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Sample records for previously established techniques

  1. Establishment of SHG-44 human glioma model in brain of wistar rat with stereotactic technique

    International Nuclear Information System (INIS)

    Hong Xinyu; Luo Yi'nan; Fu Shuanglin; Wang Zhanfeng; Bie Li; Cui Jiale

    2004-01-01

    Objective: To establish solid intracerebral human glioma model in Wistar rat with xenograft methods. Methods: The SHG-44 cells were injected into brain right caudate nucleus of previous immuno-inhibitory Wistar rats with stereotactic technique. The MRI scans were performed at 1 week and 2 weeks later after implantation. After 2 weeks the rats were killed and pathological examination and immunohistologic stain for human GFAP were used. Results: The MRI scan after 1 week of implantation showed the glioma was growing, pathological histochemical examination demonstrated the tumor was glioma. Human GFAP stain was positive. The growth rate of glioma model was about 60%. Conclusion: Solid intracerebral human glioma model in previous immuno-inhibitory Wistar rat is successfully established

  2. The relationship between cerebrovascular complications and previously established use of antiplatelet therapy in left-sided infective endocarditis

    DEFF Research Database (Denmark)

    Snygg-Martin, Ulrika; Rasmussen, Rasmus Vedby; Hassager, Christian

    2011-01-01

    Cerebrovascular complications (CVC) in infective endocarditis (IE) are common. The only established treatments to reduce the incidence of CVC in IE are antibiotics and in selected cases early cardiac surgery. Potential effects of previously established antiplatelet therapy are under debate....

  3. Some views about PET technique establish and development

    International Nuclear Information System (INIS)

    Huang Zuhan

    2001-01-01

    About 2100 patients had been performed in Nanfang PET center since its establish in November, 1999. The clinical practice showed that the positron emission tomography (PET) had unique value for the diagnosis of malignancy, cardiac coronal artery disease, myocardium viability and for lesion localization of epilepsy and other cerebral function diseases. It had important impact to treatment of these diseases and improved the treatment outcomes of them. It also promoted the scientific studies and other correlative subjects and enhanced the station of nuclear medicine. Its integrative benefit was very great. In order to develop this technique more smoothly, authors would give the views on some questions such as how to look on PET images, its clinical value, its price and its cost-effectiveness. The authors would also give some proposal which could not be neglectable for establish of PET technique

  4. Technique for sparing previously irradiated critical normal structures in salvage proton craniospinal irradiation

    International Nuclear Information System (INIS)

    McDonald, Mark W; Wolanski, Mark R; Simmons, Joseph W; Buchsbaum, Jeffrey C

    2013-01-01

    Cranial reirradiation is clinically appropriate in some cases but cumulative radiation dose to critical normal structures remains a practical concern. The authors developed a simple technique in 3D conformal proton craniospinal irradiation (CSI) to block organs at risk (OAR) while minimizing underdosing of adjacent target brain tissue. Two clinical cases illustrate the use of proton therapy to provide salvage CSI when a previously irradiated OAR required sparing from additional radiation dose. The prior radiation plan was coregistered to the treatment planning CT to create a planning organ at risk volume (PRV) around the OAR. Right and left lateral cranial whole brain proton apertures were created with a small block over the PRV. Then right and left lateral “inverse apertures” were generated, creating an aperture opening in the shape of the area previously blocked and blocking the area previously open. The inverse aperture opening was made one millimeter smaller than the original block to minimize the risk of dose overlap. The inverse apertures were used to irradiate the target volume lateral to the PRV, selecting a proton beam range to abut the 50% isodose line against either lateral edge of the PRV. Together, the 4 cranial proton fields created a region of complete dose avoidance around the OAR. Comparative photon treatment plans were generated with opposed lateral X-ray fields with custom blocks and coplanar intensity modulated radiation therapy optimized to avoid the PRV. Cumulative dose volume histograms were evaluated. Treatment plans were developed and successfully implemented to provide sparing of previously irradiated critical normal structures while treating target brain lateral to these structures. The absence of dose overlapping during irradiation through the inverse apertures was confirmed by film. Compared to the lateral X-ray and IMRT treatment plans, the proton CSI technique improved coverage of target brain tissue while providing the least

  5. Development of an automation technique for the establishment of functional lipid bilayer arrays

    International Nuclear Information System (INIS)

    Hansen, J S; Vogel, J; Geschke, O; Emnéus, J; Nielsen, C H; Perry, M; Vissing, T; Hansen, C R

    2009-01-01

    In the present work, a technique for establishing multiple black lipid membranes (BLMs) in arrays of micro structured ethylene tetrafluoroethylene (ETFE) films, and supported by a micro porous material was developed. Rectangular 8 × 8 arrays with apertures having diameters of 301 ± 5 µm were fabricated in ETFE Teflon film by laser ablation using a carbon dioxide laser. Multiple lipid membranes could be formed across the micro structured 8 × 8 array ETFE partitions. Success rates for the establishment of cellulose-supported BLMs across the multiple aperture arrays were above 95%. However, the time course of the membrane thinning process was found to vary considerably between multiple aperture bilayer experiments. An airbrush partition pretreatment technique was developed to increase the reproducibility of the multiple lipid bilayers formation during the time course from the establishment of the lipid membranes to the formation of bilayers. The results showed that multiple lipid bilayers could be reproducible formed across the airbrush-pretreated 8 × 8 rectangular arrays. The ionophoric peptide valinomycin was incorporated into established membrane arrays, resulting in ionic currents that could be effectively blocked by tetraethylammonium. This shows that functional bimolecular lipid membranes were established, and furthermore outlines that the established lipid membrane arrays could host functional membrane-spanning molecules

  6. A new cerebral vasospasm model established with endovascular puncture technique

    International Nuclear Information System (INIS)

    Tu Jianfei; Liu Yizhi; Ji Jiansong; Zhao Zhongwei

    2011-01-01

    Objective: To investigate the method of establishing cerebral vasospasm (CVS) models in rabbits by using endovascular puncture technique. Methods: Endovascular puncture procedure was performed in 78 New Zealand white rabbits to produce subarachnoid hemorrhage (SAH). The survival rabbits were randomly divided into seven groups (3 h, 12 h, 1 d, 2 d, 3 d, 7 d and 14 d), with five rabbits in each group for both study group (SAH group) and control group. Cerebral CT scanning was carried out in all rabbits both before and after the operation. The inner diameter and the thickness of vascular wall of both posterior communicating artery (PcoA) and basilar artery (BA) were determined after the animals were sacrificed, and the results were analyzed. Results: Of 78 experimental rabbits, CVS model was successfully established in 45, including 35 of SAH group and 10 control subgroup. The technical success rate was 57.7%. Twelve hours after the procedure, the inner diameter of PcoA and BA in SAH group was decreased by 45.6% and 52.3%, respectively, when compared with these in control group. The vascular narrowing showed biphasic changes, the inner diameter markedly decreased again at the 7th day when the decrease reached its peak to 31.2% and 48.6%, respectively. Conclusion: Endovascular puncture technique is an effective method to establish CVS models in rabbits. The death rate of experimental animals can be decreased if new interventional material is used and the manipulation is carefully performed. (authors)

  7. Establishment techniques in under-sown perennial ryegrass for seed production

    DEFF Research Database (Denmark)

    Deleuran, Lise C; Boelt, Birte

    2009-01-01

    Establishment methods have proven to be of major importance for grass-seed production. The objective of this research was to test the effect of different sowing techniques on plant establishment and the subsequent seed yield. Perennial ryegrass (Lolium perenne L.) is used as the model grass due...... to its large importance in Danish agriculture. In a three-year trial six different methods of under-sowing of perennial ryegrass in a spring barley cover crop were employed. Perennial ryegrass was either sown directly at different depths within the spring barley (Hordeum vulgare L.) rows or placed 2, 6......, or 12 cm from the spring barley rows. Results of dry-matter yield indicate that the best establishment of the grass occurred when placing the grass 6 or 12 cm from the cover-crop row, and this is of importance in less vigorous grasses. Overall, no seed-yield difference has been observed for perennial...

  8. Establishment of Measurement Techniques for Sliding Bubble on a Horizontal Tube

    International Nuclear Information System (INIS)

    Kim, Yu-Na Kim; Park, Goon-Cherl; Cho, Hyoung-Kyu

    2015-01-01

    The mechanistic wall boiling model includes many parameters relevant with bubble behaviors, such as the bubble departure diameter, bubble lift-off diameter, bubble waiting time, etc. Although there have been a large number of studies investigating bubble behavior, the subjects of observation are almost bubbles on a plane or vertical tube. Since the bubble motion is highly influenced by the directions of gravitational force and the heating surfaces, it is expected that the bubble behavior on a horizontal tube is largely different from those on the other geometry. The heat exchanger of APR+ has horizontal U-tube configuration installed in a water pool, of which diameter is 50mm. The study aims to establish measurement techniques for sliding bubbles on a horizontal tube. The measurement parameters include the diameter, interface area, volume, and velocity of the bubble. Additionally, in order to analyze the force acting on the bubble, liquid velocity measurement method was proposed. This paper presents the procedure of the measurement; the phase separation technique, 3-D reconstruction technique, and velocity measurement techniques. For visualization of the sliding bubble behavior, bubble and liquid velocity measurement methods were established which use two high speed cameras and a continuous LASER for the PTV and PIV. Three steps for the bubble shape and velocity measurement (the phase separation, 3-D reconstruction, and velocity calculation), were successfully set up and verified. A PIV technique which uses two different time duration for two regions where the velocity difference is huge was proposed and tested. Using these methods, various information regarding a sliding bubble can be obtained such as bubble and liquid velocities, shape, volume, surface area etc

  9. Insertion of central venous catheters for hemodialysis using angiographic techniques in patients with previous multiple catheterizations

    Energy Technology Data Exchange (ETDEWEB)

    Kotsikoris, Ioannis, E-mail: gkotsikoris@gmail.com [Department of Vascular Surgery, “Erythros Stauros” General Hospital (Greece); Zygomalas, Apollon, E-mail: azygomalas@upatras.gr [Department of General Surgery, University Hospital of Patras (Greece); Papas, Theofanis, E-mail: pfanis@otenet.gr [Department of Vascular Surgery, “Erythros Stauros” General Hospital (Greece); Maras, Dimitris, E-mail: dimmaras@gmail.com [Department of Vascular Surgery, “Erythros Stauros” General Hospital (Greece); Pavlidis, Polyvios, E-mail: polpavlidis@yahoo.gr [Department of Vascular Surgery, “Erythros Stauros” General Hospital (Greece); Andrikopoulou, Maria, E-mail: madric@gmail.com [Department of Vascular Surgery, “Erythros Stauros” General Hospital (Greece); Tsanis, Antonis, E-mail: atsanis@gmail.com [Department of Interventional Radiology, “Erythros Stauros” General Hospital (Greece); Alivizatos, Vasileios, E-mail: valiviz@hol.gr [Department of General Surgery and Artificial Nutrition Unit, “Agios Andreas” General Hospital of Patras (Greece); Bessias, Nikolaos, E-mail: bessias@otenet.gr [Department of Vascular Surgery, “Erythros Stauros” General Hospital (Greece)

    2012-09-15

    Introduction: Central venous catheter placement is an effective alternative vascular access for dialysis in patients with chronic renal failure. The purpose of this study was to evaluate the insertion of central venous catheters for hemodialysis using angiographic techniques in patients with previous multiple catheterizations in terms of efficacy of the procedure and early complications. Materials and methods: Between 2008 and 2010, the vascular access team of our hospital placed 409 central venous catheters in patients with chronic renal failure. The procedure was performed using the Seldinger blind technique. In 18 (4.4%) cases it was impossible to advance the guidewire, and so the patients were transported to the angiography suite. Results: Using the angiographic technique, the guidewire was advanced in order to position the central venous catheter. The latter was inserted into the subclavian vein in 12 (66.6%) cases, into the internal jugular vein in 4 (22.2%) and into the femoral vein in 2 (11.1%) cases. There was only one complicated case with severe arrhythmia in 1 (5.5%) patient. Conclusion: Our results suggest that insertion of central venous catheters using angiographic techniques in hemodialysis patients with previous multiple catheterizations is a safe and effective procedure with few complications and high success rates.

  10. Insertion of central venous catheters for hemodialysis using angiographic techniques in patients with previous multiple catheterizations

    International Nuclear Information System (INIS)

    Kotsikoris, Ioannis; Zygomalas, Apollon; Papas, Theofanis; Maras, Dimitris; Pavlidis, Polyvios; Andrikopoulou, Maria; Tsanis, Antonis; Alivizatos, Vasileios; Bessias, Nikolaos

    2012-01-01

    Introduction: Central venous catheter placement is an effective alternative vascular access for dialysis in patients with chronic renal failure. The purpose of this study was to evaluate the insertion of central venous catheters for hemodialysis using angiographic techniques in patients with previous multiple catheterizations in terms of efficacy of the procedure and early complications. Materials and methods: Between 2008 and 2010, the vascular access team of our hospital placed 409 central venous catheters in patients with chronic renal failure. The procedure was performed using the Seldinger blind technique. In 18 (4.4%) cases it was impossible to advance the guidewire, and so the patients were transported to the angiography suite. Results: Using the angiographic technique, the guidewire was advanced in order to position the central venous catheter. The latter was inserted into the subclavian vein in 12 (66.6%) cases, into the internal jugular vein in 4 (22.2%) and into the femoral vein in 2 (11.1%) cases. There was only one complicated case with severe arrhythmia in 1 (5.5%) patient. Conclusion: Our results suggest that insertion of central venous catheters using angiographic techniques in hemodialysis patients with previous multiple catheterizations is a safe and effective procedure with few complications and high success rates

  11. Development of an Automation Technique for the Establishment of Functional Lipid Bilayer Arrays

    DEFF Research Database (Denmark)

    Hansen, Jesper Søndergaard; Perry, Mark; Vogel, Jörg

    2009-01-01

    In the present work, a technique for establishing multiple black lipid membranes (BLMs) in arrays of micro structured ethylene tetrafluoroethylene (ETFE) films, and supported by a micro porous material was developed. Rectangular 8 x 8 arrays with apertures having diameters of 301 +/- 5 mu m were...

  12. Aerobic rice mechanization: techniques for crop establishment

    Science.gov (United States)

    Khusairy, K. M.; Ayob, H.; Chan, C. S.; Fauzi, M. I. Mohamed; Mohamad Fakhrul, Z. O.; Shahril Shah, G. S. M.; Azlan, O.; Rasad, M. A.; Hashim, A. M.; Arshad, Z.; E, E. Ibrahim; Saifulizan, M. N.

    2015-12-01

    Rice being the staple food crops, hundreds of land races in it makes the diversity of rice crops. Aerobic rice production was introduced which requires much less water input to safeguard and sustain the rice production and conserve water due to decreasing water resources, climatic changes and competition from urban and industrial users. Mechanization system plays an important role for the success of aerobic rice cultivation. All farming activities for aerobic rice production are run on aerobic soil conditions. Row seeder mechanization system is developed to replace conventional seeding technique on the aerobic rice field. It is targeted for small and the large scale aerobic rice farmers. The aero - seeder machine is used for the small scale aerobic rice field, while the accord - seeder is used for the large scale aerobic rice field. The use of this mechanization machine can eliminate the tedious and inaccurate seeding operations reduce labour costs and increases work rate. The machine is easy to operate and it can increase crop establishment rate. It reduce missing hill, increasing planting and crop with high yield can be produce. This machine is designed for low costs maintenance and it is easy to dismantle and assemble during maintenance and it is safe to be used.

  13. Indications and technique of fetal magnetic resonance imaging

    International Nuclear Information System (INIS)

    Asenbaum, U.; Woitek, R.; Furtner, J.; Prayer, D.; Brugger, P.C.

    2013-01-01

    Evaluation and confirmation of fetal pathologies previously suspected or diagnosed with ultrasound. Ultrasound and magnetic resonance imaging (MRI). Technique for prenatal fetal examination. Fetal MRI is an established supplementary technique to prenatal ultrasound. Fetal MRI should only be used as an additional method in prenatal diagnostics and not for routine screening. Fetal MRI should only be performed in perinatal medicine centers after a previous level III ultrasound examination. (orig.) [de

  14. Establishment of atherosclerotic model and USPIO enhanced MRI techniques study in rabbits

    International Nuclear Information System (INIS)

    Li Yonggang; Zhu Mo; Dai Yinyu; Chen Jianhua; Guo Liang; Ni Jiankun

    2010-01-01

    Objective: To explore the methods of establishment of atherosclerotic model and USPIO enhanced MRI techniques in rabbits. Methods: Thirty New Zealand male rabbits were divided randomly into two groups: 20 animals in the experiment group, 10 animals in the control group. Animal model of atherosclerosis was induced with aortic balloon endothelial injury and high-fat diet feeding. There was no intervention with the rabbits in control group. MRI examination included plan scan, USPIO enhanced black-blood sequences and white-blood sequence. The features of the plaques was analyzed in the experimental group and the effection on the image quality of different coils, sequences and parameters and a statistical study was also analyzed. Results: Animal model of atherosclerosis was successfully made in 12 rabbits and most plaques located in the abdomen aorta. There were 86 plaques within the scanning scope among which 67 plaques were positive to the Prussian blue staining. The image quality of knee joint coil was better than that of other coils. Although there was no difference in the detection of numbers of AS plaques between USPIO enhanced black-blood sequences and white-blood sequence (P > 0.05), blackblood sequences was superior to white-blood sequence in the demonstration of the components of plaque. Conclusion: The method of aortic balloon endothelial injury and high-fat diet feeding can easily establish the AS model in rabbits with a shorter period and it may be used for controlling the location of the plaques. USPIO enhanced MRI sequences has high sensitivity in the detection of the AS plauqes and can reveal the component of AS plaques. The optimization of MRI techniques is very important in the improvement of the image quality and the detection of the plaques. (authors)

  15. Alkylation induced cerebellar degeneration dependent on Aag and Parp1 does not occur via previously established cell death mechanisms.

    Directory of Open Access Journals (Sweden)

    Carrie M Margulies

    Full Text Available Alkylating agents are ubiquitous in our internal and external environments, causing DNA damage that contributes to mutations and cell death that can result in aging, tissue degeneration and cancer. Repair of methylated DNA bases occurs primarily through the base excision repair (BER pathway, a multi-enzyme pathway initiated by the alkyladenine DNA glycosylase (Aag, also known as Mpg. Previous work demonstrated that mice treated with the alkylating agent methyl methanesulfonate (MMS undergo cerebellar degeneration in an Aag-dependent manner, whereby increased BER initiation by Aag causes increased tissue damage that is dependent on activation of poly (ADP-ribose polymerase 1 (Parp1. Here, we dissect the molecular mechanism of cerebellar granule neuron (CGN sensitivity to MMS using primary ex vivo neuronal cultures. We first established a high-throughput fluorescent imaging method to assess primary neuron sensitivity to treatment with DNA damaging agents. Next, we verified that the alkylation sensitivity of CGNs is an intrinsic phenotype that accurately recapitulates the in vivo dependency of alkylation-induced CGN cell death on Aag and Parp1 activity. Finally, we show that MMS-induced CGN toxicity is independent of all the cellular events that have previously been associated with Parp-mediated toxicity, including mitochondrial depolarization, AIF translocation, calcium fluxes, and NAD+ consumption. We therefore believe that further investigation is needed to adequately describe all varieties of Parp-mediated cell death.

  16. Alkylation induced cerebellar degeneration dependent on Aag and Parp1 does not occur via previously established cell death mechanisms.

    Science.gov (United States)

    Margulies, Carrie M; Chaim, Isaac Alexander; Mazumder, Aprotim; Criscione, June; Samson, Leona D

    2017-01-01

    Alkylating agents are ubiquitous in our internal and external environments, causing DNA damage that contributes to mutations and cell death that can result in aging, tissue degeneration and cancer. Repair of methylated DNA bases occurs primarily through the base excision repair (BER) pathway, a multi-enzyme pathway initiated by the alkyladenine DNA glycosylase (Aag, also known as Mpg). Previous work demonstrated that mice treated with the alkylating agent methyl methanesulfonate (MMS) undergo cerebellar degeneration in an Aag-dependent manner, whereby increased BER initiation by Aag causes increased tissue damage that is dependent on activation of poly (ADP-ribose) polymerase 1 (Parp1). Here, we dissect the molecular mechanism of cerebellar granule neuron (CGN) sensitivity to MMS using primary ex vivo neuronal cultures. We first established a high-throughput fluorescent imaging method to assess primary neuron sensitivity to treatment with DNA damaging agents. Next, we verified that the alkylation sensitivity of CGNs is an intrinsic phenotype that accurately recapitulates the in vivo dependency of alkylation-induced CGN cell death on Aag and Parp1 activity. Finally, we show that MMS-induced CGN toxicity is independent of all the cellular events that have previously been associated with Parp-mediated toxicity, including mitochondrial depolarization, AIF translocation, calcium fluxes, and NAD+ consumption. We therefore believe that further investigation is needed to adequately describe all varieties of Parp-mediated cell death.

  17. Establishment of a Pcr Technique for Determination of Htlv-1 Infection in Paraffin-Embedded Tissues

    Directory of Open Access Journals (Sweden)

    M Rastin

    2007-04-01

    Full Text Available Introduction: HTLV-1 , the first known human retrovirus belongs to oncovirus subfamily of retroviruses. The major characteristic of HTLV-1 is its highly restricted geographic prevalence. Northern part of Khorasan is an endemic region of HTLV-1 infection. Epidemiological studies can help in designing preventive programs for HTLV-1 infection. The aim of this study was the establishment of a PCR technique for determination of HTLV-1 infection in paraffin-embedded tissues. Methods: In this experimental laboratory study for establishment of a technique, PCR was initially optimized using Beta-actin primers on various formalin fixed paraffin-embedded tissues from liver, spleen, skin and lymph nodes. The optimized concentration of Mgcl2 was 2mm, primer was 8 pmol. Optimized concentration of DNA was different according to the kind of tissue. HTLV-1 infection was determined by applying tax, pol, env and LTR primers on 50 paraffin-embedded lymph node tissues . The reporoducibility of this technique was shown for skin and lymph node tissues infected with HTLV-1. Resuls: In 50 lymph node tissues, one case with pathologic diagnosis of NHL was positive with all 5 sets of primers (tax, Pol, env and LTR primers and the other case was positive with only two sets of tax primers but was negative with pol, env and LTR primers. The prevalence of infection was 2% among lymph node specimens. (1 of 50 specimens and if the second case is considered, the prevalence would be 4%. Conclusion: Comparison of the results of this study with another study on blood specimens (seroprevalence2.3% was not statistically significant thus confirming the results of one another. (P=0.883

  18. Immediate breast reconstruction after skin- or nipple-sparing mastectomy for previously augmented patients: a personal technique.

    Science.gov (United States)

    Salgarello, Marzia; Rochira, Dario; Barone-Adesi, Liliana; Farallo, Eugenio

    2012-04-01

    Breast reconstruction for previously augmented patients differs from breast reconstruction for nonaugmented patients. Many surgeons regard conservation therapy as not feasible for these patients because of implant complications, whether radiotherapy-induced or not. Despite this, most authors agree that mastectomy with immediate breast reconstruction is the most suitable choice, ensuring both a good cosmetic result and a low complication rate. Implant retention or removal remains a controversial topic in addition to the best available surgical technique. This study reviewed the authors' experience with immediate breast reconstruction after skin-sparing mastectomy (SSM) and nipple-sparing mastectomy (NSM) with anatomically definitive implants. The retrospective records of 12 patients were examined (group A). These patients were among 254 patients who underwent SSM or NSM for breast carcinoma. The control group comprised 12 of the 254 patients submitted to SSM or NSM (group B) who best matched the 12 patients in the studied group. All of them underwent immediate breast reconstruction, with an anatomically definitive implant placed in a submuscular-subfascial pocket. The demographic, technical, and oncologic data of the two groups were compared as well as the aesthetic outcomes using the Breast Q score. The proportion of complications, the type of implant, the axillary lymph node procedure, and the histology were compared between the two groups using Fisher's exact test. Student's t test was used to compare the scores for the procedure-specific modules of the breast Q questionnaire in the two groups. A validated patient satisfaction score was obtained using the breast Q questionnaire after breast reconstruction. The demographic, technical, and oncologic characteristics were not significantly different between the two groups. The previously augmented patients reported a significantly higher level of satisfaction with their breast than the control patients. The scores

  19. Techniques for combining isotopic images obtained at different energies

    International Nuclear Information System (INIS)

    Soussaline, F.; Di Paola, R.; Bazin, J.P.

    1976-01-01

    The technique described should be considered as a first step towards the classification of scintigraphic data where the energy is included. As in all such studies the interpretation of the resulting images is not necessarily at first evident, and certain experience needs to be established. This applies in particular to the images obtained with the higher factors. It is possible that the use of this technique may resolve, without requiring a priori information, the problem previously encountered using the other 'subtraction' type techniques [fr

  20. Learning Recruits Neurons Representing Previously Established Associations in the Corvid Endbrain.

    Science.gov (United States)

    Veit, Lena; Pidpruzhnykova, Galyna; Nieder, Andreas

    2017-10-01

    Crows quickly learn arbitrary associations. As a neuronal correlate of this behavior, single neurons in the corvid endbrain area nidopallium caudolaterale (NCL) change their response properties during association learning. In crows performing a delayed association task that required them to map both familiar and novel sample pictures to the same two choice pictures, NCL neurons established a common, prospective code for associations. Here, we report that neuronal tuning changes during learning were not distributed equally in the recorded population of NCL neurons. Instead, such learning-related changes relied almost exclusively on neurons which were already encoding familiar associations. Only in such neurons did behavioral improvements during learning of novel associations coincide with increasing selectivity over the learning process. The size and direction of selectivity for familiar and newly learned associations were highly correlated. These increases in selectivity for novel associations occurred only late in the delay period. Moreover, NCL neurons discriminated correct from erroneous trial outcome based on feedback signals at the end of the trial, particularly in newly learned associations. Our results indicate that task-relevant changes during association learning are not distributed within the population of corvid NCL neurons but rather are restricted to a specific group of association-selective neurons. Such association neurons in the multimodal cognitive integration area NCL likely play an important role during highly flexible behavior in corvids.

  1. Establishing Food Traceability System Using Nuclear and Related Techniques in Malaysia

    International Nuclear Information System (INIS)

    Zainon Othman; Nazaratul Ashifa Abdullah Salim; Salmah Moosa; Roslanzairi Mostapha

    2015-01-01

    Determination of food traceability is important in quality control and safety of food. The dramatic increase in the volume of global trade and complexity of supply chains has caused a number of issues concerning food authenticity and safety. Commodities that attract premium prices are subject to fraud such as adulteration and counterfeit. This poses serious health risks due to unknown origin of the counterfeit. In addition to safety concern, the capability to certify food origin is becoming significant economic importance. In several countries, the use of geographical indications allows producers to obtain market recognition and often a premium price. In addressing food safety issues in Malaysia, the Food Hygiene Regulations (2009) has provision for traceability but mechanism on how traceability can be achieved is not prescribed. Present mechanism is mainly paper-based system that passes information along with the commodity. However, such system is subject to failure either inadvertently or deliberately (fraud). Thus there is a need to establish a science-based traceability system to support the food safety surveillance program in Malaysia. This paper presents the concept and use of nuclear and related techniques involving isotopic and elemental fingerprinting in determining the geographical origin of various food products and its potential application for traceability of Malaysian agricultural produce. (author)

  2. Laparoscopy After Previous Laparotomy

    Directory of Open Access Journals (Sweden)

    Zulfo Godinjak

    2006-11-01

    Full Text Available Following the abdominal surgery, extensive adhesions often occur and they can cause difficulties during laparoscopic operations. However, previous laparotomy is not considered to be a contraindication for laparoscopy. The aim of this study is to present that an insertion of Veres needle in the region of umbilicus is a safe method for creating a pneumoperitoneum for laparoscopic operations after previous laparotomy. In the last three years, we have performed 144 laparoscopic operations in patients that previously underwent one or two laparotomies. Pathology of digestive system, genital organs, Cesarean Section or abdominal war injuries were the most common causes of previouslaparotomy. During those operations or during entering into abdominal cavity we have not experienced any complications, while in 7 patients we performed conversion to laparotomy following the diagnostic laparoscopy. In all patients an insertion of Veres needle and trocar insertion in the umbilical region was performed, namely a technique of closed laparoscopy. Not even in one patient adhesions in the region of umbilicus were found, and no abdominal organs were injured.

  3. Junk-food enhances conditioned food cup approach to a previously established food cue, but does not alter cue potentiated feeding; implications for the effects of palatable diets on incentive motivation.

    Science.gov (United States)

    Derman, Rifka C; Ferrario, Carrie R

    2018-03-16

    Efforts to stem the global rise in obesity have been minimally effective, perhaps in part because our understanding of the psychological and behavioral drivers of obesity is limited. It is well established that stimuli that are paired with palatable foods can powerfully influence food-seeking and feeding behaviors. However, how consumption of sugary, fatty "junk-foods" affects these motivational responses to food cues is poorly understood. Here, we determined the effects of short- and long-term "junk-food" consumption on the expression of cue potentiated feeding and conditioned food cup approach to Pavlovian conditioned stimuli (CS). Further, to determine the degree to which effects of "junk-food" were selective to Pavlovian motivational processes, we varied the predictive validity of the CS by including training groups conditioned with unique CS-US contingencies ranging from -1.0 to +1.0. "Junk-food" did not enhance cue potentiated feeding in any group, but expression of this potentiation effect varied with the CS-US contingency independent of diet. In contrast, "junk-food" consistently enhanced conditioned approach to the food cup; this effect was dependent on the previously established CS-US contingency. That is, consumption of "junk-food" following training enhanced approach to the food cup only in response to CSs with previously positive CS-US contingencies. This was accompanied by reduced motivation for the US itself. Together these data show that "junk-food" consumption selectively enhances incentive motivational responses to previously established food CSs, without altering cue potentiated feeding induced by these same CSs, and in the absence of enhanced motivation for food itself. Copyright © 2018 Elsevier Inc. All rights reserved.

  4. Establishment of 60Co dose calibration curve using fluorescent in situ hybridization assay technique: Result of preliminary study

    International Nuclear Information System (INIS)

    Rahimah Abdul Rahim; Noriah Jamal; Noraisyah Mohd Yusof; Juliana Mahamad Napiah; Nelly Bo Nai Lee

    2010-01-01

    This study aims at establishing an in-vitro 60 Co dose calibration curve using Fluorescent In-Situ Hybridization assay technique for the Malaysian National Bio dosimetry Laboratory. Blood samples collected from a female healthy donor were irradiated with several doses of 60 Co radiation. Following culturing of lymphocytes, microscopic slides are prepared, denatured and hybridized. The frequencies of translocation are estimated in the metaphases. A calibration curve was then generated using a regression technique. It shows a good fit to a linear-quadratic model. The results of this study might be useful in estimating absorbed dose for the individual exposed to ionizing radiation retrospectively. This information may be useful as a guide for medical treatment for the assessment of possible health consequences. (author)

  5. THE PERFORMANCE OF SOYBEAN (c.v. Americana ESTABLISHED BY ZERO TILLAGE TECHNIQUE IN IMPERATA FIELD CONTROLLED BY HERBICIDES

    Directory of Open Access Journals (Sweden)

    S. TJITROSEMITO

    1989-01-01

    Full Text Available A field experiment was conducted to investigate the performance of soybean (c.v. Americana when established with zero tillage technique on Imperata dominated area. Four different techniques of alang-alang control i.e. imazapyr (20 kg ai/ha, glyphosate (25 kg ai/ha, glufosinate (3.0 kg ai/ha and manual cultivation were arranged factorially with time of plantings i.e. 1,2 and 3 months after treatments. The alang-alang damages varied with herbicides and times, imazapyr (20 kg ai/ha showed slow appearance of damage at 3 months after application it was only 69%, while that of glufosinate was already down to 48% due to regrowth. No phytotoxicity was recorded, but the yield was low.

  6. A stimulus control technique for improving the efficacy of an established toilet training program.

    Science.gov (United States)

    Taylor, S; Cipani, E; Clardy, A

    1994-06-01

    Standard toilet training regimens used with children with developmental disabilities have demonstrated effectiveness at achieving bladder and bowel continence. However, in some clinical applications in everyday practice, success has not been achieved, necessitating research into possible modifications of the current approaches. A widely used toilet training program was modified to reduce toileting accidents of a referred child. The modification involved the assessment of the discriminative stimulus for eliminating, namely, his undergarments. By removing the undergarments when an elimination became imminent, an "errorless" learning paradigm was established that allowed for more rapid and enduring acquisition of toileting skills than seen in previous training attempts. The results indicate the present procedure could expedite training for individuals who are difficult to teach appropriate toileting skills through an analysis of the controlling antecedent stimulus for accidents and subsequent manipulation of such stimuli.

  7. Standard Establishment Through Scenarios (SETS): A new technique for occupational fitness standards.

    Science.gov (United States)

    Blacklock, R E; Reilly, T J; Spivock, M; Newton, P S; Olinek, S M

    2015-01-01

    An objective and scientific task analysis provides the basis for establishing legally defensible Physical Employment Standards (PES), based on common and essential occupational tasks. Infrequent performance of these tasks creates challenges when developing PES based on criterion, or content validity. Develop a systematic approach using Subject Matter Experts (SME) to provide tasks with 1) an occupationally relevant scenario considered common to all personnel; 2) a minimum performance standard defined by time, distance, load or work. Examples provided here relate to the development of a new PES for the Canadian Armed Forces (CAF). SME of various experience are selected based on their eligibility criteria. SME are required to define a reasonable scenario for each task from personal experience, provide occupational performance requirements of the scenario in sub-groups, and discuss and agree by consensus vote on the final standard based on the definition of essential. A common and essential task for the CAF is detailed as a case example of process application. Techniques to avoid common SME rating errors are discussed and advantages to the method described. The SETS method was developed as a systematic approach to setting occupational performance standards and qualifying information from SME.

  8. The text of the Agreement establishing the Asian Regional Co-operative Project on Medical and Biological Applications of Nuclear Techniques

    International Nuclear Information System (INIS)

    1987-04-01

    The full text of the Agreement establishing the Asian Regional Co-operative Project on Medical and Biological Applications of Nuclear Techniques between the Agency and Member States is reproduced. The Agreement entered into force on 20 May 1986 after the Governments of Japan, Bangladesh and the Philippines had notified the Agency of their acceptance of the Agreement

  9. The urban density premium across establishments

    OpenAIRE

    R. Jason Faberman; Matthew Freedman

    2013-01-01

    We use longitudinal microdata to estimate the urban density premium for U.S. establishments, controlling for observed establishment characteristics and dynamic establishment behavior. Consistent with previous studies, we estimate a density premium between 6 and 10 percent, even after controlling for establishment composition, local skill mix, and the endogeneity of location choice. More importantly, we find that the estimated density premium is realized almost entirely at birth and is constan...

  10. [A brief history of resuscitation - the influence of previous experience on modern techniques and methods].

    Science.gov (United States)

    Kucmin, Tomasz; Płowaś-Goral, Małgorzata; Nogalski, Adam

    2015-02-01

    Cardiopulmonary resuscitation (CPR) is relatively novel branch of medical science, however first descriptions of mouth-to-mouth ventilation are to be found in the Bible and literature is full of descriptions of different resuscitation methods - from flagellation and ventilation with bellows through hanging the victims upside down and compressing the chest in order to stimulate ventilation to rectal fumigation with tobacco smoke. The modern history of CPR starts with Kouwenhoven et al. who in 1960 published a paper regarding heart massage through chest compressions. Shortly after that in 1961Peter Safar presented a paradigm promoting opening the airway, performing rescue breaths and chest compressions. First CPR guidelines were published in 1966. Since that time guidelines were modified and improved numerously by two leading world expert organizations ERC (European Resuscitation Council) and AHA (American Heart Association) and published in a new version every 5 years. Currently 2010 guidelines should be obliged. In this paper authors made an attempt to present history of development of resuscitation techniques and methods and assess the influence of previous lifesaving methods on nowadays technologies, equipment and guidelines which allow to help those women and men whose life is in danger due to sudden cardiac arrest. © 2015 MEDPRESS.

  11. Establishment, maintenance, and re-establishment of the safe and efficient steady-following state

    International Nuclear Information System (INIS)

    Pan Deng; Zheng Ying-Ping

    2015-01-01

    We present an integrated mathematical model of vehicle-following control for the establishment, maintenance, and re-establishment of the previous or new safe and efficient steady-following state. The hyperbolic functions are introduced to establish the corresponding mathematical models, which can describe the behavioral adjustment of the following vehicle steered by a well-experienced driver under complex vehicle following situations. According to the proposed mathematical models, the control laws of the following vehicle adjusting its own behavior can be calculated for its moving in safety, efficiency, and smoothness (comfort). Simulation results show that the safe and efficient steady-following state can be well established, maintained, and re-established by its own smooth (comfortable) behavioral adjustment with the synchronous control of the following vehicle’s velocity, acceleration, and the actual following distance. (paper)

  12. Differential zinc uptake of rice genotypes as established by radiotracer technique

    International Nuclear Information System (INIS)

    Sudhalakshmi, C.; Krishnasamy, R.; Meena, S.

    2017-01-01

    Rice is a sensitive crop to zinc (Zn 2+ ) deficiency and its uptake, transport and metabolism is imperative in bio-fortification process. A pot culture experiment was conducted at Tamil Nadu Agricultural University, Coimbatore to establish the differential zinc use efficiency of rice genotypes viz., Zn efficient Norungan and Zn inefficient PMK 3 and to assess the partitioning of Zn in shoot and root of genotypes employing radiotracer technique. Graded levels of Zn (0, 12.5, 25.0, 37.5 and 50 kg ha -1 of ZnSO 4 ) as 65 Zn labeled ZnSO 4 were applied. Zinc uptake from fertilizer increased with increased dose of applied zinc up to 37.5 kg ha -1 for PMK 3 whereas in Norungan, it was up to 25 kg ZnSO 4 ha -1 and thereafter it declined. The per cent zinc derived from fertilizer (% Zndff) was the highest in PMK 3 which apparently implies its inability to mobilize soil nutrient reserve and respond to elevated doses of applied zinc. The % Zndfs was higher in Norungan. In both the genotypes, the 'A value' showed a conspicuous increase with increased dose of applied zinc. Norungan registered a higher 'A value' than PMK 3 irrespective of the stages of sampling. Zn efficient Norungan had better Zn translocation to the shoots whereas in Zn inefficient PMK 3, vacuolar sequestration in root cells was higher. (author)

  13. Primary water stress corrosion cracks in nickel alloy dissimilar metal welds: Detection and sizing using established and emerging nondestructive examination techniques

    International Nuclear Information System (INIS)

    Braatz, B.G.; Doctor, S.R.; Cumblidge, S.E.; Prokofiev, I.G.

    2012-01-01

    The U.S. Nuclear Regulatory Commission has established the Program to Assess the Reliability of Emerging Nondestructive Techniques (PARENT) as a follow-on to the international cooperative Program for the Inspection of Nickel Alloy Components (PINC). The goal of PINC was to evaluate the capabilities of various nondestructive evaluation (NDE) techniques to detect and characterize surface-breaking primary water stress corrosion cracks in dissimilar-metal welds (DMW) in bottom-mounted instrumentation (BMI) penetrations and small-bore (∼400-mm diameter) piping components. A series of international blind round-robin tests were conducted by commercial and university inspection teams. Results from these tests showed that a combination of conventional and phased-array ultrasound techniques provided the highest performance for flaw detection and depth sizing in dissimilar metal piping welds. The effective detection of flaws in BMIs by eddy current and ultrasound shows that it may be possible to reliably inspect these components in the field. The goal of PARENT is to continue the work begun in PINC and apply the lessons learned to a series of open and blind international round-robin tests that will be conducted on a new set of piping components including large-bore (∼900-mm diameter) DMWs, small-bore DMWs, and BMIs. Open round-robin testing will engage universities and industry worldwide to investigate the reliability of emerging NDE techniques to detect and accurately size flaws having a wide range of lengths, depths, orientations, and locations. Blind round-robin testing will invite testing organizations worldwide, whose inspectors and procedures are certified by the standards for the nuclear industry in their respective countries, to investigate the ability of established NDE techniques to detect and size flaws whose characteristics range from easy to very difficult to detect and size. This paper presents highlights of PINC and reports on the plans and progress for

  14. Primary Water Stress Corrosion Cracks in Nickel Alloy Dissimilar Metal Welds: Detection and Sizing Using Established and Emerging Nondestructive Examination Techniques

    Energy Technology Data Exchange (ETDEWEB)

    Braatz, Brett G.; Cumblidge, Stephen E.; Doctor, Steven R.; Prokofiev, Iouri

    2012-12-31

    The U.S. Nuclear Regulatory Commission has established the Program to Assess the Reliability of Emerging Nondestructive Techniques (PARENT) as a follow-on to the international cooperative Program for the Inspection of Nickel Alloy Components (PINC). The goal of PINC was to evaluate the capabilities of various nondestructive evaluation (NDE) techniques to detect and characterize surface-breaking primary water stress corrosion cracks in dissimilar-metal welds (DMW) in bottom-mounted instrumentation (BMI) penetrations and small-bore (≈400-mm diameter) piping components. A series of international blind round-robin tests were conducted by commercial and university inspection teams. Results from these tests showed that a combination of conventional and phased-array ultrasound techniques provided the highest performance for flaw detection and depth sizing in dissimilar metal piping welds. The effective detection of flaws in BMIs by eddy current and ultrasound shows that it may be possible to reliably inspect these components in the field. The goal of PARENT is to continue the work begun in PINC and apply the lessons learned to a series of open and blind international round-robin tests that will be conducted on a new set of piping components including large-bore (≈900-mm diameter) DMWs, small-bore DMWs, and BMIs. Open round-robin testing will engage universities and industry worldwide to investigate the reliability of emerging NDE techniques to detect and accurately size flaws having a wide range of lengths, depths, orientations, and locations. Blind round-robin testing will invite testing organizations worldwide, whose inspectors and procedures are certified by the standards for the nuclear industry in their respective countries, to investigate the ability of established NDE techniques to detect and size flaws whose characteristics range from easy to very difficult to detect and size. This paper presents highlights of PINC and reports on the plans and progress for

  15. RETRACTED: Acute preoperative plasmapheresis and established blood conservation techniques.

    Science.gov (United States)

    Boldt, J; Kling, D; Zickmann, B; Jacobi, M; Dapper, F; Hempelmann, G

    1990-07-01

    Plasmapheresis performed weeks before an operation producing autologous plasma has proved to be of benefit in elective operations. First experiences in acute plasmapheresis, which is performed immediately before the operation, have been reported recently. When acute plasmapheresis is used in cardiac operations, however, it must be viewed in connection with other techniques for reducing blood consumption such as the Cell Saver (CS) and ultrafiltration devices. In 60 patients undergoing elective aortocoronary bypass grafting, acute plasmapheresis was performed, producing either platelet-poor plasma or platelet-rich plasma, in combination with either the Cell Saver or hemofiltration. Fluid balance during cardiopulmonary bypass was significantly lower in the hemofiltration patients. Postoperatively, none of these patients received donor blood, whereas 4 patients of the Cell-Saver groups needed packed red blood cells. AT-III, fibrinogen, the number of platelets, albumin, total protein, and colloid osmotic pressure were less compromised when hemofiltration was used in combination with acute plasmapheresis in contrast to combination with the Cell-Saver technique. Plasma hemoglobin was without differences during the investigation period, and polymorphonuclear elastase was less increased when platelet-rich plasma was produced preoperatively. On the first postoperative day, most of the differences between the groups had already disappeared. We conclude that when acute plasmapheresis is used in cardiac operations, discarding of plasma by the Cell Saver should be avoided and ultrafiltration devices should replace centrifugation techniques for blood conservation.

  16. [Estimating child mortality using the previous child technique, with data from health centers and household surveys: methodological aspects].

    Science.gov (United States)

    Aguirre, A; Hill, A G

    1988-01-01

    2 trials of the previous child or preceding birth technique in Bamako, Mali, and Lima, Peru, gave very promising results for measurement of infant and early child mortality using data on survivorship of the 2 most recent births. In the Peruvian study, another technique was tested in which each woman was asked about her last 3 births. The preceding birth technique described by Brass and Macrae has rapidly been adopted as a simple means of estimating recent trends in early childhood mortality. The questions formulated and the analysis of results are direct when the mothers are visited at the time of birth or soon after. Several technical aspects of the method believed to introduce unforeseen biases have now been studied and found to be relatively unimportant. But the problems arising when the data come from a nonrepresentative fraction of the total fertile-aged population have not been resolved. The analysis based on data from 5 maternity centers including 1 hospital in Bamako, Mali, indicated some practical problems and the information obtained showed the kinds of subtle biases that can result from the effects of selection. The study in Lima tested 2 abbreviated methods for obtaining recent early childhood mortality estimates in countries with deficient vital registration. The basic idea was that a few simple questions added to household surveys on immunization or diarrheal disease control for example could produce improved child mortality estimates. The mortality estimates in Peru were based on 2 distinct sources of information in the questionnaire. All women were asked their total number of live born children and the number still alive at the time of the interview. The proportion of deaths was converted into a measure of child survival using a life table. Then each woman was asked for a brief history of the 3 most recent live births. Dates of birth and death were noted in month and year of occurrence. The interviews took only slightly longer than the basic survey

  17. Investigation of previously derived Hyades, Coma, and M67 reddenings

    International Nuclear Information System (INIS)

    Taylor, B.J.

    1980-01-01

    New Hyades polarimetry and field star photometry have been obtained to check the Hyades reddening, which was found to be nonzero in a previous paper. The new Hyades polarimetry implies essentially zero reddening; this is also true of polarimetry published by Behr (which was incorrectly interpreted in the previous paper). Four photometric techniques which are presumed to be insensitive to blanketing are used to compare the Hyades to nearby field stars; these four techniques also yield essentially zero reddening. When all of these results are combined with others which the author has previously published and a simultaneous solution for the Hyades, Coma, and M67 reddenings is made, the results are E (B-V) =3 +- 2 (sigma) mmag, -1 +- 3 (sigma) mmag, and 46 +- 6 (sigma) mmag, respectively. No support for a nonzero Hyades reddening is offered by the new results. When the newly obtained reddenings for the Hyades, Coma, and M67 are compared with results from techniques given by Crawford and by users of the David Dunlap Observatory photometric system, no differences between the new and other reddenings are found which are larger than about 2 sigma. The author had previously found that the M67 main-sequence stars have about the same blanketing as that of Coma and less blanketing than the Hyades; this conclusion is essentially unchanged by the revised reddenings

  18. Changes in the dominance hierarchy of captive female Japanese macaques as a consequence of merging two previously established groups.

    Science.gov (United States)

    Anderson, Emily J; Weladji, Robert B; Paré, Patrick

    2016-11-01

    Dominance hierarchies play an important role in reducing competition and aggression in social animals. In zoos, changes in group composition are often required due to management protocols, but these changes may have long lasting effects on dominance hierarchies, and, consequently, the wellbeing of the animals. We studied the changes in the female dominance hierarchy that occurred both during and after the formation of a group of 10 adult Japanese macaques at the Zoo de Granby by combining members from two previously established groups. There was no significant correlation between individual ranks in the old groups (groups A and B) and their ranks in the new group (group AB), indicating a significant change in the hierarchy. Alliances between kin appeared to be important in determining rank; when the sister of the dominant female was removed from group AB, the hierarchy changed significantly a second time. The average standardized rank of individuals added later in the formation process of group AB was not different from those added earlier. Ranks in the group AB did correlate with age of individual at the beginning of the field season, but not at the end, after the shift in hierarchy occurred. Zoo management must be aware of the consequences small changes in a social group can have when removing and transferring individuals in both primates and in other social species. Zoo Biol. 35:505-512, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  19. Hepatitis B immunisation in persons not previously exposed to hepatitis B or with unknown exposure status

    DEFF Research Database (Denmark)

    Mathew, Joseph L; El Dib, Regina; Mathew, Preethy J

    2008-01-01

    The benefits and harms of hepatitis B vaccination in persons not previously exposed to hepatitis B infection or with unknown exposure status have not been established.......The benefits and harms of hepatitis B vaccination in persons not previously exposed to hepatitis B infection or with unknown exposure status have not been established....

