A modelling and control structure for product quality control in climate-controlled processing of agro-material

NARCIS (Netherlands)

Verdijck, G.J.C.; Straten, van G.

2002-01-01

In this paper a modelling and control structure for product quality control is presented for a class of operations that processes agro-material. This class can be characterised as climate-controlled operations, such as storage, transport and drying. The basic model consists of three parts. These are

Formulation and quality control of a topical gel product for treatment of melasmaFormulation and quality control of a topical gel product for treatment of melasma

Directory of Open Access Journals (Sweden)

A. Ketabi

2017-11-01

Full Text Available Background and objectives: Melasma is one of the most common pigmentary disorders. It has a considerable impact on quality of life. The treatment of melasma has still remained a challenge because the efficient treatment has not been proven until now and there is still a need to find new depigmenting products.Allium cepa L. and Cucumis melo L. seeds as well as tragacanth have been introduced in Iranian traditional medicine (ITM as depigmenting agents. Moreover, modern studies have shown their antioxidant and inhibitory mushroom tyrosinase effect.In this study, a topical gel containing Allium cepa L. and Cucumis melo L. seeds extract was prepared with tragacanth and quality control evaluations have been accomplished. Method: After performing quality control of plants seeds and tragacanth according to pharmacopoeia, the ethanol extract of A. cepa and hydroalcoholic extract of C. melo seeds were prepared. An appropriate gel formulation was selected on the base of suitable viscosity. The gel product was formulated using 5% of each plant extracts in tragacanth gel base. In addition, the herbal gel was evaluated using pharmaceutical behavior such as physical appearance, pH, viscosity, spreadability as well as phenolics content. Results: The herbal gel product showed acceptable pharmaceutical behavior as well as considerable phenolic content (1.43±0.01 mg/g. Conclusion: The prepared topical gel product could be a good natural formulation candidate for clinical studies in the field of hyperpigmentation. Moreover, phenolic content of the product could be considered as an indicator for its quality control.

Non-destructive methods and means for quality control of structural products

International Nuclear Information System (INIS)

Dmitriev, V.V.

1989-01-01

Progressive non-destructive methods (acoustic, magnetic, radiation with liquid penetrants) and means of control of structural product quality, allowing to determine the state of products and structures not only immediately after their production but directly at the erected or reconstructed objects are described

Statistical process control: An approach to quality assurance in the production of vitrified nuclear waste

International Nuclear Information System (INIS)

Pulsipher, B.A.; Kuhn, W.L.

1987-01-01

Current planning for liquid high-level nuclear wastes existing in the United States includes processing in a liquid-fed ceramic melter to incorporate it into a high-quality glass, and placement in a deep geologic repository. The nuclear waste vitrification process requires assurance of a quality product with little or no final inspection. Statistical process control (SPC) is a quantitative approach to one quality assurance aspect of vitrified nuclear waste. This method for monitoring and controlling a process in the presence of uncertainties provides a statistical basis for decisions concerning product quality improvement. Statistical process control is shown to be a feasible and beneficial tool to help the waste glass producers demonstrate that the vitrification process can be controlled sufficiently to produce an acceptable product. This quantitative aspect of quality assurance could be an effective means of establishing confidence in the claims to a quality product

Statistical process control: An approach to quality assurance in the production of vitrified nuclear waste

International Nuclear Information System (INIS)

Pulsipher, B.A.; Kuhn, W.L.

1987-02-01

Current planning for liquid high-level nuclear wastes existing in the US includes processing in a liquid-fed ceramic melter to incorporate it into a high-quality glass, and placement in a deep geologic repository. The nuclear waste vitrification process requires assurance of a quality product with little or no final inspection. Statistical process control (SPC) is a quantitative approach to one quality assurance aspect of vitrified nuclear waste. This method for monitoring and controlling a process in the presence of uncertainties provides a statistical basis for decisions concerning product quality improvement. Statistical process control is shown to be a feasible and beneficial tool to help the waste glass producers demonstrate that the vitrification process can be controlled sufficiently to produce an acceptable product. This quantitative aspect of quality assurance could be an effective means of establishing confidence in the claims to a quality product. 2 refs., 4 figs

[Investigation on production process quality control of traditional Chinese medicine--Banlangen granule as an example].

Science.gov (United States)

Tan, Manrong; Yan, Dan; Qiu, Lingling; Chen, Longhu; Yan, Yan; Jin, Cheng; Li, Hanbing; Xiao, Xiaohe

2012-04-01

For the quality management system of herbal medicines, intermediate and finished products it exists the " short board" effect of methodologies. Based on the concept of process control, new strategies and new methods of the production process quality control had been established with the consideration of the actual production of traditional Chinese medicine an the characteristics of Chinese medicine. Taking Banlangen granule as a practice example, which was effective and widespread application, character identification, determination of index components, chemical fingerprint and biometrics technology were sequentially used respectively to assess the quality of Banlangen herbal medicines, intermediate (water extraction and alcohol precipitation) and finished product. With the transfer rate of chemical information and biological potency as indicators, the effectiveness and transmission of the above different assessments and control methods had been researched. And ultimately, the process quality control methods of Banlangen granule, which were based on chemical composition analysis-biometric analysis, had been set up. It can not only validly solute the current status that there were many manufacturers varying quality of Banlangen granule, but also ensure and enhance its clinical efficacy. Furthermore it provided a foundation for the construction of the quality control of traditional Chinese medicine production process.

Structural modeling of the production quality as a multidimensional object of measurement and control

OpenAIRE

Зубрецкая, Наталья Анатольевна

2015-01-01

The structural-analytical models of product quality as a multidimensional process of evaluation, measurement and control are developed. The product quality is represented as a multi-factor, multi-criteria and multi-parameter estimation object. This structural formalization of quality demonstrates the multidimensional qualities: comprehensiveness due to a set of environmental factors; multicriteriality due collectively evaluated quality criteria; multiparameter information models that describe...

Application of the suggestion system in the improvement of the production process and product quality control

Science.gov (United States)

Gołaś, H.; Mazur, A.; Gruszka, J.; Szafer, P.

2016-08-01

The elaboration is a case study and the research was carried out in the company Alco-Mot Ltd., which employs 120 people. The company specializes in the production of lead poles for industrial and traction batteries using gravity casting. The elements embedded in the cast are manufactured on a machining centre, which provides the stability of the process and of the dimensions of the product as well as a very short production time. As a result of observation and analysis the authors have developed a concept for the implementation of a dynamic suggestion system in ALCO-MOT, including, among others, a standard for actions in the implementation of the suggestion system, as well as clear guidelines for the processing and presentation of the activities undertaken in the time between the establishment of the concept (suggestions) and the benefits analysis after the proposed solutions have been implemented. The authors also present how suggestions proposed by ALCO-MOT staff contributed to the improvement of the processes of production and quality control. Employees offered more than 30 suggestions, of which more than a half are being implemented now and further actions are being prepared for implementation. The authors will present the results of improvements in, for example, tool replacement time, scrap reduction. The authors will present how kaizen can improve the production and quality control processes. They will present how the production and quality control processes looked before and after the implementation of employee suggestions.

QUALITY CONTROL OF SOME TRADITIONAL MEAT PRODUCTS

Directory of Open Access Journals (Sweden)

S. DOBRINAS

2014-03-01

Full Text Available In this paper, we present the characterization of six traditional meat products: smoked file, smoked bacon, pork sausages, sausage prepared from swine’s entrails, pork pastrami, sheep sausages. Organoleptic tests (the aspect and shape, the aspect of freshly cut in the section, smell, taste and consistency, physico-chemical and microbiological determinations (NTG, Salmonella, Listeria monocytogenes and Escherichia coli were performed. These analyzes are a part of quality control that must be done in order to obtain a certificate from the Ministry of Agriculture for a traditional product. After identification of H2S and starch and according to fat oxidation degree it was concluded that analyzed samples didn’t contain counterfeiters and all parameters analyzed are within the maximum limits allowed by law. Considering all the procedures for manufacturing, characteristics of raw and auxiliary materials, organoleptic properties of final products analyzed in this study, it can be concluded that analyzed meat specialties meet the requirements of Ministry Order no. 690/28.09.2004 for the traditional products certification.

Application of Metabolomics to Quality Control of Natural Product Derived Medicines.

Science.gov (United States)

Lee, Kyung-Min; Jeon, Jun-Yeong; Lee, Byeong-Ju; Lee, Hwanhui; Choi, Hyung-Kyoon

2017-11-01

Metabolomics has been used as a powerful tool for the analysis and quality assessment of the natural product (NP)-derived medicines. It is increasingly being used in the quality control and standardization of NP-derived medicines because they are composed of hundreds of natural compounds. The most common techniques that are used in metabolomics consist of NMR, GC-MS, and LC-MS in combination with multivariate statistical analyses including principal components analysis (PCA) and partial least squares-discriminant analysis (PLS-DA). Currently, the quality control of the NP-derived medicines is usually conducted using HPLC and is specified by one or two indicators. To create a superior quality control framework and avoid adulterated drugs, it is necessary to be able to determine and establish standards based on multiple ingredients using metabolic profiling and fingerprinting. Therefore, the application of various analytical tools in the quality control of NP-derived medicines forms the major part of this review. Veregen ® (Medigene AG, Planegg/Martinsried, Germany), which is the first botanical prescription drug approved by US Food and Drug Administration, is reviewed as an example that will hopefully provide future directions and perspectives on metabolomics technologies available for the quality control of NP-derived medicines.

Quality transitivity and traceability system of herbal medicine products based on quality markers.

Science.gov (United States)

Liu, Changxiao; Guo, De-An; Liu, Liang

2018-05-15

Due to a variety of factors to affect the herb quality, the existing quality management model is unable to evaluate the process control. The development of the concept of "quality marker" (Q-marker) lays basis for establishing an independent process quality control system for herbal products. To ensure the highest degree of safety, effectiveness and quality process control of herbal products, it is aimed to establish a quality transitivity and traceability system of quality and process control from raw materials to finished herbal products. Based on the key issues and challenges of quality assessment, the current status of quality and process controls from raw materials to herbal medicinal products listed in Pharmacopoeia were analyzed and the research models including discovery and identification of Q-markers, analysis and quality management of risk evaluation were designed. Authors introduced a few new technologies and methodologies, such as DNA barcoding, chromatographic technologies, fingerprint analysis, chemical markers, bio-responses, risk management and solution for quality process control. The quality and process control models for herbal medicinal products were proposed and the transitivity and traceability system from raw materials to the finished products was constructed to improve the herbal quality from the entire supply and production chain. The transitivity and traceability system has been established based on quality markers, especially on how to control the production process under Good Engineering Practices, as well as to implement the risk management for quality and process control in herbal medicine production. Copyright © 2018 Elsevier GmbH. All rights reserved.

Electronic Nose for Microbiological Quality Control of Food Products

Directory of Open Access Journals (Sweden)

M. Falasconi

2012-01-01

Full Text Available Electronic noses (ENs have recently emerged as valuable candidates in various areas of food quality control and traceability, including microbial contamination diagnosis. In this paper, the EN technology for microbiological screening of food products is reviewed. Four paradigmatic and diverse case studies are presented: (a Alicyclobacillus spp. spoilage of fruit juices, (b early detection of microbial contamination in processed tomatoes, (c screening of fungal and fumonisin contamination of maize grains, and (d fungal contamination on green coffee beans. Despite many successful results, the high intrinsic variability of food samples together with persisting limits of the sensor technology still impairs ENs trustful applications at the industrial scale. Both advantages and drawbacks of sensor technology in food quality control are discussed. Finally, recent trends and future directions are illustrated.

Quality Control for Expanded Tsetse Production, Sterilization and Field Application

International Nuclear Information System (INIS)

2012-07-01

The use of the sterile insect technique (SIT) for the control of pest insects as part of an integrated, area-wide approach is widely accepted. Its application for the eradication of different tsetse flies, the vectors of human sleeping sickness and African animal trypanosomosis, is attracting increasing interest. Following several initial demonstrations of the application of the SIT for tsetse control the technique was applied on the island of Unguja, Zanzibar, in the mid-1990s and, as the final component of an integrated control programme, led to the eradication of the only tsetse species on the island, Glossina austeni. This successful programme encouraged a number of countries to embark on projects with an SIT component for tsetse control, most Ethiopia. In 2001 the Pan African Tsetse and Trypanosomosis Eradication Campaign (PATTEC) was launched by the Organization of African Unity (now African Union, AU) and, subsequently, six countries obtained funding from the African Development Bank (AfDB) in 2005 to support control programmes with an SIT component. A further six countries have subsequently requested AfDB funding for their programmes. The FAO/IAEA coordinated research project (CRP) on Automation for Tsetse Mass Rearing For Use in Sterile Insect Technique Programmes, which was completed in 2001, led to the development of a semi-automated system for tsetse production. Using this new system, a large rearing facility was established in Addis Ababa, Ethiopia, to supply sterile males for an elimination programme in the southern Rift Valley. The development of large-scale rearing highlighted the need for improved quality control procedures and, with this in mind, the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture established a CRP in 2003 entitled Improved and Harmonized Quality Control for Expanded Tsetse Production, Sterilization and Field Application with the Objective of Improving and Expanding the Quality Control Sections of the FAO

Quality Control for Expanded Tsetse Production, Sterilization and Field Application

Energy Technology Data Exchange (ETDEWEB)

NONE

2012-07-15

The use of the sterile insect technique (SIT) for the control of pest insects as part of an integrated, area-wide approach is widely accepted. Its application for the eradication of different tsetse flies, the vectors of human sleeping sickness and African animal trypanosomosis, is attracting increasing interest. Following several initial demonstrations of the application of the SIT for tsetse control the technique was applied on the island of Unguja, Zanzibar, in the mid-1990s and, as the final component of an integrated control programme, led to the eradication of the only tsetse species on the island, Glossina austeni. This successful programme encouraged a number of countries to embark on projects with an SIT component for tsetse control, most Ethiopia. In 2001 the Pan African Tsetse and Trypanosomosis Eradication Campaign (PATTEC) was launched by the Organization of African Unity (now African Union, AU) and, subsequently, six countries obtained funding from the African Development Bank (AfDB) in 2005 to support control programmes with an SIT component. A further six countries have subsequently requested AfDB funding for their programmes. The FAO/IAEA coordinated research project (CRP) on Automation for Tsetse Mass Rearing For Use in Sterile Insect Technique Programmes, which was completed in 2001, led to the development of a semi-automated system for tsetse production. Using this new system, a large rearing facility was established in Addis Ababa, Ethiopia, to supply sterile males for an elimination programme in the southern Rift Valley. The development of large-scale rearing highlighted the need for improved quality control procedures and, with this in mind, the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture established a CRP in 2003 entitled Improved and Harmonized Quality Control for Expanded Tsetse Production, Sterilization and Field Application with the Objective of Improving and Expanding the Quality Control Sections of the FAO

Bulk H analysis using neutrons for routine quality control of cassava and products

International Nuclear Information System (INIS)

Jonah, S.A.; Okunade, I.O.; Abolude, O.; Onyike, E.; Inuwa, I.M.

2011-01-01

Nuclear and related techniques are useful in addressing the issues of food security and safety facing the world today, via quality control of raw materials and products. In this work, experimental investigations were performed to assess the use of total hydrogen content in cassava and products as a quality control indicator of starch and cyanide contents. The work was carried out using a neutron reflection facility at the Centre for Energy Research and Training, Ahmadu Bello University, Zaria, Nigeria. Cassava samples and products were obtained from retail outlets of Ibadan, Umudike and Zaria, representing three major regions of Nigeria. In general, data obtained indicate a total hydrogen content range of 4.47±0.11-10.71±0.27 wt% for the various samples, including raw, dry and processed cassava. Results show that samples having low hydrogen content are generally rich in cyanide compounds and demonstrate an inverse relationship between hydrogen content and cyanide content. The implication of this is that the neutron reflection facility can be used as a quality control setup for routine determination of hydrogen as an indicator of the cyanide content in cassava and products.

Uneven batch data alignment with application to the control of batch end-product quality.

Science.gov (United States)

Wan, Jian; Marjanovic, Ognjen; Lennox, Barry

2014-03-01

Batch processes are commonly characterized by uneven trajectories due to the existence of batch-to-batch variations. The batch end-product quality is usually measured at the end of these uneven trajectories. It is necessary to align the time differences for both the measured trajectories and the batch end-product quality in order to implement statistical process monitoring and control schemes. Apart from synchronizing trajectories with variable lengths using an indicator variable or dynamic time warping, this paper proposes a novel approach to align uneven batch data by identifying short-window PCA&PLS models at first and then applying these identified models to extend shorter trajectories and predict future batch end-product quality. Furthermore, uneven batch data can also be aligned to be a specified batch length using moving window estimation. The proposed approach and its application to the control of batch end-product quality are demonstrated with a simulated example of fed-batch fermentation for penicillin production. Copyright © 2013 ISA. Published by Elsevier Ltd. All rights reserved.

Quality Management, Quality Assurance and Quality Control in Blood Establishments

OpenAIRE

Bolbate, N

2008-01-01

Quality terms and the roots of the matter are analyzed according to European Committee’s recommendations. Essence of process and product quality control as well as essence of quality assurance is described. Quality system’s structure including quality control, quality assurance and management is justified in the article.

Quality control in the fuel elements production process

International Nuclear Information System (INIS)

Katanic-Popovic, J.; Spasic, Z.; Djuricis, Lj.

1977-01-01

Recently great attention has been paid at the international level to the analysis of production processes and quality control of fuel and fuel elements with the aim to speed up activity of proposing and accepting standards and measurement methods. IAEA also devoted great interest to these problems appealing to more active participation of all users and producers fuel elements in a general effort to secure successful work of nuclear plants. For adequate and timely participation in future in the establishment and analysis of general requirements and documentation for the control of purchased or self produced fuel elements in out country it is necessary to be well informed and to follow this activity at the international level. (author)

The assessment of quality of products using selected quality instruments

Directory of Open Access Journals (Sweden)

Edyta Kardas

2016-03-01

Full Text Available The quality parameters of products should be controlled at every stage of the production process, since it allows detection of any problems even in the initial stages of production processes and removes their causes during manufacturing. Final control of products is intended to capture non-conforming products that did not go to the customers. The results of such controls should constantly be analysed. Such analysis can help to detect the most common problems, determine some dependences or identify the causes of such situations. A lot of different instruments that can support improvement of processes can be used for this kind of analysis. The paper presents the possibility of using some tools which can be utilized to support the analysis and assessment of quality of products at different stages of the production process. The quality analysis of exemplary products using selected quality methods and tolls is carried out. Metal sleeve, that is part of electronic control subassembly of anti-blocking system of ABS, which was the research component being studied.

Production system with process quality control: modelling and application

Science.gov (United States)

Tsou, Jia-Chi

2010-07-01

Over the past decade, there has been a great deal of research dedicated to the study of quality and the economics of production. In this article, we develop a dynamic model which is based on the hypothesis of a traditional economic production quantity model. Taguchi's cost of poor quality is used to evaluate the cost of poor quality in the dynamic production system. A practical case from the automotive industry, which uses the Six-sigma DMAIC methodology, is discussed to verify the proposed model. This study shows that there is an optimal value of quality investment to make the production system reach a reasonable quality level and minimise the production cost. Based on our model, the management can adjust its investment in quality improvement to generate considerable financial return.

Improved GMP-compliant multi-dose production and quality control of 6-[18F]fluoro-L-DOPA.

Science.gov (United States)

Luurtsema, G; Boersma, H H; Schepers, M; de Vries, A M T; Maas, B; Zijlma, R; de Vries, E F J; Elsinga, P H

2017-01-01

6-[ 18 F]Fluoro-L-3,4-dihydroxyphenylalanine (FDOPA) is a frequently used radiopharmaceutical for detecting neuroendocrine and brain tumors and for the differential diagnosis of Parkinson's disease. To meet the demand for FDOPA, a high-yield GMP-compliant production method is required. Therefore, this study aimed to improve the FDOPA production and quality control procedures to enable distribution of the radiopharmaceutical over distances.FDOPA was prepared by electrophilic fluorination of the trimethylstannyl precursor with [ 18 F]F 2 , produced from [ 18 O] 2 via the double-shoot approach, leading to FDOPA with higher specific activity as compared to FDOPA which was synthesized, using [ 18 F]F 2 produced from 20 Ne, leading to FDOPA with a lower specific activity. The quality control of the product was performed using a validated UPLC system and compared with quality control with a conventional HPLC system. Impurities were identified using UPLC-MS. The [ 18 O] 2 double-shoot radionuclide production method yielded significantly more [ 18 F]F 2 with less carrier F 2 than the conventional method starting from 20 Ne. After adjustment of radiolabeling parameters substantially higher amounts of FDOPA with higher specific activity could be obtained. Quality control by UPLC was much faster and detected more side-products than HPLC. UPLC-MS showed that the most important side-product was FDOPA-quinone, rather than 6-hydroxydopa as suggested by the European Pharmacopoeia. The production and quality control of FDOPA were significantly improved by introducing the [ 18 O] 2 double-shoot radionuclide production method, and product analysis by UPLC, respectively. As a result, FDOPA is now routinely available for clinical practice and for distribution over distances.

14 CFR 21.139 - Quality control.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Quality control. 21.139 Section 21.139... PROCEDURES FOR PRODUCTS AND PARTS Production Certificates § 21.139 Quality control. The applicant must show that he has established and can maintain a quality control system for any product, for which he...

Quality control of clinker products by SEM and XRF analysis

International Nuclear Information System (INIS)

Ziad Abu Kaddourah; Khairun Azizi

1996-01-01

The microstructure and chemical properties of industrial Portland cement clinkers have been examined by SEM and XRF methods to establish the nature of the clinkers and how variations in the clinker characteristics can be used to control the clinker quality. The clinker nodules were found to show differences in the chemical composition and microstructure between the inner and outer parts of the clinker nodules. Microstructure studies of industrial Portland cement clinker have shown that the outer part of the nodules are enriched in silicate more than the inner part. There is better crystallization and larger alite crystal size in the outer part than in the inner part. The alite crystal size varied between 16.2 -46.12 μ m. The clinker chemical composition was found to affect the residual >45 μ m, where a higher belite content causes an increase in the residual >45 μ m in the the cement product and will cause a decrease in the concrete strength of the cement product. The aluminate and ferrite crystals and the microcracks within the alite crystal are clear in some clinker only. The quality of the raw material preparation, burning and cooling stages can be controlled using the microstructure of the clinker product

Production control system specified quality sausage products

Directory of Open Access Journals (Sweden)

A. V. Tokarev

2016-01-01

Full Text Available The problem of management of production target in technological system of production of sausages of the set quality is considered in article. Decomposition of technological system is considered. Functions of management are allocated: formation of an optimum compounding of forcemeat, expert analysis of a compounding, laboratory analysis of a compounding and its statement. Information technology of interaction of these functions is offered. The mathematical problem definition of finding of an optimum compounding meat product with use of possible substitutes of ingredients is presented. This mathematical problem is a classical linear programming problem whose solution has the standard program. Since the manufacture of the finished product are various nonlinear effects are taken into account at the present time it is practically impossible, the methodology provided in this operation "Expert analysis of the formulation" and "Laboratory analysis of the finished product." An example of calculating the optimum alternative base recipe "Sausages “Viennese with cheese”" TS 9213-010-40155161-2002. For an alternative formulation demands were made at a cost of meat, the ingredient composition, as well as the final product organoleptic and physic-chemical indicators should comply with regulatory requirements "Sausages “Viennese with cheese”" TS 9213-010-40155161-2002. Indicator acid activity (pH calculated stuffing formulation should be in the range 6.0-6.3. As a partial replacement for the main raw material have been proposed acceptable substitutes. It was necessary to calculate on the basis of the formulation "Sausages “Viennese with cheese”" TS 9213-010-40155161-2002 optimal price and quality alternative formulation. As a result of depreciation of the value of alternative stuffing recipe was 14,5 % when all of the restrictions on the consumer properties. The proposed information technology implemented in the software package "Multi

Quality control of radiopharmaceuticals

International Nuclear Information System (INIS)

Kristensen, K.

1981-01-01

Quality assurance was introduced in the pharmaceutical field long before it was used in many other areas, and the term quality control has been used in a much broader sense than merely analytical quality control. The term Good Manufacturing Practice (GMP) has been used to describe the system used for producing safe and effective drugs of a uniform quality. GMP has also been used for the industrial production of radiopharmaceuticals. For the preparation and control of radiopharmaceuticals in hospitals a similar system has been named Good Radiopharmacy Practice (GRP). It contains the same elements as GMP but takes into account the special nature of this group of drugs. Data on the assessment of the quality of radiopharmaceuticals in relation to present standards are reviewed. The general conclusion is that the quality of radiopharmaceuticals appears comparable to that of other drugs. It seems possible to establish the production of radiopharmaceuticals, generators and preparation kits in such a way that analytical control of the final product at the hospital may be limited provided the final preparation work is carried out in accordance with GRP principles. The elements of GRP are reviewed. (author)

Survey of product quality control of radioactive waste

International Nuclear Information System (INIS)

Warnecke, E.

1989-01-01

The PTB has developed basic procedures with regard to deriving final storage conditions and product quality control. After this, requirements for radioactive waste are derived via safety analysers, in which information about the radioactive waste, the geological overall situation of the site and the layout of the final storage mine, in particular, are included as basic data. The final storage conditions are only determined with the awarding of the planning decision. Compliance with them can be proved by random sample tests on waste containers or via a qualification and inspection of the conditioning process. (DG) [de

Production and quality control of 66 Ga as a PET radioisotope

International Nuclear Information System (INIS)

Rowshanfarzad, P.; Jalilian, A. R.; Akhlaghi, M.; Sabet, M.

2004-01-01

Background: 66 Ga (t 1/2 =9.49 h, β + : 4.153 MeV, γ: 511, 834, 1039, 2752 keV) has a wide range of applications in different fields of medical sciences. Production of 66 Ga became one of our main interests, according to its increasing applications in nuclear medicine, particularly in PET imaging. Materials and Methods: 66 Zn (p,n) 66 Ga reaction was determined as the best choice for the production of 66 Ga, according to the present facilities and conditions. The bombardment was performed by 15 MeV protons in Cyclone 30-IBA accelerator with a current intensity of 180 μA for 67 min. ALICE nuclear code and SRIM nuclear program were used to determine the optimum energy and target thickness. Targets were prepared by electroplating of 66 Zn (>95%) on a copper backing. Chemical processing was performed by a no carrier added method consisting of ion exchange chromatography and liquid-liquid extraction. Anion exchange chromatography was used for the recovery of target material. Quality control of the product was carried out in two steps of chemical and radionuclidic purity control. Results: the activity of 66 Ga was 2.41 Ci at the end of bombardment and the production yield was 12.04 mCi/μAh. The chemical separation yield was 93% and the yield of chemical recovery of the target material was 97%. Quality control tests showed a radionuclidic purity of more than 97% and the amounts of chemical impurities were in accordance with standard levels. Discussion: Our production yield was comparable with previous reports given in the literature. The chemical separation method used in this research was simple and brought up acceptable results. So, this process can be considered as one of the best choices for the production of 66 Ga

THE CONCEPTUAL FRAMEWORK OF FORMING THE PRODUCT QUALITY CONTROL STRATEGY OF ROAD-BUILDING ENGINEERING ENTERPRISES

Directory of Open Access Journals (Sweden)

Mariia Sadova

2017-11-01

Full Text Available The purpose of the work is the need of the theoretical justification and the development of relevant scientific and methodological approaches to the management of the road production quality of machine-building enterprises; it led to the choice of research topics. Methodology. Taking into account the value of existing methods of quality management of road production engineering companies, currently a particular attention requires improvement of the quality control functions: analysis, evaluation, planning and quality control during the operation of road-building equipment, because existing economic practices and quality management approaches are built on classical principles of ISO 9001, and in the practical application do not solve all of the drawbacks of traditional management models, but only smooth them a little. Therefore, the formation of the quality management strategy for the road production of mechanical engineering is essential to ensure the competitiveness of products and enterprises of the road-building complex in the period of development of market relations in the economy. The results showed that the current market conditions impose strict requirements to all production areas of the society. Especially stringent are requirements for the road construction, because the quality of the construction of the subgrade, covering roads and curbs, grading and soil compaction under different conditions of terrain and driving safety depends on people's lives. This factor determines the exceptional quality requirements for roadbuilding equipment, which must be reliable, functional and able to meet the totality of the design and operational characteristics of the road. Further European integration of Ukraine, deepening of external economic relations with the European countries are responsible for the growing needs of the national economy in the development and expansion of the transport network. However, large-scale road construction and repair

Quality control of radioactive waste products

International Nuclear Information System (INIS)

Martens, B.R.; Warnecke, E.; Odoj, R.

1986-01-01

The variety of incoming untreated wastes, treatment methods, waste forms and containers requires a great variety of controlling methods and principles to be applied both during waste treatment and on the final product. The paper describes product control schemes and methods, sampling systems and transportable testing equipment for waste drums, and equipment for waste cementation using in-drum stirring and subsequent fixation of solid wastes in the flowable product. (DG) [de

Expert database system for quality control

Science.gov (United States)

Wang, Anne J.; Li, Zhi-Cheng

1993-09-01

There are more competitors today. Markets are not homogeneous they are fragmented into increasingly focused niches requiring greater flexibility in the product mix shorter manufacturing production runs and above allhigher quality. In this paper the author identified a real-time expert system as a way to improve plantwide quality management. The quality control expert database system (QCEDS) by integrating knowledge of experts in operations quality management and computer systems use all information relevant to quality managementfacts as well as rulesto determine if a product meets quality standards. Keywords: expert system quality control data base

Applications of dimensional micro metrology to the product and process quality control in manufacturing of precision polymer micro components

DEFF Research Database (Denmark)

Tosello, Guido; Hansen, Hans Nørgaard; Gasparin, Stefania

2009-01-01

Precision manufacturing of micro injection moulded (mu IM) components presents challenges in terms of quality control due to the miniaturization of product dimensions and tolerances. This paper addresses product compliance with specifications, focusing on tolerances of dimensions and position on mu...... IM components selected from industrial production. Two systems were analysed: a tactile coordinate measuring machine (CMM) with sub-micrometer uncertainty and an optical CMM allowing fast measurements suitable for in-line quality control. Product quality control capability, measuring uncertainty...... and calibration guidelines are discussed for both systems. Finally, a new approach for the manufacturing of hybrid micro polymer-metal calibrated objects is proposed....

CAD/CAM: improved design quality, increased productivity

Energy Technology Data Exchange (ETDEWEB)

Evans, D. E.; England, J.

1980-01-01

Maintaining productivity levels while assuring the quality of engineering products grows increasingly more difficult and costly for industries such as the energy industry which are heavily committed to product design. The man/machine interface made possible through the development of computer-aided design/computer-aided manufacturing (CAD/CAM) technology can be applied to the design process as a tool for increased control to assure the quality of the final engineering product. The quality-control aspects of CAD/CAM technology are addressed in this presentation.

Measurement of the perceived quality of a product

Directory of Open Access Journals (Sweden)

Maire J.-L.

2013-01-01

Full Text Available For some companies, visual inspection has become an essential step when seeking to improve the quality of their products. The aim of this control is to be sure of the perceived quality of the product, which often goes well beyond the quality expected by the customer. For this type of control, the controller should be able to detect any anomaly on a product, characterize this anomaly, and then evaluate it in order to decide if the product should be accepted or rejected. This paper describes how this characterization can be carried out and, more specifically, how to measure the impact of the local environment of an anomaly on the perceived quality of the product.

Control cards as a statistical quality control resource

Directory of Open Access Journals (Sweden)

Aleksandar Živan Drenovac

2013-02-01

Full Text Available Normal 0 false false false MicrosoftInternetExplorer4 This paper proves that applying of statistical methods can significantly contribute increasing of products and services quality, as well as increasing of institutions rating. Determining of optimal, apropos anticipatory and limitary values, is based on sample`s statistical analyze. Control cards represent very confident instrument, which is simple for use and efficient for control of process, by which process is maintained in set borders. Thus, control cards can be applied in quality control of procesess of weapons and military equipment production, maintenance of technical systems, as well as for seting of standards and increasing of quality level for many other activities.

Quality assurance and product quality

International Nuclear Information System (INIS)

Lacroix, D.; Bastiani, P. de

2004-01-01

The basic quality assurance requirements have to be completed by means that are oriented towards the quality of products; in COGEMA LOGISTICS our approach is based on four principles: 1) an integrated management system: Quality, health and safety, environment 2) an organization based on the responsibility of all actors, trust and transparency 3) a methodical approach to continuously improve the methods that are employed to achieve quality: -process management -corrective and preventive actions -self assessments and various surveys 4) but at the same time strong procedures for control and monitoring of all activities: -technical and quality audits (external and internal) -at source inspections -engineering activities inspections This performance-based approach is necessary to guaranty the effectiveness of the traditional formal QA means

Product Quality and Worker Quality

OpenAIRE

Abowd, John M; Kramarz, Francis

1995-01-01

We study the relation between product quality and worker quality using an economic model that, under certain conditions, provides a direct link between product price, product quality and work-force quality. Our measures of product quality are the evolution in the detailed product price relative to its product group, and the level of the product price relative to this group. Our worker quality measures are the firm's average person effect and personal characteristics effect from individual wag...

Product Quality and Worker Quality

OpenAIRE

John M. ABOWD; Françis KRAMARZ; Antoine MOREAU

1996-01-01

We study the relation between product quality and worker quality using an economic model that, under certain conditions, provides a direct link between product price, product quality and work force quality. Our measures of product quality are the evolution in the detailed product price relative to its product group and the level of the product price relative to this group. Our worker quality measures are the firm's average person effect and personal characteristics effect from individual wage...

Porcelain Product Quality Analysis in PT XYZ

Directory of Open Access Journals (Sweden)

Ho Hwi Chie

2015-12-01

Full Text Available PT. XYZ is a company engaged in manufacturing porcelain dinner ware such as plates, cups, teapot, bowl, etc Porcelain product is safe for use and product defect will only affect the aesthetic not the functional side. The company always maintain the quality of the products produced as by maintaining a good product, in terms of visuals, will keep customers interested in the product. Good quality products characterized by quality A / B and C, and the product defect characterized by the quality of D, Lost, and BU. Concepts and methods used to analyze is a statistical process control (SPC which includes Pareto diagram, fraction nonconformities, flow charts and fishbone diagrams and management tools (fault tree analysis. Statistical Process Control (SPC is one of the methods, which includes Pareto charts, fraction nonconformities, flow chart, and fishbone diagram and also management tools (fault tree analysis. SPC is useful to find the facts from the problems and factors that affect the quality of the products, while fault tree analysis is useful to analyze each of the production process.

Production and quality control of concrete for the Rajasthan Atomic Power Station - [Part 2

International Nuclear Information System (INIS)

Singh Roy, P.K.; Sukhtankar, K.D.; Prasad, K.

1975-01-01

The following aspects of the production and quality control of concrete and concrete materials used in the construction of twin-reactor Rajasthan Atomic Power Station are discussed : (1) relationship between strength of cubes and cylinders made of concrete used for the prestressed dome (2) temperature control during pouring of concrete (3) thermal conductivity of heavy concrete (4) various types of grouting procedures used for different structures forming part of reactors (5) quality control of normal and heavy concrete and (6) leakage through form ties. Typical concrete mixes used for grouts are also given. (M.G.B.)

Product quality control, irradiation and shipping procedures for mass-reared tephritid fruit flies for sterile insect release programmes

International Nuclear Information System (INIS)

1999-05-01

This document represents the recommendations, reached by consensus of an international group of quality control experts, on the standard procedures for product quality control (QC) for mass reared tephritid flies that are to be used in Sterile Insect Technique (SIT) programs. In addition, the manual describes recommended methods of handling and packaging pupae during irradiation and shipment. Most of the procedures were designed specifically for use with Mediterranean fruit flies, Ceratitis capitata (Wied.), but they are applicable, with minor modification in some cases, for other tephritid species such as Caribbean fruit fly Anastrepha suspense, Mexican fruit fly A. ludens, and various Bactrocera species. The manual is evolving and subject to periodic updates. The future additions will include other fruit flies as the need is identified. If followed, procedures described in this manual will help ensure that the quality of mass-produced flies is measured accurately in a standardised fashion, allowing comparisons of quality over time and across rearing facilities and field programmes. Problems in rearing, irradiation and handling procedures, and strain quality can be identified and hopefully corrected before control programmes are affected. Tests and procedures described in this document are only part of a total quality control programme for tephritid fly production. The product QC evaluations included in this manual are, unless otherwise noted, required to be conducted during SIT programmes by the Field programme staff not the production staff. Additional product QC tests have been developed and their use is optional (see ancillary test section). Production and process QC evaluations (e.g., analysis of diet components, monitoring the rearing environment, yield of larvae, development rate, etc.) are not within the scope of this document. Quality specifications are included for minimum and mean acceptability of conventional strains of C. capitata, A. ludens, and A

Quality control of fifteen probiotic products containing Saccharomyces boulardii.

Science.gov (United States)

Vanhee, L M E; Goemé, F; Nelis, H J; Coenye, T

2010-11-01

The yeast Saccharomyces boulardii is used as a probiotic for the prevention and treatment of diarrhoea. In this study, the quality of 15 probiotic products containing S. boulardii was verified. Using microsatellite typing, the identity of all Saccharomyces strains in the products was confirmed as S. boulardii. Additionally, solid-phase cytometry (SPC) and a plate method were used to enumerate S. boulardii cells. SPC was not only able to produce results more rapidly than plating (4h compared to 48h) but the cell counts obtained with SPC were significantly higher than the plate counts. Finally, we found that boulardii cells survived 120min in gastric conditions and storage for 3months at 40°C with 75% relative humidity. We developed a SPC method for the quantification of viable S. boulardii cells in probiotics. Additionally, we demonstrated that gastric conditions and storage have a marked effect on the viability of the yeast cells.   To our knowledge, this is the first time SPC is used for the quality control of probiotics with S. boulardii. Additionally, we demonstrated the need for gastric protection and accurate storage. © 2010 The Authors. Journal of Applied Microbiology © 2010 The Society for Applied Microbiology.

