WorldWideScience

Sample records for production line inspection

  1. Inspection logistics planning for multi-stage production systems with applications to semiconductor fabrication lines

    Science.gov (United States)

    Chen, Kyle Dakai

    Since the market for semiconductor products has become more lucrative and competitive, research into improving yields for semiconductor fabrication lines has lately received a tremendous amount of attention. One of the most critical tasks in achieving such yield improvements is to plan the in-line inspection sampling efficiently so that any potential yield problems can be detected early and eliminated quickly. We formulate a multi-stage inspection planning model based on configurations in actual semiconductor fabrication lines, specifically taking into account both the capacity constraint and the congestion effects at the inspection station. We propose a new mixed First-Come-First-Serve (FCFS) and Last-Come-First-Serve (LCFS) discipline for serving the inspection samples to expedite the detection of potential yield problems. Employing this mixed FCFS and LCFS discipline, we derive approximate expressions for the queueing delays in yield problem detection time and develop near-optimal algorithms to obtain the inspection logistics planning policies. We also investigate the queueing performance with this mixed type of service discipline under different assumptions and configurations. In addition, we conduct numerical tests and generate managerial insights based on input data from actual semiconductor fabrication lines. To the best of our knowledge, this research is novel in developing, for the first time in the literature, near-optimal results for inspection logistics planning in multi-stage production systems with congestion effects explicitly considered.

  2. Latest developments in on- and off-line inspection of bank notes during production

    Science.gov (United States)

    Brown, Stephen C.

    2004-06-01

    The inspection of bank notes is a highly labour intensive process where traditionally every note on every sheet is inspected manually. However with the advent of more and more sophisticated security features, both visible and invisible, and the requirement of cost reduction in the printing process, it is clear that automation is required. Machines for the automatic inspection of bank notes have been on the market for the past 10 to 12 years, but recent developments in technology have enabled a new generation of detectors and machines to be developed. This paper focuses on the latest developments in both the off-line and on-line inspection of bank notes covering not only the visible spectrum but also a new range of detectors for inspection some of the more common invisible features used as covert features in today's bank notes.

  3. Surface inspection of flat products by means of texture analysis: on-line implementation using neural networks

    Science.gov (United States)

    Fernandez, Carlos; Platero, Carlos; Campoy, Pascual; Aracil, Rafael

    1994-11-01

    This paper describes some texture-based techniques that can be applied to quality assessment of flat products continuously produced (metal strips, wooden surfaces, cork, textile products, ...). Since the most difficult task is that of inspecting for product appearance, human-like inspection ability is required. A common feature to all these products is the presence of non- deterministic texture on their surfaces. Two main subjects are discussed: statistical techniques for both surface finishing determination and surface defect analysis as well as real-time implementation for on-line inspection in high-speed applications. For surface finishing determination a Gray Level Difference technique is presented to perform over low resolution images, that is, no-zoomed images. Defect analysis is performed by means of statistical texture analysis over defective portions of the surface. On-line implementation is accomplished by means of neural networks. When a defect arises, textural analysis is applied which result in a data-vector, acting as input of a neural net, previously trained in a supervised way. This approach tries to reach on-line performance in automated visual inspection applications when texture is presented in flat product surfaces.

  4. Health products inspection

    International Nuclear Information System (INIS)

    Stoltz, M.

    2009-01-01

    To protect public health, the Health Products Inspection is a public service mission where the application of regulations concerning activities on human health products and cosmetic products is verified. This mission permits a global approach to assess the health products risk-based benefit and, in monitoring by laboratory testing and by on site inspections, to verify their compliance with appropriate regulations. The seventy five inspectors perform about eight hundred inspections per year, in France and abroad. These inspections are related to data provided in the health products assessment and also to manufacturing and delivery practices. The French inspection body is also involved in the training of foreign inspectors and in the harmonization of national, European and international practices either for operators than for the competent authorities. (author)

  5. Conceptual design for transmission line inspection robot

    International Nuclear Information System (INIS)

    Jalal, M F Abdul; Sahari, K S Mohamed; Anuar, A; Arshad, A D Mohd; Idris, M S

    2013-01-01

    Power transmission line is used for power distribution purposes due to their cost effective measure compared to underlying cable. However, prolonged exposure to natural weather may cause fatigue stress to the lines as well as induce material failure. Therefore, periodical line inspection is considered uttermost important as a preventive measure to avoid power outage. However, transmission line inspection has always been a high risk and expensive work. Hazardous works that may harm operator as well as routine that requires precise handling can be performed by robots. Various types of robots have been designed and developed for line inspection but only perform well on a straight and continuous line. As these robots encounter an obstacle during the inspection, then the real problem in terms of robot stability and smooth operation arises. In this paper, conceptual design and evaluation for transmission line inspection robot is presented. The inspection robot mobile robot must be able to bypass or avoid obstacles as it travels along the power transmission line.

  6. production lines

    Directory of Open Access Journals (Sweden)

    Jingshan Li

    2000-01-01

    Full Text Available In this work, serial production lines with finished goods buffers operating in the pull regime are considered. The machines are assumed to obey Bernoulli reliability model. The problem of satisfying customers demand is addressed. The level of demand satisfaction is quantified by the due-time performance (DTP, which is defined as the probability to ship to the customer a required number of parts during a fixed time interval. Within this scenario, the definitions of DTP bottlenecks are introduced and a method for their identification is developed.

  7. Machine vision systems using machine learning for industrial product inspection

    Science.gov (United States)

    Lu, Yi; Chen, Tie Q.; Chen, Jie; Zhang, Jian; Tisler, Anthony

    2002-02-01

    Machine vision inspection requires efficient processing time and accurate results. In this paper, we present a machine vision inspection architecture, SMV (Smart Machine Vision). SMV decomposes a machine vision inspection problem into two stages, Learning Inspection Features (LIF), and On-Line Inspection (OLI). The LIF is designed to learn visual inspection features from design data and/or from inspection products. During the OLI stage, the inspection system uses the knowledge learnt by the LIF component to inspect the visual features of products. In this paper we will present two machine vision inspection systems developed under the SMV architecture for two different types of products, Printed Circuit Board (PCB) and Vacuum Florescent Displaying (VFD) boards. In the VFD board inspection system, the LIF component learns inspection features from a VFD board and its displaying patterns. In the PCB board inspection system, the LIF learns the inspection features from the CAD file of a PCB board. In both systems, the LIF component also incorporates interactive learning to make the inspection system more powerful and efficient. The VFD system has been deployed successfully in three different manufacturing companies and the PCB inspection system is the process of being deployed in a manufacturing plant.

  8. Line-scan inspection of conifer seedlings

    Science.gov (United States)

    Rigney, Michael P.; Kranzler, Glenn A.

    1993-05-01

    Almost two billion conifer seedlings are produced in the U.S. each year to support reforestation efforts. Seedlings are graded manually to improve viability after transplanting. Manual grading is labor-intensive and subject to human variability. Our previous research demonstrated the feasibility of automated tree seedling inspection with machine vision. Here we describe a system based on line-scan imaging, providing a three-fold increase in resolution and inspection rate. A key aspect of the system is automatic recognition of the seedling root collar. Root collar diameter, shoot height, and projected shoot and root areas are measured. Sturdiness ratio and shoot/root ratio are computed. Grade is determined by comparing measured features with pre-defined set points. Seedlings are automatically sorted. The precision of machine vision and manual measurements was determined in tests at a commercial forest nursery. Manual measurements of stem diameter, shoot height, and sturdiness ratio had standard deviations three times those of machine vision measurements. Projected shoot area was highly correlated (r2 equals 0.90) with shoot volume. Projected root area had good correlation (r2 equals 0.80) with root volume. Seedlings were inspected at rates as high as ten per second.

  9. 241-AY-102 Leak Detection Pit Drain Line Inspection Report

    International Nuclear Information System (INIS)

    Boomer, Kayle D.; Engeman, Jason K.; Gunter, Jason R.; Joslyn, Cameron C.; Vazquez, Brandon J.; Venetz, Theodore J.; Garfield, John S.

    2014-01-01

    This document provides a description of the design components, operational approach, and results from the Tank AY-102 leak detection pit drain piping visual inspection. To perform this inspection a custom robotic crawler with a deployment device was designed, built, and operated by IHI Southwest Technologies, Inc. for WRPS to inspect the 6-inch leak detection pit drain line

  10. An ultrasonic inspection tool for production tubulars

    Energy Technology Data Exchange (ETDEWEB)

    Newton, K; Martin, R; Ravenscroft, F [AEA Technology, Harwell (United Kingdom)

    1994-06-01

    Advances in ultrasonic technology, high temperature techniques and remote processing power are enabling a new generation of inspection tools to be developed. This paper describes a particular new ultrasonic caliper system, developed by AEA Technology, with the aim of providing improved information about the condition of production tubulars of oil and gas wells. The system is designed to provide enhanced surface area coverage compared to the current devices, which are typically mechanical 'finger' calipers. It also provides a non-contacting measure of corrosion and wear together with direct on-line output and automated data analysis. The new tool is designed to operate in oil and gas, vertical or deviated wells and has the potential for modification to inspect small diameter pipes in topside or other plant. (author)

  11. INFIBRA: machine vision inspection of acrylic fiber production

    Science.gov (United States)

    Davies, Roger; Correia, Bento A. B.; Contreiras, Jose; Carvalho, Fernando D.

    1998-10-01

    This paper describes the implementation of INFIBRA, a machine vision system for the inspection of acrylic fiber production lines. The system was developed by INETI under a contract from Fisipe, Fibras Sinteticas de Portugal, S.A. At Fisipe there are ten production lines in continuous operation, each approximately 40 m in length. A team of operators used to perform periodic manual visual inspection of each line in conditions of high ambient temperature and humidity. It is not surprising that failures in the manual inspection process occurred with some frequency, with consequences that ranged from reduced fiber quality to production stoppages. The INFIBRA system architecture is a specialization of a generic, modular machine vision architecture based on a network of Personal Computers (PCs), each equipped with a low cost frame grabber. Each production line has a dedicated PC that performs automatic inspection, using specially designed metrology algorithms, via four video cameras located at key positions on the line. The cameras are mounted inside custom-built, hermetically sealed water-cooled housings to protect them from the unfriendly environment. The ten PCs, one for each production line, communicate with a central PC via a standard Ethernet connection. The operator controls all aspects of the inspection process, from configuration through to handling alarms, via a simple graphical interface on the central PC. At any time the operator can also view on the central PC's screen the live image from any one of the 40 cameras employed by the system.

  12. UAV Low Altitude Photogrammetry for Power Line Inspection

    Directory of Open Access Journals (Sweden)

    Yong Zhang

    2017-01-01

    Full Text Available When the distance between an obstacle and a power line is less than the discharge distance, a discharge arc can be generated, resulting in the interruption of power supplies. Therefore, regular safety inspections are necessary to ensure the safe operation of power grids. Tall vegetation and buildings are the key factors threatening the safe operation of extra high voltage transmission lines within a power line corridor. Manual or laser intensity direction and ranging (LiDAR based inspections are time consuming and expensive. To make safety inspections more efficient and flexible, a low-altitude unmanned aerial vehicle (UAV remote-sensing platform, equipped with an optical digital camera, was used to inspect power line corridors. We propose a semi-patch matching algorithm based on epipolar constraints, using both the correlation coefficient (CC and the shape of its curve to extract three dimensional (3D point clouds for a power line corridor. We use a stereo image pair from inter-strip to improve power line measurement accuracy by transforming the power line direction to an approximately perpendicular to epipolar line. The distance between the power lines and the 3D point cloud is taken as a criterion for locating obstacles within the power line corridor automatically. Experimental results show that our proposed method is a reliable, cost effective, and applicable way for practical power line inspection and can locate obstacles within the power line corridor with accuracy better than ±0.5 m.

  13. 9 CFR 590.925 - Inspection of imported egg products.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Inspection of imported egg products... AGRICULTURE EGG PRODUCTS INSPECTION INSPECTION OF EGGS AND EGG PRODUCTS (EGG PRODUCTS INSPECTION ACT) Imports § 590.925 Inspection of imported egg products. (a) Except as provided in § 590.960, egg products offered...

  14. International cooperation in production inspections

    International Nuclear Information System (INIS)

    Limousin, S.

    2009-01-01

    Nuclear pressure equipment, like the reactor pressure vessel or steam generators, are manufactured in many countries all around the world. As only few reactors were built in the 90's, most of the nuclear safety authorities have lost part of their know how in component manufacturing oversight. For these two reasons, vendor inspection is a key area for international cooperation. On the one hand, ASN has bilateral relationships with several countries (USA, Finland, China...) to fulfill specific purposes. On the other hand, ASN participates in international groups like the MDEP ( Multinational Design Evaluation Program). A MDEP working group dedicated to vendor inspection cooperation enables exchanges of informations (inspection program plan, inspection findings...) among the regulators. Join inspections are organized. International cooperation could lead in the long term to an harmonization of regulatory practices. (author)

  15. Product line design

    Czech Academy of Sciences Publication Activity Database

    Anderson, S. P.; Celik, Levent

    2015-01-01

    Roč. 157, May (2015), s. 517-526 ISSN 0022-0531 Institutional support: RVO:67985998 Keywords : product line design * product differentiation * second-degree price discrimination Subject RIV: AH - Economics Impact factor: 1.097, year: 2015

  16. Mini-Uav LIDAR for Power Line Inspection

    Science.gov (United States)

    Teng, G. E.; Zhou, M.; Li, C. R.; Wu, H. H.; Li, W.; Meng, F. R.; Zhou, C. C.; Ma, L.

    2017-09-01

    Light detection and ranging (LIDAR) system based on unmanned aerial vehicles (UAVs) recently are in rapid advancement, meanwhile portable and flexible mini-UAV-borne laser scanners have been a hot research field, especially for the complex terrain survey in the mountains and other areas. This study proposes a power line inspection system solution based on mini-UAV-borne LIDAR system-AOEagle, developed by Academy of Opto-Electronics, Chinese Academy of Sciences, which mounted on a Multi-rotor unmanned aerial vehicle for complex terrain survey according to real test. Furthermore, the point cloud data was explored to validate its applicability for power line inspection, in terms of corridor and line laser point clouds; deformation detection of power towers, etc. The feasibility and advantages of AOEagle have been demonstrated by the promising results based on the real-measured data in the field of power line inspection.

  17. 9 CFR 318.309 - Finished product inspection.

    Science.gov (United States)

    2010-01-01

    ... Section 318.309 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY... Canning and Canned Products § 318.309 Finished product inspection. (a) Finished product inspections must...

  18. 9 CFR 381.309 - Finished product inspection.

    Science.gov (United States)

    2010-01-01

    ... Section 381.309 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION POULTRY PRODUCTS INSPECTION REGULATIONS Canning and Canned Products § 381.309...

  19. 9 CFR 355.21 - Products entering inspected plants.

    Science.gov (United States)

    2010-01-01

    ... INSPECTION AND CERTIFICATION CERTIFIED PRODUCTS FOR DOGS, CATS, AND OTHER CARNIVORA; INSPECTION... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Products entering inspected plants. 355.21 Section 355.21 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF...

  20. Product line design

    Czech Academy of Sciences Publication Activity Database

    Anderson, S. P.; Celik, Levent

    2015-01-01

    Roč. 157, May (2015), s. 517-526 ISSN 0022-0531 R&D Projects: GA ČR(CZ) GA15-22540S Institutional support: PRVOUK-P23 Keywords : product line design * product differentiation * second-degree price discrimination Subject RIV: AH - Economics Impact factor: 1.097, year: 2015

  1. Assessing and preparing a pipeline for in line inspection

    Energy Technology Data Exchange (ETDEWEB)

    Payne, Larry [T.D. Williamson Inc., Tulsa, OK (United States)

    2003-07-01

    In today's pipeline environment, operators around the world face new and emerging state and federal regulations requiring validation of their pipelines' integrity. In line inspection, or smart pigging, is generally the preferred methodology used to investigate metal loss and corrosion in pipelines. Although many pipelines can accommodate smart pigging, there are many pipelines that cannot, for various reasons. Those reasons can vary from not having pig launchers and receivers installed on the line to impassable bends or restrictions and general cleanliness of the pipeline itself. Pipeline cleanliness, more times than not, is one of the main reasons for inaccurate in line inspection data gathering or failed smart pig runs. (author)

  2. Developing Green Line Products

    DEFF Research Database (Denmark)

    Muñoz-Marin, Ana Maria; Lassen, Astrid Heidemann; Poulsen, Søren Bolvig

    2011-01-01

    This publication is based on the Master thesis “User-driven ecoinnovation process: Towards the implementation of the Green product line at JELD-WEN” written by Ana Maria Muñoz-Marin as her Graduation Project for the MSc. Global Innovation Management degree. The company-based experiment was carried...

  3. A Novel Method of Autonomous Inspection for Transmission Line based on Cable Inspection Robot LiDAR Data

    Directory of Open Access Journals (Sweden)

    Xinyan Qin

    2018-02-01

    Full Text Available With the growth of the national economy, there is increasing demand for electricity, which forces transmission line corridors to become structurally complicated and extend to complex environments (e.g., mountains, forests. It is a great challenge to inspect transmission line in these regions. To address these difficulties, a novel method of autonomous inspection for transmission line is proposed based on cable inspection robot (CIR LiDAR data, which mainly includes two steps: preliminary inspection and autonomous inspection. In preliminary inspection, the position and orientation system (POS data is used for original point cloud dividing, ground point filtering, and structured partition. A hierarchical classification strategy is established to identify the classes and positions of the abnormal points. In autonomous inspection, CIR can autonomously reach the specified points through inspection planning. These inspection targets are imaged with PTZ (pan, tilt, zoom cameras by coordinate transformation. The feasibility and effectiveness of the proposed method are verified by test site experiments and actual line experiments, respectively. The proposed method greatly reduces manpower and improves inspection accuracy, providing a theoretical basis for intelligent inspection of transmission lines in the future.

  4. Research on UAV Intelligent Obstacle Avoidance Technology During Inspection of Transmission Line

    Science.gov (United States)

    Wei, Chuanhu; Zhang, Fei; Yin, Chaoyuan; Liu, Yue; Liu, Liang; Li, Zongyu; Wang, Wanguo

    Autonomous obstacle avoidance of unmanned aerial vehicle (hereinafter referred to as UAV) in electric power line inspection process has important significance for operation safety and economy for UAV intelligent inspection system of transmission line as main content of UAV intelligent inspection system on transmission line. In the paper, principles of UAV inspection obstacle avoidance technology of transmission line are introduced. UAV inspection obstacle avoidance technology based on particle swarm global optimization algorithm is proposed after common obstacle avoidance technologies are studied. Stimulation comparison is implemented with traditional UAV inspection obstacle avoidance technology which adopts artificial potential field method. Results show that UAV inspection strategy of particle swarm optimization algorithm, adopted in the paper, is prominently better than UAV inspection strategy of artificial potential field method in the aspects of obstacle avoidance effect and the ability of returning to preset inspection track after passing through the obstacle. An effective method is provided for UAV inspection obstacle avoidance of transmission line.

  5. Review of techniques for on-line monitoring and inspection of laser welding

    International Nuclear Information System (INIS)

    Shao, J; Yan, Y

    2005-01-01

    Laser welding has been applied to various industries, in particular, automotive, aerospace and microelectronics. However, traditional off-line testing of the welds is costly and inefficient. Therefore, on-line inspection systems with low cost have being developed to increase productivity and maintain high welding quality. This paper presents the applications of acoustic, optical, visual, thermal and ultrasonic techniques and latest development of laser welding monitoring. The advantages and limitations of these techniques are also discussed

  6. MODULAR RESEARCH EQUIPMENT FOR ON-LINE INSPECTION IN ADVANCED MANUFACTURING SYSTEMS

    Directory of Open Access Journals (Sweden)

    Davrajh, S.

    2012-11-01

    Full Text Available The significance of inspection processes increases when producing parts with high levels of customer input. These processes must adapt to variations in significant product characteristics. Mass customisation and reconfigurable manufacturing are currently being researched as ways to respond to high levels of customer input. This paper presents the research and development of modular inspection equipment that was designed to meet the on-line quality requirements of mass customisation and reconfigurable manufacturing environments. Simulated results were analysed for application in an industrial environment. The implementation of the equipment in South Africa is briefly discussed. The research indicates that manufacturers need only invest in the required equipment configurations when they are needed for on-line inspection.

  7. Strategic production line synchronisation

    Directory of Open Access Journals (Sweden)

    Hattingh, Teresa

    2016-08-01

    Full Text Available A study was conducted at the sole global producer of suspension struts for a particular vehicle manufacturer. This supplier is currently able to meet customer demand. However, it does so because of a large finished goods and work-in-progress (WIP inventory. The plant operates two production processes that are separated by a large buffer of WIP, which essentially decouples the production processes. This study aimed to reduce this WIP buffer; this would require the processes to become synchronised, bearing in mind that the reliability of delivery should not decrease. A tool that considers time, quality, and machine capacity was developed to assess the impact of line synchronisation on company performance figures. It was found that line synchronisation produced several benefits for the supplier, including batch size reduction, lower inventory levels, and associated shorter lead times. This further allowed the supplier to improve flow in the plant by introducing a pull system. Improved visual oversight could lead to further improved problem-solving and innovation.

  8. Basic performance metrics of in-line inspection tools

    Energy Technology Data Exchange (ETDEWEB)

    Timashev, Sviatoslav A. [Russian Academy of Sciences (Russian Federation). Ural Branch. Science and Engineering Center

    2003-07-01

    The paper discusses current possibilities and drawbacks of in-line inspection (ILI) in detecting, identifying, locating and sizing of all types of defects in oil and gas pipelines. A full set of consistent and universal ILI tool performance metrics is constructed. A holistic methodology that extracts maximum value from the ILI measurements in defect detecting, locating, identifying, sizing and verifying the results of ILI is presented. The outlined approach is being implemented as a software component of a multi-purpose HR MFL ILI tool and is proposed for the new API 1163 ILI Qualification Standard. (author)

  9. On-line monitoring and inservice inspection in codes

    International Nuclear Information System (INIS)

    Bartonicek, J.; Zaiss, W.; Bath, H.R.

    1999-01-01

    The relevant regulatory codes determine the ISI tasks and the time intervals for recurrent components testing for evaluation of operation-induced damaging or ageing in order to ensure component integrity on the basis of the last available quality data. In-service quality monitoring is carried out through on-line monitoring and recurrent testing. The requirements defined by the engineering codes elaborated by various institutions are comparable, with the KTA nuclear engineering and safety codes being the most complete provisions for quality evaluation and assurance after different, defined service periods. German conventional codes for assuring component integrity provide exclusively for recurrent inspection regimes (mainly pressure tests and optical testing). The requirements defined in the KTA codes however always demanded more specific inspections relying on recurrent testing as well as on-line monitoring. Foreign codes for ensuring component integrity concentrate on NDE tasks at regular time intervals, with time intervals scope of testing activities being defined on the basis of the ASME code, section XI. (orig./CB) [de

  10. Real-time line-width measurements: a new feature for reticle inspection systems

    Science.gov (United States)

    Eran, Yair; Greenberg, Gad; Joseph, Amnon; Lustig, Cornel; Mizrahi, Eyal

    1997-07-01

    The significance of line width control in mask production has become greater with the lessening of defect size. There are two conventional methods used for controlling line widths dimensions which employed in the manufacturing of masks for sub micron devices. These two methods are the critical dimensions (CD) measurement and the detection of edge defects. Achieving reliable and accurate control of line width errors is one of the most challenging tasks in mask production. Neither of the two methods cited above (namely CD measurement and the detection of edge defects) guarantees the detection of line width errors with good sensitivity over the whole mask area. This stems from the fact that CD measurement provides only statistical data on the mask features whereas applying edge defect detection method checks defects on each edge by itself, and does not supply information on the combined result of error detection on two adjacent edges. For example, a combination of a small edge defect together with a CD non- uniformity which are both within the allowed tolerance, may yield a significant line width error, which will not be detected using the conventional methods (see figure 1). A new approach for the detection of line width errors which overcomes this difficulty is presented. Based on this approach, a new sensitive line width error detector was developed and added to Orbot's RT-8000 die-to-database reticle inspection system. This innovative detector operates continuously during the mask inspection process and scans (inspects) the entire area of the reticle for line width errors. The detection is based on a comparison of measured line width that are taken on both the design database and the scanned image of the reticle. In section 2, the motivation for developing this new detector is presented. The section covers an analysis of various defect types, which are difficult to detect using conventional edge detection methods or, alternatively, CD measurements. In section 3

  11. 9 CFR 590.24 - Egg products plants requiring continuous inspection.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Egg products plants requiring..., DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION INSPECTION OF EGGS AND EGG PRODUCTS (EGG PRODUCTS INSPECTION ACT) Scope of Inspection § 590.24 Egg products plants requiring continuous inspection. No plant in...

  12. A development of an automated ultrasonic TOFD inspection system using an welding line tracing robot

    International Nuclear Information System (INIS)

    Cho, Hyun; Song, Sung Jin; Lee, Kang Won; Kim, Young Jin; Woo, Jong Sik

    2006-01-01

    Large scaled ships, manufactured inside of the country, should be passed welding inspection and painting film inspection. Normally, these kind of inspections are conducted by human inspectors manually, although it cause industrial disasters such as falling accidents and diving accidents frequently. In addition, Ship makers are not to give a full trust to shipowners because manual inspections cannot be conducted all over the welding parts. So, in this study we developed an automated ultrasonic TOFD inspection system using an welding line tracing robot. This system, controlled by an inspector at a remote field, can inspect welding parts of ship outer panel both under water and in air. In this paper we present the developed robot and ultrasonic TOFD inspection system and the inspection result.

  13. A development of an automated ultrasonic TOFD inspection system using an welding line tracing robot

    International Nuclear Information System (INIS)

    Cho, Hyun; Song, Sung Jin; Lee, Kang Won; Kim, Young Jin; Woo, Jong Sik

    2006-01-01

    Large scaled ships, manufactured inside of the country, should be passed welding inspection and painting film inspection. Normally, these kind of inspections are conducted by human inspectors manually, although it cause industrial disasters such as falling accidents and diving accidents frequently. In addition, Ship makers are not to give a full trust to ship owners because manual inspections cannot be conducted all over the welding parts. So, in this study we developed an automated ultrasonic TOFD inspection system using an welding line tracing robot. This system, controlled by an inspector at a remote field, can inspect welding parts of ship outer panel both under water and in air. In this paper we present the developed robot and ultrasonic TOFD inspection system and the inspection result.

  14. Machine vision based quality inspection of flat glass products

    Science.gov (United States)

    Zauner, G.; Schagerl, M.

    2014-03-01

    This application paper presents a machine vision solution for the quality inspection of flat glass products. A contact image sensor (CIS) is used to generate digital images of the glass surfaces. The presented machine vision based quality inspection at the end of the production line aims to classify five different glass defect types. The defect images are usually characterized by very little `image structure', i.e. homogeneous regions without distinct image texture. Additionally, these defect images usually consist of only a few pixels. At the same time the appearance of certain defect classes can be very diverse (e.g. water drops). We used simple state-of-the-art image features like histogram-based features (std. deviation, curtosis, skewness), geometric features (form factor/elongation, eccentricity, Hu-moments) and texture features (grey level run length matrix, co-occurrence matrix) to extract defect information. The main contribution of this work now lies in the systematic evaluation of various machine learning algorithms to identify appropriate classification approaches for this specific class of images. In this way, the following machine learning algorithms were compared: decision tree (J48), random forest, JRip rules, naive Bayes, Support Vector Machine (multi class), neural network (multilayer perceptron) and k-Nearest Neighbour. We used a representative image database of 2300 defect images and applied cross validation for evaluation purposes.

  15. Bovine Spongiform Encephalopathy: Production and Inspection

    Science.gov (United States)

    ... are condemned and not allowed into the human food supply. The brains from animals that exhibit signs of neurological impairment during inspection are submitted for testing and analysis by the USDA's National Veterinary Services Laboratories. [ Top of Page ] What kind of testing ...

  16. High-radiance LDP source for mask inspection and beam line applications (Conference Presentation)

    Science.gov (United States)

    Teramoto, Yusuke; Santos, Bárbara; Mertens, Guido; Kops, Ralf; Kops, Margarete; von Wezyk, Alexander; Bergmann, Klaus; Yabuta, Hironobu; Nagano, Akihisa; Ashizawa, Noritaka; Taniguchi, Yuta; Yamatani, Daiki; Shirai, Takahiro; Kasama, Kunihiko

    2017-04-01

    High-throughput actinic mask inspection tools are needed as EUVL begins to enter into volume production phase. One of the key technologies to realize such inspection tools is a high-radiance EUV source of which radiance is supposed to be as high as 100 W/mm2/sr. Ushio is developing laser-assisted discharge-produced plasma (LDP) sources. Ushio's LDP source is able to provide sufficient radiance as well as cleanliness, stability and reliability. Radiance behind the debris mitigation system was confirmed to be 120 W/mm2/sr at 9 kHz and peak radiance at the plasma was increased to over 200 W/mm2/sr in the recent development which supports high-throughput, high-precision mask inspection in the current and future technology nodes. One of the unique features of Ushio's LDP source is cleanliness. Cleanliness evaluation using both grazing-incidence Ru mirrors and normal-incidence Mo/Si mirrors showed no considerable damage to the mirrors other than smooth sputtering of the surface at the pace of a few nm per Gpulse. In order to prove the system reliability, several long-term tests were performed. Data recorded during the tests was analyzed to assess two-dimensional radiance stability. In addition, several operating parameters were monitored to figure out which contributes to the radiance stability. The latest model that features a large opening angle was recently developed so that the tool can utilize a large number of debris-free photons behind the debris shield. The model was designed both for beam line application and high-throughput mask inspection application. At the time of publication, the first product is supposed to be in use at the customer site.

  17. Inspection Robot Based Mobile Sensing and Power Line Tracking for Smart Grid

    Directory of Open Access Journals (Sweden)

    Bat-erdene Byambasuren

    2016-02-01

    Full Text Available Smart sensing and power line tracking is very important in a smart grid system. Illegal electricity usage can be detected by remote current measurement on overhead power lines using an inspection robot. There is a need for accurate detection methods of illegal electricity usage. Stable and correct power line tracking is a very prominent issue. In order to correctly track and make accurate measurements, the swing path of a power line should be previously fitted and predicted by a mathematical function using an inspection robot. After this, the remote inspection robot can follow the power line and measure the current. This paper presents a new power line tracking method using parabolic and circle fitting algorithms for illegal electricity detection. We demonstrate the effectiveness of the proposed tracking method by simulation and experimental results.

  18. Inspection Robot Based Mobile Sensing and Power Line Tracking for Smart Grid.

    Science.gov (United States)

    Byambasuren, Bat-Erdene; Kim, Donghan; Oyun-Erdene, Mandakh; Bold, Chinguun; Yura, Jargalbaatar

    2016-02-19

    Smart sensing and power line tracking is very important in a smart grid system. Illegal electricity usage can be detected by remote current measurement on overhead power lines using an inspection robot. There is a need for accurate detection methods of illegal electricity usage. Stable and correct power line tracking is a very prominent issue. In order to correctly track and make accurate measurements, the swing path of a power line should be previously fitted and predicted by a mathematical function using an inspection robot. After this, the remote inspection robot can follow the power line and measure the current. This paper presents a new power line tracking method using parabolic and circle fitting algorithms for illegal electricity detection. We demonstrate the effectiveness of the proposed tracking method by simulation and experimental results.

  19. Contribution to the study of an on line inspection system for pulsed Nd:YAG laser welding operations

    International Nuclear Information System (INIS)

    Charton, Stephane

    1999-01-01

    This thesis deals with the study of a on line inspection system for pulsed Nd 3+ :YAG laser welding operations. During a welding operation, laser-material interaction results in the emission of signals (optical, acoustical, electrical, thermal), characteristic of its behavior. On line inspection is based on the hypothesis that the signals evolutions, measured by sensors such as photodiodes, microphones.., may be correlated with the welding defects. Laser weld quality inspection can be done by the machine qualification (before and during welding), and by on line monitoring of the welding operation. The similarity of the signals produced by pulsed lasers (machine or interaction) has led us to develop a specific data acquisition and processing software. Signal processing tools utilization (Fourier and wavelets transforms) in conjunction with classification techniques (stress polytopes), introduces an innovating on line inspection approach. Discriminant parameters determination (signals/defect correlation) becomes thus automatic and non subjective. The developed prototype is not dedicated to the detection of a particular defect because the classification operator is a supervised one and needs a learning phase. lt has been validated on welding defects which are easy to deal with, and then applied to a precise production control at the Nuclear Fabrications and Technology Division of the Valduc Center of the French Atomic Energy Agency. (author) [fr

  20. 9 CFR 381.209 - Returned United States inspected and marked poultry products; exemption.

    Science.gov (United States)

    2010-01-01

    ... PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION POULTRY PRODUCTS INSPECTION REGULATIONS... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Returned United States inspected and marked poultry products; exemption. 381.209 Section 381.209 Animals and Animal Products FOOD SAFETY AND...

  1. 9 CFR 381.197 - Imported products; foreign inspection certificates required.

    Science.gov (United States)

    2010-01-01

    ... AND VOLUNTARY INSPECTION AND CERTIFICATION POULTRY PRODUCTS INSPECTION REGULATIONS Imported Poultry... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Imported products; foreign inspection certificates required. 381.197 Section 381.197 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE...

  2. 9 CFR 381.199 - Inspection of poultry products offered for entry.

    Science.gov (United States)

    2010-01-01

    ... AND VOLUNTARY INSPECTION AND CERTIFICATION POULTRY PRODUCTS INSPECTION REGULATIONS Imported Poultry... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Inspection of poultry products offered for entry. 381.199 Section 381.199 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE...

  3. 9 CFR 590.920 - Importer to make application for inspection of imported eggs and egg products.

    Science.gov (United States)

    2010-01-01

    ... inspection of imported eggs and egg products. 590.920 Section 590.920 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION INSPECTION OF EGGS AND EGG PRODUCTS (EGG PRODUCTS INSPECTION ACT) Imports § 590.920 Importer to make application for inspection of...

  4. Applying ultrasonic in-line inspection technology in a deep water environment: exploring the challenges

    Energy Technology Data Exchange (ETDEWEB)

    Thielager, N.; Nadler, M.; Pieske, M.; Beller, M. [NDT Systems and Services AG, Stutensee (Germany)

    2009-12-19

    The demand for higher inspection accuracies of in-line inspection tools (ILI tools) is permanently growing. As integrity assessment procedures are being refined, detection performances, sizing accuracies and confidence levels regarding detection and sizing play an ever increasing role. ILI tools utilizing conventional ultrasound technology are at the forefront of technology and fulfill the market requirements regarding sizing accuracies and the ability to provide quantitative measurements of wall thickness as well as crack inspection capabilities. Data from ultrasonic tools is ideally suited for advanced integrity assessment applications and run comparisons. Making this technology available for a deep-water environment of heavy wall, high pressures and temperatures comes with a wide range of challenges which have to be addressed. This paper will introduce developments recently made in order to adapt and modify ultrasonic in-line inspection tools for the application in a heavy wall, high pressure and high temperature environment as encountered in deep offshore pipelines. The paper will describe necessary design modifications and new conceptual approaches especially regarding tool electronics, cables, connectors and the sensor carrier. A tool capable of deep-water inspection with a pressure bearing capability of 275 bar will be introduced and data from inspection runs will be presented. As an outlook, the paper will also discuss future inspection requirements for offshore pipelines with maximum pressure values of up to 500 bar. (author)

  5. 9 CFR 592.320 - Products that may bear the inspection mark.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Products that may bear the inspection... Marking Products § 592.320 Products that may bear the inspection mark. Products that are permitted to bear... products eligible to bear the inspection mark and may contain other edible ingredients. The official mark...

  6. 46 CFR 160.077-23 - Production tests and inspections.

    Science.gov (United States)

    2010-10-01

    ... fixed anchor, or (C) a tensile test machine that is capable of holding a given tension. The assembly... testing of each incoming lot of inflation chamber material before using that lot in production; (iii) Have... inspector must perform or supervise testing and inspection of at least one PFD lot in each five lots...

  7. Structural assessment procedure of corroding submarine gas pipelines using on-line inspection data

    International Nuclear Information System (INIS)

    Nordin Yahaya

    2000-01-01

    This paper presents 'the alternative approach of overall procedure in the assessment of corroded pipelines using data gathered by the on-line inspection device. The methodology adopts a generalised approach of analysing pipeline inspection data and a prediction of the structural reliability due to the deteriorating corrosion environment. The whole assessment methodology is divided into four separate stages; 1 to IV. Stages 1 and 11 are the initial procedure prior to the actual analysis of the inspection data. The scope of this paper is concerted into the procedure to be taken in Stage 111 where the stage is sub-divided into 3 major steps; Part A, B and C. These procedures are Part A (statistical and probabilistic analysis of the inspection data) and Part B (the application of extreme value statistics) and C (reliability assessment). Stage IV (risk assessment) is the final step in the procedure where the consequences of failure are evaluated. The proposed risk-based assessment procedure is more systematic and reliable to account for a huge amount of collected data usually obtained in an on-line inspection using the intelligent devices. The outcomes of this risk-based methodology can be very useful in the decision-making process by the operation management. This in turn will produce an efficient inspection, repair and maintenance program and enhanced the optimised return in investment. (author)

  8. AUTOMATED INSPECTION OF POWER LINE CORRIDORS TO MEASURE VEGETATION UNDERCUT USING UAV-BASED IMAGES

    Directory of Open Access Journals (Sweden)

    M. Maurer

    2017-08-01

    Full Text Available Power line corridor inspection is a time consuming task that is performed mostly manually. As the development of UAVs made huge progress in recent years, and photogrammetric computer vision systems became well established, it is time to further automate inspection tasks. In this paper we present an automated processing pipeline to inspect vegetation undercuts of power line corridors. For this, the area of inspection is reconstructed, geo-referenced, semantically segmented and inter class distance measurements are calculated. The presented pipeline performs an automated selection of the proper 3D reconstruction method for on the one hand wiry (power line, and on the other hand solid objects (surrounding. The automated selection is realized by performing pixel-wise semantic segmentation of the input images using a Fully Convolutional Neural Network. Due to the geo-referenced semantic 3D reconstructions a documentation of areas where maintenance work has to be performed is inherently included in the distance measurements and can be extracted easily. We evaluate the influence of the semantic segmentation according to the 3D reconstruction and show that the automated semantic separation in wiry and dense objects of the 3D reconstruction routine improves the quality of the vegetation undercut inspection. We show the generalization of the semantic segmentation to datasets acquired using different acquisition routines and to varied seasons in time.

  9. Automated Inspection of Power Line Corridors to Measure Vegetation Undercut Using Uav-Based Images

    Science.gov (United States)

    Maurer, M.; Hofer, M.; Fraundorfer, F.; Bischof, H.

    2017-08-01

    Power line corridor inspection is a time consuming task that is performed mostly manually. As the development of UAVs made huge progress in recent years, and photogrammetric computer vision systems became well established, it is time to further automate inspection tasks. In this paper we present an automated processing pipeline to inspect vegetation undercuts of power line corridors. For this, the area of inspection is reconstructed, geo-referenced, semantically segmented and inter class distance measurements are calculated. The presented pipeline performs an automated selection of the proper 3D reconstruction method for on the one hand wiry (power line), and on the other hand solid objects (surrounding). The automated selection is realized by performing pixel-wise semantic segmentation of the input images using a Fully Convolutional Neural Network. Due to the geo-referenced semantic 3D reconstructions a documentation of areas where maintenance work has to be performed is inherently included in the distance measurements and can be extracted easily. We evaluate the influence of the semantic segmentation according to the 3D reconstruction and show that the automated semantic separation in wiry and dense objects of the 3D reconstruction routine improves the quality of the vegetation undercut inspection. We show the generalization of the semantic segmentation to datasets acquired using different acquisition routines and to varied seasons in time.

  10. Replacement and inspection policies for products with random life cycle

    International Nuclear Information System (INIS)

    Yun, Won Young; Nakagawa, Toshio

    2010-01-01

    In this paper, we consider maintenance policies for products in which the economical life cycle of products is a random variable. First, we study a periodic replacement policy with minimal repair. The system is minimally repaired at failure and is replaced by new one at age T (periodic replacement policy with minimal repair of Barlow and Hunter). The expected present value of total maintenance cost of products with random life cycle is obtained and the optimal replacement interval minimizing the cost is found. Second, we consider an inspection policy for products with random life cycle to detect the system failure. The expected total cost is obtained and the optimal inspection interval is found. Numerical examples are also included.

  11. EUV mask defect inspection and defect review strategies for EUV pilot line and high volume manufacturing

    Science.gov (United States)

    Chan, Y. David; Rastegar, Abbas; Yun, Henry; Putna, E. Steve; Wurm, Stefan

    2010-04-01

    Reducing mask blank and patterned mask defects is the number one challenge for extreme ultraviolet lithography. If the industry succeeds in reducing mask blank defects at the required rate of 10X every year for the next 2-3 years to meet high volume manufacturing defect requirements, new inspection and review tool capabilities will soon be needed to support this goal. This paper outlines the defect inspection and review tool technical requirements and suggests development plans to achieve pilot line readiness in 2011/12 and high volume manufacturing readiness in 2013. The technical specifications, tooling scenarios, and development plans were produced by a SEMATECH-led technical working group with broad industry participation from material suppliers, tool suppliers, mask houses, integrated device manufacturers, and consortia. The paper summarizes this technical working group's assessment of existing blank and mask inspection/review infrastructure capabilities to support pilot line introduction and outlines infrastructure development requirements and tooling strategies to support high volume manufacturing.

  12. Simulation Design for Off-Line Training of Practical Lean Manufacturing Concepts for Visual Inspection

    Science.gov (United States)

    Tetteh, Edem; McWilliams, Douglas

    2010-01-01

    Customer needs for high-quality goods and the risk of product-liability litigation against businesses have made companies look for a way to sustain quality assurance in their products and services. Lean manufacturing is the latest and most successful system being used by companies to turn their business around. Visual inspection plays an important…

  13. 14 CFR 21.125 - Production inspection system: Materials Review Board.

    Science.gov (United States)

    2010-01-01

    ... § 21.125 Production inspection system: Materials Review Board. Link to an amendment published at 74 FR... Materials Review Board action for at least two years. (b) The production inspection system required in § 21... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Production inspection system: Materials...

  14. 9 CFR 312.3 - Official marks and devices to identify inspected and passed equine products.

    Science.gov (United States)

    2010-01-01

    ... inspected and passed equine products. 312.3 Section 312.3 Animals and Animal Products FOOD SAFETY AND... § 312.3 Official marks and devices to identify inspected and passed equine products. (a) The official... § 317.2 of this subchapter to identify inspected and passed mule and other (nonhorse) equine carcasses...

  15. 9 CFR 381.191 - Distribution of inspected products to small lot buyers.

    Science.gov (United States)

    2010-01-01

    ... small lot buyers. 381.191 Section 381.191 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE...; Exportation; or Sale of Poultry or Poultry Products § 381.191 Distribution of inspected products to small lot... small lot buyers (such as small restaurants), distributors or jobbers may remove inspected and passed...

  16. Product Line Rivalry with Brand Differentiation

    OpenAIRE

    Gilbert, Richard J.; Matutes, Carmen

    1989-01-01

    Competition with product rivalry is examined in a model where products are differentiated by both quality and brand name. With no commitment, firms produce a full product line. When firms can commit to restrict their product offerings, firms specialize if the degree of brand-specific differentiation is small and they produce a full product line if brand-specific differentiation is large relative to intrafirm differentiation. Firms may crowd a product space when all competitors would be better...

  17. Literature Review: Theory and Application of In-Line Inspection Technologies for Oil and Gas Pipeline Girth Weld Defection

    Science.gov (United States)

    Feng, Qingshan; Li, Rui; Nie, Baohua; Liu, Shucong; Zhao, Lianyu; Zhang, Hong

    2016-01-01

    Girth weld cracking is one of the main failure modes in oil and gas pipelines; girth weld cracking inspection has great economic and social significance for the intrinsic safety of pipelines. This paper introduces the typical girth weld defects of oil and gas pipelines and the common nondestructive testing methods, and systematically generalizes the progress in the studies on technical principles, signal analysis, defect sizing method and inspection reliability, etc., of magnetic flux leakage (MFL) inspection, liquid ultrasonic inspection, electromagnetic acoustic transducer (EMAT) inspection and remote field eddy current (RFDC) inspection for oil and gas pipeline girth weld defects. Additionally, it introduces the new technologies for composite ultrasonic, laser ultrasonic, and magnetostriction inspection, and provides reference for development and application of oil and gas pipeline girth weld defect in-line inspection technology. PMID:28036016

  18. Application of non-destructive liner thickness measurement technique for manufacturing and inspection process of zirconium lined cladding tube

    International Nuclear Information System (INIS)

    Nakazawa, Norio; Fukuda, Akihiro; Fujii, Noritsugu; Inoue, Koichi

    1986-01-01

    Recently, in order to meet the difference of electric power demand owing to electric power situation, large scale load following operation has become necessary. Therefore, the development of the cladding tubes which withstand power variation has been carried out, as the result, zirconium-lined zircaloy 2 cladding tubes have been developed. In order to reduce the sensitivity to stress corrosion cracking, these zirconium-lined cladding tubes require uniform liner thickness over the whole surface and whole length. Kobe Steel Ltd. developed the nondestructive liner thickness measuring technique based on ultrasonic flaw detection technique and eddy current flaw detection technique. These equipments were applied to the manufacturing and inspection processes of the zirconium-lined cladding tubes, and have demonstrated superiority in the control and assurance of the liner thickness of products. Zirconium-lined cladding tubes, the development of the measuring technique for guaranteeing the uniform liner thickness and the liner thickness control in the manufacturing and inspection processes are described. (Kako, I.)

  19. A Product Line Enhanced Unified Process

    DEFF Research Database (Denmark)

    Zhang, Weishan; Kunz, Thomas

    2006-01-01

    The Unified Process facilitates reuse for a single system, but falls short handling multiple similar products. In this paper we present an enhanced Unified Process, called UPEPL, integrating the product line technology in order to alleviate this problem. In UPEPL, the product line related activit...... activities are added and could be conducted side by side with other classical UP activities. In this way both the advantages of Unified Process and software product lines could co-exist in UPEPL. We show how to use UPEPL with an industrial mobile device product line in our case study....

  20. Applying TPM on Production Line of Huanwei

    Directory of Open Access Journals (Sweden)

    Zhai Yunkai

    2017-01-01

    The study based on the study and analysis of the TPM theory, based on my practice in the SMT2 production line of Victoria Electronics of Huanwei. Then it studied the promotion and implementation steps of TPM on SMT2 line. And it also introduced the improvement instance of SMT2 line. By contrasting the utilization of equipment on SMT2 line before and after the comprehensive of TPM, the necessity of implementing TPM is derived. For how to apply TPM on the production lines, and how to improve equipment comprehensive utilization, finish the order on time, provide high quality products to our customers, these are the main part of production line equipment management work. This article provides the reference for how to promote TPM on other production lines.

  1. Sustainable evolution of product line infrastructure code

    OpenAIRE

    Patzke, T.

    2011-01-01

    A major goal in many software development organizations today is to reduce development effort and cost, while improving their products' quality and diversity by developing reusable software. An organization takes advantage of its products' similarities, exploits what they have in common and manages what varies among them by building a product line infrastructure. A product line infrastructure is a reuse repository that contains exactly those common and variable artifacts, such as requirements...

  2. Applying TPM on Production Line of Huanwei

    OpenAIRE

    Zhai Yunkai; Zhang Jing

    2017-01-01

    As customers increasingly focus on the quality, cost, delivery time of the product, therefore the production line needs to improve production efficiency, improve product quality, which requires the introduction of a management system. The TPM (Total Productive maintenance) as a starting point to maintain the equipment, maintenance activities through full participation in the maintenance, increase productivity, reduce production costs. The study based on the study and analysis of the TPM th...

  3. Pipeline mapping and strain assessment using ILI (In-line Inspection) tolls

    Energy Technology Data Exchange (ETDEWEB)

    Purvis, Brian [GE PII Pipeline Solutions, Rio de Janeiro, RJ (Brazil); Huewener, Thomas [E.ON Ruhrgas AG, Essen (Germany)

    2009-07-01

    GE PII IMU Mapping inspection system measures pipeline location coordinates (x, y, z) and provides data for determining pipeline curvature and consequential pipeline bending strain. The changes in strain can be used in the application of structural analyses and integrity evaluation of pipeline systems. This paper reviews the Inertia Measuring Unit (IMU) system and field investigation works performed on a high-pressure gas pipeline for E.ON Ruhrgas AG. The Inertial Measuring Unit of the pipeline inspection tool provides continuous measurement of the pipeline centreline coordinates. More than one inspection run was performed which allowed a more accurate strain comparison to be made. Repeatability is important to establish the reasons for increasing strain values detected at specific pipeline sections through in-line inspection surveys conducted in regular intervals over many years. Moreover, the flexibility resulting from a combination of different sensor technologies, makes it possible to provide a more complete picture of the overall situation. This paper reviews the work involved in detecting, locating and determining the magnitude and type of strain corresponding to the pipeline movement in field. (author)

  4. A study on non-contact ultrasonic technique for on-line inspection of CFRP

    International Nuclear Information System (INIS)

    Lee, Seung-Joon; Park, Won-Su; Lee, Joon-Hyun; Byun, Joon-Hyung

    2007-01-01

    The advantages of carbon fiber reinforced plastic materials (CFRP) are: they are light structure materials, they have corrosion resistance, and higher specific strength and elasticity. The recently developed 3-dimentional fiber placement system is able to produce a more complex and various shaped structures due to less limitations of a product shape according to the problem in conventional fabrication process. This fiber placement system stacks the narrow prepreg tape on the mold according to the designed sequence and thickness. Non-destructive evaluation was rquired for these composites to evaluate changes in strength caused by defects such as delamination and porosity. Additionally, the expectent quality should be satisfied for the high cost fabrication process using the fiber placement system. Therefore, an on line non-destructive evaluation system is required and real-time complement is needed when the defects are detected [1]. Defect imaging by the ultrasonic C-scan method is a useful technique for defect detection in CFRP. However, the conventional ultrasonic C-scan technique cannot be applied during the fabrication process because the test piece should be immersed into the water. Therefore, non-contact ultrasonic techniques should be applied during the fabricating process. For the development of non-contact ultrasonic techniques available in non-destructive evaluation of CFRP, a recent laser-generated ultrasonic technique and an air-coupled transducer that transmit and receive ultrasounds in the air are studied [2-3]. In this study, generating and receiving techniques of laser-generated ultrasound and the characteristics of received signals upon the internal defects of CFRO were studied for non-contact inspection

  5. Multivariate image analysis for quality inspection in fish feed production

    DEFF Research Database (Denmark)

    Ljungqvist, Martin Georg

    Aquaculture is today one of the fastest growing food producing sectors in the world. Access to good and effective fish feed is a condition for optimised and sustainable aquaculture activity. In the aquaculture industry it is of utmost importance that the fish get feed of proper size and nutrition....... The colour appearance of fish products is important for customers. Salmonid fish get their red colour from a natural pigment called astaxanthin. To ensure a similar red colour of fish in aquaculture astaxanthin is used as an additive coated on the feed pellets. Astaxanthin can either be of natural origin......, or synthesised chemically. Common for both types is that they are relatively expensive in comparison to the other feed ingredients. This thesis investigates multi-variate data collection for visual inspection and optimisation of industrial production in the fish feed industry. Quality parameters focused on here...

  6. 78 FR 19182 - Electronic Filing of Import Inspection Applications for Meat, Poultry, and Egg Products...

    Science.gov (United States)

    2013-03-29

    ...] Electronic Filing of Import Inspection Applications for Meat, Poultry, and Egg Products: Availability of..., and egg products through the Automated Commercial Environment (ACE). ACE is the Web- based portal for... products (21 U.S.C. 620, 466). The Egg Products Inspection Act (EPIA) (21 U.S.C. 1031 et seq.) prohibits...

  7. Statistical analysis of real ILI (In-Line Inspection) data: implications, inferences and lessons learned

    Energy Technology Data Exchange (ETDEWEB)

    Timashev, Svyatoslav A.; Bushinskaya, Anna V. [Russian Academy of Sciences, Ekaterinburg (Russian Federation). Ural Branch. Sciences and Engineering Center ' Reliability and Safety of Large Systems and Machines'

    2009-07-01

    The paper discusses current possibilities and drawbacks of in-line inspection (ILI) in sizing defects in oil and gas pipelines. A methodology based on analysis of variances (ANOVA) is presented that extracts maximum possible information from the ILI measurements of defects and subsequent verification results. This full statistical analysis (FSA) methodology was extensively tested by using the Monte Carlo simulation method. It was then applied to analyze the content of sections 7, 9 and appendix E of the API 1163 RP Standard. (author)

  8. Introducing Product Lines through Open Source Tools

    OpenAIRE

    Haugen, Øystein

    2008-01-01

    We present an approach to introducing product lines to companies that lower their initial risk by applying open source tools and a smooth learning curve into the use and creation of domain specific modeling combined with standardized variability modeling.

  9. Magnetic imaging and machine vision NDT for the on-line inspection of stainless steel strips

    International Nuclear Information System (INIS)

    Ricci, M; Ficola, A; Fravolini, M L; Battaglini, L; Palazzi, A; Burrascano, P; Valigi, P; Appolloni, L; Cervo, S; Rocchi, C

    2013-01-01

    An on-line inspection system for stainless steel strips has been developed on an annealing and pickling line at the Acciai Speciali Terni S.p.A. steel mill. Besides a machine vision apparatus, the system contextually exploits a magnetic imaging system designed and realized for the specific application. The main goal of the research is represented by the fusion of the information provided by the two apparatuses that can improve the detection and classification tasks by enlarging the set of detectable defects. In this paper, the development, the calibration and the characteristics of the magnetic imaging apparatus are detailed and experimental results obtained both in laboratory and in situ are reported. A comparative analysis of the performances of the two devices is also reported based on preliminary results and some conclusions and perspectives are drawn. (paper)

  10. In line inspection of multi-diameter and high-pressure pipelines in Brazil using combined technologies: magnetic flux leakage and ultrasonic testing

    Energy Technology Data Exchange (ETDEWEB)

    Ginten, Markus; Brockhaus, Stephan; Bouaoua, Nourreddine; Klein, Stefan [ROSEN Technology and Research Center, Lingen (Germany); Bruening, Franz [ROSEN Brazil, Rio de Janeiro, RJ (Brazil)

    2009-07-01

    The simultaneous use of the magnetic flux leakage (MFL) method and the ultrasonic testing (UT) method on a single in line inspection (ILI) tool has been identified as a versatile and accurate solution for liquid pipelines. The combination of the two methods is complementary to the restrictions of each other. Also, the overall scope of the inspection is enlarged. General wall thinning and largely corroded areas are accurately and reliably scanned with the UT unit, while very detailed information about pitting corrosion is obtained from the MFL measurement. Blind spots of echo loss, as occasionally observed for the UT channels is compensated by the more robust measurement from the MFL sensors. Consequently, this technology has been the method of choice in an in line inspection project of an onshore long distance pipeline in Brazil, facing a variety of corrosion threats. The pipeline consists of several multi-diameter sections of 18/20 inches and 20/22 inches. Furthermore, the high gravity of product in combination with a height profile, an altitude of 1152 m MSL (Mean Sea Level) had to be crossed, leads to a maximum pressure of 220 bar. These boundary conditions had to be considered during the design of the ILI-tool. The paper discusses the experience made so far with the combined technology MFL and UT. The effective use of the inspection tool for the above mentioned pipeline as well as field results from a previous inspection are described. (author)

  11. METHODOLOGY AND ALGORITHM OF OPTIMIZATION OF THE NEED OF SETTLEMENTS FOR TECHNICAL INSPECTION LINES FOR VEHICLES

    Directory of Open Access Journals (Sweden)

    Maslennikov Valeriy Aleksandrovich

    2016-06-01

    Full Text Available The current methods of predicting the demand of the community for the lines of technical inspection of vehicles do not fully take into account the probabilistic and statistical nature of the complaints of car owners. This results in significant mistakes in the determination of the number of such lines, accompanied by insufficient rhythm of their operation. The design errors related to the complexity of accurate account for calendar fluctuations of the number of appeals can be partially or completely eliminated by using mathematical apparatus of the queuing theory. In this case, the complex technical system is considered as an open multi-channel queuing system with limited queue length. The received flows and serviced requests are considered to be the simplest. From a practical point of view, the replacement of one type of computational model by the other allows ensuring a more sustainable mode of calculating operations using the computer. The paper also provides a calculation expression for defining the lower and upper confidence limits of the dispersion of the average values of the number of arrivals of vehicles at the technical inspection that allows setting the interval of uncertainty for searching the optimal solution.