  20. Life-history traits in an evergreen Mediterranean oak respond differentially to previous experimental environments

    Directory of Open Access Journals (Sweden)

    J. M. Rey Benayas

    2008-06-01

    Full Text Available Living organisms respond both to current and previous environments, which can have important consequences on population dynamics. However, there is little experimental evidence based on long-term field studies of the effects of previous environments on the performance of individuals. We tested the hypothesis that trees that establish under different environmental conditions perform differently under similar post-establishment conditions. We used the slow-growing, evergreen Mediterranean oak Quercus ilex subsp. rotundifolia as target species. We analyzed the effects of previous environments, competition effects and tradeoffs among life-history traits (survival, growth, and reproduction. We enhanced seedling establishment for three years by reducing abiotic environmental harshness by means of summer irrigation and artificial shading in 12 experimental plots, while four plots remained as controls. Then these treatments were interrupted for ten years. Seedlings under ameliorated environmental conditions survived and grew faster during early establishment. During the post-management period, previous treatments 1 did not have any effect on survival, 2 experienced a slower above-ground growth, 3 decreased root biomass as indicated from reflectivity of Ground Penetration Radar, 4 increased acorn production mostly through a greater canopy volume and 5 increased acorn production effort. The trees exhibited a combination of effects related to acclimation for coping with abiotic stress and effects of intra-specific competition. In accordance with our hypothesis, tree performance overall depended on previous environmental conditions, and the response was different for different life-history traits. We recommend early management because it increased plot cover, shortened the time to attain sexual maturity and increased the amount of acorn production. Plots such as those assessed in this study may act as sources of propagules in deforested

  1. Establishing molecular microbiology facilities in developing countries

    Directory of Open Access Journals (Sweden)

    Salman S. Ahmed

    2015-11-01

    Full Text Available Summary: Microbiology laboratories play an important role in epidemiology and infection control programs. Within microbiology laboratories, molecular microbiology techniques have revolutionized the identification and surveillance of infectious diseases. The combination of excellent sensitivity, specificity, low contamination levels and speed has made molecular techniques appealing methods for the diagnosis of many infectious diseases. In a well-equipped microbiology laboratory, the facility designated for molecular techniques remains indiscrete. However, in most developing countries, poor infrastructure and laboratory mismanagement have precipitated hazardous consequences. The establishment of a molecular microbiology facility within a microbiology laboratory remains fragmented. A high-quality laboratory should include both conventional microbiology methods and molecular microbiology techniques for exceptional performance. Furthermore, it should include appropriate laboratory administration, a well-designed facility, laboratory procedure standardization, a waste management system, a code of practice, equipment installation and laboratory personnel training. This manuscript lays out fundamental issues that need to be addressed when establishing a molecular microbiology facility in developing countries. Keywords: Developing country, Molecular technique, Molecular microbiology laboratory

  2. A hollow definitive obturator fabrication technique for management of partial maxillectomy.

    Science.gov (United States)

    Patil, Pravinkumar Gajanan; Patil, Smita Pravinkumar

    2012-11-01

    Maxillary obturator prosthesis is the most frequent treatment option for management of partial or total maxillectomy. Heavy weight of the obturators is often a dislocating factor. Hollowing the prosthesis to reduce its weight is the well established fact. The alternate technique to hollow-out the prosthesis has been described in this article which is a variation of previously described processing techniques. A pre-shaped wax-bolus was incorporated inside the flasks during packing of the heat-polymerized acrylic resin to automatically create the hollow space. The processing technique described is a single step flasking procedure to construct a closed-hollow-obturator prosthesis as a single unit. To best understand the technique, this article describes management of a patient who had undergone partial maxillectomy secondary to squamous cell carcinoma rehabilitated with a hollow-obturator prosthesis.

  3. Indications and technique of fetal magnetic resonance imaging; Indikationen und Technik der fetalen Magnetresonanztomographie

    Energy Technology Data Exchange (ETDEWEB)

    Asenbaum, U.; Woitek, R.; Furtner, J.; Prayer, D. [Medizinische Universitaet Wien, Abteilung fuer Neuroradiologie und Muskuloskelettale Radiologie, Universitaetsklinik fuer Radiodiagnostik, Wien (Austria); Brugger, P.C. [Medizinische Universitaet Wien, Zentrum fuer Anatomie und Zellbiologie, Wien (Austria)

    2013-02-15

    Evaluation and confirmation of fetal pathologies previously suspected or diagnosed with ultrasound. Ultrasound and magnetic resonance imaging (MRI). Technique for prenatal fetal examination. Fetal MRI is an established supplementary technique to prenatal ultrasound. Fetal MRI should only be used as an additional method in prenatal diagnostics and not for routine screening. Fetal MRI should only be performed in perinatal medicine centers after a previous level III ultrasound examination. (orig.) [German] Evaluierung und Bestaetigung von im praenatalen Ultraschall entdeckten Pathologien. Ultraschall und Magnetresonanztomographie. Praenatale Untersuchungsmethode. Die fetale MRT ist inzwischen als ergaenzende Methode zum praenatalen Ultraschall anerkannt. Die fetale MRT soll als additive Methode bei klinischer Relevanz, nicht jedoch als Routinescreeningverfahren waehrend der Schwangerschaft angewendet werden. Durchfuehrung ausschliesslich an einem Perinatalzentrum nach vorangegangenem Level-III-Ultraschall. (orig.)

  4. Evaluation of a titanium dioxide-based DGT technique for measuring inorganic uranium species in fresh and marine waters

    DEFF Research Database (Denmark)

    Hutchins, Colin M.; Panther, Jared G.; Teasdale, Peter R.

    2012-01-01

    A new diffusive gradients in a thin film (DGT) technique for measuring dissolved uranium (U) in freshwater is reported. The new method utilises a previously described binding phase, Metsorb (a titanium dioxide based adsorbent). This binding phase was evaluated and compared to the well-established...

  5. Development og groundwater flow modeling techniques for the low-level radwaste disposal (III)

    Energy Technology Data Exchange (ETDEWEB)

    Bae, Dae-Seok; Kim, Chun-Soo; Kim, Kyung-Soo; Park, Byung-Yoon; Koh, Yong-Kweon; Park, Hyun-Soo [Korea Atomic Energy Research Institute, Taejeon (Korea)

    2000-12-01

    The project amis to establish the methodology of hydrogeologic assessment by the field application of the evaluation techniques gained and accumulated from the previous hydrogeological research works in Korea. The results of the project and their possible areas for application are (1) acquisition of detailed hydrogeologic information by using a borehole televiewer and a multipacker system, (2) establishing an integrated hydrogeological assessment method for fractured rocks, (3) acquisition of the fracture parameters for fracture modeling, (4) an inversion analysis of hydraulic parameters from fracture network modeling, (5) geostatistical methods for the spatial assignment of hydraulic parameters for fractured rocks, and (6) establishing the groundwater flow modeling procedure for a repository. 75 refs., 72 figs., 34 tabs. (Author)

  6. Re-Operationalizing Established Groups in Brainstorming: Validating Osborn's Claims

    Science.gov (United States)

    Levine, Kenneth J.; Heuett, Kyle B.; Reno, Katie M.

    2017-01-01

    Since the introduction of brainstorming as an idea-generation technique to address organizational problems, researchers have struggled to replicate some of the claims around the technique. One major concern has been the differences in the number of ideas generated between established groups as found in industry versus the non-established groups…

  7. In vivo dosimetry for total body irradiation: five‐year results and technique comparison

    Science.gov (United States)

    Warry, Alison J.; Eaton, David J.; Collis, Christopher H.; Rosenberg, Ivan

    2014-01-01

    The aim of this work is to establish if the new CT‐based total body irradiation (TBI) planning techniques used at University College London Hospital (UCLH) and Royal Free Hospital (RFH) are comparable to the previous technique at the Middlesex Hospital (MXH) by analyzing predicted and measured diode results. TBI aims to deliver a homogeneous dose to the entire body, typically using extended SSD fields with beam modulation to limit doses to organs at risk. In vivo dosimetry is used to verify the accuracy of delivered doses. In 2005, when the Middlesex Hospital was decommissioned and merged with UCLH, both UCLH and the RFH introduced updated CT‐planned TBI techniques, based on the old MXH technique. More CT slices and in vivo measurement points were used by both; UCLH introduced a beam modulation technique using MLC segments, while RFH updated to a combination of lead compensators and bolus. Semiconductor diodes were used to measure entrance and exit doses in several anatomical locations along the entire body. Diode results from both centers for over five years of treatments were analyzed and compared to the previous MXH technique for accuracy and precision of delivered doses. The most stable location was the field center with standard deviations of 4.1% (MXH), 3.7% (UCLH), and 1.7% (RFH). The least stable position was the ankles. Mean variation with fraction number was within 1.5% for all three techniques. In vivo dosimetry can be used to verify complex modulated CT‐planned TBI, and demonstrate improvements and limitations in techniques. The results show that the new UCLH technique is no worse than the previous MXH one and comparable to the current RFH technique. PACS numbers: 87.55.Qr, 87.56.N‐ PMID:25207423

  8. Artificial intelligence techniques used in respiratory sound analysis--a systematic review.

    Science.gov (United States)

    Palaniappan, Rajkumar; Sundaraj, Kenneth; Sundaraj, Sebastian

    2014-02-01

    Artificial intelligence (AI) has recently been established as an alternative method to many conventional methods. The implementation of AI techniques for respiratory sound analysis can assist medical professionals in the diagnosis of lung pathologies. This article highlights the importance of AI techniques in the implementation of computer-based respiratory sound analysis. Articles on computer-based respiratory sound analysis using AI techniques were identified by searches conducted on various electronic resources, such as the IEEE, Springer, Elsevier, PubMed, and ACM digital library databases. Brief descriptions of the types of respiratory sounds and their respective characteristics are provided. We then analyzed each of the previous studies to determine the specific respiratory sounds/pathology analyzed, the number of subjects, the signal processing method used, the AI techniques used, and the performance of the AI technique used in the analysis of respiratory sounds. A detailed description of each of these studies is provided. In conclusion, this article provides recommendations for further advancements in respiratory sound analysis.

  9. Determination of sulfate in thorium salts using gravimetric technique with previous thorium separation

    International Nuclear Information System (INIS)

    Silva, C.M. da; Pires, M.A.F.

    1994-01-01

    Available as short communication only. A simple analytical method to analyze sulfates in thorium salt, is presented. The method is based on the thorium separation as hydroxide. The gravimetric technique is used to analyze the sulfate in the filtered as barium sulfate. Using this method, the sulfate separation from thorium has been reach 99,9% yield, and 0,1% precision. This method is applied to thorium salts specifically thorium sulfate, carbonate and nitrate. (author). 5 refs, 2 tabs

  10. A strategy for establishing diagnostic and related services to dairy farmers in developing countries based on radioimmunoassay of progesterone in milk

    International Nuclear Information System (INIS)

    Galloway, D.B.; Perera, B.M.A.O.; Manar, S.

    2001-01-01

    The radioimmunoassay (RIA) for progesterone in milk samples collected from cattle has been used for monitoring ovarian activity, diagnosis of pregnancy and non-pregnancy, assessment of the accuracy of oestrus detection and for surveying efficiency of artificial insemination services. The establishment of a service to dairy farmers in developing countries based on this technique has not been previously reported but there are clear potential benefits in such a service. A strategy was therefore developed for the establishment of diagnostic and related services to dairy farmers in Morocco on a pilot basis, using RIA of progesterone in milk for possible adoption as a model for other developing countries. (author)

  11. What Triggers the Establishment of a Works Council?

    OpenAIRE

    Jens Mohrenweiser; Paul Marginson; Uschi Backes-Gellner

    2009-01-01

    This paper analyses events that trigger the establishment of a works council and the actor or agent who triggers it. The paper extends previous research in two dimensions. First, we examine specific events that motivate workers to establish a works council, such as a change of owner, founding a spin-off, a firm-acquisition or a radical restructuring. These events express risk protection as workers’ primary motivation for establishing a works council. Second, we analyse the actor or agent who ...

  12. Water retention techniques for vegetation establishment in TxDOT West Texas districts.

    Science.gov (United States)

    2010-03-01

    Water harvesting is the collection of runoff for its productive use and may aid in the germination and : establishment of vegetation seeded in the roadside. This project is a synthesis study on the feasibility and : implications of adapting water har...

  13. Development of hotcell non-destructive examination techniques

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Young Uhn; Yu, S. C.; Kang, B. S.; Byun, K. S. [Chungbuk National University, Chungju (Korea)

    2002-01-01

    The purpose of this project is to establish non-destructive examination techniques which needs to determine the status of spent nuclear fuel and/or bundles. Through the project, we will establish an image reconstruction tomography which is a kind of non-destructive techniques in Hotcell. The tomography technique can be used to identify the 2-dimensional density distribution of fission products in the spent fuel rods and/or bundles. And form results of the measurement and analysis of magnetic properties of neutron irradiated material in the press vessel and reactor, we will develop some techniques to test its hardness and defects. In 2001, the first year, we have established mathematical background and necessary data and informations to develop the techniques. We will try to find some experimental results that are necessary in developing the Hotcell non-destructive examination techniques in the coming year. 14 refs., 65 figs., 5 tabs. (Author)

  14. Establishing a Multi-scale Stream Gaging Network in the Whitewater River Basin, Kansas, USA

    Science.gov (United States)

    Clayton, J.A.; Kean, J.W.

    2010-01-01

    Investigating the routing of streamflow through a large drainage basin requires the determination of discharge at numerous locations in the channel network. Establishing a dense network of stream gages using conventional methods is both cost-prohibitive and functionally impractical for many research projects. We employ herein a previously tested, fluid-mechanically based model for generating rating curves to establish a stream gaging network in the Whitewater River basin in south-central Kansas. The model was developed for the type of channels typically found in this watershed, meaning that it is designed to handle deep, narrow geomorphically stable channels with irregular planforms, and can model overbank flow over a vegetated floodplain. We applied the model to ten previously ungaged stream reaches in the basin, ranging from third- to sixth-order channels. At each site, detailed field measurements of the channel and floodplain morphology, bed and bank roughness, and vegetation characteristics were used to quantify the roughness for a range of flow stages, from low flow to overbank flooding. Rating curves that relate stage to discharge were developed for all ten sites. Both fieldwork and modeling were completed in less than 2 years during an anomalously dry period in the region, which underscores an advantage of using theoretically based (as opposed to empirically based) discharge estimation techniques. ?? 2010 Springer Science+Business Media B.V.

  15. Method for efficient establishment of technical biodosimetry competence

    International Nuclear Information System (INIS)

    Stricklin, D.; Jaworska, Alicja; Arvidsson, E.

    2007-01-01

    The current gold standard in biodosimetry, the dicentric assay, requires documented technical competence. Expertise is developed over time by evaluation of thousands of metaphases. Competence is documented through establishment of a dose-response curve, required by any service laboratory performing biodosimetry. Consistent and reliable evaluations must be established for new observers that might contribute to analyses for biological dose assessments. Discrepancies in evaluations jeopardize the reliability of assessments. The Swedish Defence Research Agency (FOI) together with the Norwegian Radiation Protection Authority (NRPA) conducted an inter-calibration exercise for the purpose of establishing comparable scoring criteria for evaluation of aberrations in metaphases. The exercise revealed specific aberrations that were difficult to identify and were consistent sources of uncertainty. Subsequently, a report detailing the FOI's scoring criteria was developed with visual examples and a strategy for establishing technical competence in metaphase scoring in an efficient manner evolved. Key components of the strategy are the review of guidance for biodosimetry, performance of inter-calibration exercises with previously established data sets, review of incongruous evaluations with a well-established observer, follow-up exercises depending on the initial outcome, and inter-comparisons to document agreement. Methods suggested here could be applied in training of new personnel. Documentation of methods in other laboratories could facilitate more consistent scoring criteria among the biodosimetry community, a problem observed in previous international inter-comparisons. Improved consistency among biodosimetry laboratories could facilitate reliably sharing the work load among different members of the biodosimetry community in the event of a mass casualty accident

  16. Optimal technique of linear accelerator-based stereotactic radiosurgery for tumors adjacent to brainstem.

    Science.gov (United States)

    Chang, Chiou-Shiung; Hwang, Jing-Min; Tai, Po-An; Chang, You-Kang; Wang, Yu-Nong; Shih, Rompin; Chuang, Keh-Shih

    2016-01-01

    Stereotactic radiosurgery (SRS) is a well-established technique that is replacing whole-brain irradiation in the treatment of intracranial lesions, which leads to better preservation of brain functions, and therefore a better quality of life for the patient. There are several available forms of linear accelerator (LINAC)-based SRS, and the goal of the present study is to identify which of these techniques is best (as evaluated by dosimetric outcomes statistically) when the target is located adjacent to brainstem. We collected the records of 17 patients with lesions close to the brainstem who had previously been treated with single-fraction radiosurgery. In all, 5 different lesion catalogs were collected, and the patients were divided into 2 distance groups-1 consisting of 7 patients with a target-to-brainstem distance of less than 0.5cm, and the other of 10 patients with a target-to-brainstem distance of ≥ 0.5 and linear accelerator is only 1 modality can to establish for SRS treatment. Based on statistical evidence retrospectively, we recommend VMAT as the optimal technique for delivering treatment to tumors adjacent to brainstem. Copyright © 2016 American Association of Medical Dosimetrists. All rights reserved.

  17. The development and use of decision aiding techniques for establishing intervention levels

    International Nuclear Information System (INIS)

    Kelly, G.N.; Sinnaeve, J.

    1989-01-01

    Following the Chernobyl accident there has been considerable international discussion on the principles underlying the choice of intervention levels and their practical application. While there is broad agreement on the underlying principles - that is to put potentially exposed individuals into a better position in the sense that lower overall risks are achieved at reasonable cost in financial and social terms - the determination of what constitutes the most appropriate type and level of intervention in any particular circumstances is more complex. Within the CEC Radiation Protection Research Programme techniques are being developed to aid well founded and more transparent decisions on the choice of intervention levels. The techniques are described and areas identified where they might usefully be applied

  18. [Study on standardization of cupping technique: elucidation on the establishment of the National Standard Standardized Manipulation of Acupuncture and Moxibustion, Part V, Cupping].

    Science.gov (United States)

    Gao, Shu-zhong; Liu, Bing

    2010-02-01

    From the aspects of basis, technique descriptions, core contents, problems and solutions, and standard thinking in standard setting process, this paper states experiences in the establishment of the national standard Standardized Manipulation of Acupuncture and Moxibustion, Part V, Cupping, focusing on methodologies used in cupping standard setting process, the method selection and operating instructions of cupping standardization, and the characteristics of standard TCM. In addition, this paper states the scope of application, and precautions for this cupping standardization. This paper also explaines tentative ideas on the research of standardized manipulation of acupuncture and moxibustion.

  19. Insulin resistance is not conserved in myotubes established from women with PCOS.

    Directory of Open Access Journals (Sweden)

    Mette Eriksen

    2010-12-01

    Full Text Available Polycystic ovary syndrome (PCOS is the most common endocrine disorder among premenopausal women, who often develop insulin resistance. We tested the hypothesis that insulin resistance in skeletal muscle of patients with polycystic ovary syndrome (PCOS is an intrinsic defect, by investigating the metabolic characteristics and gene expression of in vitro differentiated myotubes established from well characterized PCOS subjects.Using radiotracer techniques, RT-PCR and enzyme kinetic analysis we examined myotubes established from PCOS subjects with or without pioglitazone treatment, versus healthy control subjects who had been extensively metabolically characterized in vivo. Results. Myotubes established from PCOS and matched control subjects comprehensively expressed all insulin-sensitive biomarkers; glucose uptake and oxidation, glycogen synthesis and lipid uptake. There were no significant differences between groups either at baseline or during acute insulin stimulation, although in vivo skeletal muscle was insulin resistant. In particular, we found no evidence for defects in insulin-stimulated glycogen synthase activity between groups. Myotubes established from PCOS patients with or without pioglitazone treatment also showed no significant differences between groups, neither at baseline nor during acute insulin stimulation, although in vivo pioglitazone treatment significantly improved insulin sensitivity. Consistently, the myotube cultures failed to show differences in mRNA levels of genes previously demonstrated to differ in PCOS patients with or without pioglitazone treatment (PLEK, SLC22A16, and TTBK.These results suggest that the mechanisms governing insulin resistance in skeletal muscle of PCOS patients in vivo are not primary, but rather adaptive.ClinicalTrials.gov NCT00145340.

  20. An automated patient recognition method based on an image-matching technique using previous chest radiographs in the picture archiving and communication system environment

    International Nuclear Information System (INIS)

    Morishita, Junji; Katsuragawa, Shigehiko; Kondo, Keisuke; Doi, Kunio

    2001-01-01

    An automated patient recognition method for correcting 'wrong' chest radiographs being stored in a picture archiving and communication system (PACS) environment has been developed. The method is based on an image-matching technique that uses previous chest radiographs. For identification of a 'wrong' patient, the correlation value was determined for a previous image of a patient and a new, current image of the presumed corresponding patient. The current image was shifted horizontally and vertically and rotated, so that we could determine the best match between the two images. The results indicated that the correlation values between the current and previous images for the same, 'correct' patients were generally greater than those for different, 'wrong' patients. Although the two histograms for the same patient and for different patients overlapped at correlation values greater than 0.80, most parts of the histograms were separated. The correlation value was compared with a threshold value that was determined based on an analysis of the histograms of correlation values obtained for the same patient and for different patients. If the current image is considered potentially to belong to a 'wrong' patient, then a warning sign with the probability for a 'wrong' patient is provided to alert radiology personnel. Our results indicate that at least half of the 'wrong' images in our database can be identified correctly with the method described in this study. The overall performance in terms of a receiver operating characteristic curve showed a high performance of the system. The results also indicate that some readings of 'wrong' images for a given patient in the PACS environment can be prevented by use of the method we developed. Therefore an automated warning system for patient recognition would be useful in correcting 'wrong' images being stored in the PACS environment

  1. Application of multivariate techniques to analytical data on Aegean ceramics

    International Nuclear Information System (INIS)

    Bieber, A.M.; Brooks, D.W.; Harbottle, G.; Sayre, E.V.

    1976-01-01

    The general problems of data collection and handling for multivariate elemental analyses of ancient pottery are considered including such specific questions as the level of analytical precision required, the number and type of elements to be determined and the need for comprehensive multivariate statistical analysis of the collected data in contrast to element by element statistical analysis. The multivariate statistical procedures of clustering in a multidimensional space and determination of the numerical probabilities of specimens belonging to a group through calculation of the Mahalanobis distances for these specimens in multicomponent space are described together with supporting univariate statistical procedures used at Brookhaven. The application of these techniques to the data on Late Bronze Age Aegean pottery (largely previously analysed at Oxford and Brookhaven with some new specimens considered) have resulted in meaningful subdivisions of previously established groups. (author)

  2. Mississippi River streamflow measurement techniques at St. Louis, Missouri

    Science.gov (United States)

    Wastson, Chester C.; Holmes, Robert R.; Biedenham, David S.

    2013-01-01

    Streamflow measurement techniques of the Mississippi River at St. Louis have changed through time (1866–present). In addition to different methods used for discrete streamflow measurements, the density and range of discrete measurements used to define the rating curve (stage versus streamflow) have also changed. Several authors have utilized published water surface elevation (stage) and streamflow data to assess changes in the rating curve, which may be attributed to be caused by flood control and/or navigation structures. The purpose of this paper is to provide a thorough review of the available flow measurement data and techniques and to assess how a strict awareness of the limitations of the data may affect previous analyses. It is concluded that the pre-1930s discrete streamflow measurement data are not of sufficient accuracy to be compared with modern streamflow values in establishing long-term trends of river behavior.

  3. Prevalent musculoskeletal pain as a correlate of previous exposure to torture

    DEFF Research Database (Denmark)

    Olsen, Dorte Reff; Montgomery, Edith; Bojholm, S

    2006-01-01

    AIM: To research possible associations between previous exposure to specific torture techniques and prevalent pain in the head and face, back, and feet. METHODS: 221 refugees, 193 males and 28 females, previously exposed to torture in their home country, were subject to a clinical interview...... was general abuse of the whole body (OR 5.64, 95% CI 1.93-16.45). CONCLUSION: In spite of many factors being potentially co-responsible for prevalent pain, years after the torture took place it presents itself as strongly associated with specific loci of pain, with generalized effects, and with somatizing....

  4. Evolving techniques of diagnosis. Toward establishment of new paradigm for human machine cooperation

    International Nuclear Information System (INIS)

    Kitamura, Masaharu; Takahashi, Makoto; Kanamoto, Shigeru; Saeki, Akira; Washio, Takashi; Ohga, Yukiharu; Furuta, Kazuo; Yoshikawa, Shinji

    1998-01-01

    By monitoring equipments of a plant and state of a process, the diagnostic technique to detect a sign of abnormality properly to identify its reason has often been advanced on a lot of researches in various industrial fields containing atomic force. Some fundamental studies expected for such diagnostic technique to play an important role to keep and improve operational safety of a nuclear plant have been conducted since early period of the nuclear reaction development, but their contents are evolved and changed rapidly, in recent. The technique on the diagnosis was related closely to a statistical analysis method on signal fluctuation component, so-called reactor noise analysis method in early 1980s, but technical innovation step of their recent advancement were remarkable by introduction of new techniques such as chaos theory, wavelet analysis, model base application of expert system, artificial intelligence, and so on at middle of 1980s. And, when diagnosing in the field of atomic force, owing to be required for much high ability, studies on a multi method integration system considered complementary application of a plurality of technical methods and a cooperative method between human and mechanical intelligences, are also forwarded actively faster than those in other industrial areas. In this paper, in each important item, its technical nature and present state of its application to diagnosis are described with their future technical view. (G.K.)

  5. Fish quality – linking previous infections to the quality of consumers’ fillet

    DEFF Research Database (Denmark)

    The quality of the fish meat is dependent upon a wide range of biological and non-biological factors. In the present study it has been established that previous infections by Vibrio anguillarum in rainbow trout (Oncorhynchus mykiss) influence the quality of the fish meat (fillet) at slaughter more...... than after the fish have recovered from the infection. The texture of the fillet analysed by sensory analysis showed changes, which could be explained by previous tissue damage caused by the infection. These changes indicated formation of scars in affected tissue during the processes of tissue repair......, which gave rise to a more fibrous, tougher and flaky texture of the fillets....

  6. Previously unknown species of Aspergillus.

    Science.gov (United States)

    Gautier, M; Normand, A-C; Ranque, S

    2016-08-01

    The use of multi-locus DNA sequence analysis has led to the description of previously unknown 'cryptic' Aspergillus species, whereas classical morphology-based identification of Aspergillus remains limited to the section or species-complex level. The current literature highlights two main features concerning these 'cryptic' Aspergillus species. First, the prevalence of such species in clinical samples is relatively high compared with emergent filamentous fungal taxa such as Mucorales, Scedosporium or Fusarium. Second, it is clearly important to identify these species in the clinical laboratory because of the high frequency of antifungal drug-resistant isolates of such Aspergillus species. Matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) has recently been shown to enable the identification of filamentous fungi with an accuracy similar to that of DNA sequence-based methods. As MALDI-TOF MS is well suited to the routine clinical laboratory workflow, it facilitates the identification of these 'cryptic' Aspergillus species at the routine mycology bench. The rapid establishment of enhanced filamentous fungi identification facilities will lead to a better understanding of the epidemiology and clinical importance of these emerging Aspergillus species. Based on routine MALDI-TOF MS-based identification results, we provide original insights into the key interpretation issues of a positive Aspergillus culture from a clinical sample. Which ubiquitous species that are frequently isolated from air samples are rarely involved in human invasive disease? Can both the species and the type of biological sample indicate Aspergillus carriage, colonization or infection in a patient? Highly accurate routine filamentous fungi identification is central to enhance the understanding of these previously unknown Aspergillus species, with a vital impact on further improved patient care. Copyright © 2016 European Society of Clinical Microbiology and

  7. Developing isotope techniques for water exploration in the Sahel

    International Nuclear Information System (INIS)

    Aranyossy, J.F.; Louvat, D.; Maksoudi, M.

    1991-01-01

    The IAEA in the early 1980s started its first activities on hydrogeology in Mali, Niger, and Senegal through its technical co-operation programme. These activities included, first of all, local aquifer studies with environmental isotopes. The studies were found to be particularly useful for obtaining specific information on, for example, relationships between aquifers and between surface water and groundwater, and the existence or absence of recent recharge. Moreover, the IAEA established the basic infrastructures needed for the application of artificial tracer techniques and the use of nuclear instrumentation in hydrology and hydrosedimentology. Several factors underscored the need for co-ordinating the scientific activities already being carried out under existing bilateral projects. Firstly, the ''horizontal'' flow of information was very poor in spite of the similarity between the hydrological and hydrogeological problems encountered in the three countries. Secondly, political frontiers do not generally follow the boundaries of the hydrological basins, so that the same aquifer can be shared between several countries. Thirdly, the costly infrastructure established by the IAEA in certain countries deserved to be utilized at the regional level. To meet these concerns, an African regional project was launched 4 years ago on the development of isotope and nuclear techniques in hydrology in the Sahelian countries. Its main objectives were to further broaden ongoing studies in the participating countries; to strengthen training; to promote exchange of information on various previous studies; to foster co-operation between the different institutes involved in these studies; and to reinforce the infrastructures established by the IAEA and their utilization in the region

  8. Establishment probability in newly founded populations

    Directory of Open Access Journals (Sweden)

    Gusset Markus

    2012-06-01

    Full Text Available Abstract Background Establishment success in newly founded populations relies on reaching the established phase, which is defined by characteristic fluctuations of the population’s state variables. Stochastic population models can be used to quantify the establishment probability of newly founded populations; however, so far no simple but robust method for doing so existed. To determine a critical initial number of individuals that need to be released to reach the established phase, we used a novel application of the “Wissel plot”, where –ln(1 – P0(t is plotted against time t. This plot is based on the equation P0t=1–c1e–ω1t, which relates the probability of extinction by time t, P0(t, to two constants: c1 describes the probability of a newly founded population to reach the established phase, whereas ω1 describes the population’s probability of extinction per short time interval once established. Results For illustration, we applied the method to a previously developed stochastic population model of the endangered African wild dog (Lycaon pictus. A newly founded population reaches the established phase if the intercept of the (extrapolated linear parts of the “Wissel plot” with the y-axis, which is –ln(c1, is negative. For wild dogs in our model, this is the case if a critical initial number of four packs, consisting of eight individuals each, are released. Conclusions The method we present to quantify the establishment probability of newly founded populations is generic and inferences thus are transferable to other systems across the field of conservation biology. In contrast to other methods, our approach disaggregates the components of a population’s viability by distinguishing establishment from persistence.

  9. Plant-Damage Assessment Technique for Evaluating Military Vehicular Impacts to Vegetation in the Mojave Desert; TOPICAL

    International Nuclear Information System (INIS)

    D. J. Hansen; W. K. Ostler

    2001-01-01

    A new plant damage assessment technique was developed by plant ecologists from Bechtel Nevada at the U.S. Department of Energy's National Security Administration Nevada Operations Office and funded by the Strategic Environmental Research and Development Program Project CS-1131 in cooperation with the U.S. Army's National Training Center (NTC) at Fort Irwin, California. The technique establishes linear transects the width of vehicle tracts from evidence of vehicle tracks in the soil (usually during a prior training rotation period of 30 days or since the last rain or wind storm), and measures vegetation within the tracks to determine the area of plant parts being run over, the percent of the impacted parts damaged, and the percent of impacted parts expected to recover. It documents prior-damage classes based on estimated of damage that plants have apparently experienced previously (as assessed from field indicators of damage such as plant shape and height). The technique was used to evaluate different vehicle types (rubber-tire wheels vs. tracks) in six area at the NTC with different soils and training intensity levels. The technique provides tabular data that can be sorted and queried to show a variety of trends related to military vehicular impacts. The technique also appears suitable for assessing other non-military off-road traffic impacts. Findings report: (1) differences in plant sensitivity of different vehicular impacts, (2) plant cover and density by species and training area, (3) the degree to which wheels have less impact than tracks, and (4) the mean percent survival is inversely proportional to the degree of prior damage received by the vegetation (i.e., plants previously impacted have lower survival than plants not previously impacted)

  10. ESTABLISHMENT TECHNIQUES FOR TROPICAL LEGUMES IN THE UNDERSTORY OF A EUCALYPTUS PLANTATION

    Directory of Open Access Journals (Sweden)

    Maria Luiza Franceschi Nicodemo

    2015-04-01

    Full Text Available This study evaluated establishment methods for a mixture of herbaceous forage legumes [Centrosema acutifolium, Clitoria ternatea, Pueraria phaseoloides, Stylosanthes Campo Grande (Stylosanthes capitata + S. macrocephala, Calopogonium mucunoides, Lablab purpureus, Arachis pintoi, and Aeschynomene villosa] under the shade of an Eucalyptus grandis plantation submitted to thinning (40% 8 years after planting in Anhembi, São Paulo (22°40'S, 48°10'W, altitude of 455 m. The experiment started in December 2008 and consisted of the comparison of the following four types of seed incorporation by light disc harrowing: (1 broadcast sowing without seed incorporation; disc harrowing before (2 or after (3 planting, and (4 disc harrowing before and after planting. Ninety days after planting, the number of legume plants/m2 and the percentage of ground cover by the plants varied between the treatments tested; however, the treatments had no effect on the dry matter accumulation of forage legumes. Disc harrowing before planting yielded superior results compared to the treatments without disc harrowing and disc harrowing after planting. At the end of the experimental period, the plots contained Arachis, Centrosema, Stylosanthes, and Pueraria. The dry matter accumulated by Centrosema corresponded to 73% of total dry matter yield of the plots. The participation of Arachis, Centrosema and Stylosanthes in final dry matter composition of the plots varied according to establishment method. The advantages of the use of species mixtures rather than monocultures in the understory of forest plantations were discussed.

  11. Automated Techniques for the Qualitative Analysis of Ecological Models: Continuous Models

    Directory of Open Access Journals (Sweden)

    Lynn van Coller

    1997-06-01

    Full Text Available The mathematics required for a detailed analysis of the behavior of a model can be formidable. In this paper, I demonstrate how various computer packages can aid qualitative analyses by implementing techniques from dynamical systems theory. Because computer software is used to obtain the results, the techniques can be used by nonmathematicians as well as mathematicians. In-depth analyses of complicated models that were previously very difficult to study can now be done. Because the paper is intended as an introduction to applying the techniques to ecological models, I have included an appendix describing some of the ideas and terminology. A second appendix shows how the techniques can be applied to a fairly simple predator-prey model and establishes the reliability of the computer software. The main body of the paper discusses a ratio-dependent model. The new techniques highlight some limitations of isocline analyses in this three-dimensional setting and show that the model is structurally unstable. Another appendix describes a larger model of a sheep-pasture-hyrax-lynx system. Dynamical systems techniques are compared with a traditional sensitivity analysis and are found to give more information. As a result, an incomplete relationship in the model is highlighted. I also discuss the resilience of these models to both parameter and population perturbations.

  12. Intelligence, previous convictions and interrogative suggestibility: a path analysis of alleged false-confession cases.

    Science.gov (United States)

    Sharrock, R; Gudjonsson, G H

    1993-05-01

    The main purpose of this study was to investigate the relationship between interrogative suggestibility and previous convictions among 108 defendants in criminal trials, using a path analysis technique. It was hypothesized that previous convictions, which may provide defendants with interrogative experiences, would correlate negatively with 'shift' as measured by the Gudjonsson Suggestibility Scale (Gudjonsson, 1984a), after intelligence and memory had been controlled for. The hypothesis was partially confirmed and the theoretical and practical implications of the findings are discussed.

  13. Overview on Environmental Comprehensive Management System Established in Imitation of Biome

    Institute of Scientific and Technical Information of China (English)

    李如燕; 孙可伟

    2004-01-01

    Environmental comprehensive management system, called "the bionic community", can be established in imitation of biome, which can transform the wastes generated in a certain field into the raw materials of other field. The establishment of the bionic community includes two aspects, i.e. , the matching technique and the management system. The main matching technique is the preparation of composite materials made of various wastes.This new kind of material can be divided into four types: polymer matrix, silicate matrix, metal matrix and carbon matrix (or ceramic matrix). The environmental comprehensive management system is formed by organizing a transtrades joint-management business entity with the products of composite material made of wastes at the core.

  14. A robust trust establishment scheme for wireless sensor networks.

    Science.gov (United States)

    Ishmanov, Farruh; Kim, Sung Won; Nam, Seung Yeob

    2015-03-23

    Security techniques like cryptography and authentication can fail to protect a network once a node is compromised. Hence, trust establishment continuously monitors and evaluates node behavior to detect malicious and compromised nodes. However, just like other security schemes, trust establishment is also vulnerable to attack. Moreover, malicious nodes might misbehave intelligently to trick trust establishment schemes. Unfortunately, attack-resistance and robustness issues with trust establishment schemes have not received much attention from the research community. Considering the vulnerability of trust establishment to different attacks and the unique features of sensor nodes in wireless sensor networks, we propose a lightweight and robust trust establishment scheme. The proposed trust scheme is lightweight thanks to a simple trust estimation method. The comprehensiveness and flexibility of the proposed trust estimation scheme make it robust against different types of attack and misbehavior. Performance evaluation under different types of misbehavior and on-off attacks shows that the detection rate of the proposed trust mechanism is higher and more stable compared to other trust mechanisms.

  15. A Robust Trust Establishment Scheme for Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Farruh Ishmanov

    2015-03-01

    Full Text Available Security techniques like cryptography and authentication can fail to protect a network once a node is compromised. Hence, trust establishment continuously monitors and evaluates node behavior to detect malicious and compromised nodes. However, just like other security schemes, trust establishment is also vulnerable to attack. Moreover, malicious nodes might misbehave intelligently to trick trust establishment schemes. Unfortunately, attack-resistance and robustness issues with trust establishment schemes have not received much attention from the research community. Considering the vulnerability of trust establishment to different attacks and the unique features of sensor nodes in wireless sensor networks, we propose a lightweight and robust trust establishment scheme. The proposed trust scheme is lightweight thanks to a simple trust estimation method. The comprehensiveness and flexibility of the proposed trust estimation scheme make it robust against different types of attack and misbehavior. Performance evaluation under different types of misbehavior and on-off attacks shows that the detection rate of the proposed trust mechanism is higher and more stable compared to other trust mechanisms.

  16. Prevalence, distribution, and diversity of Listeria monocytogenes in retail environments, focusing on small establishments and establishments with a history of failed inspections.

    Science.gov (United States)

    Hoelzer, Karin; Sauders, Brian D; Sanchez, Maria D; Olsen, Peter T; Pickett, Michele M; Mangione, Kurt J; Rice, Daniel H; Corby, Joe; Stich, Stephen; Fortes, Esther D; Roof, Sherry E; Grohn, Yrjo T; Wiedmann, Martin; Oliver, Haley F

    2011-07-01

    Despite growing concerns about cross-contamination of ready-to-eat foods with Listeria monocytogenes, our knowledge about the ecology and transmission of L. monocytogenes in retail establishments has remained limited. We conducted a cross-sectional study to characterize the prevalence, distribution, and subtype diversity of L. monocytogenes in 120 New York State retail deli establishments that were hypothesized to present an increased risk for environmental L. monocytogenes contamination (i.e., small establishments and establishments with a history of failed New York State Agriculture and Markets inspections). Analysis of these data along with previously reported data for 121 predominantly larger retail establishments in New York State identified establishment size, geographic location, and inspection history as significant predictors of L. monocytogenes presence and prevalence. The odds of an establishment being L. monocytogenes positive were approximately twice as high for large establishments, establishments located in New York City, or establishments with poor inspection history (as compared with establishments without these attributes), even though correlation between location and inspection history complicated interpretation of results. Within an establishment, L. monocytogenes was significantly more prevalent on nonfood contact surfaces than on food contact surfaces; prevalence was particularly high for floors and in floor drains, sinks, the dairy case, and milk crates. L. monocytogenes subtype diversity differed between sites, with lineage I isolates significantly associated with nonfood contact surfaces and lineage II isolates significantly associated with food contact surfaces. Isolates belonging to the same ribotype were often found dispersed across multiple sites within an operation. Copyright ©, International Association for Food Protection

  17. Books average previous decade of economic misery.

    Science.gov (United States)

    Bentley, R Alexander; Acerbi, Alberto; Ormerod, Paul; Lampos, Vasileios

    2014-01-01

    For the 20(th) century since the Depression, we find a strong correlation between a 'literary misery index' derived from English language books and a moving average of the previous decade of the annual U.S. economic misery index, which is the sum of inflation and unemployment rates. We find a peak in the goodness of fit at 11 years for the moving average. The fit between the two misery indices holds when using different techniques to measure the literary misery index, and this fit is significantly better than other possible correlations with different emotion indices. To check the robustness of the results, we also analysed books written in German language and obtained very similar correlations with the German economic misery index. The results suggest that millions of books published every year average the authors' shared economic experiences over the past decade.

  18. Previous Mental Disorders and Subsequent Onset of Chronic Back or Neck Pain : Findings From 19 Countries

    NARCIS (Netherlands)

    Viana, Maria Carmen; Lim, Carmen C W; Garcia Pereira, Flavia; Aguilar-Gaxiola, Sergio; Alonso, Jordi; Bruffaerts, Ronny; de Jonge, Peter; Caldas-de-Almeida, Jose Miguel; O'Neill, Siobhan; Stein, Dan J; Al-Hamzawi, Ali; Benjet, Corina; Cardoso, Graça; Florescu, Silvia; de Girolamo, Giovanni; Haro, Josep Maria; Hu, Chiyi; Kovess-Masfety, Viviane; Levinson, Daphna; Piazza, Marina; Posada-Villa, José; Rabczenko, Daniel; Kessler, Ronald C; Scott, Kate M

    Associations between depression/anxiety and pain are well established, but its directionality is not clear. We examined the associations between temporally previous mental disorders and subsequent self-reported chronic back/neck pain onset, and investigated the variation in the strength of

  19. Development of an evaluation technique for human-machine interface

    Energy Technology Data Exchange (ETDEWEB)

    Min, Dae Hwan; Koo, Sang Hui; Ahn, Won Yeong; Ryu, Yeong Shin [Korea Univ., Seoul (Korea, Republic of)

    1997-07-15

    The purpose of this study is two-fold : firstly to establish an evaluation technique for HMI(Human Machine Interface) in NPPs(Nuclear Power Plants) and secondly to develop an architecture of a support system which can be used for the evaluation of HMI. In order to establish an evaluation technique, this study conducted literature review on basic theories of cognitive science studies and summarized the cognitive characteristics of humans. This study also surveyed evaluation techniques of HMI in general, and reviewed studies on the evaluation of HMI in NPPs. On the basis of this survey, the study established a procedure for the evaluation of HMI in NPPs in Korea and laid a foundation for empirical verification.

  20. Development of an evaluation technique for human-machine interface

    International Nuclear Information System (INIS)

    Min, Dae Hwan; Koo, Sang Hui; Ahn, Won Yeong; Ryu, Yeong Shin

    1997-07-01

    The purpose of this study is two-fold : firstly to establish an evaluation technique for HMI(Human Machine Interface) in NPPs(Nuclear Power Plants) and secondly to develop an architecture of a support system which can be used for the evaluation of HMI. In order to establish an evaluation technique, this study conducted literature review on basic theories of cognitive science studies and summarized the cognitive characteristics of humans. This study also surveyed evaluation techniques of HMI in general, and reviewed studies on the evaluation of HMI in NPPs. On the basis of this survey, the study established a procedure for the evaluation of HMI in NPPs in Korea and laid a foundation for empirical verification

  1. Hlaallele Detection Using Molecular Techniques

    Directory of Open Access Journals (Sweden)

    Philip A. Dyer

    1993-01-01

    Full Text Available There are now many molecular biological techniques available to define HLA class I and class II alleles. Some of these are also applicable to other human polymorphic genes, in particular to those non-HLA genes encoded within the Mhc. The range of techniques available allows laboratories to choose those most suited to their purpose. The routine laboratory supporting solid organ transplants will need to type large numbers of potential recipients over a period of time, probably using PCR-SSOP while donors will be typed singly and rapidly using PCR-SSP with HLA allele compatibility determined by heteroduplex analysis. Laboratories supporting bone marrow transplantation, where time is less pressing, can choose from the whole range of techniques to determine accurately donor recipient Mhc compatibility. For disease studies, techniques defining precise HLA allele sequence polymorphisms are needed and high sample numbers have to be accommodated. When an association is established allele sequencing has to be used. In the near future, the precise role of HLA alleles in transplantation and disease susceptibility is likely to be established unambiguously.

  2. THE PERFORMANCE OF UPLAND RICE ESTABLISHED ON ALANG-ALANG DOMINATED AREA AFTER VARIOUS TECHNIQUES OF ALANG-ALANG CONTROL

    Directory of Open Access Journals (Sweden)

    S. TJITROSEMITO

    1992-01-01

    Full Text Available Pot experiment to investigate the performance of upland rice in a previously alang-alang dominated area was conducted under greenhouse condition at BIOTROP, Bogor, Indonesia from November 1986 to May 1989. The treatments were factorially combined, replicated 5 times and randomized completely. The first factor was alang-alang control consisting of 5 different techniques, i.e. (1 glyphosate applied at 2.2 kg a.e./ha; (2 imazapyr applied at 1.5 kg a.e./ha; (3 dalapon applied twice at 7.4 + 7.4 kg a.i./ha; (4 slashing followed by soil cultivation; (5 slashing of alang-alang only; while the second factor was nitrogen fertilizer at 4 different levels, i.e. (1 0 kg N/ha, (2 60 kg N/ha, (3 120 kg N/ha given twice, 60 kg N/ha at planting time and 60 kg N/ha at 38 dap, (4 180 kg N/ha given twice, 90 kg N/ha at planting and 90 kg N/ha at 38 dap. Plant height (cm, tiller number/pot, productive tiller (%, panicle length (cm, spikelets/panicle, empty spikelet (%, weight 1000 grains (g and grain yield (ton/ha were observed. Upland rice grown with zero tillage technique using glyphosate (2.2 kg a.i./ha or dalapon (14.8 kg a.i./ha performed as good as or even better than manual cultivation. Imazapyr at 1.5 kg a.e./ha was phytotoxic to rice planted 1 month after spraying. The application of N fertilizer lower than 60 kg N/ha was not sufficient, but more than 60 kg N/ha was too high; it stimulated the production of too many tillers, with high percentage of unproductive tillers and empty grains.

  3. Detection of breast cancer using advanced techniques of data mining with neural networks

    International Nuclear Information System (INIS)

    Ortiz M, J. A.; Celaya P, J. M.; Martinez B, M. R.; Solis S, L. O.; Castaneda M, R.; Garza V, I.; Martinez F, M.; Lopez H, Y.; Ortiz R, J. M.