Quality estimation methods used in product life cycle

OpenAIRE

M. Dudek-Burlikowska; D. Szewieczek

2007-01-01

Purpose: A new approach to quality control in production company with usage of quality research methods has been presented.Design/methodology/approach: The possibility of usage of quality research methods are connected with continuous quality improvement of pre-production, production and after-production spheres of organization. Interdependence of the quality research methods and product life cycle has been taken into account.Findings: At the present time the enterprises should integrate qua...

Control by quality: proposition of a typology.

Science.gov (United States)

Pujo, P; Pillet, M

The application of Quality tools and methods in industrial management has always had a fundamental impact on the control of production. It influences the behavior of the actors concerned, while introducing the necessary notions and formalizations, especially for production systems with little or no automation, which constitute a large part of the industrial activity. Several quality approaches are applied in the workshop and are implemented at the level of the control. In this paper, the authors present a typology of the various approaches that have successively influenced control, such as statistical process control, quality assurance, and continuous improvement. First the authors present a parallel between production control and quality organizational structure. They note the duality between control, which is aimed at increasing productivity, and quality, which aims to satisfy the needs of the customer. They also note the hierarchical organizational structure of these two systems of management with, at each level, the notion of a feedback loop. This notion is fundamental to any kind of decision making. The paper is organized around the operational, tactical, and strategic levels, by describing for each level the main methods and tools for control by quality. The overview of these tools and methods starts at the operational level, with the Statistical Process Control, the Taguchi technique, and the "six sigma" approach. On the tactical level, we find a quality system approach, with a documented description of the procedures introduced in the firm. The management system can refer here to Quality Assurance, Total Productive Maintenance, or Management by Total Quality. The formalization through procedures of the rules of decision governing the process control enhances the validity of these rules. This leads to the enhancement of their reliability and to their consolidation. All this counterbalances the human, intrinsically fluctuating, behavior of the control

Production and quality control of 65Zn radionuclide

International Nuclear Information System (INIS)

Rowshanfarzad, P.; Jalilian, R.; Sabet, M.

2005-01-01

Zinc-65 was produced in the Nuclear Research Center for Agriculture and Medicine (NRCAM) by the bombardment of natural copper targets with 30 MeV protons via the 65 Cu(p,n) 65 Zn nuclear reaction. Natural copper was used instead of enriched 65 Cu because of the quick decay of undesired radioisotopes. It was also more desirable for cost effectiveness. Cross-section calculations were performed by ALICE nuclear code and the results were compared with the experimental data given in the literature, which showed good agreement. A 160 μm copper layer target was bombarded with a 150 μA current of 30 MeV protons for 20 min, which resulted in 170 MBq activity of 65 Zn product. The yield was 3.4 MBq/μAh. The concentration of the product was 6.8 MBq/ml. Radiochemical separation was carried out by anion exchange chromatography with the yield of about 98%. Quality control of the final product showed a radionuclide purity of more than 98% and no traces of possible impurities (copper) were detected by a colorimetric method with a 1 ppm detection limit using dithizone as the reagent. The materials used for targetry and chemical separation were quite cost-effective. (author)

Application of Computer Vision for quality control in frozen mixed berries production: colour calibration issues

Directory of Open Access Journals (Sweden)

D. Ricauda Aimonino

2013-09-01

Full Text Available Computer vision is becoming increasingly important in quality control of many food processes. The appearance properties of food products (colour, texture, shape and size are, in fact, correlated with organoleptic characteristics and/or the presence of defects. Quality control based on image processing eliminates the subjectivity of human visual inspection, allowing rapid and non-destructive analysis. However, most food matrices show a wide variability in appearance features, therefore robust and customized image elaboration algorithms have to be implemented for each specific product. For this reason, quality control by visual inspection is still rather diffused in several food processes. The case study inspiring this paper concerns the production of frozen mixed berries. Once frozen, different kinds of berries are mixed together, in different amounts, according to a recipe. The correct quantity of each kind of fruit, within a certain tolerance, has to be ensured by producers. Quality control relies on bringing few samples for each production lot (samples of the same weight and, manually, counting the amount of each species. This operation is tedious, subject to errors, and time consuming, while a computer vision system (CVS could determine the amount of each kind of berries in a few seconds. This paper discusses the problem of colour calibration of the CVS used for frozen berries mixture evaluation. Images are acquired by a digital camera coupled with a dome lighting system, which gives a homogeneous illumination on the entire visible surface of the berries, and a flat bed scanner. RBG device dependent data are then mapped onto CIELab colorimetric colour space using different transformation operators. The obtained results show that the proposed calibration procedure leads to colour discrepancies comparable or even below the human eyes sensibility.

Quality Improvement and Learning in Productive Systems

OpenAIRE

Charles H. Fine

1986-01-01

Recent interest in product quality suggests that effort devoted to improving the quality of manufactured products may reduce unit costs. This conjecture---that improving quality can lower costs---challenges the traditional assumption that unit costs increase with increased quality assurance activities and has significant implications for quality management. By introducing the idea of a quality-based learning curve, this paper links the previously disjoint literatures of quality control and le...

Production and quality control of concrete for the Rajasthan Atomic Power Station - [Part 1

International Nuclear Information System (INIS)

Singha Roy, P.K.; Sukhtankar, K.D.; Prasad, K.

1975-01-01

The production and quality control of concrete and concrete materials for the construction of the twin-reactor Rajasthan Atomic Power Station with its 400 MW net capacity posed many challenges since many of the requirements for the properties of concrete were new and were being laid down for the first time in India. Some of the conditions for the concrete included leak-tightness against gas pressure, total absence of shrinkage in the containment even when the ambient temperature during concreting was as high as 45degC, placing concrete at a temperature as low as 8degC, the use of non-shrink and high strength grout, absolute impermeability against water, high density for radiation shielding, controlled modulus of elasticity for large machine foundations, high strength with high slump for the prestressed concrete dome, etc. Though the total quantity of concrete was not very much compared with a large river valley or steel plant project, (e.g., about 1.2 X 10 6 m 3 for a 2-million tonne steel plant) it was quite significant, being about 70,000 m 3 of normal density and 2,100 m 3 of high density concrete. The production of these quantities entailed intensive material study and investigation, development of new mixes with additives not tried out before in the country, and design and quality control techniques which were unique in many respects. The paper deals with the production and quality control of concrete, including grouts used in the projects, but the actual concreting and construction operations are not discussed. (author)

FUNGICIDES IN SECOND HARVEST CORN: CERCOSPORIOSE CONTROL AND BLOTCH, PRODUCTIVITY, ECONOMIC RETURN AND GRAIN QUALITY

Directory of Open Access Journals (Sweden)

P. Rezende

2017-10-01

Full Text Available Os objetivos desse trabalho foram avaliar a eficiência de The aim of this study was evaluate efficacy fungicides to control cercospora leaf spot (Cercospora zeae-maydis and helminthosporium leaf blight (Exserohilumturcicum, productivity, economic returns and quality of grain of corn culture of second crop in Farm Bandeirantes at Feliz Natal/MT. The treatments evaluated were: pyraclostrobina+epoxiconazol (0,7 L ha-1, trifloxistrobina+protioconazol (0,3L ha-1, azoxistrobina+cyproconazol(0,3 L ha-1, azoxystrobina (0,25 L ha-1, trifloxistrobina+ciproconazol (0,2 L ha-1 and control. Theapplicationof products occurred when corn was with 55 days, with a high propelled sprayer. The experimental design was a randomized block, with 6 treatments and 3 replications. The severity of each disease was visually determined through periodic analyses and ten plants were marked in each repetition, which were evaluated during the entire crop cycle. The data of severity obtained were used to calculate the area under disease progress curve (AUDPC. It was also obtained the production per ha, the economic return (R$ ha-1 and physiological quality of grain was evaluated by germination tests and accelerated aging of the grains. All treatments had significant difference compared to the control sample in controlling cercospora leaf spot about the control of helminthosporiumleat blight, the fungicides trifloxystrobin+prothioconazol and trifloxystrobin+cyproconazol were not efficient, and the fungicides pyraclostrobina+epoxiconazol, azoxystrobina, azoxistrobina+cyproconazol were efficient. The treatments that had major production are from the group of triazoles+strobilurine and the fungicide pyraclostrobin+epoxyconazol showed greater economic viability. Not were differences among fungicides, and neither of the treatments compared to control, in germination and accelerated aging tests, showing that the grains have good quality characteristics

Quality control and validation of the new IOP and GOP ocean products from CryoSat-2

Science.gov (United States)

Calafat, Francisco M.; Cipollini, Paolo; Snaith, Helen; Bouffard, Jérôme; Féménias, Pierre; Parrinello, Tommaso

2015-04-01

CryoSat-2 is a huge asset to the oceanographic community, and the exploitation of its data over the ocean represents a welcome additional return for ESA's investment in a mission whose primary objective is to monitor the cryosphere. The CryoSat Project has approved, in the frame of the CryoSat routine phase, the generation of additional ocean products which are available since April 2014. These are the Interim Ocean Products (IOP), normally available within 2-3 day from acquisition, and the Geophysical Ocean Products (GOP), with consolidated orbits and available 30 days after acquisition. To enable their full exploitation by the scientific and operational oceanographic communities, these new ocean products need to be thoroughly quality-controlled and validated. Here we present the results of the scientific quality control performed at the UK National Oceanography Centre (NOC) within the framework of the CryOcean-QCV project. The assessment and quality control of the data is conducted both daily and monthly on a global scale for the L2 IOP and GOP products and includes coverage/completeness, data flow and latency analysis, along-track and crossover analysis, and estimation of error levels and measurement precision. Diagnostics are computed for the sea surface height (SSH), significant wave height (SWH), radar backscatter coefficient (sigma0), wind speed and mispointing parameters. In addition we present an absolute validation of the altimetric SSH for the GOP product against sea level observations from high-quality tide gauges equipped with Global Positioning System (GPS) receivers. Finally, the validation is extended by comparing the SSH from CryoSat-2 with that from other altimetric missions (Envisat, Jason-1 and Jason-2).

Quality control of pesticide products

Energy Technology Data Exchange (ETDEWEB)

NONE

2009-07-15

In light of an established need for more efficient analytical procedures, this publication, which documents the findings of an IAEA coordinated research project (CRP) on “Quality Control of Pesticide Products”, simplifies the existing protocol for pesticide analysis while simultaneously upholding existing standards of quality. This publication includes both a report on the development work done in the CRP and a training manual for use by pesticide analysis laboratories. Based on peer reviewed and internationally recognized methods published by the Association of Analytical Communities (AOAC) and the Collaborative International Pesticides Analytical Council (CIPAC), this report provides laboratories with versatile tools to enhance the analysis of pesticide chemicals and to extend the scope of available analytical repertoires. Adoption of the proposed analytical methodologies promises to reduce laboratories’ use of solvents and the time spent on reconfiguration and set-up of analytical equipment.

Quality control of pesticide products

International Nuclear Information System (INIS)

2009-07-01

In light of an established need for more efficient analytical procedures, this publication, which documents the findings of an IAEA coordinated research project (CRP) on “Quality Control of Pesticide Products”, simplifies the existing protocol for pesticide analysis while simultaneously upholding existing standards of quality. This publication includes both a report on the development work done in the CRP and a training manual for use by pesticide analysis laboratories. Based on peer reviewed and internationally recognized methods published by the Association of Analytical Communities (AOAC) and the Collaborative International Pesticides Analytical Council (CIPAC), this report provides laboratories with versatile tools to enhance the analysis of pesticide chemicals and to extend the scope of available analytical repertoires. Adoption of the proposed analytical methodologies promises to reduce laboratories’ use of solvents and the time spent on reconfiguration and set-up of analytical equipment

33 CFR 385.21 - Quality control.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Quality control. 385.21 Section... Processes § 385.21 Quality control. (a) The Corps of Engineers and the non-Federal sponsor shall prepare a quality control plan, in accordance with applicable Corps of Engineers regulations, for each product that...

Radiopharmaceutical quality control-Pragmatic approach

International Nuclear Information System (INIS)

Barbier, Y.

1994-01-01

The quality control must be considered in a practical manner. The radiopharmaceuticals are drugs. They must satisfy the quality assurance control. These products are then conform to Pharmacopeia. But sometimes the user must control some data especially radiochemical purity and pH value. On all the administered solutions four controls are compulsory: radionuclide identity, administered radioactivity, organoleptic character and pH

Quality assurance and quality control

International Nuclear Information System (INIS)

Kaden, W.

1986-01-01

General preconditions and methods for QA work in the nuclear field are analysed. The application of general QA principles to actual situations is illustrated by examples in the fields of engineering and of the manufacturing of mechanical and electrical components. All QA measures must be fitted to the complexity and relevance of the work steps, which are under consideration. The key to good product quality is the control of working processes. The term 'controlled process' is discussed in detail and examples of feed back systems are given. The main QA measures for the operation of nuclear power plants include the establishment of a Quality Assurance Program, training and qualification of personnel, procurement control, inspection and tests, reviews and audits. These activities are discussed. (orig.)

7 CFR 58.928 - Quality control tests.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Quality control tests. 58.928 Section 58.928... Procedures § 58.928 Quality control tests. All dairy products and other ingredients shall be subject to inspection for quality and condition throughout each processing operation. Quality control tests shall be...

Quality control education in the community college

Science.gov (United States)

Greene, J. Griffen; Wilson, Steve

1966-01-01

This paper describes the Quality Control Program at Daytona Beach Junior College, including course descriptions. The program in quality control required communication between the college and the American Society for Quality Control (ASQC). The college has machinery established for certification of the learning process, and the society has the source of teachers who are competent in the technical field and who are the employers of the educational products. The associate degree for quality control does not have a fixed program, which can serve all needs, any more than all engineering degrees have identical programs. The main ideas which would be common to all quality control programs are the concept of economic control of a repetitive process and the concept of developing individual potentialities into individuals who are needed and productive.

7 CFR 58.335 - Quality control tests.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Quality control tests. 58.335 Section 58.335... Procedures § 58.335 Quality control tests. All milk, cream and related products are subject to inspection for quality and condition throughout each processing operation. Quality control tests shall be made on flow...

Quality control analysis at the hospital

International Nuclear Information System (INIS)

Kristensen, K.

1979-01-01

Quality control analysis is an integral part of quality assurance. In a system as with radiopharmaceuticals where part of the finishing of the product takes place at individual hospitals, the need for quality control analysis at the hospital can be discussed. Data are presented that stresses the importance of quality control by the manufacturer as a basis for limitation of such work at hospitals. A simplified programme is proposed

DEVELOPMENT AND APPLICATION OF THE KEY TECHNOLOGIES FOR THE QUALITY CONTROL AND INSPECTION OF NATIONAL GEOGRAPHICAL CONDITIONS SURVEY PRODUCTS

Directory of Open Access Journals (Sweden)

Y. Zhao

2018-04-01

Full Text Available The First National Geographical Condition Survey is a predecessor task to dynamically master basic situations of the nature, ecology and human activities on the earth’s surface and it is the brand-new mapping geographic information engineering. In order to ensure comprehensive, real and accurate survey results and achieve the quality management target which the qualified rate is 100 % and the yield is more than 80 %, it is necessary to carry out the quality control and result inspection for national geographical conditions survey on a national scale. To ensure that achievement quality meets quality target requirements, this paper develops the key technology method of “five-in-one” quality control that is constituted by “quality control system of national geographical condition survey, quality inspection technology system, quality evaluation system, quality inspection information management system and national linked quality control institutions” by aiming at large scale, wide coverage range, more undertaking units, more management levels, technical updating, more production process and obvious regional differences in the national geographical condition survey and combining with novel achievement manifestation, complicated dependency, more special reference data, and large data size. This project fully considering the domestic and foreign related research results and production practice experience, combined with the technology development and the needs of the production, it stipulates the inspection methods and technical requirements of each stage in the quality inspection of the geographical condition survey results, and extends the traditional inspection and acceptance technology, and solves the key technologies that are badly needed in the first national geographic survey.

Development and Application of the Key Technologies for the Quality Control and Inspection of National Geographical Conditions Survey Products

Science.gov (United States)

Zhao, Y.; Zhang, L.; Ma, W.; Zhang, P.; Zhao, T.

2018-04-01

The First National Geographical Condition Survey is a predecessor task to dynamically master basic situations of the nature, ecology and human activities on the earth's surface and it is the brand-new mapping geographic information engineering. In order to ensure comprehensive, real and accurate survey results and achieve the quality management target which the qualified rate is 100 % and the yield is more than 80 %, it is necessary to carry out the quality control and result inspection for national geographical conditions survey on a national scale. To ensure that achievement quality meets quality target requirements, this paper develops the key technology method of "five-in-one" quality control that is constituted by "quality control system of national geographical condition survey, quality inspection technology system, quality evaluation system, quality inspection information management system and national linked quality control institutions" by aiming at large scale, wide coverage range, more undertaking units, more management levels, technical updating, more production process and obvious regional differences in the national geographical condition survey and combining with novel achievement manifestation, complicated dependency, more special reference data, and large data size. This project fully considering the domestic and foreign related research results and production practice experience, combined with the technology development and the needs of the production, it stipulates the inspection methods and technical requirements of each stage in the quality inspection of the geographical condition survey results, and extends the traditional inspection and acceptance technology, and solves the key technologies that are badly needed in the first national geographic survey.

30 CFR 74.6 - Quality control.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Quality control. 74.6 Section 74.6 Mineral... of the CMDPSU will be maintained in production through adequate quality control procedures, MSHA and... DUST SAMPLING DEVICES Approval Requirements for Coal Mine Dust Personal Sampler Unit § 74.6 Quality...

Analysis of technology and quality control the fuel elements production process

International Nuclear Information System (INIS)

Katanic, J.; Spasic, Z.; Momcilovic, I.

1976-01-01

Recently great attention has been paid at the international level to the analysis of production processes and quality control of fuel elements with the aim to speed up activity of proposing and accepting standards and measurement methods. IAEA also devoted great interest to these problems appealing to more active participation of all users and procedures of fuel elements in a general effort to secure successful work with nuclear plants. For adequate and timely participation in future of the establishment and analysis of general requirements and documentation for the control of purchased or self produced fuel elements in our country, it is necessary to be well informed and to follow this activity at the international level

Role of configuration management in improving quality of metal products

International Nuclear Information System (INIS)

Ali, U.; Kalsoom, T.

2007-01-01

The Configuration Management (CM) is an imperative discipline which helps in producing quality metal products for the customers. CM implements a graded approach to Configuration Items whose failure poses human as well as product losses. Effective CM provides information to Project Management, Quality Control, and Quality Assurance in identifying schedules and processes related to metal component production. The CM is a supportive function, mostly working side by side with Quality Assurance and Quality Control in the development / production of metal parts. The CM provides tools and guidelines for managing a product while Quality Assurance verifies and validates the same outside the scope of Configuration Audits. Configuration Management raises productivity of metal product, makes-available design reuse, reduces service and support costs, enhances visibility and eliminates rework on metal products. The elements of CM i.e. Identification, Control, Status Accounting and Audits playa vital role to enhance the quality of metal products. Only established CM System can make it possible to swing initial development criteria to final user friendly metal products. The challenges of today in our metal industry are to design and develop state-of-the-art products, for which, CM ideas given in this paper, will help to achieve all the set goals. (author)

Concepts for modelling the quality of perishable products

NARCIS (Netherlands)

Sloof, M.; Tijskens, L.M.M.; Wilkinson, E.C.

1996-01-01

It is generally accepted that the quality of perishable products depends on three factors: the product, the user and the market situation. It is therefore difficult to define what quality is and how to control it. Decomposition of the effects of these factors on quality leads to a distinction

Radiation measurements and quality control

International Nuclear Information System (INIS)

McLaughlin, W.L.

1977-01-01

Accurate measurements are essential to research leading to a successful radiation process and to the commissioning of the process and the facility. On the other hand, once the process is in production, the importance to quality control of measuring radiation quantities (i.e., absorbed dose, dose rate, dose distribution) rather than various other parameters of the process (i.e. conveyor speed, dwell time, radiation field characteristics, product dimensions) is not clearly established. When the safety of the product is determined by the magnitude of the administered dose, as in radiation sterilization, waste control, or food preservation, accuracy and precision of the measurement of the effective dose are vital. Since physical dose measurements are usually simpler, more reliable and reproducible than biological testing of the product, there is a trend toward using standardized dosimetry for quality control of some processes. In many industrial products, however, such as vulcanized rubber, textiles, plastics, coatings, films, wire and cable, the effective dose can be controlled satisfactorily by controlling process variables or by product testing itself. In the measurement of radiation dose profiles by dosimetry, it is necessary to have suitable dose meter calibrations, to account for sources of error and imprecision, and to use correct statistical procedures in specifying dwell times or conveyor speeds and source and product parameters to achieve minimum and maximum doses within specifications. (author)

Quality by control: Towards model predictive control of mammalian cell culture bioprocesses.

Science.gov (United States)

Sommeregger, Wolfgang; Sissolak, Bernhard; Kandra, Kulwant; von Stosch, Moritz; Mayer, Martin; Striedner, Gerald

2017-07-01

The industrial production of complex biopharmaceuticals using recombinant mammalian cell lines is still mainly built on a quality by testing approach, which is represented by fixed process conditions and extensive testing of the end-product. In 2004 the FDA launched the process analytical technology initiative, aiming to guide the industry towards advanced process monitoring and better understanding of how critical process parameters affect the critical quality attributes. Implementation of process analytical technology into the bio-production process enables moving from the quality by testing to a more flexible quality by design approach. The application of advanced sensor systems in combination with mathematical modelling techniques offers enhanced process understanding, allows on-line prediction of critical quality attributes and subsequently real-time product quality control. In this review opportunities and unsolved issues on the road to a successful quality by design and dynamic control implementation are discussed. A major focus is directed on the preconditions for the application of model predictive control for mammalian cell culture bioprocesses. Design of experiments providing information about the process dynamics upon parameter change, dynamic process models, on-line process state predictions and powerful software environments seem to be a prerequisite for quality by control realization. © 2017 The Authors. Biotechnology Journal published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

21 CFR 820.70 - Production and process controls.

Science.gov (United States)

2010-04-01

...) MEDICAL DEVICES QUALITY SYSTEM REGULATION Production and Process Controls § 820.70 Production and process... used as part of production or the quality system, the manufacturer shall validate computer software for... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Production and process controls. 820.70 Section...

Validation of a liquid chromatographic method for the pharmaceutical quality control of products containing elacridar

Directory of Open Access Journals (Sweden)

Emilia Sawicki

2016-08-01

Full Text Available Many anticancer drugs have an impaired bioavailability and poor brain penetration because they are substrates to drug efflux pumps such as P-glycoprotein and Breast Cancer Resistance Protein. Elacridar is a strong inhibitor of these two drug efflux pumps and therefore has great potential to improve oral absorption and brain penetration of many anticancer drugs. Currently, a clinical formulation of elacridar is unavailable and therefore the pharmaceutical development of a drug product is highly warranted. This also necessitates the availability of an analytical method for its quality control. A reverse-phase high-performance liquid chromatographic method with ultraviolet detection was developed for the pharmaceutical quality control of products containing elacridar as the active pharmaceutical ingredient. The analytical method was validated for linearity, accuracy, precision, selectivity, carry-over, stability of stock and reference solutions, stability of the final extract, stability-indicating capability and impurity testing. We found that elacridar is unstable in aqueous solutions that are exposed to light because a hydroxylation product of elacridar is formed. Therefore, sample solutions with elacridar must be protected from light.

Quality control of CANDU6 fuel element in fabrication process

International Nuclear Information System (INIS)

Li Yinxie; Zhang Jie

2012-01-01

To enhance the fine control over all aspects of the production process, improve product quality, fuel element fabrication process for CANDU6 quality process control activities carried out by professional technical and management technology combined mode, the quality of the fuel elements formed around CANDU6 weak links - - end plug , and brazing processes and procedures associated with this aspect of strict control, in improving staff quality consciousness, strengthening equipment maintenance, improved tooling, fixtures, optimization process test, strengthen supervision, fine inspection operations, timely delivery carry out aspects of the quality of information and concerns the production environment, etc., to find the problem from the improvement of product quality and factors affecting the source, and resolved to form the active control, comprehensive and systematic analysis of the problem of the quality management concepts, effectively reducing the end plug weld microstructure after the failure times and number of defects zirconium alloys brazed, improved product quality, and created economic benefits expressly provided, while staff quality consciousness and attention to detail, collaboration department, communication has been greatly improved and achieved very good management effectiveness. (authors)

Production And Quality Control Of Radiopharmaceutical 18F-FDG

International Nuclear Information System (INIS)

Dinh Thi Bich Lieu; Nguyen Van Si; Vu Van Tien

2011-01-01

18 F-FDG is a radiopharmaceutical for imaging diagnosis with PET/CT in Nuclear Medicine. Criteria of injection pharmaceuticals are the highest standards. So, quality assurance and quality control must be followed very strictly. The selection of the procedure for 18 F-FDG has based on several criteria: high chemical efficiency, short synthesis time, toxic component free and etc. The quality control of 18 F-FDG consist many fields such as: nuclear physic (nuclear purity), radiochemistry (radionuclear purity, radiochemical purity), chemistry (chemical purity), radiation measurement (half life), microbiology (pyrogen, endotoxin), etc. which is following USP, BP or EP. (author)

Deficiencies in product labelling instructions and quality control directions for 99mTc radiopharmaceuticals.

Science.gov (United States)

Buroni, Federica E; Lodola, Lorenzo; Persico, Marco G; Aprile, Carlo

2014-02-01

The aim of the study was to identify deficiencies in product labelling instructions for reconstitution and in the quality control directions detailed in the technical leaflets (TLs) or summary product characteristic (SPC) sheets of commonly used technetium labelling cold kits. The reconstitution and quality control directions in 25 TLs/SPCs were evaluated to identify deficiencies, incompleteness, restrictions, errors, impracticability, and vagueness. In addition, their congruence with the statements given in the relative European Pharmacopoeia (Ph. Eur. VII ed.) monography and diagnostic reference levels of Directive 97/43/EURATOM was evaluated. Deficiencies in information were scored and classified into five categories: 1, absent or incomplete; 2, restrictive; 3, inconsistent or wrong; 4, impractical; and 5, vague. In the 25 documents analyzed a total of 141 deficiencies were found (corresponding to 40.2% of the total scores assigned), and more frequently they pertained to quality control procedures (70.9%), followed by those related to quantitative composition (14.9%), preparation (8.5%), and particle size (5.7%). Nearly 80% of these deficiencies were classified as type 1 - that is, absent or incomplete information. The indications in TLs and SPCs should provide useful information for maintaining the quality and purity of the radiopharmaceutical preparation and ensure the safety level and effectiveness required by law. However, the instructions are often suboptimal or even erroneous, and consequently there are countless failures or difficulties, which represent an impediment to good laboratory practice. We believe that a 'smart' review of radiopharmaceutical documentation would be beneficial in order to align these indications to the real needs of the operators involved in routine in-house nuclear medicine practice.

Radioscopy applied to the improvement of industrial processes of quality control in the Brazilian footwear production

Energy Technology Data Exchange (ETDEWEB)

Fernandes, Marcela Tatiana Fernandes; Mello Filho, Mauro Otto de Cavalcanti, E-mail: mbeserra@cefet-rj.br, E-mail: maurootto@cefet-rj.br [Centro Federal de Educacao Tecnologica Celso Suckow da Fonseca (CEFET-RJ), Rio de Janeiro, RJ (Brazil); Raupp, Fernanda Maria Pereira, E-mail: fraupp@puc-rio.br [Pontificia Universidade Catolica do Rio de Janeiro (PUC-Rio), Rio de Janeiro, RJ (Brazil). Departamento de Engenharia Industrial

2013-07-01

According to the Ministry of Development, Industry and Foreign Trade, China has the last five years in the Brazilian footwear market for imports, representing 70% of total imports. Brazil has been recording declines in footwear exports; in 2011 there was an average reduction of 21.5% compared to 2010. Thus, Brazil has moved to the eighth position in the export market. Moreover, Asians have been improving the quality and technological level of their footwear for niche markets. It is well known that the introduction of new technologies into industrial organizations enables adding value to their products, making the organizations more competitive in the global market. In this work, we present a study on the use of radioscopy technique to improve quality control of the Brazilian footwear industry. Being already used by some international footwear manufactures, aiming at the identification of strange bodies, control jumps, among other aspects, this technique brings innovation to the referred industry, since it is a non-destructive test approach that makes use of X-rays. We also propose a tool for the application of radioscopy technique to improve quality control processes of footwear production, employing concepts of Failure Modes and Effects Analysis (FMEA). (author)

Radioscopy applied to the improvement of industrial processes of quality control in the Brazilian footwear production

International Nuclear Information System (INIS)

Fernandes, Marcela Tatiana Fernandes; Mello Filho, Mauro Otto de Cavalcanti; Raupp, Fernanda Maria Pereira

2013-01-01

According to the Ministry of Development, Industry and Foreign Trade, China has the last five years in the Brazilian footwear market for imports, representing 70% of total imports. Brazil has been recording declines in footwear exports; in 2011 there was an average reduction of 21.5% compared to 2010. Thus, Brazil has moved to the eighth position in the export market. Moreover, Asians have been improving the quality and technological level of their footwear for niche markets. It is well known that the introduction of new technologies into industrial organizations enables adding value to their products, making the organizations more competitive in the global market. In this work, we present a study on the use of radioscopy technique to improve quality control of the Brazilian footwear industry. Being already used by some international footwear manufactures, aiming at the identification of strange bodies, control jumps, among other aspects, this technique brings innovation to the referred industry, since it is a non-destructive test approach that makes use of X-rays. We also propose a tool for the application of radioscopy technique to improve quality control processes of footwear production, employing concepts of Failure Modes and Effects Analysis (FMEA). (author)

Problems of quality assurance and quality control in diagnostic radiology

International Nuclear Information System (INIS)

Angerstein, W.

1986-01-01

Topical problems of quality assurance and quality control in diagnostic radiology are discussed and possible solutions are shown. Complex units are differentiated with reference to physicians, technicians, organization of labour, methods of examination and indication. Quality control of radiologic imaging systems should involve three stages: (1) simple tests carried out by radiologic technicians, (2) measurements by service technicians, (3) testing of products by the manufacturer and independent governmental or health service test agencies. (author)

[Quality control in herbal supplements].

Science.gov (United States)

Oelker, Luisa

2005-01-01

Quality and safety of food and herbal supplements are the result of a whole of different elements as good manufacturing practice and process control. The process control must be active and able to individuate and correct all possible hazards. The main and most utilized instrument is the hazard analysis critical control point (HACCP) system the correct application of which can guarantee the safety of the product. Herbal supplements need, in addition to standard quality control, a set of checks to assure the harmlessness and safety of the plants used.

Quality control and quality assurance in individual monitoring of ionising radiations

International Nuclear Information System (INIS)

Dutt, J.C.; Lindborg, L.

1994-01-01

This paper describes the programmes and approaches that are to be considered in developing and introducing quality assurance and quality control procedures in individual monitoring services. Quality assurance and quality control in individual monitoring services are essential to maintain quality and are of increasing importance in order to meet the requirements of national regulations and international standards and guidelines. It is recommended here that all organisations offering individual monitoring services should run their services based on the principles of Quality System as given in the European Standard EN45001 and maintain a property resources QA/QC programme as an integral part of their operations. All aspects of QA/QC in individual monitoring services starting from the initial selection, installation, calibration, and operation to the final products including dose reporting, dose record keeping, dealing with customers' complaints and product liability issues have been discussed. (Author)

Quality Assurance/Quality Control Jobs

Science.gov (United States)

Fanslau, Melody; Young, Janelle

The production of a quality and safe food product is essential to the success of any food manufacturing facility. Because of this great importance, a career in quality can be extremely rewarding. Without happy customers willing to buy a product, a company would not be able to survive. Quality issues such as foreign objects, spoiled or mislabeled product, failure to meet net weight requirements, or a recall can all turn customers away from buying a product. The food industry is a customer-driven market in which some consumers are brand loyal based on a history of high quality or in which a single bad experience with a product will turn them away for a lifetime. With this said, the main role of a quality department is to help ensure that quality issues such as these are eliminated or kept to a minimum to maintain or increase the number of customers purchasing their product.

Software product quality measurement

OpenAIRE

Godliauskas, Eimantas

2016-01-01

This paper analyses Ruby product quality measures, suggesting three new measures for Ruby product quality measurement tool Rubocop to measure Ruby product quality characteristics defined in ISO 2502n standard series. This paper consists of four main chapters. The first chapter gives a brief view of software product quality and software product quality measurement. The second chapter analyses object oriented quality measures. The third chapter gives a brief view of the most popular Ruby qualit...

Net analyte signal based statistical quality control

NARCIS (Netherlands)

Skibsted, E.T.S.; Boelens, H.F.M.; Westerhuis, J.A.; Smilde, A.K.; Broad, N.W.; Rees, D.R.; Witte, D.T.

2005-01-01

Net analyte signal statistical quality control (NAS-SQC) is a new methodology to perform multivariate product quality monitoring based on the net analyte signal approach. The main advantage of NAS-SQC is that the systematic variation in the product due to the analyte (or property) of interest is

21 CFR 111.105 - What must quality control personnel do?

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What must quality control personnel do? 111.105..., LABELING, OR HOLDING OPERATIONS FOR DIETARY SUPPLEMENTS Production and Process Control System: Requirements for Quality Control § 111.105 What must quality control personnel do? Quality control personnel must...

Water quality control system and water quality control method

International Nuclear Information System (INIS)

Itsumi, Sachio; Ichikawa, Nagayoshi; Uruma, Hiroshi; Yamada, Kazuya; Seki, Shuji

1998-01-01

In the water quality control system of the present invention, portions in contact with water comprise a metal material having a controlled content of iron or chromium, and the chromium content on the surface is increased than that of mother material in a state where compression stresses remain on the surface by mechanical polishing to form an uniform corrosion resistant coating film. In addition, equipments and/or pipelines to which a material controlling corrosion potential stably is applied on the surface are used. There are disposed a cleaning device made of a material less forming impurities, and detecting intrusion of impurities and removing them selectively depending on chemical species and/or a cleaning device for recovering drain from various kinds of equipment to feedwater, connecting a feedwater pipeline and a condensate pipeline and removing impurities and corrosion products. Then, water can be kept to neutral purified water, and the concentrations of oxygen and hydrogen in water are controlled within an optimum range to suppress occurrence of corrosion products. (N.H.)

VGI QUALITY CONTROL

Directory of Open Access Journals (Sweden)

C. C. Fonte

2015-08-01

Full Text Available This paper presents a framework for considering quality control of volunteered geographic information (VGI. Different issues need to be considered during the conception, acquisition and post-acquisition phases of VGI creation. This includes items such as collecting metadata on the volunteer, providing suitable training, giving corrective feedback during the mapping process and use of control data, among others. Two examples of VGI data collection are then considered with respect to this quality control framework, i.e. VGI data collection by National Mapping Agencies and by the most recent Geo-Wiki tool, a game called Cropland Capture. Although good practices are beginning to emerge, there is still the need for the development and sharing of best practice, especially if VGI is to be integrated with authoritative map products or used for calibration and/or validation of land cover in the future.

Application of Six Sigma Using DMAIC Methodology in the Process of Product Quality Control in Metallurgical Operation

Directory of Open Access Journals (Sweden)

Girmanová Lenka

2017-12-01

Full Text Available The Six Sigma DMAIC can be considered a guide for problem solving and product or process improvement. The majority of companies start to implement Six Sigma using the DMAIC methodology. The paper deals with application of Six Sigma using the DMAIC methodology in the process of product quality control. The case study is oriented on the field of metallurgical operations. The goal of the Six Sigma project was to ensure the required metallurgic product quality and to avoid an increase in internal costs associated with poor product quality. In this case study, a variety of tools and techniques like flow chart, histogram, Pareto diagram, analysis of FMEA (Failure Mode and Effect Analysis data, cause and effect diagram, logical analysis was used. The Sigma level has improved by approximately 13%. The achieved improvements have helped to reduce the quantity of defective products and the processing costs (technology for re-adjusting. Benefits resulting from the DMAIC implementation can be divided into three levels: the qualitative, economic and safety level.

Growth of optical-quality anthracene crystals doped with dibenzoterrylene for controlled single photon production

Energy Technology Data Exchange (ETDEWEB)

Major, Kyle D., E-mail: kyle.major11@imperial.ac.uk; Lien, Yu-Hung; Polisseni, Claudio; Grandi, Samuele; Kho, Kiang Wei; Clark, Alex S.; Hwang, J.; Hinds, E. A., E-mail: ed.hinds@imperial.ac.uk [Centre for Cold Matter, Department of Physics, Blackett Laboratory, Imperial College London, Prince Consort Road, London SW7 2AZ (United Kingdom)

2015-08-15

Dibenzoterrylene (DBT) molecules within a crystalline anthracene matrix show promise as quantum emitters for controlled, single photon production. We present the design and construction of a chamber in which we reproducibly grow doped anthracene crystals of optical quality that are several mm across and a few μm thick. We demonstrate control of the DBT concentration over the range 6–300 parts per trillion and show that these DBT molecules are stable single-photon emitters. We interpret our data with a simple model that provides some information on the vapour pressure of DBT.

Quality management manual for production of high quality cassava flour

DEFF Research Database (Denmark)

Dziedzoave, Nanam Tay; Abass, Adebayo Busura; Amoa-Awua, Wisdom K.

