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Sample records for prof tim brown

  1. Brown, Prof. Robert Hanbury

    Indian Academy of Sciences (India)

    Date of birth: 31 August 1916. Date of death: 16 January 2002. Last known address: White Cottage, Penton Mewsey, Near Andover, Hampshire SP11 ORQ, U.K.. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies ...

  2. Nadkarni, Prof. Mahendra Ganpatrao

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1989 Section: Mathematical Sciences. Nadkarni, Prof. Mahendra Ganpatrao Ph.D. (Brown), FNA. Date of birth: 17 January 1939. Specialization: Ergodic Theory and Commutative Harmonic Analysis Address: Emeritus Professor, Department of Mathematics, University of Bombay, Vidyanagari, Kalina, ...

  3. TIM CERN

    CERN Multimedia

    2016-01-01

    -What it is TIM, Train Inspection Monorail for the LHC -What is it used for Real time measurements and inspections along the LHC tunnel -How is it working Autonomous vehicle following pre-defined missions Embedded fail safe control and different measurement technologies Runs on battery with autonomous charging mechanism when stands still -Some interesting/curious information about it Adaptive speed up to 6 km/h Monitoring of tunnel structure, oxygen, communication bandwidth and temperature Equipped with a radioprotection probe for radiation mapping of the LHC Provides visual and infrared imaging of the LHC Compact design to be able to cross the LHC sector and ventilation doors Several different wagons can be integrated for specific missions 2 TIM units currently running in the LHC and parked waiting for commands in the CMS bypass

  4. KEPEMIMPINAN YANG MEMBANGUN TIM

    Directory of Open Access Journals (Sweden)

    Wahyu A Rini

    2006-05-01

    Full Text Available Kepemimpinan pada dasarnya tidak bisa berjalan sendirian. Kepemimpinan muncul karena kerja sama dengan orang lain. Tanpa orang lain, tidak ada pemimpin,  kepemimpinan bukanlah upaya satu orang saja, melainkan melibatkan kerja sama tim. Tim yang handal adalah tim yang bisa bekerja sama, saling percaya, dan saling menghargai. Dalam membangun tim kerja adalah mengupayakan  kesamaan visi, misi dan tujuan yang ingin dicapai dengan terus melakukan brainstorming agar kesepakatan bersama dapat tercapai. Tantangan utama yang berhubungan dengan aspek kepemimpinan Tim adalah membangun budaya yang kondusif serta menciptakan atmosfer yang mendukung kerja tim. Pemimpin tim yang percaya kepada teamwork biasanya memiliki posisi yang lebih baik untuk membangun kultur teamwork. Tim dengan kinerja tinggi pada umumnya heterogen. Artinya, tim yang mencapai tingkat kinerja yang tinggi tidak terdiri dari orang-orang yang benar-benar sama. Melainkan, tim ini terdiri dari para anggota yang mempunyai kecakapan-kecakapan yang saling melengkapi. Fondasi dari sebuah tim kerja yang sukses dengan mengedepankan hubungan antar manusia, tim kerja yang efektif adalah saling mempedulikan satu dengan lainnya, membangun disiplin serta membangun komitmen agar tim dapat bekerja secara efektif.

  5. Rama, Prof.

    Indian Academy of Sciences (India)

    Elected: 1969 Section: Earth & Planetary Sciences. Rama, Prof. Ph.D. (Mumbai), FNA, FNAAS. Date of birth: 16 March 1929. Specialization: Isotope Hydrology Address: Y-4, Sector 9, CBD, Navi Mumbai 400 614, Maharashtra Contact: Residence: (022) 2757 0081. Email: rama139@yahoo.co.in. YouTube; Twitter; Facebook ...

  6. TIM the Robot

    CERN Multimedia

    Noemi Caraban

    2016-01-01

    -What it is TIM, Train Inspection Monorail for the LHC -What is it used for Real time measurements and inspections along the LHC tunnel -How is it working Autonomous vehicle following pre-defined missions Embedded fail safe control and different measurement technologies Runs on battery with autonomous charging mechanism when stands still -Some interesting/curious information about it Adaptive speed up to 6 km/h Monitoring of tunnel structure, oxygen, communication bandwidth and temperature Equipped with a radioprotection probe for radiation mapping of the LHC Provides visual and infrared imaging of the LHC Compact design to be able to cross the LHC sector and ventilation doors Several different wagons can be integrated for specific missions 2 TIM units currently running in the LHC and parked waiting for commands in the CMS bypassThis video is about TIM_project OK

  7. Marks, Prof. Tobin J

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2011 Honorary. Marks, Prof. Tobin J. Date of birth: 25 November 1944. Address: Prof. of Materials Sci. & Engg., Department of Chemistry, Northwestern University, 2145, Sheridan Road, Evanston, IL 60208, USA Contact: Office: (+1-847) 491 5658. Email: t-marks@northwestern.edu. YouTube; Twitter ...

  8. Porsezian, Prof. Kuppuswamy

    Indian Academy of Sciences (India)

    Porsezian, Prof. Kuppuswamy Ph.D. (Bharathidasan), FNASc. Date of birth: 5 June 1963. Specialization: Nonlinear Solitons, Bose-Einstein Condensates, Solitons, Modulational Instability, Nonlinear Fibre Optics, Partial Differential Equations Address: Department of Physics, Pondicherry University, Kalapet, Puducherry 605 ...

  9. Joffe, Prof. Abram Fiodorovich

    Indian Academy of Sciences (India)

    Academy Public Lecture. Posted on 19 January 2018. Seasonal and Pandemic Influenza by Prof. Kanta Subbarao 25 January 2018 at 1600 hrs. Ground floor, Main auditorium, New Biological Sciences Building, IISc. Event Poster ...

  10. Mark, Prof. Herman Francis

    Indian Academy of Sciences (India)

    Academy Public Lecture. Posted on 19 January 2018. Seasonal and Pandemic Influenza by Prof. Kanta Subbarao 25 January 2018 at 1600 hrs. Ground floor, Main auditorium, New Biological Sciences Building, IISc. Event Poster ...

  11. Dale, Prof. Henry Hallett

    Indian Academy of Sciences (India)

    Academy Public Lecture. Posted on 19 January 2018. Seasonal and Pandemic Influenza by Prof. Kanta Subbarao 25 January 2018 at 1600 hrs. Ground floor, Main auditorium, New Biological Sciences Building, IISc. Event Poster ...

  12. Jagadish, Prof. Chennupati

    Indian Academy of Sciences (India)

    Academy Public Lecture. Posted on 19 January 2018. Seasonal and Pandemic Influenza by Prof. Kanta Subbarao 25 January 2018 at 1600 hrs. Ground floor, Main auditorium, New Biological Sciences Building, IISc. Event Poster ...

  13. Pauli, Prof. Wolfgang Armst

    Indian Academy of Sciences (India)

    Academy Public Lecture. Posted on 19 January 2018. Seasonal and Pandemic Influenza by Prof. Kanta Subbarao 25 January 2018 at 1600 hrs. Ground floor, Main auditorium, New Biological Sciences Building, IISc. Event Poster ...

  14. Hopkins, Prof. Frederick Gowland

    Indian Academy of Sciences (India)

    Academy Public Lecture. Posted on 19 January 2018. Seasonal and Pandemic Influenza by Prof. Kanta Subbarao 25 January 2018 at 1600 hrs. Ground floor, Main auditorium, New Biological Sciences Building, IISc. Event Poster ...

  15. Burma, Prof. Debi Prosad

    Indian Academy of Sciences (India)

    , Prof. Debi Prosad D.Phil. (Calcutta), FNA, FNASc, FAMS. Date of birth: 1 February 1925. Date of death: 4 February 2005. Specialization: Biochemistry and Molecular Biology Last known address: CF 186, Sector I, Salt Lake City, Kolkata 700 ...

  16. Bhatia, Prof. Suresh Kumar

    Indian Academy of Sciences (India)

    Bhatia, Prof. Suresh Kumar Ph.D. (Pennsylvania). Date of birth: 8 September 1952. Specialization: Transport & Reaction in Nanostructured Porous Media, Adsorption and Mathematical Modelling Address: Professor, Department of Chemical Engineering, University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia

  17. Athreya, Prof. Krishna Balasundaram

    Indian Academy of Sciences (India)

    Elected: 1974 Section: Mathematical Sciences. Athreya, Prof. Krishna Balasundaram Ph.D. (Stanford). Date of birth: 12 December 1939. Specialization: Probability Theory, Stochastic Processes and Mathematical Statistics Address: Distinguished Professor Emeritus, Departments of Mathematics & Statistics, Iowa State ...

  18. Inamdar, Prof. Maneesha Shreedhar

    Indian Academy of Sciences (India)

    Inamdar, Prof. Maneesha Shreedhar Ph.D. (Bombay). Date of birth: 25 February 1967. Specialization: Stem Cell Biology, Cardiovascular Development, Hematopoiesis & Angiogenesis Address: Molecular Biology & Genetics Unit, JN Centre for Advanced Scientific Research, Jakkur, Bengaluru 560 064, Karnataka Contact:

  19. Mallik, Prof. Ranjan Kumar

    Indian Academy of Sciences (India)

    Academy Public Lecture. Posted on 19 January 2018. Seasonal and Pandemic Influenza by Prof. Kanta Subbarao 25 January 2018 at 1600 hrs. Ground floor, Main auditorium, New Biological Sciences Building, IISc. Event Poster ...

  20. Vishveshwara, Prof. Saraswathi

    Indian Academy of Sciences (India)

    Academy Public Lecture. Posted on 19 January 2018. Seasonal and Pandemic Influenza by Prof. Kanta Subbarao 25 January 2018 at 1600 hrs. Ground floor, Main auditorium, New Biological Sciences Building, IISc. Event Poster ...

  1. Bhargava, Prof. Manjul

    Indian Academy of Sciences (India)

    ACADEMY PUBLIC LECTURE: How Things Break – The Mechanics of Dynamic Fracture. Posted on 16th February 2018. by Prof. Krishnaswamy Ravi-Chandar. in Faculty Hall, Indian Institute of Science. on 23 February 2018, 1500 event poster ...

  2. Surolia, Prof. Namita

    Indian Academy of Sciences (India)

    Academy Public Lecture. Posted on 19 January 2018. Seasonal and Pandemic Influenza by Prof. Kanta Subbarao 25 January 2018 at 1600 hrs. Ground floor, Main auditorium, New Biological Sciences Building, IISc. Event Poster ...

  3. Chaudhari, Prof. Raghunath Vitthal

    Indian Academy of Sciences (India)

    Elected: 1992 Section: Engineering & Technology. Chaudhari, Prof. Raghunath Vitthal Ph.D. (Mumbai), FNA, FNAE. Date of birth: 17 April 1948. Specialization: Homogeneous and Heterogeneous Catalysis, Biomass Conversion; Multiphase Reactors, Chemical Reaction Engineering and Kinetics & Mechanism Address: ...

  4. Sankara Rao, Prof. Kolluri

    Indian Academy of Sciences (India)

    Sankara Rao, Prof. Kolluri Ph.D. (Bangalore). Date of birth: 15 December 1939. Specialization: Plant Developmental Biology, Biotechnology, Biodiversity Informatics & Plant Systematics Address: Distinguished Fellow, Centre for Ecological Sciences, Indian Institute of Science, Bengaluru 560 012, Karnataka Contact:

  5. Sarin, Prof. Manmohan

    Indian Academy of Sciences (India)

    Elected: 2000 Section: Earth & Planetary Sciences. Sarin, Prof. Manmohan Ph.D. (Gujarat), FNA, FNASc. Date of birth: 26 July 1951. Specialization: Atmospheric & Aerosol Chemistry and Chemical Oceanography Address: INSA Senior Scientist, Physical Research laboratory, Navarangpura, Ahmedabad 380 009, Gujarat

  6. Venkatesh, Prof. Kareenhalli Viswanath

    Indian Academy of Sciences (India)

    Elected: 2016 Section: Engineering & Technology. Venkatesh, Prof. Kareenhalli Viswanath Ph.D. (Purdue). Date of birth: 7 June 1967. Specialization: Biosystems Engineering, Synthetic Biology, Metabolic Engineering Address: Department of Chemical Engineering, Indian Institute of Technology, Powai, Mumbai 400 076, ...

  7. Bhattacharya, Prof. Santanu

    Indian Academy of Sciences (India)

    Elected: 2000 Section: Chemistry. Bhattacharya, Prof. Santanu Ph.D. (Rutgers), FNA, FTWAS. Date of birth: 23 April 1958. Specialization: Chemical Biology, Molecular Theranostics, Soft Materials, Supramolecular Analytical Chemistry, Nanoscience & Nanotechnology Address: Director, Indian Association for the Cultivation ...

  8. Krishnamoorthy, Prof. Guruswamy

    Indian Academy of Sciences (India)

    Elected: 2000 Section: General Biology. Krishnamoorthy, Prof. Guruswamy Ph.D. (Bombay), FNA. Date of birth: 10 May 1950. Specialization: Biophysical Chemistry, Laser Spectroscopy and Macromolecular Dynamics Address: Honorary Professor, Department of Biotechnology, Anna University, Guindy, Chennai 600 025, ...

  9. Taal In Media : TIM 2013

    NARCIS (Netherlands)

    Reker, Siemon

    2013-01-01

    In deze rubriek worden beschouwinkjes op basis van uitingen in (of op) media geplaatst, geschreven door medewerkers van het Bureau Groninger Taal en Cultuur. Blijf via Twitter (@BGTCRuG) op de hoogte van het verschijnen van nieuwe TIM's.

  10. Taal In Media : TIM 2014

    NARCIS (Netherlands)

    Reker, Siemon

    2014-01-01

    In deze rubriek worden beschouwinkjes op basis van uitingen in (of op) media geplaatst, geschreven door medewerkers van het Bureau Groninger Taal en Cultuur. Blijf via Twitter (@BGTCRuG) op de hoogte van het verschijnen van nieuwe TIM's.

  11. Taal In Media : TIM 2015

    NARCIS (Netherlands)

    Reker, Siemon

    2015-01-01

    In deze rubriek worden beschouwinkjes op basis van uitingen in (of op) media geplaatst, geschreven door medewerkers van het Bureau Groninger Taal en Cultuur. Blijf via Twitter (@BGTCRuG) op de hoogte van het verschijnen van nieuwe TIM's.

  12. Rao, Prof. Madan

    Indian Academy of Sciences (India)

    Elected: 2011 Section: Physics. Rao, Prof. Madan Ph.D. (IISc). Date of birth: 11 July 1960. Specialization: Nonequilibrium Statistical Mechanics, Soft Condensed Matter Physics, Biological Physics Address: Theoretical Physics Group, Raman Research Institute, CV Raman Avenue, Bengaluru 560 080, Karnataka Contact:

  13. Pandit, Prof. Aniruddha Bhalachandra

    Indian Academy of Sciences (India)

    Pandit, Prof. Aniruddha Bhalachandra Ph.D. (Mumbai), FNAE, FNA, FNASc, FTWAS. Date of birth: 7 December 1957. Specialization: Design of Multiphase Reactors, Cavitation Phenomena and Environmental & Energy Engineering Address: Dean (HR), Institute of Chemical Technology, N.P. Marg, Matunga, Mumbai 400 ...

  14. Ganesh, Prof. Subramaniam

    Indian Academy of Sciences (India)

    Elected: 2016 Section: Medicine. Ganesh, Prof. Subramaniam Ph.D. (Banaras), FNASc. Date of birth: 23 May 1968. Specialization: Human Molecular Genetics, Neurobiology of Disease, Stress Biology Address: Department of Biological Sciences & Bioengineering, Indian Institute of Technology, Kanpur 208 016, U.P.

  15. Krishna, Prof. Padmanabhan

    Indian Academy of Sciences (India)

    Elected: 1979 Section: Physics. Krishna, Prof. Padmanabhan Ph.D. (Banaras), FNA. Date of birth: 13 January 1938. Specialization: Crystallography, Imperfection in Solids, Education and Science & Society Address: Adviser, Krishnamurti Foundation India, Rajghat Education Centre, Rajghat Fort, Varanasi 221 001, U.P.

  16. Dash, Prof. Debabrata

    Indian Academy of Sciences (India)

    Dash, Prof. Debabrata Ph.D. (BHU). Date of birth: 12 April 1958. Specialization: Cell Biology, Signal Transduction, Nanobiotechnology Address: Head, Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221 005, U.P.. Contact: Office: (0542) 670 3243. Residence: (0542) 236 9300

  17. Kumar, Prof. Har Darshan

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1975 Section: Plant Sciences. Kumar, Prof. Har Darshan Ph.D. (London), FNA, FNASc. Date of birth: 25 February 1934. Specialization: Algology, Microbial Biotechnology, Genetics, Ecology and Environment Address: Mrigtrishna, B.32/32, H.K. 214, Saketnagar Colony, Naria, Varanasi 221 005, U.P.

  18. Jayaraman, Prof. Achuthan

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2006 Section: Earth & Planetary Sciences. Jayaraman, Prof. Achuthan Ph.D. (Gujarat). Date of birth: 21 June 1957. Specialization: Atmospheric Science, Aerosols and Radiative Transfer Address: Director, National Atmospheric Research Laboratory, P. B. No. 123, Tirupati - 517 502, A.P.. Contact:

  19. Rangaswamy, Prof. Nanjangud Sreekantaiah

    Indian Academy of Sciences (India)

    Elected: 1981 Section: Plant Sciences. Rangaswamy, Prof. Nanjangud Sreekantaiah Ph.D. (Delhi), FNA, FNASc. Date of birth: 8 May 1932. Specialization: Reproductive Physiology of Seed Plants, Plant Tissue Culture and Biotechnology Address: Apt. No. 241, III Floor, Block B-2, Kendriya Vihar, Bellary Road, Yelahanka, ...

  20. Tyagi, Prof. Akhilesh Kumar

    Indian Academy of Sciences (India)

    Elected: 2004 Section: Plant Sciences. Tyagi, Prof. Akhilesh Kumar Ph.D. (Delhi), FNA, FNASc, FNAAS, FTWAS. Date of birth: 15 May 1956. Specialization: Genomics, Regulation Biology and Biotechnology Address: Department of Plant Molecular Biology, University of Delhi - South Campus, Benito Juarez Road, New Delhi ...

  1. Chakravorty, Prof. Animesh

    Indian Academy of Sciences (India)

    Elected: 1975 Section: Chemistry. Chakravorty, Prof. Animesh Ph.D. (Calcutta), FNA, FTWAS Council Service: 1986-91. Date of birth: 30 June 1935. Specialization: Inorganic Chemistry Address: Flat 8/3, 6, Sunny Park, Ballygunge, Kolkata 700 019, W.B.. Contact: Residence: (033) 2485 8327. Mobile: 94338 01715

  2. Krebs, Prof. Hans Adolf

    Indian Academy of Sciences (India)

    Krebs, Prof. Hans Adolf Nobel Laureate (Medicine) - 1953. Date of birth: 25 August 1900. Date of death: 22 November 1981. YouTube; Twitter ... Summer Schools. Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach.

  3. Pauling, Prof. Linus Carl

    Indian Academy of Sciences (India)

    Pauling, Prof. Linus Carl Nobel Laureate (Chemistry) - 1954; Peace - 1962. Date of birth: 28 February 1901. Date of death: 19 August 1994 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  4. Pavlov, Prof. Ivan Petrovich

    Indian Academy of Sciences (India)

    Pavlov, Prof. Ivan Petrovich Nobel Laureate (Medicine) - 1904. Date of birth: 27 September 1849. Date of death: 27 February 1936. YouTube ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  5. Hardy, Prof. Godfrey Harold

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1935 Honorary. Hardy, Prof. Godfrey Harold. Date of birth: 7 February 1877. Date of death: 1 December 1947 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  6. Richardson, Prof. Owen Willians

    Indian Academy of Sciences (India)

    Richardson, Prof. Owen Willians Nobel Laureate (Physics) - 1928. Date of birth: 26 April 1879. Date of death: 15 February 1959. YouTube ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  7. Brillouin, Prof. Leon

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1939 Honorary. Brillouin, Prof. Leon. Date of birth: 7 August 1889. Date of death: 4 October 1969 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  8. Rouxel, Prof. Jean

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1994 Honorary. Rouxel, Prof. Jean. Date of birth: 24 February 1935. Date of death: 19 March 1998 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  9. Segre, Prof. Emilio Gino

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1971 Honorary. Segre, Prof. Emilio Gino. Date of birth: 1 February 1905. Date of death: 22 April 1989. YouTube; Twitter ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  10. Karrer, Prof. Paul

    Indian Academy of Sciences (India)

    Elected: 1947 Honorary. Karrer, Prof. Paul Nobel Laureate (Chemistry) - 1937. Date of birth: 21 April 1889. Date of death: 18 June 1971 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  11. Lundsgaard, Prof. Einar

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1966 Honorary. Lundsgaard, Prof. Einar. Date of birth: 12 February 1899. Date of death: 18 December 1968. YouTube ... Summer Schools. Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach.

  12. Bragg, Prof. William Henry

    Indian Academy of Sciences (India)

    Elected: 1935 Honorary. Bragg, Prof. William Henry Nobel Laureate (Physics) - 1915. Date of birth: 2 July 1862. Date of death: 10 March 1972 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  13. Pitzer, Prof. Kenneth Sanborn

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1986 Honorary. Pitzer, Prof. Kenneth Sanborn. Date of birth: 6 January 1914. Date of death: 26 December 1997 ... Summer Schools. Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach.

  14. Kock, Prof. Winston E.

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1970 Honorary. Kock, Prof. Winston E. Date of birth: 5 December 1909. Date of death: 25 November 1982. YouTube ... Summer Schools. Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach.

  15. Rutherford, Prof. Ernest (Lord)

    Indian Academy of Sciences (India)

    Rutherford, Prof. Ernest (Lord) Nobel Laureate (Chemistry) - 1908. Date of birth: 30 August 1871. Date of death: 19 October 1937. YouTube ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  16. Bawden, Prof. Frederick Charles

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1972 Honorary. Bawden, Prof. Frederick Charles. Date of birth: 18 August 1908. Date of death: 8 February 1972 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  17. Bridgman, Prof. Percy Williams

    Indian Academy of Sciences (India)

    Bridgman, Prof. Percy Williams Nobel Laureate (Physics) - 1946. Date of birth: 21 April 1882. Date of death: 20 August 1961. YouTube; Twitter ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  18. Russell, Prof. John

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Russell, Prof. John. Date of birth: 31 October 1872. Date of death: 12 July 1965 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  19. Anderson, Prof. Basil Williams

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1964 Honorary. Anderson, Prof. Basil Williams. Date of birth: 3 July 1901. Date of death: 24 February 1984. YouTube ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  20. Bovet, Prof. Daniel

    Indian Academy of Sciences (India)

    Elected: 1967 Honorary. Bovet, Prof. Daniel Nobel Laureate (Medicine) - 1957. Date of birth: 23 March 1907. Date of death: 8 April 1992 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  1. Morgan, Prof. Thomas Hunt

    Indian Academy of Sciences (India)

    Morgan, Prof. Thomas Hunt Nobel Laureate (Medicine) - 1933. Date of birth: 25 September 1866. Date of death: 4 December 1945. YouTube ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  2. Mecke, Prof. Reinhard

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1957 Honorary. Mecke, Prof. Reinhard. Date of birth: 14 July 1895. Date of death: 30 December 1969. YouTube; Twitter ... Summer Schools. Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach.

  3. Kastler, Prof. Alfred

    Indian Academy of Sciences (India)

    Elected: 1970 Honorary. Kastler, Prof. Alfred Nobel Laureate (Physics) - 1966. Date of birth: 3 May 1902. Date of death: 7 January 1984 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  4. Bunning, Prof. Erwing

    Indian Academy of Sciences (India)

    Elected: 1986 Honorary. Bunning, Prof. Erwing. Date of birth: 23 January 1906. Date of death: 4 October 1990. YouTube; Twitter; Facebook ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  5. Chapman, Prof. Sydney

    Indian Academy of Sciences (India)

    Elected: 1947 Honorary. Chapman, Prof. Sydney. Date of birth: 29 January 1888. Date of death: 16 June 1970. YouTube; Twitter; Facebook ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  6. Plyler, Prof. Earle Keith

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1962 Honorary. Plyler, Prof. Earle Keith. Date of birth: 26 April 1897. Date of death: 8 May 1976 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  7. Bowen, Prof. Ira Sprague

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1956 Honorary. Bowen, Prof. Ira Sprague. Date of birth: 21 December 1898. Date of death: 6 February 1973. YouTube ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  8. Sebastian, Prof. Kizhakeyil Lukose

    Indian Academy of Sciences (India)

    Sebastian, Prof. Kizhakeyil Lukose Ph.D. (IISc), FNA Council Service: 2016-. Date of birth: 18 November 1950. Specialization: Theoretical Chemistry and Chemistry of Interfaces Address: Department of Chemistry, Indian Institute of Technology, Ahalia Integrated Campus, Kozhippara Post, Palakkad 678 557, Kerala Contact:

  9. Indira Nath, Prof.

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1988 Section: Medicine. Indira Nath, Prof. M.D. (AIIMS), FRC Path., FAMS, FNA, FNASc, D.Sc. (h.c.) Council Service: 1992-94, 1998-2006; Vice-President 2001-2003. Date of birth: 14 January 1938. Specialization: Immunology, Leprosy and Pathology Address: 707, Sarvapriya ...

  10. Majumder, Prof. Partha Pratim

    Indian Academy of Sciences (India)

    Majumder, Prof. Partha Pratim Ph.D. (ISI, Calcutta), FNA, FNASc, FTWAS Council Service: 2016-. Date of birth: 6 September 1952. Specialization: Biostatistics, Human Genetics and Population Genetics Address: Distinguished Professor, National Institute of Biomedical Genomics, Post Netaji Subhas Sanitorium, Kalyani 741 ...

  11. Chandrashekaran, Prof. Maroli Krishnayya

    Indian Academy of Sciences (India)

    Chandrashekaran, Prof. Maroli Krishnayya Ph.D. (Madras), D.Sc. (Madurai), FNA, FNASc, FTWAS Council Service: 1992-97. Date of birth: 4 January 1937. Date of death: 2 July 2009. Specialization: Chronobiology and Animal Behaviour Last known address: Evolutionary and Organismal Biology Unit, Jawaharlal Nehru ...

  12. Adiga, Prof Perdur Radhakantha

    Indian Academy of Sciences (India)

    Adiga, Prof Perdur Radhakantha Ph.D. (IISc), FNA. Date of birth: 5 May 1935. Date of death: 13 September 2006. Specialization: Endocrine Biochemistry, Reproductive Physiology & Growth, and Differentiation Last known address: Emeritus Professor, Department of Molecular Reproduction and Developmental, Genetics, ...

  13. Bhattacharjee, Prof. Somendra Mohan

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2000 Section: Physics. Bhattacharjee, Prof. Somendra Mohan Ph.D. (Carnegie Mellon), FNA. Date of birth: 24 January 1957. Specialization: Statistical Physics and Condensed Matter Physics Address: Institute of Physics, Sachivalaya Marg, Bhubaneswar 751 005, Orissa Contact:

  14. Agarwal, Prof Girish S

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  15. Aswathanarayana, Prof. Uppugunduri

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1976 Section: Earth & Planetary Sciences. Aswathanarayana, Prof. Uppugunduri D.Sc. (Andhra), FNA, FTWAS. Date of birth: 1 July 1928. Date of death: 7 March 2016. Specialization: Nuclear Geology, Natural Resources Management and Environmental Geochemistry Last known address: Shanti ...

  16. Mishra, Prof. Santosh Kumar

    Indian Academy of Sciences (India)

    Elected: 1987 Section: Earth & Planetary Sciences. Mishra, Prof. Santosh Kumar Ph.D. (Pune), FNA. Date of birth: 1 March 1941. Specialization: Dynamic Meteorology and Numerical Modelling of the Atmosphere Address: Flat No. 4, 163/24 Mausam Vihar, Park Avenue, Off DP Road, Aundh, Pune 411 007, Maharashtra

  17. Gadgil, Prof. Sulochana

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1985 Section: Earth & Planetary Sciences. Gadgil, Prof. Sulochana Ph.D. (Harvard), FNA. Date of birth: 7 June 1944. Specialization: Meteorology, Oceanography and Evolutionary Biology Address: A 18, Spring Flowers, Panchavati, Pashan, Pune 411 008, Maharashtra Contact:

  18. Bhattacharyya, Prof. Prabhat Kumar

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1976 Section: Chemistry. Bhattacharyya, Prof. Prabhat Kumar Ph.D. (Illinois), FNA. Date of birth: 22 October 1921. Date of death: 16 April 1996. Specialization: Bio-organic Chemistry and Chemical Microbiology Address: 177, Jodhpur Park, Flat - 1S, Calcutta 700 068. YouTube; Twitter; Facebook ...

  19. Panda, Prof. Sudhakar

    Indian Academy of Sciences (India)

    Panda, Prof. Sudhakar Ph.D. (IoP, Bhubaneswar), FNA, FNASc. Date of birth: 23 February 1959. Specialization: High Energy Physics, String Theory, Cosmology, Quantum Field Theory Address: Director, Institute of Physics, Sachivalaya Marg, Bhubaneswar 751 005, Orissa Contact: Office: (0674) 230 1825, 230 6404

  20. Narayan, Prof. Ramesh

    Indian Academy of Sciences (India)

    Narayan, Prof. Ramesh FRS. Date of birth: 25 September 1950. Address: Harvard Smithsonian Centre for, Astrophysics, Harvard University, 60, Garden Street, MS-51, Cambridge, MA 02138, USA Contact: Office: (+1-617) 496 9393. Fax: (+1-617) 495 7053. Email: rnarayan@cfa.harvard.edu. YouTube; Twitter; Facebook ...

  1. Nicolaou, Prof. Kyriacos Costa

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2007 Honorary. Nicolaou, Prof. Kyriacos Costa. Date of birth: 1946. Address: Department of Chemistry & BRC, Rice University, 6100, Main Street, MS 602, Houston, TX 77005, U.S.A.. Contact: Residence: (+1-713) 348 8860. Fax: (+1-713) 348 8865. Email: kcn@rice.edu. YouTube; Twitter; Facebook ...

  2. Bai, Prof. Chunli

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2009 Honorary. Bai, Prof. Chunli. Date of birth: 1953. Address: Executive Vice-President, Chinese Academy of Sciences, 52, Sanlihe Road, Beijing 100864, China Contact: Office: (+86-10) 6859 7606. Fax: (+86-10) 6852 6316. Email: clbai@cas.cn. YouTube; Twitter; Facebook ...

  3. Chakravarty, Prof. Charusita

    Indian Academy of Sciences (India)

    Chakravarty, Prof. Charusita Ph.D. (Cambridge). Date of birth: 5 May 1964. Date of death: 29 March 2016. Specialization: Chemical Physics, Theoretical & Computational Chemistry Last known address: Professor, Department of Chemistry, Indian Institute of Technology, New Delhi 110 016, U.T.. YouTube; Twitter; Facebook ...

  4. Bloembergen, Prof. Nicolaas

    Indian Academy of Sciences (India)

    Bloembergen, Prof. Nicolaas Nobel Laureate (Physics) - 1981. Date of birth: 11 March 1920. Address: Optical Sciences Center, University of Arizona, 1630E, University Blvd., Tucson, AZ 85721, U.S.A.. Contact: Residence: (+1-520) 647 3772. Email: nbloembergen@optics.arizona.edu. YouTube; Twitter; Facebook; Blog ...

  5. Gross, Prof. David J

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2007 Honorary. Gross, Prof. David J. Date of birth: 1941. Address: Kavli Institute for Theoretical, Physics, University of California, Santa Barbara, CA 93106-4030, U.S.A.. Contact: Office: (+1-805) 893 7337. Residence: (+1-805) 963 8324. Fax: (+1-893) 893 2431. Email: gross@kitp.ucsb.edu. YouTube ...

  6. Hartl, Prof. Daniel L

    Indian Academy of Sciences (India)

    Hartl, Prof. Daniel L. Date of birth: 1 January 1943. Address: Higgins Professor of Biology, Dept. of Organismic & Evolutionary, Biology, The Biological Lab., Harvard University, 16 Divinity Ave, Cambridge, MA 02138, USA Contact: Office: (+1-617) 496 3917. Email: dhartl@oeb.harvard.edu. YouTube; Twitter; Facebook; Blog ...

  7. Hagenmuller, Prof. Paul

    Indian Academy of Sciences (India)

    Hagenmuller, Prof. Paul. Date of birth: 3 August 1921. Address: Honorary Director, ICMCB-CNRS, Bordeaux University, 87 Avenue Dr Albert Schweitzer, 33608 Pessac Cedex, France Contact: Office: (+33-5) 40 00 63 25. Fax: (+33-5) 40 00 63 24. Email: hagen@icmcb.u-bordeaux.fr. YouTube; Twitter; Facebook; Blog ...

  8. Venkataramana, Prof. Tyakal Nanjundiah

    Indian Academy of Sciences (India)

    Venkataramana, Prof. Tyakal Nanjundiah Ph.D. (Mumbai), FNA. Date of birth: 14 February 1958. Specialization: Monodromy Groups, Rigidity & Arithmeticity of Lattices, Cohomology of Arithmetic Groups and Shimura Varieties Address: Professor, School of Mathematics, Tata Institute of Fundamental Research, Homi Bhabha ...

  9. Bhattacharyya, prof. Tirthankar

    Indian Academy of Sciences (India)

    Elected: 2016 Section: Mathematical Sciences. Bhattacharyya, prof. Tirthankar Ph.D. (ISI). Date of birth: 7 February 1968. Specialization: Functional Analysis, Hilbert Space, Operator Theory, Several Complex Variables Address: Department of Mathematics, Indian Institute of Science, Bengaluru 560 012, Karnataka Contact:

  10. Rajan, Prof. Conjeeveram Srirangachari

    Indian Academy of Sciences (India)

    Rajan, Prof. Conjeeveram Srirangachari Ph.D. (Bombay), FNA. Date of birth: 21 May 1961. Specialization: Automorphic Forms, Arithmetic Geometry and Representation Theory Address: Professor, School of Mathematics, Tata Institute of Fundamental Research, Homi Bhabha Road, Mumbai 400 005, Maharashtra Contact:

  11. Bhattacharyya, Prof. Kankan

    Indian Academy of Sciences (India)

    Bhattacharyya, Prof. Kankan Ph.D. (Calcutta), FNA, FNASc, FTWAS. Date of birth: 17 November 1954. Specialization: Femtosecond Laser Spectroscopy, Single Molecule Spectroscopy Address: Department of Chemistry, Indian Institute of Science Education & Research, Bypass Road, Bhauri, Bhopal 462 066, M.P.. Contact:

  12. Ananthakrishnan, Prof. Taracad Narayanan

    Indian Academy of Sciences (India)

    Ananthakrishnan, Prof. Taracad Narayanan Ph.D. and D.Sc. (Madras), FNA, FNAAS Council Service: 1980-82. Date of birth: 15 December 1925. Date of death: 7 August 2015. Specialization: Entomology, Cecidology and Chemical Ecology Last known address: 4312, Zenith Avenue South, Minneapolis, MN 55410, USA.

  13. Einstein, Prof. Albert

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1936 Honorary. Einstein, Prof. Albert Nobel Laureate (Physics) - 1921. Date of birth: 14 March 1879. Date of death: 18 April 1955. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science ...

  14. Anand, Prof. Anuranjan

    Indian Academy of Sciences (India)

    Elected: 2011 Section: Medicine. Anand, Prof. Anuranjan Ph.D. (IISc), FNASc, FNA. Date of birth: 5 April 1965. Specialization: Human Genetics & Genomics, Neurogenetics, Developmental Genetics Address: Molecular Biology & Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bengaluru ...