    2016-10-01

    The breast cancer is one of the biggest health problems worldwide, is the most diagnosed cancer in women and prevention seems impossible since its cause is unknown, due to this; the early detection has a key role in the patient prognosis. In developing countries such as Mexico, where access to specialized health services is minimal, the regular clinical review is infrequent and there are not enough radiologists; the most common form of detection of breast cancer is through self-exploration, but this is only detected in later stages, when is already palpable. For these reasons, the objective of the present work is the creation of a system of computer assisted diagnosis (CAD x) using information analysis techniques such as data mining and advanced techniques of artificial intelligence, seeking to offer a previous medical diagnosis or a second opinion, as if it was a second radiologist in order to reduce the rate of mortality from breast cancer. In this paper, advances in the design of computational algorithms using computer vision techniques for the extraction of features derived from mammograms are presented. Using data mining techniques of data mining is possible to identify patients with a high risk of breast cancer. With the information obtained from the mammography analysis, the objective in the next stage will be to establish a methodology for the generation of imaging bio-markers to establish a breast cancer risk index for Mexican patients. In this first stage we present results of the classification of patients with high and low risk of suffering from breast cancer using neural networks. (Author)

  4. Establishment of screening technique for mutant cell and analysis of base sequence in the mutation

    International Nuclear Information System (INIS)

    Sofuni, Toshio; Nomi, Takehiko; Yamada, Masami; Masumura, Kenichi

    2000-01-01

    This research project aimed to establish an easy and quick detection method for radiation-induced mutation using molecular-biological techniques and an effective analyzing method for the molecular changes in base sequence. In this year, Spi mutants derived from γ-radiation exposed mouse were analyzed by PCR method and DNA sequence method. Male transgenic mice were exposed to γ-ray at 5,10, 50 Gy and the transgene was taken out from the genome DNA from the spleen in vivo packaging method. Spi mutant plaques were obtained by infecting the recovered phage to E. coli. Sequence analysis for the mutants was made using ALFred DNA sequencer and SequiTherm TM Long-Red Cycle sequencing kit. Sequence analysis was carried out for 41 of 50 independent Spi mutants obtained. The deletions were classified into 4 groups; Group 1 included 15 mutants that were characterized with a large deletion (43 bp-10 kb) with a short homologous sequence. Group 2 included 11 mutants of a large deletion having no homologous sequence at the connecting region. Group 3 included 11 mutants having a short deletion of less than 20 bp, which occurred in the non-repetitive sequence of gam gene and possibly caused by oxidative breakage of DNA or recombination of DNA fragment produced by the breakage. Group 4 included 4 mutants having deletions as short as 20 bp or less in the repetitive sequence of gam gene, resulting in an alteration of the reading frame. Thus, the synthesis of Gam protein was terminated by the appearance of TGA between code 13 and 14 of redB gene, leading to inactivation of gam gene and redBA gene. These results indicated that most of Spi mutants had a deletion in red/gam region and the deletions in more than half mutants occurred in homologous sequences as short as 8 bp. (M.N.)

  5. Prospects of establishing food irradiation facilities in Kenya

    International Nuclear Information System (INIS)

    Mustapha, A.O.; Patel, J.P.; Rathore, I.V.S.; Hashim, N.O.; Kinyua, A.M.

    2001-01-01

    Full text: A national project of food irradiation in the country is being proposed. At present there are no facilities for food irradiation (and food irradiation research) in Kenya. This report is therefore largely comparative between the traditional and the conventional food preservation methods on the one hand and the irradiation technique on the other. The report is also based on information from other countries where food irradiation is practiced (Kawabata, 1981) or is being also contemplated (Diop et al, 1997), as well as on the relevant report of the International Atomic Energy Agency (IAEA) on this topic (IAEA, 1993). The paper presents the statement of the research problem, i.e., in Kenya large quantities of food and other farm produces go to waste annually as a result of the inadequacies of the preservation techniques currently in use. These (other) preservation techniques, although often less controversial than the irradiation techniques, have also been found to be more expensive to run when compared to irradiation techniques. Such techniques, presently employed in Kenya, include the traditional methods (e.g. sun drying, smoke and fire drying, etc.) and modern techniques such as freezing or refrigeration, lyophilization, etc., as well as application of chemicals like insecticides and fumigants. The latter combines the disadvantages of high costs with environmental pollution and associated health risks. In this preliminary research, aimed at studying the prospects of a national food irradiation project, the following food items that are selected for their importance to the economy of the country, include potatoes, rice, maize, coffee, tea, various fruits, fish and meat. The paper also explores the economic feasibility as well as the human and technological requirements of establishing a commercial food irradiation plant, with aim of assessing the applicability of food irradiation as alternative or a complimentary approach for preservation technique in

  6. Cellular uptake and intracellular fate of engineered nanoparticles: a review on the application of imaging techniques.

    Science.gov (United States)

    Tantra, Ratna; Knight, Alex

    2011-09-01

    The use of imaging tools to probe nanoparticle-cell interactions will be crucial to elucidating the mechanisms of nanoparticle-induced toxicity. Of particular interest are mechanisms associated with cell penetration, translocation and subsequent accumulation inside the cell, or in cellular compartments. The objective of the present paper is to review imaging techniques that have been previously used in order to assess such interactions, and new techniques with the potential to be useful in this area. In order to identify the most suitable techniques, they were evaluated and matched against a list of evaluation criteria. We conclude that limitations exist with all of the techniques and the ultimate choice will thus depend on the needs of end users, and their particular application. The state-of-the-art techniques appear to have the least limitations, despite the fact that they are not so well established and still far from being routine. For example, super-resolution microscopy techniques appear to have many advantages for understanding the details of the interactions between nanoparticles and cells. Future research should concentrate on further developing or improving such novel techniques, to include the development of standardized methods and appropriate reference materials.

  7. Comparison of a commercial blood cross-matching kit to the standard laboratory method for establishing blood transfusion compatibility in dogs.

    Science.gov (United States)

    Guzman, Leo Roa; Streeter, Elizabeth; Malandra, Allison

    2016-01-01

    To evaluate the accuracy of a commercial blood transfusion cross-match kit when compared to the standard laboratory method for establishing blood transfusion compatibility. A prospective observational in intro study performed from July 2009 to July 2013. Private referral veterinary center. Ten healthy dogs, 11 anemic dogs, and 24 previously transfused dogs. None. Forty-five dogs were enrolled in a prospective study in order to compare the standard blood transfusion cross-match technique to a commercial blood transfusion cross-matching kit. These dogs were divided into 3 different groups that included 10 healthy dogs (control group), 11 anemic dogs in need of a blood transfusion, and 24 sick dogs that were previously transfused. Thirty-five dogs diagnosed with anemia secondary to multiple disease processes were cross-matched using both techniques. All dogs cross-matched via the kit had a compatible major and minor result, whereas 16 dogs out of 45 (35%) had an incompatible cross-match result when the standard laboratory technique was performed. The average time to perform the commercial kit was 15 minutes and this was 3 times shorter than the manual cross-match laboratory technique that averaged 45-50 minutes to complete. While the gel-based cross-match kit is quicker and less technically demanding than standard laboratory cross-match procedures, microagglutination and low-grade hemolysis are difficult to identify by using the gel-based kits. This could result in transfusion reactions if the gel-based kits are used as the sole determinant of blood compatibility prior to transfusion. Based on our results, the standard manual cross-match technique remains the gold standard test to determine blood transfusion compatibility. © Veterinary Emergency and Critical Care Society 2016.

  8. Establishment of neurovascular congruency in the mouse whisker system by an independent patterning mechanism.

    Science.gov (United States)

    Oh, Won-Jong; Gu, Chenghua

    2013-10-16

    Nerves and vessels often run parallel to one another, a phenomenon that reflects their functional interdependency. Previous studies have suggested that neurovascular congruency in planar tissues such as skin is established through a "one-patterns-the-other" model, in which either the nervous system or the vascular system precedes developmentally and then instructs the other system to form using its established architecture as a template. Here, we find that, in tissues with complex three-dimensional structures such as the mouse whisker system, neurovascular congruency does not follow the previous model but rather is established via a mechanism in which nerves and vessels are patterned independently. Given the diversity of neurovascular structures in different tissues, guidance signals emanating from a central organizer in the specific target tissue may act as an important mechanism to establish neurovascular congruency patterns that facilitate unique target tissue function. Copyright © 2013 Elsevier Inc. All rights reserved.

  9. Establishing a community-wide DNA barcode library as a new tool for arctic research.

    Science.gov (United States)

    Wirta, H; Várkonyi, G; Rasmussen, C; Kaartinen, R; Schmidt, N M; Hebert, P D N; Barták, M; Blagoev, G; Disney, H; Ertl, S; Gjelstrup, P; Gwiazdowicz, D J; Huldén, L; Ilmonen, J; Jakovlev, J; Jaschhof, M; Kahanpää, J; Kankaanpää, T; Krogh, P H; Labbee, R; Lettner, C; Michelsen, V; Nielsen, S A; Nielsen, T R; Paasivirta, L; Pedersen, S; Pohjoismäki, J; Salmela, J; Vilkamaa, P; Väre, H; von Tschirnhaus, M; Roslin, T

    2016-05-01

    DNA sequences offer powerful tools for describing the members and interactions of natural communities. In this study, we establish the to-date most comprehensive library of DNA barcodes for a terrestrial site, including all known macroscopic animals and vascular plants of an intensively studied area of the High Arctic, the Zackenberg Valley in Northeast Greenland. To demonstrate its utility, we apply the library to identify nearly 20 000 arthropod individuals from two Malaise traps, each operated for two summers. Drawing on this material, we estimate the coverage of previous morphology-based species inventories, derive a snapshot of faunal turnover in space and time and describe the abundance and phenology of species in the rapidly changing arctic environment. Overall, 403 terrestrial animal and 160 vascular plant species were recorded by morphology-based techniques. DNA barcodes (CO1) offered high resolution in discriminating among the local animal taxa, with 92% of morphologically distinguishable taxa assigned to unique Barcode Index Numbers (BINs) and 93% to monophyletic clusters. For vascular plants, resolution was lower, with 54% of species forming monophyletic clusters based on barcode regions rbcLa and ITS2. Malaise catches revealed 122 BINs not detected by previous sampling and DNA barcoding. The insect community was dominated by a few highly abundant taxa. Even closely related taxa differed in phenology, emphasizing the need for species-level resolution when describing ongoing shifts in arctic communities and ecosystems. The DNA barcode library now established for Zackenberg offers new scope for such explorations, and for the detailed dissection of interspecific interactions throughout the community. © 2015 John Wiley & Sons Ltd.

  10. Clinical outcomes of Laparoscopically Assisted Vaginal Hysterectomy at patients who had previous abdominopelvic surgery

    Directory of Open Access Journals (Sweden)

    Ali Riza Odabasi

    2007-03-01

    Full Text Available OBJECTIVE: To determine clinical outcomes of Laparoscopically Assisted Vaginal Hysterectomy (LAVH at patients who had previous abdominopelvic surgery.\tDesign: A clinical observational, prospective, non randomised trial comparing outcomes of 13 patients who had previous abdominopelvic surgery with outcomes of 19 patients who had not surgery.\tSetting: Adnan Menderes University Faculty of Medicine, Department of Obstetrics and Gynecology.\tPatients: Thirty-two subjects [average age 51,1±6,9 (37-66] who had indication of total abdominal hysterectomy and bilateral\tsalpingooferectomy due to benign pathologies.\tInterventions: According to ACOG, LAVH was performed by using the Garry technique at the trocar insertions, the Reich technique\tat the laparoscopic phase and the Heaney technique at the vaginal phase by the same operator. After adhesiolysis and diagnostic procedures, ureters were dissected medially. By coagulating, bilateral round and infundibulopelvic ligaments were cut after the\tmobilisation of bladder. The operation was completed by the same operation team by vaginal approach consequently. At all operations, 80 W unipolar or 150 W bipolar diathermic dissection and 25-35 W unipolar diathermic cutting were performed.\tMain outcome measures: Age, parity, menopausal status, preoperative indications, type of previous abdominopelvic surgey and incision, intraoperative indications, adhesion scores, rate of unintended laparotomy, operative time, uterus weight, loss of blood,\tcomplications, postoperative pain scores and analgesic requirements, time necessary for returning to normal intestinal function, length of hospitalisation and rate of readmission to hospital.\tRESULTS: When compared with the patients who had not previous abdominopelvic surgery, all adhesion scores, uterus weight, operative time and the number of total postoperative complications were found significantly high at patients who had previous\tsurgery. Loss of blood, the rate

  11. Books Average Previous Decade of Economic Misery

    Science.gov (United States)

    Bentley, R. Alexander; Acerbi, Alberto; Ormerod, Paul; Lampos, Vasileios

    2014-01-01

    For the 20th century since the Depression, we find a strong correlation between a ‘literary misery index’ derived from English language books and a moving average of the previous decade of the annual U.S. economic misery index, which is the sum of inflation and unemployment rates. We find a peak in the goodness of fit at 11 years for the moving average. The fit between the two misery indices holds when using different techniques to measure the literary misery index, and this fit is significantly better than other possible correlations with different emotion indices. To check the robustness of the results, we also analysed books written in German language and obtained very similar correlations with the German economic misery index. The results suggest that millions of books published every year average the authors' shared economic experiences over the past decade. PMID:24416159

  12. Kidnapping Detection and Recognition in Previous Unknown Environment

    Directory of Open Access Journals (Sweden)

    Yang Tian

    2017-01-01

    Full Text Available An unaware event referred to as kidnapping makes the estimation result of localization incorrect. In a previous unknown environment, incorrect localization result causes incorrect mapping result in Simultaneous Localization and Mapping (SLAM by kidnapping. In this situation, the explored area and unexplored area are divided to make the kidnapping recovery difficult. To provide sufficient information on kidnapping, a framework to judge whether kidnapping has occurred and to identify the type of kidnapping with filter-based SLAM is proposed. The framework is called double kidnapping detection and recognition (DKDR by performing two checks before and after the “update” process with different metrics in real time. To explain one of the principles of DKDR, we describe a property of filter-based SLAM that corrects the mapping result of the environment using the current observations after the “update” process. Two classical filter-based SLAM algorithms, Extend Kalman Filter (EKF SLAM and Particle Filter (PF SLAM, are modified to show that DKDR can be simply and widely applied in existing filter-based SLAM algorithms. Furthermore, a technique to determine the adapted thresholds of metrics in real time without previous data is presented. Both simulated and experimental results demonstrate the validity and accuracy of the proposed method.

  13. Revision and simplification of the boarding previous minimum of the lumbar column

    International Nuclear Information System (INIS)

    Lazannec, JY; Del Vecchio, R; Ramare, S; Saillant, G

    2001-01-01

    This paper describes the boarding retroperineal previous minimum, which provides access at any level discal and vertebral between T12 and S1. It is carried out a technique of dissection retroperineal that facilitates the renal and duodenum-pancreatic mobilization to consent to the face previous left of the whole lumbar column and of the thoracic-lumbar union. They were carried out careful anatomical dissections in fresh cadavers and preserved to determine the topography and the anatomical relationships of interest and this way to develop a sure boarding and easily reproducible. Special attention has been paid to the description of the lumbar veins and the anastomosis between the vein renal left and the hemiacigos system for the exhibition of the expensive left anterolateral of T12 and L1. A series of 94 patients is reported with lesions caused by traumas or degenerative processes. For all the lumbar levels, even in-patient with antecedents of surgery intraperitoneal, the boarding minimum retroperitoneal, was safe for the kidneys, ureters, spleen, hypo gastric plexus and duodenum-pancreatic union. Better cosmetic results are reported, decrease of the time surgical, scarce bled intraoperatory and easiness for the decortications and placement of implants. The previous boarding minimum retro peritoneal of the column developed starting from the boarding classic retroperineals, offers significant advantages on the endoscopic techniques, which require sophisticated machinery and they are technically plaintiffs. The exhibition of all the lumbar levels, as well as the reduction maneuvers and placement of implants, they can be carried out with easiness without causing muscular damage

  14. Establishment of screening method for effective vaccination using radiolabelled probe

    International Nuclear Information System (INIS)

    Nomaguchi, Hiroko; Yogi, Yasuko

    1998-01-01

    Aiming to develop a screening method for effective vaccination, an investigation was made to establish basic techniques for evaluating cytokine producing abilities of host cells after immunization to mycobacterium leprae. In this study, proliferation of the bacterium was investigated with immunodeficient mice such as BALB/cA-nu/nu, CB-scid, aly/ + and aly/aly and the respective normal mice. When the splenic cells from BALB/cA mouse sensitized with M. leprae (ip, 5 days) was challenged with its cell lysate, γ-IFN was produced, whereas its production was not observed in those from sensitive mouse BALB/cA-nu/nu. In addition, it was suggested that cells which could induce γ-IFN in response to IL-12 were extremely limited in the nude mouse. On the contrary, for IL-18, γ-IFN was inducible in the nude mouse when anti-CD3 was previously coated, indicating that it is difficult to evaluate the efficacy of vaccination only by measuring the productions of IL-12 and IL-18. Therefore, it seems better to determine the amount of γ-IFN protein induced by resensitization with the antigen in the splenic cells. (M.N.)

  15. Establishment of screening method for effective vaccination using radiolabelled probe

    Energy Technology Data Exchange (ETDEWEB)

    Nomaguchi, Hiroko; Yogi, Yasuko [National Inst. of Infectious Deseases, Tokyo (Japan)

    1998-02-01

    Aiming to develop a screening method for effective vaccination, an investigation was made to establish basic techniques for evaluating cytokine producing abilities of host cells after immunization to mycobacterium leprae. In this study, proliferation of the bacterium was investigated with immunodeficient mice such as BALB/cA-nu/nu, CB-scid, aly/{sup +} and aly/aly and the respective normal mice. When the splenic cells from BALB/cA mouse sensitized with M. leprae (ip, 5 days) was challenged with its cell lysate, {gamma}-IFN was produced, whereas its production was not observed in those from sensitive mouse BALB/cA-nu/nu. In addition, it was suggested that cells which could induce {gamma}-IFN in response to IL-12 were extremely limited in the nude mouse. On the contray, for IL-18, {gamma}-IFN was inducible in the nude mouse when anti-CD3 was previously coated, indicating that it is difficult to evaluate the efficacy of vaccination only by measuring the productions of IL-12 and IL-18. Therefore, it seems better to determine the amount of {gamma}-IFN protein induced by resensitization with the antigen in the splenic cells. (M.N.)

  16. IDENTIFICATION OF CANINE VISCERAL LEISHMANIASIS IN A PREVIOUSLY UNAFFECTED AREA BY CONVENTIONAL DIAGNOSTIC TECHNIQUES AND CELL-BLOCK FIXATION

    Directory of Open Access Journals (Sweden)

    Tuanne Rotti ABRANTES

    2016-01-01

    Full Text Available After the report of a second case of canine visceral leishmaniasis (CVL in São Bento da Lagoa, Itaipuaçu, in the municipality of Maricá, Rio de Janeiro State, an epidemiological survey was carried out, through active search, totaling 145 dogs. Indirect immunofluorescence assay (IFA, enzyme-linked immunosorbent assay (ELISA, and rapid chromatographic immunoassay based on dual-path platform (DPP(r were used to perform the serological examinations. The parasitological diagnosis of cutaneous fragments was performed by parasitological culture, histopathology, and immunohistochemistry. In the serological assessment, 21 dogs were seropositive by IFA, 17 by ELISA, and 11 by DPP(r, with sensitivity of 66.7%, 66.7% and 50%, and specificity of 87.2%, 90.2% and 94%, respectively for each technique. The immunohistochemistry of bone marrow using the cell-block technique presented the best results, with six positive dogs found, three of which tested negative by the other parasitological techniques. Leishmania sp. was isolated by parasitological culture in three dogs. The detection of autochthonous Leishmania infantum in Itaipuaçu, and the high prevalence of seropositive dogs confirm the circulation of this parasite in the study area and alert for the risk of expansion in the State of Rio de Janeiro.

  17. Spectrophotometric determination of uranium by previous extraction chromatography separation in polimetalic mineral, phosphorites and technological licours

    International Nuclear Information System (INIS)

    Moreno Bermudez, J.; Cabrera Quevedo, C.; Alfonso Mendez, L.; Rodriguez Aguilera, M.

    1994-01-01

    The development of an analytical procedure for spectrophotometric determination of uranium in polimetalic mineral, phosphorites and technological licours is described. The method is based on the previous separation of interfering elements by extraction chromatography and on spectrophotometric determination of uranium (IV) with arsenazo III in concentrated hydrochloric acid. Tributyl phosphate impregnate on politetrafluoroethylene is used as stationary phase and 5.5 M nitric acid is used as movie phase. The influence of matrix-component elements was studies. The development procedure was applied to real samples, being the results compared with those obtained by other well established analytical methods like gamma-spectrometry, laser fluorimetric, spectrophotometry previous uranium separation by liquid liquid extraction and anion exchange. The reproducibility is evaluated and the detection limited has been established for each studied matrix. A procedure for correcting the thorium interference has been developed for samples with a Th/ 3U8O higher than 0.2

  18. Pulse holographic measurement techniques

    International Nuclear Information System (INIS)

    Kim, Cheol Jung; Baik, Seong Hoon; Hong, Seok Kyung; Kim, Jeong Moog; Kim, Duk Hyun

    1992-01-01

    With the development of laser, remote inspection techniques using laser have been growing on. The inspection and measurement techniques by pulse holography are well-established technique for precise measurement, and widely used in various fields of industry now. In nuclear industry, this technology is practically used because holographic inspection is remote, noncontact, and precise measurement technique. In relation to remote inspection technology in nuclear industry, state-of-the art of pulse HNDT (Holographic non-destructive testing) and holographic measurement techniques are examined. First of all, the fundamental principles as well as practical problems for applications are briefly described. The fields of pulse holography have been divided into the HNDT, flow visualization and distribution study, and other application techniques. Additionally holographic particle study, bubble chamber holography, and applications to other visualization techniques are described. Lastly, the current status for the researches and applications of pulse holography to nuclear industry which are carried out actively in Europe and USA, is described. (Author)

  19. Artificial intelligence techniques in Prolog

    CERN Document Server

    Shoham, Yoav

    1993-01-01

    Artificial Intelligence Techniques in Prolog introduces the reader to the use of well-established algorithmic techniques in the field of artificial intelligence (AI), with Prolog as the implementation language. The techniques considered cover general areas such as search, rule-based systems, and truth maintenance, as well as constraint satisfaction and uncertainty management. Specific application domains such as temporal reasoning, machine learning, and natural language are also discussed.Comprised of 10 chapters, this book begins with an overview of Prolog, paying particular attention to Prol

  20. Is the prefrontal cortex necessary for establishing cognitive sets?

    DEFF Research Database (Denmark)

    Rowe, James B; Sakai, Katsuyuki; Lund, Torben E

    2007-01-01

    first instructed as to whether to perform a spatial or a verbal working memory task and then given spatial and verbal items after a delay of 4-12 s. The patients showed an increase in switch costs, making more errors by repeating what they had done on the previous trial. They were able to establish...

  1. Use of molecular techniques in bioremediation.

    Science.gov (United States)

    Płaza, G; Ulfig, K; Hazen, T C; Brigmon, R L

    2001-01-01

    In a practical sense, biotechnology is concerned with the production of commercial products generated by biological processes. More formally, biotechnology may be defined as "the application of scientific and engineering principles to the processing of material by biological agents to provide goods and services" (Cantor, 2000). From a historical perspective, biotechnology dates back to the time when yeast was first used for beer or wine fermentation, and bacteria were used to make yogurt. In 1972, the birth of recombinant DNA technology moved biotechnology to new heights and led to the establishment of a new industry. Progress in biotechnology has been truly remarkable. Within four years of the discovery of recombinant DNA technology, genetically modified organisms (GMOs) were making human insulin, interferon, and human growth hormone. Now, recombinant DNA technology and its products--GMOs are widely used in environmental biotechnology (Glick and Pasternak, 1988; Cowan, 2000). Bioremediation is one of the most rapidly growing areas of environmental biotechnology. Use of bioremediation for environmental clean up is popular due to low costs and its public acceptability. Indeed, bioremediation stands to benefit greatly and advance even more rapidly with the adoption of molecular techniques developed originally for other areas of biotechnology. The 1990s was the decade of molecular microbial ecology (time of using molecular techniques in environmental biotechnology). Adoption of these molecular techniques made scientists realize that microbial populations in the natural environments are much more diverse than previously thought using traditional culture methods. Using molecular ecological methods, such as direct DNA isolation from environmental samples, denaturing gradient gel electrophoresis (DGGE), PCR methods, nucleic acid hybridization etc., we can now study microbial consortia relevant to pollutant degradation in the environment. These techniques promise to

  2. Establishment and initial experiences from the Danish Ventral Hernia Database

    DEFF Research Database (Denmark)

    Helgstrand, F; Rosenberg, J; Bay-Nielsen, M

    2010-01-01

    , use of mesh or no mesh, type of suture material, and placement of the mesh. A total of 5,629 elective and 661 acute ventral hernia repairs were registered. After the first 2 years the registration rate was 70%. CONCLUSION: The first national ventral hernia database has been established. Preliminary...... of the Danish Ventral Hernia Database (DVHD). Furthermore, the first 2-year data from 2007 to 2008 are presented. METHODS: Registrations were based on surgeons' web registrations and validated by cross checking with data from the Danish National Patient Register. RESULTS: The DVHD was established in June 2006...... and is based on prospective online web-registration of perioperative data, and individualised tracking of follow up data. During the first 2 years (2007-2008) data showed a large variation in almost all aspects of ventral hernia repair regarding surgical technique, use of open versus laparoscopic technique...

  3. The biological response of plucked human hair to low-dose radiation: a measure of individual radiosensitivity and a technique for biological dosimetry

    International Nuclear Information System (INIS)

    Swain, D.

    1997-01-01

    It is often assumed that the effects of radiation are linear with dose and that high dose effects can be extrapolated to low dose levels. However, there are a variety of mechanisms which can alter the response at low doses. The most important of these relate to induced sensitivity or induced repair mechanisms. It is therefore important that this area is studied in more depth by looking at the molecular effects and damage to cells at low doses. It is well known that there are certain rare genetic syndromes which predispose individuals to cancer, e.g. ataxia telangiectasia. It is also probable that there is a large range of sensitivity in the natural variation of individuals to the risk of radiation-induced cancer. It is proposed that radiosensitivity is studied using stimulated lymphocytes from whole blood and the technique extended to look at the effects in cell cultures established from human hair. Radiation treatment of cell cultures established from plucked human hair has been previously advocated as a non-invasive technique for non-uniform biological dosimetry and it is proposed that these techniques are adapted to the use of hair to estimate individual radiosensitivity. The aim is to establish and optimize these techniques for culturing keratinocytes from plucked human hair follicles with a view to study biological markers for the subsequent assessment of radiosensitivity. Preliminary results are promising and suggest that the technique for culturing keratinocytes from hair presents a feasible approach. Results from this primary cell culture technique and results from the comparison of the micronuclei data obtained from the cell cultures and stimulated lymphocytes will be presented. (author)

  4. Tumescent mastectomy technique in autologous breast reconstruction.

    Science.gov (United States)

    Vargas, Christina R; Koolen, Pieter G L; Ho, Olivia A; Ricci, Joseph A; Tobias, Adam M; Lin, Samuel J; Lee, Bernard T

    2015-10-01

    Use of the tumescent mastectomy technique has been reported to facilitate development of a hydrodissection plane, reduce blood loss, and provide adjunct analgesia. Previous studies suggest that tumescent dissection may contribute to adverse outcomes after immediate implant reconstruction; however, its effect on autologous microsurgical reconstruction has not been established. A retrospective review was conducted of all immediate microsurgical breast reconstruction procedures at a single academic center between January 2004 and December 2013. Records were queried for age, body mass index, mastectomy weight, diabetes, hypertension, smoking, preoperative radiation, reconstruction flap type, and autologous flap weight. Outcomes of interest were mastectomy skin necrosis, complete and partial flap loss, return to the operating room, breast hematoma, seroma, and infection. There were 730 immediate autologous breast reconstructions performed during the study period; 46% with the tumescent dissection technique. Groups were similar with respect to baseline patient and procedural characteristics. Univariate analysis revealed no significant difference in the incidence of mastectomy skin necrosis, complete or partial flap loss, return to the operating room, operative time, estimated blood loss, recurrence, breast hematoma, seroma, or infection in patients undergoing tumescent mastectomy. Multivariate analysis also demonstrated no significant association between the use of tumescent technique and postoperative breast mastectomy skin necrosis (P = 0.980), hematoma (P = 0.759), or seroma (P = 0.340). Use of the tumescent dissection technique during mastectomy is not significantly associated with adverse outcomes after microsurgical breast reconstruction. Despite concern for its impact on implant reconstruction, our findings suggest that this method can be used safely preceding autologous procedures. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. Treatment of uncertainties in the existence of free berths with risk analysis techniques. Establishment of policies in port of Cadiz (SPAIN)

    Energy Technology Data Exchange (ETDEWEB)

    Awad Nuñez, S.; Camarero Orive, A.; Romero Sanchez-Brunete, M.; Camarero Orive, A.; Gonzalez Cancelas, N.

    2016-07-01

    This research discusses the challenges involved in the treatment of uncertainties in the existence of free berths during the arrival of cruise ships at seaports. Pursuing this goal, a three-step methodology is adopted: 1) Identifying risk sources and critical risk variables and how they are related; 2) Fitting the Probability Distribution Functions that best represent the behaviour of each critical risk variable; and 3) Simulating the probability of a ship having to wait because there are no free berths using a technique that combines statistical concepts (random sampling) with the ability of computers to generate pseudo-random numbers and automate estimations of the values of the set of critical risk variables. The innovative use of risk analysis techniques in this field allows the establishment of policies to improve the planning and management of port infrastructure, for example, deciding when it is necessary to work to increase the number of berths. As a case of study, we applied this methodology to study whether the enlargement of the wharf in the port of Cadiz (Spain) is necessary right now considering the number of cruise ships that have arrived at the port in the past three years, their date and hour of arrival, their length and draught, the duration of their stay in port and their waiting time before being able to enter the port. This action would require moving logistics activities to a new terminal, but would bring to the city the opportunity to rethink the seafront, introducing new cruiser links with the city centre and developing a better seaport-city integration. (Author)

  6. Winter climate limits subantarctic low forest growth and establishment.

    Science.gov (United States)

    Harsch, Melanie A; McGlone, Matt S; Wilmshurst, Janet M

    2014-01-01

    Campbell Island, an isolated island 600 km south of New Zealand mainland (52 °S, 169 °E) is oceanic (Conrad Index of Continentality  =  -5) with small differences between mean summer and winter temperatures. Previous work established the unexpected result that a mean annual climate warming of c. 0.6 °C since the 1940's has not led to upward movement of the forest limit. Here we explore the relative importance of summer and winter climatic conditions on growth and age-class structure of the treeline forming species, Dracophyllum longifolium and Dracophyllum scoparium over the second half of the 20th century. The relationship between climate and growth and establishment were evaluated using standard dendroecological methods and local climate data from a meteorological station on the island. Growth and establishment were correlated against climate variables and further evaluated within hierarchical regression models to take into account the effect of plot level variables. Winter climatic conditions exerted a greater effect on growth and establishment than summer climatic conditions. Establishment is maximized under warm (mean winter temperatures >7 °C), dry winters (total winter precipitation <400 mm). Growth, on the other hand, is adversely affected by wide winter temperature ranges and increased rainfall. The contrasting effect of winter warmth on growth and establishment suggests that winter temperature affects growth and establishment through differing mechanisms. We propose that milder winters enhance survival of seedlings and, therefore, recruitment, but increases metabolic stress on established plants, resulting in lower growth rates. Future winter warming may therefore have complex effects on plant growth and establishment globally.

  7. Establishment of ultra trace nuclear material analysis system

    International Nuclear Information System (INIS)

    Song, Kyuseok; Jee, Kwangyong; Lee, Changheon

    2012-05-01

    Highly accurate and precise analysis of ultra trace nuclear materials contained in swipe samples and environmental samples is required to improve the national nuclear transparency and the international nuclear security. The objectives of the first stage of this project are to develop the techniques for bulk analysis of environmental samples and the elemental techniques for particle analysis using FT-TIMS. To accomplish the objectives, state-of-the-art analytical instruments were set up followed by the development of the techniques for screening of nuclear materials, chemical treatement, particle handling, isotopic measurements using TIMS and ICP-MS, and fabrication of uranium microparticles. The verifications of the developed techniques were carried out by measurement of reference materials, and by participation to interlaboratory comparison programs. In additon, the establishement of a quality management system and the performance of the analysis of QC samples for IAEA-NWAL qualification were carried out to obtain the international accreditation for the related analytical system. In this report, the results of research and developments, and the achievements to obtain the international accreditation were summarized

  8. 48 CFR 1631.203-70 - Allocation techniques.

    Science.gov (United States)

    2010-10-01

    ... shall consistently apply the methods and techniques established to classify direct and indirect costs... meant to be exhaustive, but rather are examples of allocation methods that may be acceptable under... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Allocation techniques. 1631...

  9. Outcome of trial of scar in patients with previous caesarean section

    International Nuclear Information System (INIS)

    Khan, B.; Bashir, R.; Khan, W.

    2016-01-01

    Medical evidence indicates that 60-80% of women can achieve vaginal delivery after a previous lower segment caesarean section. Proper selection of patients for trial of scar and vigilant monitoring during labour will achieve successful maternal and perinatal outcome. The objective of our study is to establish the fact that vaginal delivery after one caesarean section has a high success rate in patients with previous one caesarean section for non-recurrent cause. Methods: The study was conducted in Ayub Teaching Abbottabad, Gynae-B Unit. All labouring patients, during the study period of five years, with previous one caesarean section and between 37 weeks to 41 weeks of gestation for a non-recurrent cause were included in the study. Data was recorded on special proforma designed for the purpose. Patients who had previous classical caesarean section, more than one caesarean section, and previous caesarean section with severe wound infection, transverse lie and placenta previa in present pregnancy were excluded. Foetal macrosomia (wt>4 kg) and severe IUGR with compromised blood flow on Doppler in present pregnancy were also not considered suitable for the study. Patients who had any absolute contraindication for vaginal delivery were also excluded. Results: There were 12505 deliveries during the study period. Total vaginal deliveries were 8790 and total caesarean sections were 3715. Caesarean section rate was 29.7%. Out of these 8790 patients, 764 patients were given a trial of scar and 535 patients delivered successfully vaginally (70%). Women who presented with spontaneous onset of labour were more likely to deliver vaginally (74.8%) as compared to induction group (27.1%). Conclusion: Trial of vaginal birth after caesarean (VBAC) in selected cases has great importance in the present era of the rising rate of primary caesarean section. (author)

  10. Influence of previous administration of trans-phenylcyclopropylamine on radioprotective and hypothermic effects of serotonin

    International Nuclear Information System (INIS)

    Misustova, J.; Hosek, B.; Novak, L.; Kautska, J.

    1978-01-01

    The influence of a previous administration of trans-phenylcyclopropylamine (t-PCPA) on radioprotective and hypothermic effects of serotonin was studied in male mice of the H strain, which were given t-PCPA in the dose of 4 mg/kg intraperitoneally 2 or 7 hours before application of serotonin (40 mg/kg, i.p.). The time course of protection was studied for exposures to 800 and 900 R. The results have shown that a previous administration of t-PCPA does not alter the short-time protective effect of serotonin, but that it significantly prolongs the time course of protection. The administration of t-PCPA also affects the starting speed and the duration of the serotonin-induced hypothermic reaction. The established correlation between prolongation of the radioprotective and hypothermic effects of serotonin induced by previous application of t-PCPA supplements the results with the existence of mutual relationship between changes of the energetic exchange and radioresistance of the organism. (author)

  11. Prosthetic valve sparing aortic root replacement: an improved technique.

    Science.gov (United States)

    Leacche, Marzia; Balaguer, Jorge M; Umakanthan, Ramanan; Byrne, John G

    2008-10-01

    We describe a modified surgical technique to treat patients with a previous history of isolated aortic valve replacement who now require aortic root replacement for an aneurysmal or dissected aorta. This technique consists of replacing the aortic root with a Dacron conduit, leaving intact the previously implanted prosthesis, and re-implanting the coronary arteries in the Dacron graft. Our technique differs from other techniques in that we do not leave behind any aortic tissue remnant and also in that we use a felt strip to obliterate any gap between the old sewing ring and the newly implanted graft. In our opinion, this promotes better hemostasis. We demonstrate that this technique is safe, feasible, and results in acceptable outcomes.

  12. Applying contemporary statistical techniques

    CERN Document Server

    Wilcox, Rand R

    2003-01-01

    Applying Contemporary Statistical Techniques explains why traditional statistical methods are often inadequate or outdated when applied to modern problems. Wilcox demonstrates how new and more powerful techniques address these problems far more effectively, making these modern robust methods understandable, practical, and easily accessible.* Assumes no previous training in statistics * Explains how and why modern statistical methods provide more accurate results than conventional methods* Covers the latest developments on multiple comparisons * Includes recent advanc

  13. Establishment of animal model with half-liver cirrhosis

    International Nuclear Information System (INIS)

    Yang Zhenghan; Zhou Cheng; Chen Min; Xie Jingxia; Zhang Yuewu; Hu Bifang; Mo Hongbo; Wu Xiao

    2003-01-01

    Objective: To establish a new cirrhosis model suitable for imaging study. Methods: Via a 4 F catheter, 50-100 μl of carbon tetrachloride was injected into the left or right hepatic artery of 12 dogs fortnightly. Liver functional test, imaging study, and pathological examination were performed in these dogs regularly. Results: As the times of injection increased, necrosis of hepatocytes, fibrosis, and cirrhosis of the liver aggravated. In each dog, cirrhosis was more serious in the half liver with carbon tetrachloride injection than in the other half liver without carbon tetrachloride injection. With this model, it was convenient to perform the imaging study of liver cirrhosis. Conclusion: Animal model with half-liver cirrhosis can be established by combining catheter technique and traditional method

  14. Establishment of a ruminal protein degradation data base for dairy ...

    African Journals Online (AJOL)

    Establishment of a ruminal protein degradation data base for dairy cattle using the in situ polyester bag technique. 2. Energy sources. LJ Erasmus, J Prinsloo, PM Botha, HH Meissner. Abstract. No Abstract. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT.

  15. Establishment of a ruminal protein degradation data base for dairy ...

    African Journals Online (AJOL)

    Establishment of a ruminal protein degradation data base for dairy cattle using the in situ polyester bag technique. 3. Roughages. LJ Erasmus, J Prinsloo, PM Botha, HH Meissner. Abstract. No Abstract. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT.

  16. Alternative Constraint Handling Technique for Four-Bar Linkage Path Generation

    Science.gov (United States)

    Sleesongsom, S.; Bureerat, S.

    2018-03-01

    This paper proposes an extension of a new concept for path generation from our previous work by adding a new constraint handling technique. The propose technique was initially designed for problems without prescribed timing by avoiding the timing constraint, while remain constraints are solving with a new constraint handling technique. The technique is one kind of penalty technique. The comparative study is optimisation of path generation problems are solved using self-adaptive population size teaching-learning based optimization (SAP-TLBO) and original TLBO. In this study, two traditional path generation test problem are used to test the proposed technique. The results show that the new technique can be applied with the path generation problem without prescribed timing and gives better results than the previous technique. Furthermore, SAP-TLBO outperforms the original one.

  17. Establishing Credibility in the Multicultural Classroom: When the Instructor Speaks with an Accent

    Science.gov (United States)

    McLean, Chikako Akamatsu

    2007-01-01

    Applying theories of cultural dimensions, teacher credibility, and nonverbal immediacy, this chapter explores classroom management techniques used by Asian female teachers to establish credibility. (Contains 1 note.)

  18. Winter climate limits subantarctic low forest growth and establishment.

    Directory of Open Access Journals (Sweden)

    Melanie A Harsch

    Full Text Available Campbell Island, an isolated island 600 km south of New Zealand mainland (52 °S, 169 °E is oceanic (Conrad Index of Continentality  =  -5 with small differences between mean summer and winter temperatures. Previous work established the unexpected result that a mean annual climate warming of c. 0.6 °C since the 1940's has not led to upward movement of the forest limit. Here we explore the relative importance of summer and winter climatic conditions on growth and age-class structure of the treeline forming species, Dracophyllum longifolium and Dracophyllum scoparium over the second half of the 20th century. The relationship between climate and growth and establishment were evaluated using standard dendroecological methods and local climate data from a meteorological station on the island. Growth and establishment were correlated against climate variables and further evaluated within hierarchical regression models to take into account the effect of plot level variables. Winter climatic conditions exerted a greater effect on growth and establishment than summer climatic conditions. Establishment is maximized under warm (mean winter temperatures >7 °C, dry winters (total winter precipitation <400 mm. Growth, on the other hand, is adversely affected by wide winter temperature ranges and increased rainfall. The contrasting effect of winter warmth on growth and establishment suggests that winter temperature affects growth and establishment through differing mechanisms. We propose that milder winters enhance survival of seedlings and, therefore, recruitment, but increases metabolic stress on established plants, resulting in lower growth rates. Future winter warming may therefore have complex effects on plant growth and establishment globally.

  19. Winter Climate Limits Subantarctic Low Forest Growth and Establishment

    Science.gov (United States)

    Harsch, Melanie A.; McGlone, Matt S.; Wilmshurst, Janet M.

    2014-01-01

    Campbell Island, an isolated island 600 km south of New Zealand mainland (52°S, 169°E) is oceanic (Conrad Index of Continentality  = −5) with small differences between mean summer and winter temperatures. Previous work established the unexpected result that a mean annual climate warming of c. 0.6°C since the 1940's has not led to upward movement of the forest limit. Here we explore the relative importance of summer and winter climatic conditions on growth and age-class structure of the treeline forming species, Dracophyllum longifolium and Dracophyllum scoparium over the second half of the 20th century. The relationship between climate and growth and establishment were evaluated using standard dendroecological methods and local climate data from a meteorological station on the island. Growth and establishment were correlated against climate variables and further evaluated within hierarchical regression models to take into account the effect of plot level variables. Winter climatic conditions exerted a greater effect on growth and establishment than summer climatic conditions. Establishment is maximized under warm (mean winter temperatures >7 °C), dry winters (total winter precipitation <400 mm). Growth, on the other hand, is adversely affected by wide winter temperature ranges and increased rainfall. The contrasting effect of winter warmth on growth and establishment suggests that winter temperature affects growth and establishment through differing mechanisms. We propose that milder winters enhance survival of seedlings and, therefore, recruitment, but increases metabolic stress on established plants, resulting in lower growth rates. Future winter warming may therefore have complex effects on plant growth and establishment globally. PMID:24691026

  20. [Establishment of data warehouse of needling and moxibustion literature based on data mining].

    Science.gov (United States)

    Wang, Jian-Ling; Li, Ren-Ling; Jia, Chun-Sheng

    2012-02-01

    In order to explore the efficacy specificity and valuable rules of clinical application of needling and moxibustion methods in a large quantity of information from literature, a data warehouse needs being established. On the basis of the original databases of red-hot needle therapy and hydro-acupuncture therapy, and the newly-established databases of acupoint catgut embedding therapy, acupoint application therapy, etc., and in accordance with the characteristics of different types of needling-moxibustion literature information, databases on different subjects were established first. These subject databases constitute a general "literature data warehouse on needling moxibustion methods" composing of multi-subjects and multiple dimensions so as to discover useful regularities about clinical treatment and trials collected in the literature by using data mining techniques. In the present paper, the authors introduce the design of the data warehouse, determination of subjects, establishment of subject relations, application of the administration platform, and application of data. This data warehouse will provide a standard data representation mode, enlarge data attributes and create extensive data links among literature information in the network, and may bring us with considerable convenience and profits in clinical application decision making and scientific research about needling-moxibustion techniques.

  1. Microsurgical techniques for experimental kidney transplantation and general guidelines to establish studies about transplantation immunology Técnicas microcirúrgicas para transplante renal experimental e condutas para estabelecer experimentos sobre imunologia do transplante

    Directory of Open Access Journals (Sweden)

    Paulo Ney Aguiar Martins

    2003-08-01

    Full Text Available Experimental models of organ transplantation played a crucial role to establish the principles of transplantation immunology. The renal transplantation in rodents became the most used model to study the mechanisms of allograft rejection. To perform it, it is necessary to master the microsurgery techniques and the research group should cooperate with other specialists in the field. In this article we review the surgical techniques employed in rats, and we draw guidelines to establish studies about transplantation immunology.Os princípios da imunologia do transplante estabeleceram-se após o surgimento de modelos experimentais. Esses modelos foram fundamentais para descoberta de mecanismos de tolerância imunológica e as bases genéticas da reação de rejeição. Transplante renal em roedores utilizando técnicas de microcirurgia tornou-se o modelo ideal, e abriu um novo horizonte para condução de pesquisas sobre imunologia e fisiologia de transplantes. Neste artigo revisamos as técnicas de transplante renal, e esboçamos diretrizes para elaboração de estudos imunológicos em modelos de rejeição.

  2. The establishment of a protein degradability data base for dairy ...

    African Journals Online (AJOL)

    The establishment of a protein degradability data base for dairy cattle using the nylon bag technique. 1. Protein sources. LJ Erasmus, J Prinsloo, HH Meissner. Abstract. No Abstract. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · AJOL African Journals ...

  3. Consumer attitudes towards the establishment of a national Australian familial cancer research database by the Inherited Cancer Connect (ICCon) Partnership.

    Science.gov (United States)

    Forrest, Laura; Mitchell, Gillian; Thrupp, Letitia; Petelin, Lara; Richardson, Kate; Mascarenhas, Lyon; Young, Mary-Anne

    2018-01-01

    Clinical genetics units hold large amounts of information which could be utilised to benefit patients and their families. In Australia, a national research database, the Inherited Cancer Connect (ICCon) database, is being established that comprises clinical genetic data held for all carriers of mutations in cancer predisposition genes. Consumer input was sought to establish the acceptability of the inclusion of clinical genetic data into a research database. A qualitative approach using a modified nominal group technique was used to collect data through consumer forums conducted in three Australian states. Individuals who had previously received care from Familial Cancer Centres were invited to participate. Twenty-four consumers participated in three forums. Participants expressed positive attitudes about the establishment of the ICCon database, which were informed by the perceived benefits of the database including improved health outcomes for individuals with inherited cancer syndromes. Most participants were comfortable to waive consent for their clinical information to be included in the research database in a de-identified format. As major stakeholders, consumers have an integral role in contributing to the development and conduct of the ICCon database. As an initial step in the development of the ICCon database, the forums demonstrated consumers' acceptance of important aspects of the database including waiver of consent.

  4. A rational framework for production decision making in blood establishments.

    Science.gov (United States)

    Ramoa, Augusto; Maia, Salomé; Lourenço, Anália

    2012-07-24

    SAD_BaSe is a blood bank data analysis software, created to assist in the management of blood donations and the blood production chain in blood establishments. In particular, the system keeps track of several collection and production indicators, enables the definition of collection and production strategies, and the measurement of quality indicators required by the Quality Management System regulating the general operation of blood establishments. This paper describes the general scenario of blood establishments and its main requirements in terms of data management and analysis. It presents the architecture of SAD_BaSe and identifies its main contributions. Specifically, it brings forward the generation of customized reports driven by decision making needs and the use of data mining techniques in the analysis of donor suspensions and donation discards.

  5. Development of fault diagnostic technique using reactor noise analysis

    International Nuclear Information System (INIS)

    Park, Jin Ho; Kim, J. S.; Oh, I. S.; Ryu, J. S.; Joo, Y. S.; Choi, S.; Yoon, D. B.

