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Sample records for prof qiang fu

  1. The Cultural Recreation of the Traditional Working and Living Appliances in Tibetan and Qiang Culture

    OpenAIRE

    Cen, Hua; Ma, Chuan Dong

    2014-01-01

    Confronting the contradiction of the global trend of cultural homogenization and the appeals for the independence of national culture, this paper put forwards the new design concept of “Green Humanity”. Guided by the “green humanity” philosophy, our research on the living and working appliances typical of Tibetan and Qiang people, and on the practice of the localization strategy of cultural recreation of Tibetan and Qiang culture would make our national culture more and more prosperous. It is...

  2. Rama, Prof.

    Indian Academy of Sciences (India)

    Elected: 1969 Section: Earth & Planetary Sciences. Rama, Prof. Ph.D. (Mumbai), FNA, FNAAS. Date of birth: 16 March 1929. Specialization: Isotope Hydrology Address: Y-4, Sector 9, CBD, Navi Mumbai 400 614, Maharashtra Contact: Residence: (022) 2757 0081. Email: rama139@yahoo.co.in. YouTube; Twitter; Facebook ...

  3. FuNNy

    DEFF Research Database (Denmark)

    Madsen, Per Printz

    2005-01-01

    The purpose of this paper is to describe a tool that is easy to use for implementing self learning fuzzy systems. This tool which is called FuNNy generates fuzzy systems. The tool consists of a compiler and a C learning library. The compiler translates a fuzzy system (written in a dedicated...... language, called FuNNy language) to C. The C learning library contains the learning algorithm. The generated C code is simple standard C and therefore it can be applied to all computers with a C-compiler. The learning algorithm is either a gradient descend method based on a numerical calculation...

  4. Study on Strata Behavior Regularity of 1301 Face in Thick Bedrock of Wei - qiang Coal Mine

    Science.gov (United States)

    Gu, Shuancheng; Yao, Boyu

    2017-09-01

    In order to ensure the safe and efficient production of the thick bedrock face, the rule of the strata behavior of the thick bedrock face is discussed through the observation of the strata pressure of the 1301 first mining face in Wei qiang coal mine. The initial face is to press the average distance of 50.75m, the periodic weighting is to press the average distance of 12.1m; during the normal mining period, although the upper roof can not be broken at the same time, but the pressure step is basically the same; the working face for the first weighting and periodical weighting is more obvious to the change of pressure step change, when the pressure of the working face is coming, the stent force increased significantly, but there are still part of the stent work resistance exceeds the rated working resistance, low stability, still need to strengthen management.

  5. Comparative study of bacterial status from conjunctival sac of the elder Qiang minority and Han people with dry eye in Sichuan, China.

    Science.gov (United States)

    Zhang, Yue; Liu, Zhi-Rong; Chen, Hui; Dong, Wan-Jiang; Fan, Ying-Chuan; Yu, Hua; Wang, Guang-Jin; Li, Yu-Chan; Cao, Kui

    2012-01-01

    To compare the status of bacteria in the conjunctival sac from the elder Qiang minority and Han people with dry eyes in Sichuan, China. Total of 54 elder Qiang people with dry eyes (108 eyes) were examined by cluster sampling. In the similar habitation region of Han people, 80 (160 dry eyes) Han people were analyzed as the control group. The bacteria was separated from the inferior palpebral conjunctiva, then inoculated on blood plate for 48 hours and identified. Totally 24 strains of bacteria were cultured in either Qiang minority or Han c populations with 3 strains of them existed in both ethnic groups. The commonest bacteria in conjunctival sac in two ethnic groups were non-pathogenic bacterium. The composition of Corynebacterium in Han people (54.1%) was significantly higher than that in Qiang minority (27.4%) (χ(2)=11.6721, P=0.0006). The percentage of Sphingomonas Paucimobilis in Qiang people was higher than that in Han people (χ(2)=18.6442, P=0.0000). However, there was no significant difference between Qiang minority and Han people either in bacterial positive rate in conjunctival sac, or the composition of bacteria species and strains, or the composition of staphylococcus epidemids between two ethnic populations. There was no significant difference of bacterial positive rate in conjunctival sac from the elder of Qiang minority and Han people with dry eye, but the species of bacteria were different.

  6. Marks, Prof. Tobin J

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2011 Honorary. Marks, Prof. Tobin J. Date of birth: 25 November 1944. Address: Prof. of Materials Sci. & Engg., Department of Chemistry, Northwestern University, 2145, Sheridan Road, Evanston, IL 60208, USA Contact: Office: (+1-847) 491 5658. Email: t-marks@northwestern.edu. YouTube; Twitter ...

  7. Porsezian, Prof. Kuppuswamy

    Indian Academy of Sciences (India)

    Porsezian, Prof. Kuppuswamy Ph.D. (Bharathidasan), FNASc. Date of birth: 5 June 1963. Specialization: Nonlinear Solitons, Bose-Einstein Condensates, Solitons, Modulational Instability, Nonlinear Fibre Optics, Partial Differential Equations Address: Department of Physics, Pondicherry University, Kalapet, Puducherry 605 ...

  8. Joffe, Prof. Abram Fiodorovich

    Indian Academy of Sciences (India)

    Academy Public Lecture. Posted on 19 January 2018. Seasonal and Pandemic Influenza by Prof. Kanta Subbarao 25 January 2018 at 1600 hrs. Ground floor, Main auditorium, New Biological Sciences Building, IISc. Event Poster ...

  9. Mark, Prof. Herman Francis

    Indian Academy of Sciences (India)

    Academy Public Lecture. Posted on 19 January 2018. Seasonal and Pandemic Influenza by Prof. Kanta Subbarao 25 January 2018 at 1600 hrs. Ground floor, Main auditorium, New Biological Sciences Building, IISc. Event Poster ...

  10. Dale, Prof. Henry Hallett

    Indian Academy of Sciences (India)

    Academy Public Lecture. Posted on 19 January 2018. Seasonal and Pandemic Influenza by Prof. Kanta Subbarao 25 January 2018 at 1600 hrs. Ground floor, Main auditorium, New Biological Sciences Building, IISc. Event Poster ...

  11. Jagadish, Prof. Chennupati

    Indian Academy of Sciences (India)

    Academy Public Lecture. Posted on 19 January 2018. Seasonal and Pandemic Influenza by Prof. Kanta Subbarao 25 January 2018 at 1600 hrs. Ground floor, Main auditorium, New Biological Sciences Building, IISc. Event Poster ...

  12. Pauli, Prof. Wolfgang Armst

    Indian Academy of Sciences (India)

    Academy Public Lecture. Posted on 19 January 2018. Seasonal and Pandemic Influenza by Prof. Kanta Subbarao 25 January 2018 at 1600 hrs. Ground floor, Main auditorium, New Biological Sciences Building, IISc. Event Poster ...

  13. Hopkins, Prof. Frederick Gowland

    Indian Academy of Sciences (India)

    Academy Public Lecture. Posted on 19 January 2018. Seasonal and Pandemic Influenza by Prof. Kanta Subbarao 25 January 2018 at 1600 hrs. Ground floor, Main auditorium, New Biological Sciences Building, IISc. Event Poster ...

  14. Burma, Prof. Debi Prosad

    Indian Academy of Sciences (India)

    , Prof. Debi Prosad D.Phil. (Calcutta), FNA, FNASc, FAMS. Date of birth: 1 February 1925. Date of death: 4 February 2005. Specialization: Biochemistry and Molecular Biology Last known address: CF 186, Sector I, Salt Lake City, Kolkata 700 ...

  15. Bhatia, Prof. Suresh Kumar

    Indian Academy of Sciences (India)

    Bhatia, Prof. Suresh Kumar Ph.D. (Pennsylvania). Date of birth: 8 September 1952. Specialization: Transport & Reaction in Nanostructured Porous Media, Adsorption and Mathematical Modelling Address: Professor, Department of Chemical Engineering, University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia

  16. Athreya, Prof. Krishna Balasundaram

    Indian Academy of Sciences (India)

    Elected: 1974 Section: Mathematical Sciences. Athreya, Prof. Krishna Balasundaram Ph.D. (Stanford). Date of birth: 12 December 1939. Specialization: Probability Theory, Stochastic Processes and Mathematical Statistics Address: Distinguished Professor Emeritus, Departments of Mathematics & Statistics, Iowa State ...

  17. Inamdar, Prof. Maneesha Shreedhar

    Indian Academy of Sciences (India)

    Inamdar, Prof. Maneesha Shreedhar Ph.D. (Bombay). Date of birth: 25 February 1967. Specialization: Stem Cell Biology, Cardiovascular Development, Hematopoiesis & Angiogenesis Address: Molecular Biology & Genetics Unit, JN Centre for Advanced Scientific Research, Jakkur, Bengaluru 560 064, Karnataka Contact:

  18. Mallik, Prof. Ranjan Kumar

    Indian Academy of Sciences (India)

    Academy Public Lecture. Posted on 19 January 2018. Seasonal and Pandemic Influenza by Prof. Kanta Subbarao 25 January 2018 at 1600 hrs. Ground floor, Main auditorium, New Biological Sciences Building, IISc. Event Poster ...

  19. Vishveshwara, Prof. Saraswathi

    Indian Academy of Sciences (India)

    Academy Public Lecture. Posted on 19 January 2018. Seasonal and Pandemic Influenza by Prof. Kanta Subbarao 25 January 2018 at 1600 hrs. Ground floor, Main auditorium, New Biological Sciences Building, IISc. Event Poster ...

  20. Bhargava, Prof. Manjul

    Indian Academy of Sciences (India)

    ACADEMY PUBLIC LECTURE: How Things Break – The Mechanics of Dynamic Fracture. Posted on 16th February 2018. by Prof. Krishnaswamy Ravi-Chandar. in Faculty Hall, Indian Institute of Science. on 23 February 2018, 1500 event poster ...

  1. Surolia, Prof. Namita

    Indian Academy of Sciences (India)

    Academy Public Lecture. Posted on 19 January 2018. Seasonal and Pandemic Influenza by Prof. Kanta Subbarao 25 January 2018 at 1600 hrs. Ground floor, Main auditorium, New Biological Sciences Building, IISc. Event Poster ...

  2. Chaudhari, Prof. Raghunath Vitthal

    Indian Academy of Sciences (India)

    Elected: 1992 Section: Engineering & Technology. Chaudhari, Prof. Raghunath Vitthal Ph.D. (Mumbai), FNA, FNAE. Date of birth: 17 April 1948. Specialization: Homogeneous and Heterogeneous Catalysis, Biomass Conversion; Multiphase Reactors, Chemical Reaction Engineering and Kinetics & Mechanism Address: ...

  3. Sankara Rao, Prof. Kolluri

    Indian Academy of Sciences (India)

    Sankara Rao, Prof. Kolluri Ph.D. (Bangalore). Date of birth: 15 December 1939. Specialization: Plant Developmental Biology, Biotechnology, Biodiversity Informatics & Plant Systematics Address: Distinguished Fellow, Centre for Ecological Sciences, Indian Institute of Science, Bengaluru 560 012, Karnataka Contact:

  4. Sarin, Prof. Manmohan

    Indian Academy of Sciences (India)

    Elected: 2000 Section: Earth & Planetary Sciences. Sarin, Prof. Manmohan Ph.D. (Gujarat), FNA, FNASc. Date of birth: 26 July 1951. Specialization: Atmospheric & Aerosol Chemistry and Chemical Oceanography Address: INSA Senior Scientist, Physical Research laboratory, Navarangpura, Ahmedabad 380 009, Gujarat

  5. Venkatesh, Prof. Kareenhalli Viswanath

    Indian Academy of Sciences (India)

    Elected: 2016 Section: Engineering & Technology. Venkatesh, Prof. Kareenhalli Viswanath Ph.D. (Purdue). Date of birth: 7 June 1967. Specialization: Biosystems Engineering, Synthetic Biology, Metabolic Engineering Address: Department of Chemical Engineering, Indian Institute of Technology, Powai, Mumbai 400 076, ...

  6. Bhattacharya, Prof. Santanu

    Indian Academy of Sciences (India)

    Elected: 2000 Section: Chemistry. Bhattacharya, Prof. Santanu Ph.D. (Rutgers), FNA, FTWAS. Date of birth: 23 April 1958. Specialization: Chemical Biology, Molecular Theranostics, Soft Materials, Supramolecular Analytical Chemistry, Nanoscience & Nanotechnology Address: Director, Indian Association for the Cultivation ...

  7. Krishnamoorthy, Prof. Guruswamy

    Indian Academy of Sciences (India)

    Elected: 2000 Section: General Biology. Krishnamoorthy, Prof. Guruswamy Ph.D. (Bombay), FNA. Date of birth: 10 May 1950. Specialization: Biophysical Chemistry, Laser Spectroscopy and Macromolecular Dynamics Address: Honorary Professor, Department of Biotechnology, Anna University, Guindy, Chennai 600 025, ...

  8. Rao, Prof. Madan

    Indian Academy of Sciences (India)

    Elected: 2011 Section: Physics. Rao, Prof. Madan Ph.D. (IISc). Date of birth: 11 July 1960. Specialization: Nonequilibrium Statistical Mechanics, Soft Condensed Matter Physics, Biological Physics Address: Theoretical Physics Group, Raman Research Institute, CV Raman Avenue, Bengaluru 560 080, Karnataka Contact:

  9. Pandit, Prof. Aniruddha Bhalachandra

    Indian Academy of Sciences (India)

    Pandit, Prof. Aniruddha Bhalachandra Ph.D. (Mumbai), FNAE, FNA, FNASc, FTWAS. Date of birth: 7 December 1957. Specialization: Design of Multiphase Reactors, Cavitation Phenomena and Environmental & Energy Engineering Address: Dean (HR), Institute of Chemical Technology, N.P. Marg, Matunga, Mumbai 400 ...

  10. Ganesh, Prof. Subramaniam

    Indian Academy of Sciences (India)

    Elected: 2016 Section: Medicine. Ganesh, Prof. Subramaniam Ph.D. (Banaras), FNASc. Date of birth: 23 May 1968. Specialization: Human Molecular Genetics, Neurobiology of Disease, Stress Biology Address: Department of Biological Sciences & Bioengineering, Indian Institute of Technology, Kanpur 208 016, U.P.

  11. Krishna, Prof. Padmanabhan

    Indian Academy of Sciences (India)

    Elected: 1979 Section: Physics. Krishna, Prof. Padmanabhan Ph.D. (Banaras), FNA. Date of birth: 13 January 1938. Specialization: Crystallography, Imperfection in Solids, Education and Science & Society Address: Adviser, Krishnamurti Foundation India, Rajghat Education Centre, Rajghat Fort, Varanasi 221 001, U.P.

  12. Dash, Prof. Debabrata

    Indian Academy of Sciences (India)

    Dash, Prof. Debabrata Ph.D. (BHU). Date of birth: 12 April 1958. Specialization: Cell Biology, Signal Transduction, Nanobiotechnology Address: Head, Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221 005, U.P.. Contact: Office: (0542) 670 3243. Residence: (0542) 236 9300

  13. Kumar, Prof. Har Darshan

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1975 Section: Plant Sciences. Kumar, Prof. Har Darshan Ph.D. (London), FNA, FNASc. Date of birth: 25 February 1934. Specialization: Algology, Microbial Biotechnology, Genetics, Ecology and Environment Address: Mrigtrishna, B.32/32, H.K. 214, Saketnagar Colony, Naria, Varanasi 221 005, U.P.

  14. Jayaraman, Prof. Achuthan

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2006 Section: Earth & Planetary Sciences. Jayaraman, Prof. Achuthan Ph.D. (Gujarat). Date of birth: 21 June 1957. Specialization: Atmospheric Science, Aerosols and Radiative Transfer Address: Director, National Atmospheric Research Laboratory, P. B. No. 123, Tirupati - 517 502, A.P.. Contact:

  15. Rangaswamy, Prof. Nanjangud Sreekantaiah

    Indian Academy of Sciences (India)

    Elected: 1981 Section: Plant Sciences. Rangaswamy, Prof. Nanjangud Sreekantaiah Ph.D. (Delhi), FNA, FNASc. Date of birth: 8 May 1932. Specialization: Reproductive Physiology of Seed Plants, Plant Tissue Culture and Biotechnology Address: Apt. No. 241, III Floor, Block B-2, Kendriya Vihar, Bellary Road, Yelahanka, ...

  16. Tyagi, Prof. Akhilesh Kumar

    Indian Academy of Sciences (India)

    Elected: 2004 Section: Plant Sciences. Tyagi, Prof. Akhilesh Kumar Ph.D. (Delhi), FNA, FNASc, FNAAS, FTWAS. Date of birth: 15 May 1956. Specialization: Genomics, Regulation Biology and Biotechnology Address: Department of Plant Molecular Biology, University of Delhi - South Campus, Benito Juarez Road, New Delhi ...

  17. Chakravorty, Prof. Animesh

    Indian Academy of Sciences (India)

    Elected: 1975 Section: Chemistry. Chakravorty, Prof. Animesh Ph.D. (Calcutta), FNA, FTWAS Council Service: 1986-91. Date of birth: 30 June 1935. Specialization: Inorganic Chemistry Address: Flat 8/3, 6, Sunny Park, Ballygunge, Kolkata 700 019, W.B.. Contact: Residence: (033) 2485 8327. Mobile: 94338 01715

  18. Krebs, Prof. Hans Adolf

    Indian Academy of Sciences (India)

    Krebs, Prof. Hans Adolf Nobel Laureate (Medicine) - 1953. Date of birth: 25 August 1900. Date of death: 22 November 1981. YouTube; Twitter ... Summer Schools. Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach.

  19. Pauling, Prof. Linus Carl

    Indian Academy of Sciences (India)

    Pauling, Prof. Linus Carl Nobel Laureate (Chemistry) - 1954; Peace - 1962. Date of birth: 28 February 1901. Date of death: 19 August 1994 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  20. Pavlov, Prof. Ivan Petrovich

    Indian Academy of Sciences (India)

    Pavlov, Prof. Ivan Petrovich Nobel Laureate (Medicine) - 1904. Date of birth: 27 September 1849. Date of death: 27 February 1936. YouTube ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  1. Hardy, Prof. Godfrey Harold

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1935 Honorary. Hardy, Prof. Godfrey Harold. Date of birth: 7 February 1877. Date of death: 1 December 1947 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  2. Richardson, Prof. Owen Willians

    Indian Academy of Sciences (India)

    Richardson, Prof. Owen Willians Nobel Laureate (Physics) - 1928. Date of birth: 26 April 1879. Date of death: 15 February 1959. YouTube ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  3. Brillouin, Prof. Leon

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1939 Honorary. Brillouin, Prof. Leon. Date of birth: 7 August 1889. Date of death: 4 October 1969 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  4. Rouxel, Prof. Jean

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1994 Honorary. Rouxel, Prof. Jean. Date of birth: 24 February 1935. Date of death: 19 March 1998 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  5. Segre, Prof. Emilio Gino

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1971 Honorary. Segre, Prof. Emilio Gino. Date of birth: 1 February 1905. Date of death: 22 April 1989. YouTube; Twitter ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  6. Karrer, Prof. Paul

    Indian Academy of Sciences (India)

    Elected: 1947 Honorary. Karrer, Prof. Paul Nobel Laureate (Chemistry) - 1937. Date of birth: 21 April 1889. Date of death: 18 June 1971 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  7. Lundsgaard, Prof. Einar

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1966 Honorary. Lundsgaard, Prof. Einar. Date of birth: 12 February 1899. Date of death: 18 December 1968. YouTube ... Summer Schools. Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach.

  8. Bragg, Prof. William Henry

    Indian Academy of Sciences (India)

    Elected: 1935 Honorary. Bragg, Prof. William Henry Nobel Laureate (Physics) - 1915. Date of birth: 2 July 1862. Date of death: 10 March 1972 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  9. Pitzer, Prof. Kenneth Sanborn

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1986 Honorary. Pitzer, Prof. Kenneth Sanborn. Date of birth: 6 January 1914. Date of death: 26 December 1997 ... Summer Schools. Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach.

  10. Kock, Prof. Winston E.

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1970 Honorary. Kock, Prof. Winston E. Date of birth: 5 December 1909. Date of death: 25 November 1982. YouTube ... Summer Schools. Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach.

  11. Rutherford, Prof. Ernest (Lord)

    Indian Academy of Sciences (India)

    Rutherford, Prof. Ernest (Lord) Nobel Laureate (Chemistry) - 1908. Date of birth: 30 August 1871. Date of death: 19 October 1937. YouTube ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  12. Bawden, Prof. Frederick Charles

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1972 Honorary. Bawden, Prof. Frederick Charles. Date of birth: 18 August 1908. Date of death: 8 February 1972 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  13. Bridgman, Prof. Percy Williams

    Indian Academy of Sciences (India)

    Bridgman, Prof. Percy Williams Nobel Laureate (Physics) - 1946. Date of birth: 21 April 1882. Date of death: 20 August 1961. YouTube; Twitter ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  14. Russell, Prof. John

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Russell, Prof. John. Date of birth: 31 October 1872. Date of death: 12 July 1965 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  15. Anderson, Prof. Basil Williams

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1964 Honorary. Anderson, Prof. Basil Williams. Date of birth: 3 July 1901. Date of death: 24 February 1984. YouTube ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  16. Bovet, Prof. Daniel

    Indian Academy of Sciences (India)

    Elected: 1967 Honorary. Bovet, Prof. Daniel Nobel Laureate (Medicine) - 1957. Date of birth: 23 March 1907. Date of death: 8 April 1992 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  17. Morgan, Prof. Thomas Hunt

    Indian Academy of Sciences (India)

    Morgan, Prof. Thomas Hunt Nobel Laureate (Medicine) - 1933. Date of birth: 25 September 1866. Date of death: 4 December 1945. YouTube ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  18. Mecke, Prof. Reinhard

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1957 Honorary. Mecke, Prof. Reinhard. Date of birth: 14 July 1895. Date of death: 30 December 1969. YouTube; Twitter ... Summer Schools. Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach.

  19. Kastler, Prof. Alfred

    Indian Academy of Sciences (India)

    Elected: 1970 Honorary. Kastler, Prof. Alfred Nobel Laureate (Physics) - 1966. Date of birth: 3 May 1902. Date of death: 7 January 1984 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  20. Bunning, Prof. Erwing

    Indian Academy of Sciences (India)

    Elected: 1986 Honorary. Bunning, Prof. Erwing. Date of birth: 23 January 1906. Date of death: 4 October 1990. YouTube; Twitter; Facebook ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  1. Chapman, Prof. Sydney

    Indian Academy of Sciences (India)

    Elected: 1947 Honorary. Chapman, Prof. Sydney. Date of birth: 29 January 1888. Date of death: 16 June 1970. YouTube; Twitter; Facebook ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  2. Plyler, Prof. Earle Keith

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1962 Honorary. Plyler, Prof. Earle Keith. Date of birth: 26 April 1897. Date of death: 8 May 1976 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  3. Bowen, Prof. Ira Sprague

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1956 Honorary. Bowen, Prof. Ira Sprague. Date of birth: 21 December 1898. Date of death: 6 February 1973. YouTube ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  4. Sebastian, Prof. Kizhakeyil Lukose

    Indian Academy of Sciences (India)

    Sebastian, Prof. Kizhakeyil Lukose Ph.D. (IISc), FNA Council Service: 2016-. Date of birth: 18 November 1950. Specialization: Theoretical Chemistry and Chemistry of Interfaces Address: Department of Chemistry, Indian Institute of Technology, Ahalia Integrated Campus, Kozhippara Post, Palakkad 678 557, Kerala Contact:

  5. Indira Nath, Prof.

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1988 Section: Medicine. Indira Nath, Prof. M.D. (AIIMS), FRC Path., FAMS, FNA, FNASc, D.Sc. (h.c.) Council Service: 1992-94, 1998-2006; Vice-President 2001-2003. Date of birth: 14 January 1938. Specialization: Immunology, Leprosy and Pathology Address: 707, Sarvapriya ...

  6. Majumder, Prof. Partha Pratim

    Indian Academy of Sciences (India)

    Majumder, Prof. Partha Pratim Ph.D. (ISI, Calcutta), FNA, FNASc, FTWAS Council Service: 2016-. Date of birth: 6 September 1952. Specialization: Biostatistics, Human Genetics and Population Genetics Address: Distinguished Professor, National Institute of Biomedical Genomics, Post Netaji Subhas Sanitorium, Kalyani 741 ...

  7. Chandrashekaran, Prof. Maroli Krishnayya

    Indian Academy of Sciences (India)

    Chandrashekaran, Prof. Maroli Krishnayya Ph.D. (Madras), D.Sc. (Madurai), FNA, FNASc, FTWAS Council Service: 1992-97. Date of birth: 4 January 1937. Date of death: 2 July 2009. Specialization: Chronobiology and Animal Behaviour Last known address: Evolutionary and Organismal Biology Unit, Jawaharlal Nehru ...

  8. Adiga, Prof Perdur Radhakantha

    Indian Academy of Sciences (India)

    Adiga, Prof Perdur Radhakantha Ph.D. (IISc), FNA. Date of birth: 5 May 1935. Date of death: 13 September 2006. Specialization: Endocrine Biochemistry, Reproductive Physiology & Growth, and Differentiation Last known address: Emeritus Professor, Department of Molecular Reproduction and Developmental, Genetics, ...

  9. Bhattacharjee, Prof. Somendra Mohan

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2000 Section: Physics. Bhattacharjee, Prof. Somendra Mohan Ph.D. (Carnegie Mellon), FNA. Date of birth: 24 January 1957. Specialization: Statistical Physics and Condensed Matter Physics Address: Institute of Physics, Sachivalaya Marg, Bhubaneswar 751 005, Orissa Contact:

  10. Agarwal, Prof Girish S

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  11. Aswathanarayana, Prof. Uppugunduri

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1976 Section: Earth & Planetary Sciences. Aswathanarayana, Prof. Uppugunduri D.Sc. (Andhra), FNA, FTWAS. Date of birth: 1 July 1928. Date of death: 7 March 2016. Specialization: Nuclear Geology, Natural Resources Management and Environmental Geochemistry Last known address: Shanti ...

  12. Mishra, Prof. Santosh Kumar

    Indian Academy of Sciences (India)

    Elected: 1987 Section: Earth & Planetary Sciences. Mishra, Prof. Santosh Kumar Ph.D. (Pune), FNA. Date of birth: 1 March 1941. Specialization: Dynamic Meteorology and Numerical Modelling of the Atmosphere Address: Flat No. 4, 163/24 Mausam Vihar, Park Avenue, Off DP Road, Aundh, Pune 411 007, Maharashtra

  13. Gadgil, Prof. Sulochana

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1985 Section: Earth & Planetary Sciences. Gadgil, Prof. Sulochana Ph.D. (Harvard), FNA. Date of birth: 7 June 1944. Specialization: Meteorology, Oceanography and Evolutionary Biology Address: A 18, Spring Flowers, Panchavati, Pashan, Pune 411 008, Maharashtra Contact:

  14. Bhattacharyya, Prof. Prabhat Kumar

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1976 Section: Chemistry. Bhattacharyya, Prof. Prabhat Kumar Ph.D. (Illinois), FNA. Date of birth: 22 October 1921. Date of death: 16 April 1996. Specialization: Bio-organic Chemistry and Chemical Microbiology Address: 177, Jodhpur Park, Flat - 1S, Calcutta 700 068. YouTube; Twitter; Facebook ...

  15. Panda, Prof. Sudhakar

    Indian Academy of Sciences (India)

    Panda, Prof. Sudhakar Ph.D. (IoP, Bhubaneswar), FNA, FNASc. Date of birth: 23 February 1959. Specialization: High Energy Physics, String Theory, Cosmology, Quantum Field Theory Address: Director, Institute of Physics, Sachivalaya Marg, Bhubaneswar 751 005, Orissa Contact: Office: (0674) 230 1825, 230 6404

  16. Narayan, Prof. Ramesh

    Indian Academy of Sciences (India)

    Narayan, Prof. Ramesh FRS. Date of birth: 25 September 1950. Address: Harvard Smithsonian Centre for, Astrophysics, Harvard University, 60, Garden Street, MS-51, Cambridge, MA 02138, USA Contact: Office: (+1-617) 496 9393. Fax: (+1-617) 495 7053. Email: rnarayan@cfa.harvard.edu. YouTube; Twitter; Facebook ...

  17. Nicolaou, Prof. Kyriacos Costa

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2007 Honorary. Nicolaou, Prof. Kyriacos Costa. Date of birth: 1946. Address: Department of Chemistry & BRC, Rice University, 6100, Main Street, MS 602, Houston, TX 77005, U.S.A.. Contact: Residence: (+1-713) 348 8860. Fax: (+1-713) 348 8865. Email: kcn@rice.edu. YouTube; Twitter; Facebook ...

  18. Bai, Prof. Chunli

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2009 Honorary. Bai, Prof. Chunli. Date of birth: 1953. Address: Executive Vice-President, Chinese Academy of Sciences, 52, Sanlihe Road, Beijing 100864, China Contact: Office: (+86-10) 6859 7606. Fax: (+86-10) 6852 6316. Email: clbai@cas.cn. YouTube; Twitter; Facebook ...

  19. Chakravarty, Prof. Charusita

    Indian Academy of Sciences (India)

    Chakravarty, Prof. Charusita Ph.D. (Cambridge). Date of birth: 5 May 1964. Date of death: 29 March 2016. Specialization: Chemical Physics, Theoretical & Computational Chemistry Last known address: Professor, Department of Chemistry, Indian Institute of Technology, New Delhi 110 016, U.T.. YouTube; Twitter; Facebook ...

  20. Bloembergen, Prof. Nicolaas

    Indian Academy of Sciences (India)

    Bloembergen, Prof. Nicolaas Nobel Laureate (Physics) - 1981. Date of birth: 11 March 1920. Address: Optical Sciences Center, University of Arizona, 1630E, University Blvd., Tucson, AZ 85721, U.S.A.. Contact: Residence: (+1-520) 647 3772. Email: nbloembergen@optics.arizona.edu. YouTube; Twitter; Facebook; Blog ...

  1. Gross, Prof. David J

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2007 Honorary. Gross, Prof. David J. Date of birth: 1941. Address: Kavli Institute for Theoretical, Physics, University of California, Santa Barbara, CA 93106-4030, U.S.A.. Contact: Office: (+1-805) 893 7337. Residence: (+1-805) 963 8324. Fax: (+1-893) 893 2431. Email: gross@kitp.ucsb.edu. YouTube ...

  2. Hartl, Prof. Daniel L

    Indian Academy of Sciences (India)

    Hartl, Prof. Daniel L. Date of birth: 1 January 1943. Address: Higgins Professor of Biology, Dept. of Organismic & Evolutionary, Biology, The Biological Lab., Harvard University, 16 Divinity Ave, Cambridge, MA 02138, USA Contact: Office: (+1-617) 496 3917. Email: dhartl@oeb.harvard.edu. YouTube; Twitter; Facebook; Blog ...

  3. Hagenmuller, Prof. Paul

    Indian Academy of Sciences (India)

    Hagenmuller, Prof. Paul. Date of birth: 3 August 1921. Address: Honorary Director, ICMCB-CNRS, Bordeaux University, 87 Avenue Dr Albert Schweitzer, 33608 Pessac Cedex, France Contact: Office: (+33-5) 40 00 63 25. Fax: (+33-5) 40 00 63 24. Email: hagen@icmcb.u-bordeaux.fr. YouTube; Twitter; Facebook; Blog ...

  4. Venkataramana, Prof. Tyakal Nanjundiah

    Indian Academy of Sciences (India)

    Venkataramana, Prof. Tyakal Nanjundiah Ph.D. (Mumbai), FNA. Date of birth: 14 February 1958. Specialization: Monodromy Groups, Rigidity & Arithmeticity of Lattices, Cohomology of Arithmetic Groups and Shimura Varieties Address: Professor, School of Mathematics, Tata Institute of Fundamental Research, Homi Bhabha ...

  5. Bhattacharyya, prof. Tirthankar

    Indian Academy of Sciences (India)

    Elected: 2016 Section: Mathematical Sciences. Bhattacharyya, prof. Tirthankar Ph.D. (ISI). Date of birth: 7 February 1968. Specialization: Functional Analysis, Hilbert Space, Operator Theory, Several Complex Variables Address: Department of Mathematics, Indian Institute of Science, Bengaluru 560 012, Karnataka Contact:

  6. Nadkarni, Prof. Mahendra Ganpatrao

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1989 Section: Mathematical Sciences. Nadkarni, Prof. Mahendra Ganpatrao Ph.D. (Brown), FNA. Date of birth: 17 January 1939. Specialization: Ergodic Theory and Commutative Harmonic Analysis Address: Emeritus Professor, Department of Mathematics, University of Bombay, Vidyanagari, Kalina, ...

  7. Rajan, Prof. Conjeeveram Srirangachari

    Indian Academy of Sciences (India)

    Rajan, Prof. Conjeeveram Srirangachari Ph.D. (Bombay), FNA. Date of birth: 21 May 1961. Specialization: Automorphic Forms, Arithmetic Geometry and Representation Theory Address: Professor, School of Mathematics, Tata Institute of Fundamental Research, Homi Bhabha Road, Mumbai 400 005, Maharashtra Contact:

  8. Bhattacharyya, Prof. Kankan

    Indian Academy of Sciences (India)

    Bhattacharyya, Prof. Kankan Ph.D. (Calcutta), FNA, FNASc, FTWAS. Date of birth: 17 November 1954. Specialization: Femtosecond Laser Spectroscopy, Single Molecule Spectroscopy Address: Department of Chemistry, Indian Institute of Science Education & Research, Bypass Road, Bhauri, Bhopal 462 066, M.P.. Contact:

  9. Ananthakrishnan, Prof. Taracad Narayanan

    Indian Academy of Sciences (India)

    Ananthakrishnan, Prof. Taracad Narayanan Ph.D. and D.Sc. (Madras), FNA, FNAAS Council Service: 1980-82. Date of birth: 15 December 1925. Date of death: 7 August 2015. Specialization: Entomology, Cecidology and Chemical Ecology Last known address: 4312, Zenith Avenue South, Minneapolis, MN 55410, USA.

  10. Einstein, Prof. Albert

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1936 Honorary. Einstein, Prof. Albert Nobel Laureate (Physics) - 1921. Date of birth: 14 March 1879. Date of death: 18 April 1955. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science ...

  11. Anand, Prof. Anuranjan

    Indian Academy of Sciences (India)

    Elected: 2011 Section: Medicine. Anand, Prof. Anuranjan Ph.D. (IISc), FNASc, FNA. Date of birth: 5 April 1965. Specialization: Human Genetics & Genomics, Neurogenetics, Developmental Genetics Address: Molecular Biology & Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bengaluru ...

  12. Rajaraman, Prof. Vaidyeswaran

    Indian Academy of Sciences (India)

    Rajaraman, Prof. Vaidyeswaran S.M. (MIT), Ph.D. (Wisconsin), FNA, FNAE, FNASc. Date of birth: 8 September 1933. Specialization: Computer Science and Information Systems Design Address: Honorary Professor, Supercomputer Education and Research Centre, Indian Institute of Science, Bengaluru 560 012, Karnataka

  13. Das, Prof. Prosad Kumar

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1975 Section: Earth & Planetary Sciences. Das, Prof. Prosad Kumar D.Phil. (Calcutta), FNA Council Service: 1980-82. Date of birth: 20 May 1926. Date of death: 14 January 2011. Specialization: Numerical Weather Prediction, Ocean-Atmosphere Coupling, Storm Surges and Dynamic Meteorology

  14. Blumberg, Prof. Baruch Samuel

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1987 Honorary. Blumberg, Prof. Baruch Samuel Nobel Laureate (Medicine) - 1976. Date of birth: 28 July 1925. Date of death: 5 April 2011. Last known address: Distinguished Scientist, Fox Chase Cancer Center, 333, Cottman Avenue, Philadelphia, PA 19111, U.S.A.. YouTube; Twitter; Facebook ...

  15. Bhattacharya, Prof. Alok

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2015 Section: General Biology. Bhattacharya, Prof. Alok Ph.D. (JNU), FNA. Date of birth: 2 February 1951. Specialization: Molecular Parasitology, Computational Genomics Address: School of Life Sciences, Jawaharlal Nehru University, New Delhi 110 067, U.T.. Contact: Office: (011) 2670 4516

  16. Sharma, Prof. Man Mohan

    Indian Academy of Sciences (India)

    Sharma, Prof. Man Mohan Ph.D. (Cantab), D.Sc. (h.c.), D.Engg. (h.c.), LL.D. (h.c.), FNA, FRS Council Service: 1986-88. Date of birth: 1 May 1937. Specialization: Multiphase Reactions/Reactors, Separations Address: 2/3, Jaswant Baug, Behind Akbarallys, V.N. Purav Marg, Chembur, Mumbai 400 071, Maharashtra Contact:

  17. Ramakrishnan, Prof. Palayanoor Sivaswamy

    Indian Academy of Sciences (India)

    Ramakrishnan, Prof. Palayanoor Sivaswamy Ph.D. (Banaras), FNA, FNASc, FTWAS. Date of birth: 24 December 1936. Specialization: Socio-ecology, Environment and Sustainable Development Address: INSA Honorary Scientist, School of Environmental Sciences, Jawaharlal Nehru University, New Delhi 110 067, U.T.

  18. Punniyamurthy, Prof. Tharmalingam

    Indian Academy of Sciences (India)

    Punniyamurthy, Prof. Tharmalingam Ph.D. (IIT, Kanpur), FRSC. Date of birth: 3 June 1964. Specialization: Synthetic Organic Chemistry Address: Department of Chemistry, Indian Institute of Technology, Guwahati 781 039, Assam Contact: Office: (0361) 258 2309. Residence: (0361) 258 4309. Mobile: 94351 02462

  19. Chowdhury, Prof. Debashish

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2004 Section: Physics. Chowdhury, Prof. Debashish Ph.D. (IIT, Kanpur), FNASc, FNA. Date of birth: 10 September 1957. Specialization: Statistical Physics, Condensed Matter Physics and Biological Physics Address: Professor, Department of Physics, Indian Institute of Technology, ...

