exceeding 0.05, which evolved into 16 pairs of core combinations. The analysis showed that menopathy prescriptions in volume 1 of "Fu Qingzhu's Obstetrics and Gynecology" focused on tonic traditional Chinese medicines involving liver, spleen and kidney and were adjusted according to changes in qi, blood, cold, hot and wet, which could provide a specific reference for further studies on Fu Shan's academic thoughts and traditional Chinese medicine clinical treatment of menopathy.

  5. Nanomeditsiin / Kevin Bullis

    Index Scriptorium Estoniae

    Bullis, Kevin

    2006-01-01

    Michigani ülikooli arstiteadlane James Baker loob nanoosakesi medikamentide juhtimiseks otse vähirakkudesse, mis võib kaasa tuua palju ohutuma ravi. Artikkel üldpealkirja all: 10 tulevikutehnoloogiat

  6. Kevin: A Visualiser Pupil.

    Science.gov (United States)

    Cruz, Ines; Febles, Maria; Diaz, Jose

    2000-01-01

    Presents a case study that aimed to obtain information on students' mathematical comprehension levels and on whether students may or may not make use of visualization processes in solving mathematical problems. Discovers students' beliefs about teaching and learning processes in general, and mathematics in particular. (Contains 25 references.)…

  7. PROFESSORES: IMAGENS DO FUTURO PRESENTE

    Directory of Open Access Journals (Sweden)

    Maitê Alves Bezerra

    2014-06-01

    Full Text Available Ao observar a comunidade portuguesa que busca compreender a historicidade das formas e dos processos de escolarização por meio do estabelecimento de intenso diálogo com outras comunidades, é impossível não dar destaque à figura de António Manuel Seixas Nóvoa. Nascido em Lisboa no ano de 1954, aos 18 anos inicia o curso de Ciências da Educação na Universidade de Lisboa. Após lecionar em importantes universidades tais como Paris V, Oxford e Columbia University, atualmente acumula as posições de reitor da Universidade de Lisboa e professor catedrático da Faculdade de Psicologia e de Ciências da Educação na Instituição. Nóvoa tem se destacado à frente de debates internacionais a respeito da história da educação e educação comparada.

  8. Protective effect of dexamethasone on 5-FU-induced oral mucositis in hamsters.

    Directory of Open Access Journals (Sweden)

    Susana Barbosa Ribeiro

    Full Text Available Oral mucositis (OM is an important side effect of cancer treatment, characterized by ulcerative lesions in the mucosa of patients undergoing radiotherapy or chemotherapy, which has marked effects on patient quality of life and cancer therapy continuity. Considering that few protocols have demonstrated efficacy in preventing this side effect, the aim of this study was to examine the effect of dexamethasone (DEX on OM induced by 5-fluorouracil (5-FU in hamsters by studying signaling pathways. OM was induced in hamsters by 5-FU followed by mechanical trauma (MT on day 4. On day 10, the animals were euthanized. The experimental groups included saline, MT, 5-FU, and DEX (0.25, 0.5, or 1 mg/kg. Macroscopic, histopathological, and immunohistochemical analyses as well as immunofluorescence experiments were performed on the oral mucosa of the animals. The oral mucosal samples were analyzed by enzyme-linked immunosorbent assays, and quantitative real-time polymerase chain reaction (qPCR. DEX (0.5 or 1 mg/kg reduced inflammation and ulceration of the oral mucosa of hamsters. In addition, DEX (1 mg/kg reduced the cytokine levels of tumor necrosis factor (TNF-α, interleukin (IL-1β, and macrophage migration inhibitory factor (MIF. DEX (1 mg/kg also reduced the immunoexpression of cyclooxygenase (COX-2, matrix metalloproteinase (MMP-2, transforming growth factor (TGF-β, MIF, Smad 2/3, Smad 2/3 phosphorylated and NFκB p65 in the jugal mucosa. Finally, DEX (1 mg/kg increased interleukin-1 receptor-associated kinase 3 (IRAK-M, glucocorticoid-induced leucine zipper (GILZ, and mitogen-activated protein kinase (MKP1 gene expression and reduced NFκB p65 and serine threonine kinase (AKt gene expression, relative to the 5-FU group. Thus, DEX improved OM induced by 5-FU in hamsters.

  9. Protective effect of dexamethasone on 5-FU-induced oral mucositis in hamsters.

    Science.gov (United States)

    Ribeiro, Susana Barbosa; de Araújo, Aurigena Antunes; Araújo Júnior, Raimundo Fernandes de; Brito, Gerly Anne de Castro; Leitão, Renata Carvalho; Barbosa, Maisie Mitchele; Garcia, Vinicius Barreto; Medeiros, Aldo Cunha; Medeiros, Caroline Addison Carvalho Xavier de

    2017-01-01

    Oral mucositis (OM) is an important side effect of cancer treatment, characterized by ulcerative lesions in the mucosa of patients undergoing radiotherapy or chemotherapy, which has marked effects on patient quality of life and cancer therapy continuity. Considering that few protocols have demonstrated efficacy in preventing this side effect, the aim of this study was to examine the effect of dexamethasone (DEX) on OM induced by 5-fluorouracil (5-FU) in hamsters by studying signaling pathways. OM was induced in hamsters by 5-FU followed by mechanical trauma (MT) on day 4. On day 10, the animals were euthanized. The experimental groups included saline, MT, 5-FU, and DEX (0.25, 0.5, or 1 mg/kg). Macroscopic, histopathological, and immunohistochemical analyses as well as immunofluorescence experiments were performed on the oral mucosa of the animals. The oral mucosal samples were analyzed by enzyme-linked immunosorbent assays, and quantitative real-time polymerase chain reaction (qPCR). DEX (0.5 or 1 mg/kg) reduced inflammation and ulceration of the oral mucosa of hamsters. In addition, DEX (1 mg/kg) reduced the cytokine levels of tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and macrophage migration inhibitory factor (MIF). DEX (1 mg/kg) also reduced the immunoexpression of cyclooxygenase (COX)-2, matrix metalloproteinase (MMP)-2, transforming growth factor (TGF)-β, MIF, Smad 2/3, Smad 2/3 phosphorylated and NFκB p65 in the jugal mucosa. Finally, DEX (1 mg/kg) increased interleukin-1 receptor-associated kinase 3 (IRAK-M), glucocorticoid-induced leucine zipper (GILZ), and mitogen-activated protein kinase (MKP1) gene expression and reduced NFκB p65 and serine threonine kinase (AKt) gene expression, relative to the 5-FU group. Thus, DEX improved OM induced by 5-FU in hamsters.

  10. Long-Wavelength Excesses of FU Orionis Objects: Flared Outer Disks or Infalling Envelopes?

    Science.gov (United States)

    Zhu, Zhaohuan; Hartmann, Lee; Calvet, Nuria; Hernandez, Jesus; Tannirkulam, Ajay-Kumar; D'Alessio, Paola

    2008-09-01

    The mid- to far-infrared emission of the outbursting FU Orionis objects has been attributed either to a flared outer disk or to an infalling envelope. We revisit this issue using detailed radiative transfer calculations to model the recent, high signal-to-noise ratio data from the IRS instrument on the Spitzer Space Telescope. In the case of FU Ori, we find that a physically plausible flared disk irradiated by the central accretion disk matches the observations. Building on our previous work, our accretion disk model with outer disk irradiation by the inner disk reproduces the spectral energy distribution between ~4000 Å and ~40 μm. Our model is consistent with near-infrared interferometry, but there are some inconsistencies with mid-infrared interferometric results. Including the outer disk allows us to refine our estimate of the outer radius of the outbursting, high mass accretion rate disk in FU Ori as ~0.5 AU, which is a crucial parameter in assessing theories of the FU Orionis phenomenon. We are able to place an upper limit on the mass infall rate of any remnant envelope infall rate to ~7 × 10-7 M⊙ yr -1 assuming a centrifugal radius of 200 AU. The FUor BBW 76 is also well modeled by a 0.6 AU inner disk and a flared outer disk. However, V1515 Cyg requires an envelope with an outflow cavity to adequately reproduce the IRS spectrum. In contrast with the suggestion by Green et al., we do not require a flattened envelope to match the observations; the inferred cavity shape is qualitatively consistent with typical protostellar envelopes. This variety of dusty structures suggests that the FU Orionis phase can be present at either early or late stages of protostellar evolution.

  11. Professor dr hab. Anna Maria Bujakiewicz

    Directory of Open Access Journals (Sweden)

    Anna Kujawa

    2015-08-01

    Full Text Available The article presents the biography and scientific achievements of Professor Anna Bujakiewicz. After receiving her master’s degree and doctorate in biology and mycology from Adam Mickiewicz University in Poznań, Professor Bujakiewicz continued her exciting research and teaching on mycology at her Alma Mater Posnaniensis for more than 50 years. Her publications in this field include many books, articles, and other scholarly reports.

  12. Differences between Male Students' and Female Students' Perception of Professors

    Science.gov (United States)

    Tomkiewicz, Joseph; Bass, Kenneth

    2008-01-01

    This study is an empirical examination of possible differences between female and male college seniors' perceptions between male and female college professors. Subjects were presented with three variations of a scale designed to measure students' perceptions of university professors in general, female professors, and male professors. These…

  13. Effects of combination therapy with vesnarinone, 5-FU and radiation on growth of human pancreatic cancer xenografts in nude mice

    Energy Technology Data Exchange (ETDEWEB)

    Takamura, Michio; Nio, Yoshinori; Minari, Yoshimitsu; Iguchi, Chikage; Sasaki, Susumu; Hirahara, Noriyuki; Tamura, Katsuhiro [Shimane Medical Univ., Izumo (Japan)

    1999-01-01

    We examined the combination effect of Vesnarinone (AZ, 5 mg/day), 5-FU (40 mg/kg) and radiation (RT, 8 Gy/body) for human pancreatic cancer lines which were subcutaneously xenografted in nude mice. AZ alone did not inhibit their growth, but a combination of AZ, 5-FU and RT showed a significant inhibition. Pathological study demonstrated that the ductal structure became more prominent in the poorly differentiated tumors after Vesnarinone treatment. In conclusion, vesnarinone may be a beneficial agent for the differentiation therapy of pancreatic cancer, especially in combination with 5-FU and/or RT. (author)

  14. Accounting Professor Qualification in Digital Age: A Perception Study on Brazilian Professors

    Science.gov (United States)

    Vendruscolo, Maria Ivanice; Behar, Patrícia Alejandra

    2015-01-01

    This papers aims at analyzing the perception of Accounting professors about the necessary qualifications in Accounting undergraduate courses. The contribution of this study is to theoretically discuss the education of Accounting professors, with empirical data, because Accounting teaching requires specific competencies in the digital area. The…

  15. The Akt inhibitor ISC-4 synergizes with cetuximab in 5-FU-resistant colon cancer.

    Directory of Open Access Journals (Sweden)

    Joshua E Allen

    Full Text Available Phenylbutyl isoselenocyanate (ISC-4 is an Akt inhibitor with demonstrated preclinical efficacy against melanoma and colon cancer. In this study, we sought to improve the clinical utility of ISC-4 by identifying a synergistic combination with FDA-approved anti-cancer therapies, a relevant and appropriate disease setting for testing, and biomarkers of response. We tested the activity of ISC-4 and 19 FDA-approved anticancer agents, alone or in combination, against the SW480 and RKO human colon cancer cell lines. A synergistic interaction with cetuximab was identified and validated in a panel of additional colon cancer cell lines, as well as the kinetics of synergy. ISC-4 in combination with cetuximab synergistically reduced the viability of human colon cancer cells with wild-type but not mutant KRAS genes. Further analysis revealed that the combination therapy cooperatively decreased cell cycle progression, increased caspase-dependent apoptosis, and decreased phospho-Akt in responsive tumor cells. The synergism between ISC-4 and cetuximab was retained independently of acquired resistance to 5-FU in human colon cancer cells. The combination demonstrated synergistic anti-tumor effects in vivo without toxicity and in the face of resistance to 5-FU. These results suggest that combining ISC-4 and cetuximab should be explored in patients with 5-FU-resistant colon cancer harboring wild-type KRAS.

  16. The housekeeper and the professor a novel

    CERN Document Server

    Ogawa, Yoko

    2010-01-01

    He is a brilliant math Professor with a peculiar problem—ever since a traumatic head injury, he has lived with only eighty minutes of short-term memory. She is an astute young Housekeeper—with a ten-year-old son—who is hired to care for the Professor. And every morning, as the Professor and the Housekeeper are introduced to each other anew, a strange and beautiful relationship blossoms between them. Though he cannot hold memories for long (his brain is like a tape that begins to erase itself every eighty minutes), the Professor's mind is still alive with elegant equations from the past. And the numbers, in all of their articulate order, reveal a sheltering and poetic world to both the Housekeeper and her young son. The Professor is capable of discovering connections between the simplest of quantities—like the Housekeeper's shoe size—and the universe at large, drawing their lives ever closer and more profoundly together, even as his memory slips away. Yoko Ogawa's The Housekeeper and the Professo...

  17. I Am the Invincible Sword Goddess: Mediatization of Chinese Gender Ideology through Female Kung-Fu Practitioners in Films

    National Research Council Canada - National Science Library

    Mie Hiramoto; Cherise Shi Ling Teo

    2014-01-01

    .... In this paper, we investigate representations of female kung-fu practitioners (nuxia) in films to discuss how processes of mediation and mediatization depict their femininity, so as to mitigate their appropriation of Chinese martial arts masculinity...

  18. Cell Line Derived 5-FU and Irinotecan Drug-Sensitivity Profiles Evaluated in Adjuvant Colon Cancer Trial Data

    DEFF Research Database (Denmark)

    Buhl, Ida Kappel; Gerster, Sarah; Delorenzi, Mauro

    2016-01-01

    patients enrolled in the PETACC-3 prospective randomized clinical trial. A 5-FU profile developed similarly was assessed by comparing the PETACC-3 cohort with a cohort of 359 stage II colon cancer patients who underwent surgery but received no adjuvant therapy. RESULTS: There was no statistically...... patients who benefitted from the addition of irinotecan to 5-FU, we used gene expression profiles based on cell lines and clinical tumor material. These profiles were applied to expression data obtained from pretreatment formalin fixed paraffin embedded (FFPE) tumor tissue from 636 stage III colon cancer...... to identify colon cancer patients who may benefit from 5-FU, however, any biomarker predicting benefit for adjuvant 5-FU must be rigorously evaluated in independent cohorts. Given differences between the two study cohorts, the present results should be further validated....

  19. Professor Karel Oštir zum andenken

    Directory of Open Access Journals (Sweden)

    Bojan Čop

    1973-12-01

    Full Text Available Die Redaktion der Zeitschrift tinguistica beschloss am Anfang des Jahres 1973, den XIII.Jg. der Vollendung des fünfundachtzigsten Lebensjahres, die Professor Karel Oštir am 13. Oktober feiern sollte, zu widmen. Da sich aber das Sammeln des Materials für diesen Jahrgang sowie der Druck des XII. Jahrganges allzusehr in die Länge gezogen hatten, ist uns das unerbittliche Schicksal zuvorgekommen: am 27. Dezember 1973 ist Professor Karel Oštir sanft entschlafen. Das Leben eines der eigenartigsten Sprachwissenschaftler aller Zei ten hat sich so erfüllt. Aus einer Festschrift musste nun eine Gedenkschrift werden.

  20. Professor Stewart's casebook of mathematical mysteries

    CERN Document Server

    Stewart, Ian

    2014-01-01

    Like its wildly popular predecessors Cabinet of Mathematical Curiosities and Hoard of Mathematical Treasures, Professor Stewart's brand-new book is a miscellany of over 150 mathematical curios and conundrums, packed with trademark humour and numerous illustrations. In addition to the fascinating formulae and thrilling theorems familiar to Professor Stewart's fans, the Casebook follows the adventures of the not-so-great detective Hemlock Soames and his sidekick Dr John Watsup (immortalised in the phrase 'Watsup, Doc?'). By a remarkable coincidence they live at 222B Baker Street, just a

  1. GRP78 confers the resistance to 5-FU by activating the c-Src/LSF/TS axis in hepatocellular carcinoma.

    Science.gov (United States)

    Gu, Yan-jiao; Li, Hong-dan; Zhao, Liang; Zhao, Song; He, Wu-bin; Rui, Li; Su, Chang; Zheng, Hua-chuan; Su, Rong-jian

    2015-10-20

    5-FU is a common first-line chemotherapeutic drug for the treatment of hepatocellular carcinoma. However the development of acquired resistance to 5-FU confines its clinical usages. Although this phenomenon has been the subject of intense investigation, the exact mechanism of acquired resistance to 5-FU remains elusive. Here, we report that over-expression of GRP78 contributes to acquired resistance to 5-FU in HCC by up-regulating the c-Src/LSF/TS axis. Moreover, we found that the resistance to 5-FU conferred by GRP78 is mediated by its ATPase domain. The ATPase domain differentially increased the expression of LSF, TS and promoted the phosphorylation of ERK and Akt. We further identified that GRP78 interacts physically with c-Src through its ATPase domain and promotes the phosphorylation of c-Src, which in turn increases the expression of LSF in the nucleus. Together, GRP78 confers the resistance to 5-FU by up-regulating the c-Src/LSF/TS axis via its ATPase domain.

  2. Kai Adolf Jensen, professor i almindelig patologi

    DEFF Research Database (Denmark)

    Høiby, Niels

    2016-01-01

    for the Bacillus Calmette-Guérin vaccine production and supervised many young scientists’ doctoral theses on the aspects of tuberculosis. He became internationally recognized, and he revealed an important scientific fraud in the laboratory of the Austrian professor Ernst Löwenstein (1878-1950), who claimed that he...

  3. String theorist takes over as Lucasian Professor

    Science.gov (United States)

    Banks, Michael

    2009-11-01

    String theorist Michael Green will be the next Lucasian Professor of Mathematics at Cambridge University. Green, 63, will succeed Stephen Hawking, who held the chair from 1980 before retiring last month at the age of 67 and taking up a distinguished research chair at the Perimeter Institute for Theoretical Physics in Canada (see above).

  4. Epistemology Shock: English Professors Confront Science

    Science.gov (United States)

    Barnard, Ian; Osborn, Jan

    2017-01-01

    This article raises questions and concerns regarding students from the sciences working with faculty in the humanities in interdisciplinary settings. It explores the experience of two English professors facing the privileging of "facts" and a science-based understanding of the world in their own classrooms. It poses both questions and…

  5. Understanding Asperger Syndrome: A Professor's Guide [DVD

    Science.gov (United States)

    Organization for Autism Research (NJ3), 2011

    2011-01-01

    College can be a trying time in any individual's life. For adults with Asperger Syndrome this experience can be overwhelming. This title in the new DVD series Asperger Syndrome and Adulthood focuses on educating professors, teaching assistants, and others on what it means to be a college student on the spectrum and how they might best be able to…

  6. Professor Brand Advocacy: Do Brand Relationships Matter?

    Science.gov (United States)

    Jillapalli, Ravi K.; Wilcox, James B.

    2010-01-01

    The trend among students to advocate their professors online continues to generate interest within marketing academia. Brand advocacy in products and services has played a vital role in marketing. However, no known research to date has embraced the idea of brand advocacy in marketing education. This research builds on the recent human brand…

  7. Forestry professors and students receive national recognition

    OpenAIRE

    Davis, Lynn

    2005-01-01

    Two Virginia Tech professors in the College of Natural Resources and the university's Society of American Foresters student chapter received awards for their accomplishments at the Society of American Foresters 2005 national convention held in Fort Worth, Texas, earlier this month.

  8. Two business professors receive Fulbright Scholar awards

    OpenAIRE

    Ho, Sookhan

    2005-01-01

    Virginia Tech Pamplin College of Business professors Larry French and Mahmood A. Khan have received Fulbright Scholar Awards to teach and conduct research abroad next year. Both faculty members teach in the MBA program at the university's Northern Virginia Center in metro Washington, D.C.

  9. The Supervisor Is Not the Professor

    Science.gov (United States)

    Johnson, G. Stewart; Shafer, Carl

    1970-01-01

    College educational exposure does not prepare the graduate for the human relations demands of teamwork in industry, and may not prepare the graduate for the relationship with his supervisor. Five major dimensions of difference for the student between his interaction with his professors and his new relationships with his supervisor are: degree of…

  10. "Dear Professor: I Hate You"--Anonymous

    Science.gov (United States)

    Bartlett, Thomas

    2009-01-01

    Flip through a stack of anonymous student evaluations of professors and the mild comments, even the compliments, tend to blend together. But often, hidden among them, is a dagger. Then there are the out-and-out insults. Students' comments can be more than simply mean. Sometimes student comments aren't cruel, just weird. In this article, some…

  11. Africa's New Crisis: A Dearth of Professors

    Science.gov (United States)

    Lindow, Megan

    2009-01-01

    With many professors approaching retirement. a shortage of qualified academics has reached crisis proportions at a number of African universities. The shortfall is a consequence of decades of neglect of African higher education, as donors and governments concentrated limited resources on primary and secondary schools, and young scholars who manage…

  12. Professor Jacques Cortes prantsuse keele lektoraadis

    Index Scriptorium Estoniae

    2000-01-01

    Juuni alguses külastas filoloogiateaduskonna romaani-germaani filoloogia osakonda Roueni ülikooli professor Jacques Cortes (Prantsusmaa). Ta korraldas 4. õa üliõpilastele prantsuse keele intensiivkursuse ja võttis vastu eksami ning kohtus prantsuse keele lektoraadi õppejõududega : [täistekst

  13. Microcomputing Competencies for Special Education Professors.

    Science.gov (United States)

    Blackhurst, A. Edward; And Others

    1987-01-01

    A list of microcomputing competencies associated with functions that special education professors typically perform was assessed by 148 special education faculty who use microcomputers. Word processing was rated as the single most useful competency, along with the category of providing instruction about microcomputer applications in special…

  14. Veterinary medicine professor receives national honor

    OpenAIRE

    Douglas, Jeffrey S.

    2005-01-01

    Marie-Suthers-McCabe, of Riner, Va., associate professor of small animal clinical sciences at the Virginia-Maryland Regional College of Veterinary Medicine, has been awarded the highest honor in the nation for work in the area of the "human/animal bond."

  15. CFA or CFP: A Guide for Professors

    Science.gov (United States)

    Moy, Ronald L.

    2011-01-01

    The CFA Institute and the CFP Board of Standards provide professional certifications in the field of finance. In this paper, I provide my experience with the CFA and CFP programs in order to give other professors some insight into the process of attaining the designations. I hope to provide answers to some of the questions that other faculty…

  16. Family Law and Family Studies: Professor's Views

    Science.gov (United States)

    Hicks, Mary W.; And Others

    1977-01-01

    The results of a survey of family studies faculty concerning the inclusion of family law topics in family studies courses are discussed. The professor's needs for training and resources in the area of family and the law are identified and recommendations for meeting these needs are suggested. (Author)

  17. Professor Attitudes and Beliefs about Teaching Evolution

    Science.gov (United States)

    Barnes, Maryann Elizabeth

    Teaching evolution has been shown to be a challenge for faculty, in both K-12 and postsecondary education. Many of these challenges stem from perceived conflicts not only between religion and evolution, but also faculty beliefs about religion, it's compatibility with evolutionary theory, and it's proper role in classroom curriculum. Studies suggest that if educators engage with students' religious beliefs and identity, this may help students have positive attitudes towards evolution. The aim of this study was to reveal attitudes and beliefs professors have about addressing religion and providing religious scientist role models to students when teaching evolution. 15 semi-structured interviews of tenured biology professors were conducted at a large Midwestern universiy regarding their beliefs, experiences, and strategies teaching evolution and particularly, their willingness to address religion in a class section on evolution. Following a qualitative analysis of transcripts, professors did not agree on whether or not it is their job to help students accept evolution (although the majority said it is not), nor did they agree on a definition of "acceptance of evolution". Professors are willing to engage in students' religious beliefs, if this would help their students accept evolution. Finally, professors perceived many challenges to engaging students' religious beliefs in a science classroom such as the appropriateness of the material for a science class, large class sizes, and time constraints. Given the results of this study, the author concludes that instructors must come to a consensus about their goals as biology educators as well as what "acceptance of evolution" means, before they can realistically apply the engagement of student's religious beliefs and identity as an educational strategy.

  18. A response to Fu et al.'s "Educational interventions to increase HPV vaccination acceptance".

    Science.gov (United States)

    Shapiro, Gilla K; Joyal-Desmarais, Keven; Perez, Samara; Rosberger, Zeev

    2014-11-12

    This commentary is a response to a systematic review, recently published in Vaccine, which investigates the effectiveness of educational interventions in increasing uptake of the human papillomavirus vaccine. The systematic review by Fu et al. (2014) enhances the field's understanding of human papillomavirus vaccine interventions; however, their review contains a number of conceptual and methodological limitations. This commentary begins by addressing these limitations. We then address the importance of studying human papillomavirus vaccine interventions in diverse populations, and conclude by making recommendations for future research.

  19. Interferometric view of the circumstellar envelopes of northern FU Orionis-type stars

    Science.gov (United States)

    Fehér, O.; Kóspál, Á.; Ábrahám, P.; Hogerheijde, M. R.; Brinch, C.

    2017-11-01

    Context. FU Orionis-type objects are pre-main sequence, low-mass stars with large outbursts in visible light that last for several years or decades. They are thought to represent an evolutionary phase during the life of every young star when accretion from the circumstellar disk is enhanced during recurring time periods. These outbursts are able to rapidly build up the star while affecting the physical conditions inside the circumstellar disk and thus the ongoing or future planet formation. In many models, infall from a circumstellar envelope seems to be necessary to trigger the outbursts. Aims: We characterise the morphology and the physical parameters of the circumstellar material around FU Orionis-type stars using the emission of millimetre-wavelength molecular tracers. The high-spatial-resolution study provides insight into the evolutionary state of the objects, the distribution of parameters in the envelopes and the physical processes forming the environment of these stars. Methods: We observed the J = 1-0 rotational transition of 13CO and C18O towards eight northern FU Orionis-type stars (V1057 Cyg, V1515 Cyg, V2492 Cyg, V2493 Cyg, V1735 Cyg, V733 Cep, RNO 1B and RNO 1C) and determine the spatial and velocity structure of the circumstellar gas on a scale of a few thousand AU. We derive temperatures and envelope masses and discuss the kinematics of the circumstellar material. Results: We detected extended CO emission associated with all our targets. Smaller-scale CO clumps were found to be associated with five objects with radii of 2000-5000 AU and masses of 0.02-0.5 M⊙; these are clearly heated by the central stars. Three of these envelopes are also strongly detected in the 2.7 mm continuum. No central CO clumps were detected around V733 Cep and V710 Cas which can be interpreted as envelopes but there are many other clumps in their environments. Traces of outflow activity were observed towards V1735 Cyg, V733 Cep and V710 Cas. Conclusions: The diversity of

  20. Photometric Study of the FU Orionis Object BBW 76 from the Bamberg Observatory Southern Sky Survey

    Science.gov (United States)

    Borisova, A.; Tsvetkova, K. P.; Tsvetkov, M. K.

    2006-04-01

    The Bamberg Observatory Southern Sky Survey provided 93 photographic plates with the FU Orionis object BBW 76, clearly detectable in the time interval 1963-1976. We perform aperture photometry of BBW 76 from the 2 x 2 degrees area near target star scanned with the Epson Expression 1640 XL flatbed scanner. For each plate a transformation of plate magnitude to the GSC 2.2 magnitudes in B photographic band was found out for selected reference stars, and used for deriving B magnitudes of BBW 76. The analysis of the photometric behaviour of BBW 76 is presented.

  1. Der ökologische Fußabdruck: biologische Mutterkuh- und konventionelle Mastrinderhaltung im Vergleich

    OpenAIRE

    Kratochvil, Dr. Ruth; Dekker, Sanne

    2004-01-01

    Der ökologische Fußabdruck ist ein Werkzeug, um den anthropogenen Naturverbrauch vor dem Hintergrund einer nachhaltigen Entwicklung zu bilanzieren. Im vorliegenden Artikel wurde der ÖFA für Rindfleisch aus ökologischer Mutterkuh- und konventioneller Mastrinderhaltung berechnet. Bedingt durch extensive Grünlandbewirtschaftung, höheren Stallgebäude- und Strohbedarf sowie niedrigere tierische Leistungen ist der ÖFA für Rindfleisch aus Mutterkuhhaltung fünf Mal so hoch wie jener für Rindfleisch a...

  2. Yuriko and Michael Renardy reappointed Class of 1950 Professors

    OpenAIRE

    Owczarski, Mark

    2010-01-01

    Yuriko and Michael Renardy, professors of mathematics in the College of Science at Virginia Tech, have been reappointed as the Virginia Tech Class of 1950 Professors by the Virginia Tech Board of Visitors.

  3. Self-Assembling Monomeric Nucleoside Molecular Nanoparticles Loaded with 5-FU Enhancing Therapeutic Efficacy against Oral Cancer.

    Science.gov (United States)

    Zhao, Hang; Feng, Hui; Liu, Dongjuan; Liu, Jiang; Ji, Ning; Chen, Fangman; Luo, Xiaobo; Zhou, Yu; Dan, Hongxia; Zeng, Xin; Li, Jing; Sun, Congkui; Meng, Jinyu; Ju, Xiaojie; Zhou, Min; Yang, Hanshuo; Li, Longjiang; Liang, Xinhua; Chu, Liangyin; Jiang, Lu; He, Yang; Chen, Qianming

    2015-10-27

    Conventional oligonucleotide based drug delivery systems suffer from lengthy synthetic protocols, high cost, and poor chemical or enzymatic stability under certain circumstances. Canonical free individual nucleosides cannot form stable nanostructures in aqueous solution as drug vehicles. Here, we report the development of a monomeric self-assembled nucleoside nanoparticle (SNNP) into an efficient drug delivery system which has currently no parallel in such field. This was achieved using a l-configurational pyrimido[4,5-d]pyrimidine nucleoside building block that can form robust discrete nanoparticles in just one step with water as the sole solvent. Its high biocompatibility and low toxicity was demonstrated in vitro and in vivo. In mouse xenograft model of oral squamous cell carcinoma (OSCC), SNNP loaded with 5-fluoro-uracile (5-FU-SNNP) remarkably retarded the tumor growth compared with free 5-FU, albeit SNNP alone showed no antitumor effect. The stability in blood circulation and the effective concentration of 5-FU in tumor tissue were increased upon the loading with SNNP. TUNEL and immunohistochemistry analyses further indicated that the superior in vivo antitumor efficacy of 5-FU-SNNP compared to free 5-FU was associated with an enhanced degree of inhibition of cell proliferation and stimulation of cell apoptosis. Furthermore, SNNP alleviated the toxic side effects of 5-FU. These findings suggested that when loaded with SNNP, 5-FU has better antitumor efficacy and lower side effects, indicating that SNNP can efficiently act as a readily accessible, robust, biocompatible and low-toxic nanobiomaterial which may find wide therapeutic applications clinically in the future.

  4. 陆克文:"中国通"成为澳大利亚工党新船长%Kevin Rudd: "a sinologist" becoming new leader of the ALP

    Institute of Scientific and Technical Information of China (English)

    海之灵

    2007-01-01

    @@ 2006年12月4日,澳大利亚最大政党、主要反对党工党举行领袖选举,现年50岁的原影子内阁外交贸易部长陆克文(Kevin Rudd)以49票对39票击败原领袖比兹利当选领袖.此前因备战下届大选而愈演愈烈的工党领导权之争终于划上句号.澳社会普遍认为,陆克文的当选意味着工党一个新时代的开始.

  5. Categorization of Quantum Mechanics Problems by Professors and Students

    Science.gov (United States)

    Lin, Shih-Yin; Singh, Chandralekha

    2010-01-01

    We discuss the categorization of 20 quantum mechanics problems by physics professors and undergraduate students from two honours-level quantum mechanics courses. Professors and students were asked to categorize the problems based upon similarity of solution. We also had individual discussions with professors who categorized the problems. Faculty…

  6. E-Mail from Professor Enhances Student Motivation and Attitudes

    Science.gov (United States)

    Legg, Angela M.; Wilson, Janie H.

    2009-01-01

    Traditionally, professors use the first day of class to build rapport. However, current technology allows professors to contact students prior to the first day of class. This study assessed how the receipt of a welcoming e-mail from a female professor 1 week before the first day of class affected student motivation and attitudes toward the…

  7. Connect and Thrive: Perspectives from a Newly Tenured Professor

    Science.gov (United States)

    Ciocchetti, Corey A.

    2011-01-01

    This essay encapsulates the author's perspective on how average professors can become highly effective professors. The author asserts that the secret rests in the ability to genuinely connect with students. Connecting really matters--even if it takes some personality adaptation and thrusts academics out of their comfort zones. Many professors fail…

  8. Anti-Fat Bias by Professors Teaching Physical Education Majors

    Science.gov (United States)

    Fontana, Fabio; Furtado, Ovande, Jr.; Mazzardo, Oldemar, Jr.; Hong, Deockki; de Campos, Wagner

    2017-01-01

    Anti-fat bias by professors in physical education departments may interfere with the training provided to pre-service teachers. The purpose of this study was to evaluate the attitudes of professors in physical education departments toward obese individuals. Professors from randomly selected institutions across all four US regions participated in…

  9. 26 CFR 509.115 - Visiting professors or teachers.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 19 2010-04-01 2010-04-01 false Visiting professors or teachers. 509.115...) REGULATIONS UNDER TAX CONVENTIONS SWITZERLAND General Income Tax § 509.115 Visiting professors or teachers. (a) General. Pursuant to Article XII of the convention, a professor or teacher, a nonresident alien who is a...

  10. Variables That Can Affect Student Ratings of Their Professors

    Science.gov (United States)

    Gotlieb, Jerry

    2013-01-01

    Attribution theory was applied to help predict the results of an experiment that examined the effects of three independent variables on students' ratings of their professors. The dependent variables were students' perceptions of whether the professor caused the students' grades and student satisfaction with their professor. The results suggest…

  11. Gossypol sensitizes the antitumor activity of 5-FU through down-regulation of thymidylate synthase in human colon carcinoma cells.

    Science.gov (United States)

    Yang, Dan; Qu, Jinglei; Qu, Xiujuan; Cao, Yubo; Xu, Ling; Hou, Kezuo; Feng, Wanyu; Liu, Yunpeng

    2015-09-01

    5-Fluorouracil (5-FU) is the basic chemotherapeutic agent used to treat colon cancer. However, the sensitivity of colon cancer cells to 5-FU is limited. Gossypol is a polyphenolic extract of cottonseeds. The purpose of this study was to investigate the activities and related mechanism of gossypol alone or in combination with 5-FU against human colon carcinoma cells. The IC50 of gossypol or/and 5-FU in vitro was tested by 3-(4,5-dimethyl thiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay, and the drug interaction was analyzed using the CalcuSyn method. Cell apoptosis was determined using presidium iodide staining and flow cytometric analysis. Western blotting was used to determine the expression of proteins. Transient transfection method was used to silence protein. The IC₅₀ at 48 h of gossypol in colon cancer cells was 26.11 ± 1.04 μmol/L in HT-29 cells, 14.11 ± 1.08 μmol/L in HCT116 cells, and 21.83 ± 1.05 μmol/L in RKO cells. When gossypol was combined with 5-FU, a synergistic cytotoxic effect was observed in HT-29 cells, HCT116 cells, and RKO cells compared with treatment with gossypol or 5-FU alone. The Western blotting results indicated that gossypol down-regulated thymidylate synthase (TS) rather than thymidine phosphorylase protein expression. Furthermore, the mTOR/p70S6K1 signaling pathway was inhibited in gossypol-treated colon cancer cells, and consequently, cyclin D1 expression was decreased, suggesting an additional mechanism of the observed antiproliferative synergistic interactions. All the observation was confirmed by silencing TS and inactivating the mTOR/p70S6K1 signaling pathway by rapamycin, both of which increased the chemo-sensitizing efficacy of 5-FU. These findings suggest that gossypol-mediated down-regulation of TS, cyclin D1, and the mTOR/p70S6K1 signaling pathways enhances the anti-tumor effect of 5-FU. Ultimately, our data exposed a new action for gossypol as an enhancer of 5-FU-induced cell growth suppression.

  12. Dosimetric study of photobiomodulation therapy in 5-FU-induced oral mucositis in hamsters

    Science.gov (United States)

    Cotomacio, Claudia Carrara; Campos, Luana; Nesadal de Souza, Douglas; Arana-Chavez, Victor Elias; Simões, Alyne

    2017-01-01

    Oral mucositis (OM) is a debilitating consequence of cancer treatment that could be treated with photobiomodulation therapy (PBMT); however, there is no consensus about its dosimetric parameters for OM healing. The aim of this study was to compare different PBMT protocols on OM treatment, through clinical and histological analysis. Thirty hamsters were used, in an induced model of OM by 5-fluorouracil (5-FU) and superficial scratching, in seven days of follow-up. The animals were divided into five groups: control (C), which received only anesthesia and chemotherapeutic vehicle; chemotherapy (Ch), which received anesthesia, 5-FU, and scratches; laser 1 (L1), the same as Ch group, PBMT 6 J/cm2 and 0.24 J (one point); laser 2 (L2), the same as Ch group, PBMT 25 J/cm2 and 1 J (one point); and laser 3 (L3), the same as Ch group, PBMT 4 points of 0.24 J and 6 J/cm2 each. The laser used has λ=660 nm, 0.04 cm2 of spot area, and 40 mW. The best PBMT protocol to maintain lowest OM levels compared to Ch group was L1, followed by L2 and L3. Our results suggest that the application mode of PBMT and the energy delivered per area could interfere with the OM healing.

  13. The effects of lyophilization on the stability of liposomes containing 5-FU.

    Science.gov (United States)

    Glavas-Dodov, M; Fredro-Kumbaradzi, E; Goracinova, K; Simonoska, M; Calis, S; Trajkovic-Jolevska, S; Hincal, A A

    2005-03-03

    Multilamellar liposomes containing 5-fluorouracil (5-FU) were prepared by modified lipid film hydration method and were lyophilized with or without saccharose as cryoprotectant. The effect of lyophilization on the stability of liposomes was evaluated by comparing the vesicle size, encapsulation efficiency and the drug release rate before and after lyophilization/rehydration. The process of lyophilization, without cryoprotectant, resulted in particle size increase and significant content leakage. By the addition of saccharose, the lipid bilayers become more stable and less permeable to the encapsulated drug, saccharose imparted 5-FU retention of about 80% after lyophilization/rehydration. Freeze-drying did not affect the particle size of liposomes containing saccharose as cryoprotectant. The drug release profiles of rehydrated liposomes followed Higuchi's square root model. Also, the obtained release profiles were all biphasic: a rapid initial drug release phase (burst release of the portion of the drug that leaked out of liposomes during the lyophilization) was followed by a slower, approximately constant drug release phase (zero-order kinetics).

  14. Chemoradiotherapy with low-dose cisplatin and 5-FU for advanced esophageal cancer

    Energy Technology Data Exchange (ETDEWEB)

    Tajima, Masayuki; Ichikawa, Wataru; Takagi, Youko; Uetake, Yasuhiro; Kojima, Kazuyuki; Osanai, Takayuki; Takenaka, Satoru; Nihei, Zenro; Sugihara, Kenichi [Tokyo Medical and Dental Univ. (Japan). School of Medicine

    2000-10-01

    We evaluated the efficacy of chemoradiotherapy (CRT) for advanced esophageal cancer, from the view point of response. The relationship between chemoradiosensitivity and dihydropyrimidine dehydrogenase (DPD), thymidylate synthase (TS), and p53 was investigated immunohistochemically. Thirteen patients with inoperable advanced esophageal cancer were involved in this study. CDDP of 10 mg/m{sup 2}/day and 5-FU of 335 mg/m{sup 2}/day were infused intravenously (day 1-5, day 15-19). Radiation was delivered concomitantly at a total dose of 30 Gy. Expressions of p53, DPD and TS were detected using immunohistology in the biopsy samples taken before CRT from 8 patients. Partial response was observed in 8 cases, no change in 4 cases, and progressive disease in one case. The overall response rate was 62%. The reduction rate was higher in tumors positive for p53 expression than in negative ones. The same was true for DPD and TS. The treatment effect was more precisely predicted by combination of p53, DPD and TS. CRT with low-dose CDDP + 5-FU chemotherapy was effective and combination with p53, DPD and TS might be a predictive marker for CRT in patients with advanced esophageal cancer. (author)

  15. Anticancer effect of bromelain with and without cisplatin or 5-FU on malignant peritoneal mesothelioma cells.

    Science.gov (United States)

    Pillai, Krishna; Ehteda, Anahid; Akhter, Javid; Chua, Terence C; Morris, David L

    2014-02-01

    Malignant peritoneal mesothelioma (MPM) is a rare neoplasm of the peritoneum, causally related to asbestos exposure. Nonspecific symptoms with a late diagnosis results in poor survival (Bromelain (cysteine proteinase) hydrolyses glycosidic bonds. Therefore, we investigated the antitumour effect of bromelain on MUC1-expressing MPM cell lines. MUC1 expressions in cells were assessed using immunofluorescent probes with cells grown on cover slips and western blot analysis on cell lysates. The cell lines were treated with various concentrations of bromelain and after 4 and 72 h, their viability was assessed using standard sulforhodamine assays. The cells were also treated with combinations of bromelain and cytotoxic drugs (cisplatin or 5-FU) and their viability was assessed at 72 h. Finally, with western blotting, the effects of bromelain on cellular survival proteins were investigated. PET cells expressed more MUC1 compared with YOU cells. The cell viability of both PET and YOU cells was adversely affected by bromelain, with PET cells being slightly resistant. The addition of bromelain increased the cytotoxicity of cisplatin significantly in both cell lines. However, 5-FU with bromelain did not show any significant increase in cytotoxicity. Bromelain-induced cell death is by apoptosis and autophagy. Bromelain has the potential of being developed as a therapeutic agent in MPM.

  16. Study of the Outflow and Disk surrounding a Post-Outburst FU-Orionis Star

    Science.gov (United States)

    Mellon, Samuel N.; Perez, L. M.

    2014-01-01

    PP 13 is a fan-shaped cometary nebula located in the constellation of Perseus and embedded in the L1473 dark cloud. At optical wavelengths this region is obscured by the surrounding dark cloud, while at infrared and longer wavelengths two northern objects (PP13Na & PP13Nb) and one southern object (PP13S) are revealed. In the past, the young stellar object inside PP13S, called PP13S*, experienced an FU-Orionis type outburst due to a massive accretion episode and is currently returning to its quiescent state. Studying the FU-Orionis phase is crucial to our understanding of how low mass stars form; it is theorized that all low-mass stars go through this outburst phase while they are forming. I used CARMA 3mm interferometric observations of the PP13 region to study the continuum and molecular line emissions from PP13. With these observations, I determined the source of the previously detected outflow and learned new information about the double star system PP13Na and PP13Nb. Although I was not able to detect the accretion disk in the gas emissions, I plan to use computer modeling to help provide constraints on the properties of PP13S* and its outflow.

  17. [Clinical effects of Fu Fang Ya Tong Ding on gingivitis and pericoronitis].

    Science.gov (United States)

    Wan, Hu-Chun; Zhang, Shuang; Wu, Ni-Ya; Kang, Dong; Hu, Li-Jie; Wang, Li-Zhi; Zhang, Ji-Ying; Xie, Ping

    2008-04-01

    To evaluate the clinical effects of Fu Fang Ya Tong Ding on treatment of gingivitis and pericoronitis. 120 clinical patients with gingivitis or pericoronitis were randomly divided into 3 groups (40 patients in each group). After routine rinse treatment for all patients, patients in the test group were treated with Fu Fang Ya Tong Ding, patients in the positive group were treated with iodine glycerol, while that time patients in the negative group received no treatment anymore. Ten minutes after treatment, visual analogue scale (VAS) was used to record the severity of pain for each patient. 3 days and 7 days later, pain and inflammation degree were also recorded by pain three-degree scoring method and index of gingivitis. The total treatment effects were evaluated under a comprehensive clinical treatment standard. 10 minutes after treatment, 40.0% of patients in the test group had almost no pain, while no obvious reduction of pain was found in the control group. 3 days, 7 days after the treatment, 92.5%, 95.0% of patients in the test group had no pain, and 55.0%, 90.0% of patients in the positive group had no pain. In the negative group, there were 47.5% of patients which pain was still remained in 7 days. 7 days after treatment, gingival index in the test group reduced by 25.0% and 42.8% compared with the positive and negative groups (Ppericoronitis through significantly reducing inflammation and pain.

  18. Translasi Pencak Silat Kedalam Film Animasi (Studi Kasus Film Kung Fu Panda

    Directory of Open Access Journals (Sweden)

    Riyo Ramadhan

    2017-09-01

    Full Text Available Sebagai tradisi yang telah membudaya dari sejak zaman dahulu kala, pencak silat lahir sebagai benteng kekuatan pertahanan diri sekaligus menjadi seni yang memperkaya khazanah kebudayaan bangsa Indonesia. Namun, kuatnya terpaan kebudayaan seni bela diri impor yang masuk (karate, kung fu, tae kwon do, muay thai, capoeira, dll, yang selalu didukung dengan berbagai kemasan media entertainment modern, membuat silat menjadi kalah populer bahkan di mata dan persepsi masyarakat Indonesia sendiri. Hal ini mengakibatkan para generasi muda memandang seni bela diri impor menjadi lebih superior ketimbang pencak silat. Jika hal ini terus berlangsung tanpa ada usaha untuk mengembangkan pencak silat melalui media modern, maka akan sangat sulit untuk mempertahankan dan mengembangkan tradisi ini di masa depan. Tujuan dari makalah ini ialah untuk membuktikan dan menggali potensi animasi sebagai media alternatif yang efektif untuk memvisualisasikan adegan dan cerita bertemakan pencak silat. Adapun studi kasus yang menjadi acuan dalam penelitian ialah film animasi “Kung Fu Panda”. Penelitian ini mengkaji studi kasus dengan menggunakan metode kualitatif deskriptif, lalu dianalisis dengan pendekatan analisis deskriptif untuk mengkaji dan mengidentifikasi pemasalahan dan solusi. Pembahasan dari makalah lebih ditekankan pada kekuatan penyampaikan cerita melalui gambar (visual storytelling yang efektif terkait dengan pencak silat. Hasil dari penelitian ialah cara penyampaian pesan yang efektif mengenai elemen dan esensi pencak silat sebagai bentuk translasinya kedalam film animasi. Pesan tersebut dapat disampaikan dengan menggunakan aspek narasi, gesture, dan simbol yang diakomodasi dengan aspek visual storytelling. Translating Pencak Silat Into An Animation Film (Case Study The Film Kung Fu Panda Abstract. A tradition that has been part of Indonesian culture since ancient times, pencak silat was born as a form of self-defense and at the same time has grown into an

  19. Spotlight on CERN : Professor Michel Spiro

    CERN Multimedia

    CERN video productions

    2011-01-01

    20 Member states throughout Europe. A geographical expansion underway. A worldwide, international collaboration and a scientific challenge on a scale second to none. In view of this complexity, how is CERN managed? This is the remit of the CERN council, which notably defines the strategic programmes, annual objectives, approves the annual budget and nominates the directorate. I am pleased to welcome Professor Michel Spiro, scientific director of the CNRS in France and CERN Council presdient since 2010. On today’s agenda: Expansion, innovation and communication. Hello and welcome Professor.. François et Stéphan are of course with me today to discuss such matters as antimatter, press and we will also be talking water and towers… I will say no more. It’s good to see you both ! And welcome to you all for this latest edition of Spotlight on CERN.

  20. 31 July 2014 - Professor M. Kastner

    CERN Multimedia

    Egli, Laurent

    2014-01-01

    MIT Faculty Member Donner Professor of Physics Massachusetts Institute of Technology United States of America, Prof. M. Kastner visiting the LHC tunnel at Point 5 with Beams Department M. Solfaroli Camillocci, LHC superconducting magnet assembly hall visit with L. Rossi and R. Principe, LHC Computing Grid Project presentation and computer centre visit with I. Bird and signing the guest book with CERN Director-General R. Heuer.

  1. [Homage to Professor Dr. Nicasio Etchepareborda].