  12. 77 FR 70714 - Electronic Import Inspection Application and Certification of Imported Products and Foreign...

    Science.gov (United States)

    2012-11-27

    ... Import Inspection Application and Certification of Imported Products and Foreign Establishments..., the egg products import regulations provide for foreign country (not establishment) certification to... imported egg products at this time. The Agency will propose foreign establishment certification in a...

  13. Statistical Model Checking for Product Lines

    DEFF Research Database (Denmark)

    ter Beek, Maurice H.; Legay, Axel; Lluch Lafuente, Alberto

    2016-01-01

    average cost of products (in terms of the attributes of the products’ features) and the probability of features to be (un)installed at runtime. The product lines must be modelled in QFLan, which extends the probabilistic feature-oriented language PFLan with novel quantitative constraints among features...

  14. 46 CFR 160.176-15 - Production tests and inspections.

    Science.gov (United States)

    2010-10-01

    ... known weight and winch, (B) a scale, winch, and fixed anchor, or (C) a tensile test machine that is... laboratory inspector tests and inspects the lot; (ii) Perform required testing of each incoming lot of... produced the components used in the lifejacket. (d) Samples. (1) Samples used in testing and inspections...

  15. Safety in the design of production lines

    DEFF Research Database (Denmark)

    Dyhrberg, Mette Bang; Broberg, Ole; Jacobsen, Peter

    2006-01-01

    This paper is a case study report on how safety considerations were handled in the process of redesigning a production line. The design process was characterized as a specification and negotiation process between engineers from the company and the supplier organization. The new production line...... in the specification material nor in their face-to-face meetings with the supplier. Safety aspects were not part of their work practice. On this basis, it was suggested that formal guidelines or procedures for integrating safety in the design of production lines would have no effect. Instead, the researchers set up...... became safer, but not as a result of any intentional plan to integrate safety aspects into the design process. Instead, the supplier’s design of a new piece of equipment had a higher built-in safety level. The engineering team in the company was aware of the importance of safety aspects neither...

  16. Safety in the redesigning of production lines

    DEFF Research Database (Denmark)

    Dyhrberg, Mette Bang; Broberg, Ole; Jacobsen, Peter

    2006-01-01

    This paper is a case study report on how safety considerations were handled in the process of redesigning a production line. The design process was characterized as a specification and negotiation process between engineers from the company and the supplier organization. The new production line...... became safer, but not as a result of any intentional plan to integrate safety aspects into the design process. Instead, the supplier’s design of a new piece of equipment had a higher built-in safety level. The engineering team in the company was aware of the importance of safety aspects neither...... in the specification material nor in their face-to-face meetings with the supplier. Safety aspects were not part of their work practice. On this basis, it was suggested that formal guidelines or procedures for integrating safety in the design of production lines would have no effect. Instead, the researchers set up...

  17. 9 CFR 381.198 - Importer to make application for inspection of poultry products offered for entry.

    Science.gov (United States)

    2010-01-01

    ... MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION POULTRY PRODUCTS... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Importer to make application for inspection of poultry products offered for entry. 381.198 Section 381.198 Animals and Animal Products FOOD...

  18. 9 CFR 381.204 - Marking of poultry products offered for entry; official import inspection marks and devices.

    Science.gov (United States)

    2010-01-01

    ... Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION POULTRY PRODUCTS... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Marking of poultry products offered...

  19. Wavefront holoscopy: application of digital in-line holography for the inspection of engraved marks in progressive addition lenses.

    Science.gov (United States)

    Perucho, Beatriz; Micó, Vicente

    2014-01-01

    Progressive addition lenses (PALs) are engraved with permanent marks at standardized locations in order to guarantee correct centering and alignment throughout the manufacturing and mounting processes. Out of the production line, engraved marks provide useful information about the PAL as well as act as locator marks to re-ink again the removable marks. Even though those marks should be visible by simple visual inspection with the naked eye, engraving marks are often faint and weak, obscured by scratches, and partially occluded and difficult to recognize on tinted or antireflection-coated lenses. Here, we present an extremely simple optical device (named as wavefront holoscope) for visualization and characterization of permanent marks in PAL based on digital in-line holography. Essentially, a point source of coherent light illuminates the engraved mark placed just before a CCD camera that records a classical Gabor in-line hologram. The recorded hologram is then digitally processed to provide a set of high-contrast images of the engraved marks. Experimental results are presented showing the applicability of the proposed method as a new ophthalmic instrument for visualization and characterization of engraved marks in PALs.

  20. Autonomous Inspection Robot for Power Transmission Lines Maintenance While Operating on the Overhead Ground Wires

    Directory of Open Access Journals (Sweden)

    Zheng Li

    2010-12-01

    Full Text Available This paper describes the development of a mobile robot capable of clearing such obstacles as counterweights, anchor clamps, and torsion tower. The mobile robot walks on overhead ground wires in 500KV power tower. Its ultimate purpose is to automate to inspect the defect of power transmission line. The robot with 13 motors is composed of two arms, two wheels, two claws, two wrists, etc. Each arm has 4 degree of freedom. Claws are also mounted on the arms. An embedded computer based on PC/104 is chosen as the core of control system. Visible light and thermal infrared cameras are installed to obtain the video and temperature information, and the communication system is based on wireless LAN TCP/IP protocol. A prototype robot was developed with careful considerations of mobility. The new sensor configuration is used for the claw to grasp the overhead ground wires. The bridge is installed in the torsion tower for the robot easy to cross obstacles. The new posture plan is proposed for obstacles cleaning in the torsion tower. Results of experiments demonstrate that the robot can be applied to execute the navigation and inspection tasks.

  1. Autonomous Inspection Robot for Power Transmission Lines Maintenance While Operating on the Overhead Ground Wires

    Directory of Open Access Journals (Sweden)

    Zheng Li

    2011-01-01

    Full Text Available This paper describes the development of a mobile robot capable of clearing such obstacles as counterweights, anchor clamps, and torsion tower. The mobile robot walks on overhead ground wires in 500KV power tower. Its ultimate purpose is to automate to inspect the defect of power transmission line. The robot with 13 motors is composed of two arms, two wheels, two claws, two wrists, etc. Each arm has 4 degree of freedom. Claws are also mounted on the arms. An embedded computer based on PC/104 is chosen as the core of control system. Visible light and thermal infrared cameras are installed to obtain the video and temperature information, and the communication system is based on wireless LAN TCP/IP protocol. A prototype robot was developed with careful considerations of mobility. The new sensor configuration is used for the claw to grasp the overhead ground wires. The bridge is installed in the torsion tower for the robot easy to cross obstacles. The new posture plan is proposed for obstacles cleaning in the torsion tower. Results of experiments demonstrate that the robot can be applied to execute the navigation and inspection tasks.

  2. Flight route Designing and mission planning Of power line inspecting system Based On multi-sensor UAV

    International Nuclear Information System (INIS)

    Xiaowei, Xie; Zhengjun, Liu; Zhiquan, Zuo

    2014-01-01

    In order to obtain various information of power facilities such as spatial location, geometry, images data and video information in the infrared and ultraviolet band and so on, Unmanned Aerial Vehicle (UAV) power line inspecting system needs to integrate a variety of sensors for data collection. Low altitude and side-looking imaging are required for UAV flight to ensure sensors to acquire high-quality data and device security. In this paper, UAV power line inspecting system is deferent from existing ones that used in Surveying and Mapping. According to characteristics of UAV for example equipped multiple sensor, side-looking imaging, working at low altitude, complex terrain conditions and corridor type flight, this paper puts forward a UAV power line inspecting scheme which comprehensively considered of the UAV performance, sensor parameters and task requirements. The scheme is finally tested in a region of Guangdong province, and the preliminary results show that the scheme is feasible

  3. New Method to Identify Field Joint Coating Failures Based on MFL In-Line Inspection Signals

    Directory of Open Access Journals (Sweden)

    Lianshuang Dai

    2018-02-01

    Full Text Available Above ground indirect detections and random excavations that have applied the past years for buried long distance oil and gas pipelines can only identify some damaged coating locations. Hence, large number of field joint coating (FJC failures happen unconsciously until they lead to failures of the pipelines. Based on the analysis of magnetic flux leakage (MFL in-line inspection (ILI signals, combined with the statistical results of 414 excavations from two different pipeline sections, a new method to identify the failed FJC is established. Though it can only identify FJC failures when there are signs of corrosion on pipe body, it is much more efficient and cost-saving. The concluded identification rule still needs more validations and improvements to be more applicable and accuracy.

  4. On-line monitoring and inservice inspection in codes; Betriebsueberwachung und wiederkehrende Pruefungen in den Regelwerken

    Energy Technology Data Exchange (ETDEWEB)

    Bartonicek, J.; Zaiss, W. [Gemeinschaftskernkraftwerk Neckar GmbH, Neckarwestheim (Germany); Bath, H.R. [Bundesamt fuer Strahlenschutz, Salzgitter (Germany). Geschaeftsstelle des Kerntechnischen Ausschusses (KTA)

    1999-08-01

    The relevant regulatory codes determine the ISI tasks and the time intervals for recurrent components testing for evaluation of operation-induced damaging or ageing in order to ensure component integrity on the basis of the last available quality data. In-service quality monitoring is carried out through on-line monitoring and recurrent testing. The requirements defined by the engineering codes elaborated by various institutions are comparable, with the KTA nuclear engineering and safety codes being the most complete provisions for quality evaluation and assurance after different, defined service periods. German conventional codes for assuring component integrity provide exclusively for recurrent inspection regimes (mainly pressure tests and optical testing). The requirements defined in the KTA codes however always demanded more specific inspections relying on recurrent testing as well as on-line monitoring. Foreign codes for ensuring component integrity concentrate on NDE tasks at regular time intervals, with time intervals scope of testing activities being defined on the basis of the ASME code, section XI. (orig./CB) [Deutsch] Fuer die Komponentenintegritaet sind die Schaedigungsmechanismen mit dem nach den Regelwerken einzuhaltenden Abstand abzusichern. Dabei ist die jeweils vorhandene (Ist-) Qualitaet als Ausgangspunkt entscheidend. Die Absicherung der vorhandenen Qualitaet im weiteren Betrieb erfolgt durch geeignete Betriebsueberwachung und wiederkehrende Pruefungen. Die Anforderungen der Regelwerke sind vergleichbar, wobei die Bestimmung der vorhandenen Qualitaet nach einer bestimmten Betriebszeit sowie deren Absicherung im weiteren Betrieb am vollstaendigsten auf Basis des KTA-Regelwerkes moeglich ist. Die Absicherung der Komponentenintegritaet im Betrieb beruht in deutschen konventionellen Regelwerken nur auf den wiederkehrenden Pruefungen (hauptsaechlich Druckpruefungen und Sichtpruefungen). Das KTA-Regelwerk forderte hier schon immer qualifizierte

  5. A review on pipeline corrosion, in-line inspection (ILI), and corrosion growth rate models

    International Nuclear Information System (INIS)

    Vanaei, H.R.; Eslami, A.; Egbewande, A.

    2017-01-01

    Pipelines are the very important energy transmission systems. Over time, pipelines can corrode. While corrosion could be detected by in-line inspection (ILI) tools, corrosion growth rate prediction in pipelines is usually done through corrosion rate models. For pipeline integrity management and planning selecting the proper corrosion ILI tool and also corrosion growth rate model is important and can lead to significant savings and safer pipe operation. In this paper common forms of pipeline corrosion, state of the art ILI tools, and also corrosion growth rate models are reviewed. The common forms of pipeline corrosion introduced in this paper are Uniform/General Corrosion, Pitting Corrosion, Cavitation and Erosion Corrosion, Stray Current Corrosion, Micro-Bacterial Influenced Corrosion (MIC). The ILI corrosion detection tools assessed in this study are Magnetic Flux Leakage (MFL), Circumferential MFL, Tri-axial MFL, and Ultrasonic Wall Measurement (UT). The corrosion growth rate models considered in this study are single-value corrosion rate model, linear corrosion growth rate model, non-linear corrosion growth rate model, Monte-Carlo method, Markov model, TD-GEVD, TI-GEVD model, Gamma Process, and BMWD model. Strengths and limitations of ILI detection tools, and also corrosion predictive models with some practical examples are discussed. This paper could be useful for those whom are supporting pipeline integrity management and planning. - Highlights: • Different forms of pipeline corrosion are explained. • Common In-Line Inspection (ILI) tools and corrosion growth rate models are introduced. • Strength and limitations of corrosion growth rate models/ILI tools are discussed. • For pipeline integrity management programs using more than one corrosion growth rate model/ILI tool is suggested.

  6. 7 CFR 58.52 - Time limit for packaging inspected or graded products with official identification.

    Science.gov (United States)

    2010-01-01

    ... Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946... Grading Services of Manufactured or Processed Dairy Products Marking, Branding, and Identifying Product...

  7. EVo: Net Shape RTM Production Line

    Directory of Open Access Journals (Sweden)

    Sven Torstrick

    2016-04-01

    Full Text Available EVo research platform is operated by the Center for Lightweight-Production-Technology of the German Aerospace Center in Stade. Its objective is technology demonstration of a fully automated RTM (Resin Transfer Molding production line for composite parts in large quantities. Process steps include cutting and ply handling, draping, stacking, hot-forming, preform-trimming to net shape, resin injection, curing and demolding.

  8. Intraprocedural dataflow analysis for software product lines

    DEFF Research Database (Denmark)

    Brabrand, Claus; Ribeiro, Márcio; Tolêdo, Társis

    2013-01-01

    Software product lines (SPLs) developed using annotative approaches such as conditional compilation come with an inherent risk of constructing erroneous products. For this reason, it is essential to be able to analyze such SPLs. However, as dataflow analysis techniques are not able to deal with SP...... and memory characteristics on five qualitatively different SPLs. On our benchmarks, the combined analysis strategy is up to almost eight times faster than the brute-force approach....

  9. Automated visual inspection of textile

    DEFF Research Database (Denmark)

    Jensen, Rune Fisker; Carstensen, Jens Michael

    1997-01-01

    A method for automated inspection of two types of textile is presented. The goal of the inspection is to determine defects in the textile. A prototype is constructed for simulating the textile production line. At the prototype the images of the textile are acquired by a high speed line scan camera...... the protype to a production line system we only need to gain a speed factor of 4....

  10. Design and application of radiation apparatus for sup 6 sup 0 Co cargo train on-line inspection system

    CERN Document Server

    Wu Zhi Fang; Zhang Yuai

    2002-01-01

    Based on the special requirement for radiation apparatus of sup 6 sup 0 Co cargo train on-line inspection system, a radiation apparatus including two-level shutter, working container, storing container and electromagnetism are designed. The makeup, working mode and functional realization of the radiation apparatus are introduced. The system is used in Manzhouli customs cargo train on-line inspection system. The practice shows that the radiation apparatus is reliable to work steadily and the operating speed of the main shutter can reach 0.1 s open and 0.15 s close

  11. Automating data analysis during the inspection of boiler tubes using line scanning thermography

    Science.gov (United States)

    Ley, Obdulia; Momeni, Sepand; Ostroff, Jason; Godinez, Valery

    2012-05-01

    Failures in boiler waterwalls can occur when a relatively small amount of corrosion and loss of metal have been experienced. This study presents our efforts towards the application of Line Scanning Thermography (LST) for the analysis of thinning in boiler waterwall tubing. LST utilizes a line heat source to thermally excite the surface to be inspected and an infrared detector to record the transient surface temperature increase observed due to the presence of voids, thinning or other defects. In waterwall boiler tubes the defects that can be detected using LST correspond to corrosion pitting, hydrogen damage and wall thinning produced by inadequate burner heating or problems with the water chemistry. In this paper we discuss how the LST technique is implemented to determine thickness from the surface temperature data, and we describe our efforts towards developing a semiautomatic analysis tool to speed up the time between scanning, reporting and implementing repairs. We compare the density of data produced by the common techniques used to assess wall thickness and the data produced by LST.

  12. 76 FR 24713 - Cooperative Inspection Programs: Interstate Shipment of Meat and Poultry Products

    Science.gov (United States)

    2011-05-02

    ... amenable species, such as processing game meat or for busy times in their retail shops around holidays. The... Service 9 CFR Parts 321, 332, and 381 Cooperative Inspection Programs: Interstate Shipment of Meat and... Shipment of Meat and Poultry Products AGENCY: Food Safety and Inspection Service, USDA. ACTION: Final rule...

  13. Resolving traceability issues of product derivation for software product lines

    OpenAIRE

    Abid, Saad bin

    2009-01-01

    peer-reviewed Dealing with traceability management issues during model based product derivation in large complex industrial SPL is error prone due to the lack of tool support. As a result traceability management between connected models emerges as an important research topic. In this position paper, we discuss research challenges as scenarios from developed example product line and give recommendations on resolving traceability issues during product derivation. We also discuss initial idea...

  14. Supporting Product Line Evolution with Framed Aspects

    DEFF Research Database (Denmark)

    Loughran, Neil; Rashid, Awais; Zhang, Weishan

    2004-01-01

    , but there will eventually come a time when a certain feature or scenario appears which could not have been foreseen in the early stages of development. We argue that frames and aspects when used in isolation cannot overcome these weaknesses effectively. However, they can be addressed by using the respective strengths......This paper discusses how evolution in software product lines can be supported using framed aspects: a combination of aspect-oriented programming and frame technology. Product line architectures and assets are subject to maintenance and evolution throughout their lifetime due to the emergence of new...... of both technologies in combination. The amalgamation of framing and aspect-oriented techniques can help in the integration of new features and thus reduce the risk of architectural erosion....

  15. Grain product of 34 soya mutant lines

    International Nuclear Information System (INIS)

    Salmeron E, J.; Mastache L, A. A.; Valencia E, F.; Diaz V, G. E.; Cervantes S, T.; De la Cruz T, E.; Garcia A, J. M.; Falcon B, T.; Gatica T, M. A.

    2009-01-01

    This work was development with the objective of obtaining information of the agronomic behavior of 34 soya mutant lines (R 4 M 18 ) for human consumption and this way to select the 2 better lines. The genetic materials were obtained starting from the variety ISAAEG-B M2 by means of the application of recurrent radiation with Co 60 gammas, to a dose of 350 Gray for the first two generations and both later to 200 Gray and selection during 17 cycles, being obtained the 34 better lines mutants with agronomic characteristic wanted and good flavor. The obtained results were that the mutant lines L 25 and L 32 produced the major quantity in branches/plant number with 7.5 and 7.25, pods/plant number with 171.25 and 167, grains/plant number with 350.89 and 333.07 and grain product (ton/ha) to 15% of humidity 5.15 and 4.68 ton/ha, respectively. (Author)

  16. Formulation of a Production Strategy for a Software Product Line

    Science.gov (United States)

    2009-08-01

    Strategy 9 5.1 Identifying the Critical Factors 9 5.1.1 Market Analysis 10 5.1.2 Building a Business Case 10 5.1.3 Scoping 10 5.1.4 Technology...ability to deliver new products quickly (i.e., its time to market ). The production strategy for a software product line is the high-level description of... strategy . The critical factors mentioned above refer to both market conditions that affect an organ- ization and how an organization’s products can

  17. Product Line Enabled Intelligent Mobile Middleware

    DEFF Research Database (Denmark)

    Zhang, Weishan; Kunz, Thomas; Hansen, Klaus Marius

    2007-01-01

    research project called PLIMM that focuses on user-centered application scenarios. PLIMM is designed based on software product line ideas which make it possible for specialized customization and optimization for different purposes and hardware/software platforms. To enable intelligence, the middleware...... needs access to a range of context models. We model these contexts with OWL, focusing on user-centered concepts. The basic building block of PLIMM is the enhanced BDI agent where OWL context ontology logic reasoning will add indirect beliefs to the belief sets. Our approach also addresses the handling...

  18. Applications of the energy differentiation type radiation line sensor to such as inspection for the plumbing corrosion

    International Nuclear Information System (INIS)

    Tomita, Yasuhiro; Shirayanagi, Yuji; Matsui, Shinjiro; Kamiya, Yosuke; Kobayashi, Akira

    2015-01-01

    The authors have engaged in development of the next-generation radiation detectors that can give information on energy such as X-rays and γ-rays, and commercialized an energy discrimination type radiation line sensor capable of discriminating the energy of photons using a CdTe radiation detector element. This paper introduces the structure and principles of this energy discrimination type radiation line sensor. As the basic application, it also introduces the material identification, energy discrimination type X-ray CT imaging, and the quantitative determination of iron plate thickness using X-ray. In addition, it introduces the radiation line sensor we have developed for inspecting the reduced amount of wall thickness of piping with insulation materials. This radiation line sensor for pipe thinning inspection combined with radiation sources (X-rays, γ-rays) and a transport system is capable of accurately and efficiently inspecting reduced wall thickness, while moving the censor on the covered pipe with heat insulating materials through remote control, without removing piping insulation materials and without stopping the use of piping. (A.O.)

  19. 9 CFR 327.25 - Disposition procedures for product condemned or ordered destroyed under import inspection.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Disposition procedures for product... § 327.25 Disposition procedures for product condemned or ordered destroyed under import inspection. (a... coloring, 40 parts water, 40 parts liquid detergent, and 40 parts oil of citronella, or other proprietary...

  20. Inspection Database

    Data.gov (United States)

    U.S. Department of Health & Human Services — FDA is disclosing the final inspection classification for inspections related to currently marketed FDA-regulated products. The disclosure of this information is not...

  1. Simulation Study of a Vehicle Production Line for Productivity Improvement

    Directory of Open Access Journals (Sweden)

    M.F.F. Ab Rashid

    2015-06-01

    Full Text Available This paper presents the study of a motorcycle frame production line in a particular company in Malaysia. Due to the high demand, the company needs to increase its production by at least 12% compared with current output. In order to improve productivity, the production-floor data was collected and simulated using the discrete event simulation approach. Later, a number of suggestions for improvement were simulated to identify the effect of the suggestions on productivity. In addition, cost analysis was also undertaken to identify the profit margin for a particular period of time for each suggestion. Simulation results indicate that there are three suggestions that are able to fulfill the 12% volume increment. In the short term, the suggestion to hire an assistant line leader will give instant effect to the profit. Meanwhile, for the medium term, Poka-yoke will give higher profit compared with the others, while in the long term, SOP (standard operating procedure implementation will yield a better profit margin. In future, the simulation of a dynamic demand model for this product is suggested to cope with new trends in the market.

  2. The Structured Intuitive Model for Product Line Economics (SIMPLE)

    National Research Council Canada - National Science Library

    Clements, Paul C; McGregor, John D; Cohen, Sholom G

    2005-01-01

    .... This report presents the Structured Intuitive Model of Product Line Economics (SIMPLE), a general-purpose business model that supports the estimation of the costs and benefits in a product line development organization...

  3. Change impact analysis for software product lines

    Directory of Open Access Journals (Sweden)

    Jihen Maâzoun

    2016-10-01

    Full Text Available A software product line (SPL represents a family of products in a given application domain. Each SPL is constructed to provide for the derivation of new products by covering a wide range of features in its domain. Nevertheless, over time, some domain features may become obsolete with the apparition of new features while others may become refined. Accordingly, the SPL must be maintained to account for the domain evolution. Such evolution requires a means for managing the impact of changes on the SPL models, including the feature model and design. This paper presents an automated method that analyzes feature model evolution, traces their impact on the SPL design, and offers a set of recommendations to ensure the consistency of both models. The proposed method defines a set of new metrics adapted to SPL evolution to identify the effort needed to maintain the SPL models consistently and with a quality as good as the original models. The method and its tool are illustrated through an example of an SPL in the Text Editing domain. In addition, they are experimentally evaluated in terms of both the quality of the maintained SPL models and the precision of the impact change management.

  4. 46 CFR 159.007-11 - Production inspections and tests: Yearly report.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Production inspections and tests: Yearly report. 159.007-11 Section 159.007-11 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL APPROVAL OF EQUIPMENT AND MATERIALS Production...

  5. A study of the long-range inspection method for on-line monitoring of pipes in nuclear power plants

    International Nuclear Information System (INIS)

    Eom, Heung Seop; Lim, Sa Hoe; Kim, Jae Hee; Kim, Young H.; Song, Sung Jin

    2005-01-01

    Deployment of an advanced on-line monitoring of the component integrity offers the prospect of an improved performance, enhanced safety, and reduced overall cost for nuclear power plants (NPPs). Also ultrasonic guided ultrasonic wave has been known as one of the promising techniques that could be utilized for on-line monitoring, because it enables us to undertake a long-range inspection of structures such as plates and pipes. The present work is aimed at developing a new method using ultrasonic guided waves for the on-line monitoring of pipes. For this purpose we fabricated the necessary hardware and carried out transmitter tuning, group velocity measurement, receiver tuning, and mode identification. Finally we carried out an experiment on a long-range inspection with the developed hardware and the techniques. In the experiment, we could detect the flaws at a distance of about 20M from the transmitter, and we could verify the possibility of using the developed hardware and techniques for on-line monitoring of pipes in NPPs

  6. A state indicator on regional scale for high-voltage power lines: Defining a priority for in situ inspections

    International Nuclear Information System (INIS)

    Comelli, M.; Colonna, N.; Martini, L.; Licitra, G.

    2009-01-01

    An integrated system to evaluate the magnetic field generated by power lines exposure has been developed using a specific simulation model (PLEIA-EMF). This is part of a software tool-set, subjected to internal suitability verifications and in-field validations. A state indicator related to each span has been determined using the data extracted from digital cartography, the magnetic field calculated by PLEIA and the number of people living in the nearest buildings. In this way, it is possible to determine eventual criticalities in the considered area, focusing attention on those cases with more considerable exposure levels and involving a higher number of people. A campaign of inspections has been planned using PLEIA simulations. The reliability of stored technical data and the real population exposure levels have been evaluated in critical cases, individuated through the following described methodology. The procedures leading to the indicator determination and the modalities of in situ inspections are here presented. (authors)

  7. A Software Product Line Vision for Defense Acquisition

    National Research Council Canada - National Science Library

    Campbell, Grady

    2002-01-01

    Experience in industry and government over the last 10 years has shown that a software product line approach can significantly improve productivity and product quality, facilitate change, and reduce life-cycle costs...

  8. 46 CFR 164.023-13 - Production tests and inspections.

    Science.gov (United States)

    2010-10-01

    ... Constant Rate of Traverse tensile testing machine, capable of initial clamp separation of ten inches and a... production testing on a lot must meet the following criteria for the lot to be shipped as Coast Guard... the acceptance testing values but not less than the performance minimums. (2) Length/weight values...

  9. Mechanical Implementation and Simulation of MoboLab, A Mobile Robot for Inspection of Power Transmission Lines

    Directory of Open Access Journals (Sweden)

    Mahmud Saadat Foumani

    2008-11-01

    Full Text Available This paper describes the first phase in development of a mobile robot that can navigate aerial power transmission lines completely unattended by human operator. Its ultimate purpose is to automate inspection of power transmission lines and their equipments. The authors have developed a scaled functional model of such a mobile robot with a preliminary simple computer based on-off controller. MoboLab (Mobile Laboratory navigates a power transmission line between two strain towers. It can maneuver over obstructions created by line equipments such as insulators, warning spheres, dampers, and spacer dampers. It can also easily negotiate the towers by its three flexible arms. MoboLab has an internal main screw which enables the robot to move itself or its two front and rear arms independently through changing gripped points. When the front arm gets close to an obstacle, the arm detaches from the line and goes down, the robot moves forward, the arm passes the obstacle and grippes the line again. In a same way another arms pass the obstacle.

  10. Capacity building improve Malaysia's inspection and monitoring system for aquaculture and fishery products

    NARCIS (Netherlands)

    Gevers, G.J.M.; Zoontjes, P.W.; Essers, M.L.; Klijnstra, M.; Gerssen, A.

    2012-01-01

    The project aimed to help build a credible inspection and monitoring system that can guarantee safe quality products of Ministry of Health (MoH) and Department of Fisheries (DoF) by upgrading the analytical capacity of the laboratory staff directly involved in the analysis and detection of forbidden

  11. Harnessing natural product assembly lines: structure, promiscuity, and engineering.

    Science.gov (United States)

    Ladner, Christopher C; Williams, Gavin J

    2016-03-01

    Many therapeutically relevant natural products are biosynthesized by the action of giant mega-enzyme assembly lines. By leveraging the specificity, promiscuity, and modularity of assembly lines, a variety of strategies has been developed that enables the biosynthesis of modified natural products. This review briefly summarizes recent structural advances related to natural product assembly lines, discusses chemical approaches to probing assembly line structures in the absence of traditional biophysical data, and surveys efforts that harness the inherent or engineered promiscuity of assembly lines for the synthesis of non-natural polyketides and non-ribosomal peptide analogues.

  12. Simulation Based Optimization for World Line Card Production System

    Directory of Open Access Journals (Sweden)

    Sinan APAK

    2012-07-01

    Full Text Available Simulation based decision support system is one of the commonly used tool to examine complex production systems. The simulation approach provides process modules which can be adjusted with certain parameters by using data relatively easily obtainable in production process. World Line Card production system simulation is developed to evaluate the optimality of existing production line via using discrete event simulation model with variaty of alternative proposals. The current production system is analysed by a simulation model emphasizing the bottlenecks and the poorly utilized production line. Our analysis identified some improvements and efficient solutions for the existing system.

  13. Using radio frequency and ultrasonic antennas for inspecting pin-type insulators on medium-voltage overhead distribution lines

    Directory of Open Access Journals (Sweden)

    Cícero Lefort Borges

    2013-05-01

    Full Text Available This paper summarises the activities undertaken when using antennas (ultrasound and radiofrequency for identifying insulators in pre-failure state by detecting the noise emitted by the distribution line and correlating this with these insulators (porcelain pin type dielectric breakdown. This has led to developing low-cost maintenance procedures and providing support and criteria for engineer-ing decisions regarding replacing these insulators. The technique used two detectors; a radio frequency detector was used in a first investigation of a particular distribution line, set to 40 MHz and installed on the roof of a moving vehicle. The ultrasound detector was used for inspecting (phases A, B, C each structure (pole selected. Atmospheric conditions had no influence on defining pre-failure insulators (pin type based on the noise detection technique. Pin type insulators emitting noise should be replaced since measurement was made from the ground and near the base of the post.

  14. Inspection vehicle

    International Nuclear Information System (INIS)

    Takahashi, Masaki; Omote, Tatsuyuki; Yoneya, Yutaka; Tanaka, Keiji; Waki, Tetsuro; Yoshida, Tomiji; Kido, Tsuyoshi.

    1993-01-01

    An inspection vehicle comprises a small-sized battery directly connected with a power motor or a direct power source from trolly lines and a switching circuit operated by external signals. The switch judges advance or retreat by two kinds of signals and the inspection vehicle is recovered by self-running. In order to recover the abnormally stopped inspection vehicle to the targeted place, the inspection vehicle is made in a free-running state by using a clutch mechanism and is pushed by an other vehicle. (T.M.)

  15. A Fast Inspection of Tool Electrode and Drilling Depth in EDM Drilling by Detection Line Algorithm.

    Science.gov (United States)

    Huang, Kuo-Yi

    2008-08-21

    The purpose of this study was to develop a novel measurement method using a machine vision system. Besides using image processing techniques, the proposed system employs a detection line algorithm that detects the tool electrode length and drilling depth of a workpiece accurately and effectively. Different boundaries of areas on the tool electrode are defined: a baseline between base and normal areas, a ND-line between normal and drilling areas (accumulating carbon area), and a DD-line between drilling area and dielectric fluid droplet on the electrode tip. Accordingly, image processing techniques are employed to extract a tool electrode image, and the centroid, eigenvector, and principle axis of the tool electrode are determined. The developed detection line algorithm (DLA) is then used to detect the baseline, ND-line, and DD-line along the direction of the principle axis. Finally, the tool electrode length and drilling depth of the workpiece are estimated via detected baseline, ND-line, and DD-line. Experimental results show good accuracy and efficiency in estimation of the tool electrode length and drilling depth under different conditions. Hence, this research may provide a reference for industrial application in EDM drilling measurement.

  16. Portfolio analysis of a destination's tourism "product line"

    Science.gov (United States)

    Harold Daniel

    2007-01-01

    If we think of a tourist destination as a platform from which a variety of tourist experiences can be delivered, we could conceptualize these experiences as the "product line" offered by or associated with the tourist destination. That conceptualization enables the manager of the destination to employ the logic and discipline associated with product line...

  17. Technology Management within Product Lines in High Technology Markets

    Science.gov (United States)

    Sarangee, Kumar R.

    2009-01-01

    Understanding the nuances of product line management has been of great interest to business scholars and practitioners. This assumes greater significance for firms conducting business in technologically dynamic industries, where they face certain challenges regarding the management of multiple, overlapping technologies within their product lines.…

  18. Bucket Brigades to Increase Productivity in a Luxury Assembly Line

    OpenAIRE

    Carlo, Filippo De; Borgia, Orlando; Tucci, Mario

    2013-01-01

    One of the most challenging issues in manual assembly lines is to achieve the best balance of workloads. There are many analytic approaches to solve this problem, but they are often neglected, since they are time-consuming and require high level engineering skills. Fashion bags packaging lines must comply with a number of different products with low production volumes, while the organization of the line is often under the mere responsibility of the foreman, who balances workloads in an empiri...

  19. Machine vision system: a tool for quality inspection of food and agricultural products.

    Science.gov (United States)

    Patel, Krishna Kumar; Kar, A; Jha, S N; Khan, M A

    2012-04-01

    Quality inspection of food and agricultural produce are difficult and labor intensive. Simultaneously, with increased expectations for food products of high quality and safety standards, the need for accurate, fast and objective quality determination of these characteristics in food products continues to grow. However, these operations generally in India are manual which is costly as well as unreliable because human decision in identifying quality factors such as appearance, flavor, nutrient, texture, etc., is inconsistent, subjective and slow. Machine vision provides one alternative for an automated, non-destructive and cost-effective technique to accomplish these requirements. This inspection approach based on image analysis and processing has found a variety of different applications in the food industry. Considerable research has highlighted its potential for the inspection and grading of fruits and vegetables, grain quality and characteristic examination and quality evaluation of other food products like bakery products, pizza, cheese, and noodles etc. The objective of this paper is to provide in depth introduction of machine vision system, its components and recent work reported on food and agricultural produce.

  20. State of technology, system and solution supporting on-line maintenance - company's activities and products

    International Nuclear Information System (INIS)

    Nishitani, Junichi; Shimizu, Shunichi; Higasa, Hisakazu

    2010-01-01

    The new inspection system based on operator's maintenance and monitoring program of nuclear power plants was introduced in Japan more than one year ago and recommended on-line maintenance (maintenance during operation) will be carried out to increase capacity factor with safe and reliable operation of the plant. In this feature article, nine experts described the state of technology, system and solution supporting on-line maintenance - company's activities and products. These were titled as 'MHI's technology supporting on-line maintenance'. 'Technology supporting on-line maintenance - Toshiba's activities to upgrade monitoring and diagnostic service and maintenance management', 'AsahiKASEI's activities of on-line maintenance', 'Importance of information sharing of on-line maintenance and its ideal method-function of impact plan of IBM Maximo Asset Management for Nuclear', 'US's on-line maintenance and information systems', 'SmartProcedures realizing safe operation of nuclear power plant - proposal of computerized procedures', 'Ultrasonic leak detection system SDT170', 'Application of infrared thermography for equipment maintenance in nuclear power plant' and 'On-line condition monitoring system - condition eye'. (T. Tanaka)

  1. No effects of power line frequency extremely low frequency electromagnetic field exposure on selected neurobehavior tests of workers inspecting transformers and distribution line stations versus controls.

    Science.gov (United States)

    Li, Li; Xiong, De-fu; Liu, Jia-wen; Li, Zi-xin; Zeng, Guang-cheng; Li, Hua-liang

    2014-03-01

    We aimed to evaluate the interference of 50 Hz extremely low frequency electromagnetic field (ELF-EMF) occupational exposure on the neurobehavior tests of workers performing tour-inspection close to transformers and distribution power lines. Occupational short-term "spot" measurements were carried out. 310 inspection workers and 300 logistics staff were selected as exposure and control. The neurobehavior tests were performed through computer-based neurobehavior evaluation system, including mental arithmetic, curve coincide, simple visual reaction time, visual retention, auditory digit span and pursuit aiming. In 500 kV areas electric field intensity at 71.98% of total measured 590 spots were above 5 kV/m (national occupational standard), while in 220 kV areas electric field intensity at 15.69% of total 701 spots were above 5 kV/m. Magnetic field flux density at all the spots was below 1,000 μT (ICNIRP occupational standard). The neurobehavior score changes showed no statistical significance. Results of neurobehavior tests among different age, seniority groups showed no significant changes. Neurobehavior changes caused by daily repeated ELF-EMF exposure were not observed in the current study.

  2. Effect of failures and repairs on multiple cell production lines

    Energy Technology Data Exchange (ETDEWEB)

    Legato, P.; Bobbio, A.; Roberti, L.

    1989-01-01

    This paper examines a production line composed of multiple stages, or cells, which are passed in sequential order to arrive to the final product. Two possible coordination disciplines are considered, namely: the classical tandem arrangement of sequential working centers with input buffer and the kanban scheme, considered the Japanese shop floor realization of the Just-In-Time (JIT) manifacturing approach. The production line is modelled and analysed by means of Stochastic Petri Nets (SPN). Finally an analysis is made of the possibility that the working cells can incur failure/repair cycles perturbing the production flow of the line and thus reduce performance indices.

  3. Designing a two-rank acceptance sampling plan for quality inspection of geospatial data products

    Science.gov (United States)

    Tong, Xiaohua; Wang, Zhenhua; Xie, Huan; Liang, Dan; Jiang, Zuoqin; Li, Jinchao; Li, Jun

    2011-10-01

    To address the disadvantages of classical sampling plans designed for traditional industrial products, we originally propose a two-rank acceptance sampling plan (TRASP) for the inspection of geospatial data outputs based on the acceptance quality level (AQL). The first rank sampling plan is to inspect the lot consisting of map sheets, and the second is to inspect the lot consisting of features in an individual map sheet. The TRASP design is formulated as an optimization problem with respect to sample size and acceptance number, which covers two lot size cases. The first case is for a small lot size with nonconformities being modeled by a hypergeometric distribution function, and the second is for a larger lot size with nonconformities being modeled by a Poisson distribution function. The proposed TRASP is illustrated through two empirical case studies. Our analysis demonstrates that: (1) the proposed TRASP provides a general approach for quality inspection of geospatial data outputs consisting of non-uniform items and (2) the proposed acceptance sampling plan based on TRASP performs better than other classical sampling plans. It overcomes the drawbacks of percent sampling, i.e., "strictness for large lot size, toleration for small lot size," and those of a national standard used specifically for industrial outputs, i.e., "lots with different sizes corresponding to the same sampling plan."

  4. Innovative automation solutions applied to nuclear fuel production and inspection processes

    International Nuclear Information System (INIS)

    Vas, Ananth

    2012-01-01

    The nuclear industry in India is slated for fast paced growth in the coming years, with a great focus on increasing the capacity for producing, inspecting and finally reprocessing of nuclear fuel. Modern techniques of industrial automation such as robotics, machine vision and laser based systems have been deployed extensively to improve the productivity and output of existing and future installations, particularly for the fuel handling stages mentioned

  5. Preparing for Automated Derivation of Products in a Software Product Line

    National Research Council Canada - National Science Library

    McGregor, John D

    2005-01-01

    ... to bring a product to market, or through other production improvements. Business goals such as these make automated product derivation an appealing strategy to a software product line organization...

  6. Inspection method for solidification product of radioactive waste and method of preparing solidification product of radiation waste

    International Nuclear Information System (INIS)

    Izumida, Tatsuo; Tamada, Shin; Matsuda, Masami; Kamata, Shoji; Kikuchi, Makoto.

    1993-01-01

    A powerful X-ray generation device using an electron-ray accelerator is used for inspecting presence or absence of inner voids in solidification products of radioactive wastes during or after solidification. By installing the X-ray CT system and the radioactive waste solidifying facility together, CT imaging for solidification products is conducted in a not-yet cured state of solidifying materials during or just after the injection. If a defect that deteriorates the durability of the solidification products should be detected, the solidification products are repaired, for example, by applying vibrations to the not-yet cured solidification products. Thus, since voids or cracks in the radioactive wastes solidification products, which were difficult to be measured so far, can be measured in a short period of time accurately thereby enabling to judge adaptability to the disposal standards, inspection cost for the radioactive waste solidification product can be saved remarkably. Further, the inside of the radioactive waste solidification products can be evaluated correctly and visually, so that safety in the ground disposal storage of the radioactive solidification products can be improved remarkably. (N.H.)

  7. Synergy between Software Product Line and Intelligent Mobile Middleware

    DEFF Research Database (Denmark)

    Zhang, Weishan; Hansen, Klaus Marius

    2007-01-01

    with OWL ontology reasoning enhanced BDI (belief-desire-intention) agents in an ongoing research project called PLIMM (product line enabled intelligent mobile middleware), in which Frame based software product line techniques are applied. Besides the advantages of a software product line, our approach can...... handle ontology evolution and keep all related assets in a consistent state. Ontology evolution is a problem that has not been addressed by current mobile middleware. Another advantage is the ability to configure Jadex BDI agents for different purpose and enhance agent intelligence by adding logic...

  8. EXERGY ANALYSIS OF PRODUCTION LINE CANDIED FRUIT

    Directory of Open Access Journals (Sweden)

    V. D. Dem'шanov

    2014-01-01

    Full Text Available Summary. The task of exergy analysis - evaluation based on the second law of thermodynamics, thermodynamic degree of technical perfection of the whole system, as well as to identify those stages of a technical process, which contains the bulk of the loss of exergy in order to improve its efficiency. Using exergy analysis allows to solve a wide range of technical problems on the basis of a unified thermodynamic methods. Exergy analysis was performed by the method whereby thermotechnological system candied fruit production, conventionally separated from the environment of the closed control surface. Exchange scheme under consideration thermotechnological candied fruit production material, thermal and energy flows to the environment, as well as between the control surfaces. Exergy in external input material streams: air and water and citric acid, as well as output streams without having increment Shih-exergy in the process of passing through the reference surface - of running air-water and after washing, are in thermodynamic equilibrium with the surroundings is zero. In the total number of internal exergy losses include losses from the final result of the temperature difference in the heat exchange between the raw material to be dried and heated air electromechanical arising from irreversible alteration of structural and mechanical properties of the product, and the hydraulic loss due to the sudden increase of the specific volume of air as it enters the working chamber dryer. The resulting exergy efficiency is 8.87 %, which is 3.7 % higher than when using the technology of the prototype based on solar air-dried product. This indicates an increase in the degree of perfection of the thermodynamic system by using microwave heating of the product in combination with the removal of moisture in the atmosphere low temperature coolant, which precludes significant outside exergy loss on drying step.

  9. Lean buffering in serial production lines with Bernoulli machines

    Directory of Open Access Journals (Sweden)

    A. B. Hu

    2006-01-01

    Full Text Available Lean buffering is the smallest buffer capacity necessary to ensure the desired production rate of a manufacturing system. In this paper, analytical methods for selecting lean buffering in serial production lines are developed under the assumption that the machines obey the Bernoulli reliability model. Both closed-form expressions and recursive approaches are investigated. The cases of identical and nonidentical machines are analyzed. Results obtained can be useful for production line designers and production managers to maintain the required production rate with the smallest possible inventories.

  10. In-Line Inspection of Additive Manufactured Parts Using Laser Ultrasonics, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Additive manufacturing (AM) is an increasingly popular technique for rapid, low-cost production of parts directly from a CAD file. AM is especially appealing for...

  11. Share-of-Surplus Product Line Optimisation with Price Levels

    Directory of Open Access Journals (Sweden)

    X. G. Luo

    2014-01-01

    Full Text Available Kraus and Yano (2003 established the share-of-surplus product line optimisation model and developed a heuristic procedure for this nonlinear mixed-integer optimisation model. In their model, price of a product is defined as a continuous decision variable. However, because product line optimisation is a planning process in the early stage of product development, pricing decisions usually are not very precise. In this research, a nonlinear integer programming share-of-surplus product line optimization model that allows the selection of candidate price levels for products is established. The model is further transformed into an equivalent linear mixed-integer optimisation model by applying linearisation techniques. Experimental results in different market scenarios show that the computation time of the transformed model is much less than that of the original model.

  12. Security Requirements Management in Software Product Line Engineering

    Science.gov (United States)

    Mellado, Daniel; Fernández-Medina, Eduardo; Piattini, Mario

    Security requirements engineering is both a central task and a critical success factor in product line development due to the complexity and extensive nature of product lines. However, most of the current product line practices in requirements engineering do not adequately address security requirements engineering. Therefore, in this chapter we will propose a security requirements engineering process (SREPPLine) driven by security standards and based on a security requirements decision model along with a security variability model to manage the variability of the artefacts related to security requirements. The aim of this approach is to deal with security requirements from the early stages of the product line development in a systematic way, in order to facilitate conformance with the most relevant security standards with regard to the management of security requirements, such as ISO/IEC 27001 and ISO/IEC 15408.

  13. Production inventory policies for defective items with inspection errors, sales return, imperfect rework process and backorders

    Science.gov (United States)

    Jaggi, Chandra K.; Khanna, Aditi; Kishore, Aakanksha

    2016-03-01

    In order to sustain the challenges of maintaining good quality and perfect screening process, rework process becomes a rescue to compensate for the imperfections present in the production system. The proposed model attempts to explore the existing real-life situation with a more practical approach by incorporating the concept of imperfect rework as this occurs as an unavoidable problem to the firm due to irreparable disorders even in the reworked items. Hence, a production inventory model is formulated here to study the combined effect of imperfect quality items, faulty inspection process and imperfect rework process on the optimal production quantity and optimal backorder level. An analytical method is employed to maximize the expected total profit per unit time. Moreover, the results of several previous research articles namely Chiu et al (2006), Chiu et al (2005), Salameh and Hayek (2001), and classical EPQ with shortages are deduced as special cases. To demonstrate the applicability of the model, and to observe the effects of key parameters on the optimal replenishment policy, a numerical example along with a comprehensive sensitivity analysis has been presented. The pertinence of the model can be found in most of the manufacturing industries like textile, electronics, furniture, footwear, plastics etc. A production lot size model has been explored for defectives items with inspection errors and an imperfect rework process.

  14. General description and production lines of the Egyptian fuel manufacturing pilot plant

    International Nuclear Information System (INIS)

    Zidan, W.I.; Elseaidy, I.M.

    1999-01-01

    The Egyptian Fuel Manufacturing Pilot Plant, FMPP, is a new facility, producing an MTR-type fuel elements required for the Egyptian Second Research Reactor, ETRR-2, as well as other plates or elements for an external clients with the same type and enrichment percent or lower, (LEU). General description is presented. The production lines in FMPP, which begin from uranium hexaflouride (UF 6 , 19.7±0.2 % U 235 by wt), aluminum powder, and nuclear grade 6061 aluminium alloy in sheets, bars, and rods with the different heat treatments and dimensions as a raw materials, are processed through a series of the manufacturing, inspection, and quality control plan to produce the final specified MTR-type fuel elements. All these processes and the product control in each step are presented. The specifications of the final product are presented. (author)

  15. Customized Pull Systems for Single-Product Flow Lines

    NARCIS (Netherlands)

    Gaury, E.G.A.; Kleijnen, J.P.C.; Pierreval, H.

    1998-01-01

    Traditionally pull production systems are managed through classic control systems such as Kanban, Conwip, or Base stock, but this paper proposes ‘customized’ pull control. Customization means that a given production line is managed through a pull control system that in principle connects each stage

  16. Ultrasonic inspection

    International Nuclear Information System (INIS)

    Satittada, Gannaga

    1984-01-01

    Ultrasonic inspection is one of the most widely used methods for nondestructive inspection. The beam of high-frequency sound wave, ultrasonic wave, is introduced into the material. It travels through the material with some attendant loss of energy and can be reflected at interfaces. The reflected beam is detected and analyzed. Ultrasonic inspection is used to detect flaws in metal parts as well as in welded, brazed and bonded joints during research work and developing production and service. It is also used to detect and locate porosity, pipe, and flakes. In addition, it can be used for the measurement of metal thickness. Ultrasonic inspection is therefore used for quality control and material inspection in all major industries

  17. Recombinant protein production from stable mammalian cell lines and pools.

    Science.gov (United States)

    Hacker, David L; Balasubramanian, Sowmya

    2016-06-01

    We highlight recent developments for the production of recombinant proteins from suspension-adapted mammalian cell lines. We discuss the generation of stable cell lines using transposons and lentivirus vectors (non-targeted transgene integration) and site-specific recombinases (targeted transgene integration). Each of these methods results in the generation of cell lines with protein yields that are generally superior to those achievable through classical plasmid transfection that depends on the integration of the transfected DNA by non-homologous DNA end-joining. This is the main reason why these techniques can also be used for the generation of stable cell pools, heterogenous populations of recombinant cells generated by gene delivery and genetic selection without resorting to single cell cloning. This allows the time line from gene transfer to protein production to be reduced. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. THE LINE FOR PRODUCTION OF DRIED APPLES, PEARS, CARROTS, PUMPKIN AND CHIPS

    Directory of Open Access Journals (Sweden)

    G. V. Kalashnikov

    2015-01-01

    Full Text Available The line is intended for processing of fruit and vegetable raw materials and receiving dried apples, pears, carrots, pumpkins and the fruit-and-vegetable of chips. The line solves problems of improvement of quality of a ready-made product and thermal production efficiency due to more rational alternation of the technological modes of a moisture increment and dehumidification with high extent of use of an energy potential of the heat carrier, use of the inert heat carrier (steam identical by the form for technological thermal processes, decrease in specific energy consumption and metal consumption, and also an intensification of moisture evaporation and creation of the compact multipurpose technological line for production of fruit and vegetable products with the expanded range. The technological production line of dried apples, pears, carrots, pumpkin and fruit and vegetable chips contains the jet washer, the inspection conveyor, the size grader, the car for removal of a seed nest and the device are sharp fruits and vegetables on plates, the sulfiter, the dryer and the packing automatic packing machine. Thus the line contains the combined toroidal device for heatmoisture of handling continuous action divided into sections: section of heating of raw materials, section of convective drying, section of preliminary hydration, which is located between microwave drying sections, and the section of cooling of the dried-up product intended for bringing a product to final readiness. The equipment complex from the drum car with the washing block and multipurpose installation with crushing of raw materials and office of sunflower seeds taking into account raw materials type is provided in lines. Are used recirculation a contour, the heating of the initial raw material fulfilled after drying of pairs and a condensate in the closed contour for creation energy-saving of the "know-how" of a ready product. The line represents modular blocks and is recustomized

  19. Product Lines for Service Oriented Applications - PL for SOA

    Directory of Open Access Journals (Sweden)

    Maurice H. ter Beek

    2011-08-01

    Full Text Available PL for SOA proposes, formally, a software engineering methodology, development techniques and support tools for the provision of service product lines. We propose rigorous modeling techniques for the specification and verification of formal notations and languages for service computing with inclinations of variability. Through these cutting-edge technologies, increased levels of flexibility and adaptivity can be achieved. This will involve developing semantics of variability over behavioural models of services. Such tools will assist organizations to plan, optimize and control the quality of software service provision, both at design and at run time by making it possible to develop flexible and cost-effective software systems that support high levels of reuse. We tackle this challenge from two levels. We use feature modeling from product line engineering and, from a services point of view, the orchestration language Orc. We introduce the Smart Grid as the service product line to apply the techniques to.

  20. Optimization and Improvement of Test Processes on a Production Line

    Science.gov (United States)

    Sujová, Erika; Čierna, Helena

    2018-06-01

    The paper deals with increasing processes efficiency at a production line of cylinder heads of engines in a production company operating in the automotive industry. The goal is to achieve improvement and optimization of test processes on a production line. It analyzes options for improving capacity, availability and productivity of processes of an output test by using modern technology available on the market. We have focused on analysis of operation times before and after optimization of test processes at specific production sections. By analyzing measured results we have determined differences in time before and after improvement of the process. We have determined a coefficient of efficiency OEE and by comparing outputs we have confirmed real improvement of the process of the output test of cylinder heads.

  1. Development and Application of the Key Technologies for the Quality Control and Inspection of National Geographical Conditions Survey Products

    Science.gov (United States)

    Zhao, Y.; Zhang, L.; Ma, W.; Zhang, P.; Zhao, T.

    2018-04-01

    The First National Geographical Condition Survey is a predecessor task to dynamically master basic situations of the nature, ecology and human activities on the earth's surface and it is the brand-new mapping geographic information engineering. In order to ensure comprehensive, real and accurate survey results and achieve the quality management target which the qualified rate is 100 % and the yield is more than 80 %, it is necessary to carry out the quality control and result inspection for national geographical conditions survey on a national scale. To ensure that achievement quality meets quality target requirements, this paper develops the key technology method of "five-in-one" quality control that is constituted by "quality control system of national geographical condition survey, quality inspection technology system, quality evaluation system, quality inspection information management system and national linked quality control institutions" by aiming at large scale, wide coverage range, more undertaking units, more management levels, technical updating, more production process and obvious regional differences in the national geographical condition survey and combining with novel achievement manifestation, complicated dependency, more special reference data, and large data size. This project fully considering the domestic and foreign related research results and production practice experience, combined with the technology development and the needs of the production, it stipulates the inspection methods and technical requirements of each stage in the quality inspection of the geographical condition survey results, and extends the traditional inspection and acceptance technology, and solves the key technologies that are badly needed in the first national geographic survey.