  20. Gadre, Prof. Shridhar Ramchandra

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1991 Section: Chemistry. Gadre, Prof. Shridhar Ramchandra Ph.D. (IIT, Kanpur), FNA. Date of birth: 20 May 1950. Specialization: Quantum Chemistry and Computer Applications Address: Interdisciplinary School of Scientific Computing, University of Pune, Ganeshkhind, Pune 411 007, Maharashtra

  1. Marimuthu, Prof. Ganapathy

    Indian Academy of Sciences (India)

    Marimuthu, Prof. Ganapathy Ph.D. (MKU), D.Sc. (MKU), FNASc, FNA. Date of birth: 25 February 1954. Specialization: Animal Behaviour and Chronobiology Address: INSA Senior Scientist, Department of Animal Behaviour and Physiology, School of Biological Sciences, Madurai Kamaraj University, Madurai 625 021, T.N.

  2. Sarkar, Prof. Chitra

    Indian Academy of Sciences (India)

    Sarkar, Prof. Chitra M.B.B.S. (Bangalore), M.D. (AIIMS), FRC Path. (London), FNASc, FAMS, FNA Council Service: 2013-15. Date of birth: 11 September 1955. Specialization: Neuropathology Address: Professor, Department of Pathology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, U.T.. Contact:

  3. Ramakrishna, Prof. Balakrishnan Siddartha

    Indian Academy of Sciences (India)

    Ramakrishna, Prof. Balakrishnan Siddartha MD, DM & Ph.D. (Madras), FAMS, FNA. Date of birth: 26 October 1952. Specialization: Gastroenterology, Nutrition, Inflammatory Bowel Disease, Gastrointestinal Microbiome Stem Cells Address: Flat No. 202-2-03, GVSPL Green Park, 342, Vaidyanathan Street, Nungambakkam, ...

  4. Radhakrishnan, Prof. Jaikumar

    Indian Academy of Sciences (India)

    Radhakrishnan, Prof. Jaikumar Ph.D. (Rutgers), FNA. Date of birth: 30 May 1964. Specialization: Algorithms, Information Theory, Computational Complexity, Combinatorics and Quantum Computing Address: Professor, School of Technology & Computer Science, Tata Institute of Fundamental Research, Homi Bhabha Road, ...

  5. Radhakrishnan, Prof. Thavarool Puthiyedath

    Indian Academy of Sciences (India)

    Radhakrishnan, Prof. Thavarool Puthiyedath Ph.D. (Princeton), FNA, FNASc. Date of birth: 25 May 1960. Specialization: Materials Chemistry Address: Professor, School of Chemistry, University of Hyderabad, Hyderabad 500 046, A.P.. Contact: Office: (040) 2313 4827, (040) 2301 1068. Residence: (040) 2980 2989

  6. Chakravarti, Prof. Aravinda

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2008 Honorary. Chakravarti, Prof. Aravinda. Date of birth: 6 February 1954. Address: Director - CCDG, McKusick-Nathans Inst. of Genetic, Medicine, Johns Hopkins Univ., School of Medicine, 733 N.Broadway, Baltimore, MD 21205, USA Contact: Office: (+1-410) 502 7525. Fax: (+1-410) 502 7544

  7. Ganeshaiah, Prof. Kotiganahalli Narayanagowda

    Indian Academy of Sciences (India)

    Elected: 1992 Section: Plant Sciences. Ganeshaiah, Prof. Kotiganahalli Narayanagowda Ph.D. (UAS, Bangalore), FNA, FNAAS. Date of birth: 10 May 1953. Specialization: Plant Evolutionary Biology, Plant Genetics & Breeding, Foraging Ecology of Ants and Biodiversity & Conservation Address: 7, Pungavee Santosh Vihar, ...

  8. Ananthakrishnan, Prof. Ramakrishnaiyer

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1938 Section: Earth & Planetary Sciences. Ananthakrishnan, Prof. Ramakrishnaiyer D.Sc. (Madras), FNA 1962-64. Date of birth: 11 April 1911. Date of death: 21 July 1998. Specialization: Solar Physics and Atmospheric Physics Address: Flat No. 9, Praram Apartments, Lakaki Road, Pune 411 016.

  9. Moorthy, Prof. Jarugu Narasimha

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2010 Section: Chemistry. Moorthy, Prof. Jarugu Narasimha Ph.D. (IISc). Date of birth: 1 July 1964. Specialization: Organic Photochemistry, Supramolecular Chemistry, Organic Synthesis Address: Department of Chemistry, Indian Institute of Technology, Kanpur 208 016, U.P.

  10. Ramasesha, Prof. Suryanarayana Sastry

    Indian Academy of Sciences (India)

    Ramasesha, Prof. Suryanarayana Sastry Ph.D. (IIT, Kanpur), FNA, FTWAS. Date of birth: 16 January 1950. Specialization: Many-Body Quantum Chemistry, Organic Solids, Molecular Electronics, Molecular Magnetism and Nonlinear Optics Address: Professor, Solid State & Structural Chemistry Unit, Indian Institute of Science ...

  11. Sankararaman, Prof. Sethuraman

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2017 Section: Chemistry. Sankararaman, Prof. Sethuraman Ph.D. (Victoria). Date of birth: 15 October 1957. Specialization: Organometallic Chemistry, Organic Photochemistry, Time-resolved Spectroscopy Address: Department of Chemistry, Indian Institute of Technology, Chennai 600 036, T.N.

  12. Vanninathan, Prof. Muthusamy

    Indian Academy of Sciences (India)

    Elected: 1997 Section: Mathematical Sciences. Vanninathan, Prof. Muthusamy Ph.D. (Pierre et Marie Curie, Paris). Date of birth: 15 May 1951. Specialization: Fluid-Structure Interactions, Partial Differential Equations, Numerical Analysis, Asymptotic Analysis, Homogenization and Control of PDE Address: Department of ...

  13. Sane, Prof. Sharad Sadashiv

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2010 Section: Mathematical Sciences. Sane, Prof. Sharad Sadashiv Ph.D. (IIT, Bombay). Date of birth: 20 November 1950. Specialization: Finite Geometries, Design Theory and Graph Theory Address: Department of Mathematics, Indian Institute of Technology, Powai, Mumbai 400 076, Maharashtra

  14. Bhosle, Prof. Ushadevi Narendra

    Indian Academy of Sciences (India)

    Elected: 2000 Section: Mathematical Sciences. Bhosle, Prof. Ushadevi Narendra Ph.D. (Bombay), FNASc, FNA. Date of birth: 30 March 1949. Specialization: Algebraic Geometry Address: Flat No. 256, Jal Vayu Towers, NGEF Layout, Bennigannahalli, Bengaluru 560 038, Karnataka Contact: Residence: 99306 41136

  15. Johri, Prof. Man Mohan

    Indian Academy of Sciences (India)

    Elected: 1983 Section: General Biology. Johri, Prof. Man Mohan Ph.D. (Delhi), FNA. Date of birth: 15 September 1940. Specialization: Plant Biochemistry, Molecular Biology of Plants and Genetic Engineering Address: Flat No. 32, New Cosmos CHSL, Juhu-Versova Link Road, Andheri (W), Mumbai 400 053, Maharashtra

  16. Khare, Prof. Avinash Vasant

    Indian Academy of Sciences (India)

    Elected: 1991 Section: Physics. Khare, Prof. Avinash Vasant Ph.D. (Calcutta), FNA. Date of birth: 20 June 1945. Specialization: High Energy & Elementary Particle Physics, Supersymmetric Quantum Mechanics and Nonlinear Dynamics Address: INSA Senior Scientist, Department of Physics, University of Pune, Ganeshkhind ...

  17. Narasimhan, Prof. Mudumbai Seshachalu

    Indian Academy of Sciences (India)

    Narasimhan, Prof. Mudumbai Seshachalu Ph.D. (Mumbai), FNA, FNASc, FRS Council Service: 1977-82; Vice-President: 1980-82. Date of birth: 7 June 1932. Specialization: Algebraic & Differential Geometry and Analysis Address: 9, Guruparadise Apartments, 24, 4th Main Road, Amarjyoti Layout, Sanjay Nagar, Bengaluru ...

  18. Ila, Prof. Hiriyakkanavar

    Indian Academy of Sciences (India)

    Elected: 1991 Section: Chemistry. Ila, Prof. Hiriyakkanavar Ph.D. (IIT, Kanpur), FNA. Date of birth: 11 September 1944. Specialization: Synthetic Organic Chemistry, Heterocyclic Chemistry, Medicinal Chemistry Address: Apt. 002, Block VIII, Heritage Estate, Doddaballapur Road, Yelahanka, Bengaluru 560 064, Karnataka

  19. Kulkarni, Prof. Sulabha Kashinath

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2004 Section: Physics. Kulkarni, Prof. Sulabha Kashinath Ph.D. (Pune), FNASc, FNA. Date of birth: 1 June 1949. Specialization: Surface Physics, Materials Science and Nanoscience Address: Centre for Materials for Electronics Technology, Off Dr Homi Bhabha Road, Panchwati, ...

  20. About Prof. Satish Dhawan

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 8; Issue 10. About Prof. Satish Dhawan. K Kasturirangan. General Article Volume 8 Issue 10 October 2003 pp 48-55. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/008/10/0048-0055. Keywords.

  1. Menon, Prof. Thuppalay Kochugovinda

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1974 Section: Physics. Menon, Prof. Thuppalay Kochugovinda Ph.D. (Harvard). Date of birth: 19 December 1928. Specialization: Astrophysics Address: 106-2803, 41st Avenue, Vancouver, British Columbia V6N 4B4, Canada Contact: Office: (+1-604) 822 0330. Residence: (+1-604) 266 1789

  2. Chander, Prof. Ramesh

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1993 Section: Earth & Planetary Sciences. Chander, Prof. Ramesh Ph.D. (Columbia). Date of birth: 6 September 1939. Specialization: Seismology and Geophysics Address: House No. 290, Sector 4, Mansa Devi Complex, Panchkula 134 114, Haryana Contact: Residence: (0172) ...

  3. Ramachandran, Prof. Arcot

    Indian Academy of Sciences (India)

    Elected: 1974 Section: Engineering & Technology. Ramachandran, Prof. Arcot Ph.D. (Purdue), D.Sc. (h.c.), D.lng. (h.c.), D.Eng. (h.c.), FNA, FNAE. Date of birth: 6 April 1923. Specialization: Energy, Heat and Mass Transfer Address: No. 3, Crescent Road, Bengaluru 560 001, Karnataka Contact: Residence: (080) 2225 5780

  4. Ramachandran, Prof. Raghavan

    Indian Academy of Sciences (India)

    Ramachandran, Prof. Raghavan Ph.D. (Chicago), FNASc. Date of birth: 15 February 1940. Specialization: Particle Physics Address: Flat 12, Khagol Society, Panchvati, Pashan, Pune 411 008, Maharashtra Contact: Residence: (020) 6607 5892. Mobile: 94220 04597. Email: rr_1940@yahoo.co.in, rr@imsc.res.in. YouTube ...

  5. Bose, Prof. Sujit Kumar

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1990 Section: Mathematical Sciences. Bose, Prof. Sujit Kumar D.Sc. (Calcutta). Date of birth: 10 October 1938. Specialization: Applied Mathematics, Solid Mechanics, Fluid Mechanics and Sediment Transport Address: BE-188, Salt Lake City, Kolkata 700 064, W.B.. Contact: Residence: 79805 77636

  6. Mahadevan, Prof. Priya

    Indian Academy of Sciences (India)

    Elected: 2014 Section: Physics. Mahadevan, Prof. Priya Ph.D. (IISc). Date of birth: 19 August 1970. Specialization: Electronic Structure of Materials, Magnetism, Nanostructure Materials Address: Associate Professor, SN Bose National Centre for Basic Sciences, JD Block, Sector 3, Salt Lake, Kolkata 700 098, W.B.. Contact:

  7. Sutherland, Prof. Bill

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2000 Honorary. Sutherland, Prof. Bill. Date of birth: 1942. Address: Department of Physics, University of Utah, 115 S 1400 E Rm 201, Salt Lake City, UT 8412-0830, U.S.A.. Contact: Office: (+1-801) 581 6424. Residence: (+1-801) 355 8342. Fax: (+1-801) 581 4801. Email: suther@physics.utah.edu, ...

  8. Rao, Prof. Sumathi

    Indian Academy of Sciences (India)

    Rao, Prof. Sumathi Ph.D. (SUNY, Stony Brook), FNASc. Date of birth: 5 December 1956. Specialization: Theoretical Condensed Matter Physics, Quantum field Theory Address: Harish Chandra Research Institute, Chhatnag Road, Jhusi, Allahabad 211 019, U.P.. Contact: Office: (0532) 227 4303. Residence: (0532) 227 4002

  9. Balaji, Prof. Vikraman

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2007 Section: Mathematical Sciences. Balaji, Prof. Vikraman Ph.D. (Madras). Date of birth: 15 September 1962. Specialization: Algebraic Geometry, Representation Theory and Topology Address: Chennai Mathematical Institute, H1, Sipcot IT Park, Padur Post, Siruseri, Chennai 603 103, T.N.. Contact ...

  10. Venkataraman, Prof. Ganesan

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  11. Vankar, Prof. Yashwant Dattatraya

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  12. Bapat, Prof. Ravindra Bhalchandra

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  13. Kodiyalam, Prof. Vijay

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  14. Goswami, Prof. Sreebrata

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  15. Ghosh, Prof. Sundargopal

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  16. Parthasarathy, Prof. Kalyanapuram Rangachari

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  17. Dasgupta, Prof. Indranil

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  18. Pontocorvo, Prof. Goido

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1984 Honorary. Pontocorvo, Prof. Goido. Date of birth: 29 November 1907. Date of death: 25 September 1999. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. New Fellows and Honorary Fellow. Posted on 1 January 2018. List of Fellows and Honorary Fellow elected ...

  19. Haddon, Prof. Alfred Cort

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1936 Honorary. Haddon, Prof. Alfred Cort. Date of birth: 24 May 1855. Date of death: 20 April 1940. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. New Fellows and Honorary Fellow. Posted on 1 January 2018. List of Fellows and Honorary Fellow elected during ...

  20. Ghosh, Prof. Anish

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2018 Section: Mathematical Sciences. Ghosh, Prof. Anish Ph.D. (Brandeis). Date of birth: 25 December 1979. Specialization: Ergodic Theory, Lie Groups, Number Theory Address: School of Mathematics, Tata Institute of Fundamental Research, Homi Bhabha Road, Mumbai 400 005, Maharashtra

  1. Prasad, Prof. Dipendra

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1995 Section: Mathematical Sciences. Prasad, Prof. Dipendra Ph.D. (Harvard), FNA, FNASc. Date of birth: 22 March 1960. Specialization: Automorphic Forms and Number Theory Address: Distinguished Professor, School of Mathematics, Tata Institute of Fundamental Research, Homi Bhabha Road, ...

  2. Khare, Prof. Avinash

    Indian Academy of Sciences (India)

    Khare, Prof. Avinash Ph.D. (PRL), FNA, FNASc. Date of birth: 23 July 1954. Specialization: Plasma Physics, Statistical Mechanics, Critical Phenomena, Plasma Astrophysics Address: Department of Physics & Astrophysics, University of Delhi, Delhi 110 007, U.T.. Contact: Office: (011) 2766 7155. Residence: (011) 2766 6242

  3. Mahapatra, Prof. Souvik

    Indian Academy of Sciences (India)

    Elected: 2018 Section: Engineering & Technology. Mahapatra, Prof. Souvik Ph.D. (IIT, Mumbai), FNAE, FIEEE. Date of birth: 26 October 1970. Specialization: Microelectronics & VLSI, Semiconductor Devices, Device Circuit Reliability Address: Department of Electrical Engineering, Indian Institute of Technology, Powai, ...

  4. Sane, Prof. Sanjay Prafullachandra

    Indian Academy of Sciences (India)

    Sane, Prof. Sanjay Prafullachandra Ph.D. (Univ. Calif., Berkeley). Date of birth: 12 September 1970. Specialization: Neuroethology, Biomechanics, Fluid Mechanics Address: National Centre for Biological Sciences, GKVK Campus, Bengaluru 560 065, Karnatka Contact: Office: (080) 2366 7020. Residence: (080) 4097 0586

  5. Bhargava, Prof. Balram

    Indian Academy of Sciences (India)

    Elected: 2018 Section: Medicine. Bhargava, Prof. Balram MD & DM (Lucknow), FNASc, FAMS, FRCP. Date of birth: 21 July 1961. Specialization: Cardiology, Medtech Innovation, Public Health Address: Department of Cardiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, U.T.. Contact:

  6. Sharma, Prof. Archana

    Indian Academy of Sciences (India)

    Annual Meetings · Mid Year Meetings · Discussion Meetings · Public Lectures · Lecture Workshops · Refresher Courses · Symposia · Live Streaming. Home; Fellowship. Fellow Profile. Elected: 1977 Section: Plant Sciences. Sharma, Prof. Archana Ph.D., D.Sc. (Calcutta), FNA, FNASc. Date of birth: 16 February 1932

  7. Prof. Dipankar Chatterji

    Indian Academy of Sciences (India)

    Elected: 1994 Section: General Biology. Chatterji, Prof. Dipankar Ph.D. (IISc), FNA, FNASc, FTWAS Council Service: 2007-; Secretary 2010-12; President: 2013-2015. Date of birth: 20 April 1951. Specialization: Molecular Biology, Biophysical Chemistry and Biomolecular Spectroscopy Address: Honorary Professor ...

  8. Shaila, Prof. Melkote Subbarao

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1993 Section: General Biology. Shaila, Prof. Melkote Subbarao Ph.D. (IISc). Date of birth: 10 October 1945. Specialization: Molecular Virology and Viral Immunology Address: Professor Emeritus, Department of Microbiology and Cell Biology, Indian Institute of Science, Bengaluru 560 012, Karnataka

  9. Ramdorai, Prof. Sujatha

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2004 Section: Mathematical Sciences. Ramdorai, Prof. Sujatha Ph.D. (Bombay), FNASc, FNA. Date of birth: 23 May 1962. Specialization: Algebra, Quadratic Forms, Number Theory and Iwasawa Theory Address: Professor, Department of Mathematics, University of British Columbia, ...

  10. Askey, Prof. Richard Allen

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1988 Honorary. Askey, Prof. Richard Allen. Date of birth: 4 June 1933. Address: 5915, American Parkway, Apt. 228, Madison, WI 43718, U.S.A.. Contact: Office: (+1-608) 262 2880. Residence: (+1-608) 233 7900. Fax: (+1-608) 263 8891. Email: askey@math.wisc.edu. YouTube; Twitter; Facebook ...

  11. Ramaswamy, Prof. Mythily

    Indian Academy of Sciences (India)

    Ramaswamy, Prof. Mythily Ph.D. (Paris), FNASc. Date of birth: 6 June 1954. Specialization: Nonlinear Functional Analysis, Partial Differential Equations, and Applications to Control Problems Address: Professor, TIFR Centre for Applicable Mathematics, P.B. No. 6503, Sharada Nagar, Bengaluru 560 065, Karnataka Contact:

  12. Adimurthi, Prof. Adi

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1996 Section: Mathematical Sciences. Adimurthi, Prof. Adi Ph.D. (Mumbai), FNA, FNASc. Date of birth: 19 March 1952. Specialization: Nonlinear Differential Equations Address: TIFR Centre for Applicable Mathematics, P.B. No. 6503, Sharada Nagar, Bengaluru 560 065, Karnataka

  13. Balasubramanian, Prof. Ramachandran

    Indian Academy of Sciences (India)

    Elected: 1987 Section: Mathematical Sciences. Balasubramanian, Prof. Ramachandran Ph.D. (Mumbai), FNA, FNASc. Council Service: 2007-2009. Date of birth: 15 March 1951. Specialization: Analytic Number Theory Address: Professor, The Institute of Mathematical Sciences, CIT Campus, Taramani, Chennai 600 113, ...

  14. Chaudhuri, Prof. Mihir Kanti

    Indian Academy of Sciences (India)

    Chaudhuri, Prof. Mihir Kanti Ph.D. (IIT, Kharagpur), Dr rer nat (FRG), FNA. Date of birth: 21 July 1947. Specialization: Synthesis, Structure & Reactivity, Newer Reagents and Methodologies and Green Chemical Technology Address: Adviser (Education), Government of Assam, Sachivalaya, Dispur, Guwahati 781 006, Assam

  15. Lahiri, Prof. Goutam Kumar

    Indian Academy of Sciences (India)

    Elected: 2005 Section: Chemistry. Lahiri, Prof. Goutam Kumar Ph.D. (Jadavpur). Date of birth: 1 January 1960. Specialization: Organometallic Chemistry and Catalysis Address: Professor, Department of Chemistry, Indian Institute of Technology, Powai, Mumbai 400 076, Maharashtra Contact: Office: (022) 2576 7159

  16. Chandrasekhar, Prof. Vadapalli

    Indian Academy of Sciences (India)

    Chandrasekhar, Prof. Vadapalli Ph.D. (IISc), FNA, FNASc, FTWAS Council Service: 2010-12. Date of birth: 6 November 1958. Specialization: Organometallic Chemistry, Inorganic Rings & Polymers and Many-Group Chemistry Address: Director, National Institute of Science Education & Research, Jatni P.O., Khordha 752 ...

  17. Chakrabarti, Prof. Bikas Kanta

    Indian Academy of Sciences (India)

    Chakrabarti, Prof. Bikas Kanta Ph.D. (Calcutta), FNA. Date of birth: 14 December 1952. Specialization: Statistical Physics, Condensed Matter Physics and Computational Physics & their Applications to Social Sciences Address: Senior Professor, Theoretical Condensed Matter Physics Divn., Saha Institute of Nuclear Physics, ...

  18. Balaji, Prof. Kithiganahalli Naranayaswamy

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2016 Section: General Biology. Balaji, Prof. Kithiganahalli Naranayaswamy Ph.D. (IISc), FNASc, FNA. Date of birth: 7 March 1966. Specialization: Immunology, Infectious Diseases Address: Department of Microbiology & Cell Biology, Indian Institute of Science, Bengaluru 560 012, Karnataka Contact:

  19. Sharma, Prof. Shobhona

    Indian Academy of Sciences (India)

    Sharma, Prof. Shobhona Ph.D. (Mumbai), FNA. Date of birth: 5 February 1953. Specialization: Molecular Parasitology, Parasite Immunology and Parasite Metabolism Address: Senior Professor & Chairperson, Department of Biological Sciences, Tata Institute of Fundamental Research, Homi Bhabha Road, Mumbai 400 005, ...

  20. Chakraborti, Prof. Asit Kumar

    Indian Academy of Sciences (India)

    Chakraborti, Prof. Asit Kumar Ph.D. (Jadavpur). Date of birth: 15 August 1954. Specialization: Synthetic Organic Chemistry, Green Chemistry, Medicinal Chemistry Address: Head, Department of Medicinal chemistry, National Institute of Pharmaceutical Education & Research, Sector 67, SAS Nagar 160 062, Panjab Contact:

  1. Patel, Prof. Bhisma Kumar

    Indian Academy of Sciences (India)

    Elected: 2018 Section: Chemistry. Patel, Prof. Bhisma Kumar Ph.D. (IIT, Kanpur), FNASc. Date of birth: 6 August 1965. Specialization: Organic Synthesis, Reaction Mechanisms, Green Chemistry Address: Department of Chemistry, Indian Institute of Technology, Guwahati 781 039, Assam Contact: Office: (0361) 258 2307

  2. Lewis, Prof. Gilbert Newton

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Lewis, Prof. Gilbert Newton. Date of birth: 25 October 1875. Date of death: 24 March 1946. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on ...

  3. Paulraj, Prof. Arogyaswami J

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2014 Honorary. Paulraj, Prof. Arogyaswami J. Date of birth: 1944. Address: Information Systems Laboratory, Stanford University, 232, David Packard EE Building, 350, Serra Mall, Stanford, CA 94305-9510, USA Contact: Email: apaulraj@stanford.edu. YouTube; Twitter; Facebook ...

  4. Zare, Prof. Richard N

    Indian Academy of Sciences (India)

    ... Refresher Courses · Symposia · Live Streaming. Home; Fellowship. Fellow Profile. Elected: 2009 Honorary. Zare, Prof. Richard N. Date of birth: 19 November 1939. Address: Department of Chemistry, Stanford University, Stanford, CA 94305-5080, USA Contact: Email: zare@stanford.edu. YouTube; Twitter; Facebook ...

  5. Imry, Prof. Yoseph

    Indian Academy of Sciences (India)

    Imry, Prof. Yoseph. Date of birth: 1939. Address: Dept of Condensed Matter Physics, The Weizmann Institute of Science, Rehovot 76100, Israel Contact: Office: (+972-8) 934 4064. Residence: (+972-8) 934 3506. Fax: (+972-8) 934 4477. Email: yoseph.imry@weizmann.ac.il. YouTube; Twitter; Facebook; Blog ...

  6. Muller, Prof. Paul Hermann

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1965 Honorary. Muller, Prof. Paul Hermann Nobel Laureate (Medicine) - 1948. Date of birth: 12 January 1899. Date of death: 13 October 1965. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  7. Sarin, Prof. Shiv Kumar

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2005 Section: Medicine. Sarin, Prof. Shiv Kumar D.M. (AIIMS), M.D. (Jaipur), FNA, FNASc, FAMS. Date of birth: 20 August 1952. Specialization: Hepatology Address: Director, Institute of Liver & Biliary Sciences, D1, Vasant Kunj, New Delhi 110 070, U.T.. Contact: Office: (011) 4630 ...

  8. Robinson, Prof. Robort

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Robinson, Prof. Robort Nobel Laureate (Chemistry) - 1947. Date of birth: 13 September 1886. Date of death: 8 February 1975. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  9. Pai, Prof. Mangalore Anantha

    Indian Academy of Sciences (India)

    Elected: 1979 Section: Engineering & Technology. Pai, Prof. Mangalore Anantha Ph.D. (UC, Berkeley), FNA, FNAE, FIEEE. Date of birth: 5 October 1931. Specialization: Smart Grid, Power Systems, Stability, Control and Computation Address: Emeritus Professor, Department of Electrical & Computer Engineering, University ...

  10. Ginzburg, Prof. Vitaly Lasazevich

    Indian Academy of Sciences (India)

    ... Refresher Courses · Symposia · Live Streaming. Home; Fellowship. Fellow Profile. Elected: 1977 Honorary. Ginzburg, Prof. Vitaly Lasazevich. Date of birth: 4 October 1916. Date of death: 8 November 2009. Last known address: Professor and Member of the Russian, Academy of Sciences, P N Lebedev Physical Institute, ...

  11. Bondi, Prof. Sir Hermann

    Indian Academy of Sciences (India)

    ... Public Lectures · Lecture Workshops · Refresher Courses · Symposia · Live Streaming. Home; Fellowship. Fellow Profile. Elected: 1997 Honorary. Bondi, Prof. Sir Hermann KCB, FRS. Date of birth: 1 November 1919. Date of death: 10 September 2005. Last known address: Fellow, Churchill College, Cambridge, CB3 0DS, ...

  12. Oda, Prof. Minoru

    Indian Academy of Sciences (India)

    Annual Meetings · Mid Year Meetings · Discussion Meetings · Public Lectures · Lecture Workshops · Refresher Courses · Symposia · Live Streaming. Home; Fellowship. Fellow Profile. Elected: 1995 Honorary. Oda, Prof. Minoru. Date of birth: 24 February 1923. Date of death: 1 March 2001. Last known address: Tokyo ...

  13. Parthasarathy, Prof. Rajagopalan

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  14. Rao, Prof. Maddali Nageswara

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  15. Pal, Prof. Arup Kumar

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  16. Mathur, Prof. Pradeep

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  17. Jain, Prof. Sanjay

    Indian Academy of Sciences (India)

    Jain, Prof. Sanjay Ph.D. (Bombay). Date of birth: 31 January 1960. Specialization: Mathematical Modelling of Complex Systems, Structure, Dynamics and Evolution of Biological & Social Networks, Theoretical Systems Biology Address: Professor, Department of Physics & Astrophysics, University of Delhi, Delhi 110 007, U.T.

  18. Saidapur, Prof. Srinivas Kishanrao

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1993 Section: Animal Sciences. Saidapur, Prof. Srinivas Kishanrao Ph.D. (Karnatak), FNA, FNASc, FTWAS. Date of birth: 7 March 1947. Specialization: Biology of Reproduction, Comparative Endocrinology, Herpetology and Animal Behaviour Address: Plot No. 108, Sripad Nagar, Saptapur, Dharwad ...

  19. Joshi, Prof. Amitabh

    Indian Academy of Sciences (India)

    Joshi, Prof. Amitabh Ph.D. (Washington State), FNASc, FNA. Date of birth: 4 March 1965. Specialization: Population & Quantitative Genetics, Evolutionary Genetics and Population Ecology Address: Professor, Evolutionary & Organismal Biology Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur P.O., ...

  20. Dharmalingam, Prof. Kuppamuthu

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1993 Section: General Biology. Dharmalingam, Prof. Kuppamuthu Ph.D. (MKU), FNASc. Date of birth: 3 January 1949. Specialization: Proteomics of Eye Diseases, Molecular Genetics, Genetic Engineering and Biotechnology Address: Director - Research, Aravind Medical Research Foundation, 1, ...

  1. Mishra, Prof. Manoj Kumar

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1999 Section: Chemistry. Mishra, Prof. Manoj Kumar Ph.D. (Florida), FNASc. Date of birth: 15 October 1952. Specialization: Electronic Structure Theory, Photo/Collisional Dynamics Address: Vice Chancellor, Birla Institute of Technology, Mesra, Ranchi 835 215, Jharkhand Contact:

  2. Balasubramanian, Prof. Sundaram

    Indian Academy of Sciences (India)

    Balasubramanian, Prof. Sundaram Ph.D. (IISc). Date of birth: 5 June 1966. Specialization: Ionic Liquids, Moulding Enzymes, Supramolecular Polymers, Molecular Simulations, Computational Chemistry Address: Chemistry & Physics of Materials Unit, JN Centre for Advanced Scientific Research, Jakkur, Bengaluru 560 064, ...

  3. Balasubramanian, Prof. Aiylam Subramania

    Indian Academy of Sciences (India)

    Balasubramanian, Prof. Aiylam Subramania Ph.D. (Kerala), FAMS. Date of birth: 15 July 1937. Specialization: Neurochemistry and Enzymology Address: 16/7A, First New Street, Thirunagar, Vellore 632 006, T.N.. Contact: Residence: (0416) 224 6260. Email: balabsu7@hotmail.com. YouTube · Twitter · Facebook · Blog ...

  4. Bhalla, Prof. Upinder Singh

    Indian Academy of Sciences (India)

    Bhalla, Prof. Upinder Singh Ph.D. (CIT), FNA. Date of birth: 21 June 1963. Specialization: Systems Biology, Computational Neuroscience and Systems Neurobiology Address: Associate Professor, National Centre for Biological Sciences, GKVK Campus, Bengaluru 560 065, Karnataka Contact: Office: (080) 2366 6130

  5. Pani, Prof. Amiya Kumar

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2012 Section: Mathematical Sciences. Pani, Prof. Amiya Kumar Ph.D. (IIT, Kanpur), FNASc. Date of birth: 3 June 1957. Specialization: Numerical Analysis, Partial Differential Equations, Industrial Mathematics Address: Chair Professor, Department of Mathematics, Indian Institute of Technology, Powai, ...

  6. Bose, Prof. Indrani

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2000 Section: Physics. Bose, Prof. Indrani Ph.D. (Calcutta), FNASc. Date of birth: 15 August 1951. Specialization: Theoretical Condensed Matter Physics, Statistical Physics, Biological Physics and Systems Biology Address: Emeritus Scientist, Department of Physics, Bose Institute, ...

  7. Balasubramanian, Prof. Kunissery Ananthasubramanian

    Indian Academy of Sciences (India)

    Elected: 2002 Section: Medicine. Balasubramanian, Prof. Kunissery Ananthasubramanian Ph.D. (Madras), FNASc, FAMS. Date of birth: 6 April 1945. Specialization: Oxidative Stress, Gastrointestinal Mucosa and Pathophysiology Address: No. 49, Guruthoppu Phase 1, II Street, Sathuvachari, Vellore 632 009, T.N.. Contact:

  8. Ramasubramanian, Prof. Sundareswaran

    Indian Academy of Sciences (India)

    Ramasubramanian, Prof. Sundareswaran Ph.D. (ISI). Date of birth: 3 March 1952. Specialization: Stochastic Processes, Stochastic Models in Insurance Address: Professor, Statistics & Mathematics Unit, Indian Statistical Institute, R.V. College P.O., Bengaluru 560 059, Karnataka Contact: Office: (080) 2848 3002-4&6/476

  9. Karman, Prof. Theodore von

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1961 Honorary. Karman, Prof. Theodore von. Date of birth: 11 May 1881. Date of death: 6 May 1963. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on the ...

  10. Cabannes, Prof. Jean

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1949 Honorary. Cabannes, Prof. Jean. Date of birth: 12 August 1885. Date of death: 31 October 1959. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on the ...

  11. Fischer, Prof. Hans

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Fischer, Prof. Hans Nobel Laureate (Chemistry) - 1930. Date of birth: 27 July 1881. Date of death: 31 March 1945. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science ...

  12. Granit, Prof. Ragnar Arthur

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1964 Honorary. Granit, Prof. Ragnar Arthur Nobel Laureate (Medicine) - 1967. Date of birth: 30 October 1900. Date of death: 11 March 1991. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  13. Cousteau, Prof. Jacques Yves

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1978 Honorary. Cousteau, Prof. Jacques Yves. Date of birth: 11 June 1910. Date of death: 25 June 1997. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on ...

  14. Millikan, Prof. Robert Andrews

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Millikan, Prof. Robert Andrews Nobel Laureate (Physics) - 1923. Date of birth: 22 March 1868. Date of death: 19 December 1953. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  15. Heisenberg, Prof. Werner Karl

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Heisenberg, Prof. Werner Karl Nobel Laureate (Physics) - 1932. Date of birth: 5 December 1901. Date of death: 1 February 1976. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  16. Niggli, Prof. Paul

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1937 Honorary. Niggli, Prof. Paul. Date of birth: 26 June 1888. Date of death: 13 January 1953. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on the teaching ...

  17. Hill, Prof. Archibald Vivian

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Hill, Prof. Archibald Vivian Nobel Laureate (Medicine) - 1922. Date of birth: 26 September 1886. Date of death: 3 June 1977. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  18. Hess, Prof. Walter Rudolf

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1966 Honorary. Hess, Prof. Walter Rudolf Nobel Laureate (Medicine) - 1949. Date of birth: 17 March 1881. Date of death: 12 August 1973. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three ...

  19. Herzberg, Prof. Gerhard

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1955 Honorary. Herzberg, Prof. Gerhard Nobel Laureate (Chemistry) - 1971. Date of birth: 25 December 1904. Date of death: 4 March 1999. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  20. Eccles, Prof. John Carew

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1968 Honorary. Eccles, Prof. John Carew Nobel Laureate (Medicine) - 1963. Date of birth: 27 January 1903. Date of death: 2 May 1997. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three ...

  1. Hadamard, Prof. Jacques

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1939 Honorary. Hadamard, Prof. Jacques. Date of birth: 8 December 1865. Date of death: 17 October 1963. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on ...

  2. Prasad, Prof. Surendra

    Indian Academy of Sciences (India)

    Prasad, Prof. Surendra Ph.D. (IIT, Delhi), FNA, FNAE, FNASc. Council Service: 2007-12. Date of birth: 10 July 1948. Specialization: Signal Processing, Communication Theory and Systems Address: Emeritus Professor, Department of Electrical Engineering, Indian Institute of Technology, Hauz Khas, New Delhi 110 016, U.T.

  3. Balaram, Prof. Padmanabhan

    Indian Academy of Sciences (India)

    Balaram, Prof. Padmanabhan Ph.D. (Carnegie Mellon), FNA, FNASc. Council Service: 1995-2000. Date of birth: 19 February 1949. Specialization: Bio-organic Chemistry and Molecular Biophysics Address: Molecular Biophysics Unit, Indian Institute of Science, Bengaluru 560 012, Karnataka Contact: Office: (080) 2293 3000

  4. Kesavan, Prof. Srinivasan

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2008 Section: Mathematical Sciences. Kesavan, Prof. Srinivasan Ph.D. (Pierre et Marie Curie), FNASc. Date of birth: 17 January 1952. Specialization: Partial Differential Equations, Homogenization and Isoperimetric Inequalities Address: 33/19, Barnaby Road, Kilpauk, Chennai 600 010, T.N.. Contact:

  5. Roy, Prof. Durga Prasad

    Indian Academy of Sciences (India)

    Roy, Prof. Durga Prasad Ph.D. (Mumbai), FNA, FNASc. Date of birth: 29 July 1941. Date of death: 17 March 2017. Specialization: Particle Physics, Astroparticle Physics Last known address: INSA Honorary Scientist, Homi Bhabha Centre for Science Education, V N Purav Marg, Mankhurd, Mumbai 400 088, Maharashtra.

  6. Ramachandran, Prof. Janakiraman

    Indian Academy of Sciences (India)

    Ramachandran, Prof. Janakiraman Ph.D. (UC, Berkeley). Date of birth: 12 June 1935. Specialization: Molecular Biology Address: Chairman, Gangagen Biotechnologies Private Limited, 12, 5th Cross, Raghavendra Layout, Tumkuar Road, Yeshwantpur, Bengaluru 560 022, Karnataka Contact: Office: (080) 4062 1300-328

  7. Datta, Prof. Asis

    Indian Academy of Sciences (India)

    Datta, Prof. Asis Ph.D and D.Sc. (Calcutta), FNA, FNASc, FTWAS. Date of birth: 2 February 1944. Specialization: Biochemistry, Molecular Biology and Genetic Engineering Address: Distinguished Scientist, National Institute of Plant Genome Research, Aruna Asaf Ali Marg, P.O. Box 10531, New Delhi 110 067, U.T.. Contact:

  8. Lorenz, Prof. Edward Norton

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1981 Honorary. Lorenz, Prof. Edward Norton. Date of birth: 23 May 1917. Date of death: 16 April 2008. Last known address: Department of Earth, Atmospheric &, Planetary Sciences, Massachusetts Institute of, Technology, Cambridge, MA 02139, U.S.A.. YouTube; Twitter; Facebook ...