    1999-04-01

    The ultimate goal of this project is to establish the analysis technique to diagnose the integrity of reactor internals using reactor noise. The reactor noise analyses techniques for the PWR and CANDU NPP(Nuclear Power Plants) were established by which the dynamic characteristics of reactor internals and SPND instrumentations could be identified, and the noise database corresponding to each plant(both Korean and foreign one) was constructed and compared. Also the change of dynamic characteristics of the Ulchin 1 and 2 reactor internals were simulated under presumed fault conditions. Additionally portable reactor noise analysis system was developed so that real time noise analysis could directly be able to be performed at plant site. The reactor noise analyses techniques developed and the database obtained from the fault simulation, can be used to establish a knowledge based expert system to diagnose the NPP's abnormal conditions. And the portable reactor noise analysis system may be utilized as a substitute for plant IVMS(Internal Vibration Monitoring System). (author)

  6. Development of fault diagnostic technique using reactor noise analysis

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jin Ho; Kim, J. S.; Oh, I. S.; Ryu, J. S.; Joo, Y. S.; Choi, S.; Yoon, D. B

    1999-04-01

    The ultimate goal of this project is to establish the analysis technique to diagnose the integrity of reactor internals using reactor noise. The reactor noise analyses techniques for the PWR and CANDU NPP(Nuclear Power Plants) were established by which the dynamic characteristics of reactor internals and SPND instrumentations could be identified, and the noise database corresponding to each plant(both Korean and foreign one) was constructed and compared. Also the change of dynamic characteristics of the Ulchin 1 and 2 reactor internals were simulated under presumed fault conditions. Additionally portable reactor noise analysis system was developed so that real time noise analysis could directly be able to be performed at plant site. The reactor noise analyses techniques developed and the database obtained from the fault simulation, can be used to establish a knowledge based expert system to diagnose the NPP's abnormal conditions. And the portable reactor noise analysis system may be utilized as a substitute for plant IVMS(Internal Vibration Monitoring System). (author)

  7. Ecthyma gangrenosum in the periorbital region in a previously healthy immunocompetent woman without bacteremia

    Directory of Open Access Journals (Sweden)

    Somenath Sarkar

    2016-01-01

    Full Text Available Ecthyma gangrenosum (EG is a cutaneous lesion classically associated with potentially fatal Pseudomonas septicemia in immunocompromised patients. Other bacterial and fungal pathogens have also been implicated. Although EG typically occurs in immunocompromised or neutropenic patients, it may occasionally affect a previously healthy person. The cutaneous findings are characteristic with small indurated papulovesicles progressing rapidly to necrotic ulcers with surrounding erythema and a central black Eschar. While lesions can occur at any site, most are commonly found over the buttocks, perineum, limbs, and axillae. We describe a case of EG in periorbital region in a previously healthy woman who responded to appropriate antibiotic treatment for Pseudomonas. It is very important to establish the diagnosis early so that appropriate systemic antibiotic therapy can be initiated to reduce morbidity and potential mortality.

  8. Mobile depth profiling and sub-surface imaging techniques for historical paintings—A review

    International Nuclear Information System (INIS)

    Alfeld, Matthias; Broekaert, José A.C.

    2013-01-01

    Hidden, sub-surface paint layers and features contain valuable information for the art-historical investigation of a painting's past and for its conservation for coming generations. The number of techniques available for the study of these features has been considerably extended in the last decades and established techniques have been refined. This review focuses on mobile non-destructive subsurface imaging and depth profiling techniques, which allow for the in-situ investigation of easel paintings, i.e. paintings on a portable support. Among the techniques discussed are: X-ray radiography and infrared reflectography, which are long established methods and are in use for several decades. Their capabilities of element/species specific imaging have been extended by the introduction of energy/wavelength resolved measurements. Scanning macro-X-ray fluorescence analysis made it for the first time possible to acquire elemental distribution images in-situ and optical coherence tomography allows for the non-destructive study the surface paint layers in virtual cross-sections. These techniques and their variants are presented next to other techniques, such as Terahertz imaging, Nuclear Magnetic Resonance depth profiling and established techniques for non destructive testing (thermography, ultrasonic imaging and laser based interference methods) applied in the conservation of historical paintings. Next to selected case studies the capabilities and limitations of the techniques are discussed. - Highlights: • All mobile sub-surface and depth-profiling techniques for paintings are reviewed. • The number of techniques available has increased considerably in the last years. • X-ray radiography and infrared reflectography are still the most used techniques. • Scanning macro-XRF and optical coherence tomography begin to establish. • Industrial non destructive testing techniques support the preservation of paintings

  9. Development of human factors evaluation techniques for nuclear power plants

    International Nuclear Information System (INIS)

    Oh, I.S.; Lee, Y.H.; Lee, J.W.; Sim, B.S.

    1999-01-01

    This paper describes development of an operator task simulation analyzer and human factors evaluation techniques performed recently at Korea Atomic Energy Research Institute. The first is the SACOM (Simulation Analyzer with a Cognitive Operator Model) for the assessment of task performance by simulating control room operation. The latter has two objectives: to establish a human factors experiment facility, the Integrated Test Facility (ITF), and to establish techniques for human factors experiments. (author)

  10. Cognitive Support in Teaching Football Techniques

    Science.gov (United States)

    Duda, Henryk

    2009-01-01

    Study aim: To improve the teaching of football techniques by applying cognitive and imagery techniques. Material and methods: Four groups of subjects, n = 32 each, were studied: male and female physical education students aged 20-21 years, not engaged previously in football training; male juniors and minors, aged 16 and 13 years, respectively,…

  11. Validation of an online replanning technique for prostate adaptive radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Peng Cheng; Chen Guangpei; Ahunbay, Ergun; Wang Dian; Lawton, Colleen; Li, X Allen, E-mail: ali@mcw.edu [Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI (United States)

    2011-06-21

    We have previously developed an online adaptive replanning technique to rapidly adapt the original plan according to daily CT. This paper reports the quality assurance (QA) developments in its clinical implementation for prostate cancer patients. A series of pre-clinical validation tests were carried out to verify the overall accuracy and consistency of the online replanning procedure. These tests include (a) phantom measurements of 22 individual patient adaptive plans to verify their accuracy and deliverability and (b) efficiency and applicability of the online replanning process. A four-step QA procedure was established to ensure the safe and accurate delivery of an adaptive plan, including (1) offline phantom measurement of the original plan, (2) online independent monitor unit (MU) calculation for a redundancy check, (3) online verification of plan-data transfer using an in-house software and (4) offline validation of actually delivered beam parameters. The pre-clinical validations demonstrate that the newly implemented online replanning technique is dosimetrically accurate and practically efficient. The four-step QA procedure is capable of identifying possible errors in the process of online adaptive radiotherapy and to ensure the safe and accurate delivery of the adaptive plans. Based on the success of this work, the online replanning technique has been used in the clinic to correct for interfractional changes during the prostate radiation therapy.

  12. Validation of an online replanning technique for prostate adaptive radiotherapy

    International Nuclear Information System (INIS)

    Peng Cheng; Chen Guangpei; Ahunbay, Ergun; Wang Dian; Lawton, Colleen; Li, X Allen

    2011-01-01

    We have previously developed an online adaptive replanning technique to rapidly adapt the original plan according to daily CT. This paper reports the quality assurance (QA) developments in its clinical implementation for prostate cancer patients. A series of pre-clinical validation tests were carried out to verify the overall accuracy and consistency of the online replanning procedure. These tests include (a) phantom measurements of 22 individual patient adaptive plans to verify their accuracy and deliverability and (b) efficiency and applicability of the online replanning process. A four-step QA procedure was established to ensure the safe and accurate delivery of an adaptive plan, including (1) offline phantom measurement of the original plan, (2) online independent monitor unit (MU) calculation for a redundancy check, (3) online verification of plan-data transfer using an in-house software and (4) offline validation of actually delivered beam parameters. The pre-clinical validations demonstrate that the newly implemented online replanning technique is dosimetrically accurate and practically efficient. The four-step QA procedure is capable of identifying possible errors in the process of online adaptive radiotherapy and to ensure the safe and accurate delivery of the adaptive plans. Based on the success of this work, the online replanning technique has been used in the clinic to correct for interfractional changes during the prostate radiation therapy.

  13. Advanced Techniques in Biophysics

    CERN Document Server

    Arrondo, José Luis R

    2006-01-01

    Technical advancements are basic elements in our life. In biophysical studies, new applications and improvements in well-established techniques are being implemented every day. This book deals with advancements produced not only from a technical point of view, but also from new approaches that are being taken in the study of biophysical samples, such as nanotechniques or single-cell measurements. This book constitutes a privileged observatory for reviewing novel applications of biophysical techniques that can help the reader enter an area where the technology is progressing quickly and where a comprehensive explanation is not always to be found.

  14. Nonenhanced MR angiography techniques

    International Nuclear Information System (INIS)

    Lanzman, R.S.; Kroepil, P.; Blondin, D.; Schmitt, P.

    2011-01-01

    Especially in regard to the potential risks for the development of nephrogenic systemic fibrosis (NSF) following the administration of Gadolinium-based contrast material, nonenhanced MR angiography (MRA) methods are becoming ever more important. Besides well-established time-of-flight (TOF) and phase-contrast (PC) MRA, alternative imaging techniques based on balanced steady-state free precession (bSSFP) and turbo-spin-echo (TSE) sequences are increasingly used in combination with or without arterial spin labeling (ASL) strategies. This article provides an overview of the principles and clinical values of different nonenhanced MRA techniques. In addition, recent nonenhanced MRA developments are presented. (orig.)

  15. Intra-urinoma Rendezvous Using a Transconduit Approach to Re-establish Ureteric Integrity

    International Nuclear Information System (INIS)

    Anderson, Hugh; Alyas, Faisal; Edwin, Patrick Joseph

    2005-01-01

    Ureteric discontinuity following injury has been traditionally treated surgically. With the advent of improved interventional instrumentation it is possible to stent these lesions percutaneously, retrogradely or failing that using a combined (rendezvous) technique. We describe an intra-urinoma rendezvous procedure combining a percutaneous antegrade-transconduit retrograde technique of stent insertion to successfully re-establish ureteric integrity that was used following the failure of a percutaneous retrograde approach. We illustrate its usefulness as an alternative to surgery

  16. Using Data-Driven and Process Mining Techniques for Identifying and Characterizing Problem Gamblers in New Zealand

    Directory of Open Access Journals (Sweden)

    Suriadi Suriadi

    2016-12-01

    Full Text Available This article uses data-driven techniques combined with established theory in order to analyse gambling behavioural patterns of 91 thousand individuals on a real-world fixed-odds gambling dataset in New Zealand. This research uniquely integrates a mixture of process mining, data mining and confirmatory statistical techniques in order to categorise different sub-groups of gamblers, with the explicit motivation of identifying problem gambling behaviours and reporting on the challenges and lessons learned from our case study.We demonstrate how techniques from various disciplines can be combined in order to gain insight into the behavioural patterns exhibited by different types of gamblers, as well as provide assurances of the correctness of our approach and findings. A highlight of this case study is both the methodology which demonstrates how such a combination of techniques provides a rich set of effective tools to undertake an exploratory and open-ended data analysis project that is guided by the process cube concept, as well as the findings themselves which indicate that the contribution that problem gamblers make to the total volume, expenditure, and revenue is higher than previous studies have maintained.

  17. Upon Further Review: V. An Examination of Previous Lightcurve Analysis from the Palmer Divide Observatory

    Science.gov (United States)

    Warner, Brian D.

    2011-01-01

    Updated results are given for nine asteroids previously reported from the Palmer Divide Observatory (PDO). The original images were re-measured to obtain new data sets using the latest version of MPO Canopus photometry software, analysis tools, and revised techniques for linking multiple observing runs covering several days to several weeks. Results that were previously not reported or were moderately different were found for 1659 Punkajarju, 1719 Jens, 1987 Kaplan, 2105 Gudy, 2961 Katsurahama, 3285 Ruth Wolfe, 3447 Burckhalter, 7816 Hanoi, and (34817) 2000 SE116. This is one in a series of papers that will examine results obtained during the initial years of the asteroid lightcurve program at PDO.

  18. Evaluation of conformal radiotherapy techniques through physics and biologic criteria

    International Nuclear Information System (INIS)

    Bloch, Jonatas Carrero

    2012-01-01

    In the fight against cancer, different irradiation techniques have been developed based on technological advances and aiming to optimize the elimination of tumor cells with the lowest damage to healthy tissues. The radiotherapy planning goal is to establish irradiation technical parameters in order to achieve the prescribed dose distribution over the treatment volumes. While dose prescription is based on radiosensitivity of the irradiated tissues, the physical calculations on treatment planning take into account dosimetric parameters related to the radiation beam and the physical characteristics of the irradiated tissues. To incorporate tissue's radiosensitivity into radiotherapy planning calculations can help particularize treatments and establish criteria to compare and elect radiation techniques, contributing to the tumor control and the success of the treatment. Accordingly, biological models of cellular response to radiation have to be well established. This work aimed to study the applicability of using biological models in radiotherapy planning calculations to aid evaluating radiotherapy techniques. Tumor control probability (TCP) was studied for two formulations of the linear-quadratic model, with and without repopulation, as a function of planning parameters, as dose per fraction, and of radiobiological parameters, as the α/β ratio. Besides, the usage of biological criteria to compare radiotherapy techniques was tested using a prostate planning simulated with Monte Carlo code PENELOPE. Afterwards, prostate planning for five patients from the Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto, USP, using three different techniques were compared using the tumor control probability. In that order, dose matrices from the XiO treatment planning system were converted to TCP distributions and TCP-volume histograms. The studies performed allow the conclusions that radiobiological parameters can significantly influence tumor control

  19. Mobile depth profiling and sub-surface imaging techniques for historical paintings—A review

    Energy Technology Data Exchange (ETDEWEB)

    Alfeld, Matthias, E-mail: matthias.alfeld@desy.de [University of Hamburg, Department of Chemistry, Martin-Luther-King Platz 6, D-20146 Hamburg (Germany); University of Antwerp, Department of Chemistry, Groenenbrogerlaan 171, B-2020 Antwerp (Belgium); Broekaert, José A.C., E-mail: jose.broekaert@chemie.uni-hamburg.de [University of Hamburg, Department of Chemistry, Martin-Luther-King Platz 6, D-20146 Hamburg (Germany)

    2013-10-01

    Hidden, sub-surface paint layers and features contain valuable information for the art-historical investigation of a painting's past and for its conservation for coming generations. The number of techniques available for the study of these features has been considerably extended in the last decades and established techniques have been refined. This review focuses on mobile non-destructive subsurface imaging and depth profiling techniques, which allow for the in-situ investigation of easel paintings, i.e. paintings on a portable support. Among the techniques discussed are: X-ray radiography and infrared reflectography, which are long established methods and are in use for several decades. Their capabilities of element/species specific imaging have been extended by the introduction of energy/wavelength resolved measurements. Scanning macro-X-ray fluorescence analysis made it for the first time possible to acquire elemental distribution images in-situ and optical coherence tomography allows for the non-destructive study the surface paint layers in virtual cross-sections. These techniques and their variants are presented next to other techniques, such as Terahertz imaging, Nuclear Magnetic Resonance depth profiling and established techniques for non destructive testing (thermography, ultrasonic imaging and laser based interference methods) applied in the conservation of historical paintings. Next to selected case studies the capabilities and limitations of the techniques are discussed. - Highlights: • All mobile sub-surface and depth-profiling techniques for paintings are reviewed. • The number of techniques available has increased considerably in the last years. • X-ray radiography and infrared reflectography are still the most used techniques. • Scanning macro-XRF and optical coherence tomography begin to establish. • Industrial non destructive testing techniques support the preservation of paintings.

  20. ANALYSIS OF THE POSSIBILITY FOR ESTABLISHING PROJECT MANAGEMENT OFFICE (PMO IN COMPANIES IN SERBIA

    Directory of Open Access Journals (Sweden)

    Dragana Milin

    2012-09-01

    Full Text Available Project Management Office (PMO is an organizational unit established to help project managers, project teams and the various levels of management in carrying out the principles of project management. The research was carried out in Serbia, in 2011, with the aim to establish which methodologies and techniques are used for project m anagement, and which of them are used the most frequently. Furthermore, the need for establishment of PMOs in Serbia is discussed. These offices should help in establishing a standardized methodology (at the organization level and thus overcome the obviou s poor use of any project management methodology at all.

  1. New continuous air pumping technique to improve clinical outcomes of descemet-stripping automated endothelial keratoplasty in asian patients with previous ahmed glaucoma valve implantation.

    Directory of Open Access Journals (Sweden)

    Chang-Min Liang

    Full Text Available BACKGROUND: To evaluate the outcomes of Descemet-stripping automated endothelial keratoplasty (DSAEK with the use of continuous air pumping technique in Asian eyes with previous Ahmed glaucoma valve implantation. METHODS: The DSAEK procedure was modified in that complete air retention of the anterior chamber was maintained for 10 min using continuous air pumping at 30 mm Hg. The primary outcome measurement was graft survival, and postoperative clinical features including, rate of graft detachment, endothelial cell count, intraocular pressure (IOP, surgical time and cup/disc ratio were also recorded. RESULTS: A total of 13 eyes of 13 patients which underwent modified DSAEK and 6 eyes of 6 patients which underwent conventional DSAEK were included. There was a significant difference in graft survival curves between two groups (P = 0.029; the 1-year graft survival rates were estimated as 100% and 66.7% for patients with modified DSAEK and those with traditional DSAEK, respectively. The rate of graft detachment were 0% and 33.3% for the modified DSAEK and conventional DSAEK groups, respectively (P = 0.088. The significantly lowered surgical time for air tamponade was noted in the modified DSAEK group compared to that in the conventional DSAEK group [median (IQR: 10.0 (10.0, 10.0 min vs. 24.5 (22.0, 27.0 min; P<0.001] Postoperatively, patients in the modified DSAEK group had significantly lower IOP as compared to the conventional DSAEK group [12.0 (11.0, 15.0 mm Hg vs. 16.0 (15.0, 18.0 mm Hg; P = 0.047]. Modified DSAEK patients had higher endothelial cell counts as compared to conventional DSAEK patients [2148.0 (1964.0, 2218.0 vs. 1529.0 (713.0, 2014.0], but the difference did not reach statistical significance (P = 0.072. CONCLUSIONS: New continuous air pumping technique in DSAEK can be performed safely and effectively in patients with prior GDDs placement who have corneal failure.

  2. Establishing reliable good initial quantum efficiency and in-situ laser cleaning for the copper cathodes in the RF gun

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, F., E-mail: zhoufeng@slac.stanford.edu; Sheppard, J.C.; Vecchione, T.; Jongewaard, E.; Brachmann, A.; Corbett, J.; Gilevich, S.; Weathersby, S.

    2015-05-21

    Establishing good initial quantum efficiency (QE) and reliable in-situ cleaning for copper cathode in the RF gun is of critical importance for the RF gun operations. Recent studies on the SLAC RF gun test bed indicated that the pre-cleaning (plasma cleaning) in the test chamber followed by copper cathode exposure to air for cathode change leads to a very low initial QE in the RF gun, and also demonstrated that without the pre-cleaning good initial QE >4×10{sup −5} can be routinely achieved in the RF gun with the cathodes of QE <1×10{sup −7} measured in the test chamber. QE can decay over the time in the RF gun. The in-situ laser cleaning technique for copper cathodes in the RF gun is established and refined in comparison to previous cleaning at the linac coherent light source, resulting in an improved QE and emittance evolutions. The physics of the laser cleaning process is discussed. It is believed that the reflectivity change is one of the major factors for the QE boost with the laser cleaning.

  3. Intralesional Osteophyte Regrowth Following Autologous Chondrocyte Implantation after Previous Treatment with Marrow Stimulation Technique.

    Science.gov (United States)

    Demange, Marco Kawamura; Minas, Tom; von Keudell, Arvind; Sodha, Sonal; Bryant, Tim; Gomoll, Andreas H

    2017-04-01

    Objective Bone marrow stimulation surgeries are frequent in the treatment of cartilage lesions. Autologous chondrocyte implantation (ACI) may be performed after failed microfracture surgery. Alterations to subchondral bone as intralesional osteophytes are commonly seen after previous microfracture and removed during ACI. There have been no reports on potential recurrence. Our purpose was to evaluate the incidence of intralesional osteophyte development in 2 cohorts: existing intralesional osteophytes and without intralesional osteophytes at the time of ACI. Study Design We identified 87 patients (157 lesions) with intralesional osteophytes among a cohort of 497 ACI patients. Osteophyte regrowth was analyzed on magnetic resonance imaging and categorized as small or large (less or more than 50% of the cartilage thickness). Twenty patients (24 defects) without intralesional osteophytes at the time of ACI acted as control. Results Osteophyte regrowth was observed in 39.5% of lesions (34.4% of small osteophytes and 5.1% of large osteophytes). In subgroup analyses, regrowth was observed in 45.8% of periosteal-covered defects and in 18.9% of collagen membrane-covered defects. Large osteophyte regrowth occurred in less than 5% in either group. Periosteal defects showed a significantly higher incidence for regrowth of small osteophytes. In the control group, intralesional osteophytes developed in 16.7% of the lesions. Conclusions Even though intralesional osteophytes may regrow after removal during ACI, most of them are small. Small osteophyte regrowth occurs almost twice in periosteum-covered ACI. Large osteophytes occur only in 5% of patients. Intralesional osteophyte formation is not significantly different in preexisting intralesional osteophytes and control groups.

  4. Preoperative screening: value of previous tests.

    Science.gov (United States)

    Macpherson, D S; Snow, R; Lofgren, R P

    1990-12-15

    To determine the frequency of tests done in the year before elective surgery that might substitute for preoperative screening tests and to determine the frequency of test results that change from a normal value to a value likely to alter perioperative management. Retrospective cohort analysis of computerized laboratory data (complete blood count, sodium, potassium, and creatinine levels, prothrombin time, and partial thromboplastin time). Urban tertiary care Veterans Affairs Hospital. Consecutive sample of 1109 patients who had elective surgery in 1988. At admission, 7549 preoperative tests were done, 47% of which duplicated tests performed in the previous year. Of 3096 previous results that were normal as defined by hospital reference range and done closest to the time of but before admission (median interval, 2 months), 13 (0.4%; 95% CI, 0.2% to 0.7%), repeat values were outside a range considered acceptable for surgery. Most of the abnormalities were predictable from the patient's history, and most were not noted in the medical record. Of 461 previous tests that were abnormal, 78 (17%; CI, 13% to 20%) repeat values at admission were outside a range considered acceptable for surgery (P less than 0.001, frequency of clinically important abnormalities of patients with normal previous results with those with abnormal previous results). Physicians evaluating patients preoperatively could safely substitute the previous test results analyzed in this study for preoperative screening tests if the previous tests are normal and no obvious indication for retesting is present.

  5. Proteomics Analysis Reveals Previously Uncharacterized Virulence Factors in Vibrio proteolyticus

    Directory of Open Access Journals (Sweden)

    Ann Ray

    2016-07-01

    Full Text Available Members of the genus Vibrio include many pathogens of humans and marine animals that share genetic information via horizontal gene transfer. Hence, the Vibrio pan-genome carries the potential to establish new pathogenic strains by sharing virulence determinants, many of which have yet to be characterized. Here, we investigated the virulence properties of Vibrio proteolyticus, a Gram-negative marine bacterium previously identified as part of the Vibrio consortium isolated from diseased corals. We found that V. proteolyticus causes actin cytoskeleton rearrangements followed by cell lysis in HeLa cells in a contact-independent manner. In search of the responsible virulence factor involved, we determined the V. proteolyticus secretome. This proteomics approach revealed various putative virulence factors, including active type VI secretion systems and effectors with virulence toxin domains; however, these type VI secretion systems were not responsible for the observed cytotoxic effects. Further examination of the V. proteolyticus secretome led us to hypothesize and subsequently demonstrate that a secreted hemolysin, belonging to a previously uncharacterized clan of the leukocidin superfamily, was the toxin responsible for the V. proteolyticus-mediated cytotoxicity in both HeLa cells and macrophages. Clearly, there remains an armory of yet-to-be-discovered virulence factors in the Vibrio pan-genome that will undoubtedly provide a wealth of knowledge on how a pathogen can manipulate host cells.

  6. Genetic modifications of established varieties of potato through mutagenesis

    International Nuclear Information System (INIS)

    Brown, C.R.

    1984-01-01

    Owing to the high intercrossability of improved clones with primitive cultivars and many wild species there is little justification for use of induced mutations in potato to increase variability per se. Modification of certain traits while leaving the genotype basically intact is a promising use of mutagenesis in potato. The successful curing of defects in clones will depend on the establishment a priori of three principles. First, the clones undergoing mutagenesis should be well established varieties tolerant or resistant to the major biotic and abiotic stresses in the area of cultivation. The yield and culinary quality should also be considered high. Second, there should exist some indication that the variation desired is induceable, either through reports of natural intra-clone variation or previous mutagenesis studies. Third, initial screening should be done in virus-free materials

  7. Iridoids as chemical markers of false ipecac (Ronabea emetica), a previously confused medicinal plant.

    Science.gov (United States)

    Berger, Andreas; Fasshuber, Hannes; Schinnerl, Johann; Robien, Wolfgang; Brecker, Lothar; Valant-Vetschera, Karin

    2011-12-08

    Several roots or rhizomes of rubiaceous species are reportedly used as the emetic and antiamoebic drug ipecac. True ipecac (Carapichea ipecacuanha) is chemically well characterized, in contrast to striated or false ipecac derived from the rhizomes of Ronabea emetica (syn. Psychotria emetica). Besides its previous use as substitute of ipecac, the latter species is applied in traditional medicine of Panama and fruits of its relative Ronabea latifolia are reported as curare additives from Colombia. Compounds of Ronabea emetica were isolated using standard chromatographic techniques, and structurally characterized by NMR spectroscopy and mass spectrometry. Organ specific distribution in Ronabea emetica as well as in Ronabea latifolia was further assessed by comparative HPLC analysis. Four iridoid-glucosides, asperuloside (1), 6α-hydroxygeniposide (2), deacetylasperulosidic acid (3) and asperulosidic acid (4) were extracted from leaves of Ronabea emetica. Rhizomes, used in traditional medicine, were dominated by 3. HPLC profiles of Ronabea latifolia were largely corresponding. These results contrast to the general tendency of producing emetine-type and indole alkaloids in species of Psychotria and closely related genera and merit chemotaxonomic significance, characterizing the newly delimited genus Ronabea. The aim of the work was to resolve the historic problem of adulteration of ipecac by establishing the chemical profile of Ronabea emetica, the false ipecac, as one of its less known sources. The paper demonstrates that different sources of ipecac can be distinguished by their phytochemistry, thus contributing to identifying adulterations of true ipecac. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  8. Studies on Plant Population and Stand Establishment Techniques for Increasing Productivity of Rice in Dera Ismail Khan, Pakistan

    Directory of Open Access Journals (Sweden)

    Mohammad Safdar BALOCH

    2007-06-01

    Full Text Available Rice production in Pakistan is constraint by many factors pertaining to prevalent planting techniques. A research on the feasibility of new planting techniques (direct seeding on flat, transplanting on flat, direct seeding on ridges, transplanting on ridges and parachute planting in transplanted and direct wet-seeded rice was undertaken at Dera Ismail Khan region of Pakistan's North West Frontier Province during 2002 and 2003. Among the planting techniques, the best performance for the yield formation and economic evaluation was noted for transplanting on flat during both years. Chinese parachute planting technology also showed very promising results in most of the parameters. Direct seeding on ridges could not excel transplanting on flat and parachute planting during both cropping seasons. The findings concluded the feasibility of parachute planting technology along with traditional rice transplanting on flat over all other planting techniques being practiced in the area.

  9. Information Requirements Specification II: Brainstorming Collective Decision-Making Technique.

    Science.gov (United States)

    Telem, Moshe

    1988-01-01

    Information requirements specification (IRS) constitutes an Achilles heel in the system life cycle of management information systems. This article establishes a systematic overall IRS technique applicable to organizations of all types and sizes. The technique's integration of brainstorming and theory Z principles creates an effective, stimulating,…

  10. Returning succession to downy brome dominated rangelands: roadblocks to perennial grass establishment

    Science.gov (United States)

    The most common cause of successional retrogression in the Great Basin is wildfires fueled by downy brome (Bromus tectorum). Downy brome invasion has reduced fire intervals from an estimated 60-100 years down to 5-10 years. Our previous research found that establishment of long-lived perennial grass...

  11. Microscale Shock Wave Physics Using Photonic Driver Techniques; TOPICAL

    International Nuclear Information System (INIS)

    SETCHELL, ROBERT E.; TROTT, WAYNE M.; CASTANEDA, JAIME N.; FARNSWORTH JR.,A. V.; BERRY, DANTE M.

    2002-01-01

    This report summarizes a multiyear effort to establish a new capability for determining dynamic material properties. By utilizing a significant reduction in experimental length and time scales, this new capability addresses both the high per-experiment costs of current methods and the inability of these methods to characterize materials having very small dimensions. Possible applications include bulk-processed materials with minimal dimensions, very scarce or hazardous materials, and materials that can only be made with microscale dimensions. Based on earlier work to develop laser-based techniques for detonating explosives, the current study examined the laser acceleration, or photonic driving, of small metal discs (''flyers'') that can generate controlled, planar shockwaves in test materials upon impact. Sub-nanosecond interferometric diagnostics were developed previously to examine the motion and impact of laser-driven flyers. To address a broad range of materials and stress states, photonic driving levels must be scaled up considerably from the levels used in earlier studies. Higher driving levels, however, increase concerns over laser-induced damage in optics and excessive heating of laser-accelerated materials. Sufficiently high levels require custom beam-shaping optics to ensure planar acceleration of flyers. The present study involved the development and evaluation of photonic driving systems at two driving levels, numerical simulations of flyer acceleration and impact using the CTH hydrodynamics code, design and fabrication of launch assemblies, improvements in diagnostic instrumentation, and validation experiments on both bulk and thin-film materials having well-established shock properties. The primary conclusion is that photonic driving techniques are viable additions to the methods currently used to obtain dynamic material properties. Improvements in launch conditions and diagnostics can certainly be made, but the main challenge to future applications

  12. Field-based detection of biological samples for forensic analysis: Established techniques, novel tools, and future innovations.

    Science.gov (United States)

    Morrison, Jack; Watts, Giles; Hobbs, Glyn; Dawnay, Nick

    2018-04-01

    Field based forensic tests commonly provide information on the presence and identity of biological stains and can also support the identification of species. Such information can support downstream processing of forensic samples and generate rapid intelligence. These approaches have traditionally used chemical and immunological techniques to elicit the result but some are known to suffer from a lack of specificity and sensitivity. The last 10 years has seen the development of field-based genetic profiling systems, with specific focus on moving the mainstay of forensic genetic analysis, namely STR profiling, out of the laboratory and into the hands of the non-laboratory user. In doing so it is now possible for enforcement officers to generate a crime scene DNA profile which can then be matched to a reference or database profile. The introduction of these novel genetic platforms also allows for further development of new molecular assays aimed at answering the more traditional questions relating to body fluid identity and species detection. The current drive for field-based molecular tools is in response to the needs of the criminal justice system and enforcement agencies, and promises a step-change in how forensic evidence is processed. However, the adoption of such systems by the law enforcement community does not represent a new strategy in the way forensic science has integrated previous novel approaches. Nor do they automatically represent a threat to the quality control and assurance practices that are central to the field. This review examines the historical need and subsequent research and developmental breakthroughs in field-based forensic analysis over the past two decades with particular focus on genetic methods Emerging technologies from a range of scientific fields that have potential applications in forensic analysis at the crime scene are identified and associated issues that arise from the shift from laboratory into operational field use are discussed

  13. Comparison of a fluoroquinolone surface plasmon resonance biosensor screening assay with established methods

    NARCIS (Netherlands)

    Weigel, S.; Pikkemaat, M.G.; Elferink, J.W.A.; Mulder, P.P.J.; Huet, A.C.; Delahaut, P.; Schittko, S.; Flerus, R.; Nielen, M.W.F.

    2009-01-01

    The performance of a previously developed immunochemical biosensor screening method for fluoroquinolone (FQ) antibiotics in poultry muscle, fish and egg was compared with established methods. Blank sample material of the target matrices was individually spiked with the FQs at half maximum residue

  14. A comparison of morbidity associated with placenta previa with and without previous caesarean sections

    International Nuclear Information System (INIS)

    Baqai, S.; Siraj, A.; Noor, N.

    2018-01-01

    To compare the morbidity associated with placenta previa with and without previous caesarean sections. Study Design: Retrospective comparative study. Place and Duration of Study: From March 2014 till March 2016 in the department of Obstetrics and Gynaecology at PNS Shifa hospital Karachi. Material and Methods: After the approval from hospital ethical committee, antenatal patients with singleton pregnancy of gestational age >32 weeks, in the age group of 20-40 years diagnosed to have placenta previa included in the study. All patients with twin pregnancy less than 20 years and more than 40 years of age were excluded. The records of all patients fulfilling the inclusion criteria were reviewed. Data had been collected for demographic and maternal variables, placenta previa, history of previous lower segment caesarean section (LSCS), complications associated with placenta previa and techniques used to control blood loss were recorded. Results: During the study period, 6879 patients were delivered in PNS Shifa, out of these, 2060 (29.9%) had caesarean section out of these, 47.3% patients had previous history of LSCS. Thirty three (1.6%) patients were diagnosed to have placenta previa and frequency of placenta previa was significantly higher in patients with previous history of LSCS than previous normal delivery of LSCS i.e. 22 vs. 11 (p=0.023). It was observed that the frequency of morbidly adherent placenta (MAP) and Intensive care unit (ICU) stay were significantly higher in patients with previous history of LSCS than previous history of normal delivery. Conclusion: Frequency of placenta previa was significantly higher in patients with history of LSCS. Also placenta previa remains a major risk factor for various maternal complications. (author)

  15. Biogeography of Wood-Boring Crustaceans (Isopoda: Limnoriidae) Established in European Coastal Waters

    Science.gov (United States)

    Borges, Luísa M. S.; Merckelbach, Lucas M.; Cragg, Simon M.

    2014-01-01

    Marine wood-borers of the Limnoriidae cause great destruction to wooden structures exposed in the marine environment. In this study we collated occurrence data obtained from field surveys, spanning over a period of 10 years, and from an extensive literature review. We aimed to determine which wood-boring limnoriid species are established in European coastal waters; to map their past and recent distribution in Europe in order to infer species range extension or contraction; to determine species environmental requirements using climatic envelopes. Of the six species of wood-boring Limnoria previously reported occurring in Europe, only Limnoria lignorum, L. quadripunctata and L. tripunctata are established in European coastal waters. L. carinata and L. tuberculata have uncertain established status, whereas L. borealis is not established in European waters. The species with the widest distribution in Europe is Limnoria lignorum, which is also the most tolerant species to a range of salinities. L. quadripunctata and L. tripunctata appear to be stenohaline. However, the present study shows that both L. quadripunctata and L. tripunctata are more widespread in Europe than previous reports suggested. Both species have been found occurring in Europe since they were described, and their increased distribution is probably the results of a range expansion. On the other hand L. lignorum appears to be retreating poleward with ocean warming. In certain areas (e.g. southern England, and southern Portugal), limnoriids appear to be very abundant and their activity is rivalling that of teredinids. Therefore, it is important to monitor the distribution and destructive activity of these organisms in Europe. PMID:25313796

  16. Development of food preservation and processing techniques by radiation

    Energy Technology Data Exchange (ETDEWEB)

    Byun, Myung Woo; Lee, Ju Woon; Kim, Dong Ho [KAERI, Taejon (Korea, Republic of); Yook, Hong Sun [Chungnam National Univ., Taejon (Korea, Republic of); Kim, Hak Soo [Sogang Univ., Seoul (Korea, Republic of); Lee, Cherl Ho; Park, Hyun Jin [Korea Univ., Seoul (Korea, Republic of); Kang, Il Jun [Hallym Univ., Chuncheon (Korea, Republic of); Kwon, Jung Ho [Kyungbook National Univ., Taegu (Korea, Republic of)

    2002-05-01

    To secure national food resources, development of energy-saving food processing and preservation technologies, establishment of method on improvement of national health and safety by development of alternative techniques of chemicals and foundation of the production of hygienic food and public health related products by irradiation technology were studied. Results at current stage are following; Processing techniques of low salted and fermented fish using gamma irradiation were developed and superiority of using irradiation to conventional food processing methods was established. Processing technique of value-added functional materials for the manufacture of food or public health products using RT/BT/NT combination technology was developed. The basic theories for the technology development to reduce toxic or undesirable compounds in food such as allergy or carcinogens were established. Exterminating methods of quarantine organisms in herbs/spices was established and the quality evaluation and detection conditions in quarantine treatment were set. From the studies on 'program of public understanding' based on safety of the gamma irradiated food, the information for public relation in enlargement of consumer acceptance/implementation and the peaceful use of nuclear energy were secured. Results from the research project will contribute on improvement of competency of domestic food industry and export market. The results also expect the improvement of public health by prevention of food borne diseases and enhancement of national economy and industry by increase of direct/indirect productivity.

  17. Development of food preservation and processing techniques by radiation

    International Nuclear Information System (INIS)

    Byun, Myung Woo; Lee, Ju Woon; Kim, Dong Ho; Yook, Hong Sun; Kim, Hak Soo; Lee, Cherl Ho; Park, Hyun Jin; Kang, Il Jun; Kwon, Jung Ho

    2002-05-01

    To secure national food resources, development of energy-saving food processing and preservation technologies, establishment of method on improvement of national health and safety by development of alternative techniques of chemicals and foundation of the production of hygienic food and public health related products by irradiation technology were studied. Results at current stage are following; Processing techniques of low salted and fermented fish using gamma irradiation were developed and superiority of using irradiation to conventional food processing methods was established. Processing technique of value-added functional materials for the manufacture of food or public health products using RT/BT/NT combination technology was developed. The basic theories for the technology development to reduce toxic or undesirable compounds in food such as allergy or carcinogens were established. Exterminating methods of quarantine organisms in herbs/spices was established and the quality evaluation and detection conditions in quarantine treatment were set. From the studies on 'program of public understanding' based on safety of the gamma irradiated food, the information for public relation in enlargement of consumer acceptance/implementation and the peaceful use of nuclear energy were secured. Results from the research project will contribute on improvement of competency of domestic food industry and export market. The results also expect the improvement of public health by prevention of food borne diseases and enhancement of national economy and industry by increase of direct/indirect productivity

  18. Development and Establishment of Detection Method of Irradiated Foods

    International Nuclear Information System (INIS)

    Byun, Myung Woo; Lee, Ju Woon; Kim, Dong Ho; Jo, Cheo Run; Kim, Jang Ho; Kim, Kyong Su

    2004-12-01

    The present project was related to the development and establishment of the detection techniques for the safety management of gamma-irradiated food and particularly conducted for the establishment of standard detection method for gamma-irradiated dried spices and raw materials, dried meat and fish powder for processed foods, bean paste powder, red pepper paste powder, soy sauce powder, and starch for flavoring ingredients described in 3, 6, 7 section of Korean Food Standard. Since the approvement of gamma-irradiated food items will be enlarged due to the international tendency for gamma-irradiated food, it was concluded that the establishment of detailed detection methods for each food group is not efficient for the enactment and enforcement of related regulations. For this reason, in order to establish the standard detection method, a detection system for gamma-irradiated food suitable for domestic operation was studied using comparative analysis of domestic and foreign research data classified by items and methods and European Standard as a reference. According to the comparative analyses of domestic and foreign research data and regulations of detection for gamma-irradiated food, it was concluded to be desirable that the optimal detection method should be decided after principal detection tests such as physical, chemical, and biological detection methods are established as standard methods and that the specific descriptions such as pre-treatment of raw materials, test methods, and the evaluation of results should be separately prescribed

  19. Development and Establishment of Detection Method of Irradiated Foods

    Energy Technology Data Exchange (ETDEWEB)

    Byun, Myung Woo; Lee, Ju Woon; Kim, Dong Ho; Jo, Cheo Run; Kim, Jang Ho; Kim, Kyong Su

    2004-12-15

    The present project was related to the development and establishment of the detection techniques for the safety management of gamma-irradiated food and particularly conducted for the establishment of standard detection method for gamma-irradiated dried spices and raw materials, dried meat and fish powder for processed foods, bean paste powder, red pepper paste powder, soy sauce powder, and starch for flavoring ingredients described in 3, 6, 7 section of Korean Food Standard. Since the approvement of gamma-irradiated food items will be enlarged due to the international tendency for gamma-irradiated food, it was concluded that the establishment of detailed detection methods for each food group is not efficient for the enactment and enforcement of related regulations. For this reason, in order to establish the standard detection method, a detection system for gamma-irradiated food suitable for domestic operation was studied using comparative analysis of domestic and foreign research data classified by items and methods and European Standard as a reference. According to the comparative analyses of domestic and foreign research data and regulations of detection for gamma-irradiated food, it was concluded to be desirable that the optimal detection method should be decided after principal detection tests such as physical, chemical, and biological detection methods are established as standard methods and that the specific descriptions such as pre-treatment of raw materials, test methods, and the evaluation of results should be separately prescribed.

  20. Indiana pouch continent urinary reservoir in patients with previous pelvic irradiation

    International Nuclear Information System (INIS)

    Mannel, R.S.; Braly, P.S.; Buller, R.E.

    1990-01-01

    Little information exists on the use of continent urinary reservoirs in patients with previous pelvic irradiation. We report the use of the Indiana pouch urinary reservoir in ten women with a history of pelvic irradiation for cervical cancer, of whom eight underwent a total pelvic exenteration for recurrent pelvic tumor and two had diversion for radiation-induced vesicovaginal fistula. All ten women achieved daytime continence, with a median time between catheterizations of 4.5 hours and a median pouch capacity of 500 mL. There was no evidence of leakage from the reservoir or significant ureteral reflux or obstruction on postoperative radiographic evaluation. No patient has required reoperation or had significant postoperative complications with the technique described

  1. Left ventricular assist device implantation in a patient who had previously undergone apical myectomy for hypertrophic cardiomyopathy.

    Science.gov (United States)

    Cho, Yang Hyun; Deo, Salil V; Topilsky, Yan; Grogan, Martha A; Park, Soon J

    2012-03-01

    Apical hypertrophy is a rare variant of hypertropic cardiomyopathy. These patients may present with end-stage congestive heart failure subsequent to long standing diastolic dysfunction. We report the technique for left ventricular assist device insertion in a patient with previous apical myectomy for hypertrophic cardiomyopathy. © 2012 Wiley Periodicals, Inc.

  2. Mercury bioaccumulation and elimination by Xenomelanires brasiliensis - radioactive tracers technique

    International Nuclear Information System (INIS)

    Malagrino, Waldir; Mesquita, Carlos Henrique de; Sousa, Eduinetty Ceci P.M. de

    2002-01-01

    The present work has as main objective to emphasized the importance of using radioactive tracers as well as to establish a methodology for the utilization of 203 Hg in the bioaccumulation study of mercury by X enomelanires brasiliensis. The exposure time was 168 hours. The bioaccumulation of mercury from the water as well as the elimination of the metal previously absorbed were determined by measuring the activity of 203 Hg, which was added to the water in the beginning of the experiments. The technique chosen is suitable to study the behavior of the stable mercury since the radioisotope used is an isotope of the same element and therefore presents the same chemical properties. The results obtained show that the absorption and elimination of mercury by Xenomelanires brasiliensis is slow, 168 hours being necessary for the elimination of 38 % of the previously absorbed mercury. The results are of main concern if it is considered that the literature about bioaccumulation of mercury by the Brazilian ichthyofauna is scarce. Furthermore the species Xenomelanires brasiliensis is part of the food chain and the results can be used in the evaluation of the potential risk of the mercury bioaccumulation by fishes of higher trophic levels and by men who are the final link of the food chain. (author)

  3. Huffman-based code compression techniques for embedded processors

    KAUST Repository

    Bonny, Mohamed Talal

    2010-09-01

    The size of embedded software is increasing at a rapid pace. It is often challenging and time consuming to fit an amount of required software functionality within a given hardware resource budget. Code compression is a means to alleviate the problem by providing substantial savings in terms of code size. In this article we introduce a novel and efficient hardware-supported compression technique that is based on Huffman Coding. Our technique reduces the size of the generated decoding table, which takes a large portion of the memory. It combines our previous techniques, Instruction Splitting Technique and Instruction Re-encoding Technique into new one called Combined Compression Technique to improve the final compression ratio by taking advantage of both previous techniques. The instruction Splitting Technique is instruction set architecture (ISA)-independent. It splits the instructions into portions of varying size (called patterns) before Huffman coding is applied. This technique improves the final compression ratio by more than 20% compared to other known schemes based on Huffman Coding. The average compression ratios achieved using this technique are 48% and 50% for ARM and MIPS, respectively. The Instruction Re-encoding Technique is ISA-dependent. It investigates the benefits of reencoding unused bits (we call them reencodable bits) in the instruction format for a specific application to improve the compression ratio. Reencoding those bits can reduce the size of decoding tables by up to 40%. Using this technique, we improve the final compression ratios in comparison to the first technique to 46% and 45% for ARM and MIPS, respectively (including all overhead that incurs). The Combined Compression Technique improves the compression ratio to 45% and 42% for ARM and MIPS, respectively. In our compression technique, we have conducted evaluations using a representative set of applications and we have applied each technique to two major embedded processor architectures

  4. Report of the first research co-ordination meeting on the co-ordinated research programme: Development and selection of analytical techniques for measuring accidentally released radionuclides in environment

    International Nuclear Information System (INIS)

    2001-01-01

    The participants at the second Research Co-ordination Meeting (Vienna, 12-16 August 1991) of the CRP on 'Rapid Instrumental and Separation Methods for Monitoring Radionuclides in Food and Environmental Samples', recommended that a new CRP be established. The current CRP on 'Development and Selection of Analytical Techniques and Procedures for Measuring Accidentally Released Radionuclides in Environment' was established based on this recommendation. The objectives of this CRP are to conduct research and development on applicable methodologies for response to accidental releases, and to improve and maintain the capabilities of the network of laboratories and provide training of individuals within member states. Thus, the CRP serves as a vehicle to maintain contact within the network of laboratories, while developing and transferring analytical techniques and procedures for measuring accidentally released radioactivity. The purpose of the Research Co-ordination Meeting is to discuss the proposed research programs, the status to date and the work planned for the duration of the CRP. The meeting also provides the opportunity for the CRP participants to exchange ideas and possibly develop collaborations in their research. The members of the CRP also need to discuss issues related to the previous CRP on Rapid methods. These include: the preparation of the final report of the previous CRP, the preparation of an addendum to TRS-295 and the ultimate revision or updating of TRS-295. Finally, it is intended that the members of the CRP should discuss the mandate and scope of work of the network of analytical laboratories and the steps needed to firmly establish this network

  5. [Effect of previous experience in reacting to a danger signal on "open field" behavior in the rat].

    Science.gov (United States)

    Poltyreva, T E; Petrov, E S

    1983-01-01

    Modification of rats behaviour in an "hopen field" test was investigated, induced by an acoustic stimulus, previously subjected to conditioning in a shuttle chamber in experiments with possibility and impossibility of avoidance from electrical shock. It has been established that presentation of a stimulus having the meaning of a danger signal, in a new situation, significantly suppresses investigating behaviour of rats, whereas the stimulus which had not been subjected to conditioning exerts no marked effect on behaviour. The greatest suppression was observed in rats with "learned helplessness". This fact suggests that the degree of suppression of the behaviour in an open field in response to a danger signal, depends on the animal's previous experience in reacting to this signal.