  2. Visual Perception-Based Statistical Modeling of Complex Grain Image for Product Quality Monitoring and Supervision on Assembly Production Line.

    Directory of Open Access Journals (Sweden)

    Jinping Liu

    Full Text Available Computer vision as a fast, low-cost, noncontact, and online monitoring technology has been an important tool to inspect product quality, particularly on a large-scale assembly production line. However, the current industrial vision system is far from satisfactory in the intelligent perception of complex grain images, comprising a large number of local homogeneous fragmentations or patches without distinct foreground and background. We attempt to solve this problem based on the statistical modeling of spatial structures of grain images. We present a physical explanation in advance to indicate that the spatial structures of the complex grain images are subject to a representative Weibull distribution according to the theory of sequential fragmentation, which is well known in the continued comminution of ore grinding. To delineate the spatial structure of the grain image, we present a method of multiscale and omnidirectional Gaussian derivative filtering. Then, a product quality classifier based on sparse multikernel-least squares support vector machine is proposed to solve the low-confidence classification problem of imbalanced data distribution. The proposed method is applied on the assembly line of a food-processing enterprise to classify (or identify automatically the production quality of rice. The experiments on the real application case, compared with the commonly used methods, illustrate the validity of our method.

  3. Visual Perception-Based Statistical Modeling of Complex Grain Image for Product Quality Monitoring and Supervision on Assembly Production Line.

    Science.gov (United States)

    Liu, Jinping; Tang, Zhaohui; Zhang, Jin; Chen, Qing; Xu, Pengfei; Liu, Wenzhong

    2016-01-01

    Computer vision as a fast, low-cost, noncontact, and online monitoring technology has been an important tool to inspect product quality, particularly on a large-scale assembly production line. However, the current industrial vision system is far from satisfactory in the intelligent perception of complex grain images, comprising a large number of local homogeneous fragmentations or patches without distinct foreground and background. We attempt to solve this problem based on the statistical modeling of spatial structures of grain images. We present a physical explanation in advance to indicate that the spatial structures of the complex grain images are subject to a representative Weibull distribution according to the theory of sequential fragmentation, which is well known in the continued comminution of ore grinding. To delineate the spatial structure of the grain image, we present a method of multiscale and omnidirectional Gaussian derivative filtering. Then, a product quality classifier based on sparse multikernel-least squares support vector machine is proposed to solve the low-confidence classification problem of imbalanced data distribution. The proposed method is applied on the assembly line of a food-processing enterprise to classify (or identify) automatically the production quality of rice. The experiments on the real application case, compared with the commonly used methods, illustrate the validity of our method.

  4. Verifying Architectural Design Rules of the Flight Software Product Line

    Science.gov (United States)

    Ganesan, Dharmalingam; Lindvall, Mikael; Ackermann, Chris; McComas, David; Bartholomew, Maureen

    2009-01-01

    This paper presents experiences of verifying architectural design rules of the NASA Core Flight Software (CFS) product line implementation. The goal of the verification is to check whether the implementation is consistent with the CFS architectural rules derived from the developer's guide. The results indicate that consistency checking helps a) identifying architecturally significant deviations that were eluded during code reviews, b) clarifying the design rules to the team, and c) assessing the overall implementation quality. Furthermore, it helps connecting business goals to architectural principles, and to the implementation. This paper is the first step in the definition of a method for analyzing and evaluating product line implementations from an architecture-centric perspective.

  5. Reticle inspection equipment productivity increase using SEMI specification for reticle and pod management

    Science.gov (United States)

    Taylor, Ron; Downey, Jack; Wood, Jeffrey; Lin, Yen-Hung; Bugata, Bharathi; Fan, Dongsheng; Hess, Carl; Wylie, Mark

    2016-10-01

    In this work, the SEMI specification for reticle and pod management (E109) with internal reticle library support has been integrated for the first time on KLA-Tencor's TeronTM and TeraScanTM reticle inspection tools. Manufacturing Execution System scheduling reticle jobs and Automated Material Handling System scheduling to transfer pods simultaneously have also been integrated and tested. GLOBALFOUNDRIES collaboratively worked with KLA-Tencor to successfully implement these capabilities. Both library and non-library scenarios have been demonstrated for comparison in a real production environment resulting in productivity increase of approximately 29% by making use of the library. Reticle re-qualification test cases were used for the comparison in this work.

  6. Evaluation of radiological safety in industrial gammagraphy services during the construction of Bolivia-Brazil gas transmission lines (GASBOL), by regulatory inspections from brazilian CNEN

    International Nuclear Information System (INIS)

    Aquino, Josilto O. de; Silva, Francisco Cesar A. da; Leocadio, Joao Carlos; Pinho, Adaugoberto S. de; Souza, Luiz Antonio C. de; Lourenco, Manoel J.; Nicola, Marcello S.; Melo, Ivan F.

    2001-01-01

    This paper presents a brief description of the Brazilian Regulatory Authority's (National Commission of Nuclear Energy - CNEN) action about safety control on industrial radioactive installations. It shows some specific radiation safety inspections that were done during the construction of the Bolivia-Brazil Gas Transmission Line (GASBOL). In this GASBOL work, it was used industrial radiography sources for weld quality control. During two years were done thirty regulatory safety inspections in these movable installations that use gamma radiography devices. As final result, it was noticed that the national system of inspection to control the safe use of radioactive sources in industrial activities is really efficient because none overexposure was detect and every CNEN's recommendations were applied by the operators. Some result about the gamma devices and violations are also showed. (author)

  7. Total productive maintenance on example of automated foundry lines

    Directory of Open Access Journals (Sweden)

    S. Kukla

    2009-07-01

    Full Text Available Within framework of the presented study one has performed analysis of stoppages in automatic foundry lines operation, and basing on assumptions from complex maintenance system has undertaken himself to develop a service maintenance schedule for machinery installed in the line. Moreover, one has presented general assumptions of TPM system operated in conditions of series and multi-series production of cast iron castings. One has constructed operational database and has elaborated a list of line stoppage causes within a year. One has proposed a possibility of implementation of manufacturing systems modeling and simulating technique in management of production machinery operation in a foundry shop. Within framework of the simulation experiment one has developed schedules of production, schedules of maintenance and has forecasted indices of general productivity of the machinery for a various scenarios of events on example of casting line having in-series structure of operational reliability. In course of the study there was implemented ARENA universal software package to modeling and simulation of the manufacturing systems.

  8. Developing Product Lines with 3rd-party components

    NARCIS (Netherlands)

    De Jonge, M.

    2007-01-01

    The trends toward product line development and toward adopting more 3rd-party software are hard to combine. The reason is that productlines demand fine control over the software (e.g., for diversity management), while 3rd-party software (almost by definition) provides only little or no control. A

  9. Using contract mechanisms to coordinate product line decisions

    NARCIS (Netherlands)

    Nalla, V.R.; Venugopal, V.; Veen, van der J.A.A.

    2008-01-01

    In this paper we design contract mechanisms to increase the efficiency of product line decisions in a Supply Chain (SC). A two stage SC with a buyer and the supplier is considered. The end consumers are comprised of two segments with different willingness to pay. The final demand and the segments’

  10. Integrating design and production planning with knowledge-based inspection planning system

    International Nuclear Information System (INIS)

    Abbasi, Ghaleb Y.; Ketan, Hussein S.; Adil, Mazen B.

    2005-01-01

    In this paper an intelligent environment to integrate design and inspection earlier to the design stage. A hybrid knowledge-based approach integrating computer-aided design (CAD) and computer-aided inspection planning (CAIP) was developed, thereafter called computer-aided design and inspection planning (CADIP). CADIP was adopted for automated dimensional inspection planning. Critical functional features were screened based on certain attributes for part features for inspection planning application. Testing the model resulted in minimizing the number of probing vectors associated with the most important features in the inspected prismatic part, significant reduction in inspection costs and release of human labor. In totality, this tends to increase customer satisfaction as a final goal of the developed system. (author)

  11. Bucket Brigades to Increase Productivity in a Luxury Assembly Line

    Directory of Open Access Journals (Sweden)

    Filippo De Carlo

    2013-08-01

    Full Text Available One of the most challenging issues in manual assembly lines is to achieve the best balance of workloads. There are many analytic approaches to solve this problem, but they are often neglected, since they are time-consuming and require high level engineering skills. Fashion bags packaging lines must comply with a number of different products with low production volumes, while the organization of the line is often under the mere responsibility of the foreman, who balances workloads in an empirical way. The aim of this work is to evaluate the effectiveness of the arrangement of bucket brigades (BBs for an assembly line of luxury handbags. To do this, it was decided to perform a testing activity in a company producing fashion handbags in order to compare the self-made design with the BBs and with a simple assembly line balancing problem algorithm. The originality of this research lies in the fact that there are no studies in the literature on BBs applied to the packaging of highly variable small batches. The results were excellent, showing the advantages of BBs in terms of flexibility, the reduction of work in the process and the ability to handle small anomalies.

  12. Aspect-Oriented Model-Driven Software Product Line Engineering

    Science.gov (United States)

    Groher, Iris; Voelter, Markus

    Software product line engineering aims to reduce development time, effort, cost, and complexity by taking advantage of the commonality within a portfolio of similar products. The effectiveness of a software product line approach directly depends on how well feature variability within the portfolio is implemented and managed throughout the development lifecycle, from early analysis through maintenance and evolution. This article presents an approach that facilitates variability implementation, management, and tracing by integrating model-driven and aspect-oriented software development. Features are separated in models and composed of aspect-oriented composition techniques on model level. Model transformations support the transition from problem to solution space models. Aspect-oriented techniques enable the explicit expression and modularization of variability on model, template, and code level. The presented concepts are illustrated with a case study of a home automation system.

  13. Modular production line optimization: The exPLORE architecture

    Directory of Open Access Journals (Sweden)

    Spinellis Diomidis D.

    2000-01-01

    Full Text Available The general design problem in serial production lines concerns the allocation of resources such as the number of servers, their service rates, and buffers given production-specific constraints, associated costs, and revenue projections. We describe the design of exPLOre: a modular, object-oriented, production line optimization software architecture. An abstract optimization module can be instantiated using a variety of stochastic optimization methods such as simulated annealing and genetic algorithms. Its search space is constrained by a constraint checker while its search direction is guided by a cost analyser which combines the output of a throughput evaluator with the business model. The throughput evaluator can be instantiated using Markovian, generalised queueing network methods, a decomposition, or an expansion method algorithm.

  14. Systematic Derivation of Static Analyses for Software Product Lines

    DEFF Research Database (Denmark)

    Midtgaard, Jan; Brabrand, Claus; Wasowski, Andrzej

    2014-01-01

    A recent line of work lifts particular verification and analysis methods to Software Product Lines (SPL). In an effort to generalize such case-by-case approaches, we develop a systematic methodology for lifting program analyses to SPLs using abstract interpretation. Abstract interpretation...... for lifting analyses and Galois connections. We prove that for analyses developed using our method, the soundness of lifting follows by construction. Finally, we discuss approximating variability in an analysis and we derive variational data-flow equations for an example analysis, a constant propagation...

  15. A Product Line Analysis for Eco-Designed Fashion Products: Evidence from an Outdoor Sportswear Brand

    OpenAIRE

    Luo Wang; Bin Shen

    2017-01-01

    With the increasing awareness of sustainability, eco-design has been an important trend in the fashion industry. Many fashion brands such as Nike, Adidas, and The North Face have developed sustainable fashion by incorporating eco-design elements. Eco-design is an important part of sustainable supply chains. In this paper, we conducted a product line analysis of eco-designed products from a famous outdoor sportswear brand, Patagonia. We collected Patagonia’s 2017 Spring Season product line dat...

  16. Additive Manufacturing Infrared Inspection

    Science.gov (United States)

    Gaddy, Darrell; Nettles, Mindy

    2015-01-01

    The Additive Manufacturing Infrared Inspection Task started the development of a real-time dimensional inspection technique and digital quality record for the additive manufacturing process using infrared camera imaging and processing techniques. This project will benefit additive manufacturing by providing real-time inspection of internal geometry that is not currently possible and reduce the time and cost of additive manufactured parts with automated real-time dimensional inspections which deletes post-production inspections.

  17. Radioactivity inspection of Taiwan for food products imported from Japan after the Fukushima nuclear accident

    International Nuclear Information System (INIS)

    Chiu, Huang-Sheng; Huang, Ping-Ji; Wuu, Jyi-Lan; Wang, Jeng-Jong

    2013-01-01

    The 3–11 Earthquake occurred in Japan last year had greatly damaged the lives and properties and also caused the core meltdown accident in the Fukushima nuclear power plant followed by the leakage of radioactive materials into biosphere. In order to protect against the detriment of radiation from foods which were imported from Japan, the Institute of Nuclear Energy Research (INER) in Taiwan started to conduct radioactivity inspection of food products from Japan after the accident. A total of about 20,000 samples had been tested from March 24 2011 to March 31 2012. - Highlights: • About 20,000 food products imported from Japan were tested by low-background HPGe detectors. • In total, 46 food products had been found to be contaminated by I-131, Cs-134 or Cs-137, however, the radiation levels were all below the limit of Taiwanese regulations. • The measurement techniques described in this study can be used as a fast screening tool to ensure safety of food supplied

  18. A review paper on offline inspection of finished and semi-finished products and emerging research directions

    Directory of Open Access Journals (Sweden)

    Babar Ramzan Muhammad

    2016-01-01

    Full Text Available Organizations want to focus on product quality along with productivity to get their competitive advantage in global market. In order to achieve this aim, quality management system and its different aspects are becoming more valuable than before. This study has considered quality control and its activities with specific focus on offline inspection. The objective of this study is to provide a literature review that identifies different models and methodologies, developed for offline inspection under different manufacturing and inspection conditions. This review is based on research work accepted by international journals and published in the years from 2000 to 2016. These studies are classified into six groups on the basis of their research objectives, model developed, adopted methodologies, and research outcomes. This review paper also gives а brief look at the offline inspection to propose future research opportunities and emerging trends. The proposed research directions can be helpful in developing new models or modifying the existing models to improve the performance of offline inspection.

  19. Towards Product Lining Model-Driven Development Code Generators

    OpenAIRE

    Roth, Alexander; Rumpe, Bernhard

    2015-01-01

    A code generator systematically transforms compact models to detailed code. Today, code generation is regarded as an integral part of model-driven development (MDD). Despite its relevance, the development of code generators is an inherently complex task and common methodologies and architectures are lacking. Additionally, reuse and extension of existing code generators only exist on individual parts. A systematic development and reuse based on a code generator product line is still in its inf...

  20. LEAFY TURNIP IS A NEW CROP FOR SALAD PRODUCTION LINES

    OpenAIRE

    V. A. Stepanov; S. M. Sirota; O. V. Antipova

    2015-01-01

    The collaborative work on growing of leafy turnip in condition of salad production line was conducted in ООО PKF «AGROTIP». The possibility of obtaining of ecologically safety salad turnip of cv. Selekta, Sapfir, and Biryuza at hydroponic system are shown. Data of yield, productivity, and content of ascorbic acid in green leaf of turnip growing in condition of flow hydroponic system are presented. The possibilities of using of tested turnip varieties in modern agrotechnological systems are di...

  1. 46 CFR 159.007-7 - Application for acceptance for production inspections and tests: Coast Guard action.

    Science.gov (United States)

    2010-10-01

    ... and tests: Coast Guard action. 159.007-7 Section 159.007-7 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL APPROVAL....007-7 Application for acceptance for production inspections and tests: Coast Guard action. (a) From...

  2. DEVELOPMENT AND APPLICATION OF THE KEY TECHNOLOGIES FOR THE QUALITY CONTROL AND INSPECTION OF NATIONAL GEOGRAPHICAL CONDITIONS SURVEY PRODUCTS

    Directory of Open Access Journals (Sweden)

    Y. Zhao

    2018-04-01

    Full Text Available The First National Geographical Condition Survey is a predecessor task to dynamically master basic situations of the nature, ecology and human activities on the earth’s surface and it is the brand-new mapping geographic information engineering. In order to ensure comprehensive, real and accurate survey results and achieve the quality management target which the qualified rate is 100 % and the yield is more than 80 %, it is necessary to carry out the quality control and result inspection for national geographical conditions survey on a national scale. To ensure that achievement quality meets quality target requirements, this paper develops the key technology method of “five-in-one” quality control that is constituted by “quality control system of national geographical condition survey, quality inspection technology system, quality evaluation system, quality inspection information management system and national linked quality control institutions” by aiming at large scale, wide coverage range, more undertaking units, more management levels, technical updating, more production process and obvious regional differences in the national geographical condition survey and combining with novel achievement manifestation, complicated dependency, more special reference data, and large data size. This project fully considering the domestic and foreign related research results and production practice experience, combined with the technology development and the needs of the production, it stipulates the inspection methods and technical requirements of each stage in the quality inspection of the geographical condition survey results, and extends the traditional inspection and acceptance technology, and solves the key technologies that are badly needed in the first national geographic survey.

  3. Potential Errors and Test Assessment in Software Product Line Engineering

    Directory of Open Access Journals (Sweden)

    Hartmut Lackner

    2015-04-01

    Full Text Available Software product lines (SPL are a method for the development of variant-rich software systems. Compared to non-variable systems, testing SPLs is extensive due to an increasingly amount of possible products. Different approaches exist for testing SPLs, but there is less research for assessing the quality of these tests by means of error detection capability. Such test assessment is based on error injection into correct version of the system under test. However to our knowledge, potential errors in SPL engineering have never been systematically identified before. This article presents an overview over existing paradigms for specifying software product lines and the errors that can occur during the respective specification processes. For assessment of test quality, we leverage mutation testing techniques to SPL engineering and implement the identified errors as mutation operators. This allows us to run existing tests against defective products for the purpose of test assessment. From the results, we draw conclusions about the error-proneness of the surveyed SPL design paradigms and how quality of SPL tests can be improved.

  4. Analysis of the structure of a product line of alcoholic beverages

    NARCIS (Netherlands)

    Agalarova, C.; Askadullina, A.; Tilburg, van A.

    2012-01-01

    AB This article deals with marketing decisions on the optimal product line of alcoholic beverages manufactured under the brand name «Praskoveyskoe». KEY WORDS Product line, turnover analysis, ABC-analysis, production of alcoholic beverages, policy to optimize a product line INTRODUCTION A product

  5. Effects of irradiation on cytokine production in glioma cell lines

    Energy Technology Data Exchange (ETDEWEB)

    Yamanaka, Ryuya; Tanaka, Ryuichi; Yoshida, Seiichi [Niigata Univ. (Japan). Brain Research Inst.

    1993-11-01

    The effects of irradiation on cytokine production in glioma cell lines, NP1, NP2 and NP3, were studied. Culture supernatants were collected after 6, 24, 48 or 72 hours and the concentrations of interleukin (IL)-6 and IL-8 measured by enzyme-linked immunosorbent assay. Spontaneous and IL-1[beta]-stimulated productions were analyzed. Some cells were given a single dose of Lineac irradiation (10 or 20 Gy). Production of IL-6 (with or without IL-1[beta] stimulation) increased gradually to a maximum after 72 hours, more in the 20 Gy-irradiated cells than 10 Gy cells (p<0.01). Production of IL-8 increased gradually to a maximum after 48 or 72 hours. Spontaneous production of IL-8 increased more in 20 Gy-irradiated cells than 10 Gy cells after 6 and 24 hours (p<0.01), but increased more in 10 Gy cells than 20 Gy cells after 48 and 72 hours (p<0.01). The production of IL-8 stimulated by IL-1[beta] increased more in 10 Gy cells than 20 Gy cells 24 hours later (p<0.01). IL-6 and IL-8 production differed in the response to irradiation. Our data suggest that bidirectional communication between the immune system and glioma cells changes after radiotherapy. (author).

  6. Study of the on line radioactive multicharged ion production

    International Nuclear Information System (INIS)

    Lecesne, N.

    1997-01-01

    This work is directly related to the SPIRAL project (Systeme de Production d'Ions Radioactifs Acceleres en Ligne) which will start at GANIL at the end of 1998. The aim of the thesis was to study the on line radioactive multicharged ion beam production stages, i.e. the production and diffusion of the radioactive nuclei in a thick target, their possible transfer up to an ECR ion source and their ionisation. Production cross sections of radioactive neutron rich nuclei, formed by fragmentation of a heavy ion beam in a thick target, were measured. An external target-ECR source system, dedicated to the radioactive noble gases production, and two internal target-ECR source systems, dedicated to the radioactive condensable element production, were built and tested on the SIRa tests bench (Separateur d'Ions Radioactifs). Different detection configurations were elaborated in order to identify the radioactive nuclei and estimate their production yields. Finally, a new method for measuring the overall efficiency of the separator was developed and allowed to study the diffusion properties of radioactive noble gases in various targets. (author)

  7. Automated ultrasonic inspection of IGSCC in DOE production reactor process water piping

    International Nuclear Information System (INIS)

    Harrison, J.M.; Sprayberry, R.; Ehrhart, W.

    1987-01-01

    Inspection of nuclear power components has always presented difficulties to the nondestructive testing (NDT) industry from a time consumption and radiation exposure standpoint. Recent advances in computerized NDT equipment have improved the situation to some extent; however, the need for high reliability, precision, reproducibility, and clear permanent documentation are indispensable requirements that can only be met by automatic inspection and recording systems. The Savannah River Plant's inspection program of over 1000 IGSCC-susceptible welds is one of the most complete in the country and offers educational insight into ultrasonic examination technology of thin-wall stainless steel pipe welds

  8. Software product lines using FODA: a formal approach

    OpenAIRE

    Camacho González , Carlos

    2012-01-01

    El término línea de producción en inglés product line evoca a menudo la imagen de una fábrica de coches con un conjunto de brazos mecánicos especializados en colocar piezas, o tareas específicas como atornillar, soldar o ensamblar para conseguir, como producto final, un coche de manera rápida, invirtiendo la menor cantidad de recursos posibles, entre ellos, tiempo y dinero. Esta metodología se ha aplicado en contextos totalmente diferentes a la fabricación de coches, como por ejemplo en el...

  9. A/T test system for production line; Seisan line yo A/T test system

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-10

    This paper introduces an A/T test system for production line made by Meidensha, Inc. Rates and technology of mounting auto-transmissions (A/T) in recent automobiles are improving year after year. A/T production line testers were fabricated and supplied, including those for European countries. This system has the following features: the system employs low inertia AC motor, and is capable of performing tests in close conditions to actual cars; an insulated gate bipolar transistor (IGBT) inverter was employed to achieve control accuracy improvement and noise reduction; high-velocity transient measurement is possible by using a computer system based on the WindowsNT; a solenoid current slant control was employed to respond to electronically controlled A/T; and noise and vibration shift feeling instrumentation can also be used on option. Number of supply is four sets of front engine/front wheel drive (FF) car A/T testers for overseas countries, and two sets of FF A/T tests for use in Japan. (NEDO)

  10. Production Time Loss Reduction in Sauce Production Line by Lean Six Sigma Approach

    Science.gov (United States)

    Ritprasertsri, Thitima; Chutima, Parames

    2017-06-01

    In all industries, time losses, which are incurred in processing are very important. As a result, losses are incurred in productivity and cost. This research aimed to reduce lost time that occurs in sauce production line by using the lean six sigma approach. The main objective was to reduce the time for heating sauce which causes a lot of time lost in the production line which affects productivity. The methodology was comprised of the five-phase improvement model of Six Sigma. This approach begins with defining phase, measuring phase, analysing phase, improving phase and controlling phase. Cause-and-effect matrix and failure mode and effect analysis (FMEA) were adopted to screen the factors which affect production time loss. The results showed that the percentage of lost time from heating sauce reduced by 47.76%. This increased productivity to meet the plan.

  11. Simulation-based comparisons of four apparel cell production modes of one clothing production line

    Directory of Open Access Journals (Sweden)

    Guoqiang Pan

    2014-10-01

    Full Text Available Purpose: This research, by using the SIMIO simulation platform, provides a quantitative and comparative analysis of how the efficiency of four different cell production modes is affected. It is hoped that the outcomes will be of some help for garment factories to optimize their production lines. Design/methodology/approach: The SIMIO simulation platform was employed in the research and comparisons were made of the simulation test results about the four different production modes. Findings: The operation mode, number of operators, and number of buffer areas are key factors affecting the production line efficiency, and need to be reasonably set to achieve the highest efficiency. Originality/value: As most research literature so far is qualitative, this research provided a simulation-based quantitative analysis of the production efficiency under different cell production modes.

  12. Routine inspection effort required for verification of a nuclear material production cutoff convention

    International Nuclear Information System (INIS)

    Fishbone, L.G.; Sanborn, J.

    1994-12-01

    Preliminary estimates of the inspection effort to verify a Nuclear Material Cutoff Convention are presented. The estimates are based on (1) a database of about 650 facilities a total of eight states, i.e., the five nuclear-weapons states and three ''threshold'' states; (2) typical figures for inspection requirements for specific facility types derived from IAEA experience, where applicable; and (3) alternative estimates of inspection effort in cutoff options where full IAEA safeguards are not stipulated. Considerable uncertainty must be attached to the effort estimates. About 50--60% of the effort for each option is attributable to 16 large-scale reprocessing plants assumed to be in operation in the eight states; it is likely that some of these will be shut down by the time the convention enters into force. Another important question involving about one third of the overall effort is whether Euratom inspections in France and the U.K. could obviate the need for full-scale IAEA inspections at these facilities. Finally, the database does not yet contain many small-scale and military-related facilities. The results are therefore not presented as predictions but as the consequences of alternative assumptions. Despite the preliminary nature of the estimates, it is clear that a broad application of NPT-like safeguards to the eight states would require dramatic increases in the IAEA's safeguards budget. It is also clear that the major component of the increased inspection effort would occur at large reprocessing plants (and associated plutonium facilities). Therefore, significantly bounding the increased effort requires a limitation on the inspection effort in these facility types

  13. 78 FR 62584 - Certain Lined Paper Products From India: Preliminary Results of Countervailing Duty...

    Science.gov (United States)

    2013-10-22

    ... DEPARTMENT OF COMMERCE International Trade Administration [C-533-844] Certain Lined Paper Products... (CVD) order on certain lined paper products from India. The period of review (POR) is January 1, 2011...-1503. Scope of the Order The merchandise subject to the Lined Paper Order \\1\\ is certain lined paper...

  14. 40 CFR 1045.305 - How must I prepare and test my production-line engines?

    Science.gov (United States)

    2010-07-01

    ... production-line engines? 1045.305 Section 1045.305 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM SPARK-IGNITION PROPULSION MARINE ENGINES AND VESSELS Testing Production-line Engines § 1045.305 How must I prepare and test my production-line engines...

  15. 40 CFR 1048.305 - How must I prepare and test my production-line engines?

    Science.gov (United States)

    2010-07-01

    ... production-line engines? 1048.305 Section 1048.305 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM NEW, LARGE NONROAD SPARK-IGNITION ENGINES Testing Production-line Engines § 1048.305 How must I prepare and test my production-line engines? This...

  16. 77 FR 61742 - Certain Lined Paper Products From India: Preliminary Results of Countervailing Duty...

    Science.gov (United States)

    2012-10-11

    ... DEPARTMENT OF COMMERCE International Trade Administration [C-533-844] Certain Lined Paper Products... order on certain lined paper products from India. The period of review (POR) is January 1, 2010, through... (202) 482-1009. Scope of the Order The merchandise subject to the order is certain lined paper products...

  17. Productivity improvement in the production line with lean manufacturing approach: case study PT. XYZ

    Directory of Open Access Journals (Sweden)

    diah Halimatussa’

    2018-01-01

    Full Text Available The increaseing productivity is one of the competitive strategies that can be applied in a company in order to survive in an intense competitive presure. PT. XYZ is a textile industry manufacturing golf gloves and caddy bag. Every day, the company has a production target of 600 pieces per line. However, the desired target is not achieved that it will affect the delay in delivery of products to customers. In this research, a case study on implementing value stream mapping and Kaizen as the lean manufacturing concept is reported. The purpose of this study is to map the current production line, analyse and design the future value stream mapping by eliminating waste occured. It is obtained a lead time reduction as much as 440.4 seconds through eliminating 17 non-value added activities. Then, the output can be increased up to 21% which is equal to 502 pieces.

  18. A Product Line Analysis for Eco-Designed Fashion Products: Evidence from an Outdoor Sportswear Brand

    Directory of Open Access Journals (Sweden)

    Luo Wang

    2017-07-01

    Full Text Available With the increasing awareness of sustainability, eco-design has been an important trend in the fashion industry. Many fashion brands such as Nike, Adidas, and The North Face have developed sustainable fashion by incorporating eco-design elements. Eco-design is an important part of sustainable supply chains. In this paper, we conducted a product line analysis of eco-designed products from a famous outdoor sportswear brand, Patagonia. We collected Patagonia’s 2017 Spring Season product line data and analyzed the data through descriptive analysis, factor analysis and correlation analysis. We found that Patagonia mainly uses organic, recycled, and traceable materials in their eco-product line development. We identified that the usage of eco-materials may significantly affect the number of color choices and product weight as well as gender difference, pattern design, product fit and online reviewers’ opinions at Patagonia. We argued that Patagonia should focus on functionality more than aesthetics in eco-design. We discussed how sustainable fashion firms should manage eco-design in the supply chain.

  19. The Evaluation of the Products Examined within the Scope of the Market Surveillance and Inspection of Biocidal Product in the City of Çorum

    OpenAIRE

    Yapar, Zafer; Terzi, Özlem; Türkmen, Elif Nur

    2015-01-01

    Objective: In this study, it was aimed that the variety of the products examined within the scope of the market surveillance of biocidal products performed. Method: In this study planned to be of a descriptive nature, the data were obtained through a retrospective examination of the biocidal product inspection forms filled out in the City of Çorum within the scope of the Legislation of Biocidal Products dated 2013-14. Findings: In the course of the studies performed, it was determined that an...

  20. 46 CFR 159.007-5 - Production inspections and tests: Application for acceptance.

    Science.gov (United States)

    2010-10-01

    ... acceptance. 159.007-5 Section 159.007-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL APPROVAL OF EQUIPMENT AND MATERIALS...) Is accepted by the Commandant for approval inspections and tests of the equipment or material under...

  1. 46 CFR 159.007-3 - Production inspections and tests: Independent laboratory's procedures.

    Science.gov (United States)

    2010-10-01

    ...'s procedures. 159.007-3 Section 159.007-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL APPROVAL OF EQUIPMENT AND... meets the inspection and test procedures of the laboratory; and (3) Are accepted by the Commandant under...

  2. 50 CFR 260.97 - Conditions for providing fishery products inspection service at official establishments.

    Science.gov (United States)

    2010-10-01

    ... processed foods and/or components thereof; (10) Furnish and provide laundry service, as required by NMFS... inspection service at official establishments. 260.97 Section 260.97 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE PROCESSED FISHERY...

  3. Induction heating in in-line strip production process

    International Nuclear Information System (INIS)

    Costa, P.; Santinelli, M.

    1995-05-01

    ISP (In-line Strip Production), a continuous process for steel strip production, has recently been set in an italian innovative plant, where ecological impact and power requirements are lighter than usual. This report describes the studies performed by ENEA (Italian Agency for New Technologies, Energy and the Environment), while a prototype reheating facility was arranged by Acciaieria ISP in Cremona (Italy). The authors, after a study of the prototype electromagnetic field, calculate the heating rate, with the thermal network method. Then they detect, with a 1-D-FEM, the heat diffusion through the strip cross section. Afterward, since the heat distribution depends on the eddy current density one, which is given by the magnetic field distribution, the authors, with a 3-D-FEM, carry out a coupled, electromagnetic and thermal, analysis in time domain. The strip temperature map is established by the balance between skin depth heating and surface cooling: a thermal analysis, performed with a moving 2-D-FEM, take into account the effects of the different heating and cooling situations, originated by the strip moving at a speed of 6m/min through four consecutive reheating facilities. The temperatures of a strip sample heated by the prototype have been monitored, acquired by a computer and related with the simulation results. The little difference between experiment and simulation assessed the qualitative and quantitative validity of this analysis, that has come out to be a tool, useful to evaluate the effects of possible improvements to the ISP process

  4. Systems, methods and apparatus for developing and maintaining evolving systems with software product lines

    Science.gov (United States)

    Hinchey, Michael G. (Inventor); Rash, James L. (Inventor); Pena, Joaquin (Inventor)

    2011-01-01

    Systems, methods and apparatus are provided through which an evolutionary system is managed and viewed as a software product line. In some embodiments, the core architecture is a relatively unchanging part of the system, and each version of the system is viewed as a product from the product line. Each software product is generated from the core architecture with some agent-based additions. The result may be a multi-agent system software product line.

  5. Managing the Evolution of an Enterprise Architecture using a MAS-Product-Line Approach

    Science.gov (United States)

    Pena, Joaquin; Hinchey, Michael G.; Resinas, manuel; Sterritt, Roy; Rash, James L.

    2006-01-01

    We view an evolutionary system ns being n software product line. The core architecture is the unchanging part of the system, and each version of the system may be viewed as a product from the product line. Each "product" may be described as the core architecture with sonre agent-based additions. The result is a multiagent system software product line. We describe an approach to such n Software Product Line-based approach using the MaCMAS Agent-Oriented nzethoclology. The approach scales to enterprise nrchitectures as a multiagent system is an approprinre means of representing a changing enterprise nrchitectclre nnd the inferaction between components in it.

  6. Using artificial intelligence strategies for process-related automated inspection in the production environment

    Science.gov (United States)

    Anding, K.; Kuritcyn, P.; Garten, D.

    2016-11-01

    In this paper a new method for the automatic visual inspection of metallic surfaces is proposed by using Convolutional Neural Networks (CNN). The different combinations of network parameters were developed and tested. The obtained results of CNN were analysed and compared with the results of our previous investigations with color and texture features as input parameters for a Support Vector Machine. Advantages and disadvantages of the different classifying methods are explained.

  7. The challenges encountered in the integration of an early test wafer surface scanning inspection system into a 450mm manufacturing line

    Science.gov (United States)

    Lee, Jeffrey; McGarvey, Steve

    2013-04-01

    The introduction of early test wafer (ETW) 450mm Surface Scanning Inspection Systems (SSIS) into Si manufacturing has brought with it numerous technical, commercial, and logistical challenges on the path to rapid recipe development and subsequent qualification of other 450mm wafer processing equipment. This paper will explore the feasibility of eliminating the Polystyrene Latex Sphere deposition process step and the subsequent creation of SSIS recipes based upon the theoretical optical properties of both the SSIS and the process film stack(s). The process of Polystyrene Latex Sphere deposition for SSIS recipe generation and development is generally accepted on the previous technology nodes for 150/200/300mm wafers. PSL is deposited with a commercially available deposition system onto a non-patterned bare Si or non-patterned filmed Si wafer. After deposition of multiple PSL spots, located in different positions on a wafer, the wafer is inspected on a SSIS and a response curve is generated. The response curve is based on the the light scattering intensity of the NIST certified PSL that was deposited on the wafer. As the initial 450mm Si wafer manufacturing began, there were no inspection systems with sub-90nm sensitivities available for defect and haze level verification. The introduction of a 450mm sub-30nm inspection system into the manufacturing line generated instant challenges. Whereas the 450mm wafers were relatively defect free at 90nm, at 40nm the wafers contained several hundred thousand defects. When PSL was deposited onto wafers with these kinds of defect levels, PSL with signals less than the sub-90nm defects were difficult to extract. As the defectivity level of the wafers from the Si suppliers rapidly improves the challenges of SSIS recipe creation with high defectivity decreases while at the same time the cost of PSL deposition increases. The current cost per wafer is fifteen thousand dollars for a 450mm PSL deposition service. When viewed from the

  8. In-Line Acoustic Device Inspection of Leakage in Water Distribution Pipes Based on Wavelet and Neural Network

    Directory of Open Access Journals (Sweden)

    Dileep Kumar

    2017-01-01

    Full Text Available Traditionally permanent acoustic sensors leak detection techniques have been proven to be very effective in water distribution pipes. However, these methods need long distance deployment and proper position of sensors and cannot be implemented on underground pipelines. An inline-inspection acoustic device is developed which consists of acoustic sensors. The device will travel by the flow of water through the pipes which record all noise events and detect small leaks. However, it records all the noise events regarding background noises, but the time domain noisy acoustic signal cannot manifest complete features such as the leak flow rate which does not distinguish the leak signal and environmental disturbance. This paper presents an algorithm structure with the modularity of wavelet and neural network, which combines the capability of wavelet transform analyzing leakage signals and classification capability of artificial neural networks. This study validates that the time domain is not evident to the complete features regarding noisy leak signals and significance of selection of mother wavelet to extract the noise event features in water distribution pipes. The simulation consequences have shown that an appropriate mother wavelet has been selected and localized to extract the features of the signal with leak noise and background noise, and by neural network implementation, the method improves the classification performance of extracted features.

  9. Inspection indications, stress corrosion cracks and repair of process piping in nuclear materials production reactors

    International Nuclear Information System (INIS)

    Louthan, M.R. Jr.; West, S.L.; Nelson, D.Z.

    1991-01-01

    Ultrasonic inspection of Schedule 40 Type 304 stainless steel piping in the process water system of the Savannah River Site reactors has provided indications of discontinuities in less than 10% of the weld heat affected zones. Pipe sections containing significant indications are replaced with Type 304L components. Post removal metallurgical evaluation showed that the indications resulted from stress corrosion cracking in weld heat-affected zones and that the overall weld quality was excellent. The evaluation also revealed weld fusion zone discontinuities such as incomplete penetration, incomplete fusion, inclusions, underfill at weld roots and hot cracks. Service induced extension of these discontinuities was generally not significant although stress corrosion cracking in one weld fusion zone was noted. One set of UT indications was caused by metallurgical discontinuities at the fusion boundary of an extra weld. This extra weld, not apparent on the outer pipe surface, was slightly overlapping and approximately parallel to the weld being inspected. This extra weld was made during a pipe repair, probably associated with initial construction processes. The two nearly parallel welds made accurate assessment of the UT signal difficult. The implications of these observations to the inspection and repair of process water systems of nuclear reactors is discussed

  10. Automatic inspection Pads second generation; Inspeccion automatica de pastillas de segunda generacion

    Energy Technology Data Exchange (ETDEWEB)

    Gallardo-Lancho gonzalez, J. F.

    2010-07-01

    In recent years, development has addressed Enusa a second generation robot for automatic inspection of tablets incorporating the following advances: more advanced systems that improve vision quality inspection equipment, conducting the inspection in line with the grinding operation, increased productivity of the inspection process to be unnecessary pills buildup in trays and lay-out of the most rational equipment allowing cleaning it easier and faster. This second generation machine is already part of the automatic inspection equipment developed by Enusa and is an example of the ongoing commitment to the development Enusa and innovation in nuclear technology.

  11. A first-generation software product line for data acquisition systems in astronomy

    Science.gov (United States)

    López-Ruiz, J. C.; Heradio, Rubén; Cerrada Somolinos, José Antonio; Coz Fernandez, José Ramón; López Ramos, Pablo

    2008-07-01

    This article presents a case study on developing a software product line for data acquisition systems in astronomy based on the Exemplar Driven Development methodology and the Exemplar Flexibilization Language tool. The main strategies to build the software product line are based on the domain commonality and variability, the incremental scope and the use of existing artifacts. It consists on a lean methodology with little impact on the organization, suitable for small projects, which reduces product line start-up time. Software Product Lines focuses on creating a family of products instead of individual products. This approach has spectacular benefits on reducing the time to market, maintaining the know-how, reducing the development costs and increasing the quality of new products. The maintenance of the products is also enhanced since all the data acquisition systems share the same product line architecture.

  12. 9 CFR 314.7 - Carcasses of livestock condemned on ante-mortem inspection not to pass through edible product areas.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Carcasses of livestock condemned on... DISPOSAL OF CONDEMNED OR OTHER INEDIBLE PRODUCTS AT OFFICIAL ESTABLISHMENTS § 314.7 Carcasses of livestock condemned on ante-mortem inspection not to pass through edible product areas. Carcasses of livestock which...

  13. Integrated configurable equipment selection and line balancing for mass production with serial-parallel machining systems

    Science.gov (United States)

    Battaïa, Olga; Dolgui, Alexandre; Guschinsky, Nikolai; Levin, Genrikh

    2014-10-01

    Solving equipment selection and line balancing problems together allows better line configurations to be reached and avoids local optimal solutions. This article considers jointly these two decision problems for mass production lines with serial-parallel workplaces. This study was motivated by the design of production lines based on machines with rotary or mobile tables. Nevertheless, the results are more general and can be applied to assembly and production lines with similar structures. The designers' objectives and the constraints are studied in order to suggest a relevant mathematical model and an efficient optimization approach to solve it. A real case study is used to validate the model and the developed approach.

  14. Manufacturing lines under surplus-based control : multiple products and bounded buffers

    NARCIS (Netherlands)

    Starkov, K.; Pogromskiy, A.Y.; Adan, I.J.B.F.

    2015-01-01

    Challenged by the scheduling complexity for production flow processes in industrial facilities, we study the performance of multi-product producing lines. We analyse the performance of multi-product lines that consist a number of machines and bounded buffers with preselected base stock levels. It is

  15. Simulation and optimization of logistics distribution for an engine production line

    Energy Technology Data Exchange (ETDEWEB)

    Song, L.; Jin, S.; Tang, P.

    2016-07-01

    In order to analyze and study the factors about Logistics distribution system, solve the problems of out of stock on the production line and improve the efficiency of the assembly line. Using the method of industrial engineering, put forward the optimization scheme of distribution system. The simulation model of logistics distribution system for engine assembly line was build based on Witness software. The optimization plan is efficient to improve Logistics distribution efficiency, production of assembly line efficiency and reduce the storage of production line. Based on the study of the modeling and simulation of engine production logistics distribution system, the result reflects some influence factors about production logistics system, which has reference value to improving the efficiency of the production line. (Author)

  16. Simulation and optimization of logistics distribution for an engine production line

    Directory of Open Access Journals (Sweden)

    Lijun Song

    2016-02-01

    Full Text Available Purpose: In order to analyze and study the factors about Logistics distribution system, solve the problems of out of stock on the production line and improve the efficiency of the assembly line. Design/methodology/approach: Using the method of industrial engineering, put forward the optimization scheme of distribution system. The simulation model of logistics distribution system for engine assembly line was build based on Witness software. Findings: The optimization plan is efficient to improve Logistics distribution efficiency, production of assembly line efficiency and reduce the storage of production line Originality/value: Based on the study of the modeling and simulation of engine production logistics distribution system, the result reflects some influence factors about production logistics system, which has reference value to improving the efficiency of the production line.

  17. Label inspection of approximate cylinder based on adverse cylinder panorama

    Science.gov (United States)

    Lin, Jianping; Liao, Qingmin; He, Bei; Shi, Chenbo

    2013-12-01

    This paper presents a machine vision system for automated label inspection, with the goal to reduce labor cost and ensure consistent product quality. Firstly, the images captured from each single-camera are distorted, since the inspection object is approximate cylindrical. Therefore, this paper proposes an algorithm based on adverse cylinder projection, where label images are rectified by distortion compensation. Secondly, to overcome the limited field of viewing for each single-camera, our method novelly combines images of all single-cameras and build a panorama for label inspection. Thirdly, considering the shake of production lines and error of electronic signal, we design the real-time image registration to calculate offsets between the template and inspected images. Experimental results demonstrate that our system is accurate, real-time and can be applied for numerous real- time inspections of approximate cylinders.

  18. Method of analyzing the shipping inspection water in nuclear fuels

    International Nuclear Information System (INIS)

    Ishikawa, Tatsuo; Izumoji, Yoshiaki.

    1984-01-01

    Purpose: To automatically perform radioactive-corrosion-products removing operation and thereby automatic analysis for shipping inspection water. Method: An radioactive-corrosion-product removing device has a column filled with a chelate resin layer. Shipping-inspection water as a specimen is injected from a sample-water inlet to the column, passes through the chelate resin layer, issues through the sample-water exit and is then stored once in a sample collector. The shipping inspection water sampled in the sampling collector is sent to an inspection port in an on-line or off-line manner and gamma-ray determination is made by a gamma-ray spectrum analyzer. (Horiuchi, T.)

  19. Automatic Quality Inspection of Percussion Cap Mass Production by Means of 3D Machine Vision and Machine Learning Techniques

    Science.gov (United States)

    Tellaeche, A.; Arana, R.; Ibarguren, A.; Martínez-Otzeta, J. M.

    The exhaustive quality control is becoming very important in the world's globalized market. One of these examples where quality control becomes critical is the percussion cap mass production. These elements must achieve a minimum tolerance deviation in their fabrication. This paper outlines a machine vision development using a 3D camera for the inspection of the whole production of percussion caps. This system presents multiple problems, such as metallic reflections in the percussion caps, high speed movement of the system and mechanical errors and irregularities in percussion cap placement. Due to these problems, it is impossible to solve the problem by traditional image processing methods, and hence, machine learning algorithms have been tested to provide a feasible classification of the possible errors present in the percussion caps.

  20. Engineering Mathematical Analysis Method for Productivity Rate in Linear Arrangement Serial Structure Automated Flow Assembly Line

    Directory of Open Access Journals (Sweden)

    Tan Chan Sin

    2015-01-01

    Full Text Available Productivity rate (Q or production rate is one of the important indicator criteria for industrial engineer to improve the system and finish good output in production or assembly line. Mathematical and statistical analysis method is required to be applied for productivity rate in industry visual overviews of the failure factors and further improvement within the production line especially for automated flow line since it is complicated. Mathematical model of productivity rate in linear arrangement serial structure automated flow line with different failure rate and bottleneck machining time parameters becomes the basic model for this productivity analysis. This paper presents the engineering mathematical analysis method which is applied in an automotive company which possesses automated flow assembly line in final assembly line to produce motorcycle in Malaysia. DCAS engineering and mathematical analysis method that consists of four stages known as data collection, calculation and comparison, analysis, and sustainable improvement is used to analyze productivity in automated flow assembly line based on particular mathematical model. Variety of failure rate that causes loss of productivity and bottleneck machining time is shown specifically in mathematic figure and presents the sustainable solution for productivity improvement for this final assembly automated flow line.

  1. Automated visual inspection of moving custom parts

    CSIR Research Space (South Africa)

    Davrajh, S

    2008-01-01

    Full Text Available frequencies than batched produced parts. This higher frequency of inspection significantly impacts inspection times, and inherently, production rates. An effective, diverse, accurate, robust, and time efficient method for inspecting custom parts is therefore...

  2. Aggregate Production Planning, Casestudy in a Medium-sized Industry of the Rubber Production Line in Ecuador.

    Science.gov (United States)

    Rosero-Mantilla, César; Sánchez-Sailema, Mayra; Sánchez-Rosero, Carlos; Galleguillos-Pozo, Rosa

    2017-06-01

    This research aims to improve the productivity in the rubber line of a medium-sized industry by increasing the production capacities through the use of the Aggregate Production Planning model. For this purpose an analysis of the production processes of the line was made and the aggregate plan was defined evaluating two strategies: Exact Production Plan (Zero Inventory) and Constant Workforce Plan (Vary Inventory) by studying the costs of both inventory maintenance and workforce. It was also determined how the installed capacity was used with the standards of the rubber line and measures for decreasing production costs were proposed. It was proven that only 70% of the plant capacity was being used so it could be possible to produce more units and to obtain a bigger market for the products of this line.+

  3. A Role-Playing Game for a Software Engineering Lab: Developing a Product Line

    Science.gov (United States)

    Zuppiroli, Sara; Ciancarini, Paolo; Gabbrielli, Maurizio

    2012-01-01

    Software product line development refers to software engineering practices and techniques for creating families of similar software systems from a basic set of reusable components, called shared assets. Teaching how to deal with software product lines in a university lab course is a challenging task, because there are several practical issues that…

  4. 40 CFR 1048.301 - When must I test my production-line engines?

    Science.gov (United States)

    2010-07-01

    ... engines? 1048.301 Section 1048.301 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM NEW, LARGE NONROAD SPARK-IGNITION ENGINES Testing Production-line Engines § 1048.301 When must I test my production-line engines? (a) If you produce engines...

  5. 40 CFR 1051.301 - When must I test my production-line vehicles or engines?

    Science.gov (United States)

    2010-07-01

    ... vehicles or engines? 1051.301 Section 1051.301 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM RECREATIONAL ENGINES AND VEHICLES Testing Production-Line Vehicles and Engines § 1051.301 When must I test my production-line vehicles or engines? (a...

  6. 40 CFR 1045.301 - When must I test my production-line engines?

    Science.gov (United States)

    2010-07-01

    ... engines? 1045.301 Section 1045.301 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM SPARK-IGNITION PROPULSION MARINE ENGINES AND VESSELS Testing Production-line Engines § 1045.301 When must I test my production-line engines? (a) If you produce...

  7. 78 FR 13016 - Certain Lined Paper Products From India: Notice of Partial Rescission of Countervailing Duty...

    Science.gov (United States)

    2013-02-26

    ... DEPARTMENT OF COMMERCE International Trade Administration [C-533-844] Certain Lined Paper Products... an administrative review of the countervailing duty order on certain lined paper products from India...\\ Petitioners are the Association of American School Paper Suppliers. \\4\\ See petitioners' November 27, 2012...

  8. Feasibility Study for Installing Machine in Production Line to Avoid Particle Contamination Based on CFD Simulation

    Science.gov (United States)

    Khaokom, Adisorn; Thongsri, Jatuporn

    2017-10-01

    Ventilation system inside production line for electronic component production needs to meet the factory standard. Because it can eliminate small particles which may cause of human or machine in production as well as it can distribute the circulating air temperature uniformly. CFD is used in this research in order to study the feasibility and plan for machine layout in production line before actual installation. The simulation shows the airflow in every area inside production line. From simulation with releasing the particles from human and machine is found that this ventilation system generates airflow that makes most particles float out of the machines and no particle downs to the conveyor, it results to contamination. In addition, the simulation also shows the range of 19-26 °C air temperature that meets the factory standard. The results of this research are the parts of the data to renovate the production line to get more efficiency and proper on the production.

  9. Magnetic rubber inspection (MRI)

    International Nuclear Information System (INIS)

    Carro, L.

    1997-01-01

    Magnetic Rubber Inspection (MRI) was developed to inspect for small cracks and flaws encountered in high performance aircraft. A formula of very fine magnetic particles immersed in a room temperature curing rubber is catalysed and poured into dams (retainers) on the surface of the part to be inspected. Inducing a magnetic field then causes the particles to be drawn to discontinuities in the component under test. These indicating particles are held to the discontinuity by magnetic attraction, as the rubber cures. The solid rubber cast (Replica) is then removed and examined under a microscope for indicating lines of particle concentrations. 3 refs., 6 figs

  10. A study on low-cost, high-accuracy, and real-time stereo vision algorithms for UAV power line inspection

    Science.gov (United States)

    Wang, Hongyu; Zhang, Baomin; Zhao, Xun; Li, Cong; Lu, Cunyue

    2018-04-01

    Conventional stereo vision algorithms suffer from high levels of hardware resource utilization due to algorithm complexity, or poor levels of accuracy caused by inadequacies in the matching algorithm. To address these issues, we have proposed a stereo range-finding technique that produces an excellent balance between cost, matching accuracy and real-time performance, for power line inspection using UAV. This was achieved through the introduction of a special image preprocessing algorithm and a weighted local stereo matching algorithm, as well as the design of a corresponding hardware architecture. Stereo vision systems based on this technique have a lower level of resource usage and also a higher level of matching accuracy following hardware acceleration. To validate the effectiveness of our technique, a stereo vision system based on our improved algorithms were implemented using the Spartan 6 FPGA. In comparative experiments, it was shown that the system using the improved algorithms outperformed the system based on the unimproved algorithms, in terms of resource utilization and matching accuracy. In particular, Block RAM usage was reduced by 19%, and the improved system was also able to output range-finding data in real time.

  11. 7 CFR 57.925 - Inspection of imported eggs.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Inspection of imported eggs. 57.925 Section 57.925... AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) INSPECTION OF EGGS (EGG PRODUCTS INSPECTION ACT) Regulations Governing the Inspection of Eggs Imports § 57.925 Inspection of...

  12. On-line production of [11C]cyanogen bromide

    International Nuclear Information System (INIS)

    Westerberg, G.; Laangstroem, B.

    1997-01-01

    The electrophilic labelling precursor [ 11 C]cyanogen bromide was produced in 95% radiochemical yield (decay-corrected) from hydrogen [ 11 C]cyanide within 3 min from the end of bombardment using a simple and convenient solid-phase on-line procedure. The [ 11 C]cyanogen bromide has been used in the synthesis of a number of labelled compounds for use in positron emission tomography. (author)

  13. Development and use of dynamic product-line architectures

    NARCIS (Netherlands)

    Andersson, J; Bosch, J

    Software product families are used to shorten time-to-market, improve quality and lower cost, by means of effective reuse. The paper presents the results of case study conducted at four Swedish companies that are involved in either the development of or development with a software product family.

  14. Underground openings production line 2012. Design, production and initial state of the underground openings

    International Nuclear Information System (INIS)

    2013-08-01

    The Underground Openings Line Production Line report describes the design requirements, the design principles, the methods of construction and the target properties for the underground rooms required for the final repository. It is one of five Production Line reports, namely the: Underground Openings Line report, Canister report, Buffer report, Backfill report, Closure report. Together, these reports cover the lifespan of the underground phases of the final repository from the start of construction of the underground rooms to their closure. Posiva has developed reference methods for constructing the underground rooms. Tunnels will be constructed using the drill and blast technique, shafts will be constructed using raise boring and the deposition holes will be constructed by reverse down reaming. Underground openings will be made safe by reinforcement by using rock bolts, net or shotcrete, depending on which type of opening is being considered, and groundwater inflows will be limited by grouting. Posiva's requirements management system (VAHA) sets out the specifications for the enactment of the disposal concept at Olkiluoto under five Levels - 1 to 5, from the most generic to the most specific. In this report, the focus is on Level 4 and 5 requirements, which provide practical guidance for the construction of the underground openings. The design requirements are presented in Level 4 and the design specification in Level 5 In addition to the long-term safety-related requirements included in VAHA, there are additional requirements regarding the operation of underground openings, e.g. space requirements due to the equipment used and its maintenance, operational and fire safety. The current reference design for the disposal facility is presented based on the design requirements and design specifications. During the lifespan of the repository the reference design will be revised and updated according to the design principles as new information is available. Reference

  15. Strategic production modeling for defective items with imperfect inspection process, rework, and sales return under two-level trade credit

    Directory of Open Access Journals (Sweden)

    Aditi Khanna

    2017-01-01

    Full Text Available Quality decisions are one of the major decisions in inventory management. It affects customer’s demand, loyalty and customer satisfaction and also inventory costs. Every manufacturing process is inherent to have some chance causes of variation which may lead to some defectives in the lot. So, in order to cater the customers with faultless products, an inspection process is inevitable, which may also be prone to errors. Thus for an operations manager, maintaining the quality of the lot and the screening process becomes a challenging task, when his objective is to determine the optimal order quantity for the inventory system. Besides these operational tasks, the goal is also to increase the customer base which eventually leads to higher profits. So, as a promotional tool, trade credit is being offered by both the retailer and supplier to their respective customers to encourage more frequent and higher volume purchases. Thus taking into account of these facts, a strategic production model is formulated here to study the combined effects of imperfect quality items, faulty inspection process, rework process, sales return under two level trade credit. The present study is a general framework for many articles and classical EPQ model. An analytical method is employed which jointly optimizes the retailer’s credit period and order quantity, so as to maximize the expected total profit per unit time. To study the behavior and application of the model, a numerical example has been cited and a comprehensive sensitivity analysis has been performed. The model can be widely applicable in manufacturing industries like textile, footwear, plastics, electronics, furniture etc.