  9. Liepmann, Prof. Hans Wolfgang

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1985 Honorary. Liepmann, Prof. Hans Wolfgang. Date of birth: 3 July 1914. Date of death: 24 June 2009. Last known address: Theodore von Karman Professor of, Aeronautics (Emeritus), Graduate Aeronautical Laboratories, California Institute of Technology, Pasadena, CA 91125, ...

  10. Parulkar, Prof. Gurukumar Bhalchandra

    Indian Academy of Sciences (India)

    Parulkar, Prof. Gurukumar Bhalchandra M.S. (Mumbai), FAMS. Date of birth: 1 December 1931. Specialization: Open Heart Surgery, Extracorporeal Circulation, Coronary Bypass Surgery and Vascular Surgery Address: Flat No. 31, Building 4, Haji Ali Government Colony, K K Marg, Mumbai 400 034, Maharashtra Contact:

  11. Mondal, Prof. Naba Kumar

    Indian Academy of Sciences (India)

    Mondal, Prof. Naba Kumar Ph.D. (Bombay) D.Sc. (h.c.), FNA, FNASc, FTWAS. Date of birth: 11 March 1951. Specialization: Experimental Particle Physics, Accelerator-based Particle Physics and Neutrino Physics Address: Raja Ramanna Fellow, Saha Institute of Nuclear Physics, 1/AF, Bidhan Nagar, Kolkata 700 064, W.B.

  12. Chakraborty, Prof. Ranajit

    Indian Academy of Sciences (India)

    Elected: 2006 Honorary. Chakraborty, Prof. Ranajit. Date of birth: 1946. Address: Director, Center for Computational Genomics, University of North Texas, HSC, 3500 Camp Bowie Blvd, CBH 249, Fort Worth, TX 76107, U.S.A.. Contact: Office: (+1-817) 735 2421. Fax: (+1-817) 735 5016. Email: ranajit.chakraborty@unthsc.

  13. Bahadur, Prof. Raghu Raj

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1975 Section: Mathematical Sciences. Bahadur, Prof. Raghu Raj Ph.D. (North Carolina), FNA. Date of birth: 30 April 1924. Date of death: 7 June 1997. Specialization: Mathematical Statistics Address: No.9, Raj Narain Road, Apartment 4A, Civil Lines, Delhi 110 054. YouTube; Twitter; Facebook; Blog ...

  14. Kahn, Prof. Oliver

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1999 Honorary. Kahn, Prof. Oliver. Date of birth: 13 September 1942. Date of death: 8 December 1999. Last known address: Laboratoire des Sciences Moléculair, Institut de Chimie de la Matire, Condensée de Bordeaux, UPR CNRS No. 9048, 33608 Pessac, France. YouTube; Twitter; Facebook ...

  15. Rao, Prof. Valipe Ramgopal

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2009 Section: Engineering & Technology. Rao, Prof. Valipe Ramgopal FNAE, FNASc, FNA, FIEEE. Date of birth: 16 August 1965. Specialization: Nanoelectronics and Nanotechnology Address: Director, Indian Institute of Technology, Hauz Khas, New Delhi 110 016, U.T.. Contact:

  16. Houssay, Prof. Bernardo Alberto

    Indian Academy of Sciences (India)

    SPEAKER: Prof. Krishnaswamy Ravi-Chandar. VENUE: Faculty Hall, Indian Institute of Science. 23 February 2018 ǀ 1500. Event poster · Introducing: Summer Schools. Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and ...

  17. Born, Prof. Max

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1937 Honorary. Born, Prof. Max Nobel Laureate (Physics) - 1954. Date of birth: 11 December 1882. Date of death: 5 January 1970. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science ...

  18. Compton, Prof. Arthur Holly

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Compton, Prof. Arthur Holly Nobel Laureate (Physics) - 1927. Date of birth: 10 September 1892. Date of death: 15 March 1962. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  19. Salam, Prof. Abdus

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1988 Honorary. Salam, Prof. Abdus Nobel Laureate (Physics) - 1979. Date of birth: 29 January 1926. Date of death: 21 November 1996. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three ...

  20. Leiper, Prof. Robert Thomson

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1938 Honorary. Leiper, Prof. Robert Thomson. Date of birth: 17 April 1881. Date of death: 21 May 1969. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on the ...

  1. Bowen, Prof. Norman Levi

    Indian Academy of Sciences (India)

    SPEAKER: Prof. Krishnaswamy Ravi-Chandar. VENUE: Faculty Hall, Indian Institute of Science. 23 February 2018 ǀ 1500. Event poster · Introducing: Summer Schools. Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and ...

  2. Anderson, Prof. John Stuart

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1978 Honorary. Anderson, Prof. John Stuart. Date of birth: 9 January 1908. Date of death: 25 December 1990. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India ...

  3. Ruzicka, Prof. Leopold Stephen

    Indian Academy of Sciences (India)

    SPEAKER: Prof. Krishnaswamy Ravi-Chandar. VENUE: Faculty Hall, Indian Institute of Science. 23 February 2018 ǀ 1500. Event poster · Introducing: Summer Schools. Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and ...

  4. Halle, Prof. Thore Gustaf.

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1947 Honorary. Halle, Prof. Thore Gustaf. Date of birth: 25 September 1884. Date of death: 12 May 1964. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on ...

  5. Engstrom, Prof. Arne Vilhelm

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1970 Honorary. Engstrom, Prof. Arne Vilhelm. Date of birth: 15 May 1920. Date of death: 19 July 1996. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on the ...

  6. Hodgkin, Prof. Dorothy Crowfoot

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1972 Honorary. Hodgkin, Prof. Dorothy Crowfoot Nobel Laureate (Chemistry) - 1964. Date of birth: 12 May 1910. Date of death: 29 July 1994. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  7. Mulliken, Prof. Robert Sanderson

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1969 Honorary. Mulliken, Prof. Robert Sanderson Nobel Laureate (Chemistry) - 1966. Date of birth: 7 June 1896. Date of death: 31 October 1986. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  8. Charney, Prof. Jule Gregory

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1980 Honorary. Charney, Prof. Jule Gregory. Date of birth: 1 January 1917. Date of death: 16 June 1981. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on ...

  9. Hahn, Prof. Otto

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1958 Honorary. Hahn, Prof. Otto Nobel Laureate (Chemistry) - 1944. Date of birth: 8 March 1879. Date of death: 28 July 1968. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science ...

  10. Medawar, Prof. Peter Brian

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1968 Honorary. Medawar, Prof. Peter Brian Nobel Laureate (Medicine) - 1960. Date of birth: 28 February 1915. Date of death: 2 October 1987. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  11. Seward, Prof. Albert Charles

    Indian Academy of Sciences (India)

    SPEAKER: Prof. Krishnaswamy Ravi-Chandar. VENUE: Faculty Hall, Indian Institute of Science. 23 February 2018 ǀ 1500. Event poster · Introducing: Summer Schools. Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and ...

  12. Cotton, Prof. Aime Auguste

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Cotton, Prof. Aime Auguste. Date of birth: 9 October 1869. Date of death: 16 April 1951. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on the ...

  13. Minwalla, Prof. Shiraz

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2011 Section: Physics. Minwalla, Prof. Shiraz Ph.D. (Princeton). Date of birth: 2 January 1972. Specialization: String Theory, Gravity, Quantum Field Theory Address: Department of Theoretical Physics, Tata Institute of Fundamental Research, Homi Bhabha Road, Mumbai 400 005, ...

  14. Pandian, Prof. Thavamani Jegajothivel

    Indian Academy of Sciences (India)

    Elected: 1985 Section: Animal Sciences. Pandian, Prof. Thavamani Jegajothivel Ph.D. (Madras), Dr. rer. nat. (Kiel, Germany), FNA, FNASc, FNAAS, FTWAS, D.Sc. (CIFE, Mumbai). Date of birth: 15 June 1939. Specialization: Genetics and Energetics: Aquaculture Address: 9, Old Natham Road, Opp. Balamandiram, Madurai ...

  15. Rao, Prof. Basuthkar Jagadeeshwar

    Indian Academy of Sciences (India)

    Rao, Prof. Basuthkar Jagadeeshwar Ph.D. (IISc), FNASc, FNA. Date of birth: 13 March 1956. Specialization: Genome Dynamics, Biology of Cellular Adaptations, Computational Biology Address: Department of Biological Sciences, Tata Institute of Fundamental Research, Homi Bhabha Road, Mumbai 400 005, Maharashtra

  16. Haritsa, Prof. Jayant Ramaswamy

    Indian Academy of Sciences (India)

    Elected: 2011 Section: Engineering & Technology. Haritsa, Prof. Jayant Ramaswamy Ph.D. (Wisconsin), FNAE, FNASc, FIEEE. Date of birth: 10 March 1964. Specialization: Database Systems Address: FACM Professor, Dept. of Computational & Data Sciences, Indian Institute of Science, Bengaluru 560 012, Karnataka

  17. Chandru, Prof. Vijay

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1996 Section: Engineering & Technology. Chandru, Prof. Vijay Ph.D. (MIT). Date of birth: 7 June 1953. Specialization: Data Science, Computational Mathematics and Computational Biology Address: Chairman, Strand Life Sciences, 591, III Main Road, Sadashivanagar, Bengaluru 560 080, Karnataka

  18. Caspersson, Prof. Torbjorn Oskar

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1963 Honorary. Caspersson, Prof. Torbjorn Oskar. Date of birth: 15 October 1910. Date of death: 7 December 1997. Last known address: Professor, Department of Tumor Pathology, Karolinska Sjukhuset, S-104 01 Stockholm 60, Sweden. YouTube; Twitter; Facebook; Blog ...

  19. Gandhi, Prof. Kandukuri Sivananda

    Indian Academy of Sciences (India)

    Elected: 1990 Section: Engineering & Technology. Gandhi, Prof. Kandukuri Sivananda Ph.D. (UC, Berkeley). Date of birth: 23 December 1942. Specialization: Batteries and Fuel Cells, Multiphase Fluid Systems and Polymer Reaction Engineering Address: Department of Chemical Engineering, Indian Institute of Science, ...

  20. Rao, Prof. Palle Rama

    Indian Academy of Sciences (India)

    Rao, Prof. Palle Rama Ph.D. (Banaras), F.Eng. (UK), FNA, FNASc, FNAE, FASM, FTWAS, Foreign Member - US Natl. Acad. Engg. Council Service: 1989-2000; Vice-President: 1992-94; President: 1995-97. Date of birth: 30 June 1937. Specialization: Deformation, Fracture and Materials Development Address: Chairman ...

  1. Rao, Prof. Aroor Pramesh

    Indian Academy of Sciences (India)

    Rao, Prof. Aroor Pramesh Ph.D. (Mumbai). Date of birth: 18 January 1948. Specialization: Sun & Solar Wind, Wave Propagation in Random Media, Aperture Synthesis and Radio Imaging Address: Flat 7, Khagol Housing Society, Panchavati, Pashan, Pune 411 008, Maharashtra Contact: Residence: (020) 6628 0183

  2. Rao, Prof. Kalya Jagannatha

    Indian Academy of Sciences (India)

    Rao, Prof. Kalya Jagannatha Ph.D. (IIT, Kanpur), D.Sc. (IISc), FNA, FNASc, D.Sc. (h.c., Univ. Bordeaux, France) Council Service: 1998-2003. Date of birth: 7 December 1940. Specialization: Amorphous Solids & Ceramics and Phase Transitions Address: 187/1, Tadvanam Estate, Halasinganahalli Road, Kalya Post, Magadi ...

  3. Rao, Prof. Arikkala Raghurama

    Indian Academy of Sciences (India)

    Elected: 2012 Section: Physics. Rao, Prof. Arikkala Raghurama Ph.D. (Mumbai). Date of birth: 14 June 1954. Specialization: X-ray Astronomy, X-ray Instrumentation, High Energy Astrophysics Address: Department of Astronomy & Astrophysics, Tata Institute of Fundamental Research, Homi Bhabha Road, Mumbai 400 005, ...

  4. Rao, Prof. Calyampudi Radhakrishna

    Indian Academy of Sciences (India)

    Date of birth: 10 September 1920. Specialization: Statistics with Applications to Biology, Signal Processing and Pattern Recognition Address: Distinguished Professor Emeritus, CR Rao Advanced Institute, University of Hyderabad Campus, Prof. CR Rao Road, Hyderabad 500 046, A.P.. Contact: Office: (040) 2313 1170

  5. Rao, Prof. Chebrolu Pulla

    Indian Academy of Sciences (India)

    Rao, Prof. Chebrolu Pulla Ph.D. (IISc), FNASc, FNA. Date of birth: 13 May 1954. Specialization: Bioinorganic Chemistry, Supramolecular Chemistry, Ion & Molecular Receptors, Metalloproteins & Metalloenzymes Address: Institute Chair Professor, Department of Chemistry, Indian Institute of Technology, Powai, Mumbai 400 ...

  6. Bhattacharjee, Prof. Jayanta Kumar

    Indian Academy of Sciences (India)

    Bhattacharjee, Prof. Jayanta Kumar Ph.D. (Maryland), FNASc. Date of birth: 10 April 1952. Specialization: Critical Phenomena, Turbulence and Nonlinear Dynamics Address: Distinguished Emeritus Fellow, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700 032, W.B.. Contact: Residence: 98307 47103

  7. Tandon, Prof. Prakash Narain

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1983 Section: Medicine. Tandon, Prof. Prakash Narain M.B.B.S. (Lucknow), M.S., D.Sc. (h.c.), FRCS, FNA, FNASc, FTWAS, FAMS. Date of birth: 13 August 1928. Specialization: Neurosciences and Neurosurgery Address: No. 1, Jagriti Enclave, Vikas Marg Extension, Delhi 110 092, ...

  8. Bera, Prof. Jitendra Kumar

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2014 Section: Chemistry. Bera, Prof. Jitendra Kumar Ph.D. (IISc). Date of birth: 24 October 1968. Specialization: Organometallic Chemistry, Small Molecule Activation, Catalysis Address: Department of Chemistry, Indian Institute of Technology, Kanpur 208 016, U.P.. Contact: Office: ...

  9. Schmidt, Prof. Brian P

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2014 Honorary. Schmidt, Prof. Brian P Nobel Laureate (Physics), FRS. Date of birth: 24 February 1967. Address: Vice Chancellor, The Australian National University, via Cotter Road, Weston Creek, ACT 2611, Australia Contact: Office: (+61-2) 6125 2510. Fax: (+61-2) 6125 0260

  10. Yadav, Prof. Veejendra Kumar

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2007 Section: Chemistry. Yadav, Prof. Veejendra Kumar Ph.D. (Baroda). Date of birth: 13 June 1956. Specialization: Synthetic Organic Chemistry and Physical Organic Chemistry Address: Professor, Department of Chemistry, Indian Institute of Technology, Kanpur 208 016, U.P.

  11. Sarkar, Prof. Debi Prasad

    Indian Academy of Sciences (India)

    Sarkar, Prof. Debi Prasad Ph.D. (Calcutta), FNASc, FNA. Date of birth: 15 January 1958. Specialization: Membrane Biology, Biochemistry, Molecular Virology, Cell Biology and Biotechnology Address: Director, Indian Institute of Science Education & Research, Sector 81, Manuli, SAS Nagar 140 306, Chandigarh Contact:

  12. Rao, Prof. Kaza Kesava

    Indian Academy of Sciences (India)

    Elected: 1992 Section: Engineering & Technology. Rao, Prof. Kaza Kesava Ph.D. (Houston). Date of birth: 12 April 1956. Specialization: Flow of Granular Materials and Defluoridation of Drinking Water Address: Professor, Department of Chemical Engineering, Indian Institute of Science, Bengaluru 560 012, Karnataka

  13. Semenov, Prof. Nikolai Nikolaevich

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1960 Honorary. Semenov, Prof. Nikolai Nikolaevich Nobel Laureate (Chemistry) - 1956. Date of birth: 16 April 1896. Date of death: 26 September 1986. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement ...

  14. Garrett, Prof. Stephen Denis

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1973 Honorary. Garrett, Prof. Stephen Denis. Date of birth: 1 November 1906. Date of death: 26 December 1989. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of ...

  15. Cheetham, Prof. Antony Kevin

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2001 Honorary. Cheetham, Prof. Antony Kevin FRS. Date of birth: 16 November 1946. Address: Dept. of Materials Science &, Metallurgy, University of Cambridge, 27, Charles Babbage Road, Cambridge CB3 0FS, uk. Contact: Office: (+44-1223) 74 6733. Fax: (+44-1223) 33 4567

  16. Dighe, Prof. Rajan Ramakant

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2010 Section: Animal Sciences. Dighe, Prof. Rajan Ramakant Ph.D. (IISc), FNASc, FNA. Date of birth: 21 March 1951. Specialization: Molecular Endocrinology, Reproductive Biology, Biochemistry Address: Molecular Reproduction & Developmental Genetics, Indian Institute of Science, Bengaluru 560 ...

  17. Kant, Prof. Tarun

    Indian Academy of Sciences (India)

    Kant, Prof. Tarun Ph.D. (IIT, Bombay), FNA, FNAE, FNASc. Date of birth: 1 July 1946. Specialization: Solid & Structural Mechanics, Finite Element Methods and Mechanics of Composite Materials & Structures Address: Professor Emeritus &INSA Senior Scientist, Department of Civil Engineering, Indian Institute of Technology, ...

  18. Kant, Prof. Rama

    Indian Academy of Sciences (India)

    Elected: 2015 Section: Chemistry. Kant, Prof. Rama Ph.D. (IISc). Date of birth: 18 January 1963. Specialization: Complex Systems in Electrochemistry & Polymers, Theoretical Chemistry, Nanoelectrochemistry Address: Department of Chemistry, University of Delhi, Delhi 110 007, U.T.. Contact: Office: (011) 2766 6646/188

  19. Das, Prof. Prasanta Kumar

    Indian Academy of Sciences (India)

    Elected: 2017 Section: Chemistry. Das, Prof. Prasanta Kumar Ph.D. (Osmania). Date of birth: 2 June 1971. Specialization: Bio-organic Chemistry, Supramolecular Self Assemblies, Enzymology, Soft Nanocomposite in Cellular Transportation Address: Department of Biological Chemistry, Indian Association for the Cultivation ...

  20. Khorana, Prof. Har Gobind

    Indian Academy of Sciences (India)

    Elected: 1976 Honorary. Khorana, Prof. Har Gobind Nobel Laureate (Medicine) - 1968. Date of birth: 9 January 1922. Date of death: 9 November 2011. Last known address: Alfred P. Sloan Professor of, Biology and Chemistry, Massachusetts Institute of, Technology, 77 Massachusetts Ave., Cambridge, MA 02139, U.S.A..

  1. Kamal, Prof. Aditya Kumar

    Indian Academy of Sciences (India)

    Elected: 1974 Section: Engineering & Technology. Kamal, Prof. Aditya Kumar Dr. lng. (Paris). Date of birth: 5 July 1927. Specialization: Air Traffic Control, Surveillance, Automation, UAV, GPS, Cyber Security Address: 18, Crystal Circle, Burlington, MA 01803, USA Contact: Office: (+1-781) 890 3330/235. Residence: (+1-781) ...

  2. Dhavale, Prof. Dilip Dattatray

    Indian Academy of Sciences (India)

    Elected: 2009 Section: Chemistry. Dhavale, Prof. Dilip Dattatray Ph.D. (Pune), FNASc. Date of birth: 18 February 1956. Specialization: Natural Products Chemistry, Carbohydrate Chemistry, Photochemistry, Reaction Mechanism, Medicinal Chemistry Address: Department of Chemistry, University of Pune, Pune 411 007, ...

  3. Kaliappan, Prof. Krishna Pillai

    Indian Academy of Sciences (India)

    Elected: 2016 Section: Chemistry. Kaliappan, Prof. Krishna Pillai Ph.D. (IISc). Date of birth: 16 March 1968. Specialization: Organic Synthesis, Medicinal Chemistry, Natural Products Address: Department of Chemistry, Indian Institute of Technology, Powai, Mumbai 400 076, Maharashtra Contact: Office: (022) 2576 7177

  4. Dasgupta, Prof. Pallab

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2015 Section: Engineering & Technology. Dasgupta, Prof. Pallab Ph.D. (IIT, Kharagpur), FNAE. Date of birth: 31 October 1967. Specialization: Electronic Design Automation, Artificial Intelligence, Formal Methods Address: Department of Computer Science & Engineering, Indian Institute of Technology ...

  5. Chakrabarti, Prof. Partha Pratim

    Indian Academy of Sciences (India)

    Elected: 2000 Section: Engineering & Technology. Chakrabarti, Prof. Partha Pratim Ph.D. (IIT, Kharagpur), FNA, FNAE. Date of birth: 1 October 1962. Specialization: Artificial Intelligence, Computer Aided Design for VLSI and Algorithms Address: Director, Indian Institute of Technology, Kharagpur 721 302, W.B.. Contact:

  6. Chhuttani, Prof. Pran Nath

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1975 Section: Medicine. Chhuttani, Prof. Pran Nath M.D., D.Sc. (h.c.). Date of birth: 26 February 1915. Date of death: 19 July 1996. Specialization: Gastroenterology and Internal Medicine Address: House No. 22, Sector 4, Chandigarh 160 001. YouTube · Twitter · Facebook · Blog ...

  7. Ramamritham, Prof. Krithivasan

    Indian Academy of Sciences (India)

    Elected: 2010 Section: Engineering & Technology. Ramamritham, Prof. Krithivasan Ph.D. (Utah), FNAE, FIEEE, FNASc. Date of birth: 28 February 1955. Specialization: Databases, Real-Time Systems, Use of Information & Communication Technology for Socioeconomic Development Address: Department of Computer ...

  8. Pitke, Prof. Madhukar Vishwanath

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1986 Section: Engineering & Technology. Pitke, Prof. Madhukar Vishwanath Ph.D. (Mumbai), FIEEE. Date of birth: 31 March 1936. Specialization: Electronics, Telecommunication & Information Technology, Technology Transfer and Wireless Communication Address: 002, Buniyad, Yashodham A2-15 ...

  9. Paul, Prof. Vinod Kumar

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2016 Section: Medicine. Paul, Prof. Vinod Kumar Ph.D. (AIIMS), FAMS, FNASc. Date of birth: 1 August 1955. Specialization: Paediatrics, Newborn Health Address: Department of Paediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, U.T.. Contact:

  10. Vijayraghavan, Prof. Usha

    Indian Academy of Sciences (India)

    Vijayraghavan, Prof. Usha Ph.D. (Caltech), FNA. Date of birth: 25 August 1961. Specialization: Plant Developmental Genetics, Microbial Genetics and Gene Regulation Address: Professor, Microbiology & Cell Biology Department, Indian Institute of Science, Bengaluru 560 012, Karnataka Contact: Office: (080) 2360 0168

  11. Mittal, Prof. Sanjay

    Indian Academy of Sciences (India)

    Mittal, Prof. Sanjay Ph.D. (Minnesota), FNAE, FNA, FNASc. Date of birth: 27 February 1968. Specialization: Unsteady Aerodynamics, Finite Element Analysis, High Performance Computing and Bluff-body Flows, Aerodynamic Shape Optimization Address: Department of Aerospace Engineering, Indian Institute of Technology, ...

  12. Padmanaban, Prof. Govindarajan

    Indian Academy of Sciences (India)

    Padmanaban, Prof. Govindarajan Ph.D. (IISc), FNA, FNASc, FTWAS Council Service: 1986-88, 1992-97; Vice-President: 1992-97. Date of birth: 20 March 1938. Specialization: Molecular Biology, Recombinant DNA and Malarial Parasite Address: NASI Senior Scientist, Department of Biochemistry, Indian Institute of Science, ...

  13. Gopalan, Prof. Kunchithapadam

    Indian Academy of Sciences (India)

    Elected: 1983 Section: Earth & Planetary Sciences. Gopalan, Prof. Kunchithapadam Ph.D. (IISc), FNA, FNASc. Date of birth: 12 August 1938. Specialization: Geo-& Cosmo-Chronology, Isotope Geology and Mass Spectrometry Address: 38765, Adcock Drive, Fremont, CA 94536, USA Contact: Residence: (+1-510) 386 4484

  14. Chaturvedi, Prof. Umesh Chandra

    Indian Academy of Sciences (India)

    Chaturvedi, Prof. Umesh Chandra M.D. (Lucknow), FRC Path. (London), FAMS, FNA, FNASc, FAAM(USA). Date of birth: 2 March 1939. Specialization: Medical Microbiology, Virology and Immunology Address: 201, Annapurna Apartments, No. 1, Bishop Rocky Street, Faizabad Road, Lucknow 226 007, U.P.. Contact:

  15. Rao, Prof. Addicam Jagannadha

    Indian Academy of Sciences (India)

    Rao, Prof. Addicam Jagannadha Ph.D. (IISc), FNA, FNASc, FAMS. Date of birth: 11 July 1942. Specialization: Regulation of Placental Function, Cellular Differentiation, Primate Biology, Oocyte Maturation Address: INSA Senior Scientist, Department of Biochemistry, Indian Institute of Science, Bengaluru 560 012, Karnataka

  16. Madhusudana, Prof. Nelamangala Vedavyasachar

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1974 Section: Physics. Madhusudana, Prof. Nelamangala Vedavyasachar Ph.D. (Mysore), FNA. Date of birth: 9 May 1944. Specialization: Liquid Crystals Address: INSA Senior Scientist, Liquid Crystal Laboratory, Raman Research Institute, CV Raman Avenue, Bengaluru 560 080, Karnataka Contact:

  17. Bhattacharya, Prof. Samaresh

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2006 Section: Chemistry. Bhattacharya, Prof. Samaresh Ph.D. (Jadavpur). Date of birth: 24 August 1960. Specialization: Co-ordination Chemistry and Organometallic Chemistry Address: Professor, Inorganic Chemistry Section, Department of Chemistry, Jadavpur University, Kolkata 700 032, W.B.

  18. Sengupta, Prof. Pulak

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2011 Section: Earth & Planetary Sciences. Sengupta, Prof. Pulak Ph.D. (Jadavpur), FNA. Date of birth: 5 December 1963. Specialization: Precambrian Geology, Metamorphic Petrology Address: Department of Geological Sciences, Jadavpur University, Kolkata 700 032, W.B.

  19. Indrayan, Prof. Abhaya

    Indian Academy of Sciences (India)

    Elected: 2010 Section: Medicine. Indrayan, Prof. Abhaya Ph.D. (Ohio State), FAMS. Date of birth: 11 November 1945. Specialization: Medical Biostatistics, Medical Research Methodology, Medical Informatics Address: A 037, Telecom City, B 9/6, Sector 62, Noida 201 309, U.P.. Contact: Residence: (0120) 240 0396

  20. Yegnanarayana, Prof. Bayya

    Indian Academy of Sciences (India)

    Elected: 2004 Section: Engineering & Technology. Yegnanarayana, Prof. Bayya Ph.D. (IISc), FNA, FNAE, FIEEE. Date of birth: 9 January 1944. Specialization: Signal Processing, Speech & Vision and Artificial Neural Networks Address: Professor, International Institute of Information Technology, Gachi Bowli, Hyderabad 500 ...

  1. Shenoy, Prof. Vijay Balakrishna

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  2. Bhattacharya, Prof. Sourendra Kumar

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1994 Section: Earth & Planetary Sciences. Bhattacharya, Prof. Sourendra Kumar Ph.D. (Gujarat), FNASc. Date of birth: 4 January 1948. Specialization: Isotope Geochemistry and Anomalous Isotope Fractionation Address: 406, Shri Raj Apartments, Vastrapur, Ahmedabad 380 015, Gujarat Contact:

  3. Nocera, Prof. Daniel G

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2013 Honorary. Nocera, Prof. Daniel G. Date of birth: 1957. Address: Dept. of Chemistry & Chem. Biol., Harvard University, 12, Oxford Street, Cambridge, MA 02138, USA Contact: Office: (+1-617) 495 8904. Email: dnocera@fas.harvard.edu. http://chemistry.harvard.edu/people/daniel-g-nocera.

  4. Livage, Prof. Jacques

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2004 Honorary. Livage, Prof. Jacques. Date of birth: 26 October 1938. Address: Chemie de la Matiere Condensee, UPMC, Tour 44, 4, Place Jussieu, 75005 Paris, France Contact: Office: (+33-1) 4427 6162. Residence: (+33-6) 6797 6839. Fax: (+33-1) 4427 4769

  5. Ashtekar, Prof. Abhay

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1996 Honorary. Ashtekar, Prof. Abhay. Date of birth: 5 July 1949. Address: Director, Inst. for Gravitation and, the Cosmos, Pennsylvania State University, University Park, PA 16802-6300, U.S.A.. Contact: Office: (+1-814) 863 9605. Residence: (+1-814) 867 8406. Fax: (+1-814) 863 ...

  6. Fisher, Prof. Michael Ellis

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2001 Honorary. Fisher, Prof. Michael Ellis FRS. Date of birth: 3 September 1931. Address: Distinguished Professor Emeritus, Institute of Physical Science and, Technology, University of Maryland, College Park, MD 20742-2431, U.S.A.. Contact: Office: (+1-301) 405 4819

  7. Roesky, Prof. Herbert Walter

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1997 Honorary. Roesky, Prof. Herbert Walter. Date of birth: 6 November 1935. Address: Director, Institut füer Anorganische Chemie, der Universität Göettingen, Tammannstrasse 4, D-37077 Göttingen, Germany Contact: Office: (+49-551) 393 0001. Residence: (+49-551) 76 183

  8. Anil Kumar, Prof.

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1987 Section: Chemistry. Anil Kumar, Prof. Ph.D. (IIT Kanpur), FNA, FNASc, FTWAS. Date of birth: 25 June 1941. Specialization: Nuclear Magnetic Resonance Spectroscopy, NMR ... Office: (080) 2293 2724. Residence: (080) 2366 2757. Mobile: 98454 21938. Fax: (080) 2360 1550

  9. Bhattacharyya, Prof. Archana

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2007 Section: Earth & Planetary Sciences. Bhattacharyya, Prof. Archana Ph.D. (Northwestern), FNASc, FNA. Date of birth: 1 June 1948. Specialization: Ionospheric Physics ... Office: (022) 2748 4147. Residence: (022) 2772 2014. Mobile: 96195 43004. Fax: (022) 2748 0762

  10. Das, Prof. Amita

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2011 Section: Physics. Das, Prof. Amita Ph.D. (IIT, Kanpur). Date of birth: 3 August 1965. Specialization: Strongly Coupled & Dusty Plasma Systems, Laser Plasma Interactions, Plasma Physics, Turbulence, Electron Magnetohydrodynamics Address: ... Office: (079) 2396 2078

  11. Griffiths, Prof. Phillip

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2004 Honorary. Griffiths, Prof. Phillip. Date of birth: 19 October 1938. Address: Director Emeritus Professor of, Mathematics, Institute for Advanced Study, No. 1, Einstein Drive, Princeton, NJ 08540, U.S.A.. Contact: Office: (+1-609)734 8041. Residence: (+1-410) 810 3103

  12. Anand, Prof. Gargeshwari Venkatasubbiah

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1997 Section: Engineering & Technology. Anand, Prof. Gargeshwari Venkatasubbiah Ph.D. (IISc), FNAE. Date of birth: 16 October 1943. Specialization: Statistical Signal ... III Stage, Bengaluru 560 085, Karnataka Contact: Office: (080) 2672 1983/838. Residence: (080) 2361 1263

  13. Veluthambi, Prof. Karuppanna

    Indian Academy of Sciences (India)

    Veluthambi, Prof. Karuppanna Ph.D. (IISc), FNA, FNASc. Date of birth: 7 March 1953. Specialization: Plant Genetic Engineering, Plant Biotechnology and Plant Molecular Biology Address: INSA Senior Scientist, Department of Plant Biotechnology, School of Biotechnology, Madurai Kamaraj University, Madurai 625 021, T.N.

  14. Tyagi, Prof. Jaya Sivaswami

    Indian Academy of Sciences (India)

    Elected: 2008 Section: Medicine. Tyagi, Prof. Jaya Sivaswami Ph.D. (Delhi), FNASc, FNA. Date of birth: 19 May 1954. Specialization: Molecular Biology, Mycobacteriology and Gene Regulation Address: Head, Department of Biotechnology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, U.T.

  15. Raman, Prof. Rajiva

    Indian Academy of Sciences (India)

    Elected: 1996 Section: Animal Sciences. Raman, Prof. Rajiva Ph.D. (Banaras), FNA, FNASc. Date of birth: 9 December 1948. Specialization: Human Molecular Genetics & Cytogenetics, Gene Expression & Chromatin Organization in Development and Sex Determination Address: Professor Emeritus, Department of Zoology, ...

  16. Lakshmanan, Prof. Muthusamy

    Indian Academy of Sciences (India)

    Elected: 1991 Section: Physics. Lakshmanan, Prof. Muthusamy Ph.D. (Madras), FNA, FNASc, FTWAS Council Service: 2010-12. Date of birth: 25 March 1946. Specialization: Nonlinear Dynamics, Theoretical Physics and Mathematical Physics Address: DST SERB Distinguished Fellow, Centre for Nonlinear Dynamics and, ...

  17. Mehta, Prof. Chandra Lal

    Indian Academy of Sciences (India)

    Elected: 1982 Section: Physics. Mehta, Prof. Chandra Lal Ph.D. (Rochester). Date of birth: 31 July 1938. Specialization: Quantum & Statistical Optics and Mathematical Physics Address: B-43, Gyandeep Apartments, Mayur Vihar, Phase I, New Delhi 110 091, U.T.. Contact: Residence: (011) 2279 6410. Mobile: 90133 91375

  18. Das, Prof. Saumitra

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2009 Section: General Biology. Das, Prof. Saumitra Ph.D. (Calcutta), FNASc, FNA. Date of birth: 20 January 1962. Specialization: Molecular Virology, Molecular Biology and Cell Biology Address: Microbiology and Cell Biology Department, Indian Institute of Science, Bengaluru 560 012, Karnataka

  19. Vijay Kumar, Prof. Panganamala

    Indian Academy of Sciences (India)

    Elected: 2017 Section: Engineering & Technology. Vijay Kumar, Prof. Panganamala Ph.D. (Southern Calif.), FNAE, FNA, FIEEE. Date of birth: 22 September 1955. Specialization: Codes for Distributed Storage, Error Correcting Codes, Wireless Communication Address: Department of Electrical Communication Engineering, ...

  20. Meyer, Prof. Kurt H.

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1952 Honorary. Meyer, Prof. Kurt H. Date of birth: 29 September 1883. Date of death: 14 April 1952. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on the ...

  1. Bhattacherjee, Prof. Satyendra Kumar

    Indian Academy of Sciences (India)

    Bhattacherjee, Prof. Satyendra Kumar Ph.D. (Notre Dame). Date of birth: 2 October 1926. Date of death: 28 April 2013. Specialization: Experimental Nuclear Physics Last known address: 302B, Tribute, Rajkamal Studio Compound, Off Dr SS Rao Road, Behind Mahatma Gandhi Memorial Hospital, Parel, Mumbai 400 012.

  2. Ahluwalia, Prof. Jagdish Chander

    Indian Academy of Sciences (India)

    Ahluwalia, Prof. Jagdish Chander Ph.D. (Purdue), FNA. Date of birth: 6 July 1935. Specialization: Thermodynamics of Biopolymers & Surfactants in Solutions and Solute-Solvent Interactions Address: 186, SFS Apartments, Hauz Khas, New Delhi 110 016, U.T.. Contact: Residence: (011) 2656 4519. Mobile: 92137 36359

  3. Datta, Prof. Swapan Kumar

    Indian Academy of Sciences (India)

    Datta, Prof. Swapan Kumar Ph.D. (Calcutta), FNA, FNASc, FNAAS, FTWAS. Date of birth: 28 January 1953. Specialization: Plant Biotechnology, Genetic Engineering, Crop Improvement Address: Vice Chancellor, Visva Bharati University, Santiniketan 731 235, W.B.. Contact: Office: (03463) 26 2451. Mobile: 87686 44777

  4. Agrawal, Prof. Manindra

    Indian Academy of Sciences (India)

    Elected: 2004 Section: Engineering & Technology. Agrawal, Prof. Manindra Ph.D. (IIT, Kanpur), FNAE, FNA, FNASc, FTWAS Council Service: 2016-. Date of birth: 20 May 1966. Specialization: Computational Complexity Theory and Computation Number Theory Address: Professor, Department of Computer Science, Indian ...

  5. Goodenough, Prof. John B

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1980 Honorary. Goodenough, Prof. John B. Date of birth: 25 July 1922. Address: Virginia H Cockrell Centennial, Professor of Engineering, University of Texat at Austin, ETC 9.184, Stop C2200, Austin, TX 78712, U.S.A.. Contact: Office: (+1-512) 471 1646. Email: jgoodenough@mail.utexas.edu.

  6. Arakeri, Prof. Vijay Hanumappa

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1991 Section: Engineering & Technology. Arakeri, Prof. Vijay Hanumappa Ph.D. (Caltech). Date of birth: 9 August 1945. Specialization: Cavitation, Hydrodynamics and Two-phase Flows Address: Department of Mechanical Engineering, Indian Institute of Science, Bengaluru 560 012, Karnataka

  7. Bjerknes, Prof. Vilheim Friman Koren

    Indian Academy of Sciences (India)

    Academy Public Lecture. Posted on 19 January 2018. Seasonal and Pandemic Influenza by Prof. Kanta Subbarao 25 January 2018 at 1600 hrs. Ground floor, Main auditorium, New Biological Sciences Building, IISc. Event Poster ...