    Science.gov (United States)

    1998-11-01

    During a solemn academic act, de Main Classroom of the Facultad de Odontologia de Buenos Aires was named after Prof. Dr. Nicasio Etchepareborda. He has been the first professor at the Escuela de Odontologia and its organizer, after having obtained his Dentistry degree at the Dental School of Paris, in 1882. The new school was founded in 1891, and its activities began the following year.

  2. In memory of Professor Paolo Talamucci

    Directory of Open Access Journals (Sweden)

    Cantiani M

    2010-05-01

    Full Text Available Paolo Talamucci, Full Professor of Range Management at the Università degli Studi in Florence from 1975 to 2001, passed away on 27th November 2009, after a brief and unrelenting illness. Professor Talamucci spent many long years in the field of research, in both Mediterranean and Alpine regions. His research, profoundly rooted in the territory he was studying, holistic in its approach and rigorously scientific, was characterized by a strong interdisciplinary element, seeking always to take into account the totality of the components of the ecosystem. Professor Talamucci was one of the first scholars of the pastoral system to highlight the problems related to the abandonment of traditional animal husbandry in mountainous zones and to look for ways to counteract the undesirable transformation of the landscape and the consequent loss of biodiversity. His curriculum and his numerous scientific publications bear testimony not only to the prestigious research institutes, world-wide, with which he was associated, but also to the important international dimension of his research.

  3. APOSENTADORIA: como professores vivenciam este momento?

    Directory of Open Access Journals (Sweden)

    Cristiane Nervis Conrado Machado

    2017-05-01

    Full Text Available O presente artigo buscou compreender as implicações que a aposentadoria causa na vida de professores, levando em conta o significado que a aposentadoria representa à estes, considerando os pontos de maior mudança após a aposentadoria, bem como os aspectos positivos e negativos causados pela aposentadoria na percepção dos sujeitos da pesquisa. Para tanto, foi realizada uma pesquisa qualitativa caracterizada como exploratória e descritiva com professores aposentados por mais de dois anos, com idade entre 58 e 66 anos, através de entrevistas individuais, com roteiros semiestruturados. A análise dos dados foi por meio da análise de conteúdo de Bardin (2011. Entre os principais resultados, destaca-se o significado de “liberdade” que a aposentadoria representa, a rotina como maior mudança e flexibilidade de horários dentre os pontos positivos e a falta dos alunos como aspecto negativo, contudo, pode-se perceber que a aposentadoria possibilitou e contribuiu para que os professores pudessem desfrutar de momentos de lazer, dedicando cuidado à família e realizando seus anseios e vontades.

  4. [Preparation of ethosomes encapsulated with 5-fluorouracil and the effect of local administered 5-FU ethosome on laryngotracheal stenosis of rabbit].

    Science.gov (United States)

    Yang, Xizhi; Ao, Huafei; Cheng, Xuefeng; Gu, Jian; Kong, Deqiu; Mao, Xiaohui

    2012-10-01

    To evaluate the efficacy of Ethosomes encapsulated with 5-FU in treatment of laryngotracheal stenosis in rabbit models. The 5-FU ethosome was prepared by the thin film hydration method, and the size distribution and the encapsulation efficiency was investigated. The tracheal mucosa was scraped about 0.5 cm in width with a nylon brush to induce the scar formation in the airway,then animals were divided into three groups: 5-FU ethosome group,5-FU group and saline group. Drugs were injected into scar by paracentesis under endoscope in each group respectively. The severity of stenosis was observed under laryngofiberoscope immediately, 7, 14, 21 days after administration. Airway stenosis of 5-FU ethosome group was not significantly different compared with 5-FU group at 7 days after administration, but 5-FU ethosome significantly reduced the airway stenosis at 21 days after administration when compared with 5-FU group and no restenosis was noticed during the observation period. Ethosomes encapsulated with 5-FU was effective for laryngotracheal stenosis. It is a potentially new method for ameliorating airway stenosis originated from granulation tissue.

  5. [Application of ″Fu Yang and activating blood circulation″ in treatment of unstable angina pectoris patients].

    Science.gov (United States)

    Gao, Jia-Liang; Li, Jun; Wang, Jie

    2016-02-01

    Coronary heart disease(CHD) has become a major public health problem in the world, while the unstable angina (UA) is one of an important type. Hypofunction of yang qi in chest and cardiac blood stasis has been considered as the basic pathogenesis of UA.According to the deficiency of yang and blood stasis run through the process of CHD, fu yang and activating blood circulation could be main treatment. Wenxin decoction which has the function of fu yang and activating blood circulation, not only can effectively improve the symptoms of angina pectoris, the ischemic ECG, but also can significantly improve blood rheology, blood lipids and so on. So deepening the theory of ″fu yang and activating blood circulation″ and the application of ″Wenxin decoction″ in the treatment of UA would have an important clinical value for improving the therapeutic efficacy of CHD. Copyright© by the Chinese Pharmaceutical Association.

  6. Chemoresistance to 5-FU inhibited by 635 nm LED irradiation in CD133+ KB cell line.

    Science.gov (United States)

    Kim, Donghwi; Park, Mineon; Jang, Hyunwoong; Hyun, Hoon; Lim, Wonbong

    2018-01-01

    Consistent with cancer stem cell theory, a small fraction of cancer cells, described as cancer stem cells (CSCs), may promote tumor recurrence and anti-cancer drug resistance. Therefore, much effort has been devoted to the development of CSC targeted therapy to vanquish drug resistance. In this study, we have investigated the effect of multiple light-emitting diode (LED) irradiation treatments with conventional anti-cancer drugs on CSC-like oral cancer cells that acquired stemness by ectopic over expression of CD133. To evaluate combined LED irradiation anti-cancer drug effects, we investigated the chemosensitizing effect of 635 nm irradiation on 5-fluorouracil (5FU)-treated KBCD133+ and KBVec cells, interrogating the underlying molecular mechanisms associated with stemness and apoptosis that are responsible for chemopreventive activity. In addition, combination therapy with LED irradiation and 5-FU treatment was carried out in KBCD133+ and KBVec cell-inoculated mouse models. LED irradiation of 635 nm inhibited CSC-like properties consistent with a decrease in OCT4 and NANOG protein expression, reducing colony-forming ability. In addition, LED irradiation enhanced 5-FU-induced cytotoxicity and improved 5-FU chemosensitivity in KBCD133+ via enhancement of apoptosis. These findings were validated in vivo, wherein LED irradiation combined with 5-FU treatment inhibited tumor growth in KBCD133+-inoculated mice. Collectively, our results provide novel evidence for 635 nm irradiation-induced 5-FU chemosensitization of CSC in oral cancer. In addition, this research highlights that 635 nm LED irradiation may serve as an adjunct treatment to conventional chemotherapeutic drugs in patients with oral cancer.

  7. Visit of Professor Shigehiko Hasumi. President of Tokyo University, Japan, Professor Kazuo Okamoto, Head of Graduate School of Mathematical Sciences, Professor Toshiteru Matsuura, Head of Graduate School of Arts and Sciences

    CERN Multimedia

    Patrice Loiez

    1999-01-01

    Visit of Professor Shigehiko Hasumi. President of Tokyo University, Japan, Professor Kazuo Okamoto, Head of Graduate School of Mathematical Sciences, Professor Toshiteru Matsuura, Head of Graduate School of Arts and Sciences

  8. TrAnsFuSE refines the search for protein function: oxidoreductases.

    Science.gov (United States)

    Harel, Arye; Falkowski, Paul; Bromberg, Yana

    2012-07-01

    Non-equilibrium catalysis of electron transfer reactions (i.e. redox) regulates the flux of key elements found in biological macromolecules. The enzymes responsible, oxidoreductases, contain specific transition metals in poorly sequence-conserved domains. These domains evolved ∼2.4 billion years ago in microbes and spread across the tree of life. We lack understanding of how oxidoreductases evolved; divergence of sequences makes identification difficult. We developed a method to recognise the various versions of these enzyme-domains in unannotated sequence-space. Often, homology is used to transfer function annotations from experimentally resolved domains to unannotated sequences. Unreliability of inferring homology below 30% sequence identity limits single-sequence based searches. Misaligned functional sites may compromise annotation transfer from even very similar sequences. Combining profile-based searches with knowledge of functional sites could improve domain detection accuracy. Here we present an approach that enhances the search for redox domains using catalytic site annotations. From the scientific literature, we validated annotations of 104 InterPro domains indicated as using "transition metals in redox reactions." These domains mediate electron transfer in 20% of oxidoreductases, primarily employing iron, copper and molybdenum. We used the experimentally identified catalytic residues in these domains to validate sequence alignment-based protein function annotations. Our method, TrAnsFuSE, is 11% and 14% more accurate than PSI-BLAST and InterPro, respectively. Moreover, it is robust for use with other functional residues-we attain higher accuracy at comparable coverage using metal binding, in addition to catalytic, sites. TrAnsFuSE can be used to focus the study of the vast amounts of unannotated sequencing data from meta-/genome projects.

  9. [Post-stroke constipation treated with acupuncture therapy of regulating qi circulation of fu-organ].

    Science.gov (United States)

    Ren, Zhen; Wu, Qing-Ming; Li, Dan-Dan; Liu, Wei-Ai; Li, Xiang-Rong; Lin, Xu-Ming

    2013-10-01

    To compare the difference in the efficacy on post-stroke constipation between acupuncture therapy of regulating qi circulation of fe-organ and Shengxue Tongbian Capsules. Seventy-five patients of post-stroke constipation were randomized into an acupuncture group (39 cases) and a Chinese medicine group (36 cases). The unit mode comprehensive therapy of stroke was adopted as basic treatment in the two groups. In the acupuncture group, acupuncture therapy of regulating qi circulation of fu-organ was added at Tianshu (ST 25), Zhigou (TE 6), Qihai (CV 6) and Zusanli (ST 36), once every day. In the Chinese medicine group, Shengrue Tongbian Capsules were supplemented for oral administration, once every day, 10 g each time. The clinical symptom score of constipation was observed before treatment, after 1 and 2 weeks treatment in the two groups, respectively. The efficacy in 1 week and 2 weeks of treatment and the adverse reaction were observed. In 1 and 2 weeks of treatment, the clinical symptom score of constipation was reduced significantly as compared with that before treatment in the two groups (all P acupuncture group were significant than those in the Chinese medicine group in 2 weeks of treatment (8.03 +/- 2.38 vs 9.20 +/- 2.45, P acupuncture group; and there were 1 case of abdominal pain, 3 cases of diarrhea and 2 cases of nausea and vomiting in the Chinese medicine group. Both the acupuncture therapy of regulating qi circulation of fu-organ and Shengxue Tongbian Capsules achieve the significant efficacy on post-stroke constipation. The efficacy of the acupuncture therapy of regulating qi circulation of fe-organ is better and the adverse reaction is less after long-term persistent treatment.

  10. Religiosidade em alunos e professores portugueses

    OpenAIRE

    Ferreira, Ana Maria Mendes dos Santos Veríssimo

    2005-01-01

    Tese de Doutoramento em Ciências da Educação na especialidade de Educação Intercultural apresentada à Universidade Aberta Esta tese pretende analisar a religiosidade em alunos e professores, sendo a religiosidade entendida como o grau de ligação ou aceitação que cada indivíduo tem face à instituição religiosa (Alston, 1875) e à forma como põe em prática as crenças e os rituais (Shafranske e Malony, 1990). Para medir a religiosidade foram utilizados diversos instrumentos – a escala de Atitu...

  11. Professor Stewart's hoard of mathematical treasures

    CERN Document Server

    Stewart, Ian

    2010-01-01

    Ian Stewart, author of the bestselling Professor Stewart's Cabinet of Mathematical Curiosities, presents a new and magical mix of games, puzzles, paradoxes, brainteasers, and riddles. He mingles these with forays into ancient and modern mathematical thought, appallingly hilarious mathematical jokes, and enquiries into the great mathematical challenges of the present and past. Amongst a host of arcane and astonishing facts about every kind of number from irrational or imaginary to complex or cuneiform, we find out: how to organise chaos; how matter balances anti-matter; how to turn a sphere i

  12. Boodskap van Professor Dr. J. Waterink

    Directory of Open Access Journals (Sweden)

    J. Waterink

    1955-03-01

    Full Text Available Boodskap van Professor Dr. J. Waterinkter gelegendheid van die verlening aan hem van de graad Doctor Educationis, honoris causa, door de Universiteit voor Christelijk Hoger Onderwijs te Potchefstroom op Zaterdag, 26 Maart 1955, en op die dag voorgelezen door de heer Jan van den Berg, Buitengewoon en Gevolmachtigd Ambassadeur van Hare Mi iesteit de Koningin der Nederlanden. Mijnheer, de Kanselier, Mijnheer de Voorzitter van de Raad, Mijnheer deVice-Kanselier en Rector, overige Heren ambtsdragers, en gij alien,die herwaarts kwaanit ter gelegenheid van deze Gradendag,zeer geachte en zeer gewenste toehoorders.

  13. Fuels planning: science synthesis and integration; environmental consequences fact sheet 12: Water Erosion Prediction Project (WEPP) Fuel Management (FuMe) tool

    Science.gov (United States)

    William Elliot; David Hall

    2005-01-01

    The Water Erosion Prediction Project (WEPP) Fuel Management (FuMe) tool was developed to estimate sediment generated by fuel management activities. WEPP FuMe estimates sediment generated for 12 fuel-related conditions from a single input. This fact sheet identifies the intended users and uses, required inputs, what the model does, and tells the user how to obtain the...

  14. The Effect of 5 FU on the Expression of Transforming Growth Factor Beta-1 (Tgf-1 in Cultured Tendon Cells

    Directory of Open Access Journals (Sweden)

    Zeynep Karacor Altuntas

    2014-10-01

    Full Text Available This study investigated the effect of the treatment with 1 min exposures to 5-fluorouracil (5-FU  on the expression of TGF-beta 1 in cultured tendon cells. Fibroblasts cultured from the flexor tendons of dog paws were treated with 3 different doses of 5-FU ( control, 5-15-25 mgr /ml for 1 minute.  After 5-FU exposure  the expression of TGF –beta 1 were tested by real time Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR at 3rd and 7th days. There were no statistically significant differences in the expression levels of the TGF-b1 gene between the control group and all other groups on day 3 and 7 (p>0.05.However, when the percentage changes in the TGF-BETA1 gene expression on days 3–7 were compared, there were statistically significant differences and this was maximally observed with 89% +12 (p<0.05 in the group treated with 25-mg/ml 5-FU.  We conclude that 1min. 5-FU application may be  sufficient to prevent adhesions in tendon healing by limiting the expression of TGF-BETA1. 

  15. TS Gene Polymorphisms Are Not Good Markers of Response to 5-FU Therapy in Stage III Colon Cancer Patients

    Directory of Open Access Journals (Sweden)

    A. Fariña-Sarasqueta

    2010-01-01

    Full Text Available Aim: Although the predictive and prognostic value of thymidylate synthase (TS expression and gene polymorphism in colon cancer has been widely studied, the results are inconclusive probably because of methodological differences. With this study, we aimed to elucidate the role of TS gene polymorphisms genotyping in therapy response in stage III colon carcinoma patients treated with 5-FU adjuvant chemotherapy.

  16. Deeply embedded objects and shocked molecular hydrogen : The environment of the FU Orionis stars RNO 1B/1C

    NARCIS (Netherlands)

    Quanz, S. P.; Henning, Th.; Bouwman, J.; Linz, H.; Lahuis, F.

    2007-01-01

    We present Spitzer IRAC and IRS observations of the dark cloud L1287. The mid-infrared ( MIR) IRAC images show deeply embedded infrared sources in the vicinity of the FU Orionis objects RNO 1B and RNO 1C, suggesting their association with a small young stellar cluster. We resolve for the first time

  17. HIV drug strategies in the West--and AIDS everywhere else. An interview with Kevin M. DeCock, MD, FRCP, DTM&H. Interview by Mark Mascolini.

    Science.gov (United States)

    DeCock, K M

    1997-02-01

    Dr. Kevin M. DeCock, a physician with broad experience in infectious and tropical diseases, discussed the use of anti-HIV drugs in the West and the status of AIDS in the rest of the world. Dr. DeCock explained the importance of finding the right physician to help HIV-positive individuals direct their decisions on when to start therapy, when to switch it, and when to stop therapy. Offering preventive anti-HIV therapy, similar to treating health personnel exposed to blood of an infected patient, may become a possibility. Dr. DeCock briefly discussed subtypes of the virus that exist in different populations, and physiological and transmission features of the subtypes. Problems faced in developing countries in treating and preventing HIV infections include factors arising due to poverty, lack of medical resources, and cultural factors. A series of research priorities was suggested to prevent the spread of the disease in these resource-poor countries. Other areas discussed were prevention of perinatal HIV transmission using antiretroviral therapy, the severe problem of tuberculosis in HIV infections, especially in developing countries, and the inadequate attention Westerners give to these problems.

  18. Habitus professoral na sala de aula virtual

    Directory of Open Access Journals (Sweden)

    Alexandre Marinho Pimenta

    2014-09-01

    Full Text Available Entendendo que a indiferença na ação pedagógica contribui para a reprodução das desigualdades no sistema de ensino, o presente artigo busca captar, a partir de entrevistas semiestruturadas, traços do habitus de professores supervisores de disciplinas do curso de Licenciatura em Pedagogia na modalidade a distância na Universidade de Brasília - UnB no âmbito do Sistema Universidade Aberta do Brasil - UAB. As orientações metodológicas de Bourdieu (2007 foram um dos elementos orientadores na análise das entrevistas, considerando ainda o uso heurístico do conceito de habitus. Conclui-se que o habitus professoral envolve esforços voluntários em busca de uma ação pedagógica diferenciada. No entanto, ele é ambíguo e condescendente frente aos limites do modelo de EaD no âmbito da UAB. Ao fim, os dados analisados permitem fornecer elementos para reorientação político-pedagógica que vise a um novo modelo de EaD nacional.

  19. Entrevista com o professor Salomon Turnowski

    Directory of Open Access Journals (Sweden)

    Carolina Lima Vilela

    2014-01-01

    Full Text Available Com aproximadamente 50 anos de experiências profissionais variadas em Geografia, o Professor Salomon Turnowski se revela, até hoje, um apaixonado por nosso campo de conhecimento. Em entrevista realizada pela equipe da Revista Giramundo, em junho de 2009, na Unidade Escolar Humaitá II, a disposição de contar sua trajetória parece movida pelos comentários a respeito de nossa ciência, de suas transformações e de sua paixão pelos livros. Atuante no Colégio Pedro II, onde lecionou entre 1984 e 2009, no IBGE e na antiga FIDERJ (Fundação Instituto de Desenvolvimento do Estado do Rio de Janeiro, entre outros, seu depoimento se revela, portanto, uma oportunidade para conhecer um pouco mais sobre sujeitos e instituições voltados à construção da Geografia no Brasil e no Rio de Janeiro, assim como sobre os contrastes entre as vivências de geógrafos e de professor. Fica aqui o registro acerca da experiência valiosa e diversificada desse profissional, assim como uma singela homenagem.

  20. Entrevista com o professor Rafael Straforini

    Directory of Open Access Journals (Sweden)

    Demian Garcia Castro

    2015-07-01

    Full Text Available Com vivência profissional na Educação Básica e na Superior, além de experiência de pesquisa em diferentes instituições universitárias nos estados de São Paulo e do Rio de Janeiro, o professor Rafael Straforini pode ser considerado uma das novas vozes importantes na área do Ensino de Geografia. Assim como na edição anterior, uma vez mais utilizamo-nos de plataforma digital e, na conexão direta Rio-Campinas, tivemos a oportunidade de abordar questões como a Geografia na Educação Infantil e nas séries iniciais do Ensino Fundamental, o currículo e a formação de professores, além de aproveitar um pouco para conversar sobre Geografia Histórica e a Revista Brasileira de Educação em Geografia. Agradecemos a Straforini pela oportunidade e deixamos o leitor com o resultado desse encontro virtual.

  1. When Professors Don't Return Essays.

    Science.gov (United States)

    Feldman, William; Dhaliwal, Gurpreet

    2015-01-01

    Students devote hundreds of hours to writing notes during medical school clerkships but receive very limited feedback on that work. Medical student notes are like college essays-both are persuasive compositions. But attending physicians rarely scrutinize student notes like college professors analyze essays. This is a missed opportunity to teach clinical reasoning. A survey at our institution showed that only 16% of students received written feedback and 31% received oral feedback on their notes from more than 3 attending physicians during the first 8 months of 3rd-year clerkships. Many studies have reported a paucity of feedback across multiple domains and a sense among students that clinical reasoning is not being adequately taught during clerkships. Meanwhile, college professors teach written composition and reasoning through interactive methods that help students to develop structured, well-reasoned arguments. A recent study showed that 85% of Oxford undergraduates favored these demanding and time-intensive tutorials. Attending physicians who adopt a tutorial-based approach toward their students' notes would have a forum to teach clinical reasoning and emphasize the importance of written composition in medical practice.

  2. FORMANDO PROFESSORES: UMA HEURÍSTICA REFLEXIVA

    Directory of Open Access Journals (Sweden)

    Tania Gastão Saliés

    2011-03-01

    Full Text Available O presente estudo reflete criticamente sobre a formação do professor de LE à luz da condição pós-método, com o intuito de contribuir para a ação de programas de formação.  Dentre outras questões, ilumina a importância de o professor em formação construir percepção sobre o contexto e de si próprio como agente da própria formação.  Para tal, primeiro trata de aspectos filosóficos presentes no contra-discurso da condição pós-método, em seguida destaca a conscientização sobre o papel do contexto no ensino-aprendizagem de línguas e finalmente  apresenta uma heurística reflexiva com potencial de guiar as ações dos cursos de formação.    

  3. Low Impact Development Intensive Rural Construction Planning in Xu Fu Village Ningbo, China: Planning Review through Rural Resilience Perspective

    Directory of Open Access Journals (Sweden)

    Roosmayri Lovina Hermaputi

    2017-08-01

    Full Text Available Xu Fu Village Ningbo LID Intensive Rural Construction Planning is a cooperation project between Zhejiang University and Ningbo Institute of Technology which named "12th Five-Year National Science and Technology support program-the comprehensive demonstration of the key technology of the beautiful rural construction in the rapid urbanization area of the Yangtze River Delta". This plan focuses on intensive rural construction as part of rural development and construction project that applies the principles of low impact development. Xu Fu Village located in the Yangtze River Delta Region. Currently, the rural growth brings the high impact of development, as a result of rapid urbanization growth arising several issues, such as low land use efficiency, dispersed rural residence, homestead occupies more, rural roads covering over, etc. Meanwhile, Xu Fu village wishes to develop its tourism potential. Thus, the intensive rural construction should be done to avoid the severe effect. The project result hopefully can improve the quality and level of rural residential planning, design, and construction; improve their living environment; save construction land and water use; and improve energy efficiency. The aim of this study is to review the Low Impact Development (LID Intensive Rural Construction in Xu Fu Village, Ningbo City through the rural resilience perspective. This paper will describe the project plan first, then review it through rural resilience perspective. This paper will elaborate the rural resilience theory and then review the rural resiliency through two parts; the first part is identifying rural resilience in rural infrastructure development based on the criteria created by Ayyob S. and Yoshiki Y. (2014, about urban resiliency criteria, and then the second part is reviewing Xu Fu Village resilience through Arup Resilience Qualities (2012, considering three rural resilience domain (economy, ecology, and cultural.

  4. Professor Gender, Age, and “Hotness” in Influencing College Students’ Generation and Interpretation of Professor Ratings

    Directory of Open Access Journals (Sweden)

    Sara L. Sohr-Preston

    2016-09-01

    Full Text Available Undergraduate psychology students rated expectations of a bogus professor (randomly designated a man or woman and hot versus not hot based on an online rating and sample comments as found on RateMyProfessors.com (RMP. Five professor qualities were derived using principal components analysis (PCA: dedication, attractiveness, enhancement, fairness, and clarity. Participants rated current psychology professors on the same qualities. Current professors were divided based on gender (man or woman, age (under 35 or 35 and older, and attractiveness (at or below the median or above the median. Using multivariate analysis of covariance (MANCOVA, students expected hot professors to be more attractive but lower in clarity. They rated current professors as lowest in clarity when a man and 35 or older. Current professors were rated significantly lower in dedication, enhancement, fairness, and clarity when rated at or below the median on attractiveness. Results, with previous research, suggest numerous factors, largely out of professors’ control, influencing how students interpret and create professor ratings. Caution is therefore warranted in using online ratings to select courses or make hiring and promotion decisions.

  5. Professor Gender, Age, and “Hotness” in Influencing College Students’ Generation and Interpretation of Professor Ratings

    Directory of Open Access Journals (Sweden)

    Sara L. Sohr-Preston

    2016-09-01

    Full Text Available Undergraduate psychology students rated expectations of a bogus professor (randomly designated a man or woman and hot versus not hot based on an online rating and sample comments as found on RateMyProfessors.com (RMP. Five professor qualities were derived using principal components analysis (PCA: dedication, attractiveness, enhancement, fairness, and clarity. Participants rated current psychology professors on the same qualities. Current professors were divided based on gender (man or woman, age (under 35 or 35 and older, and attractiveness (at or below the median or above the median. Using multivariate analysis of covariance (MANCOVA, students expected hot professors to be more attractive but lower in clarity. They rated current professors as lowest in clarity when a man and 35 or older. Current professors were rated significantly lower in dedication, enhancement, fairness, and clarity when rated at or below the median on attractiveness. Results, with previous research, suggest numerous factors, largely out of professors’ control, influencing how students interpret and create professor ratings. Caution is therefore warranted in using online ratings to select courses or make hiring and promotion decisions. 

  6. Institutional Support for the Virtual Professor

    Directory of Open Access Journals (Sweden)

    Tom JONES

    2004-01-01

    Full Text Available Academics who hold positions at single-mode, distance education institutions are presently being hampered by an adherence to a long-standing set of protocols (specific office location, face-to-face meetings that were put in place when the conventional post-secondary was the norm. With the advent of a powerful merging of personal computers and the internet, a shift from those protocols to one of support for the virtual professor is in the offing, to the benefit of both the professoriate and the student. A key factor in this shift is the degree and quality of institutional support that will allow these changes to take place. This paper focuses on a number of the key factors that will have to be addressed if this new type of distance education academic is to function effectively.

  7. Rezension von: Ulf Gebken, Söhnke Vosgerau (Hg.: Fußball ohne Abseits. Ergebnisse und Perspektiven des Projekts ‚Soziale Integration von Mädchen durch Fußball‘. Wiesbaden: Springer VS 2014.

    Directory of Open Access Journals (Sweden)

    Robert Claus

    2014-12-01

    Full Text Available Seit 2006 wurden im Rahmen des vom Deutschen Fußball-Bund durchgeführten Modellprojektes „Soziale Integration von Mädchen durch Fußball“ an über 200 Standorten Schul-AGs in sogenannten Brennpunktbezirken aufgebaut. Im vorliegenden Sammelband beleuchten die Autor/-innen ausführlich die Funktion von Sport für die pädagogische Kompetenzvermittlung. Zudem erbringen sie einen umfassenden Projektbericht und leisten ein Plädoyer für die Modernisierung des Verhältnisses zwischen Schule und Vereinen, Lehrplan und Ehrenamt. Somit stellt das Buch, wie auch das Projekt, einen enorm wichtigen Beitrag zur Geschlechtergerechtigkeit im Sport dar. Gleichzeitig jedoch liest sich eine Reihe an Texten etwas zu sperrig für den Bericht einer Praxisforschung, und Begriffe im Feld der ‚Integration’ bleiben schwammig.

  8. A Reactor Development Scenario for the FuZE Sheared-Flow Stabilized Z-pinch

    Science.gov (United States)

    McLean, Harry S.; Higginson, D. P.; Schmidt, A.; Tummel, K. K.; Shumlak, U.; Nelson, B. A.; Claveau, E. L.; Forbes, E. G.; Golingo, R. P.; Stepanov, A. D.; Weber, T. R.; Zhang, Y.

    2017-10-01

    We present a conceptual design, scaling calculations, and development path for a pulsed fusion reactor based on a flow-stabilized Z-pinch. Experiments performed on the ZaP and ZaP-HD devices have largely demonstrated the basic physics of sheared-flow stabilization at pinch currents up to 100 kA. Initial experiments on the FuZE device, a high-power upgrade of ZaP, have achieved 20 usec of stability at pinch current 100-200 kA and pinch diameter few mm for a pinch length of 50 cm. Scaling calculations based on a quasi-steady-state power balance show that extending stable duration to 100 usec at a pinch current of 1.5 MA and pinch length of 50 cm, results in a reactor plant Q 5. Future performance milestones are proposed for pinch currents of: 300 kA, where Te and Ti are calculated to exceed 1-2 keV; 700 kA, where DT fusion power would be expected to exceed pinch input power; and 1 MA, where fusion energy per pulse exceeds input energy per pulse. This work funded by USDOE ARPA-E and performed under the auspices of Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344. LLNL-ABS-734770.

  9. Multi-Model Grand Ensemble Hydrologic Forecasting in the Fu River Basin Using Bayesian Model Averaging

    Directory of Open Access Journals (Sweden)

    Bo Qu

    2017-01-01

    Full Text Available Statistical post-processing for multi-model grand ensemble (GE hydrologic predictions is necessary, in order to achieve more accurate and reliable probabilistic forecasts. This paper presents a case study which applies Bayesian model averaging (BMA to statistically post-process raw GE runoff forecasts in the Fu River basin in China, at lead times ranging from 6 to 120 h. The raw forecasts were generated by running the Xinanjiang hydrologic model with ensemble forecasts (164 forecast members, using seven different “THORPEX Interactive Grand Global Ensemble” (TIGGE weather centres as forcing inputs. Some measures, such as data transformation and high-dimensional optimization, were included in the experiment after considering the practical water regime and data conditions. The results indicate that the BMA post-processing method is capable of improving the performance of raw GE runoff forecasts, yielding more calibrated and sharp predictive probability density functions (PDFs, over a range of lead times from 24 to 120 h. The analysis of percentile forecasts in two different flood events illustrates the great potential and prospects of BMA GE probabilistic river discharge forecasts, for taking precautions against severe flooding events.

  10. Chondroprotective Effects and Multitarget Mechanisms of Fu Yuan Capsule in a Rat Osteoarthritis Model

    Directory of Open Access Journals (Sweden)

    Li Zeng

    2017-01-01

    Full Text Available Fu Yuan Capsule (FYC has been clinically used for osteoarthritis (OA and its related diseases for many years in China. However, its pharmacological mechanism remains unclear. This study aimed to investigate the potential chondroprotective effects of FYC on articular cartilage. Rat OA model was induced by anterior cruciate ligament transection. A group of rats was treated with FYC for 12 weeks. Joint structure, types I and II collagen, and proteoglycan were evaluated by histological examination. The expression of C-terminal crosslinking telopeptide of type II collagen, hydroxyproline, a disintegrin and metalloproteinase with thrombospondin motifs, matrix metalloproteinase, interleukin-1 beta, nitric oxide, prostaglandin E2, heat-shock protein 70, transforming growth factor-beta, osteoprotegerin, and receptor activator of nuclear factor κB ligand were detected. Treatment with FYC could protect against articular cartilage injury. FYC treatment significantly decreased the extracellular matrix degradation factors and inflammatory mediators. Moreover, articular cartilage protective factors were increased in the FYC group. The current finding suggests that FYC protects articular cartilage in a rat OA model through various ways. Thus, it may be an effective agent for OA treatment.

  11. Jin Fu Kang Oral Liquid Inhibits Lymphatic Endothelial Cells Formation and Migration

    Directory of Open Access Journals (Sweden)

    Hai-Lang He

    2016-01-01

    Full Text Available Lung cancer is the leading cause of cancer-related deaths worldwide. Jin Fu Kang (JFK, an oral liquid prescription of Chinese herbal drugs, has been clinically available for the treatment of non-small cell lung cancer (NSCLC. Lymphangiogenesis is a primary event in the process of cancer development and metastasis, and the formation and migration of lymphatic endothelial cells (LECs play a key role in the lymphangiogenesis. To assess the activity of stromal cell-derived factor-1 (SDF-1 and the coeffect of SDF-1 and vascular endothelial growth factor-C (VEGF-C on the formation and migration of LECs and clarify the inhibitory effects of JFK on the LECs, the LECs were differentiated from CD34+/VEGFR-3+ endothelial progenitor cells (EPCs, and JFK-containing serums were prepared from rats. SDF-1 and VEGF-C both induced the differentiation of CD34+/VEGFR-3+ EPCs towards LECs and enhanced the LECs migration. Couse of SDF-1 and VEGF-C displayed an additive effect on the LECs formation but not on their migration. JFK inhibited the formation and migration of LECs, and the inhibitory effects were most probably via regulation of the SDF-1/CXCR4 and VEGF-C/VEGFR-3 axes. The current finding suggested that JFK might inhibit NSCLC through antilymphangiogenesis and also provided a potential to discover antilymphangiogenesis agents from natural resources.

  12. Die Osteonekrose des Fußes: Eine Übersicht

    Directory of Open Access Journals (Sweden)

    Schenk S

    2007-01-01

    Full Text Available Die Osteonekrose (ON am Fuß ist eine heterogene Gruppe von Krankheitsbildern, die sich deutlich hinsichtlich Klinik, Verlauf, Prädilektionsalter und Prognose unterscheiden. Ebenso sind die Ursachen für diese Erkrankungen vielfältig: Neben idiopathischen finden sich auch posttraumatische und postoperative Formen. Seltene Ursachen sind Kollagenosen, Stoffwechselerkrankungen wie Diabetes mellitus und Kortikoidtherapie. ON finden sich gehäuft nach Nierentransplantationen. Je nach Ursache tritt eine ON gehäuft in typischer Lokalisation auf. Idiopathische Formen findet man am Os naviculare pedis – Morbus Köhler 1 (MK1, an den Metatarsaleköpfchen – Morbus Köhler 2, "Freiberg’s disease" (MK2, an den Sesambeinen und an der Apophyse des Calcaneus. Operationsbedingte Fälle sind gehäuft am Metatarsaleköpfchen 1 nach Versorgung eines Hallux valgus lokalisiert, posttraumatische Nekrosen am Talus. In diesem Artikel werden die idiopathischen Formen hinsichtlich Klinik und Therapie näher beleuchtet. Bezüglich der Therapie gibt es konservative und operative Ansätze. Die wissenschaftlichen Daten zur Behandlung von idiopathischen Nekrosen sind spärlich, die Behandlungsstrategien jedoch einheitlich und allgemein anerkannt.

  13. Students' Needs Analysis in an EFL Program for University Professors

    Science.gov (United States)

    Bedoya, Paula Andrea; Valencia, Luz María; Montoya, Juan Carlos

    2016-01-01

    This study sets out to investigate professors' needs from an English as a foreign language program in a public university regarding demands, interests, and lacks based on the methodology of needs analysis. Data collected through a survey, focus groups, and individual interviews showed that professors need to meet the institutional language policy…

  14. Rate My Professor: Online Evaluations of Psychology Instructors

    Science.gov (United States)

    Silva, Kathleen M.; Silva, Francisco J.; Quinn, Megan A.; Draper, Jill N.; Cover, Kimberly R.; Munoff, Alison A.

    2008-01-01

    We analyzed students' ratings and comments of their psychology instructors that were posted on RateMyProfessors.com and RateMyProfessors.ca to determine which features of a course and an instructor evoked the most positive and negative reactions. A content analysis of students' comments showed that instructors' characteristics(e.g., enthusiastic,…

  15. More Colleges Offer Part-Time Options for Professors

    Science.gov (United States)

    Wilson, Robin

    2008-01-01

    The University of California campuses are among a small but growing number of research universities adopting new policies--or reinvigorating old ones--that allow tenure-track and tenured professors to work part time. Typically, professors interested in scaling back their work want more time to care for young children, a sick relative, or an aging…

  16. Child Rearing as a Career Impediment to Women Assistant Professors.

    Science.gov (United States)

    Finkel, Susan Kolker; Olswang, Steven G.

    1996-01-01

    Over 40% of women assistant professors in a recent survey (n=124) identified publishing, teaching, committees, and "time required by children" as serious impediments to achieving tenure, many more than reported sexual harassment and sexism as serious obstacles. Policy changes that will accommodate women professors' time commitments to…

  17. Do Professors Have Customer-Based Brand Equity?

    Science.gov (United States)

    Jillapalli, Ravi K.; Jillapalli, Regina

    2014-01-01

    This research endeavors to understand whether certain professors have customer-based brand equity (CBBE) in the minds of students. Consequently, the purpose of this study is to conceptualize, develop, and empirically test a model of customer-based professor brand equity. Survey data gathered from 465 undergraduate business students were used to…

  18. Academic Labor Markets and Assistant Professors' Employment Outcomes

    Science.gov (United States)

    Hargens, Lowell L.

    2012-01-01

    Using data for 638 assistant professors who joined graduate sociology departments between 1975 and 1992, I examine the claim that when the labor market for new doctorates is weak, assistant professors experience less favorable employment outcomes than when that labor market is strong. Surprisingly, I find that those hired during the weak…

  19. Effects of Social Support on Professors' Work Stress

    Science.gov (United States)

    Moeller, Christin; Chung-Yan, Greg A.

    2013-01-01

    Purpose: The purpose of this paper is to examine how various types of workplace social support from different support sources interact with occupational stressors to predict the psychological well-being of university professors. Design/method/approach: A total of 99 full-time professors participated via an online or paper questionnaire. Findings:…

  20. Mentoring by the Community College Professor: One Role among Many

    Science.gov (United States)

    Galbraith, Michael; James, Waynne

    2004-01-01

    The process of mentorship in relationship to the community college professor and the potential to improve and enhance the teaching and learning process is explored in this article. This article suggests that not all community college professors are psychological or intellectually disposed to being or becoming a good mentor. It is put forth that…

  1. 26 CFR 521.114 - Visiting professors or teachers.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 19 2010-04-01 2010-04-01 false Visiting professors or teachers. 521.114... of Denmark and of Danish Corporations § 521.114 Visiting professors or teachers. Under Article XIV of... States for the purpose of teaching, lecturing, or instructing at any university, college, school, or...

  2. Mental Health Assessment in Professors' Training in Two Chilean Universities

    Science.gov (United States)

    Ossa, Carlos J.; Quintana, Ingrid M.; Rodriguez, Felipe F.

    2015-01-01

    This study analyzed the evaluation of professors of pedagogy and directors programs, about the importance of mental health in vocational training, and factors that might influence this valuation. The methodology includes participation of 17 academicians (professors and belonging to the managerial staff) of two universities in southern Chile. A…

  3. Differentiated Instruction: Are University Reading Professors Implementing It?

    Science.gov (United States)

    Williams-Black, Thea Hayes; Bailey, Jennifer P.; Lawson, Pamela D. Coleman

    2010-01-01

    This qualitative study surveyed university professors of literacy education to explore "how" and "if" they modeled differentiated instruction in their own college classrooms. A survey in questionnaire format on "how" and "if" University Reading Professors differentiate instruction was sent to a purposeful…

  4. University Pedagogy for Assistant Professors at Aalborg University (Part 2)

    DEFF Research Database (Denmark)

    Kolmos, Anette; Krogh, Lone

    2003-01-01

    In issue 1-2003, Anette Kolmos and Lone Krogh reported on the two-semester study course " University Pedagogy for Assistant Professors at Aalborg University (DK)". Now, in part 2, they are adressing guidelines for supervison and advising of assistant professors in the university teacher education...

  5. Student and Professor Gender Effects in Introductory Business Statistics

    Science.gov (United States)

    Haley, M. Ryan; Johnson, Marianne F.; Kuennen, Eric W.

    2007-01-01

    Studies have yielded highly mixed results as to differences in male and female student performance in statistics courses; the role that professors play in these differences is even less clear. In this paper, we consider the impact of professor and student gender on student performance in an introductory business statistics course taught by…

  6. Effect of viscous additives on the absorption and hepatic disposition of 5-fluorouracil (5-FU) after application to liver surface in rats.

    Science.gov (United States)

    Kodama, Yukinobu; Horishita, Miyuki; Fumoto, Shintaro; Mine, Toyoharu; Miyamoto, Hirotaka; Yoshikawa, Naoki; Hirata, Haruna; Sasaki, Hitoshi; Nakamura, Junzo; Nishida, Koyo

    2012-10-01

    Objectives  The aim was to study the effect of viscous additives on the absorption and hepatic disposition of 5-fluorouracil (5-FU) after application to the liver surface in rats. Methods  5-FU solution with or without viscous additives was applied to the rat liver surface with a cylindrical diffusion cell. Then, blood and the remaining solution in the diffusion cell were collected at selected times, followed by excision of the liver. The excised liver was divided into three sites and assayed for 5-FU content. Key findings  The absorption rate of 5-FU from the liver surface was decreased in the presence of carboxymethylcellulose sodium (CMC-Na) and polyvinyl alcohol (PVA) as compared with the control. The k(a) values of PVA 15% and CMC-Na 1% were reduced to about 80 and 67% of the control. The maximum plasma concentration of 5-FU was decreased by incorporation of viscous additives. The 5-FU concentration at the diffusion cell attachment site of the liver (site 1) plateaued at 180 min in the absence of viscous additives. On the other hand, the concentration of 5-FU at site 1 increased in a time-dependent manner until 360 min in the presence of viscous additives. Conclusion  Viscous additives might be useful for retaining drugs at their application site and controlling the rate of absorption from the liver surface. © 2012 The Authors. JPP © 2012 Royal Pharmaceutical Society.

  7. In commemoration of professor V.P. Karpov

    Directory of Open Access Journals (Sweden)

    Semyonova L.S.

    2013-10-01

    Full Text Available This article is about professor Karpov V.P., a prominent scientist, first rector of Yekaterinoslav Medical Academy. Biography of a great investigator, his main achievements in the area of histology, biology, theory and history of medicine was studied. Professor Karpov V.P. always combined his great scientific, organizational and research work with social activity. Monographs of professor Karpov V.P. and conferences organized by him were of great importance in the solution of such new problems as theary of microscope and cell amitosis. Professor Karpov is a founder of a large school of histology. Thanks to his active participation and personal guidance, in 1917 department of histology was founded in Yekaterinoslav Medical Institute. The author of the article has analyzed Hippocrates` works translated into Russian by professor Karpov V.P. and pointed out their significance for modern medical science and practice.

  8. Professor I I Glass A Tribute and Memorial

    CERN Document Server

    Igra, Ozer

    2013-01-01

    The book provides personal memories along with description of scientific works written by ex-graduate students and research associates of the late Professor Glass. The described research work covers a wide range of shock wave phenomena, resulting from seeds planted by Professor Glass. Professor Glass was born in Poland in 1918. He immigrated together with his parents to Canada at the age of 12 and received all his professional education at the University of Toronto, Canada. He became a world recognized expert in shock wave phenomena, and during his 45 years of active research he supervised more than 125 master and doctoral students, post-doctoral fellows and visiting research associates. In this book seven of his past students/research-associates describe their personal memories of Professor Glass and present some of their investigations in shock wave phenomena which sprung from their past work with Professor Glass. Specifically, these investigations include underwater shock waves, shock/bubble interaction, m...

  9. Extracellular Disposal of Tumor-Suppressor miRs-145 and -34a via Microvesicles and 5-FU Resistance of Human Colon Cancer Cells

    Directory of Open Access Journals (Sweden)

    Yukihiro Akao

    2014-01-01

    Full Text Available The dysregulation of microRNA (miRNA expression causes various kinds of diseases. Especially, alterations in miRNA expression levels are frequently observed in human tumor cells and are associated with cancer pathogenesis. Earlier we established Fluorouracil (5-FU-resistant human colon cancer DLD-1 cells (DLD-1/5FU from parental 5-FU- sensitive DLD-1 cells. In the present study, we examined the expression of miRNA in each cell line and in its extracellular microvesicles (MVs before and after treatment with 5-FU. The nascent RNAs of anti-oncogenic miR-34a and -145 labeled with EU in both cells were proved to be transferred into MVs in both cell lines. The levels of miR-34a and -145 in the cells and in their MVs were not largely different in the two cell lines, and a substantial amount of both miRNAs was secreted by both cell lines even in the steady-state condition. The exposure of both cell lines to 5-FU significantly increased the intracellular levels of miR-145 and miR-34a in the 5-FU-sensitive DLD-1 cells, whereas the level of neither miR was elevated in the DLD-1/5FU cells. Interestingly, the amount of miR-145 detected in the small MVs shed into the medium of the parental cells was reduced after the treatment with 5-FU. On the other hand, the intracellular expression of miR-34a in the DLD-1/5FU cells was down-regulated compared with that in the parental DLD-1 cells even in the steady-state condition. As to the miR-34a secreted into MVs, the increase in the level in DLD-1/5FU cells was greater than that in the parental DLD-1 cells after the treatment with 5-FU. Thus, the intra- and extracellular miR-145 and -34a were closely associated with 5-FU resistance, and the resistance was in part due to the enhanced secretion of miR-145 and -34a via MVs, resulting in low intracellular levels of both miRNAs.

  10. Stevens-Johnson Syndrome Patient Received Combination Chemotherapy Gemcitabine, Cisplatin, and 5-FU for Biliary Tract Cancer.

    Science.gov (United States)

    Aznab, Mozaffar; Khazaei, Mansour

    2016-06-01

    Stevens-Johnson syndrome has been an acute, usually self-limiting disease of the skin and mucous membranes. This case report has presented an evidence of the development Stevens - Johnson syndrome associated with combination chemotherapy administration of 5FU, gemcitabin and cisplatin in a patient with biliary tract cancer. Our case was a 54-year-old woman patient, a case of biliary tract cancer who has developed more severe symptoms of Stevens-Johnson syndrome. Diagnosis has confirmed by skin biopsy of an affected area .The patient has improved with supportive care, and during 25 day occurred recovery. Although Stevens-Johnson syndrome has been a rare toxicity, physicians should pay a special attention to the monitoring of biliary tract cancer patients on combination chemotherapy with 5FU, cisplatin and gemcitabin.

  11. OBITUARY: Professor Jan Evetts in memoriam

    Science.gov (United States)

    Dew-Hughes, David; Campbell, Archie; Glowacki, Bartek

    2005-11-01

    It is with great sadness that we report the death of Jan Evetts, who lost his second battle with cancer on 18 August 2005. In 1988 he was appointed Founding Editor of this journal where his leadership created the foundation upon which its success rests today. He made an outstanding series of contributions to the science of superconductivity and to the understanding of superconducting materials, and was an indefatigable champion of the development of applications of superconductivity. The loss to the scientific community is incalculable, as is attested by the many communications received from colleagues throughout the world. Professor Jan Edgar Evetts (1939-2005) Professor Jan Edgar Evetts (1939-2005) Jan was born on 31 March 1939, and attended the Dragon School in Oxford, and later Haileybury. He was awarded an exhibition to read Natural Sciences at Pembroke College, Cambridge in 1958 and took his BA degree in 1961. He then undertook a Certificate of Postgraduate Study in Physics under the supervision of Professor Neville Mott. He was the first student to undertake this newly-instituted course; the title of his thesis was `The Resistance of Transition Metals'. In 1962 he joined David Dew-Hughes' embryonic superconducting materials research group, along with Archie Campbell and Anant Narlikar. In fact it was Jan's enthusiasm for the proposed course of research that helped convince David that he should follow Professor Alan Cottrell's suggestion to apply metallurgical methodology to the study of the factors that controlled critical current density in the type II superconductors that were then under development for applications in magnets. Competing theories for the critical current density at that time were fine filaments or `Mendelssohn Sponge' versus the pinning of Abrikosov quantized vortices. The results of the group's work, to which Jan made a major contribution, came down heavily in favour of the latter theory. Jan's outstanding characteristic was his

  12. Enteric coated HPMC capsules plugged with 5-FU loaded microsponges: a potential approach for treatment of colon cancer

    Directory of Open Access Journals (Sweden)

    Ankita Gupta

    2015-09-01

    Full Text Available The work was aimed at developing novel enteric coated HPMC capsules (ECHC plugged with 5 Florouracil (5-FU loaded Microsponges in combination with calcium pectinate beads. Modified quasi-emulsion solvent diffusion method was used to formulate microsponges based on 32 factorial design and the effects of independent variables (volume of organic solvent and Eudragit RS100 content on the dependent variables (Particle size, %EE & % CDR were determined. The optimized microsponges (F4 were characterized by SEM, PXRD, TGA and were plugged along with calcium pectinate beads in HPMC capsules and the HPMC capsules were further coated with enteric polymer Eudragit L 100 (Ed-L100 and/ or Eudrgit S 100 (Ed-S 100 in different proportions. In vitro release study of ECHC was performed in various release media sequentially SGF for 2 h, followed by SIF for the next 6 h and then in SCF (in the presence and absence of pectinase enzyme for further 16 h. Drug release was retarded on coating with EdS-100 in comparison to blend of EdS-100: EdL-100 coating. The percentage of 5-FU released at the end of 24 h from ECHC 3 was 97.83 ± 0.12% in the presence of pectinase whereas in control study it was 40.08 ± 0.02% drug. The optimized formulation was subjected to in vivo Roentgenographic studies in New Zealand white rabbits to analyze the in vivo behavior of the developed colon targeted capsules. Pharmacokinetic studies in New Zealand white rabbits were conducted to determine the extent of systemic exposure provided by the developed formulation in comparison to 5-FU aqueous solutions. Thus, enteric coated HPMC capsules plugged with 5-FU loaded microsponges and calcium pectinate beads proved to be promising dosage form for colon targeted drug delivery to treat colorectal cancer.