  16. A dynamic programming algorithm for the buffer allocation problem in homogeneous asymptotically reliable serial production lines

    Directory of Open Access Journals (Sweden)

    Diamantidis A. C.

    2004-01-01

    Full Text Available In this study, the buffer allocation problem (BAP in homogeneous, asymptotically reliable serial production lines is considered. A known aggregation method, given by Lim, Meerkov, and Top (1990, for the performance evaluation (i.e., estimation of throughput of this type of production lines when the buffer allocation is known, is used as an evaluative method in conjunction with a newly developed dynamic programming (DP algorithm for the BAP. The proposed algorithm is applied to production lines where the number of machines is varying from four up to a hundred machines. The proposed algorithm is fast because it reduces the volume of computations by rejecting allocations that do not lead to maximization of the line's throughput. Numerical results are also given for large production lines.

  17. Design of Control System for Flexible Packaging Bags Palletizing Production Line Based on PLC

    Science.gov (United States)

    Zheng, Huiping; Chen, Lin; Zhao, Xiaoming; Liu, Zhanyang

    Flexible packaging bags palletizing production line is to put the bags in the required area according to particular order and size, in order to finish handling, storage, loading and unloading, transportation and other logistics work of goods. Flexible packaging bags palletizing line is composed of turning bags mechanism, shaping mechanism, indexing mechanism, marshalling mechanism, pushing bags mechanism, pressing bags mechanism, laminating mechanism, elevator, tray warehouse, tray conveyor and loaded tray conveyor. Whether the whole production line can smoothly run depends on each of the above equipment and precision control among them. In this paper the technological process and the control logic of flexible packaging bags palletizing production line is introduced. Palletizing process of the production line realized automation by means of a control system based on programmable logic controller (PLC). It has the advantages of simple structure, reliable and easy maintenance etc.

  18. Inspection planning

    International Nuclear Information System (INIS)

    Korosec, D.; Levstek, M.F.

    2001-01-01

    Slovenian Nuclear Safety Administration (SNSA) division of nuclear and radiological safety inspection has developed systematic approach to their inspections. To be efficient in their efforts regarding regular and other types of inspections, in past years, the inspection plan has been developed. It is yearly based and organized on a such systematic way, that all areas of nuclear safety important activities of the licensee are covered. The inspection plan assures appropriate preparation for conducting the inspections, allows the overview of the progress regarding the areas to be covered during the year. Depending on the licensee activities and nature of facility (nuclear power plant, research reactor, radioactive waste storage, others), the plan has different levels of intensity of inspections and also their frequency. One of the basic approaches of the plan is to cover all nuclear and radiological important activities on such way, that all regulatory requests are fulfilled. In addition, the inspection plan is a good tool to improve inspection effectiveness based on previous experience and allows to have the oversight of the current status of fulfillment of planned inspections. Future improvement of the plan is necessary in the light of newest achievements on this field in the nuclear world, that means, new types of inspections are planned and will be incorporated into plan in next year.(author)

  19. LINES

    Directory of Open Access Journals (Sweden)

    Minas Bakalchev

    2015-10-01

    Full Text Available The perception of elements in a system often creates their interdependence, interconditionality, and suppression. The lines from a basic geometrical element have become the model of a reductive world based on isolation according to certain criteria such as function, structure, and social organization. Their traces are experienced in the contemporary world as fragments or ruins of a system of domination of an assumed hierarchical unity. How can one release oneself from such dependence or determinism? How can the lines become less “systematic” and forms more autonomous, and less reductive? How is a form released from modernistic determinism on the new controversial ground? How can these elements or forms of representation become forms of action in the present complex world? In this paper, the meaning of lines through the ideas of Le Corbusier, Leonidov, Picasso, and Hitchcock is presented. Spatial research was made through a series of examples arising from the projects of the architectural studio “Residential Transformations”, which was a backbone for mapping the possibilities ranging from playfulness to exactness, as tactics of transformation in the different contexts of the contemporary world.

  20. Routine inspection effort required for verification of a nuclear material production cutoff convention

    International Nuclear Information System (INIS)

    Dougherty, D.; Fainberg, A.; Sanborn, J.; Allentuck, J.; Sun, C.

    1996-11-01

    On 27 September 1993, President Clinton proposed open-quotes... a multilateral convention prohibiting the production of highly enriched uranium or plutonium for nuclear explosives purposes or outside of international safeguards.close quotes The UN General Assembly subsequently adopted a resolution recommending negotiation of a non-discriminatory, multilateral, and internationally and effectively verifiable treaty (hereinafter referred to as open-quotes the Cutoff Conventionclose quotes) banning the production of fissile material for nuclear weapons. The matter is now on the agenda of the Conference on Disarmament, although not yet under negotiation. This accord would, in effect, place all fissile material (defined as highly enriched uranium and plutonium) produced after entry into force (EIF) of the accord under international safeguards. open-quotes Productionclose quotes would mean separation of the material in question from radioactive fission products, as in spent fuel reprocessing, or enrichment of uranium above the 20% level, which defines highly enriched uranium (HEU). Facilities where such production could occur would be safeguarded to verify that either such production is not occurring or that all material produced at these facilities is maintained under safeguards

  1. Research of Control System and Fault Diagnosis of the Sound-absorbing Board Production Line

    Directory of Open Access Journals (Sweden)

    Yanjun Xiao

    2014-08-01

    Full Text Available Programmable Logic Controller is the core of the control system of the sound- absorbing board production line and the design of fault diagnosis is an essential modules in the sound- absorbing board production line. The article discourses the application of PLC in the control system of the production line, and designs the methods of grading treatment and prevention of troubles, which makes use of PLC’S logic functions. The method has good expansibility, and has good guidance to the fault diagnosis in other automation equipments.

  2. ASCE application guide for recommended practice for fiber-reinforced polymer products for overhead utility line structures

    Energy Technology Data Exchange (ETDEWEB)

    Gnandt, E. [T and D High Voltage Consulting, Vancouver, BC (Canada)

    2002-07-01

    The participants to the American Society of Civil Engineers (ASCE) prepared an application guide to provide guidelines to utilities and manufacturers on topics ranging from design to manufacture, testing and installation of fiber-reinforced polymer (FRP) products. The intent was also to help utilities with a possible replacement material for wood, steel and pre-stressed concrete. FRP products are constructed from fiber and resin and offer several advantages such as light weight and high strength-to-weight ratio, low maintenance, dimensional stability, resistance to rot, corrosion, chemicals and pest damage. FRP products can be used for lighting poles, ladders and grating, transformer pads, pole line hardware and crossarms, and other applications. There are five structural configurations: (1) cantilevered structures (single pole), (2) guyed structures, framed structures (H-Frame), (4) a combination of (1), (2), and (3), and (5) lattice structures (transmission class). The author listed some of the initial considerations: physical characteristics, guying and grounding, deflection and load testing, attached items, and durability to name only a few. The materials and manufacturing processes were briefly explained, namely the pultrusion method, the filament winding method, and the centrifugal casting method. Design loads considerations are discussed, as are performance-based criteria such as mechanical, coating durability and electrical. Quality control, assembly erection and storage, and in-service considerations are also discussed. The author concluded the presentation with a section dealing with field inspections. figs.

  3. 9 CFR 316.8 - Unmarked inspected products; moved between official establishments; moved in commerce.

    Science.gov (United States)

    2010-01-01

    ... between official establishments; moved in commerce. 316.8 Section 316.8 Animals and Animal Products FOOD... establishment to another official establishment, for further processing, in a railroad car, truck, or other closed container, if the railroad car, truck, or container is sealed with an official seal of the...

  4. Risk based inspection experience from the European chemical- and petrochemical industries

    International Nuclear Information System (INIS)

    Kristensen, Hans; Jeppesen, Leif; Larsen, Bjarne; Kim, Na Yon

    2001-01-01

    As an inspection vendor with 60 years of experience and with more than 25 years of experience as manufacturer of the Automated Ultrasonic NDT systems, the P-scan systems, FORCE Institute is continuously analysing the market for NDT. This is done to assure that both the equipment product line and the service mix provided by FORCE Institute are meeting the requirements from the industry today and in the future. The concept of Risk Based Inspection Programmes were adopted early by the offshore industry and has in the recent years been adopted by many other industries as a reliable and cost efficient way of maintaining a production facility. A Risk/Reliability Based Inspection Programme is a 'living organism' that constantly needs information if it shall be of any value and NDT information is only one type of information that is required. The NDT information required is normally related to corrosion/base material information and weld integrity information. NDT as an integrated part of a plants maintenance system is, in Europe, currently influenced by the following tendencies which all are related to 'Risk Based Inspection': · Increased use of Base-Line Inspections · Reduction in the use of repeated inspections(qualitative- instead of quantitative Inspections). · Inspection results are fed directly into the plant maintenance system. · Fitness-for-Purpose acceptance criteria instead of conventional acceptance criteria. As repeatability and accuracy is a key issue for the data, automated ultrasonic inspection is increasingly used as an alternative to manual ultrasonic inspection, but due to the physical size of most automated ultrasonic inspection systems the gain in productivity has not been as significant as the gain in repeatability and accuracy. In this paper some of FORCE Institute's practical experiences with examinations carried out in connection with Risk Based Inspection is used to illustrate the above described tendencies. Not only examples using automated

  5. 76 FR 62343 - Certain Lined Paper Products From India: Notice of Preliminary Results of Antidumping Duty...

    Science.gov (United States)

    2011-10-07

    ... Lined Paper Products from India: Selection of Respondents for Individual Review'' (Respondent Selection... purposes of determining appropriate product comparisons to U.S. sales. Because Riddhi did not have home market sales of subject merchandise during the POR, all products produced by Riddhi covered by the...

  6. Information logistics: A production-line approach to information services

    Science.gov (United States)

    Adams, Dennis; Lee, Chee-Seng

    1991-01-01

    Logistics can be defined as the process of strategically managing the acquisition, movement, and storage of materials, parts, and finished inventory (and the related information flow) through the organization and its marketing channels in a cost effective manner. It is concerned with delivering the right product to the right customer in the right place at the right time. The logistics function is composed of inventory management, facilities management, communications unitization, transportation, materials management, and production scheduling. The relationship between logistics and information systems is clear. Systems such as Electronic Data Interchange (EDI), Point of Sale (POS) systems, and Just in Time (JIT) inventory management systems are important elements in the management of product development and delivery. With improved access to market demand figures, logisticians can decrease inventory sizes and better service customer demand. However, without accurate, timely information, little, if any, of this would be feasible in today's global markets. Information systems specialists can learn from logisticians. In a manner similar to logistics management, information logistics is concerned with the delivery of the right data, to the ring customer, at the right time. As such, information systems are integral components of the information logistics system charged with providing customers with accurate, timely, cost-effective, and useful information. Information logistics is a management style and is composed of elements similar to those associated with the traditional logistics activity: inventory management (data resource management), facilities management (distributed, centralized and decentralized information systems), communications (participative design and joint application development methodologies), unitization (input/output system design, i.e., packaging or formatting of the information), transportations (voice, data, image, and video communication systems

  7. Biofuel Production: Considerations for USACE Civil Works Business Lines

    Science.gov (United States)

    2014-12-01

    feedstock for biofuel production has led to research whereby several genera of duckweed ( Lemna , Landoltia, Spirodela, Wolffia, Wolfiella) have been...as well as the general public when rendering its final permit decisions. Regulatory responsibilities include evaluating minor activities such as...reservoirs scattered along minor river systems in other parts of the United States (Kasul et al. 1998) Through a series of legislative acts in the

  8. Application of X-ray digital radiography to online automated inspection of interior assembly structures of complex products

    International Nuclear Information System (INIS)

    Han Yueping; Han Yan; Li Ruihong; Wang Liming

    2009-01-01

    The paper proposes an application of X-ray digital radiography to online automated inspection and recognition of the interior assembly structures of complex products by means of the multiple views techniques. First, a vertical hybrid projection function (VHPF) is proposed as the recognition feature of a two-dimensional image. VHPF combines an integral projection function and a standard deviation function so that it can reflect the mean and the variance of the pixels in the vertical direction in an image. Secondly, by considering the different importance grades of objects inside the product and the independence of these objects along the circumference, the paper presents a hierarchical recognition method and uses a neural network system to speed up the computation process with parallel operations. Thirdly, using the whole-orientation features of one standard swatch and by extracting its maximal system of linear independence as the feature basis, the issue of blind areas for recognition is resolved. Based on this approach, the first domestic X-ray multi-view digital detection system has been developed and applied to the online detection of objects containing complicated assembly structures.

  9. Production of high-amylose maize lines using RNA interference in ...

    African Journals Online (AJOL)

    amylose maize lines with a low T-DNA copy number, demonstrating that RNAi is an efficient method for the production of high-amylose maize lines. Key words: Maize, high-amylose, RNA interference, starch branching enzyme gene sbe2a.

  10. The role of off-line and online strategies for successful product positioning

    OpenAIRE

    Yaneva D. E.; Zlateva D. A.

    2015-01-01

    The study of the article is done on off-line and online strategies that companies use for their successful positioning. The goal is to establish the role and the significance of the strategies for successful product positioning in off-line and online environment.

  11. Guidelines for Using OAR Concepts in a DoD Product Line Acquisition Context

    National Research Council Canada - National Science Library

    Bergey, John

    2000-01-01

    Many DoD organizations are considering product line initiatives as a means of overcoming the issues of quality, cost and schedule inherent in a "one-at-a-time" system development or acquisition paradigm...

  12. Classification and calculation of primary failure modes in bread production line

    International Nuclear Information System (INIS)

    Tsarouhas, Panagiotis H.

    2009-01-01

    In this study, we describe the classification methodology over a 2-year period of the primary failure modes in categories based on failure data of bread production line. We estimate the probabilities of these categories applying the chi-square goodness of fit test, and we calculate their joint probabilities of mass function at workstation and line level. Then, we present numerical examples in order to predict the causes and frequencies of breakdowns for workstations and for the entire bread production line that will occur in the future. The methodology is meant to guide bread and bakery product manufacturers, improving the operation of the production lines. It can also be a useful tool to maintenance engineers, who wish to analyze and improve the reliability and efficiency of the manufacturing systems

  13. Parameters Investigation of Mathematical Model of Productivity for Automated Line with Availability by DMAIC Methodology

    Directory of Open Access Journals (Sweden)

    Tan Chan Sin

    2014-01-01

    Full Text Available Automated line is widely applied in industry especially for mass production with less variety product. Productivity is one of the important criteria in automated line as well as industry which directly present the outputs and profits. Forecast of productivity in industry accurately in order to achieve the customer demand and the forecast result is calculated by using mathematical model. Mathematical model of productivity with availability for automated line has been introduced to express the productivity in terms of single level of reliability for stations and mechanisms. Since this mathematical model of productivity with availability cannot achieve close enough productivity compared to actual one due to lack of parameters consideration, the enhancement of mathematical model is required to consider and add the loss parameters that is not considered in current model. This paper presents the investigation parameters of productivity losses investigated by using DMAIC (Define, Measure, Analyze, Improve, and Control concept and PACE Prioritization Matrix (Priority, Action, Consider, and Eliminate. The investigated parameters are important for further improvement of mathematical model of productivity with availability to develop robust mathematical model of productivity in automated line.

  14. Lesions found at routine meat inspection on finishing pigs are associated with production system

    DEFF Research Database (Denmark)

    Kongsted, Hanne; Sørensen, Jan Tind

    2017-01-01

    raised in conventional free-range and organic free-range production systems had higher odds for white liver-spots (ORPA, 5–7), tail lesions (ORPA, 3–4), arthritis (ORPA, 3), skin lesions (ORPA, 3), bone fractures (ORPA, 2), septicaemia (ORPA, 1.1–1.5) and abscesses (ORPA, 1.1–1.3) at slaughter. Pairwise...... correlation coefficients 21–35%) on the occurrence of white liver-spots, tail lesions, skin lesions and airway infections. These results suggest possibilities for herd-level management interventions of the problems studied...

  15. Defining project scenarios for the agile requirements engineering product-line development questionnaire

    OpenAIRE

    Feng, Kunwu; Lempert, Meli; Tang, Yan; Tian, Kun; Cooper, Kendra M.L.; Franch Gutiérrez, Javier

    2007-01-01

    Current agile methods are focused on practices of small, rapid developing and iteration, more people oriented, less documentation projects, and the use of the methods in large, product line projects are somehow difficult. UTD and GESSI have started a project to develop an expert system that can assist a requirements enginer in selecting a requirements engineering process that is well suited for their project, in particular with respect to the use of agile and product line engineering methods....

  16. Developing a survey to collect expertise in agile product line requirements engineering processes

    OpenAIRE

    Feng, Kunwu; Lempert, Meli; Tang, Yan; Tian, Kun; Cooper, Kendra M.L.; Franch Gutiérrez, Javier

    2007-01-01

    Current agile methods are focused on practices of small, rapid developing and iteration, more people oriented, less documentation projects, and the use of the methods in large, product line projects are somehow difficult. UTD and GESSI have started a project to develop an expert system that can assist a requirements enginer in selecting a requirements engineering process that is well suited for their project, in particular with respect to the use of agile and product line engineering methods....

  17. DPLFW: a Framework for the Product-Line-Based Generation of Variable Content Documents

    OpenAIRE

    Gómez , Abel; Martí , Pau; Penadés , M. Carmen; Canós , José H.

    2014-01-01

    International audience; Document Product Lines (DPL) is a document engineering methodology that applies product-line engineering principles to the gen-eration of documents in high variability contexts and with high reuse of components. Instead of standalone documents, DPL promotes the defi-nition of families of documents where the members share some common content while differ in other parts. The key for the definition is the avail-ability of a collection of content assets which can be parame...

  18. Green perspective in food industry production line design: A review

    Science.gov (United States)

    Xian, C. Y.; Sin, T. C.; Liyana, M. R. N.; Awang, A.; Fathullah, M.

    2017-09-01

    The design of green manufacturing process in food industries is currently a hot research topic in the multidisciplinary area of applied chemistry, biology and technology. Several process such as freezing, cutting, drying, tempering, bleaching, sterilization, extraction and filtering have been applied efficiency in the food industry. Due to the rapid development of food and peripheral technology, the use of new physical processing or auxiliary processing methods can maintain food inherent nutrients, texture, color, and freshness and also reduce environmental pollution and energy consumption in food processing. Hence, this review paper will study and summarize the effects of green manufacturing process in food industries in term of waste reduction, materials and sustainability manufacturing. In any case, All the food processing equipment must comply with strict standards and regulation, this action will ensure the securing the food quality and safety of food products to consumers.

  19. UO2: production based on two alternative lines

    International Nuclear Information System (INIS)

    Coppa, R.C.; Martin, H.R.

    1987-01-01

    The production of the uranium dioxide (UO 2 ) is carried out at the Cordoba factory, of the Argentine National Atomic Energy Commission, by the uranil carbonate method (AUC). The commercial uranium concentrates (yellow cake) is dissolved with HNO 3 and purificated with tributil phosphate (TBP). The pure uranium compound coming from the reextraction, is concentrated to 0.4 Kg U/l, then the precipitation with CO 2 and NH 3 gives the AUC crystalls. After conversion of AUC to UO 2 powder, the pellets are obtained by direct compacting. In the second experimental method used by CNEA, the yellow cake is dissolved with H 2 SO 4 , and then it is purified with a terciary amine and precipitated with (NH 4 ) 2 CO 3 . In this form the ammonium uranil tri-carbonate (AUT) crystals are obtained. The convertion to UO 2 is made under an atmosphere of dissociated NH 3 . (M.E.L.) [es

  20. Monitoring of fission products through on-line gamma spectrometry

    International Nuclear Information System (INIS)

    Montagnon, F.; Warlop, R.

    1989-01-01

    Under normal operating conditions, the monitoring of the possible deterioration of the pressurized water reactor core fuel rods is achieved through analysis of the radioactive fission products carried by the primary system. For acquiring results of spectrometric analyses in real time, and avoiding risks of errors linked to manual operations, CEA/DMG and EDF/SEPTEN have jointly developed an entirely automatic system. This system allows measuring permanently the primary system activity of two coupled units, with no human operation nor any handling of active coolant specimens. The PIGAL facility has been set up in the nuclear auxiliary building, common to the two units, and it is used on a demonstration basis for units 2 and 3 of the BUGEY site. This device has been patented

  1. Long-Range Piping Inspection by Ultrasonic Guided Waves

    International Nuclear Information System (INIS)

    Joo, Young Sang; Lim, Sa Hoe; Eom, Heung Seop; Kim, Jae Hee

    2005-01-01

    The ultrasonic guided waves are very promising for the long-range inspection of large structures because they can propagate a long distance along the structures such as plates, shells and pipes. The guided wave inspection could be utilized for an on-line monitoring technique when the transmitting and receiving transducers are positioned at a remote point on the structure. The received signal has the information about the integrity of the monitoring area between the transmitting and receiving transducers. On-line monitoring of a pipe line using an ultrasonic guided wave can detect flaws such as corrosion, erosion and fatigue cracking at an early stage and collect useful information on the flaws. However the guided wave inspection is complicated by the dispersive characteristics for guided waves. The phase and group velocities are a function of the frequency-thickness product. Therefore, the different frequency components of the guided waves will travel at different speeds and the shape of the received signal will changed as it propagates along the pipe. In this study, we analyze the propagation characteristics of guided wave modes in a small diameter pipe of nuclear power plant and select the suitable mode for a long-range inspection. And experiments will be carried out for the practical application of a long-range inspection in a 26m long pipe by using a high-power ultrasonic inspection system

  2. Product-line selection and pricing with remanufacturing under availability constraints

    Science.gov (United States)

    Aras, Necati; Esenduran, G.÷k.‡e.; Altinel, I. Kuban

    2004-12-01

    Product line selection and pricing are two crucial decisions for the profitability of a manufacturing firm. Remanufacturing, on the other hand, may be a profitable strategy that captures the remaining value in used products. In this paper we develop a mixed-integer nonlinear programming model form the perspective of an original equipment manufacturer (OEM). The objective of the OEM is to select products to manufacture and remanufacture among a set of given alternatives and simultaneously determine their prices so as to maximize its profit. It is assumed that the probability a customer selects a product is proportional to its utility and inversely proportional to its price. The utility of a product is an increasing function of its perceived quality. In our base model, products are discriminated by their unit production costs and utilities. We also analyze a case where remanufacturing is limited by the available quantity of collected remanufacturable products. We show that the resulting problem is decomposed into the pricing and product line selection subproblems. Pricing problem is solved by a variant of the simplex search procedure which can also handle constraints, while complete enumeration and a genetic algorithm are used for the solution of the product line selection problem. A number of experiments are carried out to identify conditions under which it is economically viable for the firm to sell remanufactured products. We also determine the optimal utility and unit production cost values of a remanufactured product, which maximizes the total profit of the OEM.

  3. Increasing Student Interest and Comprehension of Production Planning and Control and Operations Performance Measurement Concepts Using a Production Line Game

    Science.gov (United States)

    Cox, James F., III; Walker, Edward D., II

    2005-01-01

    Production planning and control (PPC) systems and operations performance measures are topics that students generally find both boring and difficult to understand. In the article, the authors present a production line game that they have found to be an effective tool to increase student interest in the topics as well as student comprehension. The…

  4. Automated PCB Inspection System

    Directory of Open Access Journals (Sweden)

    Syed Usama BUKHARI

    2017-05-01

    Full Text Available Development of an automated PCB inspection system as per the need of industry is a challenging task. In this paper a case study is presented, to exhibit, a proposed system for an immigration process of a manual PCB inspection system to an automated PCB inspection system, with a minimal intervention on the existing production flow, for a leading automotive manufacturing company. A detailed design of the system, based on computer vision followed by testing and analysis was proposed, in order to aid the manufacturer in the process of automation.

  5. —Pricing Digital Content Product Lines: A Model and Application for the National Academies Press

    OpenAIRE

    P. K. Kannan; Barbara Kline Pope; Sanjay Jain

    2009-01-01

    We examine the problem of how a content provider, specifically the National Academies Press (NAP), can optimally price the different forms of its product—print and PDF—that it sells online. Whereas products in the traditional product line generally tend to be substitutes, the different content product forms could range from being substitutes to being complements across customers. Thus the content provider can possibly sell bundles of the product forms, leading to additional revenue. We first ...

  6. LHC dipole magnets start to roll off the production line

    CERN Multimedia

    2000-01-01

    The first pre-series LHC dipole magnet has been delivered to CERN, a further 1247 are due to be produced by 2005. Their production is the result of technology transfer from CERN to its suppliers. Fifteen metres long, thirty-tonnes in weight, and using several kilometres of superconducting cable, the magnet that has just arrived in hall 181 is a true colossus. It is the first pre-series dipole that will begin service in 2005 in the future Large Hadron Collider, LHC. Delivered by the French Alstom-Jeumont Industrie consortium, it is the first of 1248 magnets that will be manufactured over the coming five years. Needless to say, lavish attention has been devoted to this magnet by the engineers and technicians who accompanied it to CERN from Belfort in north east France. The task of the dipole magnets will be to steer the LHC's proton beams on a circular trajectory around the LHC's 27 kilometre circumference. A magnetic field of 8.33 Tesla is required to guide the protons, accelerated to an energy of 7 TeV, aroun...

  7. Aminobenzoates as building blocks for natural product assembly lines.

    Science.gov (United States)

    Walsh, Christopher T; Haynes, Stuart W; Ames, Brian D

    2012-01-01

    The ortho-, meta-, and para- regioisomers of aminobenzoate are building blocks for a wide range of microbial natural products. Both the ortho-isomer (anthranilate) and PABA derive from the central shikimate pathway metabolite chorismate while the meta-isomer is not available by that route and starts from UDP-3-aminoglucose. PABA is largely funnelled into folate biosynthesis while anthranilate is the scaffold for biosynthetic elaboration into many natural heterocycles, most notably with its role in indole formation for tryptophan biosynthesis. Anthranilate is also converted to benzodiazepinones, fumiquinazolines, quinoxalines, phenoxazines, benzoxazolinates, quinolones, and phenazines, often with redox enzyme participation. The 5-hydroxy form of 3-aminobenzaote is the starter unit for ansa-bridged rifamycins, ansamitocins, and geldanamycins, whereas regioisomers 2-hydroxy, 4-hydroxy and 2,4-dihydroxy-3-aminobenzoate are key components of antimycin, grixazone, and platencin and platensimycin biosynthesis, respectively. The enzymatic mechanisms for generation of the aminobenzoate regioisomers and their subsequent utilization for diverse heterocycle and macrocycle construction are examined.

  8. Simulation of Production Lines in the Education of Engineers: How to Choose the Right Software?

    Directory of Open Access Journals (Sweden)

    Rostkowska Marta

    2014-12-01

    Full Text Available The article discusses the problems of modeling and simulation in the design of production lines, mainly from an educator's perspective. Nowadays, there is a wide range of computer programs that can be used to design production lines and to simulate various aspects of their operation. However, the programs being available vary considerably as to their functionality, the approach to production system design, and the visualization tools. Therefore we demonstrate and evaluate in this paper four simulation programs, focusing on the easiness of system design, area of the possible applications in education of engineers, and the limitations imposed by versions dedicated for students. We evaluate three of programs for digital factory simulation on a common, simple assembly task, then demonstrate that these programs may be also used for more specialized simulations in various areas of production, and compare with a specialized program for simulation of robotised production lines and work cells.

  9. Ultrasonic inspection of nodular cast iron

    International Nuclear Information System (INIS)

    Hersh, S.; Zhang, Yingda

    1990-01-01

    On the basis of experimental results collected from several nodular cast iron (NCI) specimens, Amdata, Inc., has developed a tentative procedure for performing ultrasonic testing (UT) preservice inspection of NCI casks and qualifying personnel and equipment. The authors anticipate that this procedure will be a component in a comprehensive program to certify that casks are free from critical flaws prior to their introduction into service, with testing being performed on a production line basis by UT inspection personnel. The tentative procedure was applied to inspection of NCI block SGR-483-001 manufactured by Siempelkamp Giesserei GmbH and Co. of West Germany. This block is 59 by 39.5 by 13.8 inches and weighs 5.2 tons. Several indications were detected with the I/98, in accordance with the tentative procedure, and they were analyzed using two-dimensional synthetic aperture technique (Line-SAFT). When compared with conventional sizing methods that may confound the effects of beam spread with flaw size, Line-SAFT significantly improved sizing accuracy. SAFT is an electronic simulation of a lens and has the property of reducing the effect of beam spread on the resultant indication sizes. Although a higher-precision 3-D SAFT option was also available, it would necessitate data transfer to a separate VAX computer and lengthy calculations. As an alternative, Line-SAFT, a faster but less precise 2-D simplification, was implemented on the I/98 data acquisition system

  10. An ergonomic approach to reorganize parking inspection agents' work productivity, health and safety in São Paulo, Brazil.

    Science.gov (United States)

    Gonçalves, R M A; Lancman, S; Trudel, L; Jardim, T A; Sznelwar, L I; Santos, M C; Freeman, Andrew

    2010-01-01

    The Traffic Engineering Company of the City of São Paulo (Brazil) observed a decrease in productivity, and an increase in sick leave, accidents and psychological distress among their parking inspection agents. To document this situation, qualitative research was undertaken to obtain an in-depth comprehension of work activity. Workers, managers and health and safety professionals contributed to the documentation of the problem and to the proposal of possible solutions. Ergonomic work analysis focusing on real work activity, as well as interviews with individual or groups of stakeholders, were conducted. This research revealed that political-economic factors gradually contributed to: 1) an increasing work load; 2) growing fatigue throughout the day, increasing the workers' vulnerability to incidents and accidents and their tendency to react inappropriately to violence experienced on the street; and 3) excessive individual responsibility to manage dangerous situations. Recommendations to ameliorate the situation are proposed. These suggestions are discussed in terms of feasibility given the impact of macro social factors upon micro work activity, and the associated potential expansion of the ergonomist's role.

  11. Supporting Development of Satellite's Guidance Navigation and Control Software: A Product Line Approach

    Science.gov (United States)

    McComas, David; Stark, Michael; Leake, Stephen; White, Michael; Morisio, Maurizio; Travassos, Guilherme H.; Powers, Edward I. (Technical Monitor)

    2000-01-01

    The NASA Goddard Space Flight Center Flight Software Branch (FSB) is developing a Guidance, Navigation, and Control (GNC) Flight Software (FSW) product line. The demand for increasingly more complex flight software in less time while maintaining the same level of quality has motivated us to look for better FSW development strategies. The GNC FSW product line has been planned to address the core GNC FSW functionality very similar on many recent low/near Earth missions in the last ten years. Unfortunately these missions have not accomplished significant drops in development cost since a systematic approach towards reuse has not been adopted. In addition, new demands are continually being placed upon the FSW which means the FSB must become more adept at providing GNC FSW functionality's core so it can accommodate additional requirements. These domain features together with engineering concepts are influencing the specification, description and evaluation of FSW product line. Domain engineering is the foundation for emerging product line software development approaches. A product line is 'A family of products designed to take advantage of their common aspects and predicted variabilities'. In our product line approach, domain engineering includes the engineering activities needed to produce reusable artifacts for a domain. Application engineering refers to developing an application in the domain starting from reusable artifacts. The focus of this paper is regarding the software process, lessons learned and on how the GNC FSW product line manages variability. Existing domain engineering approaches do not enforce any specific notation for domain analysis or commonality and variability analysis. Usually, natural language text is the preferred tool. The advantage is the flexibility and adapt ability of natural language. However, one has to be ready to accept also its well-known drawbacks, such as ambiguity, inconsistency, and contradictions. While most domain analysis

  12. Integrating Theory and Practice: Applying the Quality Improvement Paradigm to Product Line Engineering

    Science.gov (United States)

    Stark, Michael; Hennessy, Joseph F. (Technical Monitor)

    2002-01-01

    My assertion is that not only are product lines a relevant research topic, but that the tools used by empirical software engineering researchers can address observed practical problems. Our experience at NASA has been there are often externally proposed solutions available, but that we have had difficulties applying them in our particular context. We have also focused on return on investment issues when evaluating product lines, and while these are important, one can not attain objective data on success or failure until several applications from a product family have been deployed. The use of the Quality Improvement Paradigm (QIP) can address these issues: (1) Planning an adoption path from an organization's current state to a product line approach; (2) Constructing a development process to fit the organization's adoption path; (3) Evaluation of product line development processes as the project is being developed. The QIP consists of the following six steps: (1) Characterize the project and its environment; (2) Set quantifiable goals for successful project performance; (3) Choose the appropriate process models, supporting methods, and tools for the project; (4) Execute the process, analyze interim results, and provide real-time feedback for corrective action; (5) Analyze the results of completed projects and recommend improvements; and (6) Package the lessons learned as updated and refined process models. A figure shows the QIP in detail. The iterative nature of the QIP supports an incremental development approach to product lines, and the project learning and feedback provide the necessary early evaluations.

  13. Product-line administration: a framework for redefining medical record department services.

    Science.gov (United States)

    Postal, S N

    1990-06-01

    Product-line administration is a viable approach for managing medical records services in an environment that demands high quantity and quality service levels. Product-line administration directs medical record department team members to look outside of the department and seek input from the customers it is intended to serve. The feedback received may be alarming at first, as the current state of products usually reveals a true lack of customer input. As the planning, defining, managing, and marketing phases are implemented, the road will not be easy and rewards will be slow to come. Product-line administration does not provide quick fixes, but it does provide long-term problem resolution as products are refined and new products developed to meet customer needs and expectations. In addition to better meeting the needs of the department's external customers, the department's internal customers' needs and expectations will be addressed. The participative management approach will help nurture each team member's creativity. The team members will have the opportunity to reach their full potential while reaping the rewards and benefits of providing products and services that meet the needs and expectations of all department customers. The future of the health care industry promises more changes as the country moves toward some form of prospective payment in the ambulatory setting. Reactive management and the constant struggle to catch up can no longer be accepted as a management approach. It is imperative that the medical record department be viewed as a business with product lines composed of quality products. The planning, defining, managing, and marketing components of product-line administration afford responsiveness to the current situation and the development of quality products that will ensure that medical record departments are prepared for the future.

  14. Material flow enhancement in production assembly lines under application of zoned order picking systems

    Directory of Open Access Journals (Sweden)

    D. Živanić

    2014-10-01

    Full Text Available Introduced research work relates to the possibility of material flow enhancement in production systems, with the apostrophe on material order picking in production assembly lines. The paper presents basic rules and the results related to formed computer models of zoned order picking systems under the application of developed bound cavities method.

  15. JSI-124 inhibits IgE production in an IgE B cell line

    International Nuclear Information System (INIS)

    Cui, Lulu; Bi, Jiacheng; Yan, Dehong; Ye, Xiufeng; Zheng, Mingxing; Yu, Guang; Wan, Xiaochun

    2017-01-01

    IgE is a key effector molecule in atopic diseases; however, the regulation mechanisms of IgE production in IgE B cells remain poorly understood. In the present study, we demonstrate that JSI-124 (cucurbitacin I), a selective STAT3 inhibitor, selectively inhibits production of IgE by a human IgE B cell line, CRL-8033 cells, while does not affect the IgG production by IgG B cell lines. In the aspect of molecular mechanism, we found that Igλ, but not Ighe, gene expression was suppressed by JSI-124. The above effects of JSI-124 were not mediated by affecting cellular proliferation or apoptosis. Furthermore, multiple B cell differentiation-related genes expression was not significantly affected by JSI-124. Taken together, we demonstrate a potential strategy of therapeutically suppressing IgE production without affecting IgG production in atopic patients. - Highlights: • JSI-124 inhibits IgE production in an IgE B cell line, CRL-8033 cells. • JSI-124 does not affect IgG production by IgG B cell lines. • JSI-124 inhibits IgE production mainly by suppressing transcription of Igλ.

  16. Off-Line Testing of Tribo-Systems for Sheet Metal Forming Production

    DEFF Research Database (Denmark)

    Bay, Niels; Ceron, Ermanno

    2014-01-01

    Off-line testing of new tribo-systems for sheet metal forming production is an important issue, when new, environmentally benign lubricants are to be introduced. To obtain useful results it is, however, vital to ensure similar conditions as in the production process regarding the main tribo...... leading to very high tool/workpiece interface pressure and temperature in the second re-draw. Under such conditions only the best lubricant systems work satisfactory, and the paper shows how the performance of different tribo-systems in production may be predicted by off-line testing combined...

  17. Statistical analysis of probabilistic models of software product lines with quantitative constraints

    DEFF Research Database (Denmark)

    Beek, M.H. ter; Legay, A.; Lluch Lafuente, Alberto

    2015-01-01

    We investigate the suitability of statistical model checking for the analysis of probabilistic models of software product lines with complex quantitative constraints and advanced feature installation options. Such models are specified in the feature-oriented language QFLan, a rich process algebra...... of certain behaviour to the expected average cost of products. This is supported by a Maude implementation of QFLan, integrated with the SMT solver Z3 and the distributed statistical model checker MultiVeStA. Our approach is illustrated with a bikes product line case study....

  18. A Value-Based Business Approach to Product Line Software Engineering

    Directory of Open Access Journals (Sweden)

    Raman K. Agrawalla

    2009-08-01

    Full Text Available The present conceptual paper is an attempt to provide a Value-Based Business Approach (VBBA to product line software engineering. It argues that Product line software engineering should be seen as a system and considered as a means towards the end of appropriating more and more value for the business firm; contingent upon the fact that it provides value to customer and customer's customers operating its value creating system with agility, speed, economy and innovation; getting governed by the positive sum value creation outlook and guided by value- based management. With our value-based business triad, the product line engineering process can hope to achieve simultaneously value, variety and volume, product differentiation and cost leadership enabling the business firm to land on the virtuous value spiral.

  19. Advances in Mammalian Cell Line Development Technologies for Recombinant Protein Production

    Directory of Open Access Journals (Sweden)

    Say Kong Ng

    2013-04-01

    Full Text Available From 2006 to 2011, an average of 15 novel recombinant protein therapeutics have been approved by US Food and Drug Administration (FDA annually. In addition, the expiration of blockbuster biologics has also spurred the emergence of biosimilars. The increasing numbers of innovator biologic products and biosimilars have thus fuelled the demand of production cell lines with high productivity. Currently, mammalian cell line development technologies used by most biopharmaceutical companies are based on either the methotrexate (MTX amplification technology or the glutamine synthetase (GS system. With both systems, the cell clones obtained are highly heterogeneous, as a result of random genome integration by the gene of interest and the gene amplification process. Consequently, large numbers of cell clones have to be screened to identify rare stable high producer cell clones. As such, the cell line development process typically requires 6 to 12 months and is a time, capital and labour intensive process. This article reviews established advances in protein expression and clone screening which are the core technologies in mammalian cell line development. Advancements in these component technologies are vital to improve the speed and efficiency of generating robust and highly productive cell line for large scale production of protein therapeutics.

  20. The relationship of metabolic burden to productivity levels in CHO cell lines.

    Science.gov (United States)

    Zou, Wu; Edros, Raihana; Al-Rubeai, Mohamed

    2018-03-01

    The growing demand for recombinant therapeutics has driven biotechnologists to develop new production strategies. One such strategy for increasing the expression of heterologous proteins has focused on enhancing cell-specific productivity through environmental perturbations. In this work, the effects of hypothermia, hyperosmolarity, high shear stress, and sodium butyrate treatment on growth and productivity were studied using three (low, medium, and high producing) CHO cell lines that differed in their specific productivities of monoclonal antibody. In all three cell lines, the inhibitory effect of these parameters on proliferation was demonstrated. Additionally, compared to the control, specific productivity was enhanced under all conditions and exhibited a consistent cell line specific pattern, with maximum increases (50-290%) in the low producer, and minimum increases (7-20%) in the high producer. Thus, the high-producing cell line was less responsive to environmental perturbations than the low-producing cell line. We hypothesize that this difference is most likely due to the bottleneck associated with a higher metabolic burden caused by higher antibody expression. Increased recombinant mRNA levels and pyruvate carboxylase activities due to low temperature and hyperosmotic stress were found to be positively associated with the metabolic burden. © 2017 International Union of Biochemistry and Molecular Biology, Inc.

  1. Statistical Methods in Assembly Quality Management of Multi-Element Products on Automatic Rotor Lines

    Science.gov (United States)

    Pries, V. V.; Proskuriakov, N. E.

    2018-04-01

    To control the assembly quality of multi-element mass-produced products on automatic rotor lines, control methods with operational feedback are required. However, due to possible failures in the operation of the devices and systems of automatic rotor line, there is always a real probability of getting defective (incomplete) products into the output process stream. Therefore, a continuous sampling control of the products completeness, based on the use of statistical methods, remains an important element in managing the quality of assembly of multi-element mass products on automatic rotor lines. The feature of continuous sampling control of the multi-element products completeness in the assembly process is its breaking sort, which excludes the possibility of returning component parts after sampling control to the process stream and leads to a decrease in the actual productivity of the assembly equipment. Therefore, the use of statistical procedures for continuous sampling control of the multi-element products completeness when assembled on automatic rotor lines requires the use of such sampling plans that ensure a minimum size of control samples. Comparison of the values of the limit of the average output defect level for the continuous sampling plan (CSP) and for the automated continuous sampling plan (ACSP) shows the possibility of providing lower limit values for the average output defects level using the ACSP-1. Also, the average sample size when using the ACSP-1 plan is less than when using the CSP-1 plan. Thus, the application of statistical methods in the assembly quality management of multi-element products on automatic rotor lines, involving the use of proposed plans and methods for continuous selective control, will allow to automating sampling control procedures and the required level of quality of assembled products while minimizing sample size.

  2. The recommendation of line-balancing improvement on MCM product line 1 using genetics algorithm and moodie young at XYZ Company, Co.

    Science.gov (United States)

    Sriwana, I. K.; Marie, I. A.; Mangala, D.

    2017-12-01

    Kencana Gemilang, Co. is one electronics industry engaging in the manufacture sector. This company manufactures and assembles household electronic products, such as rice cooker, fan, iron, blender, etc. The company deals with an issue of underachievement of an established production target on MCM products line 1. This study aimed to calculate line efficiencies, delay times, and initial line smoothness indexes. The research was carried out by means of depicting a precedence diagram and gathering time data of each work element followed by examination and calculation of standard time as well as line balancing using methods of Moodie Young and Generics Algorithm. Based on results of calculation, better line balancing than the existing initial conditions, i.e. improvement in the line efficiency by 18.39%, deterioration in balanced delay by 28.39%, and deterioration of a smoothness index by 23.85% was obtained.

  3. Hospital Inspections

    Data.gov (United States)

    U.S. Department of Health & Human Services — Welcome to hospitalinspections.org, a website run by the Association of Health Care Journalists (AHCJ) that aims to make federal hospital inspection reports easier...

  4. Integration of a hydraulic production plant in a weak power system on a long radial line

    Energy Technology Data Exchange (ETDEWEB)

    Lariviere, P. [Hydro-Quebec TransEnergie, 5655 de Marseille, Montreal, Quebec (Canada); Racine, M. [Hydro-Quebec TransEnergie, C.P. 10 000, Montreal, Quebec (Canada)

    2009-03-15

    Integrating power plants on long lines and weak power systems requires some care. To this effect, a study was conducted to determine if severe disturbances could result when a hydraulic production plant is integrated along a very long radial transmission line. Frequency responses were evaluated to identify possible resonant system operating conditions. Many events such as faults, transformer energyzing and line opening were investigated. All power plant synchronous machines were represented including exciter and governor regulators. Impact of dynamic modeling of the load was examined. The study demonstrates that the overall protective strategy implemented will limit worst overvoltage constraints imposed to equipment and load within an acceptable level. (author)

  5. On-line monitoring of solar cell module production by ellipsometry technique

    International Nuclear Information System (INIS)

    Fried, M.

    2014-01-01

    Non-destructive analyzing tools are needed at all stages of thin film photovoltaic (PV) development, and on production lines. In thin film PV, layer thicknesses, micro-structure, composition, layer optical properties, and their uniformity (because each elementary cell is connected electrically in series within a big panel) serve as an important starting point in the evaluation of the performance of the cell or module. An important focus is to express the dielectric functions of each component material in terms of a handful of wavelength independent parameters whose variation can cover all process variants of that material. With the resulting database, spectroscopic ellipsometry coupled with multilayer analysis can be developed for on-line point-by-point mapping and on-line line-by-line imaging. This work tries to review the investigations of different types of PV-layers (anti-reflective coating, transparent-conductive oxide (TCO), multi-diode-structure, absorber and window layers) showing the existing dielectric function databases for the thin film components of CdTe, CuInGaSe 2 , thin Si, and TCO layers. Off-line point-by-point mapping can be effective for characterization of non-uniformities in full scale PV panels in developing labs but it is slow in the on-line mode when only 15 points can be obtained (within 1 min) as a 120 cm long panel moves by the mapping station. In the last years [M. Fried et al., Thin Solid Films 519, 2730 (2011)], instrumentation was developed that provides a line image of spectroscopic ellipsometry (wl = 350–1000 nm) data. Up to now a single 30 point line image can be collected in 10 s over a 15 cm width of PV material. This year we are building a 30 and a 60 cm width expanded beam ellipsometer the speed of which will be increased by 10 ×. Then 1800 points can be mapped in a 1 min traverse of a 60 ∗ 120 cm PV panel or flexible roll-to-roll substrate. - Highlights: • Instrumentation developed provides a line image of

  6. On-line monitoring of solar cell module production by ellipsometry technique

    Energy Technology Data Exchange (ETDEWEB)

    Fried, M., E-mail: fried@mfa.kfki.hu

    2014-11-28

    Non-destructive analyzing tools are needed at all stages of thin film photovoltaic (PV) development, and on production lines. In thin film PV, layer thicknesses, micro-structure, composition, layer optical properties, and their uniformity (because each elementary cell is connected electrically in series within a big panel) serve as an important starting point in the evaluation of the performance of the cell or module. An important focus is to express the dielectric functions of each component material in terms of a handful of wavelength independent parameters whose variation can cover all process variants of that material. With the resulting database, spectroscopic ellipsometry coupled with multilayer analysis can be developed for on-line point-by-point mapping and on-line line-by-line imaging. This work tries to review the investigations of different types of PV-layers (anti-reflective coating, transparent-conductive oxide (TCO), multi-diode-structure, absorber and window layers) showing the existing dielectric function databases for the thin film components of CdTe, CuInGaSe{sub 2}, thin Si, and TCO layers. Off-line point-by-point mapping can be effective for characterization of non-uniformities in full scale PV panels in developing labs but it is slow in the on-line mode when only 15 points can be obtained (within 1 min) as a 120 cm long panel moves by the mapping station. In the last years [M. Fried et al., Thin Solid Films 519, 2730 (2011)], instrumentation was developed that provides a line image of spectroscopic ellipsometry (wl = 350–1000 nm) data. Up to now a single 30 point line image can be collected in 10 s over a 15 cm width of PV material. This year we are building a 30 and a 60 cm width expanded beam ellipsometer the speed of which will be increased by 10 ×. Then 1800 points can be mapped in a 1 min traverse of a 60 ∗ 120 cm PV panel or flexible roll-to-roll substrate. - Highlights: • Instrumentation developed provides a line image of

  7. Modal Transition Systems as the Basis for Interface Theories and Product Lines

    DEFF Research Database (Denmark)

    Nyman, Ulrik

    and a subset of modal transition systems is proved. The developed interface theory, which can describe liveness properties, is also applied as a behavioral variability theory for product line development. The two last papers of the thesis concern themselves with modal and mixed transition systems. The first....... It also proves PSPACE-hardness for consistency of mixed specifications and establishes a number of reductions between the different decision problems. Keywords: Modeling, Software Product Lines, Embedded Software, Modal Refinement, Labeled Transition Systems, Modal Transition Systems, Mixed Transition......This thesis presents research taking its outset in component-based software development, interface theory and software product lines, as well as modeling formalisms for describing component based software systems and their interfaces. The main part of the thesis consists of five papers. The first...

  8. Open Wilson lines and generalized star product in noncommutative scalar field theories

    International Nuclear Information System (INIS)

    Kiem, Youngjai; Sato, Haru-Tada; Rey, Soo-Jong; Yee, Jung-Tay

    2002-01-01

    Open Wilson line operators and a generalized star product have been studied extensively in noncommutative gauge theories. We show that they also show up in noncommutative scalar field theories as universal structures. We first point out that the dipole picture of noncommutative geometry provides an intuitive argument for the robustness of the open Wilson lines and generalized star products therein. We calculate the one-loop effective action of noncommutative scalar field theory with a cubic self-interaction and show explicitly that the generalized star products arise in the nonplanar part. It is shown that, at the low-energy, large noncommutativity limit, the nonplanar part is expressible solely in terms of the scalar open Wilson line operator and descendants

  9. Reengineering a PC-based System into the Mobile Device Product Line

    DEFF Research Database (Denmark)

    Zhang, Weishan; Jarzabek, Stanislaw; Loughran, Neil

    2003-01-01

    There is a growing demand to port existing PC-based software systems to mobile device platforms. Systems running on mobile devices share basic characteristics with their PC-based counterparts, but differ from them in details of user interfaces, application models, etc. Systems running on mobile...... devices must also perform well using less memory than PC-based systems. Mobile devices themselves are different from each other in many ways, too. We describe how we made an existing PC-based City Guide System available on a wide range of mobile devices, in a cost-effective way. We applied "reengineering...... into a product line architecture" approach to achieve the goal. Our product line architecture facilitates reuse via generation. We generate specific City Guide Systems for target platforms including PC, Pocket PC and other mobile devices, from generic meta-components that form the City Guide System product line...

  10. Advantages and Disadvantages of Possible Methods of Managing the Production on the Assembly Lines in the Given Company

    OpenAIRE

    Václavková, Eva

    2014-01-01

    The bachelor thesis deals with methods of lean management, more exactly production planning and managing the production lines assembly. In this thesis, production planning system, kanban cards and heijunka will be described. The aim of this thesis is to describe methods of managing the production lines assembly and to suggest more effective management.

  11. A regression-based Kansei engineering system based on form feature lines for product form design

    Directory of Open Access Journals (Sweden)

    Yan Xiong

    2016-06-01

    Full Text Available When developing new products, it is important for a designer to understand users’ perceptions and develop product form with the corresponding perceptions. In order to establish the mapping between users’ perceptions and product design features effectively, in this study, we presented a regression-based Kansei engineering system based on form feature lines for product form design. First according to the characteristics of design concept representation, product form features–product form feature lines were defined. Second, Kansei words were chosen to describe image perceptions toward product samples. Then, multiple linear regression and support vector regression were used to construct the models, respectively, that predicted users’ image perceptions. Using mobile phones as experimental samples, Kansei prediction models were established based on the front view form feature lines of the samples. From the experimental results, these two predict models were of good adaptability. But in contrast to multiple linear regression, the predict performance of support vector regression model was better, and support vector regression is more suitable for form regression prediction. The results of the case showed that the proposed method provided an effective means for designers to manipulate product features as a whole, and it can optimize Kansei model and improve practical values.

  12. Marketing plan for Pharmacare product line in the Moscow region Case Oriola-KD

    OpenAIRE

    Mashkilleyson, Peter

    2012-01-01

    The thesis was commissioned by Oriola-KD. It deals with a marketing plan for a product line called Pharmacare. The product line will be launched in 2012 in the Moscow region in the Russian Federation. The purpose of this thesis was to acquire useful information about the Moscow market for the target company and produce a marketing plan that they can implement. The research question was how to create an effective marketing plan and what it entails. The literary review consisted of the theo...

  13. Products of Snowflaked Euclidean Lines Are Not Minimal for Looking Down

    Directory of Open Access Journals (Sweden)

    Joseph Matthieu

    2017-11-01

    Full Text Available We show that products of snowflaked Euclidean lines are not minimal for looking down. This question was raised in Fractured fractals and broken dreams, Problem 11.17, by David and Semmes. The proof uses arguments developed by Le Donne, Li and Rajala to prove that the Heisenberg group is not minimal for looking down. By a method of shortcuts, we define a new distance d such that the product of snowflaked Euclidean lines looks down on (RN , d, but not vice versa.

  14. Development of at-line assay to monitor charge variants of MAbs during production.

    Science.gov (United States)

    St Amand, M M; Ogunnaike, B A; Robinson, A S

    2014-01-01

    One major challenge currently facing the biopharmaceutical industry is to understand how MAb microheterogeneity affects therapeutic efficacy, potency, immunogenicity, and clearance. MAb micro-heterogeneity can result from post-translational modifications such as sialylation, galactosylation, C-terminal lysine cleavage, glycine amidation, and tryptophan oxidation, each of which can generate MAb charge variants; such heterogeneity can affect pharmacokinetics (PK) considerably. Implementation of appropriate on-line quality control strategies may help to regulate bioprocesses, thus enabling more homogenous material with desired post-translational modifications and PK behavior. However, one major restriction to implementation of quality control strategies is the availability of techniques for obtaining on-line or at-line measurements of these attributes. In this work, we describe the development of an at-line assay to separate MAb charge variants in near real-time, which could ultimately be used to implement on-line quality control strategies for MAb production. The assay consists of a 2D-HPLC method with sequential in-line Protein A and WCX-10 HPLC column steps. To perform the 2D-HPLC assay at-line, the two columns steps were integrated into a single method using a novel system configuration that allowed parallel flow over column 1 or column 2 or sequential flow from column 1 to column 2. A bioreactor system was also developed such that media samples could be removed automatically from bioreactor vessels during production and delivered to the 2D-HPLC for analysis. With this at-line HPLC assay, we have demonstrated that MAb microheterogeneity occurs throughout the cell cycle whether the host cell line is grown under different or the same nominal culture conditions. © 2013 American Institute of Chemical Engineers.

  15. Production layout improvement by using line balancing and Systematic Layout Planning (SLP) at PT. XYZ

    Science.gov (United States)

    Buchari; Tarigan, U.; Ambarita, M. B.

    2018-02-01

    PT. XYZ is a wood processing company which produce semi-finished wood with production system is make to order. In the production process, it can be seen that the production line is not balanced. The imbalance of the production line is caused by the difference in cycle time between work stations. In addition, there are other issues, namely the existence of material flow pattern is irregular so it resulted in the backtracking and displacement distance away. This study aimed to obtain the allocation of work elements to specific work stations and propose an improvement of the production layout based on the result of improvements in the line balancing. The method used in the balancing is Ranked Positional Weight (RPW) or also known as Helgeson Birnie method. While the methods used in the improvement of the layout is the method of Systematic Layout Planning (SLP). By using Ranked Positional Weight (RPW) obtained increase in line efficiency becomes 84,86% and decreased balance delay becomes 15,14%. Repairing the layout using the method of Systematic Layout Planning (SLP) also give good results with a reduction in path length becomes 133,82 meters from 213,09 meters previously or a decrease of 37.2%.