  8. Varadhan, Prof. Srinivasa S R

    Indian Academy of Sciences (India)

    Varadhan, Prof. Srinivasa S R . Date of birth: 2 January 1940. Address: Department of Mathematics, Courant Institute, New York University, 251, Mercer Street, New York, NY 10012, U.S.A.. Contact: Office: (+1-212) 982 9883

  9. 5-FU Metabolism in Cancer and Orally-Administrable 5-FU Drugs

    Directory of Open Access Journals (Sweden)

    Iwao Sasaki

    2010-09-01

    Full Text Available 5-Fluorouracil (5-FU is a key anticancer drug that for its broad antitumor activity, as well as for its synergism with other anticancer drugs, has been used to treat various types of malignancies. In chemotherapeutic regimens, 5-FU has been combined with oxaliplatin, irinotecan and other drugs as a continuous intravenous infusion. Recent clinical chemotherapy studies have shown that several of the regimens with oral 5-FU drugs are not inferior compared to those involving continuous 5-FU infusion chemotherapy, and it is probable that in some regimens continuous 5-FU infusion can be replaced by oral 5-FU drugs. Historically, both the pharmaceutical industry and academia in Japan have been involved in the development of oral 5-FU drugs, and this review will focus on the current knowledge of 5-FU anabolism and catabolism, and the available information about the various orally-administrable 5-FU drugs, including UFT, S-1 and capecitabine. Clinical studies comparing the efficacy and adverse events of S-1 and capecitabine have been reported, and the accumulated results should be utilized to optimize the treatment of cancer patients. On the other hand, it is essential to elucidate the pharmacokinetic mechanism of each of the newly-developed drugs, to correctly select the drugs for each patient in the clinical setting, and to further develop optimized drug derivatives.

  10. Alfven, Prof. Hannes Olof Gosta

    Indian Academy of Sciences (India)

    Alfven, Prof. Hannes Olof Gosta Nobel Laureate (Physics) - 1970. Date of birth: 30 May 1908. Date of death: 2 April 1995. YouTube; Twitter ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  11. Krogh, Prof. Schack August Steenberg

    Indian Academy of Sciences (India)

    Krogh, Prof. Schack August Steenberg Nobel Laureate (Medicine) - 1920. Date of birth: 15 November 1874. Date of death: 13 September 1949 ... Summer Schools. Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach.

  12. Dirac, Prof. Paul Adrien Maurice

    Indian Academy of Sciences (India)

    Dirac, Prof. Paul Adrien Maurice Nobel Laureate (Physics) - 1933. Date of birth: 8 August 1902. Date of death: 20 October 1984. YouTube ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  13. Heymaans, Prof. Corneille Jean Francois

    Indian Academy of Sciences (India)

    Heymaans, Prof. Corneille Jean Francois Nobel Laureate (Medicine) - 1938. Date of birth: 28 March 1892. Date of death: 18 July 1968 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  14. Domagk, Prof. Gerhard Johannes Paul

    Indian Academy of Sciences (India)

    Domagk, Prof. Gerhard Johannes Paul Nobel Laureate (Medicine) - 1939. Date of birth: 30 October 1895. Date of death: 24 April 1964 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  15. Brumpt, Prof. Emile Joseph Alexandre

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1936 Honorary. Brumpt, Prof. Emile Joseph Alexandre. Date of birth: 10 March 1877. Date of death: 8 July 1951 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  16. Profile Interview: Prof. Rob Moodie

    African Journals Online (AJOL)

    health leaders such as Jonathan Mann and Daniel Tarantola. We moved back ... We were starting to slow down our moves by then and we ... Profile Interview: Prof. Rob Moodie. “Get up. Do good. Be good. Be.” foundation to use a tax on tobacco to buy out and replace tobacco industry sponsorship in sports and the arts, and.

  17. Rao, Prof. Paranandi Venkata Suryanarayana

    Indian Academy of Sciences (India)

    Elected: 1974 Section: Engineering & Technology. Rao, Prof. Paranandi Venkata Suryanarayana Ph.D. (Mumbai), FNA, FNASc, FNAE. Date of birth: 17 July 1936. Specialization: Computer Science & Speech Research, Natural Language Processing and Cursive Script Recognition Address: Flat No. 601, Vigyan, Sector 17, ...

  18. Bjerknes, Prof. Jacob Aall Bonneveie

    Indian Academy of Sciences (India)

    ... Mid Year Meetings · Discussion Meetings · Public Lectures · Lecture Workshops · Refresher Courses · Symposia · Live Streaming. Home; Fellowship. Fellow Profile. Elected: 1959 Honorary. Bjerknes, Prof. Jacob Aall Bonneveie. Date of birth: 2 November 1897. Date of death: 7 July 1975. YouTube; Twitter; Facebook; Blog ...

  19. Thomas, Prof. Sir John Meurig

    Indian Academy of Sciences (India)

    Thomas, Prof. Sir John Meurig FRS. Date of birth: 15 December 1932. Address: Department of Materials Science and, Metallurgy, New Museums Site, 27, Babbage Road, Cambridge CB3 0FS, U.K.. Contact: Office: (+44-1223) 33 4300. Fax: (+44-1223) 33 4567. Email: jmt2@cam.ac.uk. YouTube; Twitter; Facebook; Blog ...

  20. C V Prof. Yash Pal

    Indian Academy of Sciences (India)

    Elected: 1967 Section: Physics. Pal, Prof. Yash Ph.D. (MIT), FNA Council Service: 1974-76. Date of birth: 26 November 1926. Date of death: 24 July 2017. Specialization: Physics, Astrophysics, Space Technology and Communications Last known address: 11B, Super Delux Flats, Sector 15A, Noida 201 301, U.P.. YouTube ...

  1. Forssmann, Prof. Werner Theodor Otto

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1967 Honorary. Forssmann, Prof. Werner Theodor Otto Nobel Laureate (Medicine) - 1956. Date of birth: 29 August 1904. Date of death: 1 June 1979. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by ...

  2. Valiathan, Prof. Marthanda Varma Sankaran

    Indian Academy of Sciences (India)

    Valiathan, Prof. Marthanda Varma Sankaran Ch.M. (Liverpool), FRCS (England, Edinburgh & Canada), FRCP (London), D.Sc. (h.c.), FNA, FNASc, FNAE, FAMS, FTWAS Council Service: 1980-91; Vice-President: 1986-91. Date of birth: 24 May 1934. Specialization: Cardiac Surgery, Cardiovascular Materials and Ayurveda

  3. Rao, Prof. Manchanahalli Rangaswamy Satyanarayana

    Indian Academy of Sciences (India)

    Elected: 1988 Section: General Biology. Rao, Prof. Manchanahalli Rangaswamy Satyanarayana Ph.D. (IISc), FNA, FNASc, FTWAS, FAMS Council Service: 2013-; Vice President: 2013-. Date of birth: 21 January 1948. Specialization: RNA Biology, Molecular Biology, Cell Biology, Neurooncology Address: Honorary ...

  4. Mohan Ram, Prof. Holenarasipur Yoganarasimham

    Indian Academy of Sciences (India)

    Mohan Ram, Prof. Holenarasipur Yoganarasimham Ph.D. (Delhi), FNA, FNASc, FNAAS Council Service: 1983-88; Vice-President: 1986-88. Date of birth: 24 September 1930. Specialization: Plant Growth & Development and Economic Botany Address: No. 174, SFS DDA Flats, Mukherjee Nagar, Delhi 110 009, U.T.

  5. Krishna Murty, Prof. Achyutuni Venkata

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1993 Section: Engineering & Technology. Krishna Murty, Prof. Achyutuni Venkata Ph.D. (IISc). Date of birth: 10 October 1938. Specialization: Aerospace Engineering, Structural Mechanics, Composites and Smart Structures Address: No. 8, 5th Main, II Cross, NTI Layout, RMV II Stage, Nagashettyhalli, ...

  6. Das Gupta, Prof. Chanchal Kumar

    Indian Academy of Sciences (India)

    Elected: 1998 Section: General Biology. Das Gupta, Prof. Chanchal Kumar Ph.D. (Calcutta), FNASc, FNA. Date of birth: 9 November 1945. Specialization: Genetic Recombination and Protein Folding Address: EE-72/2, Sector II, Salt Lake, Kolkata 700 091, W.B.. Contact: Residence: (033) 4006 5279. Mobile: 90078 89857

  7. Murty, Prof. Sripada Venkata Satyasuryanarayana

    Indian Academy of Sciences (India)

    How to combat infectious diseases: The role of Science Academies · Academy Public Lecture and INSA–Leopoldina Lecture by Prof. Jörg Hacker, President, German Academy of Sciences Leopoldina. 4 December, 2017, 4 PM Faculty Hall, Indian Institute ...

  8. Baba, Prof. Chanduri Venkatasatya Kusumahara

    Indian Academy of Sciences (India)

    Elected: 1977 Section: Physics. Baba, Prof. Chanduri Venkatasatya Kusumahara Ph.D. (Mumbai). Date of birth: 2 October 1937. Date of death: 5 December 2006. Specialization: Nuclear Reactions Last known address: 8-3-169/113, 2D,, Pallavi Apartments, Siddarthnagar, Hyderabad 500 890. YouTube; Twitter; Facebook ...

  9. Levi-Civita, Prof. Tullio

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1938 Honorary. Levi-Civita, Prof. Tullio. Date of birth: 29 March 1873. Date of death: 29 December 1941. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. New Fellows and Honorary Fellow. Posted on 1 January 2018. List of Fellows and Honorary Fellow elected ...

  10. Dam, Prof. Carl Peter Henrik

    Indian Academy of Sciences (India)

    ... Meetings · Public Lectures · Lecture Workshops · Refresher Courses · Symposia · Live Streaming. Home; Fellowship. Fellow Profile. Elected: 1965 Honorary. Dam, Prof. Carl Peter Henrik Nobel Laureate (Medicine) - 1943. Date of birth: 21 February 1895. Date of death: 17 April 1976. YouTube; Twitter; Facebook; Blog ...

  11. Geim, Prof. Sir Andre Konstantin

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 2015 Honorary. Geim, Prof. Sir Andre Konstantin FRS. Date of birth: 21 October 1958. Address: Royal Society Research Professor, University of Manchester, Oxford Road, Manchester M13 9PL, UK Contact: Office: (+44-161) 275 4120. Email: geim@manchester.ac.uk. YouTube; Twitter; Facebook ...

  12. Hevesy, Prof. George Charles de

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1951 Honorary. Hevesy, Prof. George Charles de. Date of birth: 1 August 1885. Date of death: 5 July 1966. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on ...

  13. Kohlrausch, Prof. Karl Wilhelm Friedrich

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1939 Honorary. Kohlrausch, Prof. Karl Wilhelm Friedrich. Date of birth: 7 July 1884. Date of death: 17 September 1953. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies ...

  14. Blackett, Prof. Patrick Maynerd Stuart.

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1949 Honorary. Blackett, Prof. Patrick Maynerd Stuart. Nobel Laureate (Physics) - 1948. Date of birth: 17 November 1897. Date of death: 14 July 1974. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement ...

  15. Debye, Prof. Peter Joseph William

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1938 Honorary. Debye, Prof. Peter Joseph William Nobel Laureate (Chemistry) - 1936. Date of birth: 24 March 1884. Date of death: 2 November 1966. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement ...

  16. Joliot-Curie, Prof. Irene

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Joliot-Curie, Prof. Irene Nobel Laureate (Chemistry) - 1935. Date of birth: 12 September 1897. Date of death: 17 March 1956. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  17. Broglie, Prof. Louis Victor de

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1951 Honorary. Broglie, Prof. Louis Victor de. Nobel Laureate (Physics) - 1929. Date of birth: 15 August 1892. Date of death: 19 March 1987. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. New Fellows and Honorary Fellow. Posted on 1 January 2018. List of Fellows ...

  18. Bohr, Prof. Niels Henrik David

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Bohr, Prof. Niels Henrik David Nobel Laureate (Physics) - 1922. Date of birth: 7 October 1885. Date of death: 18 November 1962. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. New Fellows and Honorary Fellow. Posted on 1 January 2018.

  19. Patel, Prof. Chandra Kumar Naranbhai

    Indian Academy of Sciences (India)

    Elected: 1995 Section: Patel, Prof. Chandra Kumar Naranbhai. Date of birth: 2 July 1938. Address: President & CEO, Pranalytica Inc., 1101, Colorado Avenue, Santa Monica, CA 90401, U.S.A.. Contact: Office: (+1-310) 458 0808. Residence: (+1-310) 471 6505. Fax: (+1-310) 458 0171. Email: patel@pranalytica.com.

  20. Bhattacharya, Prof. Sudha Fellow profile

    Indian Academy of Sciences (India)

    Elected: 2001 Section: General Biology. Bhattacharya, Prof. Sudha Ph.D. (IARI, New Delhi), FNASc, FNA Council Service: 2016. Date of birth: 7 March 1952. Specialization: Molecular Biology, Molecular Parasitology and Genomics Address: Professor, School of Environmental Sciences, Jawaharlal Nehru University, New ...

  1. Guha-Mukherjee, Prof. Sipra

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1988 Section: Plant Sciences. Guha-Mukherjee, Prof. Sipra Ph.D. (Delhi), FNASc. Date of birth: 30 July 1938. Date of death: 15 September 2007. Specialization: Plant Molecular Biology, Plant Tissue Culture and Genetic Engineering Last known address: Garden Estate, M A 1/6-3C, Gurgaon 122 002.

  2. King, Prof. Sir David Anthony

    Indian Academy of Sciences (India)

    Elected: 1998 Honorary. King, Prof. Sir David Anthony Sc.D., FRS. Date of birth: 12 August 1939. Address: Chief Scientific Adivser & Head, Office of Science and Innovation, London SW1H 0ET, U.K.. Contact: Office: (+44-020) 7215 3821. Fax: (+44-020) 7215 0314. Email: mpst.king@dti.gsi.gov.uk, dak10@cus.cam.ac.uk.

  3. Spitzer IRS Observations of FU Orionis Objects

    Science.gov (United States)

    Green, J. D.; Hartmann, L.; Calvet, N.; Watson, D. M.; Ibrahimov, M.; Furlan, E.; Sargent, B.; Forrest, W. J.

    2006-09-01

    We present 5-35 μm spectra, taken with the Infrared Spectrograph (IRS) on the Spitzer Space Telescope, of five FU Orionis objects: FU Ori, V1515 Cyg, V1057 Cyg, BBW 76, and V346 Nor. All but V346 Nor reveal amorphous silicate grains in emission at 10 and 20 μm, and show water-vapor absorption bands at 5.8 and 6.8 μm and SiO or possibly methane absorption at 8 μm. These absorption features closely match these bands in model stellar photospheres-signs of the gaseous photospheres of the inner regions of these objects' accretion disks. The continuum emission at 5-8 μm is also consistent with such disks, and, for FU Orionis and BBW 76, longer wavelength emission may be fit by a model that includes moderate disk flaring. V1057 Cyg and V1515 Cyg have much more emission at longer wavelengths than the others, perhaps evidence of a substantial remnant of their natal, infalling envelopes.

  4. In Memoriam- Prof. Dr. Andries Willem Lategan

    Directory of Open Access Journals (Sweden)

    S. P. Ligthelm

    1965-03-01

    Full Text Available Hierdie Curriculum Vitae sou voorgelees gewees het met die inougurele rede van wyle prof. dr. A. W. Lategan met die aanvaarding van 'n ereprofessoraat aan die P.U. vir C.H.O. op 29 Oktober 1965. Prof. Lategan is op 23 Oktober 1965 oor- lcde. Sy inougurele rede verskyn as ’n bylaag in hierdie uit- gawe.

  5. The FU gene and its possible protein isoforms

    Directory of Open Access Journals (Sweden)

    Nöthen Markus M

    2004-07-01

    Full Text Available Abstract Background FU is the human homologue of the Drosophila gene fused whose product fused is a positive regulator of the transcription factor Cubitus interruptus (Ci. Thus, FU may act as a regulator of the human counterparts of Ci, the GLI transcription factors. Since Ci and GLI are targets of Hedgehog signaling in development and morphogenesis, it is expected that FU plays an important role in Sonic, Desert and/or Indian Hedgehog induced cellular signaling. Results The FU gene was identified on chromosome 2q35 at 217.56 Mb and its exon-intron organization determined. The human developmental disorder Syndactyly type 1 (SD1 maps to this region on chromosome 2 and the FU coding region was sequenced using genomic DNA from an affected individual in a linked family. While no FU mutations were found, three single nucleotide polymorphisms were identified. The expression pattern of FU was thoroughly investigated and all examined tissues express FU. It is also clear that different tissues express transcripts of different sizes and some tissues express more than one transcript. By means of nested PCR of specific regions in RT/PCR generated cDNA, it was possible to verify two alternative splicing events. This also suggests the existence of at least two additional protein isoforms besides the FU protein that has previously been described. This long FU and a much shorter isoform were compared for the ability to regulate GLI1 and GLI2. None of the FU isoforms showed any effects on GLI1 induced transcription but the long form can enhance GLI2 activity. Apparently FU did not have any effect on SUFU induced inhibition of GLI. Conclusions The FU gene and its genomic structure was identified. FU is a candidate gene for SD1, but we have not identified a pathogenic mutation in the FU coding region in a family with SD1. The sequence information and expression analyses show that transcripts of different sizes are expressed and subjected to alternative splicing

  6. Frey-Wyssling, Prof. Albert Friedrich

    Indian Academy of Sciences (India)

    Academy Public Lecture. Posted on 19 January 2018. Seasonal and Pandemic Influenza by Prof. Kanta Subbarao 25 January 2018 at 1600 hrs. Ground floor, Main auditorium, New Biological Sciences Building, IISc. Event Poster ...

  7. Commemorating the passing of Prof. Kazuo Akiyama

    National Research Council Canada - National Science Library

    Masami Taniguchi

    2015-01-01

    On November 3, 2014, Prof. Kazuo Akiyama, who was the Director of Sagamihara National Hospital, Kanagawa, Japan and had served as the President of the Japanese Society of Allergology for two terms, passed away...

  8. The Relationship of Acculturation Strategies to Resilience: The Moderating Impact of Social Support among Qiang Ethnicity following the 2008 Chinese Earthquake.

    Science.gov (United States)

    Han, Li; Berry, John W; Zheng, Yong

    2016-01-01

    International research has mostly confirmed the positive association between acculturation strategies and resilience in ethnic groups, but the mediating and moderating mechanisms underlying the relationships are still under-investigated. The present study aimed to investigate the associations between acculturation strategies (based on two cultural identities) and resilience of 898 Qiang ethnicity volunteers (mean age = 29.5), especially exploring the mediating and moderating effects of personality, spiritual belief and social support on the relationship between acculturation strategy (using two cultural identities as latent variables in model analysis) and resilience following the occurrence of 2008 Wenchuan earthquake in Sichuan, taking such mechanisms into account. Results were as follows: (1) All variable presented significant positive correlations; (2) Consistent with the mediating hypotheses, personality and spiritual beliefs played a partial mediating role in the relationship between two cultural identities and resilience; (3) High or low level of perceived social support had a moderating effect on cultural identities and resilience; (4) The integration strategy was the most optimal style to promote the development of resilience, but marginalization was the least effective style.

  9. Cellular response to 5-fluorouracil (5-FU in 5-FU-resistant colon cancer cell lines during treatment and recovery

    Directory of Open Access Journals (Sweden)

    Kravik Katherine L

    2006-05-01

    Full Text Available Abstract Background Treatment of cells with the anti-cancer drug 5-fluorouracil (5-FU causes DNA damage, which in turn affects cell proliferation and survival. Two stable wild-type TP53 5-FU-resistant cell lines, ContinB and ContinD, generated from the HCT116 colon cancer cell line, demonstrate moderate and strong resistance to 5-FU, respectively, markedly-reduced levels of 5-FU-induced apoptosis, and alterations in expression levels of a number of key cell cycle- and apoptosis-regulatory genes as a result of resistance development. The aim of the present study was to determine potential differential responses to 8 and 24-hour 5-FU treatment in these resistant cell lines. We assessed levels of 5-FU uptake into DNA, cell cycle effects and apoptosis induction throughout treatment and recovery periods for each cell line, and alterations in expression levels of DNA damage response-, cell cycle- and apoptosis-regulatory genes in response to short-term drug exposure. Results 5-FU treatment for 24 hours resulted in S phase arrests, p53 accumulation, up-regulation of p53-target genes on DNA damage response (ATF3, GADD34, GADD45A, PCNA, cell cycle-regulatory (CDKN1A, and apoptosis-regulatory pathways (FAS, and apoptosis induction in the parental and resistant cell lines. Levels of 5-FU incorporation into DNA were similar for the cell lines. The pattern of cell cycle progression during recovery demonstrated consistently that the 5-FU-resistant cell lines had the smallest S phase fractions and the largest G2(/M fractions. The strongly 5-FU-resistant ContinD cell line had the smallest S phase arrests, the lowest CDKN1A levels, and the lowest levels of 5-FU-induced apoptosis throughout the treatment and recovery periods, and the fastest recovery of exponential growth (10 days compared to the other two cell lines. The moderately 5-FU-resistant ContinB cell line had comparatively lower apoptotic levels than the parental cells during treatment and recovery

  10. Euler-Chelpin, Prof. Hans von

    Indian Academy of Sciences (India)

    Euler-Chelpin, Prof. Hans von. Nobel Laureate (Chemistry) - 1929. Date of birth: 15 February 1873. Date of death: 6 November 1964 ... Posted on 21 December 2017. ASTROPHYSICS: An Observational View of the Universe. Math Art and Design: MAD about Math, Math Education and Outreach. Math and Finance ...

  11. Prakasa Rao, Prof. Bhagavatula Lakshmi Surya

    Indian Academy of Sciences (India)

    Prakasa Rao, Prof. Bhagavatula Lakshmi Surya Ph.D. (Michigan State), FNA, FNASc. Date of birth: 6 October 1942. Specialization: Statistics Address: Ramanujan Chair Professor, CR Rao Advanced Institute of Mathematics,, Statistics & Computer Science, University of Hyderabad Campus, Hyderabad 500 046, A.P.

  12. Sewell, Prof. R.B. Seymour

    Indian Academy of Sciences (India)

    ... Mid Year Meetings · Discussion Meetings · Public Lectures · Lecture Workshops · Refresher Courses · Symposia · Live Streaming. Home; Fellowship. Fellow Profile. Elected: 1949 Honorary. Sewell, Prof. R.B. Seymour. Date of birth: 5 March 1880. Date of death: 10 February 1964. YouTube; Twitter; Facebook; Blog ...

  13. Laue, Prof. Max Theodor Felix von

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1954 Honorary. Laue, Prof. Max Theodor Felix von. Nobel Laureate (Physics) - 1914. Date of birth: 9 October 1897. Date of death: 24 April 1960. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the ...

  14. Prof. KS Krishnan and Crystal Magnetism

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 7; Issue 12. Prof. K S Krishnan and Crystal Magnetism. U S Ghosh. General Article Volume 7 Issue 12 December 2002 pp 65-70. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/007/12/0065-0070. Keywords.

  15. Sopory, Prof. Sudhir Kumar - IAS Fellow

    Indian Academy of Sciences (India)

    Elected: 1992 Section: Plant Sciences. Sopory, Prof. Sudhir Kumar Ph.D. (Delhi), FNA, FNASc, FNAAS, FTWAS Council Service: 2001-2006. Date of birth: 7 January 1948. Specialization: Molecular Plant Physiology and Plant Tissue Culture & Transformation Address: 584, Sector 14, Faridabad 121 007, Haryana Contact:

  16. Prasad, Prof. Yellapregada Venkata Rama Krishna

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1991 Section: Engineering & Technology. Prasad, Prof. Yellapregada Venkata Rama Krishna Ph.D. (IISc), FNA. Date of birth: 21 May 1944. Specialization: Deformation Processing, Process Modelling, Deterministic Chaos and Microstructural Control Address: B/2, Hospital Extension, Vinayaka Nagar, ...

  17. The Phonetical Properties of Fu-Yü Kyrgyz Language

    OpenAIRE

    KASAPOĞLU-ÇENGEL, Hülya

    2016-01-01

    The Kyrgyz people, who live in the Fu-Yü part of Manchuria and for whom their being the grandsons of the old Kyrgyz people and the Fu-Yü Kyrgyz language which is being spoken in the region are among the subjects, which the Turkology circles are interested in the recent years. The data, which are related to the subject are rather insufficient and are limited by the material, which has been published by Hu Zhenhua, E. Tenişev and Guy Imart. These data also have been the origin of the further r...

  18. Prof dr FJ van Zyl as sendingteoloog

    Directory of Open Access Journals (Sweden)

    D. J.C. vanWyk

    1989-01-01

    Full Text Available Prof Dr FJ van Zyl as mission theologian In this article, the theology of mission of Prof dr FJ van Zyl is being explored. This is done by way of his lectures in the Science of Mission at the University of Pretoria during 1960-1978 and also from articles in the magazines of the Nederduitsch Hervormde Kerk dating back approximately forty years. It is found that almost none of his dictions is outdated. The radical cataclysm in the theology of mission, especially after 1961, he sharply detected and exposed. His theology of mission is built on a very broad theological base which can be described as theology of the Word. To him mission is proclamation.

  19. High resolution spectroscopy of the new FU Orionis object BBW 76

    Science.gov (United States)

    Eisloeffel, J.; Hessman, F. V.; Mundt, R.

    1990-06-01

    High-resolution spectra of the new FU Orionis object BBW 76 are presented. Although the photometric outburst of this FU Orionis object could not be observed, its spectral characteristics clearly identify it as belonging to this class. BBW 76 shows Balmer line profiles typical for FU Orionis stars. Its absorption line spectrum and, in particular, the line widths are strikingly similar to that of FU Ori. Other similarities to FU Ori are the presence of an arclike nebula, and the FIR luminosities and color temperatures.

  20. Prof. Il-Hoi Kim: a tribute.

    Science.gov (United States)

    Huys, Rony

    2016-10-11

    Prof. Il-Hoi Kim was born during the Korean War on 28 February 1952 in Buan, North Jeolla Province (South Korea), near the coast of the Yellow Sea whose tidal flats would become one of his favourite sampling grounds during his scientific career. From an early age he developed an intense interest in natural history in general and marine biology in particular. He obtained his B.Sc. in 1974 at the Department of Biology Education, Gongju National College of Education. Between 1974 and 1976 he was conscripted into the South Korean military during which he progressed to the rank of lieutenant of artillery in the Reserve Officers' Training Corps (ROTC). After his graduation in 1980 at the Department of Zoology, Seoul National University, Il-Hoi Kim moved to the Department of Biology, Gangneung-Wonju National University on the East Sea coast where he was first appointed lecturer (1981) before taking up the position of assistant professor (1983), associate professor (1987) and full professor (1993). In 1985 he had previously completed his Ph.D. dissertation on Korean barnacles at Seoul National University under the supervision of the late Prof. Hoon Soo Kim, a pioneer in marine invertebrate taxonomy and renowned as the father of carcinology in Korea.

  1. Interview with Prof. Soeren M Bentzen (with english subtitles)

    CERN Multimedia

    Antonella del Rosso

    2012-01-01

    Interview with Prof. Soeren M Benzen, University of Wisconsin, Madison, on the role of physics biology and genomics in cancer treatment today. Interview avec le prof. Soeren Benzen, Université de Wisconsin, Madison, sur le role de la physique, la biologie et la genomique dans le traitement du cancer aujourd'hui.

  2. Prof. Frank Shu | Academy – Springer Nature chair | About IASc ...

    Indian Academy of Sciences (India)

    Academy – Springer Nature chair. Prof Frank Shu. Prof. Frank Shu. Shu is known for pioneering theoretical work in a diverse set of fields of astrophysics, including the origin of meteorites, the birth and early evolution of stars and the structure of spiral galaxies. One of his most highly-cited works is a 1977 seminal paper ...

  3. Prof. S. Dhawan | History | About IASc | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Prof. S. Dhawan. President from 1977 to 1979. Prof. S. Dhawan (1977-1979). Name: DHAWAN, Satish Elected 1970; Council Service: 1971-91; President: 1977-79; Vice-President: 1974-76. Member, Space Commission, Dept. of Space, Bengaluru Date of birth: 25 September 1920, Srinagar, Jammu & Kashmir

  4. 5FU resistance caused by reduced fluoro-deoxyuridine monophosphate and its reversal using deoxyuridine.

    Science.gov (United States)

    Mori, Ryutaro; Futamura, Manabu; Tanahashi, Toshiyuki; Tanaka, Yoshihiro; Matsuhashi, Nobuhisha; Yamaguchi, Kazuya; Yoshida, Kazuhiro

    2017-09-01

    The mechanism of 5-fluorouracil (5FU) resistance was investigated, focusing on the level of thymidylate synthase (TS) ternary complex formed with fluoro-deoxyuridine monophosphate (FdUMP). MKN45 and 5FU-resistant MKN45/F2R cells were treated with 5FU and fluoro-deoxyuridine (FdU) in combination with deoxyuridine (dU) and thymidine (dT). Subsequently, the levels of ternary complex were determined by western blotting and the cell viability was calculated using an MTT assay. MKN45/F2R cells exhibited 5FU resistance (56.2-fold relative to MKN45 cells), and demonstrated decreased orotate phosphoribosyltransferase (OPRT) and increased TS levels, requiring a higher concentration of 5FU to induce ternary complex formation than MKN45 cells. Following transfection of small interfering RNA against OPRT, MKN45 exhibited increased resistance to 5FU and decreased ternary complex formation subsequent to treatment with 5FU, indicating that decreased OPRT led to increased 5FU resistance. However, MKN45/F2R also exhibited resistance to FdU, which can be converted to FdUMP without OPRT, and there was decreased ternary complex formation after treatment with FdU, indicating that the 5FU-resistant cells had the ability to decrease intracellular FdUMP. The addition of dU and thymidine dT to 5FU promoted the formation of ternary complexes and reversed 5FU resistance in MKN45/F2R cells, although dT inhibited the efficacy of raltitrexed (another TS inhibitor). These results suggested that 5FU-resistant cells had the ability to reduce intracellular FdUMP irrespective of decreased OPRT, which led to resistance to 5FU. This resistance was then inhibited by treatment with dT or dU.

  5. WAVELET TRANSFORM ANALYSIS OF ELECTROMYOGRAPHY KUNG FU STRIKES DATA

    Directory of Open Access Journals (Sweden)

    Ana Carolina de Miranda Marzullo

    2009-11-01

    Full Text Available In martial arts and contact sports strikes are performed at near maximum speeds. For that reason, electromyography (EMG analysis of such movements is non-trivial. This paper has three main goals: firstly, to investigate the differences in the EMG activity of muscles during strikes performed with and without impacts; secondly, to assess the advantages of using Sum of Significant Power (SSP values instead of root mean square (rms values when analyzing EMG data; and lastly to introduce a new method of calculating median frequency values using wavelet transforms (WMDF. EMG data of the deltoid anterior (DA, triceps brachii (TB and brachioradialis (BR muscles were collected from eight Kung Fu practitioners during strikes performed with and without impacts. SSP results indicated significant higher muscle activity (p = 0.023 for the strikes with impact. WMDF results, on the other hand, indicated significant lower values (p = 0. 007 for the strikes with impact. SSP results presented higher sensitivity than rms to quantify important signal differences and, at the same time, presented lower inter-subject coefficient of variations. The result of increase in SSP values and decrease in WMDF may suggest better synchronization of motor units for the strikes with impact performed by the experienced Kung Fu practitioners

  6. Evolution of the FU Orionis Object BBW 76

    Science.gov (United States)

    Reipurth, Bo; Hartmann, Lee; Kenyon, Scott J.; Smette, Alain; Bouchet, Patrice

    2002-10-01

    We have carried out a long-term photometric and spectroscopic monitoring program of the southern FU Orionis-type object BBW 76 spanning the period from 1982 to 1997. BBW 76 has the same radial velocity as the small cloud toward which it is projected, and for which a kinematic distance of about 1.8 kpc has been derived. We have determined a large reddening of E(B-V)~0.7 for BBW 76. Optical and infrared spectra show the change toward later spectral type with increasing wavelength characteristic of FU Orionis stars and indicative of a hot luminous disk. High-resolution echelle spectra of BBW 76 show P Cygni profiles with extended blueshifted absorption troughs at the Hα and sodium lines from a neutral, supersonic wind. Comparison of such spectra obtained at six different epochs between 1985 and 1997 reveals major changes in these Hα and sodium line profiles. For a period of 10 years from 1985, the massive absorption troughs diminished in extent and depth, until by 1994 they had all but disappeared, while at the same time the blueshifted emission peak in the Hα line increased markedly in strength. However, when observed in 1997, the absorption had increased again and the emission had diminished. We interpret this in terms of an extended period during which accretion through a circumstellar disk decreased, with a resulting decrease in wind production. But the increased activity by 1997 shows that this is not a constant decay and that the star was not about to revert to its presumably original T Tauri stage. We monitored the star with optical photometry from 1983 to 1994, during which period it decreased almost monotonically in brightness by 0.2 mag in V. Infrared J, H, and K photometry from 1983 to 1991 shows a period of monotonic fading between 1984 and 1988, followed by more irregular behavior. In a search of the Harvard plate archives we have found a plate from the year 1900 on which BBW 76 is seen at approximately its present brightness, certainly not 2 mag

  7. FuGEFlow: data model and markup language for flow cytometry

    Directory of Open Access Journals (Sweden)

    Manion Frank J

    2009-06-01

    Full Text Available Abstract Background Flow cytometry technology is widely used in both health care and research. The rapid expansion of flow cytometry applications has outpaced the development of data storage and analysis tools. Collaborative efforts being taken to eliminate this gap include building common vocabularies and ontologies, designing generic data models, and defining data exchange formats. The Minimum Information about a Flow Cytometry Experiment (MIFlowCyt standard was recently adopted by the International Society for Advancement of Cytometry. This standard guides researchers on the information that should be included in peer reviewed publications, but it is insufficient for data exchange and integration between computational systems. The Functional Genomics Experiment (FuGE formalizes common aspects of comprehensive and high throughput experiments across different biological technologies. We have extended FuGE object model to accommodate flow cytometry data and metadata. Methods We used the MagicDraw modelling tool to design a UML model (Flow-OM according to the FuGE extension guidelines and the AndroMDA toolkit to transform the model to a markup language (Flow-ML. We mapped each MIFlowCyt term to either an existing FuGE class or to a new FuGEFlow class. The development environment was validated by comparing the official FuGE XSD to the schema we generated from the FuGE object model using our configuration. After the Flow-OM model was completed, the final version of the Flow-ML was generated and validated against an example MIFlowCyt compliant experiment description. Results The extension of FuGE for flow cytometry has resulted in a generic FuGE-compliant data model (FuGEFlow, which accommodates and links together all information required by MIFlowCyt. The FuGEFlow model can be used to build software and databases using FuGE software toolkits to facilitate automated exchange and manipulation of potentially large flow cytometry experimental data sets

  8. Prof. Dr. Johannes Christiaan Coetzee as opvoedkundige denker

    Directory of Open Access Journals (Sweden)

    J. J. Snyman

    1953-03-01

    Full Text Available Dit is met genoëe dat ek voldoen aan die versoek om kortliks ’n paar gedagtes uit te spreek oor die opvoedkunde, veral die Calvinistiese opvoedkunde en die opvoedkundige praktyk van prof. Coetzee.

  9. Prof. John Wood, Chief Executive Designate, Dr Gordon Walker, Directorate, Chief Executive, Prof. Ken J. Peach, Head of the Particle Physics Department, CLRC Rutherford Appleton Laboratory, United Kingdom

    CERN Document Server

    Patrice Loïez

    2001-01-01

    L. to. r.: Dr. Ian Wilson, CLIC Deputy Study Leader, Prof. Ken J. Peach, Head of the Particle Physics Department, Prof. John Wood, Chief Executive Designate, Dr. Gordon Walker, Directorate, Chief Executive

  10. Mitomycin-C and 5- FU in ophthalmology: review article

    Directory of Open Access Journals (Sweden)

    M Jabbarvand Behrouz

    2009-03-01

    Full Text Available "nThe response of living tissues to the surgical trauma is associated with varying degrees of tissue repair and involves two distinct processes including replacement and regeneration. Replacement results in scar tissue formation instead of restoration of the normal architecture. However, regeneration leads to restoration of the original architecture leaving no sign of injury. Anti-proliferative agents are used to inhibit tissue responses to surgical trauma. Among them mitomycin- C and 5- FU had gained increasing applications in ophthalmic surgeries, including filtering glaucoma surgeries, laser vision correction with excimer laser by ablative surface refractive surgery, reconstructive surgeries for ocular surface disorders and removal of neoplastic tissues and secondary operations on nasolacrimal ducts. In this review article, the various aspects of applications of these agents including their mechanism of action, function, mode of application and complications in different ophthalmology fields are discussed.

  11. Multiple shoot induction and rooting of Paeonia lactiflora 'Da Fu Gui ...

    African Journals Online (AJOL)

    Shoot height at the time of inoculation had a great effect on proliferation and growth of 'Da Fu Gui'. Putrescine (Put) (0.5 to 5.0 mg l-1) prevented rooting of 'Da Fu Gui' but it favored the development of roots. Highest rooting percentage was observed on half-strength MS medium (double-strength Ca2+) supplemented with 1 ...

  12. γ-Tocotrienol prevents 5-FU-induced reactive oxygen species production in human oral keratinocytes through the stabilization of 5-FU-induced activation of Nrf2.