  13. Impacto vocal de professores Teachers' vocal impact

    Directory of Open Access Journals (Sweden)

    Adriana Ricarte

    2011-08-01

    Full Text Available OBJETIVO: analisar o impacto vocal nas atividades diárias em professores do ensino médio. Correlacionar os achado da auto-percepção do problema vocal com os aspectos: efeitos no trabalho, na comunicação diária, na comunicação social e na sua emoção. MÉTODOS: a amostra foi constituída por 107 professores, sendo 86 com queixa e 21 sem queixa, selecionados em escolas da rede particular de ensino de Maceió-AL. Cada professor respondeu individualmente o protocolo Perfil Participação em Atividades Vocais na presença da pesquisadora, assinalando suas respostas em uma escala visual que varia de 0 a 10. O protocolo é composto por 28 questões com a presença integrada em cinco aspectos englobados para avaliar a qualidade de vida e o resultado de tratamentos vocais. O protocolo oferece, ainda, dois escores adicionais: pontuação de limitação nas atividades (PLA e de restrição de participação (PRP. RESULTADOS: na comparação dos grupos com e sem queixa vocal foram verificados que todos os resultados foram estatisticamente significantes (pPURPOSE: to analyze the vocal impact in the daily activities on high-school teachers. Correlate the finding of the auto-perception on the vocal problem with the following aspects: effects in the work, daily communication, social communication and, its emotion METHODS: the sample consisted of 107 teachers, 86 with and 21 with no complaint, selected from private teaching schools in Maceió-AL. Each teacher answered individually the Protocol for Voice Activity Participation Profile in the presence of the researcher, noting their responses on a visual scale ranging from 0 to 10. The protocol is composed of 28 questions with the presence integrated in five aspects to evaluate the quality of life and the result of vocal treatments. The protocol offers, still, two additional scores: punctuation of limitation in the activities (PLA and restriction of participation (PRP. RESULTS: comparing the groups with

  14. Producing High-Performance, Stable, Sheared-Flow Z-Pinches in the FuZE project

    Science.gov (United States)

    Golingo, R. P.; Shumlak, U.,; Nelson, B. A.; Claveau, E. L.; Forbes, E. G.; Stepanov, A. D.; Weber, T. R.; Zhang, Y.; McLean, H. S.; Tummel, K. K.; Higginson, D. P.; Schmidt, A. E.; University of Washington (UW) Collaboration; Lawrence Livermore National Laboratory (LLNL) Collaboration

    2017-10-01

    The Fusion Z-Pinch Experiment (FuZE) has made significant strides towards generating high-performance, stable Z-pinch plasmas with goals of ne = 1018 cm-3 and T =1 keV. The Z-pinch plasmas are stabilized with a sheared axial flow that is driven by a coaxial accelerator. The new FuZE device has been constructed and reproduces the major scientific achievements the ZaP project at the University of Washington; ne = 1016 cm-3,T = 100 eV, r20 μs. These parameters are measured with an array of magnetic field probes, spectroscopy, and fast framing cameras. The plasma parameters are achieved using a small fraction of the maximum energy storage and gas injection capability of the FuZE device. Higher density, ne = 5×1017 cm-3, and temperature, T = 500 eV, Z-pinch plasmas are formed by increasing the pinch current. At the higher voltages and currents, the ionization rates in the accelerator increase. By modifying the neutral gas profile in the accelerator, the plasma flow from the accelerator is maintained, driving the flow shear. Formation and sustainment of the sheared-flow Z-pinch plasma will be discussed. Experimental data demonstrating high performance plasmas in a stable Z-pinches will be shown. This work is supported by an award from US ARPA-E.

  15. Protective Effect of Shen-Fu Injection on Neuronal Mitochondrial Function in a Porcine Model of Prolonged Cardiac Arrest

    Directory of Open Access Journals (Sweden)

    Wei Gu

    2014-01-01

    Full Text Available Background. Shen-Fu injection (SFI following cardiac arrest exhibits neurological effects, but its effect on neurological dysfunction is unclear. This study sought to investigate the protective effect of SFI on nerve cells in a porcine model of cardiac arrest. Methods. After eight minutes of untreated ventricular fibrillation (VF and 2 minutes of basic life support, 24 pigs were randomized and divided into three cardiopulmonary resuscitation groups, which received central venous injection of either Shen-Fu (SFI group; 1.0 ml/kg, epinephrine (EP group; 0.02 mg/kg, or saline (SA group. Surviving pigs were sacrificed at 24 h after ROSC and brains were removed for analysis for morphologic changes of mitochondria by electron microscopy, for mitochondrial transmembrane potential (MTP by flow cytometry, and for opening of the mitochondrial permeability transition pore (MPTP by mitochondrial light scattering. Results. Compared with the EP and SA groups, SFI treatment reduced opening of MPTP, showing higher MMP. In addition, animals treated with SFI showed slight cerebral ultrastructure damage under the electron microscopy. Conclusion. Shen-Fu injection alleviated brain injury, improved neurological ultrastructure, stabilized membrane potential, and inhibited opening of MPTP. Therefore, SFI could significantly attenuate postresuscitation cerebral ischemia and reperfusion injury by modulating mitochondrial dysfunction of nerve cells.

  16. Spectral energy distribution analysis of class I and class II FU Orionis stars

    Energy Technology Data Exchange (ETDEWEB)

    Gramajo, Luciana V.; Gómez, Mercedes [Observatorio Astronómico, Universidad Nacional de Córdoba, Argentina, Laprida 854, 5000 Córdoba (Argentina); Rodón, Javier A., E-mail: luciana@oac.uncor.edu, E-mail: mercedes@oac.uncor.edu, E-mail: jrodon@eso.org [European Southern Observatory, Alonso de Córdova 3107, Vitacura, Casilla 19001, Santiago 19 (Chile)

    2014-06-01

    FU Orionis stars (FUors) are eruptive pre-main sequence objects thought to represent quasi-periodic or recurring stages of enhanced accretion during the low-mass star-forming process. We characterize the sample of known and candidate FUors in a homogeneous and consistent way, deriving stellar and circumstellar parameters for each object. We emphasize the analysis in those parameters that are supposed to vary during the FUor stage. We modeled the spectral energy distributions of 24 of the 26 currently known FUors, using the radiative transfer code of Whitney et al. We compare our models with those obtained by Robitaille et al. for Taurus class II and I sources in quiescence periods by calculating the cumulative distribution of the different parameters. FUors have more massive disks: we find that ∼80% of the disks in FUors are more massive than any Taurus class II and I sources in the sample. Median values for the disk mass accretion rates are ∼10{sup –7} M {sub ☉} yr{sup –1} versus ∼10{sup –5} M {sub ☉} yr{sup –1} for standard young stellar objects (YSOs) and FUors, respectively. While the distributions of envelope mass accretion rates for class I FUors and standard class I objects are similar, FUors, on average, have higher envelope mass accretion rates than standard class II and class I sources. Most FUors (∼70%) have envelope mass accretion rates above 10{sup –7} M {sub ☉} yr{sup –1}. In contrast, 60% of the classical YSO sample has an accretion rate below this value. Our results support the current scenario in which changes experimented by the circumstellar disk explain the observed properties of these stars. However, the increase in the disk mass accretion rate is smaller than theoretically predicted, although in good agreement with previous determinations.

  17. In Memory of Professor Mohammad Hossein Salehi 1941-2014

    Directory of Open Access Journals (Sweden)

    Reza Bagheri

    2014-05-01

    Full Text Available Unfortunately, last winter, we lost one of the leaders of Radiotherpy-Oncology in Iran, Professor Mohammad Hossein Salehi. He was an excellent teacher, a supportive friend and an experienced physician.Professor Salehi was born on April 21, 1941 in Shirvan. After graduating from high school, he continued his education in Mashhad Medical School. In 1968 he completed Medical School and began the Residency Program of Radiology in Mashhad Medical School. Soon after, due to the lack of Radiotherapists in Mashhad and his eager to set up a Radiotherapy services in Mashhad, Dr. Salehi moved to England. He passed the Residency of Radiotherapy from 1972 to 1975 in the Royal Marsden Hospital, London and earned his Diploma in Medical Radiotherapy (D.M.R.T from the England Royal College and finished his fellowship ( F.R.C.R. After moving back to Iran in the same year and acquiring the Iranian National Board of Radiology, he started to work as Assistant Professor of Radiotherapy in Ghaem Hospital, Mashhad University of Medical Sciences, Iran. He arranged and established the first Radiotherapy Department in Mashhad in 1976. He was the Head of Radiotherapy-Oncology Department from 1976 to 2006.He was appointed as Associate Professor and after Professor of Radiotherapy-Oncology in 1985 and 1993, respectively. Professor Salehi was an active member of the Iranian National Board of Radiotherapy for 30 years. He was awarded as” The Best Professor “for 3 times.Beside his valuable clinical and educational activities, he was interested in medical research. He has published more than 20 articles and supervised about 25 theses. After 40 years continuous activity, Professor Salehi was retired in 2010. Unfortunately Professor Salehi passed away on January 23, 2014 after a four-year battle with metastatic colon cancer. His strength, wisdom, guidance and kindness will be missed by all who knew him.

  18. Interview with Professor Karl-Heinz Mehlan.

    Science.gov (United States)

    Neumann, H G

    1991-09-01

    Professor Karl-Heinz Mehlan, one of the founding fathers of German family planning in the post WWII area, celebrated his 75th birthday of July 18, 1991. The celebration took place in Rostock and Dr. Mehlan was in the best of health. As part of the occasion, Dr. Hans-Georg Neumann conducted an interview with Dr. Mehlan about the beginnings of family planning in what was then the Soviet occupied zone of Germany as well as its further development up to the present day. In the course of the interview Dr. Mehlan discussed the history of abortion in East Germany during the period of recovery immediately after WWII. He related his experiences working as a general practitioner in Calau and the committees he served on that were related to the study and delivery of abortion. During this time there were 80,000 recorded cases. After this he went to Berlin to the Institut fur Sozialmedizin der Chartie to write about the Calau experience. This was the 1st time that the abortion problem was discussed in German in a scientific context. He studied mortality, morbidity, and after effects.

  19. Editorial: A dedication to Professor Jan Evetts

    Science.gov (United States)

    Weber, Harald; Dew-Hughes, David; Campbell, Archie; Barber, Zoe; Somekh, Rob; Glowacki, Bartek

    2006-03-01

    A few days before the beginning of the 7th European Conference on Applied Superconductivity we learned that Professor Jan Evetts, a pioneer of superconductor research, a brilliant scientist, a wonderful person and a great personal friend, had passed away. We therefore decided to dedicate the 7th European Conference on Applied Superconductivity to the memory of Jan Evetts. The following citation is based on material provided by his former supervisor (D Dew-Hughes) and his closest co-workers in Cambridge. Professor Jan Edgar Evetts (1939-2005) Professor Jan Edgar Evetts (1939-2005) Jan Evetts passed away after losing his second battle with cancer on 24th August 2005. He made an outstanding series of contributions to the science of superconductivity and to the understanding of superconducting materials and was an indefatigable champion of the development of applications of superconductivity. The loss to the superconductivity community is incalculable, as attested by the many communications received from colleagues throughout the world. Jan was born on 31 March 1939, and attended the Dragon School in Oxford, and later Haileybury. He was awarded an exhibition to read Natural Sciences at Pembroke College, Cambridge. He entered the college in 1958 and took his BA degree in 1961. He then undertook a Certificate of Postgraduate Study in Physics under the supervision of Professor Neville Mott. He was the first student to undertake this newly-instituted course; the title of his thesis was `The Resistance of Transition Metals'. In 1962 he joined David Dew-Hughes' superconducting materials research group, along with Archie Campbell and Anant Narlikar. In fact it was Jan's enthusiasm for the proposed course of research that helped convince David that he should follow Professor Alan Cottrell's suggestion to apply metallurgical methodology to the study of the factors that controlled critical current density in the type II superconductors that were then under development for

  20. Professor M.K. Vainu Bappu (1927-82)

    Science.gov (United States)

    West, R. M.

    1982-12-01

    It was with great sadness that we received the news of the death, on 19 August 1982, of Professor M.K.V. Bappu, President of the International Astronomical Union and Director of the Indian Institute of Astrophysics, Bangalore, India. Professor Bappu was spending a few months with ESO in Munich, doing research within solar and stellar spectroscopy and at the same time preparing for the XVIIIth IAU General Assembly. A heart ailment necessitated a major surgical intervention, which was apparently successful. Howeyer, post-operative complications set in, and after a heroic struggle, assisted by the foremost medical expertise, Professor Bappu expired in the early evening of 19 August.

  1. Professor perceptions of college students with attention deficit hyperactivity disorder.

    Science.gov (United States)

    Vance, Teresa Ann; Weyandt, Lisa

    2008-01-01

    From April to June 2005, the authors investigated professor perceptions of college students with attention deficit hyperactivity disorder (ADHD). 253 participants completed the ADHD Beliefs Survey-Revised, a 40-question survey measuring professor perceptions of ADHD. Analysis of variance measured false and reasonable beliefs related to ADHD. Results indicated that professors with differing levels of education, years of teaching experience, colleges in the university or community college, previous experiences with a student with ADHD, and ADHD training did not differ significantly in perceptions regarding general ADHD knowledge or college students with ADHD.

  2. [Study of the immunological mechanism of anti-tumor effects of 5-FU by establishing EL4 tumor-bearing mouse models].

    Science.gov (United States)

    Li, Mo-Lin; Li, Chuan-Gang; Shu, Xiao-Hong; Li, Ming-Xia; Jia, Yu-Jie; Qin, Zhi-Hai

    2007-11-01

    To investigate the immunological mechanism of anti-tumor effect of 5-FU by establishing lymphoma EL4 tumor-bearing mouse models in wild type C57BL/6 mice and nude C57BL/6 mice, respectively. The mouse lymphoma EL4 cells were inoculated subcutaneously into wild type C57BL/6 mice (immune-competent mice). Twelve days later, 5-FU of different doses was administered intraperitoneally to treat these wild type C57BL/6 tumor-bearing mice. The size of tumors in the wild type C57BL/6 mice was observed and recorded to explore the minimal dose of 5-FU that could cure the tumor-bearing mice. Then the same amount of EL4 tumor cells was inoculated subcutaneously into wild type C57BL/6 mice and nude C57BL/6 mice (T cell-deficient mice) simultaneously, which had the same genetic background of C57BL/6. Twelve days later, 5-FU of the minimal dose was given intraperitoneally to treat both the wild type and nude C57BL/6 tumor-bearing mice. The size of tumors in the two different types of mice was observed and recorded. A single dose of 5-FU (75 mg/kg) cured both the EL4 tumor-bearing wild type C57BL/6 mice and the EL4 tumor-bearing nude C57BL/6 mice in the first week. Two weeks after 5-FU treatment, all of the nude mice died of tumor relapse while most of the wild type C57BL/6 mice were fully recovered. A single dose of 5-FU has marked anti-tumor effects on lymphoma EL4 tumor-bearing C57BL/6 mice with or without T lymphocytes. The relapse of tumors after 5-FU treatment might be related to the function of T lymphocytes.

  3. Pharmacoeconomic analysis of adjuvant oral capecitabine vs intravenous 5-FU/LV in Dukes' C colon cancer: the X-ACT trial

    Science.gov (United States)

    Cassidy, J; Douillard, J-Y; Twelves, C; McKendrick, J J; Scheithauer, W; Bustová, I; Johnston, P G; Lesniewski-Kmak, K; Jelic, S; Fountzilas, G; Coxon, F; Díaz-Rubio, E; Maughan, T S; Malzyner, A; Bertetto, O; Beham, A; Figer, A; Dufour, P; Patel, K K; Cowell, W; Garrison, L P

    2006-01-01

    Oral capecitabine (Xeloda®) is an effective drug with favourable safety in adjuvant and metastatic colorectal cancer. Oxaliplatin-based therapy is becoming standard for Dukes' C colon cancer in patients suitable for combination therapy, but is not yet approved by the UK National Institute for Health and Clinical Excellence (NICE) in the adjuvant setting. Adjuvant capecitabine is at least as effective as 5-fluorouracil/leucovorin (5-FU/LV), with significant superiority in relapse-free survival and a trend towards improved disease-free and overall survival. We assessed the cost-effectiveness of adjuvant capecitabine from payer (UK National Health Service (NHS)) and societal perspectives. We used clinical trial data and published sources to estimate incremental direct and societal costs and gains in quality-adjusted life months (QALMs). Acquisition costs were higher for capecitabine than 5-FU/LV, but higher 5-FU/LV administration costs resulted in 57% lower chemotherapy costs for capecitabine. Capecitabine vs 5-FU/LV-associated adverse events required fewer medications and hospitalisations (cost savings £3653). Societal costs, including patient travel/time costs, were reduced by >75% with capecitabine vs 5-FU/LV (cost savings £1318), with lifetime gain in QALMs of 9 months. Medical resource utilisation is significantly decreased with capecitabine vs 5-FU/LV, with cost savings to the NHS and society. Capecitabine is also projected to increase life expectancy vs 5-FU/LV. Cost savings and better outcomes make capecitabine a preferred adjuvant therapy for Dukes' C colon cancer. This pharmacoeconomic analysis strongly supports replacing 5-FU/LV with capecitabine in the adjuvant treatment of colon cancer in the UK. PMID:16622438

  4. lncRNA HOTAIR Contributes to 5FU Resistance through Suppressing miR-218 and Activating NF-κB/TS Signaling in Colorectal Cancer

    Directory of Open Access Journals (Sweden)

    Peilong Li

    2017-09-01

    Full Text Available One major reason for the failure of advanced colorectal cancer (CRC treatment is the occurrence of chemoresistance to fluoropyrimidine (FU-based chemotherapy. Long non-coding RNA HOTAIR has been considered as a pro-oncogene in multiple cancers. However, the precise functional mechanism of HOTAIR in chemoresistance is not well known. In this study, we investigated the biological and clinical role of HOTAIR in 5FU resistance in CRC. Our results showed that HOTAIR negatively regulated miR-218 expression in CRC through an EZH2-targeting miR-218-2 promoter regulatory axis. HOTAIR knockdown dramatically inhibited cell viability and induced G1-phase arrest by promoting miR-218 expression. VOPP1 was shown to be a functional target of miR-218, and the main downstream signaling, NF-κB, was inactivated by HOTAIR through the suppression of miR-218 expression. Additionally, HOTAIR knockdown partially reversed 5FU resistance through promoting miR-218 and inactivating NF-κB signaling. Furthermore, HOTAIR restrained 5FU-induced cytotoxicity on CRC cells through promotion of thymidylate synthase expression. More importantly, high HOTAIR expression was associated with poor response to 5FU treatment. In conclusion, we demonstrated that HOTAIR contributes to 5FU resistance through suppressing miR-218 and activating NF-κB signaling in CRC. Thus, HOTAIR may serve as a promising therapeutic target for CRC patients.

  5. Special issue dedicated to Professor Johann M. Schepers

    Directory of Open Access Journals (Sweden)

    Gideon P De Bruin

    2006-04-01

    Full Text Available It is a great pleasure for me to have been associated with this special issue of the SA Journal of Industrial Psychology dedicated to Professor Johann M. Schepers. The purpose of the special issue is to honour Professor Schepers for his contributions to the development of Psychology and Industrial Psychology as empirical fields of study in South Africa. The contributors have worked with Professor Schepers as students or colleagues and share his academic interests. The articles reflect his areas of interest and employ analytic techniques taught and championed by him. We are grateful to Professor Schepers for his cooperation throughout this project. Thanks are due to all the contributors and referees.

  6. Three professors honored by Virginia Veterinary Medical Association

    OpenAIRE

    Douglas, Jeffrey S.

    2005-01-01

    The Virginia Veterinary Medical Association (VVMA) recently honored three professors from the Virginia-Maryland Regional College of Veterinary Medicine (VMRCVM) during its annual meeting at the Hotel Roanoke.

  7. The Effect of Professor's Attractiveness On Distance Learning Students

    Directory of Open Access Journals (Sweden)

    Jeanny Liu

    2015-07-01

    Full Text Available Technology enabled learning is becoming more popular and pervasive in education. While the effectiveness of distance learning versus traditional classroom education is strongly debated, human factors such as students’ perception of their professors can influence their desire to learn. This research examines the perceptual effect of attractive professors on business students enrolled in distance learning courses. This study expands on prior studies by testing whether the attractiveness of the professor matters to student learning within the context of online learning environment. A total of 122 online business students were surveyed. Our findings suggest that professor’s attractiveness has a statistically significant effect on student learning, motivation, and satisfaction. In addition, online students perceived attractive professors with more expertise as an instructor. Female students had higher motivation than male students. Furthermore, separate analysis indicated that attractiveness effects were stronger for participants over the age 46 when compared to other groups.

  8. Professor Nambu, string theory, and the moonshine phenomenon

    OpenAIRE

    Eguchi, Tohru

    2016-01-01

    I first recall the last occasion I met the late Professor Yoichiro Nambu, in a hospital in Osaka. I then present a brief introduction to a moonshine phenomenon in string theory that have recently come under investigation.

  9. DA Professor Honored for Teaching Excellence With Annual Hamming Award

    OpenAIRE

    Chagoya, Javier

    2017-01-01

    NPS Department of Defense Analysis Associate Professor Heather Gregg is the recipient of the 2017 Richard W. Hamming Annual Faculty Award for Achievement in Teaching, recognizing her exceptional work ... Read More

  10. INTRODUCTION: A TRIBUTE TO PROFESSOR MARJORIE L. GIRTH

    National Research Council Canada - National Science Library

    Armstead C Lewis

    2015-01-01

    ..., professional responsibility, and women's rights. Professor Girth joined the Buffalo Law School faculty in 1971 where she chaired the New York State Bar Association's Banking, Corporation and Business Law Section and was a member of the American Bar...

  11. Interview: Professor Andrew Feinberg speaks to Epigenomics.

    Science.gov (United States)

    Feinberg, Andrew

    2009-10-01

    Andrew Feinberg studied mathematics and humanities at Yale University (CT, USA) in the Directed Studies honors program, and he received his BA (1973) and MD (1976) from the accelerated medical program at Johns Hopkins University (MD, USA), as well as an MPH from Johns Hopkins (1981). He performed a postdoctoral fellowship in developmental biology at the University of California, San Diego (UCSD, CA, USA), clinical training in medicine and medical genetics at the University of Pennsylvania (PA, USA) and genetics research with Bert Vogelstein at Johns Hopkins, discovering altered DNA methylation in human cancer. Dr Feinberg continued to perform seminal work in cancer epigenetics as a Howard Hughes investigator at the University of Michigan (MI, USA), discovering human imprinted genes and loss of imprinting in cancer, and the molecular basis of Beckwith-Wiedemann syndrome. He returned to John Hopkins in 1994 as King Fahd Professor of Medicine, Molecular Biology & Genetics and Oncology, and he holds an Adjunct Professorship at the Karolinska Institute in Sweden. Dr Feinberg is Director of the Center for Epigenetics, a National Human Genome Research Institute-designated Center of Excellence in Genome Sciences. The Center is pioneering genome-scale tools in molecular, statistical and epidemiological epigenetics, and is applying them to the study of cancer, neuropsychiatric disease and aging. As part of the center, Dr Feinberg has organized a highly innovative program to bring gifted minority high-school students into genetics and genomics. Dr Feinberg has also invented a number of widely used molecular tools, including random priming. His honors include election to the American Society for Clinical Investigation, the Association of American Physicians, the Institute of Medicine of the National Academy of Sciences, and the American Academy of Arts and Sciences, as well as membership on the ISI most-cited authors list, a MERIT Award of the National Cancer Institute, a

  12. University Pedagogy for Assistant Professors at Aalborg University (Part 1)

    DEFF Research Database (Denmark)

    Kolmos, Anette; Krogh, Lone

    2003-01-01

    The article describes a course for assistant professors within the University Teacher Education at Aalborg University. The course focus is to develop knowledge, skills and methods from within the didactic, pedagogical, and learning theory-based fields.......The article describes a course for assistant professors within the University Teacher Education at Aalborg University. The course focus is to develop knowledge, skills and methods from within the didactic, pedagogical, and learning theory-based fields....

  13. Sex and Science: How Professor Gender Perpetuates the Gender Gap

    OpenAIRE

    Scott E. Carrell; Marianne E. Page; West, James E.

    2009-01-01

    Why aren't there more women in science? Female college students are currently 37 percent less likely than males to obtain a bachelor's degree in science, technology, engineering, and math (STEM), and comprise only 25 percent of the STEM workforce. This paper begins to shed light on this issue by exploiting a unique dataset of college students who have been randomly assigned to professors over a wide variety of mandatory standardized courses. We focus on the role of professor gender. Our resul...

  14. Emotional exhaustion and burnout among medical professors; a nationwide survey

    OpenAIRE

    Joeri K Tijdink; Vergouwen, Anton CM; Yvo M Smulders

    2014-01-01

    Background Although job-related burnout and its core feature emotional exhaustion are common among medical professionals and compromise job satisfaction and professional performance, they have never been systematically studied in medical professors, who have central positions in academic medicine. Methods We performed an online nationwide survey inviting all 1206 medical professors in The Netherlands to participate. They were asked to fill out the Maslach Burnout Inventory, a ‘professional en...

  15. The Effect of Professor's Attractiveness On Distance Learning Students

    OpenAIRE

    Jeanny Liu; Stella D. Tomasi

    2015-01-01

    Technology enabled learning is becoming more popular and pervasive in education. While the effectiveness of distance learning versus traditional classroom education is strongly debated, human factors such as students’ perception of their professors can influence their desire to learn. This research examines the perceptual effect of attractive professors on business students enrolled in distance learning courses. This study expands on prior studies by testing whether the attractiveness of the ...

  16. The compound Chinese medicine "Kang Fu Ling" protects against high power microwave-induced myocardial injury.

    Directory of Open Access Journals (Sweden)

    Xueyan Zhang

    Full Text Available BACKGROUND: The prevention and treatment of Microwave-caused cardiovascular injury remains elusive. This study investigated the cardiovascular protective effects of compound Chinese medicine "Kang Fu Ling" (KFL against high power microwave (HPM-induced myocardial injury and the role of the mitochondrial permeability transition pore (mPTP opening in KFL protection. METHODS: Male Wistar rats (100 were divided into 5 equal groups: no treatment, radiation only, or radiation followed by treatment with KFL at 0.75, 1.5, or 3 g/kg/day. Electrocardiography was used to Electrophysiological examination. Histological and ultrastructural changes in heart tissue and isolated mitochondria were observed by light microscope and electron microscopy. mPTP opening and mitochondrial membrane potential were detected by confocal laser scanning microscopy and fluorescence analysis. Connexin-43 (Cx-43 and endothelial nitric oxide synthase (eNOS were detected by immunohistochemistry. The expression of voltage-dependent anion channel (VDAC was detected by western blotting. RESULTS: At 7 days after radiation, rats without KFL treatment showed a significantly lower heart rate (P<0.01 than untreated controls and a J point shift. Myocyte swelling and rearrangement were evident. Mitochondria exhibited rupture, and decreased fluorescence intensity, suggesting opening of mPTP and a consequent reduction in mitochondrial membrane potential. After treatment with 1.5 g/kg/day KFL for 7 d, the heart rate increased significantly (P<0.01, and the J point shift was reduced flavorfully (P<0.05 compared to untreated, irradiated rats; myocytes and mitochondria were of normal morphology. The fluorescence intensities of dye-treated mitochondria were also increased, suggesting inhibition of mPTP opening and preservation of the mitochondrial membrane potential. The microwave-induced decrease of Cx-43 and VDAC protein expression was significantly reversed. CONCLUSION: Microwave radiation can

  17. Exemplary Chinese University Professors: Qualities and Impact on Students

    Directory of Open Access Journals (Sweden)

    Eugene P. Kim

    2016-03-01

    Full Text Available This study focuses on the qualities of Chinese university professors as perceived by their students and the effects of those qualities on student learning and motivation. Specifically, what qualities and personal characteristics do Chinese university students attribute to their favorite and least favorite professors, and how do those qualities and characteristics affect Chinese university students? Out of 280 students surveyed from three different universities, 226 surveys were completed, returned and included in the final analysis (response rate of 80.7%. The research found that Chinese students favored professors who are entertaining, who help them learn more and who provide them with helpful feedback on their assignments. Students disfavor professors who are boring, arrogant and do not provide helpful feedback or help them learn more. Linear regressions revealed a connection between high quality professors and student learning and motivation. Along with other studies, this research provides evidence that effective university professors are those who not only possess expertise in their fields, but in addition are engaging, student-focused and able to build rapport with their students.

  18. A randomized phase III multicenter trial comparing irinotecan in combination with the Nordic bolus 5-FU and folinic acid schedule or the bolus/infused de Gramont schedule (Lv5FU2) in patients with metastatic colorectal cancer

    DEFF Research Database (Denmark)

    Glimelius, B; Sørbye, H; Balteskard, L

    2008-01-01

    not differ (4% versus 6%, P = 0.3). Grade 3/4 neutropenia (11% versus 5%, P = 0.01) and grade 2 alopecia (18% versus 9%, P = 0.002) were more common in the FLIRI group. The 60-day mortality was 2.4% versus 2.1%. CONCLUSIONS: Irinotecan with the bolus Nordic schedule (FLIRI) is a convenient treatment with PFS...... and OS comparable to irinotecan with the Lv5FU2 schedule. Neutropenia and alopecia are more prevalent, but both regimens are equally well tolerated....

  19. Even great ideas have limits - examining the Turc-Mezentsev and the Tixeront-Fu water balance formulas

    Science.gov (United States)

    Andréassian, Vazken; de Lavenne, Alban

    2017-04-01

    A variety of models and formulas exist to represent the precipitation-flow transformation. In the recent years, simple formulas describing the long-term hydrological balance have received a lot of interest; the most widely discussed being the Turc-Mezentsev (Turc, 1954; Mezentsev, 1955) and the Tixeront-Fu (Tixeront, 1964; Fu, 1981) formulas. Although we largely share the enthusiasm of our colleagues concerning these two formulas, we would like to examine here their limits concerning an important aspect: their inability to reproduce the observed elasticity of streamflow to precipitation and potential evaporation (Andréassian et al., 2016; Berghuijs & Woods, 2016). We discuss whether this could be due to the fact that they do not account for the seasonality, timing and intensity of precipitation, and propose simple ways to include these factors in the original formulations. References Andréassian, V., L. Coron, J. Lerat, and N. Le Moine. 2016. Climate elasticity of streamflow revisited - an elasticity index based on long-term hydrometeorological records. Hydrology and Earth System Sciences, 20, 4503-4524. Berghuijs, W. R. & Woods, R. A., 2016. Space-time asymmetry undermines water yield assessment. Nat. Commun. 7:11603. Fu, B., 1981. On the calculation of the evaporation from land surface (in Chinese). Atmospherica Sinica, 5: 23-31. Mezentsev, V., 1955. Back to the computation of total evaporation (in Russian). Meteorologia i Gidrologia, 5: 24-26. Tixeront, J., 1964. Prediction of streamflow (in French), IAHS publication n°63: General Assembly of Berkeley. IAHS, Gentbrugge, pp. 118-126. Turc, L., 1954. The water balance of soils: relationship between precipitations, evaporation and flow (in French). Annales Agronomiques, Série A(5): 491-595.

  20. Multiwavelength Observations of V2775 Ori, an Outbursting Protostar in L 1641: Exploring the Edge of the FU Orionis Regime

    Science.gov (United States)

    Fischer, William J.; Megeath, S. Thomas; Tobin, John J.; Stutz, Amelia M.; Ali, Babar; Remming, Ian; Kounkel, Marina; Stanke, Thomas; Osorio, Mayra; Henning, Thomas; Manoj, P.; Wilson, T. L.

    2012-09-01

    Individual outbursting young stars are important laboratories for studying the physics of episodic accretion and the extent to which this phenomenon can explain the luminosity distribution of protostars. We present new and archival data for V2775 Ori (HOPS 223), a protostar in the L 1641 region of the Orion molecular clouds that was discovered by Caratti o Garatti et al. to have recently undergone an order-of-magnitude increase in luminosity. Our near-infrared spectra of the source have strong blueshifted He I λ10830 absorption, strong H2O and CO absorption, and no H I emission, all typical of FU Orionis sources. With data from the Infrared Telescope Facility, the Two Micron All Sky Survey, the Hubble Space Telescope, Spitzer, the Wide-field Infrared Survey Explorer, Herschel, and the Atacama Pathfinder Experiment that span from 1 to 70 μm pre-outburst and from 1 to 870 μm post-outburst, we estimate that the outburst began between 2005 April and 2007 March. We also model the pre- and post-outburst spectral energy distributions of the source, finding it to be in the late stages of accreting its envelope with a disk-to-star accretion rate that increased from ~2 × 10-6 M ⊙ yr-1 to ~10-5 M ⊙ yr-1 during the outburst. The post-outburst luminosity at the epoch of the FU Orionis-like near-IR spectra is 28 L ⊙, making V2775 Ori the least luminous documented FU Orionis outburster with a protostellar envelope. The existence of low-luminosity outbursts supports the notion that a range of episiodic accretion phenomena can partially explain the observed spread in protostellar luminosities.

  1. Forecasting the Student-Professor Matches That Result in Unusually Effective Teaching

    Science.gov (United States)

    Gross, Jennifer; Lakey, Brian; Lucas, Jessica L.; LaCross, Ryan; Plotkowski, Andrea R.; Winegard, Bo

    2015-01-01

    Background: Two important influences on students' evaluations of teaching are relationship and professor effects. Relationship effects reflect unique matches between students and professors such that some professors are unusually effective for some students, but not for others. Professor effects reflect inter-rater agreement that some professors…

  2. [Syndrome of inappropriate antidiuretic hormone secretion following adjuvant CDDP and 5-FU administration in a patient with esophageal carcinoma].

    Science.gov (United States)

    Horio, Takuya; Tsujimoto, Hironori; Akase, Takayoshi; Sakamoto, Naoko; Yaguchi, Yoshihisa; Hiraki, Shuuichi; Aiko, Satoshi; Takechi, Hanako; Hase, Kazuo; Maehara, Tadaaki

    2010-10-01

    A case of hyponatremia following the first course of systemic adjuvant chemotherapy with cisplatin (CDDP) and 5-FU in a previously treated patient with esophageal cancer is reported. A 61-year-old man was admitted to our hospital for adjuvant chemotherapy after transthoracic esophagectomy and 3-field lymphadenectomy for esophageal cancer. Six days following chemotherapy, his serum sodium concentration was found to be 118 mEq/L, without edema or dehydration. This hyponatremic state was diagnosed as the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) induced by CDDP, based on the hypo-osmolality of his serum and urine, and an inappropriate level of plasma vasopressin.

  3. Dedication to Professor Hannspeter Winter (1941 2006): Dedication to Professor Hannspeter Winter (1941 2006)

    Science.gov (United States)

    McCullough, Bob

    2007-03-01

    Professor H Winter. It was with great sadness that we learnt of the death of colleague and friend Professor Hannspeter Winter in Vienna on the 8 November 2006. In memory of him and the contribution he made both to our conference and to the field of the physics of highly charged ions we dedicate these proceedings. Hannspeter was one of our distinguished invited speakers at HCI2006 and gave a talk on the status of the ITER programme. His invited paper on the subject is included in these proceedings. Hannspeter will be particularly remembered for his pioneering work on ion-surface interactions that, together with his colleagues at the Vienna University of Technology (TUW), has stimulated a worldwide experimental and theoretical interest in this field. He was appointed Director of the Institut fuer Allgemeine Physik at TUW in 1987 and using both his scientific and management skills has made it one of the leading university physics laboratories in the world. His research publications, of which there are 270, have inspired many others to work in the field of atomic and plasma physics. He was also a great European playing a major role in the EURATOM fusion programme, the European Physical Society and the International Union of Pure and Applied Physics and was an evaluator and advisory board member for many national and international institutions. Hannspeter was also an interesting and friendly social companion with interests in current affairs, music and fine wines and will be greatly missed both on a scientific and social level. Our condolences go to his wife Renate, son Dorian and his relatives. R W McCullough Co-chair HCI2006

  4. A novel comprehensive set of fungal Real time PCR assays (fuPCR) for the detection of fungi in immunocompromised haematological patients-A pilot study.

    Science.gov (United States)

    Rahn, Sebastian; Schuck, Anna; Kondakci, Mustafa; Haas, Rainer; Neuhausen, Nicole; Pfeffer, Klaus; Henrich, Birgit

    2016-12-01

    Fungal infections are recognized in an increasing number of patients with immunological deficits and are associated with high rates of mortality (Brown et al., 2012a). In this pilot-study, a rapid Real time PCR (fuPCR) was designed for the detection and differentiation of fungal pathogens in clinical specimens of haematological patients. The fuPCR, targeting the internal transcribed spacer region 2 (ITS2) of rDNA region, is comprised of seven multiplex reactions, which were shown to be specific and sensitive for a comprehensive spectrum of clinically relevant fungal species. This was validated by testing respective fungal DNAs in each fuPCR reaction and 28 respiratory samples of fungal pneumonia-proven patients. Clinical sample sets of throat swab, EDTA-blood and blood sera from 50 patients with severe haematological malignancies, including haematopoietic stem cell transfer (HSCT), and samples from 30 healthy individuals were then analysed. In a first step, 198 samples of immunosuppressed patients were solely examined by fuPCR; and 50.8% (33/65) respiratory swabs, 4.8% (3/63) EDTA blood samples and 1.4% (1/70) blood serum samples were tested positive. In a second step, 56 respiratory samples of immunosuppressed patients and 30 of healthy individuals were simultaneously analysed by fuPCR and standard cultivation techniques. By both methods 30.4% (17/56) swabs of the immunocompromised patients were tested positive, 37.5% (21/56) were tested negative and 32.1% (18/56) were tested fuPCR positive and culture negative. In analysing the blood samples of the immunocompromised patients 5.4% (3/56) EDTA blood samples and 16.1% (9/56) sera samples were tested fuPCR-positive, whereas all samples of 30 healthy individuals with no signs of immunological deficits were tested negative by fuPCR. 38.9% (14/36) of the fungi detected in respiratory samples of the immunosuppressed patients, belonged to Candida spp., 47.2% (17/36) to Saccharomyces spp., 5.6% (2/36) to Cladosporium spp

  5. Progress on Scaling the Sheared-Flow Stabilized Z-Pinch: The Fusion Z-Pinch Experiment ``FuZE''

    Science.gov (United States)

    Nelson, B. A.; Shumlak, U.; Claveau, E. L.; Forbes, E. G.; Golingo, R. P.; Stepanov, A. D.; Weber, T. R.; Zhang, Y.; McLean, H. S.; Higginson, D. P.; Schmidt, A. E.; Tummel, K. K.

    2017-10-01

    The sheared-flow-stabilized (SFS) Z-pinch ZaP experiment was constructed based on calculations showing stabilization of the kink and sausage instabilities with sufficient flow shear. ZaP experimentally demonstrated production and sustainment of an SFS Z-pinch for a wide range of plasma parameters, with densities up to n = 5 ×1022 m-3 and a pinch radius of a=1 cm. The follow-on ZaP-HD (high density) experiment demonstrated scaling of the SFS Z-pinch to 2-3x smaller radii and 10x higher densities than ZaP, with up to 1 keV temperatures. Based on the successful results of ZaP and ZaP-HD, the Fusion Z-pinch Experiment (FuZE) project is experimentally and computationally studying scaling the plasma performance toward fusion conditions, with the target of a smaller radius, a=1 mm, and higher density, n = 2 ×1024 m-3. Initial FuZE experimental results show several hundred eV ion temperatures, with pinch currents of 100-200 kA and a few mm radius. 2D kinetic calculations show stabilization of instabilities at moderate sheared flows, and 3D kinetic calculations are in progress. This work is supported by an award from US ARPA-E.

  6. Estimation of Asian Dust Aerosol Effect on Cloud Radiation Forcing Using Fu-Liou Radiative Model and CERES Measurements

    Science.gov (United States)

    Su, Jing; Huang, Jianping; Fu, Qiang; Minnis, Patrick; Ge, Jinming; Bi, Jianrong

    2008-01-01

    The impact of Asian dust on cloud radiative forcing during 2003-2006 is studied by using the Earth's Radiant Energy Budget Scanner (CERES) data and the Fu-Liou radiative transfer model. Analysis of satellite data shows that the dust aerosol significantly reduced the cloud cooling effect at TOA. In dust contaminated cloudy regions, the 4-year mean values of the instantaneous shortwave, longwave and net cloud radiative forcing are -138.9, 69.1, and -69.7 Wm(sup -2), which are 57.0, 74.2, and 46.3%, respectively, of the corresponding values in more pristine cloudy regions. The satellite-retrieved cloud properties are significantly different in the dusty regions and can influence the radiative forcing indirectly. The contributions to the cloud radiation forcing by the dust direct, indirect and semi-direct effects are estimated using combined satellite observations and Fu-Liou model simulation. The 4-year mean value of combination of indirect and semi-direct shortwave radiative forcing (SWRF) is 82.2 Wm(sup -2), which is 78.4% of the total dust effect. The direct effect is only 22.7 Wm(sup -2), which is 21.6% of the total effect. Because both first and second indirect effects enhance cloud cooling, the aerosol-induced cloud warming is mainly the result of the semi-direct effect of dust.

  7. Professor-psicopedagogo: o que este profissional faz na escola

    Directory of Open Access Journals (Sweden)

    Caroline Andrea Pottker

    Full Text Available Este estudo teve como objetivo identificar o porquê da presença do professor-psicopedagogo nas escolas e qual a função que este desempenha dentro delas, bem como, suas implicações no processo ensino-aprendizagem. Para tanto, foram entrevistados dez professores-psicopedagogos, pertencentes a cinco escolas localizadas no Estado do Paraná. Os resultados apontaram que o cargo de professor-psicopedagogo foi ocupado por professores que tinham o título de especialista em Psicopedagogia, os quais passaram a realizar avaliações psicopedagógicas dos alunos com dificuldades de aprendizagem. Segundo a maioria desses profissionais, uma de suas funções constitui-se em auxiliar o professor que apresenta em sala de aula alunos com dificuldades de aprendizagem, assim como tentar compreender o porquê de estes alunos não estarem aprendendo, sobretudo, ajudá-los na reversão desta problemática. Concluímos que a atuação deste profissional nestas escolas pouco tem contribuído para resolução das dificuldades de aprendizagem, pois centram-se no indivíduo e não no processo ensino-aprendizagem.

  8. [Clinical study of serum and tissue concentrations of FT-207 and 5-FU in patients with cancer of the large intestine following preoperative application of FT-207 suppositories].

    Science.gov (United States)

    Okuda, M; Teramoto, T; Yoshida, H; Sato, K; Ushijima, Y; Uematsu, Y

    1982-09-01

    1.5 g/day of FT-207 suppository was administered for two weeks prior to operation to twenty patients with large bowel carcinoma of familiar poliposis coli. The level of FT-207 and 5-FU in serum, lymph node, tumor and normal colonic mucosa were determined by bioassay. The levels of FT-207 in the rectum, sigmoid colon and tumor were higher than that in serum. The levels of 5-FU in the rectum, sigmoid colon, tumor and lymph node were also higher than that in serum. The levels of FT-207 and 5-FU in carcinoma of the rectum was higher than those in serum. Compared with the level in normal rectal mucosa, only the level of 5-FU in rectal carcinoma was higher. From the histological point of view, the highest levels of FT-207 and 5-FU was observed in well-differentiated adenocarcinoma. There was no side effect experienced in our series, therefore, FT-207 suppository seems to be one of the safe promising preoperative chemotherapies.

  9. PROFESSOR DR. ION PIŞOTA (1925 – 2008

    Directory of Open Access Journals (Sweden)

    Liliana ZAHARIA

    2009-12-01

    Full Text Available Professor Ion Pişota was born on June 6, 1925, in Hrupiştea, a small settlement in Greek Macedonia, from where he and his family came to Romania in 1927, where he got Romanian citizenship. Between 1941 and 1945, he attended the Tulcea Boys High School and later on, in 1947 he entered the Faculty of Geology – Geography at the University of Bucharest, where he continued to excel until 1951, when he graduated. In the fall of 1950, he took up a tutor position in the field of Hydrolgy at the same faculty passing subsequently through all the stages of academic hierarchy until he became, in 1971, a University Professor. Even after he retired, in 1996, he continued his academic activity as a consultant professor within the same department and faculty that he served with passion and devotion for more than 50 years.

  10. Categorization of Quantum Mechanics Problems by Professors and Students

    CERN Document Server

    Lin, Shih-Yin

    2016-01-01

    We discuss the categorization of 20 quantum mechanics problems by physics professors and undergraduate students from two honors-level quantum mechanics courses. Professors and students were asked to categorize the problems based upon similarity of solution. We also had individual discussions with professors who categorized the problems. Faculty members' categorizations were overall rated higher than those of students by three faculty members who evaluated all of the categorizations. The categories created by faculty members were more diverse compared to the categories they created for a set of introductory mechanics problems. Some faculty members noted that the categorization of introductory physics problems often involves identifying fundamental principles relevant for the problem, whereas in upper-level undergraduate quantum mechanics problems, it mainly involves identifying concepts and procedures required to solve the problem. Moreover, physics faculty members who evaluated others' categorizations express...

  11. Faculty Agency in Applying for Promotion to Professor

    Directory of Open Access Journals (Sweden)

    Susan K. Gardner

    2017-02-01

    Full Text Available Aim/Purpose: In the United States, faculty who wish to pursue promotion to the rank of professor do so without clear guidance or structure. Even the timing of such a process is nebulous. As such, an individual engages in agentic action to pursue the rank. Background: This study examined the experiences of faculty members who chose to pursue the application process to be promoted to professor but were rejected or dissuaded. Methodology: Utilizing a case study of one institutional setting, we conducted 10 in-depth qualitative interviews. Contribution: Very little is known about the process of promotion to full professor in the U.S. and even less empirical research exists. This study advances knowledge of the process and the experiences of those undertaking it. Findings: We learned that cues from the social context greatly influenced these faculty members’ sense of agency.

  12. [Professor Frantisek Por MD and Professor Robert Klopstock MD, students at Budapest and Prague Faculties of Medicine].

    Science.gov (United States)

    Mydlík, M; Derzsiová, K

    2010-11-01

    Professor Frantisek Por MD and Professor Robert Klopstock MD were contemporaries, both born in 1899, one in Zvolen, the other in Dombovar, at the time of Austro-Hungarian Monarchy. Prof. Por attended the Faculty of Medicine in Budapest from 1918 to 1920, and Prof. Klopstock studied at the same place between 1917 and 1919. From 1920 until graduation on 6th February 1926, Prof. Por continued his studies at the German Faculty of Medicine, Charles University in Prague. Prof. Klopstock had to interrupt his studies in Budapest due to pulmonary tuberculosis; he received treatment at Tatranske Matliare where he befriended Franz Kafka. Later, upon Kafka's encouragement, he changed institutions and continued his studies at the German Faculty of Medicine, Charles University in Prague, where he graduated the first great go. It is very likely that, during their studies in Budapest and Prague, both professors met repeatedly, even though their life paths later separated. Following his graduation, Prof. Por practiced as an internist in Prague, later in Slovakia, and from 1945 in Kosice. In 1961, he was awarded the title of university professor of internal medicine at the Faculty of Medicine, Pavol Jozef Safarik University in Kosice, where he practiced until his death in 1980. Prof. Klopstock continued his studies in Kiel and Berlin. After his graduation in 1933, he practiced in Berlin as a surgeon and in 1938 left for USA. In 1962, he was awarded the title of university professor of pulmonary surgery in NewYork, where he died in 1972.