  15. Rajaraman, Prof. Vaidyeswaran

    Indian Academy of Sciences (India)

    Rajaraman, Prof. Vaidyeswaran S.M. (MIT), Ph.D. (Wisconsin), FNA, FNAE, FNASc. Date of birth: 8 September 1933. Specialization: Computer Science and Information Systems Design Address: Honorary Professor, Supercomputer Education and Research Centre, Indian Institute of Science, Bengaluru 560 012, Karnataka

  16. Das, Prof. Prosad Kumar

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1975 Section: Earth & Planetary Sciences. Das, Prof. Prosad Kumar D.Phil. (Calcutta), FNA Council Service: 1980-82. Date of birth: 20 May 1926. Date of death: 14 January 2011. Specialization: Numerical Weather Prediction, Ocean-Atmosphere Coupling, Storm Surges and Dynamic Meteorology

  17. Blumberg, Prof. Baruch Samuel

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1987 Honorary. Blumberg, Prof. Baruch Samuel Nobel Laureate (Medicine) - 1976. Date of birth: 28 July 1925. Date of death: 5 April 2011. Last known address: Distinguished Scientist, Fox Chase Cancer Center, 333, Cottman Avenue, Philadelphia, PA 19111, U.S.A.. YouTube; Twitter; Facebook ...

  18. Bhattacharya, Prof. Alok

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2015 Section: General Biology. Bhattacharya, Prof. Alok Ph.D. (JNU), FNA. Date of birth: 2 February 1951. Specialization: Molecular Parasitology, Computational Genomics Address: School of Life Sciences, Jawaharlal Nehru University, New Delhi 110 067, U.T.. Contact: Office: (011) 2670 4516

  19. Sharma, Prof. Man Mohan

    Indian Academy of Sciences (India)

    Sharma, Prof. Man Mohan Ph.D. (Cantab), D.Sc. (h.c.), D.Engg. (h.c.), LL.D. (h.c.), FNA, FRS Council Service: 1986-88. Date of birth: 1 May 1937. Specialization: Multiphase Reactions/Reactors, Separations Address: 2/3, Jaswant Baug, Behind Akbarallys, V.N. Purav Marg, Chembur, Mumbai 400 071, Maharashtra Contact:

  20. Ramakrishnan, Prof. Palayanoor Sivaswamy

    Indian Academy of Sciences (India)

    Ramakrishnan, Prof. Palayanoor Sivaswamy Ph.D. (Banaras), FNA, FNASc, FTWAS. Date of birth: 24 December 1936. Specialization: Socio-ecology, Environment and Sustainable Development Address: INSA Honorary Scientist, School of Environmental Sciences, Jawaharlal Nehru University, New Delhi 110 067, U.T.

  1. Punniyamurthy, Prof. Tharmalingam

    Indian Academy of Sciences (India)

    Punniyamurthy, Prof. Tharmalingam Ph.D. (IIT, Kanpur), FRSC. Date of birth: 3 June 1964. Specialization: Synthetic Organic Chemistry Address: Department of Chemistry, Indian Institute of Technology, Guwahati 781 039, Assam Contact: Office: (0361) 258 2309. Residence: (0361) 258 4309. Mobile: 94351 02462

  2. Chowdhury, Prof. Debashish

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2004 Section: Physics. Chowdhury, Prof. Debashish Ph.D. (IIT, Kanpur), FNASc, FNA. Date of birth: 10 September 1957. Specialization: Statistical Physics, Condensed Matter Physics and Biological Physics Address: Professor, Department of Physics, Indian Institute of Technology, ...

  3. Gadre, Prof. Shridhar Ramchandra

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1991 Section: Chemistry. Gadre, Prof. Shridhar Ramchandra Ph.D. (IIT, Kanpur), FNA. Date of birth: 20 May 1950. Specialization: Quantum Chemistry and Computer Applications Address: Interdisciplinary School of Scientific Computing, University of Pune, Ganeshkhind, Pune 411 007, Maharashtra

  4. Marimuthu, Prof. Ganapathy

    Indian Academy of Sciences (India)

    Marimuthu, Prof. Ganapathy Ph.D. (MKU), D.Sc. (MKU), FNASc, FNA. Date of birth: 25 February 1954. Specialization: Animal Behaviour and Chronobiology Address: INSA Senior Scientist, Department of Animal Behaviour and Physiology, School of Biological Sciences, Madurai Kamaraj University, Madurai 625 021, T.N.

  5. Sarkar, Prof. Chitra

    Indian Academy of Sciences (India)

    Sarkar, Prof. Chitra M.B.B.S. (Bangalore), M.D. (AIIMS), FRC Path. (London), FNASc, FAMS, FNA Council Service: 2013-15. Date of birth: 11 September 1955. Specialization: Neuropathology Address: Professor, Department of Pathology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, U.T.. Contact:

  6. Ramakrishna, Prof. Balakrishnan Siddartha

    Indian Academy of Sciences (India)

    Ramakrishna, Prof. Balakrishnan Siddartha MD, DM & Ph.D. (Madras), FAMS, FNA. Date of birth: 26 October 1952. Specialization: Gastroenterology, Nutrition, Inflammatory Bowel Disease, Gastrointestinal Microbiome Stem Cells Address: Flat No. 202-2-03, GVSPL Green Park, 342, Vaidyanathan Street, Nungambakkam, ...

  7. Radhakrishnan, Prof. Jaikumar

    Indian Academy of Sciences (India)

    Radhakrishnan, Prof. Jaikumar Ph.D. (Rutgers), FNA. Date of birth: 30 May 1964. Specialization: Algorithms, Information Theory, Computational Complexity, Combinatorics and Quantum Computing Address: Professor, School of Technology & Computer Science, Tata Institute of Fundamental Research, Homi Bhabha Road, ...

  8. Radhakrishnan, Prof. Thavarool Puthiyedath

    Indian Academy of Sciences (India)

    Radhakrishnan, Prof. Thavarool Puthiyedath Ph.D. (Princeton), FNA, FNASc. Date of birth: 25 May 1960. Specialization: Materials Chemistry Address: Professor, School of Chemistry, University of Hyderabad, Hyderabad 500 046, A.P.. Contact: Office: (040) 2313 4827, (040) 2301 1068. Residence: (040) 2980 2989

  9. Chakravarti, Prof. Aravinda

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2008 Honorary. Chakravarti, Prof. Aravinda. Date of birth: 6 February 1954. Address: Director - CCDG, McKusick-Nathans Inst. of Genetic, Medicine, Johns Hopkins Univ., School of Medicine, 733 N.Broadway, Baltimore, MD 21205, USA Contact: Office: (+1-410) 502 7525. Fax: (+1-410) 502 7544

  10. Ganeshaiah, Prof. Kotiganahalli Narayanagowda

    Indian Academy of Sciences (India)

    Elected: 1992 Section: Plant Sciences. Ganeshaiah, Prof. Kotiganahalli Narayanagowda Ph.D. (UAS, Bangalore), FNA, FNAAS. Date of birth: 10 May 1953. Specialization: Plant Evolutionary Biology, Plant Genetics & Breeding, Foraging Ecology of Ants and Biodiversity & Conservation Address: 7, Pungavee Santosh Vihar, ...

  11. Ananthakrishnan, Prof. Ramakrishnaiyer

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1938 Section: Earth & Planetary Sciences. Ananthakrishnan, Prof. Ramakrishnaiyer D.Sc. (Madras), FNA 1962-64. Date of birth: 11 April 1911. Date of death: 21 July 1998. Specialization: Solar Physics and Atmospheric Physics Address: Flat No. 9, Praram Apartments, Lakaki Road, Pune 411 016.

  12. Moorthy, Prof. Jarugu Narasimha

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2010 Section: Chemistry. Moorthy, Prof. Jarugu Narasimha Ph.D. (IISc). Date of birth: 1 July 1964. Specialization: Organic Photochemistry, Supramolecular Chemistry, Organic Synthesis Address: Department of Chemistry, Indian Institute of Technology, Kanpur 208 016, U.P.

  13. Ramasesha, Prof. Suryanarayana Sastry

    Indian Academy of Sciences (India)

    Ramasesha, Prof. Suryanarayana Sastry Ph.D. (IIT, Kanpur), FNA, FTWAS. Date of birth: 16 January 1950. Specialization: Many-Body Quantum Chemistry, Organic Solids, Molecular Electronics, Molecular Magnetism and Nonlinear Optics Address: Professor, Solid State & Structural Chemistry Unit, Indian Institute of Science ...

  14. Sankararaman, Prof. Sethuraman

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2017 Section: Chemistry. Sankararaman, Prof. Sethuraman Ph.D. (Victoria). Date of birth: 15 October 1957. Specialization: Organometallic Chemistry, Organic Photochemistry, Time-resolved Spectroscopy Address: Department of Chemistry, Indian Institute of Technology, Chennai 600 036, T.N.

  15. Vanninathan, Prof. Muthusamy

    Indian Academy of Sciences (India)

    Elected: 1997 Section: Mathematical Sciences. Vanninathan, Prof. Muthusamy Ph.D. (Pierre et Marie Curie, Paris). Date of birth: 15 May 1951. Specialization: Fluid-Structure Interactions, Partial Differential Equations, Numerical Analysis, Asymptotic Analysis, Homogenization and Control of PDE Address: Department of ...

  16. Sane, Prof. Sharad Sadashiv

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2010 Section: Mathematical Sciences. Sane, Prof. Sharad Sadashiv Ph.D. (IIT, Bombay). Date of birth: 20 November 1950. Specialization: Finite Geometries, Design Theory and Graph Theory Address: Department of Mathematics, Indian Institute of Technology, Powai, Mumbai 400 076, Maharashtra

  17. Bhosle, Prof. Ushadevi Narendra

    Indian Academy of Sciences (India)

    Elected: 2000 Section: Mathematical Sciences. Bhosle, Prof. Ushadevi Narendra Ph.D. (Bombay), FNASc, FNA. Date of birth: 30 March 1949. Specialization: Algebraic Geometry Address: Flat No. 256, Jal Vayu Towers, NGEF Layout, Bennigannahalli, Bengaluru 560 038, Karnataka Contact: Residence: 99306 41136

  18. Johri, Prof. Man Mohan

    Indian Academy of Sciences (India)

    Elected: 1983 Section: General Biology. Johri, Prof. Man Mohan Ph.D. (Delhi), FNA. Date of birth: 15 September 1940. Specialization: Plant Biochemistry, Molecular Biology of Plants and Genetic Engineering Address: Flat No. 32, New Cosmos CHSL, Juhu-Versova Link Road, Andheri (W), Mumbai 400 053, Maharashtra

  19. Khare, Prof. Avinash Vasant

    Indian Academy of Sciences (India)

    Elected: 1991 Section: Physics. Khare, Prof. Avinash Vasant Ph.D. (Calcutta), FNA. Date of birth: 20 June 1945. Specialization: High Energy & Elementary Particle Physics, Supersymmetric Quantum Mechanics and Nonlinear Dynamics Address: INSA Senior Scientist, Department of Physics, University of Pune, Ganeshkhind ...

  20. Narasimhan, Prof. Mudumbai Seshachalu

    Indian Academy of Sciences (India)

    Narasimhan, Prof. Mudumbai Seshachalu Ph.D. (Mumbai), FNA, FNASc, FRS Council Service: 1977-82; Vice-President: 1980-82. Date of birth: 7 June 1932. Specialization: Algebraic & Differential Geometry and Analysis Address: 9, Guruparadise Apartments, 24, 4th Main Road, Amarjyoti Layout, Sanjay Nagar, Bengaluru ...

  1. Ila, Prof. Hiriyakkanavar

    Indian Academy of Sciences (India)

    Elected: 1991 Section: Chemistry. Ila, Prof. Hiriyakkanavar Ph.D. (IIT, Kanpur), FNA. Date of birth: 11 September 1944. Specialization: Synthetic Organic Chemistry, Heterocyclic Chemistry, Medicinal Chemistry Address: Apt. 002, Block VIII, Heritage Estate, Doddaballapur Road, Yelahanka, Bengaluru 560 064, Karnataka

  2. Kulkarni, Prof. Sulabha Kashinath

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2004 Section: Physics. Kulkarni, Prof. Sulabha Kashinath Ph.D. (Pune), FNASc, FNA. Date of birth: 1 June 1949. Specialization: Surface Physics, Materials Science and Nanoscience Address: Centre for Materials for Electronics Technology, Off Dr Homi Bhabha Road, Panchwati, ...

  3. About Prof. Satish Dhawan

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 8; Issue 10. About Prof. Satish Dhawan. K Kasturirangan. General Article Volume 8 Issue 10 October 2003 pp 48-55. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/008/10/0048-0055. Keywords.

  4. Menon, Prof. Thuppalay Kochugovinda

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1974 Section: Physics. Menon, Prof. Thuppalay Kochugovinda Ph.D. (Harvard). Date of birth: 19 December 1928. Specialization: Astrophysics Address: 106-2803, 41st Avenue, Vancouver, British Columbia V6N 4B4, Canada Contact: Office: (+1-604) 822 0330. Residence: (+1-604) 266 1789

  5. Chander, Prof. Ramesh

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1993 Section: Earth & Planetary Sciences. Chander, Prof. Ramesh Ph.D. (Columbia). Date of birth: 6 September 1939. Specialization: Seismology and Geophysics Address: House No. 290, Sector 4, Mansa Devi Complex, Panchkula 134 114, Haryana Contact: Residence: (0172) ...

  6. Ramachandran, Prof. Arcot

    Indian Academy of Sciences (India)

    Elected: 1974 Section: Engineering & Technology. Ramachandran, Prof. Arcot Ph.D. (Purdue), D.Sc. (h.c.), D.lng. (h.c.), D.Eng. (h.c.), FNA, FNAE. Date of birth: 6 April 1923. Specialization: Energy, Heat and Mass Transfer Address: No. 3, Crescent Road, Bengaluru 560 001, Karnataka Contact: Residence: (080) 2225 5780

  7. Ramachandran, Prof. Raghavan

    Indian Academy of Sciences (India)

    Ramachandran, Prof. Raghavan Ph.D. (Chicago), FNASc. Date of birth: 15 February 1940. Specialization: Particle Physics Address: Flat 12, Khagol Society, Panchvati, Pashan, Pune 411 008, Maharashtra Contact: Residence: (020) 6607 5892. Mobile: 94220 04597. Email: rr_1940@yahoo.co.in, rr@imsc.res.in. YouTube ...

  8. Bose, Prof. Sujit Kumar

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1990 Section: Mathematical Sciences. Bose, Prof. Sujit Kumar D.Sc. (Calcutta). Date of birth: 10 October 1938. Specialization: Applied Mathematics, Solid Mechanics, Fluid Mechanics and Sediment Transport Address: BE-188, Salt Lake City, Kolkata 700 064, W.B.. Contact: Residence: 79805 77636

  9. Mahadevan, Prof. Priya

    Indian Academy of Sciences (India)

    Elected: 2014 Section: Physics. Mahadevan, Prof. Priya Ph.D. (IISc). Date of birth: 19 August 1970. Specialization: Electronic Structure of Materials, Magnetism, Nanostructure Materials Address: Associate Professor, SN Bose National Centre for Basic Sciences, JD Block, Sector 3, Salt Lake, Kolkata 700 098, W.B.. Contact:

  10. Sutherland, Prof. Bill

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2000 Honorary. Sutherland, Prof. Bill. Date of birth: 1942. Address: Department of Physics, University of Utah, 115 S 1400 E Rm 201, Salt Lake City, UT 8412-0830, U.S.A.. Contact: Office: (+1-801) 581 6424. Residence: (+1-801) 355 8342. Fax: (+1-801) 581 4801. Email: suther@physics.utah.edu, ...

  11. Rao, Prof. Sumathi

    Indian Academy of Sciences (India)

    Rao, Prof. Sumathi Ph.D. (SUNY, Stony Brook), FNASc. Date of birth: 5 December 1956. Specialization: Theoretical Condensed Matter Physics, Quantum field Theory Address: Harish Chandra Research Institute, Chhatnag Road, Jhusi, Allahabad 211 019, U.P.. Contact: Office: (0532) 227 4303. Residence: (0532) 227 4002

  12. Balaji, Prof. Vikraman

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2007 Section: Mathematical Sciences. Balaji, Prof. Vikraman Ph.D. (Madras). Date of birth: 15 September 1962. Specialization: Algebraic Geometry, Representation Theory and Topology Address: Chennai Mathematical Institute, H1, Sipcot IT Park, Padur Post, Siruseri, Chennai 603 103, T.N.. Contact ...

  13. Venkataraman, Prof. Ganesan

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  14. Vankar, Prof. Yashwant Dattatraya

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  15. Bapat, Prof. Ravindra Bhalchandra

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  16. Kodiyalam, Prof. Vijay

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  17. Goswami, Prof. Sreebrata

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  18. Ghosh, Prof. Sundargopal

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  19. Parthasarathy, Prof. Kalyanapuram Rangachari

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  20. Dasgupta, Prof. Indranil

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  1. Pontocorvo, Prof. Goido

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1984 Honorary. Pontocorvo, Prof. Goido. Date of birth: 29 November 1907. Date of death: 25 September 1999. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. New Fellows and Honorary Fellow. Posted on 1 January 2018. List of Fellows and Honorary Fellow elected ...

  2. Haddon, Prof. Alfred Cort

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1936 Honorary. Haddon, Prof. Alfred Cort. Date of birth: 24 May 1855. Date of death: 20 April 1940. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. New Fellows and Honorary Fellow. Posted on 1 January 2018. List of Fellows and Honorary Fellow elected during ...

  3. Ghosh, Prof. Anish

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2018 Section: Mathematical Sciences. Ghosh, Prof. Anish Ph.D. (Brandeis). Date of birth: 25 December 1979. Specialization: Ergodic Theory, Lie Groups, Number Theory Address: School of Mathematics, Tata Institute of Fundamental Research, Homi Bhabha Road, Mumbai 400 005, Maharashtra

  4. Prasad, Prof. Dipendra

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1995 Section: Mathematical Sciences. Prasad, Prof. Dipendra Ph.D. (Harvard), FNA, FNASc. Date of birth: 22 March 1960. Specialization: Automorphic Forms and Number Theory Address: Distinguished Professor, School of Mathematics, Tata Institute of Fundamental Research, Homi Bhabha Road, ...

  5. Khare, Prof. Avinash

    Indian Academy of Sciences (India)

    Khare, Prof. Avinash Ph.D. (PRL), FNA, FNASc. Date of birth: 23 July 1954. Specialization: Plasma Physics, Statistical Mechanics, Critical Phenomena, Plasma Astrophysics Address: Department of Physics & Astrophysics, University of Delhi, Delhi 110 007, U.T.. Contact: Office: (011) 2766 7155. Residence: (011) 2766 6242

  6. Mahapatra, Prof. Souvik

    Indian Academy of Sciences (India)

    Elected: 2018 Section: Engineering & Technology. Mahapatra, Prof. Souvik Ph.D. (IIT, Mumbai), FNAE, FIEEE. Date of birth: 26 October 1970. Specialization: Microelectronics & VLSI, Semiconductor Devices, Device Circuit Reliability Address: Department of Electrical Engineering, Indian Institute of Technology, Powai, ...

  7. Sane, Prof. Sanjay Prafullachandra

    Indian Academy of Sciences (India)

    Sane, Prof. Sanjay Prafullachandra Ph.D. (Univ. Calif., Berkeley). Date of birth: 12 September 1970. Specialization: Neuroethology, Biomechanics, Fluid Mechanics Address: National Centre for Biological Sciences, GKVK Campus, Bengaluru 560 065, Karnatka Contact: Office: (080) 2366 7020. Residence: (080) 4097 0586

  8. Bhargava, Prof. Balram

    Indian Academy of Sciences (India)

    Elected: 2018 Section: Medicine. Bhargava, Prof. Balram MD & DM (Lucknow), FNASc, FAMS, FRCP. Date of birth: 21 July 1961. Specialization: Cardiology, Medtech Innovation, Public Health Address: Department of Cardiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, U.T.. Contact:

  9. Sharma, Prof. Archana

    Indian Academy of Sciences (India)

    Annual Meetings · Mid Year Meetings · Discussion Meetings · Public Lectures · Lecture Workshops · Refresher Courses · Symposia · Live Streaming. Home; Fellowship. Fellow Profile. Elected: 1977 Section: Plant Sciences. Sharma, Prof. Archana Ph.D., D.Sc. (Calcutta), FNA, FNASc. Date of birth: 16 February 1932

  10. Prof. Dipankar Chatterji

    Indian Academy of Sciences (India)

    Elected: 1994 Section: General Biology. Chatterji, Prof. Dipankar Ph.D. (IISc), FNA, FNASc, FTWAS Council Service: 2007-; Secretary 2010-12; President: 2013-2015. Date of birth: 20 April 1951. Specialization: Molecular Biology, Biophysical Chemistry and Biomolecular Spectroscopy Address: Honorary Professor ...

  11. Shaila, Prof. Melkote Subbarao

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1993 Section: General Biology. Shaila, Prof. Melkote Subbarao Ph.D. (IISc). Date of birth: 10 October 1945. Specialization: Molecular Virology and Viral Immunology Address: Professor Emeritus, Department of Microbiology and Cell Biology, Indian Institute of Science, Bengaluru 560 012, Karnataka

  12. Ramdorai, Prof. Sujatha

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2004 Section: Mathematical Sciences. Ramdorai, Prof. Sujatha Ph.D. (Bombay), FNASc, FNA. Date of birth: 23 May 1962. Specialization: Algebra, Quadratic Forms, Number Theory and Iwasawa Theory Address: Professor, Department of Mathematics, University of British Columbia, ...

  13. Askey, Prof. Richard Allen

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1988 Honorary. Askey, Prof. Richard Allen. Date of birth: 4 June 1933. Address: 5915, American Parkway, Apt. 228, Madison, WI 43718, U.S.A.. Contact: Office: (+1-608) 262 2880. Residence: (+1-608) 233 7900. Fax: (+1-608) 263 8891. Email: askey@math.wisc.edu. YouTube; Twitter; Facebook ...

  14. Ramaswamy, Prof. Mythily

    Indian Academy of Sciences (India)

    Ramaswamy, Prof. Mythily Ph.D. (Paris), FNASc. Date of birth: 6 June 1954. Specialization: Nonlinear Functional Analysis, Partial Differential Equations, and Applications to Control Problems Address: Professor, TIFR Centre for Applicable Mathematics, P.B. No. 6503, Sharada Nagar, Bengaluru 560 065, Karnataka Contact:

  15. Adimurthi, Prof. Adi

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1996 Section: Mathematical Sciences. Adimurthi, Prof. Adi Ph.D. (Mumbai), FNA, FNASc. Date of birth: 19 March 1952. Specialization: Nonlinear Differential Equations Address: TIFR Centre for Applicable Mathematics, P.B. No. 6503, Sharada Nagar, Bengaluru 560 065, Karnataka

  16. Balasubramanian, Prof. Ramachandran

    Indian Academy of Sciences (India)

    Elected: 1987 Section: Mathematical Sciences. Balasubramanian, Prof. Ramachandran Ph.D. (Mumbai), FNA, FNASc. Council Service: 2007-2009. Date of birth: 15 March 1951. Specialization: Analytic Number Theory Address: Professor, The Institute of Mathematical Sciences, CIT Campus, Taramani, Chennai 600 113, ...

  17. Chaudhuri, Prof. Mihir Kanti

    Indian Academy of Sciences (India)

    Chaudhuri, Prof. Mihir Kanti Ph.D. (IIT, Kharagpur), Dr rer nat (FRG), FNA. Date of birth: 21 July 1947. Specialization: Synthesis, Structure & Reactivity, Newer Reagents and Methodologies and Green Chemical Technology Address: Adviser (Education), Government of Assam, Sachivalaya, Dispur, Guwahati 781 006, Assam

  18. Lahiri, Prof. Goutam Kumar

    Indian Academy of Sciences (India)

    Elected: 2005 Section: Chemistry. Lahiri, Prof. Goutam Kumar Ph.D. (Jadavpur). Date of birth: 1 January 1960. Specialization: Organometallic Chemistry and Catalysis Address: Professor, Department of Chemistry, Indian Institute of Technology, Powai, Mumbai 400 076, Maharashtra Contact: Office: (022) 2576 7159

  19. Chandrasekhar, Prof. Vadapalli

    Indian Academy of Sciences (India)

    Chandrasekhar, Prof. Vadapalli Ph.D. (IISc), FNA, FNASc, FTWAS Council Service: 2010-12. Date of birth: 6 November 1958. Specialization: Organometallic Chemistry, Inorganic Rings & Polymers and Many-Group Chemistry Address: Director, National Institute of Science Education & Research, Jatni P.O., Khordha 752 ...

  20. Chakrabarti, Prof. Bikas Kanta

    Indian Academy of Sciences (India)

    Chakrabarti, Prof. Bikas Kanta Ph.D. (Calcutta), FNA. Date of birth: 14 December 1952. Specialization: Statistical Physics, Condensed Matter Physics and Computational Physics & their Applications to Social Sciences Address: Senior Professor, Theoretical Condensed Matter Physics Divn., Saha Institute of Nuclear Physics, ...

  1. Balaji, Prof. Kithiganahalli Naranayaswamy

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2016 Section: General Biology. Balaji, Prof. Kithiganahalli Naranayaswamy Ph.D. (IISc), FNASc, FNA. Date of birth: 7 March 1966. Specialization: Immunology, Infectious Diseases Address: Department of Microbiology & Cell Biology, Indian Institute of Science, Bengaluru 560 012, Karnataka Contact:

  2. Sharma, Prof. Shobhona

    Indian Academy of Sciences (India)

    Sharma, Prof. Shobhona Ph.D. (Mumbai), FNA. Date of birth: 5 February 1953. Specialization: Molecular Parasitology, Parasite Immunology and Parasite Metabolism Address: Senior Professor & Chairperson, Department of Biological Sciences, Tata Institute of Fundamental Research, Homi Bhabha Road, Mumbai 400 005, ...

  3. Chakraborti, Prof. Asit Kumar

    Indian Academy of Sciences (India)

    Chakraborti, Prof. Asit Kumar Ph.D. (Jadavpur). Date of birth: 15 August 1954. Specialization: Synthetic Organic Chemistry, Green Chemistry, Medicinal Chemistry Address: Head, Department of Medicinal chemistry, National Institute of Pharmaceutical Education & Research, Sector 67, SAS Nagar 160 062, Panjab Contact:

  4. Patel, Prof. Bhisma Kumar

    Indian Academy of Sciences (India)

    Elected: 2018 Section: Chemistry. Patel, Prof. Bhisma Kumar Ph.D. (IIT, Kanpur), FNASc. Date of birth: 6 August 1965. Specialization: Organic Synthesis, Reaction Mechanisms, Green Chemistry Address: Department of Chemistry, Indian Institute of Technology, Guwahati 781 039, Assam Contact: Office: (0361) 258 2307

  5. Lewis, Prof. Gilbert Newton

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Lewis, Prof. Gilbert Newton. Date of birth: 25 October 1875. Date of death: 24 March 1946. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on ...

  6. Paulraj, Prof. Arogyaswami J

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2014 Honorary. Paulraj, Prof. Arogyaswami J. Date of birth: 1944. Address: Information Systems Laboratory, Stanford University, 232, David Packard EE Building, 350, Serra Mall, Stanford, CA 94305-9510, USA Contact: Email: apaulraj@stanford.edu. YouTube; Twitter; Facebook ...

  7. Zare, Prof. Richard N

    Indian Academy of Sciences (India)

    ... Refresher Courses · Symposia · Live Streaming. Home; Fellowship. Fellow Profile. Elected: 2009 Honorary. Zare, Prof. Richard N. Date of birth: 19 November 1939. Address: Department of Chemistry, Stanford University, Stanford, CA 94305-5080, USA Contact: Email: zare@stanford.edu. YouTube; Twitter; Facebook ...

  8. Imry, Prof. Yoseph

    Indian Academy of Sciences (India)

    Imry, Prof. Yoseph. Date of birth: 1939. Address: Dept of Condensed Matter Physics, The Weizmann Institute of Science, Rehovot 76100, Israel Contact: Office: (+972-8) 934 4064. Residence: (+972-8) 934 3506. Fax: (+972-8) 934 4477. Email: yoseph.imry@weizmann.ac.il. YouTube; Twitter; Facebook; Blog ...

  9. Muller, Prof. Paul Hermann

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1965 Honorary. Muller, Prof. Paul Hermann Nobel Laureate (Medicine) - 1948. Date of birth: 12 January 1899. Date of death: 13 October 1965. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  10. Sarin, Prof. Shiv Kumar

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2005 Section: Medicine. Sarin, Prof. Shiv Kumar D.M. (AIIMS), M.D. (Jaipur), FNA, FNASc, FAMS. Date of birth: 20 August 1952. Specialization: Hepatology Address: Director, Institute of Liver & Biliary Sciences, D1, Vasant Kunj, New Delhi 110 070, U.T.. Contact: Office: (011) 4630 ...

  11. Robinson, Prof. Robort

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Robinson, Prof. Robort Nobel Laureate (Chemistry) - 1947. Date of birth: 13 September 1886. Date of death: 8 February 1975. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  12. Pai, Prof. Mangalore Anantha

    Indian Academy of Sciences (India)

    Elected: 1979 Section: Engineering & Technology. Pai, Prof. Mangalore Anantha Ph.D. (UC, Berkeley), FNA, FNAE, FIEEE. Date of birth: 5 October 1931. Specialization: Smart Grid, Power Systems, Stability, Control and Computation Address: Emeritus Professor, Department of Electrical & Computer Engineering, University ...

  13. Ginzburg, Prof. Vitaly Lasazevich

    Indian Academy of Sciences (India)

    ... Refresher Courses · Symposia · Live Streaming. Home; Fellowship. Fellow Profile. Elected: 1977 Honorary. Ginzburg, Prof. Vitaly Lasazevich. Date of birth: 4 October 1916. Date of death: 8 November 2009. Last known address: Professor and Member of the Russian, Academy of Sciences, P N Lebedev Physical Institute, ...

  14. Bondi, Prof. Sir Hermann

    Indian Academy of Sciences (India)

    ... Public Lectures · Lecture Workshops · Refresher Courses · Symposia · Live Streaming. Home; Fellowship. Fellow Profile. Elected: 1997 Honorary. Bondi, Prof. Sir Hermann KCB, FRS. Date of birth: 1 November 1919. Date of death: 10 September 2005. Last known address: Fellow, Churchill College, Cambridge, CB3 0DS, ...

  15. Oda, Prof. Minoru

    Indian Academy of Sciences (India)

    Annual Meetings · Mid Year Meetings · Discussion Meetings · Public Lectures · Lecture Workshops · Refresher Courses · Symposia · Live Streaming. Home; Fellowship. Fellow Profile. Elected: 1995 Honorary. Oda, Prof. Minoru. Date of birth: 24 February 1923. Date of death: 1 March 2001. Last known address: Tokyo ...

  16. Parthasarathy, Prof. Rajagopalan

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  17. Rao, Prof. Maddali Nageswara

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  18. Pal, Prof. Arup Kumar

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  19. Mathur, Prof. Pradeep

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  20. Jain, Prof. Sanjay

    Indian Academy of Sciences (India)

    Jain, Prof. Sanjay Ph.D. (Bombay). Date of birth: 31 January 1960. Specialization: Mathematical Modelling of Complex Systems, Structure, Dynamics and Evolution of Biological & Social Networks, Theoretical Systems Biology Address: Professor, Department of Physics & Astrophysics, University of Delhi, Delhi 110 007, U.T.

  1. Saidapur, Prof. Srinivas Kishanrao

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1993 Section: Animal Sciences. Saidapur, Prof. Srinivas Kishanrao Ph.D. (Karnatak), FNA, FNASc, FTWAS. Date of birth: 7 March 1947. Specialization: Biology of Reproduction, Comparative Endocrinology, Herpetology and Animal Behaviour Address: Plot No. 108, Sripad Nagar, Saptapur, Dharwad ...

  2. Joshi, Prof. Amitabh

    Indian Academy of Sciences (India)

    Joshi, Prof. Amitabh Ph.D. (Washington State), FNASc, FNA. Date of birth: 4 March 1965. Specialization: Population & Quantitative Genetics, Evolutionary Genetics and Population Ecology Address: Professor, Evolutionary & Organismal Biology Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur P.O., ...

  3. Dharmalingam, Prof. Kuppamuthu

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1993 Section: General Biology. Dharmalingam, Prof. Kuppamuthu Ph.D. (MKU), FNASc. Date of birth: 3 January 1949. Specialization: Proteomics of Eye Diseases, Molecular Genetics, Genetic Engineering and Biotechnology Address: Director - Research, Aravind Medical Research Foundation, 1, ...

  4. Mishra, Prof. Manoj Kumar

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1999 Section: Chemistry. Mishra, Prof. Manoj Kumar Ph.D. (Florida), FNASc. Date of birth: 15 October 1952. Specialization: Electronic Structure Theory, Photo/Collisional Dynamics Address: Vice Chancellor, Birla Institute of Technology, Mesra, Ranchi 835 215, Jharkhand Contact:

  5. Balasubramanian, Prof. Sundaram

    Indian Academy of Sciences (India)

    Balasubramanian, Prof. Sundaram Ph.D. (IISc). Date of birth: 5 June 1966. Specialization: Ionic Liquids, Moulding Enzymes, Supramolecular Polymers, Molecular Simulations, Computational Chemistry Address: Chemistry & Physics of Materials Unit, JN Centre for Advanced Scientific Research, Jakkur, Bengaluru 560 064, ...

  6. Balasubramanian, Prof. Aiylam Subramania

    Indian Academy of Sciences (India)

    Balasubramanian, Prof. Aiylam Subramania Ph.D. (Kerala), FAMS. Date of birth: 15 July 1937. Specialization: Neurochemistry and Enzymology Address: 16/7A, First New Street, Thirunagar, Vellore 632 006, T.N.. Contact: Residence: (0416) 224 6260. Email: balabsu7@hotmail.com. YouTube · Twitter · Facebook · Blog ...

  7. Bhalla, Prof. Upinder Singh

    Indian Academy of Sciences (India)

    Bhalla, Prof. Upinder Singh Ph.D. (CIT), FNA. Date of birth: 21 June 1963. Specialization: Systems Biology, Computational Neuroscience and Systems Neurobiology Address: Associate Professor, National Centre for Biological Sciences, GKVK Campus, Bengaluru 560 065, Karnataka Contact: Office: (080) 2366 6130

  8. Pani, Prof. Amiya Kumar

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2012 Section: Mathematical Sciences. Pani, Prof. Amiya Kumar Ph.D. (IIT, Kanpur), FNASc. Date of birth: 3 June 1957. Specialization: Numerical Analysis, Partial Differential Equations, Industrial Mathematics Address: Chair Professor, Department of Mathematics, Indian Institute of Technology, Powai, ...

  9. Bose, Prof. Indrani

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2000 Section: Physics. Bose, Prof. Indrani Ph.D. (Calcutta), FNASc. Date of birth: 15 August 1951. Specialization: Theoretical Condensed Matter Physics, Statistical Physics, Biological Physics and Systems Biology Address: Emeritus Scientist, Department of Physics, Bose Institute, ...

  10. Balasubramanian, Prof. Kunissery Ananthasubramanian

    Indian Academy of Sciences (India)

    Elected: 2002 Section: Medicine. Balasubramanian, Prof. Kunissery Ananthasubramanian Ph.D. (Madras), FNASc, FAMS. Date of birth: 6 April 1945. Specialization: Oxidative Stress, Gastrointestinal Mucosa and Pathophysiology Address: No. 49, Guruthoppu Phase 1, II Street, Sathuvachari, Vellore 632 009, T.N.. Contact:

  11. Ramasubramanian, Prof. Sundareswaran

    Indian Academy of Sciences (India)

    Ramasubramanian, Prof. Sundareswaran Ph.D. (ISI). Date of birth: 3 March 1952. Specialization: Stochastic Processes, Stochastic Models in Insurance Address: Professor, Statistics & Mathematics Unit, Indian Statistical Institute, R.V. College P.O., Bengaluru 560 059, Karnataka Contact: Office: (080) 2848 3002-4&6/476

  12. Karman, Prof. Theodore von

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1961 Honorary. Karman, Prof. Theodore von. Date of birth: 11 May 1881. Date of death: 6 May 1963. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on the ...