  6. Establishment of trees and shrubs on lands disturbed by mining in the West

    Science.gov (United States)

    Ardell J. Bjugstad

    1984-01-01

    Increased research and development of cultural practices and species has assured success of establishment of trees and shrubs on lands disturbed by surface mining. Trickle irrigation and water harvesting techniques have increased survival of planted stock by 250 percent for some species.

  7. Mediastinal involvement in lymphangiomatosis: a previously unreported MRI sign

    Energy Technology Data Exchange (ETDEWEB)

    Shah, Vikas; Shah, Sachit; Barnacle, Alex; McHugh, Kieran [Great Ormond Street Hospital for Children, Department of Radiology, London (United Kingdom); Sebire, Neil J. [Great Ormond Street Hospital for Children, Department of Histopathology, London (United Kingdom); Brock, Penelope [Great Ormond Street Hospital for Children, Department of Oncology, London (United Kingdom); Harper, John I. [Great Ormond Street Hospital for Children, Department of Dermatology, London (United Kingdom)

    2011-08-15

    Multifocal lymphangiomatosis is a rare systemic disorder affecting children. Due to its rarity and wide spectrum of clinical, histological and imaging features, establishing the diagnosis of multifocal lymphangiomatosis can be challenging. The purpose of this study was to describe a new imaging sign in this disorder: paraspinal soft tissue and signal abnormality at MRI. We retrospectively reviewed the imaging, clinical and histopathological findings in a cohort of eight children with thoracic involvement from this condition. Evidence of paraspinal chest disease was identified at MRI and CT in all eight of these children. The changes comprise heterogeneous intermediate-to-high signal parallel to the thoracic vertebrae on T2-weighted sequences at MRI, with abnormal paraspinal soft tissue at CT and plain radiography. Multifocal lymphangiomatosis is a rare disorder with a broad range of clinicopathological and imaging features. MRI allows complete evaluation of disease extent without the use of ionising radiation and has allowed us to describe a previously unreported imaging sign in this disorder, namely, heterogeneous hyperintense signal in abnormal paraspinal tissue on T2-weighted images. (orig.)

  8. Establishment of primary bovine intestinal epithelial cell culture and clone method.

    Science.gov (United States)

    Zhan, Kang; Lin, Miao; Liu, Ming-Mei; Sui, Yang-Nan; Zhao, Guo-Qi

    2017-01-01

    The aim of this study was to establish bovine intestinal epithelial cell (BIEC) line and provide a novel clone cell method. Although various strategies of bovine cell culture and clone techniques have been reported, these methods remain not established. Here, we culture successfully primary BIECs and establish a novel clone cell method. Our result showed that BIECs could be successfully cultured and passaged about generation 5. These cellular aggregates and clusters were adherent loosely at day 2 of culture. Cell aggregates and clusters start to proliferate after approximately 4 d. The BIECs showed positive reaction against cytokeratin 18, E-cadherin, and characteristics of epithelial-like morphology. In addition, the fatty acid-binding proteins (FABPs), villin, and intestinal peptidase (IP) band were positive in BIECs. Our results suggest that the establishment of culturing and clone BIEC methods will apply to isolate and clone other primary cells. These BIECs could therefore contribute to the study of bovine intestinal nutrient absorption and regulation, immune regulation, and the pathogenesis of the bovine intestinal disease, which will provide intestinal cell model in vitro.

  9. Large sample neutron activation analysis: establishment at CDTN/CNEN, Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Menezes, Maria Angela de B.C., E-mail: menezes@cdtn.b [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil); Jacimovic, Radojko, E-mail: radojko.jacimovic@ijs.s [Jozef Stefan Institute, Ljubljana (Slovenia). Dept. of Environmental Sciences. Group for Radiochemistry and Radioecology

    2011-07-01

    In order to improve the application of the neutron activation technique at CDTN/CNEN, the large sample instrumental neutron activation analysis is being established, IAEA BRA 14798 and FAPEMIG APQ-01259-09 projects. This procedure, LS-INAA, usually requires special facilities for the activation as well as for the detection. However, the TRIGA Mark I IPR R1, CDTN/CNEN has not been adapted for the irradiation and the usual gamma spectrometry has being carried out. To start the establishment of the LS-INAA, a 5g sample - IAEA/Soil 7 reference material was analyzed by k{sub 0}-standardized method. This paper is about the detector efficiency over the volume source using KayWin v2.23 and ANGLE V3.0 software. (author)

  10. The low-frequency sound power measuring technique for an underwater source in a non-anechoic tank

    Science.gov (United States)

    Zhang, Yi-Ming; Tang, Rui; Li, Qi; Shang, Da-Jing

    2018-03-01

    In order to determine the radiated sound power of an underwater source below the Schroeder cut-off frequency in a non-anechoic tank, a low-frequency extension measuring technique is proposed. This technique is based on a unique relationship between the transmission characteristics of the enclosed field and those of the free field, which can be obtained as a correction term based on previous measurements of a known simple source. The radiated sound power of an unknown underwater source in the free field can thereby be obtained accurately from measurements in a non-anechoic tank. To verify the validity of the proposed technique, a mathematical model of the enclosed field is established using normal-mode theory, and the relationship between the transmission characteristics of the enclosed and free fields is obtained. The radiated sound power of an underwater transducer source is tested in a glass tank using the proposed low-frequency extension measuring technique. Compared with the free field, the radiated sound power level of the narrowband spectrum deviation is found to be less than 3 dB, and the 1/3 octave spectrum deviation is found to be less than 1 dB. The proposed testing technique can be used not only to extend the low-frequency applications of non-anechoic tanks, but also for measurement of radiated sound power from complicated sources in non-anechoic tanks.

  11. 76 FR 45553 - Agency Information Collection Activities: Proposed Collection; Comment Request; Establishing No...

    Science.gov (United States)

    2011-07-29

    ... collection of information, submit or view public comments, access the index listing of the contents of the... appropriate automated electronic, mechanical, or other technological collection techniques or other forms of... potentially affected by this action are state, local, and Tribal governments. Title: Establishing No-Discharge...

  12. Perioperative Intravascular Fluid Assessment and Monitoring: A Narrative Review of Established and Emerging Techniques

    Directory of Open Access Journals (Sweden)

    Sumit Singh

    2011-01-01

    Full Text Available Accurate assessments of intravascular fluid status are an essential part of perioperative care and necessary in the management of the hemodynamically unstable patient. Goal-directed fluid management can facilitate resuscitation of the hypovolemic patient, reduce the risk of fluid overload, reduce the risk of the injudicious use of vasopressors and inotropes, and improve clinical outcomes. In this paper, we discuss the strengths and limitations of a spectrum of noninvasive and invasive techniques for assessing and monitoring intravascular volume status and fluid responsiveness in the perioperative and critically ill patient.

  13. A second study of the prediction of cognitive errors using the 'CREAM' technique

    International Nuclear Information System (INIS)

    Collier, Steve; Andresen, Gisle

    2000-03-01

    Some human errors, such as errors of commission and knowledge-based errors, are not adequately modelled in probabilistic safety assessments. Even qualitative methods for handling these sorts of errors are comparatively underdeveloped. The 'Cognitive Reliability and Error Analysis Method' (CREAM) was recently developed for prediction of cognitive error modes. It has not yet been comprehensively established how reliable, valid and generally useful it could be to researchers and practitioners. A previous study of CREAM at Halden was promising, showing a relationship between errors predicted in advance and those that actually occurred in simulated fault scenarios. The present study continues this work. CREAM was used to make predictions of cognitive error modes throughout two rather difficult fault scenarios. Predictions were made of the most likely cognitive error mode, were one to occur at all, at several points throughout the expected scenarios, based upon the scenario design and description. Each scenario was then run 15 times with different operators. Error modes occurring during simulations were later scored using the task description for the scenario, videotapes of operator actions, eye-track recording, operators' verbal protocols and an expert's concurrent commentary. The scoring team had no previous substantive knowledge of the experiment or the techniques used, so as to provide a more stringent test of the data and knowledge needed for scoring. The scored error modes were then compared with the CREAM predictions to assess the degree of agreement. Some cognitive error modes were predicted successfully, but the results were generally not so encouraging as the previous study. Several problems were found with both the CREAM technique and the data needed to complete the analysis. It was felt that further development was needed before this kind of analysis can be reliable and valid, either in a research setting or as a practitioner's tool in a safety assessment

  14. Parental Attitudes Toward Advanced Behavior Guidance Techniques Used in Pediatric Dentistry.

    Science.gov (United States)

    Patel, Monica; McTigue, Dennis J; Thikkurissy, Sarat; Fields, Henry W

    2016-01-01

    To re-examine parental attitudes toward advanced behavior management techniques in pediatric dentistry and determine whether cost, urgency, and amount of treatment influence parental preferences. Parents viewed previously validated videotaped clinical vignettes of four advanced behavior guidance techniques: (1) passive immobilization; (2) active immobilization; (3) general anesthesia; and (4) oral sedation. The study was conducted in a children's hospital dental clinic and a suburban private pediatric dentistry office. Parents rated overall acceptance of the techniques, and acceptance under specified conditions using an anchored visual analogue scale. One hundred five parents completed the survey; 55 from the children's hospital and 50 from private practice. Oral sedation was rated as the most acceptable technique, followed by general anesthesia, active immobilization, and passive immobilization. As urgency, convenience, and previous experience increased, parental acceptance of the technique increased. As cost of treatment increased, parental acceptance decreased. Ratings between the children's hospital group and private practice group differed, as did the demographic variables of insurance, income, and race. The hierarchy of parental acceptance of advanced behavior guidance techniques is changing with increasing approval of pharmacological management and decreasing approval of physical management. The health care delivery system, urgency, convenience, previous experience, and cost all influence parental acceptance.

  15. Magnetoencephalography: Fundamentals and Established and Emerging Clinical Applications in Radiology

    International Nuclear Information System (INIS)

    Braeutigam, Sven

    2013-01-01

    Magnetoencephalography is a noninvasive, fast, and patient friendly technique for recording brain activity. It is increasingly available and is regarded as one of the most modern imaging tools available to radiologists. The dominant clinical use of this technology currently centers on two, partly overlapping areas, namely, localizing the regions from which epileptic seizures originate, and identifying regions of normal brain function in patients preparing to undergo brain surgery. As a consequence, many radiologists may not yet be familiar with this technique. This review provides an introduction to magnetoencephalography, discusses relevant analytical techniques, and presents recent developments in established and emerging clinical applications such as pervasive developmental disorders. Although the role of magnetoencephalography in diagnosis, prognosis, and patient treatment is still limited, it is argued that this technology is exquisitely capable of contributing indispensable information about brain dynamics not easily obtained with other modalities. This, it is believed, will make this technology an important clinical tool for a wide range of disorders in the future

  16. Comparison of different retreatment techniques and root canal sealers: a scanning electron microscopic study

    Directory of Open Access Journals (Sweden)

    Neslihan Simsek

    2014-05-01

    Full Text Available The aim of this study was to evaluate the effectiveness of two retreatment techniques, in terms of the operating time and scanning electron microscopy (SEM results, in removing three different root canal sealers from root canals that were previously filled with gutta-percha. Sixty extracted single-rooted human premolars were divided into three groups and filled with iRoot SP, MM Seal, and AH Plus sealers, along with gutta-percha, through a lateral compaction technique. Root canal fillings of the samples were removed by ESI ultrasonic tips or R-Endo files. The time to reach the working length was recorded. Longitudinally sectioned samples were examined under SEM magnification. Each picture was evaluated in terms of the residual debris. Data were statistically analyzed with the Kruskall-Wallis test. No statistically significant differences were found in terms of operating time (p>0.05. Significant differences in the number of debris-free dentinal tubules were found among the root canal thirds, but this finding was not influenced by the experimental group (p < 0.05. Resin sealer tags were observed inside the dentinal tubules in the MM Seal group. Under the conditions of this study, it may be established that there was no difference among the sealers and retreatment techniques.

  17. Biopsy techniques for intraocular tumors

    Directory of Open Access Journals (Sweden)

    Pukhraj Rishi

    2016-01-01

    Full Text Available Biopsy involves the surgical removal of a tissue specimen for histopathologic evaluation. Most intraocular tumors are reliably diagnosed based on the clinical evaluation or with noninvasive diagnostic techniques. However, accurately diagnosing a small percentage of tumors can be challenging. A tissue biopsy is thus needed to establish a definitive diagnosis and plan the requisite treatment. From fine-needle aspiration biopsy (FNAB to surgical excision, all tissue collection techniques have been studied in the literature. Each technique has its indications and limitations. FNAB has been reported to provide for 88-95% reliable and safe ophthalmic tumor diagnosis and has gained popularity for prognostic purposes and providing eye conserving treatment surgeries. The technique and instrumentation for biopsy vary depending upon the tissue involved (retina, choroid, subretinal space, vitreous, and aqueous, suspected diagnosis, size, location, associated retinal detachment, and clarity of the media. The cytopathologist confers a very important role in diagnosis and their assistance plays a key role in managing and planning the treatment for malignancies.

  18. Development of food preservation and processing techniques by radiation

    Energy Technology Data Exchange (ETDEWEB)

    Byun, Myung Woo; Lee, Ju Woon; Kim, Dong Ho [KAERI, Taejon (Korea, Republic of); Yook, Hong Sun [Chungnam National Univ., Taejon (Korea, Republic of); Kim, Hak Soo [Sogang Univ., Seoul (Korea, Republic of); Lee, Cherl Ho; Park, Hyun Jin [Korea Univ., Seoul (Korea, Republic of); Kang, Il Jun [Hallym Univ., Chuncheon (Korea, Republic of); Kwon, Jung Ho [Kyungbook National Univ., Taegu (Korea, Republic of)

    2002-05-01

    To secure national food resources, development of energy-saving food processing and preservation technologies, establishment of method on improvement of national health and safety by development of alternative techniques of chemicals and foundation of the production of hygienic food and public health related products by irradiation technology were studied. Results at current stage are following; Processing techniques of low salted and fermented fish using gamma irradiation were developed and superiority of using irradiation to conventional food processing methods was established. Processing technique of value-added functional materials for the manufacture of food or public health products using RT/BT/NT combination technology was developed. The basic theories for the technology development to reduce toxic or undesirable compounds in food such as allergy or carcinogens were established. Exterminating methods of quarantine organisms in herbs/spices was established and the quality evaluation and detection conditions in quarantine treatment were set. From the studies on 'program of public understanding' based on safety of the gamma irradiated food, the information for public relation in enlargement of consumer acceptance/implementation and the peaceful use of nuclear energy were secured. Results from the research project will contribute on improvement of competency of domestic food industry and export market. The results also expect the improvement of public health by prevention of food borne diseases and enhancement of national economy and industry by increase of direct/indirect productivity.

  19. SONOGRAPHIC PREDICTION OF SCAR DEHISCENCE IN WOMEN WITH PREVIOUS CAESAREAN SECTION

    Directory of Open Access Journals (Sweden)

    Shubhada Suhas Jajoo

    2018-01-01

    Full Text Available BACKGROUND Caesarean section (Sectio Caesarea is a surgical method for the completion of delivery. After various historical modifications of operative techniques, modern approach consists in the transverse dissection of the anterior wall of the uterus. The rate of vaginal birth after caesarean section was significantly reduced from year to year and the rate of repeated caesarean section is increased during the past 10 years. Evaluation of scar thickness is done by ultrasound, but it is still debatable size of thick scar that would be guiding “cut-off value” for the completion of the delivery method. To better assess the risk of uterine rupture, some authors have proposed sonographic measurement of lower uterine segment thickness near term assuming that there is an inverse correlation between LUS thickness and the risk of uterine scar defect. Therefore, this assessment for the management of women with prior CS may increase safety during labour by selecting women with the lowest risk of uterine rupture. The aim of the study is to study the diagnostic accuracy of sonographic measurements of the Lower Uterine Segment (LUS thickness near term in predicting uterine scar defects in women with prior Caesarean Section (CS. We aim to ascertain the best cut-off values for predicting uterine rupture. MATERIALS AND METHODS 100 antenatal women with history of previous one LSCS who come to attend antenatal clinic will be assessed for scar thickness by transabdominal ultrasonography and its correlation with intraoperative findings. This prospective longitudinal study was conducted for 1 year after IEC approval with inclusion criteria previous one LSCS. Exclusion criteria- 1 Previous myomectomy scar; 2 Previous 2 LSCS; 3 Previous hysterotomy scar. RESULTS Our findings indicate that there is a strong association between degree of LUS thinning measured near term and the risk of uterine scar defect at birth. In our study, optimal cut-off value for predicting

  20. A Secure Key Establishment Protocol for ZigBee Wireless Sensor Networks

    DEFF Research Database (Denmark)

    Yuksel, Ender; Nielson, Hanne Riis; Nielson, Flemming

    2009-01-01

    ZigBee is a wireless sensor network standard that defines network and application layers on top of IEEE 802.15.4’s physical and medium access control layers. In the latest version of ZigBee, enhancements are prescribed for the security sublayer but we show in this paper that problems persist....... In particular we show that the End-to-End Application Key Establishment Protocol is flawed and we propose a secure protocol instead. We do so by using formal verification techniques based on static program analysis and process algebras. We present a way of using formal methods in wireless network security......, and propose a secure key establishment protocol for ZigBee networks....

  1. Chemical vapor deposition: A technique for applying protective coatings

    Energy Technology Data Exchange (ETDEWEB)

    Wallace, T.C. Sr.; Bowman, M.G.

    1979-01-01

    Chemical vapor deposition is discussed as a technique for applying coatings for materials protection in energy systems. The fundamentals of the process are emphasized in order to establish a basis for understanding the relative advantages and limitations of the technique. Several examples of the successful application of CVD coating are described. 31 refs., and 18 figs.

  2. Comparison of survey techniques on detection of northern flying squirrels

    Science.gov (United States)

    Diggins, Corinne A.; Gilley, L. Michelle; Kelly, Christine A.; Ford, W. Mark

    2016-01-01

    The ability to detect a species is central to the success of monitoring for conservation and management purposes, especially if the species is rare or endangered. Traditional methods, such as live capture, can be labor-intensive, invasive, and produce low detection rates. Technological advances and new approaches provide opportunities to more effectively survey for species both in terms of accuracy and efficiency than previous methods. We conducted a pilot comparison study of a traditional technique (live-trapping) and 2 novel noninvasive techniques (camera-trapping and ultrasonic acoustic surveys) on detection rates of the federally endangered Carolina northern flying squirrel (Glaucomys sabrinus coloratus) in occupied habitat within the Roan Mountain Highlands of North Carolina, USA. In 2015, we established 3 5 × 5 live-trapping grids (6.5 ha) with 4 camera traps and 4 acoustic detectors systematically embedded in each grid. All 3 techniques were used simultaneously during 2 4-day survey periods. We compared techniques by assessing probability of detection (POD), latency to detection (LTD; i.e., no. of survey nights until initial detection), and survey effort. Acoustics had the greatest POD (0.37 ± 0.06 SE), followed by camera traps (0.30 ± 0.06) and live traps (0.01 ± 0.005). Acoustics had a lower LTD than camera traps (P = 0.017), where average LTD was 1.5 nights for acoustics and 3.25 nights for camera traps. Total field effort was greatest with live traps (111.9 hr) followed by acoustics (8.4 hr) and camera traps (9.6 hr), although processing and examination for data of noninvasive techniques made overall effort similar among the 3 methods. This pilot study demonstrated that both noninvasive methods were better rapid-assessment detection techniques for flying squirrels than live traps. However, determining seasonal effects between survey techniques and further development of protocols for both noninvasive techniques is

  3. Optimal technique of linear accelerator–based stereotactic radiosurgery for tumors adjacent to brainstem

    International Nuclear Information System (INIS)

    Chang, Chiou-Shiung; Hwang, Jing-Min; Tai, Po-An; Chang, You-Kang; Wang, Yu-Nong; Shih, Rompin; Chuang, Keh-Shih

    2016-01-01

    Stereotactic radiosurgery (SRS) is a well-established technique that is replacing whole-brain irradiation in the treatment of intracranial lesions, which leads to better preservation of brain functions, and therefore a better quality of life for the patient. There are several available forms of linear accelerator (LINAC)–based SRS, and the goal of the present study is to identify which of these techniques is best (as evaluated by dosimetric outcomes statistically) when the target is located adjacent to brainstem. We collected the records of 17 patients with lesions close to the brainstem who had previously been treated with single-fraction radiosurgery. In all, 5 different lesion catalogs were collected, and the patients were divided into 2 distance groups—1 consisting of 7 patients with a target-to-brainstem distance of less than 0.5 cm, and the other of 10 patients with a target-to-brainstem distance of ≥ 0.5 and < 1 cm. Comparison was then made among the following 3 types of LINAC-based radiosurgery: dynamic conformal arcs (DCA), intensity-modulated radiosurgery (IMRS), and volumetric modulated arc radiotherapy (VMAT). All techniques included multiple noncoplanar beams or arcs with or without intensity-modulated delivery. The volume of gross tumor volume (GTV) ranged from 0.2 cm 3 to 21.9 cm 3 . Regarding the dose homogeneity index (HI ICRU ) and conformity index (CI ICRU ) were without significant difference between techniques statistically. However, the average CI ICRU = 1.09 ± 0.56 achieved by VMAT was the best of the 3 techniques. Moreover, notable improvement in gradient index (GI) was observed when VMAT was used (0.74 ± 0.13), and this result was significantly better than those achieved by the 2 other techniques (p < 0.05). For V 4 Gy of brainstem, both VMAT (2.5%) and IMRS (2.7%) were significantly lower than DCA (4.9%), both at the p < 0.05 level. Regarding V 2 Gy of normal brain, VMAT plans had attained 6.4 ± 5%; this was significantly better

  4. Establishment of prairies

    International Nuclear Information System (INIS)

    Lotero Cadavid, J.

    2001-01-01

    Are analyzed the establishment of prairies, such as the selection of the species, the factors of the environment, the impact in the establishment and forage production and its relation to the soil, the precipitation, the temperature, the light and the biotic factors. It is indicated that the selection of the species to settle down, is directly related with the climate and the soil and they group to be tolerant to drought, tolerant to flood soils, tolerant to humid soils, tolerant to soils very acids, moderately acids and saline. It is noticed that a bad establishment of the grasses can be due to the bad quality of the seed, a temperature and unfavorable humidity can cause low germination; equally seeds planted very deeply in heavy soils with excess of humidity. Considerations are made about the establishment and growth of the prairies in connection with the germination, cultures, sowing density and sowing on time, as well as for the soil preparation, the sowing in terrestrial mechanic and non mechanic and the use of cultivations forms of low cost and fertilization systems; equally the establishment of leguminous in mixture with gramineous, the renovation of prairies and the establishment of pastures

  5. Evaluation of miniature tension specimen fabrication techniques and performance

    International Nuclear Information System (INIS)

    Hamilton, M.L.; Blotter, M.A.; Edwards, D.J.

    1993-01-01

    The confident application of miniature tensile specimens requires adequate control over their fabrication and is facilitated by automated test and analysis techniques. Three fabrication processes -- punching, chemical milling, and electrical discharge machining (EDM) -- were recently evaluated, leading to the replacement of the previously used punching technique with a wire EDM technique. The automated data acquisition system was upgraded, and an interactive data analysis program was developed

  6. Evaluation of miniature tensile specimen fabrication techniques and performance

    Energy Technology Data Exchange (ETDEWEB)

    Hamilton, M.L. (Pacific Northwest Lab., Richland, WA (United States)); Blotter, M.A.; Edwards, D.J. (Missouri Univ., Rolla, MO (United States))

    1992-01-01

    The confident application of miniature tensile specimens requires adequate control over their fabrication and is facilitated by automated test and analysis techniques. Three fabrication processes -- punching, chemical, milling, and electrical discharge machining (EDM) -- were recently evaluated, leading to the replacement of the previously used punching technique with a wire EDM technique. The automated data acquisition system was upgraded, and an interactive data analysis program was developed.

  7. Evaluation of miniature tensile specimen fabrication techniques and performance

    International Nuclear Information System (INIS)

    Hamilton, M.L.; Blotter, M.A.; Edwards, D.J.

    1992-01-01

    The confident application of miniature tensile specimens requires adequate control over their fabrication and is facilitated by automated test and analysis techniques. Three fabrication processes -- punching, chemical, milling, and electrical discharge machining (EDM) -- were recently evaluated, leading to the replacement of the previously used punching technique with a wire EDM technique. The automated data acquisition system was upgraded, and an interactive data analysis program was developed

  8. Ultrasound-assisted extraction technique for establishing selenium contents in breast cancer biopsies by Zeeman-electrothermal atomic absorption spectrometry using multi-injection

    International Nuclear Information System (INIS)

    Lavilla, I.; Mosquera, A.; Millos, J.; Cameselle, J.; Bendicho, C.

    2006-01-01

    A solid-liquid extraction method is developed to establish the contents of selenium in breast cancer biopsies. The method is based on the ultrasound-assisted extraction of selenium from pretreated biopsies prior to Se determination by atomic absorption spectrometry with longitudinal-Zeeman background correction. Fifty-one breast biopsies were collected from the Cies Hospital (Vigo, Spain), 32 of which correspond to tumor tissue and 19 to normal tissue (parenchyma). Difficulties arising from the samples analyzed, i.e. small samples mass (50-100 mg), extremely low Se contents and sample texture modification including tissue hardening due to formaldehyde preservation are addressed and overcome. High intensity sonication using a probe together with addition of hydrogen peroxide succeeded in completely extracting Se from biopsies. The multiple injection technique was useful to tackle the low Se contents present in some biopsies. The detection limit was 25 ng g -1 of Se and the precision, expressed as relative standard deviation, was less than 10%. Se contents ranged from 0.08 to 0.4 μg g -1 for parenchyma samples and from 0.09 to 0.8 μg g -1 for tumor samples. In general, Se levels in tumor biopsies were higher as compared with the adjacent normal tissue in 19 patients by a factor of up to 6. Analytical data confirmed Se accumulation in the breast tumors

  9. Establishment of reproducible osteosarcoma rat model using orthotopic implantation technique.

    Science.gov (United States)

    Yu, Zhe; Sun, Honghui; Fan, Qingyu; Long, Hua; Yang, Tongtao; Ma, Bao'an

    2009-05-01

    In experimental musculoskeletal oncology, there remains a need for animal models that can be used to assess the efficacy of new and innovative treatment methodologies for bone tumors. Rat plays a very important role in the bone field especially in the evaluation of metabolic bone diseases. The objective of this study was to develop a rat osteosarcoma model for evaluation of new surgical and molecular methods of treatment for extremity sarcoma. One hundred male SD rats weighing 125.45+/-8.19 g were divided into 5 groups and anesthetized intraperitoneally with 10% chloral hydrate. Orthotopic implantation models of rat osteosarcoma were performed by injecting directly into the SD rat femur with a needle for inoculation with SD tumor cells. In the first step of the experiment, 2x10(5) to 1x10(6) UMR106 cells in 50 microl were injected intraosseously into median or distal part of the femoral shaft and the tumor take rate was determined. The second stage consisted of determining tumor volume, correlating findings from ultrasound with findings from necropsia and determining time of survival. In the third stage, the orthotopically implanted tumors and lung nodules were resected entirely, sectioned, and then counter stained with hematoxylin and eosin for histopathologic evaluation. The tumor take rate was 100% for implants with 8x10(5) tumor cells or more, which was much less than the amount required for subcutaneous implantation, with a high lung metastasis rate of 93.0%. Ultrasound and necropsia findings matched closely (r=0.942; p<0.01), which demonstrated that Doppler ultrasonography is a convenient and reliable technique for measuring cancer at any stage. Tumor growth curve showed that orthotopically implanted tumors expanded vigorously with time-lapse, especially in the first 3 weeks. The median time of survival was 38 days and surgical mortality was 0%. The UMR106 cell line has strong carcinogenic capability and high lung metastasis frequency. The present rat

  10. Models and Techniques for Proving Data Structure Lower Bounds

    DEFF Research Database (Denmark)

    Larsen, Kasper Green

    In this dissertation, we present a number of new techniques and tools for proving lower bounds on the operational time of data structures. These techniques provide new lines of attack for proving lower bounds in both the cell probe model, the group model, the pointer machine model and the I...... bound of tutq = (lgd􀀀1 n). For ball range searching, we get a lower bound of tutq = (n1􀀀1=d). The highest previous lower bound proved in the group model does not exceed ((lg n= lg lg n)2) on the maximum of tu and tq. Finally, we present a new technique for proving lower bounds....../O-model. In all cases, we push the frontiers further by proving lower bounds higher than what could possibly be proved using previously known techniques. For the cell probe model, our results have the following consequences: The rst (lg n) query time lower bound for linear space static data structures...

  11. Saudi dental hygienists' opinions regarding establishing a professional association.

    Science.gov (United States)

    Joufi, A I; Wilder, R S; Curran, A E; Brame, J L

    2018-02-28

    To assess the opinions of dental hygienists in Saudi Arabia regarding the establishment of a professional association including the role it should have to meet their professional needs. A cross-sectional electronic survey using Qualtrics was utilized. IRB exemption was obtained prior to distribution. Although there are 298 licensed Saudi dental hygienists in Saudi Arabia, email addresses were only available for 101 respondents: those obtained previously by direct contact for the purpose of initiation of a professional association and those referred by the direct contacts. Subjects were emailed a link to the survey. Seventy-seven subjects responded fully to the survey yielding a response rate of 70.3%. Most 91.5% (n = 65) of the respondents favoured the establishment of a Saudi dental hygiene professional association. Eighty-eight per cent (n = 59) responded that such an association would promote development of the profession in the country at least somewhat and 86.6% (n = 58) agreed that their professional needs could be met by its establishment. Interestingly, half of those who did not support the creation of the professional association believed it would promote development of the profession and meet professional needs. A representative sample of dental hygienists in Saudi Arabia support the establishment of a professional association and feel that it would advocate and promote the dental hygiene profession in the country and meet their professional needs. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  12. Comparative study of the legal status of NGOs in Iran and France: from the establishment to work

    Directory of Open Access Journals (Sweden)

    Mohammad Hossein Ramazani Ghavamabadi

    2015-12-01

    Full Text Available THE NGOs one of the most important -state actors. For this to compile useful organizations the state regulations regarding established and codified their activity. This study sought to explain the issue and established barter their activities in two Iranian legal system and France. In Iranian legal system regulations in the founded and barter their activity there is in comparison with France legal system a bit tough. supervision previous in establishment time and supervision next previous after the foundation and all activities are subjects in this study compared to that between the two legal system under study. One of the most prominent works of the identified legal personality for this organization are the case. The new penal trial Iran inspired by the French Penal procedure law a step forward in support of the presence of the barter their punishment in the process. What is important is the codification of legal about cathedral establishment of this organization are derived from the experience of the other legal system legal system including the French so that through this the presence and activities of these organizations in the fields of different facilitation.

  13. Techniques of forest restoration in restingas

    Directory of Open Access Journals (Sweden)

    Liliane Garcia da Silva Morais Rodrigues

    2016-03-01

    Full Text Available Restinga is an ecosystem of the Atlantic Forest Biome vegetation which has ecological functions and is undergoing anthropogenic occupations that result in the disturbance and its suppression of these environments. But to be the restoration of degraded restinga is necessary to know the different formations of the ecosystem and their respective characteristics. From this diagnosis, one can choose the most appropriate techniques to apply for its restoration. Thus, this study aims to conduct a literature on restoration techniques in restinga environments. It was found that forest restoration on restinga, in most cases there is use of natural regeneration techniques nucleation, and these studies highlight the successional advances and establishments of life forms preserved features of the area, thus making the restoration in these environments.

  14. New technique of uterine body carcinoma brachytherapy. Pt. 1. Radium chain

    Energy Technology Data Exchange (ETDEWEB)

    Rattka, P.; Jedrus, S. (Instytut Onkologii, Gliwice (Poland))

    1980-01-01

    A simple technique of uterine cavity tamponade with radium charges arranged in a chain has been evolved, establishing at the same time an optimal dose on the basis of computer calculations. Own experiences with the use of this technique in 31 patients are presented.

  15. An anonymization technique using intersected decision trees

    Directory of Open Access Journals (Sweden)

    Sam Fletcher

    2015-07-01

    Full Text Available Data mining plays an important role in analyzing the massive amount of data collected in today’s world. However, due to the public’s rising awareness of privacy and lack of trust in organizations, suitable Privacy Preserving Data Mining (PPDM techniques have become vital. A PPDM technique provides individual privacy while allowing useful data mining. We present a novel noise addition technique called Forest Framework, two novel data quality evaluation techniques called EDUDS and EDUSC, and a security evaluation technique called SERS. Forest Framework builds a decision forest from a dataset and preserves all the patterns (logic rules of the forest while adding noise to the dataset. We compare Forest Framework to its predecessor, Framework, and another established technique, GADP. Our comparison is done using our three evaluation criteria, as well as Prediction Accuracy. Our experimental results demonstrate the success of our proposed extensions to Framework and the usefulness of our evaluation criteria.

  16. Fourwing saltbrush establishment in the Keating Uniform Shrub Garden—first year results.

    Science.gov (United States)

    J. Michael Geist; Paul J. Edgerton

    1984-01-01

    Site preparation techniques to aid establishment of fourwing saltbush (Atriplex canescens) were compared at a test location in eastern Oregon. Survival and growth of transplanted seedlings were improved after one season of growth by either spot spraying with herbicides or scalping to reduce competing vegetation. Average growth of seedlings was...

  17. Establishing a good dentist-patient relationship: skills defined from the dental faculty perspective.

    Science.gov (United States)

    Orsini, Cesar A; Jerez, Oscar M

    2014-10-01

    The importance of developing good dentist-patient relationships has been well documented, but previous studies have focused on social techniques, not considering the psychological and behavioral characteristics of patients, and have used definitions and instruments that were not dental-specific. Therefore, the aims of this study were to propose a definition of dentist-patient relationship skills, derived from dental faculty members' criteria and informed by Emotional Intelligence concepts, and to propose a preliminary dental-specific, face-valid, and reliable self-assessment instrument. The study was conducted in three phases. Phases I and II defined dentist-patient relationship competence through literature analysis and semi-structured interviews with expert key informants, establishing the outcome skills. In Phase III, the instrument was constructed and piloted. Communication skills and basic psychological tools resulted in core topics for use in practice. The definition both specifies and broadens social interactions in dentistry by including dental faculty members' criteria and topics such as psychological tools and pre-, intra-, and postoperative topics appropriate for use during consultation, examination, and treatment. The instrument was found suitable, reasonable, and accessible with a Cronbach's alpha level of 0.95. Future studies are needed to confirm the definition, as well as the instrument's validity, reliability, transference, and sensitivity to the dental educational environment.

  18. Current role of endovascular therapy in Marfan patients with previous aortic surgery

    Directory of Open Access Journals (Sweden)

    Ibrahim Akin

    2008-02-01

    Full Text Available Ibrahim Akin, Stephan Kische, Tim C Rehders, Tushar Chatterjee, Henrik Schneider, Thomas Körber, Christoph A Nienaber, Hüseyin InceDepartment of Medicine, Division of Cardiology at the University Hospital Rostock, Rostock School of Medicine, Ernst-Heydemann-Str. 6, 18057 Rostock, GermanyAbstract: The Marfan syndrome is a heritable disorder of the connective tissue which affects the cardiovascular, ocular, and skeletal system. The cardiovascular manifestation with aortic root dilatation, aortic valve regurgitation, and aortic dissection has a prevalence of 60% to 90% and determines the premature death of these patients. Thirty-four percent of the patients with Marfan syndrome will have serious cardiovascular complications requiring surgery in the first 10 years after diagnosis. Before aortic surgery became available, the majority of the patients died by the age of 32 years. Introduction in the aortic surgery techniques caused an increase of the 10 year survival rate up to 97%. The purpose of this article is to give an overview about the feasibility and outcome of stent-graft placement in the descending thoracic aorta in Marfan patients with previous aortic surgery.Keywords: Marfan syndrome, aortic dissection, root replacement, stent-graft, previous aortic surgery

  19. Microscopy techniques in flavivirus research.

    Science.gov (United States)

    Chong, Mun Keat; Chua, Anthony Jin Shun; Tan, Terence Tze Tong; Tan, Suat Hoon; Ng, Mah Lee

    2014-04-01

    The Flavivirus genus is composed of many medically important viruses that cause high morbidity and mortality, which include Dengue and West Nile viruses. Various molecular and biochemical techniques have been developed in the endeavour to study flaviviruses. However, microscopy techniques still have irreplaceable roles in the identification of novel virus pathogens and characterization of morphological changes in virus-infected cells. Fluorescence microscopy contributes greatly in understanding the fundamental viral protein localizations and virus-host protein interactions during infection. Electron microscopy remains the gold standard for visualizing ultra-structural features of virus particles and infected cells. New imaging techniques and combinatory applications are continuously being developed to push the limit of resolution and extract more quantitative data. Currently, correlative live cell imaging and high resolution three-dimensional imaging have already been achieved through the tandem use of optical and electron microscopy in analyzing biological specimens. Microscopy techniques are also used to measure protein binding affinities and determine the mobility pattern of proteins in cells. This chapter will consolidate on the applications of various well-established microscopy techniques in flavivirus research, and discuss how recently developed microscopy techniques can potentially help advance our understanding in these membrane viruses. Copyright © 2013 Elsevier Ltd. All rights reserved.

  20. Systematic approach to establishing criticality biases

    International Nuclear Information System (INIS)

    Larson, S.L.

    1995-09-01

    A systematic approach has been developed to determine benchmark biases and apply those biases to code results to meet the requirements of DOE Order 5480.24 regarding documenting criticality safety margins. Previously, validation of the code against experimental benchmarks to prove reasonable agreement was sufficient. However, DOE Order 5480.24 requires contractors to adhere to the requirements of ANSI/ANS-8.1 and establish subcritical margins. A method was developed to incorporate biases and uncertainties from benchmark calculations into a k eff value with quantifiable uncertainty. The method produces a 95% confidence level in both the k eff value of the scenario modeled and the distribution of the k eff S calculated by the Monte Carlo code. Application of the method to a group of benchmarks modeled using the KENO-Va code and the SCALE 27 group cross sections is also presented

  1. Ground-based intercomparison of two isoprene measurement techniques

    Directory of Open Access Journals (Sweden)

    E. Leibrock

    2003-01-01

    Full Text Available An informal intercomparison of two isoprene (C5H8 measurement techniques was carried out during Fall of 1998 at a field site located approximately 3 km west of Boulder, Colorado, USA. A new chemical ionization mass spectrometric technique (CIMS was compared to a well-established gas chromatographic technique (GC. The CIMS technique utilized benzene cation chemistry to ionize isoprene. The isoprene levels measured by the CIMS were often larger than those obtained with the GC. The results indicate that the CIMS technique suffered from an anthropogenic interference associated with air masses from the Denver, CO metropolitan area as well as an additional interference occurring in clean conditions. However, the CIMS technique is also demonstrated to be sensitive and fast. Especially after introduction of a tandem mass spectrometric technique, it is therefore a candidate for isoprene measurements in remote environments near isoprene sources.

  2. Minilaparoscopic technique for inguinal hernia repair combining transabdominal pre-peritoneal and totally extraperitoneal approaches.

    Science.gov (United States)

    Carvalho, Gustavo L; Loureiro, Marcelo P; Bonin, Eduardo A; Claus, Christiano P; Silva, Frederico W; Cury, Antonio M; Fernandes, Flavio A M

    2012-01-01

    Endoscopic surgical repair of inguinal hernia is currently conducted using 2 techniques: the totally extraperitoneal (TEP) and the transabdominal (TAPP) hernia repair. The TEP procedure is technically advantageous, because of the use of no mesh fixation and the elimination of the peritoneal flap, leading to less postoperative pain and faster recovery. The drawback is that TEP is not performed as frequently, because of its complexity and longer learning curve. In this study, we propose a hybrid technique that could potentially become the gold standard of minimally invasive inguinal hernia surgery. This will be achieved by combining established advantages of TEP and TAPP associated with the precision and cosmetics of minilaparoscopy (MINI). Between January and July 2011, 22 patients were admitted for endoscopic inguinal hernia repair. The combined technique was initiated with TAPP inspection and direct visualization of a minilaparoscopic trocar dissection of the preperitoneum space. A10-mm trocar was then placed inside the previously dissected preperitoneal space, using the same umbilical TAPP skin incision. Minilaparoscopic retroperitoneal dissection was completed by TEP, and the surgical procedure was finalized with intraperitoneal review and correction of the preperitoneal work. The minilaparoscopic TEP-TAPP combined approach for inguinal hernia is feasible, safe, and allows a simple endoscopic repair. This is achieved by combining features and advantages of both TAPP and TEP techniques using precise and sophisticated MINI instruments. Minilaparoscopic preperitoneal dissection allows a faster and easier creation of the preperitoneal space for the TEP component of the procedure.

  3. Detour technique, Dipping technique, or IIeal bladder flap technique for surgical correction of uretero-ileal anastomotic stricture in orthotopic ileal neobladder

    Directory of Open Access Journals (Sweden)

    Mohamed Wishahi

    2015-08-01

    Full Text Available ABSTRACTBackground:Uretero-ileal anastomotic stricture (UIAS is a urological complication after ileal neobladder, the initial management being endourological intervention. If this fails or stricture recurs, surgical intervention will be indicated.Design and Participants:From 1994 to 2013, 129 patients were treated for UIAS after unsuccessful endourological intervention. Unilateral UIAS was present in 101 patients, and bilateral in 28 patients; total procedures were 157. The previous ileal neobladder techniques were Hautmann neobladder, detubularized U shape, or spherical shape neobladder.Surgical procedures:Dipping technique was performed in 74 UIAS. Detour technique was done in 60 renal units. Ileal Bladder flap was indicated in 23 renal units. Each procedure ended with insertion of double J, abdominal drain, and indwelling catheter.Results:Follow-up was done for 12 to 36 months. Patency of the anastomosis was found in 91.7 % of cases. Thirteen patients (8.3% underwent antegrade dilatation and insertion of double J.Conclusion:After endourological treatment for uretero-ileal anastomotic failure, basically three techniques may be indicated: dipping technique, detour technique, and ileal bladder flap. The indications are dependent on the length of the stenotic/dilated ureteral segment. Better results for long length of stenotic ureter are obtained with detour technique; for short length stenotic ureter dipping technique; when the stenotic segment is 5 cm or more with a short ureter, the ileal tube flap is indicated. The use of double J stent is mandatory in the majority of cases. Early intervention is the rule for protecting renal units from progressive loss of function.

  4. Endplug Welding Techniques developed for SFR Metallic Fuel Elements

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jung Won; Kim, Soo Sung; Woo, Yoon Myeng; Kim, Hyung Tae; Lee, Ho Jin; Kim, Ki Hwan [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2013-10-15

    In Korea, the R and D on SFR has been begun since 1997, as one of the national long-term nuclear R and D programs. The international collaborative research is under way on fuel developments within Advanced Fuel Project for Gen-IV SFR with the closed fuel cycle of full actinide recycling, while TRU bearing metallic fuel, U-TRU-Zr alloy fuel, was selected and is being developed. For the fabrication of SFR metallic fuel elements, the endplug welding is a crucial process. The sealing of endplug to cladding tube should be hermetically perfect to prevent a leakage of fission gases and to maintain a good reactor performance. In this study, the welding technique, welding equipment, welding conditions and parameters were developed to make SFR metallic fuel elements. The TIG welding technique was adopted and the welding joint design was developed. And the optimal welding conditions and parameters were also established. In order to make SFR metallic fuel elements, the welding technique, welding equipment, welding conditions and parameters were developed. The TIG welding technique was adopted and the welding joint design was developed. And the optimal welding conditions and parameters were also established.

  5. Endplug Welding Techniques developed for SFR Metallic Fuel Elements

    International Nuclear Information System (INIS)

    Lee, Jung Won; Kim, Soo Sung; Woo, Yoon Myeng; Kim, Hyung Tae; Lee, Ho Jin; Kim, Ki Hwan

    2013-01-01

    In Korea, the R and D on SFR has been begun since 1997, as one of the national long-term nuclear R and D programs. The international collaborative research is under way on fuel developments within Advanced Fuel Project for Gen-IV SFR with the closed fuel cycle of full actinide recycling, while TRU bearing metallic fuel, U-TRU-Zr alloy fuel, was selected and is being developed. For the fabrication of SFR metallic fuel elements, the endplug welding is a crucial process. The sealing of endplug to cladding tube should be hermetically perfect to prevent a leakage of fission gases and to maintain a good reactor performance. In this study, the welding technique, welding equipment, welding conditions and parameters were developed to make SFR metallic fuel elements. The TIG welding technique was adopted and the welding joint design was developed. And the optimal welding conditions and parameters were also established. In order to make SFR metallic fuel elements, the welding technique, welding equipment, welding conditions and parameters were developed. The TIG welding technique was adopted and the welding joint design was developed. And the optimal welding conditions and parameters were also established

  6. Establishment of the International Power Institute

    Energy Technology Data Exchange (ETDEWEB)

    Coles, Julius E.

    2000-04-29

    Building on the two previous trips to Central America last year, International Power Institute (IPI) and its partner Tennessee Valley Infrastructure Group (TVIG) have focused their attention this quarter on project sites in Honduras. TVIG's unit--an Integrated Infrastructure Platform or IIP--combines water and electricity production in a single integrated unit, thereby providing both products at a lower cost than could be attained for each one separately. Because of the unmet demand for clean drinking water and electricity in remote towns throughout the developing world, the need for such units is widespread. Previous visits to Honduras have resulted in strong in-country commercial interest, support in the form of memorandums of understanding by key government agencies, and identification of four prospective project sites for IIP installations. From March 5 to March 15 and with IPI support and participation, representatives from the TVIG, Tennessee Valley Authority (TVA), IPI, and market research firm International Business Initiatives (IBI) conducted an intensive survey of project opportunities in the four communities, to establish how IIPs might help these four communities enhance their economic development, A key aspect of the projects examined is the need to make them economically self-supporting so that they will be viable in the private sector. Summary of specific project site studies follow here, and feasibility studies for the four sites are included as attachments.

  7. Estimation of fracture parameters in foam core materials using thermal techniques

    DEFF Research Database (Denmark)

    Dulieu-Barton, J. M.; Berggreen, Christian; Boyenval Langlois, C.

    2010-01-01

    is described. A mode I simulated crack in the form of a machined notch is used to establish the feasibility of the TSA approach to derive stress intensity factors for the foam material. The overall goal is to demonstrate that thermal techniques have the ability to provide deeper insight into the behaviour......The paper presents some initial work on establishing the stress state at a crack tip in PVC foam material using a non-contact infra-red technique known as thermoelastic stress analysis (TSA). A parametric study of the factors that may affect the thermoelastic response of the foam material...

  8. Techniques for Liquid Rocket Combustion Spontaneous Stability and Rough Combustion Assessments

    Science.gov (United States)

    Kenny, R. J.; Giacomoni, C.; Casiano, M. J.; Fischbach, S. R.

    2016-01-01

    This work presents techniques for liquid rocket engine combustion stability assessments with respect to spontaneous stability and rough combustion. Techniques covering empirical parameter extraction, which were established in prior works, are applied for three additional programs: the F-1 Gas Generator (F1GG) component test program, the RS-84 preburner component test program, and the Marshall Integrated Test Rig (MITR) program. Stability assessment parameters from these programs are compared against prior established spontaneous stability metrics and updates are identified. Also, a procedure for comparing measured with predicted mode shapes is presented, based on an extension of the Modal Assurance Criterion (MAC).