  13. Clinical study of the combination of small amount of nedaplatin (CDGP)/5-FU with radiation for the treatment of esophageal cancer

    Energy Technology Data Exchange (ETDEWEB)

    Inaba, Hiroyuki; Tsuda, Takashi; Miyazaki, Aya [St. Marianna Univ., Kawasaki, Kanagawa (Japan). School of Medicine] (and others)

    2002-10-01

    Recently chemoradiotherapy for esophageal cancer has been drawing public attention to the issue of quality of life maintenance for patients. Although the standard method of chemoradiotherapy is CDDP/5FU, it has been claimed that CDGP (a derivative of CDDP) alone is more effective than CDDP for the treatment of esophageal cancer due to its low nephro- and digestive toxicity. We used a small amount of CDGP/5-FU in combination with radiation instead of CDDP, for the treatment of esophageal cancer and performed clinical examination of patients. The partial response rate was 80% and the complete response rate was 50%. Major side-effects were leukopenia, neutropenia, thrombocytopenia and anemia. Further study of dosage and schedule is necessary, however, CDGP/5-FU combined with radiation therapy could be used as choices of chemoradiotherapy for esophageal cancer in the future. (author)

  14. Análisis y determinación de parámetros físicos de estrellas de tipo FU Orionis

    Science.gov (United States)

    Gramajo, L.; Gómez, M.; Whitney, B.

    FU Orionis stars (FUORs) are pre-main sequence objects that periodically incur in a steeply increase of brightness (outburst) of DeltaV~ 6 mag in a period of ~ 10 yr, followed by a gradual descent to the original magnitude in an interval of time of ~100 yr. In this contribution we present initial results on the modeling of the spectral energy distributions (SEDs) of a group of 7 FU Orionis stars: FU Ori, V1515 Cyg, V1057 Cyg, Z CMa, BBW 76, V1735 Cyg, and V883 Ori. We initially used the grid of SEDs calculated by Robitaille et al. (2006). This solution was refined applying the code developed by Whitney et al. (2003). We derived physical and geometrical parameters for the disks of these FUORs. We compared these properties with those of ''canonical'' T Tauri disks. FULL TEXT IN SPANISH

  15. [Successful treatment of a patient with recurrent ovarian clear cell adenocarcinoma under combination chemotherapy of 5-FU (civ) and low-dose CDDP (i.v.)].

    Science.gov (United States)

    Sakaihara, M; Sakai, K; Hara, Y; Kataoka, S; Tabata, M; Hanatani, K; Hareyama, H

    2000-01-01

    Resistance to conventional chemotherapy including CDDP is the most important therapeutic problem in ovarian cancer. The combination chemotherapy of 5-FU (civ) and low-dose CDDP (i.v.) was applied to a patient with recurrent ovarian clear cell adenocarcinoma (stage IIa), which is often more resistant to systemic chemotherapy than other ovarian adenocarcinomas and is a poor prognostic factor. The patient underwent cytoreductive surgery. Then, 5-FU 375 mg/m2/day civ (days 1-5, 8-12, 15-19, 22-26) and CDDP 3.75 mg/m2/day i.v. (days 1-5, 8-12, 15-19, 22-26) were administered. After four courses of this treatment, there is no sign of recurrence. This result indicates that the combination of 5-FU and CDDP is useful in the treatment of recurrent ovarian cancers.

  16. Aspectos gerais da formação de professores

    Directory of Open Access Journals (Sweden)

    Edson do Carmo Inforsato

    1996-08-01

    Full Text Available Este artigo, ancorado em estudos recentes e antigos, mostra o afastamento dos cursos de formação de professores em relação aos elementos que compõem a prática profissional docente. Favorável a uma aproximação efetiva com o contexto das práticas de sala de aula, o autor defende a idéia de uma formação de professores atrelada aos problemas e necessidades da prática docente no ensino formal de 1º e 2º graus.

  17. O papel do formador no processo reflexivo de professores

    OpenAIRE

    Altarugio Helena, M.

    2009-01-01

    Este trabalho pretende discutir as práticas e os discursos de uma formadora de professores de ciências, experiente e bem sucedida na formação inicial e continuada. Nossa hipótese é a de que, além dos conhecimentos e das técnicas, é na relação intersubjetiva construída entre a formadora e o grupo de professores, que se encontram os elementos que irão sustentar o processo de formação docente. A partir do modo singular da formadora de enfrentar sua tarefa educativa e lidar com as dificuldades do...

  18. Preditores da Síndrome de Burnout em professores

    Directory of Open Access Journals (Sweden)

    Mary Sandra Carlotto

    Full Text Available O objetivo deste estudo foi identificar os preditores da Síndrome de Burnout em 563 professores de instituições educacionais particulares da região metropolitana de Porto Alegre - RS. Foram utilizados um questionário elaborado para levantamento de variáveis demográficas e profissionais, o Maslach Burnout Inventory, o Job Diagnostic Survey e o Questionário de Satisfação no Trabalho S20/23. Os resultados evidenciam que variáveis relacionadas ao contexto laboral predominam no modelo explicativo de Burnout em professores em ambos os grupos.

  19. Apoio social e fatores associados com a disfonia em professores

    OpenAIRE

    Ceballos,Albanita Gomes da Costa de

    2009-01-01

    p. 1-68 Fatores relacionados com o ambiente e a organização do trabalho, além de fatores próprios do sujeito têm se mostrado associados ao adoecimento vocal de professores. O objetivo deste estudo foi analisar os fatores associados a disfonia nesta categoria profissional e investigar a contribuição do apoio social no processo de adoecimento vocal de professores. Foram pesquisados 476 docentes de escolas municipais de quatro regionais de educação da cidade de Salvador – Bahia. A coleta de d...

  20. Women Professors of Educational Administration: A Profile and Salient Issues.

    Science.gov (United States)

    Short, Paula M.; And Others

    The purpose of this study is to assess the current status of women professors of educational administration. Research findings are reviewed and discussed in the areas of socialization of women and sex-role stereotyping, mentoring, and networking. A 37-item questionnaire addressed background information, graduate school experiences, first…

  1. [Professor TIAN Cong-huo's experience on clinical acupuncture].

    Science.gov (United States)

    Song, Shi-Yun; Wang, Yin

    2008-10-01

    Professor TIAN's experiences on acupuncture treatment of various difficult diseases with different acupuncture methods based on syndrome differentiation of different patients, for example, para-acupuncture for treatment of migraine, triple puncture at Dazhui (GV 14) for recurrent depression, lifting and thrusting point Shexiaxue for treatment of aphasia, electroacupuncture at Shuigou (GV 26) and Baihui (GV 20) for treatment of schizophrenia, etc. are introduced.

  2. Häbi, professor, teil on Gefilus kapis / Eve Kruuse

    Index Scriptorium Estoniae

    Kruuse, Eve,d1959-

    2008-01-01

    Tartu Ülikooli professor Marika Mikelsaar võitis läinud kuul koos kolleegidega (Tiiu Kullisaar, Epp Songisepp, Hedi Annuk ja Mihkel Zilmer) Soulis ülemaailmse naisleiutajate konkursil ME-3 bakteri avastamise ja probiootikuks arendamise eest kuldmedali

  3. Burnout Syndrome and Self-Efficacy Beliefs in Professors

    Science.gov (United States)

    García Padilla, Arlington Antonio; Escorcia Bonivento, Carla Vanessa; Perez Suarez, Blinis Sat

    The presence of the Burnout syndrome in professors may be regarded as a deterioration of their mental health with negative impacts on their job performance. It is known that teachers develop different activities in the areas of teaching, outreach and research. This study aims to analyze the relationship between the Burnout syndrome and…

  4. Communication professor examines media bias in president's speeches

    OpenAIRE

    Elliott, Jean

    2006-01-01

    Jim A. Kuypers, assistant professor of communication in the College of Liberal Arts and Human Sciences at Virginia Tech, reveals a disturbing world of media bias in his new book Bush's War: Media Bias and Justifications for War in a Terrorist Age (Rowman & Littlefield Publishers, Inc. 2006).

  5. A Comparison of Students' Perceptions of an Ideal Professor.

    Science.gov (United States)

    Gadzella, Bernadette M.; And Others

    A study was done of college students' current perceptions of the most and least important characteristics of an ideal professor. These perceptions were compared with findings from earlier studies, and differences among student groups (based on gender, college status, grade point average (GPA), and majors) were compared. The study surveyed 356…

  6. Analysis of an Instrument on a Quality Professor.

    Science.gov (United States)

    Lytton, Channon R.; Gadzella, Bernadette M.

    The reliability of the questionnaire, Students' Views of an Ideal Professor, was studied. Subjects were 86 students (35 males and 51 females) who were enrolled in psychology classes at a state university. Subjects included 34 freshmen, 27 sophomores, 20 juniors, 4 seniors, and 1 graduate. The questionnaire consists of 25 characteristics of a…

  7. University Professors and Teaching Ethics: Conceptualizations and Expectations

    Science.gov (United States)

    Dean, Kathy Lund; Beggs, Jeri Mullins

    2006-01-01

    After the spectacular ethical breaches in corporate America emerged, business school professors were singled out as having been negligent in teaching ethical standards. This exploratory study asked business school faculty about teaching ethics, including conceptualizations of ethics in a teaching context and opinions of the extent to which…

  8. Tribute to the legend Mr. Veterinary Public Health, Professor James ...

    African Journals Online (AJOL)

    The author was also destined during his Sabbatical Leave to have an interactive interview session with Prof James Steele after attending the 20th Annual James Steele lecture/ 99th birthday Dinner of Professor James Steele 4th and 6th April 2012 at the Texas School of Public Health, Houston, Texas, USA. The interview ...

  9. Postcards from a Road Trip to Innovation: One Professor's Sabbatical

    Science.gov (United States)

    Kelley, Todd R.

    2016-01-01

    Precious moments in life for an educator are taking time to reflect upon his or her teaching practices to evaluate effectiveness and overall impact. Often this reflection is a weekly if not a daily process for educators using a reflective practitioner model (SchÖn, 1983). For professors, many universities have opportunities for tenured faculty to…

  10. Humor and the Emeritus Professor: An Interview with Gene Roth

    Science.gov (United States)

    Vivona, Brian

    2015-01-01

    This essay is a compilation of several conversations with Dr. Gene Roth, Distinguished Teaching Professor Emeritus at Northern Illinois University. Dr. Roth is past President of the Academy of Human Resource Development, and although he is well known for his efforts in bringing humor into the field of HRD, he is not the same Gene Roth that played…

  11. An Examination of Assistant Professors' Project Management Practices

    Science.gov (United States)

    Alpert, Shannon Atkinson; Hartshorne, Richard

    2013-01-01

    Purpose: The purpose of this research was to identify factors that influence the use of project management in higher education research projects by investigating the project management practices of assistant professors. Design/methodology/approach: Using a grounded theory approach that included in-depth, semi-structured interviews with 22…

  12. Developing Student Character: Community College Professors Who Share Power

    Science.gov (United States)

    Humphreys, Connie K.

    2012-01-01

    This phenomenological study examined the definitions, values, and experiences of seven community college professors who have tried to promote student character development by sharing some of their power in the classroom. Power sharing is a participative gesture, and participative teachers can encourage students to become more engaged in their own…

  13. For Professors' Children, the Case for Home Schooling

    Science.gov (United States)

    Pannapacker, W. A.

    2005-01-01

    The number of families who home school their children is growing between five and 15% per year and it is believed that home schoolers outperform their public-educated peers, though critics believe that home schooling is a form of religious fanaticism and a means of avoiding diversity. A professor explains how he and his wife, home school their…

  14. "Women in Science" with Professor Jocelyn Bell Burnell

    Indian Academy of Sciences (India)

    2014-01-11

    January 11, 2014 | 11:30 am | Multimedia hall, New Physical Sciences Building. Chair, WiS panel of the IASc, Prof. Rohini Godbole, IISc will preside. “Women in Science”: an Interactive Discussion. Session with. Prof. Jocelyn Bell Burnell are happy to present. Prof. Dame Jocelyn Bell Burnell is currently a visiting Professor at ...

  15. The professor within the context of African Universities | Nenty ...

    African Journals Online (AJOL)

    It affirms that the professor is the soul of the university which itself is a world-wide liberal space for the development of the human intellect and genius. The paper further argues that when an individual has been able to satisfy the rigours of the professoriate, such an individual owes it as an obligation to impact positively ...

  16. Does Gender and Professional Experience Influence Students' Perceptions of Professors?

    Science.gov (United States)

    Tindall, Natalie T. J.; Waters, Richard D.

    2017-01-01

    Grounded in literature stemming from higher education research, this study examines how students evaluate public relations educators by gauging their perceptions of the professors' professional competency, professorial warmth, course difficulty, and industry connectivity. Using an experimental design, students (N = 303) from four U.S. universities…

  17. Professor GN Ramachandran's Contributions to X-ray Crystallography

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 6; Issue 10. Professor G. N. Ramachandran's Contributions to X-ray Crystallography. K Venkatesan. General Article Volume 6 Issue 10 October 2001 pp 8-15. Fulltext. Click here to view fulltext PDF. Permanent link:

  18. Ten Things Every Professor Should Know about Assessment

    Science.gov (United States)

    Wolf, Kenneth; Dunlap, Joanna; Stevens, Ellen

    2012-01-01

    This article describes ten key assessment practices for advancing student learning that all professors should be familiar with and strategically incorporate in their classrooms and programs. Each practice or concept is explained with examples and guidance for putting it into practice. The ten are: learning outcomes, performance assessments,…

  19. Professor-Student Rapport Scale: Six Items Predict Student Outcomes

    Science.gov (United States)

    Wilson, Janie H.; Ryan, Rebecca G.

    2013-01-01

    Rapport between students and teachers leads to numerous positive student outcomes, including attitudes toward the teacher and course, student motivation, and perceived learning. The recent development of a Professor-Student Rapport scale offers assessment of this construct. However, a Cronbach's [alpha] of 0.96 indicated item redundancy, and the…

  20. Dilemmas of a Newly Recruited Academic Qualified Professor: A Case

    Science.gov (United States)

    Agrawal, Anand

    2015-01-01

    This case describes the situation of a newly recruited academic professor who volunteered to teach a course on Research Methods to first-term MBA students in a practitioner-oriented case method Business School. Research Methods is a unique course due to its relevance not only in business but also across all graduate programs. Instructional and…

  1. Teaching the College "Nones": Christian Privilege and the Religion Professor

    Science.gov (United States)

    Riswold, Caryn D.

    2015-01-01

    Working with undergraduate students invites teachers into relationship and conversation with young people at a time when they are emerging as adults and forming their identities. Faith is one area of identity formation often attended to by scholars, college professors, and their institutions. But within that, little attention has been paid to…

  2. Identity Issues: Expatriate Professors Teaching and Researching in Qatar

    Science.gov (United States)

    Romanowski, Michael H.; Nasser, Ramzi

    2015-01-01

    Today, academics are more transient, working outside their home countries, than at any other time in the history of academics especially in the Arab World were there is great demand for faculty members educated in Western' culture and academia. However, many of these professors face considerable social, professional and academic challenges in…

  3. Reflections on Finally Becoming a Professor after Forty Years

    Science.gov (United States)

    Watkins, J. Foster

    2016-01-01

    I wrote this reflective piece in 1999 as I was assuming my first full-time position as a professor with limited administrative responsibilities at the University of Alabama at Birmingham (UAB). After 30-plus years in administrative roles in higher education that provided the opportunity to teach on a part-time basis only, I quickly became aware of…

  4. The rotor theories by Professor Joukowsky: Vortex theories

    DEFF Research Database (Denmark)

    Okulov, Valery L.; Sørensen, Jens Nørkær; Wood, David H.

    2015-01-01

    This is the second of two articles with the main, and largely self-explanatory, title "Rotor theories by Professor Joukowsky". This article considers rotors with finite number of blades and is subtitled "Vortex theories". The first article with subtitle "Momentum theories", assessed the starring ...

  5. Kant as a Professor: Some Lessons for Today's Intellectuals ...

    African Journals Online (AJOL)

    The thoughts of every great philosopher is measured and represented by the history of his social background. It is indeed, more appropriate particularly in the case of a great philosopher like Immanuel Kant to single out for special recognition the outstanding characteristics of his early life on his career as a professor of ...

  6. Reflections on the Scholarly Contributions of Professor David H. Jonassen

    Science.gov (United States)

    Reeves, Thomas C.; Lee, Chwee Beng; Hung, Woei

    2013-01-01

    The six papers in this special issue of "Computers and Education" honoring Professor David H. Jonassen are diverse in nature. They also reflect differing interpretations of the implications of Jonassen's work for research and development focused on instructional models and the factors influencing instruction as well as the directions for future…

  7. Championing Inclusion: An Interview with Professor Luanna Meyer

    Science.gov (United States)

    Bevan-Brown, Jill

    2012-01-01

    In May 2012, after a long and impressive career, Luanna Meyer retired from her role as Professor of Education and Director of the Jessie Hetherington Centre for Educational Research at Victoria University. The tributes paid at her retirement ceremony bear testament to a woman who is held in high esteem in the educational community. In this…

  8. On the Seminar of Professor Shulamit Kreitler in MSUPE

    Directory of Open Access Journals (Sweden)

    Fedorova A.I.

    2015-06-01

    Full Text Available From 9 to 15 of February, 2015 in Moscow state university of psychology and education hosted series of seminars of doctor of psychology Shulamit Kreitler. Dr. Kreitler is a professor of Tel-Aviv University, director of psychology studies center in Sheba medical center, Tel-Hashomer, Israel.

  9. On the Seminar of Professor Shulamit Kreitler in MSUPE

    OpenAIRE

    Fedorova A. I.; Scherbakova A.M.

    2015-01-01

    From 9 to 15 of February, 2015 in Moscow state university of psychology and education hosted series of seminars of doctor of psychology Shulamit Kreitler. Dr. Kreitler is a professor of Tel-Aviv University, director of psychology studies center in Sheba medical center, Tel-Hashomer, Israel.

  10. The Effect of Professor's Attractiveness on Distance Learning Students

    Science.gov (United States)

    Liu, Jeanny; Tomasi, Stella D.

    2015-01-01

    Technology enabled learning is becoming more popular and pervasive in education. While the effectiveness of distance learning versus traditional classroom education is strongly debated, human factors such as students' perception of their professors can influence their desire to learn. This research examines the perceptual effect of attractive…

  11. Career Vitality of Professors: A Cognitive Restructuring Model.

    Science.gov (United States)

    Bumpus, J. Frank

    An attributional model that conceptualizes the pressures that reduce professors' personal and career vitality is presented. The model is based primarily on the locus of control literature and especially the reformulated model of learned helplessness by Lynn Abramson, Martin Seligman, and John Teasdale. The analysis deals only with the cognitive…

  12. Could We Talk? Pragmatic Variations in Student-Professor Negotiations.

    Science.gov (United States)

    Biesenbach-Lucas, Sigrun; Weasenforth, Donald

    This study focuses on electronic office hour consultations and investigates the presence and organization of pragmatic elements associated with negotiating the completion and evaluation of coursework in the e-mail messages of 28 American and international students to an American professor. Findings indicate a lack of negotiation skills in the…

  13. Estimation of Asian dust aerosol effect on cloud radiation forcing using Fu-Liou radiative model and CERES measurements

    Directory of Open Access Journals (Sweden)

    Jing Su

    2008-05-01

    Full Text Available The impact of Asian dust on cloud radiative forcing during 2003–2006 is studied by using the Clouds and Earth's Radiant Energy Budget Scanner (CERES data and the Fu-Liou radiative transfer model. Analysis of satellite data shows that the dust aerosol significantly reduced the cloud cooling effect at TOA. In dust contaminated cloudy regions, the 4-year mean values of the instantaneous shortwave, longwave and net cloud radiative forcing are −138.9, 69.1, and −69.7 Wm−2, which are 57.0, 74.2, and 46.3%, respectively, of the corresponding values in pristine cloudy regions. The satellite-retrieved cloud properties are significantly different in the dusty regions and can influence the radiative forcing indirectly. The contributions to the cloud radiation forcing by the dust direct, indirect and semi-direct effects are estimated using combined satellite observations and Fu-Liou model simulation. The 4-year mean value of combination of dust indirect and semi-direct shortwave radiative forcing (SWRF is 82.2 Wm−2, which is 78.4% of the total dust effect. The dust direct effect is only 22.7 Wm−2, which is 21.6% of the total effect. Because both first and second indirect effects enhance cloud cooling, the aerosol-induced cloud warming is mainly the result of the semi-direct effect of dust.

  14. Refletindo sobre a relação professor-aluno em um grupo de professores do Esino Fundamental

    Directory of Open Access Journals (Sweden)

    Antônio dos Santos Andrade

    1999-06-01

    Full Text Available A partir das concepções de Donald Schön sobre a formação do professor como prático reflexivo, os princípios de trabalho com pequenos grupos, baseados nas concepções de J. L Moreno, foram utilizados com o objetivo de facilitar o processo de reflexão sobre suas práticas de sala de aula, com seis professores do Ensino Fundamental. Foram realizados nove encontros de 90 a 120 minutos de duração. Nas discussões, os casos dos alunos mais problemáticos quanto ao seu comportamento foram trazidos pelos professores e analisados pelo grupo a luz das concepções da Pragmática da Comunicação Humana. Como resultado destas discussões, os professores foram levados a considerar os aspectos mais latentes, e portanto significantes, de suas relações com os alunos. Estas reflexões conduziram a uma "resignificação" das mesmas, com efeitos surpreendentes sobre os comportamentos dos alunos.

  15. Why Did the Professor Cross the Road? How and Why College Professors Intentionally Use Humor in Their Teaching

    Science.gov (United States)

    Buckman, Karen Hildebrant

    2010-01-01

    College professors face many pressing challenges: staying current in their disciplines, becoming familiar with new technology, responding to national accountability issues, publishing scholarly research in their fields, and facilitating student learning in their classes. Teaching and learning are complex processes. Humor is a powerful…

  16. Yue Joseph Wang named Grant A. Dove Professor of Electrical and Computer Engineering

    OpenAIRE

    Owczarski, Mark

    2009-01-01

    Yue Joseph Wang, professor of electrical and computer engineering in the College of Engineering at Virginia Tech, has been named the Grant A. Dove Professor of Electrical and Computer Engineering by the Virginia Tech Board of Visitors.

  17. Maury Nussbaum reappointed as Hal G. Prillaman Professor Fellow in Industrial and Systems Engineering

    OpenAIRE

    Owczarski, Mark

    2010-01-01

    Maury Nussbaum, professor of industrial and systems engineering in the College of Engineering at Virginia Tech, has been reappointed as the Hal G. Prillaman Professor Fellow in Industrial and Systems Engineering by the Virginia Tech Board of Visitors.

  18. Brian M. Kleiner receives Ralph H. Bogle Professor Fellowship in Industrial and Systems Engineering

    OpenAIRE

    Owczarski, Mark

    2010-01-01

    Brian M. Kleiner, professor of industrial and systems engineering in the College of Engineering at Virginia Tech, has been named the Ralph H. Bogle Professor Fellow in Industrial and Systems Engineering by the Virginia Tech Board of Visitors.

  19. Wheat germ allutinin functionalized crosslinked polyelectrolyte microparticles for local colon delivery of 5-FU: In vitro efficacy and in vivo gastrointestinal distribution

    DEFF Research Database (Denmark)

    Glavas-Dodov, Marija; Steffansen, Bente; Crcarevska, Maja

    2013-01-01

    We have previously reported the development and characterisation of wheat germ agglutinin (WGA)-functionalised chitosan-Ca-alginate (CTS-Ca-ALG) microparticles (MPs) loaded with acid-resistant particles of 5-fluorouracil (5-FU). In the present work, our goal was to evaluate the potential of these...

  20. The Effects of Professors' Race and Gender on Student Evaluations and Performance

    Science.gov (United States)

    Basow, Susan A.; Codos, Stephanie; Martin, Julie L.

    2013-01-01

    This experimental study examined the effects of professor gender, professor race, and student gender on student ratings of teaching effectiveness and amount learned. After watching a three-minute engineering lecture presented by a computer-animated professor who varied by gender and race (African American, White), female and male undergraduates…

  1. The Association of Professors' Style, Trait Anxiety, and Experience with Students' Grades.

    Science.gov (United States)

    Theodory, George C.; Day, Richard C.

    1985-01-01

    The relationship between the style, trait anxiety, and experience of professors and students' grades was investigated using Fiedler's contingency theory. Results indicated professors' trait anxiety is significant influencing student grades; professors having a high Least Preferred co-worker score assigned grades negatively correlated related with…

  2. Professors and Coaches Educational Approaches That Support the NCAA Division III Student Athlete Experience

    Science.gov (United States)

    Kuntz, Daniel E.

    2011-01-01

    While professors and coaches have the ability to enable or impede student athletes' educational success in college, studies that address the perspectives of coaches and professors about their interactions with student athletes are limited. This study aimed to understand (a) the ways in which professors and coaches who act as institutional agents…

  3. A Mixed Analysis of College Students' Best and Poorest College Professors

    Science.gov (United States)

    Slate, John R.; LaPrairie, Kimberly; Schulte, Don P.; Onwuegbuzie, Anthony J.

    2009-01-01

    In this study, the authors examined the views of 171 college students concerning their best and poorest college professors. In a multi-stage conversion mixed analysis design, students' stories of their best and poorest college professors were thematically analysed, resulting in 15 dominant themes for their best college professors and 12 dominant…

  4. A Changing Role for University Professors? Professorial Academic Leadership as It Is Perceived by "The Led"

    Science.gov (United States)

    Evans, Linda

    2015-01-01

    This article examines the academic leadership role of university professors in the UK (a grade title which in that national context generally refers only to the most distinguished, senior academics, who equate to the North American full professor). Drawing on theoretical interpretations of professionalism and applying these to professors, it…

  5. PREFACE: Special section on Computational Fluid Dynamics—in memory of Professor Kunio Kuwahara Special section on Computational Fluid Dynamics—in memory of Professor Kunio Kuwahara

    Science.gov (United States)

    Ishii, Katsuya

    2011-08-01

    This issue includes a special section on computational fluid dynamics (CFD) in memory of the late Professor Kunio Kuwahara, who passed away on 15 September 2008, at the age of 66. In this special section, five articles are included that are based on the lectures and discussions at `The 7th International Nobeyama Workshop on CFD: To the Memory of Professor Kuwahara' held in Tokyo on 23 and 24 September 2009. Professor Kuwahara started his research in fluid dynamics under Professor Imai at the University of Tokyo. His first paper was published in 1969 with the title 'Steady Viscous Flow within Circular Boundary', with Professor Imai. In this paper, he combined theoretical and numerical methods in fluid dynamics. Since that time, he made significant and seminal contributions to computational fluid dynamics. He undertook pioneering numerical studies on the vortex method in 1970s. From then to the early nineties, he developed numerical analyses on a variety of three-dimensional unsteady phenomena of incompressible and compressible fluid flows and/or complex fluid flows using his own supercomputers with academic and industrial co-workers and members of his private research institute, ICFD in Tokyo. In addition, a number of senior and young researchers of fluid mechanics around the world were invited to ICFD and the Nobeyama workshops, which were held near his villa, and they intensively discussed new frontier problems of fluid physics and fluid engineering at Professor Kuwahara's kind hospitality. At the memorial Nobeyama workshop held in 2009, 24 overseas speakers presented their papers, including the talks of Dr J P Boris (Naval Research Laboratory), Dr E S Oran (Naval Research Laboratory), Professor Z J Wang (Iowa State University), Dr M Meinke (RWTH Aachen), Professor K Ghia (University of Cincinnati), Professor U Ghia (University of Cincinnati), Professor F Hussain (University of Houston), Professor M Farge (École Normale Superieure), Professor J Y Yong (National

  6. Analytical estimation of annual runoff distribution in ungauged seasonally dry basins based on a first order Taylor expansion of the Fu's equation

    Science.gov (United States)

    Caracciolo, D.; Deidda, R.; Viola, F.

    2017-11-01

    The assessment of the mean annual runoff and its interannual variability in a basin is the first and fundamental task for several activities related to water resources management and water quality analysis. The scarcity of observed runoff data is a common problem worldwide so that the runoff estimation in ungauged basins is still an open question. In this context, the main aim of this work is to propose and test a simple tool able to estimate the probability distribution of the annual surface runoff in ungauged river basins in arid and semi-arid areas using a simplified Fu's parameterization of the Budyko's curve at regional scale. Starting from a method recently developed to derive the distribution of annual runoff, under the assumption of negligible inter-annual change in basin water storage, we here generalize the application to any catchment where the parameter of the Fu's curve is known. Specifically, we provide a closed-form expression of the annual runoff distribution as a function of the mean and standard deviation of annual rainfall and potential evapotranspiration, and the Fu's parameter. The proposed method is based on a first order Taylor expansion of the Fu's equation and allows calculating the probability density function of annual runoff in seasonally dry arid and semi-arid geographic context around the world by taking advantage of simple easy-to-find climatic data and the many studies with estimates of the Fu's parameter worldwide. The computational simplicity of the proposed tool makes it a valuable supporting tool in the field of water resources assessment for practitioners, regional agencies and authorities.

  7. E2F1/TS Immunophenotype and Survival of Patients with Colorectal Cancer Treated with 5FU-Based Adjuvant Therapy.

    Science.gov (United States)

    Sulzyc-Bielicka, Violetta; Domagala, Pawel; Bielicki, Dariusz; Safranow, Krzysztof; Rogowski, Wojciech; Domagala, Wenancjusz

    2016-07-01

    The predictive value of thymidylate synthase (TS) expression alone for 5FU-based treatment of colorectal cancer (CRC) has not been clinically confirmed. Little is known on the association of expression of E2F1, which controls the transcription of genes encoding proteins engaged in DNA synthesis including TS, and survival of patients with CRC. The purpose of this study is to assess the correlation between expression of both E2F1 and TS in CRCs and survival of patients administered adjuvant 5FU-based chemotherapy, in order to find a better predictor of treatment outcome than expression of TS or E2F1 alone. Nuclear TS and E2F1 were detected by immunohistochemistry in tissue microarrays from 190 CRCs (Astler-Coller stage B2 or C). Multivariate analysis identified significant association of the combined E2F1+TS+ immunophenotype with worse OS (HR = 3,78, P = 0,009) and DFS (HR = 2,30, P = 0,03) of patients with colon cancer. There were significant differences between E2F1+TS+ and E2F1-TS- Kaplan-Meier survival curves in relation to DFS (P = 0.008) and OS (P = 0.01). About 37 and 31 % difference in 3-year DFS and OS respectively were seen between patients with E2F1+TS+ vs. E2F1-TS- colon cancer immunophenotype. The E2F1+TS+ immunophenotype may be a marker of poor prognosis (the worst DFS and OS) of patients with colon cancer treated with 5FU-based adjuvant therapy. A subgroup of patients with this immunophenotype may require different and perhaps more aggressive treatment than 5FU-based chemotherapy. Thus, the combined E2F1/TS immunophenotype could be a potential indicator of colon cancer sensitivity to 5FU.

  8. 5-FU or mitomycin C hepatic arterial infusion after failure of arterial oxaliplatin in patients with colorectal cancer unresectable liver metastases.

    Science.gov (United States)

    Pernot, Simon; Velut, Guillaume; Kourie, Rapahel Hampig; Amouyal, Gregory; Sapoval, Marc; Pointet, Anne Laure; Landi, Bruno; Zaimi, Yosra; Lepère, Céline; Pellerin, Olivier; Taieb, Julien

    2017-12-07

    Hepatic arterial infusion (HAI) chemotherapy with oxaliplatin is an accepted option in the management of colorectal cancer (CRC) with dominant liver metastases (LM). However, despite prolonged control, some patients experience disease progression. On the other hand, oxaliplatin leads to dose-limiting toxicity. In these cases, the use of a second-line HAI with an alternative drug has never been reported to date. We evaluated treatment outcomes in patients receiving second-line HAI with 5-FU or mitomycin C, after first-line HAI of oxaliplatin in heavily pretreated patients. Between March 2010 and June 2016, this observational study included 24 patients with unresectable CRC LM and treated with HAI of 5-FU (17 patients) or mitomycin C (7 patients), after HAI of oxaliplatin. Mean age was 61.7 years. Forty-two percent of patients (10/24) had extra-hepatic metastases and 75% (18/24) at least 8 liver metastases. Including HAI of oxaliplatin, all patients had previously received at least 2 lines of chemotherapy±targeted agents (100%) and 96% (23/24) received concomitant systemic therapies together with HAI of 5-FU or mitomycin C. The overall objective response rate and disease control rate were, respectively, 42% (10/24) and 71% (17/24). Median progression-free survival and overall survival (OS) were, respectively, 5.6 and 25.8 months; hepatic progression-free survival was 8.5months. Thirteen percent (3/24) of the patients received further curative intent treatment after HAI 5-FU and mitomycin C. No toxic death occurred and the toxicity profile was acceptable. HAI of 5-FU or mitomycin C is an alternative option in patients with predominant CRC LM, when they experience disease progression or do not tolerate HAI of oxaliplatin. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  9. The efficiency of CD40 down regulation by siRNA and antisense ODN: comparison of lipofectamine and FuGENE6.

    Science.gov (United States)

    Ebadi, Padideh; Karimi, Mohammad Hossein; Pourfathollah, Ali Akbar; Saheb Ghadam Lotfi, Abbas; Soheili, Zahra Soheila; Samiee, Shahram; Hajati, Smerdis; Nadali, Fatemeh; Geramizadeh, Bita; Moazzeni, Seyyed Mohammad

    2009-03-01

    Dendritic cells (DCs) are ideal accessory cells in the field of gene therapy. Delivery of DNA and siRNA into mammalian cells is a useful technique in treating various diseases caused by single gene defects. Selective gene silencing by small interfering RNAs (siRNAs) and antisense oligodeoxynucleotides (ODN)s is an efficient method for the manipulation of cellular functions. An efficient, functional delivery system with no toxicity problems would be attractive. We compared two commercially available cationic lipids, Lipofectamine and FuGENE6, in the delivery of both siRNA and antisense ODNs into mice spleen-derived DCs. Cellular uptake was measured by the means of fluorescein-labelled non-silencing siRNA and antisense ODNs as a model system using flow cytometry. Cytotoxicity of the two delivery systems was compared with propidium iodide and annexin-V staining, and quantified with flow cytometry. The efficiency of our oligonucleotide delivery systems was compared by measuring CD40 expression by flow cytometry. CD40 expression in DCs was 38%. After siRNA transfection by Lipofectamine, CD40 expression decreased to 13%, and after transfection by FuGENE6, it decreased to 18%. The difference was statistically significant. CD40 down regulation in DCs transfected with the two different antisense sequences by Lipofectamine was 21% and 23%, and down regulation after transfection by FuGENE6 was 19% and 18%, respectively. The differences were not statistically significant. The effects of siRNA and antisense ODNs were specific. Lipofectamine was a more potent delivery system in siRNA effect, followed by FuGENE6. There was no significant difference between Lipofectamine and FuGENE6 as a delivery system of antisense ODNs.

  10. Combined 5-FU and ChoKα inhibitors as a new alternative therapy of colorectal cancer: evidence in human tumor-derived cell lines and mouse xenografts.

    Directory of Open Access Journals (Sweden)

    Ana de la Cueva

    Full Text Available Colorectal cancer (CRC is the third major cause of cancer related deaths in the world. 5-fluorouracil (5-FU is widely used for the treatment of colorectal cancer but as a single-agent renders low response rates. Choline kinase alpha (ChoKα, an enzyme that plays a role in cell proliferation and transformation, has been reported overexpressed in many different tumors, including colorectal tumors. ChoKα inhibitors have recently entered clinical trials as a novel antitumor strategy.ChoKα specific inhibitors, MN58b and TCD-717, have demonstrated a potent antitumoral activity both in vitro and in vivo against several tumor-derived cell line xenografts including CRC-derived cell lines. The effect of ChoKα inhibitors in combination with 5-FU as a new alternative for the treatment of colon tumors has been investigated both in vitro in CRC-tumour derived cell lines, and in vivo in mouse xenografts models. The effects on thymidilate synthase (TS and thymidine kinase (TK1 levels, two enzymes known to play an essential role in the mechanism of action of 5-FU, were analyzed by western blotting and quantitative PCR analysis. The combination of 5-FU with ChoKα inhibitors resulted in a synergistic effect in vitro in three different human colon cancer cell lines, and in vivo against human colon xenografts in nude mice. ChoKα inhibitors modulate the expression levels of TS and TK1 through inhibition of E2F production, providing a rational for its mechanism of action.Our data suggest that both drugs in combination display a synergistic antitumoral effect due to ChoKα inhibitors-driven modulation of the metabolization of 5-FU. The clinical relevance of these findings is strongly supported since TCD-717 has recently entered Phase I clinical trials against solid tumors.

  11. CANER, Daniel F. (Liverpool, 2010), History and Hagiography fom Late Antique Sinai, including translations of Pseudo Nilus’ Narrations of Sinai and Raithou, and Anastasious of Sinai’s Tales of the Sinai Fathers, with contributions of Sebastian Brock, Richard M. Price and Kevin van Bladel

    OpenAIRE

    Monferrer-Sala, J.P.

    2010-01-01

    Reseña de: History and Hagiography fom Late Antique Sinai, including translations of Pseudo Nilus’ Narrations of Sinai and Raithou, and Anastasious of Sinai’s Tales of the Sinai Fathers, with contributions of Sebastian Brock, Richard M. Price and Kevin van Bladel

  12. Professor Peter Higgs: "My Life as a Boson"

    CERN Multimedia

    CERN. Geneva

    2012-01-01

    Professor Peter Higgs played a key role in the development of the Standard Model, our current theory of fundamental physics. The search for the Higgs Boson is the centrepiece of the LHC programme at CERN, and the existence of this famously elusive particle is likely to be confirmed or refuted with data currently being collected, using apparatus partly designed at Bristol. Professor Higgs will introduce the ideas of spontaneous symmetry breaking, and discuss how these developed from their application in condensed matter through the earlier work of Yoichiro Nambu and Jeffrey Goldstone, to the work of Robert Brout, Francois Englert and himself in 1964. The subsequent application of these ideas to electroweak theory will be discussed briefly.

  13. An Outstanding Career: Professor Emeritus Iacob Cătoiu

    Directory of Open Access Journals (Sweden)

    Octavian Oprică

    2016-05-01

    Full Text Available Through the duration of his commissions of Deputy Dean (1981-1989 and, respectively, Dean (1992-2003, and also by the manner of approaching the managerial problems and his scientific extension, Professor Iacob Cătoiu left and indelible trace on the evolution of the former Department of Commerce in the Bucharest University of Economic Studies (ASE – now the Department of Business and Tourism. He is author or co-author of an important number of books (57 and articles (105 and book presentations. Thus, after he made the personal acquaintance with Philip Kotler, the guru of international marketing, in 1997, Professor Iacob Cătoiu wrote the Forward to the Romanian version of Philip Kotler's volume Managementul marketingului (Marketing Management a fundamental book in its field. (Nicolae Lupu

  14. PHYSICAL ACTIVITY AND EATING HABITS IN UNIVERSITY PROFESSORS: LITERATURE REVIEW

    Directory of Open Access Journals (Sweden)

    Hector Luiz Rodrigues Munaro

    2015-01-01

    Full Text Available Increasingly, university professors engage in academic tasks often stressful and sedentary behaviors, making the practice of physical activity and healthier eating habits. The aim of this study was to review the literature Brazilian studies on physical activity and eating habits of university professors .The search was conducted between March and May 2013, in electronic databases. For the delimitation of the study, was used as descriptors: Physical Activity, University Teachers and Eating Habits. At the end of the article selection process, remaining 06 studies that have been described and discussed in the text. And all of a descriptive nature, with small samples with some robust and consistent methodology. The selected studies, regardless of their qualities, point to the need of this population to engage in more physical activity and healthy eating habits programs

  15. The University Professor View from the Communitarian Perspective

    Directory of Open Access Journals (Sweden)

    Angela Del Valle López

    2014-04-01

    Full Text Available The task of the university professor is a mission and not simply a profession and that is why higher education should be impregnated with values. Nowadays education is articulated into three areas: the State, the Market and the Volunteering, but no one of these three sectors by themselves has covered the needs of all the citizens, there have always been losers, therefore the conjunction of the three sectors became necessary. Communitarianism promotes an ethical-social pact that favors the progress of society without nullifying the individual dimension. It believes that the university is the space where a communitarian consciousness should be promoted to generate a social capital by means of education and it is a privilege place to substantiate the moral identity of the person beginning with the commitment of the professor with the university student.

  16. PHYSICAL ACTIVITY AND EATING HABITS IN UNIVERSITY PROFESSORS: LITERATURE REVIEW

    Directory of Open Access Journals (Sweden)

    Hector Luiz Rodrigues Munaro

    2015-03-01

    Full Text Available Increasingly, university professors engage in academic tasks often stressful and sedentary behaviors, making the practice of physical activity and healthier eating habits. The aim of this study was to review the literature Brazilian studies on physical activity and eating habits of university professors .The search was conducted between March and May 2013, in electronic databases. For the delimitation of the study, was used as descriptors: Physical Activity, University Teachers and Eating Habits. At the end of the article selection process, remaining 06 studies that have been described and discussed in the text. And all of a descriptive nature, with small samples with some robust and consistent methodology. The selected studies, regardless of their qualities, point to the need of this population to engage in more physical activity and healthy eating habits programs.

  17. [The professor-student relationship in coping with dying].

    Science.gov (United States)

    Pinho, Líũcia Maria Oliveira; Barbosa, Maria Alves

    2010-03-01

    The new guidelines for undergraduate courses in the field of health care imply a need to prepare professionals to deal with life and death. To study death and dying in the context of nurse education means to contribute to the humanization of education and to preparing humanistic and critical professionals. We performed individual interviews with professors so that each could reveal their thoughts about experiencing death and dying in the educational relationship between nurse/professor and the nursing student in the hospital environment. Content analysis was performed using ideas close to those of Heidegger, revealing that education towards the concept and experience of death appears to be possible only if there is reflection regarding human existence, thoughts, and accepting finitude. By understanding one's own attitudes towards death and existence, it is possible to perceive possibilities in education for care in the death process.

  18. The university professor: integration between the personal and professional dimension

    Directory of Open Access Journals (Sweden)

    José Javier BERMÚDEZ-APONTE

    2017-12-01

    Full Text Available In the first part of this article, the authors explain how the teaching role is affected by certain social and cultural changes, like the knowledge society emergence, the universities orientation towards marketing, the constant demand and pressure exerted on teachers to publish, the loss of the ethical sense in the academic activity and the disparity of tasks that are being assigned to the university professors. In view of the above, a comprehensive model, compound by two concepts –personal and professional– of a university professor is proposed; in fact, this model incorporates and summarises different contributions regarding this theme. Finally, this article aims to defend the need to understand the teaching role as a vocation, in the broadest sense of the word, a vocation carries the inclination to pursue an aim: the education of those students that teachers have in charge.

  19. [Analysis of professor WU Lianzhong's experience of neck acupoints application].

    Science.gov (United States)

    Peng, Jiandong; Zheng, Hongyan; Wang, Yingshu

    2015-09-01

    Professor WU Lianzhong's experience of neck acupoints application is introduced. The characteristics,locations, acupuncture manipulations ,efficiency and main functions of neck acupoints including Tiandixue (Extra), Jingbixue (Extra), and cervical Jiaji (EX-B 2) are stated. According to the TCM thought of treatment based on syndrome differentiation,WU Lianzhong's special theory of neck acupoints application is explained so as to provide experience for improving acupuncture effects.

  20. YouTube Professors Scholars as Online Video Stars

    Science.gov (United States)

    Young, Jeffrey R.

    2008-01-01

    This article takes a look at how professors are becoming the latest YouTube stars. The popularity of their appearances on YouTube and other video-sharing sites end up opening the classroom and making teaching--which once took place behind closed doors--a more public art. Web videos open a new form of public intellectualism to scholars looking to…

  1. YouTube Professors: Scholars as Online Video Stars

    Science.gov (United States)

    Young, Jeffrey R.

    2008-01-01

    This article takes a look at the rising popularity of professors as the latest YouTube stars. The popularity of their appearances on YouTube and other video-sharing sites is making it possible for classrooms to be opened up and making teaching--which once took place behind closed doors--a more public art. Web video has generated a new form of…

  2. Professor V. Weisskopf, CERN Director General (1961-1965)

    CERN Multimedia

    1962-01-01

    Well known theoretical physicist Victor Weisskopf has died aged 93. Born in Austria, he later worked with Schrodinger in Berlin before emigrating to the US in 1937, where he joined the Manhattan project in 1944, and was witness to the Trinity Test in July 1945. In 1946 he became professor of physics at MIT. He took leave of absence to be Director General of CERN, the European Organization for Nuclear Physics, from 1961-1965.

  3. Professor Created On-line Biology Laboratory Course

    Science.gov (United States)

    Bowman, Arthur W.

    2010-01-01

    This paper will share the creation, implementation, and modification of an online college level general biology laboratory course offered for non-science majors as a part of a General Education Curriculum. The ability of professors to develop quality online laboratories will address a growing need in Higher Education as more institutions combine course sections and look for suitable alternative course delivery formats due to declining departmental budgets requiring reductions in staffing, equipment, and supplies. Also, there is an equal or greater need for more professors to develop the ability to create online laboratory experiences because many of the currently available online laboratory course packages from publishers do not always adequately parallel on-campus laboratory courses, or are not as aligned with the companion lecture sections. From a variety of scientific simulation and animation web sites, professors can easily identify material that closely fit the specific needs of their courses, instructional environment, and students that they serve. All too often, on-campus laboratory courses in the sciences provide what are termed confirmation experiences that do NOT allow students to experience science as would be carried out by scientists. Creatively developed online laboratory experiences can often provide the type of authentic investigative experiences that are not possible on-campus due to the time constraints of a typical two-hour, once-per-week-meeting laboratory course. In addition, online laboratory courses can address issues related to the need for students to more easily complete missing laboratory assignments, and to have opportunities to extend introductory exercises into more advanced undertakings where a greater sense of scientific discovery can be experienced. Professors are strongly encourages to begin creating online laboratory exercises for their courses, and to consider issues regarding assessment, copyrights, and Intellectual Property

  4. Professors, principals and textbooks from the Midwifery school in Zadar.

    Science.gov (United States)

    Maksimović, Jovan; Maksimović, Marko

    2017-06-01

    Midwifery in Dalmatia was highly undeveloped at the beginning of the XIX century. The health report from 1813 suggested that there were only 48 midwives in the whole province, and none of them with a degree from the midwifery school. After abolishing the Central Schools ("Ecoles Centrales"), which were founded at the time of French reign, and which had the university range, the professors who stayed in Zadar continued their work and teaching in the Midwifery School, which was founded in 1820 according to the decision made by Emperor Franz I, and started working in 1821. Since the school was working continuously for the whole century, a lot of professors and principals passed through. Protomedicus of Dalmatia officially performed the duty of principals of the Midwifery School. Their life and work biographies were gathered in this paper. Although the newcomers were mostly illiterate, very contemporary and valuable textbooks were used at that time. The professors of this school wrote some of these textbooks. This paper analyses those textbooks from the current medical science and praxis point of view, which points out to its significance and contribution of its authors to the reputation that the School enjoyed at that time.

  5. Comunidades em processos formativos de professores de ciências

    Directory of Open Access Journals (Sweden)

    Willian Rubira da Silva

    2017-12-01

    Full Text Available Apresentamos compreensões sobre as diferentes concepções de comunidade dentro do contexto da formação de professores de Ciências. Termos relacionados a comunidades no contexto de ensino e aprendizagem vem se tornando genéricos, dificultando compreensões de trabalhos da área no Brasil. Visualizamos a necessidade de significar concepções do termo em questão no contexto da sociologia e psicologia para então avançar nas compreensões mais abrangentes dentro da educação. Ampliamos o estudo com uma revisão dos trabalhos publicados nos anais do Encontro Nacional de Pesquisa em Educação em Ciências correlacionando a formação de professores com as perspectivas teórico-práticas de comunidades em contexto educacional. Escolhemos os anais deste evento por ser um ponto de debate entre os pesquisadores na área de Educação em Ciências e que, desta maneira, nos possibilitou sistematizar diferentes concepções de comunidades. Essas foram agrupadas em 7 categorias emergentes distintas por aspectos teórico-práticos utilizados nos processos formativos de professores de Ciências.