  13. Cabannes, Prof. Jean

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1949 Honorary. Cabannes, Prof. Jean. Date of birth: 12 August 1885. Date of death: 31 October 1959. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on the ...

  14. Fischer, Prof. Hans

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Fischer, Prof. Hans Nobel Laureate (Chemistry) - 1930. Date of birth: 27 July 1881. Date of death: 31 March 1945. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science ...

  15. Granit, Prof. Ragnar Arthur

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1964 Honorary. Granit, Prof. Ragnar Arthur Nobel Laureate (Medicine) - 1967. Date of birth: 30 October 1900. Date of death: 11 March 1991. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  16. Cousteau, Prof. Jacques Yves

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1978 Honorary. Cousteau, Prof. Jacques Yves. Date of birth: 11 June 1910. Date of death: 25 June 1997. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on ...

  17. Millikan, Prof. Robert Andrews

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Millikan, Prof. Robert Andrews Nobel Laureate (Physics) - 1923. Date of birth: 22 March 1868. Date of death: 19 December 1953. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  18. Heisenberg, Prof. Werner Karl

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Heisenberg, Prof. Werner Karl Nobel Laureate (Physics) - 1932. Date of birth: 5 December 1901. Date of death: 1 February 1976. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  19. Niggli, Prof. Paul

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1937 Honorary. Niggli, Prof. Paul. Date of birth: 26 June 1888. Date of death: 13 January 1953. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on the teaching ...

  20. Hill, Prof. Archibald Vivian

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Hill, Prof. Archibald Vivian Nobel Laureate (Medicine) - 1922. Date of birth: 26 September 1886. Date of death: 3 June 1977. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  1. Hess, Prof. Walter Rudolf

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1966 Honorary. Hess, Prof. Walter Rudolf Nobel Laureate (Medicine) - 1949. Date of birth: 17 March 1881. Date of death: 12 August 1973. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three ...

  2. Herzberg, Prof. Gerhard

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1955 Honorary. Herzberg, Prof. Gerhard Nobel Laureate (Chemistry) - 1971. Date of birth: 25 December 1904. Date of death: 4 March 1999. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  3. Eccles, Prof. John Carew

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1968 Honorary. Eccles, Prof. John Carew Nobel Laureate (Medicine) - 1963. Date of birth: 27 January 1903. Date of death: 2 May 1997. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three ...

  4. Hadamard, Prof. Jacques

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1939 Honorary. Hadamard, Prof. Jacques. Date of birth: 8 December 1865. Date of death: 17 October 1963. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on ...

  5. Prasad, Prof. Surendra

    Indian Academy of Sciences (India)

    Prasad, Prof. Surendra Ph.D. (IIT, Delhi), FNA, FNAE, FNASc. Council Service: 2007-12. Date of birth: 10 July 1948. Specialization: Signal Processing, Communication Theory and Systems Address: Emeritus Professor, Department of Electrical Engineering, Indian Institute of Technology, Hauz Khas, New Delhi 110 016, U.T.

  6. Balaram, Prof. Padmanabhan

    Indian Academy of Sciences (India)

    Balaram, Prof. Padmanabhan Ph.D. (Carnegie Mellon), FNA, FNASc. Council Service: 1995-2000. Date of birth: 19 February 1949. Specialization: Bio-organic Chemistry and Molecular Biophysics Address: Molecular Biophysics Unit, Indian Institute of Science, Bengaluru 560 012, Karnataka Contact: Office: (080) 2293 3000

  7. Kesavan, Prof. Srinivasan

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2008 Section: Mathematical Sciences. Kesavan, Prof. Srinivasan Ph.D. (Pierre et Marie Curie), FNASc. Date of birth: 17 January 1952. Specialization: Partial Differential Equations, Homogenization and Isoperimetric Inequalities Address: 33/19, Barnaby Road, Kilpauk, Chennai 600 010, T.N.. Contact:

  8. Roy, Prof. Durga Prasad

    Indian Academy of Sciences (India)

    Roy, Prof. Durga Prasad Ph.D. (Mumbai), FNA, FNASc. Date of birth: 29 July 1941. Date of death: 17 March 2017. Specialization: Particle Physics, Astroparticle Physics Last known address: INSA Honorary Scientist, Homi Bhabha Centre for Science Education, V N Purav Marg, Mankhurd, Mumbai 400 088, Maharashtra.

  9. Ramachandran, Prof. Janakiraman

    Indian Academy of Sciences (India)

    Ramachandran, Prof. Janakiraman Ph.D. (UC, Berkeley). Date of birth: 12 June 1935. Specialization: Molecular Biology Address: Chairman, Gangagen Biotechnologies Private Limited, 12, 5th Cross, Raghavendra Layout, Tumkuar Road, Yeshwantpur, Bengaluru 560 022, Karnataka Contact: Office: (080) 4062 1300-328

  10. Datta, Prof. Asis

    Indian Academy of Sciences (India)

    Datta, Prof. Asis Ph.D and D.Sc. (Calcutta), FNA, FNASc, FTWAS. Date of birth: 2 February 1944. Specialization: Biochemistry, Molecular Biology and Genetic Engineering Address: Distinguished Scientist, National Institute of Plant Genome Research, Aruna Asaf Ali Marg, P.O. Box 10531, New Delhi 110 067, U.T.. Contact:

  11. Lorenz, Prof. Edward Norton

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1981 Honorary. Lorenz, Prof. Edward Norton. Date of birth: 23 May 1917. Date of death: 16 April 2008. Last known address: Department of Earth, Atmospheric &, Planetary Sciences, Massachusetts Institute of, Technology, Cambridge, MA 02139, U.S.A.. YouTube; Twitter; Facebook ...

  12. Liepmann, Prof. Hans Wolfgang

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1985 Honorary. Liepmann, Prof. Hans Wolfgang. Date of birth: 3 July 1914. Date of death: 24 June 2009. Last known address: Theodore von Karman Professor of, Aeronautics (Emeritus), Graduate Aeronautical Laboratories, California Institute of Technology, Pasadena, CA 91125, ...

  13. Parulkar, Prof. Gurukumar Bhalchandra

    Indian Academy of Sciences (India)

    Parulkar, Prof. Gurukumar Bhalchandra M.S. (Mumbai), FAMS. Date of birth: 1 December 1931. Specialization: Open Heart Surgery, Extracorporeal Circulation, Coronary Bypass Surgery and Vascular Surgery Address: Flat No. 31, Building 4, Haji Ali Government Colony, K K Marg, Mumbai 400 034, Maharashtra Contact:

  14. Mondal, Prof. Naba Kumar

    Indian Academy of Sciences (India)

    Mondal, Prof. Naba Kumar Ph.D. (Bombay) D.Sc. (h.c.), FNA, FNASc, FTWAS. Date of birth: 11 March 1951. Specialization: Experimental Particle Physics, Accelerator-based Particle Physics and Neutrino Physics Address: Raja Ramanna Fellow, Saha Institute of Nuclear Physics, 1/AF, Bidhan Nagar, Kolkata 700 064, W.B.

  15. Chakraborty, Prof. Ranajit

    Indian Academy of Sciences (India)

    Elected: 2006 Honorary. Chakraborty, Prof. Ranajit. Date of birth: 1946. Address: Director, Center for Computational Genomics, University of North Texas, HSC, 3500 Camp Bowie Blvd, CBH 249, Fort Worth, TX 76107, U.S.A.. Contact: Office: (+1-817) 735 2421. Fax: (+1-817) 735 5016. Email: ranajit.chakraborty@unthsc.

  16. Bahadur, Prof. Raghu Raj

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1975 Section: Mathematical Sciences. Bahadur, Prof. Raghu Raj Ph.D. (North Carolina), FNA. Date of birth: 30 April 1924. Date of death: 7 June 1997. Specialization: Mathematical Statistics Address: No.9, Raj Narain Road, Apartment 4A, Civil Lines, Delhi 110 054. YouTube; Twitter; Facebook; Blog ...

  17. Kahn, Prof. Oliver

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1999 Honorary. Kahn, Prof. Oliver. Date of birth: 13 September 1942. Date of death: 8 December 1999. Last known address: Laboratoire des Sciences Moléculair, Institut de Chimie de la Matire, Condensée de Bordeaux, UPR CNRS No. 9048, 33608 Pessac, France. YouTube; Twitter; Facebook ...

  18. Rao, Prof. Valipe Ramgopal

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2009 Section: Engineering & Technology. Rao, Prof. Valipe Ramgopal FNAE, FNASc, FNA, FIEEE. Date of birth: 16 August 1965. Specialization: Nanoelectronics and Nanotechnology Address: Director, Indian Institute of Technology, Hauz Khas, New Delhi 110 016, U.T.. Contact:

  19. Houssay, Prof. Bernardo Alberto

    Indian Academy of Sciences (India)

    SPEAKER: Prof. Krishnaswamy Ravi-Chandar. VENUE: Faculty Hall, Indian Institute of Science. 23 February 2018 ǀ 1500. Event poster · Introducing: Summer Schools. Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and ...

  20. Born, Prof. Max

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1937 Honorary. Born, Prof. Max Nobel Laureate (Physics) - 1954. Date of birth: 11 December 1882. Date of death: 5 January 1970. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science ...

  1. Compton, Prof. Arthur Holly

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Compton, Prof. Arthur Holly Nobel Laureate (Physics) - 1927. Date of birth: 10 September 1892. Date of death: 15 March 1962. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  2. Salam, Prof. Abdus

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1988 Honorary. Salam, Prof. Abdus Nobel Laureate (Physics) - 1979. Date of birth: 29 January 1926. Date of death: 21 November 1996. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three ...

  3. Leiper, Prof. Robert Thomson

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1938 Honorary. Leiper, Prof. Robert Thomson. Date of birth: 17 April 1881. Date of death: 21 May 1969. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on the ...

  4. Bowen, Prof. Norman Levi

    Indian Academy of Sciences (India)

    SPEAKER: Prof. Krishnaswamy Ravi-Chandar. VENUE: Faculty Hall, Indian Institute of Science. 23 February 2018 ǀ 1500. Event poster · Introducing: Summer Schools. Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and ...

  5. Anderson, Prof. John Stuart

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1978 Honorary. Anderson, Prof. John Stuart. Date of birth: 9 January 1908. Date of death: 25 December 1990. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India ...

  6. Ruzicka, Prof. Leopold Stephen

    Indian Academy of Sciences (India)

    SPEAKER: Prof. Krishnaswamy Ravi-Chandar. VENUE: Faculty Hall, Indian Institute of Science. 23 February 2018 ǀ 1500. Event poster · Introducing: Summer Schools. Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and ...

  7. Halle, Prof. Thore Gustaf.

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1947 Honorary. Halle, Prof. Thore Gustaf. Date of birth: 25 September 1884. Date of death: 12 May 1964. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on ...

  8. Engstrom, Prof. Arne Vilhelm

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1970 Honorary. Engstrom, Prof. Arne Vilhelm. Date of birth: 15 May 1920. Date of death: 19 July 1996. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on the ...

  9. Hodgkin, Prof. Dorothy Crowfoot

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1972 Honorary. Hodgkin, Prof. Dorothy Crowfoot Nobel Laureate (Chemistry) - 1964. Date of birth: 12 May 1910. Date of death: 29 July 1994. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  10. Mulliken, Prof. Robert Sanderson

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1969 Honorary. Mulliken, Prof. Robert Sanderson Nobel Laureate (Chemistry) - 1966. Date of birth: 7 June 1896. Date of death: 31 October 1986. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  11. Charney, Prof. Jule Gregory

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1980 Honorary. Charney, Prof. Jule Gregory. Date of birth: 1 January 1917. Date of death: 16 June 1981. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on ...

  12. Hahn, Prof. Otto

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1958 Honorary. Hahn, Prof. Otto Nobel Laureate (Chemistry) - 1944. Date of birth: 8 March 1879. Date of death: 28 July 1968. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science ...

  13. Medawar, Prof. Peter Brian

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1968 Honorary. Medawar, Prof. Peter Brian Nobel Laureate (Medicine) - 1960. Date of birth: 28 February 1915. Date of death: 2 October 1987. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  14. Seward, Prof. Albert Charles

    Indian Academy of Sciences (India)

    SPEAKER: Prof. Krishnaswamy Ravi-Chandar. VENUE: Faculty Hall, Indian Institute of Science. 23 February 2018 ǀ 1500. Event poster · Introducing: Summer Schools. Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and ...

  15. Cotton, Prof. Aime Auguste

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Cotton, Prof. Aime Auguste. Date of birth: 9 October 1869. Date of death: 16 April 1951. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on the ...

  16. Minwalla, Prof. Shiraz

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2011 Section: Physics. Minwalla, Prof. Shiraz Ph.D. (Princeton). Date of birth: 2 January 1972. Specialization: String Theory, Gravity, Quantum Field Theory Address: Department of Theoretical Physics, Tata Institute of Fundamental Research, Homi Bhabha Road, Mumbai 400 005, ...

  17. Pandian, Prof. Thavamani Jegajothivel

    Indian Academy of Sciences (India)

    Elected: 1985 Section: Animal Sciences. Pandian, Prof. Thavamani Jegajothivel Ph.D. (Madras), Dr. rer. nat. (Kiel, Germany), FNA, FNASc, FNAAS, FTWAS, D.Sc. (CIFE, Mumbai). Date of birth: 15 June 1939. Specialization: Genetics and Energetics: Aquaculture Address: 9, Old Natham Road, Opp. Balamandiram, Madurai ...

  18. Rao, Prof. Basuthkar Jagadeeshwar

    Indian Academy of Sciences (India)

    Rao, Prof. Basuthkar Jagadeeshwar Ph.D. (IISc), FNASc, FNA. Date of birth: 13 March 1956. Specialization: Genome Dynamics, Biology of Cellular Adaptations, Computational Biology Address: Department of Biological Sciences, Tata Institute of Fundamental Research, Homi Bhabha Road, Mumbai 400 005, Maharashtra

  19. Haritsa, Prof. Jayant Ramaswamy

    Indian Academy of Sciences (India)

    Elected: 2011 Section: Engineering & Technology. Haritsa, Prof. Jayant Ramaswamy Ph.D. (Wisconsin), FNAE, FNASc, FIEEE. Date of birth: 10 March 1964. Specialization: Database Systems Address: FACM Professor, Dept. of Computational & Data Sciences, Indian Institute of Science, Bengaluru 560 012, Karnataka

  20. Chandru, Prof. Vijay

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1996 Section: Engineering & Technology. Chandru, Prof. Vijay Ph.D. (MIT). Date of birth: 7 June 1953. Specialization: Data Science, Computational Mathematics and Computational Biology Address: Chairman, Strand Life Sciences, 591, III Main Road, Sadashivanagar, Bengaluru 560 080, Karnataka

  1. Caspersson, Prof. Torbjorn Oskar

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1963 Honorary. Caspersson, Prof. Torbjorn Oskar. Date of birth: 15 October 1910. Date of death: 7 December 1997. Last known address: Professor, Department of Tumor Pathology, Karolinska Sjukhuset, S-104 01 Stockholm 60, Sweden. YouTube; Twitter; Facebook; Blog ...

  2. Gandhi, Prof. Kandukuri Sivananda

    Indian Academy of Sciences (India)

    Elected: 1990 Section: Engineering & Technology. Gandhi, Prof. Kandukuri Sivananda Ph.D. (UC, Berkeley). Date of birth: 23 December 1942. Specialization: Batteries and Fuel Cells, Multiphase Fluid Systems and Polymer Reaction Engineering Address: Department of Chemical Engineering, Indian Institute of Science, ...

  3. Rao, Prof. Palle Rama

    Indian Academy of Sciences (India)

    Rao, Prof. Palle Rama Ph.D. (Banaras), F.Eng. (UK), FNA, FNASc, FNAE, FASM, FTWAS, Foreign Member - US Natl. Acad. Engg. Council Service: 1989-2000; Vice-President: 1992-94; President: 1995-97. Date of birth: 30 June 1937. Specialization: Deformation, Fracture and Materials Development Address: Chairman ...

  4. Rao, Prof. Aroor Pramesh

    Indian Academy of Sciences (India)

    Rao, Prof. Aroor Pramesh Ph.D. (Mumbai). Date of birth: 18 January 1948. Specialization: Sun & Solar Wind, Wave Propagation in Random Media, Aperture Synthesis and Radio Imaging Address: Flat 7, Khagol Housing Society, Panchavati, Pashan, Pune 411 008, Maharashtra Contact: Residence: (020) 6628 0183

  5. Rao, Prof. Kalya Jagannatha

    Indian Academy of Sciences (India)

    Rao, Prof. Kalya Jagannatha Ph.D. (IIT, Kanpur), D.Sc. (IISc), FNA, FNASc, D.Sc. (h.c., Univ. Bordeaux, France) Council Service: 1998-2003. Date of birth: 7 December 1940. Specialization: Amorphous Solids & Ceramics and Phase Transitions Address: 187/1, Tadvanam Estate, Halasinganahalli Road, Kalya Post, Magadi ...

  6. Rao, Prof. Arikkala Raghurama

    Indian Academy of Sciences (India)

    Elected: 2012 Section: Physics. Rao, Prof. Arikkala Raghurama Ph.D. (Mumbai). Date of birth: 14 June 1954. Specialization: X-ray Astronomy, X-ray Instrumentation, High Energy Astrophysics Address: Department of Astronomy & Astrophysics, Tata Institute of Fundamental Research, Homi Bhabha Road, Mumbai 400 005, ...

  7. Rao, Prof. Calyampudi Radhakrishna

    Indian Academy of Sciences (India)

    Date of birth: 10 September 1920. Specialization: Statistics with Applications to Biology, Signal Processing and Pattern Recognition Address: Distinguished Professor Emeritus, CR Rao Advanced Institute, University of Hyderabad Campus, Prof. CR Rao Road, Hyderabad 500 046, A.P.. Contact: Office: (040) 2313 1170

  8. Rao, Prof. Chebrolu Pulla

    Indian Academy of Sciences (India)

    Rao, Prof. Chebrolu Pulla Ph.D. (IISc), FNASc, FNA. Date of birth: 13 May 1954. Specialization: Bioinorganic Chemistry, Supramolecular Chemistry, Ion & Molecular Receptors, Metalloproteins & Metalloenzymes Address: Institute Chair Professor, Department of Chemistry, Indian Institute of Technology, Powai, Mumbai 400 ...

  9. Bhattacharjee, Prof. Jayanta Kumar

    Indian Academy of Sciences (India)

    Bhattacharjee, Prof. Jayanta Kumar Ph.D. (Maryland), FNASc. Date of birth: 10 April 1952. Specialization: Critical Phenomena, Turbulence and Nonlinear Dynamics Address: Distinguished Emeritus Fellow, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700 032, W.B.. Contact: Residence: 98307 47103

  10. Tandon, Prof. Prakash Narain

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1983 Section: Medicine. Tandon, Prof. Prakash Narain M.B.B.S. (Lucknow), M.S., D.Sc. (h.c.), FRCS, FNA, FNASc, FTWAS, FAMS. Date of birth: 13 August 1928. Specialization: Neurosciences and Neurosurgery Address: No. 1, Jagriti Enclave, Vikas Marg Extension, Delhi 110 092, ...

  11. Bera, Prof. Jitendra Kumar

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2014 Section: Chemistry. Bera, Prof. Jitendra Kumar Ph.D. (IISc). Date of birth: 24 October 1968. Specialization: Organometallic Chemistry, Small Molecule Activation, Catalysis Address: Department of Chemistry, Indian Institute of Technology, Kanpur 208 016, U.P.. Contact: Office: ...

  12. Schmidt, Prof. Brian P

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2014 Honorary. Schmidt, Prof. Brian P Nobel Laureate (Physics), FRS. Date of birth: 24 February 1967. Address: Vice Chancellor, The Australian National University, via Cotter Road, Weston Creek, ACT 2611, Australia Contact: Office: (+61-2) 6125 2510. Fax: (+61-2) 6125 0260

  13. Yadav, Prof. Veejendra Kumar

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2007 Section: Chemistry. Yadav, Prof. Veejendra Kumar Ph.D. (Baroda). Date of birth: 13 June 1956. Specialization: Synthetic Organic Chemistry and Physical Organic Chemistry Address: Professor, Department of Chemistry, Indian Institute of Technology, Kanpur 208 016, U.P.

  14. Sarkar, Prof. Debi Prasad

    Indian Academy of Sciences (India)

    Sarkar, Prof. Debi Prasad Ph.D. (Calcutta), FNASc, FNA. Date of birth: 15 January 1958. Specialization: Membrane Biology, Biochemistry, Molecular Virology, Cell Biology and Biotechnology Address: Director, Indian Institute of Science Education & Research, Sector 81, Manuli, SAS Nagar 140 306, Chandigarh Contact:

  15. Rao, Prof. Kaza Kesava

    Indian Academy of Sciences (India)

    Elected: 1992 Section: Engineering & Technology. Rao, Prof. Kaza Kesava Ph.D. (Houston). Date of birth: 12 April 1956. Specialization: Flow of Granular Materials and Defluoridation of Drinking Water Address: Professor, Department of Chemical Engineering, Indian Institute of Science, Bengaluru 560 012, Karnataka

  16. Semenov, Prof. Nikolai Nikolaevich

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1960 Honorary. Semenov, Prof. Nikolai Nikolaevich Nobel Laureate (Chemistry) - 1956. Date of birth: 16 April 1896. Date of death: 26 September 1986. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement ...

  17. Garrett, Prof. Stephen Denis

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1973 Honorary. Garrett, Prof. Stephen Denis. Date of birth: 1 November 1906. Date of death: 26 December 1989. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of ...

  18. Cheetham, Prof. Antony Kevin

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2001 Honorary. Cheetham, Prof. Antony Kevin FRS. Date of birth: 16 November 1946. Address: Dept. of Materials Science &, Metallurgy, University of Cambridge, 27, Charles Babbage Road, Cambridge CB3 0FS, uk. Contact: Office: (+44-1223) 74 6733. Fax: (+44-1223) 33 4567

  19. Dighe, Prof. Rajan Ramakant

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2010 Section: Animal Sciences. Dighe, Prof. Rajan Ramakant Ph.D. (IISc), FNASc, FNA. Date of birth: 21 March 1951. Specialization: Molecular Endocrinology, Reproductive Biology, Biochemistry Address: Molecular Reproduction & Developmental Genetics, Indian Institute of Science, Bengaluru 560 ...

  20. Kant, Prof. Tarun

    Indian Academy of Sciences (India)

    Kant, Prof. Tarun Ph.D. (IIT, Bombay), FNA, FNAE, FNASc. Date of birth: 1 July 1946. Specialization: Solid & Structural Mechanics, Finite Element Methods and Mechanics of Composite Materials & Structures Address: Professor Emeritus &INSA Senior Scientist, Department of Civil Engineering, Indian Institute of Technology, ...

  1. Kant, Prof. Rama

    Indian Academy of Sciences (India)

    Elected: 2015 Section: Chemistry. Kant, Prof. Rama Ph.D. (IISc). Date of birth: 18 January 1963. Specialization: Complex Systems in Electrochemistry & Polymers, Theoretical Chemistry, Nanoelectrochemistry Address: Department of Chemistry, University of Delhi, Delhi 110 007, U.T.. Contact: Office: (011) 2766 6646/188

  2. Das, Prof. Prasanta Kumar

    Indian Academy of Sciences (India)

    Elected: 2017 Section: Chemistry. Das, Prof. Prasanta Kumar Ph.D. (Osmania). Date of birth: 2 June 1971. Specialization: Bio-organic Chemistry, Supramolecular Self Assemblies, Enzymology, Soft Nanocomposite in Cellular Transportation Address: Department of Biological Chemistry, Indian Association for the Cultivation ...

  3. Khorana, Prof. Har Gobind

    Indian Academy of Sciences (India)

    Elected: 1976 Honorary. Khorana, Prof. Har Gobind Nobel Laureate (Medicine) - 1968. Date of birth: 9 January 1922. Date of death: 9 November 2011. Last known address: Alfred P. Sloan Professor of, Biology and Chemistry, Massachusetts Institute of, Technology, 77 Massachusetts Ave., Cambridge, MA 02139, U.S.A..

  4. Kamal, Prof. Aditya Kumar

    Indian Academy of Sciences (India)

    Elected: 1974 Section: Engineering & Technology. Kamal, Prof. Aditya Kumar Dr. lng. (Paris). Date of birth: 5 July 1927. Specialization: Air Traffic Control, Surveillance, Automation, UAV, GPS, Cyber Security Address: 18, Crystal Circle, Burlington, MA 01803, USA Contact: Office: (+1-781) 890 3330/235. Residence: (+1-781) ...

  5. Dhavale, Prof. Dilip Dattatray

    Indian Academy of Sciences (India)

    Elected: 2009 Section: Chemistry. Dhavale, Prof. Dilip Dattatray Ph.D. (Pune), FNASc. Date of birth: 18 February 1956. Specialization: Natural Products Chemistry, Carbohydrate Chemistry, Photochemistry, Reaction Mechanism, Medicinal Chemistry Address: Department of Chemistry, University of Pune, Pune 411 007, ...

  6. Kaliappan, Prof. Krishna Pillai

    Indian Academy of Sciences (India)

    Elected: 2016 Section: Chemistry. Kaliappan, Prof. Krishna Pillai Ph.D. (IISc). Date of birth: 16 March 1968. Specialization: Organic Synthesis, Medicinal Chemistry, Natural Products Address: Department of Chemistry, Indian Institute of Technology, Powai, Mumbai 400 076, Maharashtra Contact: Office: (022) 2576 7177

  7. Dasgupta, Prof. Pallab

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2015 Section: Engineering & Technology. Dasgupta, Prof. Pallab Ph.D. (IIT, Kharagpur), FNAE. Date of birth: 31 October 1967. Specialization: Electronic Design Automation, Artificial Intelligence, Formal Methods Address: Department of Computer Science & Engineering, Indian Institute of Technology ...

  8. Chakrabarti, Prof. Partha Pratim

    Indian Academy of Sciences (India)

    Elected: 2000 Section: Engineering & Technology. Chakrabarti, Prof. Partha Pratim Ph.D. (IIT, Kharagpur), FNA, FNAE. Date of birth: 1 October 1962. Specialization: Artificial Intelligence, Computer Aided Design for VLSI and Algorithms Address: Director, Indian Institute of Technology, Kharagpur 721 302, W.B.. Contact:

  9. Chhuttani, Prof. Pran Nath

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1975 Section: Medicine. Chhuttani, Prof. Pran Nath M.D., D.Sc. (h.c.). Date of birth: 26 February 1915. Date of death: 19 July 1996. Specialization: Gastroenterology and Internal Medicine Address: House No. 22, Sector 4, Chandigarh 160 001. YouTube · Twitter · Facebook · Blog ...

  10. Ramamritham, Prof. Krithivasan

    Indian Academy of Sciences (India)

    Elected: 2010 Section: Engineering & Technology. Ramamritham, Prof. Krithivasan Ph.D. (Utah), FNAE, FIEEE, FNASc. Date of birth: 28 February 1955. Specialization: Databases, Real-Time Systems, Use of Information & Communication Technology for Socioeconomic Development Address: Department of Computer ...

  11. Pitke, Prof. Madhukar Vishwanath

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1986 Section: Engineering & Technology. Pitke, Prof. Madhukar Vishwanath Ph.D. (Mumbai), FIEEE. Date of birth: 31 March 1936. Specialization: Electronics, Telecommunication & Information Technology, Technology Transfer and Wireless Communication Address: 002, Buniyad, Yashodham A2-15 ...

  12. Paul, Prof. Vinod Kumar

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2016 Section: Medicine. Paul, Prof. Vinod Kumar Ph.D. (AIIMS), FAMS, FNASc. Date of birth: 1 August 1955. Specialization: Paediatrics, Newborn Health Address: Department of Paediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, U.T.. Contact:

  13. Vijayraghavan, Prof. Usha

    Indian Academy of Sciences (India)

    Vijayraghavan, Prof. Usha Ph.D. (Caltech), FNA. Date of birth: 25 August 1961. Specialization: Plant Developmental Genetics, Microbial Genetics and Gene Regulation Address: Professor, Microbiology & Cell Biology Department, Indian Institute of Science, Bengaluru 560 012, Karnataka Contact: Office: (080) 2360 0168

  14. Mittal, Prof. Sanjay

    Indian Academy of Sciences (India)

    Mittal, Prof. Sanjay Ph.D. (Minnesota), FNAE, FNA, FNASc. Date of birth: 27 February 1968. Specialization: Unsteady Aerodynamics, Finite Element Analysis, High Performance Computing and Bluff-body Flows, Aerodynamic Shape Optimization Address: Department of Aerospace Engineering, Indian Institute of Technology, ...

  15. Padmanaban, Prof. Govindarajan

    Indian Academy of Sciences (India)

    Padmanaban, Prof. Govindarajan Ph.D. (IISc), FNA, FNASc, FTWAS Council Service: 1986-88, 1992-97; Vice-President: 1992-97. Date of birth: 20 March 1938. Specialization: Molecular Biology, Recombinant DNA and Malarial Parasite Address: NASI Senior Scientist, Department of Biochemistry, Indian Institute of Science, ...

  16. Gopalan, Prof. Kunchithapadam

    Indian Academy of Sciences (India)

    Elected: 1983 Section: Earth & Planetary Sciences. Gopalan, Prof. Kunchithapadam Ph.D. (IISc), FNA, FNASc. Date of birth: 12 August 1938. Specialization: Geo-& Cosmo-Chronology, Isotope Geology and Mass Spectrometry Address: 38765, Adcock Drive, Fremont, CA 94536, USA Contact: Residence: (+1-510) 386 4484

  17. Chaturvedi, Prof. Umesh Chandra

    Indian Academy of Sciences (India)

    Chaturvedi, Prof. Umesh Chandra M.D. (Lucknow), FRC Path. (London), FAMS, FNA, FNASc, FAAM(USA). Date of birth: 2 March 1939. Specialization: Medical Microbiology, Virology and Immunology Address: 201, Annapurna Apartments, No. 1, Bishop Rocky Street, Faizabad Road, Lucknow 226 007, U.P.. Contact:

  18. Rao, Prof. Addicam Jagannadha

    Indian Academy of Sciences (India)

    Rao, Prof. Addicam Jagannadha Ph.D. (IISc), FNA, FNASc, FAMS. Date of birth: 11 July 1942. Specialization: Regulation of Placental Function, Cellular Differentiation, Primate Biology, Oocyte Maturation Address: INSA Senior Scientist, Department of Biochemistry, Indian Institute of Science, Bengaluru 560 012, Karnataka

  19. Madhusudana, Prof. Nelamangala Vedavyasachar

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1974 Section: Physics. Madhusudana, Prof. Nelamangala Vedavyasachar Ph.D. (Mysore), FNA. Date of birth: 9 May 1944. Specialization: Liquid Crystals Address: INSA Senior Scientist, Liquid Crystal Laboratory, Raman Research Institute, CV Raman Avenue, Bengaluru 560 080, Karnataka Contact:

  20. Bhattacharya, Prof. Samaresh

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2006 Section: Chemistry. Bhattacharya, Prof. Samaresh Ph.D. (Jadavpur). Date of birth: 24 August 1960. Specialization: Co-ordination Chemistry and Organometallic Chemistry Address: Professor, Inorganic Chemistry Section, Department of Chemistry, Jadavpur University, Kolkata 700 032, W.B.

  1. Sengupta, Prof. Pulak

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2011 Section: Earth & Planetary Sciences. Sengupta, Prof. Pulak Ph.D. (Jadavpur), FNA. Date of birth: 5 December 1963. Specialization: Precambrian Geology, Metamorphic Petrology Address: Department of Geological Sciences, Jadavpur University, Kolkata 700 032, W.B.

  2. Indrayan, Prof. Abhaya

    Indian Academy of Sciences (India)

    Elected: 2010 Section: Medicine. Indrayan, Prof. Abhaya Ph.D. (Ohio State), FAMS. Date of birth: 11 November 1945. Specialization: Medical Biostatistics, Medical Research Methodology, Medical Informatics Address: A 037, Telecom City, B 9/6, Sector 62, Noida 201 309, U.P.. Contact: Residence: (0120) 240 0396

  3. Yegnanarayana, Prof. Bayya

    Indian Academy of Sciences (India)

    Elected: 2004 Section: Engineering & Technology. Yegnanarayana, Prof. Bayya Ph.D. (IISc), FNA, FNAE, FIEEE. Date of birth: 9 January 1944. Specialization: Signal Processing, Speech & Vision and Artificial Neural Networks Address: Professor, International Institute of Information Technology, Gachi Bowli, Hyderabad 500 ...

  4. Shenoy, Prof. Vijay Balakrishna

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  5. Bhattacharya, Prof. Sourendra Kumar

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1994 Section: Earth & Planetary Sciences. Bhattacharya, Prof. Sourendra Kumar Ph.D. (Gujarat), FNASc. Date of birth: 4 January 1948. Specialization: Isotope Geochemistry and Anomalous Isotope Fractionation Address: 406, Shri Raj Apartments, Vastrapur, Ahmedabad 380 015, Gujarat Contact:

  6. Nocera, Prof. Daniel G

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2013 Honorary. Nocera, Prof. Daniel G. Date of birth: 1957. Address: Dept. of Chemistry & Chem. Biol., Harvard University, 12, Oxford Street, Cambridge, MA 02138, USA Contact: Office: (+1-617) 495 8904. Email: dnocera@fas.harvard.edu. http://chemistry.harvard.edu/people/daniel-g-nocera.

  7. Livage, Prof. Jacques

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2004 Honorary. Livage, Prof. Jacques. Date of birth: 26 October 1938. Address: Chemie de la Matiere Condensee, UPMC, Tour 44, 4, Place Jussieu, 75005 Paris, France Contact: Office: (+33-1) 4427 6162. Residence: (+33-6) 6797 6839. Fax: (+33-1) 4427 4769

  8. Ashtekar, Prof. Abhay

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1996 Honorary. Ashtekar, Prof. Abhay. Date of birth: 5 July 1949. Address: Director, Inst. for Gravitation and, the Cosmos, Pennsylvania State University, University Park, PA 16802-6300, U.S.A.. Contact: Office: (+1-814) 863 9605. Residence: (+1-814) 867 8406. Fax: (+1-814) 863 ...

  9. Fisher, Prof. Michael Ellis

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2001 Honorary. Fisher, Prof. Michael Ellis FRS. Date of birth: 3 September 1931. Address: Distinguished Professor Emeritus, Institute of Physical Science and, Technology, University of Maryland, College Park, MD 20742-2431, U.S.A.. Contact: Office: (+1-301) 405 4819

  10. Roesky, Prof. Herbert Walter

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1997 Honorary. Roesky, Prof. Herbert Walter. Date of birth: 6 November 1935. Address: Director, Institut füer Anorganische Chemie, der Universität Göettingen, Tammannstrasse 4, D-37077 Göttingen, Germany Contact: Office: (+49-551) 393 0001. Residence: (+49-551) 76 183

  11. Anil Kumar, Prof.

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1987 Section: Chemistry. Anil Kumar, Prof. Ph.D. (IIT Kanpur), FNA, FNASc, FTWAS. Date of birth: 25 June 1941. Specialization: Nuclear Magnetic Resonance Spectroscopy, NMR ... Office: (080) 2293 2724. Residence: (080) 2366 2757. Mobile: 98454 21938. Fax: (080) 2360 1550

  12. Bhattacharyya, Prof. Archana

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2007 Section: Earth & Planetary Sciences. Bhattacharyya, Prof. Archana Ph.D. (Northwestern), FNASc, FNA. Date of birth: 1 June 1948. Specialization: Ionospheric Physics ... Office: (022) 2748 4147. Residence: (022) 2772 2014. Mobile: 96195 43004. Fax: (022) 2748 0762

  13. Das, Prof. Amita

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2011 Section: Physics. Das, Prof. Amita Ph.D. (IIT, Kanpur). Date of birth: 3 August 1965. Specialization: Strongly Coupled & Dusty Plasma Systems, Laser Plasma Interactions, Plasma Physics, Turbulence, Electron Magnetohydrodynamics Address: ... Office: (079) 2396 2078

  14. Griffiths, Prof. Phillip

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2004 Honorary. Griffiths, Prof. Phillip. Date of birth: 19 October 1938. Address: Director Emeritus Professor of, Mathematics, Institute for Advanced Study, No. 1, Einstein Drive, Princeton, NJ 08540, U.S.A.. Contact: Office: (+1-609)734 8041. Residence: (+1-410) 810 3103

  15. Anand, Prof. Gargeshwari Venkatasubbiah

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1997 Section: Engineering & Technology. Anand, Prof. Gargeshwari Venkatasubbiah Ph.D. (IISc), FNAE. Date of birth: 16 October 1943. Specialization: Statistical Signal ... III Stage, Bengaluru 560 085, Karnataka Contact: Office: (080) 2672 1983/838. Residence: (080) 2361 1263

  16. Veluthambi, Prof. Karuppanna

    Indian Academy of Sciences (India)

    Veluthambi, Prof. Karuppanna Ph.D. (IISc), FNA, FNASc. Date of birth: 7 March 1953. Specialization: Plant Genetic Engineering, Plant Biotechnology and Plant Molecular Biology Address: INSA Senior Scientist, Department of Plant Biotechnology, School of Biotechnology, Madurai Kamaraj University, Madurai 625 021, T.N.