    Science.gov (United States)

    Takano, Hideyuki; Momota, Yukihiro; Kani, Kouichi; Aota, Keiko; Yamamura, Yoshiko; Yamanoi, Tomoko; Azuma, Masayuki

    2015-04-01

    Chemotherapy-induced oral mucositis is a common adverse event in patients with oral squamous cell carcinoma, and is initiated through a variety of mechanisms, including the generation of reactive oxygen species (ROS). In this study, we examined the preventive effect of γ-tocotrienol on the 5-FU-induced ROS production in human oral keratinocytes (RT7). We treated RT7 cells with 5-FU and γ-tocotrienol at concentrations of 10 µg/ml and 10 nM, respectively. When cells were treated with 5-FU alone, significant growth inhibition was observed as compared to untreated cells. This inhibition was, in part, due to the ROS gene-rated by 5-FU treatment, because N-acetyl cysteine (NAC), a ROS scavenger, significantly ameliorated the growth of RT7 cells. γ-tocotrienol showed no cytotoxic effect on the growth of RT7 cells. Simultaneous treatment of cells with these agents resulted in the significant recovery of cell growth, owing to the suppression of ROS generation by γ-tocotrienol. Whereas 5-FU stimulated the expression of NF-E2-related factor 2 (Nrf2) protein in the nucleus up to 12 h after treatment of RT7 cells, γ-tocotrienol had no obvious effect on the expression of nuclear Nrf2 protein. Of note, the combined treatment with both agents stabilized the 5-FU-induced nuclear Nrf2 protein expression until 24 h after treatment. In addition, expression of Nrf2-dependent antioxidant genes, such as heme oxygenase-1 (HO-1) and quinone oxidoreductase-1 (NQO-1), was significantly augmented by treatment of cells with both agents. These findings suggest that γ-tocotrienol could prevent 5-FU-induced ROS generation by stabilizing Nrf2 activation, thereby leading to ROS detoxification and cell survival in human oral keratinocytes.

  13. In Memoriam: Prof. Dr Dragutin Djurovic (1937-2013)

    Science.gov (United States)

    2013-12-01

    Prof. dr Dragutin Djurovic was born in Guca, Serbia, on December 20, 1937. He completed his primary and secondary education in Guca and Cacak. In the period 1956-1958, he studied at the General Military Academy in Belgrade. He enrolled at the Faculty of Sciences and Mathematics - Astronomy Group in 1958 and graduated in 1963. After graduation he went to study visits to Paris (1966) and Bruxelles (1972 and 1975). He obtained his MSc degree in 1970 from the University of Belgrade with a thesis entitled "Application of different types of telescopes for astronomical determination of time". His supervisor for the master thesis was Prof. Zaharije Brkic. Dragutin Djurovic defended his PhD thesis "Contribution to determination of Earth-rotation variations and polar motion" at the University of Belgrade in 1974. Most of the thesis-related research was done in Bruxelles during 1972 under the supervision of Prof. Paul Melchior.

  14. Ezra Pound and Du Fu: Gazing at Mt. Tai

    Directory of Open Access Journals (Sweden)

    Kent Su

    2017-08-01

    Full Text Available Confined to a six-by-six-foot outdoor steel cage, Ezra Pound saw a series of mountain hills from a few miles to the east of Pisa. The poet compared one of these small 800-metre hills to the sacred Chinese Mt. Tai, which becomes the most common geographical name in The Pisan Cantos. Pound’s poetic summoning of this particular mountain is related to the fact that Mt. Tai is historically and culturally connected to the philosophy of Confucius, who personally ascended the mountain several times. Pound, as a devout Confucian disciple, closely follows the philosophical doctrines and attempts to mentally trace the footsteps of Confucius. This paper will argue how Pound’s poetic evocation of the mountain shares a striking similarity to an eighth-century Chinese poem called “Gazing at Mt. Tai,” which was written by the famous literatus - Du Fu 杜甫(712 – 770 . In spite of living in two completely different eras and countries, Pound’s and Du Fu’s reference to Mt. Tai demonstrates the confluence of their poetic spirits. Neither of them ascended mountain personally. They instead made use of their poetic imagination to follow the paths of Confucius and perceived the mountain as an earthly paradise, one which represents tranquillity and serenity away from the moral and physical corruption of the external world.

  15. Curriculum Vitae of Prof. Dr. Gürer GÜLSEVİN and Prof. Dr. Ayşe İLKER’s Impressions About Him Prof. Dr. Gürer GÜLSEVİN’in Özgeçmişi ve Prof. Dr. Ayşe İLKER’in Onun Hakkındaki İzlenimleri

    Directory of Open Access Journals (Sweden)

    Özgür AY

    2011-01-01

    Full Text Available Curriculum Vitae of Prof. Dr. Gürer GÜLSEVİN and Prof. Dr. Ayşe İLKER’s Impressions About Him Prof. Dr. Gürer GÜLSEVİN’in Özgeçmişi ve Prof. Dr. Ayşe İLKER’in Onun Hakkındaki İzlenimleri

  16. Cardioprotective effects of Dan-Yang-Fu-Xin decoction on chronic ...

    African Journals Online (AJOL)

    Cardioprotective effects of Dan-Yang-Fu-Xin decoction on chronic heart failure in rats. ... including fractional shortening (FS), ejection fraction (EF), heart rate (HR) ... in body weight and increase in cardiac weight (p < 0.05) induced by CHF.

  17. Asynchronous Sensor fuSion for Improved Safety of air Traffic (ASSIST) Project

    Data.gov (United States)

    National Aeronautics and Space Administration — SSCI proposes to develop, implement and test a collision detection system for unmanned aerial vehicles (UAV), referred to as the Asynchronous Sensor fuSion for...

  18. Ueber die von Prof. Dr. A. Gerstaecker beschriebenen Ascalaphidae (Neuroptera)

    NARCIS (Netherlands)

    Weele, van der H.W.

    1906-01-01

    In den Mitth. des naturw. Ver. für Neuvorpomm. und Rügen, Band XVI, XIX, XX. und XXV, hat Gerstaecker eine Reihe neuer Arten Planipennia beschrieben, von welchen ich durch die Freundlichkeit seines Nachfolgers Prof. G. W. Müller in Greifswald die Ascalaphiden zur Untersuchung bekommen habe. Obschon

  19. Editorial Prof Lundgren's significant contribution to SAJAA and its ...

    African Journals Online (AJOL)

    Prof Chris Lundgren was the Editor-in-Chief of the Southern. African Journal of Anaesthesia and Analgesia (SAJAA) for a remarkable 14 years from 2001-2015. Under her excellent guidance, the journal has developed and grown to the point that the Academy of Science for South Africa's (ASSAf) review of scholarly ...

  20. Prof. Dr. A. J. H. van der Walt

    Directory of Open Access Journals (Sweden)

    J. C. Coetzee

    1956-03-01

    Full Text Available Prof. Van der Walt, die eerste prinsipaal van die Universiteit van Suid-Afrika en vroeër ook die eerste professor in die Geskiedenis aan die Potchefstroomse Universiteitskollege vir Christelike Hoër Onderwys, tree op 31 Maart 1956 uit die aktiewe universitêre diens.

  1. Itinerary for Prof. Nitash Balsara Arrival in Mumbai, November 4 ...

    Indian Academy of Sciences (India)

    RV

    2014-11-11

    Arrival in Mumbai, November 4. November 4-10 in and around Mumbai, will give lecture in IIT Bombay. November 11-15, in and around Kanpur, Prof Ashutosh Sharma will organize program. November 11, 2014. Mumbai-Lucknow: Air India AI-625; departs 10:30, reaches. 12:40. November 15, 2014. Lucknow-Bangalore.

  2. FuMicro: A Fused Microarchitecture Design Integrating In-Order Superscalar and VLIW

    Directory of Open Access Journals (Sweden)

    Yumin Hou

    2016-01-01

    Full Text Available This paper proposes FuMicro, a fused microarchitecture integrating both in-order superscalar and Very Long Instruction Word (VLIW in a single core. A processor with FuMicro microarchitecture can work under alternative in-order superscalar and VLIW mode, using the same pipeline and the same Instruction Set Architecture (ISA. Small modification to the compiler is made to expand the register file in VLIW mode. The decision of mode switch is made by software, and this does not need extra hardware. VLIW code can be exploited in the form of library function and the users will be exposed under only superscalar mode; by this means, we can provide the users with a convenient development environment. FuMicro could serve as a universal microarchitecture for it can be applied to different ISAs. In this paper, we focus on the implementation of FuMicro with ARM ISA. This architecture is evaluated on gem5, which is a cycle accurate microarchitecture simulation platform. By adopting FuMicro microarchitecture, the performance can be improved on an average of 10%, with the best performance improvement being 47.3%, compared with that under pure in-order superscalar mode. The result shows that FuMicro microarchitecture can improve Instruction Level Parallelism (ILP significantly, making it promising to expand digital signal processing capability on a General Purpose Processor.

  3. Prof. Nanopoulos visits Hill Primary School in Greece

    CERN Multimedia

    2014-01-01

    This video is an extract of a reportage broadcasted by SKAI TV in Greece about the visit of Prof. Dimitri Nanopoulos to Hill Primary School, the oldest operating school in Greece. The video describes a breakthrough education programme aimed at introducing big ideas in physics, particle physics and cosmology to K-6 students through a pedagogical approach that promotes inquiry, creativity and hands-on experimentation with the use everyday materials.

  4. Formulation and investigation of 5-FU nanoparticles with factorial design-based studies.

    Science.gov (United States)

    Bozkir, Asuman; Saka, Ongun Mehmet

    2005-10-01

    This study describes an orthogonal experimental design to optimize the formulation of 5-fluorouracil (5-FU) loaded poly D,L (lactide-co-glycolide) (PLGA) nanoparticles (5FU-NP) by a nanoprecipitation-solvent displacement technique. The type of surfactant, amount of acetone and molecular weight of the polymer with three levels of each factor were selected and arranged in an L18(3(5)) orthogonal experimental table. From the statistical analysis of the data polynominal equations were generated. Optimized formulations have the particle size ranging from 160 to 250 nm. Smallest nanoparticles (161+/-1.22 nm) were obtained using Resomer PLGA 755 and pluronic F-68 with 10 ml acetone amount. Under these conditions the 5-FU entrapment percentage was maximum 78.30%, suggesting 5-FU might be entrapped and adsorbed on the nanoparticle surface. In vitro release of three formulations with maximum drug entrapment efficiency and minimum particle size, were also investigated by release kinetics. According to the determined coefficients, release data fit to Higuchi's diffusion kinetics. The in vitro release of 5FU-NP in phosphate buffered saline (PBS, pH 7.4) is suggested to be controlled by a combination of diffusion with slow and gradual erosion of the particles. Also, the antimicrobial activity was observed even on the end of seventh day with all formulations.

  5. Kung-fu versus swimming training and the effects on balance abilities in young adolescents.

    Science.gov (United States)

    Baccouch, Rym; Rebai, Haithem; Sahli, Sonia

    2015-11-01

    Our purpose is to investigate the static balance control of young adolescents practicing kung-fu and swimming in order to find out which of these physical activities is the most effective in developing specific balance abilities in young adolescents. Comparative experimental study. University laboratory research. Three groups of 11-13-year-old boys (12 practicing Kung-Fu, 12 practicing swimming and 12 controls). Center of pressure (CoP) excursions were registered in upright bipedal and unipedal stances on a stabilometric force platform in eyes open (EO) and eyes closed (EC) conditions. Kung-fu practitioners control their balance (P balance control in the EO condition. However, swimming training developed (P balance control in both EO and EC conditions. The swimmers showed a lower reliance on vision (P balance abilities that could be important for improving and maintaining optimal health. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. Overview of the Fusion Z-Pinch Experiment FuZE

    Science.gov (United States)

    Weber, T. R.; Shumlak, U.; Nelson, B. A.; Golingo, R. P.; Claveau, E. L.; McLean, H. S.; Tummel, K. K.; Higginson, D. P.; Schmidt, A. E.; UW/LLNL Team

    2016-10-01

    Previously, the ZaP device, at the University of Washington, demonstrated sheared flow stabilized (SFS) Z-pinch plasmas. Instabilities that have historically plagued Z-pinch plasma confinement were mitigated using sheared flows generated from a coaxial plasma gun of the Marshall type. Based on these results, a new SFS Z-pinch experiment, the Fusion Z-pinch Experiment (FuZE), has been constructed. FuZE is designed to investigate the scaling of SFS Z-pinch plasmas towards fusion conditions. The experiment will be supported by high fidelity physics modeling using kinetic and fluid simulations. Initial plans are in place for a pulsed fusion reactor following the results of FuZE. Notably, the design relies on proven commercial technologies, including a modest discharge current (1.5 MA) and voltage (40 kV), and liquid metal electrodes. Supported by DoE FES, NNSA, and ARPA-E ALPHA.

  7. Evolutionism through Chinese Eyes: Yan Fu, Ma Junwu and Their translations of Darwinian Evolutionism

    Directory of Open Access Journals (Sweden)

    Tsing-song Vincent Shen

    2015-04-01

    Full Text Available The huge impact that Darwinian Evolutionism has effected over Chinese intellectuals through Yan Fu's translation of Huxley's "Evolution and Ethics" into the Tianyanlun, is in fact based on Chinese traditional worldview on the one hand and the novel ideas it brings to the Chinese mind facing the challenge of transition. However, Yan Fu's translation is not as scientific as it should be when dealing with Huxley's discourse. Ma Junwu's translation of Darwin's "On the Origin of Species" attempts to be more scientific, in an effort to supply exact scientific terms and discourse in Chinese. However, at the end it is social Darwinism that has won the mind of the Chinese people. This paper analyses the ideas in Chinese past that leads to Chinese perception of Darwimism evolutionism and examines the ways it has been translated by Yan Fu and Ma Junwu.  

  8. MTHFR polymorphisms and 5-FU-based adjuvant chemotherapy in colorectal cancer

    DEFF Research Database (Denmark)

    Afzal, Shoaib; Jensen, S; Vainer, B

    2009-01-01

    >T and 1298A>C polymorphisms were not associated with survival or relapse-free survival (P > 0.2). The 677 CC genotype was associated to toxicity (odds ratio = 1.83, P = 0.01). Conclusions: The MTHFR 677C>T and 1298A>C polymorphisms probably do not predict efficacy of adjuvant 5-FU treatment in colorectal...... cancer after complete resection; however, the 677C>T polymorphism may be associated with lower toxicity in 5-FU treatment. Implementation of SNP analysis for these polymorphisms for individualized treatment is premature....

  9. Wheat germ allutinin functionalized crosslinked polyelectrolyte microparticles for local colon delivery of 5-FU

    DEFF Research Database (Denmark)

    Glavas-Dodov, Marija; Steffansen, Bente; Crcarevska, Maja

    2013-01-01

    We have previously reported the development and characterisation of wheat germ agglutinin (WGA)-functionalised chitosan-Ca-alginate (CTS-Ca-ALG) microparticles (MPs) loaded with acid-resistant particles of 5-fluorouracil (5-FU). In the present work, our goal was to evaluate the potential of these......We have previously reported the development and characterisation of wheat germ agglutinin (WGA)-functionalised chitosan-Ca-alginate (CTS-Ca-ALG) microparticles (MPs) loaded with acid-resistant particles of 5-fluorouracil (5-FU). In the present work, our goal was to evaluate the potential...

  10. A long-term photometric study of the FU Orionis star V 733 Cep

    OpenAIRE

    Peneva, S. P.; Semkov, E. H.; Munari, U.; Birkle, K.

    2010-01-01

    The FU Orionis candidate V733 Cep was discovered by Roger Persson in 2004. The star is located in the dark cloud L1216 close to the Cepheus OB3 association. Because only a small number of FU Orionis stars have been detected to date, photometric and spectral studies of V733 Cep are of great interest. The studies of the photometrical variability of PMS stars are very important to the understanding of stellar evolution. The main purpose of our study is to construct a long-time light curve of V73...

  11. Attenuated Cardiac Mitochondrial-Dependent Apoptotic Effects by Li-Fu Formula in Hamsters Fed with a Hypercholesterol Diet

    Directory of Open Access Journals (Sweden)

    Wei-Wen Kuo

    2011-01-01

    Full Text Available Apoptosis involves in the pathogenesis of various cardiac abnormalities. This study intends to evaluate the effects of Li-Fu formula on cardiac apoptosis induced by hyper-cholesterol diet. Twenty-four male Golden Syrian hamsters were randomly divided into Control, Cholesterol and Li-Fu formula groups. Histopathological analysis, western blotting and terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL assays were performed to measure the effects of Li-Fu formula on left ventricle. Significantly reduced TUNEL-positive cells and mitochondria- dependent apoptosis were observed in the left ventricle of hamsters from Li-Fu formula group compared to the Cholesterol group. Additionally, induced cardiac insulin like growth factor I receptor (IGFIR-dependent survival pathway was detected in the Li-Fu formula group compared to the Cholesterol group. Besides, minor fibrosis, increased collagen deposition, and myofibril disarray was detected in the Cholesterol group, whereas the reductions of collagen deposition and myofibril disarray were observed in the Li-Fu formula group. This study demonstrated that Li-Fu formula not only reduced the mitochondria-dependent apoptosis and fibrosis, but also enhanced the IGF-I survival pathway in the left ventricle from high cholesterol-fed hamsters. We suggest the protective effects of Li-Fu formula on cardiac apoptosis and therapeutic potentials against cardiovascular disease.

  12. FuMa: reporting overlap in RNA-seq detected fusion genes.

    Science.gov (United States)

    Hoogstrate, Youri; Böttcher, René; Hiltemann, Saskia; van der Spek, Peter J; Jenster, Guido; Stubbs, Andrew P

    2016-04-15

    A new generation of tools that identify fusion genes in RNA-seq data is limited in either sensitivity and or specificity. To allow further downstream analysis and to estimate performance, predicted fusion genes from different tools have to be compared. However, the transcriptomic context complicates genomic location-based matching. FusionMatcher (FuMa) is a program that reports identical fusion genes based on gene-name annotations. FuMa automatically compares and summarizes all combinations of two or more datasets in a single run, without additional programming necessary. FuMa uses one gene annotation, avoiding mismatches caused by tool-specific gene annotations. FuMa matches 10% more fusion genes compared with exact gene matching due to overlapping genes and accepts intermediate output files that allow a stepwise analysis of corresponding tools. The code is available at: https://github.com/ErasmusMC-Bioinformatics/fuma and available for Galaxy in the tool sheds and directly accessible at https://bioinf-galaxian.erasmusmc.nl/galaxy/ y.hoogstrate@erasmusmc.nl or a.stubbs@erasmusmc.nl Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  13. Cardioprotective effects of Dan-Yang-Fu-Xin decoction on chronic ...

    African Journals Online (AJOL)

    Purpose: To evaluate the cardioprotective effects and possible mechanisms of Dan-Yang-Fu-Xin decoction (DYFX) in a rat chronic heart failure (CHF). Methods: A CHF rat model induced by ligation of the left anterior descending coronary artery was used to investigate the cardioprotective effects of DYFX. After intragastric ...

  14. Variability of OI 090.4 ShaoMing Hu , Xu Chen & DiFu Guo

    Indian Academy of Sciences (India)

    2009-12-20

    Dec 20, 2009 ... ShaoMing Hu. ∗. , Xu Chen & DiFu Guo. School of Space Science and Physics, Shandong University, Weihai,. 180 Cultural West Road, Shandong 264209, China. ∗ e-mail: husm@sdu.edu.cn. Abstract. OI 090.4 was monitored on 21 nights from 2006 to 2012 for studying the variability. Strong variations ...

  15. Fungal community succession and major components change during manufacturing process of Fu brick tea.

    Science.gov (United States)

    Li, Qin; Huang, Jianan; Li, Yongdi; Zhang, Yiyang; Luo, Yu; Chen, Yuan; Lin, Haiyan; Wang, Kunbo; Liu, Zhonghua

    2017-07-31

    Fu brick tea is a unique post-fermented tea product which is fermented with microorganism during the manufacturing process. Metabolic analysis showed that most metabolites content were decreased during the manufacturing process of Fu brick tea, except GA (gallic acid). Illumina MiSeq sequencing of ITS gene amplicons was applied to analyze the fungal community succession. The genera Aspergillus, Cyberlindnera and Candida were predominant at the early stage of manufacturing process (from "primary dark tea" to "fermentation for 3 days"), but after the stage of "fermentation for 3 days" only Aspergillus was still dominated, and maintain a relatively constant until to the end of manufacturing process. The effects of metabolites on the structure of the fungal community were analyzed by redundancy analysis (RDA) and variation partitioning analysis (VPA). The results indicated that GCG (gallocatechin gallate), EGCG (epigallocatechin gallate) and GA as well as the interactions among them were the most probably ones to influence, or be influenced by the fungal communities during the fermentation process of Fu brick tea. This study revealed fungal succession, metabolite changes and their relationships, provided new insights into the mechanisms for manufacturing process of Fu brick tea.

  16. *J.S., Ogeh and E. Ukodo Fu ll L eng th R esearch A rticle

    African Journals Online (AJOL)

    can also make a basis for defining different management zones on a field or an area. Based on the above the objective of this work was to examine the variability of some soil physical and chemical properties from three (3) pedons, in a toposequence in the University of Benin, Edo State, Nigeria. Fu ll L eng th. R esearch. A.

  17. [Mining analysis on composition and medication of menstruation prescriptions in Fu Qingzhu's Obstetrics and Gynecology].

    Science.gov (United States)

    Zhu, Jia-qing; Che, Yu-xia

    2015-04-01

    In this paper, menstruation prescriptions were selected from "Fu Qingzhu's Obstetrics and Gynecology" and analyzed by using GRI algorithm, correlation analysis, hierarchical clustering method through SPSS, Clementine and traditional Chinese medicine (TCM) inheritance auxiliary systems, in order to screen out 15 menopathy prescriptions, which involve 45 traditional Chinese medicine herbs. In the study, blood-tonifying and qi-tonifying herbs were found to be frequent in the prescriptions. The most frequent single herb was white paeony root, accounting for 9.6% in the total number of prescriptions; The most frequent herb pairs were white paeony root-radix rehmanniae preparata and paeony root-angelica sinensis. Among Fu Shan's menopathy prescriptions, 61 herbal pairs showed a correlation coefficient exceeding 0.05, which evolved into 16 pairs of core combinations. The analysis showed that menopathy prescriptions in volume 1 of "Fu Qingzhu's Obstetrics and Gynecology" focused on tonic traditional Chinese medicines involving liver, spleen and kidney and were adjusted according to changes in qi, blood, cold, hot and wet, which could provide a specific reference for further studies on Fu Shan's academic thoughts and traditional Chinese medicine clinical treatment of menopathy.

  18. Protective effect of dexamethasone on 5-FU-induced oral mucositis in hamsters.

    Directory of Open Access Journals (Sweden)

    Susana Barbosa Ribeiro

    Full Text Available Oral mucositis (OM is an important side effect of cancer treatment, characterized by ulcerative lesions in the mucosa of patients undergoing radiotherapy or chemotherapy, which has marked effects on patient quality of life and cancer therapy continuity. Considering that few protocols have demonstrated efficacy in preventing this side effect, the aim of this study was to examine the effect of dexamethasone (DEX on OM induced by 5-fluorouracil (5-FU in hamsters by studying signaling pathways. OM was induced in hamsters by 5-FU followed by mechanical trauma (MT on day 4. On day 10, the animals were euthanized. The experimental groups included saline, MT, 5-FU, and DEX (0.25, 0.5, or 1 mg/kg. Macroscopic, histopathological, and immunohistochemical analyses as well as immunofluorescence experiments were performed on the oral mucosa of the animals. The oral mucosal samples were analyzed by enzyme-linked immunosorbent assays, and quantitative real-time polymerase chain reaction (qPCR. DEX (0.5 or 1 mg/kg reduced inflammation and ulceration of the oral mucosa of hamsters. In addition, DEX (1 mg/kg reduced the cytokine levels of tumor necrosis factor (TNF-α, interleukin (IL-1β, and macrophage migration inhibitory factor (MIF. DEX (1 mg/kg also reduced the immunoexpression of cyclooxygenase (COX-2, matrix metalloproteinase (MMP-2, transforming growth factor (TGF-β, MIF, Smad 2/3, Smad 2/3 phosphorylated and NFκB p65 in the jugal mucosa. Finally, DEX (1 mg/kg increased interleukin-1 receptor-associated kinase 3 (IRAK-M, glucocorticoid-induced leucine zipper (GILZ, and mitogen-activated protein kinase (MKP1 gene expression and reduced NFκB p65 and serine threonine kinase (AKt gene expression, relative to the 5-FU group. Thus, DEX improved OM induced by 5-FU in hamsters.

  19. Protective effect of dexamethasone on 5-FU-induced oral mucositis in hamsters.

    Science.gov (United States)

    Ribeiro, Susana Barbosa; de Araújo, Aurigena Antunes; Araújo Júnior, Raimundo Fernandes de; Brito, Gerly Anne de Castro; Leitão, Renata Carvalho; Barbosa, Maisie Mitchele; Garcia, Vinicius Barreto; Medeiros, Aldo Cunha; Medeiros, Caroline Addison Carvalho Xavier de

    2017-01-01

    Oral mucositis (OM) is an important side effect of cancer treatment, characterized by ulcerative lesions in the mucosa of patients undergoing radiotherapy or chemotherapy, which has marked effects on patient quality of life and cancer therapy continuity. Considering that few protocols have demonstrated efficacy in preventing this side effect, the aim of this study was to examine the effect of dexamethasone (DEX) on OM induced by 5-fluorouracil (5-FU) in hamsters by studying signaling pathways. OM was induced in hamsters by 5-FU followed by mechanical trauma (MT) on day 4. On day 10, the animals were euthanized. The experimental groups included saline, MT, 5-FU, and DEX (0.25, 0.5, or 1 mg/kg). Macroscopic, histopathological, and immunohistochemical analyses as well as immunofluorescence experiments were performed on the oral mucosa of the animals. The oral mucosal samples were analyzed by enzyme-linked immunosorbent assays, and quantitative real-time polymerase chain reaction (qPCR). DEX (0.5 or 1 mg/kg) reduced inflammation and ulceration of the oral mucosa of hamsters. In addition, DEX (1 mg/kg) reduced the cytokine levels of tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and macrophage migration inhibitory factor (MIF). DEX (1 mg/kg) also reduced the immunoexpression of cyclooxygenase (COX)-2, matrix metalloproteinase (MMP)-2, transforming growth factor (TGF)-β, MIF, Smad 2/3, Smad 2/3 phosphorylated and NFκB p65 in the jugal mucosa. Finally, DEX (1 mg/kg) increased interleukin-1 receptor-associated kinase 3 (IRAK-M), glucocorticoid-induced leucine zipper (GILZ), and mitogen-activated protein kinase (MKP1) gene expression and reduced NFκB p65 and serine threonine kinase (AKt) gene expression, relative to the 5-FU group. Thus, DEX improved OM induced by 5-FU in hamsters.

  20. Long-Wavelength Excesses of FU Orionis Objects: Flared Outer Disks or Infalling Envelopes?

    Science.gov (United States)

    Zhu, Zhaohuan; Hartmann, Lee; Calvet, Nuria; Hernandez, Jesus; Tannirkulam, Ajay-Kumar; D'Alessio, Paola

    2008-09-01

    The mid- to far-infrared emission of the outbursting FU Orionis objects has been attributed either to a flared outer disk or to an infalling envelope. We revisit this issue using detailed radiative transfer calculations to model the recent, high signal-to-noise ratio data from the IRS instrument on the Spitzer Space Telescope. In the case of FU Ori, we find that a physically plausible flared disk irradiated by the central accretion disk matches the observations. Building on our previous work, our accretion disk model with outer disk irradiation by the inner disk reproduces the spectral energy distribution between ~4000 Å and ~40 μm. Our model is consistent with near-infrared interferometry, but there are some inconsistencies with mid-infrared interferometric results. Including the outer disk allows us to refine our estimate of the outer radius of the outbursting, high mass accretion rate disk in FU Ori as ~0.5 AU, which is a crucial parameter in assessing theories of the FU Orionis phenomenon. We are able to place an upper limit on the mass infall rate of any remnant envelope infall rate to ~7 × 10-7 M⊙ yr -1 assuming a centrifugal radius of 200 AU. The FUor BBW 76 is also well modeled by a 0.6 AU inner disk and a flared outer disk. However, V1515 Cyg requires an envelope with an outflow cavity to adequately reproduce the IRS spectrum. In contrast with the suggestion by Green et al., we do not require a flattened envelope to match the observations; the inferred cavity shape is qualitatively consistent with typical protostellar envelopes. This variety of dusty structures suggests that the FU Orionis phase can be present at either early or late stages of protostellar evolution.

  1. Prof. Dr. Rer. Nat. Burkhard Rauhut - Rector of RWTH Aachen University - Germany sign the golden book of the CERN. Greeting from Mr Sigurd Lettow, CERN Chief Financial Officer and Prof. Carlo Rubbia (ex CERN Director-General).

    CERN Multimedia

    Maximilien Brice

    2007-01-01

    Prof. Dr. Rer. Nat. Burkhard Rauhut - Rector of RWTH Aachen University - Germany sign the golden book of the CERN. Greeting from Mr Sigurd Lettow, CERN Chief Financial Officer and Prof. Carlo Rubbia (ex CERN Director-General).

  2. Prof. M. G. K. Menon | History | About IASc | Indian Academy of ...

    Indian Academy of Sciences (India)

    Prof. M. G. K. Menon. President from 1974 to 1976. Prof. M. G. K. Menon. Name: MENON, Mambillikalathil Govind Kumar Elected 1964; Council Service: 1968-85; President: 1974-76; Vice-President: 1971-73. Member of Parliament, New Delhi Date of birth: 28 August 1928, Mangalore, Karnataka. Edn.: Jaswant College ...

  3. Public Lecture | The long road to the LHC | Prof. Lyn Evans, Dr. Daniel Treille and Prof. Peter Jenni | 9 October

    CERN Multimedia

    2014-01-01

    “The long road to the LHC” by Prof. Lyn Evans, Dr. Daniel Treille and Prof. Peter Jenni. Thursday 9 October, 7.30 p.m. in the Globe of Science and Innovation. Talk in English with simultaneous interpreting into French.  Entrance free. Limited number of seats. Reservation essential: +41 22 767 76 76 or cern.reception@cern.ch   Lyn Evans. Lecture by Lyn Evans Abstract The key to the discovery of the Higgs boson has been the development of particle accelerators at CERN over the years. I will explain how a particle accelerator works and will follow the path from the construction of the Proton Synchrotron in the 1950s to the world’s most powerful colliding beam machine, the Large Hadron Collider. Biography Born in 1945, Lyn Evans has spent his whole career in the field of high energy physics and particle accelerators, participating in all the great projects of CERN. From 1993 he led the team that designed, built and commissioned the LHC. He is currently ...

  4. Speakers at CERN's LEP celebration on 9 October 2000 - L. to r. : M. Philippe Busquin, Commissioner for Research European Union; Prof. Marino Gago, Minister of Science and Technology Portugal; Prof. Dimitar Dimitrov, Minister of Education and Science Bulgaria; M. Lubomir Fogas, Deputy Prime Minister Slovak Republic and Prof. Andrzej Wiszniewski Minister of Science Poland : during the LEP celebration.

    CERN Document Server

    Laurent Guiraud

    2000-01-01

    Speakers at CERN's LEP celebration on 9 October 2000 - L. to r. : M. Philippe Busquin, Commissioner for Research European Union; Prof. Marino Gago, Minister of Science and Technology Portugal; Prof. Dimitar Dimitrov, Minister of Education and Science Bulgaria; M. Lubomir Fogas, Deputy Prime Minister Slovak Republic and Prof. Andrzej Wiszniewski Minister of Science Poland : during the LEP celebration.

  5. Effects of combination therapy with vesnarinone, 5-FU and radiation on growth of human pancreatic cancer xenografts in nude mice

    Energy Technology Data Exchange (ETDEWEB)

    Takamura, Michio; Nio, Yoshinori; Minari, Yoshimitsu; Iguchi, Chikage; Sasaki, Susumu; Hirahara, Noriyuki; Tamura, Katsuhiro [Shimane Medical Univ., Izumo (Japan)

    1999-01-01

    We examined the combination effect of Vesnarinone (AZ, 5 mg/day), 5-FU (40 mg/kg) and radiation (RT, 8 Gy/body) for human pancreatic cancer lines which were subcutaneously xenografted in nude mice. AZ alone did not inhibit their growth, but a combination of AZ, 5-FU and RT showed a significant inhibition. Pathological study demonstrated that the ductal structure became more prominent in the poorly differentiated tumors after Vesnarinone treatment. In conclusion, vesnarinone may be a beneficial agent for the differentiation therapy of pancreatic cancer, especially in combination with 5-FU and/or RT. (author)

  6. [Clinical application of "eight acupoints at the head" by Professor QIN Liang-fu].

    Science.gov (United States)

    Zhao, Hai-Yin; Li, Jing

    2007-10-01

    Professor QIN Liang-fu synthesizes the theories of channels of TCM and the theories of modern medicine, and in recent years, he has summed up academic thought of treating diseases by "eight acupoints at the head", and has applied them to treat cerebral diseases and relative diseases of the nervous system. In the present paper, it is introduced that professor QIN Liang-fu' effective samples in treatment of epilepsy, cervical vertigo by using acupuncture and moxibustion at "eight acupoints at the head" combined with Chinese herbs and in treatment of multiple sclerosis by acupuncture and moxibustion at the "eight acupoints at the head" combined with oral administration and external application of Chinese herbs.

  7. Prof dr FJ van Zyl as mens, kerkman en godsdiensfilosoof

    Directory of Open Access Journals (Sweden)

    P. J. van der Merwe

    1989-01-01

    Full Text Available Prof Dr FJ van Zyl as person, church personality and philosopher of religion Professor Francois Jacobus van Zyl (1913-05-06 - served as Head of the Department of Science of Religion and Missiology, Faculty of Theology (Section: Nederduitsch Hervormde Kerk, University of Pretoria, during the period 1960-1978. This article (written by a former student of his and present Head of the same Department contains a short biography, a discussion of his views on Theology, Science of Religion and Philosophy of Religion, and a bibliography. He is portrayed as a theologian with Barthian convictions, while been influenced by Emil Brunner and to a lesser extent by Hendrik Kraemer also. His primary audience was the Nederduitsch Hervormde Kerk and his theological activities (especially in the period 1960-1983 must be seen in relation to his influential role in same church.

  8. The Akt inhibitor ISC-4 synergizes with cetuximab in 5-FU-resistant colon cancer.

    Directory of Open Access Journals (Sweden)

    Joshua E Allen

    Full Text Available Phenylbutyl isoselenocyanate (ISC-4 is an Akt inhibitor with demonstrated preclinical efficacy against melanoma and colon cancer. In this study, we sought to improve the clinical utility of ISC-4 by identifying a synergistic combination with FDA-approved anti-cancer therapies, a relevant and appropriate disease setting for testing, and biomarkers of response. We tested the activity of ISC-4 and 19 FDA-approved anticancer agents, alone or in combination, against the SW480 and RKO human colon cancer cell lines. A synergistic interaction with cetuximab was identified and validated in a panel of additional colon cancer cell lines, as well as the kinetics of synergy. ISC-4 in combination with cetuximab synergistically reduced the viability of human colon cancer cells with wild-type but not mutant KRAS genes. Further analysis revealed that the combination therapy cooperatively decreased cell cycle progression, increased caspase-dependent apoptosis, and decreased phospho-Akt in responsive tumor cells. The synergism between ISC-4 and cetuximab was retained independently of acquired resistance to 5-FU in human colon cancer cells. The combination demonstrated synergistic anti-tumor effects in vivo without toxicity and in the face of resistance to 5-FU. These results suggest that combining ISC-4 and cetuximab should be explored in patients with 5-FU-resistant colon cancer harboring wild-type KRAS.

  9. I Am the Invincible Sword Goddess: Mediatization of Chinese Gender Ideology through Female Kung-Fu Practitioners in Films

    National Research Council Canada - National Science Library

    Mie Hiramoto; Cherise Shi Ling Teo

    2014-01-01

    .... In this paper, we investigate representations of female kung-fu practitioners (nuxia) in films to discuss how processes of mediation and mediatization depict their femininity, so as to mitigate their appropriation of Chinese martial arts masculinity...

  10. Cell Line Derived 5-FU and Irinotecan Drug-Sensitivity Profiles Evaluated in Adjuvant Colon Cancer Trial Data

    DEFF Research Database (Denmark)

    Buhl, Ida Kappel; Gerster, Sarah; Delorenzi, Mauro

    2016-01-01

    patients enrolled in the PETACC-3 prospective randomized clinical trial. A 5-FU profile developed similarly was assessed by comparing the PETACC-3 cohort with a cohort of 359 stage II colon cancer patients who underwent surgery but received no adjuvant therapy. RESULTS: There was no statistically...... patients who benefitted from the addition of irinotecan to 5-FU, we used gene expression profiles based on cell lines and clinical tumor material. These profiles were applied to expression data obtained from pretreatment formalin fixed paraffin embedded (FFPE) tumor tissue from 636 stage III colon cancer...... to identify colon cancer patients who may benefit from 5-FU, however, any biomarker predicting benefit for adjuvant 5-FU must be rigorously evaluated in independent cohorts. Given differences between the two study cohorts, the present results should be further validated....

  11. GRP78 confers the resistance to 5-FU by activating the c-Src/LSF/TS axis in hepatocellular carcinoma.

    Science.gov (United States)

    Gu, Yan-jiao; Li, Hong-dan; Zhao, Liang; Zhao, Song; He, Wu-bin; Rui, Li; Su, Chang; Zheng, Hua-chuan; Su, Rong-jian

    2015-10-20

    5-FU is a common first-line chemotherapeutic drug for the treatment of hepatocellular carcinoma. However the development of acquired resistance to 5-FU confines its clinical usages. Although this phenomenon has been the subject of intense investigation, the exact mechanism of acquired resistance to 5-FU remains elusive. Here, we report that over-expression of GRP78 contributes to acquired resistance to 5-FU in HCC by up-regulating the c-Src/LSF/TS axis. Moreover, we found that the resistance to 5-FU conferred by GRP78 is mediated by its ATPase domain. The ATPase domain differentially increased the expression of LSF, TS and promoted the phosphorylation of ERK and Akt. We further identified that GRP78 interacts physically with c-Src through its ATPase domain and promotes the phosphorylation of c-Src, which in turn increases the expression of LSF in the nucleus. Together, GRP78 confers the resistance to 5-FU by up-regulating the c-Src/LSF/TS axis via its ATPase domain.