The high quality cassava flour (HQCF) industry has just started to evolve in Africa and elsewhere. The sustainability of the growing industry, the profitability of small- and medium-scale enterprises (SMEs) that are active in the industry and good-health of consumers can best be guaranteed through...... the adoption of proper quality and food safety procedures. Cassava processing enterprises involved in the productionof HQCF must therefore be commited to the quality and food safety of the HQCF. They must have the right technology, appropriate processing machhinery, standard testing instruments...... and the necessary technical expertise. This quality manual was therefore developed to guide small- to medium-scale cassava in the design and implematation of Hazard Analysis Critical Control Point (HACCP) system and Good manufacturing Practices (GMP) plans for HQCF production. It describes the HQCF production...

Efficiency of the functioning of the state control system for the safety and quality of animal products in Ukraine

Directory of Open Access Journals (Sweden)

I. Kyryliuk

2017-12-01

Full Text Available The study reveals the results of evaluating the effectiveness of the state control system (supervision on the safety and individual indicators of the quality of livestock products in Ukraine. The necessity of application of such components of efficiency as legislation, management and its organizational structure, inspection and laboratory service, information, training and communications is substantiated. It has been determined that during a sufficiently long period of time (until 2015, the system of state control (supervision was archaic and actually focused on the principles of command and administrative economy. The modern tendencies and specifics of the improvement of the Ukrainian control system in the direction of its harmonization with the European one are shown. The emphasis was on significant volumes of work that needed to be done in a very short time, as well as in the absence of adequate funding and appropriate skilled specialists. The emergence of clarity and unambiguousness in determining the responsibility of market operators for violating the legislation requirements in the field of production and circulation of animal origin food products was emphasized. Along with the achievements, there were identified systemic problems related to the technical regulation of safety assurance processes and individual quality indicators in Ukraine. Also it was noted and revealed that legislation in the area of guaranteeing the quality and safety of livestock products in Ukraine remains incomplete and not fully developed. The necessity of development of a number of by-laws and allocation of necessary financing for effective functioning of the state control system over product safety is substantiated. Article specified on the presence of insufficient number of professional inspection and laboratory services is underlined. The mechanisms of avoiding corruption risks and excessive pressure on the subjects of the livestock production market are

14 CFR 21.147 - Changes in quality control system.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Changes in quality control system. 21.147 Section 21.147 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... quality control system. After the issue of a production certificate, each change to the quality control...

Quality assurance in education: The role of ICT and quality control ...

African Journals Online (AJOL)

Quality assurance in education is perceived in this paper to be a product of the impact of information and communication technologies as well as the statutory control measures especially in tertiary institutions in Nigeria. The paper reviews the concept of quality and quality assurance and their general application to ...

Quality assurance and quality control in fabrication of heat exchanger tubes

International Nuclear Information System (INIS)

Duennewald, A.

1980-01-01

Object of this report is the manufacture of heat exchanger tubes. A comprehensive manufacturing and test program has to be established to assure and prove and equal tube quality. This requires a functionally operating quality assurance system combined with a production exactly planned in advance. A specific continuous production line for heat exchanger tubes has been erected at the Hellenthal plant of the Mannesmannroehren-Werke. All production steps and heat treatments are generally controlled by a quality control department. Non-destructive testing of each tube produced in standard length is performed on several agregates in line using ultrasonic and/or eddy current technique. All tests are generally performed in the presence of quality inspectors or surveyors. For a lot of heat exchangers the straight tubes have to be hairpin bended. To avoid the risk of stress corrosion cracking, it is recommended to procreate defined compression stresses in the outside tube surface. Prior to releasing the tubes to shipment, the completeness of the documentation as to the manufacturing steps and inspection agreed upon is thoroughly checked. (RW)

Quality assurance/quality control, reliability and availability of nuclear power plants

International Nuclear Information System (INIS)

Kueffer, K.

1981-01-01

In a first part this lectures will present a survey on nuclear power production and plant performance in the Western World and discuss key parameters such as load factors and non-availability. Some main reasons for reliable performance of nuclear power plants are given. The second part of this lecture deals with the question how quality assurance and quality control measures do directly influence plant reliability, availability and, thus, economy. Derived from worldwide experience gained from operating nuclear power plants, it may be concluded that the implementation of an overall quality assurance programme does not only satisfy safety requirements set forth by the nuclear regulatory bodies, but has also a considerable impact on plant reliability and availability. A positive effect on these figures will be achieved if the established quality assurance programme provides for a coordinated approach to all activities affecting quality. It is discussed how the quality of a product should be controlled and what kind of quality assurance measures by performed examples are given to demonstrate that the expenditure for maintenance work on components will decrease if planned and systematic quality assurance actions have been implemented during all procurement stages. (orig./RW)

Fuel cycle and quality control

International Nuclear Information System (INIS)

Stoll, W.

1979-01-01

The volume of the fuel cycle is described in its economic importance and its through put, as it is envisaged for the Federal Republic of Germany. Definitions are given for quality continuing usefulness of an object and translated into quality criteria. Requirements on performance of fuel elements are defined. The way in which experimental results are translated into mass production of fuel rods, is described. The economic potential for further quality effort is derived. Future ways of development for quality control organisation and structure are outlined. (Auth.)

Pharmaceutical product development: A quality by design approach

Science.gov (United States)

Pramod, Kannissery; Tahir, M. Abu; Charoo, Naseem A.; Ansari, Shahid H.; Ali, Javed

2016-01-01

The application of quality by design (QbD) in pharmaceutical product development is now a thrust area for the regulatory authorities and the pharmaceutical industry. International Conference on Harmonization and United States Food and Drug Administration (USFDA) emphasized the principles and applications of QbD in pharmaceutical development in their guidance for the industry. QbD attributes are addressed in question-based review, developed by USFDA for chemistry, manufacturing, and controls section of abbreviated new drug applications. QbD principles, when implemented, lead to a successful product development, subsequent prompt regulatory approval, reduce exhaustive validation burden, and significantly reduce post-approval changes. The key elements of QbD viz., target product quality profile, critical quality attributes, risk assessments, design space, control strategy, product lifecycle management, and continual improvement are discussed to understand the performance of dosage forms within design space. Design of experiments, risk assessment tools, and process analytical technology are also discussed for their role in QbD. This review underlines the importance of QbD in inculcating science-based approach in pharmaceutical product development. PMID:27606256

Pharmaceutical product development: A quality by design approach.

Science.gov (United States)

Pramod, Kannissery; Tahir, M Abu; Charoo, Naseem A; Ansari, Shahid H; Ali, Javed

2016-01-01

The application of quality by design (QbD) in pharmaceutical product development is now a thrust area for the regulatory authorities and the pharmaceutical industry. International Conference on Harmonization and United States Food and Drug Administration (USFDA) emphasized the principles and applications of QbD in pharmaceutical development in their guidance for the industry. QbD attributes are addressed in question-based review, developed by USFDA for chemistry, manufacturing, and controls section of abbreviated new drug applications. QbD principles, when implemented, lead to a successful product development, subsequent prompt regulatory approval, reduce exhaustive validation burden, and significantly reduce post-approval changes. The key elements of QbD viz., target product quality profile, critical quality attributes, risk assessments, design space, control strategy, product lifecycle management, and continual improvement are discussed to understand the performance of dosage forms within design space. Design of experiments, risk assessment tools, and process analytical technology are also discussed for their role in QbD. This review underlines the importance of QbD in inculcating science-based approach in pharmaceutical product development.

Determination of the Reliability of Product Quality Loss and Control ...

African Journals Online (AJOL)

Product quality loss was determined to be 22. However, the X-chart was found to be the most suitable and effective. The values indicate that by using the X-chart model, about 96.4% of the suspected defective products would actually survive standard tests. This model has successfully eliminated the number of the proposed ...

21 CFR 640.56 - Quality control test for potency.

Science.gov (United States)

2010-04-01

... quality control test for potency may be performed by a clinical laboratory which meets the standards of... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Quality control test for potency. 640.56 Section...) BIOLOGICS ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Cryoprecipitate § 640.56 Quality control...

Seven Basic Tools of Quality Control: An Appropriate Tools for Solving Quality Problems in the Organizations

OpenAIRE

Neyestani, Behnam

2017-01-01

Dr. Kaoru Ishikawa was first total quality management guru, who has been associated with the development and advocacy of using the seven quality control (QC) tools in the organizations for problem solving and process improvements. Seven old quality control tools are a set of the QC tools that can be used for improving the performance of the production processes, from the first step of producing a product or service to the last stage of production. So, the general purpose of this paper was to...

Quality Control - Nike.Inc

OpenAIRE

Walter G. Bishop

2017-01-01

The purpose of this paper is to present the illustration of quality control approach, which has been adopted by several organizations, in order to manage and improve their production processes. The approach is referred as total quality management (TQM). This study will discuss the implementation of TQ, within the working environment of Nike Inc. One of the major objectives behind the implementation of TQ is to reduce or completely eliminate potential errors and flaws, within the manufacturing...

USE OF INTELLECTUAL TECHNOLOGIES FOR QUALITY CONTROL OF CURD

Directory of Open Access Journals (Sweden)

M. M. Blagoveshchenskaya

2015-01-01

Full Text Available In this article, we consider additional method of quality control of curds by organoleptic properties. Method consists in construction of neural network model to estimate quality of curds by input and output parameters. Quality control of curds by organoleptic properties is not necessary according to state standard specification, therefore we use exemplary 5-score scale for organoleptic estimation. Author gives an example of fundamental operation which is necessary for neural networks projection and gives recommendation for integrated hardware/software solution design. This method makes easier quality control of final product because operator can react on digression in the technological process in proper time (use data recommended by neural network, predict quality of final product in case when technological parameters deviate from the norm.

Image processing system performance prediction and product quality evaluation

Science.gov (United States)

Stein, E. K.; Hammill, H. B. (Principal Investigator)

1976-01-01

The author has identified the following significant results. A new technique for image processing system performance prediction and product quality evaluation was developed. It was entirely objective, quantitative, and general, and should prove useful in system design and quality control. The technique and its application to determination of quality control procedures for the Earth Resources Technology Satellite NASA Data Processing Facility are described.

Design and implementation of a control structure for quality products in a crude oil atmospheric distillation column.

Science.gov (United States)

Sotelo, David; Favela-Contreras, Antonio; Sotelo, Carlos; Jiménez, Guillermo; Gallegos-Canales, Luis

2017-11-01

In recent years, interest for petrochemical processes has been increasing, especially in refinement area. However, the high variability in the dynamic characteristics present in the atmospheric distillation column poses a challenge to obtain quality products. To improve distillates quality in spite of the changes in the input crude oil composition, this paper details a new design of a control strategy in a conventional crude oil distillation plant defined using formal interaction analysis tools. The process dynamic and its control are simulated on Aspen HYSYS ® dynamic environment under real operating conditions. The simulation results are compared against a typical control strategy commonly used in crude oil atmospheric distillation columns. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.

standards used for quality control of nuclear fuels

International Nuclear Information System (INIS)

Guereli, L; Can, S.

1997-01-01

Nuclear fuels and fuel materials are subject to stringent restrictions as to their quality. The standards and regulations that apply vary according to reactor type and country and the standards are stated in the quality assurance documents. The concept of quality assurance has altered the conventional quality control tests and procedures, defining which control tests are to be applied and how. Although most of the tests and measurements allow the determination of tolerances to be decided according to the agreement between the buyer and the seller, exacting procedures apply to which instruments and equipment are used for these tests and measurements, how these instruments are standardized.Detailed explanations of test methods and their documentation is a requirement in all standards. The purpose of this work is to study which standards, tests and measurements apply to the nuclear fuel production. Only the standards that apply to various stages of the nuclear fuel production (powder preparation, pellet production, fuel element and fuel assembly fabrication) are reviewed. Process and documentation control, design and licensing requirements and the frequency of inspections are quality assurance subjects. Some ASTM standards are given as examples

Developing methods of controlling quality costs

Directory of Open Access Journals (Sweden)

Gorbunova A. V.

2017-01-01

Full Text Available The article examines issues of managing quality costs, problems of applying economic methods of quality control, implementation of progressive methods of quality costs management in enterprises with the view of improving the efficiency of their evaluation and analysis. With the aim of increasing the effectiveness of the cost management mechanism, authors introduce controlling as a tool of deviation analysis from the standpoint of the process approach. A list of processes and corresponding evaluation criteria in the quality management system of enterprises is introduced. Authors also introduce the method of controlling quality costs and propose it for the practical application, which allows them to determine useful and unnecessary costs at the existing operating plant. Implementing the proposed recommendations in the system of cost management at an enterprise will allow to improve productivity of processes operating and reduce wasted expense on the quality of the process on the basis of determining values of useful and useless costs of quality according to criteria of processes functioning in the system of quality management.

Process performance and product quality in an integrated continuous antibody production process.

Science.gov (United States)

Karst, Daniel J; Steinebach, Fabian; Soos, Miroslav; Morbidelli, Massimo

2017-02-01

Continuous manufacturing is currently being seriously considered in the biopharmaceutical industry as the possible new paradigm for producing therapeutic proteins, due to production cost and product quality related benefits. In this study, a monoclonal antibody producing CHO cell line was cultured in perfusion mode and connected to a continuous affinity capture step. The reliable and stable integration of the two systems was enabled by suitable control loops, regulating the continuous volumetric flow and adapting the operating conditions of the capture process. For the latter, an at-line HPLC measurement of the harvest concentration subsequent to the bioreactor was combined with a mechanistic model of the capture chromatographic unit. Thereby, optimal buffer consumption and productivity throughout the process was realized while always maintaining a yield above the target value of 99%. Stable operation was achieved at three consecutive viable cell density set points (20, 60, and 40 × 10 6 cells/mL), together with consistent product quality in terms of aggregates, fragments, charge isoforms, and N-linked glycosylation. In addition, different values for these product quality attributes such as N-linked glycosylation, charge variants, and aggregate content were measured at the different steady states. As expected, the amount of released DNA and HCP was significantly reduced by the capture step for all considered upstream operating conditions. This study is exemplary for the potential of enhancing product quality control and modulation by integrated continuous manufacturing. Biotechnol. Bioeng. 2017;114: 298-307. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Implementation of Cyber-Physical Production Systems for Quality Prediction and Operation Control in Metal Casting.

Science.gov (United States)

Lee, JuneHyuck; Noh, Sang Do; Kim, Hyun-Jung; Kang, Yong-Shin

2018-05-04

The prediction of internal defects of metal casting immediately after the casting process saves unnecessary time and money by reducing the amount of inputs into the next stage, such as the machining process, and enables flexible scheduling. Cyber-physical production systems (CPPS) perfectly fulfill the aforementioned requirements. This study deals with the implementation of CPPS in a real factory to predict the quality of metal casting and operation control. First, a CPPS architecture framework for quality prediction and operation control in metal-casting production was designed. The framework describes collaboration among internet of things (IoT), artificial intelligence, simulations, manufacturing execution systems, and advanced planning and scheduling systems. Subsequently, the implementation of the CPPS in actual plants is described. Temperature is a major factor that affects casting quality, and thus, temperature sensors and IoT communication devices were attached to casting machines. The well-known NoSQL database, HBase and the high-speed processing/analysis tool, Spark, are used for IoT repository and data pre-processing, respectively. Many machine learning algorithms such as decision tree, random forest, artificial neural network, and support vector machine were used for quality prediction and compared with R software. Finally, the operation of the entire system is demonstrated through a CPPS dashboard. In an era in which most CPPS-related studies are conducted on high-level abstract models, this study describes more specific architectural frameworks, use cases, usable software, and analytical methodologies. In addition, this study verifies the usefulness of CPPS by estimating quantitative effects. This is expected to contribute to the proliferation of CPPS in the industry.

Implementation of Cyber-Physical Production Systems for Quality Prediction and Operation Control in Metal Casting

Directory of Open Access Journals (Sweden)

JuneHyuck Lee

2018-05-01

Full Text Available The prediction of internal defects of metal casting immediately after the casting process saves unnecessary time and money by reducing the amount of inputs into the next stage, such as the machining process, and enables flexible scheduling. Cyber-physical production systems (CPPS perfectly fulfill the aforementioned requirements. This study deals with the implementation of CPPS in a real factory to predict the quality of metal casting and operation control. First, a CPPS architecture framework for quality prediction and operation control in metal-casting production was designed. The framework describes collaboration among internet of things (IoT, artificial intelligence, simulations, manufacturing execution systems, and advanced planning and scheduling systems. Subsequently, the implementation of the CPPS in actual plants is described. Temperature is a major factor that affects casting quality, and thus, temperature sensors and IoT communication devices were attached to casting machines. The well-known NoSQL database, HBase and the high-speed processing/analysis tool, Spark, are used for IoT repository and data pre-processing, respectively. Many machine learning algorithms such as decision tree, random forest, artificial neural network, and support vector machine were used for quality prediction and compared with R software. Finally, the operation of the entire system is demonstrated through a CPPS dashboard. In an era in which most CPPS-related studies are conducted on high-level abstract models, this study describes more specific architectural frameworks, use cases, usable software, and analytical methodologies. In addition, this study verifies the usefulness of CPPS by estimating quantitative effects. This is expected to contribute to the proliferation of CPPS in the industry.

Implementation of Cyber-Physical Production Systems for Quality Prediction and Operation Control in Metal Casting

Science.gov (United States)

Lee, JuneHyuck; Noh, Sang Do; Kim, Hyun-Jung; Kang, Yong-Shin

2018-01-01

The prediction of internal defects of metal casting immediately after the casting process saves unnecessary time and money by reducing the amount of inputs into the next stage, such as the machining process, and enables flexible scheduling. Cyber-physical production systems (CPPS) perfectly fulfill the aforementioned requirements. This study deals with the implementation of CPPS in a real factory to predict the quality of metal casting and operation control. First, a CPPS architecture framework for quality prediction and operation control in metal-casting production was designed. The framework describes collaboration among internet of things (IoT), artificial intelligence, simulations, manufacturing execution systems, and advanced planning and scheduling systems. Subsequently, the implementation of the CPPS in actual plants is described. Temperature is a major factor that affects casting quality, and thus, temperature sensors and IoT communication devices were attached to casting machines. The well-known NoSQL database, HBase and the high-speed processing/analysis tool, Spark, are used for IoT repository and data pre-processing, respectively. Many machine learning algorithms such as decision tree, random forest, artificial neural network, and support vector machine were used for quality prediction and compared with R software. Finally, the operation of the entire system is demonstrated through a CPPS dashboard. In an era in which most CPPS-related studies are conducted on high-level abstract models, this study describes more specific architectural frameworks, use cases, usable software, and analytical methodologies. In addition, this study verifies the usefulness of CPPS by estimating quantitative effects. This is expected to contribute to the proliferation of CPPS in the industry. PMID:29734699

Multicriteria Evaluation of Product Quality

OpenAIRE

Pabedinskaitė, Arnoldina; Vitkauskas, Romualdas

2009-01-01

Product quality assessment is a complex task. The aim of this paper is to analyse the concepts of quality, different quality management models and their interaction with knowledge management models and the presented criteria system for assessing product quality. Moreover, multicriteria methods and their applicability to assessment of the product quality are analysed. On the basis of group of the product quality criteria and using the multicriteria evaluation methods, the quality of the produc...

Rhizobacterial characterization for quality control of eucalyptus biogrowth promoter products

Directory of Open Access Journals (Sweden)

Talyta Galafassi Zarpelon

Full Text Available Abstract Plant growth-promoting rhizobacteria strains from special formulations have been used to optimize eucalyptus cutting production. To undertake quality control for the formulated products, the rhizobacterial strains should be characterized to assess their purity and authentication. In the present study, we characterized nine strains of rhizobacteria, including three Bacillus subtilis (S1, S2 and 3918, two Pseudomonas sp. (MF4 and FL2, P. putida (MF2, P. fulva (Ca, Frateuria aurantia (R1, and Stenotrophomonas maltophilia (CIIb. The strains were differentiated by colony morphology after 24 h of incubation in three different solid state culture media (glucose-nutritive agar, 523 medium and yeast extract-mannitol agar, sensitivity to a panel of 28 antibiotics (expressed according to the formation of inhibition halos of bacterial growth in the presence of antibiotics, and PCR-RFLP profiles of the 16S rDNA gene produced using nine restriction enzymes. It was possible to differentiate all nine strains of rhizobacteria using their morphological characteristics and sensitivity to antibiotics. The molecular analysis allowed us to separate the strains CIIb, FL2 and R1 from the strains belonging to the genera Bacillus and Pseudomonas. By using these three methods concomitantly, we were able to determine strain purity and perform the authentication.

PROCESS VARIABILITY REDUCTION THROUGH STATISTICAL PROCESS CONTROL FOR QUALITY IMPROVEMENT

Directory of Open Access Journals (Sweden)

B.P. Mahesh

2010-09-01

Full Text Available Quality has become one of the most important customer decision factors in the selection among the competing product and services. Consequently, understanding and improving quality is a key factor leading to business success, growth and an enhanced competitive position. Hence quality improvement program should be an integral part of the overall business strategy. According to TQM, the effective way to improve the Quality of the product or service is to improve the process used to build the product. Hence, TQM focuses on process, rather than results as the results are driven by the processes. Many techniques are available for quality improvement. Statistical Process Control (SPC is one such TQM technique which is widely accepted for analyzing quality problems and improving the performance of the production process. This article illustrates the step by step procedure adopted at a soap manufacturing company to improve the Quality by reducing process variability using Statistical Process Control.

New process modeling[sic], design, and control strategies for energy efficiency, high product quality, and improved productivity in the process industries. Final project report; FINAL

International Nuclear Information System (INIS)

Ray, W. Harmon

2002-01-01

This project was concerned with the development of process design and control strategies for improving energy efficiency, product quality, and productivity in the process industries. In particular, (i) the resilient design and control of chemical reactors, and (ii) the operation of complex processing systems, was investigated. Specific topics studied included new process modeling procedures, nonlinear controller designs, and control strategies for multiunit integrated processes. Both fundamental and immediately applicable results were obtained. The new design and operation results from this project were incorporated into computer-aided design software and disseminated to industry. The principles and design procedures have found their way into industrial practice

Application of Statistical Process Control (SPC in it´s Quality control

Directory of Open Access Journals (Sweden)

Carlos Hernández-Pedrera

2015-12-01

Full Text Available The overall objective of this paper is to use the SPC to assess the possibility of improving the process of obtaining a sanitary device. As specific objectives we set out to identify the variables to be analyzed to enter the statistical control of process (SPC, analyze possible errors and variations indicated by the control charts in addition to evaluate and compare the results achieved with the study of SPC before and after monitoring direct in the production line were used sampling methods and laboratory replacement to determine the quality of the finished product, then statistical methods were applied seeking to emphasize the importance and contribution from its application to monitor corrective actions and support processes in production. It was shown that the process is under control because the results were found within established control limits. There is a tendency to be displaced toward one end of the boundary, the distribution exceeds the limits, creating the possibility that under certain conditions the process is out of control, the results also showed that the process being within the limits of quality control is operating far from the optimal conditions. In any of the study situations were obtained products outside the limits of weight and discoloration but defective products were obtained.

Quality Control in Production Processes

Directory of Open Access Journals (Sweden)

Prístavka Miroslav

2016-09-01

Full Text Available The tools for quality management are used for quality improvement throughout the whole Europe and developed countries. Simple statistics are considered one of the most basic methods. The goal was to apply the simple statistical methods to practice and to solve problems by using them. Selected methods are used for processing the list of internal discrepancies within the organization, and for identification of the root cause of the problem and its appropriate solution. Seven basic quality tools are simple graphical tools, but very effective in solving problems related to quality. They are called essential because they are suitable for people with at least basic knowledge in statistics; therefore, they can be used to solve the vast majority of problems.

Tropical Fruit Pulps: Processing, Product Standardization and Main Control Parameters for Quality Assurance

Directory of Open Access Journals (Sweden)

Carlos Eduardo de Farias Silva

2017-05-01

Full Text Available ABSTRACT Fruit pulp is the most basic food product obtained from fresh fruit processing. Fruit pulps can be cold stored for long periods of time, but they also can be used to fabricate juices, ice creams, sweets, jellies and yogurts. The exploitation of tropical fruits has leveraged the entire Brazilian fruit pulp sector due mainly to the high acceptance of their organoleptic properties and remarkable nutritional facts. However, several works published in the last decades have pointed out unfavorable conditions regarding the consumption of tropical fruit pulps. This negative scenario has been associated with unsatisfactory physico-chemical and microbiological parameters of fruits pulps as outcomes of little knowledge and improper management within the fruit pulp industry. There are protocols for delineating specific identity and quality standards (IQSs and standardized good manufacturing practices (GMP for fruit pulps, which also embrace standard operating procedures (SOPs and hazard analysis and critical control points (HACCP, although this latter is not considered mandatory by the Brazilian legislation. Unfortunately, the lack of skilled labor, along with failures in complying established protocols have impaired quality of fruit pulps. It has been necessary to collect all information available with the aim to identify the most important hazards within fruit pulp processing lines. Standardizing methods and practices within the Brazilian fruit pulp industry would assurance high quality status to tropical fruit pulps and the commercial growth of this vegetal product towards international markets.

Quality control of coated fuel particles for high temperature gas-cooled reactor

International Nuclear Information System (INIS)

Kaneko, Mitsunobu

1987-01-01

The quality control of the coated fuel particles for high temperature gas-cooled reactors is characterized by the fact that the size of the target product to be controlled is very small, and the quantity is very large. Accordingly, the sampling plan and the method of evaluating the population through satisfically treating the measured data of the samples are the important subjects to see and evaluate the quality of a batch or a lot. This paper shows the fabrication process and the quality control procedure for the coated fuel particles. The development work of a HTGR was started by Japan Atomic Energy Research Institute in 1969, and as for the production technology for coated fuel particles, Nuclear Fuel Industries, Ltd. has continued the development work. The pilot plan with the capacity of about 40 kg/year was established in 1972. The fuel product fabricated in this plant was put to the irradiation experiment and out-of-pile evaluation test. In 1983, the production capacity was expanded to 200 kg/year, and the fuel compacts for the VHTRC in JAERI were produced for two years. The basic fuel design, the fabrication process, the quality control, the process control and the quality assurance are reported. For the commercial product, the studies from the viewpoint of production and quality control costs are required. (Kako, I.)

AVLIS Production Plant Preliminary Quality Assurance Plan and Assessment

International Nuclear Information System (INIS)

1984-01-01

This preliminary Quality Assurance Plan and Assessment establishes the Quality Assurance requirements for the AVLIS Production Plant Project. The Quality Assurance Plan defines the management approach, organization, interfaces, and controls that will be used in order to provide adequate confidence that the AVLIS Production Plant design, procurement, construction, fabrication, installation, start-up, and operation are accomplished within established goals and objectives. The Quality Assurance Program defined in this document includes a system for assessing those elements of the project whose failure would have a significant impact on safety, environment, schedule, cost, or overall plant objectives. As elements of the project are assessed, classifications are provided to establish and assure that special actions are defined which will eliminate or reduce the probability of occurrence or control the consequences of failure. 8 figures, 18 tables

Quality control of 11C-carfentanil

International Nuclear Information System (INIS)

Zhang Xiaojun; Zhang Jinming; Tian Jiahe; Xiang Xiaohui

2013-01-01

To study the quality control of 11 C-Carfentanil injection, physical, chemical and biological identification were used. The chemical and radiochemical purity of 11 C-Carfentanil Injection were detected by HPLC and Flower Count system; measured the quantity of product by LC-MS, specific activity was calculated later; The PTS was used to detect endotoxin, and other quality control methods were put up to guarantee the security of its clinical application. The produce appeared colorless and transparent, the radiochemical purity was more than 98%, content of the endotoxin was less than 5 EU/mL. The result showed that 11 C-Carfentanil injection had fulfilled pharmaceutical quality control request and could be applied safely to animal experiment and clinical diagnosis. (authors)

Tc99m MDP kits, production and quality control

International Nuclear Information System (INIS)

Othman, I.; Yassine, T.; Lababidi, Z.; Kouli, M.

1992-11-01

MDP kits for labelling with Tc 99m were locally produced in different conditions, and the conditions for preparation were optimized. The quality control studies showed that the prepared kits were very good quality and comparable with that imported. Radiochemical purities ranged between 95-98% while reduced technetium ranged between 2-3% and free pertechnetate did not exceed 1%. Bioscan and biodistribution studies also showed high localization of Tc 99m in the skeleton of rats and rabbits. (author). 8 refs., 14 tabs

Stability evaluation of quality parameters for palm oil products at low temperature storage.

Science.gov (United States)

Ramli, Nur Aainaa Syahirah; Mohd Noor, Mohd Azmil; Musa, Hajar; Ghazali, Razmah

2018-07-01

Palm oil is one of the major oils and fats produced and traded worldwide. The value of palm oil products is mainly influenced by their quality. According to ISO 17025:2005, accredited laboratories require a quality control procedure with respect to monitoring the validity of tests for determination of quality parameters. This includes the regular use of internal quality control using secondary reference materials. Unfortunately, palm oil reference materials are not currently available. To establish internal quality control samples, the stability of quality parameters needs to be evaluated. In the present study, the stability of quality parameters for palm oil products was examined over 10 months at low temperature storage (6 ± 2 °C). The palm oil products tested included crude palm oil (CPO); refined, bleached and deodorized (RBD) palm oil (RBDPO); RBD palm olein (RBDPOo); and RBD palm stearin (RBDPS). The quality parameters of the oils [i.e. moisture content, free fatty acid content (FFA), iodine value (IV), fatty acids composition (FAC) and slip melting point (SMP)] were determined prior to and throughout the storage period. The moisture, FFA, IV, FAC and SMP for palm oil products changed significantly (P  0.05). The stability study indicated that the quality of the palm oil products was stable within the specified limits throughout the storage period at low temperature. The storage conditions preserved the quality of palm oil products throughout the storage period. These findings qualify the use of the palm oil products CPO, RBDPO, RBDPOo and RBDPS as control samples in the validation of test results. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

CONCRETE STRUCTURES' QUALITY CONTROL IN PRACTICE

OpenAIRE

Dolaček-Alduk, Zlata; Blanda, Miroslav

2011-01-01

The Croatian civil engineering is characterized by a lack of systematic approach to planning, control and quality assurance in all phases of project realization. The results obtained in establishing the quality management system in some segments of civil engineering production represent initial trends in solving this problem. Benefits are of two types: the achievement of quality for the contractor and obtaining that quaity is being achieved for clients. Execution of concrete structures is a c...

Physicochemical and antimicrobial properties of copaiba oil: implications on product quality control.

Science.gov (United States)

Fonseca, Renata G; Barros, Francisco M; Apel, Miriam A; Poser, Gilsane L von; Andriolli, Jo O L; Filho, Pedro C Campos; Sousa, Dhierlate F; Lobo, Ivon P; Conceiç O, Aline O

2015-01-01

The copaiba oil is a common natural product used in cosmetic industry and as a nutraceutical product. However, lack of quality control and scarce knowledge about its antimicrobial activity is a point of concern. The proposal of this study was to investigate the physicochemical properties and the antimicrobial activity of five commercial brands of copaiba oil. Acidity and ester index, refractory index, solubility in alcohol, and thin layer chromatography were performed to verify the physicochemical properties of five commercial copaiba oils sold in local pharmacies. Ultra performance liquid chromatography coupled with diode-array detection and electrospray ionization quadrupole time-of-flight mass spectrometry (UPLC-DAD/ESI-Q-TOF-MS) was used to investigate diterpene acids while the volatile compounds were analysed by gas chromatography-mass spectrometry (GC-MS). Antibacterial and antifungal activities were also evaluated by agar diffusion technique; and minimal inhibitory concentration and maximal bactericidal concentration were defined for each sample and bacteria. The physical-chemical analysis revealed heterogeneity between all samples analysed. The A1 sample showed characteristics of copaiba oil and was mainly composed by hydrocarbon sesquiterpenes (29.95% β-bisabolene, 25.65% Z-α-bergamotene and 10.27% β-cariophyllene). Among diterpene acids, the UPLCDAD/ESI-Q-TOF-MS data are compatible with presence of copalic and/or kolavenic acid (m/z 305 [M + H]+). Candida albicans was sensitive to almost all samples at high concentration and Saccaromyces. Cerevisiae showed sensitivity to A1 sample at 100 mg/mL. Although variable, all samples showed antibacterial activity. Significant activity was seen for A3 (19.0 ±0 and 15.6 ±0.5 mm), A4 (16.6 ±0.5 and 15.6 ±0 mm), and A5 (17.1 ±0 and 17.1 ±0 mm) on Staphylococcus saprophyticus and S. aureus, respectively. All samples were active against Klebsiella pneumoniae showing ≥15 mm diameter halo inhibition; and only A

FLEXURAL TESTING MACHINE AS AN OFF-LINE CONTROL SYSTEM FOR QUALITY MONITORING IN THE PRODUCTION OF BENDED CERAMIC TILES

Directory of Open Access Journals (Sweden)

Cristiano Fragassa

2016-06-01

Full Text Available The capability to bend in a controlled manner Gres Porcelain stoneware tiles passing by a very exclusive process of pyroplastic deformation opens up entirely new opportunities in utilisation of this important family of ceramics. A bended tile can be exploited in innovative applications, such as stairs, shelves, benches and even radiators, turning this element from a simple piece of furnishing in a modern functional component. But this change in functionality also requires a different approach in the quality control, both at the product and process levels, that can no longer be limited to the use of tests specified in the regulations for traditional ceramics (e.g. colour, porosity, hygroscopic .... This article describes the first device so far devised for the verification of resistance to bending of curved tiles, discussing the correct way of use. The adoption of this particular equipment as an off-line control device can represent a valid strategy for monitoring the product and process quality.

Effective use of product quality information in food supply chain logistics

OpenAIRE

Rijpkema, W.A.

2014-01-01

Food supply chains have inherent characteristics, such as variability in product quality and quality decay, which put specific demands on logistics decision making. Furthermore, food supply chain organization and control has changed significantly in the past decades by factors such as scale intensification and globalization. In practice, these characteristics and developments frequently lead to supply chain problems, such as high levels of product waste, product quality problems, and high lo...

21 CFR 864.9650 - Quality control kit for blood banking reagents.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Quality control kit for blood banking reagents... SERVICES (CONTINUED) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES Products Used In Establishments That Manufacture Blood and Blood Products § 864.9650 Quality control kit for blood banking reagents. (a...

Quality Productivity Circle in Manufacture | Achi | Nigerian Journal of ...

African Journals Online (AJOL)

A brief history of quality control and productivity is hereby traced. ... Circle management technique are discussed in its relationship with productivity. ... so should be made sound in body (and spirit) through appropriate training and motivation.

Production and quality control of fuel cladding tubes for LWRs

International Nuclear Information System (INIS)

Matsuda, Katsuhiko; Hagi, Shigeki; Anada, Hiroyuki; Abe, Hideaki; Hyodo, Shigetoshi

1994-01-01

This paper reviews the recent fabrication technology and corrosion resistance study of fuel cladding tubes for LWRs conducted by Sumitomo Metal Industries Ltd. started the research on zircaloy in 1957. In 1980, the factory exclusively for the production of cladding tubes was founded, and the mass production system on full scale was established. Thereafter, the various improvement of the production technology, the development of new products, and the heightening of the performance mainly on the corrosion resistance have been tested and studied. Recently, the works in the production processes were almost automated, and the installation of the production lines advanced, and the stabilization of product quality and the rationalization of costs are promoted. Moreover, the development of the zircaloy cladding tubes having high corrosion resistance has been advanced to cope with the long term cycle operation of LWRs hereafter. The features of zircaloy cladding tubes, the manufacturing processes, the improvement of the manufacturing technology, the improvement of the corrosion resistance and so on are reported. (K.I.)

Quality control process improvement of flexible printed circuit board by FMEA

Science.gov (United States)

Krasaephol, Siwaporn; Chutima, Parames

2018-02-01

This research focuses on the quality control process improvement of Flexible Printed Circuit Board (FPCB), centred around model 7-Flex, by using Failure Mode and Effect Analysis (FMEA) method to decrease proportion of defective finished goods that are found at the final inspection process. Due to a number of defective units that were found at the final inspection process, high scraps may be escaped to customers. The problem comes from poor quality control process which is not efficient enough to filter defective products from in-process because there is no In-Process Quality Control (IPQC) or sampling inspection in the process. Therefore, the quality control process has to be improved by setting inspection gates and IPCQs at critical processes in order to filter the defective products. The critical processes are analysed by the FMEA method. IPQC is used for detecting defective products and reducing chances of defective finished goods escaped to the customers. Reducing proportion of defective finished goods also decreases scrap cost because finished goods incur higher scrap cost than work in-process. Moreover, defective products that are found during process can reflect the abnormal processes; therefore, engineers and operators should timely solve the problems. Improved quality control was implemented for 7-Flex production lines from July 2017 to September 2017. The result shows decreasing of the average proportion of defective finished goods and the average of Customer Manufacturers Lot Reject Rate (%LRR of CMs) equal to 4.5% and 4.1% respectively. Furthermore, cost saving of this quality control process equals to 100K Baht.

Quality control in tile production

Science.gov (United States)

Kalviainen, Heikki A.; Kukkonen, Saku; Hyvarinen, Timo S.; Parkkinen, Jussi P. S.

1998-10-01

This work studies visual quality control in ceramics industry. In tile manufacturing, it is important that in each set of tiles, every single tile looks similar. For example, the tiles should have similar color and texture. Our goal is to design a machine vision system that can estimate the sufficient similarity or same appearance to the human eye. Currently, the estimation is usually done by human vision. Differing from other approaches our aim is to use accurate spectral representation of color, and we are comparing spectral features to the RGB color features. A laboratory system for color measurement is built. Experimentations with five classes of brown tiles are presented. We use chromaticity RGB features and several spectral features for classification with the k-NN classifier and with a neural network, called Self-Organizing Map. We can classify many of the tiles but there are several problems that need further investigations: larger training and test sets are needed, illuminations effects must be studied further, and more suitable spectral features are needed with more sophisticated classifiers. It is also interesting to develop further the neural approach.