  6. Phase II study of neoadjuvant 5-FU + leucovorin + CPT-11 in patients with resectable liver metastases from colorectal adenocarcinoma

    Directory of Open Access Journals (Sweden)

    Bigam David

    2004-07-01

    Full Text Available Abstract Background Following resection of liver metastases from colorectal cancer, 5-year survivals are reportedly 30 – 39%. It can be assumed that this clinical situation represents systemic disease. Therefore, it is postulated that systemic chemotherapy would improve outcomes, particularly in those whose disease is sensitive to the agents administered. One potential advantage of neoadjuvant chemotherapy is that it provides in vivo chemosensitivity data. Response to neoadjuvant chemotherapy could therefore guide adjuvant chemotherapy following resection of liver metastases from colorectal cancer. Methods and design This is a prospective Phase II evaluation of outcomes in patients with potentially resectable liver metastases. Patients will receive neoadjuvant chemotherapy and will undergo resection. Postoperative chemotherapy will be directed by the degree of response to preoperative chemotherapy. All patients with Stage IV colorectal adenocarcinoma isolated to the liver that have disease that is amenable to complete ablation by resection, radiofrequency ablation, and/or cryoablation will be candidates for the trial. Patients will receive CPT-11 180 mg/m2 IV (over 90 minutes on day 1 with 5-FU 400 mg/m2 bolus and 600 mg/m2 by 22 hour infusion and calcium folinate 200 mg/m2 on days 1 and 2, every 2 weeks. Altogether, six cycles of chemotherapy will be administered. Patients will then undergo resection and/or radiofrequency ablation. Patients who had stable disease or a clinical response with preoperative chemotherapy will receive an additional 12 cycles of CPT-11 180 mg/m2 IV (over 90 minutes on day 1 with 5-FU 400 mg/m2 bolus and 600 mg/m2 by 22 hour infusion and calcium folinate 200 mg/m2 on days 1 and 2 (given every 2 weeks. Patients with resectable disease who had progressive disease during neoadjuvant chemotherapy will receive best supportive care or an alternative agent, at the discretion of the treating physician. Those patients who are

  7. The Many Sides of Happy Lim: aka Hom Ah Wing, Lin Jian Fu, Happy Lum, Lin Chien Fu, Hom Yen Chuck, Lam Kin Foo, Lum Kin Foo, Hom, Lim Goon Wing, Lim Gin Foo, Gin Foo Lin, Koon Wing Lim, Henry Chin, Lim Ying Chuck, Lim Ah Wing, et. al.

    Directory of Open Access Journals (Sweden)

    Gordon H. Chang

    2010-03-01

    Full Text Available

    Known to the FBI, INS, and IRS as Mr. Ah Wing Hom, he was also Lin Jian Fu, Jian Fu (Tough Guy, or just Fu to the readers of the many poems and short stories he published in Chinese over four decades in the twentieth century. And to still others, primarily English-readers of his writing, he was Happy Lim, an ironic, even tragically bizarre name, as his life was far from pleasant. On New Year's Day 1986, he died alone in a dingy San Francisco Chinatown bachelor hotel suffering from a bacterial infection and a chronic blood disorder that had required the amputation of all his toes the year before. He was seventy-eight years of age and had spent most of his life within blocks of where he died.

  8. The Many Sides of Happy Lim: aka Hom Ah Wing, Lin Jian Fu, Happy Lum, Lin Chien Fu, Hom Yen Chuck, Lam Kin Foo, Lum Kin Foo, Hom, Lim Goon Wing, Lim Gin Foo, Gin Foo Lin, Koon Wing Lim, Henry Chin, Lim Ying Chuck, Lim Ah Wing, et. al.

    Directory of Open Access Journals (Sweden)

    Gordon H. Chang

    2010-03-01

    Full Text Available Known to the FBI, INS, and IRS as Mr. Ah Wing Hom, he was also Lin Jian Fu, Jian Fu (Tough Guy, or just Fu to the readers of the many poems and short stories he published in Chinese over four decades in the twentieth century. And to still others, primarily English-readers of his writing, he was Happy Lim, an ironic, even tragically bizarre name, as his life was far from pleasant. On New Year's Day 1986, he died alone in a dingy San Francisco Chinatown bachelor hotel suffering from a bacterial infection and a chronic blood disorder that had required the amputation of all his toes the year before. He was seventy-eight years of age and had spent most of his life within blocks of where he died.

  9. Volume celebrating the 60th birthday of Professor Dr. Franz Fie; Professor Dr. Franz Fiedler zum 60. Geburtstag

    Energy Technology Data Exchange (ETDEWEB)

    Beheng, K.D. [ed.

    1998-01-01

    This report was compiled in honor of Professor Dr. Franz Fiedler on the occasion of his 60th birthday on 7 January 1998. Its contributions deal with mesoscale modelling, the propagation of air pollutants, measurements of precipitation using radar, and prediction models. (orig./KW) [Deutsch] Dieser Bericht wurde aus Anlass des 60. Geburtstags von Herrn Prof. Dr. Franz Fiedler am 7. Januar 1998 zusammengestellt. Die Beitraege behandeln mesoskalige Modellierung, Ausbreitung von Luftschadstoffen, Niederschlagsmessung mit Radar und Vorhersagemodelle. (orig.)

  10. ELECTROMYOGRAPHIC STUDY OF A SEQUENCE OF YAU-MAN KUNG FU PALM STRIKES WITH AND WITHOUT IMPACT

    Directory of Open Access Journals (Sweden)

    Osmar Pinto Neto

    2007-10-01

    Full Text Available In martial arts and contact sports, strikes are often trained in two different ways: with and without impacts. This study aims to compare the electromyographical activity (EMG of the triceps brachii (TB, biceps brachii (BB and brachioradialis (BR muscles during strikes with and without impacts. Eight Yau-Man Kung Fu practitioners participated in the experiment. Each participant performed 5 sequences of 5 consecutive KF Yau-Man palm strikes with no impact intercalated with 5 sequences of 5 repetitions targeting a KF training shield. Surface EMG signals were obtained from the TB, BB, and RB for 3.0 seconds using an eight-channel module with a total amplifier gain of 2000 and sampled at 3500 Hz. The EMG analyses were done in the time (rms and frequency (wavelet domains. For the frequency domain, Morlet wavelet power spectra were obtained and an original method was used to quantify statistically significant regions on the power spectra. The results both in the time and frequency domains indicate a higher TB and BR muscle activity for the strikes with impacts. No significant difference was found for the BB in the two different scenarios. In addition, the results show that the wavelet power spectra pattern for the three analysed muscles obtained from the strikes with and without impacts were similar

  11. Epigenetic silencing of ASPP1 confers 5-FU resistance in clear cell renal cell carcinoma by preventing p53 activation.

    Science.gov (United States)

    Wang, Xingwen; Cheng, Yiwei; Zhu, YiFu; Li, Huayi; Ge, Wenjie; Wu, Xiaoliang; Zhao, Kunming; Yuan, Jinyang; Li, Zhenglin; Jiang, Shijian; Han, Zhengbin; Jiang, Qinghua; Wu, Qiong; Liu, Tao; Zhang, Cheng; Yu, Miao; Hu, Ying

    2017-10-01

    Inactivation of p53 has been shown to correlate with drug resistance in tumors. However, in clear cell renal cell carcinoma (ccRCC), p53 is rarely mutated, yet the tumors remain highly insensitive to the conventional chemotherapeutic drugs. The underlying mechanisms responsible for the non-genetic p53 inactivation remain obscure. Here, we report, for the first time, that Apoptosis Stimulating of P53 Protein 1 (ASPP1) was remarkably downregulated at both mRNA (about 3.9-fold) and protein (about 4.9-fold) levels in ccRCC human specimens in comparison with the paired normal controls. In addition, lower ASPP1 was closely related to the higher grade of tumors and shorter life expectancy of ccRCC patients, both with p p53 targets expression and p53 target PIG3 luciferase reporter activation. In contrast, ASPP1 knockdown promoted cell growth and prevent 5-FU-induced p53 activation and apoptosis. In conclusion, our results suggest that ASPP1 silencing is one of dominate mechanisms in inhibiting wild type p53 in ccRCC. ASPP1, therefore, may be potentially used as a promising biomarker for prognosis and therapeutic intervention in ccRCC. © 2017 UICC.

  12. Technical note: Fu-Liou-Gu and Corti-Peter model performance evaluation for radiative retrievals from cirrus clouds

    Science.gov (United States)

    Lolli, Simone; Campbell, James R.; Lewis, Jasper R.; Gu, Yu; Welton, Ellsworth J.

    2017-06-01

    We compare, for the first time, the performance of a simplified atmospheric radiative transfer algorithm package, the Corti-Peter (CP) model, versus the more complex Fu-Liou-Gu (FLG) model, for resolving top-of-the-atmosphere radiative forcing characteristics from single-layer cirrus clouds obtained from the NASA Micro-Pulse Lidar Network database in 2010 and 2011 at Singapore and in Greenbelt, Maryland, USA, in 2012. Specifically, CP simplifies calculation of both clear-sky longwave and shortwave radiation through regression analysis applied to radiative calculations, which contributes significantly to differences between the two. The results of the intercomparison show that differences in annual net top-of-the-atmosphere (TOA) cloud radiative forcing can reach 65 %. This is particularly true when land surface temperatures are warmer than 288 K, where the CP regression analysis becomes less accurate. CP proves useful for first-order estimates of TOA cirrus cloud forcing, but may not be suitable for quantitative accuracy, including the absolute sign of cirrus cloud daytime TOA forcing that can readily oscillate around zero globally.

  13. Gauge-theoretic invariants for topological insulators: a bridge between Berry, Wess-Zumino, and Fu-Kane-Mele

    Science.gov (United States)

    Monaco, Domenico; Tauber, Clément

    2017-07-01

    We establish a connection between two recently proposed approaches to the understanding of the geometric origin of the Fu-Kane-Mele invariant FKM\\in Z_2, arising in the context of two-dimensional time-reversal symmetric topological insulators. On the one hand, the Z_2 invariant can be formulated in terms of the Berry connection and the Berry curvature of the Bloch bundle of occupied states over the Brillouin torus. On the other, using techniques from the theory of bundle gerbes, it is possible to provide an expression for FKM containing the square root of the Wess-Zumino amplitude for a certain U( N)-valued field over the Brillouin torus. We link the two formulas by showing directly the equality between the above-mentioned Wess-Zumino amplitude and the Berry phase, as well as between their square roots. An essential tool of independent interest is an equivariant version of the adjoint Polyakov-Wiegmann formula for fields T^2 → U(N), of which we provide a proof employing only basic homotopy theory and circumventing the language of bundle gerbes.

  14. In vivo experimental testing of the FW axial blood pump for left ventricular support in Fu Wai Hospital.

    Science.gov (United States)

    Zhang, Yan; Hu, Sheng-Shou; Zhou, Jian-Ye; Sun, Han-Song; Tang, Yue; Zhang, Hao; Zheng, Zhe; Li, Guo-Rong; Zhu, Xiao-Dong; Gui, Xin-Min

    2009-01-01

    A fully implantable, axial flow blood pump has been developed in Fu Wai Hospital aiming for clinical use. This ventricular assist device (VAD), which was developed after numerous CFD analyses for the flow characteristics of the pump, is 58.5-mm long, 30-mm wide (including DC motor), and weighs 240 g. The pump can deliver 5 L/min for pressures of 100 mm Hg over 8,000 rpm. In this study, short-term hemocompatibility effects of the axial left ventricular assist device (LVAD) (FW blood pump) were evaluated in four healthy sheep. The device was implanted into the left ventricular apex of beating hearts. The outflow graft of each device was anastomosed to the descending aorta. The hemolysis, which was evaluated in vivo by free hemoglobin value, was below 30 mg/dL. Evaluation of serum biochemical data showed that implantation of the FW blood pump in sheep with normal hearts did not impair end organ function. Gross and microscopic sections of kidney, liver, and lung revealed no evidence of microemboli. Performance of the pump in vivo was considered sufficient for a LVAD, although further design improvement is necessary in terms of hemolysis and antithrombosis to improve biocompatibility of the pump.

  15. Graduate Student Attitudes toward Professor Pedagogical Content Knowledge, Transformational Teaching Practices, Student-Professor Engagement in Learning, and Student Deep Learning in Worldwide Business and Education Programs

    Science.gov (United States)

    Economos, Jennifer Lynn

    2013-01-01

    Some professors are expected to remain competitive research scholars, as well as teach, particularly in research-intensive universities. It has been argued that some professors spend too much time on research to obtain institutional incentives or promotion, and not enough time on teaching. Consequently, some adjuncts assume the responsibility for…

  16. EDITORIAL: 65th Birthday of Professor Hauptmann 65th Birthday of Professor Hauptmann

    Science.gov (United States)

    Lucklum, Ralf

    2009-12-01

    The papers in this special feature have been contributed by scientific partners in international research projects and from former PhD students of the Editor-in-Chief of this journal, Professor Dr Peter Hauptmann. The motivation for this feature is the occasion of Peter Hauptmann's 65th birthday on 24 July 2009 and his retirement from his chair at the Otto-von-Guericke-University, Magdeburg, Germany this autumn. Peter graduated in Physics at the Technical University Dresden and received his PhD from the Technical University Leuna-Merseburg in 1973. He habilitated in 1979. With his appointment at the Faculty of Electrical Engineering and Information Technology in 1985 the Chair of Measurement Science extended its profile to the fast growing area of sensors. Peter was one of the very early developers of ultrasonic sensor systems for process monitoring and quality assurance. The working style here was characteristic of all his future activities. He combined his background in theory and experiment on ultrasonic wave propagation and its application to material science with the advantages of rapidly developing capabilities in microelectronics and data processing. The results have meanwhile found their way into products that are now on the market worldwide. Germany's reunification opened the door to the international sensor community and the most challenging sensor research areas. Peter Hauptmann very soon became a well respected colleague and was consequently appointed as member of the Technical Program Committee of the most important sensor conferences, elected member and head of expert groups of research associations and funding organizations, and of course reviewer of many scientific journals. Nowadays Peter Hauptmann can rightly be called one of the key players in the area of sensors. Professor Hauptmann's research interests combine fundamental aspects of the sensor transduction scheme with application issues up to the use of the sensor system in the industrial world

  17. A trio of gamma-ray burst supernovae:. GRB 120729A, GRB 130215A/SN 2013ez, and GRB 130831A/SN 2013fu

    NARCIS (Netherlands)

    Cano, Z.; et al., [Unknown; Hartoog, O.

    2014-01-01

    We present optical and near-infrared (NIR) photometry for three gamma-ray burst supernovae (GRB-SNe): GRB 120729A, GRB 130215A/SN 2013ez, and GRB 130831A/SN 2013fu. For GRB 130215A/SN 2013ez, we also present optical spectroscopy at t − t0 = 16.1 d, which covers rest-frame 3000-6250 Å. Based on Fe ii

  18. Review of dissertation The Association Of Intelligence, Visual-Motor Functioning, And Personality Characteristics With Adaptive Behavior In Individuals With Williams Syndrome by Juhsin Trista Fu

    Directory of Open Access Journals (Sweden)

    Florova N.B.

    2015-06-01

    Full Text Available Juhsin Trista Fu (Taiwan is an American clinical psychologist, doctor of philosophy (PhD, on the national register of health professionals of United States National Provider Identifiers (NPI Registry. The proposed material gives a systematic description of the dynamics of specific behavioral construct in adults in situation of genetic anomalies. The author regards this condition as a volatile state which to a certain extent responds to interventions.

  19. Crowdfund your City: Empirische Studie zum Einsatz des Crowdfundings als Finanzierungsinstrument für Städte, Länder und Kommunen

    OpenAIRE

    Kunz, Michael; Ruth, Lukas; Bretschneider, Ulrich

    2016-01-01

    Crowdfunding (CF) stellt zunehmend eine innovative Finanzierungsmöglichkeit dar, bei der über eine unbestimmte Gruppe finanzielle Mittel für bestimmte Projekte eingesammelt werden können. In den vergangenen Jahren erfreute sich dieses Finanzierungsinstrument aufgrund einer sich wandelnden Wahrnehmung, einer verstärkten Nutzung des Internets (Web 2.0) sowie einer stetig steigenden mobilen Konnektivität von Personen einer wachsenden Beliebtheit, vor allem zur Finanzierung von Projekten in...

  20. Synthesis and biological evaluation of novel podophyllotoxin-NSAIDs conjugates as multifunctional anti-MDR agents against resistant human hepatocellular carcinoma Bel-7402/5-FU cells.

    Science.gov (United States)

    Zhang, Lei; Liu, Lai; Zheng, Chengyue; Wang, Yang; Nie, Xuqiang; Shi, Dabin; Chen, Yongzheng; Wei, Gang; Wang, Jing

    2017-05-05

    Currently, multi-drug resistance (MDR) to chemotherapy agents is a major hindrance to the treatment of hepatocellular carcinoma. Development of novel antineoplastic drug with anti-MDR activity is an effectively way to overcome cancer resistance. In present study, novel podophyllotoxin-NSAIDs conjugates were synthesized, and their antiproliferative activities were evaluated in vitro. The most potent conjugate, A1, displayed selective cytotoxicity against resistant Bel-7402/5-FU cells with an IC50 value of 0.065 ± 0.016 μM and a lower resistant factor value of 0.32. In addition, all conjugate molecules efficiently triggered cell cycle arrest at S + G2 phase, induced apoptosis, disrupted the microtubule network and showed antimigratory activity in Bel-7402/5-FU cells. Finally, three conjugates regulated the levels of cell cycle arrest-, apoptosis-, migratory-, inflammatory- and MDR-related proteins, as well as three signaling in Bel-7402/5-FU cells by some but not all similar molecular mechanisms. Together, these findings highlighted the cytotoxic and multifunctional anti-MDR properties of podophyllotoxin-NSAIDs conjugates for the first time, which may be promising candidates for intervention of resistant hepatocellular carcinoma. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  1. Fatores associados a patologias de pregas vocais em professores

    Directory of Open Access Journals (Sweden)

    Carla Lima de Souza

    2011-10-01

    Full Text Available OBJETIVO: Analisar fatores associados à prevalência do diagnóstico médico referido de patologias das pregas vocais em professores. MÉTODOS: Estudo epidemiológico transversal, censitário, com 4.495 professores da rede pública municipal de ensino elementar e fundamental de Salvador, BA, de março a abril de 2006. A variável dependente foi o diagnóstico médico referido de patologias das pregas vocais e as independentes, características sociodemográficas, atividade profissional, organização do trabalho/relações interpessoais, características físicas do ambiente de trabalho, freqüência de transtornos mentais comuns, medida pelo Self-Reporting Questionnaire-20 (SRQ-20 >7 e condições de saúde geral. Foram aplicadas técnicas de análise estatística descritiva, bivariada e regressão logística múltipla. RESULTADOS: A prevalência de diagnóstico médico referido de patologias das pregas vocais foi de 18,9%. Na análise de regressão logística, as variáveis que permaneceram associadas ao diagnóstico médico de patologia das pregas vocais foram: sexo feminino, trabalhar como professor por mais de sete anos, uso intensivo da voz, referir mais de cinco características desfavoráveis do ambiente físico de trabalho, uma ou mais doenças do trato respiratório, perda auditiva e apresentar transtornos mentais comuns. CONCLUSÕES: A presença de patologias das pregas vocais referidas associou-se a fatores que indicam a necessidade de ações de promoção da saúde vocal do professor e modificações na organização e estrutura do trabalho docente.

  2. Professor Borje Kullenberg (1906-1991): Biography and bibliography

    Digital Repository Service at National Institute of Oceanography (India)

    Sengupta, R.; Eriksson, G.

    was undisturbed, the “vacuum principle” was omitted and the “piston principle” and “free-fall principle”, were combined, utilising the enormous hydrostatic pressures at great ocean depths. Thus the piston corer, capable of collecting sediment cores up to 20 m... in the artillery he had to criss-cross Sweden many times on skis on important missions. No wonder he had a strong physique throughout his life! After the cessation of hostilities, all the flaws of the piston corer were rectified and a cruise 2 Professor Biirje...

  3. PROFESSOR DR. ION PIŞOTA (1925 – 2008)

    OpenAIRE

    Liliana ZAHARIA

    2009-01-01

    Professor Ion Pişota was born on June 6, 1925, in Hrupiştea, a small settlement in Greek Macedonia, from where he and his family came to Romania in 1927, where he got Romanian citizenship. Between 1941 and 1945, he attended the Tulcea Boys High School and later on, in 1947 he entered the Faculty of Geology – Geography at the University of Bucharest, where he continued to excel until 1951, when he graduated. In the fall of 1950, he took up a tutor position in the field of Hydrolgy at the same ...

  4. The Forgetful Professor and the Space Biology Adventure

    Science.gov (United States)

    Massa, Gioia D.; Jones, Wanda; Munoz, Angela; Santora, Joshua

    2014-01-01

    This video was created as one of the products of the 2013 ISS Faculty Fellows Summer Program. Our High School science teacher faculty fellows developed this video as an elementary/middle school education component. The video shows a forgetful professor who is trying to remember something, and along the journey she learns more about the space station, space station related plant science, and the Kennedy Space Center. She learns about the Veggie hardware, LED lighting for plant growth, the rotating garden concept, and generally about space exploration and the space station. Lastly she learns about the space shuttle Atlantis.

  5. [Preliminary study on Professor SUN Liu-he's academic thought].

    Science.gov (United States)

    Sun, Guo-Sheng; Zhang, Jing-Feng

    2005-07-01

    Professor SUN Liu-he has been engaged in scientific research, clinical and teaching works for tens years and he is a meticulous scholar with great learning, rich clinical experience and great theoretical attainments. In clinical practice of many years, he summarizes and develops Kangai Plaster, Kangai Fushui Plaster, Ai tong Ling Plaster, and so on for acupoint sticking to treat tumors, and establishes Nu-needle hot-reinforcing method and Ti-Yun reducing method, enriching contents of needling methods, and he is good at application of specific points, established points and channel acupoints to treat refractory diseases with good results.

  6. Comunidades em processos formativos de professores de ciências

    OpenAIRE

    Willian Rubira da Silva; Valmir Heckler

    2017-01-01

    Apresentamos compreensões sobre as diferentes concepções de comunidade dentro do contexto da formação de professores de Ciências. Termos relacionados a comunidades no contexto de ensino e aprendizagem vem se tornando genéricos, dificultando compreensões de trabalhos da área no Brasil. Visualizamos a necessidade de significar concepções do termo em questão no contexto da sociologia e psicologia para então avançar nas compreensões mais abrangentes dentro da educação. Ampliamos o estudo com uma ...

  7. A biographical note on Marcel Proust's Professor Cottard.

    Science.gov (United States)

    Pearn, John; Gardner-Thorpe, Christopher

    2003-05-01

    A medical practitioner, Professor Cottard, features in Marcel Proust's A la recherche du temps perdu, which has been described as one of the supreme achievements of world literature. Proust modelled the character of Cottard on the real-life Parisian neurologist and psychiatrist Dr Jules Cotard (1840-1889). Marcel Proust's father, Dr Adrien Proust, was an eminent Parisian surgeon and a contemporary of Cotard. A review of the biographical literature (in French) relating to Dr Jules Cotard and an analysis of his published work (in English and French) have revealed a striking parallelism between the lives of the fictional Cottard and Jules Cotard.

  8. Taklimakan dust aerosol radiative heating derived from CALIPSO observations using the Fu-Liou radiation model with CERES constraints

    Directory of Open Access Journals (Sweden)

    J. Huang

    2009-06-01

    Full Text Available The dust aerosol radiative forcing and heating rate over the Taklimakan Desert in Northwestern China in July 2006 are estimated using the Fu-Liou radiative transfer model along with satellite observations. The vertical distributions of the dust aerosol extinction coefficient are derived from the CALIPSO (Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations lidar measurements. The CERES (Cloud and the Earth's Energy Budget Scanner measurements of reflected solar radiation are used to constrain the dust aerosol type in the radiative transfer model, which determines the dust aerosol single-scattering albedo and asymmetry factor as well as the aerosol optical properties' spectral dependencies. We find that the dust aerosols have a significant impact on the radiative energy budget over the Taklimakan desert. In the atmospheres containing light, moderate and heavy dust layers, the dust aerosols heat the atmosphere (daily mean by up to 1, 2, and 3 K day−1, respectively. The maximum daily mean radiative heating rate reaches 5.5 K day−1 at 5 km on 29 July. The averaged daily mean net radiative effect of the dust are 44.4, −41.9, and 86.3 W m−2, respectively, at the top of the atmosphere (TOA, surface, and in the atmosphere. Among these effects about two thirds of the warming effect at the TOA is related to the longwave radiation, while about 90% of the atmospheric warming is contributed by the solar radiation. At the surface, about one third of the dust solar radiative cooling effect is compensated by its longwave warming effect. The large modifications of radiative energy budget by the dust aerosols over Taklimakan Desert should have important implications for the atmospheric circulation and regional climate, topics for future investigations.

  9. Metabolomic analysis of anti-hypoxia and anti-anxiety effects of Fu Fang Jin Jing Oral Liquid.

    Directory of Open Access Journals (Sweden)

    Xia Liu

    Full Text Available BACKGROUND: Herba Rhodiolae is a traditional Chinese medicine used by the Tibetan people for treating hypoxia related diseases such as anxiety. Based on the previous work, we developed and patented an anti-anxiety herbal formula Fu Fang Jin Jing Oral Liquid (FJJOL with Herba Rhodiolae as a chief ingredient. In this study, the anti-hypoxia and anti-anxiety effects of FJJOL in a high altitude forced-swimming mouse model with anxiety symptoms will be elucidated by NMR-based metabolomics. METHODS: In our experiments, the mice were divided randomly into four groups as flatland group, high altitude saline-treated group, high altitude FJJOL-treated group, and high altitude diazepam-treated group. To cause anxiety effects and hypoxic defects, a combination use of oxygen level decreasing (hypobaric cabin and oxygen consumption increasing (exhaustive swimming were applied to mice. After a three-day experimental handling, aqueous metabolites of mouse brain tissues were extracted and then subjected to NMR analysis. The therapeutic effects of FJJOL on the hypobaric hypoxia mice with anxiety symptoms were verified. RESULTS: Upon hypoxic exposure, both energy metabolism defects and disorders of functional metabolites in brain tissues of mice were observed. PCA, PLS-DA and OPLS-DA scatter plots revealed a clear group clustering for metabolic profiles in the hypoxia versus normoxia samples. After a three-day treatment with FJJOL, significant rescue effects on energy metabolism were detected, and levels of ATP, fumarate, malate and lactate in brain tissues of hypoxic mice recovered. Meanwhile, FJJOL also up-regulated the neurotransmitter GABA, and the improvement of anxiety symptoms was highly related to this effect. CONCLUSIONS: FJJOL ameliorated hypobaric hypoxia effects by regulating energy metabolism, choline metabolism, and improving the symptoms of anxiety. The anti-anxiety therapeutic effects of FJJOL were comparable to the conventional anti-anxiety drug

  10. A phase II experience with neoadjuvant irinotecan (CPT-11, 5-fluorouracil (5-FU and leucovorin (LV for colorectal liver metastases

    Directory of Open Access Journals (Sweden)

    Bigam David

    2009-05-01

    Full Text Available Abstract Background Chemotherapy may improve survival in patients undergoing resection of colorectal liver metastases (CLM. Neoadjuvant chemotherapy may help identify patients with occult extrahepatic disease (averting unnecessary metastasectomy, and it provides in vivo chemosensitivity data. Methods A phase II trial was initiated in which patients with resectable CLM received CPT-11, 5-FU and LV for 12 weeks. Metastasectomy was performed unless extrahepatic disease appeared. Postoperatively, patients with stable or responsive disease received the same regimen for 12 weeks. Patients with progressive disease received either second-line chemotherapy or best supportive care. The primary endpoint was disease-free survival (DFS; secondary endpoints included overall survival (OS and safety. Results 35 patients were accrued. During preoperative chemotherapy, 16 patients (46% had grade 3/4 toxicities. Resection was not possible in 5 patients. One patient died of arrhythmia following surgery, and 1 patient had transient liver failure. During the postoperative treatment phase, 12 patients (55% had grade 3/4 toxicities. Deep venous thrombosis (DVT occurred in 11 patients (34% at various times during treatment. Of those who underwent resection, median DFS was 23.0 mo. and median OS has not been reached. The overall survival from time of diagnosis of liver metastases was 51.6 mo for the entire cohort. Conclusion A short course of chemotherapy prior to hepatic metastasectomy may serve to select candidates best suited for resection and it may also direct postoperative systemic treatment. Given the significant incidence of DVT, alternative systemic neoadjuvant regimens should be investigated, particularly those that avoid the use of a central venous line. Trial Registration ClinicalTrials.gov NCT00168155.

  11. EFECTO DEL GRITO COMO UN RECURSO ERGOGÉNICO PSICOLÓGICO EN PRACTICANTES DE KUNG FU

    Directory of Open Access Journals (Sweden)

    Juan Diego Zamora Salas

    2002-12-01

    Full Text Available El presente estudio analizó el efecto del grito como mecanismo inhibidor de sensaciones como el dolor y la fatiga enpracticantes de Kung Fu, utilizando una prueba de push ups. Se formaron tres grupos de forma aleatoria,cada uno conformado por n= 10, cuyas edades estaban comprendidas entre los 15 y 30 años. Los sujetos del Grupo Experimental sin grito y Grupo Experimental con grito, les correspondía realizar las prácticas depush ups aplicando los tratamientos correspondientes durante cinco semanas; mientras que los sujetos delgrupo control no realizaban éstas prácticas durante el período establecido, sólo les correspondía el pre-testy post-test. A los valores recolectados durante las pruebas se les aplicó una Anova 3 x 2 y un análisis posthocde la interacción mostrando la existencia de una diferencia significativa entre el pre-test y el post-testtanto en el grupo que aplicó el grito personal como en el grupo que no lo aplicó, lo cual no se manifestóentre el pre-test y post-test del grupo control. Al comparar los datos obtenidos del grupo que utilizó el gritopersonal con respecto al grupo que no utilizó el grito como tratamiento, se encontró una diferenciasignificativa entre ambos métodos. Con el estudio se concluyó que el grito en combinación con el ejerciciofísico permite observar incrementos significativos en la cantidad de repeticiones de un ejercicio de fuerzapara el tren superior como son las push ups, luego de cinco semanas de tratamiento.

  12. Emissions of particle-phase polycyclic aromatic hydrocarbons (PAHs) in the Fu Gui-shan Tunnel of Nanjing, China

    Science.gov (United States)

    Chen, Fei; Hu, Wei; Zhong, Qin

    2013-04-01

    Real-world vehicle emission factors for PM10 (particulate matter with aerodynamic diameter smaller than 10 μm) and particle-phase polycyclic aromatic hydrocarbons (PAHs) from mixed vehicles were quantified in the Fu Gui-shan Tunnel of Nanjing during summer and winter of 2010. Concentrations of PM10 and sixteen particle phase polycyclic aromatic hydrocarbons (PAHs) in the entrance and exit of the tunnel were studied. The results showed that the four most abundant particular phase polycyclic aromatic hydrocarbons (PAHs) of motor vehicle were benzo[ghi]perylene, benzo[k]fluoranthene, benz[a]anthracene and benzo[a]pyrene. The emission factors for PM10 and particle-phase PAHs were 687 mg veh- 1 km- 1 and 18.853 mg veh- 1 km- 1 in summer, 714 mg veh- 1 km- 1 and 20.374 mg veh- 1 km- 1 in winter. Higher particle-phase PAH emission factors were found to be associated with a high proportion of diesel-fueled vehicles (DV). The estimated PM10 emission factor of gasoline-fueled vehicles (GV) was 513 mg veh- 1 km- 1 and the value for DV was 914 mg veh- 1 km- 1, while EFDV of particulate PAH (31.290 mg veh- 1 km- 1) was nearly 4 times higher than EFGV (9.310 mg veh- 1 km- 1). The five highest emission factors of diesel-fueled vehicles (DV) were benzo[ghi]perylene, benzo[k]fluoranthene, Indeno[1,2,3-cd]pyrene, benz[a]anthracene and benzo[a]pyrene, which was similarly found in the gasoline-fueled vehicles (GV). The sum of these five emission factors accounted for ~ 69% of the total particle-phase PAH of DV and ~ 67% of GV.

  13. Transactional sex and sexual harassment between professors and students at an urban university in Benin.

    Science.gov (United States)

    Eller, Amanda

    2016-07-01

    This paper adds to discussion of transactional sex relationships in Africa by examining the distinction between transactional sex and sexual harassment in the context of professor-student relationships and their inherent power dynamics. By exploring the ways in which female university students in urban Benin toe the line between empowered agent and victim, I show how the power differential between professor and student obstructs the professor's ability to objectively determine consent, and examine why, in spite of this differential, male professors are frequently perceived as the victims of these relationships. Ethnographic data were gathered through participant observation on a public university campus in Benin and in-depth interviews and focus groups with 34 students and 5 professors from that university. Findings suggest that the problem of sexual harassment on campus will be difficult to address so long as transactional sex relationships between professors and students are permitted to continue.

  14. [Professor as a facilitating agent of the teaching learning process: perspective of the nursing student].

    Science.gov (United States)

    Semim, Gabriela Maschio; Souza, Maria Conceição Bernardo de Mello; Corrêa, Adriana Kátia

    2009-09-01

    This study aimed at analyzing how the undergraduate student perceives professor's performance in the teaching-learning process, in courses using the critical pedagogy and dialogical competence approach, in the Nursing Bachelor's Program, from 2005 to 2006. An instrument for the assessment of the professors performance was used and answers from 142 students were analyzed. Through thematic analysis, the following meaning units were outlined approaching the teaching-learning process, professor/student relationship and evaluation. For most students, professors who stimulate the critical-reflexive process, coherent with the problem-solving methodology, facilitate the teaching-learning process. For others, this process is facilitated when the professor is more demanding in contrast with the problem-solving approach. The professor-student relationship was facilitated by the establishment of bonds. Students did few comments about evaluation, indicating the need of a formative evaluation, which is a work in progress.

  15. Phase II Study of Capecitabine in Substitution of 5-FU in the Chemoradiotherapy Regimen for Patients with Localized Squamous Cell Carcinoma of the Anal Canal.

    Science.gov (United States)

    Oliveira, Suilane Coelho Ribeiro; Moniz, Camila Motta Venchiarutti; Riechelmann, Rachel; Alex, Alexandra Kichfy; Braghirolli, Maria Ignez; Bariani, Giovanni; Nahas, Caio; Hoff, Paulo Marcelo Gehm

    2016-03-01

    This was a phase II study of capecitabine in substitution of 5-fluorouracil (5-FU) in the chemoradiotherapy regimen for patients with localized squamous cell carcinoma of the anal canal. Combined chemoradiation with infusional 5-FU and mitomycin is the standard treatment for localized squamous cell carcinoma (SCC) of the anal canal. Capecitabine is an oral fluoropirimidine that has been shown to be equally effective to 5-FU in many solid tumors. However, the efficacy of the substitution of 5-FU for capecitabine in anal SCC needs confirmation. Patients with SCC of anal cancer T2-4N0M0 or T (any) N1-3M0, with good performance status and normal blood and renal function, were treated with capecitabine 825 mg/m(2) bid during radiotherapy associated with a single dose of mitomycin 15 mg/m(2) on day 1. The primary objective was local control rate at 6 months determined by clinical examination and radiological assessment. Sample size was calculated using the Fleming single-stage design. From November 2010 to February 2014, N = 51 patients were initially included; however, 43 patients were assessed. Seventeen patients (39.5%) were stage II, 11 patients (25.6%) stage IIIA, and 15 patients (34.9%) stage IIIB. Four patients (9.3%) were HIV positive. With a median follow-up of 23.1 months (range 4 to 44.4 months), 3 patients (7%) presented partial response, 37 (86%) had complete response, and 3 patients developed progression of the disease (7%) at 6 months. The colostomy rate was 18.6%. It was observed a locoregional control of 86% in 6 months (CI 95% 0.72-0.94). The main grade 3-4 toxicities were grade 3 radiodermitis in 10 patients (23.2%), grade 3 lymphopenia in 5 patients (11.6%), and grade 3 neutropenia in 2 patients (6.9%). One HIV-positive patient had septic shock, pneumonia, herpetic encephalitis, atrial fibrillation, and macrophage activation syndrome. Capecitabine can safely substitute infusional 5-FU in the standard chemoradiation regimen for SCC of the anal cancer

  16. Surdez, políticas inclusivas e professores turistas

    Directory of Open Access Journals (Sweden)

    Fernanda de Camargo Machado

    2017-02-01

    Full Text Available Este artigo provém de uma pesquisa que teve como foco as políticas públicas com acento na formação de professores de surdos no regime inclusivo. A analítica aproxima-se no arcabouço teórico-metodológico dos Estudos da Governamentalidade, propostos por Michel Foucault, tomando as noções de "dispositivo" e "governamentalidade" como alavancas para a compreensão do papel e atuação do docente de surdos nas políticas inclusivas. Os documentos selecionados para a investigação são materiais/cartilhas/coleções destinadas aos professores da Educação Infantil e Ensino Fundamental das escolas comuns, no sentido de orientá-los quanto à inclusão educacional de surdos. Este empreendimento analítico apontou a utilização de técnicas que produzem no docente de surdos um perfil profissional conveniente aos anseios neoliberais, de controle e produtividade.

  17. Dificuldades no relacionamento professor/aluno: um desafio a superar

    Directory of Open Access Journals (Sweden)

    Fábia Moreira Squarça Cabral

    2004-12-01

    Full Text Available O relacionamento professor - aluno é um tema que vem sendo investigado, através de diferentes estratégias metodológicas. Este trabalho trata a questão a partir da visão dos atores que participam do processo de ensino e aprendizagem, tendo por base professores e alunos de uma 8ª Série, de uma escola estadual da região de Londrina, Paraná, que responderam a um questionário, elaborado com questões abertas. Um estudo comparativo entre as informações fornecidas pelos dois grupos de participantes elucida momentos de tensão e de entrosamento entre estes personagens que constroem e reconstroem vivências e experiências capazes de expor valores e modos de vida. A luta pela sobrevivência de objetos alvo da escola, a aprendizagem e o conhecimento, é de interesse de todos, que consciente ou inconscientemente, participam do processo em busca de um caminho harmônico de convivência e crescimento.

  18. Professor Dorothy A.E. Garrod: "Small, Dark, and Alive!"

    Directory of Open Access Journals (Sweden)

    Pamela Jane Smith

    1997-05-01

    Full Text Available In 1939, Dorothy Garrod became the first woman Professor in either Cambridge or Oxford. Garrod at the time was Director of Studies at Newnham College, Cambridge University and had been in charge of excava­tions in Gibraltar, Western Judaea, Southern Kurdistan and Mount Carmel for which she is now renowned. Trained by Marett at Oxford and Abbe Henri Breuil in France, she was one of our finest archaeologists. By 1939, Garrod had unearthed the well-preserved skull of 'Abel', a Neanderthal child, in Gibraltar, discovered and named the Natufian culture while excavating Shukba near Jerusalem, directed the long term, large scale excavations at Mount Carmel and traveled with Bruce Howe as her assistant to explore Bacho Kiro in Bulgaria. Once elected Professor, she became instrumental in establishing Archaeology and Anthropology as a full degree course and influential in Cambridge's decision to admit women to full membership in 1948. After retirement, she continued excavating in Lebanon and France. Here, with her close friend Suzanen Cassou de Saint Mathurin, she discovered the superb Magdalenian sculptured frieze at Angles-sur-l'Anglin.

  19. Entrevista com o professor João Rua

    Directory of Open Access Journals (Sweden)

    Demian Garcia Castro

    2014-07-01

    Full Text Available Em um final de tarde na PUC-RJ, logo após mais uma de suas aulas de mestrado, o Prof. João Rua recebeu a equipe da Revista Giramundo para uma entrevista. Com experiência em diferentes segmentos de ensino no CAP-UFRJ, na UERJ e na própria PUC-RJ, entre outras instituições, João Rua igualmente diversificou muito sua produção como pesquisador, passando do Ensino de Geografia à Geografia Agrária e, depois, às questões ambientais, sem nunca deixar de lado uma visão política e reflexiva sobre os temas que abordou. Por essa versatilidade, pela personalidade extremamente comunicativa e por outras qualidades, Rua tornou-se um referencial como professor e intelectual para gerações de ex-alunos influenciados por suas práticas e ensinamentos. Registrar um pouco mais desse arcabouço teórico e prático foi um dos objetivos da entrevista, assim como o de prestar homenagem a esse professor muito querido por tantas pessoas de dentro e de fora de nosso campo de conhecimento.

  20. Burnout Syndrome and Self-Efficacy Beliefs in Professors

    Directory of Open Access Journals (Sweden)

    Arlington Antonio García Padilla

    2017-10-01

    Full Text Available The presence of the Burnout syndrome in professors may be regarded as a deterioration of their mental health with negative impacts on their job performance. It is known that teachers develop different activities in the areas of teaching, outreach and research. This study aims to analyze the relationship between the Burnout syndrome and self-efficacy beliefs and the academic performance in professors of the psychology and dentistry programs at a private university in the city of Barranquilla. This study is empirical and analytical with a descriptive-correlational design. The study population consisted of 93 teachers of the psychology and dentistry programs. To choose the sample, a non-probabilistic sample was used according to the inclusion and exclusion criteria that allowed selecting a total of 36 teachers who met the criteria for the study. The instruments that were used in this study was the Maslach Burnout Inventory (MBI, 1981 adapted by Seisdedos (1997, and the Teachers’ Self-Efficacy Beliefs of Tschannen-Moran and Woolfolk (2001 adapted by Covarrubias and Mendoza (2016. According to the results, it was observed that there is no significant relationship between Burnout, Self-efficacy Belief and the academic performance.

  1. Tomorrow's Professor, Preparing for an Academic/Research Career

    Science.gov (United States)

    Reis, R. M.

    1998-12-01

    Richard M. Reis, author of Tomorrow's Professor: Preparing for Academic Careers in Science and Engineering, and a former executive officer of the Astronomical Society of the Pacific, will discuss the essential elements in preparing for, finding, and succeeding at academic careers in today's higher education environment. He will begin with a no-hold-barred look at the academic enterprise and the important ways it differs for all other institutions in society. The unique nature engineering and science - with a particular emphasis on astronomy and astrophysics - in higher education and the special problems facing new professors in these fields will be looked at next. Dr. Reis will then describe a powerful preparation strategy to make graduate students and postdocs competitive for academic positions while maintaining their options for worthwhile careers in government and industry. He will then explain how to get the offer you want and the start-up package you need to ensure success in your first critical years on the job. Finally, Dr. Reis will summarize essential insights from experienced faculty in all areas of science and engineering on how to develop a rewarding academic career and a quality of life that is both balanced and fulfilling. Plenty of time will be set aside for active interaction and discussion.

  2. O papel do professor junto ao aluno com Altas Habilidades

    Directory of Open Access Journals (Sweden)

    Andréia Jaqueline Devalle Rech

    2012-03-01

    Full Text Available .Quando se discute a Educação Especial é comum, num primeiro momento, lembrar do aluno que compõe o especial na Educação como aquele com deficiência mental, auditiva, visual ou física. No entanto, assim como essas crianças, também os alunos com altas habilidades necessitam de um atendimento especializado, pois ele também é um sujeito da Educação Especial. Nesse sentido, este artigo apresenta a definição de altas habilidades, baseada na teoria de um pesquisador norte-americano e, como foco principal algumas questões que envolvem o professor de forma mais direta com o aluno com altas habilidades em sala de aula. Entre elas estão: questões sobre a aprendizagem escolar desses alunos, bem como os fatores que fazem parte desse processo, estratégias de ensino e a importância da identificação dos alunos com altas habilidades.Palavras-chave: Educação Especial. Professor. Aluno com Altas Habilidades

  3. Professor Adler-Nissen i Radio 27syv

    DEFF Research Database (Denmark)

    2017-01-01

    Professor Adler-Nissen var fredag den 9. juni i radio 24syv (program 24syv Morgen) i forlængelse af den britiske valg. Her blev Adler-Nissen blandet andet spurgt ind til, hvilken betydning valget vil have for de kommende Brexit-forhandlinger. Adler-Nissen vurderede, at en udskydelse af forhandlin......Professor Adler-Nissen var fredag den 9. juni i radio 24syv (program 24syv Morgen) i forlængelse af den britiske valg. Her blev Adler-Nissen blandet andet spurgt ind til, hvilken betydning valget vil have for de kommende Brexit-forhandlinger. Adler-Nissen vurderede, at en udskydelse af...... forhandlingerne er et muligt scenario, da Theresa May først skal havde samlet en koalitionsregering. I følge Adler-Nissen, vil en sådan koalitionsregering også kunne have den indvirkning, at forhandlingerne vil lede til et blødere Brexit end først udmeldt af May, da der nu er behov for at tage højde til flere...... partiers holdning til Brexit....

  4. The art of science: interview with Professor John Archibald Wheeler

    CERN Document Server

    Bičák, Jiři

    2011-01-01

    During the conference on the methods of differential geometry in physics in Warsaw in June 1976, Professor Wheeler gave an interview for the Czechoslovak Journal of Physics A. After Professor Wheeler authorized the English version in January 1977, the Czech translation was published in \\v{C}eskoslovensk\\'y \\v{c}asopis pro fyziku A (1978) and soon afterwards the Polish translation appeared in Postepy fizyky. After John Wheeler's recent death it occurred to me that it would now be appropriate to publish the original interview from 1976 so that it would not be lost to English readers; and so, despite being more than 30 years old, the interview appeared in the special issue on quantum gravity of "General Relativity and Gravitation" dedicated to the memory of J. A. Wheeler. John Wheeler would now surely add more about black holes in nuclei of galaxies, not mentioning just Cygnus X-1, when discussing cosmology he would undoubtedly address the problem of dark energy etc. However, in the conversation about Einstein a...

  5. Homage to Professor Hans-Åke Gustafsson

    CERN Multimedia

    2010-01-01

    It was with deep sadness that we learned of the death of Professor Hans-Åke Gustafsson, an internationally recognized scientist, beloved colleague and friend. He passed away on Wednesday January 13th at the Lund University Hospital, surrounded by his loved ones, after a short battle against cancer. This is a great loss for all of us in ALICE and the whole heavy ion community. Hans-Åke, Professor at Lund University, was one of the pioneers of heavy ion physics with relativistic beams since its very beginning. He started his research at CERN, as a fellow at the ISOLDE ion beam facility, and immediately after, in the early 1980 joined the Plastic Ball collaboration at the Bevalac. One of the seminal papers of the field on the discovery of collective flow in relativistic nuclear collisions, co-authored by Hans-Åke, Hans Gutbrod and colleagues, stems from this period. From that point on he was always at the forefront of research with relativistic nuclear beams, being for three de...

  6. [Combination therapy of continuous venous infusion (CVI) of 5-FU and low dose consecutive cisplatin (CDDP), and the new oral anti-cancer drug S-1 for advanced gastro-intestinal cancer].