  16. Study on Product Lines for Digital Information Products%数字信息产品生产线研究

    Institute of Scientific and Technical Information of China (English)

    毛凌翔; 程慧平

    2014-01-01

    在数字信息逐渐从“资源观”向“产品观”转换的背景下,从数字信息产品的角度分析数字信息产品生产过程与模型,提出基于人工构件变异和组件重用的数字信息产品生产线理论,并应用于地理信息产品中进行实证,有望提高数字信息产品的生产效率并节约生产成本。%With the development of digital information technology and market-driven economy, user needs become diversified and customized today, and digital information is increasingly turning toward product-perspective direction from the resource-perspective. From the perspective of digital information products, digital information production process and model has been analyzed, and a digital information product lines theory based on artifacts variation and component reuse has been proposed. Then using instance to prove the correctness of the theory, practical use of digital information production line mode can greatly improve production efficiency of digital information products and significantly save production costs.

  17. User interface inspection methods a user-centered design method

    CERN Document Server

    Wilson, Chauncey

    2014-01-01

    User Interface Inspection Methods succinctly covers five inspection methods: heuristic evaluation, perspective-based user interface inspection, cognitive walkthrough, pluralistic walkthrough, and formal usability inspections. Heuristic evaluation is perhaps the best-known inspection method, requiring a group of evaluators to review a product against a set of general principles. The perspective-based user interface inspection is based on the principle that different perspectives will find different problems in a user interface. In the related persona-based inspection, colleagues assume the

  18. Physiological response and productivity of safflower lines under water deficit and rehydration.

    Science.gov (United States)

    Bortolheiro, Fernanda P A P; Silva, Marcelo A

    2017-01-01

    Water deficit is one of the major stresses affecting plant growth and productivity worldwide. Plants induce various morphological, physiological, biochemical and molecular changes to adapt to the changing environment. Safflower (Carthamus tinctorius L.), a potential oil producer, is highly adaptable to various environmental conditions, such as lack of rainfall and temperatures. The objective of this work was to study the physiological and production characteristics of six safflower lines in response to water deficit followed by rehydration. The experiment was conducted in a protected environment and consisted of 30 days of water deficit followed by 18 days of rehydration. A differential response in terms of photosynthetic pigments, electrolyte leakage, water potential, relative water content, grain yield, oil content, oil yield and water use efficiency was observed in the six lines under water stress. Lines IMA 04, IMA 10, IMA 14 showed physiological characteristics of drought tolerance, with IMA 14 and IMA 16 being the most productive after water deficit. IMA 02 and IMA 21 lines displayed intermediate characteristics of drought tolerance. It was concluded that the lines responded differently to water deficit stress, showing considerable genetic variation and influence to the environment.

  19. Physiological response and productivity of safflower lines under water deficit and rehydration

    Directory of Open Access Journals (Sweden)

    FERNANDA P.A.P. BORTOLHEIRO

    2017-12-01

    Full Text Available ABSTRACT Water deficit is one of the major stresses affecting plant growth and productivity worldwide. Plants induce various morphological, physiological, biochemical and molecular changes to adapt to the changing environment. Safflower (Carthamus tinctorius L., a potential oil producer, is highly adaptable to various environmental conditions, such as lack of rainfall and temperatures. The objective of this work was to study the physiological and production characteristics of six safflower lines in response to water deficit followed by rehydration. The experiment was conducted in a protected environment and consisted of 30 days of water deficit followed by 18 days of rehydration. A differential response in terms of photosynthetic pigments, electrolyte leakage, water potential, relative water content, grain yield, oil content, oil yield and water use efficiency was observed in the six lines under water stress. Lines IMA 04, IMA 10, IMA 14 showed physiological characteristics of drought tolerance, with IMA 14 and IMA 16 being the most productive after water deficit. IMA 02 and IMA 21 lines displayed intermediate characteristics of drought tolerance. It was concluded that the lines responded differently to water deficit stress, showing considerable genetic variation and influence to the environment.

  20. Spontaneous pyrogen production by mouse histiocytic and myelomonocytic tumor cell lines in vitro.

    Science.gov (United States)

    Bodel, P

    1978-05-01

    Tumor-associated fever occurs commonly in acute leukemias and lymphomas. We investigated the capacity for in vitro production of pyrogen by three mouse histiocytic lymphoma cell lines (J-774, PU5-1.8, p 388 D1), one myelomonoyctic line (WEHI-3), and tow lymphoma-derived lines, RAW-8 and R-8. Pyrogen was released spontaneously into the culture medium during growth by all cell lines with macrophage or myeloid characteristics including lysozyme production; R-8 cells, of presumed B-lymphocyte origin, did not produce pyrogen. When injected into mice, the pyrogens gave fever curves typical of endogenous pyrogen, were inactived by heating to 56 degrees C and by pronase digestion, and appeared to be secreted continuously by viable cells. Two pyrogenic molecular species produced by H-774 cells were identified by Sephadex filtration, one of mol wt approximately equal to 30,000, and the other greater than or equal to 60,000. By contrast, three carcinoma cell lines of human origin and SV-40 3T3 mouse fibroblasts did not produce pyrogen in vitro. These results suggest that some malignant cells derived from phagocytic cells of bone marrow origin retain their capacity for pyrogen production, and may spontaneously secrete pyrogen during growth.

  1. AN INVESTIGATION OF THE APPLICABILITY OF SOFTWARE PRODUCT LINE ENGINEERING FOR ENERGY AND COST-EFFICIENT GREENHOUSE PRODUCTION

    DEFF Research Database (Denmark)

    Mærsk-Møller, Hans Martin

    product line architecture, and how the variability is managed and described using SPLE. It also describes how the DynaLight software product line and its products were developed. Doing so, it shows utilization of rich client platform technology in conjunction with SPLE, which has not been described....... Supplementary lighting is utilized to compensate for the light conditions in the darker months of the year in order to grow certain plants. This is both energy consuming and expensive, as the cost of electricity is high. New knowledge on the plasticity in plants to irregular light patterns is basis for a novel...... and cost, and two desktop tools, the first, DynaLight Desktop, a day-ahead-light-planning tool, and the second, DynaLight Desktop w/control, with the added capability to execute the plans by actuating the light inside the greenhouses. This work provides a SPLE methodology explicitly customized to our...

  2. Methionine sulfoximine supplementation enhances productivity in GS-CHOK1SV cell lines through glutathione biosynthesis.

    Science.gov (United States)

    Feary, Marc; Racher, Andrew J; Young, Robert J; Smales, C Mark

    2017-01-01

    In Lonza Biologics' GS Gene Expression System™, recombinant protein-producing GS-CHOK1SV cell lines are generated by transfection with an expression vector encoding both GS and the protein product genes followed by selection in MSX and glutamine-free medium. MSX is required to inhibit endogenous CHOK1SV GS, and in effect create a glutamine auxotrophy in the host that can be complemented by the expression vector encoded GS in selected cell lines. However, MSX is not a specific inhibitor of GS as it also inhibits the activity of GCL (a key enzyme in the glutathione biosynthesis pathway) to a similar extent. Glutathione species (GSH and GSSG) have been shown to provide both oxidizing and reducing equivalents to ER-resident oxidoreductases, raising the possibility that selection for transfectants with increased GCL expression could result in the isolation of GS-CHOKISV cell lines with improved capacity for recombinant protein production. In this study we have begun to address the relationship between MSX supplementation, the amount of intracellular GCL subunit and mAb production from a panel of GS-CHOK1SV cell lines. We then evaluated the influence of reduced GCL activity on batch culture of an industrially relevant mAb-producing GS-CHOK1SV cell line. To the best of our knowledge, this paper describes for the first time the change in expression of GCL subunits and recombinant mAb production in these cell lines with the degree of MSX supplementation in routine subculture. Our data also shows that partial inhibition of GCL activity in medium containing 75 µM MSX increases mAb productivity, and its more specific inhibitor BSO used at a concentration of 80 µM in medium increases the specific rate of mAb production eight-fold and the concentration in harvest medium by two-fold. These findings support a link between the inhibition of glutathione biosynthesis and recombinant protein production in industrially relevant systems and provide a process-driven method for

  3. Health risks related to illegal and on-line sale of drugs and food supplements: results of a survey on marketed products in Italy from 2011 to 2013.

    Science.gov (United States)

    Gaudiano, Maria Cristina; Manna, Livia; Bartolomei, Monica; Rodomonte, Andrea Luca; Bertocchi, Paola; Antoniella, Eleonora; Romanini, Laura; Alimonti, Stefano; Rufini, Leandro; Valvo, Luisa

    2016-01-01

    The increasing illegal and on-line market of medicines and food supplements is helping the widespread diffusion of harmful counterfeit and forbidden products among consumers of developed countries. The objectives of this survey were the description of the main frauds recognized by public officers and the detection of illegal or counterfeit drugs and food supplements. Medicines and food supplements found by Police forces on the illegal market or resulting from seizures made by Italian Customs authorities were visually inspected and analysed to evaluate their quality and the presence of other undeclared substances. The visual inspection and the chemical analysis revealed unsuitable packaging (mostly lacking of adequate information for consumers), absence of the declared active substances and presence of undeclared active substances. Products containing doping agents, illegal substances and active ingredients requiring medical supervision were found. The present work confirmed the health risk associated with assumption of medicines purchased on the Internet and from the illegal supply chain and evidenced a new threat to consumer safety related to the presence of pharmaceutical active ingredients in food supplements claiming to contain only "natural ingredients".

  4. Bottom-Up Technologies for Reuse: Automated Extractive Adoption of Software Product Lines

    OpenAIRE

    Martinez , Jabier ,; Ziadi , Tewfik; Bissyandé , Tegawendé; Klein , Jacques ,; Le Traon , Yves ,

    2017-01-01

    International audience; Adopting Software Product Line (SPL) engineering principles demands a high up-front investment. Bottom-Up Technologies for Reuse (BUT4Reuse) is a generic and extensible tool aimed to leverage existing similar software products in order to help in extractive SPL adoption. The envisioned users are 1) SPL adopters and 2) Integrators of techniques and algorithms to provide automation in SPL adoption activities. We present the methodology it implies for both types of users ...

  5. Base Stock Policy in a Join-Type Production Line with Advanced Demand Information

    Science.gov (United States)

    Hiraiwa, Mikihiko; Tsubouchi, Satoshi; Nakade, Koichi

    Production control such as the base stock policy, the kanban policy and the constant work-in-process policy in a serial production line has been studied by many researchers. Production lines, however, usually have fork-type, join-type or network-type figures. In addition, in most previous studies on production control, a finished product is required at the same time as arrival of demand at the system. Demand information is, however, informed before due date in practice. In this paper a join-type (assembly) production line under base stock control with advanced demand information in discrete time is analyzed. The recursive equations for the work-in-process are derived. The heuristic algorithm for finding appropriate base stock levels of all machines at short time is proposed and the effect of advanced demand information is examined by simulation with the proposed algorithm. It is shown that the inventory cost can decreases with little backlogs by using the appropriate amount of demand information and setting appropriate base stock levels.

  6. Modeling of Throughput in Production Lines Using Response Surface Methodology and Artificial Neural Networks

    Directory of Open Access Journals (Sweden)

    Federico Nuñez-Piña

    2018-01-01

    Full Text Available The problem of assigning buffers in a production line to obtain an optimum production rate is a combinatorial problem of type NP-Hard and it is known as Buffer Allocation Problem. It is of great importance for designers of production systems due to the costs involved in terms of space requirements. In this work, the relationship among the number of buffer slots, the number of work stations, and the production rate is studied. Response surface methodology and artificial neural network were used to develop predictive models to find optimal throughput values. 360 production rate values for different number of buffer slots and workstations were used to obtain a fourth-order mathematical model and four hidden layers’ artificial neural network. Both models have a good performance in predicting the throughput, although the artificial neural network model shows a better fit (R=1.0000 against the response surface methodology (R=0.9996. Moreover, the artificial neural network produces better predictions for data not utilized in the models construction. Finally, this study can be used as a guide to forecast the maximum or near maximum throughput of production lines taking into account the buffer size and the number of machines in the line.

  7. Disregarded use of herbal medical products and dietary supplements among surgical and medical patients as estimated by home inspection and interview

    DEFF Research Database (Denmark)

    Glintborg, Bente; Andersen, Stig Ejdrup; Spang-Hanssen, Eva

    2005-01-01

    and DS among patients recently discharged from two hospital departments. METHODS: Patients were visited within 1 week after discharge and interviewed about their use of HMP and DS. Stored products were inspected and registered. Hospital files and discharge letters were examined to establish the frequency...... of registration. RESULTS: Totally, 83 surgical and 117 medical patients were included (n = 200), 139 patients (70%) were women. 53 patients (27%) stored no HMP or DS, whereas the home inventories of 147 patients (74%) comprised 343 products. 116 patients (58%) used HMP or DS daily and 25 patients (13%) used...

  8. Quantitative Analysis of Probabilistic Models of Software Product Lines with Statistical Model Checking

    DEFF Research Database (Denmark)

    ter Beek, Maurice H.; Legay, Axel; Lluch Lafuente, Alberto

    2015-01-01

    We investigate the suitability of statistical model checking techniques for analysing quantitative properties of software product line models with probabilistic aspects. For this purpose, we enrich the feature-oriented language FLAN with action rates, which specify the likelihood of exhibiting pa...

  9. Reliability Analysis of an Extended Shock Model and Its Optimization Application in a Production Line

    Directory of Open Access Journals (Sweden)

    Renbin Liu

    2014-01-01

    some important reliability indices are derived, such as availability, failure frequency, mean vacation period, mean renewal cycle, mean startup period, and replacement frequency. Finally, a production line controlled by two cold-standby computers is modeled to present numerical illustration and its optimal part-time job policy at a maximum profit.

  10. An analysis of unit tests of a flight software product line

    NARCIS (Netherlands)

    Ganesan, D.; Lindvall, M.; McComas, D.; Bartholomew, M.; Slegel, S.; Medina, B.; Krikhaar, R.; Verhoef, C.; Dharmalingam, G.; Montgomery, L.P.

    2013-01-01

    This paper presents an analysis of the unit testing approach developed and used by the Core Flight Software System (CFS) product line team at the NASA Goddard Space Flight Center (GSFC). The goal of the analysis is to understand, review, and recommend strategies for improving the CFS' existing unit

  11. The degradation of lining of rotary furnaces in the production of zinc oxide

    Czech Academy of Sciences Publication Activity Database

    Luptáková, Natália; Pešlová, F.; Anisimov, E.

    2014-01-01

    Roč. 21, č. 3 (2014), s. 116-121 ISSN 1335-0803 Institutional support: RVO:68081723 Keywords : zinc oxide * the production of zinc oxide * zinc slag * refractories * the degradation of rotary furnace linings Subject RIV: JG - Metallurgy http://ojs.mateng.sk/index.php/Mateng/article/view/133/194

  12. Feasibility of evaluating possible 85Kr environmental contamination from neon lamp production line to be installed

    International Nuclear Information System (INIS)

    Li Guangzuo

    1989-01-01

    Using a simplified method, the concentrations of 85 Kr leaking into the air of a workshop and its surroundings, where a neon lamp production line was to be installed, were calculated. The doses to the workers and inhabitants nearby were also estimated. Thus, the evaluation of 85 Kr enviromental contamination caused by imported equipments was made feasible

  13. CONSTRAINING JET PRODUCTION SCENARIOS BY STUDIES OF NARROW-LINE RADIO GALAXIES

    Energy Technology Data Exchange (ETDEWEB)

    Sikora, Marek [Nicolaus Copernicus Astronomical Center, Bartycka 18, 00-716 Warsaw (Poland); Stasinska, Grazyna [LUTH, Observatoire de Paris, CNRS, Universite Paris Diderot, Place Jules Janssen, F-92190 Meudon (France); Koziel-Wierzbowska, Dorota [Astronomical Observatory, Jagiellonian University, ul. Orla 171, 30-244 Krakow (Poland); Madejski, Greg M. [Kavli Institute for Particle Astrophysics and Cosmology, Stanford University, Stanford, CA 94305 (United States); Asari, Natalia V., E-mail: sikora@camk.edu.pl [Institute of Astronomy, University of Cambridge, Madingley Road, Cambridge CB3 0HA (United Kingdom)

    2013-03-01

    We study a large sample of narrow-line radio galaxies (NLRGs) with extended radio structures. Using 1.4 GHz radio luminosities L {sub 1.4}, narrow optical emission line luminosities L {sub [OIII]} and L{sub H{sub {alpha}}}, as well as black hole masses M {sub BH} derived from stellar velocity dispersions measured from the optical spectra obtained with the Sloan Digital Sky Survey, we find that (1) NLRGs cover about four decades of the Eddington ratio, {lambda} {identical_to} L {sub bol}/L {sub Edd}{proportional_to}L {sub line}/M {sub BH}; (2) L {sub 1.4}/M {sub BH} strongly correlates with {lambda}; and (3) radio loudness, R{identical_to}L{sub 1.4}/L{sub line}, strongly anti-correlates with {lambda}. A very broad range of the Eddington ratio indicates that the parent population of NLRGs includes both radio-loud quasars (RLQs) and broad-line radio galaxies (BLRGs). The correlations they obey and their high jet production efficiencies favor a jet production model which involves the so-called magnetically choked accretion scenario. In this model, production of the jet is dominated by the Blandford-Znajek mechanism, and the magnetic fields in the vicinity of the central black hole are confined by the ram pressure of the accretion flow. Since large net magnetic flux accumulated in central regions of the accretion flow required by the model can take place only via geometrically thick accretion, we speculate that the massive, 'cold' accretion events associated with luminous emission-line active galactic nucleus can be accompanied by an efficient jet production only if preceded by a hot, very sub-Eddington accretion phase.

  14. 46 CFR 502.206 - Production of documents and things and entry upon land for inspection and other purposes.

    Science.gov (United States)

    2010-10-01

    ... GENERAL AND ADMINISTRATIVE PROVISIONS RULES OF PRACTICE AND PROCEDURE Depositions, Written Interrogatories... inspect and copy any designated documents (including writings, drawings, graphs, charts, photographs... of § 502.203(a) and which are in the possession, custody or control of the party upon whom the...

  15. Enterprise logic vs product logic: the development of GE’s computer product line

    OpenAIRE

    Gandy, Anthony; Edwards, Roy

    2017-01-01

    The following article focuses on corporate strategies at General Electric (GE) and how corporate-level interventions impacted the market performance of the firm’s general purpose commercial mainframe product set in the period 1960–1968. We show that in periods of both divisional independent planning and corporate-level planning strategic governance, central decisions interfered in the execution of GE’s product strategy. GE’s institutional ‘enterprise logic’ negatively impacted the ‘product lo...

  16. Operational inspections

    International Nuclear Information System (INIS)

    Bystersky, M.

    1997-01-01

    Special equipment is described, designed for inspection of reactor pressure vessels performed from the inside. Central shaft manipulator ZMM-5 is available for crack detection control using ultrasound and eddy currents, for visual check of surfaces, repair works at the reactor pressure vessel, and hardness measurements. The manipulator consists of the manipulator bridge, a cable container, shaft segments, a control mechanism and auxiliary parts. Eight inspections were performed at the Bohunice nuclear power plant and two at the Paks nuclear power plant. (M.D.)

  17. 9 CFR 307.5 - Overtime and holiday inspection service.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Overtime and holiday inspection... INSPECTION AND CERTIFICATION FACILITIES FOR INSPECTION § 307.5 Overtime and holiday inspection service. (a..., at the rate specified in § 391.3, for the cost of the inspection service furnished on any holiday as...

  18. 40 CFR 1051.305 - How must I prepare and test my production-line vehicles or engines?

    Science.gov (United States)

    2010-07-01

    ... production-line vehicles or engines? 1051.305 Section 1051.305 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM RECREATIONAL ENGINES AND VEHICLES Testing Production-Line Vehicles and Engines § 1051.305 How must I prepare and test my production...

  19. 9 CFR 355.3 - Plants eligible for inspection.

    Science.gov (United States)

    2010-01-01

    ... INSPECTION AND CERTIFICATION CERTIFIED PRODUCTS FOR DOGS, CATS, AND OTHER CARNIVORA; INSPECTION... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Plants eligible for inspection. 355.3 Section 355.3 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

  20. 9 CFR 355.7 - Inauguration of inspection.

    Science.gov (United States)

    2010-01-01

    ... INSPECTION AND CERTIFICATION CERTIFIED PRODUCTS FOR DOGS, CATS, AND OTHER CARNIVORA; INSPECTION... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Inauguration of inspection. 355.7 Section 355.7 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

  1. Experience on inspection at PFPF

    International Nuclear Information System (INIS)

    Aoki, I.; Yamamoto, Y.; Takahashi, Saburo; Ooshima, Hirofumi; Kuniyasu, Kazufusa.

    1993-01-01

    In order to reduce a personal radiation exposure, Plutonium Fuel Production Facility (PFPF) introduced an automated MOX fabrication technology. Safeguards system for the PFPF was designed and installed so as to be compatible with automated process operation as much as possible. Introduction of these system in PFPF made possible to do the inspection measurements with unattended mode and Near Real Time Material Accountancy (NRTA), consequently inspection has been carrying out effectively and efficiently. This paper describes the new Inspection activities as a comparison with old Inspection activities based on our experience. (author)

  2. Obstacle detection method, obstacle removing method, device and production line for practicing the methods

    International Nuclear Information System (INIS)

    Yoneyama, Takao; Ishimatsu, Tsuneo; Komata, Hisashi; Suzuki, Keisaburo.

    1997-01-01

    The present invention provides techniques for detecting and removing obstacles, which can be applied to pipelines and vessels to be used in structures such as nuclear power structures and electric power generation facilities. Namely, when the pipelines or vessels are in any of the stages, namely, production, installation, before the use after installation and before the reuse after inspection, obstacles remaining in the pipelines and vessels are blown off by using a fluid jetting mechanism (air compressor). Elastic waves generated when the blown off obstacles abut against the pipelines and vessels are detected by using a sensor. As a result, the remaining obstacles can be detected during any one of the stages described above. The blowing is repeated till the absence of the obstacles is confirmed by elastic wave signals detected by the sensor. As a result, the remaining obstacles can be removed. (I.S.)

  3. USING DEMATEL-ANP INTEGRATED APPROACH FOR DECIDING PRODUCTION STRATEGY FOR A PRODUCTION LINE

    Directory of Open Access Journals (Sweden)

    Sinan APAK

    2017-09-01

    Full Text Available Production planning includes push, pull and hybrid production systems that production firms determine their production strategies according to many variables before starting production. The administration of this process requires experience and time. The intensity of rivalry makes this kind of decision processes important, because no firm has the luxury to waste time and to make a wrong decision. In order to solve this problem, research proposes to use integrated decision-making trial and evaluation laboratory (DEMATEL and analytic network process (ANP together which are methods of multi-criteria decision-making models. The process being used to establish which options are found to be most acceptable for operations managers has been demonstrated how applicable it is by using the generated model in automotive industry.

  4. ANALYSIS AND IMPROVEMENT OF PRODUCTION EFFICIENCY IN A CONSTRUCTION MACHINE ASSEMBLY LINE

    Directory of Open Access Journals (Sweden)

    Alidiane Xavier

    2016-07-01

    Full Text Available The increased competitiveness in the market encourages the ongoing development of systems and production processes. The aim is to increase production efficiency to production costs and waste be reduced to the extreme, allowing an increased product competitiveness. The objective of this study was to analyze the overall results of implementing a Kaizen philosophy in an automaker of construction machinery, using the methodology of action research, which will be studied in situ the macro production process from receipt of parts into the end of the assembly line , prioritizing the analysis time of shipping and handling. The results show that the continuous improvement activities directly impact the elimination of waste from the assembly process, mainly related to shipping and handling, improving production efficiency by 30% in the studied processes.

  5. A Broad Coverage Neutron Source For Security Inspections

    Science.gov (United States)

    Yang, Yang; Robert, Stubbers; Linchun, Wu; George, Miley

    2004-05-01

    To meet the increasing demanding requirements for security safety inspections, a line-type neutron source employing a cylindrical IEC (RC-IEC) is proposed for non-destructive "in situ" security inspections. The advantages of such a neutron source include line geometry, modularity, swithcability, variable source strength, low cost with minimum maintenance. Detailed description of a 1/3 scale cylindrical device is presented, which might demonstrate that a reasonably long RC-IEC produces a stable discharge with reasonably uniform neutron production along the cylindrical axis. Aiming at the neutron production efficiency at the order of 106 n/J, several methods to maximize neutron production efficiency are discussed. The results of a two-dimensional computer code(MCP) using a Monte Carlo numerical approach for the RC-IEC device are presented together with an analysis of neutron yield vs. different operation parameters.

  6. The Influence of Physical Fatigue on Work on a Production Line

    Directory of Open Access Journals (Sweden)

    Kołodziej Sabina

    2017-09-01

    Full Text Available The purpose of this study is to determine the factors having impacts on the physical fatigue of employees and to analyse its influence on work on a production line. In order to carry out these objectives, a comprehensive research was conducted in a medium enterprise producing processed fruit and vegetable products. Air temperature and humidity tests, employee survey, production line productivity measurements, and other observations were performed. Large variations in temperature and humidity were observed during the analysed period. Analysing the survey results, attention was paid to the declared length of sleeping of employees after each shift, the time when they feel fatigue and the factors that, according to respondents, have the greatest impact on the work performed. Attempts were made to determine the wellbeing of employees and to indicate the disturbing symptoms. Special attention was paid to the negative phenomena felt by respondents. The main factors affecting the physical fatigue of employees were identified and described. We sought to explain the impacts of physical fatigue on work on the production line. Improvements, which should help to reduce fatigue and improve working conditions, have been proposed. The analysis provided interesting information that could be used in various food manufacturing companies.

  7. A SOFTWARE PRODUCT LINE FOR ENERGY-EFFICIENT CONTROL OF SUPPLEMENTARY LIGHTING IN GREENHOUSES

    DEFF Research Database (Denmark)

    Mærsk-Møller, Hans Martin; Jørgensen, Bo Nørregaard

    2011-01-01

    of 2009 – 2010 showed 25 percent savings with no negative effect on plant quality. To accelerate the impact of our approach, we chose to use Software Product Line Engineering, as it enables a greater variety of related software tools to be created faster. We have created a web-based analysis tool, Dyna...... preserving production quality. This paper presents a novel approach addressing this issue. We use weather forecasts and electricity prices to compute cost- and energy-efficient supplementary light plans that achieve the required plant growth defined by the grower. Experiments performed during the winter...... of these two tools is described together with the lessons learned from using Software Product Line Engineering in the domain of greenhouse software development....

  8. Top-Down and Bottom-Up Approach for Model-Based Testing of Product Lines

    Directory of Open Access Journals (Sweden)

    Stephan Weißleder

    2013-03-01

    Full Text Available Systems tend to become more and more complex. This has a direct impact on system engineering processes. Two of the most important phases in these processes are requirements engineering and quality assurance. Two significant complexity drivers located in these phases are the growing number of product variants that have to be integrated into the requirements engineering and the ever growing effort for manual test design. There are modeling techniques to deal with both complexity drivers like, e.g., feature modeling and model-based test design. Their combination, however, has been seldom the focus of investigation. In this paper, we present two approaches to combine feature modeling and model-based testing as an efficient quality assurance technique for product lines. We present the corresponding difficulties and approaches to overcome them. All explanations are supported by an example of an online shop product line.

  9. Source term analysis for a criticality accident in metal production line glove boxes

    International Nuclear Information System (INIS)

    Nguyen, D.H.

    1991-06-01

    A recent development in criticality accident analysis is the deterministic calculations of the transport of fission products and actinides through the barriers of the physical facility. The knowledge of the redistribution of the materials inside the facility will help determine the reentry and clean-up procedures. The amount of radioactive materials released to the environment is the source term for dispersion calculations. We have used an integrated computer model to determine the release of fission products to the environment from a hypothetical criticality event in a glove box of the metal production line (MPL) at the Lawrence Livermore National Laboratory (LLNL)

  10. Production of higher quality bio-oils by in-line esterification of pyrolysis vapor

    Science.gov (United States)

    Hilten, Roger Norris; Das, Keshav; Kastner, James R; Bibens, Brian P

    2014-12-02

    The disclosure encompasses in-line reactive condensation processes via vapor phase esterification of bio-oil to decease reactive species concentration and water content in the oily phase of a two-phase oil, thereby increasing storage stability and heating value. Esterification of the bio-oil vapor occurs via the vapor phase contact and subsequent reaction of organic acids with ethanol during condensation results in the production of water and esters. The pyrolysis oil product can have an increased ester content and an increased stability when compared to a condensed pyrolysis oil product not treated with an atomized alcohol.

  11. Modified Starch of Sorghum Mutant Line Zh-30 For High Fiber Muffin Products

    International Nuclear Information System (INIS)

    Santosa, D. D. S; Human, S

    2009-01-01

    Sorghum mutant line Zh-30 is a breeding line developed at the Center for the Application of Isotope and Radiation Technology, BATAN by using mutation techniques. Gamma irradiation with the dose of 300 Gy was used to induce sorghum genetic variation. Through selection processes in several generations, the mutant line Zh-30 was identified to have better agronomic characteristics, better grain quality and higher grain yield than the original variety. Research on modified starch quality of this mutant line was done to identify its potential use in food industry. Functionality of pregelatinized, hydroxypropyl and crosslinked starch of this mutant line (Mutant TexInstant 30) has been studied for its use in high fiber muffin products. Characteristics of high fiber muffins containing 1.50; 3.50 and 5.50% of Mutant Tex-Instant 30 replacement levels to wheat flour were evaluated using both sensory panel and physical test methods. With regard to the sensory parameters, the high fiber muffins containing 1.50 - 5.50 % Mutant Tex-Instant 30 in general were not significantly different compared to the standard reference muffin. Results of physical evaluations showed that all Mutant Tex-Instant 30 containing products retained more moisture during baking than the standard reference. Tenderness of all products decreased at similar rate following 24 and 48 hr of room temperature storage and seven days at freezer temperature. These results suggested that sorghum mutant line Zh-30 starch could be modified and potentially used in food industry as a subtitute of wheat flour (author)

  12. Modified Starch of Sorghum Mutant Line Zh-30 for High Fiber Muffin Products

    Directory of Open Access Journals (Sweden)

    D.D.S. Santosa

    2009-01-01

    Full Text Available Sorghum mutant line Zh-30 is a breeding line developed at the Center for the Application of Isotope and Radiation Technology, BATAN by using mutation techniques. Gamma irradiation with the dose of 300 Gy was used to induce sorghum genetic variation. Through selection processes in several generations, the mutant line Zh-30 was identified to have better agronomic characteristics, better grain quality and higher grain yield than the original variety. Research on modified starch quality of this mutant line was done to identify its potential use in food industry. Functionality of pregelatinized, hydroxypropyl and crosslinked starch of this mutant line (Mutant TexInstant 30 has been studied for its use in high fiber muffin products. Characteristics of high fiber muffins containing 1.50; 3.50 and 5.50% of Mutant Tex-Instant 30 replacement levels to wheat flour were evaluated using both sensory panel and physical test methods. With regard to the sensory parameters, the high fiber muffins containing 1.50 - 5.50 % Mutant Tex-Instant 30 in general were not significantly different compared to the standard reference muffin. Results of physical evaluations showed that all Mutant Tex-Instant 30 containing products retained more moisture during baking than the standard reference. Tenderness of all products decreased at similar rate following 24 and 48 hr of room temperature storage and seven days at freezer temperature. These results suggested that sorghum mutant line Zh-30 starch could be modified and potentially used in food industry as a subtitute of wheat flour.

  13. Production of prostate-specific antigen by a breast cancer cell line, Sk-Br-3

    International Nuclear Information System (INIS)

    Kamali Sarvestani, E.; Ghaderi, A.

    2002-01-01

    Prostate-specific antigen is a 33-KDa serine protease that is produced predominantly by prostate epithelium. However, it has been shown that about 30-40% of female breast tumors produce prostate-specific antigen and its production is associated with the presence of estrogen and progesterone receptors. We have now developed a new tissue culture system to study prostate-specific antigen production in breast cancer and its association with prognostic factors such as progesterone receptor and c-erbB-2. For this purpose we investigated the ability of prostate-specific antigen production in five different cell lines, including two breast cancer cell lines, Sk-Br-3 and MDA-MB-453. The prostate-specific antigen in tissue culture supernatant and cytoplasm of the Sk-Br-3 cell line was detected by western blotting and immunoperoxidase, respectively. Furthermore, we found lower expression of c-erbB-2 in Sk-Br-3 than non-prostate-specific antigen producer breast cancer cell line, MDA-MB-453. Progesterone receptor was expressed by both prostate-specific antigen-positive and -negative cell lines and only the intensity of staining and the number of positive cells in Sk-Br-3 population was higher than MDA-MB-453. According to our findings prostate-specific antigen can be considered as a good prognostic factor in breast cancer and we suggest that these two cell lines are a good in vitro model to study the relationship of different breast cancer prognostic factors and their regulations

  14. Development of innovative inspection tools for higher reliability of PHWR fuel

    International Nuclear Information System (INIS)

    Kamalesh Kumar, B.; Viswanathan, B.; Laxminarayana, B.; Ganguly, C.

    2003-01-01

    'Full text:' Advent of Computer aided manufacturing systems has led to very high rate of production with greater reliability. The conventional inspection tools and systems, which are often manual based do not complement with output of highly automated production line. In order to overcome the deficiency, a strategic plan was developed for having automated inspection facility for PHWR fuel assembly line. Laser based systems with their inherently high accuracy and quick response times are a favorite for metrology purpose. Non-contact nature of laser-based measurement ensures minimal contamination, low wear and tear and good repeatability. So far two laser-based systems viz. Pellet density measurement systems and triangulation sensors have been developed. Laser based fuel pellet inspection system and PHWR fuel bundle metric station are under development. Machine vision-based systems have been developed to overcome certain limitations when inspection has to be carried out on such a large scale manually. These deficiencies arise from limitations of resolution, accessibility, fatigue and absence of quantification ability. These problems get further compounded in inspection of fuel components because of their relatively small sizes, close tolerances required and the reflective surfaces. PC based vision system has been developed for inspecting components and fuel assemblies. The paper would touch upon the details of the various laser systems and vision systems that have been indigenously developed for PHWR Fuel Metrology and their impact on the assembly production line. (author)

  15. The degradation of lining of rotary furnaces in the production of zinc oxide

    Directory of Open Access Journals (Sweden)

    Natália Luptáková

    2014-06-01

    Full Text Available This paper is closely connected with the complex problem of degradation relating to the refractories of rotary furnace linings in the production of zinc oxide. Zinc oxide can be produced by variety of ways, but the most common method of production which is used in Europe is indirect, i.e. pyrolytic combustion of zinc. This method is also called "French process" of manufacturing ZnO. But this mentioned method of preparation leads to the creation of the enormous amount of zinc slag including chemical complexes of elements Fe, Zn and Al. The mechanism of degradation of the lining leads to slag rests and it is closely connected with the mutual interaction of the aggressive agents with the components of the lining. This process creates a new undesired surface layer which increased the overall thickness of zinc slag. Stuck slag has the influence on rapid degradation of the linings and moreover it also decreases the production quality of ZnO. Analysis results introduced in this paper are significant information for minimizing of degradation of rotary furnaces.  

  16. Transmission line theory for long plasma production by radio frequency discharges between parallel-plate electrodes

    International Nuclear Information System (INIS)

    Nonaka, S.

    1991-01-01

    In order to seek for a radio frequency (RF) eigen-mode of waves in producing a plasma between a pair of long dielectric-covered parallel-plate RF electrodes, this paper analyzed all normal modes propagating along the electrodes by solving Maxwell's equations. The result showed that only an odd surface wave mode will produce the plasma in usual experimental conditions, which will become a basic transmission line theory when use of such long electrodes for on-line mass-production of amorphous silicon solar cells

  17. SPLLIFT: Statically Analyzing Software Product Lines in Minutes instead of Years

    DEFF Research Database (Denmark)

    Bodden, Eric; Tolêdo, Társis; Ribeiro, Márcio

    2013-01-01

    IFDS framework for inter-procedural, finite, distributive, subset problems to an SPL-aware analysis formulated in the IDE framework, a well-known extension to IFDS. Using a full implementation based on Heros, Soot, CIDE and JavaBDD, we show that with SPLLIFT one can reuse IFDS-based analyses without...... changing a single line of code. Through experiments using three static analyses applied to four Java-based product lines, we were able to show that our approach produces correct results and outperforms the traditional approach by several orders of magnitude....

  18. Genetic comparison of milk production and composition in three maternal rabbit lines

    Directory of Open Access Journals (Sweden)

    Ayman Gamal Fawzy EL Nagar

    2014-12-01

    Full Text Available The aim of this study was to compare 3 Spanish maternal rabbit lines (A, V and LP in terms of milk production and composition. These lines were founded on different criteria but selected for litter size at weaning. A total of 194 mature does in their third or higher parity were used. The milk yield of does was recorded at 1, 2, 3, 4, 8, 9, 10, 11, 15, 16 and 17 d post-partum (dpp. The milk production traits studied were weekly milk yield (WMY; g/wk and milk conversion ratio (MCR; grams of litter gain per grams of milk suckled during the first 21  dpp. The milk composition traits studied were fat (%, protein  (%, ash (%, lactose (% and total solids (%. The milk samples to be analysed were collected from each doe at 18 dpp. Data were analysed using single trait mixed and fixed models with and without covariates; the covariates were number born alive (NBA and doe weight at kindling (DW. The overall mean of WMY, during the first 3 wk, was 1547±16 g/wk. Milk yields during the different lactation weeks were for line A 872±39, 1503±39 and 1865±39 g for first, second and third lactation weeks, respectively. In line V, the corresponding values were 919±35, 1633±35 and 2004±35  g, and in line LP, they were 1043±36, 1819±36 and 2254±36  g. Means of MCR were 0.41±0.01, 0.41±0.01 and 0.42±0.01 for A, V and LP lines, respectively. Overall means of fat, protein, ash, lactose and total solids (% were 14.62±0.17, 11.10±0.07, 1.89±0.04, 2.67±0.12 and 30.27±0.24, respectively. The differences between lines for milk production traits were significant except for MCR, while the differences between lines for milk composition traits were not significant. NBA had significant effects on all milk yield traits but had no significant effects on milk composition traits. DW only had a significant effect on weekly milk yield. The parity order had no significant effect either for milk production traits or milk composition traits in multiparous does, except

  19. On-line Professional Learning Communities: Increasing Teacher Learning and Productivity in Isolated Rural Communities

    Directory of Open Access Journals (Sweden)

    Dora Salazar

    2010-08-01

    Full Text Available On-line and distance professional learning communities provides teachers with increased access and flexibility as well as the combination of work and education. It also provides a more learner-centered approach, enrichment and new ways of interacting with teachers in isolated rural areas. For educational administrators, on-line learning offers high quality and usually cost-effective professional development for teachers. It allows upgrading of skills, increased productivity and development of a new learning culture. At the same time, it means sharing of costs, of training time, increased portability of training, and the exchange of creativity, information, and dialogue.

  20. An Optimal Balancing of Multiple Assembly Line For a Batch Production Unit

    Directory of Open Access Journals (Sweden)

    M. Mohan Prasad

    2013-12-01

    Full Text Available Higher Productivity in organizations leads to national prosperity and better standard of living for the whole community. This has motivated several workers on productivity improvement at different levels of XXXX India Pvt Ltd, Chennai. The main objective of this project is to increase the production by changing the layout of the assembly line in making of Transmit Mixer. At present 12 machines are being manufactured in a total of 2 shifts per day. Time study is carried out to identify and avoid the idle time to increase the production rate to 24 machines per day. The organization facing the problems like production time, online inventory, delay and idle time. Here our objective is to reduce the idle time, identifying the cycle time and optimal method of production. The COMSOAL (Computer Method for Sequencing Operations for Assembly Lines and RPW (Ranked Positional Weight algorithms have been used to get the optimal solution. This algorithm provides the better solution, thereby reducing unnecessary movements of the worker within the station. The overall cycle time got reduced when compared with the existing cycle time in order to meet the customer demand. Thus we are proposing this scientific approach to get the optimal solution for increased rate of production of the company without affecting the quality and cost.

  1. A software product line approach to enhance a meta-scheduler middleware

    International Nuclear Information System (INIS)

    Scheidt, Rafael F; Schmidt, Katreen; Pessoa, Gabriel M; Viera, Matheus A; Dantas, Mario

    2012-01-01

    Software Projects in general tend to get more software reuse and componentization in order to reduce time, cost and new products resources. The need for techniques and tools to organize projects of higher quality in less time is one of the greatest challenges of Software Engineering. The Software Product Line is proposed to organize and systematically assist the development of new products in series at the same domain. In this context, this paper is proposed to apply the Software Product Line approach in Distributed Computing Environments. In projects that involve Distributed Environments, each version of the same product can generate repeatedly the same artifacts in a product that evolves its characteristics; however there is a principal architecture with variations of components. The goal of the proposed approach is to analyze the actual process and propose a new approach to develop new projects reusing the whole architecture, components and documents, starting with a solid base and creating new products focusing in new functionalities. We expect that with the application of this approach give support to the development of projects in Distributed Computing Environment.

  2. A Proposal for Production Data Collection on a Hybrid Production Line in Cooperation with MES

    Directory of Open Access Journals (Sweden)

    Znamenák Jaroslav

    2016-12-01

    Full Text Available Due to the increasing competitive environment in the manufacturing sector, many industries have the need for a computer integrated engineering management system. The Manufacturing Execution System (MES is a computer system designed for product manufacturing with high quality, low cost and minimum lead time. MES is a type of middleware providing the required information for the optimization of production from launching of a product order to its completion. There are many studies dealing with the advantages of the use of MES, but little research was conducted on how to implement MES effectively. A solution to this issue are KPIs. KPIs are important to many strategic philosophies or practices for improving the production process. This paper describes a proposal for analyzing manufacturing system parameters with the use of KPIs.

  3. A Proposal for Production Data Collection on a Hybrid Production Line in Cooperation with MES

    Science.gov (United States)

    Znamenák, Jaroslav; Križanová, Gabriela; Iringová, Miriam; Važan, Pavel

    2016-12-01

    Due to the increasing competitive environment in the manufacturing sector, many industries have the need for a computer integrated engineering management system. The Manufacturing Execution System (MES) is a computer system designed for product manufacturing with high quality, low cost and minimum lead time. MES is a type of middleware providing the required information for the optimization of production from launching of a product order to its completion. There are many studies dealing with the advantages of the use of MES, but little research was conducted on how to implement MES effectively. A solution to this issue are KPIs. KPIs are important to many strategic philosophies or practices for improving the production process. This paper describes a proposal for analyzing manufacturing system parameters with the use of KPIs.

  4. High performance liquid chromatographic analysis of insulin degradation products from a cultured kidney cell line

    International Nuclear Information System (INIS)

    Duckworth, W.C.; Hamel, F.G.; Liepnieks, J.; Frank, B.H.; Yagil, C.; Rabkin, R.

    1988-01-01

    The kidney is a major site for insulin removal and degradation, but the subcellular processes and enzymes involved have not been established. We have examined this process by analyzing insulin degradation products by HPLC. Monoiodoinsulin specifically labeled on either the A14 or B26 tyrosine residue was incubated with a cultured kidney epithelial cell line, and both intracellular and extracellular products were examined on HPLC. The products were then compared with products of known structure generated by hepatocytes and the enzyme insulin protease. Intracellular and extracellular products were different, suggesting two different degradative pathways, as previously shown in liver. The extracellular degradation products eluted from HPLC both before and after sulfitolysis similarly with hepatocyte products and products generated by insulin protease. The intracellular products also eluted identically with hepatocyte products. Based on comparisons with identified products, the kidney cell generates two fragments from the A chain of intact insulin, one with a cleavage at A13-A14 and the other at A14-A15. The B chain of intact insulin is cleaved in a number of different sites, resulting in peptides that elute identically with B chain peptides cleaved at B9-B10, B13-B14, B16-B17, B24-B25, and B25-B26. These similarities with hepatocytes and insulin protease suggest that liver and kidney have similar mechanisms for insulin degradation and that insulin protease or a very similar enzyme is involved in both tissues

  5. Using Software Product Line to improve ERP Engineering: Literature Review and Analysis

    Directory of Open Access Journals (Sweden)

    Raúl Mazo

    2014-10-01

    Full Text Available On the one hand, getting advantages of Enterprise Resource Planning (ERP systems largely depends on their capacity to be configured and adapted to fit the customer and domain requirements. On the other hand, product line engineering (PLE is a promising approach for configuring and adapting products by means of configuration and derivation processes. While the literature and industrial experiences show the benefits of PLE methods, techniques and tools, there is still a lack of interest in addressing ERP engineering issues with the product line strategy. Objective: The aim of this paper is to identify and analyze the different ways presented in the literature to improve ERP engineering issues with the methods, techniques and tools provided by PLE. Method: To achieve that objective, we reviewed the literature and analyzed available publications. Results: This literature review analyzes six research papers at the intersection between ERP and PLE. It shows that the product line strategy can indeed be applied for ERP configuration and customization. It further shows the evolving interest on this topic and discusses existing contributions.

  6. Lightweight Methods for Effective Verification of Software Product Lines with Off-the-Shelf Tools

    DEFF Research Database (Denmark)

    Iosif-Lazar, Alexandru Florin

    Certification is the process of assessing the quality of a product and whether it meets a set of requirements and adheres to functional and safety standards. I is often legally required to provide guarantee for human safety and to make the product available on the market. The certification process...... relies on objective evidence of quality, which is produced by using qualified and state-of-the-art tools and verification and validation techniques. Software product line (SPL) engineering distributes costs among similar products that are developed simultaneously. However, SPL certification faces major...... SPL reengineering projects that involve complex source code transformations. To facilitate product (re)certification, the transformation must preserve certain qualitative properties such as code structure and semantics—a difficult task due to the complexity of the transformation and because certain...

  7. Trustworthy Variant Derivation with Translation Validation for Safety Critical Product Lines

    DEFF Research Database (Denmark)

    Iosif-Lazăr, Alexandru Florin; Wasowski, Andrzej

    2016-01-01

    Software product line (SPL) engineering facilitates development of entire families of software products with systematic reuse. Model driven SPLs use models in the design and development process. In the safety critical domain, validation of models and testing of code increases the quality...... of the products altogether. However, to maintain this trustworthiness it is necessary to know that the SPL tools, which manipulate models and code to derive concrete product variants, do not introduce errors in the process. We propose a general technique of checking correctness of product derivation tools through...... translation validation. We demonstrate it using Featherweight VML—a core language for separate variability modeling relying on a single kind of variation point to define transformations of artifacts seen as object models. We use Featherweight VML with its semantics as a correctness specification...

  8. Productivity and Nutrient Quality of Some Sorghum Mutant Lines at Different Cutting Ages

    Directory of Open Access Journals (Sweden)

    R. E. Puteri

    2015-08-01

    Full Text Available The objective of the study was to explore the appropriate cutting age to produce optimal biomass and good nutrient quality from sorghum mutant lines BMR i.e., PATIR 3.5 M7, PATIR 3.6 M7, and PATIR 3.7 M7, also SAMURAI I (M17. A completely randomized in Split Plot design with 2 factors and 3 replicates was used. The first factor was the type of sorghum (SAMURAI I M17, PATIR 3.5, PATIR 3.6, PATIR 3.7 as the main plot and the second factor was the cutting age (85, 95, 105 as a subplot. Parameters observed were the production of stems, leaves, grains, total biomass production, ash, crude fat, crude fiber, crude protein, NFE, TDN, percentage of DMD, OMD and N-NH3. Data were analyzed by using ANOVA followed by DMRT (Duncan Multiple Range Test. The results showed that there were highly significant interactions (P<0.01 between cutting age and type of sorghum in production of stems, leaves, grains, total biomass production, value of TDN, DMD, OMD, and N-NH3. Increasing cutting age significantly increased the percentage of ash content, crude protein and crude fat. The sorghum type significantly affected crude fat content nonBMR sorghum variety of SAMURAI I (M17 and achieved optimal biomass production and nutrient content at cutting age of 85 d similar to BMR sorghum mutant lines PATIR 3.6 and PATIR 3.5, whereas BMR sorghum mutant lines of PATIR 3.7 achieved optimum production at the age of 95 d of cutting. All types of sorghum varieties was not recommended to be harvested at 105 d. Biomass production increased with the increasing of cutting age, but the nutrient content decreased.

  9. Productivity and fishing pressure drive variability in fish parasite assemblages of the Line Islands, equatorial Pacific.

    Science.gov (United States)

    Wood, Chelsea L; Baum, Julia K; Reddy, Sheila M W; Trebilco, Rowan; Sandin, Stuart A; Zgliczynski, Brian J; Briggs, Amy A; Micheli, Fiorenza

    2015-05-01

    Variability in primary productivity and fishing pressure can shape the abundance, species composition, and diversity of marine life. Though parasites comprise nearly half of marine species, their responses to these important forces remain little explored. We quantified parasite assemblages at two spatial scales, across a gradient in productivity and fishing pressure that spans six coral islands of the Line Islands archipelago and within the largest Line Island, Kiritimati, which experiences a west-to-east gradient in fishing pressure and upwelling-driven productivity. In the across-islands data set, we found that increasing productivity was correlated with increased parasite abundance overall, but that the effects of productivity differed among parasite groups. Trophically transmitted parasites increased in abundance with increasing productivity, but directly transmitted parasites did not exhibit significant changes. This probably arises because productivity has stronger effects on the abundance of the planktonic crustaceans and herbivorous snails that serve as the intermediate hosts of trophically transmitted parasites than on the higher-trophic level fishes that are the sole hosts of directly transmitted parasites. We also found that specialist parasites increased in response to increasing productivity, while generalists did not, possibly because specialist parasites tend to be more strongly limited by host availability than are generalist parasites. After the effect of productivity was controlled for, fishing was correlated with decreases in the abundance of trophically transmitted parasites, while directly transmitted parasites appeared to track host density; we observed increases in the abundance of parasites using hosts that experienced fishing-driven compensatory increases in abundance. The within-island data set confirmed these patterns for the combined effects of productivity and fishing on parasite abundance, suggesting that our conclusions are robust

  10. Fuel assembly inspection device

    International Nuclear Information System (INIS)

    Yaginuma, Yoshitaka

    1998-01-01

    The present invention provides a device suitable to inspect appearance of fuel assemblies by photographing the appearance of fuel assemblies. Namely, the inspection device of the present invention measures bowing of fuel assembly or each of fuel rods or both of them based on the partially photographed images of fuel assembly. In this case, there is disposed a means which flashily projects images in the form of horizontal line from a direction intersecting obliquely relative to a horizontal cross section of the fuel assembly. A first image processing means separates the projected image pictures including projected images and calculates bowing. A second image processing means replaces the projected image pictures of the projected images based on projected images just before and after the photographing. Then, images for the measurement of bowing and images for inspection can be obtained simultaneously. As a result, the time required for the photographing can be shortened, the time for inspection can be shortened and an effect of preventing deterioration of photographing means by radiation rays can be provided. (I.S.)

  11. Production of Multiple Growth Factors by a Newly Established Human Thyroid Carcinoma Cell Line

    Science.gov (United States)

    Yoshida, Yataro; Ohashi, Kensaku; Sano, Emiko; Kobayashi, Hisataka; Endo, Keigo; Naruto, Masanobu; Nakamura, Toru

    1992-01-01

    A multiple growth factor‐producing tumor cell line (NIM‐1) was newly established from a patient with thyroid cancer and remarkable neutrophilia. NIM‐1 cells also caused severe neutrophilia in nude mice bearing tumors. NIM‐1‐conditioned medium (NIM‐1CM) contained activities that supported not only granulocyte, macrophage and eosinophil colony formation of human bone marrow cells but also the growth of colony‐stimulating factor (CSF)‐dependent cell lines, NFS60‐KX and TF‐1. Northern blot hybridization analysis revealed the constitutive expression of granulocyte‐CSF (G‐CSF), granulocyte/macrophage‐CSF (GM‐CSF) and interleukin(IL)‐6 mRNAs in NIM‐1 cells. Enzyme‐linked immunosorbent assays (ELISA) using NIM‐1CM also confirmed the production of IL‐la and a small amount of IL‐1β besides G‐CSF, GM‐CSF and IL‐6 in NIM‐1 cells. In addition, unexpected production of IL‐11 in NIM‐1 cells was detected by northern blot hybridization analysis and by bioassay using an IL‐11‐dependent cell line. Therefore, NIM‐1 cell line is shown to produce multiple cytokines including potentially megakaryopoietic growth factors such as GM‐CSF, IL‐6 and IL‐11. PMID:1372885

  12. Sex effect on productive parameters, carcass and body fat composition of two commercial broilers lines

    Directory of Open Access Journals (Sweden)

    S Rondelli

    2003-12-01

    Full Text Available The aim of this work was to evaluate sex effect on behavior of two commercial broilers lines. Productive parameters, carcass composition and yield, amount and quality of fat deposited in the meat and skin and total body fat were studied. A completely randomized design with four treatments (MR-Male Ross, HR-Female Ross, MAF-Male Avian Farm and HAF-Female Avian Farm and eight repetitions of 40 chickens was used. Animals received water and food ad libitum. After 50 days, two birds (a male and a female per repetition were chosen at random and slaughtered for carcass evaluation. Samples of breast, leg, skin and abdominal fats were analyzed to determine the percentage of intramuscular fat, total cholesterol and fatty acid composition. The Ross line showed higher final weight and weight gain, better intake and feed conversion rate. Also, it was observed that females of both lines had similar results in relation to these parameters. Better yield of breast with bone was found in Ross males and females. In relation to legs and thigh, Ross males showed better results and no differences were observed among females of both lines. Males deposited less fat than females. Finally, differences in percentage of intramuscular fat, content of cholesterol in breast with skin, leg with skin and skin, percentage of saturated, mono and polyunsaturated fatty acids were observed between sex and lines.

  13. Balancing Disassembly Line in Product Recovery to Promote the Coordinated Development of Economy and Environment

    Directory of Open Access Journals (Sweden)

    Jia Liu

    2017-02-01

    Full Text Available For environmentally conscious and sustainable manufacturing, many more manufacturers are acting to recycle and remanufacture their post-consumed products. The most critical process of remanufacturing is disassembly, since it allows for the selective extraction of the valuable components and materials from returned products to reduce the waste disposal volume. It is, therefore, important to design and balance the disassembly line to work efficiently due to its vital role in effective resource usage and environmental protection. Considering the disassembly precedence relationships and sequence-dependent parts removal time increments, this paper presents an improved discrete artificial bee colony algorithm (DABC for solving the sequence-dependent disassembly line balancing problem (SDDLBP. The performance of the proposed algorithm was tested against nine other approaches. Computational results evidently indicate the superior efficiency of the proposed algorithm for addressing the environmental and economic concerns while optimizing the multi-objective SDDLBP.