  17. Tyagi, Prof. Jaya Sivaswami

    Indian Academy of Sciences (India)

    Elected: 2008 Section: Medicine. Tyagi, Prof. Jaya Sivaswami Ph.D. (Delhi), FNASc, FNA. Date of birth: 19 May 1954. Specialization: Molecular Biology, Mycobacteriology and Gene Regulation Address: Head, Department of Biotechnology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, U.T.

  18. Raman, Prof. Rajiva

    Indian Academy of Sciences (India)

    Elected: 1996 Section: Animal Sciences. Raman, Prof. Rajiva Ph.D. (Banaras), FNA, FNASc. Date of birth: 9 December 1948. Specialization: Human Molecular Genetics & Cytogenetics, Gene Expression & Chromatin Organization in Development and Sex Determination Address: Professor Emeritus, Department of Zoology, ...

  19. Lakshmanan, Prof. Muthusamy

    Indian Academy of Sciences (India)

    Elected: 1991 Section: Physics. Lakshmanan, Prof. Muthusamy Ph.D. (Madras), FNA, FNASc, FTWAS Council Service: 2010-12. Date of birth: 25 March 1946. Specialization: Nonlinear Dynamics, Theoretical Physics and Mathematical Physics Address: DST SERB Distinguished Fellow, Centre for Nonlinear Dynamics and, ...

  20. Mehta, Prof. Chandra Lal

    Indian Academy of Sciences (India)

    Elected: 1982 Section: Physics. Mehta, Prof. Chandra Lal Ph.D. (Rochester). Date of birth: 31 July 1938. Specialization: Quantum & Statistical Optics and Mathematical Physics Address: B-43, Gyandeep Apartments, Mayur Vihar, Phase I, New Delhi 110 091, U.T.. Contact: Residence: (011) 2279 6410. Mobile: 90133 91375

  1. Das, Prof. Saumitra

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2009 Section: General Biology. Das, Prof. Saumitra Ph.D. (Calcutta), FNASc, FNA. Date of birth: 20 January 1962. Specialization: Molecular Virology, Molecular Biology and Cell Biology Address: Microbiology and Cell Biology Department, Indian Institute of Science, Bengaluru 560 012, Karnataka

  2. Vijay Kumar, Prof. Panganamala

    Indian Academy of Sciences (India)

    Elected: 2017 Section: Engineering & Technology. Vijay Kumar, Prof. Panganamala Ph.D. (Southern Calif.), FNAE, FNA, FIEEE. Date of birth: 22 September 1955. Specialization: Codes for Distributed Storage, Error Correcting Codes, Wireless Communication Address: Department of Electrical Communication Engineering, ...

  3. Meyer, Prof. Kurt H.

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1952 Honorary. Meyer, Prof. Kurt H. Date of birth: 29 September 1883. Date of death: 14 April 1952. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on the ...

  4. Bhattacherjee, Prof. Satyendra Kumar

    Indian Academy of Sciences (India)

    Bhattacherjee, Prof. Satyendra Kumar Ph.D. (Notre Dame). Date of birth: 2 October 1926. Date of death: 28 April 2013. Specialization: Experimental Nuclear Physics Last known address: 302B, Tribute, Rajkamal Studio Compound, Off Dr SS Rao Road, Behind Mahatma Gandhi Memorial Hospital, Parel, Mumbai 400 012.

  5. Ahluwalia, Prof. Jagdish Chander

    Indian Academy of Sciences (India)

    Ahluwalia, Prof. Jagdish Chander Ph.D. (Purdue), FNA. Date of birth: 6 July 1935. Specialization: Thermodynamics of Biopolymers & Surfactants in Solutions and Solute-Solvent Interactions Address: 186, SFS Apartments, Hauz Khas, New Delhi 110 016, U.T.. Contact: Residence: (011) 2656 4519. Mobile: 92137 36359

  6. Datta, Prof. Swapan Kumar

    Indian Academy of Sciences (India)

    Datta, Prof. Swapan Kumar Ph.D. (Calcutta), FNA, FNASc, FNAAS, FTWAS. Date of birth: 28 January 1953. Specialization: Plant Biotechnology, Genetic Engineering, Crop Improvement Address: Vice Chancellor, Visva Bharati University, Santiniketan 731 235, W.B.. Contact: Office: (03463) 26 2451. Mobile: 87686 44777

  7. Agrawal, Prof. Manindra

    Indian Academy of Sciences (India)

    Elected: 2004 Section: Engineering & Technology. Agrawal, Prof. Manindra Ph.D. (IIT, Kanpur), FNAE, FNA, FNASc, FTWAS Council Service: 2016-. Date of birth: 20 May 1966. Specialization: Computational Complexity Theory and Computation Number Theory Address: Professor, Department of Computer Science, Indian ...

  8. Goodenough, Prof. John B

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1980 Honorary. Goodenough, Prof. John B. Date of birth: 25 July 1922. Address: Virginia H Cockrell Centennial, Professor of Engineering, University of Texat at Austin, ETC 9.184, Stop C2200, Austin, TX 78712, U.S.A.. Contact: Office: (+1-512) 471 1646. Email: jgoodenough@mail.utexas.edu.

  9. Arakeri, Prof. Vijay Hanumappa

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1991 Section: Engineering & Technology. Arakeri, Prof. Vijay Hanumappa Ph.D. (Caltech). Date of birth: 9 August 1945. Specialization: Cavitation, Hydrodynamics and Two-phase Flows Address: Department of Mechanical Engineering, Indian Institute of Science, Bengaluru 560 012, Karnataka

  10. Mitochondrial Tim9 protects Tim10 from degradation by the protease Yme1.

    Science.gov (United States)

    Spiller, Michael P; Guo, Liang; Wang, Qi; Tran, Peter; Lu, Hui

    2015-03-17

    Translocase of IM (inner membrane; Tim)9 and Tim10 are essential homologue proteins of the mitochondrial intermembrane space (IMS) and form a stable hexameric Tim9-Tim10 complex there. Redox-switch of the four conserved cysteine residues plays a key role during the biogenesis of these proteins and, in turn, the Tim proteins play a vital chaperone-like role during import of mitochondrial membrane proteins. However, the functional mechanism of the small Tim chaperones is far from solved and it is unclear whether the individual proteins play specific roles or the complex functions as a single unit. In the present study, we examined the requirement and role for the individual disulfide bonds of Tim9 on cell viability, complex formation and stability using yeast genetic, biochemical and biophysical methods. Loss of the Tim9 inner disulfide bond led to a temperature-sensitive phenotype and degradation of both Tim9 and Tim10. The growth phenotype could be suppressed by deletion of the mitochondrial i-AAA (ATPases associated with diverse cellular activities) protease Yme1, and this correlates strongly with stabilization of the Tim10 protein regardless of Tim9 levels. Formation of both disulfide bonds is not essential for Tim9 function, but it can facilitate the formation and improve the stability of the hexameric Tim9-Tim10 complex. Furthermore, our results suggest that the primary function of Tim9 is to protect Tim10 from degradation by Yme1 via assembly into the Tim9-Tim10 complex. We propose that Tim10, rather than the hexameric Tim9-Tim10 complex, is the functional form of these proteins. © 2015 The Author(s).

  11. Corner Office: EBSCO's Tim Collins

    Science.gov (United States)

    Fialkoff, Francine; Oder, Norman

    2008-01-01

    This article presents an interview with Tim Collins, president of EBSCO Publishing. The amiable Collins put EBSCO Publishing (EP) on the map through a combination of first-rate search and user-friendly interfaces, a long list of strategic acquisitions, and a dedicated, stable staff. Now, the company Collins has nurtured for over two decades ranks…

  12. PENGARUH INSTRUMENTAL DAN EXPRESSIVE NETWORK DENSITY TERHADAP KINERJA TIM: PEMEDIASI KEMAMPUAN INTEGRASI PENGETAHUAN TIM

    Directory of Open Access Journals (Sweden)

    Candra Vionela Merdiana

    2016-01-01

    Full Text Available Penelitian ini bertujuan untuk menguji dan menganalisis instrumental network density dan expressive network density terhadap kinerja tim yang dimediasi oleh kemampuan integrasi pengetahuan tim. Penelitian ini merupakan penelitian kuantitatif dengan menggunakan metode survey, sedangkan teknik sampling menggunakan non probability sampling dengan metode purposive sampling. Unit analisis berada pada level tim yang dilakukan pada tim mahasiswa KKN di Universitas Gadjah Mada dan Universitas Negeri Yogyakarta. Setelah dilakukan agregasi, jumlah tim yang digunakan sebanyak 37 tim dengan jumlah kuesioner sebanyak 341 kuesioner. Pengujian untuk mengetahui adanya pengaruh dari mediasi dilakukan dengan menggunakan analisis regresi linier berganda (Baron dan Kenny, 1986. Berdasarkan pengujian dan analisis data, maka diperoleh hasil sebagai berikut : instrumental network density dan expressive network density berpengaruh positif dan signifikan terhadap kinerja tim, kemampuan integrasi pengetahuan tim tidak memediasi pengaruh instrumental network density terhadap kinerja tim, kemampuan integrasi pengetahuan tim tidak memediasi expressive network density terhadap kinerja tim.Kata kunci: Instrumental Network Density, Expressive Network Density, Kemampuan Integrasi Pengetahuan Tim dan Kinerja Tim.

  13. The TNO gastro-intestinal model (TIM)

    NARCIS (Netherlands)

    Minekus, M.

    2015-01-01

    The TNO Gastro–Intestinal Model (TIM) is a multi–compartmental model, designed to realistically simulate conditions in the lumen of the gastro–intestinal tract. TIM is successfully used to study the gastro–intestinal behavior of a wide variety of feed, food and pharmaceutical products. Experiments

  14. Bjerknes, Prof. Vilheim Friman Koren

    Indian Academy of Sciences (India)

    Academy Public Lecture. Posted on 19 January 2018. Seasonal and Pandemic Influenza by Prof. Kanta Subbarao 25 January 2018 at 1600 hrs. Ground floor, Main auditorium, New Biological Sciences Building, IISc. Event Poster ...

  15. Varadhan, Prof. Srinivasa S R

    Indian Academy of Sciences (India)

    Varadhan, Prof. Srinivasa S R . Date of birth: 2 January 1940. Address: Department of Mathematics, Courant Institute, New York University, 251, Mercer Street, New York, NY 10012, U.S.A.. Contact: Office: (+1-212) 982 9883

  16. Alfven, Prof. Hannes Olof Gosta

    Indian Academy of Sciences (India)

    Alfven, Prof. Hannes Olof Gosta Nobel Laureate (Physics) - 1970. Date of birth: 30 May 1908. Date of death: 2 April 1995. YouTube; Twitter ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  17. Krogh, Prof. Schack August Steenberg

    Indian Academy of Sciences (India)

    Krogh, Prof. Schack August Steenberg Nobel Laureate (Medicine) - 1920. Date of birth: 15 November 1874. Date of death: 13 September 1949 ... Summer Schools. Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach.

  18. Dirac, Prof. Paul Adrien Maurice

    Indian Academy of Sciences (India)

    Dirac, Prof. Paul Adrien Maurice Nobel Laureate (Physics) - 1933. Date of birth: 8 August 1902. Date of death: 20 October 1984. YouTube ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  19. Heymaans, Prof. Corneille Jean Francois

    Indian Academy of Sciences (India)

    Heymaans, Prof. Corneille Jean Francois Nobel Laureate (Medicine) - 1938. Date of birth: 28 March 1892. Date of death: 18 July 1968 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  20. Domagk, Prof. Gerhard Johannes Paul

    Indian Academy of Sciences (India)

    Domagk, Prof. Gerhard Johannes Paul Nobel Laureate (Medicine) - 1939. Date of birth: 30 October 1895. Date of death: 24 April 1964 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  1. Brumpt, Prof. Emile Joseph Alexandre

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1936 Honorary. Brumpt, Prof. Emile Joseph Alexandre. Date of birth: 10 March 1877. Date of death: 8 July 1951 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  2. Profile Interview: Prof. Rob Moodie

    African Journals Online (AJOL)

    health leaders such as Jonathan Mann and Daniel Tarantola. We moved back ... We were starting to slow down our moves by then and we ... Profile Interview: Prof. Rob Moodie. “Get up. Do good. Be good. Be.” foundation to use a tax on tobacco to buy out and replace tobacco industry sponsorship in sports and the arts, and.

  3. Rao, Prof. Paranandi Venkata Suryanarayana

    Indian Academy of Sciences (India)

    Elected: 1974 Section: Engineering & Technology. Rao, Prof. Paranandi Venkata Suryanarayana Ph.D. (Mumbai), FNA, FNASc, FNAE. Date of birth: 17 July 1936. Specialization: Computer Science & Speech Research, Natural Language Processing and Cursive Script Recognition Address: Flat No. 601, Vigyan, Sector 17, ...

  4. Bjerknes, Prof. Jacob Aall Bonneveie

    Indian Academy of Sciences (India)

    ... Mid Year Meetings · Discussion Meetings · Public Lectures · Lecture Workshops · Refresher Courses · Symposia · Live Streaming. Home; Fellowship. Fellow Profile. Elected: 1959 Honorary. Bjerknes, Prof. Jacob Aall Bonneveie. Date of birth: 2 November 1897. Date of death: 7 July 1975. YouTube; Twitter; Facebook; Blog ...

  5. Thomas, Prof. Sir John Meurig

    Indian Academy of Sciences (India)

    Thomas, Prof. Sir John Meurig FRS. Date of birth: 15 December 1932. Address: Department of Materials Science and, Metallurgy, New Museums Site, 27, Babbage Road, Cambridge CB3 0FS, U.K.. Contact: Office: (+44-1223) 33 4300. Fax: (+44-1223) 33 4567. Email: jmt2@cam.ac.uk. YouTube; Twitter; Facebook; Blog ...

  6. C V Prof. Yash Pal

    Indian Academy of Sciences (India)

    Elected: 1967 Section: Physics. Pal, Prof. Yash Ph.D. (MIT), FNA Council Service: 1974-76. Date of birth: 26 November 1926. Date of death: 24 July 2017. Specialization: Physics, Astrophysics, Space Technology and Communications Last known address: 11B, Super Delux Flats, Sector 15A, Noida 201 301, U.P.. YouTube ...

  7. Forssmann, Prof. Werner Theodor Otto

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1967 Honorary. Forssmann, Prof. Werner Theodor Otto Nobel Laureate (Medicine) - 1956. Date of birth: 29 August 1904. Date of death: 1 June 1979. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by ...

  8. Valiathan, Prof. Marthanda Varma Sankaran

    Indian Academy of Sciences (India)

    Valiathan, Prof. Marthanda Varma Sankaran Ch.M. (Liverpool), FRCS (England, Edinburgh & Canada), FRCP (London), D.Sc. (h.c.), FNA, FNASc, FNAE, FAMS, FTWAS Council Service: 1980-91; Vice-President: 1986-91. Date of birth: 24 May 1934. Specialization: Cardiac Surgery, Cardiovascular Materials and Ayurveda

  9. Rao, Prof. Manchanahalli Rangaswamy Satyanarayana

    Indian Academy of Sciences (India)

    Elected: 1988 Section: General Biology. Rao, Prof. Manchanahalli Rangaswamy Satyanarayana Ph.D. (IISc), FNA, FNASc, FTWAS, FAMS Council Service: 2013-; Vice President: 2013-. Date of birth: 21 January 1948. Specialization: RNA Biology, Molecular Biology, Cell Biology, Neurooncology Address: Honorary ...

  10. Mohan Ram, Prof. Holenarasipur Yoganarasimham

    Indian Academy of Sciences (India)

    Mohan Ram, Prof. Holenarasipur Yoganarasimham Ph.D. (Delhi), FNA, FNASc, FNAAS Council Service: 1983-88; Vice-President: 1986-88. Date of birth: 24 September 1930. Specialization: Plant Growth & Development and Economic Botany Address: No. 174, SFS DDA Flats, Mukherjee Nagar, Delhi 110 009, U.T.

  11. Krishna Murty, Prof. Achyutuni Venkata

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1993 Section: Engineering & Technology. Krishna Murty, Prof. Achyutuni Venkata Ph.D. (IISc). Date of birth: 10 October 1938. Specialization: Aerospace Engineering, Structural Mechanics, Composites and Smart Structures Address: No. 8, 5th Main, II Cross, NTI Layout, RMV II Stage, Nagashettyhalli, ...

  12. Das Gupta, Prof. Chanchal Kumar

    Indian Academy of Sciences (India)

    Elected: 1998 Section: General Biology. Das Gupta, Prof. Chanchal Kumar Ph.D. (Calcutta), FNASc, FNA. Date of birth: 9 November 1945. Specialization: Genetic Recombination and Protein Folding Address: EE-72/2, Sector II, Salt Lake, Kolkata 700 091, W.B.. Contact: Residence: (033) 4006 5279. Mobile: 90078 89857

  13. Murty, Prof. Sripada Venkata Satyasuryanarayana

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  14. Baba, Prof. Chanduri Venkatasatya Kusumahara

    Indian Academy of Sciences (India)

    Elected: 1977 Section: Physics. Baba, Prof. Chanduri Venkatasatya Kusumahara Ph.D. (Mumbai). Date of birth: 2 October 1937. Date of death: 5 December 2006. Specialization: Nuclear Reactions Last known address: 8-3-169/113, 2D,, Pallavi Apartments, Siddarthnagar, Hyderabad 500 890. YouTube; Twitter; Facebook ...

  15. Levi-Civita, Prof. Tullio

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1938 Honorary. Levi-Civita, Prof. Tullio. Date of birth: 29 March 1873. Date of death: 29 December 1941. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. New Fellows and Honorary Fellow. Posted on 1 January 2018. List of Fellows and Honorary Fellow elected ...

  16. Dam, Prof. Carl Peter Henrik

    Indian Academy of Sciences (India)

    ... Meetings · Public Lectures · Lecture Workshops · Refresher Courses · Symposia · Live Streaming. Home; Fellowship. Fellow Profile. Elected: 1965 Honorary. Dam, Prof. Carl Peter Henrik Nobel Laureate (Medicine) - 1943. Date of birth: 21 February 1895. Date of death: 17 April 1976. YouTube; Twitter; Facebook; Blog ...

  17. Geim, Prof. Sir Andre Konstantin

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2015 Honorary. Geim, Prof. Sir Andre Konstantin FRS. Date of birth: 21 October 1958. Address: Royal Society Research Professor, University of Manchester, Oxford Road, Manchester M13 9PL, UK Contact: Office: (+44-161) 275 4120. Email: geim@manchester.ac.uk. YouTube; Twitter; Facebook ...

  18. Hevesy, Prof. George Charles de

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1951 Honorary. Hevesy, Prof. George Charles de. Date of birth: 1 August 1885. Date of death: 5 July 1966. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on ...

  19. Kohlrausch, Prof. Karl Wilhelm Friedrich

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1939 Honorary. Kohlrausch, Prof. Karl Wilhelm Friedrich. Date of birth: 7 July 1884. Date of death: 17 September 1953. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies ...

  20. Blackett, Prof. Patrick Maynerd Stuart.

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1949 Honorary. Blackett, Prof. Patrick Maynerd Stuart. Nobel Laureate (Physics) - 1948. Date of birth: 17 November 1897. Date of death: 14 July 1974. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement ...

  1. Debye, Prof. Peter Joseph William

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1938 Honorary. Debye, Prof. Peter Joseph William Nobel Laureate (Chemistry) - 1936. Date of birth: 24 March 1884. Date of death: 2 November 1966. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement ...

  2. Joliot-Curie, Prof. Irene

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Joliot-Curie, Prof. Irene Nobel Laureate (Chemistry) - 1935. Date of birth: 12 September 1897. Date of death: 17 March 1956. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  3. Broglie, Prof. Louis Victor de

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1951 Honorary. Broglie, Prof. Louis Victor de. Nobel Laureate (Physics) - 1929. Date of birth: 15 August 1892. Date of death: 19 March 1987. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. New Fellows and Honorary Fellow. Posted on 1 January 2018. List of Fellows ...

  4. Bohr, Prof. Niels Henrik David

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Bohr, Prof. Niels Henrik David Nobel Laureate (Physics) - 1922. Date of birth: 7 October 1885. Date of death: 18 November 1962. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. New Fellows and Honorary Fellow. Posted on 1 January 2018.

  5. Patel, Prof. Chandra Kumar Naranbhai

    Indian Academy of Sciences (India)

    Elected: 1995 Section: Patel, Prof. Chandra Kumar Naranbhai. Date of birth: 2 July 1938. Address: President & CEO, Pranalytica Inc., 1101, Colorado Avenue, Santa Monica, CA 90401, U.S.A.. Contact: Office: (+1-310) 458 0808. Residence: (+1-310) 471 6505. Fax: (+1-310) 458 0171. Email: patel@pranalytica.com.

  6. Bhattacharya, Prof. Sudha Fellow profile

    Indian Academy of Sciences (India)

    Elected: 2001 Section: General Biology. Bhattacharya, Prof. Sudha Ph.D. (IARI, New Delhi), FNASc, FNA Council Service: 2016. Date of birth: 7 March 1952. Specialization: Molecular Biology, Molecular Parasitology and Genomics Address: Professor, School of Environmental Sciences, Jawaharlal Nehru University, New ...

  7. Guha-Mukherjee, Prof. Sipra

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1988 Section: Plant Sciences. Guha-Mukherjee, Prof. Sipra Ph.D. (Delhi), FNASc. Date of birth: 30 July 1938. Date of death: 15 September 2007. Specialization: Plant Molecular Biology, Plant Tissue Culture and Genetic Engineering Last known address: Garden Estate, M A 1/6-3C, Gurgaon 122 002.

  8. TIM-family proteins inhibit HIV-1 release.

    Science.gov (United States)

    Li, Minghua; Ablan, Sherimay D; Miao, Chunhui; Zheng, Yi-Min; Fuller, Matthew S; Rennert, Paul D; Maury, Wendy; Johnson, Marc C; Freed, Eric O; Liu, Shan-Lu

    2014-09-02

    Accumulating evidence indicates that T-cell immunoglobulin (Ig) and mucin domain (TIM) proteins play critical roles in viral infections. Herein, we report that the TIM-family proteins strongly inhibit HIV-1 release, resulting in diminished viral production and replication. Expression of TIM-1 causes HIV-1 Gag and mature viral particles to accumulate on the plasma membrane. Mutation of the phosphatidylserine (PS) binding sites of TIM-1 abolishes its ability to block HIV-1 release. TIM-1, but to a much lesser extent PS-binding deficient mutants, induces PS flipping onto the cell surface; TIM-1 is also found to be incorporated into HIV-1 virions. Importantly, TIM-1 inhibits HIV-1 replication in CD4-positive Jurkat cells, despite its capability of up-regulating CD4 and promoting HIV-1 entry. In addition to TIM-1, TIM-3 and TIM-4 also block the release of HIV-1, as well as that of murine leukemia virus (MLV) and Ebola virus (EBOV); knockdown of TIM-3 in differentiated monocyte-derived macrophages (MDMs) enhances HIV-1 production. The inhibitory effects of TIM-family proteins on virus release are extended to other PS receptors, such as Axl and RAGE. Overall, our study uncovers a novel ability of TIM-family proteins to block the release of HIV-1 and other viruses by interaction with virion- and cell-associated PS. Our work provides new insights into a virus-cell interaction that is mediated by TIMs and PS receptors.

  9. Mast cell activation is enhanced by Tim1:Tim4 interaction but not by Tim-1 antibodies [version 2; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Binh Phong

    2016-07-01

    Full Text Available Polymorphisms in the T cell (or transmembrane immunoglobulin and mucin domain 1 (TIM-1 gene, particularly in the mucin domain, have been associated with atopy and allergic diseases in mice and human. Genetic- and antibody-mediated studies revealed that Tim-1 functions as a positive regulator of Th2 responses, while certain antibodies to Tim-1 can exacerbate or reduce allergic lung inflammation. Tim-1 can also positively regulate the function of B cells, NKT cells, dendritic cells and mast cells. However, the precise molecular mechanisms by which Tim-1 modulates immune cell function are currently unknown. In this study, we have focused on defining Tim-1-mediated signaling pathways that enhance mast cell activation through the high affinity IgE receptor (FceRI. Using a Tim-1 mouse model lacking the mucin domain (Tim-1Dmucin, we show for the first time that the polymorphic Tim-1 mucin region is dispensable for normal mast cell activation. We further show that Tim-4 cross-linking of Tim-1 enhances select signaling pathways downstream of FceRI in mast cells, including mTOR-dependent signaling, leading to increased cytokine production but without affecting degranulation.

  10. King, Prof. Sir David Anthony

    Indian Academy of Sciences (India)

    Elected: 1998 Honorary. King, Prof. Sir David Anthony Sc.D., FRS. Date of birth: 12 August 1939. Address: Chief Scientific Adivser & Head, Office of Science and Innovation, London SW1H 0ET, U.K.. Contact: Office: (+44-020) 7215 3821. Fax: (+44-020) 7215 0314. Email: mpst.king@dti.gsi.gov.uk, dak10@cus.cam.ac.uk.

  11. Immune Regulation and Antitumor Effect of TIM-1

    Directory of Open Access Journals (Sweden)

    Peng Du

    2016-01-01

    Full Text Available T cells play an important role in antitumor immunity, and the T cell immunoglobulin domain and the mucin domain protein-1 (TIM-1 on its surface, as a costimulatory molecule, has a strong regulatory effect on T cells. TIM-1 can regulate and enhance type 1 immune response of tumor association. Therefore, TIM-1 costimulatory pathways may be a promising therapeutic target in future tumor immunotherapy. This review describes the immune regulation and antitumor effect of TIM-1.

  12. Thermal Infrared Multispectral Scanner (TIMS): An investigator's guide to TIMS data

    Science.gov (United States)

    Palluconi, F. D.; Meeks, G. R.

    1985-01-01

    The Thermal Infrared Multispectral Scanner (TIMS) is a NASA aircraft scanner providing six channel spectral capability in the thermal infrared region of the electromagnetic spectrum. Operating in the atmospheric window region (8 to 12 micrometers) with a channel sensitivity of approximately 0.1 C, TIMS may be used whenever an accurate measure of the Earth's surface is needed. A description of this scanner is provided as well as a discussion of data acquisition and reduction.

  13. Brown Syndrome

    Science.gov (United States)

    ... extraction) have also been linked to acquired Brown syndrome. Inflammation of the tendon-trochlea complex (from adult and juvenile rheumatoid arthritis, systemic lupus erythematosus and sinusitis) can be ... syndrome hereditary? Hereditary cases of Brown syndrome are rare. ...

  14. In Memoriam- Prof. Dr. Andries Willem Lategan

    Directory of Open Access Journals (Sweden)

    S. P. Ligthelm

    1965-03-01

    Full Text Available Hierdie Curriculum Vitae sou voorgelees gewees het met die inougurele rede van wyle prof. dr. A. W. Lategan met die aanvaarding van 'n ereprofessoraat aan die P.U. vir C.H.O. op 29 Oktober 1965. Prof. Lategan is op 23 Oktober 1965 oor- lcde. Sy inougurele rede verskyn as ’n bylaag in hierdie uit- gawe.

  15. Tim-3 expression in cervical cancer promotes tumor metastasis.

    Directory of Open Access Journals (Sweden)

    Yang Cao

    Full Text Available T cell immunoglobulin mucin-3 (Tim-3 has been identified as a negative regulator of anti-tumor immunity. Recent studies highlight the important role of Tim-3 in the CD8(+ T cell exhaustion that takes place in both human and animal cancer models. However, the nature of Tim-3 expression in the tumor cell and the mechanism by which it inhibits anti-tumor immunity are unclear. This present study aims to determine Tim-3 is expressed in cervical cancer cells and to evaluate the role of Tim-3 in cervical cancer progression.A total of 85 cervical tissue specimens including 43 human cervical cancer, 22 cervical intraepithelial neoplasia (CIN and 20 chronic cervicitis were involved. Tim-3 expression in tumor cells was detected and was found to correlate with clinicopathological parameters. Meanwhile, expression of Tim-3 was assessed by RT-PCR, Western Blot and confocal microscopy in cervical cancer cell lines, HeLa and SiHa. The migration and invasion potential of Hela cells was evaluated after inhibiting Tim-3 expression by ADV-antisense Tim-3.We found that Tim-3 was expressed at a higher level in the clinical cervical cancer cells compared to the CIN and chronic cervicitis controls. We supported this finding by confirming the presence of Tim-3 mRNA and protein in the cervical cell lines. Tim-3 expression in tumor cells correlated with clinicopathological parameters. Patients with high expression of Tim-3 had a significant metastatic potential, advanced cancer grades and shorter overall survival than those with lower expression. Multivariate analysis showed that Tim-3 expression was an independent factor for predicting the prognosis of cervical cancer. Significantly, down-regulating the expression of Tim-3 protein inhibited migration and invasion of Hela cells. Our study suggests that the expression of Tim-3 in tumor cells may be an independent prognostic factor for patients with cervical cancer. Moreover, Tim-3 expression may promote metastatic

  16. Tim-3 expression defines regulatory T cells in human tumors.

    Directory of Open Access Journals (Sweden)

    Jing Yan

    Full Text Available Tim-3, a member of the novel Tim (T cell immunoglobulin and mucin domain family, has been reported to negatively regulate the immune responses against viral infection and had implications for autoimmune disease. However, the nature and role of Tim-3(+ CD4 T cells in human tumors remain largely unknown. In the present study, we characterized Tim-3(+ CD4 T cells in 100 specimens from human hepatocellular, cervical, colorectal and ovarian carcinoma patients. Compared with peripheral blood and nontumor-infiltrating lymphocytes, the lymphocytes isolated from the corresponding tumor tissues of hepatocellular, cervical, colorectal and ovarian carcinoma patients contained significantly greater proportion of Tim-3(+ CD4 T cells. The majority of tumor-derived Tim-3(+ CD4 T cells exhibited an impaired capacity to produce IFN-γ and IL-2, but expressed higher levels of CD25, Foxp3, CTLA-4 and GITR than their Tim-3(- CD4 T cell counterparts. In contrast, most Tim-3(+ CD4 T cells isolated from the paired nontumor tissues and peripheral blood did not express these molecules. Moreover, tumor-derived Tim-3(+ CD4 T cells, but not tumor-derived Tim-3(- CD4 T cells, significantly suppressed the proliferation of autologous CD8(+ T cells in vitro. Notably, multi-color immunofluorescence and confocal microscopy demonstrated that Tim-3(+Foxp3(+CD4(+ cells were preferentially distributed in the tumor nest rather than the peritumoral stroma of hepatocellular carcinoma. Together, our data indicate that Tim-3-expressing CD4 T cells in human tumors could represent the functional regulatory T cells which contribute to the formation of the immune-suppressive tumor micromilieu.

  17. Frey-Wyssling, Prof. Albert Friedrich

    Indian Academy of Sciences (India)

    Academy Public Lecture. Posted on 19 January 2018. Seasonal and Pandemic Influenza by Prof. Kanta Subbarao 25 January 2018 at 1600 hrs. Ground floor, Main auditorium, New Biological Sciences Building, IISc. Event Poster ...

  18. Commemorating the passing of Prof. Kazuo Akiyama

    National Research Council Canada - National Science Library

    Masami Taniguchi

    2015-01-01

    On November 3, 2014, Prof. Kazuo Akiyama, who was the Director of Sagamihara National Hospital, Kanagawa, Japan and had served as the President of the Japanese Society of Allergology for two terms, passed away...

  19. Analysis and production of the traffic incident management state self-assessments (TIM SA) national report.

    Science.gov (United States)

    2008-09-29

    The Traffic Incident Management Self-Assessment (TIM SA) provides a means for evaluating progress in achievement of individual TIM program components and overall TIM program success in three areas: Program and Institutional Issues; Operational Issues...

  20. Tim Berners-Lee and Kofi Annan during the WSIS

    CERN Document Server

    Patrice Loïez

    2003-01-01

    During the 2003 World Summit on the Information Society (WSIS) at Geneva Palexpo, Tim Berners-Lee W3C's director (World Wide Web consortium) was introduced to Kofi Annan, Secretary General of the United Nations. Tim Berners-Lee developed the first network and server system that lead to the World Wide Web.

  1. Tim Berners-Lee and Kofi Annan during the WSIS

    CERN Document Server

    Patrice Loïez

    2003-01-01

    During the 2003 World Summit on the Information Society (WSIS) at Geneva Palexpo, Tim Berners-Lee, W3C's director (World Wide Web consortium) was introduced to Kofi Annan, Secretary General of the United Nations. Tim Berners-Lee developed the first network and server system that lead to the World Wide Web.

  2. Tim Berners-Lee receives the Millennium Technology Prize

    CERN Multimedia

    2004-01-01

    On 15 April, for his invention of the Web, Tim Berners-Lee was awarded the first ever Millennium Technology Prize by the Finnish Technology Award Foundation, which recognises technological innovations of lasting benefit to society. "Tim Berners-Lee's invention perfectly encapsulates the spirit of the Prize. The Web is encouraging new types of social networks, contributing to transparency and democracy, and opening up new avenues for information management and business development," underlined Pekka Tarjanne, chairman of the jury and former Secretary-General of the International Telecommunication Union (ITU). Tim Berners-Lee is congratulated by Jukka Valtasaari, Finland's Ambassador to the United States. Tim Berners-Lee created the first server, browser and editor, the HTML code, the URL address and the HTTP transmission protocol at CERN in 1990. CERN released the Web into the public domain in 1993. Tim Berners-Lee is currently head of the World Wide Web Consortium, managed by ERCIM (Europe...

  3. Tim Peake and Britain's road to space

    CERN Document Server

    Seedhouse, Erik

    2017-01-01

    This book puts the reader in the flight suit of Britain’s first male astronaut, Tim Peake. It chronicles his life, along with the Principia mission and the down-to-the-last-bolt descriptions of life aboard the ISS, by way of the hurdles placed by the British government and the rigors of training at Russia’s Star City military base. In addition, this book discusses the learning curves required in astronaut and mission training and the complexity of the technologies required to launch an astronaut and keep them alive for months on end. This book underscores the fact that technology and training, unlike space, do not exist in a vacuum; complex technical systems, like the ISS, interact with the variables of human personality, and the cultural background of the astronauts. .

  4. Project TIMS (Teaching Integrated Math/Science)

    Science.gov (United States)

    Edwards, Leo, Jr.