  9. Restoration techniques for Sphagnum-dominated peatlands

    Energy Technology Data Exchange (ETDEWEB)

    Ferland, C.; Rochefort, L. [Laval University, Sainte-Foy, PQ (Canada). Department of Phytology

    1997-07-01

    After peat harvesting, peat mosses do not usually recolonize the abandoned site. The purpose of this study is to develop techniques for restoring peatlands. Sphagnum diaspores from natural peatlands were introduced to exploited peatlands. The influence of microrelief, of planting companion species with the Sphagnum, and of light phosphorus fertilization on establishment of a peat moss carpet are examined. The results show that Sphagnum diaspores can be reintroduced on bare peat surfaces. The restoration method is combined with techniques to improve substrata moisture conditions, such as creation of surface roughness and the use of companion plant species. 32 refs., 6 figs., 3 tabs.

  10. Synthesis of nano γ-alumina by the solvothermal technique

    International Nuclear Information System (INIS)

    Meor Yusoff Meor Sulaiman; Masliana Muslimin

    2006-01-01

    The paper describes work done on synthesis of γ-alumina by using the solvo thermal technique. Synthesis of γ-alumina involves the transition reactions of the aluminium hydroxide into alumina by a dehydroxylation process. As there are many forms of transition aluminas produced during this process, a x-ray diffraction (XRD) technique was used to identify γ-alumina and the other forms of alumina. After establishing the optimum conditions for the production of a single-phase γ-alumina, characteristic study on the product was performed. An important parameter in establishing nanosized powders is their crystallite size and analysis of the γ-alumina shows that it is a nanosized powder with a size of 28 nm. Other properties analysed include morphology, surface area and particle size. (Author)

  11. Prediction of UV spectra and UV-radiation damage in actual plasma etching processes using on-wafer monitoring technique

    International Nuclear Information System (INIS)

    Jinnai, Butsurin; Fukuda, Seiichi; Ohtake, Hiroto; Samukawa, Seiji

    2010-01-01

    UV radiation during plasma processing affects the surface of materials. Nevertheless, the interaction of UV photons with surface is not clearly understood because of the difficulty in monitoring photons during plasma processing. For this purpose, we have previously proposed an on-wafer monitoring technique for UV photons. For this study, using the combination of this on-wafer monitoring technique and a neural network, we established a relationship between the data obtained from the on-wafer monitoring technique and UV spectra. Also, we obtained absolute intensities of UV radiation by calibrating arbitrary units of UV intensity with a 126 nm excimer lamp. As a result, UV spectra and their absolute intensities could be predicted with the on-wafer monitoring. Furthermore, we developed a prediction system with the on-wafer monitoring technique to simulate UV-radiation damage in dielectric films during plasma etching. UV-induced damage in SiOC films was predicted in this study. Our prediction results of damage in SiOC films shows that UV spectra and their absolute intensities are the key cause of damage in SiOC films. In addition, UV-radiation damage in SiOC films strongly depends on the geometry of the etching structure. The on-wafer monitoring technique should be useful in understanding the interaction of UV radiation with surface and in optimizing plasma processing by controlling UV radiation.

  12. Automatic video segmentation employing object/camera modeling techniques

    NARCIS (Netherlands)

    Farin, D.S.

    2005-01-01

    Practically established video compression and storage techniques still process video sequences as rectangular images without further semantic structure. However, humans watching a video sequence immediately recognize acting objects as semantic units. This semantic object separation is currently not

  13. The state-of-the-art of the established conventional and advanced NDE-techniques and procedures for defect detection and sizing

    International Nuclear Information System (INIS)

    Crutzen, S.; Edelmann, X.

    1988-01-01

    This document presents several non-destructive ultrasonic techniques used for the inspection of various welds. Some probes are described and acoustic holography is presented as well as the time-of-flight diffraction (TOFD) technique. The three phases of the Programme for the Inspection of Steel Components (PISC) are described and results of each phase are presented. Eventually, problems related to the examination of austenitic welds are described. Special techniques for the ultrasonic examination of these welds are then presented. (TEC)

  14. The state-of-the-art of the established conventional and advanced NDE-techniques and procedures for defect detection and sizing

    Energy Technology Data Exchange (ETDEWEB)

    Crutzen, S; Edelmann, X

    1988-12-31

    This document presents several non-destructive ultrasonic techniques used for the inspection of various welds. Some probes are described and acoustic holography is presented as well as the time-of-flight diffraction (TOFD) technique. The three phases of the Programme for the Inspection of Steel Components (PISC) are described and results of each phase are presented. Eventually, problems related to the examination of austenitic welds are described. Special techniques for the ultrasonic examination of these welds are then presented. (TEC). 24 refs.

  15. Establishing a Modern Ground Network for Space Geodesy Applications

    Science.gov (United States)

    Pearlman, M.; Pavlis, E.; Altamimi, Z.; Noll, C.

    2010-01-01

    Ground-based networks of co-located space-geodesy techniques (VLBI, SLR, GLASS, DORIS) are the basis for the development and maintenance of the :International Terrestrial deference Frame (ITRE), which is the basis for our metric measurements of global change. The Global Geodetic Observing System (GGOS) within the International Association of Geodesy has established a task to develop a strategy to design, integrate and maintain the fundamental geodetic network and supporting infrastructure in a sustainable way to satisfy the long-term requirements for the reference frame. The GGOS goal is an origin definition at I mm or better and a temporal stability on the order of 0.1 mm/y, with similar numbers for the scale and orientation components. These goals are based on scientific requirements to address sea level rise with confidence. As a first step, simulations focused on establishing the optimal global SLR and VLBI network, since these two techniques alone are sufficient to define the reference frame. The GLASS constellations will then distribute the reference frame to users anywhere on the Earth. Using simulated data to be collected by the future networks, we investigated various designs and the resulting accuracy in the origin, scale and orientation of the resulting ITRF. We present here the results of extensive simulation studies aimed at designing optimal global geodetic networks to support GGOS science products. Current estimates are the network will require 24 - 32 globally distributed co-location sites. Stations in the near global network will require geologically stable sites witla good weather, established infrastructure, and local support and personnel. EGOS will seek groups that are interested in participation. GGOS intends to issues a Call for Participation of groups that would like to take part in the network implementation and operation_ Some examples of integrated stations currently in operation or under development will be presented. We will examine

  16. Establishment of a Methanogenic Benzene-Degrading Culture and its Implication in Bioremediation

    Science.gov (United States)

    Qiao, W.; Luo, F.; Bawa, N.; Guo, S.; Ye, S.; Edwards, E.

    2017-12-01

    Benzene is a known human carcinogen and it is a common pollutant in groundwater, mainly resulting from petrochemical industry. Anaerobic degradation of benzene has significant advantages over aerobic processes for in situ bioremediation. In this study, new methanogenic and sulfate-reducing benzene degrading cultures have been enriched. Microbial community composition was characterized with two other previously established benzene-degrading cultures, and their potential use in bioaugmentation is investigated. In this study, a lab microcosm study was conducted anaerobically with contaminated soil and groundwater from a former chemical plant. Benzene degradation was observed in the presence of co-contaminants and electron donor. Through repetitive amendment of benzene, two enrichment cultures have been developed under sulfate and methanogenic conditions. Results from DNA amplicon sequencing and qPCR analysis revealed that an organism similar to previously described benzene-degrading Deltaproteobacterium has been enriched. The microbial community of this culture was compared with other two methanogenic benzene-degrading enrichment cultures that were derived from an oil refinery and a decommissioned gasoline station, and have been maintained for decades. Deltaproteobacterium ORM2-like microbes were dominate in all enrichment cultures, which brought to light benzene-degrading microbes, ORM2 were enriched under different geological conditions distributed around the world. The relative abundance of methanogens was much lower compared to previously established cultures, although substantial amount of methane was produced. The peripheral organisms also vary. To investigate effectiveness of using ORM2-dominant enrichment cultures in bioremediation, microcosm studies were set up using contaminated materials, and a ORM2-dominating methanogenic benzene-degrading culture was used for bioaugmentation. Results revealed that benzene degradation was speeded up under methanogenic or

  17. In vitro establishment of Eugenia squarrose: an endemic species in danger of extinction from Santa Clara (Cuba

    Directory of Open Access Journals (Sweden)

    Elisa Quiala

    2004-01-01

    Full Text Available The tissue culture techniques can be supplemented with others that are carried out in the cultivation in situ and being applied in combined way to give solution to the extinction of different species. Eugenia squarrosa (Ekman & Urban it is an endemic species of Cuba in extinction danger due to the urbanization of their natural habitat, which have been reduced to a few hectares. The aim of this work was to achieve the establishment in vitro of this species. Seeds and young branches were collected starting from plants in its natural habitat. The effect of three concentrations of NaOCl (2.0, 2.5, 3.0% during 20 minutes in the disinfection of the seeds was studied. For the disinfection of the buds a treatment with alcohol to 70% was used during two minutes previously to the disinfection with NaOCl. The effect of three concentrations of this NaOCl was studied (1.0, 2.0, 3.0% during 10 minutes. The present microbiota was characterized in the contaminated branch. The 100% of disinfection of the seeds was achieved in all the treatments studied. The bigger explants percentage free of contaminant (88.6% was obtained in the treatment with 3% of NaOCl. However the biggest percentage of survival (45.7% was obtained when 2.0% of NaOCl was used. The establishment in vitro of the species was achieved starting from seeds and buds collected of field plants. Key Words: biodiversity, micropropagation, threatened species

  18. Propagation of pistachio applying in vitro culture techniques

    OpenAIRE

    Marín Velázquez, Juan Antonio; García Martín, Elena; Lorente Alonso, Pilar; Arbeloa Matute, Arancha; Andreu Puyal, Pilar

    2017-01-01

    8 Pags.- 2 Tabls.- 2 Figs. Article derived of a previous contribution of the authors to VI International Symposium on Production and Establishment of Micropropagated Plants (San Remo, Italy. April 2015). The defnitive version is available at: https://www.actahort.org/index.htm

  19. SOCIAL ADAPTATION OF PERSONS WITH DISABILITIES THROUGH ESTABLISHMENT OF PUBLIC REHABILITATION CENTRES

    Directory of Open Access Journals (Sweden)

    Tesler Kirill Igorevich

    2012-10-01

    The solution is to establish public rehabilitation centres that perform recreational, educational, sports, cultural, social, technological and production functions. This solution is most needed for blind and visually impaired people, because they experience particular problems in travelling in the urban environment. Establishment of the barrier-free environment can solve the problem of socialization of disabled people, because it contemplates all functional processes that they need. Integration of various functional units within public rehabilitation centres helps improve the living conditions of disabled people, and at the same time it contributes to the profitability of these centres as a whole and provides the necessary impetus boosting the development of techniques and technologies required for low mobility groups of people.

  20. Vibration transducer calibration techniques

    Science.gov (United States)

    Brinkley, D. J.

    1980-09-01

    Techniques for the calibration of vibration transducers used in the Aeronautical Quality Assurance Directorate of the British Ministry of Defence are presented. Following a review of the types of measurements necessary in the calibration of vibration transducers, the performance requirements of vibration transducers, which can be used to measure acceleration, velocity or vibration amplitude, are discussed, with particular attention given to the piezoelectric accelerometer. Techniques for the accurate measurement of sinusoidal vibration amplitude in reference-grade transducers are then considered, including the use of a position sensitive photocell and the use of a Michelson laser interferometer. Means of comparing the output of working-grade accelerometers with that of previously calibrated reference-grade devices are then outlined, with attention given to a method employing a capacitance bridge technique and a method to be used at temperatures between -50 and 200 C. Automatic calibration procedures developed to speed up the calibration process are outlined, and future possible extensions of system software are indicated.

  1. Engineers find climbing techniques work well for dam inspections

    Energy Technology Data Exchange (ETDEWEB)

    O`Shea, M.; Graves, A. [Bureau of Reclamation, Denver, CO (United States)

    1996-10-01

    Climbing techniques adopted by the Bureau of Reclamation to inspect previously inaccessible or difficult to reach features at dams are described. Following the failure of the steel radial-arm gate at Folsom Dam, engineers mounted an effort to reach and inspect the dam`s seven other spillway gates. This close-up examination was performed to: (1) determine the condition of these gates; and (2) gather clues about the failure of the one gate. The access techniques described involved mountaineering techniques, as opposed to high scaling techniques, performed with dynamic and static nylon kermantle ropes.

  2. A case series of re-establishment of neuromuscular block with rocuronium after sugammadex reversal.

    Science.gov (United States)

    Iwasaki, Hajime; Sasakawa, Tomoki; Takahoko, Kenichi; Takagi, Shunichi; Nakatsuka, Hideki; Suzuki, Takahiro; Iwasaki, Hiroshi

    2016-06-01

    We report the use of rocuronium to re-establish neuromuscular block after reversal with sugammadex. The aim of this study was to investigate the relationship between the dose of rocuronium needed to re-establish neuromuscular block and the time interval between sugammadex administration and re-administration of rocuronium. Patients who required re-establishment of neuromuscular block within 12 h after the reversal of rocuronium-induced neuromuscular block with sugammadex were included. After inducing general anesthesia and placing the neuromuscular monitor, the protocol to re-establish neuromuscular block was as follows. An initial rocuronium dose of 0.6 mg/kg was followed by additional 0.3 mg/kg doses every 2 min until train-of-four responses were abolished. A total of 11 patients were enrolled in this study. Intervals between sugammadex and second rocuronium were 12-465 min. Total dose of rocuronium needed to re-establish neuromuscular block was 0.6-1.2 mg/kg. 0.6 mg/kg rocuronium re-established neuromuscular block in all patients who received initial sugammadex more than 3 h previously. However, when the interval between sugammadex and second rocuronium was less than 2 h, more than 0.6 mg/kg rocuronium was necessary to re-establish neuromuscular block.

  3. The Delphi technique in radiography education research

    International Nuclear Information System (INIS)

    John-Matthews, J.St.; Wallace, M.J.; Robinson, L.

    2017-01-01

    Objectives: To describe and review the Delphi technique as a tool for radiographers engaged in mixed-methods research whereby agreement is required on the proficiencies needed by educational programmes for pre- and post- registration radiographers. This is achieved through a description offering a brief history of the technique. Through a literature search, radiography education research using this technique is identified. A protocol for a research project using the technique is presented. Using this worked example, advantages and disadvantages of the method are explored including sampling of participants, sample size, number of rounds and methods of feedback. Key findings: There are limited examples of the use of the Delphi technique in radiography literature including considerations on how to select experts and panel size. Conclusion: The Delphi technique is a suitable method for establishing collective agreement in the design of radiography educational interventions. Additional research is needed to deepen this evidence-based knowledge. - Highlights: • The Delphi Technique is used to gain collective agreement in forecasting healthcare education priorities. • There is increase of the use of the technique in healthcare education literature. • There are some examples of the technique in radiography education research. • A worked example of this technique is provided to critically evaluate this tool.

  4. Parachute technique for partial penectomy

    Directory of Open Access Journals (Sweden)

    Fernando Korkes

    2010-04-01

    Full Text Available PURPOSE: Penile carcinoma is a rare but mutilating malignancy. In this context, partial penectomy is the most commonly applied approach for best oncological results. We herein propose a simple modification of the classic technique of partial penectomy, for better cosmetic and functional results. TECHNIQUE: If partial penectomy is indicated, the present technique can bring additional benefits. Different from classical technique, the urethra is spatulated only ventrally. An inverted "V" skin flap with 0.5 cm of extension is sectioned ventrally. The suture is performed with vicryl 4-0 in a "parachute" fashion, beginning from the ventral portion of the urethra and the "V" flap, followed by the "V" flap angles and than by the dorsal portion of the penis. After completion of the suture, a Foley catheter and light dressing are placed for 24 hours. CONCLUSIONS: Several complex reconstructive techniques have been previously proposed, but normally require specific surgical abilities, adequate patient selection and staged procedures. We believe that these reconstructive techniques are very useful in some specific subsets of patients. However, the technique herein proposed is a simple alternative that can be applied to all men after a partial penectomy, and takes the same amount of time as that in the classic technique. In conclusion, the "parachute" technique for penile reconstruction after partial amputation not only improves the appearance of the penis, but also maintains an adequate function.

  5. Review of Nipple Reconstruction Techniques and Introduction of V to Y Technique in a Bilateral Wise Pattern Mastectomy or Reduction Mammaplasty

    OpenAIRE

    Riccio, Charles A.; Zeiderman, Matthew R.; Chowdhry, Saeed; Wilhelmi, Bradon J.

    2015-01-01

    Introduction: Nipple-areola complex reconstruction (NAR) is the final procedure in breast reconstruction after the majority of mastectomies. Many methods of NAR have been described, each with inherent advantages and disadvantages depending on local healthy tissue availability, previous scarring and procedures, and the operative morbidity of the NAR technique. Nipple reconstructions may be complicated by scars or previous nipple reconstruction, making the procedure more challenging. We propose...

  6. Errorless discrimination established by differential autoshaping.

    Science.gov (United States)

    Wilkie, D M; Ramer, D G

    1974-09-01

    In Experiment I, pigeons exposed to a differential autoshaping procedure pecked a key in the presence of the stimulus associated with reinforcement but did not peck, or pecked infrequently, in the presence of the stimulus associated with nonreinforcement. In Experiment II, pigeons were exposed to a differential autoshaping procedure in which one stimulus was associated with reinforcement and two stimuli were associated with nonreinforcement. The birds initially responded in the presence of one stimulus associated with nonreinforcement but never responded in the presence of the second stimulus associated with nonreinforcement. They were subsequently exposed to an autoshaping procedure in which reinforcement followed both these stimuli. The number of stimulus-reinforcement pairings required to establish pecking in the presence of the stimulus during which responses had not previously occurred suggested that such stimuli are inhibitory. These findings have implications for autoshaping, errorless discrimination, inhibition, and theories of discrimination byproducts.

  7. Olfactory memory established during trophallaxis affects food search behaviour in ants

    OpenAIRE

    Provecho, Y.; Josens, R.

    2009-01-01

    Camponotus mus ants can associate sucrose and odour at the source during successive foraging cycles and use this memory to locate the nectar in the absence of other cues. These ants perform conspicuous trophallactic behaviour during recruitment while foraging for nectar. In this work, we studied whether Camponotus mus ants are able to establish this odour-sucrose association in the social context of trophallaxis and we evaluated this memory in another context previously experienced by the ant...

  8. Establishing native warm season grasses on Eastern Kentucky strip mines

    Energy Technology Data Exchange (ETDEWEB)

    Barnes, T.G.; Larkin, J.L.; Arnett, M.B. [Univ. of Kentucky, Lexington, KY (United States). Dept. of Forestry

    1998-12-31

    The authors evaluated various methods of establishing native warm season grasses on two reclaimed Eastern Kentucky mines from 1994--1997. Most current reclamation practices incorporate the use of tall fescue (Festuca arundinacea) and other cool-season grasses/legumes that provide little wildlife habitats. The use of native warm season grasses will likely improve wildlife habitat on reclaimed strip mines. Objectives of this study were to compare the feasibility of establishing these grasses during fall, winter, or spring using a native rangeland seeder or hydroseeding; a fertilizer application at planting; or cold-moist stratification prior to hydroseeding. Vegetative cover, bare ground, species richness, and biomass samples were collected at the end of each growing season. Native warm season grass plantings had higher plant species richness compared to cool-season reclamation mixtures. There was no difference in establishment of native warm season grasses as a result of fertilization or seeding technique. Winter native warm season grass plantings were failures and cold-moist stratification did not increase plant establishment during any season. As a result of a drought during 1997, both cool-season and warm season plantings were failures. Cool-season reclamation mixtures had significantly more vegetative cover and biomass compared to native warm season grass mixtures and the native warm season grass plantings did not meet vegetative cover requirements for bond release. Forbs and legumes that established well included pale purple coneflower (Echinacea pallida), lance-leaf coreopsis (Coreopsis lanceolata), round-headed lespedeza (Lespedeza capitata), partridge pea (Cassia fasiculata), black-eyed susan (Rudbeckia hirta), butterfly milkweed (Asclepias tuberosa), and bergamot (Monarda fistulosa). Results from two demonstration plots next to research plots indicate it is possible to establish native warm season grasses on Eastern Kentucky strip mines for wildlife habitat.

  9. Establishing native warm season grasses on Eastern Kentucky strip mines

    International Nuclear Information System (INIS)

    Barnes, T.G.; Larkin, J.L.; Arnett, M.B.

    1998-01-01

    The authors evaluated various methods of establishing native warm season grasses on two reclaimed Eastern Kentucky mines from 1994--1997. Most current reclamation practices incorporate the use of tall fescue (Festuca arundinacea) and other cool-season grasses/legumes that provide little wildlife habitats. The use of native warm season grasses will likely improve wildlife habitat on reclaimed strip mines. Objectives of this study were to compare the feasibility of establishing these grasses during fall, winter, or spring using a native rangeland seeder or hydroseeding; a fertilizer application at planting; or cold-moist stratification prior to hydroseeding. Vegetative cover, bare ground, species richness, and biomass samples were collected at the end of each growing season. Native warm season grass plantings had higher plant species richness compared to cool-season reclamation mixtures. There was no difference in establishment of native warm season grasses as a result of fertilization or seeding technique. Winter native warm season grass plantings were failures and cold-moist stratification did not increase plant establishment during any season. As a result of a drought during 1997, both cool-season and warm season plantings were failures. Cool-season reclamation mixtures had significantly more vegetative cover and biomass compared to native warm season grass mixtures and the native warm season grass plantings did not meet vegetative cover requirements for bond release. Forbs and legumes that established well included pale purple coneflower (Echinacea pallida), lance-leaf coreopsis (Coreopsis lanceolata), round-headed lespedeza (Lespedeza capitata), partridge pea (Cassia fasiculata), black-eyed susan (Rudbeckia hirta), butterfly milkweed (Asclepias tuberosa), and bergamot (Monarda fistulosa). Results from two demonstration plots next to research plots indicate it is possible to establish native warm season grasses on Eastern Kentucky strip mines for wildlife habitat

  10. 49 CFR 173.23 - Previously authorized packaging.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Previously authorized packaging. 173.23 Section... REQUIREMENTS FOR SHIPMENTS AND PACKAGINGS Preparation of Hazardous Materials for Transportation § 173.23 Previously authorized packaging. (a) When the regulations specify a packaging with a specification marking...

  11. Imaging techniques for myocardial inflammation

    International Nuclear Information System (INIS)

    O'Connell, J.B.; Henkin, R.E.; Robinson, J.A.

    1986-01-01

    Dilated cardiomyopathy (DC) represents a heterogeneous group of disorders which results in morbidity and mortality in young individuals. Recent evidence suggests that a subset of these patients have histologic evidence of myocarditis which is potentially treatable with immunosuppression. The identification of myocardial inflammation may therefore lead to development of therapeutic regimens designed to treat the cause rather than the effect of the myocardial disease. Ultimately, this may result in improvement in the abysmal prognosis of DC. The currently accepted technique for identification of active myocardial inflammation is endomyocardial biopsy. This technique is not perfect, however, since pathologic standards for the diagnosis of myocarditis have not been established. Furthermore, focal inflammation may give rise to sampling error. The inflammation-avid radioisotope gallium-67 citrate has been used as an adjunct to biopsy improving the yield of myocarditis from 7 percent to 36 percent. Serial imaging correlates well to biopsy results. Future studies are designed to study the applicability of lymphocyte labelling techniques to myocardial inflammatory disease

  12. Decree 435/994 Environmental Impacts : establish a standard joint complex named Evaluation Regulations

    International Nuclear Information System (INIS)

    1994-01-01

    The Regulation of Evaluation of environmental Impact in the chapter I art.2 item 14 it establishes that It will require the previous Environmental Authorization the activities that refer to the construction of production factories and transformation of Nuclear Energy r, without damage of that settled down for the articulate 215 of the law 16.226 of October 29 1991 [es

  13. LANDING TECHNIQUES IN BEACH VOLLEYBALL

    Directory of Open Access Journals (Sweden)

    Markus Tilp

    2013-09-01

    Full Text Available The aims of the present study were to establish a detailed and representative record of landing techniques (two-, left-, and right-footed landings in professional beach volleyball and compare the data with those of indoor volleyball. Beach volleyball data was retrieved from videos taken at FIVB World Tour tournaments. Landing techniques were compared in the different beach and indoor volleyball skills serve, set, attack, and block with regard to sex, playing technique, and court position. Significant differences were observed between men and women in landings following block actions (χ²(2 = 18.19, p < 0.01 but not following serve, set, and attack actions. Following blocking, men landed more often on one foot than women. Further differences in landings following serve and attack with regard to playing technique and position were mainly observed in men. The comparison with landing techniques in indoor volleyball revealed overall differences both in men (χ²(2 = 161.4, p < 0.01 and women (χ²(2 = 84.91, p < 0.01. Beach volleyball players land more often on both feet than indoor volleyball players. Besides the softer surface in beach volleyball, and therefore resulting lower loads, these results might be another reason for fewer injuries and overuse conditions compared to indoor volleyball

  14. Landing Techniques in Beach Volleyball

    Science.gov (United States)

    Tilp, Markus; Rindler, Michael

    2013-01-01

    The aims of the present study were to establish a detailed and representative record of landing techniques (two-, left-, and right-footed landings) in professional beach volleyball and compare the data with those of indoor volleyball. Beach volleyball data was retrieved from videos taken at FIVB World Tour tournaments. Landing techniques were compared in the different beach and indoor volleyball skills serve, set, attack, and block with regard to sex, playing technique, and court position. Significant differences were observed between men and women in landings following block actions (χ2(2) = 18.19, p volleyball revealed overall differences both in men (χ2(2) = 161.4, p volleyball players land more often on both feet than indoor volleyball players. Besides the softer surface in beach volleyball, and therefore resulting lower loads, these results might be another reason for fewer injuries and overuse conditions compared to indoor volleyball. Key Points About 1/3 of all jumping actions in beach volleyball result in a landing on one foot. Especially following block situations men land on one foot more often than women. Landing techniques are related to different techniques and positions. Landings on one foot are less common in beach volleyball than indoor volleyball. This could be a reason for fewer injuries and overuse conditions. PMID:24149150

  15. 22 CFR 40.91 - Certain aliens previously removed.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Certain aliens previously removed. 40.91... IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Aliens Previously Removed § 40.91 Certain aliens previously removed. (a) 5-year bar. An alien who has been found inadmissible, whether as a result...

  16. Karolinska prostatectomy: a robot-assisted laparoscopic radical prostatectomy technique.

    Science.gov (United States)

    Nilsson, Andreas E; Carlsson, Stefan; Laven, Brett A; Wiklund, N Peter

    2006-01-01

    The last decade has witnessed an increasing trend towards minimally invasive management of prostate cancer, including laparoscopic and, more recently, robot-assisted laparoscopic prostatectomy. Several different laparoscopic approaches have been continuously developed during the last 5 years and it is still unclear which technique yields the best outcome. We present our current technique of robot-assisted laparoscopic radical prostatectomy. The technique described has evolved during the course of >400 robotic prostatectomies performed by the robotic team since the robot-assisted laparoscopic radical prostatectomy program was introduced at Karolinska University Hospital in January 2002. Our procedure comprises several modifications of previously reported ones, and we utilize fewer robotic instruments to reduce costs. An extended posterior dissection is performed to aid in the bladder neck-sparing dissection. In nerve-sparing procedures the vesicles are divided to avoid damage to the erectile nerves. In order to preserve the apical anatomy the dorsal venous complex is incised sharply and is first over-sewn after the apical dissection is completed. Our technique enables a more fluent dissection than previously described robotic techniques. Minimizing changes of instruments and the camera not only cuts costs but also reduces inefficient operating maneuvers, such as switching between 30 degrees and 0 degrees lenses during the procedure. We present a technique which in our hands has achieved excellent functional and oncological results.

  17. Engine control techniques to account for fuel effects

    Science.gov (United States)

    Kumar, Shankar; Frazier, Timothy R.; Stanton, Donald W.; Xu, Yi; Bunting, Bruce G.; Wolf, Leslie R.

    2014-08-26

    A technique for engine control to account for fuel effects including providing an internal combustion engine and a controller to regulate operation thereof, the engine being operable to combust a fuel to produce an exhaust gas; establishing a plurality of fuel property inputs; establishing a plurality of engine performance inputs; generating engine control information as a function of the fuel property inputs and the engine performance inputs; and accessing the engine control information with the controller to regulate at least one engine operating parameter.

  18. Do attitudes of families concerned influence features of children who claim to remember previous lives?

    Science.gov (United States)

    Pasricha, Satwant K

    2011-01-01

    Reported cases of nearly 2600 children (subjects) who claim to remember previous lives have been investigated in cultures with and without belief in reincarnation. The authenticity in most cases has been established. To study the influence of attitudes of parents of the subjects, families of the deceased person with whom they are identified and attention paid by others on the features of the cases. The study is based on field investigations. Data is derived from analysis of a larger series of an ongoing project. Information on initial and subsequent attitudes of subjects' mothers was available for 292 and 136 cases, respectively; attitudes of 227 families of deceased person (previous personality) with whom he is identified, and the extent of attention received from outsiders for 252 cases. Observations and interviews with multiple firsthand informants on both sides of the case as well as some neutral informants supplemented by examination of objective data were the chief methods of investigation. The initial attitude of mothers varied from encouragement (21%) to neutral or tolerance (51%) to discouragement (28%). However, it changed significantly from neutrality to taking measures to induce amnesia in their children for previous life memories due to various psychosocial pressures and prevalent beliefs. Families of the previous personalities, once convinced, showed complete acceptance in a majority of cases. Outside attention was received in 58% cases. The positive attitude of parents might facilitate expression of memories but subsequently attitudes of persons concerned do not seem to alter features of the cases.

  19. A Secure Trust Establishment Scheme for Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Farruh Ishmanov

    2014-01-01

    Full Text Available Trust establishment is an important tool to improve cooperation and enhance security in wireless sensor networks. The core of trust establishment is trust estimation. If a trust estimation method is not robust against attack and misbehavior, the trust values produced will be meaningless, and system performance will be degraded. We present a novel trust estimation method that is robust against on-off attacks and persistent malicious behavior. Moreover, in order to aggregate recommendations securely, we propose using a modified one-step M-estimator scheme. The novelty of the proposed scheme arises from combining past misbehavior with current status in a comprehensive way. Specifically, we introduce an aggregated misbehavior component in trust estimation, which assists in detecting an on-off attack and persistent malicious behavior. In order to determine the current status of the node, we employ previous trust values and current measured misbehavior components. These components are combined to obtain a robust trust value. Theoretical analyses and evaluation results show that our scheme performs better than other trust schemes in terms of detecting an on-off attack and persistent misbehavior.

  20. Video: two novel endoscopic esophageal lengthening and reconstruction techniques.

    Science.gov (United States)

    Perretta, Silvana; Wall, James K; Dallemagne, Bernard; Harrison, Michael; Becmeur, François; Marescaux, Jacques

    2011-10-01

    Esophageal reconstruction presents a significant clinical challenge in patients ranging from neonates with long-gap esophageal atresia to adults after esophageal resection. Both gastric and colonic replacement conduits carry significant morbidity. As emerging organ-sparring techniques become established for early stage esophageal tumors, less morbid reconstruction techniques are warranted. We present two novel endoscopic approaches for esophageal lengthening and reconstruction in a porcine model. Two models of esophageal defects were created in pigs (30-35 kg) under general anesthesia and subsequently reconstructed with the novel techniques. The first model was a segmental defect of the esophagus created by thoracoscopically transecting the esophagus above the gastroesophageal (GE) junction. The first reconstruction technique involved bilateral submucosal endoscopic lengthening myotomies (BSELM) with a magnetic compression anastomosis (MAGNAMOSIS™). The second model was a wedge defect in the anterior esophagus created above the GE junction through a laparotomy. The second reconstruction technique involved an inverted mucosal-submucosal sleeve transposition graft (IMSTG) that crossed the esophageal gap and was secured in place with a self-expandable covered esophageal stent. Both techniques were feasible in the pig model. The BSELM approach lengthened the esophagus 1 cm for every 2 cm length of myotomy. The myotomy targeted only the inner circular fibers of the esophagus, with preservation of the longitudinal layer to protect against long-term dilation and pouching. The IMSTG approach generated a vascularized mucosal graft almost as long as the esophagus itself. Emerging endoscopic capabilities are enabling complex endoluminal esophageal procedures. BSELM and IMSTG are two novel and technically feasible approaches to esophageal lengthening and reconstruction. Further survival studies are needed to establish the safety and efficacy of these techniques.

  1. Establishing Natural Nootropics: Recent Molecular Enhancement Influenced by Natural Nootropic

    Directory of Open Access Journals (Sweden)

    Noor Azuin Suliman

    2016-01-01

    Full Text Available Nootropics or smart drugs are well-known compounds or supplements that enhance the cognitive performance. They work by increasing the mental function such as memory, creativity, motivation, and attention. Recent researches were focused on establishing a new potential nootropic derived from synthetic and natural products. The influence of nootropic in the brain has been studied widely. The nootropic affects the brain performances through number of mechanisms or pathways, for example, dopaminergic pathway. Previous researches have reported the influence of nootropics on treating memory disorders, such as Alzheimer’s, Parkinson’s, and Huntington’s diseases. Those disorders are observed to impair the same pathways of the nootropics. Thus, recent established nootropics are designed sensitively and effectively towards the pathways. Natural nootropics such as Ginkgo biloba have been widely studied to support the beneficial effects of the compounds. Present review is concentrated on the main pathways, namely, dopaminergic and cholinergic system, and the involvement of amyloid precursor protein and secondary messenger in improving the cognitive performance.

  2. Establishing Natural Nootropics: Recent Molecular Enhancement Influenced by Natural Nootropic.

    Science.gov (United States)

    Suliman, Noor Azuin; Mat Taib, Che Norma; Mohd Moklas, Mohamad Aris; Adenan, Mohd Ilham; Hidayat Baharuldin, Mohamad Taufik; Basir, Rusliza

    2016-01-01

    Nootropics or smart drugs are well-known compounds or supplements that enhance the cognitive performance. They work by increasing the mental function such as memory, creativity, motivation, and attention. Recent researches were focused on establishing a new potential nootropic derived from synthetic and natural products. The influence of nootropic in the brain has been studied widely. The nootropic affects the brain performances through number of mechanisms or pathways, for example, dopaminergic pathway. Previous researches have reported the influence of nootropics on treating memory disorders, such as Alzheimer's, Parkinson's, and Huntington's diseases. Those disorders are observed to impair the same pathways of the nootropics. Thus, recent established nootropics are designed sensitively and effectively towards the pathways. Natural nootropics such as Ginkgo biloba have been widely studied to support the beneficial effects of the compounds. Present review is concentrated on the main pathways, namely, dopaminergic and cholinergic system, and the involvement of amyloid precursor protein and secondary messenger in improving the cognitive performance.

  3. Approaches to characterization of nuclear material for establishment of nuclear forensics

    International Nuclear Information System (INIS)

    Okazaki, Hiro; Sumi, Mika; Sato, Mitsuhiro; Kayano, Masashi; Kageyama, Tomio; Shinohara, Nobuo; Martinez, Patrick; Xu, Ning; Thomas, Mariam; Porterfield, Donivan; Colletti, Lisa; Schwartz, Dan; Tandon, Lav

    2014-01-01

    The Plutonium Fuel Development Center (PFDC) of Japan Atomic Energy Agency has been analyzing isotopic compositions and contents of plutonium and uranium as well as trace impurities and physics in the nuclear fuel from MOX fuel fabrication process for accountancy and process control purpose. These analytical techniques are also effective for nuclear forensics to identify such as source, history, and route of the material by determining a composition and characterization of nuclear material. Therefore, PFDC cooperates with Los Alamos National Laboratory which has broad experience and established measurement skill for nuclear forensics, and evaluates the each method, procedure and analytical data toward R and D of characterizing a nuclear material for forensic purposes. This paper describes the approaches to develop characterization techniques of nuclear material for nuclear forensics purposes at PFDC. (author)

  4. Study of water flowrate using time transient and cross-correlation techniques with 82Br radiotracer

    International Nuclear Information System (INIS)

    Salgado, William L.; Brandao, Luiz E.B.

    2013-01-01

    This paper aims to determinate the water flowrate using Time Transient and Cross-Correlation techniques. The detection system uses two NaI (T1) detectors adequately positioned on the outside of pipe and a gamma-ray source ( 82 Br radiotracer). The water flowrate measurements using Time Transient and Cross-Correlation techniques were compared to invasive conventional measurements of the flowrate previously installed in pipeline. Discrepancies between Time Transient and Cross-Correlation techniques flowmeter previously installed in pipeline. Discrepancies between Time Transient and Cross-Correlation techniques flowrate values were found to be less than 3% in relation to conventional ones. (author)

  5. The Implementation of hydrogen mitigation techniques: summary and conclusions: OECD Workshop

    International Nuclear Information System (INIS)

    1996-01-01

    The OECD Workshop on the Implementation of Hydrogen Mitigation Techniques was held in Winnipeg, Canada from 1996 May 13 to 15. Sixty-five experts from twelve OECD Member countries and the Russian Federation attended the meeting. Thirty-five papers were presented in six sessions: accident management and analyses, relevant aspects of hydrogen production, distribution and mixing, engineering, technology, possible side-effects and consequences, new designs. The objectives of the Workshop were to establish the state-of-the-art of hydrogen mitigation techniques, with emphasis on igniters and catalytic recombiners, to exchange information on Member countries' strategies in managing hydrogen mitigation and to establish dialogue as to differences in approach, to determine whether there is now an adequate technical basis for such strategies or whether more work - in which areas - is desirable, and to exchange information on future plans for implementation of hydrogen mitigation techniques

  6. Multiple inflammatory biomarker detection in a prospective cohort study: a cross-validation between well-established single-biomarker techniques and an electrochemiluminescense-based multi-array platform.

    Directory of Open Access Journals (Sweden)

    Bas C T van Bussel

    Full Text Available BACKGROUND: In terms of time, effort and quality, multiplex technology is an attractive alternative for well-established single-biomarker measurements in clinical studies. However, limited data comparing these methods are available. METHODS: We measured, in a large ongoing cohort study (n = 574, by means of both a 4-plex multi-array biomarker assay developed by MesoScaleDiscovery (MSD and single-biomarker techniques (ELISA or immunoturbidimetric assay, the following biomarkers of low-grade inflammation: C-reactive protein (CRP, serum amyloid A (SAA, soluble intercellular adhesion molecule 1 (sICAM-1 and soluble vascular cell adhesion molecule 1 (sVCAM-1. These measures were realigned by weighted Deming regression and compared across a wide spectrum of subjects' cardiovascular risk factors by ANOVA. RESULTS: Despite that both methods ranked individuals' levels of biomarkers very similarly (Pearson's r all≥0.755 absolute concentrations of all biomarkers differed significantly between methods. Equations retrieved by the Deming regression enabled proper realignment of the data to overcome these differences, such that intra-class correlation coefficients were then 0.996 (CRP, 0.711 (SAA, 0.895 (sICAM-1 and 0.858 (sVCAM-1. Additionally, individual biomarkers differed across categories of glucose metabolism, weight, metabolic syndrome and smoking status to a similar extent by either method. CONCLUSIONS: Multiple low-grade inflammatory biomarker data obtained by the 4-plex multi-array platform of MSD or by well-established single-biomarker methods are comparable after proper realignment of differences in absolute concentrations, and are equally associated with cardiovascular risk factors, regardless of such differences. Given its greater efficiency, the MSD platform is a potential tool for the quantification of multiple biomarkers of low-grade inflammation in large ongoing and future clinical studies.

  7. Testosterone deficiency in dialysis patients: Differences according to the dialysis techniques

    Directory of Open Access Journals (Sweden)

    Secundino Cigarrán

    2017-09-01

    Conclusions: Circulating testosterone levels in men on dialysis were independently associated with HD technique. It can be concluded that a new factor—namely the dialysis technique—may be associated with falling testosterone levels and the associated loss of muscle mass and inflammation. Further studies are needed to establish whether the dialysis technique itself triggers testosterone elimination.

  8. Survey to explore understanding of the principles of aseptic technique: Qualitative content analysis with descriptive analysis of confidence and training.

    Science.gov (United States)

    Gould, Dinah J; Chudleigh, Jane; Purssell, Edward; Hawker, Clare; Gaze, Sarah; James, Deborah; Lynch, Mary; Pope, Nicola; Drey, Nicholas

    2018-04-01

    In many countries, aseptic procedures are undertaken by nurses in the general ward setting, but variation in practice has been reported, and evidence indicates that the principles underpinning aseptic technique are not well understood. A survey was conducted, employing a brief, purpose-designed, self-reported questionnaire. The response rate was 72%. Of those responding, 65% of nurses described aseptic technique in terms of the procedure used to undertake it, and 46% understood the principles of asepsis. The related concepts of cleanliness and sterilization were frequently confused with one another. Additionally, 72% reported that they not had received training for at least 5 years; 92% were confident of their ability to apply aseptic technique; and 90% reported that they had not been reassessed since their initial training. Qualitative analysis confirmed a lack of clarity about the meaning of aseptic technique. Nurses' understanding of aseptic technique and the concepts of sterility and cleanliness is inadequate, a finding in line with results of previous studies. This knowledge gap potentially places patients at risk. Nurses' understanding of the principles of asepsis could be improved. Further studies should establish the generalizability of the study findings. Possible improvements include renewed emphasis during initial nurse education, greater opportunity for updating knowledge and skills post-qualification, and audit of practice. Copyright © 2018 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

  9. Model technique for aerodynamic study of boiler furnace

    Energy Technology Data Exchange (ETDEWEB)

    1966-02-01

    The help of the Division was recently sought to improve the heat transfer and reduce the exit gas temperature in a pulverized-fuel-fired boiler at an Australian power station. One approach adopted was to construct from Perspex a 1:20 scale cold-air model of the boiler furnace and to use a flow-visualization technique to study the aerodynamic patterns established when air was introduced through the p.f. burners of the model. The work established good correlations between the behaviour of the model and of the boiler furnace.

  10. A reflexive exploration of two qualitative data coding techniques

    Directory of Open Access Journals (Sweden)

    Erik Blair

    2016-01-01

    Full Text Available In an attempt to help find meaning within qualitative data, researchers commonly start by coding their data. There are a number of coding systems available to researchers and this reflexive account explores my reflections on the use of two such techniques. As part of a larger investigation, two pilot studies were undertaken as a means to examine the relative merits of open coding and template coding for examining transcripts. This article does not describe the research project per se but attempts to step back and offer a reflexive account of the development of data coding tools. Here I reflect upon and evaluate the two data coding techniques that were piloted, and discuss how using appropriate aspects of both led to the development of my final data coding approach. My exploration found there was no clear-cut ‘best’ option but that the data coding techniques needed to be reflexively-aligned to meet the specific needs of my project. This reflection suggests that, when coding qualitative data, researchers should be methodologically thoughtful when they attempt to apply any data coding technique; that they do not assume pre-established tools are aligned to their particular paradigm; and that they consider combining and refining established techniques as a means to define their own specific codes. DOI: 10.2458/azu_jmmss.v6i1.18772DOI: 10.2458/azu_jmmss.v6i1.18772

  11. A Data Analysis Expert System For Large Established Distributed Databases

    Science.gov (United States)

    Gnacek, Anne-Marie; An, Y. Kim; Ryan, J. Patrick

    1987-05-01

    The purpose of this work is to analyze the applicability of artificial intelligence techniques for developing a user-friendly, parallel interface to large isolated, incompatible NASA databases for the purpose of assisting the management decision process. To carry out this work, a survey was conducted to establish the data access requirements of several key NASA user groups. In addition, current NASA database access methods were evaluated. The results of this work are presented in the form of a design for a natural language database interface system, called the Deductively Augmented NASA Management Decision Support System (DANMDS). This design is feasible principally because of recently announced commercial hardware and software product developments which allow cross-vendor compatibility. The goal of the DANMDS system is commensurate with the central dilemma confronting most large companies and institutions in America, the retrieval of information from large, established, incompatible database systems. The DANMDS system implementation would represent a significant first step toward this problem's resolution.

  12. Fundamentals of functional imaging I: current clinical techniques.

    Science.gov (United States)

    Luna, A; Martín Noguerol, T; Mata, L Alcalá

    2018-05-01

    Imaging techniques can establish a structural, physiological, and molecular phenotype for cancer, which helps enable accurate diagnosis and personalized treatment. In recent years, various imaging techniques that make it possible to study the functional characteristics of tumors quantitatively and reproducibly have been introduced and have become established in routine clinical practice. Perfusion studies enable us to estimate the microcirculation as well as tumor angiogenesis and permeability using ultrafast dynamic acquisitions with ultrasound, computed tomography, or magnetic resonance (MR) imaging. Diffusion-weighted sequences now form part of state-of-the-art MR imaging protocols to evaluate oncologic lesions in any anatomic location. Diffusion-weighted imaging provides information about the occupation of the extracellular and extravascular space and indirectly estimates the cellularity and apoptosis of tumors, having demonstrated its relation with biologic aggressiveness in various tumor lines and its usefulness in the evaluation of the early response to systemic and local targeted therapies. Another tool is hydrogen proton MR spectroscopy, which is used mainly in the study of the metabolic characteristics of brain tumors. However, the complexity of the technique and its lack of reproducibility have limited its clinical use in other anatomic areas, although much experience with the use of this technique in the assessment of prostate and breast cancers as well as liver lesions has also accumulated. This review analyzes the imaging techniques that make it possible to evaluate the physiological and molecular characteristics of cancer that have already been introduced into clinical practice, such as techniques that evaluate angiogenesis through dynamic acquisitions after the administration of contrast material, diffusion-weighted imaging, or hydrogen proton MR spectroscopy, as well as their principal applications in oncology. Copyright © 2018 SERAM. Publicado

  13. NASA/MSFC prediction techniques

    International Nuclear Information System (INIS)

    Smith, R.E.

    1987-01-01

    The NASA/MSFC method of forecasting is more formal than NOAA's. The data are smoothed by the Lagrangian method and linear regression prediction techniques are used. The solar activity period is fixed at 11 years--the mean period of all previous cycles. Interestingly, the present prediction for the time of the next solar minimum is February or March of 1987, which, within the uncertainties of two methods, can be taken to be the same as the NOAA result

  14. A role for glucocorticoids in the long-term establishment of a social hierarchy.

    Science.gov (United States)

    Timmer, Marjan; Sandi, Carmen

    2010-11-01

    Stress can affect the establishment and maintenance of social hierarchies. In the present study, we investigated the role of increasing corticosterone levels before or just after a first social encounter between two rats of a dyad in the establishment and the long-term maintenance of a social hierarchy. We show that pre-social encounter corticosterone treatment does not affect the outcome of the hierarchy during a first encounter, but induces a long-term memory for the hierarchy when the corticosterone-injected rat becomes dominant during the encounter, but not when it becomes subordinate. Post-social encounter corticosterone leads to a long-term maintenance of the hierarchy only when the subordinate rat of the dyad is injected with corticosterone. This corticosterone effect mimics previously reported actions of stress on the same model and, hence, implicates glucocorticoids in the consolidation of the memory for a recently established hierarchy. Copyright © 2010 Elsevier Ltd. All rights reserved.