    Science.gov (United States)

    Shirasaka, T; Aiba, K; Araki, H; Suzuki, M; Terashima, M; Mikami, Y

    1999-03-01

    Highly effective treatment is required for patients with advanced GI cancer. Returning to the starting point for reconsideration of cancer chemotherapy, with the aim of attaining a therapy (self rescuing concept: SRC) with more potential efficacy and less toxicity than current therapy, we report two kinds of chemotherapy in the present paper. They were set up preclinically using the theory of 5-FU biochemical modulation, and demonstrated their usefulness in clinical practice. S-1 is a newly developed oral anti-cancer drug which is a combination of Tegafur (FT), a prodrug of 5-FU and two modulators (CDHP, an inhibitor of 5-FU degradation and Oxo, a selective inhibitor GI toxicity by 5-FU) at a molar ratio of 1:0.4:1. In combination with CDHP, 5-FU gradually released from FT remained longer in plasma, and consequently had high anti-tumor activity, while the combined Oxo significantly suppressed GI toxicity due to 5-FU. The response rate to S-1 of stomach cancer in a phase II study was 46.5% (60/129). Toxicity at more than G3 was less than 10%. In the combination therapy employing 5-FU by CVI (5-FU: 250-350 mg/body for 24 h, 4-6 wks) and low dose consecutive CDDP, CDDP acts mainly as a modulator of 5-FU (to increase 5-FU sensitivity for tumor by inhibition of intracellular Met incorporation). For this purpose, it was found that daily consecutive administration is required, even at low dose of CDDP (3-5 mg/body/day for 5 days). A high response rate (40-60%) was obtained for advanced GI cancer. Toxicity at more than G3 was less than 10%. On the other hand, the possibility has been suggested that so far as 5-FU is concerned, CVI every other day (500-750 mg/body/day for 3 days) is more favorable than long term CVI, with regard to decreasing GI and myelotoxicities based upon the difference in generation time between normal cell (GI mucous membrane and stem cell) and tumor cell cycles. The possibility is suggested that the above-mentioned chemotherapy can become a standard

  7. Professores homossexuais: suas vivências frente à comunidade escolar

    Directory of Open Access Journals (Sweden)

    Luana Molina

    2012-10-01

    Full Text Available Este trabalho tem como objetivo apresentar uma discussão referente à problemática da vivência diária do professor/professora homossexual frente à instituição escolar, cujo pressuposto inicial parte da premissa que estes professores sofreram e vem sofrendo, algum tipo de preconceito devido sua orientação sexual. No desenvolvimento, partimos para uma abordagem qualitativa e fundamentando-se na análise de discurso, ou seja, conhecendo as experiências de professores e professoras por meio de suas narrativas. Para isso foram entrevistados dois professores gays e uma professora lésbica, todos com ensino superior, que atuam ou atuaram no Ensino Fundamental II e no Ensino Médio. Nossa estratégia metodológica acontece em duas situações: A primeira, por meio de um questionário prévio composto de dez questões de identificação pessoal no intuito de traçar um perfil dos entrevistados. No segundo momento, entrevistas semi – estruturadas, com perguntas que focaram mais especificamente a percepção dos professores/professoras sobre a homofobia na escola. Nosso resultado é composto por relatos onde pudemos identificar a escola como um ambiente que reflete o sexismo que perpassa toda a sociedade, reproduzindo com frequência, as estruturas sociais, reforçando os preconceitos e privilégios de um sexo sobre o outro. Desta forma, percebemos que o heterossexismo está tão arraigado na cultura, que se torna invisível em muitas de suas atitudes quase sutis, como por exemplo, em brincadeiras e piadas. O universo escolar reproduz os preconceitos da sociedade e, na tentativa de evitar o convívio dos alunos heterossexuais, com pessoas homossexuais, faz da homossexualidade o maior alvo da discriminação. Concluímos, portanto, que as desigualdades entre os sexos e a marginalização dos homossexuais acabam gerando vítimas de uma sociedade inacabada, de repressão, opressão e desinformação. Por fim, está sociedade esta em constante

  8. Lifestyle and physical activity of the physical education professor

    Directory of Open Access Journals (Sweden)

    Maria de Fátima M. Maia

    2003-06-01

    Full Text Available The purpose of this study was: 1 to identify the physical activity habits in daily life of the professors at the Physical Education Department of UNIMONTES; 2 to verify the lifestyles of these individuals in terms of five well-being-related items (nutrition, physical activity, preventative behavior, social relationships, and stress control. Twenty Physical Education professors (5 women and 15 men, 27 to 53 years of age were evaluated. Three instruments were employed to obtain the required information: 1 PAR-Q, 2 Physical Activity Survey, and 3 Life Style Profi le using the Well Being Pentagram. It was verifi ed that 74% of the males were apparently fi t enough to initiate a physical exercise program. On the other hand, this number decreased to 40% in the female group. Concerning the physical activity questionnaire, 75% of the male group were active or very active, and only 40% of the female group were active. Regarding the lifestyle profi les (Well Being Pentagram, females did not report desirable healthy behavior, since their mean score was 1.4 points. In the male group, the mean score was 2.0 points, which indicates a healthy lifestyle, as well as an attitude more favorable to preventative health. We concluded that women require more attention than men, relating to the aspects mentioned above, and that men should not forget to keep on having healthy habits. RESUMO Este estudo teve por objetivos: a identifi car os hábitos de atividades físicas no cotidiano dos professores de Educação Física da UNIMONTES; b verifi car o perfi l do estilo de vida considerando cinco fatores (nutrição, atividade física, comportamento preventivo, relacionamento social e controle do stress individuais relacionados ao bem-estar. Foram avaliados 20 (vinte professores de Educação Física, sendo cinco mulheres (25% e quinze homens (75%, na faixa etária de 27 a 53 anos de idade. Para coleta das informações, utilizou-se três instrumentos: a PAR-Q; Physical

  9. Concurrent hyperfractionated accelerated radiotherapy with 5-FU and once weekly cisplatin in locally advanced head and neck cancer. The 10-year results of a prospective phase II trial

    Energy Technology Data Exchange (ETDEWEB)

    Budach, V.; Boehmer, D.; Badakhshi, H.; Jahn, U.; Stromberger, C. [Campus Virchow Klinikum, Charite Universitaetsmedizin Berlin, Department for Radiooncology, Clinic for Radiooncology, Berlin (Germany); Becker, E.T. [Charite Universitaetsmedizin, Department of Otorhinolaryngology, Berlin (Germany); Wernecke, K.D. [Sostana Statistics GmbH, Charite Universitaetsmedizin Berlin, Berlin (Germany)

    2014-03-15

    In this study, the acute toxicity and long-term outcome of a hyperfractionated accelerated chemoradiation regimen with cisplatin/5-fluorouracil (5-FU) in patients with locally advanced squamous cell carcinomas of head and neck were evaluated. From 2000-2002, 38 patients with stage III (5.3 %) and stage IV (94.7 %) head and neck cancer were enrolled in a phase II study. Patients received hyperfractionated-accelerated radiotherapy with 72 Gy in 15 fractions of 2 Gy followed by 1.4 Gy twice daily with concurrent, continuous infusion 5-FU of 600 mg/m{sup 2} on days 1-5 and 6 cycles of weekly cisplatin (30 mg/m{sup 2}). Acute toxicities (CTCAEv2.0), locoregional control (LRC), metastases-free (MFS), and overall survival (OS) were analyzed and exploratively compared with the ARO 95-06 trial. Median follow-up was 11.4 years (95 % CI 8.6-14.2) and mean dose 71.6 Gy. Of the patients, 82 % had 6 (n = 15) or 5 (n = 16) cycles of cisplatin, 5 and 2 patients received 4 and 3 cycles, respectively. Grade 3 anemia, leukopenia, and thrombocytopenia were observed in 15.8, 15.8, and 2.6 %, respectively. Grade 3 mucositis in 50 %, grade 3 and 4 dysphagia in 55 and 13 %. The 2-, 5-, and 10-year LRC was 65, 53.6, and 48.2 %, the MFS was 77.5, 66.7, and 57.2 % and the OS 59.6, 29.2, and 15 %, respectively. Chemoradiation with 5-FU and cisplatin seems feasible and superior in terms of LRC and OS to the ARO 95-06C-HART arm at 2 years. However, this did not persist at the 5- and 10-year follow-ups. (orig.) [German] Untersuchung der Akuttoxizitaet und des Langzeitueberlebens einer hyperfraktioniert-akzelerierten simultanen Radiochemotherapie mit Cisplatin/5-Fluorouracil (5-FU) bei Patienten mit lokal fortgeschrittenen Kopf-Hals-Tumoren. Von 2000 bis 2002 wurden 38 Patienten mit Plattenepithelkarzinomen der Kopf-Hals-Region im Stadium III (5,3 %) und IV (94,7 %) eingeschlossen. Es erfolgte eine simultane hyperfraktionierte akzelerierte Radiochemotherapie mit 72 Gy in 15 Fraktionen a 2 Gy

  10. An exploratory examination of student to professor disclosures of crime victimization.

    Science.gov (United States)

    Richards, Tara N; Branch, Kathryn A; Hayes, Rebecca M

    2013-11-01

    Prior qualitative research has demonstrated that female college students may utilize their professors as support providers when they experience sexual assault and intimate partner violence victimization. To further explore this phenomenon, the present study used a random sampling design on two college campuses to examine the following questions: (a) Are student disclosures of crime victimization a common occurrence for college professors? (b) What is the nature of college professors' most recent disclosure of crime victimization? and (c) Do professor characteristics predict receiving a student disclosure of victimization? Implications of these findings as well as directions for future research will be discussed.

  11. INCLUSÃO E PROFESSORES: REPRESENTAÇÕES DISCURSIVAS

    Directory of Open Access Journals (Sweden)

    Hanna Caroline Neyris Corrêa da Costa

    2012-12-01

    Full Text Available O tema Inclusão tem-se destacado como uma forma revolucionária da educação, entende-se que analisar os discursos veiculados sobre este tema, contribui para elucidar certos aspectos que não são ditos (as entrelinhas explicitamente, mas que direcionam a maneira de pensar e de agir da pessoa que os lê, já que quem escreveu tal artigo para a Revista tem sua história, sua ideologia, sua opinião formada sobre a temática e que influencia a maneira de pensar de quem lê tal reportagem. Partindo dos pressupostos teóricos da Análise do Discurso (AD e da educação inclusiva, pretende-se, a partir da análise do artigo “A escola que é de todas as crianças” do site da Revista Nova Escola, edição n.º 182, do mês de maio de 2005, de autoria de Meire Cavalcante, cuja temática é a educação inclusiva, entender os discursos veiculados sobre a temática, que ideias difundem, que representações o artigo da Revista sob análise veicula sobre inclusão. Portanto, na análise, conforme apregoado na manchete em questão, o termo inclusão, mediante a ação do professor, é capaz de transformar os modos de pensar e agir das pessoas com deficiência, esquecendo que, na realidade, as escolas estão deficientes em vários sentidos: estrutura física, pedagógicas e tecnológicas, falta investimento na formação de todos os envolvidos no processo ensino/aprendizagem, sendo que tudo isso interfere nos resultados do processo de inclusão, ou seja, para uma educação de maior qualidade. Não é somente a ação isolada do professor que trará resultados profícuos nesse processo. Palavras-chave: Análise do discurso. Inclusão. Professores.

  12. [Isolation and characterization of petroleum catabolic broad-host-range plasmids from Shen-Fu wastewater irrigation zone].

    Science.gov (United States)

    Wang, Ya-Fei; Wang, Ya-Fei; Li, Hui; Li, Xiao-Bin

    2013-11-01

    Based on triparental mating, we isolated a total of eight broad host range (BHR) petroleum hydrocarbon catabolic plasmids from the soils, sediments, and wastewater samples in the Shen-Fu irrigation zone. The antibiotic resistance of the plasmids was tested, and then, the plasmids were transferred to Escherichia coli EC100. The plasmids carrying no antibiotic resistance were tagged by miniTn5 transposon consisting of antibiotic resistant genes. The PCR-based incompatibility test revealed that the pS3-2C and pS4-6G belonged to Inc P group, the pS3-2G, pW22-3G, and pA15-7G belonged to Inc N group, the pS7-2G was identified as Inc W plasmid, and the pA23-1G and pA10-1C were placed into Inc Q group. By adopting the reported PCR amplification methods of petroleum hydrocarbon-degrading catabolic genes, the petroleum-degrading capability of these BHR plasmids were preliminarily analyzed. The plasmids pS3-2G, pS7-2G, pA23-1G, pW22-3G, and pA10-1C carried aromatic ring- hydroxylating dioxygenase gene phdA and toluene monooxygenase gene touA; the plasmid pA15-7G carried touA and toluene dioxygenase gene tod; the plasmid pS3-2C carried ben, phdA, and tod; whereas the pS4-6G only carried ben. The host range test showed that all the isolated plasmids except pS3-2C could be transferred and maintained stably in the representative strains Agrobacterium tumefaciens C58, Cupriavidus necator JMP228, and E. coli EC100 of the alpha-, beta-, and gamma-Proteobacteria, respectively.

  13. PET-CT guided SIB-IMRT combined with concurrent 5-FU/MMC for the treatment of anal cancer.

    Science.gov (United States)

    Zimmermann, Michel; Beer, Jürgen; Bodis, Stefan; von Moos, Roger; Vlachopoulou, Vasiliki; Zwahlen, Daniel R; Oehler, Christoph

    2017-12-01

    To evaluate local control (LC), survival and toxicity in anal cancer patients treated with intensity-modulated radiation therapy (IMRT) and concurrent chemotherapy at a single institution. From August 2010 to May 2015, 26 patients were treated at our institution with IMRT and concurrent 5-fluorouracil/mitomycin-C (5-FU/MMC) for localized squamous cell carcinoma of the anal canal (SCCAC). Radiotherapy (RT) with 50.4-60 Gy was delivered with a sequential boost in 31%, and a simultaneous-integrated boost (SIB-IMRT) in 69% of cases. Initial staging was based on PET-CT and MRI. Clinical measures of interest were the influence of PET-CT on staging and treatment planning, LC, disease free survival (DFS), overall survival (OS), colostomy free survival (CFS) and toxicities. Median age was 61 years, 22 patients (85%) were female, and no patient was HIV-positive. The proportion of patients with stage I, II, IIIA and IIIB disease was 15%, 35%, 23% and 27%, respectively. PET-CT modified the extent of nodal disease in 9/23 cases (39%) and lead to major changes in treatment planning in 4/23 patients (17%). MRI was more accurate at identifying T4 disease. RT was delivered at full dose in 26 patients (100%) and chemotherapy in 22/26 patients (85%). Two patients (7.7%) required RT breaks. Median follow-up was 35 months [IQR: 19-52]. The 2-year LC, DFS, OS and CFS were 100%, 100%, 100% and 92%. Acute grade ≥3 dermatitis and diarrhea occurred in 73% and 8% of cases, respectively. Grade 3-4 neutropenia was seen in 10/23 patients (43%). Four patients (15%) developed chronic grade 2 GI toxicity. PET-CT provided additional information leading to major changes in treatment planning for 17% of patients. Considering our excellent outcomes, routine use of PET-CT as standard staging modality and IMRT planning procedure appears justified for patients with SCCAC.

  14. Effect of Shen-Fu Injection Pretreatment to Myocardial Metabolism During Untreated Ventricular Fibrillation in a Porcine Model.

    Science.gov (United States)

    Yuan, Wei; Wu, Jun-Yuan; Wang, Guo-Xing; Zhang, Qian; Li, Chun-Sheng

    2015-11-20

    Shen-Fu injection (SFI) can attenuate ischemia-reperfusion injury, protect cardiac function, and improve microcirculation during cardiopulmonary resuscitation. We hypothesized that SFI may also have an influence on myocardial metabolism during ventricular fibrillation (VF). In this study, we used SFI pretreatment prior to VF to discuss the changes of myocardial metabolism and catecholamine (CA) levels during untreated VF, trying to provide new evidence to the protection of SFI to myocardium. Twenty-four pigs were divided into three groups: Saline group (SA group), SFI group, and SHAM operation group (SHAM group). Thirty minutes prior to the induction of VF, the SFI group received 0.24 mg/ml SFI through an intravenous injection; the SA group received an equal amount of sodium chloride solution. The interstitial fluid from the left ventricle (LV) wall was collected through the microdialysis tubes during VF. Adenosine diphosphate (ADP), adenosine triphosphate (ATP), and Na + -K + -ATPase and Ca2 + -ATPase enzyme activities were measured after untreated VF. Peak-to-trough VF amplitude and median frequency were analyzed for each of these 5-s intervals. The levels of glucose and glutamate were lower after VF in both the SA and SFI groups, compared with baseline, and the levels in the SFI group were higher than those in the SA group. Compared with baseline, the levels of lactate and the lactate/pyruvate ratio increased after VF in both SA and SFI groups, and the levels in the SFI group were lower than those in the SA group. In both the SA and SFI groups, the levels of dopamine, norepinephrine, and epinephrine increased significantly. There were no statistical differences between the two groups. The content of ATP, ADP, and phosphocreatine in the SFI group was higher than those in the SA group. The activity of LV Na + -K + -ATPase was significantly higher in the SFI group than in the SA group. Amplitude mean spectrum area (AMSA) was significantly lower in the SA and SFI

  15. Effect of Shen-Fu Injection Pretreatment to Myocardial Metabolism During Untreated Ventricular Fibrillation in a Porcine Model

    Directory of Open Access Journals (Sweden)

    Wei Yuan

    2015-01-01

    Full Text Available Background: Shen-Fu injection (SFI can attenuate ischemia-reperfusion injury, protect cardiac function, and improve microcirculation during cardiopulmonary resuscitation. We hypothesized that SFI may also have an influence on myocardial metabolism during ventricular fibrillation (VF. In this study, we used SFI pretreatment prior to VF to discuss the changes of myocardial metabolism and catecholamine (CA levels during untreated VF, trying to provide new evidence to the protection of SFI to myocardium. Methods: Twenty-four pigs were divided into three groups: Saline group (SA group, SFI group, and SHAM operation group (SHAM group. Thirty minutes prior to the induction of VF, the SFI group received 0.24 mg/ml SFI through an intravenous injection; the SA group received an equal amount of sodium chloride solution. The interstitial fluid from the left ventricle (LV wall was collected through the microdialysis tubes during VF. Adenosine diphosphate (ADP, adenosine triphosphate (ATP, and Na + -K + -ATPase and Ca2 + -ATPase enzyme activities were measured after untreated VF. Peak-to-trough VF amplitude and median frequency were analyzed for each of these 5-s intervals. Results: The levels of glucose and glutamate were lower after VF in both the SA and SFI groups, compared with baseline, and the levels in the SFI group were higher than those in the SA group. Compared with baseline, the levels of lactate and the lactate/pyruvate ratio increased after VF in both SA and SFI groups, and the levels in the SFI group were lower than those in the SA group. In both the SA and SFI groups, the levels of dopamine, norepinephrine, and epinephrine increased significantly. There were no statistical differences between the two groups. The content of ATP, ADP, and phosphocreatine in the SFI group was higher than those in the SA group. The activity of LV Na + -K + -ATPase was significantly higher in the SFI group than in the SA group. Amplitude mean spectrum area (AMSA was

  16. The influence of surface water - groundwater interactions on the shallow groundwater in agricultural areas near Fu River, China

    Science.gov (United States)

    Brauns, Bentje; Løgstrup Bjerg, Poul; Jakobsen, Rasmus; Song, Xianfang

    2014-05-01

    The Northern China Plain (NPC) is known as a very productive area in China for the production of maize and winter wheat, which is grown by local farmers rotationally without lag phases throughout the year. The needed application of fertilizers and pesticides can hereby have strong impacts on the quality shallow groundwaters. Because 70-80% percent of the annual rainfall in the NCP is limited to the summer months, irrigation in the spring season is a necessity. As high quality groundwater resources from deeper aquifers are a valuable and rare asset in Northern China, it should preferentially be used as drinking water, and farmers therefore often shift to flood irrigation with surface water from streams. It is due to this reason, that large agricultural areas are located very close alongside these waterways; often without buffer zones. Fu River is one of the major feeding streams for the Baiyangdian Lake region in the north of Hebei Province. It springs in the west of the lake area and - after passing the populated city of Baoding (with a population of about 600 000 in the metropolitan area) - continues on its course through agricultural area before it feeds into the lake system. Industrial and domestic wastewater as well as surface runoff from urban and agricultural areas substantiates for a significant amount of the river's recharge and often causes poor water quality. As the water from the river may infiltrate into the shallow groundwater, this could cause further deterioration of the groundwater quality, additionally to the effects of the agricultural activities. However, fluctuations may be high because of the strong seasonal differences in precipitation and depending on the connectivity and dynamics of the system . In order to assess the water quality situation and the potential link between surface water and shallow groundwater in the region, a small-scale investigation site was set up on a typical wheat-maize field that reaches almost up to the river bank in

  17. Students’ Needs Analysis in an EFL Program for University Professors

    Directory of Open Access Journals (Sweden)

    Paula Andrea Bedoya

    2015-10-01

    Full Text Available This study sets out to investigate professors’ needs from an English as a foreign language program in a public university regarding demands, interests, and lacks based on the methodology of needs analysis. Data collected through a survey, focus groups, and individual interviews showed that professors need to meet the institutional language policy for contractual and academic reasons. Additionally, data revealed their desire to learn English to communicate in both academic and non-academic settings. Moreover, the lack of time and effective learning strategies were reported as comprising the main constraints for learning. Finally, the authors present the strengths and weaknesses of the program as well as the participants’ suggestions for curriculum restructuring.

  18. Professor Lesley Parker: a science educator writ large

    Science.gov (United States)

    Kahle, Jane Butler

    2011-09-01

    Professor Lesley Parker's career has moved from teaching and advising graduate students at Curtin University of Technology, Perth, Western Australia to leadership roles and advocacy positions in state and national governments and in international organizations. Throughout her distinguished career, she has been committed to social justice, particularly in gender equity. Indeed, that commitment infuses her professional contributions as teacher, advisor, administrator, and policy maker. In this Key Contribution, many of her colleagues describe their admiration for her as well as provide information that helps the reader place her work in a national and an international perspective. She has received many of Australia's highest honors, and she continues to contribute to her university, her state, and her nation. Her contributions form a lasting legacy in social justice, particularly in gender equity and in educational leadership.

  19. Tribute to Professor Anthony J. McMichael

    Directory of Open Access Journals (Sweden)

    Ashwin Swaminathan

    2014-11-01

    Full Text Available Emeritus Professor A. J. “Tony” McMichael (1942–2014 was an internationally renowned and pioneering Australian academic and advocate in epidemiology, who was passionate about understanding the influences of the environment on human health. In an illustrious career spanning more than four decades, he made significant contributions to the scientific community and policy discourse—including ground-breaking research related to the health of children. McMichael was a prolific academic writer with over 300 peer-reviewed papers; 160 book chapters and two sole-authored books. However, his outstanding talent was for integrating complex and seemingly unrelated strands from the environmental and health sciences into a cohesive narrative—and highlighting its relevance to lay persons, scientists and governments alike. He was instrumental in validating this nascent field of research and inspiring many others to follow his lead.

  20. Quality of life research: interview with Professor Robert Cummins

    Directory of Open Access Journals (Sweden)

    Robert Cummins

    2013-09-01

    Full Text Available Health-related quality of life (HRQOL is a fundamental concept in the field of clinical medicine and has been studied during the last years by psychologists, sociologists, economists and managers. The concept of HRQOL includes those aspects of overall QOL that can be indicated to have an impact on patients’ health, either physical or psychological. Concerning the individuals, this incorporates physical and mental health cognitions, including sociodemographic factors, sexual functioning, fatigue, sleep disorders and functional status. One of the most eminent experts in the world in the field of QOL is Prof. Robert Cummins [Professor of Psychology at Deakin University in Australia (School of Psychology, Deakin University, 221 Burwood Highway, Victoria 3125 Melbourne, Australia. E-mail: robert.cummins@deakin.edu.au] who kindly accepted to answer our questions in the con- text of this special edition.

  1. Memorial meeting for professor Abdus Salam's 90th birthday

    CERN Document Server

    Duff, Michael; Khoo Phua, Kok; Memorial volume on Abdus Salam's 90th birthday

    2017-01-01

    In honor of one of the most prolific and exciting scientists of the second half of the last century, a memorial meeting was organized by the Institute of Advanced Studies at Nanyang Technological University for Professor Abdus Salam's 90th Birthday in January 2016. Salam believed that "scientific thought is the common heritage of all mankind" and that the developing world should play its part, not merely by importing technology but by being the arbiter of its own scientific destiny. That belief saw him rise from humble beginnings in a village in Pakistan to become one of the world's most original and influential particle physicists, culminating in the 1979 Nobel Prize (shared with Glashow and Weinberg) for contributions to electroweak unification, which forms an integral part of the Standard Model. The book collected the papers presented at this memorable event which saw many distinguished scientists participating as speakers to reflect on Prof Salam's great passion for the science and achievements.

  2. Julio López Rendueles, a revolutionary professor

    Directory of Open Access Journals (Sweden)

    Zoila Rodríguez-Gobea

    2017-05-01

    Full Text Available Julio López Rendueles was part of the group of Spanish exiles who joined the rising University of Oriente, and contributed decisively to the development of this center of high studies and to the revolutionary struggle that was taking place in the nation led by Movement 26 of July. This work shows that, before arriving in Cuba, Professor López Rendueles was a prestigious intellectual and a prominent communist militant, defender of the Spanish Republic. After the triumph of the Revolution he moved to Havana, where he continued to collaborate with the Revolutionary Armed Forces in the creation of Camilo Cienfuegos Military Schools and with the Ministry of Education in the organization of polytechnic teaching and in writing books for the teaching of chemistry, physics and mathematics.

  3. H.E. Professor Wang Liheng, Minister of Aviation of the People's Republic of China, President, China Aerospace Science & Technology Corporation

    CERN Multimedia

    Patrice Loïez

    2001-01-01

    H. E. Professor Wang Liheng, Minister of Aviation, and President, China Aerospace Science & Technology Corporation, People's Republic of China (2nd from left) with (from left to right) Professor Hans Hofer, Professor Roger Cashmore, Research Director for Collider Programmes, Professor Samuel C. C. Ting, CERN and Professor Lei Gang, Secretary to the Minister, September 2001.

  4. As interações professor-professor na co-construção dos projetos pedagógicos na escola

    Directory of Open Access Journals (Sweden)

    Mírian Raposo

    Full Text Available A qualidade das interações entre professores é uma realidade da cultura escolar de fundamental importância para o desenvolvimento do seu projeto pedagógico e do currículo vivido pelo aluno. Arquitetado nos pressupostos teóricos da abordagem sociocultural construtivista, este trabalho teve como objetivo investigar os processos co-construtivos presentes nas interações professor-professor, fundamentais para a elaboração e execução dos projetos vividos em uma escola pública de formação de professores do Distrito Federal. Participaram do estudo os 23 professores do curso normal, a coordenadora e o diretor. Procedimentos de observação participante das atividades pedagógicas de planejamento e execução de projetos e entrevista semi-estruturada com 10 desses participantes foram realizados em um período de três meses. A análise dos resultados focalizou (1 relações de confiança (2 interdependência indivíduo-grupo e (3 liderança. Estas categorias foram cruciais para o alcance dos objetivos estabelecidos na escola. Considera-se que estas são contribuições importantes da Psicologia aos cursos de formação inicial e continuada de professores.

  5. Promotion beyond Tenure: Unpacking Racism and Sexism in the Experiences of Black Womyn Professors

    Science.gov (United States)

    Croom, Natasha N.

    2017-01-01

    This study examined seven Black womyn full professors' experiences of promotion beyond tenure. Using a critical race feminist theoretical framework, findings suggest that a meritocratic ideology undergirds a dominant narrative about the Professor rank. However, racism and sexism mediated the participants' opportunities to access the status and…

  6. Messaggio del professor Antonino Zichichi in occasione dell’International Cosmic Day (30 novembre) 2017.

    CERN Multimedia

    2017-01-01

    Messaggio del professor Antonino Zichichi in occasione dell’International Cosmic Day (30 novembre) 2017. Nella prima parte il professore spiega l’importanza per la scienza dei raggi cosmici, ieri come oggi. nella seconda parte si rivolge ai ragazzi che partecipano all’ICD 2017 per il progetto EEE del Centro Fermi

  7. "Simply the Best": Professors Nominated by Students for Their Exemplary Technology Practices in Teaching

    Science.gov (United States)

    Jorgensen, Mary; Havel, Alice; Fichten, Catherine; King, Laura; Marcil, Evelyne; Lussier, Alex; Budd, Jillian; Vitouchanskaia, Cristina

    2018-01-01

    Our goal was to explore the technology related pedagogical practices of college professors deemed by their students to be excellent in using technology in their teaching. We explored the views of 114 community/junior college professors who were nominated by their students as excellent in using technology in their teaching using both questionnaires…

  8. Student teachers can be as good as associate professors in teaching clinical skills

    DEFF Research Database (Denmark)

    Tolsgaard, Martin G; Gustafsson, Amandus; Rasmussen, Maria B

    2007-01-01

    AIM: The aim of this study is to compare student teachers and clinical associate professors regarding the quality of procedural skills teaching in terms of participants' technical skills, knowledge and satisfaction with the teaching. METHODS: This is an experimental, randomized, controlled study ....... CONCLUSION: Trained student teachers can be as good as associate professors in teaching clinical skills. Udgivelsesdato: 2007-Sep...

  9. Chip Frazier named Thomas M. Brooks Professor of Wood Science and Forest Products

    OpenAIRE

    Davis, Lynn

    2007-01-01

    Charles E. "Chip" Frazier of Blacksburg, professor of wood science and forest products in the College of Natural Resources at Virginia Tech, has been appointed the Thomas M. Brooks Professor of Wood Science and Forest Products by the Virginia Tech Board of Visitors during the board's quarterly meeting March 26.

  10. Professor as Facilitator: Shaping an Emerging, Living System of Shared Leadership in the Classroom

    Science.gov (United States)

    Bright, David S.; Turesky, Elizabeth Fisher; Putzel, Roger; Stang, Thomas

    2012-01-01

    From the perspective of emergence, professors can facilitate and shape a class as a complex, adaptive, and living system. A case study illustrates phases of emergence in the classroom by tracing how a professor may use this perspective to empower students to share in the leadership of the classroom. Instead of presenting lessons, the professor…

  11. Romans 12 Motivational Gifts and College Professors: Implications for Job Satisfaction and Person-Job Fit

    Science.gov (United States)

    Tomlinson, Jon C.; Winston, Bruce E.

    2011-01-01

    This study builds on earlier work by DellaVecchio and Winston (2004) and McPherson (2008). They addressed the seven motivational gifts Paul wrote about in Romans 12:3-8 as a means for addressing job satisfaction and person-job fit among college professors. Using a snowball sampling method, 89 college professors completed the online survey…

  12. College Professors' Perceptions of and Responses to Relational Aggression in College Students

    Science.gov (United States)

    Fifield, Andrea Owens

    2010-01-01

    The purpose of this study was to investigate the impact of selected factors on professors' responses to relational aggression in college students. Specifically, this study explored the relationships between professors' gender, class size, level of empathy, ratings of seriousness of a relationally aggressive scenario, the gender of the perpetrator…

  13. Crossing the Bridge: Transitioning from a K-12 Teacher to a College Professor

    Science.gov (United States)

    Page, Steven; Jenks, Charles

    2012-01-01

    This is a qualitative study that was conducted to gain a better understanding of the experiences of professors in Colleges of Education who were former K-12 teachers. The study presents the responses of eighty-nine professors from across the United States. Coding based on the university setting (national, large regional, small regional) in which…

  14. A Narrative Inquiry Exploring How College Communication Professors Engage Students with Public Speaking Apprehension

    Science.gov (United States)

    Riedel, Derek

    2012-01-01

    The purpose of this qualitative study was to discover how communication professors at four-year private universities help students who exhibit public speaking apprehension (PSA) learn to cope with their anxiety. The research was framed in the narrative inquiry paradigm, interviewing eight college communication professors about their experiences…

  15. Exploring Cultural Effects on Teaching Styles of Chinese and American Professors

    Science.gov (United States)

    Zhan, Ginny Q.; Moodie, Douglas R.; Wang, Bailing

    2015-01-01

    The current study examines cultural effects on college professors' teaching styles. Ninety-four Chinese university instructors participated in the study. A 40-item teaching style inventory was used in the study. The responses were compared with American professors' teaching styles reported by Grasha (2006). Results show that the Chinese…

  16. Strategies for Professors Who Service the University to Earn Tenure and Promotion

    Science.gov (United States)

    Gentry, Ruben; Stokes, Dorothy

    2015-01-01

    Tenure and promotion are great aspirations for college professors. They are indicators of success in the professions. Universities stipulate in their official documents and numerous higher education publications specify what professors must achieve in order to earn tenure and promotion; which almost always cite effectiveness in teaching, research,…

  17. "Putting in Your Time": Faculty Experiences in the Process of Promotion to Professor

    Science.gov (United States)

    Gardner, Susan K.; Blackstone, Amy

    2013-01-01

    The rank of professor or "full" professor represents the highest status possible for faculty members, and it is generally gained by attaining professional expertise and a national or international reputation. Beyond this, however, little is known about these individuals or the promotion process at this level. In this qualitative study of…

  18. H.E. Professor Dragoljub Popovic, Ambassador to Switzerland of the Federal Republic of Yugoslavia

    CERN Multimedia

    Patrice Loïez

    2001-01-01

    H. E. Professor Dragoljub Popovic, Ambassador of the Federal Republic of Yugoslavia to Switzerland, visiting the ATLAS cavern. From left to right: Dr Torsten Akesson, Deputy Spokesman of the ATLAS experiment; H. E. Professor Dragoljub Popovic; Mrs Simone Hajos, Project Engineer, LHC civil engineering; Dr Peter Adzic, Chairman of the Committee of the Republic of Serbia for relations with CERN.

  19. Professor: Polens reformer er værre for EU end brexit

    DEFF Research Database (Denmark)

    Wind, Marlene

    2017-01-01

    Professor Marlene Wind var den 8. december i Jyllands-Posten, hvor hun kommenterede på udviklingen i Polen med deres retsreformer, som professor Wind vurderer er mere alvorlig end Brexit for EU. Sagen om Polen handler om, hvordan EU kan få dets medlemslande til at overholde de regler og værdier...

  20. A Comparison of Mathematics Teachers' and Professors' Views on Secondary Preparation for Tertiary Calculus

    Science.gov (United States)

    Wade, Carol; Sonnert, Gerhard; Sadler, Philip M.; Hazari, Zahra; Watson, Charity

    2016-01-01

    This article compares the views of teachers and professors about the transition from secondary mathematics to tertiary calculus. Quantitative analysis revealed five categories where teachers and professors differed significantly in the relative frequency of addressing them. Using the rite of passage theory, the separation and incorporation phases…

  1. Acculturative Stress, Parental and Professor Attachment, and College Adjustment in Asian International Students

    Science.gov (United States)

    Han, Suejung; Pistole, M. Carole; Caldwell, Jarred M.

    2017-01-01

    This study examined parental and professor attachment as buffers against acculturative stress and as predictors of college adjustment of 210 Asian international students (AISs). Moderated hierarchical regression analyses revealed that acculturative stress negatively and secure parental and professor attachment positively predicted academic…

  2. Robert Beichner joins university as American Council of Education Fellow and visiting professor of physics

    OpenAIRE

    Owczarski, Mark

    2010-01-01

    Robert Beichner, Alumni Distinguished Professor of Physics and director of the Science, Technology, Engineering and Mathematics Education Initiative at North Carolina State University, will spend the fall semester as the American Council of Education Fellow and visiting professor of physics in the College of Science.

  3. A New Approach to Faculty-Librarian Collaboration: A ''New Professors' Fund'' for Collection Development

    Science.gov (United States)

    Horava, Tony

    2005-01-01

    The University of Ottawa implemented a "New Professors" Fund as a targeted strategy for establishing a collaborative relationship between new faculty and librarians. An amount of $2000 per professor was earmarked for selection. The rationale, process, and outcomes of the initiative are described. The impact on collection development is…

  4. (Re)Defining Departure: Exploring Black Professors' Experiences with and Responses to Racism and Racial Climate

    Science.gov (United States)

    Griffin, Kimberly A.; Pifer, Meghan J.; Humphrey, Jordan R.; Hazelwood, Ashley M.

    2011-01-01

    A growing body of research demonstrates that many college environments present challenges for black professors, particularly as they face institutional and personal racism. While scholars have linked these experiences to their attrition, this qualitative study explores black professors' larger range of responses to difficult professional…

  5. Establishment of a new human pleomorphic malignant fibrous histiocytoma cell line, FU-MFH-2: molecular cytogenetic characterization by multicolor fluorescence in situ hybridization and comparative genomic hybridization

    Directory of Open Access Journals (Sweden)

    Isayama Teruto

    2010-11-01

    Full Text Available Abstract Background Pleomorphic malignant fibrous histiocytoma (MFH is one of the most frequent malignant soft tissue tumors in adults. Despite the considerable amount of research on MFH cell lines, their characterization at a molecular cytogenetic level has not been extensively analyzed. Methods and results We established a new permanent human cell line, FU-MFH-2, from a metastatic pleomorphic MFH of a 72-year-old Japanese man, and applied multicolor fluorescence in situ hybridization (M-FISH, Urovysion™ FISH, and comparative genomic hybridization (CGH for the characterization of chromosomal aberrations. FU-MFH-2 cells were spindle or polygonal in shape with oval nuclei, and were successfully maintained in vitro for over 80 passages. The histological features of heterotransplanted tumors in severe combined immunodeficiency mice were essentially the same as those of the original tumor. Cytogenetic and M-FISH analyses displayed a hypotriploid karyotype with numerous structural aberrations. Urovysion™ FISH revealed a homozygous deletion of the p16INK4A locus on chromosome band 9p21. CGH analysis showed a high-level amplification of 9q31-q34, gains of 1p12-p34.3, 2p21, 2q11.2-q21, 3p, 4p, 6q22-qter, 8p11.2, 8q11.2-q21.1, 9q21-qter, 11q13, 12q24, 15q21-qter, 16p13, 17, 20, and X, and losses of 1q43-qter, 4q32-qter, 5q14-q23, 7q32-qter, 8p21-pter, 8q23, 9p21-pter, 10p11.2-p13, and 10q11.2-q22. Conclusion The FU-MFH-2 cell line will be a particularly useful model for studying molecular pathogenesis of human pleomorphic MFH.

  6. Suppression of microRNA-31 increases sensitivity to 5-FU at an early stage, and affects cell migration and invasion in HCT-116 colon cancer cells

    Directory of Open Access Journals (Sweden)

    Sun Xiao-Feng

    2010-11-01

    Full Text Available Abstract Background MicroRNAs (miRNAs are endogenously expressed noncoding RNAs with important biological and pathological functions. Although several studies have shown that microRNA-31 (miR-31 is obviously up-regulated in colorectal cancer (CRC, there is no study on the functional roles of miR-31 in CRC. Methods Anti-miR™ miRNA 31 inhibitor (anti-miR-31 is a sequence-specific and chemically modified oligonucleotide to specifically target and knockdown miR-31 molecule. The effect of anti-miR-31 transfection was investigated by real-time PCR. HCT-116p53+/+ and HCT-116p53-/-colon cancer cells were treated by anti-miR-31 with or without 5-fluorouracil (5-FU, cell proliferation was determined by MTT assay; apoptosis was detected by DAPI staining; cell cycle was evaluated by flow cytometry; colony formation, migration and invasion assays were performed to investigate the effect of suppression of miR-31 on the cell lines. Results Real-time PCR results showed that anti-miR-31 was efficiently introduced into the cells and reduced miR-31 levels to 44.1% in HCT-116p53+/+ and 67.8% in HCT-116p53-/-cell line (p = 0.042 and 0.046. MTT results showed that anti-miR-31 alone had no effect on the proliferation of HCT-116p53+/+ or HCT-116p53-/-. However, when combined with 5-FU, anti-miR-31 inhibited the proliferation of the two cell lines as early as 24 h after exposure to 5-FU (p = 0.038 and 0.044. Suppression of miR-31 caused a reduction of the migratory cells by nearly 50% compared with the negative control in both HCT-116p53+/+ and HCT-116p53-/-(p = 0.040 and 0.001. The invasive ability of the cells were increased by 8-fold in HCT-116p53+/+ and 2-fold in HCT-116p53-/- (p = 0.045 and 0.009. Suppression of miR-31 had no effect on cell cycle and colony formation (p > 0.05. Conclusions Suppression of miR-31 increases sensitivity to 5-FU at an early stage, and affects cell migration and invasion in HCT-116 colon cancer cells.

  7. Des oiseaux et des femmes. Quelques remarques sur la grue du fabliau de "Celle qui fu foutue et desfoutue" 

    OpenAIRE

    Pierreville, Corinne

    2006-01-01

    International audience; "Celle qui fu foutue et desfoutue par une grue" est un court fabliau de 160 octosyllabes composé dans le premier tiers du XIIIe siècle par un auteur que le prologue nomme Garin. Une demoiselle d’une grande beauté, fille d’un châtelain, est enfermée par son père dans une tour sous la garde d’une nourrice. Un jour, sa duègne la laisse seule, un instant, pour aller chercher une assiette. Passe un jeune homme tenant une grue dans la main droite. La demoiselle s’extasie dev...

  8. Discurso da autoajuda na formação do professor de língua

    Directory of Open Access Journals (Sweden)

    Wagner Rodrigues SILVA

    2013-10-01

    Full Text Available Este trabalho investiga a interferência do discurso de autoajuda nas representações de professor, construídas por alunos-mestres no contexto de formação de professores de língua. O embasamento teórico ancora-se no conceito de transdisciplinaridade como um fator central para a prática científica pós-moderna em Linguística Aplicada. Os resultados mostram que os discursos da autoajuda responsabilizam os professores tanto pelo sucesso quanto pelo fracasso de seus aprendizes. Consequentemente, o uso desse tipo de linguagem, durante os cursos de treinamento de professores, pode camuflar o empoderamento do professor, o que, por sua vez, pode comprometer a sua formação

  9. [Japanese pharmaceutical professors of a medical university and colleges in colonial Korea (1916-1945)].

    Science.gov (United States)

    Ishida, Sumio

    2011-01-01

    This study investigates the 14 Japanese pharmaceutical professors who worked in colonial Korea from 1916 to 1945. Of these professors, four worked at Keijyo Imperial University, five worked at Keijyo Medical College, two worked at Taikyu Medical College and two worked at Heijyo Medical College. Nine were physicians and four were pharmacists. Four persons graduated from Tokyo Imperial University, one from Kyoto Imperial University, two from Kumamoto Medical College, one from Toyama Pharmaceutical College, one from Nagasaki Medical College, one from Okayama Medical College and one unknown. A medical degree was obtained by 9 of 14 professors (69.2%), a high rate compared to the same grade of medical institution in Japan at that time. Regarding the positions of the professors in Japan after the end of the Second World War in 1945, four obtained professor positions at universities, three were clinical doctors, one worked for a pharmaceutical company, one was a researcher at an institute, one died and three are unknown.

  10. 2784-IJBCS-Article-Kevin Sagui Kassa

    African Journals Online (AJOL)

    hp

    Ces facteurs sont d'ordres génétique et non génétique et méritent d'être élucidés dans le cadre de l'amélioration de la production du lait des vaches. Cet article passe en revue les effets des principaux facteurs non génétiques (stade de lactation, rang de mise bas, saison de mise bas, alimentation, etc.) et génétiques (race ...

  11. visit of Members of the ETH Foundation, accompanied by Professor Heidi Wunderli-Allenspach, Rektorin, ETH Zürich and Professor Roman Boutellier, Vizepräsident Personal und Ressourcen, Switzerland, on Tuesday, 24th February 2009.

    CERN Multimedia

    Maximilien Brice

    2009-01-01

    visit of Members of the ETH Foundation, accompanied by Professor Heidi Wunderli-Allenspach, Rektorin, ETH Zürich and Professor Roman Boutellier, Vizepräsident Personal und Ressourcen, Switzerland, on Tuesday, 24th February 2009.

  12. Summer students and professor from the United Arab Emirates - from left to right : Alya Ali Binghurair, Shaikha Al Kalbani, Professor Chafia Hejase de Trad, Mariam Al Hassani, Aminah Al Abdouli.

    CERN Multimedia

    Maximilien Brice

    2004-01-01

    Summer students and professor from the United Arab Emirates - from left to right : Alya Ali Binghurair, Shaikha Al Kalbani, Professor Chafia Hejase de Trad, Mariam Al Hassani, Aminah Al Abdouli.

  13. CERN 50th Anniversary Official Celebration : keynote speech from Professor Federico Mayor Zaragoza, Professor in the Molecular Biology at the Universidad Autónoma of Madrid, Former Director-General of UNESCO

    CERN Document Server

    Michel Blanc

    2004-01-01

    CERN 50th Anniversary Official Celebration : keynote speech from Professor Federico Mayor Zaragoza, Professor in the Molecular Biology at the Universidad Autónoma of Madrid, Former Director-General of UNESCO

  14. REDES SOCIAIS E FORMAÇÃO DE PROFESSORES

    Directory of Open Access Journals (Sweden)

    Gilmara Teixeira Barcelos

    2012-09-01

    Full Text Available Os desafios estabelecidos pelas inovações tecnológicas ao processo educativo são muitos e diversas são as alternativas de práticas pedagógicas que envolvem o uso das mesmas. Nessa perspectiva, esta conferência visa a apresentar uma pesquisa que discute a prática pedagógica alicerçada nas tecnologias digitais (TD como instrumentos mediadores. Considerando que a formação de professores é um processo contínuo, foi elaborada uma proposta de formação, para os egressos da licenciatura em Matemática de um Instituto Federal, no início de sua prática docente . A proposta foi denominada T-PROIM – Tecnologias na Prática docente de pROfessores Iniciantes de Matemática. Uma rede social na Internet (RSI foi implementada por meio da plataforma Elgg para apoiar a referida formação. Essa visou a possibilitar a integração das TD à prática docente e fundamentou-se na teoria sócio-histórica. A pesquisa foi descritiva e explicativa, por meio de um estudo de caso e a abordagem foi, predominantemente, qualitativa. As técnicas de coleta de dados foram questionário, entrevistas, observação e registro dos conteúdos postados na RSI. Para tanto, inicialmente, caracterizam-se redes sociais na internet. A seguir, são apresentados os aspectos metodológicos, as características da formação T-PROIM e a análise macro da experimentação da referida formação. Finalizando, são tecidas algumas considerações sobre a pesquisa. A flexibilidade da formação e da configuração de recursos RSI foi considerada importante para o contexto educacional. Além disso, a análise possibilitou identificar que a confiança no uso pedagógico das TD aumentou e que a formação contribuiu para o desenvolvimento pessoal, social e cognitivo.

  15. Combination of 5-FU Cisplatinum and hypofractionated irradiation followed by split-course radiotherapy in 47 patients with unresectable non small cell lung cancer

    Energy Technology Data Exchange (ETDEWEB)

    Bolla, M.; Nagy-Mignotte, H.; Moro, D.; Brambilla, C.; Paramelle, B.; Vincent, F.; Kolodie, H.; Vrousos, C. (Centre Hospitalier Universitaire, 38 - Grenoble (France))

    1992-11-01

    47 Patients with unresectable non small cell lung carcinoma, 15 stage IIIA, 31 stage IIIB, 1 stage IV (cervical lymphadenopathy) were treated with a combination of 3 courses of chemotherapy and hypofractionated irradiation followed after 3 weeks by split course radiotherapy. Each course was repeated every 3 weeks with the following sequence: Cisplatinum (CDDP) (20 mg/m[sup 2]) was given in a 20-min infusion, followed by a 2-h infusion of 5-fluorouracil (5-FU) (400 mg/m[sup 2]) on days 1, 2, 5 and 6. Radiation with a dose of 3 Gy on the target volume was given on days 3 and 4 -in one fraction for the former 27 patients, in 2 fractions of 1.5 Gy for the latter 20 patients with a 6-h interval- after a 2-h infusion of 5-FU (400 mg/m[sup 2]). The results remain disappointing: the objective response rate was 53%, the median survival was 10 months for the series, and the one-year survival 47%. The median survival was 14 months for IIIA, 10 months for IIIB and IV. Regarding the therapeutic regimen there seems to be less morbidity with 2 fractions per day for which the median survival is nearly the same at 10 months (1 fraction/day) versus 12 months (2 fractions/day). (author). 21 refs., 1 fig., 5 tabs.