Internal quality control of blood products: An experience from a tertiary care hospital blood bank from Southern Pakistan.

Science.gov (United States)

Sultan, Sadia; Zaheer, Hasan Abbas; Waheed, Usman; Baig, Mohammad Amjad; Rehan, Asma; Irfan, Syed Mohammed

2018-01-01

Internal quality control (IQC) is the backbone of quality assurance program. In blood banking, the quality control of blood products ensures the timely availability of a blood component of high quality with maximum efficacy and minimal risk to potential recipients. The main objective of this study is to analyze the IQC of blood products as an indicator of our blood bank performance. An observational cross-sectional study was conducted at the blood bank of Liaquat National Hospital and Medical College, from January 2014 to December 2015. A total of 100 units of each blood components were arbitrarily chosen during the study. Packed red cell units were evaluated for hematocrit (HCT); random platelet concentrates were evaluated for pH, yield, and culture; fresh frozen plasma (FFP) and cryoprecipitate (CP) were evaluated for unit volume, factor VIII, and fibrinogen concentrations. A total of 400 units were tested for IQC. The mean HCT of packed red cells was 69.5 ± 7.24, and in 98% units, it met the standard (<80% of HCT). The mean platelet yield was 8.8 ± 3.40 × 10 9 /L and pH was ≥6.2 in 98% bags; cultures were negative in 97% of units tested. Mean factor VIII and fibrinogen levels were found to be 84.24 ± 15.01 and 247.17 ± 49.69 for FFP, respectively. For CP, mean factor VIII and fibrinogen level were found to be 178.75 ± 86.30 and 420.7 ± 75.32, respectively. The IQC of blood products at our blood bank is in overall compliance and met recommended international standards. Implementation of standard operating procedures, accomplishment of standard guidelines, proper documentation with regular audit, and staff competencies can improve the quality performance of the transfusion services.

Increasing productivity based on quality management: Baked goods sector example

DEFF Research Database (Denmark)

Herbert-Hansen, Zaza Nadja Lee; Jacobsen, Peter

2014-01-01

This paper investigates productivity and quality management challenges in the food industry, illustrated by a case study of an SME-sized company in the Danish baked goods sector. Companies in the food industry are faced with challenges related to short shelf-life and changing customer demands...... as well as intense cost pressures. Quality control is largely manual and often based on the bakers’ intuition. Problems with reusing dough, production stops and quality issues contribute towards waste. This paper addresses the research question “Is there a relation between the dough, production stops...... through improved quality management are detailed. The paper concludes with recommendations for further research....

Incentive systems for food quality control with repeated deliveries: Salmonella control in pork production

NARCIS (Netherlands)

King, R.P.; Backus, G.B.C.; Gaag, van der M.A.

2007-01-01

This paper presents a dynamic principal-agent analysis of incentive systems for Salmonella control. The European Union will require Salmonella testing from 2008. On the basis of the producer's performance history in controlling Salmonella, the incentive systems analysed determine quality premiums to

APPLICATION OF HIDDEN MARKOV CHAINS IN QUALITY CONTROL

Directory of Open Access Journals (Sweden)

Hanife DEMIRALP

2013-01-01

Full Text Available The ever growing technological innovations and sophistication in industrial processes require adequate checks on quality. Thus, there is an increasing demand for simple and efficient quality control methods. In this regard the control charts stand out in simplicity and efficiency. In this paper, we propose a method of controlling quality based on the theory of hidden Markov chains. Based on samples drawn at different times from the production process, the method obtains the state of the process probabilistically. The main advantage of the method is that it requires no assumption on the normality of the process output.

Quality control of the 113Sn-113mIn generator

International Nuclear Information System (INIS)

Morin Zorilla, J.; Olive, E.; Isaac, M.; Cruz, J.

1989-01-01

Methods for quality control of 113 Sn- 113m In generators are compared and recommended the most convenient to applicate in hospitals and in more specialized quality control laboratories. The quality of 113 Sn- 113m In generator produced by POLATOM (Poland) is also evaluated. The product met the requirements of the International Pharmacopeia

CONTRIBUTION TO THE IMPROVEMENT OF PRODUCTS QUALITY IN BAKING INDUSTRY

Directory of Open Access Journals (Sweden)

Aleksandar Marić

2009-09-01

Full Text Available Food industry occupies special place in the processing industry, especially when we talk on the manufacturing of bakery products. Variable products quality on the market initiated the authors of this study to make an attempt, using comparative analysis of methods for quality control that are at most applied in bakery plants and other "convenient" methods to indicate the shortcomings and to argue convenience of using of methods that would improve testing of the quality. That approach could create a base for designing of model of quality improvement the baking industry.

Patients with Gout Treated with Conventional Urate-lowering Therapy: Association with Disease Control, Health-related Quality of Life, and Work Productivity.

Science.gov (United States)

Wood, Robert; Fermer, Steve; Ramachandran, Sulabha; Baumgartner, Scott; Morlock, Robert

2016-10-01

Implications of inadequate gout control were assessed through health-related quality of life (HRQOL) and work productivity of patients with gout adequately controlled while taking conventional urate-lowering therapy (ULT) for ≥ 3 months vs those whose gout was inadequately controlled. Retrospective data were drawn from the Adelphi Disease Specific Programme (DSP), a cross-sectional survey of patients with gout in France, Germany, the United Kingdom, and the United States. Patients completed these questionnaires: EQ-5D (3L), Patient Reported Outcomes Measurement Information System (PROMIS) Health Assessment Questionnaire (HAQ), and Work Productivity and Activity Impairment. Inadequate control was defined as the most recent serum uric acid (SUA) level > 6 mg/dl (> 360 µmol/l) or ≥ 2 flares in the last 12 months; adequate control as SUA level ≤ 6 mg/dl (≤ 360 µmol/l) and 0 flares. Appropriate statistical tests were used to assess differences between groups. There were 836 (69%) inadequately and 368 (31%) adequately controlled gout cases. Mean age was 61 and 63 years and duration of current ULT was 32 and 57 months, respectively. Patients experiencing inadequate control reported significantly worse functioning and HRQOL, as measured by the EQ-5D (0.790 vs 0.877; difference: -0.087; p work time missed: 4.5% vs 1.3%; impairment while working: 19.1% vs 5.2%; overall work impairment: 20.4% vs 5.6%; activity impairment: 20.3% vs 5.3%; all p quality of life, and work productivity. Gout treatment strategies to improve disease control may lead to improvements in HRQOL and productivity.

Production and quality control of optical elements for the end cap hadron calorimeter of the CMS setup

CERN Document Server

Abramov, V V; Korablev, A V; Korneev, Yu P; Krinitsyn, A N; Kryshkin, V I; Markov, A A; Talov, VV; Turchanovich, L K; Volkov, A A; Zaichenko, A A

2005-01-01

An end cap hadron calorimeter, in which scintillators with wavelength-shifting fibers are used as the active elements, has been designed for the compact muon spectrometer (CMS) now under construction at CERN. A total of 1368 optical elements containing 21 096 scintillators have already been manufactured. The production and quality control procedures for these optical elements are described. copy 2005 Pleiades Publishing, Inc.

Product quality, service reliability and management of operations at ...

African Journals Online (AJOL)

High product quality, service reliability, and management of operations are key factors in business growth and sustainability. Analyzing “The Starbucks Experience” is a pedagogical approach to reinforcing the concepts of control and management of quality, service reliability, and efficient operations in action. The objective ...

Procedure guide for the implementation of quality management program in products and services link with the utilization of tracers technology (TT) and Nucleonic Control System

International Nuclear Information System (INIS)

Resnizky, S.; Banados Perez, H.; Longo, G.; Rodriguez Cardona, R.L.; Sebastian Calvo, C.; Kohnenkamp O, I.; Duran P, O.

2000-01-01

This Manual was elaborated in the mark of the project RLA/8/024 ARCAL XLII 'Industrial Applications of the Tracer Technology and Nucleonic Control Systems'. The objective of the present Quality Manual is to spread the Quality Policy and to describe the form of implementing the Quality Management System, according to the requirements of the Standard ISO 9001:2000. It is applied to the design, development, implementation and maintenance of the products of the Organization of Tracers Technology (TT) and Nucleonic Control Systems (SCN). It have 9 Section: I. Introduction, II. Normative references, III. Definitions, IV. Quality Management System; V. Direction Responsibility; VI. Resources Management; VII. Products Accomplishment; VIII. Measurement, Analysis and Improvement and 7 Annex

The centralised production and quality control of radiopharmaceuticals

International Nuclear Information System (INIS)

Boyd, R.E.

1980-01-01

The concept of a centralised facility for the production testing and distribution within a metropolitan, regional or national area, although not new, is now gaining widespread acceptance in many countries. The rationalisation of resources and operation on a large scale ensures savings in costs. The aim of the centralised radiopharmacy is the regular and routine provision of high quality radiopharmaceuticals and to do this it must have access to a multidisciplinary group of scientists working with the support of trained technicians. These specialists require working facilities which are quite unique and designed according to complex engineering criteria to ensure the safety both of the environment and the patient. Production processes and equipment must be selected on the basis of reliability, minimal operational skill and the ease of maintenance. The infra structure of the organisation must provide the logistic support to ensure that the products from the centralized radiopharmacy reach the end-users at the times, places and in the amounts requested. This should be achieved with a success rate which engenders confidence. The Australian Atomic Energy Commission has operated a national radiopharmacy for more than a decade, delivering more than 150000 patient doses per year over the vast distances which separate the Australian capital cities. These activities have helped nuclear medicine to flourish in Australia; it is expected that the creation of the radioisotope production facilities at PUSPATI will have the same effect in Malaysia. (author)

Quality Control Applications

CERN Document Server

Chorafas, Dimitris N

2013-01-01

Quality control is a constant priority in electrical, mechanical, aeronautical, and nuclear engineering – as well as in the vast domain of electronics, from home appliances to computers and telecommunications. Quality Control Applications provides guidance and valuable insight into quality control policies; their methods, their implementation, constant observation and associated technical audits. What has previously been a mostly mathematical topic is translated here for engineers concerned with the practical implementation of quality control. Once the fundamentals of quality control are established, Quality Control Applications goes on to develop this knowledge and explain how to apply it in the most effective way. Techniques are described and supported using relevant, real-life, case studies to provide detail and clarity for those without a mathematical background. Among the many practical examples, two case studies dramatize the importance of quality assurance: A shot-by-shot analysis of the errors made ...

Analysis of an industrial production suspension of Bacillus lentus subtilisin crystals by powder diffraction: a powerful quality-control tool

DEFF Research Database (Denmark)

Frankær, Christian Grundahl; Moroz, Olga V.; Turkenburg, Johan P.

2014-01-01

. A controlled crystallization experiment with a highly purified Savinase sample allowed the growth of single crystals of the form identified by XRPD; their structure was solved and refined to a resolution of 1.17 Å with an R of 9.2% and an Rfree of 11.8%. Thus, there are at least three polymorphs present...... in the production suspension, albeit with the 1ndq -like microcrystals predominating. It is shown how the two techniques can provide invaluable and complementary information for such a production suspension and it is proposed that XRPD provides an excellent quality-control tool for such suspensions....

Product quality driven food process design

NARCIS (Netherlands)

Hadiyanto, M.

2007-01-01

Consumers evaluate food products on their quality, and thus the product quality is a main target in industrial food production. In the last decade there has been a remarkable increase of interest of the food industry to put food product quality central in innovation. However, quality itself is

Improving the quality of pork and pork products (EU project)

DEFF Research Database (Denmark)

Christensen, Mette; Grunert, Klaus G.; Bonneau, M.

2008-01-01

demands. A large EU-project (Q-PorkChains) funded by EU 6th framework programme was initiated in January 2007. The aim of Q-PorkChains is to improve the quality of pork and its products for the consumer and to develop innovative, integrated and sustainable food production chains with low environmental....... The European Unions self-sufficiency and leading position in the global market for pork and pork products is challenged by a number of non-European countries. Therefore, there is a need for developing innovative, integrated, and sustainable food production chains of high quality pork products matching consumer...... impact. Q-PorkChains is composed of six research modules (consumer and citizen demands, pig production, product development, pork chain management, molecular quality control and knowledge synthesis) and two horizontal modules focusing on implementation of obtained knowledge in pilot and demonstration...

ISO 9000. Guidelines to increased costs and reduced product quality

International Nuclear Information System (INIS)

Reedy, R.F.

1994-01-01

Many US companies are considering being registered to the provisions of ISO 9000, International Standards for Quality Management. One important problem with the document is that ISO 9000 is not focused on control of product quality. The quality assurance rules established in ISO 9000 have been used in the US for more than 25 years with disastrous financial consequences and little, if any, improvement in quality and safety. These rules are so reliant on documentation and strict compliance that ensuring products comply with specifications has become a secondary issues. That is not what was intended, but it is the result. ISO 9000 program can work effectively only when the top executive responsible for engineering or production takes full responsibility for interpretation and implementation of the quality assurance program. 3 refs., 1 tab

[Quality assurance in food production in Europe according to ISO 90000 and HACCP (Hazard Analysis and Critical Control Points)].

Science.gov (United States)

Jouve, J L

1996-12-01

HACCP is intended to make food protection programs evolve from a mainly retrospective quality control toward a preventative quality assurance approach and to provide an increased confidence in food safety. In parallel, the continuous evolution of quality concepts in the food industry resulted in the development of quality systems and quality assurance techniques with regard to the EN 29,000 (ISO 9000) series of standards. Specific to the food industry, HACCP can be seen as a very effective method to prepare specific Safety Assurance Plans (cf. the quality assurance plan concept) within a quality systems approach (Jouve, 1993). By reference to ISO 8402, a Quality Assurance Plan (QAP) basically sets out "the specific quality practices, resources and sequence of activities relevant to a particular product, service, contract or project". Quality assurance plans are more particularly useful for projects relating to new products or processes and/or comprising inter-related tasks whose interaction may be complex. In addition, in contractual or regulatory situations, such plans can be used to demonstrate the supplier's capability to meet identified objectives, specification or standards. In the food industry, the management of safety is a critical and complex issue which fits very well in the scope of application of a specific QAP; it is also where the use of HACCP is otherwise recommended by priority.

Multivariate statistical process control in product quality review assessment - A case study.

Science.gov (United States)

Kharbach, M; Cherrah, Y; Vander Heyden, Y; Bouklouze, A

2017-11-01

According to the Food and Drug Administration and the European Good Manufacturing Practices (GMP) guidelines, Annual Product Review (APR) is a mandatory requirement in GMP. It consists of evaluating a large collection of qualitative or quantitative data in order to verify the consistency of an existing process. According to the Code of Federal Regulation Part 11 (21 CFR 211.180), all finished products should be reviewed annually for the quality standards to determine the need of any change in specification or manufacturing of drug products. Conventional Statistical Process Control (SPC) evaluates the pharmaceutical production process by examining only the effect of a single factor at the time using a Shewhart's chart. It neglects to take into account the interaction between the variables. In order to overcome this issue, Multivariate Statistical Process Control (MSPC) can be used. Our case study concerns an APR assessment, where 164 historical batches containing six active ingredients, manufactured in Morocco, were collected during one year. Each batch has been checked by assaying the six active ingredients by High Performance Liquid Chromatography according to European Pharmacopoeia monographs. The data matrix was evaluated both by SPC and MSPC. The SPC indicated that all batches are under control, while the MSPC, based on Principal Component Analysis (PCA), for the data being either autoscaled or robust scaled, showed four and seven batches, respectively, out of the Hotelling T 2 95% ellipse. Also, an improvement of the capability of the process is observed without the most extreme batches. The MSPC can be used for monitoring subtle changes in the manufacturing process during an APR assessment. Copyright © 2017 Académie Nationale de Pharmacie. Published by Elsevier Masson SAS. All rights reserved.

Real-time product attribute control to manufacture antibodies with defined N-linked glycan levels.

Science.gov (United States)

Zupke, Craig; Brady, Lowell J; Slade, Peter G; Clark, Philip; Caspary, R Guy; Livingston, Brittney; Taylor, Lisa; Bigham, Kyle; Morris, Arvia E; Bailey, Robert W

2015-01-01

Pressures for cost-effective new therapies and an increased emphasis on emerging markets require technological advancements and a flexible future manufacturing network for the production of biologic medicines. The safety and efficacy of a product is crucial, and consistent product quality is an essential feature of any therapeutic manufacturing process. The active control of product quality in a typical biologic process is challenging because of measurement lags and nonlinearities present in the system. The current study uses nonlinear model predictive control to maintain a critical product quality attribute at a predetermined value during pilot scale manufacturing operations. This approach to product quality control ensures a more consistent product for patients, enables greater manufacturing efficiency, and eliminates the need for extensive process characterization by providing direct measures of critical product quality attributes for real time release of drug product. © 2015 American Institute of Chemical Engineers.

[Development of whole process quality control and management system of traditional Chinese medicine decoction pieces based on traditional Chinese medicine quality tree].

Science.gov (United States)

Yu, Wen-Kang; Dong, Ling; Pei, Wen-Xuan; Sun, Zhi-Rong; Dai, Jun-Dong; Wang, Yun

2017-12-01

The whole process quality control and management of traditional Chinese medicine (TCM) decoction pieces is a system engineering, involving the base environment, seeds and seedlings, harvesting, processing and other multiple steps, so the accurate identification of factors in TCM production process that may induce the quality risk, as well as reasonable quality control measures are very important. At present, the concept of quality risk is mainly concentrated in the aspects of management and regulations, etc. There is no comprehensive analysis on possible risks in the quality control process of TCM decoction pieces, or analysis summary of effective quality control schemes. A whole process quality control and management system for TCM decoction pieces based on TCM quality tree was proposed in this study. This system effectively combined the process analysis method of TCM quality tree with the quality risk management, and can help managers to make real-time decisions while realizing the whole process quality control of TCM. By providing personalized web interface, this system can realize user-oriented information feedback, and was convenient for users to predict, evaluate and control the quality of TCM. In the application process, the whole process quality control and management system of the TCM decoction pieces can identify the related quality factors such as base environment, cultivation and pieces processing, extend and modify the existing scientific workflow according to their own production conditions, and provide different enterprises with their own quality systems, to achieve the personalized service. As a new quality management model, this paper can provide reference for improving the quality of Chinese medicine production and quality standardization. Copyright© by the Chinese Pharmaceutical Association.

The influence of farmland pollution on the quality and safety of agricultural products

Science.gov (United States)

Ma, Z. L.; Li, L. Y.; Ye, C.; Lin, X. Y.; B, C.; Wei

2018-02-01

The quality and safety of agricultural products is not only a major livelihood issues for people’s health, but also the main barriers to international trade of agricultural products nowadays. The soil is the foundation to the production of agricultural products and the guarantee of agricultural development. The farmland soil quality is directly related to the quality and safety of agricultural products. Our country’s soil has been polluted by a series of pollution, Such as the excessive discharge of industrial wastes, the encroachment of household waste, and the unreasonable use of pesticides and fertilizers. Soil degradation is a serious threat to the quality and safety of agricultural products, so eliminating soil degradation is the fundamental way out for quality and safety of agricultural products. By analyzing problems of the quality and safety of agricultural products in our country, and exploring the farmland soil influence on the quality and safety of agricultural products. This article provides a reference for improving the control level of quality and safety of agricultural products and the farmland soil quality.

Use of statistical process control in the production of blood components

DEFF Research Database (Denmark)

Magnussen, K; Quere, S; Winkel, P

2008-01-01

Introduction of statistical process control in the setting of a small blood centre was tested, both on the regular red blood cell production and specifically to test if a difference was seen in the quality of the platelets produced, when a change was made from a relatively large inexperienced...... by an experienced staff with four technologists. We applied statistical process control to examine if time series of quality control values were in statistical control. Leucocyte count in red blood cells was out of statistical control. Platelet concentration and volume of the platelets produced by the occasional...... occasional component manufacturing staff to an experienced regular manufacturing staff. Production of blood products is a semi-automated process in which the manual steps may be difficult to control. This study was performed in an ongoing effort to improve the control and optimize the quality of the blood...

BRAND AND QUALITY CONTROL OF GARMENT PRODUCTS IN THE BANGLADESH GARMENT INDUSTRY

OpenAIRE

Hoshen, Mohammad

2014-01-01

Abstract This thesis paper contains information on the garment industry of Bangladesh. The garment business plays a vital part in global market. There are a large numbers of world renowned apparel companies that outsource their products in Bangladesh. The aim of the thesis is to explicate quality management in garment production and the brand protection process during outsourcing in Bangladesh. The theoretical part of the thesis provides basic information about garment products, the glo...

Statistical Methods in Assembly Quality Management of Multi-Element Products on Automatic Rotor Lines

Science.gov (United States)

Pries, V. V.; Proskuriakov, N. E.

2018-04-01

To control the assembly quality of multi-element mass-produced products on automatic rotor lines, control methods with operational feedback are required. However, due to possible failures in the operation of the devices and systems of automatic rotor line, there is always a real probability of getting defective (incomplete) products into the output process stream. Therefore, a continuous sampling control of the products completeness, based on the use of statistical methods, remains an important element in managing the quality of assembly of multi-element mass products on automatic rotor lines. The feature of continuous sampling control of the multi-element products completeness in the assembly process is its breaking sort, which excludes the possibility of returning component parts after sampling control to the process stream and leads to a decrease in the actual productivity of the assembly equipment. Therefore, the use of statistical procedures for continuous sampling control of the multi-element products completeness when assembled on automatic rotor lines requires the use of such sampling plans that ensure a minimum size of control samples. Comparison of the values of the limit of the average output defect level for the continuous sampling plan (CSP) and for the automated continuous sampling plan (ACSP) shows the possibility of providing lower limit values for the average output defects level using the ACSP-1. Also, the average sample size when using the ACSP-1 plan is less than when using the CSP-1 plan. Thus, the application of statistical methods in the assembly quality management of multi-element products on automatic rotor lines, involving the use of proposed plans and methods for continuous selective control, will allow to automating sampling control procedures and the required level of quality of assembled products while minimizing sample size.

A quality assurance initiative for commercial-scale production in high-throughput cryopreservation of blue catfish sperm.

Science.gov (United States)

Hu, E; Liao, T W; Tiersch, T R

2013-10-01

Cryopreservation of fish sperm has been studied for decades at a laboratory (research) scale. However, high-throughput cryopreservation of fish sperm has recently been developed to enable industrial-scale production. This study treated blue catfish (Ictalurus furcatus) sperm high-throughput cryopreservation as a manufacturing production line and initiated quality assurance plan development. The main objectives were to identify: (1) the main production quality characteristics; (2) the process features for quality assurance; (3) the internal quality characteristics and their specification designs; (4) the quality control and process capability evaluation methods, and (5) the directions for further improvements and applications. The essential product quality characteristics were identified as fertility-related characteristics. Specification design which established the tolerance levels according to demand and process constraints was performed based on these quality characteristics. Meanwhile, to ensure integrity throughout the process, internal quality characteristics (characteristics at each quality control point within process) that could affect fertility-related quality characteristics were defined with specifications. Due to the process feature of 100% inspection (quality inspection of every fish), a specific calculation method, use of cumulative sum (CUSUM) control charts, was applied to monitor each quality characteristic. An index of overall process evaluation, process capacity, was analyzed based on in-control process and the designed specifications, which further integrates the quality assurance plan. With the established quality assurance plan, the process could operate stably and quality of products would be reliable. Copyright © 2013 Elsevier Inc. All rights reserved.

Visualization and Quality Control Web Tools for CERES Products

Science.gov (United States)

Mitrescu, C.; Doelling, D. R.

2017-12-01

The NASA CERES project continues to provide the scientific communities a wide variety of satellite-derived data products such as observed TOA broadband shortwave and longwave observed fluxes, computed TOA and Surface fluxes, as well as cloud, aerosol, and other atmospheric parameters. They encompass a wide range of temporal and spatial resolutions, suited to specific applications. CERES data is used mostly by climate modeling communities but also by a wide variety of educational institutions. To better serve our users, a web-based Ordering and Visualization Tool (OVT) was developed by using Opens Source Software such as Eclipse, java, javascript, OpenLayer, Flot, Google Maps, python, and others. Due to increased demand by our own scientists, we also implemented a series of specialized functions to be used in the process of CERES Data Quality Control (QC) such as 1- and 2-D histograms, anomalies and differences, temporal and spatial averaging, side-by-side parameter comparison, and others that made the process of QC far easier and faster, but more importantly far more portable. With the integration of ground site observed surface fluxes we further facilitate the CERES project to QC the CERES computed surface fluxes. An overview of the CERES OVT basic functions using Open Source Software, as well as future steps in expanding its capabilities will be presented at the meeting.

Application of Proteomics in Food Technology and Food Biotechnology: Process Development, Quality Control and Product Safety

Directory of Open Access Journals (Sweden)

Dajana Gašo-Sokač

2010-01-01

Full Text Available Human food is a very complex biological mixture and food processing and safety are very important and essential disciplines. Proteomics technology using different high-performance separation techniques such as two-dimensional gel electrophoresis, one-dimensional and multidimensional chromatography, combined with high-resolution mass spectrometry has the power to monitor the protein composition of foods and their changes during the production process. The use of proteomics in food technology is presented, especially for characterization and standardization of raw materials, process development, detection of batch-to-batch variations and quality control of the final product. Further attention is paid to the aspects of food safety, especially regarding biological and microbial safety and the use of genetically modified foods.

Commercial Probiotic Products: A Call for Improved Quality Control. A Position Paper by the ESPGHAN Working Group for Probiotics and Prebiotics.

Science.gov (United States)

Kolaček, Sanja; Hojsak, Iva; Berni Canani, Roberto; Guarino, Alfredo; Indrio, Flavia; Orel, Rok; Pot, Bruno; Shamir, Raanan; Szajewska, Hania; Vandenplas, Yvan; van Goudoever, Johannes; Weizman, Zvi

2017-07-01

Probiotics have been proposed for a number of indications ranging from the hypothetical long-term immunomodulatory effects to proven benefits in the management of different clinical conditions.An increasing number of commercial products containing probiotics are available. In those products, irrespective if it is food, food supplement, medical food, or drug, the probiotic microorganisms have to be present in a sufficient number by the end of the shelf-life, to pass through the gastrointestinal tract resisting acid and bile, to colonize the gut, and to retain functional properties required to obtain the suggested beneficial effect. Finally, it should be contamination-free.Studies organized worldwide and summarized in this article have shown that inconsistencies and deviations from the information provided on the product label are surprisingly common. Frequently strains are misidentified and misclassified, products are occasionally contaminated, sometimes with even facultative or obligatory pathogens, strains are not viable, the labeled number of colonies cannot be verified, or the functional properties are diminished to the extent that preclude the proposed health benefit. As the probiotic preparations are commonly used for a wide range of conditions, the aim of the Working Group was to summarize results of the studies looking into the quality of the probiotic products and to raise the awareness of the important issue of their quality control.Based on the results obtained, we strongly suggest a more stringent quality control process. This process should ensure that the probiotic content as mentioned on the label meets the actual content throughout the shelf life of the product, while no contamination is present.

Chemical and physical quality control of the HIPPURAN-131I

International Nuclear Information System (INIS)

Morin Zorilla, J.; Olive, E.; Isaac, M.; Cruz, J.

1989-01-01

Some physico-chemical methods for analytical control of Hippuran- 131 I are compared. The most convenient to applicate in hospitals and in more specialized quality control laboratories are recommended. The quality of Hippuran- 131 I produced by ISOTOP (USSR) is also evaluated. The product met the requirement of the International Pharmacopeia

Automated Quality Control of in Situ Soil Moisture from the North American Soil Moisture Database Using NLDAS-2 Products

Science.gov (United States)

Ek, M. B.; Xia, Y.; Ford, T.; Wu, Y.; Quiring, S. M.

2015-12-01

The North American Soil Moisture Database (NASMD) was initiated in 2011 to provide support for developing climate forecasting tools, calibrating land surface models and validating satellite-derived soil moisture algorithms. The NASMD has collected data from over 30 soil moisture observation networks providing millions of in situ soil moisture observations in all 50 states as well as Canada and Mexico. It is recognized that the quality of measured soil moisture in NASMD is highly variable due to the diversity of climatological conditions, land cover, soil texture, and topographies of the stations and differences in measurement devices (e.g., sensors) and installation. It is also recognized that error, inaccuracy and imprecision in the data set can have significant impacts on practical operations and scientific studies. Therefore, developing an appropriate quality control procedure is essential to ensure the data is of the best quality. In this study, an automated quality control approach is developed using the North American Land Data Assimilation System phase 2 (NLDAS-2) Noah soil porosity, soil temperature, and fraction of liquid and total soil moisture to flag erroneous and/or spurious measurements. Overall results show that this approach is able to flag unreasonable values when the soil is partially frozen. A validation example using NLDAS-2 multiple model soil moisture products at the 20 cm soil layer showed that the quality control procedure had a significant positive impact in Alabama, North Carolina, and West Texas. It had a greater impact in colder regions, particularly during spring and autumn. Over 433 NASMD stations have been quality controlled using the methodology proposed in this study, and the algorithm will be implemented to control data quality from the other ~1,200 NASMD stations in the near future.

Quality control for 12 batch of DTPA-Sn

International Nuclear Information System (INIS)

Isaac, M.; Gamboa, R.; Leyva, R.; Hernandez, I.; Turino, D.

1994-01-01

The quality control is carry out at 12 batch of DTPA-Sn for labeling with 99 m Tc. The instrumental methods of analysis and control charts were discussed in order to find a warranty time for the product. (author). 2 refs, 3 figs, 1 tab

Optimum profit model considering production, quality and sale problem

Science.gov (United States)

Chen, Chung-Ho; Lu, Chih-Lun

2011-12-01

Chen and Liu ['Procurement Strategies in the Presence of the Spot Market-an Analytical Framework', Production Planning and Control, 18, 297-309] presented the optimum profit model between the producers and the purchasers for the supply chain system with a pure procurement policy. However, their model with a simple manufacturing cost did not consider the used cost of the customer. In this study, the modified Chen and Liu's model will be addressed for determining the optimum product and process parameters. The authors propose a modified Chen and Liu's model under the two-stage screening procedure. The surrogate variable having a high correlation with the measurable quality characteristic will be directly measured in the first stage. The measurable quality characteristic will be directly measured in the second stage when the product decision cannot be determined in the first stage. The used cost of the customer will be measured by adopting Taguchi's quadratic quality loss function. The optimum purchaser's order quantity, the producer's product price and the process quality level will be jointly determined by maximising the expected profit between them.

Intergrated approach to quality control procedures of radioisotopes and radiopharmaceuticals

International Nuclear Information System (INIS)

Rohani Mohamad

1986-01-01

Various aspects of the quality control procedures for radioisotopes and radiopharmaceuticals have been discussed. The paper high lighted those procedures that are important in ensuring the efficacy of the product. It also gives a general idea of the various procedures that are actually carried out by the Quality Control Section. (A.J.)

QUANTIFYING SUPPLIERS’ PRODUCT QUALITY: AN EXPLORATORY PRODUCT AUDIT METHOD

Directory of Open Access Journals (Sweden)

S. Avakh Darestani

2012-01-01

Full Text Available

ENGLISH ABSTRACT:The quality of the raw material and supplied product from suppliers plays a critical role in the quality of the final product. It has become the norm that vehicle manufacturers require their suppliers to measure product quality and service with a product audit method. Measuring quality of product is emphasised by QS9000 VDA6.5 and ISO/TS16949. From a competitive standpoint, and also to see continuous improvement in business, companies need to monitor their suppliers’ performance. Quality and delivery are two very important indicators of supplier performance. This paper presents a statistical method for measuring the quality of supplied product. This method allocates different weights to variables and attributes characteristics. Moreover, following normal distribution, the tolerance zone is divided to three regions with different scores. Therefore, the quality of suppliers’ products can be monitored based on the Product Quality Audit Score (PQAS. However, this method may be employed for organisations to monitor their raw material, work-in-process parts, and final product. It can be an indicator to monitor supplier quality behaviour.

AFRIKAANSE OPSOMMING: Die gehalte van grondstowwe en produkte/komponente wat deur leweransiers verskaf word, speel ‘n kritiese rol in die gehalte van die finale produk. Dit het die norm geword in die motorvervaardigingsbedryf dat daar van leweransiers verwag word om hulle produkkwaliteit en –diens te meet by wyse van ‘n produkouditmetode. Die meting van produkkwaliteit word benadruk deur QS9000 VDA6.5 en ISO/TS16949. Uit ‘n mededingingshoek en ook om kontinue verbetering te monitor, is dit noodsaaklik dat leweransiers se verrigting gemeet word. Gehalte en aflewering is twee van die belangrikste indikatore van leweransiersverrigting. In hierdie artikel word ‘n statistiese model voorgehou vir die meting van die kwaliteit van die gelewerde produk. Die metode ken verskillende

Visual inspection as one of the important elements of the quality control

Directory of Open Access Journals (Sweden)

Paweł Szklarzyk

2014-06-01

Full Text Available Quality control of the production process allows to detect incompatibilities. One of the key elements of quality control is a visual inspection. The object of the research is to determine the essential elements having an impact on visual inspections. Research was carried out according to the BOST method designed at the Institute of Production Engineering, Technical University of Czestochowa

The process of managerial control in quality improvement initiatives.

Science.gov (United States)

Slovensky, D J; Fottler, M D

1994-11-01

The fundamental intent of strategic management is to position an organization with in its market to exploit organizational competencies and strengths to gain competitive advantage. Competitive advantage may be achieved through such strategies as low cost, high quality, or unique services or products. For health care organizations accredited by the Joint Commission on Accreditation of Healthcare Organizations, continually improving both processes and outcomes of organizational performance--quality improvement--in all operational areas of the organization is a mandated strategy. Defining and measuring quality and controlling the quality improvement strategy remain problematic. The article discusses the nature and processes of managerial control, some potential measures of quality, and related information needs.

Improving lactate metabolism in an intensified CHO culture process: productivity and product quality considerations.

Science.gov (United States)

Xu, Sen; Hoshan, Linda; Chen, Hao

2016-11-01

In this study, we discussed the development and optimization of an intensified CHO culture process, highlighting medium and control strategies to improve lactate metabolism. A few strategies, including supplementing glucose with other sugars (fructose, maltose, and galactose), controlling glucose level at Productivity and product quality attributes differences between batch, fed-batch, and concentrated fed-batch cultures were discussed. The importance of process and cell metabolism understanding when adapting the existing process to a new operational mode was demonstrated in the study.

[Quality process control system of Chinese medicine preparation based on "holistic view"].

Science.gov (United States)

Wang, Ya-Qi; Jiao, Jiao-Jiao; Wu, Zhen-Feng; Zheng, Qin; Yang, Ming

2018-01-01

"High quality, safety and effectiveness" are the primary principles for the pharmaceutical research and development process in China. The quality of products relies not only on the inspection method, but also on the design and development, process control and standardized management. The quality depends on the process control level. In this paper, the history and current development of quality control of traditional Chinese medicine (TCM) preparations are reviewed systematically. Based on the development model of international drug quality control and the misunderstanding of quality control of TCM preparations, the reasons for impacting the homogeneity of TCM preparations are analyzed and summarized. According to TCM characteristics, efforts were made to control the diversity of TCM, make "unstable" TCM into "stable" Chinese patent medicines, put forward the concepts of "holistic view" and "QbD (quality by design)", so as to create the "holistic, modular, data, standardized" model as the core of TCM preparation quality process control model. Scientific studies shall conform to the actual production of TCM preparations, and be conducive to supporting advanced equipment and technology upgrade, thoroughly applying the scientific research achievements in Chinese patent medicines, and promoting the cluster application and transformation application of TCM pharmaceutical technology, so as to improve the quality and effectiveness of the TCM industry and realize the green development. Copyright© by the Chinese Pharmaceutical Association.

CUSTOMER SERVICES AND PRODUCT QUALITY

Directory of Open Access Journals (Sweden)

NEAMŢU Liviu

2013-04-01

Full Text Available Objective level of product is a combination of material elements. They are supplemented by satisfying highly heterogeneous and complex motivations, representing highly diverse subjective functions associated to product until individualization for each type of consumption. Thus it observes highly surprising developments of subjective function associated with a product and which determines in the consumer's opinion the quality level of the product. The present study examines the role of associated services covering the subjective function of the product in view of the fact that the utility or subjective function is dependent on elements such as style, fashion and fads. Consumers will no longer accept products with average quality of related services. For a company that wants to stay in the market and achieve profitability, the only solution is moving towards a complete product package type goods-services. Associated services are thus an indicator of quality and the best customer loyalty insurance policy, there is a close relationship between the quality of services provided by a firm, customer satisfaction and company profitability.

The Quality Control of the LHC Continuous Cryostat Interconnections

CERN Document Server

Bertinelli, F; Bozzini, D; Cruikshank, P; Fessia, P; Grimaud, A; Kotarba, A; Maan, W; Olek, S; Poncet, A; Russenschuck, Stephan; Savary, F; Sulek, Z; Tock, J P; Tommasini, D; Vaudaux, L; Williams, L

2008-01-01

The interconnections between the Large Hadron Collider (LHC) magnets have required some 40 000 TIG welded joints and 65 000 electrical splices. At the level of single joints and splices, non-destructive techniques find limited application: quality control is based on the qualification of the process and of operators, on the recording of production parameters and on production samples. Visual inspection and process audits were the main techniques used. At the level of an extended chain of joints and splices - from a 53.5 m half-cell to a complete 2.7 km arc sector - quality control is based on vacuum leak tests, electrical tests and RF microwave reflectometry that progressively validated the work performed. Subsequent pressure tests, cryogenic circuits flushing with high pressure helium and cool-downs revealed a few unseen or new defects. This paper presents an overview of the quality control techniques used, seeking lessons applicable to similar large, complex projects.