  12. Voordrag vir die toekenning van die graad Doctor Educationis, honoris causa, aan prof. dr. Jan Waterink.

    Directory of Open Access Journals (Sweden)

    J. C. Coetzee

    1955-03-01

    Full Text Available Die Raad en die Senaat het op hul vergaderinge in November 1954 besluit om aan prof. dr. Jan Waterink, gebore 20 Oktober 1890, die graad Doctor Educationis honoris causa toe te ken.

  13. NSA Prof. Ostovar Publishes on Iran's Foreign Policy in the Middle East

    OpenAIRE

    Grant, Catherine

    2016-01-01

    National Security Affairs (NSA) News NSA Prof. Afshon Ostovar has written an article titled “From Tehran to Mosul: Iran and the Middle East's Great Game” for the November issue of Foreign Affairs.

  14. A response to Fu et al.'s "Educational interventions to increase HPV vaccination acceptance".

    Science.gov (United States)

    Shapiro, Gilla K; Joyal-Desmarais, Keven; Perez, Samara; Rosberger, Zeev

    2014-11-12

    This commentary is a response to a systematic review, recently published in Vaccine, which investigates the effectiveness of educational interventions in increasing uptake of the human papillomavirus vaccine. The systematic review by Fu et al. (2014) enhances the field's understanding of human papillomavirus vaccine interventions; however, their review contains a number of conceptual and methodological limitations. This commentary begins by addressing these limitations. We then address the importance of studying human papillomavirus vaccine interventions in diverse populations, and conclude by making recommendations for future research.

  15. Interferometric view of the circumstellar envelopes of northern FU Orionis-type stars

    Science.gov (United States)

    Fehér, O.; Kóspál, Á.; Ábrahám, P.; Hogerheijde, M. R.; Brinch, C.

    2017-11-01

    Context. FU Orionis-type objects are pre-main sequence, low-mass stars with large outbursts in visible light that last for several years or decades. They are thought to represent an evolutionary phase during the life of every young star when accretion from the circumstellar disk is enhanced during recurring time periods. These outbursts are able to rapidly build up the star while affecting the physical conditions inside the circumstellar disk and thus the ongoing or future planet formation. In many models, infall from a circumstellar envelope seems to be necessary to trigger the outbursts. Aims: We characterise the morphology and the physical parameters of the circumstellar material around FU Orionis-type stars using the emission of millimetre-wavelength molecular tracers. The high-spatial-resolution study provides insight into the evolutionary state of the objects, the distribution of parameters in the envelopes and the physical processes forming the environment of these stars. Methods: We observed the J = 1-0 rotational transition of 13CO and C18O towards eight northern FU Orionis-type stars (V1057 Cyg, V1515 Cyg, V2492 Cyg, V2493 Cyg, V1735 Cyg, V733 Cep, RNO 1B and RNO 1C) and determine the spatial and velocity structure of the circumstellar gas on a scale of a few thousand AU. We derive temperatures and envelope masses and discuss the kinematics of the circumstellar material. Results: We detected extended CO emission associated with all our targets. Smaller-scale CO clumps were found to be associated with five objects with radii of 2000-5000 AU and masses of 0.02-0.5 M⊙; these are clearly heated by the central stars. Three of these envelopes are also strongly detected in the 2.7 mm continuum. No central CO clumps were detected around V733 Cep and V710 Cas which can be interpreted as envelopes but there are many other clumps in their environments. Traces of outflow activity were observed towards V1735 Cyg, V733 Cep and V710 Cas. Conclusions: The diversity of

  16. Photometric Study of the FU Orionis Object BBW 76 from the Bamberg Observatory Southern Sky Survey

    Science.gov (United States)

    Borisova, A.; Tsvetkova, K. P.; Tsvetkov, M. K.

    2006-04-01

    The Bamberg Observatory Southern Sky Survey provided 93 photographic plates with the FU Orionis object BBW 76, clearly detectable in the time interval 1963-1976. We perform aperture photometry of BBW 76 from the 2 x 2 degrees area near target star scanned with the Epson Expression 1640 XL flatbed scanner. For each plate a transformation of plate magnitude to the GSC 2.2 magnitudes in B photographic band was found out for selected reference stars, and used for deriving B magnitudes of BBW 76. The analysis of the photometric behaviour of BBW 76 is presented.

  17. Der ökologische Fußabdruck: biologische Mutterkuh- und konventionelle Mastrinderhaltung im Vergleich

    OpenAIRE

    Kratochvil, Dr. Ruth; Dekker, Sanne

    2004-01-01

    Der ökologische Fußabdruck ist ein Werkzeug, um den anthropogenen Naturverbrauch vor dem Hintergrund einer nachhaltigen Entwicklung zu bilanzieren. Im vorliegenden Artikel wurde der ÖFA für Rindfleisch aus ökologischer Mutterkuh- und konventioneller Mastrinderhaltung berechnet. Bedingt durch extensive Grünlandbewirtschaftung, höheren Stallgebäude- und Strohbedarf sowie niedrigere tierische Leistungen ist der ÖFA für Rindfleisch aus Mutterkuhhaltung fünf Mal so hoch wie jener für Rindfleisch a...

  18. Self-Assembling Monomeric Nucleoside Molecular Nanoparticles Loaded with 5-FU Enhancing Therapeutic Efficacy against Oral Cancer.

    Science.gov (United States)

    Zhao, Hang; Feng, Hui; Liu, Dongjuan; Liu, Jiang; Ji, Ning; Chen, Fangman; Luo, Xiaobo; Zhou, Yu; Dan, Hongxia; Zeng, Xin; Li, Jing; Sun, Congkui; Meng, Jinyu; Ju, Xiaojie; Zhou, Min; Yang, Hanshuo; Li, Longjiang; Liang, Xinhua; Chu, Liangyin; Jiang, Lu; He, Yang; Chen, Qianming

    2015-10-27

    Conventional oligonucleotide based drug delivery systems suffer from lengthy synthetic protocols, high cost, and poor chemical or enzymatic stability under certain circumstances. Canonical free individual nucleosides cannot form stable nanostructures in aqueous solution as drug vehicles. Here, we report the development of a monomeric self-assembled nucleoside nanoparticle (SNNP) into an efficient drug delivery system which has currently no parallel in such field. This was achieved using a l-configurational pyrimido[4,5-d]pyrimidine nucleoside building block that can form robust discrete nanoparticles in just one step with water as the sole solvent. Its high biocompatibility and low toxicity was demonstrated in vitro and in vivo. In mouse xenograft model of oral squamous cell carcinoma (OSCC), SNNP loaded with 5-fluoro-uracile (5-FU-SNNP) remarkably retarded the tumor growth compared with free 5-FU, albeit SNNP alone showed no antitumor effect. The stability in blood circulation and the effective concentration of 5-FU in tumor tissue were increased upon the loading with SNNP. TUNEL and immunohistochemistry analyses further indicated that the superior in vivo antitumor efficacy of 5-FU-SNNP compared to free 5-FU was associated with an enhanced degree of inhibition of cell proliferation and stimulation of cell apoptosis. Furthermore, SNNP alleviated the toxic side effects of 5-FU. These findings suggested that when loaded with SNNP, 5-FU has better antitumor efficacy and lower side effects, indicating that SNNP can efficiently act as a readily accessible, robust, biocompatible and low-toxic nanobiomaterial which may find wide therapeutic applications clinically in the future.

  19. Gossypol sensitizes the antitumor activity of 5-FU through down-regulation of thymidylate synthase in human colon carcinoma cells.

    Science.gov (United States)

    Yang, Dan; Qu, Jinglei; Qu, Xiujuan; Cao, Yubo; Xu, Ling; Hou, Kezuo; Feng, Wanyu; Liu, Yunpeng

    2015-09-01

    5-Fluorouracil (5-FU) is the basic chemotherapeutic agent used to treat colon cancer. However, the sensitivity of colon cancer cells to 5-FU is limited. Gossypol is a polyphenolic extract of cottonseeds. The purpose of this study was to investigate the activities and related mechanism of gossypol alone or in combination with 5-FU against human colon carcinoma cells. The IC50 of gossypol or/and 5-FU in vitro was tested by 3-(4,5-dimethyl thiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay, and the drug interaction was analyzed using the CalcuSyn method. Cell apoptosis was determined using presidium iodide staining and flow cytometric analysis. Western blotting was used to determine the expression of proteins. Transient transfection method was used to silence protein. The IC₅₀ at 48 h of gossypol in colon cancer cells was 26.11 ± 1.04 μmol/L in HT-29 cells, 14.11 ± 1.08 μmol/L in HCT116 cells, and 21.83 ± 1.05 μmol/L in RKO cells. When gossypol was combined with 5-FU, a synergistic cytotoxic effect was observed in HT-29 cells, HCT116 cells, and RKO cells compared with treatment with gossypol or 5-FU alone. The Western blotting results indicated that gossypol down-regulated thymidylate synthase (TS) rather than thymidine phosphorylase protein expression. Furthermore, the mTOR/p70S6K1 signaling pathway was inhibited in gossypol-treated colon cancer cells, and consequently, cyclin D1 expression was decreased, suggesting an additional mechanism of the observed antiproliferative synergistic interactions. All the observation was confirmed by silencing TS and inactivating the mTOR/p70S6K1 signaling pathway by rapamycin, both of which increased the chemo-sensitizing efficacy of 5-FU. These findings suggest that gossypol-mediated down-regulation of TS, cyclin D1, and the mTOR/p70S6K1 signaling pathways enhances the anti-tumor effect of 5-FU. Ultimately, our data exposed a new action for gossypol as an enhancer of 5-FU-induced cell growth suppression.

  20. Dosimetric study of photobiomodulation therapy in 5-FU-induced oral mucositis in hamsters

    Science.gov (United States)

    Cotomacio, Claudia Carrara; Campos, Luana; Nesadal de Souza, Douglas; Arana-Chavez, Victor Elias; Simões, Alyne

    2017-01-01

    Oral mucositis (OM) is a debilitating consequence of cancer treatment that could be treated with photobiomodulation therapy (PBMT); however, there is no consensus about its dosimetric parameters for OM healing. The aim of this study was to compare different PBMT protocols on OM treatment, through clinical and histological analysis. Thirty hamsters were used, in an induced model of OM by 5-fluorouracil (5-FU) and superficial scratching, in seven days of follow-up. The animals were divided into five groups: control (C), which received only anesthesia and chemotherapeutic vehicle; chemotherapy (Ch), which received anesthesia, 5-FU, and scratches; laser 1 (L1), the same as Ch group, PBMT 6 J/cm2 and 0.24 J (one point); laser 2 (L2), the same as Ch group, PBMT 25 J/cm2 and 1 J (one point); and laser 3 (L3), the same as Ch group, PBMT 4 points of 0.24 J and 6 J/cm2 each. The laser used has λ=660 nm, 0.04 cm2 of spot area, and 40 mW. The best PBMT protocol to maintain lowest OM levels compared to Ch group was L1, followed by L2 and L3. Our results suggest that the application mode of PBMT and the energy delivered per area could interfere with the OM healing.

  1. The effects of lyophilization on the stability of liposomes containing 5-FU.

    Science.gov (United States)

    Glavas-Dodov, M; Fredro-Kumbaradzi, E; Goracinova, K; Simonoska, M; Calis, S; Trajkovic-Jolevska, S; Hincal, A A

    2005-03-03

    Multilamellar liposomes containing 5-fluorouracil (5-FU) were prepared by modified lipid film hydration method and were lyophilized with or without saccharose as cryoprotectant. The effect of lyophilization on the stability of liposomes was evaluated by comparing the vesicle size, encapsulation efficiency and the drug release rate before and after lyophilization/rehydration. The process of lyophilization, without cryoprotectant, resulted in particle size increase and significant content leakage. By the addition of saccharose, the lipid bilayers become more stable and less permeable to the encapsulated drug, saccharose imparted 5-FU retention of about 80% after lyophilization/rehydration. Freeze-drying did not affect the particle size of liposomes containing saccharose as cryoprotectant. The drug release profiles of rehydrated liposomes followed Higuchi's square root model. Also, the obtained release profiles were all biphasic: a rapid initial drug release phase (burst release of the portion of the drug that leaked out of liposomes during the lyophilization) was followed by a slower, approximately constant drug release phase (zero-order kinetics).

  2. Chemoradiotherapy with low-dose cisplatin and 5-FU for advanced esophageal cancer

    Energy Technology Data Exchange (ETDEWEB)

    Tajima, Masayuki; Ichikawa, Wataru; Takagi, Youko; Uetake, Yasuhiro; Kojima, Kazuyuki; Osanai, Takayuki; Takenaka, Satoru; Nihei, Zenro; Sugihara, Kenichi [Tokyo Medical and Dental Univ. (Japan). School of Medicine

    2000-10-01

    We evaluated the efficacy of chemoradiotherapy (CRT) for advanced esophageal cancer, from the view point of response. The relationship between chemoradiosensitivity and dihydropyrimidine dehydrogenase (DPD), thymidylate synthase (TS), and p53 was investigated immunohistochemically. Thirteen patients with inoperable advanced esophageal cancer were involved in this study. CDDP of 10 mg/m{sup 2}/day and 5-FU of 335 mg/m{sup 2}/day were infused intravenously (day 1-5, day 15-19). Radiation was delivered concomitantly at a total dose of 30 Gy. Expressions of p53, DPD and TS were detected using immunohistology in the biopsy samples taken before CRT from 8 patients. Partial response was observed in 8 cases, no change in 4 cases, and progressive disease in one case. The overall response rate was 62%. The reduction rate was higher in tumors positive for p53 expression than in negative ones. The same was true for DPD and TS. The treatment effect was more precisely predicted by combination of p53, DPD and TS. CRT with low-dose CDDP + 5-FU chemotherapy was effective and combination with p53, DPD and TS might be a predictive marker for CRT in patients with advanced esophageal cancer. (author)

  3. Anticancer effect of bromelain with and without cisplatin or 5-FU on malignant peritoneal mesothelioma cells.

    Science.gov (United States)

    Pillai, Krishna; Ehteda, Anahid; Akhter, Javid; Chua, Terence C; Morris, David L

    2014-02-01

    Malignant peritoneal mesothelioma (MPM) is a rare neoplasm of the peritoneum, causally related to asbestos exposure. Nonspecific symptoms with a late diagnosis results in poor survival (Bromelain (cysteine proteinase) hydrolyses glycosidic bonds. Therefore, we investigated the antitumour effect of bromelain on MUC1-expressing MPM cell lines. MUC1 expressions in cells were assessed using immunofluorescent probes with cells grown on cover slips and western blot analysis on cell lysates. The cell lines were treated with various concentrations of bromelain and after 4 and 72 h, their viability was assessed using standard sulforhodamine assays. The cells were also treated with combinations of bromelain and cytotoxic drugs (cisplatin or 5-FU) and their viability was assessed at 72 h. Finally, with western blotting, the effects of bromelain on cellular survival proteins were investigated. PET cells expressed more MUC1 compared with YOU cells. The cell viability of both PET and YOU cells was adversely affected by bromelain, with PET cells being slightly resistant. The addition of bromelain increased the cytotoxicity of cisplatin significantly in both cell lines. However, 5-FU with bromelain did not show any significant increase in cytotoxicity. Bromelain-induced cell death is by apoptosis and autophagy. Bromelain has the potential of being developed as a therapeutic agent in MPM.

  4. Study of the Outflow and Disk surrounding a Post-Outburst FU-Orionis Star

    Science.gov (United States)

    Mellon, Samuel N.; Perez, L. M.

    2014-01-01

    PP 13 is a fan-shaped cometary nebula located in the constellation of Perseus and embedded in the L1473 dark cloud. At optical wavelengths this region is obscured by the surrounding dark cloud, while at infrared and longer wavelengths two northern objects (PP13Na & PP13Nb) and one southern object (PP13S) are revealed. In the past, the young stellar object inside PP13S, called PP13S*, experienced an FU-Orionis type outburst due to a massive accretion episode and is currently returning to its quiescent state. Studying the FU-Orionis phase is crucial to our understanding of how low mass stars form; it is theorized that all low-mass stars go through this outburst phase while they are forming. I used CARMA 3mm interferometric observations of the PP13 region to study the continuum and molecular line emissions from PP13. With these observations, I determined the source of the previously detected outflow and learned new information about the double star system PP13Na and PP13Nb. Although I was not able to detect the accretion disk in the gas emissions, I plan to use computer modeling to help provide constraints on the properties of PP13S* and its outflow.

  5. [Clinical effects of Fu Fang Ya Tong Ding on gingivitis and pericoronitis].

    Science.gov (United States)

    Wan, Hu-Chun; Zhang, Shuang; Wu, Ni-Ya; Kang, Dong; Hu, Li-Jie; Wang, Li-Zhi; Zhang, Ji-Ying; Xie, Ping

    2008-04-01

    To evaluate the clinical effects of Fu Fang Ya Tong Ding on treatment of gingivitis and pericoronitis. 120 clinical patients with gingivitis or pericoronitis were randomly divided into 3 groups (40 patients in each group). After routine rinse treatment for all patients, patients in the test group were treated with Fu Fang Ya Tong Ding, patients in the positive group were treated with iodine glycerol, while that time patients in the negative group received no treatment anymore. Ten minutes after treatment, visual analogue scale (VAS) was used to record the severity of pain for each patient. 3 days and 7 days later, pain and inflammation degree were also recorded by pain three-degree scoring method and index of gingivitis. The total treatment effects were evaluated under a comprehensive clinical treatment standard. 10 minutes after treatment, 40.0% of patients in the test group had almost no pain, while no obvious reduction of pain was found in the control group. 3 days, 7 days after the treatment, 92.5%, 95.0% of patients in the test group had no pain, and 55.0%, 90.0% of patients in the positive group had no pain. In the negative group, there were 47.5% of patients which pain was still remained in 7 days. 7 days after treatment, gingival index in the test group reduced by 25.0% and 42.8% compared with the positive and negative groups (Ppericoronitis through significantly reducing inflammation and pain.

  6. Translasi Pencak Silat Kedalam Film Animasi (Studi Kasus Film Kung Fu Panda

    Directory of Open Access Journals (Sweden)

    Riyo Ramadhan

    2017-09-01

    Full Text Available Sebagai tradisi yang telah membudaya dari sejak zaman dahulu kala, pencak silat lahir sebagai benteng kekuatan pertahanan diri sekaligus menjadi seni yang memperkaya khazanah kebudayaan bangsa Indonesia. Namun, kuatnya terpaan kebudayaan seni bela diri impor yang masuk (karate, kung fu, tae kwon do, muay thai, capoeira, dll, yang selalu didukung dengan berbagai kemasan media entertainment modern, membuat silat menjadi kalah populer bahkan di mata dan persepsi masyarakat Indonesia sendiri. Hal ini mengakibatkan para generasi muda memandang seni bela diri impor menjadi lebih superior ketimbang pencak silat. Jika hal ini terus berlangsung tanpa ada usaha untuk mengembangkan pencak silat melalui media modern, maka akan sangat sulit untuk mempertahankan dan mengembangkan tradisi ini di masa depan. Tujuan dari makalah ini ialah untuk membuktikan dan menggali potensi animasi sebagai media alternatif yang efektif untuk memvisualisasikan adegan dan cerita bertemakan pencak silat. Adapun studi kasus yang menjadi acuan dalam penelitian ialah film animasi “Kung Fu Panda”. Penelitian ini mengkaji studi kasus dengan menggunakan metode kualitatif deskriptif, lalu dianalisis dengan pendekatan analisis deskriptif untuk mengkaji dan mengidentifikasi pemasalahan dan solusi. Pembahasan dari makalah lebih ditekankan pada kekuatan penyampaikan cerita melalui gambar (visual storytelling yang efektif terkait dengan pencak silat. Hasil dari penelitian ialah cara penyampaian pesan yang efektif mengenai elemen dan esensi pencak silat sebagai bentuk translasinya kedalam film animasi. Pesan tersebut dapat disampaikan dengan menggunakan aspek narasi, gesture, dan simbol yang diakomodasi dengan aspek visual storytelling. Translating Pencak Silat Into An Animation Film (Case Study The Film Kung Fu Panda Abstract. A tradition that has been part of Indonesian culture since ancient times, pencak silat was born as a form of self-defense and at the same time has grown into an

  7. [Preparation of ethosomes encapsulated with 5-fluorouracil and the effect of local administered 5-FU ethosome on laryngotracheal stenosis of rabbit].

    Science.gov (United States)

    Yang, Xizhi; Ao, Huafei; Cheng, Xuefeng; Gu, Jian; Kong, Deqiu; Mao, Xiaohui

    2012-10-01

    To evaluate the efficacy of Ethosomes encapsulated with 5-FU in treatment of laryngotracheal stenosis in rabbit models. The 5-FU ethosome was prepared by the thin film hydration method, and the size distribution and the encapsulation efficiency was investigated. The tracheal mucosa was scraped about 0.5 cm in width with a nylon brush to induce the scar formation in the airway,then animals were divided into three groups: 5-FU ethosome group,5-FU group and saline group. Drugs were injected into scar by paracentesis under endoscope in each group respectively. The severity of stenosis was observed under laryngofiberoscope immediately, 7, 14, 21 days after administration. Airway stenosis of 5-FU ethosome group was not significantly different compared with 5-FU group at 7 days after administration, but 5-FU ethosome significantly reduced the airway stenosis at 21 days after administration when compared with 5-FU group and no restenosis was noticed during the observation period. Ethosomes encapsulated with 5-FU was effective for laryngotracheal stenosis. It is a potentially new method for ameliorating airway stenosis originated from granulation tissue.

  8. [Application of ″Fu Yang and activating blood circulation″ in treatment of unstable angina pectoris patients].

    Science.gov (United States)

    Gao, Jia-Liang; Li, Jun; Wang, Jie

    2016-02-01

    Coronary heart disease(CHD) has become a major public health problem in the world, while the unstable angina (UA) is one of an important type. Hypofunction of yang qi in chest and cardiac blood stasis has been considered as the basic pathogenesis of UA.According to the deficiency of yang and blood stasis run through the process of CHD, fu yang and activating blood circulation could be main treatment. Wenxin decoction which has the function of fu yang and activating blood circulation, not only can effectively improve the symptoms of angina pectoris, the ischemic ECG, but also can significantly improve blood rheology, blood lipids and so on. So deepening the theory of ″fu yang and activating blood circulation″ and the application of ″Wenxin decoction″ in the treatment of UA would have an important clinical value for improving the therapeutic efficacy of CHD. Copyright© by the Chinese Pharmaceutical Association.

  9. Chemoresistance to 5-FU inhibited by 635 nm LED irradiation in CD133+ KB cell line.

    Science.gov (United States)

    Kim, Donghwi; Park, Mineon; Jang, Hyunwoong; Hyun, Hoon; Lim, Wonbong

    2018-01-01

    Consistent with cancer stem cell theory, a small fraction of cancer cells, described as cancer stem cells (CSCs), may promote tumor recurrence and anti-cancer drug resistance. Therefore, much effort has been devoted to the development of CSC targeted therapy to vanquish drug resistance. In this study, we have investigated the effect of multiple light-emitting diode (LED) irradiation treatments with conventional anti-cancer drugs on CSC-like oral cancer cells that acquired stemness by ectopic over expression of CD133. To evaluate combined LED irradiation anti-cancer drug effects, we investigated the chemosensitizing effect of 635 nm irradiation on 5-fluorouracil (5FU)-treated KBCD133+ and KBVec cells, interrogating the underlying molecular mechanisms associated with stemness and apoptosis that are responsible for chemopreventive activity. In addition, combination therapy with LED irradiation and 5-FU treatment was carried out in KBCD133+ and KBVec cell-inoculated mouse models. LED irradiation of 635 nm inhibited CSC-like properties consistent with a decrease in OCT4 and NANOG protein expression, reducing colony-forming ability. In addition, LED irradiation enhanced 5-FU-induced cytotoxicity and improved 5-FU chemosensitivity in KBCD133+ via enhancement of apoptosis. These findings were validated in vivo, wherein LED irradiation combined with 5-FU treatment inhibited tumor growth in KBCD133+-inoculated mice. Collectively, our results provide novel evidence for 635 nm irradiation-induced 5-FU chemosensitization of CSC in oral cancer. In addition, this research highlights that 635 nm LED irradiation may serve as an adjunct treatment to conventional chemotherapeutic drugs in patients with oral cancer.

  10. Prof. Hugo de Souza Lopes and the modern system of Sarcophagidae (Diptera

    Directory of Open Access Journals (Sweden)

    Yurij G. Verves

    1989-01-01

    Full Text Available Prof. Dr. Hugo de Souza Lopes is one of the authors of the phylogenetic classification of Sarcophagidae, especially Sarcophaginae. In this paper I present the taxonomic key of the tribes of Sarcophaginae according to his opinion; a list of the 48 genera and subgenera and the 356 species described by Prof. Lopes; and a review of subtribal construction of tribe Sarcophagini with a key of the subtribes. One new subtribe Boettcheriiscina Verves, subtr. nov. and two new monotypic genera (Mufindia Verves, gen. nov., and Sabiella Verves, gen. nov. are described. The role of Prof. Lopes in the knowledge of taxonomy and ecology of American, Oriental, Australian and Oceanic Sarcophagidae is illumined.

  11. TrAnsFuSE refines the search for protein function: oxidoreductases.

    Science.gov (United States)

    Harel, Arye; Falkowski, Paul; Bromberg, Yana

    2012-07-01

    Non-equilibrium catalysis of electron transfer reactions (i.e. redox) regulates the flux of key elements found in biological macromolecules. The enzymes responsible, oxidoreductases, contain specific transition metals in poorly sequence-conserved domains. These domains evolved ∼2.4 billion years ago in microbes and spread across the tree of life. We lack understanding of how oxidoreductases evolved; divergence of sequences makes identification difficult. We developed a method to recognise the various versions of these enzyme-domains in unannotated sequence-space. Often, homology is used to transfer function annotations from experimentally resolved domains to unannotated sequences. Unreliability of inferring homology below 30% sequence identity limits single-sequence based searches. Misaligned functional sites may compromise annotation transfer from even very similar sequences. Combining profile-based searches with knowledge of functional sites could improve domain detection accuracy. Here we present an approach that enhances the search for redox domains using catalytic site annotations. From the scientific literature, we validated annotations of 104 InterPro domains indicated as using "transition metals in redox reactions." These domains mediate electron transfer in 20% of oxidoreductases, primarily employing iron, copper and molybdenum. We used the experimentally identified catalytic residues in these domains to validate sequence alignment-based protein function annotations. Our method, TrAnsFuSE, is 11% and 14% more accurate than PSI-BLAST and InterPro, respectively. Moreover, it is robust for use with other functional residues-we attain higher accuracy at comparable coverage using metal binding, in addition to catalytic, sites. TrAnsFuSE can be used to focus the study of the vast amounts of unannotated sequencing data from meta-/genome projects.

  12. [Post-stroke constipation treated with acupuncture therapy of regulating qi circulation of fu-organ].

    Science.gov (United States)

    Ren, Zhen; Wu, Qing-Ming; Li, Dan-Dan; Liu, Wei-Ai; Li, Xiang-Rong; Lin, Xu-Ming

    2013-10-01

    To compare the difference in the efficacy on post-stroke constipation between acupuncture therapy of regulating qi circulation of fe-organ and Shengxue Tongbian Capsules. Seventy-five patients of post-stroke constipation were randomized into an acupuncture group (39 cases) and a Chinese medicine group (36 cases). The unit mode comprehensive therapy of stroke was adopted as basic treatment in the two groups. In the acupuncture group, acupuncture therapy of regulating qi circulation of fu-organ was added at Tianshu (ST 25), Zhigou (TE 6), Qihai (CV 6) and Zusanli (ST 36), once every day. In the Chinese medicine group, Shengrue Tongbian Capsules were supplemented for oral administration, once every day, 10 g each time. The clinical symptom score of constipation was observed before treatment, after 1 and 2 weeks treatment in the two groups, respectively. The efficacy in 1 week and 2 weeks of treatment and the adverse reaction were observed. In 1 and 2 weeks of treatment, the clinical symptom score of constipation was reduced significantly as compared with that before treatment in the two groups (all P acupuncture group were significant than those in the Chinese medicine group in 2 weeks of treatment (8.03 +/- 2.38 vs 9.20 +/- 2.45, P acupuncture group; and there were 1 case of abdominal pain, 3 cases of diarrhea and 2 cases of nausea and vomiting in the Chinese medicine group. Both the acupuncture therapy of regulating qi circulation of fu-organ and Shengxue Tongbian Capsules achieve the significant efficacy on post-stroke constipation. The efficacy of the acupuncture therapy of regulating qi circulation of fe-organ is better and the adverse reaction is less after long-term persistent treatment.

  13. PROF-TRAC D.4.1 Overview and structure of available material

    DEFF Research Database (Denmark)

    Larsen, Olena Kalyanova; Heiselberg, Per Kvols

    This report introduces available educational and training material from the recent IEE projects adapted in the PROF/TRAC repository. An explanation to the categorisation principle of the material in the repository is the key part of this report. The categorisation schema for educational material ...... in the repository is developed using the skills and qualifications structure, developed in WP 2 of PROF/TRAC project. In this way the continuity of the work is well established and the achievements from between the work packages are harmonised....

  14. Fuels planning: science synthesis and integration; environmental consequences fact sheet 12: Water Erosion Prediction Project (WEPP) Fuel Management (FuMe) tool

    Science.gov (United States)

    William Elliot; David Hall

    2005-01-01

    The Water Erosion Prediction Project (WEPP) Fuel Management (FuMe) tool was developed to estimate sediment generated by fuel management activities. WEPP FuMe estimates sediment generated for 12 fuel-related conditions from a single input. This fact sheet identifies the intended users and uses, required inputs, what the model does, and tells the user how to obtain the...

  15. The Effect of 5 FU on the Expression of Transforming Growth Factor Beta-1 (Tgf-1 in Cultured Tendon Cells

    Directory of Open Access Journals (Sweden)

    Zeynep Karacor Altuntas

    2014-10-01

    Full Text Available This study investigated the effect of the treatment with 1 min exposures to 5-fluorouracil (5-FU  on the expression of TGF-beta 1 in cultured tendon cells. Fibroblasts cultured from the flexor tendons of dog paws were treated with 3 different doses of 5-FU ( control, 5-15-25 mgr /ml for 1 minute.  After 5-FU exposure  the expression of TGF –beta 1 were tested by real time Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR at 3rd and 7th days. There were no statistically significant differences in the expression levels of the TGF-b1 gene between the control group and all other groups on day 3 and 7 (p>0.05.However, when the percentage changes in the TGF-BETA1 gene expression on days 3–7 were compared, there were statistically significant differences and this was maximally observed with 89% +12 (p<0.05 in the group treated with 25-mg/ml 5-FU.  We conclude that 1min. 5-FU application may be  sufficient to prevent adhesions in tendon healing by limiting the expression of TGF-BETA1. 

  16. TS Gene Polymorphisms Are Not Good Markers of Response to 5-FU Therapy in Stage III Colon Cancer Patients

    Directory of Open Access Journals (Sweden)

    A. Fariña-Sarasqueta

    2010-01-01

    Full Text Available Aim: Although the predictive and prognostic value of thymidylate synthase (TS expression and gene polymorphism in colon cancer has been widely studied, the results are inconclusive probably because of methodological differences. With this study, we aimed to elucidate the role of TS gene polymorphisms genotyping in therapy response in stage III colon carcinoma patients treated with 5-FU adjuvant chemotherapy.

  17. Deeply embedded objects and shocked molecular hydrogen : The environment of the FU Orionis stars RNO 1B/1C

    NARCIS (Netherlands)

    Quanz, S. P.; Henning, Th.; Bouwman, J.; Linz, H.; Lahuis, F.

    2007-01-01

    We present Spitzer IRAC and IRS observations of the dark cloud L1287. The mid-infrared ( MIR) IRAC images show deeply embedded infrared sources in the vicinity of the FU Orionis objects RNO 1B and RNO 1C, suggesting their association with a small young stellar cluster. We resolve for the first time

  18. Low Impact Development Intensive Rural Construction Planning in Xu Fu Village Ningbo, China: Planning Review through Rural Resilience Perspective

    Directory of Open Access Journals (Sweden)

    Roosmayri Lovina Hermaputi

    2017-08-01

    Full Text Available Xu Fu Village Ningbo LID Intensive Rural Construction Planning is a cooperation project between Zhejiang University and Ningbo Institute of Technology which named "12th Five-Year National Science and Technology support program-the comprehensive demonstration of the key technology of the beautiful rural construction in the rapid urbanization area of the Yangtze River Delta". This plan focuses on intensive rural construction as part of rural development and construction project that applies the principles of low impact development. Xu Fu Village located in the Yangtze River Delta Region. Currently, the rural growth brings the high impact of development, as a result of rapid urbanization growth arising several issues, such as low land use efficiency, dispersed rural residence, homestead occupies more, rural roads covering over, etc. Meanwhile, Xu Fu village wishes to develop its tourism potential. Thus, the intensive rural construction should be done to avoid the severe effect. The project result hopefully can improve the quality and level of rural residential planning, design, and construction; improve their living environment; save construction land and water use; and improve energy efficiency. The aim of this study is to review the Low Impact Development (LID Intensive Rural Construction in Xu Fu Village, Ningbo City through the rural resilience perspective. This paper will describe the project plan first, then review it through rural resilience perspective. This paper will elaborate the rural resilience theory and then review the rural resiliency through two parts; the first part is identifying rural resilience in rural infrastructure development based on the criteria created by Ayyob S. and Yoshiki Y. (2014, about urban resiliency criteria, and then the second part is reviewing Xu Fu Village resilience through Arup Resilience Qualities (2012, considering three rural resilience domain (economy, ecology, and cultural.

  19. A critical discourse analysis of Rev. Fr. Prof. B.A.C. Obiefuna's “Let's ...

    African Journals Online (AJOL)

    On Tuesday, 30th September, 2014, lecturers of the Faculty of Arts, NnamdiAzikiwe University, Awka voted Rev. Fr. Prof. B.A.C. Obiefuna in as the Dean for a two-year tenure. The speech under analysis is his inaugural address in which he enlightens members of the Faculty Board on his dreams and agenda for the Faculty.

  20. PROF. ULRICH GERHARD LAUTS (1787— 1865). In sy studie „De ...

    African Journals Online (AJOL)

    Test

    van de Nederlandsche Zuid-Afrikaansche Spoorweg-Maatschappij." Am sterdam, 1937. Deel I, bis. 19 e.v.. I") Sien o.m. Dr. .... In „Levensberichten der Afgestorven Medeleden van de Maatschappij der. Nederlandsche Letterkunde. Bijlage tot de ...... kamp te steun het prof. Lauts sy „Kaapsche Landverhuizers ' geskryf/"^).

  1. Prof. P. Rama Rao | History | About IASc | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    BSc. Hons. 56, MA 57; Andhra Univ.: MSc. 57; BHU, Varanasi: PhD. 64. Career: IISC, Bengaluru, Dept. of Metallurgy: Sr. Res. Asst 60-62; BHU, Varanasi, Dept. of Metallurgical Engg.: Lecturer 62-67, Reader 67-75, Prof. 75-82; Defence Metallurgical Res. Lab., Hyderabad: Director 82-91; Govt. of India, Dept. of Sc. and Tech.

  2. Prof. C. N. R. Rao | History | About IASc | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    _1991). Name: RAO, Chintamani Nagesa Ramachandra Elected 1965; Council Service: 1971-94; President: 1989-91; Vice-President: 1974-76, 1983-85; Secretary: 1977-82; Editor of Publi-cations 1983-88. Hon. Prof., IISC and Linus Pauling ...

  3. Blessings Amina Akporhonor (P.hD), Prof Doris O. Bozimo ...

    African Journals Online (AJOL)

    PRESERVATION OF RECORDS IN UNIVERSITY LIBRARIES IN THE SOUTH- SOUTH ZONE OF NIGERIA. Blessings Amina Akporhonor (P.hD), Prof Doris O. Bozimo. Page 5 quality storage containers and good handling practices will help extent the life of records. The step available to protect and preserve records will vary ...

  4. Rezension von: Ulf Gebken, Söhnke Vosgerau (Hg.: Fußball ohne Abseits. Ergebnisse und Perspektiven des Projekts ‚Soziale Integration von Mädchen durch Fußball‘. Wiesbaden: Springer VS 2014.

    Directory of Open Access Journals (Sweden)

    Robert Claus

    2014-12-01

    Full Text Available Seit 2006 wurden im Rahmen des vom Deutschen Fußball-Bund durchgeführten Modellprojektes „Soziale Integration von Mädchen durch Fußball“ an über 200 Standorten Schul-AGs in sogenannten Brennpunktbezirken aufgebaut. Im vorliegenden Sammelband beleuchten die Autor/-innen ausführlich die Funktion von Sport für die pädagogische Kompetenzvermittlung. Zudem erbringen sie einen umfassenden Projektbericht und leisten ein Plädoyer für die Modernisierung des Verhältnisses zwischen Schule und Vereinen, Lehrplan und Ehrenamt. Somit stellt das Buch, wie auch das Projekt, einen enorm wichtigen Beitrag zur Geschlechtergerechtigkeit im Sport dar. Gleichzeitig jedoch liest sich eine Reihe an Texten etwas zu sperrig für den Bericht einer Praxisforschung, und Begriffe im Feld der ‚Integration’ bleiben schwammig.

  5. A Reactor Development Scenario for the FuZE Sheared-Flow Stabilized Z-pinch

    Science.gov (United States)

    McLean, Harry S.; Higginson, D. P.; Schmidt, A.; Tummel, K. K.; Shumlak, U.; Nelson, B. A.; Claveau, E. L.; Forbes, E. G.; Golingo, R. P.; Stepanov, A. D.; Weber, T. R.; Zhang, Y.