  15. Repeated Surgical or Endoscopic Myotomy for Recurrent Dysphagia in Patients After Previous Myotomy for Achalasia.

    Science.gov (United States)

    Fumagalli, Uberto; Rosati, Riccardo; De Pascale, Stefano; Porta, Matteo; Carlani, Elisa; Pestalozza, Alessandra; Repici, Alessandro

    2016-03-01

    Surgical myotomy of the lower esophageal sphincter has a 5-year success rate of approximately 91 %. Peroral endoscopic myotomy can provide similar results for controlling dysphagia. Some patients experience either persistent or recurrent dysphagia after myotomy. We present here a retrospective analysis of our experience with redo myotomy for recurrent dysphagia in patients with achalasia. From March 1996 to February 2015, 234 myotomies for primary or recurrent achalasia were performed in our center. Fifteen patients (6.4 %) had had a previous myotomy and were undergoing surgical redo myotomy (n = 9) or endoscopic redo myotomy (n = 6) for recurrent symptoms. Patients presented at a median of 10.4 months after previous myotomy. Median preoperative Eckardt score was 6. Among the nine patients undergoing surgical myotomy, three esophageal perforations occurred intraoperatively (all repaired immediately). Surgery lasted 111 and 62 min on average (median) in the surgical and peroral endoscopic myotomy (POEM) groups, respectively. No postoperative complications occurred in either group. Median postoperative stay was 3 and 2.5 days in the surgical and POEM groups, respectively. In the surgical group, Eckardt score was dysphagia. Preliminary results using POEM indicate that the technique can be safely used in patients who have undergone previous surgical myotomy.

  16. A video authentication technique

    International Nuclear Information System (INIS)

    Johnson, C.S.

    1987-01-01

    Unattended video surveillance systems are particularly vulnerable to the substitution of false video images into the cable that connects the camera to the video recorder. New technology has made it practical to insert a solid state video memory into the video cable, freeze a video image from the camera, and hold this image as long as desired. Various techniques, such as line supervision and sync detection, have been used to detect video cable tampering. The video authentication technique described in this paper uses the actual video image from the camera as the basis for detecting any image substitution made during the transmission of the video image to the recorder. The technique, designed for unattended video systems, can be used for any video transmission system where a two-way digital data link can be established. The technique uses similar microprocessor circuitry at the video camera and at the video recorder to select sample points in the video image for comparison. The gray scale value of these points is compared at the recorder controller and if the values agree within limits, the image is authenticated. If a significantly different image was substituted, the comparison would fail at a number of points and the video image would not be authenticated. The video authentication system can run as a stand-alone system or at the request of another system

  17. Flow establishment behind blunt bodies at hypersonic speeds in a shock tunnel

    Science.gov (United States)

    Park, G.; Hruschka, R.; Gai, S. L.; Neely, A. J.

    2008-11-01

    An investigation of flow establishment behind two blunt bodies, a circular cylinder and a 45° half-angle blunted-cone was conducted. Unlike previous studies which relied solely on surface measurements, the present study combines these with unique high-speed visualisation to image the establishment of the flow structure in the base region. Test flows were generated using a free-piston shock tunnel at a nominal Mach number of 10. The freestream unit Reynolds numbers considered were 3.02x105/m and 1.17x106/m at total enthalpies of 13.35MJ/kg and 3.94MJ/kg, respectively. In general, the experiments showed that it takes longer to establish steady heat flux than pressure. The circular cylinder data showed that the near wake had a slight Reynolds number effect, where the size of the near wake was smaller for the high enthalpy flow condition. The blunted-cone data showed that the heat flux and pressures reached steady states in the near wake at similar times for both high and low enthalpy conditions.

  18. Laparoscopic feeding jejunostomy: also a simple technique.

    Science.gov (United States)

    Albrink, M H; Foster, J; Rosemurgy, A S; Carey, L C

    1992-01-01

    Placement of feeding tubes is a common procedure for general surgeons. While the advent of percutaneous endoscopic gastrostomy has changed and improved surgical practice, this technique is contraindicated in many circumstances. In some patients placement of feeding tubes in the stomach may be contraindicated due to the risks of aspiration, gastric paresis, or gastric dysmotility. We describe a technique of laparoscopic jejunostomy tube placement which is easy and effective. It is noteworthy that this method may be used in patients who have had previous abdominal operations, and it has the added advantage of a direct peritoneal view of the viscera. We suggest that qualified laparoscopic surgeons learn the technique of laparoscopic jejunostomy.

  19. Tendon 'turnover lengthening' technique.

    Science.gov (United States)

    Cerovac, S; Miranda, B H

    2013-11-01

    Tendon defect reconstruction is amongst the most technically challenging areas in hand surgery. Tendon substance deficiency reconstruction techniques include lengthening, grafting, two-stage reconstruction and tendon transfers, however each is associated with unique challenges over and above direct repair. We describe a novel 'turnover lengthening' technique for hand tendons that has successfully been applied to the repair of several cases, including a case of attritional flexor and traumatic extensor tendon rupture in two presented patients where primary tenorrhaphy was not possible. In both cases a good post-operative outcome was achieved, as the patients were happy having returned back to normal activities of daily living such that they were discharged 12 weeks post-operatively. Our technique avoids the additional morbidity and complications associated with grafting, transfers and two stage reconstructions. It is quick, simple and reproducible for defects not exceeding 3-4 cm, provides a means of immediate one stage reconstruction, no secondary donor site morbidity and does not compromise salvage by tendon transfer and/or two-stage reconstruction in cases of failure. To our knowledge no such technique has been previously been described to reconstruct such hand tendon defects. Crown Copyright © 2013. Published by Elsevier Ltd. All rights reserved.

  20. Acoustic techniques in nuclear safeguards

    International Nuclear Information System (INIS)

    Olinger, C.T.; Sinha, D.N.

    1995-01-01

    Acoustic techniques can be employed to address many questions relevant to current nuclear technology needs. These include establishing and monitoring intrinsic tags and seals, locating holdup in areas where conventional radiation-based measurements have limited capability, process monitoring, monitoring containers for corrosion or changes in pressure, and facility design verification. These acoustics applications are in their infancy with respect to safeguards and nuclear material management, but proof-of-principle has been demonstrated in many of the areas listed

  1. 3D temporal subtraction on multislice CT images using nonlinear warping technique

    Science.gov (United States)

    Ishida, Takayuki; Katsuragawa, Shigehiko; Kawashita, Ikuo; Kim, Hyounseop; Itai, Yoshinori; Awai, Kazuo; Li, Qiang; Doi, Kunio

    2007-03-01

    The detection of very subtle lesions and/or lesions overlapped with vessels on CT images is a time consuming and difficult task for radiologists. In this study, we have developed a 3D temporal subtraction method to enhance interval changes between previous and current multislice CT images based on a nonlinear image warping technique. Our method provides a subtraction CT image which is obtained by subtraction of a previous CT image from a current CT image. Reduction of misregistration artifacts is important in the temporal subtraction method. Therefore, our computerized method includes global and local image matching techniques for accurate registration of current and previous CT images. For global image matching, we selected the corresponding previous section image for each current section image by using 2D cross-correlation between a blurred low-resolution current CT image and a blurred previous CT image. For local image matching, we applied the 3D template matching technique with translation and rotation of volumes of interests (VOIs) which were selected in the current and the previous CT images. The local shift vector for each VOI pair was determined when the cross-correlation value became the maximum in the 3D template matching. The local shift vectors at all voxels were determined by interpolation of shift vectors of VOIs, and then the previous CT image was nonlinearly warped according to the shift vector for each voxel. Finally, the warped previous CT image was subtracted from the current CT image. The 3D temporal subtraction method was applied to 19 clinical cases. The normal background structures such as vessels, ribs, and heart were removed without large misregistration artifacts. Thus, interval changes due to lung diseases were clearly enhanced as white shadows on subtraction CT images.

  2. Enhanced protein electrophoresis technique for separating human skeletal muscle myosin heavy chain isoforms

    Science.gov (United States)

    Bamman, M. M.; Clarke, M. S.; Talmadge, R. J.; Feeback, D. L.

    1999-01-01

    Talmadge and Roy (J. Appl. Physiol. 1993, 75, 2337-2340) previously established a sodium dodecyl sulfate - polyacrylamide gel electrophoresis (SDS-PAGE) protocol for separating all four rat skeletal muscle myosin heavy chain (MHC) isoforms (MHC I, IIa, IIx, IIb); however, when applied to human muscle, the type II MHC isoforms (Ila, IIx) are not clearly distinguished. In this brief paper we describe a modification of the SDS-PAGE protocol which yields distinct and consistent separation of all three adult human MHC isoforms (MHC I, IIa, IIx) in a minigel system. MHC specificity of each band was confirmed by Western blot using three monoclonal IgG antibodies (mAbs) immunoreactive against MHCI (mAb MHCs, Novacastra Laboratories), MHCI+IIa (mAb BF-35), and MHCIIa+IIx (mAb SC-71). Results provide a valuable SDS-PAGE minigel technique for separating MHC isoforms in human muscle without the difficult task of casting gradient gels.

  3. Evaluation of Damping Using Time Domain OMA Techniques

    DEFF Research Database (Denmark)

    Bajric, Anela; Brincker, Rune; Georgakis, Christos T.

    2014-01-01

    . In this paper a comparison is made of the effectiveness of three existing OMA techniques in providing accurate damping estimates for varying loadings, levels of noise, number of added measurement channels and structural damping. The evaluated techniques are derived in the time domain and are namely the Ibrahim...... Time Domain (ITD), Eigenvalue Realization Algorithm (ERA) and the Polyreference Time Domain (PTD). The response of a two degree-of-freedom (2DOF) system is numerically established from specified modal parameters with well separated and closely spaced modes. Two types of response are considered, free...

  4. Establishing structure-property correlations and classification of base oils using statistical techniques and artificial neural networks

    International Nuclear Information System (INIS)

    Kapur, G.S.; Sastry, M.I.S.; Jaiswal, A.K.; Sarpal, A.S.

    2004-01-01

    The present paper describes various classification techniques like cluster analysis, principal component (PC)/factor analysis to classify different types of base stocks. The API classification of base oils (Group I-III) has been compared to a more detailed NMR derived chemical compositional and molecular structural parameters based classification in order to point out the similarities of the base oils in the same group and the differences between the oils placed in different groups. The detailed compositional parameters have been generated using 1 H and 13 C nuclear magnetic resonance (NMR) spectroscopic methods. Further, oxidation stability, measured in terms of rotating bomb oxidation test (RBOT) life, of non-conventional base stocks and their blends with conventional base stocks, has been quantitatively correlated with their 1 H NMR and elemental (sulphur and nitrogen) data with the help of multiple linear regression (MLR) and artificial neural networks (ANN) techniques. The MLR based model developed using NMR and elemental data showed a high correlation between the 'measured' and 'estimated' RBOT values for both training (R=0.859) and validation (R=0.880) data sets. The ANN based model, developed using fewer number of input variables (only 1 H NMR data) also showed high correlation between the 'measured' and 'estimated' RBOT values for training (R=0.881), validation (R=0.860) and test (R=0.955) data sets

  5. Dispersion microclimatology of the Whiteshell Nuclear Research Establishment: 1964-1976

    International Nuclear Information System (INIS)

    Davis, P.A.; Reimer, A.

    1980-10-01

    This report discusses the analysis of data collected on the meteorological tower at the Whiteshell Nuclear Research Establishment (WNRE) during the period 1964-1976. The time-averaged characteristics of wind speed, wind direction, temperature and atmospheric stability are described, and the implications which these chacteristics have for the dispersion of a contaminant released to the atmosphere from the WNRE site are discussed. A comparison of the present results with those of a previous two-year analysis of WNRE measurements suggests that a short-term climatology is sufficiently representative of long-term conditions to provide a reliable base for dispersion predictions. (auth)

  6. Recent progress on developments of tritium safe handling techniques in Japan

    International Nuclear Information System (INIS)

    Watanabe, Kuniaki; Matsuyama, Masao

    1993-01-01

    Vast amounts of tritium will be used for thermonuclear fusion reactors. Without establishing safe handling techniques for large amounts of tritium, undoubtedly the fusion reactors will not be accepted. Japanese activity on tritium related research has considerably developed in the last 10 years. This review paper gives a brief summary of safe handling techniques developed by Japanese research groups. (author)

  7. Dante's Comedy: precursors of psychoanalytic technique and psyche.

    Science.gov (United States)

    Szajnberg, Nathan Moses

    2010-02-01

    This paper uses a literary approach to explore what common ground exists in both psychoanalytic technique and views of the psyche, of 'person'. While Western literature has developed various views of psyche and person over centuries, there have been crystallizing, seminal portraits, for instance Shakespeare's perspective on what is human, some of which have endured to the present. By using Dante's Commedia, particularly the Inferno, a 14th century poem that both integrates and revises previous models of psyche and personhood, we can examine what features of psyche, and 'techniques' in soul-healing psychoanalysts have inherited culturally. Discovering basic features of technique and model of psyche we share as psychoanalysts permits us to explore why we have differences in variations on technique and models of inner life.

  8. Role of the IAEA in establishment of the international standards of radiation protection

    International Nuclear Information System (INIS)

    Pinak, M.

    2014-01-01

    The aim of the presentation is to highlight the existing challenges in radiation protection, and provide insight into the role of the IAEA in establishment of the radiation safety standards. It will, inter alia, cover from the following areas: 1. global outreach of safety principles in radiation protection and safety; 2. IAEA and establishment of Safety Standards; 3. IAEA Standards and national regulations; 4. IAEA members states role in drafting and review of IAEA Safety Standards; 5. existing, novel issues and challenges. The role of the IAEA is to establish fundamental safety objectives in radiation protection and safety following fundamental safety objectives, safety principles and concepts. The main aim of Safety Standards is to provide for the establishment of a system for protection of people and the environment from harmful effects of ionizing radiation. The requirements as included in the Safety Standards aim to assess, manage and control exposure to radiation so that radiation risks, including risks of health effects and risks to the environment, are reduced to the extent reasonably achievable.One of the novel feature adopted in the revised Basic Safety Standards (BSS) is the classification of exposures - planned, emergency and existing - each of them including several categories of exposure (occupational, public and medical), where appropriate.The revised BSS also addresses areas like exemption and clearance being particularly important in international trade and transport; significantly increases the number of requirements in medicine, in response to novel and/or expanding techniques in medicine using ionizing radiation; incorporates new regulatory limits for exposure to radon, and in protection of the lens of the eyes, as recommended by WHO and ICRP; newly introduces requirements for specific practices like, for example, airport security screenings; and addresses many other areas.While the principal approach to regulatory aspects in emergency exposure

  9. Development of analytical techniques for determining rare earth elements in geological materials

    International Nuclear Information System (INIS)

    Moraes, Noemia M.P. de; Kakazu, M.H.; Iyer, S.S.

    1987-01-01

    This work presents a comparative study between instrumental neutron activation analysis, inductively coupled plasma emission spectrometry and mass spectrometric isotope dilution techniques. Some advantages and disadvantages of the techniques are presented, depending on the type of the analysis required. Emphasis in give upon mass spectrometric isotope dilution, and some procedures for the development of this technique are presented. This methodology is being established by the nuclear and isotopic geology group of the IPEN. (author) [pt

  10. Comparative study on Charpy specimen reconstitution techniques

    International Nuclear Information System (INIS)

    Bourdiliau, B.; Decroix, G.-M.; Averty, X.; Wident, P.; Bienvenu, Y.

    2011-01-01

    Highlights: → Welding processes are used to reconstitute previously tested Charpy specimens. → Stud welding is preferred for a quick installation, almost immediately operational. → Friction welding produces better quality welds, but requires a development effort. - Abstract: Reconstitution techniques are often used to allow material from previously fractured Charpy-V specimens to be reused for additional experiments. This paper presents a comparative experimental study of various reconstitution techniques and evaluates the feasibility of these methods for future use in shielded cells. The following techniques were investigated: arc stud welding, 6.0 kW CO 2 continuous wave laser welding, 4.5 kW YAG continuous wave laser welding and friction welding. Subsize Charpy specimens were reconstituted using a 400 W YAG pulsed wave laser. The best result was obtained with arc stud welding; the resilience of the reconstituted specimens and the load-displacement curves agreed well with the reference specimens, and the temperature elevation caused by the welding process was limited to the vicinity of the weld. Good results were also obtained with friction welding; this process led to the best quality welds. Laser welding seems to have affected the central part of the specimens, thus leading to different resilience values and load-displacement curves.

  11. Impact of previously disadvantaged land-users on sustainable ...

    African Journals Online (AJOL)

    Impact of previously disadvantaged land-users on sustainable agricultural ... about previously disadvantaged land users involved in communal farming systems ... of input, capital, marketing, information and land use planning, with effect on ...

  12. The development of digital monitoring technique

    International Nuclear Information System (INIS)

    Koo, In Soo; Kim, D. H.; Kim, J. S.; Kim, C. H.; Kim, G. O.; Park, H. Y.; Suh, S. Y.; Sung, S. H.; Song, S. J.; Lee, C. K.; Jang, G. S.; Hur, S.

    1997-08-01

    A study has been performed for advanced DSP technology for the digital nuclear I and C systems for the monitoring and diagnosis techniques for high-pressurized structures integrity in NSSS. In the development of advanced DSP technology, real time process, communication network and signal validation were selected as the essential technologies of the digital signal process, and the requirements and methodology for the application of these technologies in NPP were established through technical analysis. Based on its results, the DPIS and the signal validation algorithm were developed. For the real-time process, the necessary requirements were define and the methodology of real-time software modeling was developed. For the communication network, the methodology of selection of the communication technique and developing procedure were established with an extraction of requirements. Functions, requirements, structure and technical specification were developed for the DPIS, and a real-time signal validation algorithm was developed and implemented for the signal validation. In a study on monitoring techniques for abnormal conditions, test and experimental facilities have been set up in order to carry out the required tests during research activities. Studies concentrated on how to acquire proper vibration or emission signals from mechanical structures and equipments, and to diagnose effectively the abnormal conditions of high pressure structure integrity. The algorithms of automatic signal analysis and diagnosis for abnormal conditions have been developed in this study to assist the operator's monitoring and diagnosis activities on structure integrity using new technologies. (author). 23 refs., 68 tabs., 196 figs

  13. The development of digital monitoring technique

    Energy Technology Data Exchange (ETDEWEB)

    Koo, In Soo; Kim, D. H.; Kim, J. S.; Kim, C. H.; Kim, G. O.; Park, H. Y.; Suh, S. Y.; Sung, S. H.; Song, S. J.; Lee, C. K.; Jang, G. S.; Hur, S.

    1997-08-01

    A study has been performed for advanced DSP technology for the digital nuclear I and C systems for the monitoring and diagnosis techniques for high-pressurized structures integrity in NSSS. In the development of advanced DSP technology, real time process, communication network and signal validation were selected as the essential technologies of the digital signal process, and the requirements and methodology for the application of these technologies in NPP were established through technical analysis. Based on its results, the DPIS and the signal validation algorithm were developed. For the real-time process, the necessary requirements were define and the methodology of real-time software modeling was developed. For the communication network, the methodology of selection of the communication technique and developing procedure were established with an extraction of requirements. Functions, requirements, structure and technical specification were developed for the DPIS, and a real-time signal validation algorithm was developed and implemented for the signal validation. In a study on monitoring techniques for abnormal conditions, test and experimental facilities have been set up in order to carry out the required tests during research activities. Studies concentrated on how to acquire proper vibration or emission signals from mechanical structures and equipments, and to diagnose effectively the abnormal conditions of high pressure structure integrity. The algorithms of automatic signal analysis and diagnosis for abnormal conditions have been developed in this study to assist the operator`s monitoring and diagnosis activities on structure integrity using new technologies. (author). 23 refs., 68 tabs., 196 figs.

  14. Experience of Delphi technique in the process of establishing consensus on core competencies.

    Science.gov (United States)

    Raghav, Pankaja Ravi; Kumar, Dewesh; Bhardwaj, Pankaj

    2016-01-01

    The Department of Community Medicine and Family Medicine (CMFM) has been started as a new model for imparting the components of family medicine and delivering health-care services at primary and secondary levels in all six newly established All India Institute of Medical Sciences (AIIMS), but there is no competency-based curriculum for it. The paper aims to share the experience of Delphi method in the process of developing consensus on core competencies of the new model of CMFM in AIIMS for undergraduate medical students in India. The study adopted different approaches and methods, but Delphi was the most critical method used in this research. In Delphi, the experts were contacted by e-mail and their feedback on the same was analyzed. Two rounds of Delphi were conducted in which 150 participants were contacted in Delphi-I but only 46 responded. In Delphi-II, 26 participants responded whose responses were finally considered for analysis. Three of the core competencies namely clinician, primary-care physician, and professionalism were agreed by all the participants, and the least agreement was observed in the competencies of epidemiologist and medical teacher. The experts having more experience were less consistent as responses were changed from agree to disagree in more than 15% of participants and 6% changed from disagree to agree. Within the given constraints, the final list of competencies and skills for the discipline of CMFM compiled after the Delphi process will provide a useful insight into the development of competency-based curriculum of the subject.

  15. Establishment of quality control technology for HTR fuel in Korea

    International Nuclear Information System (INIS)

    Lee, Young-Woo; Kim, Woong Ki; Kim, Yeon Ku; Cho, Moon Sung

    2009-01-01

    Korea is currently developing the HTR coated particle fuel technology in view of its long-term Nuclear Hydrogen Production Technology Development and Demonstration (NHDD) Project, which was launched in 2004, of an extensive R and D program on technology development for a hydrogen production by a VHTR. The current NHDD Project essentially covers the R and D works on the core and reactor system analysis, thermo-hydraulics and safety, coated particle fuel technology, material and component aspects and the hydrogen production technology by using the so-called Sulfur-Iodine Process (S-I Process). As a part of the NHDD Project, the fundamental technology for the coated particle fuel has been being developed, which consist of UO 2 kernel fabrication, pyrolytic carbon (PyC) and silicon carbide (SiC) coating technology, an in-reactor performance model development of a coated particle fuel and a preliminary preparative study for the irradiation tests of the coated particle fuel specimens in the HANARO reactor. In parallel with the development of fabrication process technology of the coated particle fuel, namely, kernel fabrication and coating processes, the characterization techniques for the important characteristics and quality control (QC) methods of the products after each process step were established. This paper deals with the works carried out for the development of the characterization technologies and establishment of the QC techniques for the coated fuel particles. Emphasis is given to the selection and development of the laboratory equipment and apparatus for the development of the methods of the characterizations and relevant QC methods

  16. The technological study on the decommissioning of nuclear facility, etc. in the Tokai Research Establishment

    International Nuclear Information System (INIS)

    Tomii, Hiroyuki; Matsuo, Kiyoshi; Shiraishi, Kunio; Kato, Rokuro; Watabe, Kozou; Higashiyama, Yutaka; Nagane, Satoru

    2005-03-01

    Since JPDR is dismantled and is removed, in Tokai Research Establishment, Japan Atomic Energy Research Institute, the dismantling of nuclear facility which finished the mission, etc. is advanced. At present, nuclear facility as a dismantling object count the approximately 20 facilities, and decommissioning plan of these facilities becomes an important problem, when the decommissioning countermeasure is considered. However, decommissioning techniques in proportion to various nuclear facility, etc. are clearly, and it has not been determined. In this report, the technical consideration on decommissioning techniques of nuclear facility promoted on the basis of this experience in future, while until now decommissioning experience and technical knowledge are arranged, etc. was added in order to appropriately and surely carry out decommissioning techniques and legal procedures, etc. (author)

  17. Introduction results of radiosurgery technique in cervical pathology consultation. Analysis of five years 2004 – 2009.

    Directory of Open Access Journals (Sweden)

    Rafael E. Pérez Castro

    2011-06-01

    Full Text Available AA cross sectional study and retrospective was performed in patients having cervical intraepithelial neoplasia (CIN, mainly in high grade lesions (CIN II, CIN III and C. In situ, which were treated with radiosurgery technique in the University General Hospital “Camilo Cienfuegos” Sancti Spiritus during the period may 2004 – may 2009 with the objective to evaluate the radiosurgery`s behaviour in the period mentioned before. The studied group was conformed by 550 patients having high grade lesions and low grade persistent lesions (NIC I with previous biopsy, a smaller group of 24 cases was formed by benign pathologies tributary of this procedure. High grade lesions were of major indications (73.1%. 69 cases were false negative (13.3%; since the second decade of life were presented high and low grade lesions of cervical pathology, a good correlation punch – cone byopsy was checked; edges of the surgical section behave properly, lower than what it is established in the international standard (6.7. The procedure had a great economic and social impact, because it is an ambulatory technique with few difficulties, low cost, and a fast integration patient – normal work.

  18. Isotopic Determination of Nuclear Materials Using Nuclear Fission Track Registration Technique and Thermal Ionization Mass Spectrometric Technique

    International Nuclear Information System (INIS)

    Jeon, Young Sin; Pyo, Hyeong Yeol; Park, Yong Joon; Song, Kyu Seok; Kim, Won Ho; Jee, Kwang Yong

    2007-05-01

    It is very important to develope the technology for the determination of isotopic ratios of hot particles( 234 U, 235 U, 236 U etc.) detected from swipe samples of various nuclear facilities. This technology is highly competitive internationally and has to be established independently as long as our government maintains atomic energy and treats nuclear materials. In this text, sample pretreatment procedure, gamma-ray counting, alpha or fission track techniques, isotopic analysis of U and Pu, background problems and detection limits for mass determination, and their application to the real swipe sample were described with detailed procedure. This technology would contribute to the Korean economy's high growth rate as well as to superiority of government's leading research and development programs if successfully established

  19. Radon remediation of dwellings with suspended timber floors -case studies from the Building Research Establishment (UK)

    International Nuclear Information System (INIS)

    Welsh, P.; Stephen, R.

    1994-01-01

    Dwellings with suspended floors and high radon levels are proving difficult to remediate. This paper reports on the experience of the Building Research Establishment in dealing with such dwellings. Brief details of the remediation of 14 houses are given, and comparisons are made between the effectiveness of the different techniques adopted. Natural ventilation, mechanical supply ventilation and mechanical extract ventilation are three techniques that have been used successfully as radon remedial measures. Preliminary results suggest that supply ventilation is more effective than extract ventilation. (author)

  20. A Secure Test Technique for Pipelined Advanced Encryption Standard

    Science.gov (United States)

    Shi, Youhua; Togawa, Nozomu; Yanagisawa, Masao; Ohtsuki, Tatsuo

    In this paper, we presented a Design-for-Secure-Test (DFST) technique for pipelined AES to guarantee both the security and the test quality during testing. Unlike previous works, the proposed method can keep all the secrets inside and provide high test quality and fault diagnosis ability as well. Furthermore, the proposed DFST technique can significantly reduce test application time, test data volume, and test generation effort as additional benefits.

  1. Intelligent techniques in engineering management theory and applications

    CERN Document Server

    Onar, Sezi

    2015-01-01

    This book presents recently developed intelligent techniques with applications and theory in the area of engineering management. The involved applications of intelligent techniques such as neural networks, fuzzy sets, Tabu search, genetic algorithms, etc. will be useful for engineering managers, postgraduate students, researchers, and lecturers. The book has been written considering the contents of a classical engineering management book but intelligent techniques are used for handling the engineering management problem areas. This comprehensive characteristics of the book makes it an excellent reference for the solution of complex problems of engineering management. The authors of the chapters are well-known researchers with their previous works in the area of engineering management.

  2. Mathematical pointing model establishment of the visual tracking theodolite for satellites in two kinds of observation methods.

    Science.gov (United States)

    Zhang, Yuncheng

    The mathematical pointing model is establishment of the visual tracking theodolite for satellites in two kinds of observation methods at Yunnan Observatory, which is related to the digitalisation reform and the optical-electronic technique reform, is introduced respectively in this paper.

  3. Effect of six different cooking techniques in the nutritional composition of two fish species previously selected as optimal for renal patient's diet.

    Science.gov (United States)

    Castro-González, Isabel; Maafs-Rodríguez, Ana Gabriela; Pérez-Gil Romo, Fernando

    2015-07-01

    Benefits of fish consumption are widely known, but there is little information about nutrient values of raw and cooked fish. The aim was to study the impact that six cooking techniques have on the nutritional composition of two fish species with low content of adverse nutrients in renal diet. Raw and steamed, foiled with aluminum, foiled with banana leaf, gas oven-baked, microwave oven-coked and fried lightly samples were chemically analyzed to determine their protein, phosphorus and lipid content. Crevalle jack: all methods increased lipid and protein content and fatty acids (FA) varied in all cooking methods. Phosphorus decreased in the steamed and microwave oven-cooked samples. Red drum: foiled and fried lightly increased lipid content compared to the raw sample. FA concentration changed in all cooking methods. Protein increased with every technique and phosphorus decreased in the steamed and gas oven-baked samples. Renal patients should preferably consume crevalle jack steamed or microwave oven-cooked and red drum steamed or gas oven-baked.

  4. Establishing and maintaining a satellite campus connected by synchronous video conferencing.

    Science.gov (United States)

    Fox, Brent I; McDonough, Sharon L; McConatha, Barry J; Marlowe, Karen F

    2011-06-10

    Pharmacy education has experienced substantial growth in the number of new schools and existing schools establishing satellite campuses. Several models have previously been used to connect primary and satellite campuses. We describe the Auburn University Harrison School of Pharmacy's (AUHSOP's) experiences using synchronous video conferencing between the Auburn University campus in Auburn and a satellite campus in Mobile, Alabama. We focus on the technology considerations related to planning, construction, implementation, and continued use of the various resources that support our program. Students' perceptions of their experiences related to technology also are described.

  5. Determining root correspondence between previously and newly detected objects

    Science.gov (United States)

    Paglieroni, David W.; Beer, N Reginald

    2014-06-17

    A system that applies attribute and topology based change detection to networks of objects that were detected on previous scans of a structure, roadway, or area of interest. The attributes capture properties or characteristics of the previously detected objects, such as location, time of detection, size, elongation, orientation, etc. The topology of the network of previously detected objects is maintained in a constellation database that stores attributes of previously detected objects and implicitly captures the geometrical structure of the network. A change detection system detects change by comparing the attributes and topology of new objects detected on the latest scan to the constellation database of previously detected objects.

  6. Establishment for Nuclear Equipment -Overview

    International Nuclear Information System (INIS)

    Pracz, J.

    2006-01-01

    Research and development works conducted in the Establishment for Nuclear Equipment (ZdAJ) were focused around 3 subject areas: an accelerator for cancer treatment, therapeutical tables, systems and methods for controlling objects that cross international borders. The new, medium energy accelerator for cancer therapy cases is being designed in the Establishment for several years. In 2005 progress was achieved. A physical part, containing an electron beam has been completed and the parameters of that beam make it useful for therapeutical purposes. Consequently, the work on designing and testing of beam control systems, ensuring its high stability, repetition of irradiation parameters and accuracy of dosage have been started. Results of these tests make it very probable that 2006 will be the final year of scientific works and in 2007 the new apparatus will be ready for sales. Therapeutical tables have become a leading product of ZdAJ IPJ. Their technical parameters, reliability and universality in uses are appreciated by many customers of ZdAJ. In 2005, the table Polkam 16 was registered by the national Office for Registration of Medical Equipment as the first product of ZdAJ that meets all technical and formal requirements of the safety mark CE. This allows sales of the product on the market of the European Union. The research and development part of designing a therapeutical table for uses in the total body irradiation technique was also concluded in 2005. After the September 11 terrorist attacks on WTC a matter of controlling international borders have become a priority for many countries. In 2005 in ZdAJ IPJ, we conducted many preliminary calculations and experiments analyzing systems of irradiation sources, both photon and neutron as well as systems of detection and designing of signals triggered by controlling objects crossing the border. The results so far have enabled us to formulate a research project which has been positively evaluated by experts and found

  7. High dose rate endobronchial brachytherapy - treatment technique

    International Nuclear Information System (INIS)

    Carvalho, Heloisa de Andrade; Aisen, Salim; Haddad, Cecilia Maria Kalil; Nadalin, Wladimir; Pedreira Junior, Wilson Leite; Chavantes, Maria Cristina

    1998-01-01

    High dose rate endobronchial brachytherapy is efficient in symptom relief due to obstructive endobronchial malignancies. However, it's role in survival improvement for patients with lung cancer is not yet established. The use of this treatment in increasing, specially in the developing countries. The purpose of this paper is to present the treatment technique used in the Radiotherapy Department of the Hospital da Clinicas, University of Sao Paulo, based on an experience of 60 cases treated with 180 procedures. Some practical suggestions and rules adopted in the Department are described. The severe complications rate is 6.7%, demonstrating an adequate patient selection associated with the technique utilized. (author)

  8. Screening and Establishment of Human Lung Cancer Cell Lines 
with Organ-specific Metastasis Potential

    Directory of Open Access Journals (Sweden)

    Qinghua ZHOU

    2014-03-01

    Full Text Available Background and objective Cancer metastasis is not only the malignant marker and characteristics, but also the main cause of failure to cure and lose their life in the patients with lung cancer. Lung cancer metastasis has organ-specific characteristics. The most common sites of lung cancer metastasis are mediastinal lymph node, brain, bone, liver and adrenal gland. The aim of this study is to screen and establish lung cancer cell model with organ-specific metastasis potential with human high-metastatic large cell lung cancer cell line L9981 established by our laboratory previously, and to provide cell models for studying the mechanisms and signal regulation of organ-specific metastasis of lung cancer. Materials and methods The parent lung cancer cell line, L9981-Luc, was inoculated in the armpit of nude mice. The live animal imaging system, IVIS-200, was used to detect the lung cancer organ-specific metastasis every week. When the organ-specific metastasis were established, the nude mices bearing the lung cancer were sacrificed when they became moribund. Under sterile conditions, the organs (mediastinal lymph nodes, lung, spinal column and brain with lung cancer organ-specific metastasis were removed and the metastasized nodules were dissected free of connective tissue and blood clots, and rinsed twice with medium. The metastasized nodules were finely minced using sterile scalpel blades in medium, and the cells were seeded in tissue culture dishes. Then, the cells with organ-specific metastasis potential were reinoculated into the armpit of nude mice, respectively. This processes were repeated to establish the organ-specific metastatic sublines of L9981-Luc cell line more than 10 times. Finally, the organ-specific metastasis sublines of L9981-Luc were screened and established, which the four cell lines have the characteristics only metastasized to brian, lung, bone and mediastinal lymph node. Results A group of organ-specific metastasis cell

  9. Trephine Transverse Colostomy Is Effective for Patients Who Have Previously Undergone Rectal Surgery

    Science.gov (United States)

    Yeom, Seung-Seop; Jung, Sung Woo; Oh, Se Heon; Lee, Jong Lyul; Yoon, Yong Sik; Park, In Ja; Lim, Seok-Byung; Yu, Chang Sik; Kim, Jin Cheon

    2018-01-01

    Purpose Colostomy creation is an essential procedure for colorectal surgeons, but the preferred method of colostomy varies by surgeon. We compared the outcomes of trephine colostomy creation with open those for the (laparotomy) and laparoscopic methods and evaluated appropriate indications for a trephine colostomy and the advantages of the technique. Methods We retrospectively evaluated 263 patients who had undergone colostomy creation by trephine, open and laparoscopic approaches between April 2006 and March 2016. We compared the clinical features and the operative and postoperative outcomes according to the approach used for stoma creation. Results One hundred sixty-three patients (62%) underwent colostomy surgery for obstructive causes and 100 (38%) for fistulous problems. The mean operative time was significantly shorter with the trephine approach (trephine, 46.0 ± 1.9 minutes; open, 78.7 ± 3.9 minutes; laparoscopic, 63.5 ± 5.0 minutes; P colostomy was feasible for a diversion colostomy (P colostomy is safe and can be implemented quickly in various situations, and compared to other colostomy procedures, the patient’s recovery is faster. Previous laparotomy history was not a contraindication for a trephine colostomy, and a trephine transverse colostomy is feasible for patients who have undergone previous rectal surgery. PMID:29742862

  10. Establishment of HeLa cell mutants deficient in sphingolipid-related genes using TALENs.

    Directory of Open Access Journals (Sweden)

    Toshiyuki Yamaji

    Full Text Available Sphingolipids are essential components in eukaryotes and have various cellular functions. Recent developments in genome-editing technologies have facilitated gene disruption in various organisms and cell lines. We here show the disruption of various sphingolipid metabolic genes in human cervical carcinoma HeLa cells by using transcription activator-like effector nucleases (TALENs. A TALEN pair targeting the human CERT gene (alternative name COL4A3BP encoding a ceramide transport protein induced a loss-of-function phenotype in more than 60% of HeLa cells even though the cell line has a pseudo-triploid karyotype. We have isolated several loss-of-function mutant clones for CERT, UGCG (encoding glucosylceramide synthase, and B4GalT5 (encoding the major lactosylceramide synthase, and also a CERT/UGCG double-deficient clone. Characterization of these clones supported previous proposals that CERT primarily contributes to the synthesis of SM but not GlcCer, and that B4GalT5 is the major LacCer synthase. These newly established sphingolipid-deficient HeLa cell mutants together with our previously established stable transfectants provide a 'sphingolipid-modified HeLa cell panel,' which will be useful to elucidate the functions of various sphingolipid species against essentially the same genomic background.

  11. Multiple-hook fixation in revision spinal deformity surgery for patients with a previous multilevel fusion mass: technical note and preliminary outcomes.

    Science.gov (United States)

    Liu, Ning; Wood, Kirkham B

    2017-03-01

    OBJECTIVE A previous multilevel fusion mass encountered during revision spinal deformity surgery may obscure anatomical landmarks, making instrumentation unworkable or incurring substantial blood loss and operative time. This study introduced a surgical technique of multiple-hook fixation for fixating previous multilevel fusion masses in revision spinal deformity surgeries and then evaluated its outcomes. METHODS Patients with a previous multilevel fusion mass who underwent revision corrective surgery down to the lumbosacral junction were retrospectively studied. Multiple hooks were used to fixate the fusion mass and linked to distal pedicle screws in the lumbosacral-pelvic complex. Radiological and clinical outcomes were evaluated. RESULTS The charts of 8 consecutive patients with spinal deformity were retrospectively reviewed (7 women, 1 man; mean age 56 years). The primary diagnoses included flat-back deformity (6 cases), thoracolumbar kyphoscoliosis (1 case), and lumbar spondylosis secondary to a previous scoliosis fusion (1 case). The mean follow-up duration was 30.1 months. Operations were performed at T3/4-ilium (4 cases), T7-ilium (1 case), T6-S1 (1 case), T12-S1 (1 case), and T9-L5 (1 case). Of 8 patients, 7 had sagittal imbalance preoperatively, and their mean C-7 plumb line improved from 10.8 ± 2.9 cm preoperatively to 5.3 ± 3.6 cm at final follow-up (p = 0.003). The mean lumbar lordosis of these patients at final follow-up was significantly greater than that preoperatively (35.2° ± 12.6° vs 16.8° ± 11.8°, respectively; p = 0.005). Two perioperative complications included osteotomy-related leg weakness in 1 patient and a stitch abscess in another. CONCLUSIONS The multiple-hook technique provides a viable alternative option for fixating a previous multilevel fusion mass in revision spinal deformity surgery.

  12. Market implications of advanced enrichment techniques

    International Nuclear Information System (INIS)

    Rougeau, J.-P.

    1987-01-01

    The only commercial outlet for uranium is for nuclear reactors and the uranium market will be closely linked to the nuclear power market for the forseeable future. Any production cost saving in the uranium cycle clearly, therefore, increases the chances for world-wide expansion of the nuclear industry. Thus, although there is overcapacity in enrichment, development of cheaper, new or more efficient established techniques, is important. The atomic vapour laser isotope separation process is considered and discussed against this background. Separative work units are explained for this technique. The problems of integrating laser isotope separation into the fuel cycle are discussed. The effects on the amount of natural uranium required for different recycling strategies, and for different laser tails assay and time schedules are illustrated. Over the next twenty years laser-based enrichment will have an important effect on the fuel cycle industry. COGEMA is expected to play a part in developing these new techniques. (U.K.)

  13. Early counterpulse technique applied to vacuum interrupters

    International Nuclear Information System (INIS)

    Warren, R.W.

    1979-11-01

    Interruption of dc currents using counterpulse techniques is investigated with vacuum interrupters and a novel approach in which the counterpulse is applied before contact separation. Important increases have been achieved in this way in the maximum interruptible current as well as large reductions in contact erosion. The factors establishing these new limits are presented and ways are discussed to make further improvements

  14. Process of establishing design requirements and selecting alternative configurations for conceptual design of a VLA

    Directory of Open Access Journals (Sweden)

    Bo-Young Bae

    2017-04-01

    Full Text Available In this study, a process for establishing design requirements and selecting alternative configurations for the conceptual phase of aircraft design has been proposed. The proposed process uses system-engineering-based requirement-analysis techniques such as objective tree, analytic hierarchy process, and quality function deployment to establish logical and quantitative standards. Moreover, in order to perform a logical selection of alternative aircraft configurations, it uses advanced decision-making methods such as morphological matrix and technique for order preference by similarity to the ideal solution. In addition, a preliminary sizing tool has been developed to check the feasibility of the established performance requirements and to evaluate the flight performance of the selected configurations. The present process has been applied for a two-seater very light aircraft (VLA, resulting in a set of tentative design requirements and two families of VLA configurations: a high-wing configuration and a low-wing configuration. The resulting set of design requirements consists of three categories: customer requirements, certification requirements, and performance requirements. The performance requirements include two mission requirements for the flight range and the endurance by reflecting the customer requirements. The flight performances of the two configuration families were evaluated using the sizing tool developed and the low-wing configuration with conventional tails was selected as the best baseline configuration for the VLA.

  15. Errorless discrimination established by differential autoshaping1

    Science.gov (United States)

    Wilkie, Donald M.; Ramer, Donald G.

    1974-01-01

    In Experiment I, pigeons exposed to a differential autoshaping procedure pecked a key in the presence of the stimulus associated with reinforcement but did not peck, or pecked infrequently, in the presence of the stimulus associated with nonreinforcement. In Experiment II, pigeons were exposed to a differential autoshaping procedure in which one stimulus was associated with reinforcement and two stimuli were associated with nonreinforcement. The birds initially responded in the presence of one stimulus associated with nonreinforcement but never responded in the presence of the second stimulus associated with nonreinforcement. They were subsequently exposed to an autoshaping procedure in which reinforcement followed both these stimuli. The number of stimulus-reinforcement pairings required to establish pecking in the presence of the stimulus during which responses had not previously occurred suggested that such stimuli are inhibitory. These findings have implications for autoshaping, errorless discrimination, inhibition, and theories of discrimination byproducts. PMID:16811797

  16. Establishing the Appropriate Attributes in Current Human Reliability Assessment Techniques for Nuclear Safety

    International Nuclear Information System (INIS)

    Bowie, Jane; Munley, Gary; Dang, Vinh; Wreathall, John; Bye, Andreas; Cooper, Susan; Marble, Julie; Peters, Sean; Xing, Jing; Fauchille, Veronique; Fiset, Jean Yves; Haage, Monica; Johanson, Gunnar; Jung, Won Dae; Kim, Jaewhan; Lee, Seung Jung; Kubicek, Jan; Le Bot, Pierre; Pesme, Helene; Preischl, Wolfgang; Salway, Alice; Amri, Abdallah; Lamarre, Greg; White, Andrew; )

    2015-03-01

    This report presents the results of a joint task of the Working Groups on Risk Assessment (WGRISK) and on Human and Organisational Factors (WGHOF) of the OECD/NEA CSNI, to identify desirable attributes of Human Reliability Assessment (HRA) methods, and to evaluate a range of HRA methods used in OECD member countries against those attributes. The purpose of this project is to provide information that will support regulators and operators of nuclear facilities when making judgements about the appropriateness of HRA methods for conducting assessments in support of Probabilistic Safety Assessments (PSA). The task was performed by an international team of Human Factors, HRA and PSA experts from a broad range of OECD member countries. As in other reviews of HRA methods, the study did not set out to recommend or promote the use of any particular HRA method. Rather the study aims to identify the strengths and limitations of commonly used and developing methods to aid those responsible for production of HRAs in selecting appropriate tools for specific HRA applications. The study also aims to assist regulators when making judgements on the appropriateness of the application of an HRA technique within nuclear-related probabilistic safety assessments. The report is aimed at practitioners in the field of human reliability assessment, human factors, and risk assessment more generally

  17. Establishment and application of a large calibration device of artificial radionuclide plane source

    International Nuclear Information System (INIS)

    Hu Mingkao; Zhang Jiyun; Wang Xinxing; Zhang Sheng

    2010-01-01

    With the expansion of the application fields of nuclear techniques and the development of economy, more and more airborne/vehicle and other large γ spectrometers are applied in the environment radiation monitoring of artificial radioactive nuclides. In order to ensure the reliability of the monitoring results, a large calibration device of artificial radionuclide plane source is established. The paper introduces the device's built history and the results of application. (authors)

  18. The establishment of implanted VX2 liver tumor model in rabbits and discussion on superselective left hepatic arterial catheterization with micro-catheter technique via femoral artery

    International Nuclear Information System (INIS)

    Jiang Xiongying; Luo Rongguang; Huang Jinhua; Miao Bijian; Wang Yan

    2011-01-01

    Objective: To establish the implanted VX2 liver tumor model in rabbits and to discuss the feasibility and technical features of superselective left hepatic arterial catheterization by using micro-catheter through the femoral artery catheter sheath. Methods: Forty New Zealand white rabbits were inoculated with fragments of VX2 tumor into the medial left lobe of liver by using a 16G lumbar puncture needle through laparotomy route. Two weeks later, all the rabbits were proved to be successfully inoculated with liver neoplasm on CT scanning. Then, the catheter sheath was inserted into one of the femoral arteries, which was followed by celiac artery angiography and left hepatic artery catheterization with a micro-catheter under DSA guidance in order to evaluate the main branches of celiac artery and the imaging manifestations of VX2 liver tumor. After that, some scheduled interventional experiments were carried out. Results: Imaging examination and histopathologic study showed that the successful rate of implanted rabbit VX2 liver tumor was 100% (40/40). And the successful rate of the catheter sheath inserted to femoral artery was 97.5% (39/40). The successful rate of celiac artery, gastro-hepatic artery, common hepatic artery, proper hepatic artery and left hepatic artery catheterizations was 100% (39/39), 100% (39/39), 100% (39/39), 94.9% (37/39) and 71.2% (28/39) respectively. Conclusion: To implant tumor tissue mass through laparotomy is a stable and reliable method to establish rabbit VX2 liver tumor model. The insertion of micro-catheter through rabbit femoral catheter sheath approach is a convenient and simple technique to be carried out for the left hepatic artery catheterization and it can efficiently solve the technical difficulties when performing the interventional treatment of the rabbit VX2 hepatic tumor via left hepatic artery approach. (authors)

  19. MODIFIED TECHNIQUE OF TOTAL LARYNGECTOMY

    Directory of Open Access Journals (Sweden)

    Predrag Spirić

    2010-12-01

    Full Text Available Surgical technique of total laryngectomy is well presented in many surgical textbooks. Essentially, it has remained the same since Gluck an Soerensen in 1922 described all its details. Generally, it stresses the U shape skin incision with releasing laryngeal structures and removing larynx from up to down. Further, pharyngeal reconstruction is performed with different kinds of sutures in two or more layers and is finished with skin suture and suction drainage. One of worst complications following this surgery is pharyngocutaneous fistula (PF. Modifications proposed in this this article suggests vertical skin incision with larynx removal from below upwards. In pharyngeal reconstruction we used the running locked suture in submucosal plan with „tobacco sac“ at the end on the tongue base instead of traditional T shaped suture. Suction drains were not used.The aim of study was to present the modified surgical technique of total laryingectomy and its impact on hospital stay duration and pharyngocutanous fistula formation. In this randomized study we analyzed 49 patients operated with modified surgical technique compared to 49 patient operated with traditional surgical technique of total laryngectomy. The modified technique of total laryngectomy was presented. Using modified technique we managed to decrease the PF percentage from previous 20,41% to acceptable 8,16% (p=0,0334. Also, the average hospital stay was shortened from 14,96 to 10,63 days (t =-2.9850; p=0.0358.The modified technique of total laryngectomy is safe, short and efficient surgical intervention which decreases the number of pharyngocutaneos fistulas and shortens the hospital stay.