    1993-01-01

    The goal of this project is to increase the scientific knowledge and appreciation bases and skills of pre-service and in-service middle school teachers, so as to impact positively on teaching, learning, and student retention. This report lists the objectives and summarizes the progress thus far. Included is the working draft of the TIMS (Teaching Integrated Math/Science) curriculum outline. Seven of the eight instructional subject-oriented modules are also included. The modules include informative materials and corresponding questions and educational activities in a textbook format. The subjects included here are the universe and stars; the sun and its place in the universe; our solar system; astronomical instruments and scientific measurements; the moon and eclipses; the earth's atmosphere: its nature and composition; and the earth: directions, time, and seasons. The module not included regards winds and circulation.

  5. Validation of the Glory TIM and a Ground-Based SORCE TIM (Invited)

    Science.gov (United States)

    Harber, D.; Heuerman, K.; Kopp, G.

    2010-12-01

    The total solar irradiance (TSI) climate data record is essential for detecting potential long-term solar variability and estimating climate sensitivity to solar forcing. This data record currently relies on measurements from over 10 different spaceborne radiometers. Because differences between instruments exceed the stated individual instrument uncertainties, the data record to date has depended on overlapping measurements to adjust for offsets in order to generate a single continuous record. This technique is only possible with continuous and overlapping measurements. The risk of loss of continuity in this 32-year record drives the need for a strategy that is robust to a loss of continuity via improved absolute accuracies. Such an approach requires instruments with solar power with accuracies approaching this level. The first such facility in the world, the TRF allows direct irradiance comparisons between a TSI instrument under test and a NIST-calibrated reference cryogenic radiometer viewing the same uniform input light beam in a common vacuum system. The NASA Glory mission’s Total Irradiance Monitor (TIM), a TSI instrument that is planned for launch in 2010 with a design similar to the SORCE TIM, was validated in the TRF in March-April 2010, and a ground-based SORCE TIM has been similarly validated. Results of these inter-comparisons will be presented.

  6. TIM-1 signaling in B cells regulates antibody production.

    Science.gov (United States)

    Ma, Juan; Usui, Yoshihiko; Takeda, Kazuyoshi; Harada, Norihiro; Yagita, Hideo; Okumura, Ko; Akiba, Hisaya

    2011-03-11

    Members of the T cell Ig and mucin (TIM) family have recently been implicated in the control of T cell-mediated immune responses. In this study, we found TIM-1 expression on anti-IgM- or anti-CD40-stimulated splenic B cells, which was further up-regulated by the combination of anti-IgM and anti-CD40 Abs. On the other hand, TIM-1 ligand was constitutively expressed on B cells and inducible on anti-CD3(+) anti-CD28-stimulated CD4(+) T cells. In vitro stimulation of activated B cells by anti-TIM-1 mAb enhanced proliferation and expression of a plasma cell marker syndecan-1 (CD138). We further examined the effect of TIM-1 signaling on antibody production in vitro and in vivo. Higher levels of IgG2b and IgG3 secretion were detected in the culture supernatants of the anti-TIM-1-stimulated B cells as compared with the control IgG-stimulated B cells. When immunized with T-independent antigen TNP-Ficoll, TNP-specific IgG1, IgG2b, and IgG3 Abs were slightly increased in the anti-TIM-1-treated mice. When immunized with T-dependent antigen OVA, serum levels of OVA-specific IgG2b, IgG3, and IgE Abs were significantly increased in the anti-TIM-1-treated mice as compared with the control IgG-treated mice. These results suggest that TIM-1 signaling in B cells augments antibody production by enhancing B cell proliferation and differentiation. Copyright © 2011 Elsevier Inc. All rights reserved.

  7. The early Browning: Pastoral care in a pluralistic age and the method of practical moral inquiry

    Directory of Open Access Journals (Sweden)

    Mark Hestenes

    2012-02-01

    Full Text Available The past president of the International Academy of Practical Theology, Prof. Donald Browning, has written books and articles across a wide variety of topics concerning the correlation of many great fields of knowledge, including theology, psychology, philosophy, sociology, practical theology, ethics, family therapy and ecology over the past 40 years. Prof. Browning passed away on 03 June 2010. This left the author of this article with a desire to begin to reassess some of Browning’s earlier reflections regarding his vision of pastoral care in a pluralistic age and the importance of his method of practical moral inquiry.

  8. Response to Tim Barringer, A White Atlantic?

    Directory of Open Access Journals (Sweden)

    Kate Flint

    2009-11-01

    Full Text Available In my response to Tim Barringer’s piece, I emphasize the importance of extending one’s frame of reference when discussing transatlantic artistic connections to the consideration of as many different art forms as possible – including photography, and magazine and book illustrations – in order to get as full a picture as possible of the two-way flow in transatlantic artistic influences.This fuller picture notably extends the degree to which images of non-white subjects are seen to be in circulation. I also draw attention to the ways in which American and English artistic circles intersected outside as well as within these two countries, a point reinforced by looking at American women sculptors in Rome in the 1860s, paying particular attention to the work of the part African-American, part Native American sculptor, Edmonia Lewis. In her work can be seen a complex set of attitudes towards her subject matter that remind one forcefully of the many racial and cultural strands coming together in new American art.

  9. Cultura digital jovem: as TIMS invadem as periferias, e agora?

    National Research Council Canada - National Science Library

    Márcia Gonçalves Nogueira; Maria Auxiliadora Soares Padilha

    2014-01-01

    Objective of this work is to present a literature review on Young and the Digital Cultural transformations caused by the dissemination of Information Technology and Communication Mobile and wireless (TIMS...

  10. Meet EPA Scientist Tim Shafer, Ph.D.

    Science.gov (United States)

    Tim Shafer earned his bachelor’s degree in biology and chemistry from Hope College in Holland, MI, in 1986 and his Ph.D. in pharmacology and environmental toxicology from Michigan State University in 1991.

  11. Tim Berners-Lee, World Wide Web inventor

    CERN Document Server

    1994-01-01

    Former physicist, Tim Berners-Lee invented the World Wide Web as an essential tool for high energy physics at CERN from 1989 to 1994. Together with a small team he conceived HTML, http, URLs, and put up the first server and the first 'what you see is what you get' browser and html editor. Tim is now Director of the Web Consortium W3C, the International Web standards body based at INRIA, MIT and Keio University.

  12. Isotopic Ratios of Samarium by TIMS for Nuclear Forensic Application

    Energy Technology Data Exchange (ETDEWEB)

    Louis Jean, James [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Inglis, Jeremy David [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-08-08

    The isotopic ratio of Nd, Sm, and Gd can provide important information regarding fissile material (nuclear devices, reactors), neutron environment, and device yield. These studies require precise measurement of Sm isotope ratios, by either TIMS or MC-ICP-MS. There has been an increasing trend to measure smaller and smaller quantities of Sm bearing samples. In nuclear forensics 10-100 ng of Sm are needed for precise measurement. To measure sub-ng Sm samples using TIMS for nuclear forensic analysis.

  13. Unmaking Brown

    Science.gov (United States)

    Lockette, Tim

    2010-01-01

    America's schools are more segregated now than they were in the late 1960s. More than 50 years after "Brown v. Board of Education," educators need to radically rethink the meaning of "school choice." For decades at Wake County, buses would pick up public school students in largely minority communities along the Raleigh…

  14. There are those who call it...TIM

    CERN Multimedia

    2007-01-01

    To boldly go where people can't... The Train Inspection Monorail, affectionately referred to as 'TIM,' will allow scientists, technicians and engineers to view and take measurements in the LHC tunnel when it is inaccessible to humans. TIM in the tunnel.Jean-Louis Grenard, who designed TIM's mechanical components, uses the portable remote control station to put the TIM through its paces at Point 1 in the LHC. Imagine being able to view parts of the LHC before people are allowed into the tunnel after the beam has been circulating...or to accurately measure the position of equipment in areas with the highest levels of radiation without risking human exposure. The Train Inspection Monorail, or 'TIM' to its closer friends, is a modular train that will run along the ceiling of the LHC tunnel, helping many groups on site to address the problems of inspecting, measuring and even handling equipment in the LHC when radiation levels and cryogenic hazards will restrict personnel access to the tunnel. TIM was developed ...

  15. Euler-Chelpin, Prof. Hans von

    Indian Academy of Sciences (India)

    Euler-Chelpin, Prof. Hans von. Nobel Laureate (Chemistry) - 1929. Date of birth: 15 February 1873. Date of death: 6 November 1964 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  16. Prakasa Rao, Prof. Bhagavatula Lakshmi Surya

    Indian Academy of Sciences (India)

    Prakasa Rao, Prof. Bhagavatula Lakshmi Surya Ph.D. (Michigan State), FNA, FNASc. Date of birth: 6 October 1942. Specialization: Statistics Address: Ramanujan Chair Professor, CR Rao Advanced Institute of Mathematics,, Statistics & Computer Science, University of Hyderabad Campus, Hyderabad 500 046, A.P.

  17. Sewell, Prof. R.B. Seymour

    Indian Academy of Sciences (India)

    ... Mid Year Meetings · Discussion Meetings · Public Lectures · Lecture Workshops · Refresher Courses · Symposia · Live Streaming. Home; Fellowship. Fellow Profile. Elected: 1949 Honorary. Sewell, Prof. R.B. Seymour. Date of birth: 5 March 1880. Date of death: 10 February 1964. YouTube; Twitter; Facebook; Blog ...

  18. Laue, Prof. Max Theodor Felix von

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1954 Honorary. Laue, Prof. Max Theodor Felix von. Nobel Laureate (Physics) - 1914. Date of birth: 9 October 1897. Date of death: 24 April 1960. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  19. Prof. KS Krishnan and Crystal Magnetism

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 7; Issue 12. Prof. K S Krishnan and Crystal Magnetism. U S Ghosh. General Article Volume 7 Issue 12 December 2002 pp 65-70. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/007/12/0065-0070. Keywords.

  20. Sopory, Prof. Sudhir Kumar - IAS Fellow

    Indian Academy of Sciences (India)

    Elected: 1992 Section: Plant Sciences. Sopory, Prof. Sudhir Kumar Ph.D. (Delhi), FNA, FNASc, FNAAS, FTWAS Council Service: 2001-2006. Date of birth: 7 January 1948. Specialization: Molecular Plant Physiology and Plant Tissue Culture & Transformation Address: 584, Sector 14, Faridabad 121 007, Haryana Contact:

  1. Prasad, Prof. Yellapregada Venkata Rama Krishna

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1991 Section: Engineering & Technology. Prasad, Prof. Yellapregada Venkata Rama Krishna Ph.D. (IISc), FNA. Date of birth: 21 May 1944. Specialization: Deformation Processing, Process Modelling, Deterministic Chaos and Microstructural Control Address: B/2, Hospital Extension, Vinayaka Nagar, ...

  2. Prof dr FJ van Zyl as sendingteoloog

    Directory of Open Access Journals (Sweden)

    D. J.C. vanWyk

    1989-01-01

    Full Text Available Prof Dr FJ van Zyl as mission theologian In this article, the theology of mission of Prof dr FJ van Zyl is being explored. This is done by way of his lectures in the Science of Mission at the University of Pretoria during 1960-1978 and also from articles in the magazines of the Nederduitsch Hervormde Kerk dating back approximately forty years. It is found that almost none of his dictions is outdated. The radical cataclysm in the theology of mission, especially after 1961, he sharply detected and exposed. His theology of mission is built on a very broad theological base which can be described as theology of the Word. To him mission is proclamation.

  3. A hybrid TIM-NOMA scheme for the Broadcast Channel

    Directory of Open Access Journals (Sweden)

    V. Kalokidou

    2015-07-01

    Full Text Available Future mobile communication networks will require enhanced network efficiency and reduced system overhead. Research on Blind Interference Alignment and Topological Interference Management (TIM has shown that optimal Degrees of Freedom can be achieved, in the absence of Channel State Information at the transmitters. Moreover, the recently emerged Non- Orthogonal Multiple Access (NOMA scheme suggests a different multiple access approach, compared to the orthogonal methods employed in 4G, resulting in high capacity gains. Our contribution is a hybrid TIM-NOMA scheme in K-user cells, where users are divided into T groups. By superimposing users in the power domain, we introduce a two-stage decoding process, managing “inter-group” interference based on the TIM principles, and “intra-group” interference based on Successful Interference Cancellation, as proposed by NOMA. We show that the hybrid scheme can improve the sum rate by at least 100% compared to Time Division Multiple Access, for high SNR values.

  4. Pursuing the impossible: an interview with Tim Hunt.

    Science.gov (United States)

    Hunt, Tim

    2015-08-08

    Tim Hunt took an undergraduate degree in Natural Sciences at Cambridge in 1964, and his PhD and subsequent work focussed on the control of protein synthesis until 1982, when his adventitious discovery of the central cell cycle regulator cyclin, while he was teaching at the Marine Biological Laboratory in Woods Hole, redirected him to the study of cell cycle regulation. From 1990 to his retirement Tim worked in the Clare Hall Laboratories of Cancer Research UK. He shared the Nobel Prize in Physiology and Medicine with Lee Hartwell and Paul Nurse in 2001, and talked to us about the series of coincidences that led him to the prizewinning discovery.

  5. Society News: RAS Awards 2012; Prof. Andy Fabian; Prof. John C Brown; Prof. Andrew Fazakerley; Dr. Mike Irwin; Joss Bland-Hawthorn

    Science.gov (United States)

    2012-02-01

    Each year the RAS recognizes outstanding achievement in astronomy and geophysics by the award of medals and prizes. Candidates are nominated by Fellows and the awards made by a committee of Fellows, ensuring that these scientists have earned the respect and admiration of their peers in the research community.

  6. Frontline Science: Tim-3-mediated dysfunctional engulfment of apoptotic cells in SLE.

    Science.gov (United States)

    Zhao, Di; Guo, Min; Liu, Bing; Lin, Qinghai; Xie, Tingting; Zhang, Qianqian; Jia, Xiaoxia; Shu, Qiang; Liang, Xiaohong; Gao, Lifen; Ma, Chunhong

    2017-07-28

    T cell Ig and mucin domain-containing molecule 3 (Tim-3) has been found to play important roles in autoimmune diseases, but whether Tim-3-mediated engulfment of apoptotic cells is involved in systemic lupus erythematosus (SLE) remains to be elucidated. In this study, we verified the role of human Tim-3 (hTim-3) as the receptor of phosphatidylserine (PS) in human embryonic kidney (HEK)293 cells, which initiated the engulfment of apoptotic cells. Both IgV and the mucin domain of Tim-3 were crucial in the phagocytosis of apoptotic cells, and there existed the key cytoplasmic domain for signal transduction. Alanine at 111, locating around the FG-CC' loop of hTim-3, was necessary for its engulfment of apoptotic cells. In accordance, Tim-3 on CD14(+) cells negatively correlated with the percentage of peripheral apoptotic cells in control subjects. However, although Tim-3 was significantly increased on CD14(+) cells in SLE patients, peripheral apoptotic cells remained much higher than those in control subjects. Tim-3 on CD14(+) cells showed positive correlation with percentage of apoptotic cells and level of dsDNA, indicating the involvement of Tim-3 in SLE. Accordingly, soluble Tim-3 (sTim-3) was significantly increased in plasma of SLE patients, which might contribute to higher expression of a disintegrin and metalloproteinase (ADAM)-10. Pretreatment with both plasma from SLE patients and recombinant sTim-3 greatly inhibited hTim-3-initiated phagocytosis of apoptotic cells. Furthermore, anti-Tim-3 antibody depletion of plasma from SLE patients reversed the decreased phagocytosis of apoptotic cells. Collectively, our data suggest that sTim-3 might play inhibitory roles in impaired Tim-3-mediated clearance of apoptotic cells in SLE. © Society for Leukocyte Biology.

  7. Brown recluse spider (image)

    Science.gov (United States)

    The brown recluse is a venomous spider most commonly found in midwestern and southern states of the United States. It ... inch overall and has long skinny legs. The brown recluse is brown with a characteristic dark violin-shaped ...

  8. Tim Berners-Lee, World Wide Web inventor

    CERN Document Server

    1998-01-01

    The "Internet, Web, What's next?" conference on 26 June 1998 at CERN: Tim Berners-Lee, inventor of the World Wide Web and Director of the W3C, explains how the Web came to be and gave his views on the future.

  9. TIM3 Mediates T Cell Exhaustion during Mycobacterium tuberculosis Infection

    Science.gov (United States)

    Jayaraman, Pushpa; Jacques, Miye K.; Zhu, Chen; Steblenko, Katherine M.; Stowell, Britni L.; Madi, Asaf; Anderson, Ana C.; Kuchroo, Vijay K.; Behar, Samuel M.

    2016-01-01

    While T cell immunity initially limits Mycobacterium tuberculosis infection, why T cell immunity fails to sterilize the infection and allows recrudescence is not clear. One hypothesis is that T cell exhaustion impairs immunity and is detrimental to the outcome of M. tuberculosis infection. Here we provide functional evidence for the development T cell exhaustion during chronic TB. Second, we evaluate the role of the inhibitory receptor T cell immunoglobulin and mucin domain–containing-3 (TIM3) during chronic M. tuberculosis infection. We find that TIM3 expressing T cells accumulate during chronic infection, co-express other inhibitory receptors including PD1, produce less IL-2 and TNF but more IL-10, and are functionally exhausted. Finally, we show that TIM3 blockade restores T cell function and improves bacterial control, particularly in chronically infected susceptible mice. These data show that T cell immunity is suboptimal during chronic M. tuberculosis infection due to T cell exhaustion. Moreover, in chronically infected mice, treatment with anti-TIM3 mAb is an effective therapeutic strategy against tuberculosis. PMID:26967901

  10. Prof. Il-Hoi Kim: a tribute.

    Science.gov (United States)

    Huys, Rony

    2016-10-11

    Prof. Il-Hoi Kim was born during the Korean War on 28 February 1952 in Buan, North Jeolla Province (South Korea), near the coast of the Yellow Sea whose tidal flats would become one of his favourite sampling grounds during his scientific career. From an early age he developed an intense interest in natural history in general and marine biology in particular. He obtained his B.Sc. in 1974 at the Department of Biology Education, Gongju National College of Education. Between 1974 and 1976 he was conscripted into the South Korean military during which he progressed to the rank of lieutenant of artillery in the Reserve Officers' Training Corps (ROTC). After his graduation in 1980 at the Department of Zoology, Seoul National University, Il-Hoi Kim moved to the Department of Biology, Gangneung-Wonju National University on the East Sea coast where he was first appointed lecturer (1981) before taking up the position of assistant professor (1983), associate professor (1987) and full professor (1993). In 1985 he had previously completed his Ph.D. dissertation on Korean barnacles at Seoul National University under the supervision of the late Prof. Hoon Soo Kim, a pioneer in marine invertebrate taxonomy and renowned as the father of carcinology in Korea.

  11. Interview with Prof. Soeren M Bentzen (with english subtitles)

    CERN Multimedia

    Antonella del Rosso

    2012-01-01

    Interview with Prof. Soeren M Benzen, University of Wisconsin, Madison, on the role of physics biology and genomics in cancer treatment today. Interview avec le prof. Soeren Benzen, Université de Wisconsin, Madison, sur le role de la physique, la biologie et la genomique dans le traitement du cancer aujourd'hui.

  12. Prof. Frank Shu | Academy – Springer Nature chair | About IASc ...

    Indian Academy of Sciences (India)

    Academy – Springer Nature chair. Prof Frank Shu. Prof. Frank Shu. Shu is known for pioneering theoretical work in a diverse set of fields of astrophysics, including the origin of meteorites, the birth and early evolution of stars and the structure of spiral galaxies. One of his most highly-cited works is a 1977 seminal paper ...

  13. Prof. S. Dhawan | History | About IASc | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Prof. S. Dhawan. President from 1977 to 1979. Prof. S. Dhawan (1977-1979). Name: DHAWAN, Satish Elected 1970; Council Service: 1971-91; President: 1977-79; Vice-President: 1974-76. Member, Space Commission, Dept. of Space, Bengaluru Date of birth: 25 September 1920, Srinagar, Jammu & Kashmir

  14. Design of symmetric TIM barrel proteins from first principles.

    Science.gov (United States)

    Nagarajan, Deepesh; Deka, Geeta; Rao, Megha

    2015-08-12

    Computational protein design is a rapidly maturing field within structural biology, with the goal of designing proteins with custom structures and functions. Such proteins could find widespread medical and industrial applications. Here, we have adapted algorithms from the Rosetta software suite to design much larger proteins, based on ideal geometric and topological criteria. Furthermore, we have developed techniques to incorporate symmetry into designed structures. For our first design attempt, we targeted the (α/β)8 TIM barrel scaffold. We gained novel insights into TIM barrel folding mechanisms from studying natural TIM barrel structures, and from analyzing previous TIM barrel design attempts. Computational protein design and analysis was performed using the Rosetta software suite and custom scripts. Genes encoding all designed proteins were synthesized and cloned on the pET20-b vector. Standard circular dichroism and gel chromatographic experiments were performed to determine protein biophysical characteristics. 1D NMR and 2D HSQC experiments were performed to determine protein structural characteristics. Extensive protein design simulations coupled with ab initio modeling yielded several all-atom models of ideal, 4-fold symmetric TIM barrels. Four such models were experimentally characterized. The best designed structure (Symmetrin-1) contained a polar, histidine-rich pore, forming an extensive hydrogen bonding network. Symmetrin-1 was easily expressed and readily soluble. It showed circular dichroism spectra characteristic of well-folded alpha/beta proteins. Temperature melting experiments revealed cooperative and reversible unfolding, with a Tm of 44 °C and a Gibbs free energy of unfolding (ΔG°) of 8.0 kJ/mol. Urea denaturing experiments confirmed these observations, revealing a Cm of 1.6 M and a ΔG° of 8.3 kJ/mol. Symmetrin-1 adopted a monomeric conformation, with an apparent molecular weight of 32.12 kDa, and displayed well resolved 1D-NMR spectra

  15. Preliminary crystallographic studies of yeast mitochondrial peripheral membrane protein Tim44p

    Energy Technology Data Exchange (ETDEWEB)

    Josyula, Ratnakar [Department of Cell Biology, Center for Biophysical Sciences and Engineering, University of Alabama at Birmingham (United States); Jin, Zhongmin [SER-CAT, APS, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, IL 60439 (United States); McCombs, Deborah; DeLucas, Lawrence [Center for Biophysical Sciences and Engineering, University of Alabama at Birmingham (United States); Sha, Bingdong, E-mail: bdsha@uab.edu [Department of Cell Biology, Center for Biophysical Sciences and Engineering, University of Alabama at Birmingham (United States)

    2006-02-01

    Tim44p is an essential mitochondrial peripheral membrane protein. To investigate the mechanism by which Tim44p functions in the TIM23 translocon to deliver the mitochondrial protein precursors, the yeast Tim44p has been crystallized. Protein translocations across mitochondrial membranes play critical roles in mitochondrion biogenesis. Protein transport from the cell cytosol to the mitochondrial matrix is carried out by the translocase of the outer membrane (TOM) complex and the translocase of the inner membrane (TIM) complexes. Tim44p is an essential mitochondrial peripheral membrane protein and a major component of the TIM23 translocon. To investigate the mechanism by which Tim44p functions in the TIM23 translocon to deliver the mitochondrial protein precursors, the yeast Tim44p was crystallized. The crystals diffract to 3.2 Å using a synchrotron X-ray source and belong to space group P6{sub 3}22, with unit-cell parameters a = 124.25, c = 77.83 Å. There is one Tim44p molecule in one asymmetric unit, which corresponds to a solvent content of approximately 43%. Structure determination by MAD methods is under way.

  16. TIM-3 does not act as a receptor for galectin-9.

    Directory of Open Access Journals (Sweden)

    Judith Leitner

    2013-03-01

    Full Text Available T cell immunoglobulin and mucin protein 3 (TIM-3 is a type I cell surface protein that was originally identified as a marker for murine T helper type 1 cells. TIM-3 was found to negatively regulate murine T cell responses and galectin-9 was described as a binding partner that mediates T cell inhibitory effects of TIM-3. Moreover, it was reported that like PD-1 the classical exhaustion marker, TIM-3 is up-regulated in exhausted murine and human T cells and TIM-3 blockade was described to restore the function of these T cells. Here we show that the activation of human T cells is not affected by the presence of galectin-9 or antibodies to TIM-3. Furthermore, extensive studies on the interaction of galectin-9 with human and murine TIM-3 did not yield evidence for specific binding between these molecules. Moreover, profound differences were observed when analysing the expression of TIM-3 and PD-1 on T cells of HIV-1-infected individuals: TIM-3 was expressed on fewer cells and also at much lower levels. Furthermore, whereas PD-1 was preferentially expressed on CD45RA(-CD8 T cells, the majority of TIM-3-expressing CD8 T cells were CD45RA(+. Importantly, we found that TIM-3 antibodies were ineffective in increasing anti-HIV-1 T cell responses in vitro, whereas PD-L antibodies potently reverted the dysfunctional state of exhausted CD8 T cells. Taken together, our results are not in support of an interaction between TIM-3 and galectin-9 and yield no evidence for a functional role of TIM-3 in human T cell activation. Moreover, our data indicate that PD-1, but not TIM-3, is a promising target to ameliorate T cell exhaustion.

  17. The new airborne Thermal Infrared Multispectral Scanner (TIMS)

    Science.gov (United States)

    Kahle, A. B.

    1983-01-01

    A new airborne Thermal Infrared Multispectral Scanner (TIMS) with six bands between 8 and 12 microns is briefly characterized, and some results of remote sensing experiments are reported. The instrument has an instantaneous field of view of 2.5 milliradians, a total field of view of 80 deg, and a NE Delta T of approximately 0.1-0.3 C depending on the band. In the TIMS image of Death Valley, silica-rich rocks were easily separable from the nonsilicates. The Eureka Quartzite stood out in sharp contrast to other Ordovician and Cambrian metasediments, and Tertiary volcanic rocks were easily separable from both. Also distinguishable were various units in the fan gravels.

  18. Economist Innovation Award for Tim Berners-Lee

    CERN Multimedia

    2003-01-01

    In September, Tim Berners-Lee, who invented the World Wide Web at CERN and is now Director of the W3C World Wide Web Consortium, received the 2nd Economist Annual Innovation Award in Computing. With the award The Economist, a British weekly newspaper, recognises individuals responsible for breakthroughs in Bioscience, Computing, Energy and the Environment, and Telecommunications that have a profound impact on industry. A fifth award is given in a special "No Boundaries" category, observing innovation that transcends industries. Candidates for the awards are proposed by The Economist readers and writers, and by a group of judges. Tim Berners-Lee received the Computing award for his global hypertext project, to be known as the World Wide Web, which "forever altered the way information is shared" and is a huge contribution to the efficiency of the scientific community. Based on a programme for storing information using random associations called "Enquire", it...

  19. Peripheral blood TIM-3 positive NK and CD8+ T cells throughout pregnancy: TIM-3/galectin-9 interaction and its possible role during pregnancy.

    Science.gov (United States)

    Meggyes, Matyas; Miko, Eva; Polgar, Beata; Bogar, Barbara; Farkas, Balint; Illes, Zsolt; Szereday, Laszlo

    2014-01-01

    The T-cell immunoglobulin and mucin domain (TIM) family is a relatively newly described group of molecules with a conserved structure and important immunological functions. Identification of Galectin-9 as a ligand for TIM-3 has established the Galectin-9/TIM-3 pathway as an important negative regulator of Th1 immunity and tolerance induction. Data about the TIM-3/Gal-9 pathway in the pathogenesis of human diseases is emerging, but their possible role during human pregnancy is not precisely known. The aim of our study was to investigate the number, phenotype and functional activity of TIM-3+ peripheral blood mononuclear cells during healthy human pregnancy. 57 healthy pregnant women [first trimester (n = 16); second trimester (n = 19); third trimester (n = 22)] and 30 non-pregnant controls were enrolled in the study. We measured the surface expression of TIM-3 by cytotoxic T cells, NK cells and NK cell subsets as well as Galectin-9 expression by regulatory T cells by flow cytometry. We analyzed the cytokine production and cytotoxicity of TIM3+ and TIM3- CD8 T and NK cells obtained from non-pregnant and healthy pregnant women at different stages of pregnancy by flow cytometry. Serum Galectin-9 levels were measured by ELISA. Our results show that the numbers of peripheral NK and cytotoxic T cells and their TIM-3 expression do not change between the first, second and third trimesters of pregnancy. Compared to non-pregnant individuals, regulatory T cells show higher level of Galectin-9 expression as pregnancy proceeds, which is in line with the level of Galectin-9 in the patients sera. Cytotoxic T cells, NK cells and NK cell subsets expressing TIM-3 molecule show altered cytokine production and cytotoxicity during pregnancy compared to non-pregnant individuals. Our results indicate that Galectin-9 expressing regulatory T cells, TIM-3+ cytotoxic T cells and NK cells could play an important role in the maintenance of healthy pregnancy.

  20. Techniques for noise removal and registration of TIMS data

    Science.gov (United States)

    Hummer-Miller, S.

    1990-01-01

    Extracting subtle differences from highly correlated thermal infrared aircraft data is possible with appropriate noise filters, constructed and applied in the spatial frequency domain. This paper discusses a heuristic approach to designing noise filters for removing high- and low-spatial frequency striping and banding. Techniques for registering thermal infrared aircraft data to a topographic base using Thematic Mapper data are presented. The noise removal and registration techniques are applied to TIMS thermal infrared aircraft data. -Author

  1. Dr TIM: Ray-tracer TIM, with additional specialist scientific capabilities

    Science.gov (United States)

    Oxburgh, Stephen; Tyc, Tomáš; Courtial, Johannes

    2014-03-01

    We describe several extensions to TIM, a raytracing program for ray-optics research. These include relativistic raytracing; simulation of the external appearance of Eaton lenses, Luneburg lenses and generalised focusing gradient-index lens (GGRIN) lenses, which are types of perfect imaging devices; raytracing through interfaces between spaces with different optical metrics; and refraction with generalised confocal lenslet arrays, which are particularly versatile METATOYs. Catalogue identifier: AEKY_v2_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEKY_v2_0.html Program obtainable from: CPC Program Library, Queen’s University, Belfast, N. Ireland Licencing provisions: GNU General Public License No. of lines in distributed program, including test data, etc.: 106905 No. of bytes in distributed program, including test data, etc.: 6327715 Distribution format: tar.gz Programming language: Java. Computer: Any computer capable of running the Java Virtual Machine (JVM) 1.6. Operating system: Any, developed under Mac OS X Version 10.6 and 10.8.3. RAM: Typically 130 MB (interactive version running under Mac OS X Version 10.8.3) Classification: 14, 18. Catalogue identifier of previous version: AEKY_v1_0 Journal reference of previous version: Comput. Phys. Comm. 183(2012)711 External routines: JAMA [1] (source code included) Does the new version supersede the previous version?: Yes Nature of problem: Visualisation of scenes that include scene objects that create wave-optically forbidden light-ray fields. Solution method: Ray tracing. Reasons for new version: Significant extension of the capabilities (see Summary of revisions), as demanded by our research. Summary of revisions: Added capabilities include the simulation of different types of camera moving at relativistic speeds relative to the scene; visualisation of the external appearance of generalised focusing gradient-index (GGRIN) lenses, including Maxwell fisheye, Eaton and Luneburg lenses; calculation of

  2. TIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserine.

    Directory of Open Access Journals (Sweden)

    Stephanie Jemielity

    2013-03-01

    Full Text Available Human T-cell Immunoglobulin and Mucin-domain containing proteins (TIM1, 3, and 4 specifically bind phosphatidylserine (PS. TIM1 has been proposed to serve as a cellular receptor for hepatitis A virus and Ebola virus and as an entry factor for dengue virus. Here we show that TIM1 promotes infection of retroviruses and virus-like particles (VLPs pseudotyped with a range of viral entry proteins, in particular those from the filovirus, flavivirus, New World arenavirus and alphavirus families. TIM1 also robustly enhanced the infection of replication-competent viruses from the same families, including dengue, Tacaribe, Sindbis and Ross River viruses. All interactions between TIM1 and pseudoviruses or VLPs were PS-mediated, as demonstrated with liposome blocking and TIM1 mutagenesis experiments. In addition, other PS-binding proteins, such as Axl and TIM4, promoted infection similarly to TIM1. Finally, the blocking of PS receptors on macrophages inhibited the entry of Ebola VLPs, suggesting that PS receptors can contribute to infection in physiologically relevant cells. Notably, infection mediated by the entry proteins of Lassa fever virus, influenza A virus and SARS coronavirus was largely unaffected by TIM1 expression. Taken together our data show that TIM1 and related PS-binding proteins promote infection of diverse families of enveloped viruses, and may therefore be useful targets for broad-spectrum antiviral therapies.

  3. TIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserine.

    Science.gov (United States)

    Jemielity, Stephanie; Wang, Jinyize J; Chan, Ying Kai; Ahmed, Asim A; Li, Wenhui; Monahan, Sheena; Bu, Xia; Farzan, Michael; Freeman, Gordon J; Umetsu, Dale T; Dekruyff, Rosemarie H; Choe, Hyeryun

    2013-03-01

    Human T-cell Immunoglobulin and Mucin-domain containing proteins (TIM1, 3, and 4) specifically bind phosphatidylserine (PS). TIM1 has been proposed to serve as a cellular receptor for hepatitis A virus and Ebola virus and as an entry factor for dengue virus. Here we show that TIM1 promotes infection of retroviruses and virus-like particles (VLPs) pseudotyped with a range of viral entry proteins, in particular those from the filovirus, flavivirus, New World arenavirus and alphavirus families. TIM1 also robustly enhanced the infection of replication-competent viruses from the same families, including dengue, Tacaribe, Sindbis and Ross River viruses. All interactions between TIM1 and pseudoviruses or VLPs were PS-mediated, as demonstrated with liposome blocking and TIM1 mutagenesis experiments. In addition, other PS-binding proteins, such as Axl and TIM4, promoted infection similarly to TIM1. Finally, the blocking of PS receptors on macrophages inhibited the entry of Ebola VLPs, suggesting that PS receptors can contribute to infection in physiologically relevant cells. Notably, infection mediated by the entry proteins of Lassa fever virus, influenza A virus and SARS coronavirus was largely unaffected by TIM1 expression. Taken together our data show that TIM1 and related PS-binding proteins promote infection of diverse families of enveloped viruses, and may therefore be useful targets for broad-spectrum antiviral therapies.

  4. Increased bovine Tim-3 and its ligand expressions during bovine leukemia virus infection

    Directory of Open Access Journals (Sweden)

    Okagawa Tomohiro

    2012-05-01

    Full Text Available Abstract The immunoinhibitory receptor T cell immunoglobulin domain and mucin domain-3 (Tim-3 and its ligand, galectin-9 (Gal-9, are involved in the immune evasion mechanisms for several pathogens causing chronic infections. However, there is no report concerning the role of Tim-3 in diseases of domestic animals. In this study, cDNA encoding for bovine Tim-3 and Gal-9 were cloned and sequenced, and their expression and role in immune reactivation were analyzed in bovine leukemia virus (BLV-infected cattle. Predicted amino acid sequences of Tim-3 and Gal-9 shared high homologies with human and mouse homologues. Functional domains, including tyrosine kinase phosphorylation motif in the intracellular domain of Tim-3 were highly conserved among cattle and other species. Quantitative real-time PCR analysis showed that bovine Tim-3 mRNA is mainly expressed in T cells such as CD4+ and CD8+ cells, while Gal-9 mRNA is mainly expressed in monocyte and T cells. Tim-3 mRNA expression in CD4+ and CD8+ cells was upregulated during disease progression of BLV infection. Interestingly, expression levels for Tim-3 and Gal-9 correlated positively with viral load in infected cattle. Furthermore, Tim-3 expression level closely correlated with up-regulation of IL-10 in infected cattle. The expression of IFN-γ and IL-2 mRNA was upregulated when PBMC from BLV-infected cattle were cultured with Cos-7 cells expressing Tim-3 to inhibit the Tim-3/Gal-9 pathway. Moreover, combined blockade of the Tim-3/Gal-9 and PD-1/PD-L1 pathways significantly promoted IFN-γ mRNA expression compared with blockade of the PD-1/PD-L1 pathway alone. These results suggest that Tim-3 is involved in the suppression of T cell function during BLV infection.