Module-based quality system functionality evaluation in production logistics

Energy Technology Data Exchange (ETDEWEB)

Khabbazi, M.R.; Wikander, J.; Onori, M.; Maffei, A.; Chen, D.

2016-07-01

This paper addresses a comprehensive modeling and functionality evaluation of a module-based quality system in production logistics at the highest domain abstract level of business processes. All domain quality business processes and quality data transactions are modeled using BPMN and UML tools and standards at the business process and data modeling. A modular web-based prototype is developed to evaluate the models addressing the quality information system functionality requirements and modularity in production logistics through data scenarios and data queries. Using the object-oriented technique in design at the highest domain level, the proposed models are subject further development in the lower levels for the implementing case. The models are specifically able to manipulate all quality operations including remedy and control in a lot-based make-to-order production logistics system as an individual module. Due to the specification of system as domain design structure, all proposed BPMs, data models, and the actual database prototype are seen referential if not a solution as a practical “to-be” quality business process re-engineering template. This paper sets out to provide an explanatory approach using different practical technique at modeling steps as well as the prototype implementation. (Author)

Management Model for efficient quality control in new buildings

Directory of Open Access Journals (Sweden)

C. E. Rodríguez-Jiménez

2017-09-01

Full Text Available The management of the quality control of each building process is usually set up in Spain from different levels of demand. This work tries to obtain a model of reference, to compare the quality control of the building process of a specific product (building, and to be able to evaluate its warranty level. In the quest of this purpose, we take credit of specialized sources and 153 real cases of Quality Control were carefully revised using a multi-judgment method. Applying different techniques to get a specific valuation (impartial of the input parameters through Delphi’s method (17 experts query, whose matrix treatment with the Fuzzy-QFD tool condenses numerical references through a weighted distribution of the selected functions and their corresponding conditioning factors. The model thus obtained (M153 is useful in order to have a quality control reference to meet the expectations of the quality.

Use of a small molecule cell cycle inhibitor to control cell growth and improve specific productivity and product quality of recombinant proteins in CHO cell cultures.

Science.gov (United States)

Du, Zhimei; Treiber, David; McCarter, John D; Fomina-Yadlin, Dina; Saleem, Ramsey A; McCoy, Rebecca E; Zhang, Yuling; Tharmalingam, Tharmala; Leith, Matthew; Follstad, Brian D; Dell, Brad; Grisim, Brent; Zupke, Craig; Heath, Carole; Morris, Arvia E; Reddy, Pranhitha

2015-01-01

The continued need to improve therapeutic recombinant protein productivity has led to ongoing assessment of appropriate strategies in the biopharmaceutical industry to establish robust processes with optimized critical variables, that is, viable cell density (VCD) and specific productivity (product per cell, qP). Even though high VCD is a positive factor for titer, uncontrolled proliferation beyond a certain cell mass is also undesirable. To enable efficient process development to achieve consistent and predictable growth arrest while maintaining VCD, as well as improving qP, without negative impacts on product quality from clone to clone, we identified an approach that directly targets the cell cycle G1-checkpoint by selectively inhibiting the function of cyclin dependent kinases (CDK) 4/6 with a small molecule compound. Results from studies on multiple recombinant Chinese hamster ovary (CHO) cell lines demonstrate that the selective inhibitor can mediate a complete and sustained G0/G1 arrest without impacting G2/M phase. Cell proliferation is consistently and rapidly controlled in all recombinant cell lines at one concentration of this inhibitor throughout the production processes with specific productivities increased up to 110 pg/cell/day. Additionally, the product quality attributes of the mAb, with regard to high molecular weight (HMW) and glycan profile, are not negatively impacted. In fact, high mannose is decreased after treatment, which is in contrast to other established growth control methods such as reducing culture temperature. Microarray analysis showed major differences in expression of regulatory genes of the glycosylation and cell cycle signaling pathways between these different growth control methods. Overall, our observations showed that cell cycle arrest by directly targeting CDK4/6 using selective inhibitor compound can be utilized consistently and rapidly to optimize process parameters, such as cell growth, qP, and glycosylation profile in

7th Annual NASA/Contractors Conference on Quality and Productivity: "Total Quality Leadership"

Science.gov (United States)

1991-01-01

More than 750 NASA, government, contractor, and academic representatives attended the Seventh Annual NASA/Contractors Conference on Quality and Productivity on October 12-13, 1990, in Grenelefe, Florida. The panel presentations and keynote speeches revolving around the theme of 'Total Quality Leadership' provided a solid base of understanding of the importance, benefits, and principles of total quality management. The implementation of these strategies is critical if we are to effectively pursue our mission of continuous quality improvement and reliability in our products, processess, and services. The annual NASA/contractors conferences serve as catalysts for achieving success in this mission. The conference was highlighted by the announcement of the first recipients of the George M. Low Trophy: NASA's Quality and Excellence Award. My congratulations go out to all nine finalist organizations and to the two recipients of this prestigious honor: Rockwell Space Systems Division and Marotta Scientific Controls, Inc. (the first small business to achieve this honor). These organizations have demonstrated a commitment to quality that is unsurpassed in the aerospace industry. This report summarizes the presentations and is not intended to be a verbatim proceedings document. You are encouraged to contact the speakers with any requests for further information.

Production and quality of kefir cultured butter

Directory of Open Access Journals (Sweden)

Yaşar Karaca

2018-01-01

Full Text Available Cream is the main raw material for the butter production and reflects its properties into butter quality. Maturation of cream with appropriate starter culture is important for butter quality, sensory properties and shelf life of the end product. Kefir grains contain important probiotics for healthy nutrition including lactic acid bacteria, acetic acid bacteria, and yeasts in high numbers. The aim of this research was to determine the properties of butter produced using natural kefir culture during a 21-day cold storage. Determination of microbial, chemical and sensory properties of butter samples was carried out. Control sample (KOTE had 6.64 log CFU g-1 Lactococcus spp. while kefir cultured butter samples had 8.58 log CFU g-1. Kefir cultured butter contained 5.24 log CFU g-1 L. acidophilus at Day 1, while control samples did not have L. acidophilus. Acetaldehyde content of kefir cultured butter was significantly higher from the uncultured butter. According to sensory evaluation performed by 12 panelists, KKTE samples had better sensory properties than those observed in the KOTE samples.

[Update on microbiological quality assurance meat and meat products in Morocco].

Science.gov (United States)

Rachidi, H; Latrache, H

2018-03-01

Food safety has become an absolute necessity in all countries. As a result, Morocco has taken several measures and actions to develop food safety and food-borne disease control. This study aimed to highlight the level of improvement in the quality assurance of meat and meat products in Morocco. It is based on a non-exhaustive review of the regulatory texts governing food safety in the country, as well as a statistical study on establishments of meat and meat products adopting a self-checking system and approved by the National Office of Sanitary Safety of Food. Morocco has introduced several laws and regulations requiring sanitary control of food products. Also, the number of establishments of meat and meat products adopting a system of self-control and approved by the National Office of Sanitary Safety of Food has improved significantly. It has increased from 58 in 2007 to 273 in 2016. The adoption of self-monitoring systems allows better access to international markets, improved quality of food products and a considerable reduction in microbial contamination. Copyright © 2018 Elsevier Masson SAS. All rights reserved.

Water quality control program in experimental circuits

International Nuclear Information System (INIS)

Cegalla, Miriam A.

1996-01-01

The Water Quality Control Program of the Experimental Circuits visualizes studying the water chemistry of the cooling in the primary and secondary circuits, monitoring the corrosion of the systems and studying the mechanism of the corrosion products transport in the systems. (author)

Methods of Computational Intelligence in the Context of Quality Assurance in Foundry Products

Directory of Open Access Journals (Sweden)

Rojek G.

2016-06-01

Full Text Available One way to ensure the required technical characteristics of castings is the strict control of production parameters affecting the quality of the finished products. If the production process is improperly configured, the resulting defects in castings lead to huge losses. Therefore, from the point of view of economics, it is advisable to use the methods of computational intelligence in the field of quality assurance and adjustment of parameters of future production. At the same time, the development of knowledge in the field of metallurgy, aimed to raise the technical level and efficiency of the manufacture of foundry products, should be followed by the development of information systems to support production processes in order to improve their effectiveness and compliance with the increasingly more stringent requirements of ergonomics, occupational safety, environmental protection and quality. This article is a presentation of artificial intelligence methods used in practical applications related to quality assurance. The problem of control of the production process involves the use of tools such as the induction of decision trees, fuzzy logic, rough set theory, artificial neural networks or case-based reasoning.

Optimization of production and quality control of therapeutic radionuclides and radiopharmaceuticals. Final report of a co-ordinated research project 1994-1998

International Nuclear Information System (INIS)

1999-09-01

The 'renaissance' of the therapeutic applications of radiopharmaceuticals during the last few years was in part due to a greater availability of radionuclides with appropriate nuclear decay properties, as well as to the development of carrier molecules with improved characteristics. Although radionuclides such as 32 P, 89 Sr and 131 I, were used from the early days of nuclear medicine in the late 1930s and early 1940s, the inclusion of other particle emitting radionuclides into the nuclear medicine armamentarium was rather late. Only in the early 1980s did the specialized scientific literature start to show the potential for using other beta emitting nuclear reactor produced radionuclides such as 153 Sm, 166 Ho, 165 Dy and 186-188 Re. Bone seeking agents radiolabelled with the above mentioned beta emitting radionuclides demonstrated clear clinical potential in relieving intense bone pain resulting from metastases of the breast, prostate and lung of cancer patients. Therefore, upon the recommendation of a consultants meeting held in Vienna in 1993, the Co-ordinated Research Project (CRP) on Optimization of the Production and quality control of Radiotherapeutic Radionuclides and Radiopharmaceuticals was established in 1994. The CRP aimed at developing and improving existing laboratory protocols for the production of therapeutic radionuclides using existing nuclear research reactors including the corresponding radiolabelling, quality control procedures; and validation in experimental animals. With the participation of ten scientists from IAEA Member States, several laboratory procedures for preparation and quality control were developed, tested and assessed as potential therapeutic radiopharmaceuticals for bone pain palliation. In particular, the CRP optimised the reactor production of 153 Sm and the preparation of the radiopharmaceutical 153 Sm-EDTMP (ethylene diamine tetramethylene phosphonate), as well as radiolabelling techniques and quality control methods for

Pattern-based feature extraction for fault detection in quality relevant process control

NARCIS (Netherlands)

Peruzzo, S.; Holenderski, M.J.; Lukkien, J.J.

2017-01-01

Statistical quality control (SQC) applies multivariate statistics to monitor production processes over time and detect changes in their performance in terms of meeting specification limits on key product quality metrics. These limits are imposed by customers and typically assumed to be a single

Production of top quality soybean oil

Directory of Open Access Journals (Sweden)

Moustafa, Dr. Ahmad

1995-12-01

Full Text Available The paper comments the most adequate conditions required to produce to quality soybean oil. It is essential to avoid contaminations (water, metallic, oxidation products, overheating, undue exposition to air, as well as an appropriate control of the different steps of the refining process.

El trabajo presenta las condiciones recomendadas para obtener aceite de soja de la mejor calidad. Es importante evitar las contaminaciones (agua, metales y compuestos oxidados, los sobrecalentamientos, la exposición al aire, así como el adecuado control de los diferentes pasos del proceso de refinación.

Effective use of product quality information in food supply chain logistics

NARCIS (Netherlands)

Rijpkema, W.A.

2014-01-01

Food supply chains have inherent characteristics, such as variability in product quality and quality decay, which put specific demands on logistics decision making. Furthermore, food supply chain organization and control has changed significantly in the past decades by factors such as scale

Non-destructive evaluation methods to improve quality control in low enrichment MTR fuel plate production

International Nuclear Information System (INIS)

Milne, J.M.; Lidington, B.; Hawker, B.M.

1991-01-01

This paper summarises some preliminary non-destructive measurements made recently at the Harwell Laboratory on a prototype low enrichment MTR fuel plate. The measurements were intended to indicate the potential of two different techniques for improving quality control in plate production. Pulse Video Thermography (PVT) is being considered as an alternative to ultrasound transmission measurements for the detection and sizing of lack of thermal bonding between the fuel and the clad layers, either to verify the indications from the established ultrasonic methods before destroying the plate or as a replacement method of inspection. High frequency pulse-echo ultrasonics is being considered for providing maps of clad layer thickness on each side of the plate. The measurements have indicated the potential for both methods, but more work is required, using a test plate containing controlled defects, to establish their capability. (orig.)

USE OF INTELLECTUAL TECHNOLOGIES FOR QUALITY CONTROL OF CURD

Directory of Open Access Journals (Sweden)

M. M. Blagoveshchenskaia

2014-01-01

Full Text Available Summary. Method of curds quality control, based on neural network model is introduced in the paper. It allows to give fair estimate of final product’s quality without use of professional degustators. Method consists in construction of neural network model to estimate quality of curds by input and output parameters. Hardware software complex of curds taste control is proposed to apply in industry for independent estimate of final product. Operation of neural network model based on usage of artificial neural networks, which is one of directions of artificial intelligence theory. Neural network model consists of several artificial neurons layers, which emulate nerve cells functioning. Feed forward network of MLP type was used in solving of curds taste control problem. Feature of this network is that signals passed from one layer’s neurons to next layer’s neurons only from input layer to output, not the other way. Neural network was trained for its correct operation by selection of optimal synaptic factors. Flow diagram of training algorithm is introduced in the paper. Algorithm of neural network tuning is described in the paper. Author proposed set of recommendations for software-hardware complex deployment. Experiment results show that this taste estimate method based on neural net works simplify a problem of final product control as allow to react to deviations in production process on proper time.

Basic quality control in diagnostic radiology

International Nuclear Information System (INIS)

Wikstrom, Erik

2016-01-01

Along the route toward regular performance of Quality Control in the Diagnostic Imaging sector there are a number of balances to negotiate: Patient/Staff safety considerations vs Regulatory compliance vs Performance of modern equipment vs Clinic's Productivity. At first glance these ambitions may seem in conflict. The tests performed to meet regulatory requirements may or may not bear any semblance to real clinical measurement scenarios. And the process of collecting the data from the quality assurance tests may induce a system down- time that adversely affects the clinic's overall productivity. Furthermore, the time it takes to complete the analysis of the test data and provide the report required to take the facility back into operation is time wasted for patients waiting for a diagnostic imaging exam

21 CFR 226.40 - Production and control procedures.

Science.gov (United States)

2010-04-01

...) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR TYPE A MEDICATED ARTICLES Product Quality Control... event of any significant discrepancies, key personnel shall prevent distribution of the batch in... control procedures shall include provision for discontinuing distribution of any Type A medicated article...

Product control of radioactive waste

International Nuclear Information System (INIS)

Warnecke, E.; Giller, H.

1989-09-01

The aim of the seminar was to give a survey of product quality control and to find out whether the producers/conditioners of waste set and fulfil requirements for the quality of the waste. The program included the following main areas: Random sample tests; Container tests; Process qualification and inspection, and Inspections of waste from fuel element reprocessing abroad. In other lectures, there are reports on measures for producers of waste for guaranteeing the final storage requirements, on quality assurance measurements in the conditioning of waste from large research establishments and from fuel element manufacture. The calling up of waste containers and the documentation of waste data is also introduced. (orig./HP) [de

Resultados do controle de qualidade de produtos hemoderivados: análise sanitária Results of quality control of plasma derivatives products: sanitary analysis

Directory of Open Access Journals (Sweden)

Marisa C. Adati

2009-08-01

Full Text Available O Instituto Nacional de Controle de Qualidade em Saúde - INCQS, unidade técnico-científica da Fundação Oswaldo Cruz - Fiocruz, desempenha seu papel no controle de qualidade pericial, de bens e serviços sujeitos ao regime de Vigilância Sanitária, em particular medicamentos denominados de hemoderivados. Este trabalho fundamentou-se na análise de 3.100 lotes de hemoderivados, no período de janeiro de 2000 a dezembro de 2004, assim distribuídos: 31,6% (n=980 de albumina humana, 28,7% (n=890 de fator VIII, 21,4% (n=662 de imunoglobulina humana, 8,3% (n=257 de fator IX, 7,1% (n=220 de imunoglobulinas específicas como anti-Rho (D, antitetânica, anti-rábica, anti-Hepatite B e antivaricela zoster e 2,9% (n=91 de complexo protrombínico. As amostras foram recebidas para análise oriundas dos segmentos: portos, aeroportos e fronteiras de Brasília, Rio de Janeiro e São Paulo e de apreensões realizadas pelos estados de Pernambuco, Santa Catarina, Rio de Janeiro e Rio Grande do Sul. Quanto à modalidade de análise: 92,3% correspondem à análise controle, 5,9% fiscal, 1,4% orientação e 0,4% análise prévia. Da internalização dos hemoderivados importados: 40,0% ocorreram pelo aeroporto de Brasília, 26,9% por São Paulo e 25,2% pelo Rio de Janeiro. Concluindo, dos lotes de hemoderivados analisados, 99,1% apresentaram resultados satisfatórios e 0,9% foram insatisfatórios quanto ao ensaio de inspeção visual, solubilidade, ensaio de estabilidade e químico, e quanto ao teste de pirogênio e toxicidade inespecífica. Desta forma, monitorar a qualidade dos produtos hemoderivados é um instrumento fundamental no exercício das ações de Vigilância Sanitária.The technical scientific unit of the National Institute of Quality Control in Health (INCQS, part of the Oswaldo Cruz Foundation, has a role of investigational quality control of products and services related to health surveillance, in particular medicines denominated plasma

Linking quality goals and product development competences

DEFF Research Database (Denmark)

Olsen, Johanne Rønnow; Harmsen, Hanne; Friis, Alan

2008-01-01

Quality is a main determinant of consumer food choice. Product development is accordingly a key activity for companies, because it generates the products on the quality of which consumer choices are based. In this respect, product development managers have a focal role, as their personal quality......, including reversed laddering sessions with 18 product development managers. Discrepancies between managerial and consumer quality goals are uncovered. Furthermore, the results point to two general dilemmas faced by product development managers in relation to quality; an external stakeholder dilemma...... orientation influence the way product development is performed. The aim of this paper is to investigate managerial quality goals and how these may be linked to product development competences, which has not previously been studied. The study draws on an empirical, qualitative study in the Danish food industry...

Advanced methods of quality control in nuclear fuel fabrication

International Nuclear Information System (INIS)

Onoufriev, Vladimir

2004-01-01

Under pressure of current economic and electricity market situation utilities implement more demanding fuel utilization schemes including higher burn ups and thermal rates, longer fuel cycles and usage of Mo fuel. Therefore, fuel vendors have recently initiated new R and D programmes aimed at improving fuel quality, design and materials to produce robust and reliable fuel. In the beginning of commercial fuel fabrication, emphasis was given to advancements in Quality Control/Quality Assurance related mainly to product itself. During recent years, emphasis was transferred to improvements in process control and to implementation of overall Total Quality Management (TQM) programmes. In the area of fuel quality control, statistical control methods are now widely implemented replacing 100% inspection. This evolution, some practical examples and IAEA activities are described in the paper. The paper presents major findings of the latest IAEA Technical Meetings (TMs) and training courses in the area with emphasis on information received at the TM and training course held in 1999 and other latest publications to provide an overview of new developments in process/quality control, their implementation and results obtained including new approaches to QC

Microbiological quality control practices at Australian Radioisotopes

International Nuclear Information System (INIS)

Saunders, M.

1987-01-01

As a domestic manufacturer of therapeutic substances, Australian Radioisotopes (ARI) must adhere to guidelines set out by the Commonwealth Department of Health in the Code of Good Manufacturing Practices for Therapeutic Goods 1983 (GMP). The GMP gives guidelines for staff training, building requirements, sanitation, documentation and quality control practices. These guidelines form the basis for regular audits performed by officers of the National Biological Standards Laboratories. At Lucas Heights, ARI has combined the principles of the GMP with the overriding precautions introduced for environmental and staff safety and protection. Its policy is to maintain a high level of quality assurance for product identity, purity and sterility and apyrogenicity during all stages of product manufacture

Use of artificial intelligence in the production of high quality minced meat

Science.gov (United States)

Kapovsky, B. R.; Pchelkina, V. A.; Plyasheshnik, P. I.; Dydykin, A. S.; Lazarev, A. A.

2017-09-01

A design for an automatic line for minced meat production according to new production technology based on an innovative meat milling method is proposed. This method allows the necessary degree of raw material comminution at the stage of raw material preparation to be obtained, which leads to production intensification due to the traditional meat mass comminution equipment being unnecessary. To ensure consistent quality of the product obtained, the use of on-line automatic control of the technological process for minced meat production is envisaged. This system has been developed using artificial intelligence methods and technologies. The system is trainable during the operation process, adapts to changes in processed raw material characteristics and to external impacts that affect the system operation, and manufactures meat shavings with minimal dispersion of the typical particle size. The control system includes equipment for express analysis of the chemical composition of the minced meat and its temperature after comminution. In this case, the minced meat production process can be controlled strictly as a function of time, which excludes subjective factors for assessing the degree of finished product readiness. This will allow finished meat products with consistent, targeted high quality to be produced.

Automated quality control in a file-based broadcasting workflow

Science.gov (United States)

Zhang, Lina

2014-04-01

Benefit from the development of information and internet technologies, television broadcasting is transforming from inefficient tape-based production and distribution to integrated file-based workflows. However, no matter how many changes have took place, successful broadcasting still depends on the ability to deliver a consistent high quality signal to the audiences. After the transition from tape to file, traditional methods of manual quality control (QC) become inadequate, subjective, and inefficient. Based on China Central Television's full file-based workflow in the new site, this paper introduces an automated quality control test system for accurate detection of hidden troubles in media contents. It discusses the system framework and workflow control when the automated QC is added. It puts forward a QC criterion and brings forth a QC software followed this criterion. It also does some experiments on QC speed by adopting parallel processing and distributed computing. The performance of the test system shows that the adoption of automated QC can make the production effective and efficient, and help the station to achieve a competitive advantage in the media market.

Publications as an indicator of increased tobacco control research productivity (quantity and quality) in New Zealand.

Science.gov (United States)

Kira, Anette; Glover, Marewa; Bullen, Chris; Viehbeck, Sarah

2011-06-01

Tobacco control (TC) research capacity and productivity are critical for developing evidence-informed interventions that will reduce the harmful effects of smoking. The aim of this paper was to investigate New Zealand's (NZ) TC research capacity along with the quantity and quality of publications, following two government initiatives aimed, in part, at improving the quantity and quality of NZ TC research. Scopus was searched for articles with at least one NZ author and where the topic was of primary relevance to TC. Publications were organized into two time periods, following the government initiatives, 1993-2003 and 2004-2009. We analyzed the number of publications, publication journals, type of publications, impact (using the impact factor), and authorship. There has been an increase in number and impact of publications and number of authors. The number of publications has increased from an average of 14 (1994-2003) to 38 per year (2004-2009). The number of journals published increased from 64 to 86. The impact during 2004-2009 was almost threefold than in 1993-2003. The number of authors increased from 212 to 345, and the number of authors who had at least one first-authored publication increased from 80 to 124. These results show an encouraging trend in NZ TC research, with an increase in research productivity, quality, and in research capacity. It is possible that government-initiated and -funded infrastructural support contributed to increasing needed TC research, which supports the worth of such initiatives.

Principles and Practices for Quality Assurance and Quality Control

Science.gov (United States)

Jones, Berwyn E.

1999-01-01

Quality assurance and quality control are vital parts of highway runoff water-quality monitoring projects. To be effective, project quality assurance must address all aspects of the project, including project management responsibilities and resources, data quality objectives, sampling and analysis plans, data-collection protocols, data quality-control plans, data-assessment procedures and requirements, and project outputs. Quality control ensures that the data quality objectives are achieved as planned. The historical development and current state of the art of quality assurance and quality control concepts described in this report can be applied to evaluation of data from prior projects.

Quality Controlling CMIP datasets at GFDL

Science.gov (United States)

Horowitz, L. W.; Radhakrishnan, A.; Balaji, V.; Adcroft, A.; Krasting, J. P.; Nikonov, S.; Mason, E. E.; Schweitzer, R.; Nadeau, D.

2017-12-01

As GFDL makes the switch from model development to production in light of the Climate Model Intercomparison Project (CMIP), GFDL's efforts are shifted to testing and more importantly establishing guidelines and protocols for Quality Controlling and semi-automated data publishing. Every CMIP cycle introduces key challenges and the upcoming CMIP6 is no exception. The new CMIP experimental design comprises of multiple MIPs facilitating research in different focus areas. This paradigm has implications not only for the groups that develop the models and conduct the runs, but also for the groups that monitor, analyze and quality control the datasets before data publishing, before their knowledge makes its way into reports like the IPCC (Intergovernmental Panel on Climate Change) Assessment Reports. In this talk, we discuss some of the paths taken at GFDL to quality control the CMIP-ready datasets including: Jupyter notebooks, PrePARE, LAMP (Linux, Apache, MySQL, PHP/Python/Perl): technology-driven tracker system to monitor the status of experiments qualitatively and quantitatively, provide additional metadata and analysis services along with some in-built controlled-vocabulary validations in the workflow. In addition to this, we also discuss the integration of community-based model evaluation software (ESMValTool, PCMDI Metrics Package, and ILAMB) as part of our CMIP6 workflow.

Checking quality control?

DEFF Research Database (Denmark)

Brodersen, Lars

2005-01-01

How is quality control doing within the community of GIS, web-services based on geo-information, GI etc.?......How is quality control doing within the community of GIS, web-services based on geo-information, GI etc.?...

Improving Quality of Shoe Soles Product using Six Sigma

Science.gov (United States)

Jesslyn Wijaya, Athalia; Trusaji, Wildan; Akbar, Muhammad; Ma’ruf, Anas; Irianto, Dradjad

2018-03-01

A manufacture in Bandung produce kind of rubber-based product i.e. trim, rice rollers, shoe soles, etc. After penetrating the shoe soles market, the manufacture has met customer with tight quality control. Based on the past data, defect level of this product was 18.08% that caused the manufacture’s loss of time and money. Quality improvement effort was done using six sigma method that included phases of define, measure, analyse, improve, and control (DMAIC). In the design phase, the object’s problem and definition were defined. Delphi method was also used in this phase to identify critical factors. In the measure phase, the existing process stability and sigma quality level were measured. Fishbone diagram and failure mode and effect analysis (FMEA) were used in the next phase to analyse the root cause and determine the priority issues. Improve phase was done by designing alternative improvement strategy using 5W1H method. Some improvement efforts were identified, i.e. (i) modifying design of the hanging rack, (ii) create pantone colour book and check sheet, (iii) provide pedestrian line at compound department, (iv) buying stop watch, and (v) modifying shoe soles dies. Some control strategies for continuous improvement were proposed such as SOP or reward and punishment system.

Surface topography analysis for dimensional quality control of replication at the micrometre scale

DEFF Research Database (Denmark)

Balcon, M.; Marinello, F.; Tosello, Guido

2011-01-01

Replication of geometrical features and surfaces are present at different production levels, from realization of moulds to final product. Geometrical features must be reproduced within specification limits, to ensure product functionality . In order to control the replication quality, mould...... and replica surfaces must be quantitatively analysed and compared. In the present work, reference simulated surfaces were considered and studied in order to evaluate the effectiveness and traceability of different analysis tools for replication quality control. Topographies were analysed simulating different...

Quality control in the commerce of irradiated foods

International Nuclear Information System (INIS)

Bustos R, M.E.

2000-01-01

In spite of an irradiated food is innocuous for health and that the irradiation process offers great advantages as conservation and hygiene method and it has been recognised by the Agriculture and Health International organizations and although the adequate equipment exists to make this treatment in the majority of countries, an international trade of irradiated foods has not been established and it is that it has to be required that the quality control of the treatment should be regulated by the corresponding authorities and it also should be harmonized with other countries for the commercial interchange. Owing to up to present an identification method of irradiated foods which is validated, the unique quality control for irradiated foods is realized in the irradiation plant, measuring the absorbed dose in products, using dosimetric systems justly calibrated and standardized to be used the adequate for the type of product and dose level which is wanted to be measured for foods mainly for quarantine treatment which is very important to determine that any part of the irradiation system has reached the minimum dose to obtain the technical effect which is desired and that it does not exceed the maximum dose for that the product quality not to be altered. (Author)

Quality Control through Design and Process: Gambrel Roof Truss Challenge

Science.gov (United States)

Ward, Dell; Jones, James

2011-01-01

Customers determine whether a product fulfills their needs or satisfies them. "Quality control", then, is the process of finding out what the customer wants, along with designing, producing, delivering, and servicing the product--and ultimately satisfying the customer's expectations. For many years, people considered a product to be of good…

Quality Control Circles: A Vehicle for Just-in-Time Implementation.

Science.gov (United States)

Sepehri, Mehran

1985-01-01

Explains just-in-time (JIT) material flow and production, a method of production designed to eliminate waste. Discusses why quality control circles work so well with a JIT system, and describes how several companies have made JIT work for them. (CT)

Modern control of mineral wool production process

Directory of Open Access Journals (Sweden)

Stankov Stanko P.

2013-01-01

Full Text Available In this paper, the control of the plant for mineral wool production consisting of a number of the technological units of different sizes and complexity is considered. The application of modern equipment based on PLC (Programmable Logic Controller and SCADA (Supervisory Control And Data Acquisition configuration provides optimal control of technological process. Described supervisory and control system is consisting of a number of units doing decentralized distributed control of technological entities where all possible situation are considered during work of machines and devices, which are installed in electric drive and are protected from technological and electrical accident. Transformer station and diesel engine, raw materials transport and dosage, processes in dome oven, centrifuges, polycondensation (PC chamber, burners, compressor station, binder preparation and dosage, wool cutting, completed panel packing and their transport to storehouse are controlled. Process variables and parameters like as level, flow, velocity, temperature, pressure, etc. are controlled. Control system is doing identification of process states changes, diagnostic and prediction of errors and provides prediction of behavior of control objects when input flows of materials and generates optimal values of control variables due to decreasing downtime and technic - economical requires connected to wool quality to be achieved. Supervisory and control system either eliminates unwanted changes in the production line or restricts them within the allowable limits according to the technology. In this way, the optimization of energy and raw materials consumption and appropriate products quality is achieved, where requirements are satisfied in accordance with process safety and environmental standards. SCADA provides a visual representation of controlled and uncontrolled parts of the technological process, processing alarms and events, monitoring of the changes of relevant

Design for Limit Variability in Quality of Industrial Products: A Case ...

African Journals Online (AJOL)

The area under the normal curve of the distribution was evaluated as 0.94 falling within acceptable limit for processes in control. ... 0.76 while the probability of any sample observation being within the control limit is 0.94, showing that the process in control. Keywords: limit variability, quality of products, control limits, process

DETERMINANTS OF QUALITY MANAGEMENT PRACTICES IN STIMULATING PRODUCT AND PROCESS INNOVATIONS

Directory of Open Access Journals (Sweden)

Boris Urban

2017-12-01

Full Text Available Research highlights Quality Management System (QMS has now become a recognizable guarantee of trust in certified business systems. A critical review of the literature reveals that empirical studies conducted to date have yielded conflicting findings on the relationship between quality management practices and innovation. This study empirically investigates how quality management principles may act as determinants of product and process innovations. The results show that customer focus and leadership explain a significant amount of product innovation, but not process innovation. Empirical support also finds that people management explains a significant amount of variance in both product innovation and process innovation. The findings highlight the importance of developing formal organisational mechanisms to measure levels of such quality determinants as they are easily overlooked or taken for granted. Moreover, firms need to recognise that innovation is a multi-faceted concept that can be controlled from a process or a product perspective, a distinction which is sometimes blurred.

Preparation and quality control of technetium-99m radiopharmaceuticals

International Nuclear Information System (INIS)

Samuels, D.L.

1978-11-01

Appropriate procedures for the production and quality control of technetium-99m based radiopharmaceuticals in hospital radiopharmacy consistent with the recently published Australian Code of Good Manufacturing Practice are discussed

Quality control procedures for HTGR fuel element components

International Nuclear Information System (INIS)

Delle, W.W.; Koizlik, K.; Luhleich, H.; Nickel, H.

1976-08-01

The growing use of nuclear reactors for the production of electric power throughout the world, and the consequent increase in the number of nuclear fuel manufacturers, is giving enhanced importance to the consideration of quality assurance in the production of nuclear fuels. The fuel is the place, where the radioactive fission products are produced in the reactor and, therefore, the integrity of the fuel is of utmost importance. The first and most fundamental means of insuring that integrity is through the exercise of properly designed quality assurance programmes during the manufacture of the fuel and other fuel element components. The International Atomic Energy Agency therefore conducted an International Seminar on Nuclear Fuel Quality Assurance in Oslo, Norway from 24 till 28 May, 1976. This KFA report contains a paper which was distributed preliminary during the seminar and - in the second part - the text of the oral presentation. The paper gives a summary of the procedures available in the present state for the production control of HTGR core materials and of the meaning of the particular properties for reactor operation. (orig./UA) [de

Current quality assurance concepts and considerations for quality control of in-clinic biochemistry testing.

Science.gov (United States)

Lester, Sally; Harr, K E; Rishniw, Mark; Pion, Paul

2013-01-15

Quality assurance is an implied concept inherent in every consumer's purchase of a product or service. In laboratory testing, quality assurance encompasses preanalytic (sampling, transport, and handling prior to testing), analytic (measurement), and postanalytic (reporting and interpretation) factors. Quality-assurance programs require that procedures are in place to detect errors in all 3 components and that the procedures are characterized by both documentation and correction of errors. There are regulatory bodies that provide mandatory standards for and regulation of human medical laboratories. No such regulations exist for veterinary laboratory testing. The American Society for Veterinary Clinical Pathology (ASVCP) Quality Assurance and Laboratory Standards Committee was formed in 1996 in response to concerns of ASVCP members about quality assurance and quality control in laboratories performing veterinary testing. Guidelines for veterinary laboratory testing have been developed by the ASVCP. The purpose of this report was to provide an overview of selected quality-assurance concepts and to provide recommendations for quality control for in-clinic biochemistry testing in general veterinary practice.

Optimization of production and quality control of therapeutic radionuclides and radiopharmaceuticals. Final report of a co-ordinated research project 1994-1998

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-09-01

The `renaissance` of the therapeutic applications of radiopharmaceuticals during the last few years was in part due to a greater availability of radionuclides with appropriate nuclear decay properties, as well as to the development of carrier molecules with improved characteristics. Although radionuclides such as {sup 32}P, {sup 89}Sr and {sup 131}I, were used from the early days of nuclear medicine in the late 1930s and early 1940s, the inclusion of other particle emitting radionuclides into the nuclear medicine armamentarium was rather late. Only in the early 1980s did the specialized scientific literature start to show the potential for using other beta emitting nuclear reactor produced radionuclides such as {sup 153}Sm, {sup 166} Ho, {sup 165}Dy and {sup 186-188}Re. Bone seeking agents radiolabelled with the above mentioned beta emitting radionuclides demonstrated clear clinical potential in relieving intense bone pain resulting from metastases of the breast, prostate and lung of cancer patients. Therefore, upon the recommendation of a consultants meeting held in Vienna in 1993, the Co-ordinated Research Project (CRP) on Optimization of the Production and quality control of Radiotherapeutic Radionuclides and Radiopharmaceuticals was established in 1994. The CRP aimed at developing and improving existing laboratory protocols for the production of therapeutic radionuclides using existing nuclear research reactors including the corresponding radiolabelling, quality control procedures; and validation in experimental animals. With the participation of ten scientists from IAEA Member States, several laboratory procedures for preparation and quality control were developed, tested and assessed as potential therapeutic radiopharmaceuticals for bone pain palliation. In particular, the CRP optimised the reactor production of {sup 153}Sm and the preparation of the radiopharmaceutical {sup 153}Sm-EDTMP (ethylene diamine tetramethylene phosphonate), as well as radiolabelling

Mössbauer spectroscopy and quality control in ferrate technology

International Nuclear Information System (INIS)

Dedushenko, S. K.; Perfiliev, Yu. D.; Kulikov, L. A.

2013-01-01

This paper describes some prospective reactants for the ferrate technology of water treatment, the ways of their industrial production and the application of the Mössbauer spectroscopy for their quality control.

Quality control in the storage of potatoes for industrial processing

NARCIS (Netherlands)

Verdijck, G.J.C.; Tijskens, L.M.M.

2003-01-01

A novel control structure for a potato storage facility is presented that is directly geared at the optimal preservation of product quality. The quality of the stored potatoes is defined as frying colour that depends on sugar concentration. The optimal storage conditions are estimated using models

Quality control tests for the CMS Barrel RPCs

International Nuclear Information System (INIS)

Abbrescia, M.; Colaleo, A.; Guida, R.; Iaselli, G.; Loddo, F.; Maggi, M.; Marangelli, B.; Natali, S.; Nuzzo, S.; Pugliese, G.; Ranieri, A.; Romano, F.; Trentadue, R.; Cavallo, N.; Fabozzi, F.; Paolucci, P.; Piccolo, D.; Polese, G.; Sciacca, C.; Belli, G.; Necchi, M.; Ratti, S.P.; Riccardi, C.; Torre, P.; Vitulo, P.; Anguelov, T.; Genchev, V.; Panev, B.; Piperov, S.; Sultanov, G.; Vankov, P.; Dimitrov, A.; Litov, L.; Pavlov, B.; Petkov, P.

2006-01-01

An RPC based system will be employed for the CMS muon first level trigger. Severe quality controls and certification have been established all along the entire production chain. Procedures are briefly described and results for the acceptance percentage are given for the second part of the single gaps and double gaps production. Summary results are also reported for the full sets of tested chambers

IPOs and Product Quality.