  14. Micro-Injection Moulding In-Line Quality Assurance Based on Product and Process Fingerprints

    DEFF Research Database (Denmark)

    Baruffi, Federico; Calaon, Matteo; Tosello, Guido

    2018-01-01

    significant dimensional features of the micro part were measured using a focus variation microscope. Their dependency on the variation of µIM process parameters was studied with a Design of Experiments (DoE) statistical approach. A correlation study allowed the identification of the product fingerprint, i...... of the study showed that the dimensional quality of the micro component could be effectively controlled in-line by combining the two fingerprints, thus opening the door for future µIM in-line process optimization and quality assessment.......Micro-injection moulding (μIM) is a replication-based process enabling the cost-effective production of complex and net-shaped miniaturized plastic components. The micro-scaled size of such parts poses great challenges in assessing their dimensional quality and often leads to time...

  15. Product line based ontology reuse in context-aware e-business environment

    DEFF Research Database (Denmark)

    Zhang, Weishan; Kunz, Thomas

    2006-01-01

    Improving the reusability of ontology is recognized as increasingly important due to the prevalence of OWL research and applications. But there exists no convincing methodology and tool support in this direction yet. In this paper, we apply ideas from the research and practice with software product...... lines in order to explore this issue. The ontology is developed and managed according to the commonalities and variabilities underlying a specific problem domain. Meta-ontology is used in order to improve the reusability, evolve-ability and customizability of ontology. Another advantage is being able...... to generate needed ontology with the created meta-ontology implemented with XVCL (XML based Variant Configuration Language) technology. We demonstrate our product line based reuse approach with an example B2C application....

  16. Synergy between Software Product Line and Intelligent Pervasive Middleware-a PLIPerM Approach

    DEFF Research Database (Denmark)

    Zhang, Weishan

    2008-01-01

    with OWL ontology reasoning enhanced BDI (Belief-Desire-Intention) agents, which are the basic building blocks of PLIPerM. Besides the advantages of a software product line, our approachcan handle ontology evolution and keep all related assets in a consistent state. Other advantages include the ability...... to configure Jadex BDI agents for different purpose and to enhance agent intelligence by adding logic reasoning capabilities indirectly to agent beliefs....

  17. Modes in Component Behavior Specification via EBP and their Application in Product Lines

    Czech Academy of Sciences Publication Activity Database

    Kofroň, Jan; Plášil, František; Šerý, O.

    2009-01-01

    Roč. 51, č. 1 (2009), s. 31-41 ISSN 0950-5849 R&D Projects: GA AV ČR 1ET400300504 Grant - others:GA ČR(CZ) GA201/08/0266 Institutional research plan: CEZ:AV0Z10300504 Keywords : behavior specification * component modes * software product lines Subject RIV: JC - Computer Hardware ; Software Impact factor: 1.821, year: 2009

  18. The impact of bad fit product line extensions on brand personality

    OpenAIRE

    Lima, Pedro

    2017-01-01

    This work project intended to study the impact of a bad fit product line extension on brand personality. To do that, the focus of the study was narrowed down to one dimension of the brand personality, ruggedness, and another one as a comparative dimension, sophistication. The test consisted in the introduction of a bad fit extension by two brands: Harley-Davidson and Jaguar. The findings show us that a bad fit extension has more impact in the sophistication dimension (increased the dimension ...

  19. Evaluation of angular distributions and production cross-sections for discrete gamma lines in iron

    International Nuclear Information System (INIS)

    Savin, M.V.; Livke, A.V.; Zvenigorodskij, A.G.

    2001-01-01

    The experimental data were compiled and the angular distributions and production cross-sections for the E γ = 846.8, 1238.3 and 1810.8 keV discrete gamma-lines evaluated. The Legendre polynomial coefficients describing the angular distributions in the energy range up to E n = 14.0 MeV and cross-section values in the E n = 0.85-19.0 MeV range were evaluated. (author)

  20. EXPERIENCES INITIATING SOFTWARE PRODUCT LINE ENGINEERING IN SMALL TEAMS WITH PULSE

    DEFF Research Database (Denmark)

    Mærsk-Møller, Hans Martin; Jørgensen, Bo Nørregaard

    2010-01-01

    Small teams of software engineers are represented both in small companies and semi-independent fractions in medium and large companies. Even though some results and experience papers have been published in the context of Small- and Medium-Sized Enterprises (SMEs), there is a lack of experience pa...... an existing methodology, PuLSETM, drew advantages of NetBeans Rich Client Platform, and based the product line on the existing application....

  1. Discussion after implementation of possible ergonomics contributions in production lines automation project

    OpenAIRE

    José Adriano Canton; Andrea Regina Martins Fontes; Isaías Torres

    2016-01-01

    This paper addresses the issue of work spaces designed based on Activity-Centered Ergonomics. The aim was to reflect on the role of Ergonomics in the design of productive situations in order to anticipate and mitigate the emergence of new constraints. This study was developed using a case study from the packaging industry, where an automated line was implemented to mitigate the injuries suffered as result of the manual system. This article was based on the results of an Ergonomic Work Analysi...

  2. Endogenous pyrogen production by Hodgkin's disease and human histiocytic lymphoma cell lines in vitro.

    OpenAIRE

    Bodel, P; Ralph, P; Wenc, K; Long, J C

    1980-01-01

    Fever not explained by infection may occur in patients with malignant lymphoma presumably caused by a release of endogenous pyrogen. Although pyrogen has been found in some tumors with a mixed cell population, production of endogenous pyrogen by the neoplastic cells has not been demonstrated. This report documents the apparently spontaneous synthesis and release of such pyrogen by two human tumor cell lines derived from patients with Hodgkin's disease and histiocytic lymphoma. The endogenous ...

  3. The series production in a standardized fabrication line for silicide fuels and commercial aspects

    International Nuclear Information System (INIS)

    Wehner, E.L.; Hassel, H.W.

    1987-01-01

    NUKEM has been responsible for the development and fabrication of LEU fuel elements for MTR reactors under the frame of the German AF program since 1979. The AF program is part of the international RERTR efforts, which were initiated by the INFCE Group in 1978. This paper describes the actual status of development and the transition from the prototype to the series production in a standardized manufacturing line for silicide fuels at NUKEM. Technical provisions and a customer oriented standardized product range aim at an economized manufacturing. (Author)

  4. Temperature-dependence of Threshold Current Density-Length Product in Metallization Lines: A Revisit

    International Nuclear Information System (INIS)

    Duryat, Rahmat Saptono; Kim, Choong-Un

    2016-01-01

    One of the important phenomena in Electromigration (EM) is Blech Effect. The existence of Threshold Current Density-Length Product or EM Threshold has such fundamental and technological consequences in the design, manufacture, and testing of electronics. Temperature-dependence of Blech Product had been thermodynamically established and the real behavior of such interconnect materials have been extensively studied. The present paper reviewed the temperature-dependence of EM threshold in metallization lines of different materials and structure as found in relevant published articles. It is expected that the reader can see a big picture from the compiled data, which might be overlooked when it was examined in pieces. (paper)

  5. The degradation of lining of rotary furnaces in the production of zinc oxide

    OpenAIRE

    Natália Luptáková; Evgeniy Anisimov; Františka Pešlová

    2014-01-01

    This paper is closely connected with the complex problem of degradation relating to the refractories of rotary furnace linings in the production of zinc oxide. Zinc oxide can be produced by variety of ways, but the most common method of production which is used in Europe is indirect, i.e. pyrolytic combustion of zinc. This method is also called "French process" of manufacturing ZnO. But this mentioned method of preparation leads to the creation of the enormous amount of zinc slag including ch...

  6. Experimental on-line platform for product conceptual design: OpenDesigNet

    Directory of Open Access Journals (Sweden)

    Teresa Magal-Royo

    2013-09-01

    Full Text Available This paper highlights the need for using specialised on-line collaborative environments by designers and product engineers who increasingly use Web 2.0 technology to search for information. Although there are professional channels and networks, there is no specific platform which helps during a new product’s conceptualisation phase. Open communication must thus be promoted and encouraged amongst design professionals and companies to form working groups thereby allowing them to work collaboratively in the most open and creative phase of product design, i.e. conceptualisation. The OpenDesigNet (ODN experimental platform has been developed so that designers and small- or medium-sized companies (SMC can access on-line collaborative tools to support the creation and promotion of new on-line products and assess their immediate social impact. This article presents some of the results obtained during the validation phase involving a platform satisfaction survey of design engineering students and has led to a first-hand assessment of the new platform’s potential impact on their professional future.

  7. On-line tritium production and heat deposition rate measurements at the Lotus facility

    International Nuclear Information System (INIS)

    Joneja, O.P.; Scherrer, P.; Anand, R.P.

    1994-01-01

    Integral tritium production and heat deposition measurement in a prototype fusion blanket would enable verification of the computational codes and the data based employed for the calculations. A large number of tritium production rate measurements have been reported for different type of blankets, whereas the direct heat deposition due to the mixed radiation field in the fusion environment, is still in its infancy. In order to ascertain the kerma factors and the photon production libraries, suitable techniques must be developed to directly measure the nuclear heat deposition rates in the materials required for the fusion systems. In this context, at the Lotus facility, we have developed an extremely efficient double ionizing chamber, for the on-line tritium production measurements and employed a pure graphite calorimeter to measure the nuclear heat deposition due to the mixed radiation field of the 14 MeV, Haefely neutron generator. This paper presents both systems and some of the recent measurements. (authors). 8 refs., 13 figs

  8. Gas exchange, heat production and oxidation of fat in chicken embryos from a fast or slow growing line

    DEFF Research Database (Denmark)

    Chwalibog, André; Tauson, Anne-Helene; Ali, Abdalla

    2007-01-01

    The experiment comprised 48 chicken (Gallus gallus) embryos from a modern, fast growing line, Ross 308 (RO) and 48 from a slow growing line, Labresse (LA). The O(2) consumption and CO(2) production were measured in an open-air-circuit respiration unit, and heat production (HE) from embryos was ca...

  9. 40 CFR 1048.320 - What happens if one of my production-line engines fails to meet emission standards?

    Science.gov (United States)

    2010-07-01

    ...-line engines fails to meet emission standards? 1048.320 Section 1048.320 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM NEW, LARGE NONROAD SPARK-IGNITION ENGINES Testing Production-line Engines § 1048.320 What happens if one of my production...

  10. 78 FR 63162 - Certain Lined Paper Products From India: Notice of Partial Rescission and Preliminary Results of...

    Science.gov (United States)

    2013-10-23

    ... DEPARTMENT OF COMMERCE International Trade Administration [A-533-843] Certain Lined Paper Products... certain lined paper products (CLPP) from India.\\2\\ The period of review (POR) is September 1, 2011... Petitioners are the Association of American School Paper Suppliers (AASPS) and its individual members. \\2\\ See...

  11. 9 CFR 381.71 - Condemnation on ante mortem inspection.

    Science.gov (United States)

    2010-01-01

    ... dressed, nor shall they be conveyed into any department of the official establishment where poultry... AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION POULTRY PRODUCTS INSPECTION REGULATIONS Ante Mortem Inspection § 381.71...

  12. RIMACS, Reactor Inspection Main Control System

    International Nuclear Information System (INIS)

    2008-01-01

    1 - Description of program or function: RIMACS prepares for automatic inspection files on each inspection item for the reactor. These automatic inspection files provide the data to move RIROB (Reactor Inspection Robot) with laser by interpreting the coordinates of LASPO (Laser Positioner) and the laser detecting device of RIROB in three dimensional space. In addition, when RIROB arrives at the inspecting location, the files provide all values of the manipulator's motions to acquire the ultrasonic data. RIMACS provides various modules in order to perform these complex functions, and the functions are programmed on graphic user interface for the convenience of the user. RIMACS provides various functions, such as insertion of reactor production data, selection of the reactor for inspection, the creation of automatic inspection file, the selection of the inspection item, inspection simulation, and automatic inspection procedures. It also provides all other functions, which are necessary for the inspection, such as operating program download and manual control of LASPO and RIROB, the inspection simulation and the inspection status display by means of the graphic screen, and SODAS (ultra-Sonic Data Acquisition System) drive verification. 2 - Methods: Moving path and operation procedures for inspection robot are generated automatically with Kinematics algorithm. 3 - Restrictions on the complexity of the problem: A graphics display with MS-Window capability is required

  13. 9 CFR 381.76 - Post-mortem inspection, when required; extent; traditional, Streamlined Inspection System (SIS...

    Science.gov (United States)

    2010-01-01

    ...; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION POULTRY PRODUCTS... (NELS) Inspection System, both of which shall be used only for broilers and cornish game hens; the New... Inspection. (i) The SIS shall be used only for broilers and cornish game hens if: (a) The Administrator...

  14. On-line measurement and control in sustainable mineral processing and energy production

    International Nuclear Information System (INIS)

    Sowerby, B.D.

    2002-01-01

    Sustainable development can be defined as development that 'meets the needs of the present without compromising the ability of future generations to meet their own needs' (WCED, 1987). A sustainable minerals and energy industry will need to achieve a number of related objectives including greater energy efficiency, improved utilisation of ore deposits, improved utilisation of existing plant, improved product quality, reduction of waste material, reduction of pollution levels and improved safety margins. These objectives all relate in varying degrees to the triple bottom line of economic, social and environmental benefits. One critical component in achieving these objectives is to develop and apply improved control systems across the full range of industry applications from mining to processing and utilisation. However process control relies heavily on the availability of suitable on-line process instrumentation to provide the data and feedback necessary for its implementation. There is a lot of truth in the saying 'if you can't measure it you can't control it'. In the past measurement was achieved by manual sampling followed by sample preparation (such as drying, mixing, crushing and dividing) and off-line laboratory analysis. However this procedure is often subject to significant sampling errors and, most importantly, the measurements are too slow for control purposes. By contrast, on-line analysis can provide rapid and accurate measurement in real time thus opening up new possibilities for improved process control. As a result, there has been a rapid increase in the industrial application of on-line analysis instrumentation over the past few decades. The main purpose of this paper is to briefly review some past Australian developments of on-line analysis systems in the mineral and coal industries and to discuss present developments and future trends

  15. Ethanol production from lignocellulosic materials. Fermentation and on-line analysis

    Energy Technology Data Exchange (ETDEWEB)

    Olsson, L.

    1994-04-01

    The fermentation performance of bacteria, yeast and fungi was investigated in lignocellulosic hydrolysates with the aim of finding microorganisms which both withstand the inhibitors and that have the ability to ferment pentoses. Firstly, the performance of Saccharomyces cidri, Saccharomyces cerevisiae, Lactobacillus brevis, Lactococcus lactis ssp lactis, Escherichia coli and Zymomonas mobilis was investigated in spent sulphite liquor and enzymatic hydrolysate of steam-pretreated willow. Secondly, the performance of natural and recombinant E. coli, Pichia stipitis, recombinant S. cerevisiae, S. cerevisiae in combination with xylose isomerase and Fusarium oxysporum was investigated in a xylose-rich acid hydrolysate of corn cob. Recombinant E. coli was the best alternative for fermentation of lignocellulosic hydrolysates, giving both high yields and productivities. The main drawback was that detoxification was necessary. The kinetics of the fermentation with recombinant E. coli KO11 was investigated in the condensate of steam-pretreated willow. A cost analysis of the ethanol production from willow was made, which predicted an ethanol production cost of 3.9 SEK/l for the pentose fermentation. The detoxification cost constituted 22% of this cost. The monitoring of three monosaccharides and ethanol in lignocellulosic hydro lysates is described. The monosaccharides were determined using immobilized pyranose oxidase in an on-line amperometric analyser. Immobilization and characterization of pyranose oxidase from Phanerochaete chrysosporium is also described. The ethanol was monitored on-line using a micro dialysis probe as an in situ sampling device. The dialysate components were then separated in a column liquid chromatographic system and the ethanol was selectively detected by an amperometric alcohol bio sensor. The determinations with on-line analysis methods agreed well with off-line methods. 248 refs, 4 figs, 12 tabs

  16. Inspection of Emergency Arrangements

    International Nuclear Information System (INIS)

    2013-01-01

    NPPs. - Where RBs have an influence over land use around NPPs, they use the knowledge of their local or resident inspectors to inform decisions. - Inspectors check that appropriate action levels or criteria to identify an actual or radiological emergency are clearly defined and readily available to decision makers. - When observing emergency exercises inspectors check that: an appropriate and timely declaration is made, plant operators respond in accordance with the emergency plan and emergency instructions, and an appropriate level of response is initiated on and off-site. - RBs conduct follow-up inspections after real events, to ensure that the correct emergency response has been followed. - Inspectors verify that reliable data will be used to support the evaluation of environmental impact from a nuclear or radiological emergency, to the extent that this is within the jurisdiction of the RB. - Routine inspections and emergency exercise observations include a check that lines of communication are sufficiently resilient. - When observing emergency exercises inspectors, where practicable, check that timely, accurate and consistent information is provided to the public, in accordance with the off-site emergency plan. - RBs inspect the ability of the operator to give accurate medical and radiological information about casualties, to enable the correct treatment to be given. - Additional emergency equipment that is held in reserve off-site, provided to enhance resilience (post Fukushima), is included in the RB planned inspection and/or emergency exercise programme. - Inspectors check that licensee staff are adequately trained to connect and use additional equipment provided to enhance resilience. - Inspectors utilise the NPP operator's approved on-site emergency plan when inspecting on-site emergency arrangements. - RBs include human factors staff in emergency exercise evaluation teams to consider safety culture and human performance. - RBs consider the need for exercise

  17. Radiography inspection of weld for nuclear fuel rod

    International Nuclear Information System (INIS)

    Zhang Kai; Zhang Xichang

    1995-05-01

    The survey of radiography inspection, advantages, disadvantages and applications of main kinds of radiography inspection methods are presented. Emphasis is put upon the structure and functions of X-ray flaw detecting device for nuclear fuel rod welds, the actuating program of the device, as well as the structure of some key mechanism and the functions of them. The analysis is made upon the actuating principles. Finally, the test of long-term operation proves the device to be stable in operation, reliable in action, to possess high level of automation and high sensitivity and it can simultaneously perform on-line X-ray inspection of 25 nuclear fuel rods with a diameter less than 10 mm, and meet the requirements of large-scale production of nuclear fuel rods (5 figs.)

  18. Continuous determination of volatile products in anaerobic fermenters by on-line capillary gas chromatography

    International Nuclear Information System (INIS)

    Diamantis, V.; Melidis, P.; Aivasidis, A.

    2006-01-01

    Bio-ethanol and biogas produced during the anaerobic conversion of organic compounds has been a subject of great interest since the oil crisis of the 1970s. In ethanol fermentation and anaerobic treatment of wastewaters, end-product (ethanol) and intermediate-products (short-chain fatty acids, SCFA) cause inhibition that results in reduced process efficiency. Control of these constituents is of utmost importance for bioreactor optimization and process stability. Ethanol and SCFA can be detected with precision by capillary gas chromatography usually conducted in off-line measurements. In this work, an on-line monitoring and controlling system was developed and connected to the fermenter via an auto-sampling equipment, which could perform the feeding, filtration and dilution of the sample and final injection into the gas chromatograph through an automation-based programmed procedure. The sample was continuously pumped from the recycle stream of the bioreactor and treated using a microfiltration unit. The concentrate was returned to the reactor while the permeate was quantitatively mixed with an internal standard solution. The system comprised of a gas chromatograph with the flow cell and one-shot sampler and a PC with the appropriate software. The on-line measurement of ethanol and SCFA, directly from the liquid phase of an ethanol fermenter and a high-rate continuous mode anaerobic digester, was accomplished by gas chromatography. Also, this monitoring and controlling system was proved to be effective in the continuous fermentation of alcohol-free beer

  19. Endogenous pyrogen production by Hodgkin's disease and human histiocytic lymphoma cell lines in vitro.

    Science.gov (United States)

    Bodel, P; Ralph, P; Wenc, K; Long, J C

    1980-02-01

    Fever not explained by infection may occur in patients with malignant lymphoma presumably caused by a release of endogenous pyrogen. Although pyrogen has been found in some tumors with a mixed cell population, production of endogenous pyrogen by the neoplastic cells has not been demonstrated. This report documents the apparently spontaneous synthesis and release of such pyrogen by two human tumor cell lines derived from patients with Hodgkin's disease and histiocytic lymphoma. The endogenous pyrogen from the two cell lines was similar and closely resembled that produced by normal human monocytes in antigenic properties as well as heat and pronase sensitivity. The Hodgkin's disease and histiocytic lymphoma cell lines do not require specific stimulation for the production of endogenous pyrogen suggesting that the mechanism of pyrogen release by neoplastic macrophage-related cells differs from that of normal phagocytic cells. The tumor-associated fever in some patients with malignant lymphoma may be caused by a release of endogenous pyrogen by proliferating neoplastic cells.

  20. Incore inspection and repairing device

    International Nuclear Information System (INIS)

    Ito, Arata; Kimura, Motohiko

    1998-01-01

    The present invention provides a device for inspecting and repairing the inside of a reactor container even if it is narrow, with no trouble by using a swimming-type operation robot. Namely, the device of the present invention conducts inspection and repairing operations for the inside of the reactor by introducing a swimming type operation robot into the reactor container. The swimming-type operation robot comprises a robot main body having a propeller, a balancer operably disposed to the robot main body and an inspection and repairing unit attached detachable to the balancer. In the device of the present invention, since the inspection and preparing unit is attached detachably to the swimming robot, a robot which transports tools is formed as a standard product. As a result, the production cost can be reduced, and the reliability of products can be improved. Appropriate operations can be conducted by using best tools. (I.S.)

  1. Comparison of growth performance and immune parameters of three commercial chicken lines used in organic production

    DEFF Research Database (Denmark)

    Kjærup, Rikke Brødsgaard; Juul-Madsen, Helle Risdahl; Norup, Liselotte Rothmann

    2017-01-01

    Owing to the higher demands for avoiding medication and antibiotics, health status of the production animals plays an important role in the poultry industry, especially in organic poultry systems. Immunity plays a major role in keeping the host free from disease, and it is evident that the host...... of chickens with a more general and broad disease resistance or robustness may therefore improve the overall health status, animal welfare, and food security in the poultry production. The aim of this study was therefore to compare the immunocompetence of the presumed “robust” Hellevad chickens with two...... chicken lines widely used in organic production, Bovans Brown (Bovans) and Hisex White (Hisex). The chickens were subjected to a routine vaccination program comprising one parasite and four viral vaccines. The current study indicates that considerable differences in immunocompetence may exist between...

  2. Managing the risks of the backfill production line from material acquisition to installation

    International Nuclear Information System (INIS)

    Kiviranta, Leena; Kumpulainen, Sirpa; Keto, Paula; Autio, Jorma; Siivonen, Markku; Koho, Petri

    2012-01-01

    Document available in extended abstract form only. The tunnel backfill of Finnish KBS-3V type repository for spent nuclear fuel consists of foundation layer that is installed at site, pre-compacted backfill blocks that fill most of the tunnel and bentonite pellets to fill the gap between blocks and tunnel wall. In order to ensure the quality, availability, and timely delivery of backfill materials and components, and further to ensure the fulfillment of the requirements and specifications set for backfilling of deposition tunnels, the backfill production line was explored step-by-step, and risks related were defined and analyzed. The work described in this paper was initiated by Posiva Oy and is reported in Keto et al. (2012). The first part of the backfill production line is described in Figure 1 for Friedland clay that is designed to be used for the backfill blocks. It consists of excavation, processing and delivery of materials to backfill production facility. Second part of the production line consists of manufacturing of the backfill components, and the third part is the installation. A preliminary risk assessment was done in 2011 for the acquisition of Friedland clay and manufacturing and installation of foundation layer, blocks and pellets. The critical points of the production line were determined using a material flow description where risk is defined as a probability of something unwanted to happen times the severity of the consequences. Risk analysis was performed by going through the whole backfill production line step by step and analyzing all the incidents, which have occurred (or might occur) during the backfilling operations. A risk number from 1 to 25 was given to each step of the chain depending on how long delay the problem causes and how often it occurs. Low risk was the target for each step of the chain, medium risk was considered tolerable, for high risks management actions to decrease the risk number were considered and extremely high risks

  3. An avian cell line designed for production of highly attenuated viruses.

    Science.gov (United States)

    Jordan, Ingo; Vos, Ad; Beilfuss, Stefanie; Neubert, Andreas; Breul, Sabine; Sandig, Volker

    2009-01-29

    Several viral vaccines, including highly promising vectors such as modified vaccinia Ankara (MVA), are produced on chicken embryo fibroblasts. Dependence on primary cells complicates production especially in large vaccination programs. With primary cells it is also not possible to create packaging lines for replication-deficient vectors that are adapted to proliferation in an avian host. To obviate requirement for primary cells permanent lines from specific tissues of muscovy duck were derived (AGE1.CR, CS, and CA) and further modified: we demonstrate that stable expression of the structural gene pIX from human adenovirus increases titers for unrelated poxvirus in the avian cells. This augmentation appears to be mediated via induction of heat shock and thus provides a novel cellular substrate that may allow further attenuation of vaccine strains.

  4. Fast Industrial Inspection of Optical Thin Film Using Optical Coherence Tomography

    Directory of Open Access Journals (Sweden)

    Muhammad Faizan Shirazi

    2016-09-01

    Full Text Available An application of spectral domain optical coherence tomography (SD-OCT was demonstrated for a fast industrial inspection of an optical thin film panel. An optical thin film sample similar to a liquid crystal display (LCD panel was examined. Two identical SD-OCT systems were utilized for parallel scanning of a complete sample in half time. Dual OCT inspection heads were utilized for transverse (fast scanning, while a stable linear motorized translational stage was used for lateral (slow scanning. The cross-sectional and volumetric images of an optical thin film sample were acquired to detect the defects in glass and other layers that are difficult to observe using visual inspection methods. The rapid inspection enabled by this setup led to the early detection of product defects on the manufacturing line, resulting in a significant improvement in the quality assurance of industrial products.

  5. Product-line extensions and pricing strategies of brand-name drugs facing patent expiration.

    Science.gov (United States)

    Hong, Song Hee; Shepherd, Marvin D; Scoones, David; Wan, Thomas T H

    2005-01-01

    This study proposed an alternative to brand loyalty as the explanation for the continued price rigidity of patent-expired brand-name prescription drugs despite the increase in market entry of generic drugs facilitated by the 1984 Drug Price Competition and Patent Term Restoration Act. Study hypotheses were to test (1) whether market entries of new-product extensions are associated with market success of original brand-name drugs before generic drug entry, and (2) whether original brand-name drugs exhibit price rigidity to generic entry only when they are extended. The design is a retrospective follow-up study for the prescription drug brands that lost their patents between 1987 and 1992. The drug brands were limited to nonantibiotic, orally administered drugs containing only 1 active pharmaceutical ingredient. Information on patent expiration, entry of a product extension, and market success were determined from the U.S. Food and Drug Administration.s Orange Book, First DataBank, and American Druggist, respectively. Market success was defined as whether an original drug brand was listed in the top 100 prescriptions most frequently dispensed before facing generic entry. Product-line extension was defined as the appearance of another product that a company introduces within the same market after its existing product. Drug prices were average wholesale prices from the Drug Topics Red Book. The relationship between product-line extension and market success was examined using a logistic regression analysis. The price rigidity to entry was tested using a panel regression analysis. A total of 27 drug brands lost their patents between 1987 and 1992. Drug brands that achieved market success were 16 times more likely to be extended than were those that did not (OR=16, 95% confidence interval, 2.12-120.65). The price rigidity to entry existed in drug brands with extensions (beta=2.65%, P new product-line extension introduced for an original brand helps the original price be

  6. Oncostatin M promotes STAT3 activation, VEGF production, and invasion in osteosarcoma cell lines

    International Nuclear Information System (INIS)

    Fossey, Stacey L; Bear, Misty D; Kisseberth, William C; Pennell, Michael; London, Cheryl A

    2011-01-01

    We have previously demonstrated that both canine and human OSA cell lines, as well as 8 fresh canine OSA tumor samples, exhibit constitutive phosphorylation of STAT3, and that this correlates with enhanced expression of matrix metalloproteinase-2 (MMP2). While multiple signal transduction pathways can result in phosphorylation of STAT3, stimulation of the cytokine receptor gp130 through either IL-6 or Oncostatin M (OSM) is the most common mechanism through which STAT3 is activated. The purpose of this study was to evaluate the role of IL-6 and OSM stimulation on both canine and human OSA cell lines to begin to determine the role of these cytokines in the biology of OSA. RT-PCR and Western blotting were used to interrogate the consequences of OSM and IL-6 stimulation of OSA cell lines. OSA cells were stimulated with OSM and/or hepatocyte growth factor (HGF) and the effects on MMP2 activity (gel zymography), proliferation (CyQUANT), invasion (Matrigel transwell assay), and VEGF production (Western blotting, ELISA) were assessed. The small molecule STAT3 inhibitor LLL3 was used to investigate the impact of STAT3 inhibition following OSM stimulation of OSA cells. Our data demonstrate that the OSM receptor (OSMR), but not IL-6 or its receptor, is expressed by all human and canine OSA cell lines and canine OSA tumor samples; additionally, OSM expression was noted in all tumor samples. Treatment of OSA cell lines with OSM induced phosphorylation of STAT3, Src, and JAK2. OSM stimulation also resulted in a dose dependent increase in MMP2 activity and VEGF expression that was markedly reduced following treatment with the small molecule STAT3 inhibitor LLL3. Lastly, OSM stimulation of OSA cell lines enhanced invasion through Matrigel, particularly in the presence of rhHGF. In contrast, both OSM and HGF stimulation of OSA cell lines did not alter their proliferative capacity. These data indicate OSM stimulation of human and canine OSA cells induces STAT3 activation, thereby

  7. Oncostatin M promotes STAT3 activation, VEGF production, and invasion in osteosarcoma cell lines

    Directory of Open Access Journals (Sweden)

    Kisseberth William C

    2011-04-01

    Full Text Available Abstract Background We have previously demonstrated that both canine and human OSA cell lines, as well as 8 fresh canine OSA tumor samples, exhibit constitutive phosphorylation of STAT3, and that this correlates with enhanced expression of matrix metalloproteinase-2 (MMP2. While multiple signal transduction pathways can result in phosphorylation of STAT3, stimulation of the cytokine receptor gp130 through either IL-6 or Oncostatin M (OSM is the most common mechanism through which STAT3 is activated. The purpose of this study was to evaluate the role of IL-6 and OSM stimulation on both canine and human OSA cell lines to begin to determine the role of these cytokines in the biology of OSA. Methods RT-PCR and Western blotting were used to interrogate the consequences of OSM and IL-6 stimulation of OSA cell lines. OSA cells were stimulated with OSM and/or hepatocyte growth factor (HGF and the effects on MMP2 activity (gel zymography, proliferation (CyQUANT, invasion (Matrigel transwell assay, and VEGF production (Western blotting, ELISA were assessed. The small molecule STAT3 inhibitor LLL3 was used to investigate the impact of STAT3 inhibition following OSM stimulation of OSA cells. Results Our data demonstrate that the OSM receptor (OSMR, but not IL-6 or its receptor, is expressed by all human and canine OSA cell lines and canine OSA tumor samples; additionally, OSM expression was noted in all tumor samples. Treatment of OSA cell lines with OSM induced phosphorylation of STAT3, Src, and JAK2. OSM stimulation also resulted in a dose dependent increase in MMP2 activity and VEGF expression that was markedly reduced following treatment with the small molecule STAT3 inhibitor LLL3. Lastly, OSM stimulation of OSA cell lines enhanced invasion through Matrigel, particularly in the presence of rhHGF. In contrast, both OSM and HGF stimulation of OSA cell lines did not alter their proliferative capacity. Conclusions These data indicate OSM stimulation of

  8. Modeling a distributed environment for a petroleum reservoir engineering application with software product line

    International Nuclear Information System (INIS)

    Scheidt, Rafael de Faria; Vilain, Patrícia; Dantas, M A R

    2014-01-01

    Petroleum reservoir engineering is a complex and interesting field that requires large amount of computational facilities to achieve successful results. Usually, software environments for this field are developed without taking care out of possible interactions and extensibilities required by reservoir engineers. In this paper, we present a research work which it is characterized by the design and implementation based on a software product line model for a real distributed reservoir engineering environment. Experimental results indicate successfully the utilization of this approach for the design of distributed software architecture. In addition, all components from the proposal provided greater visibility of the organization and processes for the reservoir engineers

  9. Modeling a distributed environment for a petroleum reservoir engineering application with software product line

    Science.gov (United States)

    de Faria Scheidt, Rafael; Vilain, Patrícia; Dantas, M. A. R.

    2014-10-01

    Petroleum reservoir engineering is a complex and interesting field that requires large amount of computational facilities to achieve successful results. Usually, software environments for this field are developed without taking care out of possible interactions and extensibilities required by reservoir engineers. In this paper, we present a research work which it is characterized by the design and implementation based on a software product line model for a real distributed reservoir engineering environment. Experimental results indicate successfully the utilization of this approach for the design of distributed software architecture. In addition, all components from the proposal provided greater visibility of the organization and processes for the reservoir engineers.

  10. Comparison of growth performance and immune parameters of three commercial chicken lines used in organic production.

    Science.gov (United States)

    Kjærup, R B; Juul-Madsen, H R; Norup, L R; Sørensen, P; Dalgaard, T S

    2017-05-01

    Owing to the higher demands for avoiding medication and antibiotics, health status of the production animals plays an important role in the poultry industry, especially in organic poultry systems. Immunity plays a major role in keeping the host free from disease, and it is evident that the host's genetic make-up influences immunity and disease resistance/susceptibility in chickens. Previously, breeding strategies aimed at selection for resistance against specific diseases with the risk of creating less disease resistance against other pathogens. Changing breeding strategies towards selection of chickens with a more general and broad disease resistance or robustness may therefore improve the overall health status, animal welfare, and food security in the poultry production. The aim of this study was therefore to compare the immunocompetence of the presumed "robust" Hellevad chickens with two chicken lines widely used in organic production, Bovans Brown (Bovans) and Hisex White (Hisex). The chickens were subjected to a routine vaccination program comprising one parasite and four viral vaccines. The current study indicates that considerable differences in immunocompetence may exist between commercial layer lines used in organic production. The Hellevad chickens were found to have higher body weight at the end of the experiment (17 weeks of age) than the other two lines. Furthermore, Hellevad and Hisex chickens were found to have higher levels of humoral innate immunity with regard to sample to positive ratio of natural antibodies in serum and concentration of mannose-binding lectin in serum as compared to Bovans. Moreover, indications of an inflammatory response were observed in the Bovans at week 5, corresponding to 1 week after vaccination with live infectious bursal disease virus. With regard to adaptive immune parameters such as IgY concentration in blood and infectious bursal disease virus (IBDV)-specific antibody titres, the Hellevad and Hisex chickens had lower

  11. Fully Employing Software Inspections Data

    Science.gov (United States)

    Shull, Forrest; Feldmann, Raimund L.; Seaman, Carolyn; Regardie, Myrna; Godfrey, Sally

    2009-01-01

    Software inspections provide a proven approach to quality assurance for software products of all kinds, including requirements, design, code, test plans, among others. Common to all inspections is the aim of finding and fixing defects as early as possible, and thereby providing cost savings by minimizing the amount of rework necessary later in the lifecycle. Measurement data, such as the number and type of found defects and the effort spent by the inspection team, provide not only direct feedback about the software product to the project team but are also valuable for process improvement activities. In this paper, we discuss NASA's use of software inspections and the rich set of data that has resulted. In particular, we present results from analysis of inspection data that illustrate the benefits of fully utilizing that data for process improvement at several levels. Examining such data across multiple inspections or projects allows team members to monitor and trigger cross project improvements. Such improvements may focus on the software development processes of the whole organization as well as improvements to the applied inspection process itself.

  12. Production of neutron deficient rare isotope beams at IGISOL; on-line and off-line studies

    NARCIS (Netherlands)

    Huikari, J; Dendooven, P; Jokinen, A; Nieminen, A; Penttila, H; Perajarvi, K; Popov, A; Rinta-Antila, S; Aysto, J

    This article reports on recent on-line yield measurements employing the light-ion and heavy-ion reaction-based ion guide systems and new results on a-recoil ion transport properties in ion guides with and without electric fields. In addition, the presently used ion guide designs for fusion

  13. Assembly-line health check up in digitalized hospital.

    Science.gov (United States)

    Liu, Yalan; Yao, Bin; Zhang, Zigang

    2002-01-01

    The health check up flow of digital hospital can be consulted with the assembly line of industry factory. Because they have the following same features: highly specialized workstation, closeness and continuance, rhythm, balanced production, continuous production. The essential prerequisites are as the follows: The inspecting items and methods should be stable; advanced product mix and stable production design; standardized raw material, consumption, procedure, inspection method; there are lots of request for health inspection; the customers move at the least unit; the space arrangement should be reasonable; the time arrangement should be proportion. With the computer net, the digital inspection can achieves the raw material controlling accurately. The basis of check up line concerns about equipment, net and software, data collection, and personnel. The group technology is used in the health inspection flow design of the digital hospital in the field of items customers and zone redivided. The digital assembly linemic health inspect has the following stages: member registering, notice, check in, arrange order, time control, report, feedback and analysis. The assembly linemic has following advantages: increasing the productivity, the space utility, satisfaction of customer, fund returning, lowering the cost and ensuring the quality.

  14. Nuclear Energy Research Initiative Project No. 02 103 Innovative Low Cost Approaches to Automating QA/QC of Fuel Particle Production Using On Line Nondestructive Methods for Higher Reliability Final Project Report

    Energy Technology Data Exchange (ETDEWEB)

    Ahmed, Salahuddin; Batishko, Charles R.; Flake, Matthew; Good, Morris S.; Mathews, Royce; Morra, Marino; Panetta, Paul D.; Pardini, Allan F.; Sandness, Gerald A.; Tucker, Brian J.; Weier, Dennis R.; Hockey, Ronald L.; Gray, Joseph N.; Saurwein, John J.; Bond, Leonard J.; Lowden, Richard A.; Miller, James H.

    2006-02-28

    This Nuclear Energy Research Initiative (NERI) project was tasked with exploring, adapting, developing and demonstrating innovative nondestructive test methods to automate nuclear coated particle fuel inspection so as to provide the United States (US) with necessary improved and economical Quality Assurance and Control (QA/QC) that is needed for the fuels for several reactor concepts being proposed for both near term deployment [DOE NE & NERAC, 2001] and Generation IV nuclear systems. Replacing present day QA/QC methods, done manually and in many cases destructively, with higher speed automated nondestructive methods will make fuel production for advanced reactors economically feasible. For successful deployment of next generation reactors that employ particle fuels, or fuels in the form of pebbles based on particles, extremely large numbers of fuel particles will require inspection at throughput rates that do not significantly impact the proposed manufacturing processes. The focus of the project is nondestructive examination (NDE) technologies that can be automated for production speeds and make either: (I) On Process Measurements or (II) In Line Measurements. The inspection technologies selected will enable particle “quality” qualification as a particle or group of particles passes a sensor. A multiple attribute dependent signature will be measured and used for qualification or process control decisions. A primary task for achieving this objective is to establish standard signatures for both good/acceptable particles and the most problematic types of defects using several nondestructive methods.

  15. Comparisons of NDT Methods to Inspect Cork and Cork filled Epoxy Bands

    Science.gov (United States)

    Lingbloom, Mike

    2007-01-01

    Sheet cork and cork filled epoxy provide external insulation for the Reusable Solid Rocket Motor (RSRM) on the Nation's Space Transportation System (STS). Interest in the reliability of the external insulation bonds has increased since the Columbia incident. A non-destructive test (NDT) method that will provide the best inspection for these bonds has been under evaluation. Electronic Shearography has been selected as the primary NDT method for inspection of these bond lines in the RSRM production flow. ATK Launch Systems Group has purchased an electronic shearography system that includes a vacuum chamber that is used for evaluation of test parts and custom vacuum windows for inspection of full-scale motors. Although the electronic shearography technology has been selected as the primary method for inspection of the external bonds, other technologies that exist continue to be investigated. The NASA/Marshall Space Flight Center (MSFC) NDT department has inspected several samples for comparison with electronic shearography with various inspections systems in their laboratory. The systems that were evaluated are X-ray backscatter, terahertz imaging, and microwave imaging. The samples tested have some programmed flaws as well as some flaws that occurred naturally during the sample making process. These samples provide sufficient flaw variation for the evaluation of the different inspection systems. This paper will describe and compare the basic functionality, test method and test results including dissection for each inspection technology.

  16. Important updates introduced by the new regulation on the industrial and sanitary inspection of products of animal origin: Decree no. 9.013 of March 29, 2017

    Directory of Open Access Journals (Sweden)

    João Modesto Júnior

    2017-11-01

    Full Text Available Introduction: Various legal devices regulate the food hygiene inspections of animals origin in Brazil. Among the most important legislation was Decree no. 30,691, of March 29, 1952, which was replaced on March 29, 2017, by Decree no. 9,013. Objective: Thus, considering the relevant importance of this regulation for national agribusiness and consumer health, the present work aimed to evaluate the updates and changes of the new regulation in comparison to its predecessor. Method: For this purpose, a revision of the legislation on health inspection published by the federal government was carried out, through the search of databases in federal government portals for a better understanding of the subject and as a comparative form. Results: The new regulation is less robust than its previous one, presenting 542 articles. The main updates innovations were the insertion of degrees of risk in establishments, simplification of labels and stamps, more modern laboratorial analysis such as molecular biology, distinction of requirements according to the size of production, more severe penalties for companies which break the law, concern for animal welfare and the environment. Conclusions: In this way, updating the regulation was necessary, and brought important innovations with modern concepts, new technological processes and food safety, better suited to the current reality of Brazil.

  17. Natural products from Cuscuta reflexa Roxb. with antiproliferation activities in HCT116 colorectal cell lines.

    Science.gov (United States)

    Riaz, Muhammad; Bilal, Aishah; Ali, Muhammad Shaiq; Fatima, Itrat; Faisal, Amir; Sherkheli, Muhammad Azhar; Asghar, Adnan

    2017-03-01

    Parasitic Cuscuta reflexa Roxb. possesses many medicinal properties and is a rich source of a variety of biologically relevant natural products. Natural products are the prime source of leads, drugs, and drug templates, and many of the anticancer and antiviral drugs are either based on natural product or derived from them. Cancer is a devastating disease and one of the leading causes of death worldwide despite improvements in patient survival during the past 50 years; new and improved treatments for cancer are therefore actively sought. Colorectal cancer is the fourth most prevalent cancer worldwide and is responsible for nearly 9% of all cancer deaths. Our search for anticancer natural products from C. reflexa has yielded four natural products: Scoparone (1), p-coumaric acid (2), stigmasta-3,5-diene (3) and 1-O-p-hydroxycinnamoylglucose (4) and among them 1-O-p-hydroxycinnamoyldlucose (4) showed promising antiproliferative activities in HCT116 colorectal cell lines, whereas compounds 1-3 showed moderate activities.

  18. 9 CFR 312.2 - Official marks and devices to identify inspected and passed products of cattle, sheep, swine, or...

    Science.gov (United States)

    2010-01-01

    ..., and the smaller varieties of sausage and meat food products in animal casings. EC11SE91.001 For application to calf and goat carcasses and on the larger varieties of sausage and meat food products in animal... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Official marks and devices to identify...

  19. Automated inspection of gaps on the free-form shape parts by laser scanning technologies

    Science.gov (United States)

    Zhou, Sen; Xu, Jian; Tao, Lei; An, Lu; Yu, Yan

    2018-01-01

    In industrial manufacturing processes, the dimensional inspection of the gaps on the free-form shape parts is critical and challenging, and is directly associated with subsequent assembly and terminal product quality. In this paper, a fast measuring method for automated gap inspection based on laser scanning technologies is presented. The proposed measuring method consists of three steps: firstly, the relative position is determined according to the geometric feature of measuring gap, which considers constraints existing in a laser scanning operation. Secondly, in order to acquire a complete gap profile, a fast and effective scanning path is designed. Finally, the range dimension of the gaps on the free-form shape parts including width, depth and flush, correspondingly, is described in a virtual environment. In the future, an appliance machine based on the proposed method will be developed for the on-line dimensional inspection of gaps on the automobile or aerospace production line.

  20. Fission product nuclear data obtained by use of an on-line mass spectrometer

    International Nuclear Information System (INIS)

    Reeder, P.L.; Wright, J.F.; Anderl, R.A.

    1975-01-01

    A Spectrometer for On-Line Analysis of Radionuclides (SOLAR) has been installed at a 1 MW TRIGA reactor at Washington State University. Fission product ions from a combination target/ion source located within the thermal column are brought out to a 60 0 magnetic sector mass spectrometer. Surface ionization provides copious beams of Rb + and Cs + ions and less intense beams of Br - and I - ions with negligible contamination by other elements. About 40 fission product nuclides can thus be chemically and physically separated in times of less than 1 second. Past results on independent and cumulative fission yields along with measurements of half-lives of some very neutron-rich nuclides are presented. Current work on delayed-neutron emission probabilities and energy spectra of delayed neutrons from individual nuclides is described. (7 tables, 2 figures) (U.S.)

  1. Thin blue lines: product placement and the drama of pregnancy testing in British cinema and television.

    Science.gov (United States)

    Olszynko-Gryn, Jesse

    2017-09-01

    This article uses the case of pregnancy testing in Britain to investigate the process whereby new and often controversial reproductive technologies are made visible and normalized in mainstream entertainment media. It shows how in the 1980s and 1990s the then nascent product placement industry was instrumental in embedding pregnancy testing in British cinema and television's dramatic productions. In this period, the pregnancy-test close-up became a conventional trope and the thin blue lines associated with Unilever's Clearblue rose to prominence in mainstream consumer culture. This article investigates the aestheticization of pregnancy testing and shows how increasingly visible public concerns about 'schoolgirl mums', abortion and the biological clock, dramatized on the big and small screen, propelled the commercial rise of Clearblue. It argues that the Clearblue close-up ambiguously concealed as much as it revealed; abstraction, ambiguity and flexibility were its keys to success.

  2. Comparison of growth performance and immune parameters of three commercial chicken lines used in organic production

    DEFF Research Database (Denmark)

    Kjærup, Rikke Brødsgaard; Juul-Madsen, Helle Risdahl; Norup, Liselotte Rothmann

    2017-01-01

    ’s genetic make-up influences immunity and disease resistance/susceptibility in chickens. Previously, breeding strategies aimed at selection for resistance against specific diseases with the risk of creating less disease resistance against other pathogens. Changing breeding strategies towards selection...... of chickens with a more general and broad disease resistance or robustness may therefore improve the overall health status, animal welfare, and food security in the poultry production. The aim of this study was therefore to compare the immunocompetence of the presumed “robust” Hellevad chickens with two...... chicken lines widely used in organic production, Bovans Brown (Bovans) and Hisex White (Hisex). The chickens were subjected to a routine vaccination program comprising one parasite and four viral vaccines. The current study indicates that considerable differences in immunocompetence may exist between...

  3. Lipogenesis and glucose production in dwarf carrier and normal lines of chicks

    International Nuclear Information System (INIS)

    Rosebrough, R.W.; McMurtry, J.P.; Steele, N.C.

    1986-01-01

    Diets containing 13, 16, 19, or 23% protein and 70% carbohydrate calories were fed to dwarf heterozygote (dw) and normal (Dw) chickens to determine the effects of age (weeks) and protein on intermediary metabolism. In vitro lipogenesis (IVL) was determined by the incorporation of acetate (10 and 20 mM 2 14 C-Acet/2hr) into hepatic fatty acids. Net glucose production (NGP) was determined as the difference in media glucose in the presence or absence of 10 mM pyruvate. Values were expressed per unit of relative liver size (μmoles/100 g BWt). Serum insulin (INS; ng/ml) was determined by homologous radioimmunoassay. Results indicate that although INS was greater in Dw than in dw, this difference was not reflected in a decreased rate of glucose production to accompany the difference in IVL between the two lines. Moreover, an increase in dietary protein resulted in a decrease in IVL but an increase in INS

  4. A prototype on-line work procedure system for radioisotope thermoelectric generator production

    International Nuclear Information System (INIS)

    Kiebel, G.R.

    1991-09-01

    An on-line system to manage work procedures is being developed to support radioisotope thermoelectric generator (RTG) assembly and testing in a new production facility. This system implements production work procedures as interactive electronic documents executed at the work site with no intermediate printed form. It provides good control of the creation and application of work procedures and provides active assistance to the worker in performing them and in documenting the results. An extensive prototype of this system is being evaluated to ensure that it will have all the necessary features and that it will fit the user's needs and expectations. This effort has involved the Radioisotope Power Systems Facility (RPSF) operations organization and technology transfer between Westinghouse Hanford Company (Westinghouse Hanford) and EG ampersand G Mound Applied Technologies Inc. (Mound) at the US Department of Energy (DOE) Mound Site. 1 ref

  5. Analysis of cell line variation in biochemical production of protoporphyrin IX

    Science.gov (United States)

    Gibbs, Summer L.; Chen, Bin; O'Hara, Julia A.; Hoopes, P. Jack; Hasan, Tayyaba; Pogue, Brian W.

    2006-02-01

    Protoporphyrin IX (PpIX) is produced via the heme synthesis pathway by the cell following administration of aminolevulinic acid (ALA). ALA synthase, the enzyme that produces ALA in the cell from glycine and succinyl-coenzyme A, is inhibited in a feedback mechanism by heme and thus is the rate limiting enzyme in the heme synthesis pathway. Since ALA is administered systemically, the rate limiting step that naturally exists in the cells is bypassed, however it is currently unclear why cells have different rate limiting steps in the ALA-PpIX synthesis pathway, and more specifically which types of cancer cells are most productive. It has been determined that when the same amount of ALA is administered to a wide panel of cancer cells in vitro that vastly differing amounts of PpIX are produced. The steps for the ALA-PpIX pathway occur in and around the mitochondria of the cell, but interestingly no correlation is seen between PpIX production and mitochondrial content of the cell, following ALA administration. However, total cell area shows positive correlation with PpIX production. Administration of the iron chelator, 1,2-dimethyl-3-hydroxy-4-pyridone (L1) in combination with ALA allows the final step in the heme synthesis pathway, conversion of PpIX to heme, to be delayed and thus increases the detectable amount of PpIX in each cell line. The cell lines that have the lowest PpIX production following administration of ALA alone show the largest increase in production following the combined administration of ALA and L1. PpIX fluorescence is thought to be a measure of cellular activity and the goal of the current study was to determine which cell lines would be the most promising targets for fluorescence detection or monitoring response to therapy. The results indicate that the cells with larger size and larger numbers of mitochondria may be good potential targets for this therapy. While this conclusion may appear obvious, it is not universally true, and cellular specific

  6. Methodology supporting production control in a foundry applying modern DISAMATIC molding line

    Directory of Open Access Journals (Sweden)

    Sika Robert

    2017-01-01

    Full Text Available The paper presents methodology of production control using statistical methods in foundry conditions, using the automatic DISAMATIC molding line. The authors were inspired by many years of experience in implementing IT tools for foundries. The authors noticed that there is a lack of basic IT tools dedicated to specific casting processes, that would greatly facilitate their oversight and thus improve the quality of manufactured products. More and more systems are installed in the ERP or CAx area, but they integrate processes only partially, mainly in the area of technology design and business management from finance and control. Monitoring of foundry processes can generate a large amount of process-related data. This is particularly noticeable in automated processes. An example is the modern DISAMATIC molding line, which integrates several casting processes, such as mold preparation, assembly, pouring or shake out. The authors proposed a methodology that supports the control of the above-mentioned foundry processes using statistical methods. Such an approach can be successfully used, for example, during periodic external audits. The mentioned methodology in the innovative DISAM-ProdC computer tool was implemented.

  7. 75 FR 38765 - Domestic Origin Verification System Questionnaire and Regulations Governing Inspection and...

    Science.gov (United States)

    2010-07-06

    ..., facility assessment services, certifications of quantity and quality, import product inspections, and... control number. These include export certification, inspection of section 8e import products, and...] Domestic Origin Verification System Questionnaire and Regulations Governing Inspection and Certification of...

  8. 40 CFR 1045.320 - What happens if one of my production-line engines fails to meet emission standards?

    Science.gov (United States)

    2010-07-01

    ...-line engines fails to meet emission standards? 1045.320 Section 1045.320 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM SPARK-IGNITION PROPULSION MARINE ENGINES AND VESSELS Testing Production-line Engines § 1045.320 What happens if one of my...

  9. 9 CFR 381.38 - Overtime and holiday inspection service.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Overtime and holiday inspection... Inspection; Overtime and Holiday Service; Billing Establishments § 381.38 Overtime and holiday inspection... Program, at the rate specified in § 391.3, for the cost of the inspection service furnished on any holiday...

  10. Critical care medicine as a distinct product line with substantial financial profitability: the role of business planning.

    Science.gov (United States)

    Bekes, Carolyn E; Dellinger, R Phillip; Brooks, Daniel; Edmondson, Robert; Olivia, Christopher T; Parrillo, Joseph E

    2004-05-01

    As academic health centers face increasing financial pressures, they have adopted a more businesslike approach to planning, particularly for discrete "product" or clinical service lines. Since critical care typically has been viewed as a service provided by a hospital, and not a product line, business plans have not historically been developed to expand and promote critical care. The major focus when examining the finances of critical care has been cost reduction, not business development. We hypothesized that a critical care business plan can be developed and analyzed like other more typical product lines and that such a critical care product line can be profitable for an institution. In-depth analysis of critical care including business planning for critical care services. Regional academic health center in southern New Jersey. None. As part of an overall business planning process directed by the Board of Trustees, the critical care product line was identified by isolating revenue, expenses, and profitability associated with critical care patients. We were able to identify the major sources ("value chain") of critical care patients: the emergency room, patients who are admitted for other problems but spend time in a critical care unit, and patients transferred to our intensive care units from other hospitals. The greatest opportunity to expand the product line comes from increasing the referrals from other hospitals. A methodology was developed to identify the revenue and expenses associated with critical care, based on the analysis of past experience. With this model, we were able to demonstrate a positive contribution margin of dollar 7 million per year related to patients transferred to the institution primarily for critical care services. This can be seen as the profit related to the product line segment of critical care. There was an additional positive contribution margin of dollar 5.8 million attributed to the critical care portion of the hospital stay of

  11. Common display performance requirements for military and commercial aircraft product lines

    Science.gov (United States)

    Hoener, Steven J.; Behrens, Arthur J.; Flint, John R.; Jacobsen, Alan R.