  16. Effects of Shen-Fu Injection on the Expression of T-Cell-Specific Transcription Factors T-bet/Gata-3 in Porcine Postresuscitation Lung Injury

    Directory of Open Access Journals (Sweden)

    Wei Gu

    2013-01-01

    Full Text Available Shen-Fu injection (SFI derived from the ancient traditional Chinese medicine. In this study, the effects of SFI on the expression of T-bet/GATA-3 and its potential mechanisms causing the shift of T cells from Th2 to Th1 on postresuscitation lung injury were examined in a porcine model of cardiac arrest. 30 pigs were randomly divided into SHAM ( and three return of spontaneous circulation (ROSC groups ( per group; 24 pigs were subjected to 8 min of electrically induced cardiac arrest and 2 min of basic life support, which received central venous injection of Shen-Fu (SFI, epinephrine (EP or saline (SA. After successful ROSC, 18 surviving pigs were sacrificed at 24 h after ROSC ( per group. The levels of serum and lung tissue interleukin (IL-4 and interferon (IFN-γ were measured by ELISA, and the protein and mRNA levels of GATA-3 and T-bet in the lung tissue were determined by western blotting and quantitative real-time polymerase chain reaction, respectively. Compared with the EP and SA groups, SFI treatment reduced the levels of IL-4 (, increased levels of IFN-γ (, and induced T-bet mRNA upregulation and GATA-3 mRNA downregulation (. SFI attenuated lung injury and regulated lung immune disorders. Therefore, SFI could protect postresuscitation lung injury by modulating a Th1/Th2 imbalance.

  17. Decreased [{sup 18}F]fluoro-2-deoxy-D-glucose incorporation and increased glucose transport are associated with resistance to 5FU in MCF7 cells in vitro

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Tim A.D. [PET Unit, Department of Biomedical Physics, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD (United Kingdom)], E-mail: t.smith@biomed.abdn.ac.uk; Sharma, Rituka I. [PET Unit, Department of Biomedical Physics, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD (United Kingdom); Wang, Weiguang G. [Department of Medicine and Therapeutics, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD (United Kingdom); School of Applied Sciences, University of Wolverhampton, City Campus-South, Wolverhampton WV1 1SB (United Kingdom); Welch, Andy E.; Schweiger, Lutz F. [PET Unit, Department of Biomedical Physics, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD (United Kingdom); Collie-Duguid, Elaina S.R. [Department of Medicine and Therapeutics, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD (United Kingdom)

    2007-11-15

    Introduction: Tumor refractoriness to chemotherapy is frequently due to the acquisition of resistance. Resistant cells selected by exposure to chemotherapy agents may exhibit differences in [{sup 18}F]fluoro-2-deoxy-D-glucose (FDG) incorporation, as compared with sensitive cells. Methods: FDG incorporation, hexokinase (HK) activity, glucose transport and ATP content were determined in clones of 5-fluorouracil (5FU)-resistant MCF7 cells, established by long-term exposure to increasing 5FU concentrations, and in parental MCF7 cells. Results: FDG incorporation was decreased in MCF7 cells resistant to 5FU; HK activity was similar in the resistant and sensitive cells, while glucose transport was increased, as compared with sensitive cells. Treatment of cells with the glucose efflux inhibitor phloretin increased FDG incorporation to similar levels in the resistant and sensitive cells. Analysis of microarray data demonstrated the expression of GLUT1, 8 and 10 transporters in MCF7 cells. GLUT8 and 10 expression was decreased in the resistant cells, while GLUT1 was only increased in cells resistant to the lowest 5FU concentration. Conclusion: FDG incorporation in 5FU-resistant MCF7 cells is decreased, as compared with sensitive cells. Our findings also suggest that this may be due to high rates of membrane glucose transport in the resistant cells resulting in enhanced efflux of FDG. We believe that this is the first demonstration that facilitative glucose transporters can actually decrease the incorporation of FDG.

  18. O ENSINO DE LIBRAS PARA SURDOS – UMA VISÃO DE PROFESSORES SURDOS

    Directory of Open Access Journals (Sweden)

    Carolina Hessel Silveira

    2009-03-01

    Full Text Available O objetivo do presente estudo, parte de Dissertação de Mestrado em Educação, foi analisar representações que professores surdos de Língua de Sinais têm em relação aos objetivos, à importância e às dificuldades do próprio ensino de LIBRAS. O suporte teórico veio dos Estudos Culturais e dos Estudos Surdos. Foram entrevistados 10 professores surdos de escolas do Rio Grande do Sul, sendo suas entrevistas realizadas em LIBRAS e gravadas em vídeo. As perguntas das entrevistas foram: qual a função do ensino de Língua de Sinais; se os professores viam relação entre este ensino e o empoderamento dos alunos; o que professores de outras disciplinas achavam dos professores dessa disciplina (LS; qual a relação entre identidade surda e currículo de língua de sinais. A análise das entrevistas mostrou que os professores reconhecem a importância deste ensino e sua relevância para as identidades surdas, mas relataram dificuldades como: insuficiente participação dos alunos na comunidade surda; isolamento dos professores surdos em algumas escolas, sem terem com quem trocar idéias; discriminação em relação aos professores de LIBRAS; insegurança de alguns professores sobre o currículo trabalhado. A análise mostrou aspectos positivos, mas também mostrou que ainda há muito o que fazer no ensino escolarizado de LIBRAS.

  19. Internet Teaching By Style: Profiling the On-line Professor

    Directory of Open Access Journals (Sweden)

    Sharon Strand

    2000-01-01

    Full Text Available The goal of this article is to offer the results of a pilot study which examined the personality type and teaching style preferences of faculty who elected to teach an on-line course. The article will present a description of personality assessments, including the Myers-Briggs Type Indicator (MBTI and Anthony Gregorc's Transaction Ability Inventory used to determine teaching tendencies and styles. In addition, a structured written questionnaire developed by the researchers was used to assess teacher satisfaction with worldwide web-based instruction. Utilizing the results of these psychological assessments, a preliminary analysis of the personal characteristics of college professors who chose to teach on line will be presented. This pilot study found that some preferred teaching styles may be more compatible with the dynamics of distance learning formats. By determining successful teaching styles for on-line courses, we can develop more effective faculty development programs to assist others in successfully transitioning into the cyber-teaching and learning environment.

  20. Professor Toshio Ito: a clairvoyant in pericyte biology.

    Science.gov (United States)

    Suematsu, M; Aiso, S

    2001-06-01

    Ito cells are liver-specific pericytes which were first described as Fett Speicherung Zellen, the fat-storing cells encircling outside sinusoidal endothelial cells, in 1951 by the late professor Toshio Ito. His pioneering approaches for morphological characterization of the cells stimulate investigators to further examine their functional roles in liver homeostasis: a body of evidence has been accumulated in recent years showing that the cells play a crucial role in storage and delivery of vitamin A, regulation of sinusoidal tone and local blood supply, and tissue repair and fibrosis. It is now widely accepted that microvascular pericytes including Ito cells serve as a key player that controls angiogenesis. Furthermore, recent studies support a concept that Ito cells constitutes a bridging apparatus mediating bidirectional metabolic interactions between sinusoids and hepatocytes, utilizing prostanoids and/or gaseous mediators such as nitric oxide and carbon monoxide as signaling molecules. This article reviews researches on this liver-specific pericyte and its leading roles in recent development of pericyte biology.

  1. DEVELOPMENT OF A VIRTUAL FORUM FOR PHYSICS PROFESSORS

    Directory of Open Access Journals (Sweden)

    R. Castañeda

    2003-09-01

    Full Text Available Nowadays sophisticated authoring tools allow developers to design and develop sophisticated web sites, in a fraction of the time that was required a few years ago. These tools have also allowed non-experienced users to create their own web pages, contributing in that sense to the expansion of the Internet. Nevertheless, while most of these sites are technically correct (links work fine, they too often result to be very difficult, and sometimes impossible, to be used. Our position is that the use of development tools is not sufficient. The development of web sites, as any other software requires of a methodology that maximizes the chances of the project success. In this paper we present a user-centered methodology employed in the development of a web site that will help physics professors of high school to communicate among them, and to share their experiences. The characteristics of the methodology and its different stages are detailed in this paper and the final product is presented as well as future works.

  2. `Dear Professor Dyson': Twenty years of correspondence between Freeman Dyson and undergraduate students

    Science.gov (United States)

    Neuenschwander, Dwight E.

    2014-03-01

    For twenty years the students in my "Science, Technology, and Society" course, where we use Disturbing the Universe as a textbook, have corresponded with Professor Dyson. That someone of Professor Dyson's standing consistently makes a priority of promptly answering the letters of undergraduate students from all academic majors, and does so with grace and kindness, insight and wisdom, offers a personal glimpse into his character and integrity. On behalf of my students, and as a way of publicly thanking Professor Dyson for participating in our course conversations, I am honored to share samples of our correspondence with him over the years, including student reflections on his involvement in their education.

  3. `DEAR Professor DYSON:' Twenty Years of Correspondence Between Freeman Dyson and Undergraduate Students

    Science.gov (United States)

    Neuenschwander, Dwight E.

    2014-04-01

    For twenty years the students in my "Science, Technology, and Society" course, where we use Disturbing the Universe as a textbook, have corresponded with Professor Dyson. That someone of Professor Dyson's standing consistently makes a priority of promptly answering the letters of undergraduate students from all academic majors, and does so with grace and kindness, insight and wisdom, offers a personal glimpse into his character and integrity. On behalf of my students, and as a way of publicly thanking Professor Dyson for participating in our course conversations, I am honored to share samples of our correspondence with him over the years, including student reflections on his involvement in their education.

  4. An Interview with Professor Melquíades de Dios Leyva, December 2008

    Science.gov (United States)

    Arias de Fuentes, Olimpia

    When writing about the history of physics in Cuba, this remarkable professor of quantum mechanics must be mentioned, for he embodies a most genuine example of the turn taken by national educational policy after 1959: Education for all, at all levels, with no discrimination or elitism. The following is an interview granted by Dr. Melquíades de Dios Leyva, Outstanding Full Professor of the Physics Faculty of the University of Havana, to Dr. Olimpia Arias de Fuentes, Associate Professor at the same, and Senior Researcher of the Institute of Materials Science and Technology (IMRE) of the University of Havana.

  5. Efeito pai professor: o impacto da profissão docente na vida escolar dos filhos

    OpenAIRE

    Nogueira, Marlice de Oliveira e

    2013-01-01

    Este artigo pretende divulgar os resultados de uma pesquisa de doutorado recentemente finalizada que investigou as práticas educativas de famílias em que pelo menos um dos progenitores exercia a profissão de professor. A pesquisa buscou identificar, analisar e discutir as múltiplas práticas educativas e estratégias de escolarização que pais professores desenvolvem no quadro da vida escolar de seus filhos. Os resultados obtidos mostram que, de um modo geral, os pais professores se mobilizam in...

  6. Prvi koraki utemeljevanja posebne vloge členka fu 夫 v stavi klasične kitajščine: Analiza besedil mojstra Han Feizija 韩非子

    Directory of Open Access Journals (Sweden)

    Jan VRHOVSKI

    2012-12-01

    Full Text Available Despite the prevailing academic opinion regarding the use of the particle fu 夫 in Classical Chinese syntax, this article proposes a new interpretation of fu 夫 as an introductory particle expressing a special kind of generalizing force that results in a shift of the truth-value of a sentence to a higher level. Based on a thorough text analysis of Han Feizi 韩非子 it represents the first steps in unveiling the rhetorical use of fu 夫 and its systemic application in dialectical reasoning. By accounting for certain judgments of value made on an intuitive basis by a comparatively objective and consistent procedure, this paper hopes to shed new light on the characteristics of the special syntactic properties of Classical Chinese. This paper also represents the intuitive part of our investigation, forming an outline and laying a pattern for a following linguistic analysis.

  7. Buscando o caminho do meio: a "sala de espelhos" na construção de parcerias entre professores e formadores de professores de Ciências

    Directory of Open Access Journals (Sweden)

    Lenice Heloísa de Arruda Silva

    2000-01-01

    Full Text Available O presente trabalho enfoca a construção de uma parceria entre 35 professores e dois formadores de professores em um programa de formação continuada em Ciências. Segundo depoimentos dos participantes, a utilização e análise de algumas situações homólogas àquelas usualmente vivenciadas pelos professores no ensino de Ciências fez com que problematizassem e redimensionassem suas práticas pedagógicas. Tais situações exemplificam a estratégia "sala de espelhos", proposta por D. Schön, a qual configura-se como um importante recurso na construção de uma parceria intermediária àquela geralmente adotada pela academia, pautada na racionalidade técnica, e a configurada no contexto escolar.

  8. Interação professor-aluno em salas de aula de Ensino Médio

    OpenAIRE

    Angelica Teixeira Gomes

    2011-01-01

    Estudos recentes apontam a importância das interações entre professores e alunos no contexto escolar de forma geral. Este trabalho buscou investigar a percepção de alunos do Ensino Médio acerca da interação com seus professores na sala de aula, como percebem o relacionamento com o professor, o que esperam do professor, o que lhes agrada/desagrada na interação com os docentes. Além disso, analisou os modos de interação entre professores e alunos tais como acontecem no cotidiano institucional. ...

  9. Fußball und Identität in Israel - Die Rolle der Medien im Kontext politisch-kultureller Identitätsbildung und Ausgrenzungsprozesse

    Directory of Open Access Journals (Sweden)

    Michael Schuster

    2010-03-01

    Full Text Available Eine gängige These besagt, dass sich im Sport gesellschaftliche Konflikte widerspiegeln. Insbesondere dem Fußball wird unterstellt, eine Arena zur Artikulation und Repräsentation exklusiver Identität nationaler Minderheiten zu bieten. Der vorliegende Artikel widmet sich dem Thema der politisch-kulturellen Identitätsbildung in fragmentierten Gesellschaften. Am Beispiel der arabischen Minderheit in Israel wird dargestellt, dass unter bestimmten gesellschaftlichen Konstellationen der Fußball als Element der Popularkultur dem Staat auch als Mittel der Unterdrückung eines nationalen Minderheitenbewusstseins dienen kann. Unter Zuhilfenahme der Hegemonietheorie Antonio Gramscis kann das Entstehen einer pro-israelischen Identität der arabischen Minderheit - in Abgrenzung zu einer eigenen, arabischen oder widerständigen Identität - im Kontext des Fußballs rekonstruiert werden. Zu diesem Zweck wird aufgezeigt, welche Bedeutungs- und Definitionsmacht hebräische und arabische Sportmedien als Akteure divergierender Bedeutungszuschreibungen in dem Konfliktfeld der Herausbildung politisch-kultureller Identitäten besitzen und ihrerseits vorherrschende Integrations- und Dominanzprozesse beeinflussen. It is a widespread/popular thesis that sports are a useful means to display social conflicts; in particular it is argued that football offers a platform for the articulation and representation of the identity of ethnic/national/(cultural minorities. This article focuses on the construction of identity in fragmented societies with the help of politics and culture. With the example of the Arab minority in Israel it is portrayed here, that under particular social circumstances football can be used as an element of popular culture to repress the cultural and political identity of minorities. Gramsci's theory of hegemony explains the construction of a pro-Israel identity among the Arab minority which differs from their own Arab identity. It is shown here to

  10. A randomised placebo-exercise controlled trial of Kung Fu training for improvements in body composition in overweight/obese adolescents: the "Martial Fitness" study.

    Science.gov (United States)

    Tsang, Tracey W; Kohn, Michael; Chow, Chin Moi; Singh, M Fiatarone

    2009-01-01

    The purpose of the study was to investigate if Chinese martial arts (Kung Fu, KF) might be effective for improving body composition, as well as being an appealing form of physical activity for inexperienced, sedentary, overweight/obese adolescents. Twenty subjects (age: 13.3 ± 1.8 y; BMI percentile: 98.6(86.5 - 99.8); 60% girls) were randomly-assigned to the supervised KF or placebo (Tai Chi, TC) control group 3 d.wk(-1) for 6 months. We assessed body composition, including total and regional fat and lean mass, total and regional bone mineral density (BMD), percent lean and fat mass, body mass index and waist circumference, at baseline and after 6 months of training using anthropometry and dual-energy X-ray absorptiometry (DXA). Habitual physical activity and dietary intake were recorded as covariates via self-report at each time-point. As expected due to natural growth, significant increases in height, weight, total and lumbar BMD, and lean mass were seen in the cohort over time, with a trend for increased whole body fat mass, with no difference between groups. By contrast, percent fat and android fat mass via DXA did not increase in either group over time. The absence of a similar expected increase in central adiposity over 6 months could indicate a positive effect of participation in both programs on the metabolically critical abdominal adiposity in this cohort. Further research in this area is warranted to determine ways to increase uptake and compliance, and to see if longer-term martial arts training not only maintains, but improves abdominal fat mass and related metabolic health indices in overweight/ obese adolescents. Key pointsParticipation in our martial arts trial attenuated the increases in body fat mass expected due to growth in our overweight/obese adolescent group.All subjects allocated to the Kung Fu intervention were satisfied with their Kung Fu training, in contrast to our placebo-exercise (Tai Chi) subjects, suggesting that this form of

  11. Ser um professor pesquisador/Be a researcher-teacher

    Directory of Open Access Journals (Sweden)

    Edna Scola Klein

    2006-01-01

    Full Text Available O Projeto "ESCOLA SINGULAR: AÇÕES PLURAIS", realizado na nossa unidade escolar, tem trazido a discussão e a reflexão para as nossas reuniões, compreensão de atitudes dos adolescentes e nossas enquanto profissionais. Trabalhar em grupo e viver com as diversidades é um grande desafio e também uma grande aprendizagem. Esta diversidade ocorre entre os colegas de trabalho e na própria sala de aula. Refletir sobre nossas ações nos traz a figura do professor-pesquisador. Realizamos diversas atividades na escola que trouxeram a todos uma maior participação nos espaços escolares, contato com a arte, com a pesquisa, com a observação. Estes processos ocorreram entre os alunos e com a equipe docente também. Participo de reuniões semanais, com os professores de 5ª a 8ª séries para trocas de idéias, estudo e discussões de textos e temas. Ouvir e participar das discussões com os diversos profissionais do Projeto sobre as teorias de aprendizagem, diversidades de estratégias utilizadas nas aulas ou formas de aquisição de conhecimento foi muito importante para o nosso trabalho. Interdisciplinaridade é o tema do subgrupo que participo e inicialmente o interessante do trabalho em grupo é realmente o fortalecimento de cada pessoa e a percepção de uma atitude interdisciplinar. Debatemos os conceitos de Interdisciplinaridade e planejamos algumas ações de forma interdisciplinar para aplicá-las com os alunos. The “Singular school: Plural actions” project, created at our school unity, has been brought the discussion and reflection to our reunions, comprehension of teenage and ourselves attitudes, while professionals. Work in group and to live with these difficulties it´s a great challenge and a great learning. This diversity it happens among the co-workers and at the classroom itself. Reflect about our actions bring us the image of the researcher-teacher. We did many activities at the school that brought to all a bigger

  12. From the interview with professor Jan Derksen: "There are no emotions in brain images"

    NARCIS (Netherlands)

    Derksen, J.J.L.

    2017-01-01

    We present an interview of professor Jan Derksen (Radboud Universiteit Nijmegen) about the importance of psychological theories of mental processes. He also considered the dangers of narrow biological interpretations in psychological research and practice based solely on neurobiological mechanisms

  13. Homage to the professor Domingo Plácido Suárez

    Directory of Open Access Journals (Sweden)

    Miriam VALDÉS GUÍA

    2011-03-01

    Full Text Available He retired professor at the UCM, Domingo Placido, who has worked since its inception, as usual, with his good «task» of History, the journal «Studia Historica: Ancient History»

  14. History of Higher Education: Educational Reform and the Emergence of the Nursing Professorate.

    Science.gov (United States)

    Ruby, Jane

    1999-01-01

    In the late 19th century, visionary leaders pursued liberal education for nurses, moving nursing education from hospitals to universities. The nursing professorate might never have developed had nursing education remained under the jurisdiction of hospitals. (SK)

  15. Experimental Effects of Student Evaluations Coupled with Collaborative Consultation on College Professors' Instructional Skills

    NARCIS (Netherlands)

    Knol, M.H.; in 't Veld, R.; Vorst, H.C.M.; van Driel, J.H.; Mellenbergh, G.J.

    2013-01-01

    This experimental study concerned the effects of repeated students’ evaluations of teaching coupled with collaborative consultation on professors’ instructional skills. Twenty-five psychology professors from a Dutch university were randomly assigned to either a control group or an experimental

  16. Professor Robert D. Putnam : sotsiaalse kapitali suurendamiseks tuleb luua sildu / Dagmar Lamp

    Index Scriptorium Estoniae

    Lamp, Dagmar

    2006-01-01

    26. mail 2006. a. Tallinnas Avatud Ühiskonna XI Foorumil esines Harvardi ülikooli professor Robert D. Putnam ettekandega sotsiaalsest, füüsilisest ja inimkapitalist ning sotsiaalsete võrgustike väärtusest

  17. College Students’ Perceptions of Professor/Instructor Bullying: Questionnaire Development and Psychometric Properties

    Science.gov (United States)

    Marraccini, Marisa E.; Weyandt, Lisa L.; Rossi, Joseph S.

    2016-01-01

    Objective This study developed and examined the psychometric properties of a newly formed measure designed to assess professor/instructor bullying, as well as teacher bullying occurring prior to college. Additionally, prevalence of instructor bullying and characteristics related to victims of instructor bullying were examined. Participants Participants were 337 college students recruited in 2012 from a northeastern university. Methods An online questionnaire was administered to college students. A split-half, cross-validation approach was employed for measurement development. Results The measure demonstrated strong criterion validity and internal consistency. Approximately half of students reported witnessing professor/instructor bullying and 18% reported being bullied by a professor/instructor. Report of teacher bullying occurring prior to college was related to professor/instructor bullying in college, and sex was a moderating variable. Conclusion College students perceive instructor bullying as occurring but may not know how to properly address it. Prevention efforts should be made by university administrators, faculty and staff. PMID:26151235

  18. University of Chicago professor to speak on race, wealth, and public policy

    OpenAIRE

    Ho, Sookhan

    2010-01-01

    University of Chicago professor Kerwin Charles will give a lecture, "Race and Wealth: Income, Expenditure, and Public Policy," on Thursday, March 18, 2-3 p.m., at Alumni Assembly Hall, Inn at Virginia Tech.

  19. Digitaalse arengu eestvedaja Rootsis - digitšempion professor Jan Gulliksen / Tauno Otto

    Index Scriptorium Estoniae

    Otto, Tauno, 1967-

    2016-01-01

    Tallinna tehnikaülikoolis pidas 22. aprillil avaliku loengu Rootsi kuningliku tehnikaülikooli dekaan, professor Jan Gulliksen. Loengu teema oli, kuidas Rootsi edendab digitaliseerimist nii hariduses kui ka tööstuses

  20. Professor Ülo Ugaste valiti Soome Teadusliku Seltsi välisliikmeks / Ain Ainsaar

    Index Scriptorium Estoniae

    Ainsaar, Ain

    2000-01-01

    Soome Teaduslik Selts (Societas Scientiarum Fennica) matemaatika ja füüsika sektsioon valis TPÜ loodusteaduste osakonna rakendusfüüsika õppetooli juhataja professor Ülo Ugaste oma välisliikmeks

  1. On the Eightieth Birthday of Professor Erwin Stein, March 7, 1983.

    Science.gov (United States)

    Avenarius, Hermann

    1985-01-01

    The contributions that Professor Erwin Stein has made to German education are discussed. For example, he played a crucial role in the founding of the School for International Pedagogical Research. (RM)

  2. Physical activities practicing among scholar professors: focus on their quality of life

    Directory of Open Access Journals (Sweden)

    Jaqueline Dias

    2017-10-01

    Full Text Available Abstract Objective: To investigate the practice of physical activity among scholar professors focusing on their quality of life. Methods: A cross-sectional study was carried out with 121 professors at one of the campuses of a state university in the State of Paraná, using a questionnaire created by Baecke and adapted for the study. Results: The analyzed group presented a level of inadequate physical activity of 54.4%, with mean body mass of 26.20, considered overweight. Conclusion: The study indicated that professors do not practice physical activity at the level recommended by the World Health Organization; therefore, they are, for the most part, sedentary and have complaints of anxiety. It is advisable to carry out actions aimed at the health of the professors, directed to the modification in the lifestyle, with regular practice of physical activities and balanced diet, for the improvement of the quality of life.

  3. Professor Glyn O. Phillip's legacy within the IAEA programme on radiation and tissue banking.

    Science.gov (United States)

    Morales Pedraza, Jorge

    2017-08-19

    Professor Phillips began his involvement in the implementation of this important IAEA programme, insisting that there were advantages to be gained by using the ionizing radiation technique to sterilize human and animal tissues, based on the IAEA experience gained in the sterilization of medical products. The outcome of the implementation of the IAEA programme on radiation and tissue banking demonstrated that Professor Phillips was right in his opinion.

  4. Subjective well-being and time use of brazilian PhD professors

    Directory of Open Access Journals (Sweden)

    Maiana Farias Oliveira Nunes

    2014-12-01

    Full Text Available The university professor suffers high pressure to achieve productivity and performs under work conditions that are not always satisfactory. This study seeks to analyze the subjective well-being, the time-use strategies, and the satisfaction with their use of time of PhD-holding professors with and without productivity grants from the National Council for Scientific and Technological Development (CNPq. A total of 83 professors participated in the study (48 with productivity grants, with an average age of 50 years. A total of 89% of participants were from public institutions. The majority of the participants exhibited high levels of negative affect and low-average levels of satisfaction with their use of time. There was no difference in the subjective well-being or in the satisfaction with the use of time when comparing professors who had received a CNPq grant with professors who had not received a CNPq grant. The most important reason for dissatisfaction with the use of time was an excess of work, whereas peer recognition was the primary achievement obtained with the work. How work demands and conditions influence the well-being of the professors is discussed in this study.

  5. [Learning styles in medical residents and their professors of a pediatric hospital.

    Science.gov (United States)

    Juárez-Muñoz, Irina Elizabeth; Gómez-Negrete, Alonso; Varela-Ruiz, Margarita; Mejía-Aranguré, Juan Manuel; Mercado-Arellano, José Agustín; Sciandra-Rico, Martha Minerva; Matute-González, Mario Manuel

    2013-01-01

    Background: the learning styles are cognitive, emotional, and psychological characteristics, which function as relatively stable indicators of how teachers and students perceive, interact, and respond to their learning environments. Knowing students' styles allows teachers to have tools to improve medical education. Our objective was to identify learning styles in pediatric residents and professors from a pediatric hospital. Methods: a learning styles questionnaire was applied to residents and theirs professors; data was analyzed in SPSS 12 software. Results: the dominant learning style in pediatric residents was reflexive and for professors was theoretical. There wasn't any difference between sexes or between medical or surgical specialities. There was more correlation between professors and residents when there was an increase in training time. Conclusions: the learning styles between professors and residents are different, especially at the beginning of the medical specialty courses; that's why it is necessary to realize a confrontation between the students' learning styles and teaching methods used by professors to improve significant learning. To know learning styles gives residents an important alternative to find a better study strategy.

  6. HABILIDADES SOCIAIS DE PROFESSORES E NÃO PROFESSORES: COMPARANDO ÁREAS DE ATUAÇÃO/ SOCIAL ABILITIES OF PROFESSORS AND NON-PROFESSORS: COMPARISON OF ACTION AREAS/ HABILIDADES SOCIALES DE PROFESORES Y NO PROFESORES: UNA COMPARACIÓN ENTRE ÁREAS DE ACTUACIÓN

    Directory of Open Access Journals (Sweden)

    Adriana Benevides Soares

    2011-12-01

    Full Text Available O objetivo deste trabalho foi comparar os repertórios de habilidades sociais dos profissionais professores e não professores, e comparar as áreas de atuação desses profissionais. Participaram da amostra 527 profissionais de ambos os sexos. Foi aplicado o Inventário de Habilidades Sociais definido por Del Prette (2001. Os principais resultados foram os seguintes: não houve diferenças de habilidades sociais entre professores relativos à área de atuação. Quanto aos profissionais não professores os mais habilidosos são os das ciencias agrárias para o fator de enfrentamento com risco (Fator 1, e para os fatores conversacao e desenvoltura social (Fator 3 e ainda para o de auto-exposicao a desconhecidos ou a situacoes novas (Fator 4 os mais habilidosos foram os das ciencias humanas. Entre professores e não profesores encontrou-se que os profissionais das ciencias agrárias são mais habilidosos que os demais no Fator 1. Nos Fatores 2 (habilidade de auto-afirmacao na expressao do afeto positivo, 3, 4 e IHS total são os professores de ciências humanas os que têm melhor repertório em IHS.

  7. Biology Professors' and Teachers' Positions Regarding Biological Evolution and Evolution Education in a Middle Eastern Society

    Science.gov (United States)

    BouJaoude, Saouma; Asghar, Anila; Wiles, Jason R.; Jaber, Lama; Sarieddine, Diana; Alters, Brian

    2011-05-01

    This study investigated three questions: (1) What are Lebanese secondary school (Grade 9-12) biology teachers' and university biology professors' positions regarding biological evolution?, (2) How do participants' religious affiliations relate to their positions about evolutionary science?, and (3) What are participants' positions regarding evolution education? Participants were 20 secondary school biology teachers and seven university biology professors. Seventy percent of the teachers and 60% of the professors were Muslim. Data came from semi-structured interviews with participants. Results showed that nine (Christian or Muslim Druze) teachers accepted the theory, five (four Muslim) rejected it because it contradicted religious beliefs, and three (Muslim) reinterpreted it because evolution did not include humans. Teachers who rejected or reinterpreted the evolutionary theory said that it should not be taught (three), evolution and creationism should be given equal time (two), or students should be allowed to take their own stand. Two professors indicated that they taught evolution explicitly and five said that they integrated it in other biology content. One Muslim professor said that she stressed 'the role of God in creation during instruction on evolution'. It seems that years of studying and teaching biology have not had a transformative effect on how a number of teachers and professors think about evolution.

  8. Uptake of 5-fluorouracil (5-FU) in peritoneal metastases in relation to the route of drug administration and tumour debulking surgery. an autoradiographic study in the rat.

    Science.gov (United States)

    Mahteme, H; Larsson, B; Sundin, A; Khamis, H; Graf, W

    2004-01-01

    Patients with peritoneal metastases from colorectal cancer have a poor prognosis. Aggressive treatment by debulking surgery and intraperitoneal (i.p.) chemotherapy has been suggested as an alternative therapy. However, the drug penetrance into the tumour in relation to the administration route and surgical reduction of the tumour is not well known. We compared locoregional administration with intravenous (i.v.) injection. Thirty-four in-bred rats with peritoneal metastases were randomly allocated into eight groups and injected with 14C-labelled 5-fluorouracil (5-FU) either through the i.v. or i.p. route, with or without a preceding tumour debulking, and were sacrificed after 2 or 8 h. Tumour radioactivity was visualised by autoradiography and quantified by a computer-based image analysis. After 8 h, 19 debulked and i.p.-injected tumours had a higher drug uptake, 63.2+/-28 (mean+/-standard deviation (SD)) kBq/g than 62 native i.p.-injected tumours (32.8+/-14) or 22 debulked and i.v.-injected tumours (18.5+/-18, P=0.002). After 8 h, 9 small tumours (/=median 571 pixels), 16 debulked and i.p.-injected tumours had a higher radioactivity (drug uptake) (150.7+/-63) at 2 h than 49 i.p.-injected native tumours (48.5+/-59) or 11 reduced and i.v.-injected tumours (19.9+/-13, P=0.03). At 8 h, 10 debulked and i.p.-injected tumours had a higher drug uptake (50.3+/-24) than 33 native and i.p.-injected (30.8+/-10) or 14 debulked and i.v.-injected tumours (16.0+/-19, P=0.001). These results indicate that a debulking procedure and locoregional treatment of peritoneal metastases is associated with an increased level of 5-FU in the tumours.

  9. YiQiFuMai powder injection ameliorates blood–brain barrier dysfunction and brain edema after focal cerebral ischemia–reperfusion injury in mice

    Directory of Open Access Journals (Sweden)

    Cao GS

    2016-01-01

    Full Text Available Guosheng Cao, Xinyi Ye, Yingqiong Xu, Mingzhu Yin, Honglin Chen, Junping Kou, Boyang Yu Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Department of Complex Prescription of TCM, China Pharmaceutical University, Nanjing, People’s Republic of China Abstract: YiQiFuMai powder injection (YQFM is a modern preparation derived from the traditional Chinese medicine Sheng-Mai-San. YQFM is widely used in clinical practice in the People’s Republic of China, mainly for the treatment of microcirculatory disturbance-related diseases. However, little is known about its role in animals with ischemic stroke. The aim of this study was to examine the effect of YQFM on brain edema and blood–brain barrier (BBB dysfunction induced by cerebral ischemia–reperfusion (I/R injury. Male C57BL/6J mice underwent right middle cerebral artery occlusion for 1 hour with a subsequent 24-hour reperfusion to produce I/R injury. YQFM (three doses: 0.336, 0.671, and 1.342 g/kg was then given intraperitoneally (IP. The results demonstrated that YQFM significantly decreased infarct size, improved neurological deficits, reduced brain water content, and increased cerebral blood flow after I/R injury. 18F-fluorodeoxyglucose micro-positron emission tomography imaging and hematoxylin and eosin staining results indicated that YQFM is able to ameliorate brain metabolism and histopathological damage after I/R. Moreover, YQFM administration reduced BBB leakage and upregulated the expression of zona occludens-1 (ZO-1 and occludin, which was confirmed by Evans Blue extravasation, Western blotting, and immunofluorescence assay. Our findings suggest that YQFM provides protection against focal cerebral I/R injury in mice, possibly by improving BBB dysfunction via upregulation of the expression of tight junction proteins. Keywords: YiQiFuMai powder injection, YQFM, ischemic stroke, blood–brain barrier, microvascular permeability, tight junctions

  10. Association between ERCC1 and TS mRNA levels and disease free survival in colorectal cancer patients receiving oxaliplatin and fluorouracil (5-FU) adjuvant chemotherapy.

    Science.gov (United States)

    Li, Sheng; Zhu, Liangjun; Yao, Li; Xia, Lei; Pan, Liangxi

    2014-08-29

    Aim was to explore the association of ERCC1 and TS mRNA levels with the disease free survival (DFS) in Chinese colorectal cancer (CRC) patients receiving oxaliplatin and 5-FU based adjuvant chemotherapy. Total 112 Chinese stage II-III CRC patients were respectively treated by four different chemotherapy regimens after curative operation. The TS and ERCC1 mRNA levels in primary tumor were measured by real-time RT-PCR. Kaplan-Meier curves and log-rank tests were used for DFS analysis. The Cox proportional hazards model was used for prognostic analysis. In univariate analysis, the hazard ratio (HR) for the mRNA expression levels of TS and ERCC1 (logTS: HR = 0.820, 95% CI = 0.600 - 1.117, P = 0.210; logERCC1: HR = 1.054, 95% CI = 0.852 - 1.304, P = 0.638) indicated no significant association of DFS with the TS and ERCC1 mRNA levels. In multivariate analyses, tumor stage (IIIc: reference, P = 0.083; IIb: HR = 0.240, 95% CI = 0.080 - 0.724, P = 0.011; IIc: HR TS and ERCC1 mRNA levels were not significantly associated with the DFS (TS: P = 0.264; ERCC1: P = 0.484). The mRNA expression of ERCC1 and TS were not applicable to predict the DFS of Chinese stage II-III CRC patients receiving 5-FU and oxaliplatin based adjuvant chemotherapy.

  11. The first professor headed the department of obstetrics and gynecology of Saratov State Medical University—professor N.M. Kakushkin (to the 150th anniversary

    Directory of Open Access Journals (Sweden)

    Zavyalov A.I.

    2013-06-01

    Full Text Available The article presents the data concerned biography of professor N. M. Kakushkin. His scientific and practical contribution to the development of native medical science and organization of department of Obstetrics and Gynecology in Imperial Nicolas University (Saratov have been outlined in the article.

  12. CD4 RAT X RAT AND MOUSE X RAT T-CELL HYBRIDOMAS PRODUCED BY FUSION OF ESTABLISHED T-CELL LINES AND CLONES TO W/FU (C58NT)D

    NARCIS (Netherlands)

    BOOTS, AMH; VANLIEROP, MJ; WAUBEN, MHM; VANKOOTEN, PJS; HENSEN, EJ; VANEDEN, W; Boots, Annemieke

    1991-01-01

    Previously, fusion of established T cell lines or clones has been claimed to be difficult. We now report our experiences in the fusion of both long term cultures of rat T cell clones and mouse T cell lines to rat W/Fu (C58NT)D. Upon fusion of rat T cell clones the hybrids obtained expressed antigen

  13. Estilos motivacionais de professores: preferência por controle ou por autonomia

    Directory of Open Access Journals (Sweden)

    Amélia Carolina Terra Alves Machado

    Full Text Available A motivação é fundamental para o envolvimento dos estudantes na escola. Para a teoria da autodeterminação, o estilo motivacional do professor, que pode controlar ou promover a autonomia, contribui para fomentar a ocorrência de tipos qualitativamente diferenciados de motivação. Neste estudo, de natureza exploratória, foram analisadas as interações entre dois professores e seus alunos. A amostra foi composta de acordo com o desempenho de 39 professores na avaliação do estilo motivacional, mediante a aplicação de um instrumento de autorrelato, problemas na escola. Desse total, dois professores, um com estilo motivacional promotor de autonomia e outro com uma orientação para o controle, tiveram suas aulas observadas em sete sessões, com o objetivo de levantar dados para a elaboração de um protocolo que continha categorias de interações. Foram então realizadas outras sete sessões de observação. Os resultados indicaram que, apesar de terem sido encontradas diferenças entre os desempenhos na avaliação do estilo motivacional, os professores interagiram com seus alunos de modo preferencialmente controlador. No entanto, o professor que promovia a autonomia interagiu de modo menos controlador no gerenciamento do tempo destinado para a realização das atividades em classe quando comparado ao professor controlador, além de oferecer feedback informativo. As implicações educacionais dos resultados são analisadas.

  14. Professor Octávio de Silveira: the pioneer of neurology in the State of Paraná Professor Octávio da Silveira: o pioneiro da neurologia no Estado do Paraná

    Directory of Open Access Journals (Sweden)

    Hélio A.G. Teive

    2008-09-01

    Full Text Available The author gives a brief overview of the career of Professor Octávio da Silveira, the first neurologist and professor of neurology in the State of Paraná, as well as the first full professor of clinical neurology in the Federal University of Paraná.O autor apresenta de forma resumida os dados históricos que definem o professor Octávio da Silveira como o primeiro neurologista e professor de neurologia do Estado do Paraná, além do título de primeiro professor catedrático da clínica neurológica da Universidade Federal do Paraná.

  15. Translation and Creative Writing: An Interview with Professor Margaret Rogers

    Directory of Open Access Journals (Sweden)

    Ruzbeh Babaee

    2016-01-01

    Full Text Available Introduction This interview was conducted with Emerita Professor Margaret Rogers with the aim of providing a brief but informative summary of the relationship between translation and creative writing. Emerita Professor Rogers is in the Centre for Translation Studies, School of English and Languages, University of Surrey, UK. She is also the founder of Terminology Network at the Institute of Translation and Interpreting in the UK. Professor Rogers introduced creative writing into the translation curriculum some 10 years ago at her own university.   The Interview   RB[1]: Do you believe in a theory of translation? MR[2]: There are many ways of trying to understand and, where we can, explain translation in all its guises, loci and times. To talk about ‘a theory’ in this context doesn’t help much. There are many different approaches to the academic study of translation: rather simply put, the particular approach which we choose to adopt may depend on our object of study (e.g. literary translation or specialised translation, what we want to find out about this (e.g. are we interested in product or process, in a historical or contemporary perspective, what resources we have available (e.g. a fully funded research team or a solo effort and so on. Many projects are interdisciplinary—this has long been recognised—and translation scholars are becoming much more resourceful in identifying, adopting and adapting relevant approaches from intersecting disciplines such as comparative literature, cultural studies, history, linguistics, philosophy, psychology and sociology. Some scholars are now advocating a problem-based approach. In any research project it is important to establish how the problem/phenomenon/issue which has been identified as the focus of the study can be tackled. For this, in an empirical study a method is crucial: in translation studies this is rarely something that can be picked off the shelf and is often a contribution to the

  16. Impact of technology-infused interactive learning environments on college professors' instructional decisions and practices

    Science.gov (United States)

    Kuda Malwathumullage, Chamathca Priyanwada

    Recent advancements in instructional technology and interactive learning space designs have transformed how undergraduate classrooms are envisioned and conducted today. Large number of research studies have documented the impact of instructional technology and interactive learning spaces on elevated student learning gains, positive attitudes, and increased student engagement in undergraduate classrooms across nation. These research findings combined with the movement towards student-centered instructional strategies have motivated college professors to explore the unfamiliar territories of instructional technology and interactive learning spaces. Only a limited number of research studies that explored college professors' perspective on instructional technology and interactive learning space use in undergraduate classrooms exist in the education research literature. Since college professors are an essential factor in undergraduate students' academic success, investigating how college professors perceive and utilize instructional technology and interactive learning environments can provide insights into designing effective professional development programs for college professors across undergraduate institutions. Therefore, the purpose of this study was to investigate college professors' pedagogical reasoning behind incorporating different types of instructional technologies and teaching strategies to foster student learning in technology-infused interactive learning environments. Furthermore, this study explored the extent to which college professors' instructional decisions and practices are affected by teaching in an interactive learning space along with their overall perception of instructional technology and interactive learning spaces. Four college professors from a large public Midwestern university who taught undergraduate science courses in a classroom based on the 'SCALE-UP model' participated in this study. Major data sources included classroom

  17. Sensibilizar professores para o desenvolvimento de carreira dos alunos: relato de uma experiência

    Directory of Open Access Journals (Sweden)

    Íris M. Oliveira

    Full Text Available A literatura destaca a importância de realizar sessões de sensibilização dos professores para promover a sua influência positiva e intencional, enquanto docentes, nas trajetórias de carreira dos alunos. Este artigo relata uma experiência de realização de uma sessão de sensibilização junto a professores da educação básica de um agrupamento de escolas no noroeste de Portugal. Procurou-se esclarecer o conceito de desenvolvimento de carreira junto dos professores, conscientizá-los para o papel da escola no desenvolvimento de carreira dos alunos e estimular a dinamização de atividades promotoras desse processo. Apresenta-se a estrutura da sessão, as estratégias adotadas para alcançar os objetivos propostos e as reflexões partilhadas e debatidas pelos professores. As apreciações dos intervenientes quanto à sessão de sensibilização mostraram-se favoráveis. Esta experiência ilustra a importância de realizar sessões de sensibilização dos professores nesse domínio, as quais podem sustentar a promoção do desenvolvimento de carreira dos alunos, ao longo da escolaridade.

  18. A Tribute to Professor Steven L. Wechsler (1948-2016): The Man and the Scientist.

    Science.gov (United States)

    Nesburn, Anthony B; BenMohamed, Lbachir

    2017-01-01

    Professor Steven L. Wechsler, a world-renowned eye researcher and virologist, passed away unexpectedly on June 12, 2016 at the age of 68. Many scientists came to know Professor Wechsler as a gifted researcher in the field of ocular Herpes Simplex Virus (HSV-1) latency, reactivation, and pathogenesis. Professor Wechsler published over 150 peer-reviewed scientific papers during his career, pushing forward the frontiers of his field eye research. His colleagues would say, 'Steve literally wrote the book on herpes latency and reactivation.' He was the first to show that the HSV-1 latency-associated transcript (LAT) is essential for the HSV-1 high spontaneous reactivation phenotype and that LAT has anti-apoptosis activity. This discovery of LAT's anti-apoptosis activity, which is a key factor in how the LAT gene enhances reactivation, was published in Science in 2000 and created a new paradigm that greatly increased understanding of HSV-1 latency and reactivation. In collaboration with Professor Lbachir BenMohamed, an immunologist, they later demonstrated that LAT also acts as an immune evasion gene. He was a caring scientist who truly enjoyed working and sharing his experience and expertise with young researchers. He will be remembered as a significant pillar within scientific and ocular herpes research communities worldwide. Professor Wechsler's dedication to science, his compassionate character, and wonderful sense of humor were exemplary. We, who were his friends and colleagues, will mourn his passing deeply.

  19. Autoerotismo em sala de aula: o que pensam, como reagem e dizem fazer os professores?

    Directory of Open Access Journals (Sweden)

    Ricardo Desidério da Silva

    2014-02-01

    Full Text Available Percebendo-se a necessidade de uma discussão sobre a temática da sexualidade nas escolas e principalmente na formação dos docentes este estudo qualitativo investigou o relato de professores sobre o autoerotismo de seus alunos e alunas na sala de aula: o que pensam, como reagem e dizem fazer em sua prática docente. Participaram 9 professores, de ambos os sexos, que responderam a uma entrevista projetiva para posterior análise de conteúdo. Os resultados demonstram que os professores, apesar de considerarem importante este trabalho com seus alunos, manifestam dificuldade em falar sobre o tema, indicando inclusive que partem de suas concepções pessoais e não baseados em teorias, evidenciando assim, carência na sua formação para lidar com educação sexual na escola. Conclui-se que os professores ainda percebem a sexualidade a partir de mitos e tabus, especialmente sobre o autoerotismo e, nesse sentido, é importante investir na formação acadêmica de professores para que possam desenvolver de modo pedagógico, contínuo e sistemático, projetos de educação sexual na escola.

  20. Violência contra o professor nas representações sociais de docentes

    Directory of Open Access Journals (Sweden)

    Michelle Beltrão Soares

    2014-04-01

    Full Text Available http://dx.doi.org/10.5007/2175-795X.2014v32n1p333 Este artigo analisa as representações sociais de violência contra o professor no espaço de escolas públicas e privadas da Região Metropolitana do Recife, enfatizando as formas ou tipos de violência que afetam esse grupo profissional e o modo como os docentes lidam com o fenômeno. Tomou-se como referencial a Teoria das Representações Sociais, de Serge Moscovici, especialmente a Teoria do Núcleo Central, idealizada por Jean-Claude Abric. Participaram desta etapa da investigação 20 professores, sendo 10 de escolas públicas estaduais e 10 de escolas privadas. Foram realizadas entrevistas com esses professores através de pranchas indutoras, o material foi tratado a partir da Análise de Conteúdo. Os resultados do estudo indicam a dimensão prática das representações desses professores, ou seja, o modo como lidam com a violência contra si no interior da escola e sala de aula, expresso através das origens da violência contra o professor, das manifestações da violência contra ele e das atitudes de enfrentamento diante do fenômeno.

  1. A Formação de professores e os desafios de ensinar Ciências

    Directory of Open Access Journals (Sweden)

    Rita Helena Moreira Seixas

    2017-02-01

    Full Text Available Este artigo tem como objetivo refletir a respeito da formação inicial e/ou continuada dos professores, de seus desafios no ensino de Ciências e da forma como orientam seus alunos na construção do conhecimento científico. Aborda, sob a ótica de diferentes autores, o “saber” e o “saber fazer” dos professores de ciências, na ideia de aprendizagem como construção de conhecimentos. Aponta para o perfil do professor de ciências como aquele que fará a mediação do conhecimento para seus alunos objetivando a aprendizagem, tendo como desafio a utilização do conhecimento científico, das tecnologias educacionais e de estratégias didáticas que, muitas vezes, não estiveram presentes em sua formação. O ensino realizado por esse professor é visto, também, como aprendizagem para ele. Por fim, considera a necessidade de qualificação do professor, para que esse não fique à margem das necessidades escolares sem identificar suas insuficiências.

  2. Análise de um processo de reforma curricular vivenciado por professores formadores de nutricionistas

    Directory of Open Access Journals (Sweden)

    Ester de Queirós Costa

    2012-01-01

    Full Text Available Apresenta-se a análise de um processo de reforma curricular vivenciado por professores formadores de nutricionistas, iniciado em 2007. Objetiva-se contribuir para a discussão desse tema, ainda pouco explorado na literatura sobre formação de nutricionistas. Utilizou-se questionário, enviado, em 2009, por meio eletrônico. As questões seguiram orientação do Projeto Pedagógico do Curso. Participaram 23 professores responsáveis por 21 das 37 disciplinas do período avaliado. Revelou-se dificuldade docente para implantar metodologias ativas de ensino-aprendizagem e avaliar competências e habilidades; necessidade de reuniões periódicas dos gestores com professores para os ajustes necessários; professores empenhados em integrar conteúdos de diferentes disciplinas, teoria e prática na apresentação dos conteúdos e atividades de ensino com atividades de pesquisa. Debateram-se os resultados em reunião entre professores e estudantes da instituição pesquisada. O instrumento utilizado para a pesquisa se mostrou eficiente em apontar alguns dos obstáculos à reforma em curso e possíveis caminhos para transpô-los.