OpenAIRE

Stoughton, Neal M; Wong, Kit Pong; Zechner, Josef

2001-01-01

Given recent public attention paid to high-flying Internet IPOs such as Yahoo and Amazon.com, we explore a product market motive for going public. We develop a model where consumers discern product quality from the stock price. The model predicts that only better-quality firms will go public. Effects of IPO announcements on rival firms' stock prices are related to inferences about market size and market share. The model also predicts that the likelihood of "hot issue" markets depends on the d...

Process-based quality for thermal spray via feedback control

Science.gov (United States)

Dykhuizen, R. C.; Neiser, R. A.

2006-09-01

Quality control of a thermal spray system manufacturing process is difficult due to the many input variables that need to be controlled. Great care must be taken to ensure that the process remains constant to obtain a consistent quality of the parts. Control is greatly complicated by the fact that measurement of particle velocities and temperatures is a noisy stochastic process. This article illustrates the application of quality control concepts to a wire flame spray process. A central feature of the real-time control system is an automatic feedback control scheme that provides fine adjustments to ensure that uncontrolled variations are accommodated. It is shown how the control vectors can be constructed from simple process maps to independently control particle velocity and temperature. This control scheme is shown to perform well in a real production environment. We also demonstrate that slight variations in the feed wire curvature can greatly influence the process. Finally, the geometry of the spray system and sensor must remain constant for the best reproducibility.

Quality control of intelligence research

International Nuclear Information System (INIS)

Lu Yan; Xin Pingping; Wu Jian

2014-01-01

Quality control of intelligence research is the core issue of intelligence management, is a problem in study of information science This paper focuses on the performance of intelligence to explain the significance of intelligence research quality control. In summing up the results of the study on the basis of the analysis, discusses quality control methods in intelligence research, introduces the experience of foreign intelligence research quality control, proposes some recommendations to improve quality control in intelligence research. (authors)

Advanced process monitoring and feedback control to enhance cell culture process production and robustness.

Science.gov (United States)

Zhang, An; Tsang, Valerie Liu; Moore, Brandon; Shen, Vivian; Huang, Yao-Ming; Kshirsagar, Rashmi; Ryll, Thomas

2015-12-01

It is a common practice in biotherapeutic manufacturing to define a fixed-volume feed strategy for nutrient feeds, based on historical cell demand. However, once the feed volumes are defined, they are inflexible to batch-to-batch variations in cell growth and physiology and can lead to inconsistent productivity and product quality. In an effort to control critical quality attributes and to apply process analytical technology (PAT), a fully automated cell culture feedback control system has been explored in three different applications. The first study illustrates that frequent monitoring and automatically controlling the complex feed based on a surrogate (glutamate) level improved protein production. More importantly, the resulting feed strategy was translated into a manufacturing-friendly manual feed strategy without impact on product quality. The second study demonstrates the improved process robustness of an automated feed strategy based on online bio-capacitance measurements for cell growth. In the third study, glucose and lactate concentrations were measured online and were used to automatically control the glucose feed, which in turn changed lactate metabolism. These studies suggest that the auto-feedback control system has the potential to significantly increase productivity and improve robustness in manufacturing, with the goal of ensuring process performance and product quality consistency. © 2015 Wiley Periodicals, Inc.

INSURANCE OF KNITTED PRODUCTS QUALITY THROUGH THE ANALYSIS AND EVALUATION OF NON-QUALITY DURING THE OPERATIONS IN THE CUTTING ROOM

Directory of Open Access Journals (Sweden)

LUTIC Liliana

2014-05-01

Full Text Available n a knitting- confection profile factory, any activity oriented toward evaluation, maintenance or improvement of products quality level is based on measuring and examining the product quality characteristics, in order to establish conformity to the quality specifications and/or naming the non-quality characteristics (establishing defects and fabrication deficiencies. We can consider non-quality as complementary to quality, although a definitive distinction cannot always be made between the two categories or states. Cutting holds a key role in insuring shape precision and pieces dimensions, determining the quality of the confection process, its structure and manual stages frequency. The quality of the cutting operation, appreciated through the precision and aspect of cut contours, existence and precision of markings, is directly reflected in the finite product’s quality, which entails knowledge of cutting instrument - fabric interactions. In compliance of the technological regime during the operations in the cutting room can determine: incorrect marking, spreading, sectioning or cutting. Non-quality of intermediate products obtained in the cutting department can be evaluated and controlled through defectologic control methods.The De – Ca – Re method (defect-cause-remedy correlation, applied in this paper, allows establishing the most important causes that generate defects, as well as preventive and corrective actions to eliminate these causes. This paper systematically presents the main defects that may occur during operations in the cutting room, causes that generate these defects, along with their preventive and corrective actions.

Dual substrate feedback control of specific growth-rate in vaccine production

NARCIS (Netherlands)

Neeleman, R.; Beuvery, E.C.; Vries, D.; Straten, van G.; Boxtel, van A.J.B.

2004-01-01

Abstract: Unexpectedly, primary concern of bio-pharmaceutical industry is not optimisation of product yield or cost reduction, but consistency in production and product quality. This paper describes the methodology and experimental results of specific growth-rate control for vaccine production. The

Product quality of parenteral vancomycin products in the United States.

Science.gov (United States)

Nambiar, S; Madurawe, R D; Zuk, S M; Khan, S R; Ellison, C D; Faustino, P J; Mans, D J; Trehy, M L; Hadwiger, M E; Boyne, M T; Biswas, K; Cox, E M

2012-06-01

In response to concerns raised about the quality of parenteral vancomycin products, the U.S. Food and Drug Administration (FDA) is investigating the product quality of all FDA-approved parenteral vancomycin products available in the United States. Product quality was evaluated independently at two FDA Office of Testing and Research (FDA-OTR) sites. In the next phase of the investigation, being done in collaboration with the National Institute of Allergy and Infectious Diseases, the in vivo activity of these products will be evaluated in an appropriate animal model. This paper summarizes results of the FDA investigation completed thus far. One site used a validated ultrahigh-pressure liquid chromatography method (OTR-UPLC), and the second site used the high-performance liquid chromatography (HPLC) method for related substances provided in the British Pharmacopeia (BP) monograph for vancomycin intravenous infusion. Similar results were obtained by the two FDA-OTR laboratories using two different analytical methods. The products tested had 90 to 95% vancomycin B (active component of vancomycin) by the BP-HPLC method and 89 to 94% vancomycin by OTR-UPLC methods. Total impurities were 5 to 10% by BP-HPLC and 6 to 11% by OTR-UPLC methods. No single impurity was >2.0%, and the CDP-1 level was ≤ 2.0% across all products. Some variability in impurity profiles of the various products was observed. No adverse product quality issues were identified with the six U.S. vancomycin parenteral products. The quality parameters of all parenteral vancomycin products tested surpassed the United States Pharmacopeia acceptance criteria. Additional testing will characterize in vivo performance characteristics of these products.

Quality control in radiotherapy

International Nuclear Information System (INIS)

Batalla, A.

2009-01-01

The authors discuss the modalities and periodicities of internal quality control on radiotherapy installations. They indicate the different concerned systems and the aspects and items to be controlled (patient and personnel security, apparatus mechanical characteristics, beam quality, image quality, isodose and irradiation duration calculation, data transfer). They present the measurement instruments and tools used for the mechanical controls, dose measurement, beam homogeneity and symmetry, anatomic data acquisition systems, and dose distribution and control imagery calculation

Quality assurance and control in constructing the Dukovany nuclear power plant

International Nuclear Information System (INIS)

Lujka, T.

1986-01-01

A quality control and assurance department was established on the Dukovany nuclear power plant site as a unit independent of the production divisions of the plant. Its responsibility consists in testing activities including the development of testing techniques and cooperation in the compilation of specifications and binding technological regulations. The department consists of five sections. The concrete laying laboratory has a staff of 7 and concentrates on testing the quality of concrete mixes and their components in the central concrete production plant. The materials testing centre with a staff of 5 provides testing of steel and special structures and oversees the laying of heavy and very heavy concretes. A separate unit for the testing of surface finish of building structures is staffed with 4 people. The section of technological checks of building and assembly work with a staff of 4 is responsible for the quality of work in the main production unit zone but also of the other buildings on the site. Two people staff the unit for checking and filing the quality control documents for selected components. (Z.M.)

Nuclear-derived techniques improve cattle productivity and milk quality in Cameroon

International Nuclear Information System (INIS)

Dixit, Aabha

2016-01-01

Increasing agricultural production and improving the quality of milk and meat are key to combating poverty and increasing food security in Africa. Countries such as Cameroon are increasingly turning to innovative, nuclear and nuclear-derived techniques to control and prevent diseases among livestock, and boost cattle and milk production.

21 CFR 111.113 - What quality control operations are required for a material review and disposition decision?

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What quality control operations are required for a... Production and Process Control System: Requirements for Quality Control § 111.113 What quality control operations are required for a material review and disposition decision? (a) Quality control personnel must...

CryoSat data quality assessment and product evolutions

Science.gov (United States)

Bouffard, Jerome; Femenias, Pierre; Parrinello, Tommaso; Fornari, Marco; Brockley, David; Scagliola, Michele; Calafat, Francisco; Roca, Monica

2015-04-01

The main payload of the ESA Earth Explorer CryoSat satellite is a Ku band pulse-width limited radar altimeter, operating in 3 different modes function of a mask of geographical zones. Over the ocean and ice sheet interiors, CryoSat mainly operates like a conventional pulse-limited radar altimeter whereas over sea ice, coherently transmitted echoes are combined in order to carry out measurements at a higher resolution. Around ice sheet margins, a 2nd antenna is used as an interferometer in order to determine the across-track angle to the earliest radar returns. Two kinds of data are distributed to the scientific user community and are quality controlled and validated by ESA/ESRIN SPPA office with the support of an industrial consortium: the Level 1b products essentially contain average echoes collected along the ground track while the Level 2 products contain elevations and associated geophysical parameters retrieved from these echoes. In this poster we first briefly present the characteristics of Level 1b and Level 2 CryoSat products over ocean, land ice and sea ice in addition to the results of recent quality control activities. Due to anomalies detected in previous data release and the need of continuously improving the data quality, ESA and its industrial partners has implemented a new version of the processors by the early of 2015, followed by a full reprocessing campaign. The main evolutions of this so called "Baseline C", the validation of the associated Test Data Set and the main improvements expected from this new release are also presented.

Express quality control of chicken eggs by machine vision

Science.gov (United States)

Gorbunova, Elena V.; Chertov, Aleksandr N.; Peretyagin, Vladimir S.; Korotaev, Valery V.; Arbuzova, Evgeniia A.

2017-06-01

The urgency of the task of analyzing the foodstuffs quality is determined by the strategy for the formation of a healthy lifestyle and the rational nutrition of the world population. This applies to products, such as chicken eggs. In particular, it is necessary to control the chicken eggs quality at the farm production prior to incubation in order to eliminate the possible hereditary diseases, as well as high embryonic mortality and a sharp decrease in the quality of the bred young. Up to this day, in the market there are no objective instruments of contactless express quality control as analytical equipment that allow the high-precision quality examination of the chicken eggs, which is determined by the color parameters of the eggshell (color uniformity) and yolk of eggs, and by the presence in the eggshell of various defects (cracks, growths, wrinkles, dirty). All mentioned features are usually evaluated only visually (subjectively) with the help of normalized color standards and ovoscopes. Therefore, this work is devoted to the investigation of the application opportunities of contactless express control method with the help of technical vision to implement the chicken eggs' quality analysis. As a result of the studies, a prototype with the appropriate software was proposed. Experimental studies of this equipment on a representative sample of eggs from chickens of different breeds have been carried out (the total number of analyzed samples exceeds 300 pieces). The correctness of the color analysis was verified by spectrophotometric studies of the surface of the eggshell.

QUALITY OF VOCATIONAL TRAINING THROUGH PRODUCT LIFECYCLE MANAGEMENT INSTRUMENTS

Directory of Open Access Journals (Sweden)

Carmen\tCHAŞOVSCHI

2015-12-01

Full Text Available It appears that, during the process of continuous training, there is a growing need from VET providers of a reliable and easy to use tool ensuring the quality of the services provided. Product life cycle active management, including the use of suitable PLM software, is or may be a tool for monitoring and controlling product portfolio of an educational institution. It can be recommended not only for reasons of quality assurance, but also to facilitate the development of products for greater transparency in strategic business areas, and not least, to maintain competitiveness of VET providers. The Q-PLM project analysed the core of the product life cycle management in other sectors, identified the relevant variables that have an impact on the life cycle of VET provision and, on this basis, developed the beta version of a IT tool (software for product life cycle management addressed to VET providers, and a user manual for product life cycle management. The Q-PLM software makes possible the identification of the training products lifecycle, the life cycle stages, the key success factors and indicators for the training products lifecycle, separately for each training program and for each college.

Information system of quality assessment for liquid and gaseous medium production

Science.gov (United States)

Bobrov, V. N.; Us, N. A.; Davidov, I. S.

2018-05-01

A method and a technical solution for controlling the quality of production of liquid and gaseous media is proposed. It is also proposed to monitor harmful factors in production while ensuring safe working conditions. Initially, using the mathematical model of an ideal atmosphere, the projection to the horizontal surface of the observation trajectory is calculated. At the second stage, the horizontal projection of the observation trajectory in real conditions is measured. The quality of the medium is judged by the difference between the projections of observation trajectories. The technical result is presented in the form of a device allowing obtaining information about the quality of the medium under investigation.

HPTLC Fingerprint Analysis: A Quality Control for Authentication of Herbal Phytochemicals

Science.gov (United States)

Ram, Mauji; Abdin, M. Z.; Khan, M. A.; Jha, Prabhakar

Authentication and consistent quality are the basic requirement for Indian traditional medicine (TIM), Chinese traditional herbal medicine (TCHM), and their commercial products, regardless of the kind of research conducted to modernize the TIM and TCHM. The complexities of TIM and TCHM challenge the current official quality control mode, for which only a few biochemical markers were selected for identification and quantitative assay. Referring too many unknown factors existed in TIM and TCHM, it is impossible and unnecessary to pinpoint qualitatively and quantitatively every single component contained in the herbal drug. Chromatographic fingerprint is a rational option to meet the need for more effective and powerful quality assessment to TIM and TCHM. The optimized chromatographic fingerprint is not only an alternative analytical tool for authentication, but also an approach to express the various pattern of chemical ingredients distribution in the herbal drugs and preserve such "database" for further multifaced sustainable studies. Analytical separation techniques, for example, high-performance liquid chromatography (HPLC), gas chromatography (GC) and mass spectrometry (MS) were among the most popular methods of choice used for quality control of raw material and finished herbal product. Fingerprint analysis approach using high-performance thin-layer chromatography (HPTLC) has become the most potent tool for quality control of herbal medicines because of its simplicity and reliability. It can serve as a tool for identification, authentication, and quality control of herbal drugs. In this chapter, attempts are being made to expand the use of HPTLC and at the same time create interest among prospective researcher in herbal analysis. The developed method can be used as a quality control tool for rapid authentication from a wide variety of herbal samples. Some examples demonstrated the role of fingerprinting in quality control and assessment.

Quality control in food irradiated with gamma radiations from Cobalt 60

International Nuclear Information System (INIS)

Bustos R, M.E.

1993-01-01

The quality control of irradiated food can only be carry out in the irradiation plant by means of the measurement of the absorbed dose by the product, since to day there is not exist a technique which allows to demonstrate that a food has been irradiated. Dosemeters are materials or devices which measure the absorbed dose by the product during the irradiation time. The type of the dosemeter is a choice as a function of factors as the range of dose for to reach of the desired technical purpose, the cost, the handling facility (handy) and its availability. The correct measurements of dose and dose distribution permits to indicate that the irradiation process is safe, effective and legally correct. The food quality after the irradiation is analyzed on basis and tests already established for a specific product: such tests can be sensory, chemical, physical or physiological> The quality control of the irradiation food is an important information for the consumer who wishes to know the food value and hygienic properties of the product. (Author)

Multicapillary SDS-gel electrophoresis for the analysis of fluorescently labeled mAb preparations: a high throughput quality control process for the production of QuantiPlasma and PlasmaScan mAb libraries.

Science.gov (United States)

Székely, Andrea; Szekrényes, Akos; Kerékgyártó, Márta; Balogh, Attila; Kádas, János; Lázár, József; Guttman, András; Kurucz, István; Takács, László

2014-08-01

Molecular heterogeneity of mAb preparations is the result of various co- and post-translational modifications and to contaminants related to the production process. Changes in molecular composition results in alterations of functional performance, therefore quality control and validation of therapeutic or diagnostic protein products is essential. A special case is the consistent production of mAb libraries (QuantiPlasma™ and PlasmaScan™) for proteome profiling, quality control of which represents a challenge because of high number of mAbs (>1000). Here, we devise a generally applicable multicapillary SDS-gel electrophoresis process for the analysis of fluorescently labeled mAb preparations for the high throughput quality control of mAbs of the QuantiPlasma™ and PlasmaScan™ libraries. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

42 CFR 84.41 - Quality control plans; contents.

Science.gov (United States)

2010-10-01

... organizational structure necessary to carry out these provisions. (b) Each provision for incoming and final... ensure control of product quality through the manufacturing cycle. (c) The sampling procedure shall... experience indicate is likely to result in a condition immediately hazardous to life or health for...

Specific MRI quality control: development and production of a multimodal test-object. Assessment of MRI sequences

International Nuclear Information System (INIS)

Dedieu, Veronique; Bard, Jean-Jacques; Bonnet, Jacques; Buchheit, Isabelle; Confort-Gouny, Sylviane; Certaines, Jacques de; Lacaze, Brigitte; Vincensini, Dominique; Joffre, Francis

2007-02-01

After a first part recalling the operation principle of a MRI imager and the modalities of acquisition of MRI images (base MNR experiment, image quality, technical issues, artefacts and main defects of MRI imagers), this document addresses the different types of quality control in MRI and regulatory issues. The third part presents the characteristics of a multimodal test-object which has been developed, the parameters of the specific quality control, and control procedures

Effect of superdosing phytase on productive performance and egg quality in laying hens

Directory of Open Access Journals (Sweden)

Jong Hyuk Kim

2017-07-01

Full Text Available Objective An experiment was conducted to determine the effect of superdosing phytase on productive performance and egg quality in laying hens. Methods A total of 200 42-wk-old Hy-Line Brown laying hens were allotted into 1 of 5 dietary treatments with 5 replicates consisting of 8 hens per replicate. The positive control (PC and negative control diets (NC were prepared based on the recommended P levels in layer diets. Supplemental phytase was added to the negative control diet at 10,000 (SD10, 20,000 (SD20, or 30,000 (SD30 fytase units (FTU/kg. Productive performance was summarized for 6 weeks from 42 weeks to 47 weeks of age. Egg quality was assessed from 4 eggs per replicate randomly collected at the conclusion of the experiment. Results The SD20 treatment had greater (p<0.05 hen-day egg production than PC, NC, and SD10 treatment groups. There was no difference in hen-day egg production between SD20 and SD30 treatment groups. However, SD30 treatment had greater (p<0.05 hen-day egg production than PC treatment, but showed no difference in hen-day egg production as compared to NC and SD10 treatment groups. However, egg weight, egg mass, feed intake, and feed conversion ratio were not affected by dietary treatments. Egg quality including eggshell strength, eggshell color, egg yolk color, and haugh unit was not influenced by dietary treatments. Conclusion Superdosing level of 20,000 FTU/kg phytase in diets has a positive effect on egg production rate, but no beneficial effect on egg quality in laying hens.

Mechanics of human voice production and control.

Science.gov (United States)

Zhang, Zhaoyan

2016-10-01

As the primary means of communication, voice plays an important role in daily life. Voice also conveys personal information such as social status, personal traits, and the emotional state of the speaker. Mechanically, voice production involves complex fluid-structure interaction within the glottis and its control by laryngeal muscle activation. An important goal of voice research is to establish a causal theory linking voice physiology and biomechanics to how speakers use and control voice to communicate meaning and personal information. Establishing such a causal theory has important implications for clinical voice management, voice training, and many speech technology applications. This paper provides a review of voice physiology and biomechanics, the physics of vocal fold vibration and sound production, and laryngeal muscular control of the fundamental frequency of voice, vocal intensity, and voice quality. Current efforts to develop mechanical and computational models of voice production are also critically reviewed. Finally, issues and future challenges in developing a causal theory of voice production and perception are discussed.

Quality assurance and quality control

International Nuclear Information System (INIS)

Anon.

1987-01-01

The practice of nuclear diagnostic imaging requires an appropriate quality assurance program to attain high standards of efficiency and reliability. The International Atomic Energy Agency defines the term quality assurance as ''the closeness with which the outcome of a given procedure approaches some ideal, free from all errors and artifacts.'' The term quality control is used in reference to the specific measures taken to ensure that one particular aspect of the procedure is satisfactory. Therefore, quality assurance is a hospital-wide concept that should involve all aspects of clinical practice. Quality control is concerned with the submission of requests for procedures; the scheduling of patients; the preparation and dispensing of radiopharmaceuticals; the protection of patients, staff, and the general public against radiation hazards and accidents caused by radioactive materials or by faulty equipment; the setting up, use, and maintenance of electronic instruments; the methodology of the actual procedures; the analysis and interpretation of data; the reporting of results; and, finally, the keeping of records. The chapter discusses each of these areas

Use of statistical process control in the production of blood components

DEFF Research Database (Denmark)

Magnussen, K.; Quere, S.; Winkel, P.

2008-01-01

occasional component manufacturing staff to an experienced regular manufacturing staff. Production of blood products is a semi-automated process in which the manual steps may be difficult to control. This study was performed in an ongoing effort to improve the control and optimize the quality of the blood...

Quality control related to total quality: why not to nuclear area too?

International Nuclear Information System (INIS)

Vasques, R.J.

1992-01-01

We're living in a new economical age, where quality, productivity, competence, competitiveness and costumer satisfaction are necessary. We must develop our capacity more and more, daily, for could survive and to excel in this new age. Only through Total Quality Control (TQC) is that we'll go to achieve these requirements. TQC is expanding all over the world and is already, the new universal language. Why not get the TQC's benefits to nuclear area too? We must stay within this reality. With our quality assurance systems turned to TQC, certainly we'll get best results. This is the intention of this paper: to call the nuclear professionals attention to knowledge, application and commitment to TQC's philosophy. (author)

Physical chemical quality control of the molybdenum technetium generator

International Nuclear Information System (INIS)

Olive, E.; Cruz, J.; Isaac, M.; Gamboa, R.; D'Alessandro, K.; Desdin, L.F.

1995-01-01

Comparative operational procedure imported molybdenum technetium generators have been made. Procedures for determination of chemical, radiochemical and radionuclidic purities that may be applied in Hospital's laboratories and in the quality control of generators production are developed

Influence of raw milk quality on processed dairy products: How do raw milk quality test results relate to product quality and yield?

Science.gov (United States)

Murphy, Steven C; Martin, Nicole H; Barbano, David M; Wiedmann, Martin

2016-12-01

This article provides an overview of the influence of raw milk quality on the quality of processed dairy products and offers a perspective on the merits of investing in quality. Dairy farmers are frequently offered monetary premium incentives to provide high-quality milk to processors. These incentives are most often based on raw milk somatic cell and bacteria count levels well below the regulatory public health-based limits. Justification for these incentive payments can be based on improved processed product quality and manufacturing efficiencies that provide the processor with a return on their investment for high-quality raw milk. In some cases, this return on investment is difficult to measure. Raw milks with high levels of somatic cells and bacteria are associated with increased enzyme activity that can result in product defects. Use of raw milk with somatic cell counts >100,000cells/mL has been shown to reduce cheese yields, and higher levels, generally >400,000 cells/mL, have been associated with textural and flavor defects in cheese and other products. Although most research indicates that fairly high total bacteria counts (>1,000,000 cfu/mL) in raw milk are needed to cause defects in most processed dairy products, receiving high-quality milk from the farm allows some flexibility for handling raw milk, which can increase efficiencies and reduce the risk of raw milk reaching bacterial levels of concern. Monitoring total bacterial numbers in regard to raw milk quality is imperative, but determining levels of specific types of bacteria present has gained increasing importance. For example, spores of certain spore-forming bacteria present in raw milk at very low levels (e.g., products to levels that result in defects. With the exception of meeting product specifications often required for milk powders, testing for specific spore-forming groups is currently not used in quality incentive programs in the United States but is used in other countries (e.g., the

Metrological aspects to quality control for natural gas analyses

Energy Technology Data Exchange (ETDEWEB)

Ribeiro, Claudia Cipriano; Borges, Cleber Nogueira; Cunha, Valnei S. [Instituto Nacional de Metrologia, Normalizacao e Qualidade Industrial (INMETRO), Rio de Janeiro, RJ (Brazil); Augusto, Cristiane R. [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil); Augusto, Marco Ignazio [Companhia Estadual de Gas do Rio de Janeiro (CEG), RJ (Brazil)

2008-07-01

The Product's Quality and Services are fundamental topics in the globalized commercial relationship inclusive concern the measurements in natural gas. Considerable investments were necessary for industry especially about the quality control in the commercialized gas with an inclusion of the natural gas in Brazilian energetic resources The Brazilian Regulatory Agency, ANP - Agencia Nacional de Petroleo, Gas Natural e Biocombustiveis - created the Resolution ANP no.16. This Resolution defines the natural gas specification, either national or international source, for commercialization in Brazil and list the tolerance concentration for some components. Between of this components are the inert compounds like the CO{sub 2} and N{sub 2}. The presence of this compounds reduce the calorific power, apart from increase the resistance concern the detonation in the case of vehicular application, and occasion the reduction in the methane concentration in the gas. Controls charts can be useful to verify if the process are or not under Statistical Control. The process can be considerate under statistical control if the measurements have it values between in lower and upper limits stated previously The controls charts can be approach several characteristics in each subgroup: means, standard deviations, amplitude or proportion of defects. The charts are draws for a specific characteristic and to detect some deviate in the process under specific environment conditions. The CEG - Companhia de Distribuicao de Gas do Rio de Janeiro and the DQUIM - Chemical Metrology Division has an agreement for technical cooperation in research and development of gas natural composition Concern the importance of the natural gas in the Nation development, as well as the question approaching the custody transference, the objective of this work is demonstrate the control quality of the natural gas composition between the CEG laboratory and the DQUIM laboratory aiming the quality increase of the

Production controls (PC) and technical verification testing (TVT). A methodology for the control and tracking of LILW waste package conditioning

International Nuclear Information System (INIS)

Leon, A.M.; Nieto, J.L.L.; Garrido, J.G.

2003-01-01

As part of its low and intermediate level radioactive waste (LILW) characterisation and acceptance activities, ENRESA has set up a quality control programme that covers the different phases of radioactive waste package production and implies different levels of tracking in generation, assessment of activity and control of the documentation associated therewith. Furthermore, ENRESA has made available the mechanisms required for verification, depending on the results of periodic sampling, of the quality of the end product delivered by the waste producers. Both processes are included within the framework of two programmes of complementary activities: production controls (PC) and technical verification testing (TVT). (orig.)

The Dynamic Signification of Product Qualities

DEFF Research Database (Denmark)

Reijonen, Satu; Tryggestad, Kjell

2012-01-01

This article addresses the “greening” of markets by inquiring into how different versions of environmental friendliness of a product are constructed and how they are placed in an order of significance in relation to each other and to other product qualities. The study extends constructivist market...... studies by elaborating on the dynamic signification of product qualities. The case analysis of the development and commercialization of a “polyvinylchloride-free” and “environmentally friendly” urinary drainage bag in the medical devices market shows these qualities to be temporal and fragile outcomes....... It is concluded that, besides a supporting socio-technical market arrangement around the product, the ability of the product to take different matters of concern into account is crucial for the possibility of “greening” markets....

Implementation of quality by design toward processing of food products.

Science.gov (United States)

Rathore, Anurag S; Kapoor, Gautam

2017-05-28

Quality by design (QbD) is a systematic approach that begins with predefined objectives and emphasizes product and process understanding and process control. It is an approach based on principles of sound science and quality risk management. As the food processing industry continues to embrace the idea of in-line, online, and/or at-line sensors and real-time characterization for process monitoring and control, the existing gaps with regard to our ability to monitor multiple parameters/variables associated with the manufacturing process will be alleviated over time. Investments made for development of tools and approaches that facilitate high-throughput analytical and process development, process analytical technology, design of experiments, risk analysis, knowledge management, and enhancement of process/product understanding would pave way for operational and economic benefits later in the commercialization process and across other product pipelines. This article aims to achieve two major objectives. First, to review the progress that has been made in the recent years on the topic of QbD implementation in processing of food products and second, present a case study that illustrates benefits of such QbD implementation.

Quality determinants of fruit and vegetables productions

Directory of Open Access Journals (Sweden)

Bruno Mezzetti

2009-04-01

Full Text Available Nowadays, the main goal for modern horticultural production is the increase of quality. Furthermore, in consideration of the new consumer demand, always more attracted by a diet based on a larger consumption of fruit and vegetables without risks of pesticides residues and with increased nutritional value, new important features in addition to the traditional quality attributes are now requested. For a program of qualification and valorisation of modern horticultural productions, it is fundamental a study of the major quality determinants organized by following a heuristic approache useful to identify the contribution of each factor in defining the quality of the product. The genetic knowledge applied to all available techniques useful for the creation of new genetic variability surely represent the most important starting point for the release of new varieties with increased nutritional quality without limitation in plant productivity. About agronomic practices, new opportunities are offered by the sustainable management of the production factors able to improve the plant-environment interaction, to well address the reduction of inputs needed for the production, and finally to induce specific stress conditions able to promote higher quality at reduced inputs. Much more attention is also addressed to the post-harvest technologies, this because of the increased needs to guarantee the preservation of the high quality obtained in the field until the consumer use. Taking in account such complexity of the horticultural production systems and examples of some major model crops, an outlook of the main determinants and potential valorisation of high quality horticultural products are attempted.

Quality determinants of fruit and vegetables productions

Directory of Open Access Journals (Sweden)

Bruno Mezzetti

Full Text Available Nowadays, the main goal for modern horticultural production is the increase of quality. Furthermore, in consideration of the new consumer demand, always more attracted by a diet based on a larger consumption of fruit and vegetables without risks of pesticides residues and with increased nutritional value, new important features in addition to the traditional quality attributes are now requested. For a program of qualification and valorisation of modern horticultural productions, it is fundamental a study of the major quality determinants organized by following a heuristic approache useful to identify the contribution of each factor in defining the quality of the product. The genetic knowledge applied to all available techniques useful for the creation of new genetic variability surely represent the most important starting point for the release of new varieties with increased nutritional quality without limitation in plant productivity. About agronomic practices, new opportunities are offered by the sustainable management of the production factors able to improve the plant-environment interaction, to well address the reduction of inputs needed for the production, and finally to induce specific stress conditions able to promote higher quality at reduced inputs. Much more attention is also addressed to the post-harvest technologies, this because of the increased needs to guarantee the preservation of the high quality obtained in the field until the consumer use. Taking in account such complexity of the horticultural production systems and examples of some major model crops, an outlook of the main determinants and potential valorisation of high quality horticultural products are attempted.

MICROBIOLOGICAL QUALITY OF CONFECTIONARY PRODUCTS

Directory of Open Access Journals (Sweden)

Ľubomíra Juhaniaková

2013-02-01

Full Text Available The aim of this work was to determine microbiological quality of confectionery products. In confectionery products microbiological parameters: total count of bacteria, coliforms bacteria,mesophilic aerobes bacteria and microscopic filamentous fungi were observed. The confectionery products were evaluated: Kremeš and Venčekcake. For microbiological tests 20 samples of confectionery products were used. The numbers of total count of bacteria ranged from 3.29 log CFU.g-1, the number of mesophilic aerobes bacteria ranged from 1.86 to 2.85 log CFU.g-1, coliforms bacteria in confectionery products ranged from 0to 2.06CFU.g-1and the number of microscopic fungi ranged from 1.13 to 1.96CFU.g-1. The samples of cake prom private production showed better microbiological quality as samples from market production. All investigated samples of confectionary products were inaccordance with the Codex Alimentarius of the Slovak Republic.

International training workshop on quality control and management of food irradiation

International Nuclear Information System (INIS)

2004-01-01

The International Training Workshop on Quality Control and Management of Food Indantrione was hold from 28-30, August, 2004 in Beijing, China and organized by Chinese Society of Nuclear Agriculture and China Isotope and Radiation Association. 10 Articles were collected in this symposium including training lectures. The contents included: international developments in food irradiation, Quality control and magement of food irradiation, industrializing development of irradiated food in China, Food irradiator and its quality management, research in setting standard for enterprise about irradiated products and etc.

[On-site quality control of acupuncture randomized controlled trial: design of content and checklist of quality control based on PICOST].

Science.gov (United States)

Li, Hong-Jiao; He, Li-Yun; Liu, Zhi-Shun; Sun, Ya-Nan; Yan, Shi-Yan; Liu, Jia; Zhao, Ye; Liu, Bao-Yan

2014-02-01

To effectively guarantee quality of randomized controlld trial (RCT) of acupuncture and develop reasonable content and checklist of on-site quality control, influencing factors on quality of acupuncture RCT are analyzed and scientificity of quality control content and feasibility of on-site manipulation are put into overall consideration. Based on content and checklist of on-site quality control in National 11th Five-Year Plan Project Optimization of Comprehensive Treatment Plan for TCM in Prevention and Treatment of Serious Disease and Clinical Assessment on Generic Technology and Quality Control Research, it is proposed that on-site quality control of acupuncture RCT should be conducted with PICOST (patient, intervention, comparison, out come, site and time) as core, especially on quality control of interveners' skills and outcome assessment of blinding, and checklist of on-site quality control is developed to provide references for undertaking groups of the project.

The perception of quality mapping product and service quality to consumer perceptions

CERN Document Server

Kenyon, George N

2015-01-01

Exploring the concept of quality management from a new point of view, this book presents a holistic model of how consumers judge the quality of products. It links consumer perceptions of quality to the design and delivery of the final product, and presents models and methods for improving the quality of these products and services. It offers readers an improved understanding of how and why the design process must consider how the consumer will perceive a product or service. In order to facilitate the presentation and understanding of these concepts, illustrations and case examples are also provided throughout the book.   This book provides an invaluable resource for managers, designers, manufacturers, professional practitioners and academics interested in quality management. It also offers a useful supplementary text for marketing and quality management courses.

7 CFR 58.142 - Product quality and stability.

Science.gov (United States)

2010-01-01

... production of the highest quality of finished product and improve product stability. Milk should not be more... 7 Agriculture 3 2010-01-01 2010-01-01 false Product quality and stability. 58.142 Section 58.142... Procedures § 58.142 Product quality and stability. The receiving, holding and processing of milk and cream...

Design of a Control System for Quality Maintenance on Cutting Edges of Files Production

Directory of Open Access Journals (Sweden)

E. Seabra

2000-01-01

Full Text Available The file cutting edges are the most important parameter that influence the performance of the filing operation. The practice shows that the most efficient way of generating these cutting edges is by penetration, by blow, of a cutting tool, which creates a plastic deformation on the file body. The penetration depth is probably the most important factor of the final quality of a file. In the existing machines of files manufacturing, this depth is manually adjusted by the operator, using specific mechanism. This means that files are manufactured on an empirical basis, relying on subjective factors, that do not allow to keep constant quality level of the production. In a research work, being developed in the University of Minho, it is intended to eliminate the subjectivity factors by the means of the evolution of the present “all-mechanical” system to a “mechatronic” one. In this paper, which is related with that research work, it presented a study of a round files production machine, regarding the identification, as well as the categorisation, of the operating parameters that affect the cutting edges production. They are, as well, defined and quantified those factors that influence the final quality of a round file.

Quality assurance: image production and film quality

International Nuclear Information System (INIS)

Abd Aziz Mhd Ramli

2004-01-01

The contents of this chapter are follows - Factors Affecting Image Quality and Patient Dose: Quality Control in Diagnostic Radiology, Mechanical Safety, Electrical Safety, Radiation Protection, Performance and Safety Standard, Calibration of QC Test Tools

A Quadrupole Dalton-based multi-attribute method for product characterization, process development, and quality control of therapeutic proteins.

Science.gov (United States)

Xu, Weichen; Jimenez, Rod Brian; Mowery, Rachel; Luo, Haibin; Cao, Mingyan; Agarwal, Nitin; Ramos, Irina; Wang, Xiangyang; Wang, Jihong

2017-10-01

During manufacturing and storage process, therapeutic proteins are subject to various post-translational modifications (PTMs), such as isomerization, deamidation, oxidation, disulfide bond modifications and glycosylation. Certain PTMs may affect bioactivity, stability or pharmacokinetics and pharmacodynamics profile and are therefore classified as potential critical quality attributes (pCQAs). Identifying, monitoring and controlling these PTMs are usually key elements of the Quality by Design (QbD) approach. Traditionally, multiple analytical methods are utilized for these purposes, which is time consuming and costly. In recent years, multi-attribute monitoring methods have been developed in the biopharmaceutical industry. However, these methods combine high-end mass spectrometry with complicated data analysis software, which could pose difficulty when implementing in a quality control (QC) environment. Here we report a multi-attribute method (MAM) using a Quadrupole Dalton (QDa) mass detector to selectively monitor and quantitate PTMs in a therapeutic monoclonal antibody. The result output from the QDa-based MAM is straightforward and automatic. Evaluation results indicate this method provides comparable results to the traditional assays. To ensure future application in the QC environment, this method was qualified according to the International Conference on Harmonization (ICH) guideline and applied in the characterization of drug substance and stability samples. The QDa-based MAM is shown to be an extremely useful tool for product and process characterization studies that facilitates facile understanding of process impact on multiple quality attributes, while being QC friendly and cost-effective.

How companies embed non-quantifiable product qualities through their product development process

OpenAIRE

Guldbrandsen, Marianne Norden

2006-01-01

Many consumer products have reached a high level of technical product quality. Rapid adoption of new technologies and access to a global market means that markets are getting saturated. This means that technical differentiation is often not enough to sell a product and products compete more and more on intangible product qualities - these are meant to delight, bring pleasure, be easy to use and to create an experience. These qualities are often difficult to measure in the pr...