    2001-09-01

    Obtaining high quality Active Matrix Liquid Crystal (AMLCD) glass to meet the needs of the commercial and military aerospace business is a major challenge, at best. With the demise of all domestic sources of AMLCD substrate glass, the industry is now focused on overseas sources, which are primarily producing glass for consumer electronics. Previous experience with ruggedizing commercial glass leads to the expectation that the aerospace industry can leverage off the commercial market. The problem remains, while the commercial industry is continually changing and improving its products, the commercial and military aerospace industries require stable and affordable supplies of AMLCD glass for upwards of 20 years to support production and maintenance operations. The Boeing Engineering and Supplier Management Process Councils have chartered a group of displays experts from multiple aircraft product divisions within the Boeing Company, the Displays Process Action Team (DPAT), to address this situation from an overall corporate perspective. The DPAT has formulated a set of Common Displays Performance Requirements for use across the corporate line of commercial and military aircraft products. Though focused on the AMLCD problem, the proposed common requirements are largely independent of display technology. This paper describes the strategy being pursued within the Boeing Company to address the AMLCD supply problem and details the proposed implementation process, centered on common requirements for both commercial and military aircraft displays. Highlighted in this paper are proposed common, or standard, display sizes and the other major requirements established by the DPAT, along with the rationale for these requirements.

  12. Methodology if inspections to carry out the nuclear outages model

    International Nuclear Information System (INIS)

    Aycart, J.; Mortenson, S.; Fourquet, J. M.

    2005-01-01

    Before the nuclear generation industry was deregulated in the United States, refueling and maintenance outages in nuclear power plants usually lasted orotund 100 days. After deregulation took effect, improved capability factors and performances became more important. As a result, it became essential to reduce the critical path time during the outage, which meant that activities that had typically been done in series had to be executed in parallel. The new outage model required the development of new tools and new processes, The 360-degree platform developed by GE Energy has made it possible to execute multiple activities in parallel. Various in-vessel visual inspection (IVVI) equipments can now simultaneously perform inspections on the pressurized reactor vessel (RPV) components. The larger number of inspection equipments in turn results in a larger volume of data, with the risk of increasing the time needed for examining them and postponing the end of the analysis phase, which is critical for the outage. To decrease data analysis times, the IVVI Digitalisation process has been development. With this process, the IVVI data are sent via a high-speed transmission line to a site outside the Plant called Center of Excellence (COE), where a team of Level III experts is in charge of analyzing them. The tools for the different product lines are being developed to interfere with each other as little as possible, thus minimizing the impact of the critical path on plant refueling activities. Methods are also being developed to increase the intervals between inspection. In accordance with the guidelines of the Boiling Water Reactor Vessel and Internals project (BWRVIP), the intervals between inspections are typically longer if ultrasound volumetric inspections are performed than if the scope is limited to IVVI. (Author)

  13. Effect of Inspection Policies and Residual Value of Collected Used Products: A Mathematical Model and Genetic Algorithm for a Closed-Loop Green Manufacturing System

    Directory of Open Access Journals (Sweden)

    Byung Duk Song

    2017-09-01

    Full Text Available In the green manufacturing system that pursues the reuse of used products, the residual value of collected used products (CUP hugely affects a variety of managerial decisions to construct profitable and environmental remanufacturing plans. This paper deals with a closed-loop green manufacturing system for companies which perform both manufacturing with raw materials and remanufacturing with collected used products (CUP. The amount of CUP is assumed as a function of buy-back cost while the quality level of CUP, which means the residual value, follows a known distribution. In addition, the remanufacturing cost can differ according to the quality of the CUP. Moreover, nowadays companies are subject to existing environment-related laws such as Extended Producer Responsibility (EPR. Therefore, a company should collect more used products than its obligatory take-back quota or face fines from the government for not meeting its quota. Through the development of mathematical models, two kinds of inspection policies are examined to validate the efficiency of two different operation processes. To find a managerial solution, a genetic algorithm is proposed and tested with numerical examples.

  14. Advances based on digital technology named TEDDY+ for inspection of eddy current

    International Nuclear Information System (INIS)

    Barcenilla, V.; Hernandez, J.; Ribes, B.

    2007-01-01

    As a result of the recent developing line of eddy current data acquisition system a new product based on digital technology named TEDDY+, comes to the market. With only 4 kg of weight constitutes a great advance with regards to other equipment's available in the market. These advances, have enabled, among others, to increase considerably the signal to noise (S/N) ratio, avoid typical saturation problems in the eddy current signal, increase the inspection speed, eliminate the reference probe, detect the air/tube signal in real time, and the possibility to integrate the tester inside a push puller thanks to its reduced size and to have integrated as part of the ET equipment the mechanical systems control board. Two product lines have been developed, one oriented to any market and application (nuclear market, industrial and aeronautical, chemical and petrochemical, etc) and other specially dedicated to the massive inspection of tubes, named TEDDY+SP (Suitcase Pusher). Both lines are prepared to use eddy current arrays which clearly constitute the future of the eddy current inspection systems. The new TEDDY+ line of products presented in this paper constitutes one of the most powerful and reliable existing in the market. These improvements and novelties place the new ET inspection system from Tecnatom as one of the most powerful and reliable in the market. (Author)

  15. RBI - Risk Based Inspection: new technologies and methods applied to inspections of FPSO (Floating Production, Storage and Offloading Vessel) hull; IBR - Inspecao Baseada em Risco: novas tecnologias e metodos aplicados as inspecoes de casco de FPSOs

    Energy Technology Data Exchange (ETDEWEB)

    Farias, Bruno de; Figueiredo, Eduardo; Luiz, Marcio [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil); Meurer, Gustavo; Duarte, Romulo; Oliveira, Thais; Krzonkalla, Viviane [ABS Consulting, Rio de Janeiro, RJ (Brazil)

    2008-07-01

    With the aging of the FPSO's, which are fundamental to the operation Offshore, better techniques and technologies must be applied to assess more accurately the actual efficiency and structural conditions of producing unit. With the emergence of new engineering techniques and equipment and methods of structural inspection, is now possible to use these new technologies to better manage risk and reliability of the structure of the FPSO, with that, the inspections and methods are more rational and efficient. The Risk-Based Inspection is the tool for monitoring operation of industrial plants with systemic use of technology in conjunction with risk analysis and reliability. His concept is applicable to various branches of industry. The companies began their implementation of oil by refineries. The group of ABS Consulting with PETROBRAS has been developing and implementing these new technologies in inspections of hulls of FPSO's. Applied successfully in the units of the Campos basin, these methods are used by the group of Risk-Based Inspection to improve the efficiency of all the steps involved with the structural integrity of the unit. (author)

  16. Development of a plug-in for Variability Modeling in Software Product Lines

    Directory of Open Access Journals (Sweden)

    María Lucía López-Araujo

    2012-03-01

    Full Text Available Las Líneas de Productos de Software (LPS toman ventaja económica de las similitudes y variación entre un conjunto de sistemas de software dentro de un dominio específico. La Ingeniería de Líneas de Productos de Software por lo tanto, define una serie de procesos para el desarrollo de LPS que consideran las similitudes y variación a lo largo del ciclo devida. El modelado de variabilidad, en consecuencia, es una actividad esencial en un enfoque de Ingeniería de Líneas de Productos de Software. Existen varias técnicas para modelado de variabilidad. Entre ellas resalta COVAMOF que permite modelar los puntos de variación, variantes y dependencias como entidades de primera clase, proporcionando una manera uniforme de representarlos en los diversos niveles de abstracción de una LPS. Para poder aprovechar los beneficios de COVAMOF es necesario contar con una herramienta, de otra manera el modelado y la administración de la variabilidad pueden resultar una labor ardua para el ingeniero de software. Este trabajo presenta el desarrollo de un plug-in de COVAMOF para Eclipse.Software Product Lines (SPL take economic advantage of commonality and variability among a set of software systems that exist within a specific domain. Therefore, Software Product Line Engineering defines a series of processes for the development of a SPL that consider commonality and variability during the software life cycle. Variability modeling is therefore an essential activity in a Software Product Line Engineering approach. There are several techniques for variability modeling nowadays. COVAMOF stands out among them since it allows the modeling of variation points, variants and dependencies as first class elements. COVAMOF, therefore, provides an uniform manner for representing such concepts in different levels of abstraction within a SPL. In order to take advantage of COVAMOF benefits, it is necessary to have a computer aided tool, otherwise variability modeling and

  17. FEDERAL USERS CONFERENCE PRODUCT LINE TOOL SET (PLTS) MAP PRODUCTION SYSTEM (MPS) ATLAS CUSTOM GRIDS [Rev 0 was draft

    Energy Technology Data Exchange (ETDEWEB)

    HAYENGA, J.L.

    2006-12-19

    Maps, and more importantly Atlases, are assisting the user community in managing a large land area with complex issues, the most complex of which is the management of nuclear waste. The techniques and experiences discussed herein were gained while developing several atlases for use at the US Department of Energy's Hanford Site. The user community requires the ability to locate not only waste sites, but other features as well. Finding a specific waste site on a map and in the field is a difficult task at a site the size of Hanford. To find a specific waste site, the user begins by locating the item or object in an index, then locating the feature on the corresponding map within an atlas. Locating features requires a method for indexing them. The location index and how to place it on a map or atlas is the central theme presented in this article. The user requirements for atlases forced the design team to develop new and innovative solutions for requirements that Product Line Tool Set (PLTS) Map Production System (MPS)-Atlas was not designed to handle. The layout of the most complex atlases includes custom reference grids, multiple data frames, multiple map series, and up to 250 maps. All of these functional requirements are at the extreme edge of the capabilities of PLTS MPS-Atlas. This document outlines the setup of an atlas using PLTS MPS-Atlas to meet these requirements.

  18. FEDERAL USERS CONFERENCE PRODUCT LINE TOOL SET (PLTS) MAP PRODUCTION SYSTEM (MPS) ATLAS CUSTOM GRIDS [Rev 0 was draft

    International Nuclear Information System (INIS)

    HAYENGA, J.L.

    2006-01-01

    Maps, and more importantly Atlases, are assisting the user community in managing a large land area with complex issues, the most complex of which is the management of nuclear waste. The techniques and experiences discussed herein were gained while developing several atlases for use at the US Department of Energy's Hanford Site. The user community requires the ability to locate not only waste sites, but other features as well. Finding a specific waste site on a map and in the field is a difficult task at a site the size of Hanford. To find a specific waste site, the user begins by locating the item or object in an index, then locating the feature on the corresponding map within an atlas. Locating features requires a method for indexing them. The location index and how to place it on a map or atlas is the central theme presented in this article. The user requirements for atlases forced the design team to develop new and innovative solutions for requirements that Product Line Tool Set (PLTS) Map Production System (MPS)-Atlas was not designed to handle. The layout of the most complex atlases includes custom reference grids, multiple data frames, multiple map series, and up to 250 maps. All of these functional requirements are at the extreme edge of the capabilities of PLTS MPS-Atlas. This document outlines the setup of an atlas using PLTS MPS-Atlas to meet these requirements

  19. Excision of foreign gene product with cathepsin D in chicken hepatoma cell line

    International Nuclear Information System (INIS)

    Sato, Masaharu; Kawashima, Tsuyoshi; Aosasa, Masayoshi; Horiuchi, Hiroyuki; Furusawa, Shuichi; Matsuda, Haruo

    2005-01-01

    To easily and rapidly recover exogenous gene products from chicken egg yolk, we constructed pVTG-catD (VTG, vitellogenin; catD, cathepsin D), a vector cassette carrying two catD-recognition signal peptides (catD-RSPs) in addition to the cloning site. An enhanced green fluorescence protein (EGFP)-encoding DNA fragment was ligated into the pVTG-catD. When the resultant construct pVTG-EGFP-catD containing histidine- and myc-tags was transfected into the chicken hepatoma cell line LMH, EGFP-expression at 24 h post-cultivation was confirmed by fluorescence microscopy. Because a signal peptide (NTVLAEF) encoded in pVTG-EGFP-catD is recognized by catD, the VTG-EGFP fusion protein digested with catD was detectable by Western blotting. Digested exogenous gene product was recovered with nickel resin. These results indicate that catD-recognition sites bearing pVTG-catD and His-tags are functional in chicken LMH cells. Therefore, the system described here may be of use in making excision exogenous gene products in the chicken and in creating homozygous knock-in chickens

  20. Effect of selection for productive traits in broiler maternal lines on embryo development

    Directory of Open Access Journals (Sweden)

    Schmidt GS

    2003-01-01

    Full Text Available This study used 300 females and 30 males with 36 weeks of age from the selected PP and control PPc maternal broiler lines. PP has been selected for heavy body weight (PC and high egg production for eight generations. Fertile eggs were collected and weighed individually for 4 periods of 5 consecutive days at two-week intervals. In each period, a total of 960 eggs/line were identified and separated in groups of 240 eggs, and stored for later incubation. Embryo weight (PE was evaluated at 9 (P9, 11 (P11, 13 (P13, 15 (P15, 17 (P17 and 21 (P21 days of incubation. The objective was to estimate the effect of selection on embryo development. Egg weight (PO was similar between the two lines. The differences in PE were significant from P15 on, resulting in 1.9g of difference in the chick weight, indicating correlated genetic changes in the embryo development, which can be credited to the selection for PC. Changes in PE while PO was kept unaltered modified the correlations between these two traits. Differences were significant from P13 on and estimated correlations for P21 were 0.72 and 0.70 for PP and PPc, respectively. Chick weight corresponded to 70.91% (PP and 68.48% (PPc of egg weight. The estimated increase in P21 that resulted from the increase of 1.0g in PO was 0.71 in PP and 0.68g in PPc.

  1. Optimal Scheduling of Material Handling Devices in a PCB Production Line: Problem Formulation and a Polynomial Algorithm

    Directory of Open Access Journals (Sweden)

    Ada Che

    2008-01-01

    Full Text Available Modern automated production lines usually use one or multiple computer-controlled robots or hoists for material handling between workstations. A typical application of such lines is an automated electroplating line for processing printed circuit boards (PCBs. In these systems, cyclic production policy is widely used due to large lot size and simplicity of implementation. This paper addresses cyclic scheduling of a multihoist electroplating line with constant processing times. The objective is to minimize the cycle time, or equivalently to maximize the production throughput, for a given number of hoists. We propose a mathematical model and a polynomial algorithm for this scheduling problem. Computational results on randomly generated instances are reported.

  2. Factors associated with regulatory action involving investigation of illnesses associated with Shiga toxin-producing Escherichia coli in products regulated by the Food Safety and Inspection Service.

    Science.gov (United States)

    Green, Alice L; Seys, Scott; Douris, Aphrodite; Levine, Jeoff; Robertson, Kis

    2014-07-01

    We described characteristics of the Escherichia coli O157 and Escherichia coli non-O157 illness investigations conducted by the United States Department of Agriculture's Food Safety and Inspection Service (FSIS) during the 5-year period from 2006 through 2010. We created a multivariable logistic regression model to determine characteristics of these investigations that were associated with FSIS regulatory action, which was defined as having occurred if a product recall occurred or if FSIS personnel performed an environmental health assessment (Food Safety Assessment) at the implicated establishment. During this period, FSIS took regulatory action in 38 of 88 (43%) investigations. Illness investigations in which FoodNet states were involved were more likely to result in regulatory action. Illness investigations in which state and local traceback, or FSIS traceback occurred were more likely to result in regulatory action. Reasons for lack of action included evidence of cross-contamination after the product left a regulated establishment, delayed notification, lack of epidemiological information, and insufficient product information.

  3. Exponentiation for products of Wilson lines within the generating function approach

    International Nuclear Information System (INIS)

    Vladimirov, A.A.

    2015-01-01

    We present the generating function approach to the perturbative exponentiation of correlators of a product of Wilson lines and loops. The exponentiated expression is presented in closed form as an algebraic function of correlators of known operators, which can be seen as a generating function for web diagrams. The expression is naturally split onto two parts: the exponentiation kernel, which accumulates all non-trivial information about web diagrams, and the defect of exponentiation, which reconstructs the matrix exponent and is a function of the exponentiation kernel. The detailed comparison of the presented approach with existing approaches to exponentiation is presented as well. We also give examples of calculations within the generating function exponentiation, namely, we consider different configurations of light-like Wilson lines in the multi-gluon-exchange-webs (MGEW) approximation. Within this approximation the corresponding correlators can be calculated exactly at any order of perturbative expansion by only algebraic manipulations. The MGEW approximation shows violation of the dipole formula for infrared singularities at three-loop order.

  4. Interleukin-2 production by human leukemia cell lines of pre-B cell origin

    International Nuclear Information System (INIS)

    Holan, V.; Minowada, J.

    1993-01-01

    Cells of 7 tested human leukemia cell lines of pre-B cell origin (as characterized by immunophenotyping and by the expression of cytoplasmic micro chains, but not by surface immunoglobulins) produced after stimulation with bacterial lipopolysaccharide (LPS) or phorbol myristate acetate (PMA) a lymphokine activity which supported the growth of the interleukin-2 (IL-2)-dependent CTLL-2 cell line. Three pieces of evidence indicate that the secreted lymphokine was functionally and antigenically very similar, if not identical, to human IL-2: (1) The lymphokine supported the growth of murine IL-2-dependent CTLL-2 cells, which did not respond to human lymphokines other than IL-2, but it did not stimulate the growth of murine IL-3-dependent FDC-P2 cells, (2) the biological activity of the lymphokine was was inhibited by monoclonal antibody (mAb) anti-human-IL-2, and (3) the proliferation of IL-2-dependent cells in the presence of the active materials was completely inhibited by the inclusion of the anti-mouse-IL-2 receptor (IL-2R) mAb. Since leukemia cells of immature B-cell origin also synthesize IL-2R, the human pre-B cell leukemias could represent another type of hematological malignancy where the autocrine processes of IL-2 production and utilization are involved in the expansion of the disease. (author)

  5. Supergravity couplings to Noncommutative Branes, Open Wilson Lines and Generalised Star Products

    International Nuclear Information System (INIS)

    Das, S.R.; Trivedi, S.P.

    2001-01-01

    Noncommutative gauge theories can be constructed from ordinary U(∞) gauge theories in lower dimensions. Using this construction we identify the operators on noncommutative D-branes which couple to linearized supergravity backgrounds, from a knowledge of such couplings to lower dimensional D-branes with no B field. These operators belong to a class of gauge invariant observables involving open Wilson lines. Assuming a DBI form of the coupling we show, to second order in the gauge potential but to all orders of the noncommutativity parameter, that our proposal agrees with the operator obtained in terms of ordinary gauge fields by considering brane actions in backgrounds and then using the Seiberg-Witten map to rewrite this in terms of noncommutative gauge fields. Our result clarify why a certain commutative but non-associative 'generalized star product' appears both in the expansion of the open Wilson line, as well as in string amplitude computations of open string-closed string couplings. We outline how our procedure can be used to obtain operators in the noncommutative theory which are holographically dual to supergravity modes. (author)

  6. PRODUCTIVITY OF SUGAR BEET LINES AND THEIR CROSSES DEPENDING ON PLOIDITY

    Directory of Open Access Journals (Sweden)

    Andrija Kristek

    2003-12-01

    Full Text Available Five diploid (2n=2x=18 cms lines, 2 tetraploid (2n=4x=36 and 2 diploid pollinators, as well as 10 diploid and 10 triploid (2n=3x=27 sugar beet hybrids, given by the crossing of investigated cms lines and pollinators were investigated in the field trials. Two triploid hybrids, widespread in sugarbeet production, were sown as standards – Os Sana and Iva. The trials were conducted on two localities (Osijek and Đakovo during the two years (2002 and 2003. There was a difference between years in weather conditions and between localities in terms of type and features of soil. First year of the investigation was humid and warm and the second was dry and hot. Osijek locality was characterized by chernozem-meadow type soil and Đakovo by loessial pseudoglei. The best average root yield was achieved between the investigated genotypes by the triploid hybrid 15 (58.09 t/ha and the hybrids 11, 13 and standard 31. As for the content and utilization of sugar, the standard 31 achieved best results (15.15% followed by the standard hybrids 15, 18, 17 and 11. The best sugar yield was achieved by hybrid 15 (7.08 t/ha, followed by hybrids 13, 11, 10 and 18.

  7. Discussion after implementation of possible ergonomics contributions in production lines automation project

    Directory of Open Access Journals (Sweden)

    José Adriano Canton

    2016-11-01

    Full Text Available This paper addresses the issue of work spaces designed based on Activity-Centered Ergonomics. The aim was to reflect on the role of Ergonomics in the design of productive situations in order to anticipate and mitigate the emergence of new constraints. This study was developed using a case study from the packaging industry, where an automated line was implemented to mitigate the injuries suffered as result of the manual system. This article was based on the results of an Ergonomic Work Analysis of the solution implemented, and the subsequent analysis of this design process. It was found that the adopted solution does not have enough leeway for dealing with variations inherent to the process, requiring constant interventions in the operation, by the operators in order to free the line to continue work. It was evident that the adopted solution did not involve the participation of important agents such as the operators and the maintenance crew, giving the project a technical vision that was concerned with eliminating the human factor. The conclusion of this study was that the Ergonomics integrated into the project development favors the collective construction of analysis of the research, and consequently, the development of more effective solutions.

  8. Copper phytoextraction in tandem with oilseed production using commercial cultivars and mutant lines of sunflower.

    Science.gov (United States)

    Kolbas, A; Mench, M; Herzig, R; Nehnevajova, E; Bes, C M

    2011-01-01

    Use of sunflower (Helianthus annuus L.) for Cu phytoextraction and oilseed production on Cu-contaminated topsoils was investigated in afield trial at a former wood preservation site. Six commercial cultivars and two mutant lines were cultivated in plots with and without the addition of compost (5% w/w) and dolomitic limestone (0.2% w/w). Total soil Cu ranged from 163 to 1170 mg kg(-1). In soil solutions, Cu concentration varied between 0.16-0.93 mg L(-1). The amendment increased soil pH, reduced Cu exposure and promoted sunflower growth. Stem length, shoot and capitulum biomasses, seed yield, and shoot and leaf Cu concentrations were measured. At low total soil Cu, shoot Cu mineralomass was higher in commercial cultivars, Le., Salut, Energic, and Countri, whereas competition and shading affected morphological traits of mutants. Based on shoot yield (7 Mg DW ha(-1)) and Cu concentration, the highest removal was 59 g Cu ha(-1). At high total soil Cu, shoot Cu mineralomass peaked for mutants (e.g., 52 g Cu ha(-1) for Mutant 1 line) and cultivars Energic and Countri. Energic seed yield (3.9 Mg air-DW ha(-1)) would be sufficient to produce oil Phenotype traits and shoot Cu removal depended on sunflower types and Cu exposure.

  9. Industrial Production of Therapeutic Proteins: Cell Lines, Cell Culture, and Purification

    Science.gov (United States)

    Zhu, Marie M.; Mollet, Michael; Hubert, Rene S.

    The biotechnology and pharmaceutical industries have seen a recent surge in the development of biological drug products manufactured from engineered mammalian cell lines. Since the hugely successful launch of human tissue plasminogen activator in 1987 and erythropoietin in 1988, the biopharmaceutical market has grown immensely. Global sales in 2003 exceeded US 30 billion.1 Currently, a total of 108 biotherapeutics are approved and available to patients (Table 32.1). In addition, 324 medically related, biotechnology-derived medicines for nearly 150 diseases are in clinical trials or under review by the U.S. Food and Drug Administration.2 These biopharmaceutical candidates promise to bring more and better treatments to patients. Compared to small molecule drugs, biotherapeutics show exquisite specificity with fewer off-target interactions and improved safety profiles.

  10. Surface Inspection Machine Infrared (SIMIR). Final CRADA report

    Energy Technology Data Exchange (ETDEWEB)

    Powell, G.L. [Lockheed Martin Energy Systems, Inc., Oak Ridge, TN (United States); Neu, J.T.; Beecroft, M. [Surface Optics Corp., San Diego, CA (United States)

    1997-02-28

    This Cooperative Research and Development Agreement was a one year effort to make the surface inspection machine based on diffuse reflectance infrared spectroscopy (Surface Inspection Machine-Infrared, SIMIR), being developed by Surface Optics Corporation, perform to its highest potential as a practical, portable surface inspection machine. The design function of the SIMIR is to inspect metal surfaces for cleanliness (stains). The system is also capable of evaluating graphite-resin systems for cure and heat damage, and for measuring the effects of moisture exposure on lithium hydride, corrosion on uranium metal, and the constituents of and contamination on wood, paper, and fabrics. Over the period of the CRADA, extensive experience with the use of the SIMIR for surface cleanliness measurements have been achieved through collaborations with NASA and the Army. The SIMIR was made available to the AMTEX CRADA for Finish on Yarn where it made a very significant contribution. The SIMIR was the foundation of a Forest Products CRADA that was developed over the time interval of this CRADA. Surface Optics Corporation and the SIMIR have been introduced to the chemical spectroscopy on-line analysis market and have made staffing additions and arrangements for international marketing of the SIMIR as an on-line surface inspection device. LMES has been introduced to a wide range of aerospace applications, the research and fabrication skills of Surface Optics Corporation, has gained extensive experience in the areas of surface cleanliness from collaborations with NASA and the Army, and an extensive introduction to the textile and forest products industries. The SIMIR, marketed as the SOC-400, has filled an important new technology need in the DOE-DP Enhanced Surveillance Program with instruments delivered to or on order by LMES, LANL, LLNL, and Pantex, where extensive collaborations are underway to implement and improve this technology.

  11. Surface Inspection Machine Infrared (SIMIR). Final CRADA report

    International Nuclear Information System (INIS)

    Powell, G.L.; Neu, J.T.; Beecroft, M.

    1997-01-01

    This Cooperative Research and Development Agreement was a one year effort to make the surface inspection machine based on diffuse reflectance infrared spectroscopy (Surface Inspection Machine-Infrared, SIMIR), being developed by Surface Optics Corporation, perform to its highest potential as a practical, portable surface inspection machine. The design function of the SIMIR is to inspect metal surfaces for cleanliness (stains). The system is also capable of evaluating graphite-resin systems for cure and heat damage, and for measuring the effects of moisture exposure on lithium hydride, corrosion on uranium metal, and the constituents of and contamination on wood, paper, and fabrics. Over the period of the CRADA, extensive experience with the use of the SIMIR for surface cleanliness measurements have been achieved through collaborations with NASA and the Army. The SIMIR was made available to the AMTEX CRADA for Finish on Yarn where it made a very significant contribution. The SIMIR was the foundation of a Forest Products CRADA that was developed over the time interval of this CRADA. Surface Optics Corporation and the SIMIR have been introduced to the chemical spectroscopy on-line analysis market and have made staffing additions and arrangements for international marketing of the SIMIR as an on-line surface inspection device. LMES has been introduced to a wide range of aerospace applications, the research and fabrication skills of Surface Optics Corporation, has gained extensive experience in the areas of surface cleanliness from collaborations with NASA and the Army, and an extensive introduction to the textile and forest products industries. The SIMIR, marketed as the SOC-400, has filled an important new technology need in the DOE-DP Enhanced Surveillance Program with instruments delivered to or on order by LMES, LANL, LLNL, and Pantex, where extensive collaborations are underway to implement and improve this technology

  12. 40 CFR 1042.320 - What happens if one of my production-line engines fails to meet emission standards?

    Science.gov (United States)

    2010-07-01

    ... an initial failed test if all of the following are true: (1) The catalyst was in a green condition... 40 Protection of Environment 32 2010-07-01 2010-07-01 false What happens if one of my production... MARINE COMPRESSION-IGNITION ENGINES AND VESSELS Testing Production-line Engines § 1042.320 What happens...

  13. Evaluation of the influence of dominance rules for the assembly line design problem under consideration of product design alternatives

    Science.gov (United States)

    Oesterle, Jonathan; Lionel, Amodeo

    2018-06-01

    The current competitive situation increases the importance of realistically estimating product costs during the early phases of product and assembly line planning projects. In this article, several multi-objective algorithms using difference dominance rules are proposed to solve the problem associated with the selection of the most effective combination of product and assembly lines. The list of developed algorithms includes variants of ant colony algorithms, evolutionary algorithms and imperialist competitive algorithms. The performance of each algorithm and dominance rule is analysed by five multi-objective quality indicators and fifty problem instances. The algorithms and dominance rules are ranked using a non-parametric statistical test.

  14. Sustainable production of azadirachtin from differentiated in vitro cell lines of neem (Azadirachta indica)

    Science.gov (United States)

    Singh, Mithilesh; Chaturvedi, Rakhi

    2013-01-01

    Azadirachtin has high industrial demand due to its immediate application as an ecofriendly, biodegradable biopesticide and also due to its various other significant bioactivities. To date, the only commercially feasible way to produce azadirachtin is extraction from seeds, but their availability is very limited as the tree flowers only once a year and only one-third of the fruits are collected due to operational problems. Further, due to the strict out-breeding nature of the plant, the seeds are highly heterozygous, resulting in inconsistent metabolite production. Therefore, in the present study, to achieve sustainable production of azadirachtin, dedifferentiated and redifferentiated calli derived from various explants of neem—zygotic embryo, leaf and ovary—were investigated for their potential to biosynthesize azadirachtin. High-performance liquid chromatography analysis of the in vitro cell lines showed the presence of azadirachtin in all the samples tested, the content of which in cultured cells varied with explant source and cell differentiation response. The presence of azadirachtin in samples was further confirmed by positive electrospray ionization mass spectroscopy. The zygotic embryo cultures of neem accumulated much higher amounts of azadirachtin than leaf and ovary cultures. Furthermore, organized in vitro callus cultures (redifferentiated) supported higher azadirachtin biosynthesis, while unorganized callus cultures (dedifferentiated) supported the least. The maximum azadirachtin content of 2.33 mg g−1 dry weight was obtained from redifferentiated immature zygotic embryo cultures.

  15. Decreased immunoglobulin production by a human lymphoid cell line following melphalan treatment

    Energy Technology Data Exchange (ETDEWEB)

    Griffin, G.D. (Oak Ridge National Lab., TN); Owen, B.A.; Atchley, C.E.; Novelli, G.D.; Solomon, A.

    1982-11-01

    The effect of melphalan on immunoglobulin G (IgG) production by a human lymphoblastoid cell line (BF) was studied. The amount of secreted IgG and the percentage of cells containing cytoplasmic IgG were measured by immunoassay and cytofluorometry, respectively. Dose-response studies indicated that melphalan concentrations of 2 x 10/sup -8/ M had no effect, while concentrations of 8 x 10/sup -7/ M were totally toxic, after 72-h exposures to the drug. Statistically significant, persistent, alterations in both synthesis and secretion of IgG by BF cells were observed following treatment for 72 h with 4 x 10/sup -7/ M melphalan, and there was an increase in population-doubling time from 24 to 72 h in these drug-treated cells. The percentage of IgG-containing cells in melphalan-treated cultures was significantly decreased as compared to control cultures. IgG secretion was also decreased in these cultures, and the variation in IgG secretion as a function of cellular growth was significantly altered following melphalan treatment. Decreased IgG production following melphalan treatment may be related to altered cell cycle kinetics. Based on immunological analysis, there was no evident alteration in the IgG secreted by melphalan-treated cells, nor did melphalan treatment produce a cellular population lacking IgG entirely.

  16. Genetic line comparisons and genetic parameters for endoparasite infections and test-day milk production traits.

    Science.gov (United States)

    May, Katharina; Brügemann, Kerstin; Yin, Tong; Scheper, Carsten; Strube, Christina; König, Sven

    2017-09-01

    Keeping dairy cows in grassland systems relies on detailed analyses of genetic resistance against endoparasite infections, including between- and within-breed genetic evaluations. The objectives of this study were (1) to compare different Black and White dairy cattle selection lines for endoparasite infections and (2) the estimation of genetic (co)variance components for endoparasite and test-day milk production traits within the Black and White cattle population. A total of 2,006 fecal samples were taken during 2 farm visits in summer and autumn 2015 from 1,166 cows kept in 17 small- and medium-scale organic and conventional German grassland farms. Fecal egg counts were determined for gastrointestinal nematodes (FEC-GIN) and flukes (FEC-FLU), and fecal larvae counts for the bovine lungworm Dictyocaulus viviparus (FLC-DV). The lowest values for gastrointestinal nematode infections were identified for genetic lines adopted to pasture-based production systems, especially selection lines from New Zealand. Heritabilities were low for FEC-GIN (0.05-0.06 ± 0.04) and FLC-DV (0.05 ± 0.04), but moderate for FEC-FLU (0.33 ± 0.06). Almost identical heritabilities were estimated for different endoparasite trait transformations (log-transformation, square root). The genetic correlation between FEC-GIN and FLC-DV was 1.00 ± 0.60, slightly negative between FEC-GIN and FEC-FLU (-0.10 ± 0.27), and close to zero between FLC-DV and FEC-FLU (0.03 ± 0.30). Random regression test-day models on a continuous time scale [days in milk (DIM)] were applied to estimate genetic relationships between endoparasite and longitudinal test-day production traits. Genetic correlations were negative between FEC-GIN and milk yield (MY) until DIM 85, and between FEC-FLU and MY until DIM 215. Genetic correlations between FLC-DV and MY were negative throughout lactation, indicating improved disease resistance for high-productivity cows. Genetic relationships between FEC-GIN and FEC-FLU with milk

  17. Productivity, adaptability and stability of high-oleic peanut lines in the State of São Paulo

    Directory of Open Access Journals (Sweden)

    João Francisco dos Santos

    2018-04-01

    Full Text Available ABSTRACT Estimating stability and adaptability parameters of cultivars is a widely used study to access the genotype × environment interaction, in order to identify the best genotypes for each cultivation area. In this study, the adaptability and stability parameters were estimated in eight high-oleic lines and two peanut cultivars in 11 experiments in the State of São Paulo, Brazil, from 2008 to 2013, based on the data of the plots mean productivity (Kg·ha–1, with the objective of recommending the most productive genotypes in peanut producing regions in the State of São Paulo. The design used for these experiments was the randomized complete blocks, with four replications. Lines L. 599 and L. 551 were the best genotypes regarding overall adaptability and stability in yield, considering the methods of Eberhart and Russell and of Lin and Binns modified by Carneiro. Results produced by both methods were convergent as for the classification of the lines, and the use of one of them would not be detrimental to the recommendation of productive lines associated to production adaptability and stability. The overall adaptability in addition to the stability in the productivity of the lines here evaluated showed outstanding performance in relation to the cultivars IAC Caiapó and Runner IAC 886.

  18. On automatic visual inspection of reflective surfaces

    DEFF Research Database (Denmark)

    Kulmann, Lionel

    1995-01-01

    surfaces, providing new and exciting applications subject to automated visual inspection. Several contextual features have been surveyed along with introduction of novel methods to perform data-dependent enhancement of local surface appearance . Morphological methods have been described and utilized......This thesis descrbes different methods to perform automatic visual inspection of reflective manufactured products, with the aim of increasing productivity, reduce cost and improve the quality level of the production. We investigate two different systems performing automatic visual inspection....... The first is the inspection of highly reflective aluminum sheets, used by the Danish company Bang & Olufsen, as a part of the exterior design and general appearance of their audio and video products. The second is the inspection of IBM hard disk read/write heads for defects during manufacturing. We have...

  19. Tuberculosis drug issues: prices, fixed-dose combination products and second-line drugs.

    Science.gov (United States)

    Laing, R O; McGoldrick, K M

    2000-12-01

    Access to tuberculosis drugs depends on multiple factors. Selection of a standard list of TB drugs to procure is the first step. This paper reviews the advantages and disadvantages of procuring and using fixed-dose combination (FDC) products for both the intensive and continuation phases of treatment. The major advantages are to prevent the emergence of resistance, to simplify logistic management and to reduce costs. The major disadvantage is the need for the manufacturers to assure the quality of these FDCs by bioavailability testing. The paper reports on the inclusion of second-line TB drugs in the 1999 WHO Essential Drug List (EDL). The need to ensure that these drugs are used within established DOTS-Plus programs is stressed. The price of TB drugs is determined by many factors, including producer prices, local taxes and duties as well as mark-ups and fees. TB drug prices for both the public and private sectors from industrialized and developing countries are reported. Price trends over time are also reported. The key findings of this study are that TB drug prices have generally declined in developing countries while they have increased in developed countries, both for the public and private sectors. Prices vary between countries, with the US paying as much as 95 times the price paid in a specific developing country. The prices of public sector first-line TB drugs vary little between countries, although differences do exist due to the procurement methods used. The price of tuberculin, a diagnostic agent, has increased dramatically in the US, with substantial inter-country variations in price. The paper suggests that further research is necessary to identify the reasons for the price disparities and changes over time, and suggests methods which can be used by National Tuberculosis Programme managers to ensure availability of quality assured TB drugs at low prices.

  20. After-production and in-service inspections of components of nuclear power plant primary coolant circuits

    International Nuclear Information System (INIS)

    Slama, K.; Svetlik, M.

    1990-01-01

    A new diagnostic system was developed for detecting defects in the material of mechanically loaded equipment. It is based on the measurement of elastic strain waves propagating through the materials. The instrument units as well as the methodology and software are of Czechoslovak origin and can be modified to conform to the requirements and experience of the user. The way of applying the method to the diagnostics of pressure vessels, main circulation pumps of the pressurizers and of the primary piping is described. Some results of after-production and in-service acoustic emission tests are given, as are the technical parameters of the acoustic emission analyzer. (M.D.). 5 figs

  1. 9 CFR 2.128 - Inspection for missing animals.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Inspection for missing animals. 2.128 Section 2.128 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Miscellaneous § 2.128 Inspection for missing animals. Each dealer...

  2. 9 CFR 590.660 - Inspection of exempted plants.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Inspection of exempted plants. 590.660... Products Plants § 590.660 Inspection of exempted plants. Duly authorized representatives of the Administrator shall make such periodic inspections of exempted plants and records thereof as the Administrator...

  3. 7 CFR 205.403 - On-site inspections.

    Science.gov (United States)

    2010-01-01

    ..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) ORGANIC FOODS PRODUCTION ACT PROVISIONS NATIONAL ORGANIC PROGRAM Certification § 205.403 On-site inspections. (a) On-site inspections. (1... site that produces or handles organic products and that is included in an operation for which...

  4. 9 CFR 381.14 - Inspection concerning purportedly exempted operations.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Inspection concerning purportedly exempted operations. 381.14 Section 381.14 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE... make inspections in accordance with law to ascertain whether any of the provisions of the Act or the...

  5. Wafer plane inspection for advanced reticle defects

    Science.gov (United States)

    Nagpal, Rajesh; Ghadiali, Firoz; Kim, Jun; Huang, Tracy; Pang, Song

    2008-05-01

    Readiness of new mask defect inspection technology is one of the key enablers for insertion & transition of the next generation technology from development into production. High volume production in mask shops and wafer fabs demands a reticle inspection system with superior sensitivity complemented by a low false defect rate to ensure fast turnaround of reticle repair and defect disposition (W. Chou et al 2007). Wafer Plane Inspection (WPI) is a novel approach to mask defect inspection, complementing the high resolution inspection capabilities of the TeraScanHR defect inspection system. WPI is accomplished by using the high resolution mask images to construct a physical mask model (D. Pettibone et al 1999). This mask model is then used to create the mask image in the wafer aerial plane. A threshold model is applied to enhance the inspectability of printing defects. WPI can eliminate the mask restrictions imposed on OPC solutions by inspection tool limitations in the past. Historically, minimum image restrictions were required to avoid nuisance inspection stops and/or subsequent loss of sensitivity to defects. WPI has the potential to eliminate these limitations by moving the mask defect inspections to the wafer plane. This paper outlines Wafer Plane Inspection technology, and explores the application of this technology to advanced reticle inspection. A total of twelve representative critical layers were inspected using WPI die-to-die mode. The results from scanning these advanced reticles have shown that applying WPI with a pixel size of 90nm (WPI P90) captures all the defects of interest (DOI) with low false defect detection rates. In validating CD predictions, the delta CDs from WPI are compared against Aerial Imaging Measurement System (AIMS), where a good correlation is established between WPI and AIMSTM.

  6. The use of statistical procedures for comparison of the production of eggs considering different treatments and lines of quails

    Directory of Open Access Journals (Sweden)

    Robson Marcelo Rossi

    2012-04-01

    Full Text Available To make inferences concerning a population, parametric methods are traditionally used for sample data analysis assuming that these come from ordinary populations, which not always happens. Most of the times such assumption leads to inadequate conclusions and decisions, especially when the data are distributed asymmetrically. It was aimed on this work to adjust some plausible models for this type of data, aiming to compare eggs productions in quails of different lines through frequentist and Bayesian methods. In the analyzed data it could be verified that the parametric and non-parametric frequentist procedures were, in general, equally conclusive. The Bayesian procedure was the only one which detected difference between the yellow and red lines, regarding the preconized energy diet, and between the blue and yellow for the second eclosion group. By the frequentist methods differences between the blue and red lines were not found; however, given a Poisson distribution for the eggs production, through multiple comparisons between the posterior mean under the Bayesian focus, differences were found between all lines. For being more sensitive, besides flexible, such procedure detected differences not observed by the traditional methods between the yellow and red lines, in the higher energy diet; between the blue and the red one in the second eclosion group and in general. It was concluded that quails of the yellow line showed bigger eggs production, regardless of the eclosion group and diet. Such results raise the discussion on the appropriate use of methods and procedures for statistical data analysis.

  7. Periodic and in-service inspection programs

    International Nuclear Information System (INIS)

    Dinu, M.

    2000-01-01

    Periodic and in-service inspection programs for Cernavoda NPP consists of periodic inspections of CANDU NPP components CSAN N-285.4 and CSAN N-285.4, in-service inspections and repair and modifications general inspection. Periodic inspection program document (PIPD) determines the systems and components subject to inspection, the category of the inspection, techniques, areas and other details.The current status of the inspection programs is presented, including containment , erosion/corrosion, pressure vessel support and snubbers, main steam lines inspection programs. Qualification program in Cernavoda NPP involves equipment qualification in the on-site laboratory, yearly certification, special equipment qualification in the National Institute of Metrology. All procedures are approved by the ISCIR (regulatory body for pressure vessel and lifting equipment) and CNCAN (National Commission on Nuclear Activities Control). Qualification of the personnel is performed according to the ISCIR Technical prescription CR 11/82 for up to 3 year period. Final qualification and licensing is performed by CNCAN

  8. Development of an automatic reactor inspection system

    International Nuclear Information System (INIS)

    Kim, Jae Hee; Eom, Heung Seop; Lee, Jae Cheol; Choi, Yoo Raek; Moon, Soon Seung

    2002-02-01

    Using recent technologies on a mobile robot computer science, we developed an automatic inspection system for weld lines of the reactor vessel. The ultrasonic inspection of the reactor pressure vessel is currently performed by commercialized robot manipulators. Since, however, the conventional fixed type robot manipulator is very huge, heavy and expensive, it needs long inspection time and is hard to handle and maintain. In order to resolve these problems, we developed a new automatic inspection system using a small mobile robot crawling on the vertical wall of the reactor vessel. According to our conceptual design, we developed the reactor inspection system including an underwater inspection robot, a laser position control subsystem, an ultrasonic data acquisition/analysis subsystem and a main control subsystem. We successfully carried out underwater experiments on the reactor vessel mockup, and real reactor ready for Ulchine nuclear power plant unit 6 at Dusan Heavy Industry in Korea. After this project, we have a plan to commercialize our inspection system. Using this system, we can expect much reduction of the inspection time, performance enhancement, automatic management of inspection history, etc. In the economic point of view, we can also expect import substitution more than 4 million dollars. The established essential technologies for intelligent control and automation are expected to be synthetically applied to the automation of similar systems in nuclear power plants

  9. 7 CFR 51.39 - Fees for appeal inspections.

    Science.gov (United States)

    2010-01-01

    ... Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 FRESH FRUITS, VEGETABLES AND OTHER PRODUCTS 1,2 (INSPECTION, CERTIFICATION, AND...

  10. Results from a new 193nm die-to-database reticle inspection platform

    Science.gov (United States)

    Broadbent, William H.; Alles, David S.; Giusti, Michael T.; Kvamme, Damon F.; Shi, Rui-fang; Sousa, Weston L.; Walsh, Robert; Xiong, Yalin

    2010-05-01

    A new 193nm wavelength high resolution reticle defect inspection platform has been developed for both die-to-database and die-to-die inspection modes. In its initial configuration, this innovative platform has been designed to meet the reticle qualification requirements of the IC industry for the 22nm logic and 3xhp memory generations (and shrinks) with planned extensions to the next generation. The 22nm/3xhp IC generation includes advanced 193nm optical lithography using conventional RET, advanced computational lithography, and double patterning. Further, EUV pilot line lithography is beginning. This advanced 193nm inspection platform has world-class performance and the capability to meet these diverse needs in optical and EUV lithography. The architecture of the new 193nm inspection platform is described. Die-to-database inspection results are shown on a variety of reticles from industry sources; these reticles include standard programmed defect test reticles, as well as advanced optical and EUV product and product-like reticles. Results show high sensitivity and low false and nuisance detections on complex optical reticle designs and small feature size EUV reticles. A direct comparison with the existing industry standard 257nm wavelength inspection system shows measurable sensitivity improvement for small feature sizes

  11. Automated reticle inspection data analysis for wafer fabs

    Science.gov (United States)

    Summers, Derek; Chen, Gong; Reese, Bryan; Hutchinson, Trent; Liesching, Marcus; Ying, Hai; Dover, Russell

    2009-04-01

    To minimize potential wafer yield loss due to mask defects, most wafer fabs implement some form of reticle inspection system to monitor photomask quality in high-volume wafer manufacturing environments. Traditionally, experienced operators review reticle defects found by an inspection tool and then manually classify each defect as 'pass, warn, or fail' based on its size and location. However, in the event reticle defects are suspected of causing repeating wafer defects on a completed wafer, potential defects on all associated reticles must be manually searched on a layer-by-layer basis in an effort to identify the reticle responsible for the wafer yield loss. This 'problem reticle' search process is a very tedious and time-consuming task and may cause extended manufacturing line-down situations. Often times, Process Engineers and other team members need to manually investigate several reticle inspection reports to determine if yield loss can be tied to a specific layer. Because of the very nature of this detailed work, calculation errors may occur resulting in an incorrect root cause analysis effort. These delays waste valuable resources that could be spent working on other more productive activities. This paper examines an automated software solution for converting KLA-Tencor reticle inspection defect maps into a format compatible with KLA-Tencor's Klarity Defect(R) data analysis database. The objective is to use the graphical charting capabilities of Klarity Defect to reveal a clearer understanding of defect trends for individual reticle layers or entire mask sets. Automated analysis features include reticle defect count trend analysis and potentially stacking reticle defect maps for signature analysis against wafer inspection defect data. Other possible benefits include optimizing reticle inspection sample plans in an effort to support "lean manufacturing" initiatives for wafer fabs.

  12. Interferon production and signaling pathways are antagonized during henipavirus infection of fruit bat cell lines.

    Directory of Open Access Journals (Sweden)

    Elena R Virtue

    Full Text Available Bats are natural reservoirs for a spectrum of infectious zoonotic diseases including the recently emerged henipaviruses (Hendra and Nipah viruses. Henipaviruses have been observed both naturally and experimentally to cause serious and often fatal disease in many different mammal species, including humans. Interestingly, infection of the flying fox with henipaviruses occurs in the absence of clinical disease. The extreme variation in the disease pattern between humans and bats has led to an investigation into the effects of henipavirus infection on the innate immune response in bat cell lines. We report that henipavirus infection does not result in the induction of interferon expression, and the viruses also inhibit interferon signaling. We also confirm that the interferon production and signaling block in bat cells is not due to differing viral protein expression levels between human and bat hosts. This information, in addition to the known lack of clinical signs in bats following henipavirus infection, suggests that bats control henipavirus infection by an as yet unidentified mechanism, not via the interferon response. This is the first report of henipavirus infection in bat cells specifically investigating aspects of the innate immune system.

  13. A Software Product Line Process to Develop Agents for the IoT.

    Science.gov (United States)

    Ayala, Inmaculada; Amor, Mercedes; Fuentes, Lidia; Troya, José M

    2015-07-01

    One of the most important challenges of this decade is the Internet of Things (IoT), which aims to enable things to be connected anytime, anyplace, with anything and anyone, ideally using any path/network and any service. IoT systems are usually composed of heterogeneous and interconnected lightweight devices that support applications that are subject to change in their external environment and in the functioning of these devices. The management of the variability of these changes, autonomously, is a challenge in the development of these systems. Agents are a good option for developing self-managed IoT systems due to their distributed nature, context-awareness and self-adaptation. Our goal is to enhance the development of IoT applications using agents and software product lines (SPL). Specifically, we propose to use Self-StarMASMAS, multi-agent system) agents and to define an SPL process using the Common Variability Language. In this contribution, we propose an SPL process for Self-StarMAS, paying particular attention to agents embedded in sensor motes.

  14. A Software Product Line Process to Develop Agents for the IoT

    Directory of Open Access Journals (Sweden)

    Inmaculada Ayala

    2015-07-01

    Full Text Available One of the most important challenges of this decade is the Internet of Things (IoT, which aims to enable things to be connected anytime, anyplace, with anything and anyone, ideally using any path/network and any service. IoT systems are usually composed of heterogeneous and interconnected lightweight devices that support applications that are subject to change in their external environment and in the functioning of these devices. The management of the variability of these changes, autonomously, is a challenge in the development of these systems. Agents are a good option for developing self-managed IoT systems due to their distributed nature, context-awareness and self-adaptation. Our goal is to enhance the development of IoT applications using agents and software product lines (SPL. Specifically, we propose to use Self-StarMASMAS, multi-agent system agents and to define an SPL process using the Common Variability Language. In this contribution, we propose an SPL process for Self-StarMAS, paying particular attention to agents embedded in sensor motes.

  15. Production of chemically reactive radioactive ion beams through on-line separation

    International Nuclear Information System (INIS)

    Joinet, A.

    2003-10-01

    The ISOL (isotope separation on line) allows the production of secondary radioactive ion beams through spallation or fragmentation or fission reactions that take place in a thick target bombarded by a high intensity primary beam. The challenge is to increase the intensity and purity of the radioactive beam. The optimization of the system target/source requires the right choice of material for the target by taking into account the stability of the material, its reactivity and the ionization method used. The target is an essential part of the system because radioactive elements are generated in it and are released more or less quickly. Tests have been made in order to select the best fitted material for the release of S, Se, Te, Ge and Sn. Materials tested as target filling are: ZrO 2 , Nb, Ti, V,TiO 2 , CeO x , ThO 2 , C, ZrC 4 and VC). Other molecules such as: COSe, COS, SeS, COTe, GeS, SiS, SnS have been studied to ease the extraction of recoil nuclei (Se, S, Te, Ge and Sn) produced inside the target

  16. General requirements applicable to the production, inspection, processing, packaging and storage of various types of waste resulting from the reprocessing of fuels irradiated in pressurized light water reactors

    International Nuclear Information System (INIS)

    1982-09-01

    The Fundamental Safety Rules applicable to certain types of nuclear installation are intended to clarify the conditions of which observance, for the type of installation concerned and for the subject that they deal with, is considered as equivalent to compliance with regulatory French technical practice. These Rules should facilitate safety analysises and the clear understanding between persons interested in matters related to nuclear safety. They in no way reduce the operator's liability and pose no obstacle to statutory provisions in force. For any installation to which a Fundamental Safety Rule applies according to the foregoing paragraph, the operator may be relieved from application of the Rule if he shows proof that the safety objectives set by the Rule are attained by other means that he proposes within the framework of statutory procedures. Furthermore, the Central Service for the Safety of Nuclear Installations reserves the right at all times to alter any Fundamental Safety Rule, as required, should it deem this necessary, while specifying the applicability conditions. This rule is intended to define the general provisions applicable to the production, inspection, processing, packaging and storage of the different types of wastes resulting from the reprocessing of fuels irradiated in a PWR

  17. Computerized information system for inventory-taking and verification at a nuclear fuel fabrication plant with closed production lines

    International Nuclear Information System (INIS)

    Bahm, W.; Brueckner, C.; Hartmann, G.

    1976-01-01

    By means of a model the use of electronic data processing is studied for preparing inventory listings and for inventory verification in a fabrication plant for Pu-U mixed-oxide fuel pins. It is postulated that interruptions in operation should be avoided as much as possible. Closed-Line production is assumed so that access to nuclear material calls for special withdrawal via locks. The production line is subdivided into sections with measuring points placed in between to record the nuclear material flow. The measured results are fed to a central data acquisition and reporting system capable of calculating on-line from these results the book inventories present in the individual sections. Inventory-taking and verification are carried out simultaneously in the sections of the production line using the EDP system. The production is not interrupted for this purpose. The production stream is tagged prior to reaching a section to be measured and is subsequently measured when entering the respective section until the tag has reached the end of the section. The measurement can be verified by inspectors. Movements of nuclear materials in and from other plant areas such as the storage area are likewise fed into the central data processing system so that inventory lists can be recalled at any moment. By this means the inventory can be taken quickly and at any time. The inventory is verified in the conventional way. (author)

  18. Production of coagulation factor VII in human cell lines Sk-Hep-1 and HKB-11.

    Science.gov (United States)

    Corrêa de Freitas, Marcela Cristina; Bomfim, Aline de Sousa; Mizukami, Amanda; Picanço-Castro, Virgínia; Swiech, Kamilla; Covas, Dimas Tadeu

    2017-09-01

    Recombinant factor VII (rFVII) is the main therapeutic choice for hemophilia patients who have developed inhibitory antibodies against conventional treatments (FVIII and FIX). Because of the post-translational modifications, rFVII needs to be produced in mammalian cell lines. In this study, for the first time, we have shown efficient rFVII production in HepG2, Sk-Hep-1, and HKB-11 cell lines. Experiments in static conditions for a period of 96 h showed that HepG2-FVII produced the highest amounts of rhFVII, with an average of 1843 ng/mL. Sk-hep-1-FVII cells reached a maximum protein production of 1432 ng/mL and HKB-11-FVII cells reached 1468 ng/mL. Sk-Hep-1-rFVII and HKB-11-rFVII were selected for the first step of scale-up. Over 10 days of spinner flask culture, HKB-11 and SK-Hep-1 cells showed a cumulative production of rFVII of 152 μg and 202.6 μg in 50 mL, respectively. Thus, these human cell lines can be used for an efficient production of recombinant FVII. With more investment in basic research, human cell lines can be optimized for the commercial production of different bio therapeutic proteins. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. 14 CFR 21.615 - FAA inspection.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false FAA inspection. 21.615 Section 21.615 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT CERTIFICATION PROCEDURES FOR PRODUCTS AND PARTS Technical Standard Order Authorizations § 21.615 FAA inspection. Upon the...

  20. Design and implementation for integrated UAV multi-spectral inspection system

    Science.gov (United States)

    Zhu, X.; Li, X.; Yan, F.

    2018-04-01

    In order to improve the working efficiency of the transmission line inspection and reduce the labour intensity of the inspectors, this paper presents an Unmanned Aerial Vehicle (UAV) inspection system architecture for the transmission line inspection. In this document, the light-duty design for different inspection equipment and processing terminals is completed. It presents the reference design for the information-processing terminal, supporting the inspection and interactive equipment accessing, and obtains all performance indicators of the inspection information processing through the tests. Practical application shows that the UAV inspection system supports access and management of different types of mainstream fault detection equipment, and can implement the independent diagnosis of the detected information to generate inspection reports in line with industry norms, which can meet the fast, timely, and efficient requirements for the power line inspection work.