  5. Brown Recluse Spider

    Science.gov (United States)

    ... 6.4-19.1mm) • Color: Golden brown • A dark violin/fiddle shape (see top photo) is located ... Habitat The Brown Recluse Spider builds small retreat webs behind objects of any type. Symptoms • The severity ...

  6. High Tim-3 expression on AML blasts could enhance chemotherapy sensitivity.

    Science.gov (United States)

    Xu, Liangjing; Xu, Jinge; Ma, Shoubao; Li, Xiaoli; Zhu, Mingqing; Chen, Suning; Han, Yue; Tang, Xiaowen; Fu, Zhengzheng; Qiu, Huiying; Yu, Jianhua; Wu, Depei; Wu, Xiaojin

    2017-11-24

    T-cell immunoglobulin and mucin domain-containing molecule3 (Tim-3) represents a novel mechanism of T-cell dysfunction and exhaustion. Tim-3 has also been identified in various solid tumors. However, the role of Tim-3 expression on blast cells in acute myeloid leukemia (AML) is not well understood. In this study, we aimed to explore the role of Tim-3 in patients with de novo AML, and the correlation between Tim-3 and clinicopathological prognosis. The study cohort consisted of 76 patients with de novo non-M3 AML. These patients' bone marrow samples were collected and then bone marrow mononuclear cells (BMCs) were isolated for flow cytometry to detect Tim-3 expression on blasts. According to FAB type, 76 diagnosed AML patients included in this study were: M0 (n=2), M1 (n=16), M2 (n=20), M4 (n=20), M5 (n=16), and M6 (n=2). A positive expression (>20%) of Tim-3 was found in 87% (66/76) of patients with AML. The average percentage of Tim-3(+) blasts in these AML patients was 58.26 ± 29.23%. Moreover, the frequency of Tim-3 high expression was higher in M4 patients than that in other AML patients according to FAB type (P=0.004). Tim-3 high expression was also closely associated with inv(16) (P=0.01) and C/EBPA mutation (P=0.03). The mutations of the following six genes, i.e., FLT3-ITD, NPM1, C-KIT, IDH1/IDH2, DNMT3A, were independent of the Tim-3 expression. Additionally, it is more likely to find higher levels of Tim-3 in the low-risk group than in the intermediate- and high-risk groups (P=0.02). The expression of Tim-3 was positively correlated with CD13 (r=0.36, P=0.001), CD34 (r=0.41, P=0.000), and CD7 (r=0.27, P=0.02) in AML patients. AML patients with high Tim-3 expression achieved significantly high complete remission (CR) rate (P=0.01), while their Tim-3 expression significantly decreased after CR (P=0.01). Blockade of Tim-3 expression on AML blasts significantly reduced the Idarubicin (IDA)-mediated suppression of cell growth and reduction of cell apoptosis in

  7. Prof. Dr. Johannes Christiaan Coetzee as opvoedkundige denker

    Directory of Open Access Journals (Sweden)

    J. J. Snyman

    1953-03-01

    Full Text Available Dit is met genoëe dat ek voldoen aan die versoek om kortliks ’n paar gedagtes uit te spreek oor die opvoedkunde, veral die Calvinistiese opvoedkunde en die opvoedkundige praktyk van prof. Coetzee.

  8. Prof. John Wood, Chief Executive Designate, Dr Gordon Walker, Directorate, Chief Executive, Prof. Ken J. Peach, Head of the Particle Physics Department, CLRC Rutherford Appleton Laboratory, United Kingdom

    CERN Document Server

    Patrice Loïez

    2001-01-01

    L. to. r.: Dr. Ian Wilson, CLIC Deputy Study Leader, Prof. Ken J. Peach, Head of the Particle Physics Department, Prof. John Wood, Chief Executive Designate, Dr. Gordon Walker, Directorate, Chief Executive

  9. [Human brown adipose tissue].

    Science.gov (United States)

    Virtanen, Kirsi A; Nuutila, Pirjo

    2015-01-01

    Adult humans have heat-producing and energy-consuming brown adipose tissue in the clavicular region of the neck. There are two types of brown adipose cells, the so-called classic and beige adipose cells. Brown adipose cells produce heat by means of uncoupler protein 1 (UCP1) from fatty acids and sugar. By applying positron emission tomography (PET) measuring the utilization of sugar, the metabolism of brown fat has been shown to multiply in the cold, presumably influencing energy consumption. Active brown fat is most likely present in young adults, persons of normal weight and women, least likely in obese persons.

  10. TIMS Study, national findings and consequences in Cyprus

    OpenAIRE

    Papanastasiou, Constantinos

    2002-01-01

    The University of Cyprus, as a research institution, has a leading role on local and international research projects. The results for students in mathematics and science of the 4th and 8th grade and in the literacy study (TIMSS) in the final year of secondary school are not encouraging for Cyprus. Cyprus was one of the last among the countries that participated in the TIMS study. But the results for students in mathematics who took advanced courses were very encouraging. Only one country had ...

  11. Cultura digital jovem: as TIMS invadem as periferias, e agora?

    Directory of Open Access Journals (Sweden)

    Márcia Gonçalves Nogueira

    2014-08-01

    Full Text Available Objective of this work is to present a literature review on Young and the Digital Cultural transformations caused by the dissemination of Information Technology and Communication Mobile and wireless (TIMS on the outskirts of the metropolitan area of Recife. To this end, we seek to identify how young periphery, high school students of a public school, they experience the Digital Culture in different social spaces; among them the school, scene of many tensions and generational conflicts and language as social and cultural use of these mobile devices. We highlight some theoretical approaches to the phenomenon of mobile communication and the concept of Digital Culture, adopted in this work. Proposing a reflection on the role of school in the current social context of constant cultural and linguistic transformations multimodality of the digital age. Finally, we present an exercise of looking on Youth Cultures, from different theoretical, to better understand the multiple transits covered by surveyed youth to express themselves and make sense of their audiovisual productions, mediated by TIMS. This theoretical argument was used in the dissertation in mathematics education and technology by one of the authors of this article. Therefore, we hope to contribute to further research on Digital Youth Culture in the context of the periphery.

  12. “This is you”: Encountering Shakespeare with Tim Crouch

    Directory of Open Access Journals (Sweden)

    Sara Soncini

    2017-11-01

    Full Text Available This essay considers Tim Crouch's "I Shakespeare", a suite of monologue plays based on "The Tempest" ("I, Caliban", 2003, "A Midsummer Night's Dream" ("I, Peaseblossom", 2004, "Macbeth" ("I, Banquo", 2005, "Twelfth Night" ("I, Malvolio", 2010 and "Julius Caesar" ("I, Cinna (the poet", 2012. While originally designed for a young audience, Crouch's adaptations have been performed in a variety of theatrical contexts that have added new and probably unforeseen dimensions to their negotiations with Shakespeare. In my analysis I turn to the notion of mobility as a key analytical tool to elucidate the method, aims, as well as the broader cultural meaning of Tim Crouch's reworkings. In his hands, Shakespeare is mobilized as a powerful resource to activate spectators and emphasize their co-authorship in the process of theatre. Through a combination of textual strategies and performance methods, the monologues construct the identities of Shakespeare's characters as multiple and mutable and, in parallel, cast their addressees in fluid, often contradictory roles. My main line of argument is that the plays' propensity of motion is rooted in their emphasis on Shakespeare as a highly mobile cultural signifier which seems confirmed by the monologues' journeys outside the UK. The further adaptational practices triggered by these encounters with foreign audiences are testament to the flexibility of Crouch's dramaturgy of process and its aptitude to accommodate new discursive identities and adjust to each new context of reception.

  13. Sild humanitaar- ja loodusteaduste vahel : intervjuu Aberdeeni ülikooli sotsiaalantropoloogia professori Tim Ingoldiga / Tim Ingold ; interv. Alo Joosepson, Kaie Kotov, Silver Rattasepp, Riste Keskpaik

    Index Scriptorium Estoniae

    Ingold, Tim

    2004-01-01

    4. rahvusvahelise keskkonnaesteetika ja -semiootika konverentsi "Kultuur, loodus, semiootika: kohad" üks peaesineja Tim Ingold tegeleb 1990-ndatest alates antropoloogia ja kunsti suhte uurimisega ning loeb kursust "Antropoloogia, arheoloogia, kunst ja arhitektuur"

  14. Peripheral blood TIM-3 positive NK and CD8+ T cells throughout pregnancy: TIM-3/galectin-9 interaction and its possible role during pregnancy.

    Directory of Open Access Journals (Sweden)

    Matyas Meggyes

    Full Text Available PROBLEM: The T-cell immunoglobulin and mucin domain (TIM family is a relatively newly described group of molecules with a conserved structure and important immunological functions. Identification of Galectin-9 as a ligand for TIM-3 has established the Galectin-9/TIM-3 pathway as an important negative regulator of Th1 immunity and tolerance induction. Data about the TIM-3/Gal-9 pathway in the pathogenesis of human diseases is emerging, but their possible role during human pregnancy is not precisely known. The aim of our study was to investigate the number, phenotype and functional activity of TIM-3+ peripheral blood mononuclear cells during healthy human pregnancy. METHODS OF STUDY: 57 healthy pregnant women [first trimester (n = 16; second trimester (n = 19; third trimester (n = 22] and 30 non-pregnant controls were enrolled in the study. We measured the surface expression of TIM-3 by cytotoxic T cells, NK cells and NK cell subsets as well as Galectin-9 expression by regulatory T cells by flow cytometry. We analyzed the cytokine production and cytotoxicity of TIM3+ and TIM3- CD8 T and NK cells obtained from non-pregnant and healthy pregnant women at different stages of pregnancy by flow cytometry. Serum Galectin-9 levels were measured by ELISA. RESULTS: Our results show that the numbers of peripheral NK and cytotoxic T cells and their TIM-3 expression do not change between the first, second and third trimesters of pregnancy. Compared to non-pregnant individuals, regulatory T cells show higher level of Galectin-9 expression as pregnancy proceeds, which is in line with the level of Galectin-9 in the patients sera. Cytotoxic T cells, NK cells and NK cell subsets expressing TIM-3 molecule show altered cytokine production and cytotoxicity during pregnancy compared to non-pregnant individuals. CONCLUSION: Our results indicate that Galectin-9 expressing regulatory T cells, TIM-3+ cytotoxic T cells and NK cells could play an important role in the

  15. Tim-3: an activation marker and activation limiter of innate immune cells.

    Science.gov (United States)

    Han, Gencheng; Chen, Guojiang; Shen, Beifen; Li, Yan

    2013-12-10

    Tim-3 was initially identified on activated Th1, Th17, and Tc1 cells and induces T cell death or exhaustion after binding to its ligand, Gal-9. The observed relationship between dysregulated Tim-3 expression on T cells and the progression of many clinical diseases has identified this molecule as an important target for intervention in adaptive immunity. Recent data have shown that it also plays critical roles in regulating the activities of macrophages, monocytes, dendritic cells, mast cells, natural killer cells, and endothelial cells. Although the underlying mechanisms remain unclear, dysregulation of Tim-3 expression on these innate immune cells leads to an excessive or inhibited inflammatory response and subsequent autoimmune damage or viral or tumor evasion. In this review, we focus on the expression and function of Tim-3 on innate immune cells and discuss (1) how Tim-3 is expressed and regulated on different innate immune cells; (2) how it affects the activity of different innate immune cells; and (3) how dysregulated Tim-3 expression on innate immune cells affects adaptive immunity and disease progression. Tim-3 is involved in the optimal activation of innate immune cells through its varied expression. A better understanding of the physiopathological role of the Tim-3 pathway in innate immunity will shed new light on the pathogenesis of clinical diseases, such as autoimmune diseases, chronic viral infections, and cancer, and suggest new approaches to intervention.

  16. Dysregulation of TIM-3-galectin-9 pathway in the cystic fibrosis airways.

    LENUS (Irish Health Repository)

    Vega-Carrascal, Isabel

    2011-03-01

    The T-cell Ig and mucin domain-containing molecules (TIMs) have emerged as promising therapeutic targets to correct abnormal immune function in several autoimmune and chronic inflammatory conditions. It has been reported that proinflammatory cytokine dysregulation and neutrophil-dominated inflammation are the main causes of morbidity in cystic fibrosis (CF). However, the role of TIM receptors in CF has not been investigated. In this study, we demonstrated that TIM-3 is constitutively overexpressed in the human CF airway, suggesting a link between CF transmembrane conductance regulator (CFTR) function and TIM-3 expression. Blockade of CFTR function with the CFTR inhibitor-172 induced an upregulation of TIM-3 and its ligand galectin-9 in normal bronchial epithelial cells. We also established that TIM-3 serves as a functional receptor in bronchial epithelial cells, and physiologically relevant concentrations of galectin-9 induced TIM-3 phosphorylation, resulting in increased IL-8 production. In addition, we have demonstrated that both TIM-3 and galectin-9 undergo rapid proteolytic degradation in the CF lung, primarily because of neutrophil elastase and proteinase-3 activity. Our results suggest a novel intrinsic defect that may contribute to the neutrophil-dominated immune response in the CF airways.

  17. Tim-3: An activation marker and activation limiter of innate immune cells

    Directory of Open Access Journals (Sweden)

    Gencheng eHan

    2013-12-01

    Full Text Available Tim-3 was initially identified on activated Th1, Th17, and Tc1 cells and induces T cell death or exhaustion after binding to its ligand, Gal-9. The observed relationship between dysregulated Tim-3 expression on T cells and the progression of many clinical diseases has identified this molecule as an important target for intervention in adaptive immunity. Recent data have shown that it also plays critical roles in regulating the activities of macrophages, monocytes, dendritic cells, mast cells, natural killer cells, and endothelial cells. Although the underlying mechanisms remain unclear, dysregulation of Tim-3 expression on these innate immune cells leads to an excessive or inhibited inflammatory response and subsequent autoimmune damage or viral or tumor evasion. In this review, we focus on the expression and function of Tim-3 on innate immune cells and discuss 1 how Tim-3 is expressed and regulated on different innate immune cells; 2 how it affects the activity of different innate immune cells; and 3 how dysregulated Tim-3 expression on innate immune cells affects adaptive immunity and disease progression. Tim-3 is involved in the optimal activation of innate immune cells through its varied expression. A better understanding of the physiopathological role of the Tim-3 pathway in innate immunity will shed new light on the pathogenesis of clinical diseases, such as autoimmune diseases, chronic viral infections, and cancer, and suggest new approaches to intervention.

  18. Dysregulation of TIM-3-galectin-9 pathway in the cystic fibrosis airways.

    LENUS (Irish Health Repository)

    Vega-Carrascal, Isabel

    2012-02-01

    The T-cell Ig and mucin domain-containing molecules (TIMs) have emerged as promising therapeutic targets to correct abnormal immune function in several autoimmune and chronic inflammatory conditions. It has been reported that proinflammatory cytokine dysregulation and neutrophil-dominated inflammation are the main causes of morbidity in cystic fibrosis (CF). However, the role of TIM receptors in CF has not been investigated. In this study, we demonstrated that TIM-3 is constitutively overexpressed in the human CF airway, suggesting a link between CF transmembrane conductance regulator (CFTR) function and TIM-3 expression. Blockade of CFTR function with the CFTR inhibitor-172 induced an upregulation of TIM-3 and its ligand galectin-9 in normal bronchial epithelial cells. We also established that TIM-3 serves as a functional receptor in bronchial epithelial cells, and physiologically relevant concentrations of galectin-9 induced TIM-3 phosphorylation, resulting in increased IL-8 production. In addition, we have demonstrated that both TIM-3 and galectin-9 undergo rapid proteolytic degradation in the CF lung, primarily because of neutrophil elastase and proteinase-3 activity. Our results suggest a novel intrinsic defect that may contribute to the neutrophil-dominated immune response in the CF airways.

  19. Brown recluse spider envenomation.

    Science.gov (United States)

    Furbee, R Brent; Kao, Louise W; Ibrahim, Danyal

    2006-03-01

    Brown recluse spider bite is a common diagnosis in almost every state in America. In fact, cases have been reported in areas where the spider has never been seen. A review of medical literature reveals that most current concepts regarding brown recluse spider envenomation are based on supposition. In this article, we attempt to review critically our present understanding of brown recluse bites with a focus on the published evidence.

  20. Brown Fat Cell Isolation

    OpenAIRE

    sprotocols

    2014-01-01

    Author: C.R. Kahn ### 1.) ISOLATION AND PRIMARY CULTURE OF BROWN FAT PREADIPOCYTES ### Rationale: To prepare primary brown preadipocytes for immortalization: useful for metabolic studies from knockout mice. This consists of the following five protocols. References: Fasshauer, M., J. Klein, K M. Kriauciunas, K. Ueki, M.Benito, and C.R. Kahn. 2001. Essential role of insulin substrate 1 in differentiation of brown adipocytes. *Mol Cell Biol* 21: 319-329. Fasshauer, M....

  1. Plasmodesmata of brown algae

    OpenAIRE

    Terauchi, Makoto; Nagasato, Chikako; Motomura, Taizo

    2014-01-01

    Plasmodesmata (PD) are intercellular connections in plants which play roles in various developmental processes. They are also found in brown algae, a group of eukaryotes possessing complex multicellularity, as well as green plants. Recently, we conducted an ultrastructural study of PD in several species of brown algae. PD in brown algae are commonly straight plasma membrane-lined channels with a diameter of 10?20?nm and they lack desmotubule in contrast to green plants. Moreover, branched PD ...

  2. Multicollector ICPMS and TIMS as tools for isotopic fingerprinting

    Science.gov (United States)

    Bouman, C.; Schwieters, J. B.; Lloyd, N. S.; Trinquier, A.

    2012-04-01

    Elements such as C, N, O and S are essential for chemical and biological processes in nature and very small shifts in the isotopic composition of these elements are important tracers to explore complex processes in nature. During the last few years, stable isotopes of elements as Cl, Ca, Fe, Cu, Zn, Sr, Hg and Pb are getting more and more attention as tracer to study biomedical and environmental processes, as well as forensics and archaeometry. Multi-collector ICPMS and TIMS enable high-precision isotopic analysis of these so-called non-traditional stable isotope systems. MC-ICPMS is a powerful technique for the isotopic analysis of most elements, with the exception of light elements such as H, C, N and O and the noble gases. Various inlet systems can be used to introduce samples into the mass spectrometer, for instance gas chromatography (GC), liquid chromatography (LC) ) for compound-specific isotope analysis, laser ablation for direct analysis of solids, or conventional liquid nebulization for liquid samples. The aerosol is transported by an Ar and/or He gas flow into the ICP source where it is effectively ionized and introduced into the mass analyzer through a differential pumping system. Molecular interferences as carbides, nitrides, oxides, argides or doubly-charged species can show up in the mass spectrum and interfere with the elemental isotope peaks. High mass resolution is needed to effectively discriminate against these interferences. The NEPTUNE Plus is specially designed to meet this requirement and expand the power of isotope ratio measurements even to elements where previously isobaric interferences were the limit. For some specific isotope systems, such as Ca, Sr and Pb, the thermal ionization technique may have advantages, due to the potentially lower backgrounds and higher sensitivity. Prior to the TIMS analysis, the sample is chemically purified, loaded on a filament and introduced into the mass spectrometer. With the introduction of the TRITON

  3. In-Flight Wavelength Calibration of Thermal Infrared Multispectral Scanner (TIMS) Data Acquired from the ER-2

    Science.gov (United States)

    Hook, S.; Okada, K.

    1994-01-01

    In 1991 one flightline of Thermal Infrared Multispectral Scanner (TIMS) data was acquired over Castaic Lake, California and in 1992 four flightlines of TIMS data were acquired over Death Valley, California.

  4. Evaluation of two dynamic in vitro models simulating fasted and fed state conditions in the upper gastrointestinal tract (TIM-1 and tiny-TIM) for investigating the bioaccessibility of pharmaceutical compounds from oral dosage forms

    NARCIS (Netherlands)

    Verwei, M.; Minekus, M.; Zeijdner, E.; Schilderink, R.; Havenaar, R.

    2016-01-01

    Pharmaceutical research needs predictive in vitro tools for API bioavailability in humans. We evaluated two dynamic in vitro gastrointestinal models: TIM-1 and tiny-TIM. Four low-soluble APIs in various formulations were investigated in the TIM systems under fasted and fed conditions. API

  5. In Memoriam: Prof. Dr Dragutin Djurovic (1937-2013)

    Science.gov (United States)

    2013-12-01

    Prof. dr Dragutin Djurovic was born in Guca, Serbia, on December 20, 1937. He completed his primary and secondary education in Guca and Cacak. In the period 1956-1958, he studied at the General Military Academy in Belgrade. He enrolled at the Faculty of Sciences and Mathematics - Astronomy Group in 1958 and graduated in 1963. After graduation he went to study visits to Paris (1966) and Bruxelles (1972 and 1975). He obtained his MSc degree in 1970 from the University of Belgrade with a thesis entitled "Application of different types of telescopes for astronomical determination of time". His supervisor for the master thesis was Prof. Zaharije Brkic. Dragutin Djurovic defended his PhD thesis "Contribution to determination of Earth-rotation variations and polar motion" at the University of Belgrade in 1974. Most of the thesis-related research was done in Bruxelles during 1972 under the supervision of Prof. Paul Melchior.

  6. U-series dating using thermal ionisation mass spectrometry (TIMS)

    Energy Technology Data Exchange (ETDEWEB)

    McCulloch, M.T. [Australian National University, Canberra, ACT (Australia). Research School of Earth Science

    1999-11-01

    U-series dating is based on the decay of the two long-lived isotopes{sup 238}U({tau}{sub 1/2}=4.47 x 10{sup 9} years) and {sup 235}U ({tau}{sub 1/2} 0.7 x 10{sup 9} years). {sup 238}U and its intermediate daughter isotopes {sup 234}U ({tau}{sub 1/2} = 245.4 ka) and {sup 230}Th ({tau}{sub 1/2} = 75.4 ka) have been the main focus of recently developed mass spectrometric techniques (Edwards et al., 1987) while the other less frequently used decay chain is based on the decay {sup 235}U to {sup 231}Pa ({tau}{sub 1/2} = 32.8 ka). Both the {sup 238}U and {sup 235}U decay chains terminate at the stable isotopes {sup 206}Pb and {sup 207}Pb respectively. Thermal ionization mass spectrometry (TIMS) has a number of inherent advantages, mainly the ability to measure isotopic ratios at high precision on relatively small samples. In spite of these now obvious advantages, it is only since the mid-1980`s when Chen et al., (1986) made the first precise measurements of {sup 234}U and {sup 232}Th in seawater followed by Edwards et al., (1987) who made combined {sup 234}U-{sup 230}Th measurements, was the full potential of mass spectrometric methods first realised. Several examples are given to illustrate various aspects of TIMS U-series 9 refs., 3 figs.

  7. Father Brown, Selected sories

    NARCIS (Netherlands)

    Chesterton, G.K.

    2005-01-01

    Father Brown, a small, round Catholic priest with a remarkable understanding of the criminal mind, is one of literature's most unusual and endearing detectives, able to solve the strangest crimes in a most fascinating manner. This collection draws from all five Father Brown books, and within their

  8. Brown adipocyte function

    DEFF Research Database (Denmark)

    Winther, Sally

    . The first part of this thesis explores this by identifying and investigating two novel kinase regulators of brown adipocyte function. Study 1 demonstrates that spleen tyrosine kinase is a hitherto undescribed regulator of brown adipocyte differentiation and activation. Study 2 identifies glycogen synthase...... kinase 3 as a negative regulator of the canonical p38 mitogen-activated protein kinase signaling cascade. Thus both studies add novel regulatory layers to the growing understanding of brown adipocyte signal transduction. Activated BAT also exerts great influence on whole body glucose homeostasis......, of great interest for diabetes treatment. The second part of this thesis explores this by investigating glycolytic flux in activated brown adipocytes. Study 3 identifies hypoxia-inducible factor 1α as an important regulator of glycolytic gene expression in brown adipocytes. Study 4 establishes...

  9. Curriculum Vitae of Prof. Dr. Gürer GÜLSEVİN and Prof. Dr. Ayşe İLKER’s Impressions About Him Prof. Dr. Gürer GÜLSEVİN’in Özgeçmişi ve Prof. Dr. Ayşe İLKER’in Onun Hakkındaki İzlenimleri

    Directory of Open Access Journals (Sweden)

    Özgür AY

    2011-01-01

    Full Text Available Curriculum Vitae of Prof. Dr. Gürer GÜLSEVİN and Prof. Dr. Ayşe İLKER’s Impressions About Him Prof. Dr. Gürer GÜLSEVİN’in Özgeçmişi ve Prof. Dr. Ayşe İLKER’in Onun Hakkındaki İzlenimleri

  10. Airborne Thermal Infrared Multispectral Scanner (TIMS) images over disseminated gold deposits, Osgood Mountains, Humboldt County, Nevada

    Science.gov (United States)

    Krohn, M. Dennis

    1986-01-01

    The U.S. Geological Survey (USGS) acquired airborne Thermal Infrared Multispectral Scanner (TIMS) images over several disseminated gold deposits in northern Nevada in 1983. The aerial surveys were flown to determine whether TIMS data could depict jasperoids (siliceous replacement bodies) associated with the gold deposits. The TIMS data were collected over the Pinson and Getchell Mines in the Osgood Mountains, the Carlin, Maggie Creek, Bootstrap, and other mines in the Tuscarora Mountains, and the Jerritt Canyon Mine in the Independence Mountains. The TIMS data seem to be a useful supplement to conventional geochemical exploration for disseminated gold deposits in the western United States. Siliceous outcrops are readily separable in the TIMS image from other types of host rocks. Different forms of silicification are not readily separable, yet, due to limitations of spatial resolution and spectral dynamic range. Features associated with the disseminated gold deposits, such as the large intrusive bodies and fault structures, are also resolvable on TIMS data. Inclusion of high-resolution thermal inertia data would be a useful supplement to the TIMS data.

  11. Traditional Indian medicine (TIM) and traditional Korean medicine (TKM): aconstitutional-based concept and comparison.

    Science.gov (United States)

    Kang, Young Min; Komakech, Richard; Karigar, Chandrakant Shivappa; Saqib, Asma

    2017-06-01

    Traditional and complementary medicine (T&CM) plays an integral role in providing health care worldwide. It is based on sound fundamental principles and centuries of practices. This study compared traditional Indian medicine (TIM) and traditional Korean medicine (TKM) basing on data obtained from peer reviewed articles, respective government institutional reports and World Health Organization reports. Despite the fact that TIM and TKM have individual qualities that are unique from each other including different histories of origin, they share a lot in common. Apart from Homeopathy in TIM, both systems are hinged on similar principle of body constitutional-based concept and similar disease diagnosis methods of mainly auscultation, palpation, visual inspection, and interrogation. Similarly, the treatment methods of TIM and TKM follow similar patterns involving use of medicinal herbs, moxibustion, acupuncture, cupping, and manual therapy. Both T&CM are majorly practiced in well-established hospitals by T&CM doctors who have undergone an average of 6-7 years of specialized trainings. However, unlike TIM which has less insurance coverage, the popularity of TKM is majorly due to its wide national insurance coverage. These two medical traditions occupy increasingly greater portion of the global market. However, TIM especially Ayurveda has gained more global recognition than TKM although the emergence of Sasang Constitutional Medicine in TKM is beginning to become more popular. This comparative analysis between TIM and TKM may provide vital and insightful contribution towards constitutional-based concept for further development and future studies in T&CM.

  12. Traditional Indian medicine (TIM and traditional Korean medicine (TKM: aconstitutional-based concept and comparison

    Directory of Open Access Journals (Sweden)

    Young Min Kang

    2017-06-01

    Full Text Available Traditional and complementary medicine (T&CM plays an integral role in providing health care worldwide. It is based on sound fundamental principles and centuries of practices. This study compared traditional Indian medicine (TIM and traditional Korean medicine (TKM basing on data obtained from peer reviewed articles, respective government institutional reports and World Health Organization reports. Despite the fact that TIM and TKM have individual qualities that are unique from each other including different histories of origin, they share a lot in common. Apart from Homeopathy in TIM, both systems are hinged on similar principle of body constitutional-based concept and similar disease diagnosis methods of mainly auscultation, palpation, visual inspection, and interrogation. Similarly, the treatment methods of TIM and TKM follow similar patterns involving use of medicinal herbs, moxibustion, acupuncture, cupping, and manual therapy. Both T&CM are majorly practiced in well-established hospitals by T&CM doctors who have undergone an average of 6–7 years of specialized trainings. However, unlike TIM which has less insurance coverage, the popularity of TKM is majorly due to its wide national insurance coverage. These two medical traditions occupy increasingly greater portion of the global market. However, TIM especially Ayurveda has gained more global recognition than TKM although the emergence of Sasang Constitutional Medicine in TKM is beginning to become more popular. This comparative analysis between TIM and TKM may provide vital and insightful contribution towards constitutional-based concept for further development and future studies in T&CM.

  13. The TIM-3 pathway ameliorates Theiler's murine encephalomyelitis virus-induced demyelinating disease.

    Science.gov (United States)

    Kaneyama, Tomoki; Tomiki, Hiroki; Tsugane, Sayaka; Inaba, Yuji; Ichikawa, Motoki; Akiba, Hisaya; Yagita, Hideo; Kim, Byung S; Koh, Chang-Sung

    2014-07-01

    Infection by Theiler's murine encephalomyelitis virus (TMEV) in the central nervous system (CNS) induces an immune-mediated demyelinating disease in susceptible mouse strains and serves as a relevant infection model for human multiple sclerosis. T-cell immunoglobulin and mucin domain-3 (TIM-3) has been demonstrated to play a crucial role in the maintenance of peripheral tolerance. In this study, we examined the regulatory role of the TIM-3 pathway in the development of TMEV-induced demyelinating disease (TMEV-IDD). The expression of TIM-3 was increased at both protein and mRNA levels in the spinal cords of mice with TMEV-IDD compared with naive controls. In addition, by utilizing a blocking mAb, we demonstrate that TIM-3 negatively regulates TMEV-specific ex vivo production of IFN-γ and IL-10 by CD4(+) T cells and IFN-γ by CD8(+) T cells from the CNS of mice with TMEV-IDD at 36 days post-infection (dpi). In vivo blockade of TIM-3 by using the anti-TIM-3 mAb resulted in significant exacerbation of the development of TMEV-IDD both clinically and histologically. The number of infiltrating mononuclear cells in the CNS was also increased in mice administered with anti-TIM-3 mAb both at the induction phase (10 dpi) and at the effector phase (36 dpi). Flow cytometric analysis of intracellular cytokines revealed that the number of CD4(+) T cells producing TNF, IL-4, IL-10 and IL-17 was significantly increased at the effector phase in the CNS of anti-TIM-3 mAb-treated mice. These results suggest that the TIM-3 pathway plays a critical role in the regulation of TMEV-IDD. © The Japanese Society for Immunology. 2014. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  14. Ueber die von Prof. Dr. A. Gerstaecker beschriebenen Ascalaphidae (Neuroptera)

    NARCIS (Netherlands)

    Weele, van der H.W.

    1906-01-01

    In den Mitth. des naturw. Ver. für Neuvorpomm. und Rügen, Band XVI, XIX, XX. und XXV, hat Gerstaecker eine Reihe neuer Arten Planipennia beschrieben, von welchen ich durch die Freundlichkeit seines Nachfolgers Prof. G. W. Müller in Greifswald die Ascalaphiden zur Untersuchung bekommen habe. Obschon

  15. Editorial Prof Lundgren's significant contribution to SAJAA and its ...

    African Journals Online (AJOL)

    Prof Chris Lundgren was the Editor-in-Chief of the Southern. African Journal of Anaesthesia and Analgesia (SAJAA) for a remarkable 14 years from 2001-2015. Under her excellent guidance, the journal has developed and grown to the point that the Academy of Science for South Africa's (ASSAf) review of scholarly ...

  16. Prof. Dr. A. J. H. van der Walt

    Directory of Open Access Journals (Sweden)

    J. C. Coetzee

    1956-03-01

    Full Text Available Prof. Van der Walt, die eerste prinsipaal van die Universiteit van Suid-Afrika en vroeër ook die eerste professor in die Geskiedenis aan die Potchefstroomse Universiteitskollege vir Christelike Hoër Onderwys, tree op 31 Maart 1956 uit die aktiewe universitêre diens.

  17. Itinerary for Prof. Nitash Balsara Arrival in Mumbai, November 4 ...

    Indian Academy of Sciences (India)

    RV

    2014-11-11

    Arrival in Mumbai, November 4. November 4-10 in and around Mumbai, will give lecture in IIT Bombay. November 11-15, in and around Kanpur, Prof Ashutosh Sharma will organize program. November 11, 2014. Mumbai-Lucknow: Air India AI-625; departs 10:30, reaches. 12:40. November 15, 2014. Lucknow-Bangalore.

  18. Prognostic value of PD-1 and TIM-3 on CD3+ T cells from diffuse large B-cell lymphoma.

    Science.gov (United States)

    Zhang, Li; Du, Hui; Xiao, Tai-wu; Liu, Ji-zhu; Liu, Guo-zhen; Wang, Jing-xia; Li, Guang-yao; Wang, Le-xin

    2015-10-01

    To investigate the expression of PD-1 and TIM-3 in CD3+ T cells in patients with diffuse large B-cell lymphoma (DLBCL). A retrospective analysis was conducted on data from 46 patients with newly diagnosed DLBCL and 30 healthy people. Flow cytometry was used to detect the expression of PD-1 and TIM-3 before and after chemotherapy. Compared to healthy control, the expression of PD-1 and TIM-3 in patients with DLBCL was increased in CD3+ T cells. There is no significant change of PD-1 and TIM-3 in patients with stage I/II DLBCL, however, they were markedly increased in patients with stage III/IV DLBCL. The expression of PD-1 and TIM-3 elevated in DLBCL patients with B symptoms, IPI score >2 points and high level of LDH and Ki-67. After four courses of standard chemotherapy, PD-1 and TIM-3 expression level decreased. The treatment efficiency is higher in patients with low expression of PD-1 and TIM-3 than in patients with high PD-1 and TIM-3 expression. DLBCL patients have high expression level of PD-1 and TIM-3, which are related to DLBCL staging. PD-1 and TIM-3 expression levels are also related to the efficiency of chemotherapy. PD-1 and TIM-3 expression levels may be used as an indicator of chemotherapeutic efficacy in patients with DLBCL. Copyright © 2015. Published by Elsevier Masson SAS.

  19. Sensor 17 Thermal Isolation Mounting Structure (TIMS) Design Improvements

    Energy Technology Data Exchange (ETDEWEB)

    Enstrom, K. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-09-04

    The SENSOR 17 thermographic camera weighs approximately 0.5lbs, has a fundamental mode of 167 Hz, and experiences 0.75W of heat leakage in through the TIMS. The configuration, shown in Figure 1, is comprised of four 300 Series SST washers paired in tandem with P.E.I (Ultem 100) washers. The SENSOR 17 sensor is mounted to a 300 series stainless plate with A-shaped arms. The Plate can be assumed to be at ambient temperatures (≈293K) and the I.R. Mount needs to be cooled to 45K. It is attached to the tip of a cryocooler by a ‘cold strap’ and is assumed to be at the temperature of the cold-strap (≈45K). During flights SENSOR 17 experiences excitations at frequencies centered around 10-30Hz, 60Hz, and 120Hz from the aircraft flight environment. The temporal progression described below depicts the 1st Modal shape at the systems resonant frequency. This simulation indicates Modal articulation will cause a pitch rate of the camera with respect to the body axis of the airplane. This articulation shows up as flutter in the camera.