Method of controlling the water quality in nuclear reactors

International Nuclear Information System (INIS)

Ibe, Hidefumi.

1985-01-01

Purpose: To obtain a simple and reliable water quality calculation system and water quality control method based thereon for the entire primary coolant circuits in BWR type reactors. Method: In a method of controlling the water quality of the reactor water by injecting hydrogen into the primary coolant circuits of a nuclear reactor, by utilizing a first linear relationship established between the concentration of oxygen and hydrogen in the main steam system and the concentration of radiolysis products in the reactor core and separators and mixing plenum portions, each of the above-mentioned concentrations is calculated from the concentrations for hydrogen or oxygen. Further, by utilizing the first linear relationship established between the concentrations for the oxygen and hydrogen in the recycling system and the concentration of the radiolysis products in the system from the downcomer to the lower plenum portion, the above-mentioned concentration is calculated from the concentration for oxygen and hydrogen. Then, the hydrogen injection rate into the primary coolant system is determined such that the calculated value takes an aimed value. (Ikeda, J.)

Grassland-based products: quality and authentication

NARCIS (Netherlands)

Coppa, M.; Cabiddu, A.; Elsässer, M.; Hulin, S.; Lind, V.; Martin, B.; Mosquera-Losada, M.R.; Peeters, A.; Prache, S.; Pol, van den A.; Peratoner, G.

2017-01-01

There is increased consumer demand for food products with a perceived positive image. Product quality can be assessed in terms of food safety, nutritional composition, technological and sensory characteristics and ethics. In order to summarise the current knowledge linking quality traits and

Soil quality: key for sustainable production

Directory of Open Access Journals (Sweden)

Stefano Mocali

2011-02-01

Full Text Available In the last few years several definitions of “soil quality” have been advanced, but among them the most appreciated is “the ability of soils to interact with the ecosystem in order to maintain the biological productivity, the environmental quality and to promote animal and vegetal health” as defined by Doran and Parkin in 1994. Many researchers place more emphasis on its conceptual meaning for land planning and farm management, while others consider that definition to be worth nothing in order to understand soil properties and the concept of soil quality looks like the concept of “to be suitable for”. For this reason a definition of “soil use” is needed. The food quality is characterized by several properties: the healthiness and the nutritional value, the amount of the production, the typicalness and organoleptic properties, etc.. A lot of these properties depend on environmental quality and, in particular, on soil quality. In fact soil represents the natural substrate for growth and productivity of most of the plants that live on the Hearth because they get all the essential nutritional elements from it for their own development; consequently each nutritional element present into the soil as bioavailable form for the plants is potentially destined to entry in the animal (and human food chain. In the quality process of food productive process it will be important to assure the best soil quality as possible, without any unwanted element (which will not be discussed in this note and with the right amount of fertility elements in order to guarantee the best production. In this paper the relationships between soil quality, soil biodiversity and crop sustainability will be discussed. Finally the concept of soil “biota” as nodal point for the environment regulation and the application of the indicators for soil quality will be discussed.

Soil quality: key for sustainable production

Directory of Open Access Journals (Sweden)

Anna Benedetti

2009-04-01

Full Text Available In the last few years several definitions of “soil quality” have been advanced, but among them the most appreciated is “the ability of soils to interact with the ecosystem in order to maintain the biological productivity, the environmental quality and to promote animal and vegetal health” as defined by Doran and Parkin in 1994. Many researchers place more emphasis on its conceptual meaning for land planning and farm management, while others consider that definition to be worth nothing in order to understand soil properties and the concept of soil quality looks like the concept of “to be suitable for”. For this reason a definition of “soil use” is needed. The food quality is characterized by several properties: the healthiness and the nutritional value, the amount of the production, the typicalness and organoleptic properties, etc.. A lot of these properties depend on environmental quality and, in particular, on soil quality. In fact soil represents the natural substrate for growth and productivity of most of the plants that live on the Hearth because they get all the essential nutritional elements from it for their own development; consequently each nutritional element present into the soil as bioavailable form for the plants is potentially destined to entry in the animal (and human food chain. In the quality process of food productive process it will be important to assure the best soil quality as possible, without any unwanted element (which will not be discussed in this note and with the right amount of fertility elements in order to guarantee the best production. In this paper the relationships between soil quality, soil biodiversity and crop sustainability will be discussed. Finally the concept of soil “biota” as nodal point for the environment regulation and the application of the indicators for soil quality will be discussed.

Layoffs and tradeoffs: production, quality, and safety demands under the threat of job loss.

Science.gov (United States)

Probst, Tahira M

2002-07-01

Employees often face a conflict between production targets, quality assurance, and adherence to safety policies. In a time when layoffs are on the rise, it is important to understand the effects of employee job insecurity on these potentially competing demands. A laboratory experiment manipulated the threat of layoffs in a simulated organization and assessed its effect on employee productivity, product quality, and adherence to safety policies. Results suggest that student participants faced with the threat of layoffs were more productive, yet violated more safety rules and produced lower quality outputs, than participants in the control condition. Implications for organizations contemplating layoffs and directions for future research are discussed.

QUALITY IMPROVEMENT USING STATISTICAL PROCESS CONTROL TOOLS IN GLASS BOTTLES MANUFACTURING COMPANY

Directory of Open Access Journals (Sweden)

Yonatan Mengesha Awaj

2013-03-01

Full Text Available In order to survive in a competitive market, improving quality and productivity of product or process is a must for any company. This study is about to apply the statistical process control (SPC tools in the production processing line and on final product in order to reduce defects by identifying where the highest waste is occur at and to give suggestion for improvement. The approach used in this study is direct observation, thorough examination of production process lines, brain storming session, fishbone diagram, and information has been collected from potential customers and company's workers through interview and questionnaire, Pareto chart/analysis and control chart (p-chart was constructed. It has been found that the company has many problems; specifically there is high rejection or waste in the production processing line. The highest waste occurs in melting process line which causes loss due to trickle and in the forming process line which causes loss due to defective product rejection. The vital few problems were identified, it was found that the blisters, double seam, stone, pressure failure and overweight are the vital few problems. The principal aim of the study is to create awareness to quality team how to use SPC tools in the problem analysis, especially to train quality team on how to held an effective brainstorming session, and exploit these data in cause-and-effect diagram construction, Pareto analysis and control chart construction. The major causes of non-conformities and root causes of the quality problems were specified, and possible remedies were proposed. Although the company has many constraints to implement all suggestion for improvement within short period of time, the company recognized that the suggestion will provide significant productivity improvement in the long run.

Quality of handwriting: Intervention based on the variation of finger force production

Directory of Open Access Journals (Sweden)

Adriano Percival Calvo

2014-09-01

Full Text Available Difficulties in the production of proficient handwriting can be detected early in childhood. From the control point of view, non-proficient handwriting can be explained by the difficulty in adequately activating motor synergies that give support to this motor skill. Therefore, imposing different demand on the control to the motor synergies of the fingers can generate improvement in the quality of handwriting. The goal of the present study was to verify the effects of an intervention program for children with handwriting difficulties, composed of manipulative and pre-calligraphic activities that stimulate finger motor synergies through different force production demands. Thirty-four children between 7 and 12 years of age participated in the present study. Handwriting quality was evaluated through the Minnesota Handwriting Assessment. Only the experimental group (n=18 was submitted to the intervention program developed throughout 27 sessions of 30 minutes each. The results indicate that the intervention program based on the variability of force production had a positive effect on the quality of handwriting,mainly in terms of the size of letters.

Quality Control System using Simple Implementation of Seven Tools for Batik Textile Manufacturing

Science.gov (United States)

Ragil Suryoputro, Muhammad; Sugarindra, Muchamad; Erfaisalsyah, Hendy

2017-06-01

In order to produce better products and mitigate defect in products, every company must implement a quality control system. Company will find means to implement a quality control system that is capable and reliable. One of the methods is using the simple implementation of the seven tools in quality control defects. The case studied in this research was the level of disability xyz grey fabric on a shuttle loom 2 on the Batik manufacturing company. The seven tools that include: flowchart, check sheet, histogram, scatter diagram combined with control charts, Pareto diagrams and fishbone diagrams (causal diagram). Check sheet results obtained types of defects in the grey fabric was woven xyz is warp, double warp, the warp break, double warp, empty warp, warp tenuous, ugly edges, thick warp, and rust. Based on the analysis of control chart indicates that the process is out of control. This can be seen in the graph control where there is still a lot of outlier data. Based on a scatter diagram shows a positive correlation between the percentage of disability and the number of production. Based on Pareto diagram, repair needs priority is for the dominant type of defect is warp (44%) and based on double warp value histogram is also the highest with a value of 23635.11 m. In addition, based on the analysis of the factors causing defect by fishbone diagram double warp or other types of defects originating from the materials, methods, machines, measurements, man and environment. Thus the company can take to minimize the prevention and repair of defects and improve product quality.

Fabrication, Quality Assurance, and Quality Control for PROSPECT Detector Component Production

Science.gov (United States)

Gustafson, Ian; Prospect (The Precision Reactor Oscillation; Spectrum Experiment) Collaboration

2017-09-01

The Precision Reactor Oscillation and Spectrum Experiment (PROSPECT) is an electron antineutrino (νe) detector intended to make a precision measurement of the 235U neutrino spectrum and to search for the possible existence of sterile neutrinos with a mass splitting of Δm2 on the order of 1 eV2 . As a short baseline detector, PROSPECT will be located less than 10 meters from the High Flux Isotope Reactor at Oak Ridge National Laboratory. As PROSPECT intends to search for baseline-dependent oscillations, physical segmentation is needed to better measure the interaction position. PROSPECT will therefore be a segmented detector in two dimensions, thereby improving position measurements. PROSPECT will be segmented into 154 (11×14) 1.2-meter long rectangular tubes, using optical separators. Each separator will consist of a carbon fiber core, laminated with optical reflector (to increase light collection) and Teflon (to ensure compatibility with the scintillator). These optical separators will be held in place via strings of 3D printed PLA rods called `pinwheels.' This poster discusses the fabrication and quality assurance (QA) procedures used in the production of both the PROSPECT optical separators and pinwheels. For the PROSPECT collaboration.

Theoretical bases of management product quality as one of the main direction of maintenance of industrial competitiveness

OpenAIRE

Dykan, O.

2015-01-01

In the article the author considered the essence of the concept of "product stewardship" as one of the main areas to ensure industrial competitiveness. Given the current negative trends in the development of industry in Ukraine and low competitiveness of domestic products, the necessity of rethinking the dominant principles, stages and functions of quality control. The main problems of implementation of the process of product quality control to domestic industrial enterprises. As a conclusion...

The legal framework governing the quality of (traditional) herbal medicinal products in the European Union.

Science.gov (United States)

Kroes, Burt H

2014-12-02

to herbal products based on clinical evidence and traditional herbal medicinal products. The basic principle is that the quality of herbal medicinal products is intrinsically associated with the quality standard of the herbal substances and/or herbal preparations. Furthermore, the herbal substance or herbal preparation in its entirety is regarded as the active substance. Consequently, a mere determination of the content of marker(s) or constituents with known therapeutic activity is not sufficient for the quality control of herbal medicinal products. Specific quality requirements include thorough product characterisation, adherence to the Good Agricultural and Collection Practices, good manufacturing practices and validated manufacturing process, e.g., raw material testing, in-process testing, fingerprint characterisation etc. Quality control of herbal medicinal products is primarily intended to define the quality of the herbal substance/preparation and herbal medicinal product rather than to establish full characterisation. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Planning product quality: An example - ornamental plants

Directory of Open Access Journals (Sweden)

Kovačević Miodrag

2003-01-01

Full Text Available The industry of ornamental plants is a subject of quality planning. The quality plan is a document setting out the specific quality practices in ornamental plants production. That plan introduce organizational structure procedures, processes and resources needed to implement quality in life cycle of product chain. For engineers it represents a new tool.

Assessing product image quality for online shopping

Science.gov (United States)

Goswami, Anjan; Chung, Sung H.; Chittar, Naren; Islam, Atiq

2012-01-01

Assessing product-image quality is important in the context of online shopping. A high quality image that conveys more information about a product can boost the buyer's confidence and can get more attention. However, the notion of image quality for product-images is not the same as that in other domains. The perception of quality of product-images depends not only on various photographic quality features but also on various high level features such as clarity of the foreground or goodness of the background etc. In this paper, we define a notion of product-image quality based on various such features. We conduct a crowd-sourced experiment to collect user judgments on thousands of eBay's images. We formulate a multi-class classification problem for modeling image quality by classifying images into good, fair and poor quality based on the guided perceptual notions from the judges. We also conduct experiments with regression using average crowd-sourced human judgments as target. We compute a pseudo-regression score with expected average of predicted classes and also compute a score from the regression technique. We design many experiments with various sampling and voting schemes with crowd-sourced data and construct various experimental image quality models. Most of our models have reasonable accuracies (greater or equal to 70%) on test data set. We observe that our computed image quality score has a high (0.66) rank correlation with average votes from the crowd sourced human judgments.

Quality management

International Nuclear Information System (INIS)

1989-01-01

The 1989 Quality Management Conference focusses on process control and the thus achievable product quality. It is shown that the buyers' increasing demands on product quality require appropriate response in terms of enhanced efforts and methods for quality assurance in the production process. The connection between quality targets and the expenditure required is shown, as well as a comparative validation of efficiency of quality assurance methods. The firms selected for representation at this conference cover a wide range of products so that practically the entire scope of process control problems in the various industrial branches is discussed in the conference contributions. The last conference session is concerned with the strategies and technical developments for enhanced combination of quality assurance and control and production processes. (orig./HP) [de

The production of the heavy pig for high quality processed products

Directory of Open Access Journals (Sweden)

Paolo Bosi

2010-01-01

Full Text Available The review discusses the topics presented below, with experimental data and more evidence for some aspects which areproblematic for the pig producer. To obtain high quality processed pig products, heavy pig production in Italy is subjectedto rules fixed by several Consortia, on the basis of the experience of producers and the results from scientific research.Slaughter animals of at least 9 months of age and 160 kg live weight are required to provide heavy cuts with excellentmeat. Breeds are limited to Italian Large White and Landrace, selected for specific parameters such as loss at 1st saltingof the ham, and their crosses. Crosses with Duroc and hybrids can be used if obtained from selection and crossingschemes that fit the objectives of Italian selection. Backfat thickness must be “sufficient” to obtain retailed fresh hamswith fat cover ranging from 20 to 30 mm, depending on ham weight, and the content of linoleic acid in ham fat covercannot exceed 15%. Fat quantity and quality in feeds should be carefully controlled to satisfy the quality of fat in theham. The feeding level is also relevant, due to the imposed minimum age at slaughter. Feed restriction is a necessarypractice to respect the rules for ham production. For castrate males of medium genetic value, the restriction shouldreduce fat deposition, but the diet composition can be adapted to maintain the maximum growth of protein. For strainswith high lean deposition potential and particularly for gilts, protein deposition should also be limited to maintain a sufficientfat cover of ham.

Quality control in nuclear medicine

International Nuclear Information System (INIS)

Leme, P.R.

1983-01-01

The following topics are discussed: objectives of the quality control in nuclear medicine; the necessity of the quality control in nuclear medicine; guidelines and recommendations. An appendix is given concerning the guidelines for the quality control and instrumentation in nuclear medicine. (M.A.) [pt

The Validation of the GEWEX SRB Surface Shortwave Flux Data Products Using BSRN Measurements: A Systematic Quality Control, Production and Application Approach

Science.gov (United States)

Zhang, Taiping; Stackhouse, Paul W., Jr.; Gupta, Shashi K.; Cox, Stephen J.; Mikovitz, J. Colleen; Hinkelman, Laura M.

2013-01-01

The NASA/GEWEX Surface Radiation Budget (SRB) project has produced a 24.5-year continuous record of global shortwave and longwave radiation fluxes at TOA and the Earth's surface from satellite measurements. The time span of the data is from July 1983 to December 2007, and the spatial resolution is 11 latitude11 longitude. The inputs of the latest version (Release 3.0) include the GEOS Version 4.0.3 meteorological information and cloud properties derived from ISCCP DX data. The SRB products are available on 3-hourly, 3-hourly-monthly, daily and monthly time scales. To assess the quality of the product, we extensively validated the SRB data against 5969 site-months of groundbased measurements from 52 Baseline Surface Radiation Network (BSRN) stations. This paper describes first the characteristics of the BSRN data and the GEWEX SRB data, the methodology for quality control and processing of the shortwave BSRN data, and then the systematic SRB-BSRN comparisons. It is found that, except for occasional extreme outliers as seen in scatter plots, the satellite-based surface radiation data generally agree very well with BSRN measurements. Specifically, the bias/RMS for the daily and monthly mean shortwave fluxes are, respectively, -3.6/35.5 and -5.2/23.3W1 m2 under all-sky conditions.

Good air quality in offices improves productivity

DEFF Research Database (Denmark)

Fanger, Povl Ole

2000-01-01

Three recent independent studies have documented that the quality of indoor air has a significant and positive influence or? the productivity of office workers. A combined analysis of the results of the three studies shows a significant relationship between productivity and perceived indoor air...... quality. The impact on productivity justifies a much higher indoor air quality than the minimum levels prescribed in present standards and guidelines. One way of providing air of high quality for people to breathe, without involving excessive ventilation rates and energy use, is to provide "personalized...

Good air quality in offices improves productivity

DEFF Research Database (Denmark)

Fanger, Povl Ole

2000-01-01

Three recent independent studies have documented that the quality of indoor air has a significant and positive influence on the productivity of office workers. A combined analysis of the results of the three studies shows a significant relationship between productivity and perceived indoor air...... quality. The impact on productivity justifies a much higher indoor air quality than the minimum levels prescribed in present standards and guidelines. One way of providing air of high quality for people to breathe, without involving excessive ventilation rates and energy use, is to provide "personalized...

Demerit control chart as a decision support tool in quality control of ductile cast-iron casting process

Directory of Open Access Journals (Sweden)

Sika Robert

2017-01-01

Full Text Available In many industrial areas the product quality can be unequivocally assigned to classes such as: “good”, “bad” or “to repair”. In case of casting processes, the product is approved to sales considering customer’s requirements. Except for common characteristics, such as structure, compactness and mechanical properties, physical state of the product is also important. This state is assessed by checking occurrence of specific kind of defects. They are often conditionally accepted by a customer if they do not have any influence on functionality of the product (e.g. negative adhesive and cohesive phenomena, fatigue strength, thermal shocks. Authors’ experience shows that current registering of the most frequently occurring defects and comparing them to customers’ requirements can be very useful and help a quality engineer to control the casting process. They suggest using the Demerit Control Chart (DCC, according to authors’ own methodology, in aspect of information about the castings accepted conditionally by a customer (DCC-recognition. DCC-recognition can be used to assess this quality by monitoring the value of just one aggregated measure for all kinds of defects instead of using a single attribute control chart for each of them. The test version of this tool considering severity of defects proved to be useful in one of the European foundries.

AN ANALYSIS OF THE CAUSES OF PRODUCT DEFECTS USING QUALITY MANAGEMENT TOOLS

Directory of Open Access Journals (Sweden)

Katarzyna MIDOR

2014-10-01

Full Text Available To stay or strengthen its position on the market, a modern business needs to follow the principles of quality control in its actions. Especially important is the Zero Defects concept developed by Philip Crosby, which means flawless production. The concept consists in preventing the occurrence of defects and flaws in all production stages. To achieve that, we must, among other things, make use of quality management tools. This article presents an analysis of the reasons for the return of damaged or faulty goods in the automotive industry by means of quality management tools such as the Ishikawa diagram and Pareto analysis, which allow us to identify the causes of product defectiveness. Based on the results, preventive measures have been proposed. The actions presented in this article and the results of the analysis prove the effectiveness of the aforementioned quality management tools.

Problems concerning product quality enhancement

Directory of Open Access Journals (Sweden)

Marek Krynke

2016-03-01

Full Text Available In the article analysis of the discrepancies in the production process for selected products in a company producing candles was carried out. Using the Pareto-Lorenzdiagram and the FMEA method the most essential areas having influence on the production of candles were shown. Apart from factors connected with the manufacturing side of the process, factors of the labour organization and requirements concerning the quality of material were also noted. An appropriate quality of equipment constitutes one of the essential conditions of production process functioning and this directly influences manufacturing possibilities of the enterprise. A synthesis of immaterial factors that influence the production of the enterprise, taking into consideration conditions of functioning the production system, was also carried out. The set of factors selected for description was the fourteenth Toyota management principle. Respondents were asked to provide answers which could bring the best improvements.

[Application of THz technology to nondestructive detection of agricultural product quality].

Science.gov (United States)

Jiang, Yu-ying; Ge, Hong-yi; Lian, Fei-yu; Zhang, Yuan; Xia, Shan-hong

2014-08-01

With recent development of THz sources and detector, applications of THz radiation to nondestructive testing and quality control have expanded in many fields, such as agriculture, safety inspection and quality control, medicine, biochemistry, communication etc. Compared with other detection technique, being a new kind of technique, THz radiation has low energy, good perspectivity, and high signal-to-noise ratio, and thus can obtain physical, chemical and biological information. This paper first introduces the basic concept of THz radiation and the major properties, then gives an extensive review of recent research progress in detection of the quality of agricultural products via THz technique, analyzes the existing shortcomings of THz detection and discusses the outlook of potential application, finally proposes the new application of THz technique to detection of quality of stored grain.

Quality risk in outsourcing: noncontractible product quality and private quality cost information

OpenAIRE

Kaya, Murat; Özer, Özalp; Ozer, Ozalp

2009-01-01

This article addresses the concept of quality risk in outsourcing. Recent trends in outsourcing extend a contract manufacturer's (CM's) responsibility to several functional areas, such as research and development and design in addition to manufacturing. This trend enables an original equipment manufacturer (OEM) to focus on sales and pricing of its product. However, increasing CM responsibilities also suggest that the OEM's product quality is mainly determined by its CM. We identify two facto...

[The technological innovation strategy for quality control of Chinese medicine based on Big Data].

Science.gov (United States)

Li, Zhen-hao; Qian, Zhong-zhi; Cheng, Yi-yu

2015-09-01

The evolution of the quality control concepts of medical products within the global context and the development of the quality control technology of Chinese medicine are briefly described. Aimed at the bottlenecks in the regulation and quality control of Chinese medicine, using Big Data technology to address the significant challenges in Chinese medicine industry is proposed. For quality standard refinements and internationalization of Chinese medicine, a technological innovation strategy encompassing its methodology, and the R&D direction of the subsequent core technology are also presented.

40 CFR 75.21 - Quality assurance and quality control requirements.

Science.gov (United States)

2010-07-01

... quality assurance audit or any other audit, the system is out-of-control. The owner or operator shall... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Quality assurance and quality control... assurance and quality control requirements. (a) Continuous emission monitoring systems. The owner or...

Integrated evolutionary computation neural network quality controller for automated systems

Energy Technology Data Exchange (ETDEWEB)

Patro, S.; Kolarik, W.J. [Texas Tech Univ., Lubbock, TX (United States). Dept. of Industrial Engineering

1999-06-01

With increasing competition in the global market, more and more stringent quality standards and specifications are being demands at lower costs. Manufacturing applications of computing power are becoming more common. The application of neural networks to identification and control of dynamic processes has been discussed. The limitations of using neural networks for control purposes has been pointed out and a different technique, evolutionary computation, has been discussed. The results of identifying and controlling an unstable, dynamic process using evolutionary computation methods has been presented. A framework for an integrated system, using both neural networks and evolutionary computation, has been proposed to identify the process and then control the product quality, in a dynamic, multivariable system, in real-time.

Beneficial and Harmful Agile Practices for Product Quality

OpenAIRE

Theobald, Sven; Diebold, Philipp

2017-01-01

There is the widespread belief that Agile neglects the product quality. This lack of understanding how Agile processes assure the quality of the product prevents especially companies from regulated domains from an adoption of Agile. This work aims to identify which Agile Practices contribute towards product quality. Hence, data from a survey study is analyzed to identify Ag-ile Practices which are beneficial or harmful for the quality of the product. From 49 practices that were used in the su...

Commercial jet fuel quality control

Energy Technology Data Exchange (ETDEWEB)

Strauss, K.H.

1995-05-01

The paper discusses the purpose of jet fuel quality control between the refinery and the aircraft. It describes fixed equipment, including various types of filters, and the usefulness and limitations of this equipment. Test equipment is reviewed as are various surveillance procedures. These include the Air Transport Association specification ATA 103, the FAA Advisory Circular 150/5230-4, the International Air Transport Association Guidance Material for Fuel Quality Control and Fuelling Service and the Guidelines for Quality Control at Jointly Operated Fuel Systems. Some past and current quality control problems are briefly mentioned.

SPECT quality control tests

International Nuclear Information System (INIS)

Robilotta, C.C.; Rebelo, M.F.S.; Oliveira, M.A.; Abe, R.

1987-01-01

Quality control tests of tomographic system composed by a rotatory chamber (CGR Gammatomome T-9000) and a microcomputer are presented. Traditional quality control tests for scintilation chambers and specific tests for tomographic systems are reported. (M.A.C.) [pt

The use of HPLC in the control of Neem commercial products quality: reproduction of the insecticide action

International Nuclear Information System (INIS)

Forim, Moacir Rossi; Matos, Andreia Pereira; Silva, Maria Fatima das Gracas Fernandes da; Cass, Quezia Bezerra; Vieira, Paulo Cezar; Fernandes, Joao Batista

2010-01-01

The Neem tree, Azadirachta indica, provides many useful compounds that are used as pesticides. However, the efficiency in field of products like neem oil can be committed because they have not been observed reproductive content of secondary metabolic like azadirachtin. Based on reverse-phase high-performance liquid chromatography (HPLC) a new method was developed to permit the rapid quantitative analysis of azadirachtin from seeds, extracts and oil of Neem. In the present study it was evaluated the azadirachtin quantitative variation among various Neem's extracts and seeds showing the importance of quality control for reproduction of the insecticide efficiency, using S. frugiperda as target insect. (author)

MapReduce Based Parallel Bayesian Network for Manufacturing Quality Control

Science.gov (United States)

Zheng, Mao-Kuan; Ming, Xin-Guo; Zhang, Xian-Yu; Li, Guo-Ming

2017-09-01

Increasing complexity of industrial products and manufacturing processes have challenged conventional statistics based quality management approaches in the circumstances of dynamic production. A Bayesian network and big data analytics integrated approach for manufacturing process quality analysis and control is proposed. Based on Hadoop distributed architecture and MapReduce parallel computing model, big volume and variety quality related data generated during the manufacturing process could be dealt with. Artificial intelligent algorithms, including Bayesian network learning, classification and reasoning, are embedded into the Reduce process. Relying on the ability of the Bayesian network in dealing with dynamic and uncertain problem and the parallel computing power of MapReduce, Bayesian network of impact factors on quality are built based on prior probability distribution and modified with posterior probability distribution. A case study on hull segment manufacturing precision management for ship and offshore platform building shows that computing speed accelerates almost directly proportionally to the increase of computing nodes. It is also proved that the proposed model is feasible for locating and reasoning of root causes, forecasting of manufacturing outcome, and intelligent decision for precision problem solving. The integration of bigdata analytics and BN method offers a whole new perspective in manufacturing quality control.

Quality control and assurance of Tc-99m generators and kits applied in SAEC laboratories

International Nuclear Information System (INIS)

Yassine, T.

1998-01-01

A brief description of quality assurance and quality control system applied in SAEC laboratories for production of 99m Tc-radiopharmaceuticals, is provided. The system includes documentation, procedures, releasing of the products and responsibilities. The system described here undergoes a continues development. (author)

Sterile kits for the preparation of radiopharmaceuticals: some basic quality control considerations

International Nuclear Information System (INIS)

Briner, W.H.

1975-01-01

Quality control concepts involved in the formulation of radiopharmaceutical kits, as well as all other radiopharmaceuticals, are meant to protect both the patients who receive these products and the practitioners of nuclear medicine who use these products in their practice. These concepts include the adequacy of site and facilities in which these products are formulated, the level of training and experience of personnel responsible for the formulation of the products, quality assurance procedures employed to monitor the acceptability of products, and, finally, a professional dedication to excellence in all these matters. The absence of any of these in a nuclear medicine or radiopharmaceutical program will result in almost certain disaster

[Internal quality control of the blood products in the Lomé National Blood Transfusion Centre].

Science.gov (United States)

Fétéké, L; Mawussi, K; Lakté, P; Kuéviakoe, I M; Haudrechy, D; Ségbéna, A Y

2008-07-01

Evaluate the conformity of blood red cells units prepared in the Lomé CNTS with European norms concerning volume, haemoglobin content and haematocrite. Measure the conservation of the haemostatic properties and the rate of haemostasis factors V and VIII in the fresh frozen plasma. Measure the rate of residual cells in the plasma. In the year 2006, from March 1st to April 15th, we analysed the quality of 135 units of whole blood, red blood cells (RBC) and plasma from blood donors in the Lomé National Blood Transfusion Centre. The quality control had concerned: the volume of whole blood units; the volume, the haemoglobin content and the haematocrite of red blood cells units; the volume, the prothrombin rate, the cephalin with activator time (TCA), the rate of haemostasis factors V and VIII and the number of residual cells (red cells, leucocytes and platelets) in the plasma. Among the 135 units of whole blood which were controlled, 50.57% were in conformity with the norms concerning the volume. The red blood cells units were in conformity with norms concerning their volume, their haemoglobin content and their haematocrite respectively in 21.48%, 80.75% and 20% of the cases. The volume of 75.56% of the plasma units controlled were conform with the norm. All of the plasma units were conform with the norm concerning the number of residual platelets while the number of residual red blood cells and leucocytes were conform respectively in 80.74% and 60%. The percentage of conformity concerning the prothrombin rate, the TCA, the coagulation factor V and the factor VIII were respectively 66.67; 97.78; 48.89 and 47.4 before freezing, and 54.81; 88.14; 64.44; 84.44 a month after freezing. To improve the quality of the new blood products of the Lomé CNTS, some correctives actions must be applied concerning the adequate volume of blood which must be collected from the donors, the position of the blood bags in during the centrifugation and the volume of plasma which must be

HACCP system for quality control of food irradiation

Energy Technology Data Exchange (ETDEWEB)

Yiming, Ha [The Institute of Application of Atomic Energy, CAAS, Beijing (China)

2004-02-01

This paper introduces the Hazard Analysis and Critical Control Point System (HACCP) and analyses all hazard factors which would possibly affect the product quality in processing of irradiation dehydrated vegetables. It suggests that the irradiation food factories in China should set up HACCP as soon as possible and discusses the ways to set up HACCP.

HACCP system for quality control of food irradiation

International Nuclear Information System (INIS)

Ha Yiming

2004-01-01

This paper introduces the Hazard Analysis and Critical Control Point System (HACCP) and analyses all hazard factors which would possibly affect the product quality in processing of irradiation dehydrated vegetables. It suggests that the irradiation food factories in China should set up HACCP as soon as possible and discusses the ways to set up HACCP

Microbiological quality and safety assessment of lettuce production in Brazil.

Science.gov (United States)

Ceuppens, Siele; Hessel, Claudia Titze; de Quadros Rodrigues, Rochele; Bartz, Sabrina; Tondo, Eduardo César; Uyttendaele, Mieke

2014-07-02

The microbiological quality and safety of lettuce during primary production in Brazil were determined by enumeration of hygiene indicators Escherichia coli, coliforms and enterococci and detection of enteric pathogens Salmonella and E. coli O157:H7 in organic fertilizers, soil, irrigation water, lettuce crops, harvest boxes and worker's hands taken from six different lettuce farms throughout the crop growth cycle. Generic E. coli was a suitable indicator for the presence of Salmonella and E. coli O157:H7, while coliforms and enterococci were not. Few pathogens were detected: 5 salmonellae and 2 E. coli O157:H7 from 260 samples, of which only one was lettuce and the others were manure, soil and water. Most (5/7) pathogens were isolated from the same farm and all were from organic production. Statistical analysis revealed the following environmental and agro-technical risk factors for increased microbial load and pathogen prevalence in lettuce production: high temperature, flooding of lettuce fields, application of contaminated organic fertilizer, irrigation with water of inferior quality and large distances between the field and toilets. Control of the composting process of organic fertilizers and the irrigation water quality appear most crucial to improve and/or maintain the microbiological quality and safety during the primary production of lettuce. Copyright © 2014 Elsevier B.V. All rights reserved.

Design and implementation of strategies for the assurance of quality for sterility testing in the Quality Control Section of the Chilean Nuclear Energy Commission

International Nuclear Information System (INIS)

Olave Carreno, Evelyn Karina

2015-01-01

The Department of Production and Service of the Chilean Nuclear Energy Commission (CCHEN), is an organization dedicated to the production and quality control of radioisotopes and radiopharmaceuticals. To be considered pharmaceutical specialties, the department has implemented a quality assurance system to guarantee compliance with the required standards during manufacturing processes, quality control and distribution. Such products are administered, mostly by via parental; that is why it is extremely important that as an injectable solution is sterile non-pyrogenic. Therefore, the Head of Quality Control Section emphasized the importance of validating sterility testing for these products. In the first instance we proceeded to update the related documentation, as this is one of the essential pillars of a good system of quality assurance, then continuing with the verification of compliance with the physical conditions of the place where the infertility tests are performed (classification of areas from a microbiological point of view). During this process, the proper training of personnel involved in performing environmental testing and sterility testing was performed. Finally, we proceeded to validate the sterility test by the method of direct inoculation three radiopharmaceuticals; also implemented sterility testing by membrane filtration method described in the USP. It was possible to validate the methods of direct inoculation and membrane filtration based on the validation protocol guidelines generated and previously approved by the Chief; demonstrating that in both cases the detection of reference strains of inocula is achieved under 100 cfu (Staphylococcus aureus, Bacillus spizizenii, Pseudomonas aeruginosa, Clostridium sporogenes, Candida albicans, Aspergillus brasiliensis), without interference of two of the products tested and interference of a product by direct inoculation method which was resolved. Based on these results, the documented evidence that

Quality control of ATLAS muon chambers

CERN Document Server

Fabich, Adrian

ATLAS is a general-purpose experiment for the future Large Hadron Collider (LHC) at CERN. Its Muon Spectrometer will require ∼ 5500m2 of precision tracking chambers to measure the muon tracks along a spectrometer arm of 5m to 15m length, embedded in a magnetic field of ∼ 0.5T. The precision tracking devices in the Muon System will be high pressure drift tubes (MDTs). Approximately 370,000 MDTs will be assembled into ∼ 1200 drift chambers. The performance of the MDT chambers is very much dependent on the mechanical quality of the chambers. The uniformity and stability of the performance can only be assured providing very high quality control during production. Gas tightness, high-voltage behaviour and dark currents are global parameters which are common to gas detectors. For all chambers, they will be tested immediately after the chamber assembly at every production site. Functional tests, for example radioactive source scans and cosmic-ray runs, will be performed in order to establish detailed performan...

Constitution of a centralised data base for the internal quality control in radiotherapy

International Nuclear Information System (INIS)

Fau, P.; Rodrigues, C.; Ruchaud, R.; Bravetti, J.

2009-01-01

The objective of this project was to implement a centralised data base of internal quality control in radiotherapy according to the criteria of the decree of A.f.s.s.a.p.s. (French agency of sanitary safety of health products on 27 july 2007, about the internal quality control of external radiotherapy facilities. The software on one year meets the objectives: compliance by comparison with A.f.s.s.a.p.s. criteria but particularly optimization of the centralisation and analysis of the internal quality controls. (N.C.)

Experiences in the application of quality control and quality assurance programmes in water reactor fuel fabrication

International Nuclear Information System (INIS)

Balaramamoorthy, K.; Vijayaraghavan, R.; Kulkarni, P.G.; Raghavan, S.V.; Bandyopadhyay, A.K.

1984-01-01

Nuclear fuel for Research Reactors and Pressurised Heavy Water Reactors (PHWRs) is being fabricated in India for a period of over two decades. The fuel is produced to conform to stringent quality control specifications. Generally, the performance of the fuel has been very good in the reactors. This is not only due to the high quality workmanship in the various stages of production but also to the meticulous care exercised in the planning and application of quality control and quality assurance procedures. For the nuclear fuel used in Water Reactors, extensive material specifications have been compiled and they are periodically reviewed and revised. The specifications cover various aspects such as metallurgical and mechanical properties, non-destructive testing, dimensional and visual standard requirements. Similarly, detailed manufacturing engineering instructions (MEIs) and quality control instructions (QCIs) have been drawn. For any deviations from the specified requirements, design concession committee considers all deviations and acceptance or rejection criteria are evolved. In this task, the design concession committee is supported by experimentation in various laboratories of the Department of Atomic Energy. The Quality Assurance procedures have been evolved over a long period of time. They generally conform to the latest code and recommended guides of IAEA regarding Quality Assurance in the manufacture of fuel. (orig.)

21 CFR 111.120 - What quality control operations are required for components, packaging, and labels before use in...

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What quality control operations are required for..., OR HOLDING OPERATIONS FOR DIETARY SUPPLEMENTS Production and Process Control System: Requirements for Quality Control § 111.120 What quality control operations are required for components, packaging, and...