    2017-10-01

    We present a conceptual design, scaling calculations, and development path for a pulsed fusion reactor based on a flow-stabilized Z-pinch. Experiments performed on the ZaP and ZaP-HD devices have largely demonstrated the basic physics of sheared-flow stabilization at pinch currents up to 100 kA. Initial experiments on the FuZE device, a high-power upgrade of ZaP, have achieved 20 usec of stability at pinch current 100-200 kA and pinch diameter few mm for a pinch length of 50 cm. Scaling calculations based on a quasi-steady-state power balance show that extending stable duration to 100 usec at a pinch current of 1.5 MA and pinch length of 50 cm, results in a reactor plant Q 5. Future performance milestones are proposed for pinch currents of: 300 kA, where Te and Ti are calculated to exceed 1-2 keV; 700 kA, where DT fusion power would be expected to exceed pinch input power; and 1 MA, where fusion energy per pulse exceeds input energy per pulse. This work funded by USDOE ARPA-E and performed under the auspices of Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344. LLNL-ABS-734770.

  6. Multi-Model Grand Ensemble Hydrologic Forecasting in the Fu River Basin Using Bayesian Model Averaging

    Directory of Open Access Journals (Sweden)

    Bo Qu

    2017-01-01

    Full Text Available Statistical post-processing for multi-model grand ensemble (GE hydrologic predictions is necessary, in order to achieve more accurate and reliable probabilistic forecasts. This paper presents a case study which applies Bayesian model averaging (BMA to statistically post-process raw GE runoff forecasts in the Fu River basin in China, at lead times ranging from 6 to 120 h. The raw forecasts were generated by running the Xinanjiang hydrologic model with ensemble forecasts (164 forecast members, using seven different “THORPEX Interactive Grand Global Ensemble” (TIGGE weather centres as forcing inputs. Some measures, such as data transformation and high-dimensional optimization, were included in the experiment after considering the practical water regime and data conditions. The results indicate that the BMA post-processing method is capable of improving the performance of raw GE runoff forecasts, yielding more calibrated and sharp predictive probability density functions (PDFs, over a range of lead times from 24 to 120 h. The analysis of percentile forecasts in two different flood events illustrates the great potential and prospects of BMA GE probabilistic river discharge forecasts, for taking precautions against severe flooding events.

  7. Chondroprotective Effects and Multitarget Mechanisms of Fu Yuan Capsule in a Rat Osteoarthritis Model

    Directory of Open Access Journals (Sweden)

    Li Zeng

    2017-01-01

    Full Text Available Fu Yuan Capsule (FYC has been clinically used for osteoarthritis (OA and its related diseases for many years in China. However, its pharmacological mechanism remains unclear. This study aimed to investigate the potential chondroprotective effects of FYC on articular cartilage. Rat OA model was induced by anterior cruciate ligament transection. A group of rats was treated with FYC for 12 weeks. Joint structure, types I and II collagen, and proteoglycan were evaluated by histological examination. The expression of C-terminal crosslinking telopeptide of type II collagen, hydroxyproline, a disintegrin and metalloproteinase with thrombospondin motifs, matrix metalloproteinase, interleukin-1 beta, nitric oxide, prostaglandin E2, heat-shock protein 70, transforming growth factor-beta, osteoprotegerin, and receptor activator of nuclear factor κB ligand were detected. Treatment with FYC could protect against articular cartilage injury. FYC treatment significantly decreased the extracellular matrix degradation factors and inflammatory mediators. Moreover, articular cartilage protective factors were increased in the FYC group. The current finding suggests that FYC protects articular cartilage in a rat OA model through various ways. Thus, it may be an effective agent for OA treatment.

  8. Jin Fu Kang Oral Liquid Inhibits Lymphatic Endothelial Cells Formation and Migration

    Directory of Open Access Journals (Sweden)

    Hai-Lang He

    2016-01-01

    Full Text Available Lung cancer is the leading cause of cancer-related deaths worldwide. Jin Fu Kang (JFK, an oral liquid prescription of Chinese herbal drugs, has been clinically available for the treatment of non-small cell lung cancer (NSCLC. Lymphangiogenesis is a primary event in the process of cancer development and metastasis, and the formation and migration of lymphatic endothelial cells (LECs play a key role in the lymphangiogenesis. To assess the activity of stromal cell-derived factor-1 (SDF-1 and the coeffect of SDF-1 and vascular endothelial growth factor-C (VEGF-C on the formation and migration of LECs and clarify the inhibitory effects of JFK on the LECs, the LECs were differentiated from CD34+/VEGFR-3+ endothelial progenitor cells (EPCs, and JFK-containing serums were prepared from rats. SDF-1 and VEGF-C both induced the differentiation of CD34+/VEGFR-3+ EPCs towards LECs and enhanced the LECs migration. Couse of SDF-1 and VEGF-C displayed an additive effect on the LECs formation but not on their migration. JFK inhibited the formation and migration of LECs, and the inhibitory effects were most probably via regulation of the SDF-1/CXCR4 and VEGF-C/VEGFR-3 axes. The current finding suggested that JFK might inhibit NSCLC through antilymphangiogenesis and also provided a potential to discover antilymphangiogenesis agents from natural resources.

  9. Die Osteonekrose des Fußes: Eine Übersicht

    Directory of Open Access Journals (Sweden)

    Schenk S

    2007-01-01

    Full Text Available Die Osteonekrose (ON am Fuß ist eine heterogene Gruppe von Krankheitsbildern, die sich deutlich hinsichtlich Klinik, Verlauf, Prädilektionsalter und Prognose unterscheiden. Ebenso sind die Ursachen für diese Erkrankungen vielfältig: Neben idiopathischen finden sich auch posttraumatische und postoperative Formen. Seltene Ursachen sind Kollagenosen, Stoffwechselerkrankungen wie Diabetes mellitus und Kortikoidtherapie. ON finden sich gehäuft nach Nierentransplantationen. Je nach Ursache tritt eine ON gehäuft in typischer Lokalisation auf. Idiopathische Formen findet man am Os naviculare pedis – Morbus Köhler 1 (MK1, an den Metatarsaleköpfchen – Morbus Köhler 2, "Freiberg’s disease" (MK2, an den Sesambeinen und an der Apophyse des Calcaneus. Operationsbedingte Fälle sind gehäuft am Metatarsaleköpfchen 1 nach Versorgung eines Hallux valgus lokalisiert, posttraumatische Nekrosen am Talus. In diesem Artikel werden die idiopathischen Formen hinsichtlich Klinik und Therapie näher beleuchtet. Bezüglich der Therapie gibt es konservative und operative Ansätze. Die wissenschaftlichen Daten zur Behandlung von idiopathischen Nekrosen sind spärlich, die Behandlungsstrategien jedoch einheitlich und allgemein anerkannt.

  10. Effect of viscous additives on the absorption and hepatic disposition of 5-fluorouracil (5-FU) after application to liver surface in rats.

    Science.gov (United States)

    Kodama, Yukinobu; Horishita, Miyuki; Fumoto, Shintaro; Mine, Toyoharu; Miyamoto, Hirotaka; Yoshikawa, Naoki; Hirata, Haruna; Sasaki, Hitoshi; Nakamura, Junzo; Nishida, Koyo

    2012-10-01

    Objectives  The aim was to study the effect of viscous additives on the absorption and hepatic disposition of 5-fluorouracil (5-FU) after application to the liver surface in rats. Methods  5-FU solution with or without viscous additives was applied to the rat liver surface with a cylindrical diffusion cell. Then, blood and the remaining solution in the diffusion cell were collected at selected times, followed by excision of the liver. The excised liver was divided into three sites and assayed for 5-FU content. Key findings  The absorption rate of 5-FU from the liver surface was decreased in the presence of carboxymethylcellulose sodium (CMC-Na) and polyvinyl alcohol (PVA) as compared with the control. The k(a) values of PVA 15% and CMC-Na 1% were reduced to about 80 and 67% of the control. The maximum plasma concentration of 5-FU was decreased by incorporation of viscous additives. The 5-FU concentration at the diffusion cell attachment site of the liver (site 1) plateaued at 180 min in the absence of viscous additives. On the other hand, the concentration of 5-FU at site 1 increased in a time-dependent manner until 360 min in the presence of viscous additives. Conclusion  Viscous additives might be useful for retaining drugs at their application site and controlling the rate of absorption from the liver surface. © 2012 The Authors. JPP © 2012 Royal Pharmaceutical Society.

  11. Report on visit from Prof. Kim Lutzen: Friday, 6 November 1998, Korolinska Institute (dept of nursing Stockholm, Sweden

    Directory of Open Access Journals (Sweden)

    Kim Lutzen

    1999-01-01

    Full Text Available Prof. Kim Lutzen contacted the Department of Advanced Nursing Sciences, Unisa, via the Department's Web Page. Prof. Lutzen is the Chair of the Department of Nursing, which offers undergraduate, master and doctoral programmes. This Department of Nursing is situated within the Karolinska Institute, which comprises 29 Departments of Health Sciences, including a number of Medical Departments, Dentistry, Occupational Therapy, Physiotherapy, and Nursing. Prof. Lutzen emphasised that there is no Swedish phrase similar to "nursing science", consequently this t e n seems to be somewhat unfamiliar to the Swedish nurses. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

  12. Report on visit from Prof. Kim Lutzen: Friday, 6 November 1998, Korolinska Institute (dept of nursing Stockholm, Sweden

    Directory of Open Access Journals (Sweden)

    Kim Lutzen

    1999-10-01

    Full Text Available Prof. Kim Lutzen contacted the Department of Advanced Nursing Sciences, Unisa, via the Department's Web Page. Prof. Lutzen is the Chair of the Department of Nursing, which offers undergraduate, master and doctoral programmes. This Department of Nursing is situated within the Karolinska Institute, which comprises 29 Departments of Health Sciences, including a number of Medical Departments, Dentistry, Occupational Therapy, Physiotherapy, and Nursing. Prof. Lutzen emphasised that there is no Swedish phrase similar to "nursing science", consequently this t e n seems to be somewhat unfamiliar to the Swedish nurses. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

  13. Extracellular Disposal of Tumor-Suppressor miRs-145 and -34a via Microvesicles and 5-FU Resistance of Human Colon Cancer Cells

    Directory of Open Access Journals (Sweden)

    Yukihiro Akao

    2014-01-01

    Full Text Available The dysregulation of microRNA (miRNA expression causes various kinds of diseases. Especially, alterations in miRNA expression levels are frequently observed in human tumor cells and are associated with cancer pathogenesis. Earlier we established Fluorouracil (5-FU-resistant human colon cancer DLD-1 cells (DLD-1/5FU from parental 5-FU- sensitive DLD-1 cells. In the present study, we examined the expression of miRNA in each cell line and in its extracellular microvesicles (MVs before and after treatment with 5-FU. The nascent RNAs of anti-oncogenic miR-34a and -145 labeled with EU in both cells were proved to be transferred into MVs in both cell lines. The levels of miR-34a and -145 in the cells and in their MVs were not largely different in the two cell lines, and a substantial amount of both miRNAs was secreted by both cell lines even in the steady-state condition. The exposure of both cell lines to 5-FU significantly increased the intracellular levels of miR-145 and miR-34a in the 5-FU-sensitive DLD-1 cells, whereas the level of neither miR was elevated in the DLD-1/5FU cells. Interestingly, the amount of miR-145 detected in the small MVs shed into the medium of the parental cells was reduced after the treatment with 5-FU. On the other hand, the intracellular expression of miR-34a in the DLD-1/5FU cells was down-regulated compared with that in the parental DLD-1 cells even in the steady-state condition. As to the miR-34a secreted into MVs, the increase in the level in DLD-1/5FU cells was greater than that in the parental DLD-1 cells after the treatment with 5-FU. Thus, the intra- and extracellular miR-145 and -34a were closely associated with 5-FU resistance, and the resistance was in part due to the enhanced secretion of miR-145 and -34a via MVs, resulting in low intracellular levels of both miRNAs.

  14. Stevens-Johnson Syndrome Patient Received Combination Chemotherapy Gemcitabine, Cisplatin, and 5-FU for Biliary Tract Cancer.

    Science.gov (United States)

    Aznab, Mozaffar; Khazaei, Mansour

    2016-06-01

    Stevens-Johnson syndrome has been an acute, usually self-limiting disease of the skin and mucous membranes. This case report has presented an evidence of the development Stevens - Johnson syndrome associated with combination chemotherapy administration of 5FU, gemcitabin and cisplatin in a patient with biliary tract cancer. Our case was a 54-year-old woman patient, a case of biliary tract cancer who has developed more severe symptoms of Stevens-Johnson syndrome. Diagnosis has confirmed by skin biopsy of an affected area .The patient has improved with supportive care, and during 25 day occurred recovery. Although Stevens-Johnson syndrome has been a rare toxicity, physicians should pay a special attention to the monitoring of biliary tract cancer patients on combination chemotherapy with 5FU, cisplatin and gemcitabin.

  15. Enteric coated HPMC capsules plugged with 5-FU loaded microsponges: a potential approach for treatment of colon cancer

    Directory of Open Access Journals (Sweden)

    Ankita Gupta

    2015-09-01

    Full Text Available The work was aimed at developing novel enteric coated HPMC capsules (ECHC plugged with 5 Florouracil (5-FU loaded Microsponges in combination with calcium pectinate beads. Modified quasi-emulsion solvent diffusion method was used to formulate microsponges based on 32 factorial design and the effects of independent variables (volume of organic solvent and Eudragit RS100 content on the dependent variables (Particle size, %EE & % CDR were determined. The optimized microsponges (F4 were characterized by SEM, PXRD, TGA and were plugged along with calcium pectinate beads in HPMC capsules and the HPMC capsules were further coated with enteric polymer Eudragit L 100 (Ed-L100 and/ or Eudrgit S 100 (Ed-S 100 in different proportions. In vitro release study of ECHC was performed in various release media sequentially SGF for 2 h, followed by SIF for the next 6 h and then in SCF (in the presence and absence of pectinase enzyme for further 16 h. Drug release was retarded on coating with EdS-100 in comparison to blend of EdS-100: EdL-100 coating. The percentage of 5-FU released at the end of 24 h from ECHC 3 was 97.83 ± 0.12% in the presence of pectinase whereas in control study it was 40.08 ± 0.02% drug. The optimized formulation was subjected to in vivo Roentgenographic studies in New Zealand white rabbits to analyze the in vivo behavior of the developed colon targeted capsules. Pharmacokinetic studies in New Zealand white rabbits were conducted to determine the extent of systemic exposure provided by the developed formulation in comparison to 5-FU aqueous solutions. Thus, enteric coated HPMC capsules plugged with 5-FU loaded microsponges and calcium pectinate beads proved to be promising dosage form for colon targeted drug delivery to treat colorectal cancer.

  16. THE MAN HAD LINGUISTICS LIKED: PROF. DR. DOĞAN AKSAN DİL BİLİMİNİ SEVDİREN ADAM: PROF. DR. DOĞAN AKSAN (1929-2010)

    National Research Council Canada - National Science Library

    Ahmet Turan SİNAN; Sezgin DEMİR

    2010-01-01

    Who is the linguistics studies’ the one of innovators in Turkey, Prof. Dr. Doğan Aksan is very important scientist who fall in love with Turkish, reweal the richness and power of expression of our mother tangue...

  17. Producing High-Performance, Stable, Sheared-Flow Z-Pinches in the FuZE project

    Science.gov (United States)

    Golingo, R. P.; Shumlak, U.,; Nelson, B. A.; Claveau, E. L.; Forbes, E. G.; Stepanov, A. D.; Weber, T. R.; Zhang, Y.; McLean, H. S.; Tummel, K. K.; Higginson, D. P.; Schmidt, A. E.; University of Washington (UW) Collaboration; Lawrence Livermore National Laboratory (LLNL) Collaboration

    2017-10-01

    The Fusion Z-Pinch Experiment (FuZE) has made significant strides towards generating high-performance, stable Z-pinch plasmas with goals of ne = 1018 cm-3 and T =1 keV. The Z-pinch plasmas are stabilized with a sheared axial flow that is driven by a coaxial accelerator. The new FuZE device has been constructed and reproduces the major scientific achievements the ZaP project at the University of Washington; ne = 1016 cm-3,T = 100 eV, r20 μs. These parameters are measured with an array of magnetic field probes, spectroscopy, and fast framing cameras. The plasma parameters are achieved using a small fraction of the maximum energy storage and gas injection capability of the FuZE device. Higher density, ne = 5×1017 cm-3, and temperature, T = 500 eV, Z-pinch plasmas are formed by increasing the pinch current. At the higher voltages and currents, the ionization rates in the accelerator increase. By modifying the neutral gas profile in the accelerator, the plasma flow from the accelerator is maintained, driving the flow shear. Formation and sustainment of the sheared-flow Z-pinch plasma will be discussed. Experimental data demonstrating high performance plasmas in a stable Z-pinches will be shown. This work is supported by an award from US ARPA-E.

  18. Protective Effect of Shen-Fu Injection on Neuronal Mitochondrial Function in a Porcine Model of Prolonged Cardiac Arrest

    Directory of Open Access Journals (Sweden)

    Wei Gu

    2014-01-01

    Full Text Available Background. Shen-Fu injection (SFI following cardiac arrest exhibits neurological effects, but its effect on neurological dysfunction is unclear. This study sought to investigate the protective effect of SFI on nerve cells in a porcine model of cardiac arrest. Methods. After eight minutes of untreated ventricular fibrillation (VF and 2 minutes of basic life support, 24 pigs were randomized and divided into three cardiopulmonary resuscitation groups, which received central venous injection of either Shen-Fu (SFI group; 1.0 ml/kg, epinephrine (EP group; 0.02 mg/kg, or saline (SA group. Surviving pigs were sacrificed at 24 h after ROSC and brains were removed for analysis for morphologic changes of mitochondria by electron microscopy, for mitochondrial transmembrane potential (MTP by flow cytometry, and for opening of the mitochondrial permeability transition pore (MPTP by mitochondrial light scattering. Results. Compared with the EP and SA groups, SFI treatment reduced opening of MPTP, showing higher MMP. In addition, animals treated with SFI showed slight cerebral ultrastructure damage under the electron microscopy. Conclusion. Shen-Fu injection alleviated brain injury, improved neurological ultrastructure, stabilized membrane potential, and inhibited opening of MPTP. Therefore, SFI could significantly attenuate postresuscitation cerebral ischemia and reperfusion injury by modulating mitochondrial dysfunction of nerve cells.

  19. Spectral energy distribution analysis of class I and class II FU Orionis stars

    Energy Technology Data Exchange (ETDEWEB)

    Gramajo, Luciana V.; Gómez, Mercedes [Observatorio Astronómico, Universidad Nacional de Córdoba, Argentina, Laprida 854, 5000 Córdoba (Argentina); Rodón, Javier A., E-mail: luciana@oac.uncor.edu, E-mail: mercedes@oac.uncor.edu, E-mail: jrodon@eso.org [European Southern Observatory, Alonso de Córdova 3107, Vitacura, Casilla 19001, Santiago 19 (Chile)

    2014-06-01

    FU Orionis stars (FUors) are eruptive pre-main sequence objects thought to represent quasi-periodic or recurring stages of enhanced accretion during the low-mass star-forming process. We characterize the sample of known and candidate FUors in a homogeneous and consistent way, deriving stellar and circumstellar parameters for each object. We emphasize the analysis in those parameters that are supposed to vary during the FUor stage. We modeled the spectral energy distributions of 24 of the 26 currently known FUors, using the radiative transfer code of Whitney et al. We compare our models with those obtained by Robitaille et al. for Taurus class II and I sources in quiescence periods by calculating the cumulative distribution of the different parameters. FUors have more massive disks: we find that ∼80% of the disks in FUors are more massive than any Taurus class II and I sources in the sample. Median values for the disk mass accretion rates are ∼10{sup –7} M {sub ☉} yr{sup –1} versus ∼10{sup –5} M {sub ☉} yr{sup –1} for standard young stellar objects (YSOs) and FUors, respectively. While the distributions of envelope mass accretion rates for class I FUors and standard class I objects are similar, FUors, on average, have higher envelope mass accretion rates than standard class II and class I sources. Most FUors (∼70%) have envelope mass accretion rates above 10{sup –7} M {sub ☉} yr{sup –1}. In contrast, 60% of the classical YSO sample has an accretion rate below this value. Our results support the current scenario in which changes experimented by the circumstellar disk explain the observed properties of these stars. However, the increase in the disk mass accretion rate is smaller than theoretically predicted, although in good agreement with previous determinations.

  20. Prof. dr. Darko Radinja (11. 1. 1927–9. 12. 2016

    Directory of Open Access Journals (Sweden)

    Dušan Plut

    2016-12-01

    Full Text Available Brez dvoma je bil prof. dr. Darko Radinja eden tistih univerzitetnih profesorjev, ki se je zaradi izjemnih pedagoških, znanstveno-raziskovalnih dosežkov in občečloveških vrlin neizbrisno zapisal med vodilne, inovativne ustvarjalce snovanja, širjenja in poglabljanja mnogoterih vsebinskih polj slovenske geografije. Za številne slovenske geografinje in geografe pa se je prof. Radinja osebnostno čvrsto zapisal tudi med najbolj odgovorne, tankočutne, a hkrati strokovno, znanstveno zahtevne učitelje in mentorje enciklopedičnega ter celostnega geografskega in interdisciplinarnega horizonta. Celotno njegovo geografsko utirjeno življenjsko pot kodno označuje naravnost pedantna skrb, prizadevanje za jasno in vsebinsko geografsko terminološko, pedagoško in znanstveno neoporečno sporočilno poslanstvo.

  1. The new era of large paraboloid antennas: the life of Prof. Dr. Otto Hachenberg

    OpenAIRE

    R. Wielebinski

    2003-01-01

    Seldom does a scientist get an opportunity in his lifetime to build an instrument that remains unchallenged as the world’s no. 1 for 30 years. The Effelsberg 100- m radio telescope, constructed under the direction of Prof. Dr. Otto Hachenberg, was the world’s largest fully steerable paraboloid antenna since its inauguration in 1971. The radio telescope in a valley in the Eifel mountains near Bonn was constructed with a remarkably precise surface and excellent pointing ...

  2. 11th June 2009-Cyprus-Minister of Education and Culture H. E. Prof. Andreas Demetriou

    CERN Document Server

    Maximilien Brice

    2009-01-01

    Tirage 1 :CERN Director-General, R. Heuer and Minister of Education and Culture, H. E. Prof. Andreas Demetriou; Tirage 2:Council President,T. Åkesson, Ecole Normale Supérieure,K. Kounnas, Chairman of the Cyprus CERN Committee,C. N. Papanicolas, R. Heuer,A. Demetriou, Permanent Representative of the Republic of Cyprus in Geneva,A. Hadjichrysanthou, Directorate Office,E. Tsesmelis

  3. [Study of the immunological mechanism of anti-tumor effects of 5-FU by establishing EL4 tumor-bearing mouse models].

    Science.gov (United States)

    Li, Mo-Lin; Li, Chuan-Gang; Shu, Xiao-Hong; Li, Ming-Xia; Jia, Yu-Jie; Qin, Zhi-Hai

    2007-11-01

    To investigate the immunological mechanism of anti-tumor effect of 5-FU by establishing lymphoma EL4 tumor-bearing mouse models in wild type C57BL/6 mice and nude C57BL/6 mice, respectively. The mouse lymphoma EL4 cells were inoculated subcutaneously into wild type C57BL/6 mice (immune-competent mice). Twelve days later, 5-FU of different doses was administered intraperitoneally to treat these wild type C57BL/6 tumor-bearing mice. The size of tumors in the wild type C57BL/6 mice was observed and recorded to explore the minimal dose of 5-FU that could cure the tumor-bearing mice. Then the same amount of EL4 tumor cells was inoculated subcutaneously into wild type C57BL/6 mice and nude C57BL/6 mice (T cell-deficient mice) simultaneously, which had the same genetic background of C57BL/6. Twelve days later, 5-FU of the minimal dose was given intraperitoneally to treat both the wild type and nude C57BL/6 tumor-bearing mice. The size of tumors in the two different types of mice was observed and recorded. A single dose of 5-FU (75 mg/kg) cured both the EL4 tumor-bearing wild type C57BL/6 mice and the EL4 tumor-bearing nude C57BL/6 mice in the first week. Two weeks after 5-FU treatment, all of the nude mice died of tumor relapse while most of the wild type C57BL/6 mice were fully recovered. A single dose of 5-FU has marked anti-tumor effects on lymphoma EL4 tumor-bearing C57BL/6 mice with or without T lymphocytes. The relapse of tumors after 5-FU treatment might be related to the function of T lymphocytes.

  4. Pharmacoeconomic analysis of adjuvant oral capecitabine vs intravenous 5-FU/LV in Dukes' C colon cancer: the X-ACT trial

    Science.gov (United States)

    Cassidy, J; Douillard, J-Y; Twelves, C; McKendrick, J J; Scheithauer, W; Bustová, I; Johnston, P G; Lesniewski-Kmak, K; Jelic, S; Fountzilas, G; Coxon, F; Díaz-Rubio, E; Maughan, T S; Malzyner, A; Bertetto, O; Beham, A; Figer, A; Dufour, P; Patel, K K; Cowell, W; Garrison, L P

    2006-01-01

    Oral capecitabine (Xeloda®) is an effective drug with favourable safety in adjuvant and metastatic colorectal cancer. Oxaliplatin-based therapy is becoming standard for Dukes' C colon cancer in patients suitable for combination therapy, but is not yet approved by the UK National Institute for Health and Clinical Excellence (NICE) in the adjuvant setting. Adjuvant capecitabine is at least as effective as 5-fluorouracil/leucovorin (5-FU/LV), with significant superiority in relapse-free survival and a trend towards improved disease-free and overall survival. We assessed the cost-effectiveness of adjuvant capecitabine from payer (UK National Health Service (NHS)) and societal perspectives. We used clinical trial data and published sources to estimate incremental direct and societal costs and gains in quality-adjusted life months (QALMs). Acquisition costs were higher for capecitabine than 5-FU/LV, but higher 5-FU/LV administration costs resulted in 57% lower chemotherapy costs for capecitabine. Capecitabine vs 5-FU/LV-associated adverse events required fewer medications and hospitalisations (cost savings £3653). Societal costs, including patient travel/time costs, were reduced by >75% with capecitabine vs 5-FU/LV (cost savings £1318), with lifetime gain in QALMs of 9 months. Medical resource utilisation is significantly decreased with capecitabine vs 5-FU/LV, with cost savings to the NHS and society. Capecitabine is also projected to increase life expectancy vs 5-FU/LV. Cost savings and better outcomes make capecitabine a preferred adjuvant therapy for Dukes' C colon cancer. This pharmacoeconomic analysis strongly supports replacing 5-FU/LV with capecitabine in the adjuvant treatment of colon cancer in the UK. PMID:16622438

  5. lncRNA HOTAIR Contributes to 5FU Resistance through Suppressing miR-218 and Activating NF-κB/TS Signaling in Colorectal Cancer

    Directory of Open Access Journals (Sweden)

    Peilong Li

    2017-09-01

    Full Text Available One major reason for the failure of advanced colorectal cancer (CRC treatment is the occurrence of chemoresistance to fluoropyrimidine (FU-based chemotherapy. Long non-coding RNA HOTAIR has been considered as a pro-oncogene in multiple cancers. However, the precise functional mechanism of HOTAIR in chemoresistance is not well known. In this study, we investigated the biological and clinical role of HOTAIR in 5FU resistance in CRC. Our results showed that HOTAIR negatively regulated miR-218 expression in CRC through an EZH2-targeting miR-218-2 promoter regulatory axis. HOTAIR knockdown dramatically inhibited cell viability and induced G1-phase arrest by promoting miR-218 expression. VOPP1 was shown to be a functional target of miR-218, and the main downstream signaling, NF-κB, was inactivated by HOTAIR through the suppression of miR-218 expression. Additionally, HOTAIR knockdown partially reversed 5FU resistance through promoting miR-218 and inactivating NF-κB signaling. Furthermore, HOTAIR restrained 5FU-induced cytotoxicity on CRC cells through promotion of thymidylate synthase expression. More importantly, high HOTAIR expression was associated with poor response to 5FU treatment. In conclusion, we demonstrated that HOTAIR contributes to 5FU resistance through suppressing miR-218 and activating NF-κB signaling in CRC. Thus, HOTAIR may serve as a promising therapeutic target for CRC patients.

  6. Maps of Relocation and Poems of Tang Dynasty Poets: Li Bai, Du Fu, and Han Yu

    Directory of Open Access Journals (Sweden)

    羅鳳珠、白璧玲、廖泫銘、范毅軍 、鄭錦全 Feng-Ju Lo,Pi-Ling Pai,Hsiung-Ming Liao,I-Chun Fan,Chin-Chuan Cheng

    2014-04-01

    Full Text Available Geographic environments affect literary contents and genre and thus, since ancient times, geographical area has been used to classify Chinese literature. In 1936 Liang Qichao was keenly aware of the relationship between literature and geography and brought up the idea of “literarygeography”. In 1979 Professor Chen Zhengxiang produced maps of birthplaces of Tang and Song poets to show the shift of Chinese cultural center from north to south. Furthermore, in the pastdecade, the attention to research in literary geography and geographical distribution of writersgradually increased. However, most studies focused on geographical distribution of birthplaces of writers and very few focused on the relationship between poets’ journey and the contents of their writings and their geographic environment. Meanwhile, geographic information system and aerialphotography have developed quickly and have become useful tools for the study of literary geography.Since then, the academic circles in Taiwan have built a solid foundation in this area. While Li Baiand Du Fu were called poetic immortal and poetic sage of the middle and end periods of the heydayof Tang Dynasty, respectively, Han Yu advocated the classical Chinese movement and becameone of the eight great authors of Tang and Song dynasties. Han Yu was also the best representative of Middle Tang poets. While the styles of these three poets differed from each other, they held key positions in the development and evolution of Tang poetry. Their footprints spread all over the countryand greatly affected later developments and contemporary of poetry. This project makes use of the digital Tang Dynasty maps by Tan Qixiang, Tang Dynasty transportation route maps by Yan Gengwang,aerial maps, the All Tang Poems, and chronicles of the poets to build the three poets’ relocation maps and study their poetic literature, language, geography, and interactions with others, in hopesof opening a new research direction

  7. The compound Chinese medicine "Kang Fu Ling" protects against high power microwave-induced myocardial injury.

    Directory of Open Access Journals (Sweden)

    Xueyan Zhang

    Full Text Available BACKGROUND: The prevention and treatment of Microwave-caused cardiovascular injury remains elusive. This study investigated the cardiovascular protective effects of compound Chinese medicine "Kang Fu Ling" (KFL against high power microwave (HPM-induced myocardial injury and the role of the mitochondrial permeability transition pore (mPTP opening in KFL protection. METHODS: Male Wistar rats (100 were divided into 5 equal groups: no treatment, radiation only, or radiation followed by treatment with KFL at 0.75, 1.5, or 3 g/kg/day. Electrocardiography was used to Electrophysiological examination. Histological and ultrastructural changes in heart tissue and isolated mitochondria were observed by light microscope and electron microscopy. mPTP opening and mitochondrial membrane potential were detected by confocal laser scanning microscopy and fluorescence analysis. Connexin-43 (Cx-43 and endothelial nitric oxide synthase (eNOS were detected by immunohistochemistry. The expression of voltage-dependent anion channel (VDAC was detected by western blotting. RESULTS: At 7 days after radiation, rats without KFL treatment showed a significantly lower heart rate (P<0.01 than untreated controls and a J point shift. Myocyte swelling and rearrangement were evident. Mitochondria exhibited rupture, and decreased fluorescence intensity, suggesting opening of mPTP and a consequent reduction in mitochondrial membrane potential. After treatment with 1.5 g/kg/day KFL for 7 d, the heart rate increased significantly (P<0.01, and the J point shift was reduced flavorfully (P<0.05 compared to untreated, irradiated rats; myocytes and mitochondria were of normal morphology. The fluorescence intensities of dye-treated mitochondria were also increased, suggesting inhibition of mPTP opening and preservation of the mitochondrial membrane potential. The microwave-induced decrease of Cx-43 and VDAC protein expression was significantly reversed. CONCLUSION: Microwave radiation can

  8. A randomized phase III multicenter trial comparing irinotecan in combination with the Nordic bolus 5-FU and folinic acid schedule or the bolus/infused de Gramont schedule (Lv5FU2) in patients with metastatic colorectal cancer

    DEFF Research Database (Denmark)

    Glimelius, B; Sørbye, H; Balteskard, L

    2008-01-01

    not differ (4% versus 6%, P = 0.3). Grade 3/4 neutropenia (11% versus 5%, P = 0.01) and grade 2 alopecia (18% versus 9%, P = 0.002) were more common in the FLIRI group. The 60-day mortality was 2.4% versus 2.1%. CONCLUSIONS: Irinotecan with the bolus Nordic schedule (FLIRI) is a convenient treatment with PFS...... and OS comparable to irinotecan with the Lv5FU2 schedule. Neutropenia and alopecia are more prevalent, but both regimens are equally well tolerated....

  9. Even great ideas have limits - examining the Turc-Mezentsev and the Tixeront-Fu water balance formulas

    Science.gov (United States)

    Andréassian, Vazken; de Lavenne, Alban

    2017-04-01

    A variety of models and formulas exist to represent the precipitation-flow transformation. In the recent years, simple formulas describing the long-term hydrological balance have received a lot of interest; the most widely discussed being the Turc-Mezentsev (Turc, 1954; Mezentsev, 1955) and the Tixeront-Fu (Tixeront, 1964; Fu, 1981) formulas. Although we largely share the enthusiasm of our colleagues concerning these two formulas, we would like to examine here their limits concerning an important aspect: their inability to reproduce the observed elasticity of streamflow to precipitation and potential evaporation (Andréassian et al., 2016; Berghuijs & Woods, 2016). We discuss whether this could be due to the fact that they do not account for the seasonality, timing and intensity of precipitation, and propose simple ways to include these factors in the original formulations. References Andréassian, V., L. Coron, J. Lerat, and N. Le Moine. 2016. Climate elasticity of streamflow revisited - an elasticity index based on long-term hydrometeorological records. Hydrology and Earth System Sciences, 20, 4503-4524. Berghuijs, W. R. & Woods, R. A., 2016. Space-time asymmetry undermines water yield assessment. Nat. Commun. 7:11603. Fu, B., 1981. On the calculation of the evaporation from land surface (in Chinese). Atmospherica Sinica, 5: 23-31. Mezentsev, V., 1955. Back to the computation of total evaporation (in Russian). Meteorologia i Gidrologia, 5: 24-26. Tixeront, J., 1964. Prediction of streamflow (in French), IAHS publication n°63: General Assembly of Berkeley. IAHS, Gentbrugge, pp. 118-126. Turc, L., 1954. The water balance of soils: relationship between precipitations, evaporation and flow (in French). Annales Agronomiques, Série A(5): 491-595.

  10. Multiwavelength Observations of V2775 Ori, an Outbursting Protostar in L 1641: Exploring the Edge of the FU Orionis Regime

    Science.gov (United States)

    Fischer, William J.; Megeath, S. Thomas; Tobin, John J.; Stutz, Amelia M.; Ali, Babar; Remming, Ian; Kounkel, Marina; Stanke, Thomas; Osorio, Mayra; Henning, Thomas; Manoj, P.; Wilson, T. L.

    2012-09-01

    Individual outbursting young stars are important laboratories for studying the physics of episodic accretion and the extent to which this phenomenon can explain the luminosity distribution of protostars. We present new and archival data for V2775 Ori (HOPS 223), a protostar in the L 1641 region of the Orion molecular clouds that was discovered by Caratti o Garatti et al. to have recently undergone an order-of-magnitude increase in luminosity. Our near-infrared spectra of the source have strong blueshifted He I λ10830 absorption, strong H2O and CO absorption, and no H I emission, all typical of FU Orionis sources. With data from the Infrared Telescope Facility, the Two Micron All Sky Survey, the Hubble Space Telescope, Spitzer, the Wide-field Infrared Survey Explorer, Herschel, and the Atacama Pathfinder Experiment that span from 1 to 70 μm pre-outburst and from 1 to 870 μm post-outburst, we estimate that the outburst began between 2005 April and 2007 March. We also model the pre- and post-outburst spectral energy distributions of the source, finding it to be in the late stages of accreting its envelope with a disk-to-star accretion rate that increased from ~2 × 10-6 M ⊙ yr-1 to ~10-5 M ⊙ yr-1 during the outburst. The post-outburst luminosity at the epoch of the FU Orionis-like near-IR spectra is 28 L ⊙, making V2775 Ori the least luminous documented FU Orionis outburster with a protostellar envelope. The existence of low-luminosity outbursts supports the notion that a range of episiodic accretion phenomena can partially explain the observed spread in protostellar luminosities.

  11. [Syndrome of inappropriate antidiuretic hormone secretion following adjuvant CDDP and 5-FU administration in a patient with esophageal carcinoma].

    Science.gov (United States)

    Horio, Takuya; Tsujimoto, Hironori; Akase, Takayoshi; Sakamoto, Naoko; Yaguchi, Yoshihisa; Hiraki, Shuuichi; Aiko, Satoshi; Takechi, Hanako; Hase, Kazuo; Maehara, Tadaaki

    2010-10-01

    A case of hyponatremia following the first course of systemic adjuvant chemotherapy with cisplatin (CDDP) and 5-FU in a previously treated patient with esophageal cancer is reported. A 61-year-old man was admitted to our hospital for adjuvant chemotherapy after transthoracic esophagectomy and 3-field lymphadenectomy for esophageal cancer. Six days following chemotherapy, his serum sodium concentration was found to be 118 mEq/L, without edema or dehydration. This hyponatremic state was diagnosed as the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) induced by CDDP, based on the hypo-osmolality of his serum and urine, and an inappropriate level of plasma vasopressin.

  12. Prof C. N. Yang (Physics Nobel Prize 1957) from Tsinghua University (Beijing) during his CERN Colloquium: "Thematic Melodies of Twentieth Century Theoretical Physics: Quantization, Symmetry and Phase Factor".