  20. Peripheral blood TIM-3 positive NK and CD8+ T cells throughout pregnancy

    DEFF Research Database (Denmark)

    Meggyes, Matyas; Miko, Eva; Polgar, Beata

    2014-01-01

    negative regulator of Th1 immunity and tolerance induction. Data about the TIM-3/Gal-9 pathway in the pathogenesis of human diseases is emerging, but their possible role during human pregnancy is not precisely known. The aim of our study was to investigate the number, phenotype and functional activity...... by cytotoxic T cells, NK cells and NK cell subsets as well as Galectin-9 expression by regulatory T cells by flow cytometry. We analyzed the cytokine production and cytotoxicity of TIM3+ and TIM3- CD8 T and NK cells obtained from non-pregnant and healthy pregnant women at different stages of pregnancy by flow...... cytometry. Serum Galectin-9 levels were measured by ELISA. RESULTS: Our results show that the numbers of peripheral NK and cytotoxic T cells and their TIM-3 expression do not change between the first, second and third trimesters of pregnancy. Compared to non-pregnant individuals, regulatory T cells show...

  1. Kontrol Optimal pada Model Economic Order Quantity (EOQ dengan Inisiatif Tim Penjualan

    Directory of Open Access Journals (Sweden)

    Abdul Latif Al Fauzi

    2017-06-01

    Full Text Available Pengendalian  tingkat persediaan stok suatu produk/barang merupakan salah satu kegiatan yang penting dalam kelancaran penjualan, yang juga berakibat pada keuntungan yang akan diperoleh dari penjualan suatu produk/barang.  Model Economic Order Quantity (EOQ merupakan salah satu model persediaan barang yang sering digunakan untuk pengendalian persedian barang. Pada artikel ini dibahas kontrol optimal pada model EOQ dengan inisiatif tim penjualan tidak hanya pada saat kondisi setimbang saja, tetapi kontrol optimal dengan usaha tim penjualan pada setiap saat. Strategi kontrol optimal dilakukan dengan meminimumkan biaya persediaan, biaya pembelian, biaya penjualan dan biaya usaha tim penjualan. Masalah kontrol optimal diselesaikan menggunakan prinsip maksimum Pontryagin. Solusi optimal yang diperoleh disimulasikan secara numerik menggunakan metode Sweep Maju-Mundur. Berdasarkan hasil simulasi numerik dapat diketahui bahwa semakin besar koefisien tingkat permintaan barang, maka proses persediaan barang akan lebih cepat berkurang. Selain itu semakin besar usaha tim penjualan, maka proses persediaan barang akan lebih sedikit bahkan lebih cepat habis.

  2. Tim-3 blocking rescue macrophage and T cell function against Mycobacterium tuberculosis infection in HIV+ patients

    Directory of Open Access Journals (Sweden)

    Isabel Sada-Ovalle

    2015-10-01

    Full Text Available Introduction: T cell immunoglobulin and mucin domain (Tim 3 and programmed death 1 (PD-1 are co-inhibitory receptors involved in the so-called T cell exhaustion, and in vivo blockade of these molecules restores T cell dysfunction. High expression of Tim-3 and PD-1 is induced after chronic antigen-specific stimulation of T cells during HIV infection. We have previously demonstrated that the interaction of Tim-3 with its ligand galectin-9 induces macrophage activation and killing of Mycobacterium tuberculosis. Our aim in this study was to analyze the Tim-3 expression profile before and after six months of antiretroviral therapy and the impact of Tim-3 and PD-1 blocking on immunity against M. tuberculosis. Materials and methods: HIV+ patients naïve to anti-retroviral therapy (ART were followed up for six months. Peripheral immune-cell phenotype (CD38/HLA-DR/galectin-9/Tim-3 and PD-1 was assessed by flow cytometry. Supernatants were analyzed with a multiplex cytokine detection system (human Th1/Th2 cytokine Cytometric Bead Array by flow cytometry. Control of bacterial growth was evaluated by using an in vitro experimental model in which virulent M. tuberculosis-infected macrophages were cultured with T cells in the presence or absence of Tim-3 and PD-1 blocking antibodies. Interleukin-1 beta treatment of infected macrophages was evaluated by enumerating colony-forming units. Results: We showed that HIV+ patients had an increased expression of Tim-3 in T cells and were able to control bacterial growth before ART administration. By blocking Tim-3 and PD-1, macrophages and T cells recovered their functionality and had a higher ability to control bacterial growth; this result was partially dependent on the restitution of cytokine production. Conclusions: In this study, we demonstrated that increased Tim-3 expression can limit the ability of the immune system to control the infection of intracellular bacteria such as M. tuberculosis. The use of ART and

  3. Plasmodesmata of brown algae.

    Science.gov (United States)

    Terauchi, Makoto; Nagasato, Chikako; Motomura, Taizo

    2015-01-01

    Plasmodesmata (PD) are intercellular connections in plants which play roles in various developmental processes. They are also found in brown algae, a group of eukaryotes possessing complex multicellularity, as well as green plants. Recently, we conducted an ultrastructural study of PD in several species of brown algae. PD in brown algae are commonly straight plasma membrane-lined channels with a diameter of 10-20 nm and they lack desmotubule in contrast to green plants. Moreover, branched PD could not be observed in brown algae. In the brown alga, Dictyota dichotoma, PD are produced during cytokinesis through the formation of their precursor structures (pre-plasmodesmata, PPD). Clustering of PD in a structure termed "pit field" was recognized in several species having a complex multicellular thallus structure but not in those having uniseriate filamentous or multiseriate one. The pit fields might control cell-to-cell communication and contribute to the establishment of the complex multicellular thallus. In this review, we discuss fundamental morphological aspects of brown algal PD and present questions that remain open.

  4. TIM-1 attenuates the protection of ischemic preconditioning for ischemia reperfusion injury in liver transplantation.

    Science.gov (United States)

    Zhang, Yu; Liu, Yuanxing; Chen, Hui; Zheng, Xiaoxiao; Xie, Shangzhi; Chen, Wei; Ji, Haofeng; Zheng, Shusen

    2017-01-01

    Ischemic preconditioning (IPC) has been introduced to protect grafts against ischemic reperfusion injury (IRI) during liver transplantation (LT) in recent years. However, the underlying molecular mechanisms of IPC are not fully understood. We aimed to confirm whether the efficacy of IPC is dependent on T cell Immunoglobulin and Mucin domain-containing molecules-1 (TIM-1). Quantitative real-time reverse transcription PCR and western blotting were used to detect the expression of genes of interest. Graft function was assessed using the levels of alanine transaminase (ALT) and aspartate transaminase (AST), percentage of apoptosis cells and pathological examination. IPC treatment alleviated graft function after ischemic reperfusion. AST, ALT, CD68, CD3 positive cells and tissue myeloperoxidase activity were decreased significantly by IPC. IPC decreased the expressions of the cytokines and chemokines. Compared with the IRI group, TIM-1 expression and TIM-1 positive cells were inhibited significantly in the IPC group. TIM-1 blockage abolished the protective effect of IPC on IRI damage. IPC could not further improve graft function and decrease the sequestration of immune cells after blocking TIM-1 signaling. IPC is a convenient therapeutic strategy against IRI during LT. The benefit of IPC depends on TIM-1 signaling.

  5. TIM-1 attenuates the protection of ischemic preconditioning for ischemia reperfusion injury in liver transplantation

    Science.gov (United States)

    Zhang, Yu; Liu, Yuanxing; Chen, Hui; Zheng, Xiaoxiao; Xie, Shangzhi; Chen, Wei; Ji, Haofeng; Zheng, Shusen

    2017-01-01

    Ischemic preconditioning (IPC) has been introduced to protect grafts against ischemic reperfusion injury (IRI) during liver transplantation (LT) in recent years. However, the underlying molecular mechanisms of IPC are not fully understood. We aimed to confirm whether the efficacy of IPC is dependent on T cell Immunoglobulin and Mucin domain-containing molecules-1 (TIM-1). Quantitative real-time reverse transcription PCR and western blotting were used to detect the expression of genes of interest. Graft function was assessed using the levels of alanine transaminase (ALT) and aspartate transaminase (AST), percentage of apoptosis cells and pathological examination. IPC treatment alleviated graft function after ischemic reperfusion. AST, ALT, CD68, CD3 positive cells and tissue myeloperoxidase activity were decreased significantly by IPC. IPC decreased the expressions of the cytokines and chemokines. Compared with the IRI group, TIM-1 expression and TIM-1 positive cells were inhibited significantly in the IPC group. TIM-1 blockage abolished the protective effect of IPC on IRI damage. IPC could not further improve graft function and decrease the sequestration of immune cells after blocking TIM-1 signaling. IPC is a convenient therapeutic strategy against IRI during LT. The benefit of IPC depends on TIM-1 signaling. PMID:28861157

  6. [MRI in congenital Brown's syndrome: report of 16 cases].

    Science.gov (United States)

    Cousin, M; Girard, N; Denis, D

    2013-03-01

    Superior oblique retraction syndrome or Brown's syndrome is one of the so-called restrictive syndromes causing anatomic strabismus. It is characterized by active and passive limitation of upward gaze in adduction in the field of action of the superior oblique muscle (SO). The etiology of this congenital syndrome remains unknown. The purpose of this prospective study is to analyze brain and orbital magnetic resonance imaging (MRI) in patients with congenital Brown's syndrome. Sixteen children (19 months - 9 years) underwent complete ophthalmologic evaluation followed by brain/orbital MRI with attention to the superior oblique muscle. Average age at time of MRI was 4.2 years old. Among patients included were eight girls and eight boys. MRI was performed on a 1.5T (Symphony TIM, Siemens, Erlangen) to visualize the orbit and specifically the SO. Of 16 eyes, 13 demonstrated radiologic abnormalities of the SO muscle; six demonstrated tendon-trochlea complex hypertrophy, four demonstrated complete SO hypertrophy (tendon-trochlea-muscle belly), one demonstrated trochlear hypertrophy, and two demonstrated abnormalities solely of the tendons, of which one was longer and one was thinner with fibrosis. MRI shows a high frequency of SO radiologic abnormalities in congenital Brown's syndrome. MRI permits the analysis of not only the tendon, but also the trochlea and muscle belly, whereas surgery only allows visualization of the tendon. MRI proved to be an interesting tool for investigation of these patients and for a better understanding of the pathogenesis. Copyright © 2012. Published by Elsevier Masson SAS.

  7. Downregulation of TIM-3 mRNA expression in peripheral blood mononuclear cells from patients with systemic lupus erythematosus

    Energy Technology Data Exchange (ETDEWEB)

    Cai, X.Z. [Central Laboratory, First Affiliated Hospital, China Medical University, Shenyang (China); Department of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang (China); Huang, W.Y.; Qiao, Y.; Chen, Y.; Du, S.Y.; Chen, D.; Yu, S. [Central Laboratory, First Affiliated Hospital, China Medical University, Shenyang (China); Liu, N. [Department of Nephrology, First Affiliated Hospital, China Medical University, Shenyang (China); Dou, L.Y. [Central Laboratory, First Affiliated Hospital, China Medical University, Shenyang (China); Jiang, Y. [Central Laboratory, First Affiliated Hospital, China Medical University, Shenyang (China); Department of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang (China); Department of Dermatology, First Affiliated Hospital, China Medical University, Shenyang (China)

    2014-10-17

    The T-cell immunoglobulin and mucin domain (TIM) family is associated with autoimmune diseases, but its expression level in the immune cells of systemic lupus erythematosus (SLE) patients is not known. The aim of this study was to investigate whether the expression of TIM-3 mRNA is associated with pathogenesis of SLE. Quantitative real-time reverse transcription-polymerase chain reaction analysis (qRT-PCR) was used to determine TIM-1, TIM-3, and TIM-4 mRNA expression in peripheral blood mononuclear cells (PBMCs) from 132 patients with SLE and 62 healthy controls. The PBMC surface protein expression of TIMs in PBMCs from 20 SLE patients and 15 healthy controls was assayed by flow cytometry. Only TIM-3 mRNA expression decreased significantly in SLE patients compared with healthy controls (P<0.001). No significant differences in TIM family protein expression were observed in leukocytes from SLE patients and healthy controls (P>0.05). SLE patients with lupus nephritis (LN) had a significantly lower expression of TIM-3 mRNA than those without LN (P=0.001). There was no significant difference in the expression of TIM-3 mRNA within different classes of LN (P>0.05). Correlation of TIM-3 mRNA expression with serum IgA was highly significant (r=0.425, P=0.004), but was weakly correlated with total serum protein (r{sub s}=0.283, P=0.049) and serum albumin (r{sub s}=0.297, P=0.047). TIM-3 mRNA expression was weakly correlated with the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI; r{sub s}=-0.272, P=0.032). Our results suggest that below-normal expression of TIM-3 mRNA in PBMC may be involved in the pathogenesis of SLE.

  8. How, Now, Brown Dwarfs?

    Science.gov (United States)

    Brecher, Kenneth

    2009-01-01

    The vocabulary of astronomy is riddled with colorful names for stars, from red giants to blue stragglers. Objects with masses between roughly .01 and .1 solar masses are called "brown dwarfs". Do they - could they - ever actually appear brown? Color is not a one-dimensional physical parameter like wavelength. It is a complex, psychophysical phenomenon involving not only three degrees of freedom - hue (often incorrectly equated with "color"), saturation and brightness - but also observational context. The perceptual nature of color has been known since Newton wrote in his "Opticks” in 1704: "For the Rays to speak properly are not coloured. In them there is nothing else than a certain Power and disposition to stir up a Sensation of this or that Colour.” To most observers, the 2000 or so naked eye stars observable from the northern hemisphere all appear white, with the half dozen exceptions which look reddish/orange like Betelgeuse, Arcturus and Antares. But what color would Betelgeuse (effective temperature 3600 K) appear at a distance of, say, 100 times the Earth-Sun separation? Not red. In fact, it has a temperature about 40% higher than that of an ordinary incandescent light bulb. It would appear white (or yellowish)! Can a very cool radiating (emissive) object ever appear brown? What is brown anyway? It is not a primary or even secondary color. In this presentation, we will explore the nature and meaning of "brown” by the use of several physical and computer demonstrations developed as part of "Project LITE- Light Inquiry Through Experiments", an educational materials development project. These demonstrations show that an isolated thermally radiating object will never appear brown. Hence the term "Brown Dwarf” is as nonsensical as the phrase "How, Now, Brown Cow?". Project LITE is supported by the NSF through DUE Grant # 0715975.

  9. Prof. Nanopoulos visits Hill Primary School in Greece

    CERN Multimedia

    2014-01-01

    This video is an extract of a reportage broadcasted by SKAI TV in Greece about the visit of Prof. Dimitri Nanopoulos to Hill Primary School, the oldest operating school in Greece. The video describes a breakthrough education programme aimed at introducing big ideas in physics, particle physics and cosmology to K-6 students through a pedagogical approach that promotes inquiry, creativity and hands-on experimentation with the use everyday materials.

  10. Age-related expansion of Tim-3 expressing T cells in vertically HIV-1 infected children.

    Directory of Open Access Journals (Sweden)

    Ravi Tandon

    Full Text Available As perinatally HIV-1-infected children grow into adolescents and young adults, they are increasingly burdened with the long-term consequences of chronic HIV-1 infection, with long-term morbidity due to inadequate immunity. In progressive HIV-1 infection in horizontally infected adults, inflammation, T cell activation, and perturbed T cell differentiation lead to an "immune exhaustion", with decline in T cell effector functions. T effector cells develop an increased expression of CD57 and loss of CD28, with an increase in co-inhibitory receptors such as PD-1 and Tim-3. Very little is known about HIV-1 induced T cell dysfunction in vertical infection. In two perinatally antiretroviral drug treated HIV-1-infected groups with median ages of 11.2 yr and 18.5 yr, matched for viral load, we found no difference in the proportion of senescent CD28(-CD57(+CD8(+ T cells between the groups. However, the frequency of Tim-3(+CD8(+ and Tim-3(+CD4(+ exhausted T cells, but not PD-1(+ T cells, was significantly increased in the adolescents with longer duration of infection compared to the children with shorter duration of HIV-1 infection. PD-1(+CD8(+ T cells were directly associated with T cell immune activation in children. The frequency of Tim-3(+CD8(+ T cells positively correlated with HIV-1 plasma viral load in the adolescents but not in the children. These data suggest that Tim-3 upregulation was driven by both HIV-1 viral replication and increased age, whereas PD-1 expression is associated with immune activation. These findings also suggest that the Tim-3 immune exhaustion phenotype rather than PD-1 or senescent cells plays an important role in age-related T cell dysfunction in perinatal HIV-1 infection. Targeting Tim-3 may serve as a novel therapeutic approach to improve immune control of virus replication and mitigate age related T cell exhaustion.

  11. Structure-based protein engineering efforts with a monomeric TIM variant: the importance of a single point mutation for generating an active site with suitable binding properties.

    Science.gov (United States)

    Alahuhta, Markus; Salin, Mikko; Casteleijn, Marco G; Kemmer, Christian; El-Sayed, Ibrahim; Augustyns, Koen; Neubauer, Peter; Wierenga, Rik K

    2008-04-01

    A monomeric variant of triosephosphate isomerase (TIM) with a new engineered binding groove has been characterized further. In this variant (ml8bTIM), the phosphate binding loop had been shortened, causing the binding site to be much more extended. Here, it is reported that in the V233A variant of ml8bTIM (A-TIM), three important properties of the wild-type TIM active site have been restored: (i) the structural properties of loop-7, (ii) the binding site of a conserved water molecule between loop-7 and loop-8 and (iii) the binding site of the phosphate moiety. It is shown that the active site of A-TIM can bind TIM transition state analogs and suicide inhibitors competently. It is found that the active site geometry of the A-TIM complexes is less compact and more solvent exposed, as in wild-type TIM. This correlates with the observation that the catalytic efficiency of A-TIM for interconverting the TIM substrates is too low to be detected. It is also shown that the A-TIM active site can bind compounds which do not bind to wild-type TIM and which are completely different from the normal TIM substrate, like a citrate molecule. The binding of this citrate molecule is stabilized by hydrogen bonding interactions with the new binding groove.

  12. Generating a knockdown transgene against Drosophila heterochromatic Tim17b gene encoding mitochondrial translocase subunit.

    Directory of Open Access Journals (Sweden)

    Mikael Garabedian

    Full Text Available Heterochromatic regions of eukaryotic genomes contain multiple functional elements involved in chromosomal dynamics, as well as multiple housekeeping genes. Cytological and molecular peculiarities of heterochromatic loci complicate genetic studies based on standard approaches developed using euchromatic genes. Here, we report the development of an RNAi-based knockdown transgenic construct and red fluorescent reporter transgene for a small gene, Tim17b, which localizes in constitutive heterochromatin of Drosophila melanogaster third chromosome and encodes a mitochondrial translocase subunit. We demonstrate that Tim17b protein is required strictly for protein delivery to mitochondrial matrix. Knockdown of Tim17b completely disrupts functions of the mitochondrial translocase complex. Using fluorescent recovery after photobleaching assay, we show that Tim17b protein has a very stable localization in the membranes of the mitochondrial network and that its exchange rate is close to zero when compared with soluble proteins of mitochondrial matrix. These results confirm that we have developed comprehensive tools to study functions of heterochromatic Tim17b gene.

  13. Tune Your Brown Clustering, Please

    DEFF Research Database (Denmark)

    Derczynski, Leon; Chester, Sean; Bøgh, Kenneth Sejdenfaden

    2015-01-01

    Brown clustering, an unsupervised hierarchical clustering technique based on ngram mutual information, has proven useful in many NLP applications. However, most uses of Brown clustering employ the same default configuration; the appropriateness of this configuration has gone predominantly...

  14. Natural Inhibitors of Maillard Browning

    Science.gov (United States)

    2013-12-01

    incorporated into pre-selected candidate ration components for evaluation via storage, sensory and chemical analysis. The concentration of inhibitor was...inhibiting Maillard browning, also known as non-enzymatic browning, a complex reaction which can lead to darkening of color, off- odors , off-flavors...nutritional intake, and decrease waste due to non-consumption of sensory degraded ration components. 1.1 Maillard Browning Maillard browning, also

  15. Mapping the Piute Mountains, CA with Thermal Infrared Multispectral Scanner (TIMS)

    Science.gov (United States)

    Hook, S. J.; Karlstrom, K. E.; Miller, C. F.; McCaffrey, K. J. W.

    1993-01-01

    Thermal Infrared Multispectral Scanner (TIMS) data were acquired in 1990 over the PiuteMountains, California to evaluate their usefulness for lithologic mapping in an area ofmetamorphosed, structurally complex, igneous and sedimentary rocks. The data were calibrated,atmospherically corrected, and emissivity variations extracted from them. There was an excellentvisual correlation between the units revealed in the TIMS data and the recent mapping in the easternside of the area. It was also possible to correct, improve and extend the recent map. For example,several areas of amphibolite were identified in the TIMS data that had been incorrectly mapped asgranodioritic gneiss, and the presence of a swarm of mafic dikes, of which only a few had previouslybeen identified, was revealed...

  16. TIM, a ray-tracing program for METATOY research and its dissemination

    Science.gov (United States)

    Lambert, Dean; Hamilton, Alasdair C.; Constable, George; Snehanshu, Harsh; Talati, Sharvil; Courtial, Johannes

    2012-03-01

    TIM (The Interactive METATOY) is a ray-tracing program specifically tailored towards our research in METATOYs, which are optical components that appear to be able to create wave-optically forbidden light-ray fields. For this reason, TIM possesses features not found in other ray-tracing programs. TIM can either be used interactively or by modifying the openly available source code; in both cases, it can easily be run as an applet embedded in a web page. Here we describe the basic structure of TIM's source code and how to extend it, and we give examples of how we have used TIM in our own research. Program summaryProgram title: TIM Catalogue identifier: AEKY_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEKY_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: GNU General Public License No. of lines in distributed program, including test data, etc.: 124 478 No. of bytes in distributed program, including test data, etc.: 4 120 052 Distribution format: tar.gz Programming language: Java Computer: Any computer capable of running the Java Virtual Machine (JVM) 1.6 Operating system: Any; developed under Mac OS X Version 10.6 RAM: Typically 145 MB (interactive version running under Mac OS X Version 10.6) Classification: 14, 18 External routines: JAMA [1] (source code included) Nature of problem: Visualisation of scenes that include scene objects that create wave-optically forbidden light-ray fields. Solution method: Ray tracing. Unusual features: Specifically designed to visualise wave-optically forbidden light-ray fields; can visualise ray trajectories; can visualise geometric optic transformations; can create anaglyphs (for viewing with coloured "3D glasses") and random-dot autostereograms of the scene; integrable into web pages. Running time: Problem-dependent; typically seconds for a simple scene.

  17. A quantitative analysis of TIMS data obtained on the Learjet 23 at various altitudes

    Science.gov (United States)

    Jaggi, S.

    1992-01-01

    A series of Thermal Infrared Multispectral Scanner (TIMS) data acquisition flights were conducted on the NASA Learjet 23 at different altitudes over a test site. The objective was to monitor the performance of the TIMS (its estimation of the brightness temperatures of the ground scene) with increasing altitude. The results do not show any significant correlation between the brightness temperatures and the altitude. The analysis indicates that the estimation of the temperatures is a function of the accuracy of the atmospheric correction used for each altitude.

  18. Prof. Dr. Rer. Nat. Burkhard Rauhut - Rector of RWTH Aachen University - Germany sign the golden book of the CERN. Greeting from Mr Sigurd Lettow, CERN Chief Financial Officer and Prof. Carlo Rubbia (ex CERN Director-General).

    CERN Multimedia

    Maximilien Brice

    2007-01-01

    Prof. Dr. Rer. Nat. Burkhard Rauhut - Rector of RWTH Aachen University - Germany sign the golden book of the CERN. Greeting from Mr Sigurd Lettow, CERN Chief Financial Officer and Prof. Carlo Rubbia (ex CERN Director-General).

  19. Fucoidans from brown seaweeds

    DEFF Research Database (Denmark)

    Ale, Marcel Tutor; Meyer, Anne S.

    2013-01-01

    structural details of fucoidans. Mild extraction techniques coupled with the use of new tools such as enzymes can provide the much needed knowledge about structural characteristics of different fucoidan molecules and thus pave the way for a better understanding of the structural chemistry and bioactivities......-proliferative effects on cancer cells. Recent work has revealed distinct structural features of fucoidans obtained from different brown seaweed sources. Fucoidans are classically obtained from brown seaweeds by multi-step, hot acid extraction, but the structural and compositional traits, and possibly the bioactivity......, of the fucoidan polysaccharides are significantly influenced by the extraction parameters. This review discusses the structural features of fucoidans, the significance of different extraction technologies, and reviews enzymatic degradation of fucoidans and the use of fucoidan-modifying enzymes for elucidating...

  20. Prof. M. G. K. Menon | History | About IASc | Indian Academy of ...

    Indian Academy of Sciences (India)

    Prof. M. G. K. Menon. President from 1974 to 1976. Prof. M. G. K. Menon. Name: MENON, Mambillikalathil Govind Kumar Elected 1964; Council Service: 1968-85; President: 1974-76; Vice-President: 1971-73. Member of Parliament, New Delhi Date of birth: 28 August 1928, Mangalore, Karnataka. Edn.: Jaswant College ...

  1. Involvement of Galectin-9/TIM-3 pathway in the systemic inflammatory response in early-onset preeclampsia.

    Science.gov (United States)

    Miko, Eva; Meggyes, Matyas; Bogar, Barbara; Schmitz, Nora; Barakonyi, Aliz; Varnagy, Akos; Farkas, Balint; Tamas, Peter; Bodis, Jozsef; Szekeres-Bartho, Julia; Illes, Zsolt; Szereday, Laszlo

    2013-01-01

    Preeclampsia is a common obstetrical disease affecting 3-5% of pregnancies and representing one of the leading causes of both maternal and fetal mortality. Maternal symptoms occur as an excessive systemic inflammatory reaction in response to the placental factors released by the oxidatively stressed and functional impaired placenta. The T-cell immunoglobulin domain and mucin domain (TIM) family is a relatively newly described group of molecules with a conserved structure and important immunological functions. Identification of Galectin-9 as a ligand for TIM-3 has established the Galectin-9/TIM-3 pathway as an important regulator of Th1 immunity and tolerance induction. The aim of our study was to investigate the expression and function of Galectin-9 and TIM-3 molecules by peripheral blood mononuclear cells and the possible role of Galectin-9/TIM-3 pathway in the immunoregulation of healthy pregnancy and early-onset preeclampsia. We determined TIM-3 and Gal-9 expression and cytotoxicicty of peripheral lymphocytes of early-onset preeclamptic women and healthy pregnant woman using flow cytometry. Investigating peripheral lymphocytes of women with early-onset preeclampsia, our results showed a decreased TIM-3 expression by T cells, cytotoxic T cells, NK cells and CD56(dim) NK cells compared to healthy pregnant women. Interestingly, we found a notably increased frequency of Galectin-9 positive cells in each investigated lymphocyte population in the case of early-onset preeclamptic patients. We further demonstrated increased cytotoxic activity by cytotoxic T and CD56(dim) NK cells in women with early-onset preeclampsia. Our findings showed that the strongest cellular cytotoxic response of lymphocytes occurred in the TIM-3 positive subpopulations of different lymphocytes subsets in early-onset preeclampsia. These data suggest that Gal-9/TIM-3 pathway could play an important role in the immune regulation during pregnancy and the altered Galectin-9 and TIM-3 expression

  2. Identity and Agonism: Tim Miller, Cornerstone, and the Politics of Community-Based Theatre.

    Science.gov (United States)

    Fletcher, John

    2003-01-01

    Contends that community-based theatre (CBT) can productively redefine the parameters of what "political performance" can mean. Draws on the work of community-based performance artist Tim Miller and on the author's experience as a dramaturg to suggest that artists and scholars must develop a revised idea of what constitutes activist democratic…

  3. Servicing the first web server - Tim Berners-Lee's NeXT

    CERN Multimedia

    unknown, Association aBCM

    2009-01-01

    In August 2009 a team from the Association aBCM in Lausanne came to CERN to give the world's first web server a health check under the watchful eye of web pioneer Robert Cailliau. They took an image of the hard drive at this time, copies of which were given to Robert Cailliau and Tim Berners-Lee.

  4. Consumerism, Activism, Intrinsic Motivation, and Balance: An Interview with Tim Kasser

    Science.gov (United States)

    Keeley, Jared

    2010-01-01

    A year after receiving his PhD in psychology from the University of Rochester, Tim Kasser accepted a position at Knox College, in Galesburg, Illinois, where he is currently professor of psychology. He regularly teaches psychology classes on personality, clinical and abnormal psychology, dreaming, and research methods, as well as an…

  5. Tim Allen, one of Hollywood's top comedy actors with Rolf Landua from CERN

    CERN Document Server

    Laurent Guiraud

    2000-01-01

    Tim Allen ('Galaxy Quest', 'For Richer and Poorer', 'The Santa Clause', Voice of 'Buzz Lightyear', in Toy Story 1 and 2), visited CERN in July 2000. He has a keen interest in modern physics. In his last book "I'm not really here" he contemplates the funny and the intriguing aspects of quantum physics in his daily life.

  6. Constructing a Writer's Voice: Ethos, Tim Cahill, and the Jonestown Massacre

    Science.gov (United States)

    Miller, Rich

    2007-01-01

    For over twenty years, Tim Cahill's writing has appeared in popular publications such as "Outside" and "Rolling Stone," and in many academic contexts, ranging from remedial and freshman composition textbooks to the use of his novels and short story collections in a variety of upper division literary courses. Cahill, then, is a…

  7. Ten Years Public Domain for the original Web Software : message from Tim Berners-Lee

    CERN Multimedia

    2003-01-01

    "CERN's decision to make the Web foundations and protocols available on a royalty free basis, and without additional impediments, was crucial to the Web's existence. Without this commitment, the enormous individual and corporate investment in Web technology simply would never have happened, and we wouldn't have the Web today." (Tim Berners-Lee, Director, WWW Consortium)

  8. The Filmmaker as Humanist: An Interview with Tim Robbins on the Making of "Cradle Will Rock".

    Science.gov (United States)

    Mason, Terrence C.

    2000-01-01

    Presents an interview with Tim Robbins that focuses on the making of the film "Cradle Will Rock." Robbins offers his perspectives on issues such as the power of art to convey important social messages and sources of violence in schools. Includes resources for teachers. (CMK)

  9. Towards Discovery and Targeted Peptide Biomarker Detection Using nanoESI-TIMS-TOF MS

    Science.gov (United States)

    Garabedian, Alyssa; Benigni, Paolo; Ramirez, Cesar E.; Baker, Erin S.; Liu, Tao; Smith, Richard D.; Fernandez-Lima, Francisco

    2017-09-01

    In the present work, the potential of trapped ion mobility spectrometry coupled to TOF mass spectrometry (TIMS-TOF MS) for discovery and targeted monitoring of peptide biomarkers from human-in-mouse xenograft tumor tissue was evaluated. In particular, a TIMS-MS workflow was developed for the detection and quantification of peptide biomarkers using internal heavy analogs, taking advantage of the high mobility resolution (R = 150-250) prior to mass analysis. Five peptide biomarkers were separated, identified, and quantified using offline nanoESI-TIMS-CID-TOF MS; the results were in good agreement with measurements using a traditional LC-ESI-MS/MS proteomics workflow. The TIMS-TOF MS analysis permitted peptide biomarker detection based on accurate mobility, mass measurements, and high sequence coverage for concentrations in the 10-200 nM range, while simultaneously achieving discovery measurements of not initially targeted peptides as markers from the same proteins and, eventually, other proteins. [Figure not available: see fulltext.

  10. El De imaginibus caelestibus de Ibn al-Ḥātim

    Directory of Open Access Journals (Sweden)

    Oliveras, Marc

    2009-06-01

    Full Text Available K. Lippincott and D. Pingree published in 1987 a first Latin edition and English translation of the 15th bilingual Arabic-Latin De imaginibus caelestibus, written originally by the Andalusian Ibn al-Ḥātim in the 10th century. The paper presented here aims to complete the preceding one with an Arabic edition, Spanish translation and some interpretations on the possible sources of talismanic imagery. In this brief astromagic treatise, Ibn al-Ḥātim focuses on twenty eight talismans, related to the lunar mansions, and their magical properties.

    En 1987 K. Lippincott y D. Pingree publicaron una primera edición latina junto a una traducción inglesa del tratado bilingüe árabo-latino del s. XV De imaginibus caelestibus, escrito originariamente por el andalusí Ibn al-Ḥātim en el s. X. El trabajo que se presenta aquí pretende completar al precedente con una edición del texto árabe, su traducción al español y añadir algunas interpretaciones a las posibles fuentes de la imaginería talismánica. En este breve tratado de astromagia, Ibn al-Ḥātim se dedica principalmente a describir veintiocho talismanes, relacionados con las mansiones lunares, y sus propiedades mágicas.

  11. Public Lecture | The long road to the LHC | Prof. Lyn Evans, Dr. Daniel Treille and Prof. Peter Jenni | 9 October

    CERN Multimedia

    2014-01-01

    “The long road to the LHC” by Prof. Lyn Evans, Dr. Daniel Treille and Prof. Peter Jenni. Thursday 9 October, 7.30 p.m. in the Globe of Science and Innovation. Talk in English with simultaneous interpreting into French.  Entrance free. Limited number of seats. Reservation essential: +41 22 767 76 76 or cern.reception@cern.ch   Lyn Evans. Lecture by Lyn Evans Abstract The key to the discovery of the Higgs boson has been the development of particle accelerators at CERN over the years. I will explain how a particle accelerator works and will follow the path from the construction of the Proton Synchrotron in the 1950s to the world’s most powerful colliding beam machine, the Large Hadron Collider. Biography Born in 1945, Lyn Evans has spent his whole career in the field of high energy physics and particle accelerators, participating in all the great projects of CERN. From 1993 he led the team that designed, built and commissioned the LHC. He is currently ...

  12. Combination Therapy with Anti-PD-1, Anti-TIM-3, and Focal Radiation Results in Regression of Murine Gliomas.

    Science.gov (United States)

    Kim, Jennifer E; Patel, Mira A; Mangraviti, Antonella; Kim, Eileen S; Theodros, Debebe; Velarde, Esteban; Liu, Ann; Sankey, Eric W; Tam, Ada; Xu, Haiying; Mathios, Dimitrios; Jackson, Christopher M; Harris-Bookman, Sarah; Garzon-Muvdi, Tomas; Sheu, Mary; Martin, Allison M; Tyler, Betty M; Tran, Phuoc T; Ye, Xiaobu; Olivi, Alessandro; Taube, Janis M; Burger, Peter C; Drake, Charles G; Brem, Henry; Pardoll, Drew M; Lim, Michael

    2017-01-01

    Checkpoint molecules like programmed death-1 (PD-1) and T-cell immunoglobulin mucin-3 (TIM-3) are negative immune regulators that may be upregulated in the setting of glioblastoma multiforme. Combined PD-1 blockade and stereotactic radiosurgery (SRS) have been shown to improve antitumor immunity and produce long-term survivors in a murine glioma model. However, tumor-infiltrating lymphocytes (TIL) can express multiple checkpoints, and expression of ≥2 checkpoints corresponds to a more exhausted T-cell phenotype. We investigate TIM-3 expression in a glioma model and the antitumor efficacy of TIM-3 blockade alone and in combination with anti-PD-1 and SRS. C57BL/6 mice were implanted with murine glioma cell line GL261-luc2 and randomized into 8 treatment arms: (i) control, (ii) SRS, (iii) anti-PD-1 antibody, (iv) anti-TIM-3 antibody, (v) anti-PD-1 + SRS, (vi) anti-TIM-3 + SRS, (vii) anti-PD-1 + anti-TIM-3, and (viii) anti-PD-1 + anti-TIM-3 + SRS. Survival and immune activation were assessed. Dual therapy with anti-TIM-3 antibody + SRS or anti-TIM-3 + anti-PD-1 improved survival compared with anti-TIM-3 antibody alone. Triple therapy resulted in 100% overall survival (P < 0.05), a significant improvement compared with other arms. Long-term survivors demonstrated increased immune cell infiltration and activity and immune memory. Finally, positive staining for TIM-3 was detected in 7 of 8 human GBM samples. This is the first preclinical investigation on the effects of dual PD-1 and TIM-3 blockade with radiation. We also demonstrate the presence of TIM-3 in human glioblastoma multiforme and provide preclinical evidence for a novel treatment combination that can potentially result in long-term glioma survival and constitutes a novel immunotherapeutic strategy for the treatment of glioblastoma multiforme. Clin Cancer Res; 23(1); 124-36. ©2016 AACR. ©2016 American Association for Cancer Research.