Guidebook on quality control of water reactor fuel

International Nuclear Information System (INIS)

1983-01-01

As a result of the increasing contribution of nuclear power to the world's supply of electrical energy, growing emphasis is being placed on the reliability of nuclear fuel performance. The need to produce a reliable product is based not only on economic reasons but also on safety considerations. Fuel assemblies must withstand the operational requirements placed on them while in the reactor; also, in some cases, they have to be stored for long periods in water-filled basins until they are either reprocessed or ultimately subjected to disposal. One of the keys to consistent and reliable fuel production is an adequate Quality Control (QC) programme, operating under a Quality Assurance (QA) system. In connection with various activities sponsored by the International Atomic Energy Agency it has been suggested for some time that a guidebook should be published, highlighting the role that QC plays in the manufacture of nuclear fuel and stressing the relationship that exists between the QC and QA functions. The aim of this book is to give a summary of the present state of practical experience in the areas of: quality-relevant design requirements; quality control of products and processes. Specific QA requirements are referred to where they are important for an understanding of the co-operation required between the various activities involved in nuclear fuel technology. Examples are also given to illustrate specific needs or specific types of experience in this area. In order to distinguish clearly between the generally required criteria and rules and the details of particular practical experience, the book is divided into two main parts. Part A focuses on the philosophy and principles; Part B supplements Part A with technically detailed descriptions and examples

Quality assurance and quality control of nuclear engineering during construction phase

International Nuclear Information System (INIS)

Zhang Zhihua; Deng Yue; Liu Yaoguang; Xu Xianqi; Zhou Shan; Qian Dazhi; Zhang Yang

2007-01-01

The quality assurance (QA) and quality control (QC) is a very important work in the nuclear engineering. This paper starts with how to establish quality assurance system of nuclear engineering construction phase, then introduces several experiments and techniques such as the implementation of quality assurance program, the quality assurance and quality control of contractors, the quality surveillance and control of supervisory companies, quality assurance audit and surveillance of builders. (authors)

Batch-to-batch quality consistency evaluation of botanical drug products using multivariate statistical analysis of the chromatographic fingerprint.

Science.gov (United States)

Xiong, Haoshu; Yu, Lawrence X; Qu, Haibin

2013-06-01

Botanical drug products have batch-to-batch quality variability due to botanical raw materials and the current manufacturing process. The rational evaluation and control of product quality consistency are essential to ensure the efficacy and safety. Chromatographic fingerprinting is an important and widely used tool to characterize the chemical composition of botanical drug products. Multivariate statistical analysis has showed its efficacy and applicability in the quality evaluation of many kinds of industrial products. In this paper, the combined use of multivariate statistical analysis and chromatographic fingerprinting is presented here to evaluate batch-to-batch quality consistency of botanical drug products. A typical botanical drug product in China, Shenmai injection, was selected as the example to demonstrate the feasibility of this approach. The high-performance liquid chromatographic fingerprint data of historical batches were collected from a traditional Chinese medicine manufacturing factory. Characteristic peaks were weighted by their variability among production batches. A principal component analysis model was established after outliers were modified or removed. Multivariate (Hotelling T(2) and DModX) control charts were finally successfully applied to evaluate the quality consistency. The results suggest useful applications for a combination of multivariate statistical analysis with chromatographic fingerprinting in batch-to-batch quality consistency evaluation for the manufacture of botanical drug products.

Official control of plant protection products in Poland: detection of illegal products.

Science.gov (United States)

Miszczyk, Marek; Płonka, Marlena; Stobiecki, Tomasz; Kronenbach-Dylong, Dorota; Waleczek, Kazimierz; Weber, Roland

2018-04-03

Market presence of illegal and counterfeit pesticides is now a global problem. According to data published in 2012 by the European Crop Protection Association (ECPA), illegal products represent over 10% of the global market of plant protection products. Financial benefits are the main reason for the prevalence of this practice. Counterfeit and illegal pesticides may contain substances that may pose a threat to the environment, crops, animals, and humans, inconsistent with the label and registration dossier. In Poland, action against illegal and counterfeit plant protection products is undertaken by the Main Inspectorate of Plant Health and Seed Inspection (PIORiN), the police, the prosecution, and the pesticide producers. Results of chemical analyses carried out by the Institute of Plant Protection - National Research Institute Sośnicowice Branch, Pesticide Quality Testing Laboratory (PQTL IPP-NRI Sosnicowice Branch) indicate that a majority of illegal pesticides in Poland are detected in the group of herbicides. Products from parallel trade tend to have the most irregularities. This article describes the official quality control system of plant protection products in Poland and presents the analytical methods for testing pesticides suspected of adulteration and recent test results.

Liposomal Drug Product Development and Quality: Current US Experience and Perspective.

Science.gov (United States)

Kapoor, Mamta; Lee, Sau L; Tyner, Katherine M

2017-05-01

Research in the area of liposomes has grown substantially in the past few decades. Liposomes are lipid bilayer structures that can incorporate drug substances to modify the drug's pharmacokinetic profile thereby improving drug delivery. The agency has received over 400 liposomal drug product submissions (excluding combination therapies), and there are currently eight approved liposomal drug products on the US market. In order to identify the pain points in development and manufacturing of liposomal drug products, a retrospective analysis was performed from a quality perspective on submissions for new and generic liposomal drug products. General analysis on liposomal drug product submissions was also performed. Results indicated that 96% of the submissions were Investigational New Drug (IND) applications, 3% were New Drug Applications (NDAs), and the remaining 1% was Abbreviated New Drug Applications (ANDAs). Doxorubicin hydrochloride was the most commonly used drug substance incorporated into the liposomes (31%). The majority of the liposomal products were administered via intravenous route (84%) with cancer (various types) being the most common indication (63%). From a quality perspective, major challenges during the development of liposomal drug products included identification and (appropriate) characterization of critical quality attributes of liposomal drug products and suitable control strategies during product development. By focusing on these areas, a faster and more efficient development of liposomal drug products may be achieved. Additionally, in this way, the drug review process for such products can be streamlined.

Does quality control matter? Surface urban heat island intensity variations estimated by satellite-derived land surface temperature products

Science.gov (United States)

Lai, Jiameng; Zhan, Wenfeng; Huang, Fan; Quan, Jinling; Hu, Leiqiu; Gao, Lun; Ju, Weimin

2018-05-01

The temporally regular and spatially comprehensive monitoring of surface urban heat islands (SUHIs) have been extremely difficult, until the advent of satellite-based land surface temperature (LST) products. However, these LST products have relatively higher errors compared to in situ measurements. This has resulted in comparatively inaccurate estimations of SUHI indicators and, consequently, may have distorted interpretations of SUHIs. Although reports have shown that LST qualities are important for SUHI interpretations, systematic investigations of the response of SUHI indicators to LST qualities across cities with dissimilar bioclimates are rare. To address this issue, we chose eighty-six major cities across mainland China and analyzed SUHI intensity (SUHII) derived from Moderate Resolution Imaging Spectroradiometer (MODIS) LST data. The LST-based SUHII differences due to inclusion or exclusion of MODIS quality control (QC) flags (i.e., ΔSUHII) were evaluated. Our major findings included, but are not limited to, the following four aspects: (1) SUHIIs can be significantly impacted by MODIS QC flags, and the associated QC-induced ΔSUHIIs generally accounted for 24.3% (29.9%) of the total SUHII value during the day (night); (2) the ΔSUHIIs differed between seasons, with considerable differences between transitional (spring and autumn) and extreme (summer and winter) seasons; (3) significant discrepancies also appeared among cities located in northern and southern regions, with northern cities often possessing higher annual mean ΔSUHIIs. The internal variations of ΔSUHIIs within individual cities also showed high heterogeneity, with ΔSUHII variations that generally exceeded 5.0 K (3.0 K) in northern (southern) cities; (4) ΔSUHIIs were negatively related to SUHIIs and cloud cover percentages (mostly in transitional seasons). No significant relationship was found in the extreme seasons. Our findings highlight the need to be extremely cautious when using LST

Multi-scale optical metrology for the quality control of polymer microfluidic systems

DEFF Research Database (Denmark)

Tosello, Guido; Marinello, Francesco; Hansen, Hans Nørgaard

2009-01-01

Micro injection moulding is a replication technology enabling large scale production of polymer-based micro products. To this respect, optical measuring technologies were selected to perform the quality control of a polymer micro-component: an optical coordinate measuring machine (CMM) and a white...

Improving Quality of Seal Leak Test Product using Six Sigma

Science.gov (United States)

Luthfi Malik, Abdullah; Akbar, Muhammad; Irianto, Dradjad

2016-02-01

Seal leak test part is a polyurethane material-based product. Based on past data, defect level of this product was 8%, higher than the target of 5%. Quality improvement effort was done using six sigma method that included phases of define, measure, analyse, improve, and control. In the design phase, a Delphi method was used to identify factors that were critical to quality. In the measure phase, stability and process capability was measured. Fault tree analysis (FTA) and failure mode and effect analysis (FMEA) were used in the next phase to analize the root cause and to determine the priority issues. Improve phase was done by compiling, selecting, and designing alternative repair. Some improvement efforts were identified, i.e. (i) making a checklist for maintenance schedules, (ii) making written reminder form, (iii) modifying the SOP more detail, and (iv) performing a major service to the vacuum machine. To ensure the continuity of improvement efforts, some control activities were executed, i.e. (i) controlling, monitoring, documenting, and setting target frequently, (ii) implementing reward and punishment system, (iii) adding cleaning tool, and (iv) building six sigma organizational structure.

Improving Quality of Seal Leak Test Product using Six Sigma

International Nuclear Information System (INIS)

Malik, Abdullah Luthfi; Akbar, Muhammad; Irianto, Dradjad

2016-01-01

Seal leak test part is a polyurethane material-based product. Based on past data, defect level of this product was 8%, higher than the target of 5%. Quality improvement effort was done using six sigma method that included phases of define, measure, analyse, improve, and control. In the design phase, a Delphi method was used to identify factors that were critical to quality. In the measure phase, stability and process capability was measured. Fault tree analysis (FTA) and failure mode and effect analysis (FMEA) were used in the next phase to analize the root cause and to determine the priority issues. Improve phase was done by compiling, selecting, and designing alternative repair. Some improvement efforts were identified, i.e. (i) making a checklist for maintenance schedules, (ii) making written reminder form, (iii) modifying the SOP more detail, and (iv) performing a major service to the vacuum machine. To ensure the continuity of improvement efforts, some control activities were executed, i.e. (i) controlling, monitoring, documenting, and setting target frequently, (ii) implementing reward and punishment system, (iii) adding cleaning tool, and (iv) building six sigma organizational structure. (paper)

Technological measures to improve automotive product quality

OpenAIRE

Gladkov, V.; Kruglov, S.

2010-01-01

The paper examines the basic technological measures aimed at improving product quality in automotive industry. While paying due attention to solving organizational and technological problems, including the development of certification systems for production processes, it is also necessary to improve the technical standards of specific technologies, equipment and materials as they largely determine product quality. Special emphasis is given to the importance of improving the production of auto...

Quality Dimensions of Purchase Behavior Decision on Fishery Products

Directory of Open Access Journals (Sweden)

Nurliza Nurliza

2017-08-01

Full Text Available The role of fishery product has been developed and acknowledged in terms of food security both as income sources and food supplies for developing countries. On the other hand, quality control has become a challenge in overcoming consumers’ decision to purchase the products. The objective of research is to understand and evaluate consumer behavior in purchasing the products in regards to quality dimension on fishery products by using non-probability sampling technique to 142 consumers in three different locations in Pontianak (shops, mini/supermarkets, and local markets. Data were gathered by in-depth interviews divided into four categories consisting of consumer profiles; product knowledge; perception and preference; and quality dimension variable with conjoint analysis. The result shows that price, flavor, moistness, texture, nutrition, packaging color, and packaging size do not affect consumers’ decision to purchase the products. On the contrary, package durability attribute is the primary factor in their decision to purchase, and it is then followed by packaging material, availability, flavor, guarantee, guarantee source, brand, packaging form, and product form. This is beneficial for producers to improve the quality factors and develop market opportunities in the future. Besides, consumers can obtain information on product characteristics to fulfill their expectation and satisfaction.Keywords: conjoint analysis, fishery products, non-probability sampling, purchase behavior, quality dimensionsABSTRAKPeran produk olahan perikanan telah berkembang dan diakui dalam keamanan pangan–baik sebagai sumber pendapatan maupun sumber makanan bagi negara-negara berkembang. Namun, pengendalian terhadap karakteristik mutu menjadi sebuah tantangan dalam menghadapi keputusan pembelian konsumen. Tujuan penelitian adalah memahami dan mengevaluasi perilaku keputusan pembelian konsumen terkait dimensi mutu pada produk olahan perikanan menggunakan teknik non

Quality costs in the production process

OpenAIRE

J. Michalska

2006-01-01

Purpose: The aim of this paper is showing the relationship of the quality costs with a production process. In this paper it was worked out and introduced the way of marking the documents with regard to the quality costs.Design/methodology/approach: In the frames of own research it has been analysed the quality costs in the production process from the documents marked using the worked out way of marking.Findings: On the basis of the own research it can be stated, that the majority of the eleme...

Integrated Application of Quality-by-Design Principles to Drug Product Development: A Case Study of Brivanib Alaninate Film-Coated Tablets.

Science.gov (United States)

Badawy, Sherif I F; Narang, Ajit S; LaMarche, Keirnan R; Subramanian, Ganeshkumar A; Varia, Sailesh A; Lin, Judy; Stevens, Tim; Shah, Pankaj A

2016-01-01

Modern drug product development is expected to follow quality-by-design (QbD) paradigm. At the same time, although there are several issue-specific examples in the literature that demonstrate the application of QbD principles, a holistic demonstration of the application of QbD principles to drug product development and control strategy, is lacking. This article provides an integrated case study on the systematic application of QbD to product development and demonstrates the implementation of QbD concepts in the different aspects of product and process design for brivanib alaninate film-coated tablets. Using a risk-based approach, the strategy for development entailed identification of product critical quality attributes (CQAs), assessment of risks to the CQAs, and performing experiments to understand and mitigate identified risks. Quality risk assessments and design of experiments were performed to understand the quality of the input raw materials required for a robust formulation and the impact of manufacturing process parameters on CQAs. In addition to the material property and process parameter controls, the proposed control strategy includes use of process analytical technology and conventional analytical tests to control in-process material attributes and ensure quality of the final product. Copyright © 2016. Published by Elsevier Inc.

40 CFR 51.359 - Quality control.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Quality control. 51.359 Section 51.359....359 Quality control. Quality control measures shall insure that emission testing equipment is calibrated and maintained properly, and that inspection, calibration records, and control charts are...

The construction of a quality system in the brazilian market of Organic Products

Directory of Open Access Journals (Sweden)

Djalma Eudes dos Santos

2016-11-01

Full Text Available http://dx.doi.org/10.5007/2175-7984.2016v15n33p131 Consumption of organic products in Brazil has acquired visibility and, more recently, has a comprehensive legal framework with regard to inclusion and recognition of other ways of producing, for example, apart from organic production, the agroecologic and the  extractivism. In this spectrum, the point of view on quality of food guiding the production, distribution and consumption becomes a key element for market consolidation and preservation of its characteristics as a differentiated way to produce. This article explains the origin of construction and imposition of quality standards for organic products through institutionalization of a conception of control, drawn with participation of the state, which seeks to equate a problem of stability in the market of organic products. This research explores the contours of this construction of a conception of control, featuring its participants, explaining its main discourses and forms of engagement.

Improvement by the Life Cycle Control System of University Production With Use of CALS-Tehnology

Directory of Open Access Journals (Sweden)

Yuriy I. Dreizis

2013-01-01

Full Text Available The mechanism of management by life cycle of production of university with use of CALS technologies is described. Tasks of service of marketing and the quality management department, connected with university product quality control are defined

Quality control on pre-serial Bridgman production of PbWO{sub 4} scintillating crystals by means of photoelasticity

Energy Technology Data Exchange (ETDEWEB)

Rinaldi, D., E-mail: d.rinaldi@univpm.i [Dipartimento di Fisica e Ingegneria dei Materiali e del Territorio, Universita Politecnica delle Marche, via Brecce Bianche, 60131 Ancona (Italy); INFN section of Perugia (Italy); Ciriaco, A. [Dipartimento di Fisica e Ingegneria dei Materiali e del Territorio, Universita' Politecnica delle Marche, via Brecce Bianche, 60131 Ancona (Italy); Lebeau, M. [CERN PH department, 1211 Geneva 23 (Switzerland); Paone, N. [Dipartimento di Meccanica, Universita' Politecnica delle Marche, via Brecce Bianche, 60131 Ancona (Italy)

2010-04-11

Residual internal stresses in PbWO{sub 4} (PWO) scintillating crystals grown by Bridgman method have been systematically studied. Residual stresses induced during growth play an important role in production yield. Cracking probability during mechanical processing as well as stable mechanical properties in finished crystal are closely related to internal stress levels. A regular production of good-quality crystals requires a fast and easy feed-back on growth parameters. Samples from a pre-serial production were analyzed in order to give the producer a quality feed-back for process optimization. By means of photoelasticity, we measured residual stress distribution in several sections along the growth axis and for typical positions in every section. The stress analysis revealed defects occurring during the crystallization process, attributed to dislocations, lattice disorientation and poly-crystallinity. This work had been prompted by the need for quality monitoring of a pre-serial production of PWO for the CMS experiment at CERN's LHC. Mapping stress levels inside the ingot volume and proposing a synthetic parameter to be used as a quality indicator, the resulting analysis should contribute to parameter optimization and improve the growth performance. The proposed method may be useful in conventional crystal production.

Nondestructive quality evaluation technology of agricultural products

International Nuclear Information System (INIS)

Noh, Sang Ha

1997-01-01

Quality evaluation of agricultural products has been interested to many researchers for many years and as the result, several nondestructive techniques and so many papers have been reported for quality evaluation of agricultural products. These nondestructive techniques are based on the detection of mechanical, optical, electrical, electro-magnetical, dielectric and vibrational properties of agricultural products that are well correlated with certain quality factors of the products such as color, shape, firmness, sugar content, external or internal defects, moisture content, etc. The sophistication of nondestructive methods has evolved rapidly with modem technologies. In this paper an emphasis was put on reviewing some of those papers and techniques which could be led to on-line measurement for practical use.

Citrus Quality Control: An NMR/MRI Problem-Based Experiment

Science.gov (United States)

Erhart, Sarah E.; McCarrick, Robert M.; Lorigan, Gary A.; Yezierski, Ellen J.

2016-01-01

An experiment seated in an industrial context can provide an engaging framework and unique learning opportunity for an upper-division physical chemistry laboratory. An experiment that teaches NMR/MRI through a problem-based quality control of citrus products was developed. In this experiment, using a problem-based learning (PBL) approach, students…

Batch-to-Batch Quality Consistency Evaluation of Botanical Drug Products Using Multivariate Statistical Analysis of the Chromatographic Fingerprint

OpenAIRE

Xiong, Haoshu; Yu, Lawrence X.; Qu, Haibin

2013-01-01

Botanical drug products have batch-to-batch quality variability due to botanical raw materials and the current manufacturing process. The rational evaluation and control of product quality consistency are essential to ensure the efficacy and safety. Chromatographic fingerprinting is an important and widely used tool to characterize the chemical composition of botanical drug products. Multivariate statistical analysis has showed its efficacy and applicability in the quality evaluation of many ...

Genetic and physiology basis of the quality of livestock products.

Directory of Open Access Journals (Sweden)

Marcello Mele

2011-02-01

Full Text Available The animal research gives more attention, for more than twenty years, to the improvement of food quality, because this aspect plays an important role in the consumer choice. In this paper are browsed the principal foods of animal origin (milk, meat and eggs, paying attention on the actual genetic and physiologic knowledge, which influence the quality characteristic. Particularly, we examined the role of Quantitative Genetic in bovine and swine and the growing knowledge about animal genomes and individuation of QTL. Information on genomic regions that control QTL, allow to organize genetic improvement programs, using Markers Assisted Selection (MAS and Markers Assisted Introgression (MAI. Moreover are reported the knowledge about metabolic processes that influence quality especially on lipid and protein component. About other productions are considered the physiology of eggs production and the genetic improvement of hens. Finally the qualitative aspects about poultry and rabbit meat and the actual genetic improvement strategy are reported.

Microbiological safety and quality control of poultry products sold in retail chains of Saint Petersburg and Leningrad region.

Directory of Open Access Journals (Sweden)

A. K. Alieva

2017-01-01

Full Text Available Food safety and food raw materials is an important task which needs to be under government’s and public associations’ control, under enterprises which produce and sale them, and other economy departments. Nutrition is one of the most important factors influencing human health. To 70% alien substances of chemical and microbiological origin get into the human body with food. The heavy metals, nitrates, nitrites, pesticides, nitrosescomounds, mycotoxins, antibiotics, radionuclides and others are xenobiotics of chemical origin. The poultry products represented in commercial networks by poultry plants located in Saint-Petersburg and Leningrad region: “Roskar”, “Sinyavinskaya”, “North”, “Lebyazhye” were picked up for analysis. We used the bacteriological, virological, immunological, mycological, and statistical methods of research. Sanitary -hygienic or microbiological safety of food products was evaluated for the contenting of disease-causing (pathogenic microorganisms such as bacteria groups, coliforms, Staphylococcus, Salmonella and etc. in them. The poultry products sold in commercial networks of St. Petersburg were picked up for analysis. After processing the statistical were revealed 6 nosological forms where the leading position has finding colibacillosis – 27%. The number of positive samples for streptococcosis – 18%, staphylococcus – 8%, aspergillosis–2.6%, salmonellosis – 1.8%, pasteurellosis–1.6 %. The microbiological control of food products which can be the sources of infections should be regular for providing inhabitants with harmless poultry products. It is necessary to adopt and to use the modern microbiological criteria of food safety that will allow to realize the monitoring of their conformity with sanitary norms. The results of these analysis shows that the quality of poultry products sold in commercial networks of Saint Petersburg and the Leningrad region meet the standards.

Influence of Wheat-Milled Products and Their Additive Blends on Pasta Dough Rheological, Microstructure, and Product Quality Characteristics

Directory of Open Access Journals (Sweden)

B. Dhiraj

2013-01-01

Full Text Available This study is aimed to assess the suitability of T. aestivum wheat milled products and its combinations with T. durum semolina with additives such as ascorbic acid, vital gluten and HPMC (Hydroxypropyl methyl cellulose for pasta processing quality characteristics such as pasta dough rheology, microstructure, cooking quality, and sensory evaluation. Rheological studies showed maximum dough stability in Comb1 (T. aestivum wheat flour and semolina. Colour and cooking quality of Comb2 (T. durum semolina and T. aestivum wheat flour and Comb3 (T. aestivum wheat semolina and T. durum semolina were comparable with control. Pasting results indicated that T. aestivum semolina gave the lowest onset gelatinization temperature (66.9°C but the highest peak viscosity (1.053 BU. Starch release was maximum in Comb1 (53.45% when compared with control (44.9% as also proved by microstructure studies. Firmness was seen to be slightly high in Comb3 (2.430 N when compared with control (2.304 N, and sensory evaluations were also in the acceptable range for the same. The present study concludes that Comb3 comprising 50% T. durum semolina and 50% T. aestivum refined wheat flour with additives would be optimal alternate for 100% T. durum semolina for production of financially viable pasta.

Possible approaches to fast quality control of IFE targets

International Nuclear Information System (INIS)

Koresheva, E.R.; Nikitenko, A.I.; Aleksandrova, I.V.; Bazdenkov, S.V.; Belolipetskiy, A.A.; Chtcherbakov, V.I.; Osipov, I.E.

2006-01-01

In recent years, research into the development of reliable methods and techniques for characterization and quality control of ICF/IFE targets has been carried out very actively. This is motivated by the need to provide the means for precise and accurate knowledge of cryogenic target parameters. On the other hand, particular emphasis should be paid to the fact that fuelling of a commercial power plant requires ∼6 targets each second. This indicates that the development of fast quality control techniques is of critical importance as well. Therefore, in this report we discuss the issues underlying the construction of different algorithms for characterization and quality control of ICF/IFE targets. Among them are: (a) algorithm banks and their structure, (b) algorithm testing, (c) target reconstruction experiments. The algorithm bank incorporates the algorithms for two stages of target production: the stage of fuel layering technique development (motionless target) and the stage of cryogenic target delivery (injected target). In the first case an inverse algorithm for individual target characterization (3D target reconstruction) and two threshold algorithms for fast control of target quality are presented. They are based on tomographic information processing methods. Experimentally, tomographic data acquisition is carried out by a hundred projections microtomograph. The spatial resolution of the optical system of the microtomograph is 1 μm for 490 nm wavelength, the accuracy of target angular positioning is ±1.5-2.5 min. In the second case we describe the algorithm based on Fourier transform holography for ultra fast target characterization during its injection. The performed computer experiments have demonstrated much promise of this approach in the following directions: recognition of the target imperfections in both low- and high- harmonics; quality control of both a single target and a target batch; simultaneous control of both an injected target quality and

Process and quality control in manufacturing of nuclear fuel assemblies of LWRs

International Nuclear Information System (INIS)

Dietrich, M.; Hoff, A.; Reimann, P.

2000-01-01

Manufacturing of nuclear fuel assemblies requires a multitude of different process and quality methods to assure and maintain a high quality level. In recent years methods have been applied which prevent deviations rather than detect deviant products. This paper gives an example on how to control a complex manufacturing process by using a small number of key parameters and second, it demonstrates the importance of graphical data evaluation and presentation methods. In the past many product and product characteristics were inspected m comparison with specification limits only. However, todays methods allow the early identification of trends, increase of variation, shifts disturbances etc. before the product characteristics exceed the specification limits. These methods are process control charts, x-y-plots, boxplots, failure mode and effect analysis (FMEA), process capability numbers and others. This paper demonstrates the beneficial use of some of the methods by presenting selected examples applied at Advanced Nuclear Fuels GmbH (ANF). (author)

Quality control in the development of coagulation factor concentrates.

Science.gov (United States)

Snape, T J

1987-01-01

Limitation of process change is a major factor contributing to assurance of quality in pharmaceutical manufacturing. This is particularly true in the manufacture of coagulation factor concentrates, for which presumptive testing for poorly defined product characteristics is an integral feature of finished product quality control. The development of new or modified preparations requires that this comfortable position be abandoned, and that the effect on finished product characteristics of changes to individual process steps (and components) be assessed. The degree of confidence in the safety and efficacy of the new product will be determined by, amongst other things, the complexity of the process alteration and the extent to which the results of finished product tests can be considered predictive. The introduction of a heat-treatment step for inactivation of potential viral contaminants in coagulation factor concentrates presents a significant challenge in both respects, quite independent of any consideration of assessment of the effectiveness of the viral inactivation step. These interactions are illustrated by some of the problems encountered with terminal dry heat-treatment (72 h. at 80 degrees C) of factor VIII and prothrombin complex concentrates manufactured by the Blood Products Laboratory.

21 CFR 111.110 - What quality control operations are required for laboratory operations associated with the...

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What quality control operations are required for laboratory operations associated with the production and process control system? 111.110 Section 111.110 Food... § 111.110 What quality control operations are required for laboratory operations associated with the...

27 CFR 27.75 - Samples of distilled spirits, wine, and beer for quality control purposes.

Science.gov (United States)

2010-04-01

... spirits, wine, and beer for quality control purposes. 27.75 Section 27.75 Alcohol, Tobacco Products and... DISTILLED SPIRITS, WINES, AND BEER General Requirements Exemptions § 27.75 Samples of distilled spirits, wine, and beer for quality control purposes. Samples of distilled spirits, wine, and beer in containers...

Green design for productivity, health and quality of life

Energy Technology Data Exchange (ETDEWEB)

Hartkopf, V. [Carnegie Mellon Univ., Pittsburgh, PA (United States). Center for Building Performance and Diagnostics

2005-07-01

The potential cost-benefits for quality construction of office buildings were discussed with particular reference to sick building costs and health building gains. Cost-benefits were indicated in terms of first cost, operational energy costs, individual productivity, organizational productivity, health, attraction, taxation, and waste. The measures of human response in buildings were also discussed with reference to comfort and satisfaction, individual productivity, health and absenteeism, attraction, spatial flexibility, motivation and collaboration. The building attributes that have the greatest impact include air, light, thermal control, ergonomics, privacy and interaction, access to nature, land use and mobility. It was suggested that natural ventilation should be maximized with mixed-mode heating, ventilating and air conditioning (HVAC) systems, and that ventilation air should be separate from thermal conditioning. It was also suggested that temperature control can increase productivity and reduce energy consumption. Several international case studies have shown that acoustic privacy also increases individual productivity at complex tasks. The presentation concluded by indicating that healthy and sustainable design also depends on changing approaches to land use and community planning in terms of pedestrian walkways, maximized loading of infrastructure and buildings, minimized abandonment and green roof development to reduce annual cooling loads. tabs., figs.

"Product on Stopper" in a Lyophilized Drug Product: Cosmetic Defect or a Product Quality Concern?

Science.gov (United States)

Mehta, Shyam B; Roy, Shouvik; Yang, Han-Chang Cathy

2018-06-01

During manufacturing of a lyophilized drug product, operator errors in product handling during loading of product filled vials onto the lyophilizer can lead to a seemingly cosmetic defect which can impact certain critical quality attributes of finished product. In this study, filling of a formulated monoclonal antibody in vials was performed using a peristaltic pump filling unit, and subsequently, the product was lyophilized. After lyophilization, upon visual inspection, around 40% of vials had cosmetic defect with residual product around stopper of the vial and were categorized as "product on stopper" vials, whereas remaining 60% vials with no cosmetic defect were called "acceptable vials." Both groups of vials from 1 single batch were tested for critical quality attributes including protein concentration (ultraviolet absorbance at 280), residual moisture (Karl Fischer), sterility (membrane filtration), and container closure integrity (CCI) (blue dye ingress). Analysis of protein quality attributes such as aggregation, protein concentration, residual moisture showed no significant difference between vials with "product on stopper" and "acceptable vials." However, CCI of the "product on stopper" vials was compromised due to the presence of product around stopper of the vial. The results from this case study demonstrate the following 2 important findings: (1) that a seemingly cosmetic defect may impact product quality, compromising the integrity of the product and (2) that CCI test method can be used as an orthogonal method to sterility testing to evaluate sterility assurance of the product. The corrective action proposed to mitigate this defect is use of a larger sized vial that can potentially minimize this defect that arises because of product handling errors. Copyright © 2018 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

Quality evaluation of resistivity-controlled silicon crystals

Science.gov (United States)

Wang, Jong Hoe

2006-01-01

The segregation phenomenon of dopants causes a low production yield of silicon crystal that meets the resistivity tolerance required by device manufacturers. In order to control the macroscopic axial resistivity distribution in bulk crystal growth, numerous studies including continuous Czochralski method and double crucible technique have been studied. The simple B-P codoping method for improving the productivity of p-type silicon single-crystal growth by controlling axial specific resistivity distribution was proposed by Wang [Jpn. J. Appl. Phys. 43 (2004) 4079]. In this work, the quality of Czochralski-grown silicon single crystals with a diameter 200 mm using B-P codoping method was studied from the chemical and structural points of view. It was found that the characteristics of B-P codoped wafers including the oxygen precipitation behavior and the grown-in defects are same as that of conventional B-doped Czochralski crystals.

Introduction of the new process and quality control methods in fuel fabrication at Siemens/ANF

International Nuclear Information System (INIS)

Rogge, K.T.; Fickers, H.H.; Doerr, W.

2000-01-01

The central point of ANFs quality philosophy is the process of continuous improvements. With respect to the causes of defects and the efforts needed for elimination, the importance of continuous improvements is evident. In most of the cases, defects are caused in the initial stages of a product but the majority of the problems will be only detected during fabrication and inspection and in the worst case when the product is already in use. Goal of the improvement process is to assure a high product quality. Therefore, the efforts are focused on robust and centered processes. A reasonable quality planning is the basis for achieving and maintaining the quality targets. Quality planning includes prefabrication studies, in-process inspections and final inspections. The inspections provide a large amount of various quality data, process parameters as well as product proper-ties. Key data will be defined and subjected to a statistical analysis. In view of the effectiveness of the analysis, it is important, that the process parameters which influence the characteristics of the product are well known and that appropriate methods for data evaluation and visualization will be used. Main approach of the data visualization is to obtain a tighter control of the product properties and to improve the process robustness by implementation of defined improvements. With respect to the fuel safety and fuel performance, the presentation shows for typical product quality characteristics some examples of visualized quality data. The examples includes the integrity of the pellet column (rod scanner results), the spring force of PWR spacers (critical characteristic with regard to rod fretting) and the spacer intersection weld size (thermo-hydraulic fuel bundle behaviour). The presentation also includes an example for the statistical process control, the in-line surveillance of the fuel rod weld parameters which assures the integrity of the welds within tight tolerance ranges. The quality

The role of production control in the development of burnout.

Science.gov (United States)

Houben, G J; Nijhuis, F J

1996-01-01

Burnout is an increasingly important problem in modern work organizations. Few studies, however, have explicitly applied an adequate theoretical understanding of the performance of modern organizations. This article aims to initiate both a discussion of this phenomenon and higher-quality research into the emergence of burnout based on an understanding of the economic-technological rationalization and control (management control) of production and service processes. In applying production control, both technical and bureaucratic, group and attitudinal control systems are increasingly integrated. This so-called systematic control strategy is one of the major causes of burnout. The cumulative effect of an increasing workload combined with reduced resources due to economic considerations and technocratic implementation of production control is assumed to be relevant to the development of burnout. The authors' propositions apply to service workers in human service organizations and to key workers in enterprises using flexible specialization combined with self-directed work groups.

Improving the quality of pork and pork products for the consumer : development of innovative, integrated, and sustainable food production chains of high quality pork products matching consumer demands

NARCIS (Netherlands)

Heimann, B.; Christensen, M.; Rosendal Rasmussen, S.; Bonneau, M.; Grunert, K.G.; Arnau, J.; Trienekens, J.H.; Oksbjerg, N.; Greef, de K.H.; Petersen, B.

2012-01-01

Improving the quality of pork and pork products for the consumer: development of innovative, integrated, and sustainable food production chains of high quality pork products matching consumer demands.

Drop-on-Demand System for Manufacturing of Melt-based Solid Oral Dosage: Effect of Critical Process Parameters on Product Quality.

Science.gov (United States)

Içten, Elçin; Giridhar, Arun; Nagy, Zoltan K; Reklaitis, Gintaras V

2016-04-01

The features of a drop-on-demand-based system developed for the manufacture of melt-based pharmaceuticals have been previously reported. In this paper, a supervisory control system, which is designed to ensure reproducible production of high quality of melt-based solid oral dosages, is presented. This control system enables the production of individual dosage forms with the desired critical quality attributes: amount of active ingredient and drug morphology by monitoring and controlling critical process parameters, such as drop size and product and process temperatures. The effects of these process parameters on the final product quality are investigated, and the properties of the produced dosage forms characterized using various techniques, such as Raman spectroscopy, optical microscopy, and dissolution testing. A crystallization temperature control strategy, including controlled temperature cycles, is presented to tailor the crystallization behavior of drug deposits and to achieve consistent drug morphology. This control strategy can be used to achieve the desired bioavailability of the drug by mitigating variations in the dissolution profiles. The supervisor control strategy enables the application of the drop-on-demand system to the production of individualized dosage required for personalized drug regimens.

Quality control in nuclear fuel fabrication on the inspection basis

International Nuclear Information System (INIS)

Fuentes S, A.

1997-01-01

Every plant productive of electric power requires the use of energetics for the transformation to electricity. In the nucleo electric plant the energetic is the uranium, in which it makes ensembles and is used as fuel in the reactor. To assure that the fuel ensembles fulfill the specifications and requirements of design stipulated in the nucleo electric plant is that under a quality control through inspections during the fabrication process. The purpose of this work is to study and verify that the lineaments of the standard 10 CFR 50 appendix B 'Quality assurement for nuclear plants' specially in the criteria 'Inspections' that is used to guarantee the quality of the ensembles. This standard is the one that rules every activity and operation inside the pilot plant and its established in the quality program in the production of nuclear fuel for the Laguna Verde plant. The quality of the assemble is verified through each one of the tests or inspections due to the importance of it in the fabrication of fuel. (Author)

7 CFR 981.42 - Quality control.

Science.gov (United States)

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Quality control. 981.42 Section 981.42 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Regulating Handling Quality Control § 981.42 Quality control. (a) Incoming. Except as provided in this...

Quality control of dosemeters

International Nuclear Information System (INIS)

Mendes, L.

1984-01-01

Nuclear medicine laboratories are required to assay samples of radioactivity to be administered to patients. Almost universally, these assays are acomplished by use of a well ionization chamber isotope calibrator. The Instituto de Radioprotecao e Dosimetria (Institute for Radiological Protection and Dosimetry) of the Comissao Nacional de Energia Nuclear (National Commission for Nuclear Energy) is carrying out a National Quality Control Programme in Nuclear Medicine, supported by the International Atomic Energy Agency. The assessment of the current needs and practices of quality control in the entire country of Brazil includes Dose Calibrators and Scintilation Cameras, but this manual is restricted to the former. Quality Control Procedures for these Instruments are described in this document together with specific recommendations and assessment of its accuracy. (Author) [pt

CryoSat product quality and evolutions

Science.gov (United States)

Bouffard, Jérome; Parrinello, Tommaso; Féménias, Pierre

2017-04-01

The main CryoSat mission objectives are to measure the regional and basin-scale changes in the thickness of the sea-ice and, in the elevation of the ice sheets and mountain glaciers. Beside its ice-monitoring objective, CryoSat also provides valuable observations for the oceanographic community. The CryoSat data are processed by ESA both over the ocean and ice surfaces with two independent processors. These data need to be routinely Quality-Controlled and thoroughly Validated (QCV). Based on the QCV outcomes from ESA multi-national partners and the feedback from the scientific community, the data products continuously evolve in order to accommodate a wide range of users over the Sea ice, the Land Ice and the Ocean domains. The main objectives of this paper are to give an overview of main CryoSat QCV results and product improvements; as well as to present the processing algorithm upgrades being implemented for future ice and ocean Baselines.

A Model of Risk Analysis in Analytical Methodology for Biopharmaceutical Quality Control.