    CERN Multimedia

    Maximilien Brice

    2006-01-01

    Prof C. N. Yang (Physics Nobel Prize 1957) from Tsinghua University (Beijing) during his CERN Colloquium: "Thematic Melodies of Twentieth Century Theoretical Physics: Quantization, Symmetry and Phase Factor".

  13. A novel comprehensive set of fungal Real time PCR assays (fuPCR) for the detection of fungi in immunocompromised haematological patients-A pilot study.

    Science.gov (United States)

    Rahn, Sebastian; Schuck, Anna; Kondakci, Mustafa; Haas, Rainer; Neuhausen, Nicole; Pfeffer, Klaus; Henrich, Birgit

    2016-12-01

    Fungal infections are recognized in an increasing number of patients with immunological deficits and are associated with high rates of mortality (Brown et al., 2012a). In this pilot-study, a rapid Real time PCR (fuPCR) was designed for the detection and differentiation of fungal pathogens in clinical specimens of haematological patients. The fuPCR, targeting the internal transcribed spacer region 2 (ITS2) of rDNA region, is comprised of seven multiplex reactions, which were shown to be specific and sensitive for a comprehensive spectrum of clinically relevant fungal species. This was validated by testing respective fungal DNAs in each fuPCR reaction and 28 respiratory samples of fungal pneumonia-proven patients. Clinical sample sets of throat swab, EDTA-blood and blood sera from 50 patients with severe haematological malignancies, including haematopoietic stem cell transfer (HSCT), and samples from 30 healthy individuals were then analysed. In a first step, 198 samples of immunosuppressed patients were solely examined by fuPCR; and 50.8% (33/65) respiratory swabs, 4.8% (3/63) EDTA blood samples and 1.4% (1/70) blood serum samples were tested positive. In a second step, 56 respiratory samples of immunosuppressed patients and 30 of healthy individuals were simultaneously analysed by fuPCR and standard cultivation techniques. By both methods 30.4% (17/56) swabs of the immunocompromised patients were tested positive, 37.5% (21/56) were tested negative and 32.1% (18/56) were tested fuPCR positive and culture negative. In analysing the blood samples of the immunocompromised patients 5.4% (3/56) EDTA blood samples and 16.1% (9/56) sera samples were tested fuPCR-positive, whereas all samples of 30 healthy individuals with no signs of immunological deficits were tested negative by fuPCR. 38.9% (14/36) of the fungi detected in respiratory samples of the immunosuppressed patients, belonged to Candida spp., 47.2% (17/36) to Saccharomyces spp., 5.6% (2/36) to Cladosporium spp

  14. Progress on Scaling the Sheared-Flow Stabilized Z-Pinch: The Fusion Z-Pinch Experiment ``FuZE''

    Science.gov (United States)

    Nelson, B. A.; Shumlak, U.; Claveau, E. L.; Forbes, E. G.; Golingo, R. P.; Stepanov, A. D.; Weber, T. R.; Zhang, Y.; McLean, H. S.; Higginson, D. P.; Schmidt, A. E.; Tummel, K. K.

    2017-10-01

    The sheared-flow-stabilized (SFS) Z-pinch ZaP experiment was constructed based on calculations showing stabilization of the kink and sausage instabilities with sufficient flow shear. ZaP experimentally demonstrated production and sustainment of an SFS Z-pinch for a wide range of plasma parameters, with densities up to n = 5 ×1022 m-3 and a pinch radius of a=1 cm. The follow-on ZaP-HD (high density) experiment demonstrated scaling of the SFS Z-pinch to 2-3x smaller radii and 10x higher densities than ZaP, with up to 1 keV temperatures. Based on the successful results of ZaP and ZaP-HD, the Fusion Z-pinch Experiment (FuZE) project is experimentally and computationally studying scaling the plasma performance toward fusion conditions, with the target of a smaller radius, a=1 mm, and higher density, n = 2 ×1024 m-3. Initial FuZE experimental results show several hundred eV ion temperatures, with pinch currents of 100-200 kA and a few mm radius. 2D kinetic calculations show stabilization of instabilities at moderate sheared flows, and 3D kinetic calculations are in progress. This work is supported by an award from US ARPA-E.

  15. Estimation of Asian Dust Aerosol Effect on Cloud Radiation Forcing Using Fu-Liou Radiative Model and CERES Measurements

    Science.gov (United States)

    Su, Jing; Huang, Jianping; Fu, Qiang; Minnis, Patrick; Ge, Jinming; Bi, Jianrong

    2008-01-01

    The impact of Asian dust on cloud radiative forcing during 2003-2006 is studied by using the Earth's Radiant Energy Budget Scanner (CERES) data and the Fu-Liou radiative transfer model. Analysis of satellite data shows that the dust aerosol significantly reduced the cloud cooling effect at TOA. In dust contaminated cloudy regions, the 4-year mean values of the instantaneous shortwave, longwave and net cloud radiative forcing are -138.9, 69.1, and -69.7 Wm(sup -2), which are 57.0, 74.2, and 46.3%, respectively, of the corresponding values in more pristine cloudy regions. The satellite-retrieved cloud properties are significantly different in the dusty regions and can influence the radiative forcing indirectly. The contributions to the cloud radiation forcing by the dust direct, indirect and semi-direct effects are estimated using combined satellite observations and Fu-Liou model simulation. The 4-year mean value of combination of indirect and semi-direct shortwave radiative forcing (SWRF) is 82.2 Wm(sup -2), which is 78.4% of the total dust effect. The direct effect is only 22.7 Wm(sup -2), which is 21.6% of the total effect. Because both first and second indirect effects enhance cloud cooling, the aerosol-induced cloud warming is mainly the result of the semi-direct effect of dust.

  16. [Clinical study of serum and tissue concentrations of FT-207 and 5-FU in patients with cancer of the large intestine following preoperative application of FT-207 suppositories].

    Science.gov (United States)

    Okuda, M; Teramoto, T; Yoshida, H; Sato, K; Ushijima, Y; Uematsu, Y

    1982-09-01

    1.5 g/day of FT-207 suppository was administered for two weeks prior to operation to twenty patients with large bowel carcinoma of familiar poliposis coli. The level of FT-207 and 5-FU in serum, lymph node, tumor and normal colonic mucosa were determined by bioassay. The levels of FT-207 in the rectum, sigmoid colon and tumor were higher than that in serum. The levels of 5-FU in the rectum, sigmoid colon, tumor and lymph node were also higher than that in serum. The levels of FT-207 and 5-FU in carcinoma of the rectum was higher than those in serum. Compared with the level in normal rectal mucosa, only the level of 5-FU in rectal carcinoma was higher. From the histological point of view, the highest levels of FT-207 and 5-FU was observed in well-differentiated adenocarcinoma. There was no side effect experienced in our series, therefore, FT-207 suppository seems to be one of the safe promising preoperative chemotherapies.

  17. “Pensiero Critico”: Presentazione del volume in onore del Prof. Michele Borrelli

    Directory of Open Access Journals (Sweden)

    Francesca Caputo

    2012-06-01

    Full Text Available Abstract: “Critical Thought”: Presentation of the volume in honour of Prof. Michele Borrelli (International Centre of Philosophy Karl-Otto Apel - Wednesday, April 4, 2012, 16.00/20.00 - This paper has been presented during the public presentation of the volume “Critical Thought” that collects some international writings in honour of the philosopher and the pedagogist Michele Borrelli. The paper focus on some pillars of the Michele Borrelli’s research activity: the relationship between philosophy and pedagogy; the dialectic subject-society and the pedagogical consequences; theactuality of the critical thought.

  18. In Memoriam: Prof. Dr Jelena Milogradov-Turin (1935-2011)

    Science.gov (United States)

    2011-12-01

    Prof. dr Jelena Milogradov-Turin was born in Belgrade to a family of Russian immigrants on 28 January 1935. She completed her primary and secondary education in Belgrade and after that enrolled at the Faculty of Sciences and Mathematics - Physics Group, from which she graduated in 1959. She obtained her MSc degree in 1972 from the University of Manchester, England, with a thesis entitled "The Survey of the Region 6^{h} thesis "The All Sky Survey at 38 MHz and the Galactic Spectral Index" in the field of astronomical/astrophysical sciences, at the University of Belgrade in 1982.

  19. Ethical and cultural value of the Earth sciences. Interview with Prof. Giulio Giorello

    Directory of Open Access Journals (Sweden)

    Silvia Peppoloni

    2012-07-01

    Full Text Available Prof. Giulio Giorello is amongst the most prominent philosophers of science in Italy and in the world. He is currently Professor of the Philosophy of Science at the University of Milan, Director of the Series ‘Science and Ideas’ (Raffaele Cortina Books Editor, and Literary Journalist of the cultural pages of the Corriere della Sera, one of the most important of the Italian newspapers. In this keynote presentation, in interview form, he talks about the value that the Earth sciences have had through history, framing this group of disciplines in ethical and epistemological terms, and highlighting some important elements that have to be considered in geological activities.

  20. Clinical study of the combination of small amount of nedaplatin (CDGP)/5-FU with radiation for the treatment of esophageal cancer

    Energy Technology Data Exchange (ETDEWEB)

    Inaba, Hiroyuki; Tsuda, Takashi; Miyazaki, Aya [St. Marianna Univ., Kawasaki, Kanagawa (Japan). School of Medicine] (and others)

    2002-10-01

    Recently chemoradiotherapy for esophageal cancer has been drawing public attention to the issue of quality of life maintenance for patients. Although the standard method of chemoradiotherapy is CDDP/5FU, it has been claimed that CDGP (a derivative of CDDP) alone is more effective than CDDP for the treatment of esophageal cancer due to its low nephro- and digestive toxicity. We used a small amount of CDGP/5-FU in combination with radiation instead of CDDP, for the treatment of esophageal cancer and performed clinical examination of patients. The partial response rate was 80% and the complete response rate was 50%. Major side-effects were leukopenia, neutropenia, thrombocytopenia and anemia. Further study of dosage and schedule is necessary, however, CDGP/5-FU combined with radiation therapy could be used as choices of chemoradiotherapy for esophageal cancer in the future. (author)

  1. Análisis y determinación de parámetros físicos de estrellas de tipo FU Orionis

    Science.gov (United States)

    Gramajo, L.; Gómez, M.; Whitney, B.

    FU Orionis stars (FUORs) are pre-main sequence objects that periodically incur in a steeply increase of brightness (outburst) of DeltaV~ 6 mag in a period of ~ 10 yr, followed by a gradual descent to the original magnitude in an interval of time of ~100 yr. In this contribution we present initial results on the modeling of the spectral energy distributions (SEDs) of a group of 7 FU Orionis stars: FU Ori, V1515 Cyg, V1057 Cyg, Z CMa, BBW 76, V1735 Cyg, and V883 Ori. We initially used the grid of SEDs calculated by Robitaille et al. (2006). This solution was refined applying the code developed by Whitney et al. (2003). We derived physical and geometrical parameters for the disks of these FUORs. We compared these properties with those of ''canonical'' T Tauri disks. FULL TEXT IN SPANISH

  2. [Successful treatment of a patient with recurrent ovarian clear cell adenocarcinoma under combination chemotherapy of 5-FU (civ) and low-dose CDDP (i.v.)].

    Science.gov (United States)

    Sakaihara, M; Sakai, K; Hara, Y; Kataoka, S; Tabata, M; Hanatani, K; Hareyama, H

    2000-01-01

    Resistance to conventional chemotherapy including CDDP is the most important therapeutic problem in ovarian cancer. The combination chemotherapy of 5-FU (civ) and low-dose CDDP (i.v.) was applied to a patient with recurrent ovarian clear cell adenocarcinoma (stage IIa), which is often more resistant to systemic chemotherapy than other ovarian adenocarcinomas and is a poor prognostic factor. The patient underwent cytoreductive surgery. Then, 5-FU 375 mg/m2/day civ (days 1-5, 8-12, 15-19, 22-26) and CDDP 3.75 mg/m2/day i.v. (days 1-5, 8-12, 15-19, 22-26) were administered. After four courses of this treatment, there is no sign of recurrence. This result indicates that the combination of 5-FU and CDDP is useful in the treatment of recurrent ovarian cancers.

  3. Adli Toksikolojinin Duayen İsmi Prof Dr Hayri Sözen

    Directory of Open Access Journals (Sweden)

    Sermet Koç

    2011-12-01

    Full Text Available İ. Ü. Cerrahpaşa Tıp Fakültesi kuruluşunun 40. yılında anabilim dallarından kendi tarihçelerini hazırlamalarını istedi. Bu görev anabilim dalımızda ise, bana verildi. Önce tüm adli tıp ve bilimler camiasından özür dilemeliyim, neden? Çünkü üzerinde oturduğum külliyatın tozları kaldırıldığında, altında bir hazine varmış gördüm; biz bakmayı bilmiyormuşuz geç te olsa öğrendim ve çok üzüldüm. Sonra; Prof. Dr. Hayri Sözen'in dosyasını alıp baktığımda, çok heyecanlandım ve çok mutluluk duydum; bir o kadar da hicap duydum. Ben daha önce ne yazık ki hakkında çok az şey biliyordum. Adını önce aynı dönemde adli tıp asistanlığı yaptığımız sevgili Prof. Dr. Şevki Sözen'in babası olduğu için duymuştum. Daha sonra uzmanlık ve doçentlik sınavına hazırlanırken, Prof. Dr. Cahit Özen'le birlikte hazırladıkları ‘‘Adli Tıp ve Toksikoloji” kitabından asıl bilimsel boyutta tanımıştım ve özellikle toksikoloji konularını büyük ölçüde onun yazdığı bölümlerden (toplam 245 sayfa tutan ikinci kısmını çalışmıştım. Şevki Hoca'ya biraz sitem ettim, bu büyük insanla ilgili birkaç cümle olsun bahsetmemişti bize; ama bu onun mütevazı kişiliğinden, övünmeyi sevmemesinden kaynaklanıyordu kuşkusuz. Oysa ne kadar övünse azdır babası ile. Sözü daha fazla uzatmaya gerek yok, siz değerli adli bilimciler benim Prof. Dr. Hayri Sözen'in arşivdeki dosyasından derlediğim ve Prof. Dr. Şevki Sözen'e danışarak düzenlediğim bu kısa biyografiyi okuyarak kararı size bırakıyorum.

  4. Estimation of Asian dust aerosol effect on cloud radiation forcing using Fu-Liou radiative model and CERES measurements

    Directory of Open Access Journals (Sweden)

    Jing Su

    2008-05-01

    Full Text Available The impact of Asian dust on cloud radiative forcing during 2003–2006 is studied by using the Clouds and Earth's Radiant Energy Budget Scanner (CERES data and the Fu-Liou radiative transfer model. Analysis of satellite data shows that the dust aerosol significantly reduced the cloud cooling effect at TOA. In dust contaminated cloudy regions, the 4-year mean values of the instantaneous shortwave, longwave and net cloud radiative forcing are −138.9, 69.1, and −69.7 Wm−2, which are 57.0, 74.2, and 46.3%, respectively, of the corresponding values in pristine cloudy regions. The satellite-retrieved cloud properties are significantly different in the dusty regions and can influence the radiative forcing indirectly. The contributions to the cloud radiation forcing by the dust direct, indirect and semi-direct effects are estimated using combined satellite observations and Fu-Liou model simulation. The 4-year mean value of combination of dust indirect and semi-direct shortwave radiative forcing (SWRF is 82.2 Wm−2, which is 78.4% of the total dust effect. The dust direct effect is only 22.7 Wm−2, which is 21.6% of the total effect. Because both first and second indirect effects enhance cloud cooling, the aerosol-induced cloud warming is mainly the result of the semi-direct effect of dust.

  5. Wheat germ allutinin functionalized crosslinked polyelectrolyte microparticles for local colon delivery of 5-FU: In vitro efficacy and in vivo gastrointestinal distribution

    DEFF Research Database (Denmark)

    Glavas-Dodov, Marija; Steffansen, Bente; Crcarevska, Maja

    2013-01-01

    We have previously reported the development and characterisation of wheat germ agglutinin (WGA)-functionalised chitosan-Ca-alginate (CTS-Ca-ALG) microparticles (MPs) loaded with acid-resistant particles of 5-fluorouracil (5-FU). In the present work, our goal was to evaluate the potential of these...

  6. The new era of large paraboloid antennas: the life of Prof. Dr. Otto Hachenberg

    Science.gov (United States)

    Wielebinski, R.

    2003-05-01

    Seldom does a scientist get an opportunity in his lifetime to build an instrument that remains unchallenged as the world’s no. 1 for 30 years. The Effelsberg 100- m radio telescope, constructed under the direction of Prof. Dr. Otto Hachenberg, was the world’s largest fully steerable paraboloid antenna since its inauguration in 1971. The radio telescope in a valley in the Eifel mountains near Bonn was constructed with a remarkably precise surface and excellent pointing characteristics. Only in 2001 the 100-m × 110-m Green Bank Telescope became operational and marginally surpassed Effelsberg’s performance. The Effelsberg telescope is still fully operational in 2002 and looking forward to an exciting future. It is a memorial to the ingenuity of a person who influenced the development of German radio astronomy.

  7. The new era of large paraboloid antennas: the life of Prof. Dr. Otto Hachenberg

    Directory of Open Access Journals (Sweden)

    R. Wielebinski

    2003-01-01

    Full Text Available Seldom does a scientist get an opportunity in his lifetime to build an instrument that remains unchallenged as the world’s no. 1 for 30 years. The Effelsberg 100- m radio telescope, constructed under the direction of Prof. Dr. Otto Hachenberg, was the world’s largest fully steerable paraboloid antenna since its inauguration in 1971. The radio telescope in a valley in the Eifel mountains near Bonn was constructed with a remarkably precise surface and excellent pointing characteristics. Only in 2001 the 100-m × 110-m Green Bank Telescope became operational and marginally surpassed Effelsberg’s performance. The Effelsberg telescope is still fully operational in 2002 and looking forward to an exciting future. It is a memorial to the ingenuity of a person who influenced the development of German radio astronomy.

  8. Analytical estimation of annual runoff distribution in ungauged seasonally dry basins based on a first order Taylor expansion of the Fu's equation

    Science.gov (United States)

    Caracciolo, D.; Deidda, R.; Viola, F.

    2017-11-01

    The assessment of the mean annual runoff and its interannual variability in a basin is the first and fundamental task for several activities related to water resources management and water quality analysis. The scarcity of observed runoff data is a common problem worldwide so that the runoff estimation in ungauged basins is still an open question. In this context, the main aim of this work is to propose and test a simple tool able to estimate the probability distribution of the annual surface runoff in ungauged river basins in arid and semi-arid areas using a simplified Fu's parameterization of the Budyko's curve at regional scale. Starting from a method recently developed to derive the distribution of annual runoff, under the assumption of negligible inter-annual change in basin water storage, we here generalize the application to any catchment where the parameter of the Fu's curve is known. Specifically, we provide a closed-form expression of the annual runoff distribution as a function of the mean and standard deviation of annual rainfall and potential evapotranspiration, and the Fu's parameter. The proposed method is based on a first order Taylor expansion of the Fu's equation and allows calculating the probability density function of annual runoff in seasonally dry arid and semi-arid geographic context around the world by taking advantage of simple easy-to-find climatic data and the many studies with estimates of the Fu's parameter worldwide. The computational simplicity of the proposed tool makes it a valuable supporting tool in the field of water resources assessment for practitioners, regional agencies and authorities.

  9. E2F1/TS Immunophenotype and Survival of Patients with Colorectal Cancer Treated with 5FU-Based Adjuvant Therapy.

    Science.gov (United States)

    Sulzyc-Bielicka, Violetta; Domagala, Pawel; Bielicki, Dariusz; Safranow, Krzysztof; Rogowski, Wojciech; Domagala, Wenancjusz

    2016-07-01

    The predictive value of thymidylate synthase (TS) expression alone for 5FU-based treatment of colorectal cancer (CRC) has not been clinically confirmed. Little is known on the association of expression of E2F1, which controls the transcription of genes encoding proteins engaged in DNA synthesis including TS, and survival of patients with CRC. The purpose of this study is to assess the correlation between expression of both E2F1 and TS in CRCs and survival of patients administered adjuvant 5FU-based chemotherapy, in order to find a better predictor of treatment outcome than expression of TS or E2F1 alone. Nuclear TS and E2F1 were detected by immunohistochemistry in tissue microarrays from 190 CRCs (Astler-Coller stage B2 or C). Multivariate analysis identified significant association of the combined E2F1+TS+ immunophenotype with worse OS (HR = 3,78, P = 0,009) and DFS (HR = 2,30, P = 0,03) of patients with colon cancer. There were significant differences between E2F1+TS+ and E2F1-TS- Kaplan-Meier survival curves in relation to DFS (P = 0.008) and OS (P = 0.01). About 37 and 31 % difference in 3-year DFS and OS respectively were seen between patients with E2F1+TS+ vs. E2F1-TS- colon cancer immunophenotype. The E2F1+TS+ immunophenotype may be a marker of poor prognosis (the worst DFS and OS) of patients with colon cancer treated with 5FU-based adjuvant therapy. A subgroup of patients with this immunophenotype may require different and perhaps more aggressive treatment than 5FU-based chemotherapy. Thus, the combined E2F1/TS immunophenotype could be a potential indicator of colon cancer sensitivity to 5FU.

  10. 5-FU or mitomycin C hepatic arterial infusion after failure of arterial oxaliplatin in patients with colorectal cancer unresectable liver metastases.

    Science.gov (United States)

    Pernot, Simon; Velut, Guillaume; Kourie, Rapahel Hampig; Amouyal, Gregory; Sapoval, Marc; Pointet, Anne Laure; Landi, Bruno; Zaimi, Yosra; Lepère, Céline; Pellerin, Olivier; Taieb, Julien

    2017-12-07

    Hepatic arterial infusion (HAI) chemotherapy with oxaliplatin is an accepted option in the management of colorectal cancer (CRC) with dominant liver metastases (LM). However, despite prolonged control, some patients experience disease progression. On the other hand, oxaliplatin leads to dose-limiting toxicity. In these cases, the use of a second-line HAI with an alternative drug has never been reported to date. We evaluated treatment outcomes in patients receiving second-line HAI with 5-FU or mitomycin C, after first-line HAI of oxaliplatin in heavily pretreated patients. Between March 2010 and June 2016, this observational study included 24 patients with unresectable CRC LM and treated with HAI of 5-FU (17 patients) or mitomycin C (7 patients), after HAI of oxaliplatin. Mean age was 61.7 years. Forty-two percent of patients (10/24) had extra-hepatic metastases and 75% (18/24) at least 8 liver metastases. Including HAI of oxaliplatin, all patients had previously received at least 2 lines of chemotherapy±targeted agents (100%) and 96% (23/24) received concomitant systemic therapies together with HAI of 5-FU or mitomycin C. The overall objective response rate and disease control rate were, respectively, 42% (10/24) and 71% (17/24). Median progression-free survival and overall survival (OS) were, respectively, 5.6 and 25.8 months; hepatic progression-free survival was 8.5months. Thirteen percent (3/24) of the patients received further curative intent treatment after HAI 5-FU and mitomycin C. No toxic death occurred and the toxicity profile was acceptable. HAI of 5-FU or mitomycin C is an alternative option in patients with predominant CRC LM, when they experience disease progression or do not tolerate HAI of oxaliplatin. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  11. The efficiency of CD40 down regulation by siRNA and antisense ODN: comparison of lipofectamine and FuGENE6.

    Science.gov (United States)

    Ebadi, Padideh; Karimi, Mohammad Hossein; Pourfathollah, Ali Akbar; Saheb Ghadam Lotfi, Abbas; Soheili, Zahra Soheila; Samiee, Shahram; Hajati, Smerdis; Nadali, Fatemeh; Geramizadeh, Bita; Moazzeni, Seyyed Mohammad

    2009-03-01

    Dendritic cells (DCs) are ideal accessory cells in the field of gene therapy. Delivery of DNA and siRNA into mammalian cells is a useful technique in treating various diseases caused by single gene defects. Selective gene silencing by small interfering RNAs (siRNAs) and antisense oligodeoxynucleotides (ODN)s is an efficient method for the manipulation of cellular functions. An efficient, functional delivery system with no toxicity problems would be attractive. We compared two commercially available cationic lipids, Lipofectamine and FuGENE6, in the delivery of both siRNA and antisense ODNs into mice spleen-derived DCs. Cellular uptake was measured by the means of fluorescein-labelled non-silencing siRNA and antisense ODNs as a model system using flow cytometry. Cytotoxicity of the two delivery systems was compared with propidium iodide and annexin-V staining, and quantified with flow cytometry. The efficiency of our oligonucleotide delivery systems was compared by measuring CD40 expression by flow cytometry. CD40 expression in DCs was 38%. After siRNA transfection by Lipofectamine, CD40 expression decreased to 13%, and after transfection by FuGENE6, it decreased to 18%. The difference was statistically significant. CD40 down regulation in DCs transfected with the two different antisense sequences by Lipofectamine was 21% and 23%, and down regulation after transfection by FuGENE6 was 19% and 18%, respectively. The differences were not statistically significant. The effects of siRNA and antisense ODNs were specific. Lipofectamine was a more potent delivery system in siRNA effect, followed by FuGENE6. There was no significant difference between Lipofectamine and FuGENE6 as a delivery system of antisense ODNs.

  12. Combined 5-FU and ChoKα inhibitors as a new alternative therapy of colorectal cancer: evidence in human tumor-derived cell lines and mouse xenografts.

    Directory of Open Access Journals (Sweden)

    Ana de la Cueva

    Full Text Available Colorectal cancer (CRC is the third major cause of cancer related deaths in the world. 5-fluorouracil (5-FU is widely used for the treatment of colorectal cancer but as a single-agent renders low response rates. Choline kinase alpha (ChoKα, an enzyme that plays a role in cell proliferation and transformation, has been reported overexpressed in many different tumors, including colorectal tumors. ChoKα inhibitors have recently entered clinical trials as a novel antitumor strategy.ChoKα specific inhibitors, MN58b and TCD-717, have demonstrated a potent antitumoral activity both in vitro and in vivo against several tumor-derived cell line xenografts including CRC-derived cell lines. The effect of ChoKα inhibitors in combination with 5-FU as a new alternative for the treatment of colon tumors has been investigated both in vitro in CRC-tumour derived cell lines, and in vivo in mouse xenografts models. The effects on thymidilate synthase (TS and thymidine kinase (TK1 levels, two enzymes known to play an essential role in the mechanism of action of 5-FU, were analyzed by western blotting and quantitative PCR analysis. The combination of 5-FU with ChoKα inhibitors resulted in a synergistic effect in vitro in three different human colon cancer cell lines, and in vivo against human colon xenografts in nude mice. ChoKα inhibitors modulate the expression levels of TS and TK1 through inhibition of E2F production, providing a rational for its mechanism of action.Our data suggest that both drugs in combination display a synergistic antitumoral effect due to ChoKα inhibitors-driven modulation of the metabolization of 5-FU. The clinical relevance of these findings is strongly supported since TCD-717 has recently entered Phase I clinical trials against solid tumors.

  13. Phase II study of neoadjuvant 5-FU + leucovorin + CPT-11 in patients with resectable liver metastases from colorectal adenocarcinoma

    Directory of Open Access Journals (Sweden)

    Bigam David

    2004-07-01

    Full Text Available Abstract Background Following resection of liver metastases from colorectal cancer, 5-year survivals are reportedly 30 – 39%. It can be assumed that this clinical situation represents systemic disease. Therefore, it is postulated that systemic chemotherapy would improve outcomes, particularly in those whose disease is sensitive to the agents administered. One potential advantage of neoadjuvant chemotherapy is that it provides in vivo chemosensitivity data. Response to neoadjuvant chemotherapy could therefore guide adjuvant chemotherapy following resection of liver metastases from colorectal cancer. Methods and design This is a prospective Phase II evaluation of outcomes in patients with potentially resectable liver metastases. Patients will receive neoadjuvant chemotherapy and will undergo resection. Postoperative chemotherapy will be directed by the degree of response to preoperative chemotherapy. All patients with Stage IV colorectal adenocarcinoma isolated to the liver that have disease that is amenable to complete ablation by resection, radiofrequency ablation, and/or cryoablation will be candidates for the trial. Patients will receive CPT-11 180 mg/m2 IV (over 90 minutes on day 1 with 5-FU 400 mg/m2 bolus and 600 mg/m2 by 22 hour infusion and calcium folinate 200 mg/m2 on days 1 and 2, every 2 weeks. Altogether, six cycles of chemotherapy will be administered. Patients will then undergo resection and/or radiofrequency ablation. Patients who had stable disease or a clinical response with preoperative chemotherapy will receive an additional 12 cycles of CPT-11 180 mg/m2 IV (over 90 minutes on day 1 with 5-FU 400 mg/m2 bolus and 600 mg/m2 by 22 hour infusion and calcium folinate 200 mg/m2 on days 1 and 2 (given every 2 weeks. Patients with resectable disease who had progressive disease during neoadjuvant chemotherapy will receive best supportive care or an alternative agent, at the discretion of the treating physician. Those patients who are

  14. The Many Sides of Happy Lim: aka Hom Ah Wing, Lin Jian Fu, Happy Lum, Lin Chien Fu, Hom Yen Chuck, Lam Kin Foo, Lum Kin Foo, Hom, Lim Goon Wing, Lim Gin Foo, Gin Foo Lin, Koon Wing Lim, Henry Chin, Lim Ying Chuck, Lim Ah Wing, et. al.

    Directory of Open Access Journals (Sweden)

    Gordon H. Chang

    2010-03-01

    Full Text Available

    Known to the FBI, INS, and IRS as Mr. Ah Wing Hom, he was also Lin Jian Fu, Jian Fu (Tough Guy, or just Fu to the readers of the many poems and short stories he published in Chinese over four decades in the twentieth century. And to still others, primarily English-readers of his writing, he was Happy Lim, an ironic, even tragically bizarre name, as his life was far from pleasant. On New Year's Day 1986, he died alone in a dingy San Francisco Chinatown bachelor hotel suffering from a bacterial infection and a chronic blood disorder that had required the amputation of all his toes the year before. He was seventy-eight years of age and had spent most of his life within blocks of where he died.

  15. The Many Sides of Happy Lim: aka Hom Ah Wing, Lin Jian Fu, Happy Lum, Lin Chien Fu, Hom Yen Chuck, Lam Kin Foo, Lum Kin Foo, Hom, Lim Goon Wing, Lim Gin Foo, Gin Foo Lin, Koon Wing Lim, Henry Chin, Lim Ying Chuck, Lim Ah Wing, et. al.

    Directory of Open Access Journals (Sweden)

    Gordon H. Chang

    2010-03-01

    Full Text Available Known to the FBI, INS, and IRS as Mr. Ah Wing Hom, he was also Lin Jian Fu, Jian Fu (Tough Guy, or just Fu to the readers of the many poems and short stories he published in Chinese over four decades in the twentieth century. And to still others, primarily English-readers of his writing, he was Happy Lim, an ironic, even tragically bizarre name, as his life was far from pleasant. On New Year's Day 1986, he died alone in a dingy San Francisco Chinatown bachelor hotel suffering from a bacterial infection and a chronic blood disorder that had required the amputation of all his toes the year before. He was seventy-eight years of age and had spent most of his life within blocks of where he died.

  16. ELECTROMYOGRAPHIC STUDY OF A SEQUENCE OF YAU-MAN KUNG FU PALM STRIKES WITH AND WITHOUT IMPACT

    Directory of Open Access Journals (Sweden)

    Osmar Pinto Neto

    2007-10-01

    Full Text Available In martial arts and contact sports, strikes are often trained in two different ways: with and without impacts. This study aims to compare the electromyographical activity (EMG of the triceps brachii (TB, biceps brachii (BB and brachioradialis (BR muscles during strikes with and without impacts. Eight Yau-Man Kung Fu practitioners participated in the experiment. Each participant performed 5 sequences of 5 consecutive KF Yau-Man palm strikes with no impact intercalated with 5 sequences of 5 repetitions targeting a KF training shield. Surface EMG signals were obtained from the TB, BB, and RB for 3.0 seconds using an eight-channel module with a total amplifier gain of 2000 and sampled at 3500 Hz. The EMG analyses were done in the time (rms and frequency (wavelet domains. For the frequency domain, Morlet wavelet power spectra were obtained and an original method was used to quantify statistically significant regions on the power spectra. The results both in the time and frequency domains indicate a higher TB and BR muscle activity for the strikes with impacts. No significant difference was found for the BB in the two different scenarios. In addition, the results show that the wavelet power spectra pattern for the three analysed muscles obtained from the strikes with and without impacts were similar

  17. Epigenetic silencing of ASPP1 confers 5-FU resistance in clear cell renal cell carcinoma by preventing p53 activation.

    Science.gov (United States)

    Wang, Xingwen; Cheng, Yiwei; Zhu, YiFu; Li, Huayi; Ge, Wenjie; Wu, Xiaoliang; Zhao, Kunming; Yuan, Jinyang; Li, Zhenglin; Jiang, Shijian; Han, Zhengbin; Jiang, Qinghua; Wu, Qiong; Liu, Tao; Zhang, Cheng; Yu, Miao; Hu, Ying

    2017-10-01

    Inactivation of p53 has been shown to correlate with drug resistance in tumors. However, in clear cell renal cell carcinoma (ccRCC), p53 is rarely mutated, yet the tumors remain highly insensitive to the conventional chemotherapeutic drugs. The underlying mechanisms responsible for the non-genetic p53 inactivation remain obscure. Here, we report, for the first time, that Apoptosis Stimulating of P53 Protein 1 (ASPP1) was remarkably downregulated at both mRNA (about 3.9-fold) and protein (about 4.9-fold) levels in ccRCC human specimens in comparison with the paired normal controls. In addition, lower ASPP1 was closely related to the higher grade of tumors and shorter life expectancy of ccRCC patients, both with p p53 targets expression and p53 target PIG3 luciferase reporter activation. In contrast, ASPP1 knockdown promoted cell growth and prevent 5-FU-induced p53 activation and apoptosis. In conclusion, our results suggest that ASPP1 silencing is one of dominate mechanisms in inhibiting wild type p53 in ccRCC. ASPP1, therefore, may be potentially used as a promising biomarker for prognosis and therapeutic intervention in ccRCC. © 2017 UICC.

  18. Technical note: Fu-Liou-Gu and Corti-Peter model performance evaluation for radiative retrievals from cirrus clouds

    Science.gov (United States)

    Lolli, Simone; Campbell, James R.; Lewis, Jasper R.; Gu, Yu; Welton, Ellsworth J.

    2017-06-01

    We compare, for the first time, the performance of a simplified atmospheric radiative transfer algorithm package, the Corti-Peter (CP) model, versus the more complex Fu-Liou-Gu (FLG) model, for resolving top-of-the-atmosphere radiative forcing characteristics from single-layer cirrus clouds obtained from the NASA Micro-Pulse Lidar Network database in 2010 and 2011 at Singapore and in Greenbelt, Maryland, USA, in 2012. Specifically, CP simplifies calculation of both clear-sky longwave and shortwave radiation through regression analysis applied to radiative calculations, which contributes significantly to differences between the two. The results of the intercomparison show that differences in annual net top-of-the-atmosphere (TOA) cloud radiative forcing can reach 65 %. This is particularly true when land surface temperatures are warmer than 288 K, where the CP regression analysis becomes less accurate. CP proves useful for first-order estimates of TOA cirrus cloud forcing, but may not be suitable for quantitative accuracy, including the absolute sign of cirrus cloud daytime TOA forcing that can readily oscillate around zero globally.

  19. Gauge-theoretic invariants for topological insulators: a bridge between Berry, Wess-Zumino, and Fu-Kane-Mele

    Science.gov (United States)

    Monaco, Domenico; Tauber, Clément

    2017-07-01

    We establish a connection between two recently proposed approaches to the understanding of the geometric origin of the Fu-Kane-Mele invariant FKM\\in Z_2, arising in the context of two-dimensional time-reversal symmetric topological insulators. On the one hand, the Z_2 invariant can be formulated in terms of the Berry connection and the Berry curvature of the Bloch bundle of occupied states over the Brillouin torus. On the other, using techniques from the theory of bundle gerbes, it is possible to provide an expression for FKM containing the square root of the Wess-Zumino amplitude for a certain U( N)-valued field over the Brillouin torus. We link the two formulas by showing directly the equality between the above-mentioned Wess-Zumino amplitude and the Berry phase, as well as between their square roots. An essential tool of independent interest is an equivariant version of the adjoint Polyakov-Wiegmann formula for fields T^2 → U(N), of which we provide a proof employing only basic homotopy theory and circumventing the language of bundle gerbes.

  20. In vivo experimental testing of the FW axial blood pump for left ventricular support in Fu Wai Hospital.

    Science.gov (United States)

    Zhang, Yan; Hu, Sheng-Shou; Zhou, Jian-Ye; Sun, Han-Song; Tang, Yue; Zhang, Hao; Zheng, Zhe; Li, Guo-Rong; Zhu, Xiao-Dong; Gui, Xin-Min

    2009-01-01

    A fully implantable, axial flow blood pump has been developed in Fu Wai Hospital aiming for clinical use. This ventricular assist device (VAD), which was developed after numerous CFD analyses for the flow characteristics of the pump, is 58.5-mm long, 30-mm wide (including DC motor), and weighs 240 g. The pump can deliver 5 L/min for pressures of 100 mm Hg over 8,000 rpm. In this study, short-term hemocompatibility effects of the axial left ventricular assist device (LVAD) (FW blood pump) were evaluated in four healthy sheep. The device was implanted into the left ventricular apex of beating hearts. The outflow graft of each device was anastomosed to the descending aorta. The hemolysis, which was evaluated in vivo by free hemoglobin value, was below 30 mg/dL. Evaluation of serum biochemical data showed that implantation of the FW blood pump in sheep with normal hearts did not impair end organ function. Gross and microscopic sections of kidney, liver, and lung revealed no evidence of microemboli. Performance of the pump in vivo was considered sufficient for a LVAD, although further design improvement is necessary in terms of hemolysis and antithrombosis to improve biocompatibility of the pump.