  1. Cytokines Expression and Nitric Oxide Production under Induced Infection to Typhimurium in Chicken Lines Divergently Selected for Cutaneous Hypersensitivity

    Directory of Open Access Journals (Sweden)

    Rani Singh

    2012-07-01

    Full Text Available In the present study, the impact of Salmonella Typhimurium on cell-mediated immunity (CMI was investigated in 5 week-old immuno divergent broiler lines selected for the high and low response to phytohemagglutinin-P. The immune response was assessed in peripheral-blood mononuclear cells (PBMCs induced with Salmonella Typhimurium at different time intervals (0 h, 0.5 h, 2 h, 4 h, 6 h, 12 h and 24 h. The differential mRNA expression patterns of IFN-γ, IL-2 and iNOS were evaluated by quantitative real time PCR. In-vitro production of nitric oxide (NO was also estimated in the culture supernatant and correlated with iNOS mRNA expression. Present study showed higher production of NO in the high cell-mediated line (HCMI as compared to the low cell-mediated line (LCMI upon stimulation with Salmonella Typhimurium. Correspondingly, higher mRNA expression of iNOS and IFN-γ were observed in high response birds (HCMI; but IL-2 was down regulated in this line compared to the low response birds (LCMI. Significantly (p<0.05 higher expression of iNOS, IFN-γ and higher production of NO in high line indicated that the selection for PHA-P response might be employed for increasing the immune competence against Salmonella Typhimurium in chicken flocks.

  2. A multi-purpose tool for food inspection: Simultaneous determination of various classes of preservatives and biogenic amines in meat and fish products by LC-MS.

    Science.gov (United States)

    Molognoni, Luciano; Daguer, Heitor; de Sá Ploêncio, Leandro Antunes; De Dea Lindner, Juliano

    2018-02-01

    This paper describes an innovative fast and multipurpose method for the chemical inspection of meat and fish products by liquid chromatography-tandem mass spectrometry. Solid-liquid extraction and low temperature partitioning were applied to 17 analytes, which included large bacteriocins (3.5kDa) and small molecules (organic acids, heterocyclic compounds, polyene macrolides, alkyl esters of the p-hydroxybenzoic acid, aromatic, and aliphatic biogenic amines and polyamines). Chromatographic separation was achieved in 10min, using stationary phase of di-isopropyl-3-aminopropyl silane bound to hydroxylated silica. Method validation was in accordance to Commission Decision 657/2002/CE. Linear ranges were among 1.25-10.0mgkg -1 (natamycin and parabens), 2.50-10.0mgkg -1 (sorbate and nisin), 25.0-200mgkg -1 (biogenic amines, hexamethylenetetramine, benzoic and lactic acids), and 50.0-400mgkg -1 (citric acid). Expanded measurement uncertainty (U) was estimated by single laboratory validation combined to modeling in two calculation approaches: internal (U = 5%) and external standardization (U = 24%). Method applicability was checked on 89 real samples among raw, cooked, dry fermented and cured products, yielding acceptable recoveries. Many regulatory issues were revealed, corroborating the need for enhancement of the current analytical methods. This simple execution method dispenses the use of additional procedures of extraction and, therefore, reduces costs over time. It is suitable for routine analysis as a screening or confirmatory tool for both qualitative and quantitative results, replacing many time consuming analytical procedures. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. ROBOTIC TANK INSPECTION END EFFECTOR

    International Nuclear Information System (INIS)

    Rachel Landry

    1999-01-01

    The objective of this contract between Oceaneering Space Systems (OSS) and the Department of Energy (DOE) was to provide a tool for the DOE to inspect the inside tank walls of underground radioactive waste storage tanks in their tank farms. Some of these tanks are suspected to have leaks, but the harsh nature of the environment within the tanks precludes human inspection of tank walls. As a result of these conditions only a few inspection methods can fulfill this task. Of the methods available, OSS chose to pursue Alternating Current Field Measurement (ACFM), because it does not require clean surfaces for inspection, nor any contact with the Surface being inspected, and introduces no extra by-products in the inspection process (no coupling fluids or residues are left behind). The tool produced by OSS is the Robotic Tank Inspection End Effector (RTIEE), which is initially deployed on the tip of the Light Duty Utility Arm (LDUA). The RTEE combines ACFM with a color video camera for both electromagnetic and visual inspection The complete package consists of an end effector, its corresponding electronics and software, and a user's manual to guide the operator through an inspection. The system has both coarse and fine inspection modes and allows the user to catalog defects and suspected areas of leakage in a database for further examination, which may lead to emptying the tank for repair, decommissioning, etc.. The following is an updated report to OSS document OSS-21100-7002, which was submitted in 1995. During the course of the contract, two related sub-tasks arose, the Wall and Coating Thickness Sensor and the Vacuum Scarifying and Sampling Tool Assembly. The first of these sub-tasks was intended to evaluate the corrosion and wall thinning of 55-gallon steel drums. The second was retrieved and characterized the waste material trapped inside the annulus region of the underground tanks on the DOE's tank farms. While these sub-tasks were derived from the original intent

  4. Environmental and life cycle analysis of a biodiesel production line from sunflower in the Province of Siena (Italy)

    International Nuclear Information System (INIS)

    Spinelli, D.; Jez, S.; Pogni, R.; Basosi, R.

    2013-01-01

    The Directive 2009/28/EC established the overall target that 20% of energy consumption should be represented by renewable energy sources by 2020 in each European member state. Furthermore, the Directive sets a mandatory 10% minimum target for biofuels in the transport sector. Biofuels are potentially an important alternative to mineral diesel. We propose a pilot production line of biodiesel from sunflower on local scale in the Province of Siena (Tuscany) to research a possible reduction of fossil fuel consumption in the transport sector. This study might represent an opportunity to reduce petroleum dependence in the transport sector. Environmental Impact Indicators were provided by Material Flow Accounting, Embodied Energy Analysis and Emergy Accounting. Results showed that agricultural phase is the critical step in the production line. A comparative Life Cycle Assessment analysis for the biodiesel production line with mineral diesel production showed environmental advantages of the biofuel production, however requiring a higher land demand. Therefore, biodiesel may not the optimal solution on large scale but might be a good alternative to fossil fuel. This would depend upon the entire production cycle taking place in a limited area. This is necessary in order to fulfill the needs of local farms and small enterprises. - Highlights: • Environmental profile of the biodiesel production from sunflower was evaluated. • Agricultural phase is the critical step in the whole production line. • Biodiesel from sunflower cannot be considered a totally renewable energy source. • Biodiesel shows advantages in respect to mineral diesel but a higher land demand. • Biodiesel mix may be a good solution on local scale

  5. 75 FR 63814 - Certain Lined Paper Products From the People's Republic of China: Notice of Preliminary Results...

    Science.gov (United States)

    2010-10-18

    ... consist of hole-punched or drilled filler paper; Three-ring or multiple-ring binders, or notebook organizers incorporating such a ring binder provided that they do not include subject paper; Index cards... DEPARTMENT OF COMMERCE International Trade Administration [A-570-901] Certain Lined Paper Products...

  6. A system for accurate on-line measurement of total gas consumption or production rates in microbioreactors

    NARCIS (Netherlands)

    van Leeuwen, Michiel; Heijnen, Joseph J.; Gardeniers, Johannes G.E.; Oudshoorn, Arthur; Noorman, Henk; Visser, Jan; van der Wielen, Luuk A.M.; van Gulik, Walter M.

    2009-01-01

    A system has been developed, based on pressure controlled gas pumping, for accurate measurement of total gas consumption or production rates in the nmol/min range, applicable for on-line monitoring of bioconversions in microbioreactors. The system was validated by carrying out a bioconversion with

  7. 40 CFR 1051.325 - What happens if an engine family fails the production-line testing requirements?

    Science.gov (United States)

    2010-07-01

    ... ENGINES AND VEHICLES Testing Production-Line Vehicles and Engines § 1051.325 What happens if an engine... for an engine family if it fails under § 1051.315. The suspension may apply to all facilities producing vehicles or engines from an engine family, even if you find noncompliant vehicles or engines only...

  8. A scheme to expand the delay-bandwidth product in the resonator-based delay lines by optical OFDM technique

    DEFF Research Database (Denmark)

    Zhu, Jiangbo; Tao, Li; Zhang, Ziran

    2013-01-01

    We propose a novel scheme to expand the inherent limit in the product of the optical delay and the transmission bandwidth in resonator-based delay lines, with the optical orthogonal frequency division multiplexing (OOFDM) technique. The optical group delay properties of a single ring resonator we...

  9. 银镜生产线操作工艺%Production Operating Technology of Silver-mirror Line

    Institute of Scientific and Technical Information of China (English)

    徐卫民; 杨晨; 梁中生

    2011-01-01

    详细介绍了银镜生产线的实际操作工艺,阐述了每道工序的注意事项。%The practical operating technology of silver-mirror production line was described in details and the matters need attention at every stage were also presented.

  10. Feasibility of evaluating possible sup 85 Kr environmental contamination from neon lamp production line to be installed

    Energy Technology Data Exchange (ETDEWEB)

    Guangzuo, Li [Chengdu Sanitary-Epidemiological Station, Chengdu, SC (China)

    1989-12-01

    Using a simplified method, the concentrations of {sup 85}Kr leaking into the air of a workshop and its surroundings, where a neon lamp production line was to be installed, were calculated. The doses to the workers and inhabitants nearby were also estimated. Thus, the evaluation of {sup 85}Kr enviromental contamination caused by imported equipments was made feasible.

  11. Maximizing the peak production rate in off-line comprehensive two-dimensional liquid chromatography with mass spectrometry detection

    NARCIS (Netherlands)

    Eeltink, S.; Dolman, S.; Ursem, M.; Swart, R.; McLeod, F.; Schoenmakers, P.J.

    2009-01-01

    This article describes an optimization strategy to obtain the best possible performance in the shortest analysis time—called the peak production rate—for comprehensive off-line two-dimensional liquid chromatography. The demands on column technology (particle size and column length) and LC conditions

  12. Automated Inspection of Aircraft

    Science.gov (United States)

    1998-04-01

    This report summarizes the development of a robotic system designed to assist aircraft inspectors by remotely deploying non-destructive inspection (NDI) sensors and acquiring, processing, and storing inspection data. Carnegie Mellon University studie...

  13. Optimising import phytosanitary inspection

    NARCIS (Netherlands)

    Surkov, I.

    2007-01-01

    Keywords: quarantine pest, plant health policy, optimization, import phytosanitary inspection, ‘reduced checks’, optimal allocation of resources, multinomial logistic regression, the Netherlands World trade is a major vector of spread of quarantine plant pests. Border phytosanitary inspection

  14. Experimental and in silico modelling analyses of the gene expression pathway for recombinant antibody and by-product production in NS0 cell lines.

    Science.gov (United States)

    Mead, Emma J; Chiverton, Lesley M; Spurgeon, Sarah K; Martin, Elaine B; Montague, Gary A; Smales, C Mark; von der Haar, Tobias

    2012-01-01

    Monoclonal antibodies are commercially important, high value biotherapeutic drugs used in the treatment of a variety of diseases. These complex molecules consist of two heavy chain and two light chain polypeptides covalently linked by disulphide bonds. They are usually expressed as recombinant proteins from cultured mammalian cells, which are capable of correctly modifying, folding and assembling the polypeptide chains into the native quaternary structure. Such recombinant cell lines often vary in the amounts of product produced and in the heterogeneity of the secreted products. The biological mechanisms of this variation are not fully defined. Here we have utilised experimental and modelling strategies to characterise and define the biology underpinning product heterogeneity in cell lines exhibiting varying antibody expression levels, and then experimentally validated these models. In undertaking these studies we applied and validated biochemical (rate-constant based) and engineering (nonlinear) models of antibody expression to experimental data from four NS0 cell lines with different IgG4 secretion rates. The models predict that export of the full antibody and its fragments are intrinsically linked, and cannot therefore be manipulated individually at the level of the secretory machinery. Instead, the models highlight strategies for the manipulation at the precursor species level to increase recombinant protein yields in both high and low producing cell lines. The models also highlight cell line specific limitations in the antibody expression pathway.

  15. Development and application of an on-line tritium production rate measuring method

    International Nuclear Information System (INIS)

    Yamaguchi, Seiya

    1989-06-01

    A highly sensitive on-line method for measuring the tritium production rate (TPR) of 6 Li was developed using the response difference of 6 Li and 7 Li-glass scintillators in a mixed neutron-gamma radiation field. A fitting method for subtracting the pulse height spectrum of 7 Li-glass from that of 6 Li-glass was introduced. The contribution of competing reactions such as 6 Li (n, n 'd) 4 He was estimated by kinematical analyses. An absolute value of the 6 Li content was determined by a chemical analysis. The thermal flux perturbation due to 6 Li-glass of various thickness and 6 Li contents was evaluated by measurement in a thermal neutron field and calculation by the modified Skyrme theory. A Monte Carlo calculation of the self-shielding effect was also made. The dependence of the self-shielding on neutron energy was examined by this Monte Carlo code. The edge effect, i.e., distortion of the pulse height spectrum due to partial energy deposition of the alpha and/or the triton, was investigated by measurement in a thermal neutron field and by a Monte Carlo simulation that was based on the scintillation mechanism and considered Bragg absorption and the ratio of contributions to luminescence by the alpha and the triton. The dependence of the edge effect on neutron energy was examined by this Monte Carlo code. This method was applied to the measurement of TPR distributions in simulated fusion blanket assemblies bombarded by D-T neutrons. Absolute values of the TPR were obtained with an experimental error of 3∼6 %. The measured results were compared with those of conventional β-counting methods and good agreement was obtained. An optical fiber system, using miniature lithium-glass scintillators, was fabricated for purpose of microminiaturization of detector size and adaption to strong electromagnetic field. Applicability of this system to a D-T neutron field was demonstrated. (author)

  16. Evaluation of the agronomic performance of atrazine-tolerant transgenic japonica rice parental lines for utilization in hybrid seed production.

    Directory of Open Access Journals (Sweden)

    Luhua Zhang

    Full Text Available Currently, the purity of hybrid seed is a crucial limiting factor when developing hybrid japonica rice (Oryza sativa L.. To chemically control hybrid seed purity, we transferred an improved atrazine chlorohydrolase gene (atzA from Pseudomonas ADP into hybrid japonica parental lines (two maintainers, one restorer, and Nipponbare, by using Agrobacterium-mediated transformation. We subsequently selected several transgenic lines from each genotype by using PCR, RT-PCR, and germination analysis. In the presence of the investigated atrazine concentrations, particularly 150 µM atrazine, almost all of the transgenic lines produced significantly larger seedlings, with similar or higher germination percentages, than did the respective controls. Although the seedlings of transgenic lines were taller and gained more root biomass compared to the respective control plants, their growth was nevertheless inhibited by atrazine treatment compared to that without treatment. When grown in soil containing 2 mg/kg or 5 mg/kg atrazine, the transgenic lines were taller, and had higher total chlorophyll contents than did the respective controls; moreover, three of the strongest transgenic lines completely recovered after 45 days of growth. After treatment with 2 mg/kg or 5 mg/kg of atrazine, the atrazine residue remaining in the soil was 2.9-7.0% or 0.8-8.7% respectively, for transgenic lines, and 44.0-59.2% or 28.1-30.8%, respectively, for control plants. Spraying plants at the vegetative growth stage with 0.15% atrazine effectively killed control plants, but not transgenic lines. Our results indicate that transgenic atzA rice plants show tolerance to atrazine, and may be used as parental lines in future hybrid seed production.

  17. Using titer and titer normalized to confluence are complementary strategies for obtaining Chinese hamster ovary cell lines with high volumetric productivity of etanercept

    DEFF Research Database (Denmark)

    Pristovšek, Nuša; Hansen, Henning Gram; Sergeeva, Daria

    2018-01-01

    The selection of clonally-derived Chinese hamster ovary (CHO) cell lines with the highest production rate of recombinant glycoproteins remains a big challenge during early stages of cell line development. Different strategies using either product titer or product titer normalized to cell number...

  18. Technical objectives of inspection

    International Nuclear Information System (INIS)

    Sorenson, R.J.; Stewart, K.B.; Schneider, R.A.

    1976-01-01

    The various technical objectives of inspection are discussed in a very general manner. The discussion includes how the inspection function is related to the assumed threat, the various degrees of assurance and reliance on criteria, and the hierarchy of assurance which is obtained from the various types or levels of inspection

  19. Software Formal Inspections Guidebook

    Science.gov (United States)

    1993-01-01

    The Software Formal Inspections Guidebook is designed to support the inspection process of software developed by and for NASA. This document provides information on how to implement a recommended and proven method for conducting formal inspections of NASA software. This Guidebook is a companion document to NASA Standard 2202-93, Software Formal Inspections Standard, approved April 1993, which provides the rules, procedures, and specific requirements for conducting software formal inspections. Application of the Formal Inspections Standard is optional to NASA program or project management. In cases where program or project management decide to use the formal inspections method, this Guidebook provides additional information on how to establish and implement the process. The goal of the formal inspections process as documented in the above-mentioned Standard and this Guidebook is to provide a framework and model for an inspection process that will enable the detection and elimination of defects as early as possible in the software life cycle. An ancillary aspect of the formal inspection process incorporates the collection and analysis of inspection data to effect continual improvement in the inspection process and the quality of the software subjected to the process.

  20. Remote visual inspection of nuclear fuel pellets with fiber optics and video image processing

    International Nuclear Information System (INIS)

    Moore, F.W.

    1985-01-01

    Westinghouse Hanford Company has designed and is constructing a nuclear fuel fabrication process line for the Department of Energy. This process line includes a pellet surface inspection system that remotely inspects the cylindrical surface of nuclear fuel pellets for surface spots, flaws, or discoloration. The pellets are inspected on a 100% basis after pellet sintering. A feeder will deliver the pellets directly to fiber optic inspection head. The inspection head will view one pellet surface at a time. The surface image of the pellet will be imaged to a closed-circuit color television camera (CCTV). The output signal of the CCTV will be input to a digital imaging processor that stores approximately 25 pellet images at a time. A human operator will visually examine the images of the pellet surfaces on a high resolution monitor and accept or reject the pellets based on visual standards. The operator will use a digitizing tablet to record the location of rejected pellets, which will then be automatically removed from the product stream. The system is expandable to automated disposition of the pellet surface image

  1. Remote visual inspection of nuclear fuel pellets with fiber optics and video image processing

    International Nuclear Information System (INIS)

    Moore, F.W.

    1986-01-01

    Westinghouse Hanford Company has designed and is constructing a nuclear fuel fabrication process line for the Department of Energy. This process line includes a pellet surface inspection system that remotely inspects the cylindrical surface of nuclear fuel pellets for surface spots, flaws, or discoloration. The pellets are inspected on a 100 percent basis after pellet sintering. A feeder will deliver the pellets directly to a fiber optic inspection head. The inspection head will view one pellet surface at a time. The surface image of the pellet will be imaged to a closed-circuit color television camera (CCTV). The output signal of the CCTV will be input to a digital imaging processor that stores approximately 25 pellet images at a time. A human operator will visually examine the images of the pellet surfaces on a high resolution monitor and accept or reject the pellets based on visual standards. The operator will use a digitizing tablet to record the location of rejected pellets, which will then be automatically removed from the product stream. The system is expandable to automated disposition of the pellet surface image

  2. [Implementation of the HACCP system in the production line of the traditional sandwich in Phnom Penh City, Cambodia].

    Science.gov (United States)

    Lay, Kruy Sun; Song, Ping; Merch, Keuth; Sakona, Phoeurng; Buisson, Y

    2004-02-01

    From July 2000 to July 2001, the hazard analysis and critical control points (HACCP) system was implemented to the benefit of the traditional sandwich production in Phnom Penh City Sandwiches were initially analyzed for bacterial indicators among 6 large-scale producers during a 2 months period. In the second stage of the study, two selected producers were involved in the HACCP process. Microbiological analyses revealed a poor sanitary quality of samples from all the production lines tested. Implementation of HACCP method resulted in a reduction of microbial contamination, but this decrease was not significant compared with others steps of HACCP process (chi2 test for trend, p > 0.05). HACCP system was well accepted by producers but routine practices and wrong perception by production-line workers did limit the success of the process. A regulation on the mass catering sector should be part of a large strategy of food safety and environmental health in the city.

  3. Establishment of a high production system for AIDS retroviruses with a human T-leukemic cell line Molt-4

    International Nuclear Information System (INIS)

    Koyanagi, Yoshio; Harada, Shinji; Yamamoto, Naoki

    1986-01-01

    A cell culture system was developed for the continuous and efficient production of acquired immune deficiency syndrome (AIDS) retrovirus. After infection of a human T-cell line Molt-4 with HTLV-III and LAV the cells grow permanently and produce large amounts of virus continuously. The yields of production of virus were assessed either with reverse transcriptase activity or a newly established biological quantitation assay of active virus. The amounts of virus with this cell system were much higher than those of the H9 cell system. This procedure enabled us first to compare the two viral isolates HTLV-III and LAV directly in the same cell lines. Establishment of the culture system, allowing efficient production of AIDS retroviruses, provides a useful tool for the isolation of the virus from patients with AIDS and for more basic research, such as the mechanisms of immune destruction caused by the virus leading to the occurence of various malignancies (author)

  4. Identification and quantification of polycarboxylates in detergent products using off-line size exclusion chromatography-nuclear magnetic resonance

    Energy Technology Data Exchange (ETDEWEB)

    Visser, Ilona, E-mail: ilona.visser@unilever.com [Unilever Research and Development Vlaardingen, Olivier van Noortlaan 120, PO box 114, 3130 AC Vlaardingen (Netherlands); Klinkenberg, Monique; Hoos, Peter; Janssen, Hans-Gerd; Duynhoven, John van [Unilever Research and Development Vlaardingen, Olivier van Noortlaan 120, PO box 114, 3130 AC Vlaardingen (Netherlands)

    2009-11-03

    The performance of many contemporary detergent products critically depends on polymers. Water-soluble polycarboxylates represent an important class of detergent polymers, and their quantitative assessment in detergent matrices stands as a considerable challenge. The presence of high levels of surfactants is a major complication, due to the strong tendency of surfactants to form micelles and to interact with the polymers. First, we addressed critical steps in the subsequent combined use of liquid extraction and off-line size exclusion chromatography-nuclear magnetic resonance (SEC-NMR) for identification and quantification of polycarboxylates in detergent products. Next, the different steps in the off-line SEC-NMR procedure were optimized with respect to precision and accuracy. This resulted in recoveries of more than 80% for maleic acid/acrylic acid copolymers; in detergent products a proportional bias of 30% is achieved. The method showed good precision with a relative standard deviation of within-laboratory reproducibility between 5% and 14%.

  5. Identification and quantification of polycarboxylates in detergent products using off-line size exclusion chromatography-nuclear magnetic resonance

    International Nuclear Information System (INIS)

    Visser, Ilona; Klinkenberg, Monique; Hoos, Peter; Janssen, Hans-Gerd; Duynhoven, John van

    2009-01-01

    The performance of many contemporary detergent products critically depends on polymers. Water-soluble polycarboxylates represent an important class of detergent polymers, and their quantitative assessment in detergent matrices stands as a considerable challenge. The presence of high levels of surfactants is a major complication, due to the strong tendency of surfactants to form micelles and to interact with the polymers. First, we addressed critical steps in the subsequent combined use of liquid extraction and off-line size exclusion chromatography-nuclear magnetic resonance (SEC-NMR) for identification and quantification of polycarboxylates in detergent products. Next, the different steps in the off-line SEC-NMR procedure were optimized with respect to precision and accuracy. This resulted in recoveries of more than 80% for maleic acid/acrylic acid copolymers; in detergent products a proportional bias of 30% is achieved. The method showed good precision with a relative standard deviation of within-laboratory reproducibility between 5% and 14%.

  6. OSE inspection of computer security: Review

    International Nuclear Information System (INIS)

    Jaehne, E.M.

    1987-01-01

    The inspection process within the Department of Energy (DOE) serves the function of analyzing and reporting on the performance of security measures and controls in specific areas at sites throughout DOE. Three aspects of this process are discussed based on experience in computer security: Policy basis of performance inspections; Role and form of standards and criteria in inspections; and Conducting an inspection using the standards and criteria. Inspections are based on DOE and other applicable policy in each area. These policy statements have a compliance orientation in which the paper trail is often more clearly discernible than the security intention. The relationship of policy to performance inspections is discussed. To facilitate bridging the gap between the paper trail and the security intention defined by policy, standards and criteria were developed in each area. The consensus process and structure of the resulting product for computer security are discussed. Standards and criteria are inspection tools that support the site in preparing for an inspection and the inspector in conducting one. They form a systematic approach that facilitates consistency in the analysis and reporting of inspection results. Experience using the computer security standards and criteria is discussed

  7. Huh-7 cell line as an alternative cultural model for the production of human like erythropoietin (EPO

    Directory of Open Access Journals (Sweden)

    Kausar Humera

    2011-11-01

    Full Text Available Abstract Background and Aims Erythropoietin (EPO is a glycoprotein hormone which is required to regulate the production of red blood cells. Deficiency of EPO is known to cause anemia in chronically infected renal patients and they require regular blood transfusion. Availability of recombinant EPO has eliminated the need for blood transfusion and now it is extensively used for the treatment of anemia. Glycosylation of erythropoietin is essential for its secretion, stability, protein conformation and biological activity. However, maintenance of human like glycosylation pattern during manufacturing of EPO is a major challenge in biotechnology. Currently, Chinese hamster ovary (CHO cell line is used for the commercial production of erythropoietin but this cell line does not maintain glycosylation resembling human system. With the trend to eliminate non-human constituent from biopharmaceutical products, as a preliminary approach, we have investigated the potential of human hepatoma cell line (Huh-7 to produce recombinant EPO. Materials and methods Initially, the secretory signal and Kozak sequences was added before the EPO mature protein sequence using overlap extension PCR technique. PCR-amplified cDNA fragments of EPO was inserted into mammalian expression vector under the control of the cytomegalovirus (CMV promoter and transiently expressed in CHO and Huh-7 cell lines. After RT-PCR analysis, ELISA and Western blotting was performed to verify the immunochemical properties of secreted EPO. Results Addition of secretory signal and Kozak sequence facilitated the extra-cellular secretion and enhanced the expression of EPO protein. Significant expression (P Conclusion Huh-7 cell line has a great potential to produce glycosylated EPO, suggesting the use of this cell line to produce glycoproteins of the therapeutic importance resembling to the natural human system.

  8. How to inspect platform risers: an effective approach and new challenges

    International Nuclear Information System (INIS)

    Agthoven, Robert van

    2007-01-01

    Ageing risers on offshore platforms, designed and built several decades ago, were until recently hard to inspect or not inspectable at all. This was due to their layout or ID geometry changes prohibiting the use of product propelled intelligent pigs, which are frequently used, on long distance pipelines. Growing concerns about reliability and safety, as well as environmental pressure, are the impetus for operators of offshore platforms to check the condition of the risers, which until now could not be inspected. This paper describes a few solutions to enter these 'non-inspect-able' risers to check their condition by using special small diameter cable operated tools. These new miniature cable tools are spin-offs from the well-known cable (tether, umbilical) tools introduced more than two decades ago by RTD for the inspection of (off)-loading lines. The first generation gravity driven small diameter riser inspection tools were designed to inspect the vertical section of the riser only. On-going development has resulted in a second generation of riser inspection tools which can now enter a few hundred metres into the horizontal connecting pipeline on the sea-floor by using a small, but powerful, crawler. With this ability these tools are the only solution for riser-pipes and relatively short connecting pipelines which terminate at a T-or Y-connection in the vicinity of the platform. All riser inspection tools apply ultrasonics to quantify wall thickness and corrosion. A novel TOFD (Time Of Flight Diffraction) module can be applied as an option to inspect in the circumferential weld area. All cable tools have a reinforced cable, which is used for tool control and retrieval. A strong advantage of these cable tools is that they provide on-line results and allow on-site evaluation. Since the introduction of these new tools considerable experience has been gained. The history of development and several typical cases of applications are given in this paper. In addition

  9. Randomization of inspections

    International Nuclear Information System (INIS)

    Markin, J.T.

    1989-01-01

    As the numbers and complexity of nuclear facilities increase, limitations on resources for international safeguards may restrict attainment of safeguards goals. One option for improving the efficiency of limited resources is to expand the current inspection regime to include random allocation of the amount and frequency of inspection effort to material strata or to facilities. This paper identifies the changes in safeguards policy, administrative procedures, and operational procedures that would be necessary to accommodate randomized inspections and identifies those situations where randomization can improve inspection efficiency and those situations where the current nonrandom inspections should be maintained. 9 refs., 1 tab

  10. 75 FR 7563 - Certain Lined Paper Products from India: Notice of Final Results of Antidumping Duty...

    Science.gov (United States)

    2010-02-22

    ..., primarily suited for the recording of written numerical business data; lined business or office forms... polyolefin plastic material joined by 300 denier polyester, coated on the backside with PVC (poly vinyl...

  11. 77 FR 53174 - Certain Lined Paper Products From Indonesia: Revocation of Antidumping and Countervailing Duty...

    Science.gov (United States)

    2012-08-31

    ... recording of written numerical business data; Lined business or office forms, including but not limited to... material joined by 300 denier polyester, coated on the backside with PVC (poly vinyl chloride) coating, and...

  12. In vitro cytotoxicity of Indonesian stingless bee products against human cancer cell lines

    Directory of Open Access Journals (Sweden)

    Paula M. Kustiawan

    2014-07-01

    Conclusions: Propolis from T. incisa and Trigona fusco-balteata contain an in vitro cytotoxic activity against human cancer cell lines. Further study is required, including the isolation and characterization of the active antiproliferative agent(s.

  13. 9 CFR 590.128 - Holiday inspection service.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Holiday inspection service. 590.128... of Service § 590.128 Holiday inspection service. (a) When an official plant requires inspection service on a holiday or a day designated in lieu of a holiday, such service is considered holiday work...

  14. Production of reciprocal translocation lines and genetical analysis of tetravalent behavior in barley

    Energy Technology Data Exchange (ETDEWEB)

    Makino, Tokuhiko

    1988-03-01

    The seeds of a barley cultivar, Chikurinibaraki No.1 and of an early mutant line, Ea 52, derived from it were exposed to the external irradiation of gamma ray and thermal neutrons, and to the internal irradiation with the alpha ray from the nuclear reaction B-10 (n, alpha) Li-7 generated by the thermal neutron irradiation of B-10 imbibed seeds. The reciprocal translocation induced by these irradiation was detected and bred in the pedigrees of irradiated materials by the selection in terms of the partial sterility of seeds. The examination of seed fertility and chromosome pairing at the MI of meiosis of the F/sub 1/ hybrid between the selected lines and the original cultivar was also used. Consequently, 50 homozygous lines of reciprocal translocation were confirmed. The tester lines for translocated chromosomes were established by the cytological examination of the chromosome pairing in the hybrids between each two of the tester lines. The investigation of the inheritance of translocation heterozygotes showed that most of the newly obtained lines differently behaved from the expectation on the genetical basis of reciprocal translocation. (Kako, I.).

  15. Production of reciprocal translocation lines and genetical analysis of tetravalent behavior in barley

    International Nuclear Information System (INIS)

    Makino, Tokuhiko

    1988-01-01

    The seeds of a barley cultivar, Chikurinibaraki No.1 and of an early mutant line, Ea 52, derived from it were exposed to the external irradiation of gamma ray and thermal neutrons, and to the internal irradiation with the alpha ray from the nuclear reaction B-10 (n, alpha) Li-7 generated by the thermal neutron irradiation of B-10 imbibed seeds. The reciprocal translocation induced by these irradiation was detected and bred in the pedigrees of irradiated materials by the selection in terms of the partial sterility of seeds. The examination of seed fertility and chromosome pairing at the MI of meiosis of the F 1 hybrid between the selected lines and the original cultivar was also used. Consequently, 50 homozygous lines of reciprocal translocation were confirmed. The tester lines for translocated chromosomes were established by the cytological examination of the chromosome pairing in the hybrids between each two of the tester lines. The investigation of the inheritance of translocation heterozygotes showed that most of the newly obtained lines differently behaved from the expectation on the genetical basis of reciprocal translocation. (Kako, I.)

  16. Optical Inspection In Hostile Industrial Environments: Single-Sensor VS. Imaging Methods

    Science.gov (United States)

    Cielo, P.; Dufour, M.; Sokalski, A.

    1988-11-01

    On-line and unsupervised industrial inspection for quality control and process monitoring is increasingly required in the modern automated factory. Optical techniques are particularly well suited to industrial inspection in hostile environments because of their noncontact nature, fast response time and imaging capabilities. Optical sensors can be used for remote inspection of high temperature products or otherwise inaccessible parts, provided they are in a line-of-sight relation with the sensor. Moreover, optical sensors are much easier to adapt to a variety of part shapes, position or orientation and conveyor speeds as compared to contact-based sensors. This is an important requirement in a flexible automation environment. A number of choices are possible in the design of optical inspection systems. General-purpose two-dimensional (2-D) or three-dimensional (3-D) imaging techniques have advanced very rapidly in the last years thanks to a substantial research effort as well as to the availability of increasingly powerful and affordable hardware and software. Imaging can be realized using 2-D arrays or simpler one-dimensional (1-D) line-array detectors. Alternatively, dedicated single-spot sensors require a smaller amount of data processing and often lead to robust sensors which are particularly appropriate to on-line operation in hostile industrial environments. Many specialists now feel that dedicated sensors or clusters of sensors are often more effective for specific industrial automation and control tasks, at least in the short run. This paper will discuss optomechanical and electro-optical choices with reference to the design of a number of on-line inspection sensors which have been recently developed at our institute. Case studies will include real-time surface roughness evaluation on polymer cables extruded at high speed, surface characterization of hot-rolled or galvanized-steel sheets, temperature evaluation and pinhole detection in aluminum foil, multi

  17. Supply chain network downsizing with product line pruning using a new demand substitution

    NARCIS (Netherlands)

    Ashayeri, J.; Ma, N.; Sotirov, R.

    2015-01-01

    This paper presents an optimization model for downsizing a multi-product supply chain facing bankruptcy risk, where multi-functional production facilities are shared for producing a group of substitutable products. In order to determine the potential demand after discontinuation of certain product

  18. 76 FR 50998 - Certain Lined Paper Products From People's Republic of China: Initiation and Preliminary Results...

    Science.gov (United States)

    2011-08-17

    ...''). AASPS claims that producers accounting for substantially all of the production of the domestic like... definition, the actual use of or labeling these products as school supplies or non- school supplies is not a... determines that producers accounting for substantially all of the production of the domestic like product...

  19. Nuclear fuel shipping inspection device

    International Nuclear Information System (INIS)

    Takahashi, Toshio; Hada, Koji.

    1988-01-01

    Purpose: To provide an nuclear fuel shipping inspection device having a high detection sensitivity and capable of obtaining highly reliable inspection results. Constitution: The present invention concerns a device for distinguishing a fuel assembly having failed fuel rods in LMFBR type reactors. Coolants in a fuel assembly to be inspected are collected by a sampling pipeway and transferred to a filter device. In the filter device, granular radioactive corrosion products (CP) in the coolants are captured, to reduce the background. The coolants, after being passed through the filter device, are transferred to an FP catching device and gamma-rays of iodine and cesium nuclides are measured in FP radiation measuring device. Subsequently, the coolants transferred to a degasing device to separate rare gas FP in the coolants from the liquid phase. In a case if rare gas fission products are detected by the radiation detector, it means that there is a failed fuel rod in the fuel assembly to be inspected. Since the CP and the soluble FP are separated and extracted for the radioactivity measurement, the reliability can be improved. (Kamimura, M.)

  20. Development of Automated Production Line Processes for Solar Brightfield Modules: Annual Technical Progress Report, 1 January 2003 -- 30 June 2004

    Energy Technology Data Exchange (ETDEWEB)

    Nowlan, M. J.; Murach, J. M.; Sutherland, S. F.; Miller, D. C.; Moore, S. B.; Hogan, S. J.

    2005-06-01

    This report describes how Spire Corporation is addressing the PV Manufacturing R&D project goals of improving photovoltaic (PV) manufacturing processes and products while reducing costs and providing a technology foundation that supports significant manufacturing scale-up. To accomplish this, we are focusing our efforts on the design of a large-area utility-scale module and the development of the necessary manufacturing techniques and equipment to manufacture such a module in a high-volume production environment. A three-phase program is under way for developing and demonstrating new automated systems for fabricating very large PV modules ideal for use in multi-megawatt grid-connected applications. We designed a large-area 800 W module and we are developing associated module production equipment that will minimize the total installed system cost for utility-scale PV arrays. Unique features of the module design include a cantilevered glass superstrate to reduce the glass thickness a nd internally laminated bypass diodes that simplify internal busing and junction-box designs. Other program activities include the development of automation for solar cell string inspections, string busing, materials lay-up, and lamination; enhancements to the lamination process; and performance testing of large-area modules.

  1. 9 CFR 381.67 - Young chicken and squab slaughter inspection rate maximums under traditional inspection procedure.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Young chicken and squab slaughter... INSPECTION REGULATIONS Operating Procedures § 381.67 Young chicken and squab slaughter inspection rate... inspector per minute under the traditional inspection procedure for the different young chicken and squab...

  2. Bacteriological survey of frozen meat and gravy produced at establishments under federal inspection.

    Science.gov (United States)

    Surkiewicz, B F; Harris, M E; Johnston, R W

    1973-10-01

    During visits to 34 federally inspected establishments producing frozen meat and gravy, 541 production line samples and 535 finished product units were collected for bacteriological analyses. It was found that more than 70% of the sets of finished product (10 units/set) produced under good manufacturing practices had: (i) four or fewer coliform-positive units, (ii) two or fewer Escherichia coli-positive units, (iii) three or fewer Staphylococcus aureus-positive units, and (iv) an aerobic plate count of fewer than 50,000/g (geometric mean of 10 units). All finished product units were negative for salmonellae.

  3. Commercial nonindustrial production of pastries and ice cream in Naples, Italy: results from the inspection of 34 food businesses during a 2-year surveillance study

    Directory of Open Access Journals (Sweden)

    Lucia Tanucci Nannini

    2010-03-01

    Full Text Available

    Background: Ice cream and cream-based pastries are an excellent media for the growth of pathogenic microorganisms. Foods that are prepared without due respect to the rules of food hygiene can carry microorganisms and/or toxins and could be responsible of toxinfections. The main objective of this study was to obtain an overall picture of the hygiene/sanitation conditions found in businesses that produce hand-made pastries and/or ice cream in Naples, Italy.

    Methods: We inspected 34 businesses to assess the following aspects: hygiene/sanitation conditions of the work area and equipment, implementation of good food hygiene principles, evaluation of HACCP plans, licensing/authorization, quality control and sampling protocols, as well as systems for ensuring food traceability. In 28 of the businesses, samples (environment, foods, workers were collected for microbiological analysis.

    Results: Sanctions were issued for nonconformities in 8 businesses (23.5%, and 25 businesses (73.5% received warnings with orders to correct minor nonconformities (inadequate documentation of compliance with current regulations, incorrect implementation of the quality-control protocol within specified time periods. Microbiological analyses revealed irregularities in 24/28 businesses (85.7%, and 138 of the 280 samples collected displayed contamination levels exceeding the limits adopted for this study (49.3%. In particular, 80% of the surfaces sampled and 23.8% of the hand swabs collected were shown to be contaminated. All food samples collected met the process-hygiene and food-safety standards prescribed by the European Community. Results obtained were statistically significant (p < 0.05.

    Conclusions: Our experience of food safety surveillance system indicates that Neapolitan food business operators involved in the production of hand-made ice cream or pastries do not

  4. THE METHOD OF ROLL SURFACE QUALITY MEASUREMENT FOR CONTINUOUS HOT DIP ZINC COATED STEEL SHEET PRODUCTION LINE

    Directory of Open Access Journals (Sweden)

    Ki Yong Choi

    2015-01-01

    Full Text Available The present paper describes a developed analyzing system of roll surface during the process of continuous hot dip zinc coated steel sheet production line, in particular, adhering problem by transferred inclusions from roll to steel sheet surface during annealing process so called the pickup. The simulated test machine for coated roll surface in processing line has been designed and performed. The system makes it possible to analyze roll surface condition according to pickup phenomena from various roll coatings concerning operating conditions of hearth rolls in annealing furnace. The algorithm of fast pickup detection on surface is developed on the base of processing of several optical images of surface. The parameters for quality estimation of surface with pickups were developed. The optical system for images registration and image processing electronics may be used in real time and embed in processing line.

  5. Working group 8: inspection tools

    Energy Technology Data Exchange (ETDEWEB)

    Billey, Deb; Kania, Richard; Nickle, Randy; Wang, Rick; Westwood, Stephen

    2011-07-01

    This eighth working group of the Banff 2011 conference discussed the inspection tools and techniques used by the upstream and downstream pipeline industry to evaluate pipeline integrity. Special attention was given to the challenges and successes related to in-line inspection (ILI) technology. The background of current dent assessment criteria in B31.8 was presented, including dent definition for ILI vendors and pipeline operators as well as codes (CSA Z662 and B31.8). The workshop described examples of dents and assessments showing inconsistency with current criteria as set out by TCPL and Marathon. This workshop produced a single, industry-wide definition of the dent. It was found that the strain based criteria were more practical because depth based is conservative and may miss shallow occurrences. The creation of joint industry group was proposed to develop strain based criteria for incorporation into CSAZ662 and B31.8.

  6. Direction of glucose fermentation towards hydrogen or ethanol production through on-line pH control

    Energy Technology Data Exchange (ETDEWEB)

    Karadag, Dogan; Puhakka, Jaakko A. [Department of Chemistry and Bioengineering, Tampere University of Technology, Tampere (Finland)

    2010-10-15

    The present study investigated the production of hydrogen (H{sub 2}) and ethanol from glucose in an Anaerobic Continuous Stirred Tank Reactor (ACSTR). Effects of hydraulic retention time (HRT) and pH on the preference of producing H{sub 2} and/or ethanol and other soluble metabolic products in an open anaerobic enriched culture were studied. Production rates of H{sub 2} and ethanol increased with the increase of biomass concentration. Open anaerobic fermentation was directed and managed through on-line pH control for the production of H{sub 2} or ethanol. Hydrogen was produced by ethanol and acetate-butyrate type fermentations. pH has strong effect on the H{sub 2} or ethanol production by changing fermentation pathways. ACSTR produced mainly ethanol at over pH 5.5 whereas highest H{sub 2} production was obtained at pH 5.0. pH 4.9 favored the lactate production and accumulation of lactate inhibited the biomass concentration in the reactor and the production of H{sub 2} and ethanol. The microbial community structure quickly responded to pH changes and the Clostridia dominated in ACSTR during the study. H{sub 2} production was maintained mainly by Clostridium butyricum whereas in the presence of Bacillus coagulans glucose oxidation was directed to lactate production. (author)

  7. Evaluation of new hybrid brachiaria lines in Thailand. 1. Forage production and quality

    Directory of Open Access Journals (Sweden)

    Michael D. Hare

    2015-05-01

    Full Text Available Forty-three new hybrid bracharia lines were evaluated for forage accumulation and nutritive value in Northeast Thailand from 2006 to 2011 in experiments at 2 sites, using Mulato II hybrid brachiaria as a standard for comparison. The parameters evaluated were wet and dry season dry matter (DM accumulation, leaf:stem ratio, crude protein (CP concentration and fiber level [acid detergent fiber (ADF and neutral detergent fiber (NDF]. No lines consistently displayed superior dry season forage accumulation and leaf:stem ratio over Mulato II. In the wet seasons, 14 lines produced more DM than Mulato II but in only one wet season each. Mulato II produced forage with high leaf:stem ratio in all seasons. Many lines did have significantly higher CP concentrations and lower levels of ADF and NDF than Mulato II, but their forage accumulation and leaf:stem ratio were inferior. Four lines (BR02/1718, BR02/1752, BR02/1794 and BR02/0465 were granted Plant Variety Rights in 2011.Keywords: Cayman, Cobra, crude protein, dry matter yields, forage regrowth,  Mulato II.DOI: 10.17138/TGFT(383-93 

  8. COMPARISON AND INTERACTION GENOTIPE-ENVIRONMENT OF THE PRODUCTIVE PERFORMANCE IN THREE GENETIC LINES OF TILAPIA Oreochromis sp.

    Directory of Open Access Journals (Sweden)

    Jorge Luis Pérez-Fuentes

    2016-05-01

    Full Text Available Tilapia is the second most widely cultivated species in the international scope, due to their fast growing and breeding capacity in captivity. Its biggest problem is the unpredictability of the productive performance of varieties in different environments and management types. For this reason, the productive performance of three lines: Oreochromis niloticus (N, red Oreochromis mossambicus (M and Rocky Mountain (R, cultured in five sites in two environments (Presses: Miguel de la Madrid and Miguel Aleman in the State of Oaxaca, Mexico was compared. Cages with dimensions between 18 and 48 m3 with stocking density of 7 to 28 fish m-3 were used. Feeding varied depending on the producers (1 to 3 portions a day/cage (300 to 1200 g of feed. Total length (TL, weight (P, survival (SUP and fillet yield (RF were evaluated in each genetic line. Results from physicochemical parameters of water, environments of culture and production efficiency of the strains indicated no significant differences, except for weight gain (g between sites of culture. However, it was considered that the differences were mainly due to handling during the culture, rather than the genetic line. Genetic lines showed similar performance (Tilapia R: LT 16.5 ± 3.1 cm, P 99.0± 46.6 g, 28 % RF, SUP 91.6 %. Tilapia N: LT 16.7 ± 3.7 cm, P 98.2 ± 40.9, RF 23 % SUP 86 %. Tilapia M: LT 15.4 ± 4.6 cm, P 100.1 ± 112.5 g, 30 % RF, SUP 91.6 %. Under the conditions evaluated, type of management could influence the efficiency of the culture more than the genetic line.

  9. Production and identification of wheat - Agropyron cristatum (1.4P) alien translocation lines.

    Science.gov (United States)

    Liu, Wei-Hua; Luan, Yang; Wang, Jing-Chang; Wang, Xiao-Guang; Su, Jun-Ji; Zhang, Jin-Peng; Yang, Xin-Ming; Gao, Ai-Nong; Li, Li-Hui

    2010-06-01

    The P genome of Agropyron Gaertn., a wild relative of wheat, contains an abundance of desirable genes that can be utilized as genetic resources to improve wheat. In this study, wheat - Aegilops cylindrica Host gametocidal chromosome 2C addition lines were crossed with wheat - Agropyron cristatum (L.) Gaertn. disomic addition line accession II-21 with alien recombinant chromosome (1.4)P. We successfully induced wheat - A. cristatum alien chromosomal translocations for the first time. The frequency of translocation in the progeny was 3.75%, which was detected by molecular markers and genomic in situ hybridization (GISH). The translocation chromosomes were identified by dual-color GISH /fluorescence in situ hybridization (FISH). The P genomic DNA was used as probe to detect the (1.4)P chromosome fragment, and pHvG39, pAs1, or pSc119.2 repeated sequences were used as probes to identify wheat translocated chromosomes. The results showed that six types of translocations were identified in the three wheat - A. cristatum alien translocation lines, including the whole arm or terminal portion of a (1.4)P chromosome. The (1.4)P chromosome fragments were translocated to wheat chromosomes 1B, 2B, 5B, and 3D. The breakpoints were located at the centromeres of 1B and 2B, the pericentric locations of 5BS, and the terminals of 5BL and 3DS. In addition, we obtained 12 addition-deletion lines that contained alien A. cristatum chromosome (1.4)P in wheat background. All of these wheat - A. cristatum alien translocation lines and addition-deletion lines would be valuable for identifying A. cristatum chromosome (1.4)P-related genes and providing genetic resources and new germplasm accessions for the genetic improvement of wheat. The specific molecular markers of A. cristatum (1.4)P chromosome have been developed and used to track the (1.4)P chromatin.

  10. The gas-phase on-line production of vanadium oxytrihalides, VOX3 and their identification by infrared spectroscopy

    International Nuclear Information System (INIS)

    Zidan, M. D.; Allaf, A. W.

    2001-01-01

    A new route has been devised, leading to the production of VOX 3 molecules where X=F, Br and I by an on-line process using vanadium oxytrichloride, VOCl 3 as a starting compound passed over the following heated salts NaF, KBr and KI at 375, 700 and 550 centigrade, respectively. The products have been characterized by the IR spectra of their vapors. the low resolution gas phase on-line Fourier transform infrared spectra reported for the first time show strong bands with PQR type structure, centered at 1058, 1035, 1030 and 1025 cm -1 to the υ 1 (a 1 ), the O=V stretching fundamental mode of VOF 3 , VOCl 3 , VOBr 3 and VOI 3 , respectively. (Author)

  11. Noncontacting Optical Measurement And Inspection Systems

    Science.gov (United States)

    Asher, Jeffrey A.; Jackson, Robert L.

    1986-10-01

    Product inspection continues to play a growing role in the improvement of quality and reduction of scrap. Recent emphasis on precision measurements and in-process inspection have been a driving force for the development of noncontacting sensors. Noncontacting sensors can provide long term, unattended use due to the lack of sensor wear. Further, in applications where, sensor contact can damage or geometrically change the part to be measured or inspected, noncontacting sensors are the only technical approach available. MTI is involved in the development and sale of noncontacting sensors and custom inspection systems. This paper will review the recent advances in noncontacting sensor development. Machine vision and fiber optics sensor systems are finding a wide variety of industrial inspection applications. This paper will provide detailed examples of several state-of-the-art applications for these noncontacting sensors.

  12. Software product line engineering for consumer electronics : Keeping up with the speed of innovation

    NARCIS (Netherlands)

    Hartmann, Herman

    2015-01-01

    During the last decade consumer electronics products have changed radically. Traditionally these products were used for a few dedicated tasks, and were implemented through hardware. Nowadays, these products are used for a variety of tasks and are largely implemented through software. Furthermore

  13. Ergonomics Risk Assessment with Participation of Supervisors in Production Line: a Successful Experience in Pars Khodro Company

    OpenAIRE

    Adel Mazloumi; Seyed Hamid Reza Hosseini; Abdolsamad Ahmadvand; Zeinab Kazemi

    2014-01-01

    Background & Objectives: According to previous researches, workers' participation in issues affecting their working condition is the key to success in ergonomics interventions in working environments. Therefore, the present study was performed to increase active particapitation of supervisors in production line and also to identify and assess ergonomics risks and presenting modification actions (Kaizen) by themselves in Pars Khodro automobile manufacturing company. Methods: A manual regar...

  14. IL-4-producing murine T helper cell line provides help for in vitro production of IgE

    DEFF Research Database (Denmark)

    Poulsen, L K; Katamura, K; Ishizaka, K

    1991-01-01

    with nonadherent splenocytes from normal MHC-matched mice. Help provided by the antigen-stimulated T cell line induced significant IgE production (20 ng/ml), along with IgG1 (5 micrograms/ml) and IgM (250 micrograms/ml). Immunoglobulin synthesis in cultures was detectable at day 3-4 and culminated at day 7-8. IL-4...

  15. Screening and Selection of High Carotenoid Producing in Vitro Tomato Cell Culture Lines for [13C]-Carotenoid Production

    OpenAIRE

    Engelmann, Nancy J.; Campbell, Jessica K.; Rogers, Randy B.; Rupassara, S. Indumathie; Garlick, Peter J.; Lila, Mary Ann; Erdman, John W.

    2010-01-01

    Isotopically labeled tomato carotenoids, phytoene, phytofluene, and lycopene, are needed for mammalian bioavailability and metabolism research but are currently commercially unavailable. The goals of this work were to establish and screen multiple in vitro tomato cell lines for carotenoid production, test the best producers with or without the bleaching herbicides, norflurazon and 2-(4-chlorophenyl-thio)-triethylamine (CPTA), and to use the greatest carotenoid accumulator for in vitro 13C-lab...

  16. Generation and functional analysis of T cell lines and clones specific for schistosomula released products (SRP-A).

    Science.gov (United States)

    Damonneville, M; Velge, F; Verwaerde, C; Pestel, J; Auriault, C; Capron, A

    1987-01-01

    Antigens present in the products released by the larval stage of schistosome (SRP-A) were shown to induce a strong cytotoxic and protective IgE response both in the rat and the monkey. T cell lines and clones specific for SRP-A or 26 kD antigens which are the main target of the cytotoxic IgE have been derived. The passive transfer of SRP-A specific T lymphocytes into infected rats led to an increase of the IgE response, conferring a significant level of protection to the rats. In coculture assays in vitro, these cell lines significantly enhanced the production of IgE by SRP-A sensitized rat spleen cells. This helper effect on the IgE response was confirmed with 26 kD T cell clone supernatants. Moreover, supernatants obtained after stimulation with phorbol myristate acetate were able to enhance the IgE production of a hybridoma B cell line (B48-14) producing a monoclonal IgE antibody, cytotoxic for the schistosomula. PMID:3498590

  17. Generation and functional analysis of T cell lines and clones specific for schistosomula released products (SRP-A).

    Science.gov (United States)

    Damonneville, M; Velge, F; Verwaerde, C; Pestel, J; Auriault, C; Capron, A

    1987-08-01

    Antigens present in the products released by the larval stage of schistosome (SRP-A) were shown to induce a strong cytotoxic and protective IgE response both in the rat and the monkey. T cell lines and clones specific for SRP-A or 26 kD antigens which are the main target of the cytotoxic IgE have been derived. The passive transfer of SRP-A specific T lymphocytes into infected rats led to an increase of the IgE response, conferring a significant level of protection to the rats. In coculture assays in vitro, these cell lines significantly enhanced the production of IgE by SRP-A sensitized rat spleen cells. This helper effect on the IgE response was confirmed with 26 kD T cell clone supernatants. Moreover, supernatants obtained after stimulation with phorbol myristate acetate were able to enhance the IgE production of a hybridoma B cell line (B48-14) producing a monoclonal IgE antibody, cytotoxic for the schistosomula.

  18. Production and cytogenetics of Brassica campestris-alboglabra chromosome addition lines

    DEFF Research Database (Denmark)

    Chen, B.Y.; Cheng, B.F.; Bagger Jørgensen, Rikke

    1997-01-01

    Four different Brassica campestris-alboglabra monosomic addition lines (AA + 1 chromosome from C, 2n = 21) were obtained after consecutive backcrosses between resynthesized B. napus (AACC, 2n = 38) and the parental B. campestris (AA, 2n = 20) accession. The alien chromosomes of B. alboglabra (CC, 2...

  19. 77 FR 14729 - Certain Lined Paper Products From India: Notice of Final Results of Antidumping Duty...

    Science.gov (United States)

    2012-03-13

    ... covers, primarily suited for the recording of written numerical business data; Lined business or office... polyolefin plastic material joined by 300 denier polyester, coated on the backside with PVC (poly vinyl... Records Unit, main Commerce Building, Room 7046. In addition, a complete version of the Issues and...

  20. Method and cell lines for the production of monoclonal antibodies to human glycophorin A

    Science.gov (United States)

    Bigbee, W.L.; Fong, S.S.N.; Jensen, R.H.; Vanderlaan, M.

    Cloned mouse hybridoma cell lines have been established which continuously produce antibodies that differentiate between the M and N forms of human glycophorin A. These antibodies have potential application as human blood group reagents, as markers for terminally differentiated erythroid cells and as immunofluorescent labels of somatically variant human erythrocytes.