  13. Speakers at CERN's LEP celebration on 9 October 2000 - L. to r. : M. Philippe Busquin, Commissioner for Research European Union; Prof. Marino Gago, Minister of Science and Technology Portugal; Prof. Dimitar Dimitrov, Minister of Education and Science Bulgaria; M. Lubomir Fogas, Deputy Prime Minister Slovak Republic and Prof. Andrzej Wiszniewski Minister of Science Poland : during the LEP celebration.

    CERN Document Server

    Laurent Guiraud

    2000-01-01

    Speakers at CERN's LEP celebration on 9 October 2000 - L. to r. : M. Philippe Busquin, Commissioner for Research European Union; Prof. Marino Gago, Minister of Science and Technology Portugal; Prof. Dimitar Dimitrov, Minister of Education and Science Bulgaria; M. Lubomir Fogas, Deputy Prime Minister Slovak Republic and Prof. Andrzej Wiszniewski Minister of Science Poland : during the LEP celebration.

  14. Prof dr FJ van Zyl as mens, kerkman en godsdiensfilosoof

    Directory of Open Access Journals (Sweden)

    P. J. van der Merwe

    1989-01-01

    Full Text Available Prof Dr FJ van Zyl as person, church personality and philosopher of religion Professor Francois Jacobus van Zyl (1913-05-06 - served as Head of the Department of Science of Religion and Missiology, Faculty of Theology (Section: Nederduitsch Hervormde Kerk, University of Pretoria, during the period 1960-1978. This article (written by a former student of his and present Head of the same Department contains a short biography, a discussion of his views on Theology, Science of Religion and Philosophy of Religion, and a bibliography. He is portrayed as a theologian with Barthian convictions, while been influenced by Emil Brunner and to a lesser extent by Hendrik Kraemer also. His primary audience was the Nederduitsch Hervormde Kerk and his theological activities (especially in the period 1960-1983 must be seen in relation to his influential role in same church.

  15. [Brown recluse bite].

    Science.gov (United States)

    Nehemya, Moshe

    2008-01-01

    Spider bites are not uncommon in our warm climate. The most prevalent species of venomous spiders in Israel are the brown recluse and the black widow. Although the black widow is more notorious than the recluse, for every bite by a black widow there are hundreds of recluse bites reported. Despite the numerous bites, there is little awareness amongst physicians with regard to the clinical signs of recluse bites, and very often the wrong diagnosis is made, resulting in complex and unnecessary treatments. The basis of this error stems from the numerous clinical diagnoses which closely imitate a recluse bite, the relative scarceness of documented recluse bites and the fact that in most cases the spider is not witnessed by the victim. The following article describes three cases of children admitted to our department, presenting with high fever, a necrotic lesion and an extensive maculopapular rash. The children were eventually diagnosed with brown recluse bites. Furthermore, the article summarizes the literature regarding the clinical signs of recluse bites, possible complications and treatment options. The objective of this review is to increase awareness towards recluse bites, thereby preventing misdiagnoses and unnecessary treatments.

  16. Correlation of fitness landscapes from three orthologous TIM barrels originates from sequence and structure constraints

    Science.gov (United States)

    Chan, Yvonne H.; Venev, Sergey V.; Zeldovich, Konstantin B.; Matthews, C. Robert

    2017-01-01

    Sequence divergence of orthologous proteins enables adaptation to environmental stresses and promotes evolution of novel functions. Limits on evolution imposed by constraints on sequence and structure were explored using a model TIM barrel protein, indole-3-glycerol phosphate synthase (IGPS). Fitness effects of point mutations in three phylogenetically divergent IGPS proteins during adaptation to temperature stress were probed by auxotrophic complementation of yeast with prokaryotic, thermophilic IGPS. Analysis of beneficial mutations pointed to an unexpected, long-range allosteric pathway towards the active site of the protein. Significant correlations between the fitness landscapes of distant orthologues implicate both sequence and structure as primary forces in defining the TIM barrel fitness landscape and suggest that fitness landscapes can be translocated in sequence space. Exploration of fitness landscapes in the context of a protein fold provides a strategy for elucidating the sequence-structure-fitness relationships in other common motifs. PMID:28262665

  17. Tim, Jan Lucas ja Karl Robert - vennad üheks kuuks / Maris Laurits

    Index Scriptorium Estoniae

    Laurits, Maris

    2009-01-01

    Rakvere Teatri suvelavastuse "Vennad Lõvisüdamed" kaks Karli osatäitjat Jan Lucas Videvik ja Tim Leesnurm ning Joonatani osatäitja Karl Robert Saaremäe tegid Loksal Kaldmaa talus ratsasõiduproove. Üllar Saaremäe lavastuse "Vennad Lõvisüdamed" (Astrid Lindgreni samanimelise jutustuse järgi) esietendus on 11. juunil Rakvere teatri taga aias

  18. A COMPARISON OF SOME TRANSLATIONS OF GOOGLE AND THOSE OF TIM KUNCI CULTURAL STUDIES CENTER

    Directory of Open Access Journals (Sweden)

    Asril Marjohan Marjohan

    2015-02-01

    Full Text Available This study was aimed at describing Google translations by comparing them with those which were carried out by humans. The human translations used in this study were done by Tim Kunci Cultural Studies Center. This study used qualitative-descriptive method. The sample was purposively selected and consisted of 24 sentences from Chris Barker, Cultural Studies and their two translated versions. The evaluation was done by using Sical’s approach. The results showed that Google translations contained more errors than those made by Tim Kunci Cultural Studies Center. Google made errors that fell into the category of violations of linguistic and sociocultural rules or norms. This was caused by the design of Google Translate that was not based on linguistic and sociocultural analyses.  Meanwhile   Tim Kunci Cultural Studies Center made errors that indicated reasoning by guessing meanings from context, as what humans are doing in communication. Google translations needed revising in  the forms of translating words which had been left untranslated, retranslating words which had been wrongly translated because of not considering context, retranslating phrases which had been wrongly translated because of  not analyzing them into their constituents and propositions, retranslating words which had been wrongly translated because of not considering sociocultural norms. In doing the revisions the editor had to read the original text because the translations tended not to give clues to the original patterns of the sentences for their highly varied forms.   Meanwhile, the translations of Tim Kunci Cultural Studies Center needed minor editing to make them more effective. There was no need for an intensive reading of the original for their   more systematic characteristics.

  19. TIM INFLI,'ENCE OF VASECTOMIZED RAMS ON THE III"T{BING ...

    African Journals Online (AJOL)

    TIM INFLI,'ENCE OF VASECTOMIZED RAMS ON THE III"T{BING PATTERN OF. OF SPRINGMATED CORRIEDALE EWES. B.P. Louw, F.E. Il{arx & G.D. Yates. Reeipt of MS 23.1.74. hllqe of Agriatlture and Reswch Institute, hiwte W X9059, Pietqmuitzburg. According to Hrm&r (1959, 1962,1964) thc spxual activity of thc erye ...

  20. Influence of galectin-9/Tim-3 interaction on herpes simplex virus-1 latency.

    Science.gov (United States)

    Reddy, Pradeep B J; Sehrawat, Sharvan; Suryawanshi, Amol; Rajasagi, Naveen K; Mulik, Sachin; Hirashima, Mitsuomi; Rouse, Barry T

    2011-12-01

    After HSV-1 infection, CD8(+) T cells accumulate in the trigeminal ganglion (TG) and participate in the maintenance of latency. However, the mechanisms underlying intermittent virus reactivation are poorly understood. In this study, we demonstrate the role of an inhibitory interaction between T cell Ig and mucin domain-containing molecule 3 (Tim-3)-expressing CD8(+) T cells and galectin 9 (Gal-9) that could influence HSV-1 latency and reactivation. Accordingly, we show that most K(b)-gB tetramer-specific CD8(+) T cells in the TG of HSV-1-infected mice express Tim-3, a molecule that delivers negative signals to CD8(+) T cells upon engagement of its ligand Gal-9. Gal-9 was also upregulated in the TG when replicating virus was present as well during latency. This could set the stage for Gal-9/Tim-3 interaction, and this inhibitory interaction was responsible for reduced CD8(+) T cell effector function in wild-type mice. Additionally, TG cell cultures exposed to recombinant Gal-9 in the latent phase caused apoptosis of most CD8(+) T cells. Furthermore, Gal-9 knockout TG cultures showed delayed and reduced viral reactivation as compared with wild-type cultures, demonstrating the greater efficiency of CD8(+) T cells to inhibit virus reactivation in the absence of Gal-9. Moreover, the addition of recombinant Gal-9 to ex vivo TG cultures induced enhanced viral reactivation compared with untreated controls. Our results demonstrate that the host homeostatic mechanism mediated by Gal-9/Tim-3 interaction on CD8(+) T cells can influence the outcome of HSV-1 latent infection, and manipulating Gal-9 signals might represent therapeutic means to inhibit HSV-1 reactivation from latency.

  1. Järgmise lainega võivad tulla meile Ühendriikide investorid / Tim Ferland ; interv. Margit Aedla

    Index Scriptorium Estoniae

    Ferland, Tim

    2003-01-01

    Eestis asuva Ameerika Kaubanduskoja (ACCE) president Tim Ferland analüüsib Eesti senist arengut, EL-iga liitumise mõju tulevasele majanduslikule arengule, Eesti ning USA majandus- ja kaubandussuhete olukorda

  2. Betaalpha-hairpin clamps brace betaalphabeta modules and can make substantive contributions to the stability of TIM barrel proteins.

    Directory of Open Access Journals (Sweden)

    Xiaoyan Yang

    Full Text Available Non-local hydrogen bonding interactions between main chain amide hydrogen atoms and polar side chain acceptors that bracket consecutive betaalpha or alphabeta elements of secondary structure in alphaTS from E. coli, a TIM barrel protein, have previously been found to contribute 4-6 kcal mol(-1 to the stability of the native conformation. Experimental analysis of similar betaalpha-hairpin clamps in a homologous pair of TIM barrel proteins of low sequence identity, IGPS from S. solfataricus and E. coli, reveals that this dramatic enhancement of stability is not unique to alphaTS. A survey of 71 TIM barrel proteins demonstrates a 4-fold symmetry for the placement of betaalpha-hairpin clamps, bracing the fundamental betaalphabeta building block and defining its register in the (betaalpha(8 motif. The preferred sequences and locations of betaalpha-hairpin clamps will enhance structure prediction algorithms and provide a strategy for engineering stability in TIM barrel proteins.

  3. Using the thermal infrared multispectral scanner (TIMS) to estimate surface thermal responses

    Science.gov (United States)

    Luvall, J. C.; Holbo, H. R.

    1987-01-01

    A series of measurements was conducted over the H.J. Andrews, Oregon, experimental coniferous forest, using airborne thermal infrared multispectral scanner (TIMS). Flight lines overlapped, with a 28-min time difference between flight lines. Concurrent radiosonde measurements of atmospheric profiles of air temperature and moisture were used for atmospheric radiance corrections of the TIMS data. Surface temperature differences over time between flight lines were used to develop thermal response numbers (TRNs) which characterized the thermal response (in KJ/sq m/C, where K is the measured incoming solar radiation) of the different surface types. The surface types included a mature forest (canopy dominated by dense crowns of Pseudosuga menziesii, with a secondary canopy of dense Tsuga heterophylla, and also a tall shrub layer of Acer circinatum) and a two-year-old clear-cut. The temperature distribution, within TIMS thermal images was found to reflect the surface type examined. The clear-cut surface had the lowest TRN, while mature Douglas fir the highest.

  4. Role of TIM-4 in exosome-dependent entry of HIV-1 into human immune cells.

    Science.gov (United States)

    Sims, Brian; Farrow, Anitra L; Williams, Sparkle D; Bansal, Anju; Krendelchtchikov, Alexandre; Gu, Linlin; Matthews, Qiana L

    2017-01-01

    Exosomes, 30-200 nm nanostructures secreted from donor cells and internalized by recipient cells, can play an important role in the cellular entry of some viruses. These microvesicles are actively secreted into various body fluids, including blood, urine, saliva, cerebrospinal fluid, and breast milk. We successfully isolated exosomes from human breast milk and plasma. The size and concentration of purified exosomes were measured by nanoparticle tracking, while Western blotting confirmed the presence of the exosomal-associated proteins CD9 and CD63, clathrin, and T cell immunoglobulin and mucin proteins (TIMs). Through viral infection assays, we determined that HIV-1 utilizes an exosome-dependent mechanism for entry into human immune cells. The virus contains high amounts of phosphatidylserine (PtdSer) and may bind PtdSer receptors, such as TIMs. This mechanism is supported by our findings that exosomes from multiple sources increased HIV-1 entry into T cells and macrophages, and viral entry was potently blocked with anti-TIM-4 antibodies.

  5. Voordrag vir die toekenning van die graad Doctor Educationis, honoris causa, aan prof. dr. Jan Waterink.

    Directory of Open Access Journals (Sweden)

    J. C. Coetzee

    1955-03-01

    Full Text Available Die Raad en die Senaat het op hul vergaderinge in November 1954 besluit om aan prof. dr. Jan Waterink, gebore 20 Oktober 1890, die graad Doctor Educationis honoris causa toe te ken.

  6. NSA Prof. Ostovar Publishes on Iran's Foreign Policy in the Middle East

    OpenAIRE

    Grant, Catherine

    2016-01-01

    National Security Affairs (NSA) News NSA Prof. Afshon Ostovar has written an article titled “From Tehran to Mosul: Iran and the Middle East's Great Game” for the November issue of Foreign Affairs.

  7. Cis association of galectin-9 with Tim-3 differentially regulates IL-12/IL-23 expressions in monocytes via TLR signaling.

    Directory of Open Access Journals (Sweden)

    Cheng J Ma

    Full Text Available Human monocytes/macrophages (M/M(Ф of the innate immunity sense and respond to microbial products via specific receptor coupling with stimulatory (such as TLR and inhibitory (such as Tim-3 receptors. Current models imply that Tim-3 expression on M/M(Ø can deliver negative signaling to TLR-mediated IL-12 expression through trans association with its ligand Galectin-9 (Gal-9 presented by other cells. However, Gal-9 is also expressed within M/M(Ø, and the effect of intracellular Gal-9 on Tim-3 activities and inflammatory responses in the same M/M(Ø remains unknown. In this study, our data suggest that Tim-3 and IL-12/IL-23 gene transcriptions are regulated by enhanced or silenced Gal-9 expression within monocytes through synergizing with TLR signaling. Additionally, TLR activation facilitates Gal-9/Tim-3 cis association within the same M/M(Ø to differentially regulate IL-12/IL-23 expressions through STAT-3 phosphorylation. These results reveal a ligand (Gal-9 compartment-dependent regulatory effect on receptor (Tim-3 activities and inflammatory responses via TLR pathways--a novel mechanism underlying cellular responses to external or internal cues.

  8. Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice

    Science.gov (United States)

    Xiao, Sheng; Brooks, Craig R.; Zhu, Chen; Wu, Chuan; Sweere, Johanna M.; Petecka, Sonia; Yeste, Ada; Quintana, Francisco J.; Ichimura, Takaharu; Sobel, Raymond A.; Bonventre, Joseph V.; Kuchroo, Vijay K.

    2012-01-01

    Tim-1, a type I transmembrane glycoprotein, consists of an IgV domain and a mucin domain. The IgV domain is essential for binding Tim-1 to its ligands, but little is known about the role of the mucin domain, even though genetic association of TIM-1 with atopy/asthma has been linked to the length of mucin domain. We generated a Tim-1–mutant mouse (Tim-1Δmucin) in which the mucin domain was deleted genetically. The mutant mice showed a profound defect in IL-10 production from regulatory B cells (Bregs). Associated with the loss of IL-10 production in B cells, older Tim-1Δmucin mice developed spontaneous autoimmunity associated with hyperactive T cells, with increased production of IFN-γ and elevated serum levels of Ig and autoantibodies. However, Tim-1Δmucin mice did not develop frank systemic autoimmune disease unless they were crossed onto the Fas-mutant lpr mice on a C57BL/6 background. Tim-1Δmucinlpr mice developed accelerated and fulminant systemic autoimmunity with accumulation of abnormal double-negative T cells and autoantibodies to a number of lupus-associated autoantigens. Thus, Tim-1 plays a critical role in maintaining suppressive Breg function, and our data also demonstrate an unexpected role of the Tim-1 mucin domain in regulating Breg function and maintaining self-tolerance. PMID:22773818

  9. Involvement of Galectin-9/TIM-3 pathway in the systemic inflammatory response in early-onset preeclampsia.

    Directory of Open Access Journals (Sweden)

    Eva Miko

    Full Text Available Preeclampsia is a common obstetrical disease affecting 3-5% of pregnancies and representing one of the leading causes of both maternal and fetal mortality. Maternal symptoms occur as an excessive systemic inflammatory reaction in response to the placental factors released by the oxidatively stressed and functional impaired placenta. The T-cell immunoglobulin domain and mucin domain (TIM family is a relatively newly described group of molecules with a conserved structure and important immunological functions. Identification of Galectin-9 as a ligand for TIM-3 has established the Galectin-9/TIM-3 pathway as an important regulator of Th1 immunity and tolerance induction.The aim of our study was to investigate the expression and function of Galectin-9 and TIM-3 molecules by peripheral blood mononuclear cells and the possible role of Galectin-9/TIM-3 pathway in the immunoregulation of healthy pregnancy and early-onset preeclampsia. We determined TIM-3 and Gal-9 expression and cytotoxicicty of peripheral lymphocytes of early-onset preeclamptic women and healthy pregnant woman using flow cytometry.Investigating peripheral lymphocytes of women with early-onset preeclampsia, our results showed a decreased TIM-3 expression by T cells, cytotoxic T cells, NK cells and CD56(dim NK cells compared to healthy pregnant women. Interestingly, we found a notably increased frequency of Galectin-9 positive cells in each investigated lymphocyte population in the case of early-onset preeclamptic patients. We further demonstrated increased cytotoxic activity by cytotoxic T and CD56(dim NK cells in women with early-onset preeclampsia. Our findings showed that the strongest cellular cytotoxic response of lymphocytes occurred in the TIM-3 positive subpopulations of different lymphocytes subsets in early-onset preeclampsia.These data suggest that Gal-9/TIM-3 pathway could play an important role in the immune regulation during pregnancy and the altered Galectin-9 and TIM-3

  10. TIM1 (HAVCR1) Is Not Essential for Cellular Entry of Either Quasi-enveloped or Naked Hepatitis A Virions

    Science.gov (United States)

    Das, Anshuman; Hirai-Yuki, Asuka; González-López, Olga; Rhein, Bethany; Moller-Tank, Sven; Brouillette, Rachel; Hensley, Lucinda; Misumi, Ichiro; Lovell, William; Cullen, John M.; Whitmire, Jason K.; Maury, Wendy

    2017-01-01

    ABSTRACT Receptor molecules play key roles in the cellular entry of picornaviruses, and TIM1 (HAVCR1) is widely accepted to be the receptor for hepatitis A virus (HAV), an unusual, hepatotropic human picornavirus. However, its identification as the hepatovirus receptor predated the discovery that hepatoviruses undergo nonlytic release from infected cells as membrane-cloaked, quasi-enveloped HAV (eHAV) virions that enter cells via a pathway distinct from naked, nonenveloped virions. We thus revisited the role of TIM1 in hepatovirus entry, examining both adherence and infection/replication in cells with clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9-engineered TIM1 knockout. Cell culture-derived, gradient-purified eHAV bound Huh-7.5 human hepatoma cells less efficiently than naked HAV at 4°C, but eliminating TIM1 expression caused no difference in adherence of either form of HAV, nor any impact on infection and replication in these cells. In contrast, TIM1-deficient Vero cells showed a modest reduction in quasi-enveloped eHAV (but not naked HAV) attachment and replication. Thus, TIM1 facilitates quasi-enveloped eHAV entry in Vero cells, most likely by binding phosphatidylserine (PtdSer) residues on the eHAV membrane. Both Tim1−/− Ifnar1−/− and Tim4−/− Ifnar1−/− double-knockout mice were susceptible to infection upon intravenous challenge with infected liver homogenate, with fecal HAV shedding and serum alanine aminotransferase (ALT) elevations similar to those in Ifnar1−/− mice. However, intrahepatic HAV RNA and ALT elevations were modestly reduced in Tim1−/−Ifnar1−/− mice compared to Ifnar1−/− mice challenged with a lower titer of gradient-purified HAV or eHAV. We conclude that TIM1 is not an essential hepatovirus entry factor, although its PtdSer-binding activity may contribute to the spread of quasi-enveloped virus and liver injury in mice. PMID:28874468

  11. TIM1 (HAVCR1 Is Not Essential for Cellular Entry of Either Quasi-enveloped or Naked Hepatitis A Virions

    Directory of Open Access Journals (Sweden)

    Anshuman Das

    2017-09-01

    Full Text Available Receptor molecules play key roles in the cellular entry of picornaviruses, and TIM1 (HAVCR1 is widely accepted to be the receptor for hepatitis A virus (HAV, an unusual, hepatotropic human picornavirus. However, its identification as the hepatovirus receptor predated the discovery that hepatoviruses undergo nonlytic release from infected cells as membrane-cloaked, quasi-enveloped HAV (eHAV virions that enter cells via a pathway distinct from naked, nonenveloped virions. We thus revisited the role of TIM1 in hepatovirus entry, examining both adherence and infection/replication in cells with clustered regularly interspaced short palindromic repeat (CRISPR/Cas9-engineered TIM1 knockout. Cell culture-derived, gradient-purified eHAV bound Huh-7.5 human hepatoma cells less efficiently than naked HAV at 4°C, but eliminating TIM1 expression caused no difference in adherence of either form of HAV, nor any impact on infection and replication in these cells. In contrast, TIM1-deficient Vero cells showed a modest reduction in quasi-enveloped eHAV (but not naked HAV attachment and replication. Thus, TIM1 facilitates quasi-enveloped eHAV entry in Vero cells, most likely by binding phosphatidylserine (PtdSer residues on the eHAV membrane. Both Tim1−/− Ifnar1−/− and Tim4−/− Ifnar1−/− double-knockout mice were susceptible to infection upon intravenous challenge with infected liver homogenate, with fecal HAV shedding and serum alanine aminotransferase (ALT elevations similar to those in Ifnar1−/− mice. However, intrahepatic HAV RNA and ALT elevations were modestly reduced in Tim1−/−Ifnar1−/− mice compared to Ifnar1−/− mice challenged with a lower titer of gradient-purified HAV or eHAV. We conclude that TIM1 is not an essential hepatovirus entry factor, although its PtdSer-binding activity may contribute to the spread of quasi-enveloped virus and liver injury in mice.

  12. Upregulation of the Tim-3/galectin-9 pathway of T cell exhaustion in chronic hepatitis B virus infection.

    Directory of Open Access Journals (Sweden)

    Gaia Nebbia

    Full Text Available The S-type lectin galectin-9 binds to the negative regulatory molecule Tim-3 on T cells and induces their apoptotic deletion or functional inactivation. We investigated whether galectin-9/Tim-3 interactions contribute to the deletion and exhaustion of the antiviral T cell response in chronic hepatitis B virus infection (CHB. We found Tim-3 to be expressed on a higher percentage of CD4 and CD8 T cells from patients with CHB than healthy controls (p<0.0001 and to be enriched on activated T cells and those infiltrating the HBV-infected liver. Direct ex vivo examination of virus-specific CD8 T cells binding HLA-A2/peptide multimers revealed that Tim-3 was more highly upregulated on HBV-specific CD8 T cells than CMV-specific CD8 T cells or the global CD8 T cell population in patients with CHB (p<0.001 or than on HBV-specific CD8 after resolution of infection. T cells expressing Tim-3 had an impaired ability to produce IFN-γ and TNF-α upon recognition of HBV-peptides and were susceptible to galectin-9-triggered cell death in vitro. Galectin-9 was detectable at increased concentrations in the sera of patients with active CHB-related liver inflammation (p = 0.02 and was strongly expressed by Kupffer cells within the liver sinusoidal network. Tim-3 blockade resulted in enhanced expansion of HBV-specific CD8 T cells able to produce cytokines and mediate cytotoxicity in vitro. Blocking PD-1 in combination with Tim-3 enhanced the number of patients from whom functional antiviral responses could be recovered and/or the strength of responses, indicating that these co-inhibitory molecules play a non-redundant role in driving T cell exhaustion in CHB. Patients taking antivirals able to potently suppress HBV viraemia continued to express Tim-3 on their T cells and respond to Tim-3 blockade. In summary, both Tim-3 and galectin-9 are increased in CHB and may contribute to the inhibition and deletion of T cells as they infiltrate the HBV-infected liver.

  13. Tim de Zeeuw to Become the Next Director General of ESO

    Science.gov (United States)

    2007-01-01

    The ESO Council has just appointed Tim de Zeeuw, 50, as the next Director General of ESO, effective as of 1 September 2007, when the current Director General, Catherine Cesarsky will complete her mandate. ESO PR Photo 02/07 ESO PR Photo 03/07 Professor Tim de Zeeuw "ESO is Europe's flagship organisation for ground-based astronomy," said, Richard Wade, President of the ESO Council. "The ESO Council is very pleased that Professor de Zeeuw has accepted the task as its next Director General. He has played a key role over the last few years in developing a strategic vision for ESO, and I have every confidence that he will now lead the organisation in the realisation of that exciting vision." Tim de Zeeuw has an excellent record, both as a highly respected scientist and as a leader of an internationally recognised science institute in the Netherlands. He is Scientific Director of the Leiden Observatory, a research institute in the College of Mathematics and Natural Sciences of Leiden University. Tim de Zeeuw also has considerable experience as regards science policy issues. Catherine Cesarsky, ESO's current Director General commented: "Over the recent years, ESO has developed considerably with more activities and new member states, and with its ambitious project portfolio, ESO is clearly facing an exciting future. I shall be delighted to pass the baton to Tim de Zeeuw, who as a recent Council member is very familiar with our Organisation." "It is a great honour and an exciting challenge to lead this world-class organisation in the years to come in support of one of the most dynamic areas of science today," said de Zeeuw. "I look forward to overseeing the continued upgrading of the Very Large Telescope with the second-generation instrumentation and the completion of the ALMA project, and in particular to help developing the future European Extremely Large Telescope." Tim de Zeeuw's main research interests embrace the formation, structure and dynamics of galaxies

  14. Negative CD4 + TIM-3 signaling confers resistance against cold preservation damage in mouse liver transplantation.

    Science.gov (United States)

    Liu, Yuanxing; Ji, Haofeng; Zhang, Yu; Shen, Xiu-da; Gao, Feng; Nguyen, Terry T; Shang, Xuanming; Lee, Nayun; Busuttil, Ronald W; Kupiec-Weglinski, Jerzy W

    2015-04-01

    Ischemia-reperfusion injury (IRI), an innate immunity-driven local inflammation, remains the major problem in clinical organ transplantation. T cell immunoglobulin and mucin domain (TIM-3)-Galectin-9 (Gal-9) signaling regulates CD4+ Th1 immune responses. Here, we explored TIM-3-Gal-9 function in a clinically relevant murine model of hepatic cold storage and orthotopic liver transplantation (OLT). C57BL/6 livers, preserved for 20 h at 4°C in UW solution, were transplanted to syngeneic mouse recipients. Up-regulation of TIM-3 on OLT-infiltrating activated CD4+ T cells was observed in the early IRI phase (1 h). By 6 h of reperfusion, OLTs in recipients treated with a blocking anti-TIM-3 Ab were characterized by: (1) enhanced hepatocellular damage (sALT levels, liver Suzuki's histological score); (2) polarized cell infiltrate towards Th1/Th17-type phenotype; (3) depressed T cell exhaustion markers (PD-1, LAG3); and (4) elevated neutrophil and macrophage infiltration/activation. In parallel studies, adoptive transfer of CD4+ T cells from naïve WT, but not from TIM-3 Tg donors, readily recreated OLT damage in otherwise IR-resistant RAG(-/-) test recipients. Furthermore, pre-treatment of mice with rGal-9 promoted hepatoprotection against preservation-association liver damage, accompanied by enhanced TIM-3 expression in OLTs. Thus, CD4+ T cell-dependent "negative" TIM-3 costimulation is essential for hepatic homeostasis and resistance against IR stress in OLTs. © Copyright 2015 The American Society of Transplantation and the American Society of Transplant Surgeons.

  15. Interference with Tim-3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

    Science.gov (United States)

    Yu, Muming; Lu, Bin; Liu, Yancun; Me, Ying; Wang, Lijun; Li, Hui

    2017-01-01

    Tumor cells resistant to anoikis are considered to be candidates for metastasis. In the present study, the role of Tim-3 in anoikis and its influence on the invasion of clear cell renal cell carcinoma (ccRCC) was investigated. Here, polyhydroxylethylmethacrylate (poly-HEMA) was applied to two ccRCC cell lines, 786-O and Caki-2, to induce detachment from the extracellular matrix (ECM). Tim-3 mRNA and protein expression levels were assayed by reverse transcription-quantitative polymerase chain reaction (RT-qPCR) and western blot, respectively. Anoikis was measured by Ho33342/PI double staining, acridine orange staining, and further determined using the CytoSelect™ 24-well Anoikis Assay kit. Apoptosis was measured using flow cytometry, E-cadherin and N-cadherin protein expression were determined using western blotting and a Chemicon cell invasion assay kit was used to quantify the invasive capacity of 786-O and Caki-2 cells. It was demonstrated that detachment from the ECM decreases transcription and the protein expression level of Tim-3 in 786-O and Caki-2 cells compared with control cells. Interference with Tim-3 expression using small interfering RNA exacerbated anoikis in 786-O and Caki-2 cells induced by poly-HEMA treatment. E-cadherin upregulation, N-cadherin downregulation, and ECM detachment-induced reduction in invasion ability were all exacerbated by knockdown of Tim-3. In conclusion, interference with Tim-3 expression may attenuate the invasion of renal cell carcinoma by aggravating anoikis, indicating Tim-3 as a potential therapeutic target for treating ccRCC. PMID:28112366

  16. Detection and mapping of volcanic rock assemblages and associated hydrothermal alteration with Thermal Infrared Multiband Scanner (TIMS) data Comstock Lode Mining District, Virginia City, Nevada

    Science.gov (United States)

    Taranik, James V.; Hutsinpiller, Amy; Borengasser, Marcus

    1986-01-01

    Thermal Infrared Multispectral Scanner (TIMS) data were acquired over the Virginia City area on September 12, 1984. The data were acquired at approximately 1130 hours local time (1723 IRIG). The TIMS data were analyzed using both photointerpretation and digital processing techniques. Karhuen-Loeve transformations were utilized to display variations in radiant spectral emittance. The TIMS image data were compared with color infrared metric camera photography, LANDSAT Thematic Mapper (TM) data, and key areas were photographed in the field.

  17. LITERASI MEDIA SEBAGAI STRATEGI KOMUNIKASI TIM SUKSES RELAWAN PEMENANGAN PEMILIHAN PRESIDEN JOKOWI JK DI BANDUNG

    Directory of Open Access Journals (Sweden)

    Annisa Senova

    2016-12-01

    Full Text Available Memahami kegiatan literasi media yang terjadi dalam kehidupan berorganisasi akan memberikan gambaran yang jelas tentang kemampuan mengidentifikasi, menentukan, mengorganisir, dan menggunakan media, serta menjadikan informasi sebagai bahan pertimbangan pembuatan keputusan tim sukses relawan pemenangan Presiden Joko Widodo dan Jusuf Kalla di Bandung. Oleh karena itu, penelitian ini dilakukan untuk menemukan kegiatan literasi media sebagai strategi komunikasi tim sukses relawan pemenangan pemilihan presiden Joko Widodo dan Jusuf Kalla. Metode yang digunakan dalam penelitian ini adalah metode kualitatif dengan pendekatan studi kasus. Penelitian ini menggunakan teknik pengumpulan data berupa wawancara mendalam, observasi, dan studi dokumentasi. Teknik pemeriksaan keabsahan data yang digunakan dalam penelitian ini adalah dengan triangulasi data sumber. Media sosial menjadi media utama dalam proses penyampaian pesan kepada khalayak di kota Bandung. Terdapat beberapa jenis media sosial yang akan digunakan secara rutin dalam proses tersebut, yaitu Twitter, Facebook, Instagram, dan Youtube. Namun, timses relawan media sosial hanya fokus kepada dua jenis media sosial yang dianggap dapat mempengaruhi pandangan publik. Twiter dan Instagram dianggap mampu menjadi jejaring sosial yang efektif dalam proses penyampaian pesan politik pemilu 2014. Penyampaian informasi oleh timses relawan media sosial kepada masyarakat melalui Twitter dan Instagram dianggap sangat efektif dan tepat. Konten-konten yang disediakan oleh akun Twitter sangat mudah untuk diakses oleh semua kalangan. Penelitian tantang proses literasi media tim sukses relawan pemenangan presiden Jokowi-Jk ini dapat menambah masukan bagi ilmu komunikasi, terutama dalam bidang literasi media, bahwa saat ini keberadaan media dapat menjadi sebuah strategi komunikasi yang cukup efektif.   DOI: 10.24198/jkk.vol4n2.3

  18. Ontology and anthropology of interanimality: Merleau-Ponty from Tim ingold's perspective

    Directory of Open Access Journals (Sweden)

    Ana Cristina Ramírez Barreto

    2010-01-01

    Full Text Available This essay explores Tim Ingold’s anthropological theory following his references to Merleau-Ponty and the concept of interanimality/interagentivity. It poses some ideas of Ingold’s “poetics of dwelling”, which he highlights from ethnographies of hunter-gatherer peoples, and how these ideas are linked to an ontological consideration which does not dissociate body and person, body and mind, nature and culture, animality and humanity. The paper reviews animal literature in Merleau-Ponty’s philosophy, and Ingold’s critique of “Anthropology of the senses”. It also gives critical clues for the ethical and political implications of this ontology.

  19. Second NASA Technical Interchange Meeting (TIM): Advanced Technology Lifecycle Analysis System (ATLAS) Technology Tool Box (TTB)

    Science.gov (United States)

    ONeil, D. A.; Mankins, J. C.; Christensen, C. B.; Gresham, E. C.

    2005-01-01

    The Advanced Technology Lifecycle Analysis System (ATLAS), a spreadsheet analysis tool suite, applies parametric equations for sizing and lifecycle cost estimation. Performance, operation, and programmatic data used by the equations come from a Technology Tool Box (TTB) database. In this second TTB Technical Interchange Meeting (TIM), technologists, system model developers, and architecture analysts discussed methods for modeling technology decisions in spreadsheet models, identified specific technology parameters, and defined detailed development requirements. This Conference Publication captures the consensus of the discussions and provides narrative explanations of the tool suite, the database, and applications of ATLAS within NASA s changing environment.

  20. A ANTROPOLOGIA COMO PARTICIPANTE DE UMA GRANDE CONVERSA PARA MOLDAR O MUNDO. ENTREVISTA COM TIM INGOLD

    OpenAIRE

    Mafra,Clara; Bonet,Octavio; Velho,Otávio; Prado,Rosane

    2014-01-01

    Resumo A entrevista enfatiza a perspectiva antropológica do Tim Ingold e seu modo particular de entender as relações ecológicas entre os organismos e o entorno. Para desvendar esta perspectiva o diálogo segue um percurso pelos anos de formação e pelas influencias teóricas do entrevistado, alem das relações com alguns pensadores das ciências humanas no contexto atual de produção do conhecimento.