  3. Efeitos de uma intervenção sobre a topografia das habilidades sociais de professores

    Directory of Open Access Journals (Sweden)

    Almir Del Prette

    Full Text Available Examina a influência de um Programa de Desenvolvimento Interpessoal Profissional (PRODIP sobre aspectos topográficos do desempenho dos professores participantes. A intervenção objetivou desenvolver habilidades interpessoais do professor para o estabelecimento de condições interativas de ensino e foi realizada em doze sessões grupais de hora e meia cada, ao longo de dois meses. Os dados foram coletados através de filmagem de aulas pré e pós-intervenção. A topografia do desempenho dos professores foi descrita e avaliada em seus componentes não verbais, paralíngüísticos e mistos. Os resultados mostraram que todos os professores foram avaliados mais positivamente em vários componentes e que expressão facial, entonação, humor e entusiasmo foram objeto de "melhora" de praticamente todos os professores. Discutem-se esses resultados em relação aos objetivos do PRODIP e a outras questões de pesquisa.

  4. Competências de Professores: um fator competitivoCompetences of Professors: a competitive advantageCompetencias de Profesores: un factor competitivo

    Directory of Open Access Journals (Sweden)

    NASSIF, Vânia Maria Jorge

    2006-01-01

    Full Text Available RESUMOO objetivo dessa pesquisa foi o de verificar se a função Recursos Humanos das universidades privadas brasileiras estimula o desenvolvimento das competências do professor necessário para aumentar a competitividade das mesmas. A pesquisa qualitativa foi conduzida por meio de entrevistas com principais executivos das universidades. Uma outra pesquisa quantitativa foi desenvolvida por meio de um questionário fechado e auto-aplicável em 282 professores. A análise fatorial gerou algumas categorias de competências do professor. Os resultados revelaram que os professores reconhecem as competências necessárias para o exercício da docência, por outro lado, as universidades não percebem as ações e práticas de Recursos Humanos que facilitam o desenvolvimento dessas competências, propiciando um diferencial competitivo no ambiente acadêmico.ABSTRACTThe objective of this research was to verify if the Human Resources function in five Brazilian private universities stimulates the development and the exercise of the professor’s competences needed to raise their competitiveness. A qualitative research was conducted interviewing top management and Human Resources professionals of these universities. Another quantitative research was carried out using a self applied and closed questionnaire answered by 282 professors. A factor analysis identified 12 factors of professor’s competences that are viewed fundamental to exercise teacher’s function. Results revealed the professors recognize what are the competencies needed; however, the universities do not realize Human Resources actions facilitating them to develop these competences, promoting competitiveness in the academic market.RESUMENEsta investigación tuvo por finalidad verificar si la función Recursos Humanos de las universidades privadas brasileñas estimula el desarrollo de las competencias del profesor, necesario para aumentar la competitividad de las mismas. La investigaci

  5. Factors related to successful teaching by outstanding professors: an interpretive study.

    Science.gov (United States)

    Rossetti, Jeanette; Fox, Patricia G

    2009-01-01

    The purpose of this study was to identify and describe factors associated with successful university teaching within the cultural norms of a public university in the midwestern United States. An interpretive analysis was conducted using the educational philosophy and goal statements of 35 university professors who received Presidential Teaching Awards from the university. The professors' diverse disciplines included nursing, curriculum and instruction, accountancy, music, and political science. The authors offer nursing educators the opportunity to increase their confidence and effectiveness by "learning" from faculty members who have been recognized as exceptionally successful in teaching. Four main relevant themes associated with successful university teaching were identified: Presence, Promotion of Learning, Teachers as Learners, and Enthusiasm. The narratives of the professors helped define the meaning of successful teaching across disciplines and offer nursing faculty additional perspectives and experiences.

  6. 120 aastat professor Nikolai Maimi sünnist / Väino J. Riismandel

    Index Scriptorium Estoniae

    Riismandel, Väino, 1920-2017

    2004-01-01

    Professor Maim (26. veeb. 1884 Tartus - 10. jaan. 1976 USA) on lõpetanud Moskva ülikooli õigusteaduskonna (1909), Tartu Ülikooli riigiõiguse erialal (1915). Ta on töötanud Vene keisririigi siseministeeriumi teenistuse eriülesandeis ametnikuna, Eesti Vabriigis siseministri abina, välisministeeriumi juriskonsultina. Maimi peamiseks ülesandeks kujunes korraldamisjärgus oleva Tartu Ülikooli õigusteaduskonna organiseerimine. Peale 1944. aastal Eestist põgenemist oli ta õppejõuks Marburgi ülikoolis riigiteaduse ja riigiõiguse alal. LL.M. (George Washingtoni ülikool) Väino J. Riismandel on District of Columbia advokatuuri liige, oli professor Maimi õpilane ja töökaaslane Tartu Ülikoolis. Lisatud: professor Maimi trükis ilmunud tööd lk. 65

  7. [Perceptions of students, professors and users regarding the ethical dimension at odontology education].

    Science.gov (United States)

    Matos, Mariângela Silva de; Tenório, Robson

    2010-10-01

    The present work analyzes the perception that students, professors and users of the ambulatory have concerning the professional education in its ethical dimension, in two odontology course, a public and a private one from Bahia. It also aims to compare these perceptions with the observed ambulatory practice. With these purposes the following research instruments had been applied: questionnaires for 283 students, not-directive interviews with 32 professors and 36 users, and participatory observation in ambulatory practice in the two courses. The results show that (1) students and professors perceive the high stimulation of the ethic dimension, (2) students learn the basic concepts of bioethics theoretical knowledge, and (3) the majority of the users feel respected considering these principles. However, the observation of the ambulatory practice does not confirm all that perception results.

  8. Formação de professores: uma alternativa de dinâmica curricular

    Directory of Open Access Journals (Sweden)

    Oswaldo Alonso Rays

    2004-07-01

    Full Text Available No texto relata-se, em forma de síntese, uma alternativa de dinâmica curricular em andamento, elaborada entre os anos de 1999 e 2002, para a formação de professores. A referência epistemológica baseia-se nas inferências derivadas das Diretrizes Curriculares Nacionais para a Formação de Professores da Educação Básica e das Diretrizes Político-Pedagógicas do Centro Universitário Franciscano de Santa Maria (Unifra.Palavras-chave: Formação de Professores. Diretrizes Curriculares. Dinâmica Curricular.

  9. LIFE JOURNEY: MEDICAL AND SCIENTIFIC WORK OF PROFESSOR V.A. SOKOLOV

    Directory of Open Access Journals (Sweden)

    P. A. Ivanov

    2017-01-01

    Full Text Available The article is dedicated to doctor of medicine, professor V.A. Sokolov. In 2017 he celebrates his eightieth birthday. Professor V.A. .Sokolov is one of the founders of polytrauma treatment in USSR and Russia. For a long time he had been heading polytrauma department at the N.V. Sklifosovsky Research Institute for Emergency Medicine. Due to his work, algorithms of life sustaining and recovery of serious patients were developed. Professor V.A. Sokolov is the author of 6 monographies and about 300 periodical papers. Besides, he is the holder of 32 patents. Some of his inventions were popularized and manufactured. He had been leading active scientific work, which resulted in 6 doctoral dissertations and 15 candidate theses. The staff of N.V. Sklifosovsky Research Institute for Emergency Medicine congratulates on the anniversary.

  10. Professional Ethics Training and the Graduate Professors in the National Autonomous University of Mexico

    Directory of Open Access Journals (Sweden)

    Ana Hirsch Adler

    2010-08-01

    Full Text Available The purpose of the article is to present the results obtained with a sample of 704 professors of the forty graduate programs in UNAM, with the open question: Do you consider that a subject about professional ethics should be included for all students?, with which contents? This question is part of an instrument applied in 2006 and 2007. The majority expressed that it should exist a special subject about professional ethics. All the answers were codified in four categories. We introduced two other sources of information: the answers to the same question asked in 2004 to 11 professors from different universities in Spain, and three training proposals given by the professors interviewed.

  11. O uso das TIC no trabalho de professores universitários de língua inglesa The ICT use in the work of English language professors

    Directory of Open Access Journals (Sweden)

    Glenda Cristina Valim de Melo

    2012-01-01

    Full Text Available Este artigo apresenta as representações sobre o tipo de trabalho que docentes universitários de Língua Inglesa consideram realizar com as Tecnologias de Informação e Comunicação (TIC em sala de aula. Os aportes teórico-metodológicos estão embasados no Interacionismo Sociodiscursivo de Bronckart (2007; 2008, nas concepções de trabalho desenvolvidas pela Clínica da Atividade e Ergonomia e nas características de trabalho de Machado (2010. Participaram do estudo seis docentes universitários de Língua Inglesa que utilizam as TIC no trabalho. Os dados foram gerados via internet, via e-mails e Moodle. Cada participante produziu um texto em que relatou os usos que faria dessas ferramentas. Os resultados indicam que os docentes fazem usos semelhantes das ferramentas e que há impedimentos no uso das TIC para os docentes da universidade pública.This article presents representations about the kind of work that university professors hope to achieve when using Information & Communications Technology (ICT in the classroom. The theoretical background is based on Socio-discursive Interactionism, theories about work as developed in Clinical Activity and Ergonomics and in the characteristics of work proposed by Machado (2010. Six English language professors that use ICT at work participated in the research project. Data were collected via internet, through e-mail or Moodle. Each participant provided a text on their experiences and the use of ICT. The results indicate that university professors use the ICT in the same way, butsome restrictions to this matter are appointed by public university professors.

  12. Narratividade do professor: mediação e linguagem na sala de aula

    Directory of Open Access Journals (Sweden)

    Isabel Maganin Chesini

    2013-10-01

    Full Text Available OBJETIVO: construir e analisar uma experiência de formação do professor em sua narratividade e os efeitos da mesma na narratividade das crianças. MÉTODO: a amostra se constituiu de duas professoras de pré-escola, 28 alunos, 14 de cada professora sendo, um grupo experimental e o outro grupo controle, e os pais das crianças como controle ambiental. As avaliações foram feitas a partir de sessões de filmagem das professoras, coleta das narrativas das crianças e questionário sobre como desenvolviam a atividade de contar em casa. RESULTADOS: o processo de mediação fonoaudiólogo/professor, com enfoque na narrativa, provocou mudança no modo de narrar não só do professor, mas também nas categorias narrativas das crianças, demonstrando a importância de o profissional que assessore o professor em sua prática trazendo novos subsídios teóricos. CONCLUSÃO: após a realização desta pesquisa observou-se que a Experiência de Aprendizagem Mediada (EAM e os princípios interacionistas sobre a aquisição da linguagem e o desenvolvimento narrativo foram efetivos na construção de uma experiência formativa do professor para melhorar sua narratividade e que a evolução do professor se refletiu na evolução das habilidades narrativas das crianças.

  13. A case study of a college physics professor's pedagogical content knowledge

    Science.gov (United States)

    Counts, Margaret Cross

    Problem. Research into pedagogical content knowledge (PCK) has focused mainly on subject (content) matter, levels of expertise, or subject specific areas. Throughout the literature, Fernandez-Balboa & Stiehl (1992), Grossman (1988), Lenze (1994), Shulman (1986b), few studies about college professors appear. The rationale for this heuristic case study of PCK was to contribute to that body of knowledge as it applies to college teaching. The purpose of this study was twofold: first, to contribute to a broader conceptualization and understanding of the development of "general" PCK in college level teaching by generalizing Shulman's (1987) and Grossman's (1988) model of PCK to college professors; secondly, to describe how this professor's PCK was constructed. Method. The heuristic case study employed techniques of multiple semistructured participant interviews and supportive data sources. Analyses of the data was by analytical induction. Results. In this heuristic study five major themes emerged that reflected this professor's PCK: (a) knowledge of the purposes for teaching, (b) knowledge of students as learners, (c) knowledge of human communication: teaching as an interaction, (d) knowledge of curriculum and course design, and (e) knowledge of a positive learning environment. Six categories emerged that described the development of his PCK: (a) the need for content knowledge, (b) the need for communication, (c) sensitivity to the students' in-class behavior and environment, (d) personal reflection regarding the classroom environment, both before and after class, (e) teaching experience, and (f) collegial discussions about teaching. The construction of his PCK was attributed to the integration of subject matter knowledge, apprenticeship of observation, and classroom experience. Conclusions. Analyses revealed that this college professor's PCK was in a large part congruent with Shulman's (1986b) conceptualization and Grossman's (1988) four components of PCK. An additional

  14. [Professor J.Hall's merit on the development of Prague Medical Faculty].

    Science.gov (United States)

    Hlaváčková, Ludmila

    2015-01-01

    Hall was a remarkable personality among professors in Prague Medical Faculty. He was an extremely capable organizer and founder of the successful institutions that made Prague Medical Faculty famous. In 1844 he founded the University Journal, in 1845 he initiated the establishment of a laboratory for chemical and clinical examination in the general hospital, in 1847 he opened the University outpatient clinic, the first in the Austrian monarchy. He was an excellent teacher; however, his publications activity was small. Professor Hall belongs to the principal representatives of the so-called Prague Medical School.

  15. Pedagogical changes in an astronomy course for non-physics majors: Student and professor perspectives

    Science.gov (United States)

    MacLeod, Katarin; Razul, Mohamed Shajahan Gulam; Powell, Jamie

    2015-12-01

    Pedagogical changes were made in the delivery of a three-credit, first-year astronomy course offered to non-physics majors by a department of physics at a small undergraduate university in Canada. The professor of the course initiated this change to better meet the needs of the students enrolled. A brief description of some of the activities and teaching strategies is given, along with student and professor perceptions. Results indicate that it is possible to develop and deliver a rigorous, conceptually based astronomy course and that the effort is worth the result.

  16. AS REPRESENTAÇÕES SOCIAIS DE MORAL DE PROFESSORES DO ENSINO FUNDAMENTAL

    OpenAIRE

    Alessandra de Morais Shimizu

    2009-01-01

    Procurou-se, através desta pesquisa, inicialmente identificar as representações sociais de moral de professores do ensino fundamental da rede oficial. Buscou-se verificar se as representações encontradas baseavam-se em teorias psicológicas, conteúdos científicos supostamente abordados nos cursos de Habilitação Específica de 2° grau para o Magistério e, em especial, no curso superior de Pedagogia. Entrevistando quarenta professores, verificou-se que suas representações estavam sustentadas mais...

  17. Three Decades Investigating Humor and Laughter: An Interview With Professor Rod Martin

    OpenAIRE

    Rod Martin; Kuiper, Nicholas A.

    2016-01-01

    Since the start of the 21st century, the investigation of various psychological aspects of humor and laughter has become an increasingly prominent topic of research. This growth can be attributed, in no small part, to the pioneering and creative work on humor and laughter conducted by Professor Rod Martin. Dr. Martin’s research interests in humor and laughter began in the early 1980s and continued throughout his 32 year long career as a professor of clinical psychology at the University of We...

  18. Professor håber på åbenhed om CRISPR/Cas9

    DEFF Research Database (Denmark)

    Hokland, Peter

    2016-01-01

    CRISPR/Cas9 er navnet på en ny, revolutionerende genteknologi, der på sigt kan ændre menneskeheden. Forhåbentligt vil processen være være løbende opdateringer om frem- og tilbageskridt om teknikken, skriver professor.......CRISPR/Cas9 er navnet på en ny, revolutionerende genteknologi, der på sigt kan ændre menneskeheden. Forhåbentligt vil processen være være løbende opdateringer om frem- og tilbageskridt om teknikken, skriver professor....

  19. In memory of the professor Rachel Joffily Abath: Origins, academic life, longing and images

    Directory of Open Access Journals (Sweden)

    Luciana Ferreira da Costa

    2012-04-01

    Full Text Available Given the life trajectory of Professor Rachel Joffily Abath, this text recalls, as synthesis memorial five years after her death, her story and, in particular, her legacy to the Library and Information Science in Brazil. Four perspectives are presented in this paper: the origins and composition of the family of Professor Rachel; the story of her professional academic life, with greater contribution to teaching and research universities - specifically The Federal University of Paraíba and The University Center of João Pessoa -; a statement of the importance and longing; and memories through photographs.

  20. Response to Professor Stephen Jenkins’ comments on the World Income Inequality Database (WIID)

    DEFF Research Database (Denmark)

    Badgaiyan, Nina; Pirttilä, Jukka; Tarp, Finn

    2015-01-01

    Professor Stephen Jenkins (this issue) has conducted an extremely careful and insightful analysis of two datasets, WIID and SWIID. In this short response, we focus on his review of the WIID, maintained and published by UNU-WIDER in agreement with the World Bank. We wish to highlight at the outset...... that we are very grateful for Professor Jenkins’ expert advice and suggestions; and note that the WIID has over the past couple of years been developed in the direction recommended in the appraisal. This response provides, first, some background to the development and basic philosophy of the WIID...

  1. A fala em inglês - LE em aula: opiniões de alunos e professores

    OpenAIRE

    Arnaldo Menezes Junior

    2009-01-01

    O objetivo deste trabalho é analisar a problemática da fala do aluno em aula de Inglês como Língua Estrangeira, por meio das opiniões de alunos e professores. O principal aspecto analisado foi o processo motivacional dos alunos para falar inglês em aula. As respostas foram divididas em oito categorias: o professor, as atividades, os outros alunos, o material didático, a própria personalidade do aluno, a avaliação, o ambiente de aula, a falta de conhecimento da língua estrangeira e outros fato...

  2. Biographical Dictionary of the First Generation of Professors at the Hebrew University of Jerusalem

    OpenAIRE

    Eva Telkes

    2008-01-01

    Based on the model of studies carried out at the Institut d'histoire moderne et contemporaine on the elites in France, and more specifically on the model of the biographical dictionaries of the professors of the Sorbonne and the Collège de France, we aim at making a biographical dictionary of the professors of the Hebrew University of Jerusalem in its first period (1925-1948). This research complements the works of Israeli researchers who, since the seminar organized by Michael Heyd, Israel B...

  3. Adolescência e moralidade : o professor que faz a diferença

    OpenAIRE

    Andréa Bonetti Gallego

    2006-01-01

    Este estudo pesquisou como um professor pode ocupar o lugar de adulto significativo/respeitado e ser relevante no processo de constituição da moral do adolescente, através das representações dos alunos. O principal referencial teórico utilizado foi a Epistemologia Genética, em especial o desenvolvimento moral na obra de Jean Piaget. O tema norteador desta pesquisa é a questão do respeito nas relações entre professor e aluno, considerada a partir do lugar de adulto significativo que o professo...

  4. Um novo olhar sobre os cursos de formação de professores

    OpenAIRE

    Zimmermann, Erika; Bertani, Januária Araújo

    2003-01-01

    Este artigo tem o objetivo de debater e refletir sobre os Cursos de Formação dos Professores de Ciências e Matemática. Tais cursos apresentam antigos problemas, dentre eles, a desarticulação entre as disciplinas, a teoria e a prática, que refletem na construção do perfil do futuro professor. Assim, faz-se necessária uma nova forma de pensar e estruturar os Cursos de Formação Docente. Nesta perspectiva, este artigo apresenta alguns conceitos de Bachelard e Lakatos que podem contribuir para uma...

  5. “Emotions, Media and Political Campaign” by Professor Ann Crigler

    OpenAIRE

    Ricaud, Raphaël; Lechaux, Bleuwenn

    2012-01-01

    Ann Crigler, Professor of Political Science and Chair at the University of Southern California’s Dornsife College of Letters, Arts and Sciences, came to Paris VIII’s LabTop final 2010/2011 seminar on June 27, 2011, for a lecture entitled “Emotions, Media and Political Campaign”. She started out by insisting that the sum of the data and original findings she was presenting us with was a collaborative piece. Professor Crigler, two of her colleagues (Matthew Baum, from Harvard University and Mar...

  6. Representações sociais de professores sobre o autismo infantil

    OpenAIRE

    Michele Araújo Santos; Maria de Fátima de Souza Santos

    2012-01-01

    Este trabalho teve o objetivo de investigar, a partir da teoria das representações sociais, as ideias de senso comum que circulam entre professores acerca do autismo infantil. Buscamos compreender a lógica interna de tais teorias populares, mapear os saberes que as apoiam e as imagens que as concretizam. Os 16 participantes do estudo compuseram dois grupos: 9 professoras experientes na educação de crianças autistas e 7 professores sem experiência com tais crianças. Os dados obtidos através de...

  7. Further Characterization of 394-GHz Gyrotron FU CW GII with Additional PID Control System for 600-MHz DNP-SSNMR Spectroscopy

    Science.gov (United States)

    Ueda, Keisuke; Matsuki, Yoh; Fujiwara, Toshimichi; Tatematsu, Yoshinori; Ogawa, Isamu; Idehara, Toshitaka

    2016-09-01

    A 394-GHz gyrotron, FU CW GII, has been designed at the University of Fukui, Japan, for dynamic nuclear polarization (DNP)-enhanced solid-state nuclear magnetic resonance (SSNMR) experiments at 600-MHz 1H resonant frequency. After installation at the Institute for Protein Research (IPR), Osaka University, Japan, a PID feedback control system was equipped to regulate the electron gun heater current for stabilization of the electron beam current, which ultimately achieved stabilization of output power when operating in continuous wave (CW) mode. During exploration to further optimize operating conditions, a continuous tuning bandwidth of approximately 1 GHz was observed by varying the operating voltage at a fixed magnetic field. In the frequency range required for positive DNP enhancement, the output power was improved by increasing the magnetic field and the operating voltage from their initial operational settings. In addition, fine tuning of output frequency by varying the cavity cooling water temperature was demonstrated. These operating conditions and ancillary enhancements are expected to contribute to further enhancement of SSNMR signal.

  8. Dai-Huang-Fu-Zi-Tang Alleviates Intestinal Injury Associated with Severe Acute Pancreatitis by Regulating Mitochondrial Permeability Transition Pore of Intestinal Mucosa Epithelial Cells

    Directory of Open Access Journals (Sweden)

    Xin Kang

    2017-01-01

    Full Text Available Objective. The aim of the present study was to examine whether Dai-Huang-Fu-Zi-Tang (DHFZT could regulate mitochondrial permeability transition pore (MPTP of intestinal mucosa epithelial cells for alleviating intestinal injury associated with severe acute pancreatitis (SAP. Methods. A total of 72 Sprague-Dawley rats were randomly divided into 3 groups (sham group, SAP group, and DHFZT group, n=24 per group. The rats in each group were divided into 4 subgroups (n=6 per subgroup accordingly at 1, 3, 6, and 12 h after the operation. The contents of serum amylase, D-lactic acid, diamine oxidase activity, and degree of MPTP were measured by dry chemical method and enzyme-linked immunosorbent assay. The change of mitochondria of intestinal epithelial cells was observed by transmission electron microscopy. Results. The present study showed that DHFZT inhibited the openness of MPTP at 3, 6, and 12 h after the operation. Meanwhile, it reduced the contents of serum D-lactic acid and activity of diamine oxidase activity and also drastically relieved histopathological manifestations and epithelial cells injury of intestine. Conclusion. DHFZT alleviates intestinal injury associated SAP via reducing the openness of MPTP. In addition, DHFZT could also decrease the content of serum diamine oxidase activity and D-lactic acid after SAP.

  9. Impact of Martial Arts (Judo, Karate, and Kung Fu) on Bone Mineral Density Gains in Adolescents of Both Genders: 9-Month Follow-Up.

    Science.gov (United States)

    Ito, Igor H; Kemper, Han C G; Agostinete, Ricardo R; Lynch, Kyle R; Christofaro, Diego G D; Ronque, Enio R; Fernandes, Rômulo A

    2017-11-01

    To compare bone mineral density (BMD) gains in adolescents of both genders stratified according to different martial art styles in a 9-month follow-up study. The longitudinal study consisted of 29 adolescents of both genders and age between 11 and 17 years stratified into a control group (not engaged in any sport) and 50 fighters (kung fu/karate, n = 29; judo, n = 21). All 79 subjects underwent anthropometric measures (weight, height, leg length, and height set) and dual-energy X-ray absorptiometry (BMD, in g/cm 2 ) at 2 moments, baseline and 9 months later. Maturity offset (age at peak height velocity), lean soft tissue, chronological age, and resistance training were treated as covariates. Male judoists presented higher gains in BMD-spine [0.098 g/cm 2 (95% confidence interval, 0.068-0.128)] than control group [0.040 g/cm 2 (95% confidence interval, 0.011-0.069)] (post hoc test with P = .030). There was no effect of martial art on BMD gains among girls. Independently of gender, in all multivariate models, lean soft tissue constituted the most relevant covariate. Judo practice in adolescents affected the bone accrual significantly after 9-month follow-up compared with controls, mainly in boys.

  10. iTRAQ-Based Proteomics of Chronic Renal Failure Rats after FuShengong Decoction Treatment Reveals Haptoglobin and Alpha-1-Antitrypsin as Potential Biomarkers

    Directory of Open Access Journals (Sweden)

    Yu Yang

    2017-01-01

    Full Text Available Background. Chronic renal failure (CRF has become a global health problem and bears a huge economic burden. FuShengong Decoction (FSGD as traditional Chinese medicine has multiple pharmacological effects. Objectives. To understand the underlying molecular mechanism and signaling pathway involved in the FSGD treatment of CRF and screen differentially expressed proteins in rats with CRF treated with FSGD. Methods. Thirty-three male Sprague-Dawley rats were randomly divided into control group, CRF group, and FSGD group. Differentially expressed proteins were screened by iTRAQ coupled with nanoLC-MS/MS, and these identified proteins were later analyzed by GO, KEGG, and STRING. Additionally, haptoglobin (HP and alpha-1-antitrypsin (AAT were finally verified by ELISA, Western blot, and real time PCR. Results. A total of 417 proteins were identified. Nineteen differentially expressed proteins were identified in the FSGD group compared with the model group, of which 3 proteins were upregulated and 16 proteins were downregulated. Cluster analysis indicated that inflammatory response was associated with these proteins and complement and coagulation cascade pathways were predominantly involved. The validation methods further confirmed that the levels of HP and AAT were significantly increased. Conclusions. HP and AAT may be the important biomarkers in the pathogenesis of CRF and FSGD therapy.

  11. Role of GSTM1 Copy Number Variant in the Prognosis of Thai Colorectal Cancer Patients Treated with 5-FU-based Chemotherapy

    Science.gov (United States)

    Pongtheerat, Tanett; Saelee, Pensri

    2016-10-01

    Background: Glutathione S-transferase M1 (GSTM1) is involved in the detoxification of carcinogenic agents. DNA copy number variants of GSTM1 may be associated with cancer progression and may result in reduced survival time of various cancers. Determination of DNA copy number variants was here used to assess the association between GSTM1 copy number variant and pathological status and survival time of colorectal-cancer patients treated with 5-fluorouracil-based chemotherapy. Methods: One hundred thirteen Thai colorectal-cancer patients were investigated for GSTM1 copy number variant by real-time PCR. Relationships between gene copy number variants and clinico-pathological parameters were determined. Result: Associations were evident between GSTM1 copy number and stage of tumor (P = 0.026) and metastasis at diagnosis (P = 0.049), with odds ratio values of 0.2 and 0.3 respectively. Conclusions: GSTM1 copy number variant was here not related with reduced overall survival for the colorectal-cancer patients receiving 5-FU-based chemotherapy. Creative Commons Attribution License

  12. The ReFuGe 2020 consortium - Using ‘omics’ approaches to explore the adaptability and resilience of coral holobionts to environmental change

    Directory of Open Access Journals (Sweden)

    Christian Robert Voolstra

    2015-09-01

    Full Text Available Human-induced environmental changes have been linked directly with loss of biodiversity. Coral reefs, which have been severely impacted by anthropogenic activities over the last few decades, exemplify this global problem and provide an opportunity to develop research addressing key knowledge gaps through ‘omics’-based approaches. While many stressors, e.g. global warming, ocean acidification, overfishing and coastal development have been identified, there is an urgent need to understand how corals function at a basic level in order to conceive strategies for mitigating future reef loss. In this regard, availability of fully sequenced genomes has been immensely valuable in providing answers to questions of organismal biology. Given that corals are metaorganisms comprised of the coral animal host, its intracellular photosynthetic algae, and associated microbiota (i.e. bacteria, archaea, fungi, viruses, these efforts must focus on entire coral holobionts. The Reef Future Genomics 2020 (ReFuGe 2020 consortium has formed to sequence hologenomes of ten coral species representing different physiological or functional groups to provide foundation data for coral reef adaptation research that is freely available to the research community.

  13. Effects of Chinese medicine shen-fu injection on the expression of inflammatory cytokines and complements during post-resuscitation immune dysfunction in a porcine model.

    Science.gov (United States)

    Zhang, Qian; Li, Chun-sheng; Wang, Shuo; Gu, Wei

    2016-02-01

    To investigate the action of Shen-Fu Injection (SFI) in regulating the expression of the serum complements and inflammatory cytokines synthesized and released in response to the stress of global ischemia accompanying cardiac arrest (CA) and resuscitation. Thirty pigs were randomly divided into the sham (n=6) and 3 returns of spontaneous circulation (ROSC) groups (n=24). After 8-min untreated ventricular fibrillation and 2-min basic life support, 24 pigs of the ROSC groups were randomized into three groups (n=8 per group), which received central venous injection of SFI (SFI group), epinephrine (EP group), or saline (SA group). Hemodynamic status and blood samples were obtained at 0, 0.5, 1, 2, 4, 6, 12, and 24 h after ROSC. Serum concentrations of specific activation markers of the complement system C3, C4 and C5b-9 were increased during cardiopulmonary resuscitation through 24 h after ROSC. There were intense changes of various pro-inflammatory cytokines and anti-inflammatory cytokines as early as 0.5 h after CA. Compared with the EP and SA groups, SFI treatment reduced the proinflammatory cytokines levels of interleukin (IL)-6, IL-8 and tumor necrosis factor α (TNF-α, Pcytokine levels of IL-4 and IL-10 (Pcytokines levels. The current study provided an experimental basis for the clinical application of a potential pharmacologic target for post resuscitation immune dysfunction.

  14. Silencing of NRF2 Reduces the Expression of ALDH1A1 and ALDH3A1 and Sensitizes to 5-FU in Pancreatic Cancer Cells

    Directory of Open Access Journals (Sweden)

    Hong-Quan Duong

    2017-07-01

    Full Text Available Pancreatic cancer remains an intractable cancer with a poor five-year survival rate, which requires new therapeutic modalities based on the biology of pancreatic oncogenesis. Nuclear factor E2 related factor-2 (NRF2, a key cytoprotective nuclear transcription factor, regulates antioxidant production, reduction, detoxification and drug efflux proteins. It also plays an essential role in cell homeostasis, cell proliferation and resistance to chemotherapy. We aimed to evaluate the possibility that modulation of NRF2 expression could be effective in the treatment of pancreatic cancer cells. We investigated whether the depletion of NRF2 by using small interfering RNAs (siRNAs is effective in the expression of biomarkers of pancreatic cancer stemness such as aldehyde dehydrogenase 1 family, member A1 (ALDH1A1 and aldehyde dehydrogenase 3 family, member A1 (ALDH3A1. NRF2 knockdown markedly reduced the expression of NRF2 and glutamate-cysteine ligase catalytic subunit (GCLC in cell lines established from pancreatic cancers. NRF2 silencing also decreased the ALDH1A1 and ALDH3A1 expression. Furthermore, this NRF2 depletion enhanced the antiproliferative effects of the chemotherapeutic agent, 5-fluorouracil (5-FU in pancreatic cancer cells.

  15. Antidiabetic Effect of Tibetan Medicine Tang-Kang-Fu-San on High-Fat Diet and Streptozotocin-Induced Type 2 Diabetic Rats

    Directory of Open Access Journals (Sweden)

    Bailu Duan

    2017-01-01

    Full Text Available The aim of this study was to investigate the antidiabetic effects of a Tibetan medicine, Tang-Kang-Fu-San (TKFS, on experimental type 2 diabetes mellitus (T2DM rats and to explore its underlying mechanisms. Firstly two major chemical compositions of TKFS, gallic acid and curcumin, were characterized by HPLC fingerprint analysis. Next T2DM in rats was induced by high-fat diet and a low-dose streptozotocin (STZ 35 mg/kg. Then oral gavage administration of three different doses of TKFS (0.3 g/kg, 0.6 g/kg, and 1.2 g/kg was given to T2DM rats. Experimental results showed that TKFS dramatically reduced the levels of fasting blood glucose, fasting blood insulin, triglyceride, total cholesterol, LDL cholesterol, and HDL cholesterol, even though it did not alter the animal body weight. The downregulation of phosphorylation-AKT (p-AKT and glucose transporter-4 (GLUT4 in skeletal muscle of T2DM rats was restored and abnormal pathological changes in pancreas tissues were also improved. Our work showed that TKFS could alleviate diabetic syndromes, maintain the glucose homeostasis, and protect against insulin resistance in T2DM rats, and the improvement of AKT phosphorylation and GLUT4 translocation in skeletal muscle would be one of its possible underlying mechanisms.

  16. On-line monitoring the extract process of Fu-fang Shuanghua oral solution using near infrared spectroscopy and different PLS algorithms

    Science.gov (United States)

    Kang, Qian; Ru, Qingguo; Liu, Yan; Xu, Lingyan; Liu, Jia; Wang, Yifei; Zhang, Yewen; Li, Hui; Zhang, Qing; Wu, Qing

    2016-01-01

    An on-line near infrared (NIR) spectroscopy monitoring method with an appropriate multivariate calibration method was developed for the extraction process of Fu-fang Shuanghua oral solution (FSOS). On-line NIR spectra were collected through two fiber optic probes, which were designed to transmit NIR radiation by a 2 mm flange. Partial least squares (PLS), interval PLS (iPLS) and synergy interval PLS (siPLS) algorithms were used comparatively for building the calibration regression models. During the extraction process, the feasibility of NIR spectroscopy was employed to determine the concentrations of chlorogenic acid (CA) content, total phenolic acids contents (TPC), total flavonoids contents (TFC) and soluble solid contents (SSC). High performance liquid chromatography (HPLC), ultraviolet spectrophotometric method (UV) and loss on drying methods were employed as reference methods. Experiment results showed that the performance of siPLS model is the best compared with PLS and iPLS. The calibration models for AC, TPC, TFC and SSC had high values of determination coefficients of (R2) (0.9948, 0.9992, 0.9950 and 0.9832) and low root mean square error of cross validation (RMSECV) (0.0113, 0.0341, 0.1787 and 1.2158), which indicate a good correlation between reference values and NIR predicted values. The overall results show that the on line detection method could be feasible in real application and would be of great value for monitoring the mixed decoction process of FSOS and other Chinese patent medicines.

  17. YiQiFuMai Powder Injection Protects against Ischemic Stroke via Inhibiting Neuronal Apoptosis and PKCδ/Drp1-Mediated Excessive Mitochondrial Fission

    Directory of Open Access Journals (Sweden)

    Yingqiong Xu

    2017-01-01

    Full Text Available YiQiFuMai (YQFM powder injection has been reported to be used in cardiovascular and nervous system diseases with marked efficacy. However, as a treatment against diseases characterized by hypoxia, lassitude, and asthenia, the effects and underlying mechanisms of YQFM in neuronal mitochondrial function and dynamics have not been fully elucidated. Here, we demonstrated that YQFM inhibited mitochondrial apoptosis and activation of dynamin-related protein 1 (Drp1 in cerebral ischemia-injured rats, producing a significant improvement in cerebral infarction and neurological score. YQFM also attenuated oxidative stress-induced mitochondrial dysfunction and apoptosis through increasing ATP level and mitochondria membrane potential (Δψm, inhibiting ROS production, and regulating Bcl-2 family protein levels in primary cultured neurons. Moreover, YQFM inhibited excessive mitochondrial fission, Drp1 phosphorylation, and translocation from cytoplasm to mitochondria induced by oxidative stress. We provided the first evidence that YQFM inhibited the activation, association, and translocation of PKCδ and Drp1 upon oxidative stress. Taken together, we demonstrate that YQFM ameliorates ischemic stroke-induced neuronal apoptosis through inhibiting mitochondrial dysfunction and PKCδ/Drp1-mediated excessive mitochondrial fission. These findings not only put new insights into the unique neuroprotective properties of YQFM associated with the regulation of mitochondrial function but also expand our understanding of the underlying mechanisms of ischemic stroke.

  18. Professor Darleane C. Hoffman, Senior Advisor & Charter Director Seaborg Institute for Transactinium Science Livermore, California and Dr Marvin Hoffman accompanied by Professor Heinz Gäggeler, University of Bern and Paul Scherrer Institut Villigen.

    CERN Multimedia

    Maximilien Brice

    2001-01-01

    Photo 02 : Visit of Professor Darleane C. Hoffman, Senior Advisor & Charter Director, Seaborg Institute for Transactinium Science, Livermore, California with (from left to right) Dr Mats Lindroos, ISOLDE Technical Coordinator; Professor Heinz Gäggeler, University of Bern and Paul Scherrer Institute Villigen, and Dr Marvin Hoffman.

  19. Professors of Reading Educations' Perceptions and Practices Surrounding the Issues of Teaching Reading and Learning through Digital Media

    Science.gov (United States)

    Crumpley-Fisk, Janine S.

    2012-01-01

    The purpose of this study was to examine the practices and perceptions of professors of reading education in the issues surrounding teaching reading and learning with digital media. This study aimed to understand the strategies and thoughts of a select group of professors of reading education as they worked with pre-service teachers in preparing…

  20. Strategies Used by Professors through Virtual Educational Platforms in Face-to-Face Classes: A View from the Chamilo Platform

    Science.gov (United States)

    Valencia, Heriberto Gonzalez; Villota Enriquez, Jackeline Amparo; Agredo, Patricia Medina

    2017-01-01

    This study consisted in characterizing the strategies used by professors; implemented through virtual educational platforms. The context of this research were the classrooms of the Santiago de Cali University and the virtual space of the Chamilo virtual platform, where two professors from the Faculty of Education of the same university…

  1. Paying Attention to Students' Experiences of Learning: A Study of Liberal Arts College Professors and Their Learning about Teaching

    Science.gov (United States)

    Phifer, Tamsyn Rene

    2010-01-01

    This research examines private liberal arts college professors' learning about teaching, in particular, how they come to pay attention to their students' experiences of learning. This study relies on interview, observation, and document analysis to consider the experiences of 16 professors whose teaching changed as they carried out their work. All…

  2. Gender and Cross-Cultural Perceptions of Professors' Behaviors: A Comparison of Chinese and American College Students

    Science.gov (United States)

    Stork, Elizabeth; Hartley, Nell T.

    2014-01-01

    A gender and nationality comparison study of Chinese students in China and American students in the U.S. (N = 405) was conducted to explore perceptions about potentially offensive behaviors of professors in the college classroom using the Student Perceptions of Professors' Classroom Behaviors (SPPCB). Within-country and between-country comparisons…

  3. Private Liberal Arts College Professors' Deepened Engagements with Students beyond the Classroom: An Exploratory Study

    Science.gov (United States)

    Pereira, Kimberley Boulanger

    2012-01-01

    This study uses semi-structured interviews to examine how 33 professors, working at two private liberal arts colleges and identified by their local faculty colleagues as professors who deeply engage with students beyond the classroom, experience such engagements and incorporate them into their work lives. The study defines "deepened…

  4. Professor om brexit-åbning: Det bliver sværere i næste fase

    DEFF Research Database (Denmark)

    Wind, Marlene

    2017-01-01

    Professor og centerleder, Marlene Wind, var den 8. december i Vejle Amts Folkeblad, hvor hun kommenterede på udviklingen i Brexit-forhandlingerne i forlængelse af udmeldingen om, at forhandlingerne er klar til den næste fase. Professor Wind kalder dette for et gennembrud, men pointerer også at de...

  5. Mapping the Power of Law Professors: The Role of Scientific and Social Capital

    Science.gov (United States)

    Bühlmann, Felix; Benz, Pierre; Mach, André; Rossier, Thierry

    2017-01-01

    As a scientific discipline and profession, law has been for centuries at the heart of social and political power of many Western societies. Professors of law, as influential representatives of the profession, are important powerbrokers between academia, politics and the corporate world. Their influence is based on scientific reputation,…

  6. Assistant professor's National Science Foundation CAREER grant will help understand cell cycle model

    OpenAIRE

    Mackay, Steven D.

    2010-01-01

    Yang Cao, an assistant professor in the computer science department at Virginia Tech's College of Engineering, has won a $550,000 National Science Foundation Faculty Early Career Development (CAREER) award to develop computer simulation methods that will better understand the complex, discrete, and stochastic cell cycle model.

  7. The Miner's Canary: A Critical Race Perspective on the Representation of Black Women Full Professors

    Science.gov (United States)

    Croom, Natasha; Patton, Lori

    2012-01-01

    This article examines experiences of a Black woman full professor, and the benefits and privileges associated with reaching this rank. Its purpose is to leave little room for conjecture about the rank and those who have earned it. Using critical race theory and a critical race feminism framework coupled with the concept of the miner's canary, we…

  8. Professor Claudine Blanchet-Bardon: French dermatologist and leading authority on inherited ichthyoses ?

    OpenAIRE

    Daunton, A.; Shipman, A.R.

    2016-01-01

    This article recounts the early life and professional achievements through 2016 of Professor Claudine Blanchet-Bardon, a French dermatologist who is known for her work in dermatogenetics, genetic counseling, and the care of patients with ichthyoses among other important work.

  9. Aspectos motivacionais e afetivos na mediação de professores alfabetizadores

    Directory of Open Access Journals (Sweden)

    Azevedo, Cleomar

    2010-01-01

    Full Text Available Este artigo é o resultado de uma pesquisa que parte da seguinte questão: o que diferencia o professor que obtém sucesso no processo de alfabetização? Levanto a hipótese que na mediação os aspectos motivacionais e afetivos são componentes que se fazem presente na atuação desses professores alfabetizadores. O objetivo desta pesquisa foi o de levantar os aspectos motivacionais e afetivos na mediação do processo de alfabetização, através da fala de professores alfabetizadores. Foram entrevistados 18 professores com a premissa de serem bons alfabetizadores. Investigar o que mobiliza e caracteriza a ação dos docentes, que mesmo possuindo inúmeras variáveis que interfiram negativamente nesse processo, conseguem obter êxito no desenvolvimento da alfabetização de seus alunos é uma possibilidade de levantar questões voltadas à problemática da aprendizagem do processo de alfabetização

  10. To Touch or Not To Touch: An Examination of Tactile Communication between College Student and Professor.

    Science.gov (United States)

    Sanderson, Cami M.; Jorgensen, Jerry D.

    A study examined the perceptions of appropriateness regarding four types of touch between college students and professors. Subjects included 382 students, 108 men and 202 women, enrolled in a basic speech communication course at a large midwestern university. Using video depictions, an analysis of variance was conducted exploring differences in…

  11. Portfolio : Theory and Practice of the Pedagogical Methods Course for Assistant Professors at Aalborg University

    DEFF Research Database (Denmark)

    Hansen, Søren

    2002-01-01

    At Aalborg University staff development is organized as a pedagogical course that all Assistant Professors must attend. The pedagogical principles are that learning takes place in action and by keeping a reflective dialog up with supervisors, students and colleagues. Relevant theory is learned from...

  12. Math Professors Turn to Writing to Help Students Master Concepts of Calculus and Combinatorics.

    Science.gov (United States)

    Turner, Judith Axler

    1989-01-01

    A growing number of mathematics professors are asking their students to keep journals, write papers, and answer essay questions on tests, arguing that students learn mathematical concepts better by articulating them. This is part of a trend toward teaching mathematics for understanding rather than by rote. (MSE)

  13. The Present State of the Business Law Education of Accounting Students: The Business Law Professor's Perspective

    Science.gov (United States)

    Kocakulah, Mehmet C.; Austill, A. David; Long, Brett

    2009-01-01

    The article aims to provide Certified Public Accountant (CPA) candidates, accounting faculty, the American Institute of Certified Public Accountants (AICPA), and the state boards of accountancy with an insight into the business law professor's perspective concerning the legal education of accountants. This article first describes various factors,…

  14. More on the Nature of Scientific Thought: Responses to Professors Lederman and Ohlsson.

    Science.gov (United States)

    Suchting, W. A.

    1996-01-01

    Provides author comments in response to the papers of Professors Lederman and Ohlsson in "Science and Education," Vol. 4, No. 4, 1995. These papers were in response to the paper "On the Nature of Scientific Thought" ("Science and Education," Vol. 4, No. 1). Includes 19 references. (DDR)

  15. Latina Professor Revitalizing Historical Memory: Resistance Politics and Transformation within Teacher Education

    Science.gov (United States)

    Arce, Josephine

    2013-01-01

    This study focuses on how a Chicana/Latina professor contributed to the development of social consciousness with Spanish bilingual credential candidates in a Teacher Education Multiple Subject Credential Program, in California, USA. As a teacher educator, my goals were to look deeply at my teaching approach and to evaluate what the students and I…

  16. How Do Young Tenured Professors Benefit from a Mentor? Effects on Management, Motivation and Performance

    Science.gov (United States)

    van der Weijden, Inge; Belder, Rosalie; van Arensbergen, Pleun; van den Besselaar, Peter

    2015-01-01

    Do young tenured professors who receive mentorship differ from those without mentorship in terms of motivation, scholarly performance, and group management practice? We conducted a survey among research group leaders in the biomedical and health sciences in the Netherlands, to study the effects of mentorship. Our results show that mentorship…

  17. From the "Ivory Tower" to the "University of the Poor": A Professor's Educational Journey

    Science.gov (United States)

    Schoorman, Dilys

    2016-01-01

    Adopting a Freirean perspective, the purpose of this autoethnography is to reframe the typical relationship between university educators and communities in poverty by highlighting the educative impact of such a community on a university professor's academic, cross-cultural critical and civic learning. By reframing communities in poverty as sources…

  18. A Peace Education Pioneer: A Swedish Professor in Pedagogy Dedicated to Peace Education--Ake Bjerstedt

    Science.gov (United States)

    Andersson, Irene; Johansson, Roger

    2010-01-01

    This article profiles Swedish professor Ake Bjerstedt and discusses his contributions to the field of peace education. Bjerstedt helped history researchers a great deal by writing bibliographies like "Educating towards a culture of peace. A select bibliography focusing on the last 25 years", 2001, and by keeping a well organized archive…

  19. REPRESENTAÇÃO SOCIAL DO PROFESSOR SOBRE AS DIFICULDADE DE APRENDIZAGEM DO ALUNO

    Directory of Open Access Journals (Sweden)

    Joana Jesus Silva

    2016-11-01

    Full Text Available O presente trabalho analisa os processos e conteúdos representacionais dos professores de 9 instituições de ensino públicas rurais de um município do Vale do Paraíba Paulista com relação às dificuldades de aprendizagem do aluno. Para este fim, foram realizadas 15 entrevistas com professores do ensino fundamental. Uma análise de conteúdo informatizada de tais entrevistas com o software ALCESTE® revelou 7 classes de discursos, uma delas especificamente ligada ao tema “dificuldade de aprendizagem”. A representação social da dificuldade de aprendizagem para esse grupo de professores revela que os sujeitos atribuem ao próprio aluno e ao seu contexto sócio-econômico-cultural a responsabilidade pelo insucesso, conferindo aos fatores externos a principal causa destas dificuldades. Os professores culpabilizam especialmente as condições de vida do educando e a ausência da família na vida escolar do estudante. Foi possível ainda identificar os processos de objetivação e ancoragem que estão na gênese da representação social da dificuldade de aprendizagem do aluno.

  20. Teacher Trainers: an analysis of the strategies that make more successful professors from the students' viewpoint

    Directory of Open Access Journals (Sweden)

    Ana Luiza de Quadros

    2016-03-01

    Full Text Available Only in the last decades has the performance of teacher trainers who did graduate studies in specific areas of knowledge been object of investigation. With the main goal of analyzing strategies used by higher education professors who work in teacher training, we selected four Chemistry professors who are well accepted by the students, two who classified their own classes as more interactive and the other two, as less interactive. We video recorded a set of classes by each professor and submitted them first to a broad analysis and then to a microanalysis. We later shared the analysis results with the participants to be able to further investigate how they had constructed their strategies. We observed that they presented characteristics common in the broad analysis. The microanalysis revealed differentiated teaching strategies in the more interactive classes and in the less interactive classes. The strategies had been constructed based on the teaching models that the professors had had (less interactive or on their counter-model (more interactive.