  20. Objective techniques for psychological assessment, phase 2. [techniques for measuring human performance during space flight stress

    Science.gov (United States)

    Wortz, E. C.; Saur, A. J.; Nowlis, D. P.; Kendall, M. P.

    1974-01-01

    Results are presented of an initial experiment in a research program designed to develop objective techniques for psychological assessment of individuals and groups participating in long-duration space flights. Specifically examined is the rationale for utilizing measures of attention as an objective assessment technique. Subjects participating in the experiment performed various tasks (eg, playing matrix games which appeared on a display screen along with auditory stimuli). The psychophysiological reactions of the subjects were measured and are given. Previous research of various performance and psychophysiological methods of measuring attention is also discussed. The experiment design (independent and dependent variables) and apparatus (computers and display devices) are described and shown. Conclusions and recommendations are presented.

  1. Impacts of previous crops on Fusarium foot and root rot, and on yields of durum wheat in North West Tunisia

    Directory of Open Access Journals (Sweden)

    Samia CHEKALI

    2016-07-01

    Full Text Available The impacts of ten previous crop rotations (cereals, legumes and fallow on Fusarium foot and root rot of durum wheat were investigated for three cropping seasons in a trial established in 2004 in Northwest Tunisia. Fungi isolated from the roots and stem bases were identified using morphological and molecular methods, and were primarily Fusarium culmorum and F. pseudograminearum. Under low rainfall conditions, the previous crop affected F. pseudograminearum incidence on durum wheat roots but not F. culmorum. Compared to continuous cropping of durum wheat, barley as a previous crop increased disease incidence more than fivefold, while legumes and fallow tended to reduce incidence.  Barley as a previous crop increased wheat disease severity by 47%, compared to other rotations. Grain yield was negatively correlated with the incidence of F. culmorum infection, both in roots and stem bases, and fitted an exponential model (R2 = -0.61 for roots and -0.77 for stem bases, P<0.0001. Fusarium pseudograminearum was also negatively correlated with yield and fitted an exponential model (R2 = -0.53 on roots and -0.71 on stem bases, P < 0.0001 but was not correlated with severity.

  2. [Selective biopsy of the sentinel lymph node in patients with breast cancer and previous excisional biopsy: is there a change in the reliability of the technique according to time from surgery?].

    Science.gov (United States)

    Sabaté-Llobera, A; Notta, P C; Benítez-Segura, A; López-Ojeda, A; Pernas-Simon, S; Boya-Román, M P; Bajén, M T

    2015-01-01

    To assess the influence of time on the reliability of sentinel lymph node biopsy (SLNB) in breast cancer patients with previous excisional biopsy (EB), analyzing both the sentinel lymph node detection and the lymph node recurrence rate. Thirty-six patients with cT1/T2 N0 breast cancer and previous EB of the lesion underwent a lymphoscintigraphy after subdermal periareolar administration of radiocolloid, the day before SLNB. Patients were classified into two groups, one including 12 patients with up to 29 days elapsed between EB and SLNB (group A), and another with the remaining 24 in which time between both procedures was of 30 days or more (group B). Scintigraphic and surgical detection of the sentinel lymph node, histological status of the sentinel lymph node and of the axillary lymph node dissection, if performed, and lymphatic recurrences during follow-up, were analyzed. Sentinel lymph node visualization at the lymphoscintigraphy and surgical detection were 100% in both groups. Histologically, three patients showed macrometastasis in the sentinel lymph node, one from group A and two from group B. None of the patients, not even those with malignancy of the sentinel lymph node, relapsed after a medium follow-up of 49.5 months (24-75). Time elapsed between EB and SLNB does not influence the reliability of this latter technique as long as a superficial injection of the radiopharmaceutical is performed, proving a very high detection rate of the sentinel lymph node without evidence of lymphatic relapse during follow-up. Copyright © 2014 Elsevier España, S.L.U. and SEMNIM. All rights reserved.

  3. Typing DNA profiles from previously enhanced fingerprints using direct PCR.

    Science.gov (United States)

    Templeton, Jennifer E L; Taylor, Duncan; Handt, Oliva; Linacre, Adrian

    2017-07-01

    Fingermarks are a source of human identification both through the ridge patterns and DNA profiling. Typing nuclear STR DNA markers from previously enhanced fingermarks provides an alternative method of utilising the limited fingermark deposit that can be left behind during a criminal act. Dusting with fingerprint powders is a standard method used in classical fingermark enhancement and can affect DNA data. The ability to generate informative DNA profiles from powdered fingerprints using direct PCR swabs was investigated. Direct PCR was used as the opportunity to generate usable DNA profiles after performing any of the standard DNA extraction processes is minimal. Omitting the extraction step will, for many samples, be the key to success if there is limited sample DNA. DNA profiles were generated by direct PCR from 160 fingermarks after treatment with one of the following dactyloscopic fingerprint powders: white hadonite; silver aluminium; HiFi Volcano silk black; or black magnetic fingerprint powder. This was achieved by a combination of an optimised double-swabbing technique and swab media, omission of the extraction step to minimise loss of critical low-template DNA, and additional AmpliTaq Gold ® DNA polymerase to boost the PCR. Ninety eight out of 160 samples (61%) were considered 'up-loadable' to the Australian National Criminal Investigation DNA Database (NCIDD). The method described required a minimum of working steps, equipment and reagents, and was completed within 4h. Direct PCR allows the generation of DNA profiles from enhanced prints without the need to increase PCR cycle numbers beyond manufacturer's recommendations. Particular emphasis was placed on preventing contamination by applying strict protocols and avoiding the use of previously used fingerprint brushes. Based on this extensive survey, the data provided indicate minimal effects of any of these four powders on the chance of obtaining DNA profiles from enhanced fingermarks. Copyright © 2017

  4. CT colonography: Techniques, indications, findings

    International Nuclear Information System (INIS)

    Mang, Thomas; Graser, Anno; Schima, Wolfgang; Maier, Andrea

    2007-01-01

    Computed tomographic colonography (CTC) is a minimally invasive technique for imaging the entire colon. Based on a helical thin-section CT of the cleansed and air-distended colon, two-dimensional and three-dimensional projections are used for image interpretation. Several clinical improvements in patient preparation, technical advances in CT, and new developments in evaluation software have allowed CTC to develop into a powerful diagnostic tool. It is already well established as a reliable diagnostic tool in symptomatic patients. Many experts currently consider CTC a comparable alternative to conventional colonoscopy, although there is still debate about its sensitivity for the detection of colonic polyps in a screening population. This article summarizes the main indications, the current techniques in patient preparation, data acquisition and data analysis as well as imaging features for common benign and malignant colorectal lesions

  5. Preparation of Acrylamide-based Anionic Polyelectrolytes for Soil Establishment

    Directory of Open Access Journals (Sweden)

    Ahmad Rabiee

    2012-12-01

    Full Text Available Synthetic water soluble acrylamide-based polymers have wide range of ap-plications  in  the  feld  of  soil  establishment  and  non-desertifcation.  In  this research, the acrylamide-based anionic polyelectrolytes were prepared by  solution polymerization. The polymerization was carried out using AIBN as a radical initiator and at different degrees of anionic charges ranging between 10% and 30% using sodium hydroxide as hydrolyzing agents. The chemical structure of the  synthetic polymers was studied and confrmed by FTIR technique. The charge density on polymer backbone was determined by titration method. The rheological behavior of polymer solutions was evaluated by Brookfeld viscometer. The results show that the viscosity decreases with increasing the shear rate of solutions. Molecular weights of samples were measured by laser light scattering analyzer. The morphology of the polymer was studied by SEM and the EDX was used for elemental analysis determination. The anionic polymers with 10-30% negative charges were mixed with clay in order to evaluate the soil establishment. The results show that an anionic polyelectro-lyte can make soil particles more cohesive and improve soil physical properties.

  6. Erlotinib-induced rash spares previously irradiated skin

    International Nuclear Information System (INIS)

    Lips, Irene M.; Vonk, Ernest J.A.; Koster, Mariska E.Y.; Houwing, Ronald H.

    2011-01-01

    Erlotinib is an epidermal growth factor receptor inhibitor prescribed to patients with locally advanced or metastasized non-small cell lung carcinoma after failure of at least one earlier chemotherapy treatment. Approximately 75% of the patients treated with erlotinib develop acneiform skin rashes. A patient treated with erlotinib 3 months after finishing concomitant treatment with chemotherapy and radiotherapy for non-small cell lung cancer is presented. Unexpectedly, the part of the skin that had been included in his previously radiotherapy field was completely spared from the erlotinib-induced acneiform skin rash. The exact mechanism of erlotinib-induced rash sparing in previously irradiated skin is unclear. The underlying mechanism of this phenomenon needs to be explored further, because the number of patients being treated with a combination of both therapeutic modalities is increasing. The therapeutic effect of erlotinib in the area of the previously irradiated lesion should be assessed. (orig.)

  7. Economic Techniques of Occupational Health and Safety Management

    Science.gov (United States)

    Sidorov, Aleksandr I.; Beregovaya, Irina B.; Khanzhina, Olga A.

    2016-10-01

    The article deals with the issues on economic techniques of occupational health and safety management. Authors’ definition of safety management is given. It is represented as a task-oriented process to identify, establish and maintain such a state of work environment in which there are no possible effects of hazardous and harmful factors, or their influence does not go beyond certain limits. It was noted that management techniques that are the part of the control mechanism, are divided into administrative, organizational and administrative, social and psychological and economic. The economic management techniques are proposed to be classified depending on the management subject, management object, in relation to an enterprise environment, depending on a control action. Technoeconomic study, feasibility study, planning, financial incentives, preferential crediting of enterprises, pricing, profit sharing and equity, preferential tax treatment for enterprises, economic regulations and standards setting have been distinguished as economic techniques.

  8. Privacy-aware knowledge discovery novel applications and new techniques

    CERN Document Server

    Bonchi, Francesco

    2010-01-01

    Covering research at the frontier of this field, Privacy-Aware Knowledge Discovery: Novel Applications and New Techniques presents state-of-the-art privacy-preserving data mining techniques for application domains, such as medicine and social networks, that face the increasing heterogeneity and complexity of new forms of data. Renowned authorities from prominent organizations not only cover well-established results-they also explore complex domains where privacy issues are generally clear and well defined, but the solutions are still preliminary and in continuous development. Divided into seve

  9. Establishing a Statistical Link between Network Oscillations and Neural Synchrony.

    Directory of Open Access Journals (Sweden)

    Pengcheng Zhou

    2015-10-01

    Full Text Available Pairs of active neurons frequently fire action potentials or "spikes" nearly synchronously (i.e., within 5 ms of each other. This spike synchrony may occur by chance, based solely on the neurons' fluctuating firing patterns, or it may occur too frequently to be explicable by chance alone. When spike synchrony above chances levels is present, it may subserve computation for a specific cognitive process, or it could be an irrelevant byproduct of such computation. Either way, spike synchrony is a feature of neural data that should be explained. A point process regression framework has been developed previously for this purpose, using generalized linear models (GLMs. In this framework, the observed number of synchronous spikes is compared to the number predicted by chance under varying assumptions about the factors that affect each of the individual neuron's firing-rate functions. An important possible source of spike synchrony is network-wide oscillations, which may provide an essential mechanism of network information flow. To establish the statistical link between spike synchrony and network-wide oscillations, we have integrated oscillatory field potentials into our point process regression framework. We first extended a previously-published model of spike-field association and showed that we could recover phase relationships between oscillatory field potentials and firing rates. We then used this new framework to demonstrate the statistical relationship between oscillatory field potentials and spike synchrony in: 1 simulated neurons, 2 in vitro recordings of hippocampal CA1 pyramidal cells, and 3 in vivo recordings of neocortical V4 neurons. Our results provide a rigorous method for establishing a statistical link between network oscillations and neural synchrony.

  10. Establishment of Health Technology Assessment in Iran

    Directory of Open Access Journals (Sweden)

    Shila Doaee

    2012-06-01

    Full Text Available Objective: Health Technology Assessment (HTA aims at informing healthcare policymakers, managers and practitioners of the "clinical consequences, but also the economic, ethical, and other social implications of the diffusion and use of a specific procedure or technique on medical practice". So considering the policy-oriented nature of HTA that calls for a close integration into the functioning and governance of health systems the present study focuses on executive processes and function of the HTA office of Iran.Materials and methods: Data of this review study were collected through documented sources and observations from 2007 to 2010.Results: Health Technology Assessment began its activities as a secretariat in the Deputy of Health in 2007 and it continues as a Health Technology Assessment Office at the Management of Health Technology Assessment, Standardization, and Tariff at the Deputy of curative affairs of MOHME in the beginning of 2010.14 Technology of modern medical equipment and 8 pharmaceutical medicine are assessed, Now many of measures for HTA establishment  such as cooperation National Institute of Health Research (NIHR, Holding scientific committee meetings, Establishing  the  Master's degree of  health technology assessment ,Building capacities for health technology assessment through education in major universities of the country.Conclusion: pay attention to health technology assessment, selection and application of proper technologies in the frameworks of policy-making and managerial strategies and make efforts to develop it with the support of the governmental in Iran is necessary.

  11. Viscosity Meaurement Technique for Metal Fuels

    Energy Technology Data Exchange (ETDEWEB)

    Ban, Heng [Utah State Univ., Logan, UT (United States). Mechanical and Aerospace Engineering; Kennedy, Rory [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-02-09

    Metallic fuels have exceptional transient behavior, excellent thermal conductivity, and a more straightforward reprocessing path, which does not separate out pure plutonium from the process stream. Fabrication of fuel containing minor actinides and rare earth (RE) elements for irradiation tests, for instance, U-20Pu-3Am-2Np-1.0RE-15Zr samples at the Idaho National Laboratory, is generally done by melt casting in an inert atmosphere. For the design of a casting system and further scale up development, computational modeling of the casting process is needed to provide information on melt flow and solidification for process optimization. Therefore, there is a need for melt viscosity data, the most important melt property that controls the melt flow. The goal of the project was to develop a measurement technique that uses fully sealed melt sample with no Americium vapor loss to determine the viscosity of metallic melts and at temperatures relevant to the casting process. The specific objectives of the project were to: develop mathematical models to establish the principle of the measurement method, design and build a viscosity measurement prototype system based on the established principle, and calibrate the system and quantify the uncertainty range. The result of the project indicates that the oscillation cup technique is applicable for melt viscosity measurement. Detailed mathematical models of innovative sample ampoule designs were developed to not only determine melt viscosity, but also melt density under certain designs. Measurement uncertainties were analyzed and quantified. The result of this project can be used as the initial step toward the eventual goal of establishing a viscosity measurement system for radioactive melts.

  12. Viscosity Meaurement Technique for Metal Fuels

    International Nuclear Information System (INIS)

    Ban, Heng

    2015-01-01

    Metallic fuels have exceptional transient behavior, excellent thermal conductivity, and a more straightforward reprocessing path, which does not separate out pure plutonium from the process stream. Fabrication of fuel containing minor actinides and rare earth (RE) elements for irradiation tests, for instance, U-20Pu-3Am-2Np-1.0RE-15Zr samples at the Idaho National Laboratory, is generally done by melt casting in an inert atmosphere. For the design of a casting system and further scale up development, computational modeling of the casting process is needed to provide information on melt flow and solidification for process optimization. Therefore, there is a need for melt viscosity data, the most important melt property that controls the melt flow. The goal of the project was to develop a measurement technique that uses fully sealed melt sample with no Americium vapor loss to determine the viscosity of metallic melts and at temperatures relevant to the casting process. The specific objectives of the project were to: develop mathematical models to establish the principle of the measurement method, design and build a viscosity measurement prototype system based on the established principle, and calibrate the system and quantify the uncertainty range. The result of the project indicates that the oscillation cup technique is applicable for melt viscosity measurement. Detailed mathematical models of innovative sample ampoule designs were developed to not only determine melt viscosity, but also melt density under certain designs. Measurement uncertainties were analyzed and quantified. The result of this project can be used as the initial step toward the eventual goal of establishing a viscosity measurement system for radioactive melts.

  13. Utilisation of acoustic emission technique to monitor lubrication condition in a low speed bearing

    International Nuclear Information System (INIS)

    Nordin Jamaludin; Mohd Jailani Mohd Nor

    2003-01-01

    Monitoring of lubrication condition in rolling element bearings through the use of vibration analysis is an established technique. However, this success has not mirrored at low rotational speeds. At low speeds the energy generated from the poor lubricated bearing lubrication might not show as an obvious change in signature and thus become undetectable using conventional vibration measuring equipment. This paper presents an investigation into the applicability of acoustic emission technique and analysis for detecting poorly lubricated bearing rotating at a speed of 1.12 rpm. Investigations were centered on a test-rig designed to simulate the real bearing used in the field. The variation of lubricant amount in the low-speed bearing was successfully monitored using a new developed method known as pulse injection technique (PIT). The PIT technique was based on acoustic emission method. The technique involved transmitting a Dirac pulse to the test bearing via a transmitting acoustic emission sensor while the bearing was in operation. Analysing the captured acoustic emission signatures using established statistical method could differentiate between properly and poorly lubricated bearing. (Author)

  14. Proposed Methodology for Establishing Area of Applicability

    International Nuclear Information System (INIS)

    Broadhead, B.L.; Hopper, C.M.; Parks, C.V.

    1999-01-01

    This paper presents the application of sensitivity and uncertainty (S/U) analysis methodologies to the data validation tasks of a criticality safety computational study. The S/U methods presented are designed to provide a formal means of establishing the area (or range) of applicability for criticality safety data validation studies. The development of parameters that are analogous to the standard trending parameters form the key to the technique. These parameters are the so-called D parameters, which represent the differences by energy group of S/U-generated sensitivity profiles, and c parameters, which are the k correlation coefficients, each of which give information relative to the similarity between pairs of selected systems. The use of a Generalized Linear Least-Squares Methodology (GLLSM) tool is also described in this paper. These methods and guidelines are also applied to a sample validation for uranium systems with enrichments greater than 5 wt %

  15. Ethnomathematical research and drama in education techniques: developing a dialogue in a geometry class of 10th grade students

    Directory of Open Access Journals (Sweden)

    Charoula Stathopoulou

    2015-07-01

    Full Text Available Ethnomathematical research, together with digital technologies (WebQuest and Drama-in-Education (DiE techniques, can create a fruitful learning environment in a mathematics classroom—a hybrid/third space—enabling increased student participation and higher levels of cognitive engagement. This article examines how ethnomathematical ideas processed within the experiential environment established by the Drama-in-Education techniques challenged students‘ conceptions of the nature of mathematics, the ways in which students engaged with mathematics learning using mind and body, and the ‗dialogue‘ that was developed between the Discourse situated in a particular practice and the classroom Discourse of mathematics teaching. The analysis focuses on an interdisciplinary project based on an ethnomathematical study of a designing tradition carried out by the researchers themselves, involving a search for informal mathematics and the connections with context and culture; 10th grade students in a public school in Athens were introduced to the mathematics content via an original WebQuest based on this previous ethnomathematical study; Geometry content was further introduced and mediated using the Drama-in-Education (DiE techniques. Students contributed in an unfolding dialogue between formal and informal knowledge, renegotiating both mathematical concepts and their perception of mathematics as a discipline.

  16. Ethnomathematical research and drama in education techniques: developing a dialogue in a geometry class of 10th grade students

    Directory of Open Access Journals (Sweden)

    Charoula Stathopoulou

    2015-01-01

    Full Text Available Ethnomathematical research, together with digital technologies (WebQuest and Drama-in-Education (DiE techniques, can create a fruitful learning environment in a mathematics classroom—a hybrid/third space—enabling increased student participation and higher levels of cognitive engagement. This article examines how ethnomathematical ideas processed within the experiential environment established by the Drama-in-Education techniques challenged students‘ conceptions of the nature of mathematics, the ways in which students engaged with mathematics learning using mind and body, and the ‗dialogue‘ that was developed between the Discourse situated in a particular practice and the classroom Discourse of mathematics teaching. The analysis focuses on an interdisciplinary project based on an ethnomathematical study of a designing tradition carried out by the researchers themselves, involving a search for informal mathematics and the connections with context and culture; 10th grade students in a public school in Athens were introduced to the mathematics content via an original WebQuest based on this previous ethnomathematical study; Geometry content was further introduced and mediated using the Drama-in-Education (DiE techniques. Students contributed in an unfolding dialogue between formal and informal knowledge, renegotiating both mathematical concepts and their perception of mathematics as a discipline.

  17. Aortic root replacement after previous surgical intervention on the aortic valve, aortic root, or ascending aorta.

    Science.gov (United States)

    Kirsch, E W Matthias; Radu, N Costin; Mekontso-Dessap, Armand; Hillion, Marie-Line; Loisance, Daniel

    2006-03-01

    Aortic root replacement after a previous operation on the aortic valve, aortic root, or ascending aorta remains a major challenge. Records of 56 consecutive patients (44 men; mean age, 56.4 +/- 13.6 years) undergoing reoperative aortic root replacement between June 1994 and June 2005 were reviewed retrospectively. Reoperation was performed 9.4 +/- 6.7 years after the last cardiac operation. Indications for reoperation were true aneurysm (n = 14 [25%]), false aneurysm (n = 10 [18%]), dissection or redissection (n = 9 [16%]), structural or nonstructural valve dysfunction (n = 10 [18%]), prosthetic valve-graft infection (n = 12 [21%]), and miscellaneous (n = 1 [2%]). Procedures performed were aortic root replacement (n = 47 [84%]), aortic root replacement plus mitral valve procedure (n = 5 [9%]), and aortic root replacement plus arch replacement (n = 4 [7%]). In 14 (25%) patients coronary artery bypass grafting had to be performed unexpectedly during the same procedure or immediately after the procedure to re-establish coronary perfusion. Hospital mortality reached 17.9% (n = 10). Multivariate logistic regression analysis revealed the need for unplanned perioperative coronary artery bypass grafting as the sole independent risk factor for hospital death (P = .005). Actuarial survival was 83.8% +/- 4.9% at 1 month, 73.0% +/- 6.3% at 1 year, and 65.7% +/- 9.0% at 5 years after the operation. One patient had recurrence of endocarditis 6.7 months after the operation and required repeated homograft aortic root replacement. Reoperative aortic root replacement remains associated with a high postoperative mortality. The need to perform unplanned coronary artery bypass grafting during reoperative aortic root replacement is a major risk factor for hospital death. The optimal technique for coronary reconstruction in this setting remains to be debated.

  18. 76 FR 10583 - Priorities for Addressing Risks to the Reliability of the Bulk-Power System; Notice Establishing...

    Science.gov (United States)

    2011-02-25

    ... Addressing Risks to the Reliability of the Bulk- Power System; Notice Establishing Date for Comments On... regarding priorities for addressing risks to the reliability of the Bulk-Power System, as previously... Bulk-Power System, 76 FR 2369 (January 13, 2011), as supplemented by the Reliability Technical...

  19. Inventory of present verification techniques. Viewpoint of EURATOM

    International Nuclear Information System (INIS)

    Kloeckner, W.; Eecken, D. Van der; Gmelin, W.

    1998-01-01

    Starting from the role of Euratom as an established regional safeguards system, an overview is given of verification techniques currently practised by Euratom. In the stage-light of a rapidly changing and complex international safeguards scene, Euratom considers it has an important role to play. Having in mind the possibilities created by accelerating modern technology, recommendations are given for an enhanced use of technological means in safeguards. The viewpoint of Euratom is that the majority of methodologies and techniques in place may very well be copied to or used for a cut-off verification system currently under discussion

  20. Business-oriented prioritization: A novel graphical technique

    International Nuclear Information System (INIS)

    Pascual, R.; Del Castillo, G.; Louit, D.; Knights, P.

    2009-01-01

    Traditionally, Pareto analysis has been used to select the most critical components and failure modes of a system. A clear disadvantage of this technique is that it requires preselecting a single criterion to establish priorities. More recently, a graphical log-scatter diagram technique has been proposed. It considers three key performance indicators simultaneously: reliability (MTBF), maintainability (MTTR), and unavailability (D). This technique considers only times and does not include economical effects explicitly. This article extends both techniques to explicitly consider both direct and indirect costs to prioritize from the point of view of an asset manager or from a maintenance decision-maker, as required. Due to the economic-based approach of this article, cost discounting is also considered inside financial costs such as-but not limited to-reliability-related investments. Also, the results are displayed on simple and accessible graphs which make them particularly useful for conveying results to non-technical managers. The methodology is illustrated by analyzing a shovel from the copper mine industry, and it clearly shows how the proposed technique facilitates business oriented decisions and how they should change under different market conditions.

  1. Business-oriented prioritization: A novel graphical technique

    Energy Technology Data Exchange (ETDEWEB)

    Pascual, R. [Centro de Mineria, Pontificia Universidad Catolica de Chile, Av. Vicuna Mackenna 4860, Santiago (Chile)], E-mail: rpascual@ing.puc.cl; Del Castillo, G. [Department of Mechanical Engineering, Universidad de Chile, Casilla 2777, Santiago (Chile); Louit, D. [Komatsu Chile, Av. Americo Vespucio 0631, Quilicura, Santiago (Chile); Centro de Mineria, Pontificia Universidad Catolica de Chile, Av. Vicuna Mackenna 4860, Santiago (Chile); Knights, P. [Division of Mining Engineering, Faculty of Engineering, Architecture and Information Technology, The University of Queensland, St. Lucia, Brisbane, 4072 (Australia)

    2009-08-15

    Traditionally, Pareto analysis has been used to select the most critical components and failure modes of a system. A clear disadvantage of this technique is that it requires preselecting a single criterion to establish priorities. More recently, a graphical log-scatter diagram technique has been proposed. It considers three key performance indicators simultaneously: reliability (MTBF), maintainability (MTTR), and unavailability (D). This technique considers only times and does not include economical effects explicitly. This article extends both techniques to explicitly consider both direct and indirect costs to prioritize from the point of view of an asset manager or from a maintenance decision-maker, as required. Due to the economic-based approach of this article, cost discounting is also considered inside financial costs such as-but not limited to-reliability-related investments. Also, the results are displayed on simple and accessible graphs which make them particularly useful for conveying results to non-technical managers. The methodology is illustrated by analyzing a shovel from the copper mine industry, and it clearly shows how the proposed technique facilitates business oriented decisions and how they should change under different market conditions.

  2. Adhesion, friction, wear, and lubrication research by modern surface science techniques.

    Science.gov (United States)

    Keller, D. V., Jr.

    1972-01-01

    The field of surface science has undergone intense revitalization with the introduction of low-energy electron diffraction, Auger electron spectroscopy, ellipsometry, and other surface analytical techniques which have been sophisticated within the last decade. These developments have permitted submono- and monolayer structure analysis as well as chemical identification and quantitative analysis. The application of a number of these techniques to the solution of problems in the fields of friction, lubrication, and wear are examined in detail for the particular case of iron; and in general to illustrate how the accumulation of pure data will contribute toward the establishment of physiochemical concepts which are required to understand the mechanisms that are operational in friction systems. In the case of iron, LEED, Auger and microcontact studies have established that hydrogen and light-saturated organic vapors do not establish interfaces which prevent iron from welding, whereas oxygen and some oxygen and sulfur compounds do reduce welding as well as the coefficient of friction. Interpretation of these data suggests a mechanism of sulfur interaction in lubricating systems.

  3. AN ANALYSIS OF TRANSLATION TECHNIQUES IN THE ENGLISH VERSION OF ARRAHMAN SURAH

    Directory of Open Access Journals (Sweden)

    Farida Repelita Wati Kembaren

    2018-02-01

    Full Text Available The Holy Qur’an has been translated into many languages including English. However, different translator of the Holy Qur’an produces different English version of Al-Qur’an because every translator uses different translation techniques to translate Al-Qur’an. This study aims to compare the three English versions of Arrahman surah, and describe the most dominant translation techniques used by the three translators to translate the Holy Qur’an. Translation techniques proposed by Molina and Albir (2002, p.509-511 are used to analyze the data. The data for this study are words, phrases, and clauses in the 78 verses of Arrahman surah in Arabic and its three English versions translated by Maulawi Sher ‘Ali, Dr. Muhammad Taqi­ud­Din Al­Hilali and Dr. Muhammad Muhsin Khan, and Talal Itani. The result shows that there are four most dominant techniques used by the three translators in translating the Holy Qur’an; Adaptation, Amplification, Established Equivalent, and Literal Translation technique. The first and the second translator prefer to use Amplification to introduce details in brackets or footnotes, but the third translator prefers to use Established Equivalent to find a term or expression recognized (by dictionaries or language in use as an equivalent.

  4. Evaluation of the ''Sabana de Bogota'' aquifer using isotopes techniques

    International Nuclear Information System (INIS)

    Torres, E.; Jimenez, G.; Obando, E.; Sanchez, L.; Alayon, E.

    1987-01-01

    Groundwater from the Sabana de Bogota area was studied by means of isotopic techniques such as isotope analysis, injection of tracers for determination of hydrogeological parameters, velocity measurements using tracers. These results combined with the ones obtained by conventional techniques were used to determine recharge area, origin, equipotencial lines and direction of groundwater. The results show that a combined application of classical and nuclear methods may establish rather reasonable hydrogeological concepts without investing much time and money

  5. Assessment of drainage techniques for evacuation of chronic subdural hematoma

    DEFF Research Database (Denmark)

    Sjåvik, Kristin; Bartek, Jiri; Sagberg, Lisa Millgård

    2018-01-01

    OBJECTIVE Surgery for chronic subdural hematoma (CSDH) is one of the most common neurosurgical procedures. The benefit of postoperative passive subdural drainage compared with no drains has been established, but other drainage techniques are common, and their effectiveness compared with passive...

  6. Early counterpulse technique applied to vacuum interrupters

    International Nuclear Information System (INIS)

    Warren, R.W.

    1979-01-01

    Interruption of dc currents using counterpulse techniques is investigated with vacuum interrupters and a novel approach in which the counterpulse is applied before contact separation. Important increases have been achieved in this way in the maximum interruptible current and large reductions in contact erosion. The factors establishing these new limits are presented and ways are discussed to make further improvements to the maximum interruptible current

  7. Establishment and maintenance of threatened long snouted seahorse, Hippocampus guttulatus, broodstock in captivity

    OpenAIRE

    Planas, Miguel; Chamorro, Alexandro; Quintas, Patricia; Vilar, Antonio

    2008-01-01

    Knowledge on seahorses is generally scarce but has been increasing in recent years due to their conservation status. Seahorse culture is a quite recent activity in most countries attempting it, and captive breeding techniques are available only for some species. With the aim of contributing to the development of breeding in captivity for conservative purposes, captive broodstock of the European long-snouted seahorse (Hippocampus guttulatus) was established with 32 wild seahorses captured in G...

  8. A computational/directional solidification method to establish saddle points on the Mg-Al-Ca liquidus

    International Nuclear Information System (INIS)

    Cao Hongbo; Zhang Chuan; Zhu Jun; Cao Guoping; Kou Sindo; Schmid-Fetzer, Rainer; Chang, Y. Austin

    2008-01-01

    We established two saddle point maxima, L + α(Mg) + C14 and L + α(Mg) + C36, on the monovariant liquidus, calculated from a previously presented thermodynamic description, by characterizing the microstructures of several directionally solidified alloys in the near-solidification front zone, the mushy zone, and the steady-state zone using optical microscopy, scanning electron microscopy and transmission electron microscopy

  9. Automatic electromagnetic valve for previous vacuum

    International Nuclear Information System (INIS)

    Granados, C. E.; Martin, F.

    1959-01-01

    A valve which permits the maintenance of an installation vacuum when electric current fails is described. It also lets the air in the previous vacuum bomb to prevent the oil ascending in the vacuum tubes. (Author)

  10. Characterization of Natural Dyes and Traditional Korean Silk Fabric by Surface Analytical Techniques

    Directory of Open Access Journals (Sweden)

    Yeonhee Lee

    2013-05-01

    Full Text Available Time-of-flight secondary ion mass spectrometry (TOF-SIMS and X-ray photoelectron spectroscopy (XPS are well established surface techniques that provide both elemental and organic information from several monolayers of a sample surface, while also allowing depth profiling or image mapping to be carried out. The static TOF-SIMS with improved performances has expanded the application of TOF-SIMS to the study of a variety of organic, polymeric and biological materials. In this work, TOF-SIMS, XPS and Fourier Transform Infrared (FTIR measurements were used to characterize commercial natural dyes and traditional silk fabric dyed with plant extracts dyes avoiding the time-consuming and destructive extraction procedures necessary for the spectrophotometric and chromatographic methods previously used. Silk textiles dyed with plant extracts were then analyzed for chemical and functional group identification of their dye components and mordants. TOF-SIMS spectra for the dyed silk fabric showed element ions from metallic mordants, specific fragment ions and molecular ions from plant-extracted dyes. The results of TOF-SIMS, XPS and FTIR are very useful as a reference database for comparison with data about traditional Korean silk fabric and to provide an understanding of traditional dyeing materials. Therefore, this study shows that surface techniques are useful for micro-destructive analysis of plant-extracted dyes and Korean dyed silk fabric.

  11. Characterization of Natural Dyes and Traditional Korean Silk Fabric by Surface Analytical Techniques

    Science.gov (United States)

    Lee, Jihye; Kang, Min Hwa; Lee, Kang-Bong; Lee, Yeonhee

    2013-01-01

    Time-of-flight secondary ion mass spectrometry (TOF-SIMS) and X-ray photoelectron spectroscopy (XPS) are well established surface techniques that provide both elemental and organic information from several monolayers of a sample surface, while also allowing depth profiling or image mapping to be carried out. The static TOF-SIMS with improved performances has expanded the application of TOF-SIMS to the study of a variety of organic, polymeric and biological materials. In this work, TOF-SIMS, XPS and Fourier Transform Infrared (FTIR) measurements were used to characterize commercial natural dyes and traditional silk fabric dyed with plant extracts dyes avoiding the time-consuming and destructive extraction procedures necessary for the spectrophotometric and chromatographic methods previously used. Silk textiles dyed with plant extracts were then analyzed for chemical and functional group identification of their dye components and mordants. TOF-SIMS spectra for the dyed silk fabric showed element ions from metallic mordants, specific fragment ions and molecular ions from plant-extracted dyes. The results of TOF-SIMS, XPS and FTIR are very useful as a reference database for comparison with data about traditional Korean silk fabric and to provide an understanding of traditional dyeing materials. Therefore, this study shows that surface techniques are useful for micro-destructive analysis of plant-extracted dyes and Korean dyed silk fabric. PMID:28809257

  12. From gene manipulation to forest establishment: shoot cultures of woody plants can be a central tool

    Energy Technology Data Exchange (ETDEWEB)

    McCown, B.H.

    1985-05-01

    Establishing germplasm of woody plants in microculture as shoot cultures has proved to be an effective method of overcoming many of the obstacles in working with these crops. Shoot cultures eliminate the changes associated with seasonal growth cycles and phase change and put large plants into a more manageable form. Well-established shoot cultures are central to successful clonal propagation systems for forest trees as well as to genetic improvement based on the use of cellular techniques such as protoplast manipulation. The physiological basis as to why tissues from shoot cultures are so readily manipulated is not well understood.

  13. Novel information theory techniques for phonon spectroscopy

    International Nuclear Information System (INIS)

    Hague, J P

    2007-01-01

    The maximum entropy method (MEM) and spectral reverse Monte Carlo (SRMC) techniques are applied to the determination of the phonon density of states (PDOS) from heat-capacity data. The approach presented here takes advantage of the standard integral transform relating the PDOS with the specific heat at constant volume. MEM and SRMC are highly successful numerical approaches for inverting integral transforms. The formalism and algorithms necessary to carry out the inversion of specific heat curves are introduced, and where possible, I have concentrated on algorithms and experimental details for practical usage. Simulated data are used to demonstrate the accuracy of the approach. The main strength of the techniques presented here is that the resulting spectra are always physical: Computed PDOS is always positive and properly applied information theory techniques only show statistically significant detail. The treatment set out here provides a simple, cost-effective and reliable method to determine phonon properties of new materials. In particular, the new technique is expected to be very useful for establishing where interesting phonon modes and properties can be found, before spending time at large scale facilities

  14. The determination of acoustic reflection coefficients by using cepstral techniques, II: Extensions of the technique and considerations of accuracy

    Science.gov (United States)

    Bolton, J. S.; Gold, E.

    1986-10-01

    In a companion paper the cepstral technique for the measurement of reflection coefficients was described. In particular the concepts of extraction noise and extraction delay were introduced. They are considered further here, and, in addition, a means of extending the cepstral technique to accommodate surfaces having lengthy impulse responses is described. The character of extraction noise, a cepstral component which interferes with reflection measurements, is largely determined by the spectrum of the signal radiated from the source loudspeaker. Here the origin and effects of extraction noise are discussed and it is shown that inverse filtering techniques may be used to reduce extraction noise without making impractical demands of the electrical test signal or the source loudspeaker. The extraction delay, a factor which is introduced when removing the reflector impulse response from the power cepstrum, has previously been estimated by a cross-correlation technique. Here the importance of estimating the extraction delay accurately is emphasized by showing the effect of small spurious delays on the calculation of the normal impedance of a reflecting surface. The effects are shown to accord with theory, and it was found that the real part of the estimated surface normal impedance is very nearly maximized when the spurious delay is eliminated; this has suggested a new way of determining the extraction delay itself. Finally, the basic cepstral technique is suited only to the measurement of surfaces whose impulse responses are shorter than τ, the delay between the arrival of the direct and specularly reflected components at the measurement position. Here it is shown that this restriction can be eliminated, by using a process known as cepstral inversion, when the direct cepstrum has a duration less than τ and cepstral aliasing is insignificant. It is also possible to use this technique to deconvolve a signal from an echo sequence in the time domain, an operation

  15. The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination

    NARCIS (Netherlands)

    D.C. van Gent (Dik)

    1996-01-01

    textabstractV(D)J recombination requires a pair of signal sequences with spacer lengths of 12 and 23 base pairs. Cleavage by the RAG1 AND RAG2 proteins was previously shown to demand only a single signal sequence. Here, we established conditions where 12- and 23-spacer signal

  16. Establishing a community-wide DNA barcode library as a new tool for arctic research

    DEFF Research Database (Denmark)

    Wirta, H.; Várkonyi, G.; Rasmussen, C.

    2016-01-01

    DNA sequences offer powerful tools for describing the members and interactions of natural communities. In this study, we establish the to-date most comprehensive library of DNA barcodes for a terrestrial site, including all known macroscopic animals and vascular plants of an intensively studied...... area of the High Arctic, the Zackenberg Valley in Northeast Greenland. To demonstrate its utility, we apply the library to identify nearly 20 000 arthropod individuals from two Malaise traps, each operated for two summers. Drawing on this material, we estimate the coverage of previous morphology...... ongoing shifts in arctic communities and ecosystems. The DNA barcode library now established for Zackenberg offers new scope for such explorations, and for the detailed dissection of interspecific interactions throughout the community....

  17. Of Needles and Haystacks: Novel Techniques for Data-Rich Economic Forecasting Data-Rich Economic Forecasting

    NARCIS (Netherlands)

    P. Exterkate (Peter)

    2011-01-01

    textabstractThis thesis discusses various novel techniques for economic forecasting. The focus is on methods that exploit the information in large data sets effectively. Each of these methods is compared to established techniques for forecasting yields on U.S. Treasury Bills, housing prices,

  18. Development of a coating technique for inertial confinement fusion plastic targets

    International Nuclear Information System (INIS)

    Kubo, U.; Tsubakihara, H.

    1986-01-01

    Deuterated polystyrene as a target material offers several advantages over other polymers because of the following: (1) it is chemically and physically stable at ordinary conditions, (2) it can be easily formed into spherical shells, and (3) it has a very high fraction of D 2 /H 2 (above approx.99%). As in our previous studies, the fabrication method was basically a utilization of the emulsion technique. This method is well suited to mass-producing the polymer targets without microprocessing techniques. We have developed a fabrication method for single shell targets and an extension of this technique also enables us to fabricate double shell targets. This new method is faster and less labor intensive than previous techniques. The development of ICF experiments requires multilayer structure targets; we have developed, moreover, a new fabrication technique called the multicoating method. The polymer coating can be fabricated by the application of an emulsion technique. On the other hand, with metal coating, a nonelectroplating method was used, and nickel was employed as the coating metal. The thickness of the polymer coating layer can be controlled with the rotational speed of a stirrer in the emulsion. In the case of nickel coating, it is achieved by controlling the plating bath temperature and immersion time during the plating process. The experiment resulted in the development of a new technique for the fabrication of multilayer targets and low density, thick polymer-layer-coated targets

  19. Detection of breast cancer using advanced techniques of data mining with neural networks; Deteccion de cancer de mama usando tecnicas avanzadas de mineria de datos con redes neuronales

    Energy Technology Data Exchange (ETDEWEB)

    Ortiz M, J. A.; Celaya P, J. M.; Martinez B, M. R.; Solis S, L. O.; Castaneda M, R.; Garza V, I.; Martinez F, M.; Lopez H, Y.; Ortiz R, J. M. [Universidad Autonoma de Zacatecas, Av. Ramon Lopez Velarde 801, Col. Centro, 98000 Zacatecas, Zac. (Mexico)

    2016-10-15

    The breast cancer is one of the biggest health problems worldwide, is the most diagnosed cancer in women and prevention seems impossible since its cause is unknown, due to this; the early detection has a key role in the patient prognosis. In developing countries such as Mexico, where access to specialized health services is minimal, the regular clinical review is infrequent and there are not enough radiologists; the most common form of detection of breast cancer is through self-exploration, but this is only detected in later stages, when is already palpable. For these reasons, the objective of the present work is the creation of a system of computer assisted diagnosis (CAD x) using information analysis techniques such as data mining and advanced techniques of artificial intelligence, seeking to offer a previous medical diagnosis or a second opinion, as if it was a second radiologist in order to reduce the rate of mortality from breast cancer. In this paper, advances in the design of computational algorithms using computer vision techniques for the extraction of features derived from mammograms are presented. Using data mining techniques of data mining is possible to identify patients with a high risk of breast cancer. With the information obtained from the mammography analysis, the objective in the next stage will be to establish a methodology for the generation of imaging bio-markers to establish a breast cancer risk index for Mexican patients. In this first stage we present results of the classification of patients with high and low risk of suffering from breast cancer using neural networks. (Author)

  20. Men's health promotion interventions: what have we learned from previous programmes.

    Science.gov (United States)

    Robertson, Steve; Witty, Karl; Zwolinsky, Steve; Day, Rhiannon

    2013-11-01

    Concern persists in health-related literature about men's reduced life expectancy and higher premature death rates; this is often linked to difficulties in engaging with men as a client group. However, some innovative projects and programmes, often led by health visitors or other community based nurses, have developed successful health promotion work with men. This article collates existing tacit knowledge (previous learning) about men's health interventions by integrating interview data from nine practitioners who have established such initiatives with data from 35 men's health project reports to consider 'what works'. Five themes stood out as being significant across the data reviewed: using the right setting (often outside statutory services); ensuring the right approach (drawing on male-specific interests and language); actively listening to what local men say; appropriate training (initial and ongoing) for those involved in such work; and partnership working with local community groups, businesses and statutory service providers. While not a panacea for working with any and all men, these themes form a good basis for successful engagement with men and align well with what a recent review of health visitor interventions suggest works in helping bridge service provision-uptake gaps.

  1. Factors affecting spruce establishment and recruitment near western treeline, Alaska

    Science.gov (United States)

    Miller, A. E.; Sherriff, R.; Wilson, T. L.

    2015-12-01

    Regional warming and increases in tree growth are contributing to increased productivity near the western forest margin in Alaska. The effects of warming on seedling recruitment has received little attention, in spite of forecasted forest expansion near western treeline. Here, we used stand structure and environmental data from white spruce (Picea glauca) stands (n = 95) sampled across a longitudinal gradient to explore factors influencing white spruce growth, establishment and recruitment in southwest Alaska. Using tree-ring chronologies developed from a subset of the plots (n = 30), we estimated establishment dates and basal area increment (BAI) for trees of all age classes across a range of site conditions. We used GLMs (generalized linear models) to explore the relationship between tree growth and temperature in undisturbed, low elevation sites along the gradient, using BAI averaged over the years 1975-2000. In addition, we examined the relationship between growing degree days (GDD) and seedling establishment over the previous three decades. We used total counts of live seedlings, saplings and live and dead trees, representing four cohorts, to evaluate whether geospatial, climate, and measured plot covariates predicted abundance of the different size classes. We hypothesized that the relationship between abundance and longitude would vary by size class, and that this relationship would be mediated by growing season temperature. We found that mean BAI for trees in undisturbed, low elevation sites increased with July maximum temperature, and that the slope of the relationship with temperature changed with longitude (interaction significant with 90% confidence). White spruce establishment was positively associated with longer summers and/or greater heat accumulation, as inferred from GDD. Seedling, sapling and tree abundance were also positively correlated with temperature across the study area. The response to longitude was mixed, with smaller size classes

  2. Newly established ELISA for N-ERC/mesothelin improves diagnostic accuracy in patients with suspected pleural mesothelioma.

    Science.gov (United States)

    Sato, Tadashi; Suzuki, Yohei; Mori, Takanori; Maeda, Masahiro; Abe, Masaaki; Hino, Okio; Takahashi, Kazuhisa

    2014-10-01

    Pleural mesothelioma is an aggressive tumor, commonly caused by exposure to asbestos. The prognosis of mesothelioma remains disappointing despite multimodal treatment. We reported previously that N-ERC/mesothelin could be a useful biomarker for the early diagnosis of pleural mesothelioma and developed an enzyme-linked immunosorbent assay (ELISA) system for its detection. However, the reproducibility of our previous 7-16 ELISA system has been revealed to be unsatisfactory. To measure N-ERC/mesothelin more precisely, we developed a new 7-20 ELISA system. The subjects of this study were patients who were referred to our department with suspected pleural mesothelioma. The current study demonstrated that the newly established 7-20 ELISA system improved the sensitivity and specificity for diagnosing pleural mesothelioma compared with the previous system. Moreover, the 7-20 ELISA system showed better reproducibility and displayed the tendency of both higher sensitivity and higher specificity in plasma than in serum. Particularly for the epithelioid type, the area under the curve (AUC) and the diagnostic accuracy of N-ERC/mesothelin were excellent; the AUC was 0.91, the sensitivity was 0.95, and the specificity was 0.76 in plasma. In conclusion, assessment of N-ERC/mesothelin with our newly established 7-20 ELISA system is clinically useful for the precise diagnosis of pleural mesothelioma. © 2014 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

  3. Startup activities of established Finnish companies

    OpenAIRE

    Saalasti, Sini

    2016-01-01

    Established companies have collaborated with startups for decades in order to enhance their capabilities in technology and innovation. However, in the recent years, the changes in the business environment have induced established companies to increase their collaboration with startups. Thus, startup activities of established companies have become a timely phenomenon. This study explores the startup activities of established companies by analyzing all the activity established companies conduct...

  4. A study on the establishment of a nuclear regulators' association in the Northeast Asia

    International Nuclear Information System (INIS)

    Shin, Won Ky; Park, Y. S.; Lee, H. J.; Park, D. K.; Choi, K. S.; Park, C. H.; Hwang, S. C.; Do, K. S.; Choi, Y. S.

    2001-12-01

    It is desirable to make joint efforts among northeast countries in order to assure nuclear safety in northeast Asia where nuclear power development has been active. In this regard, through this study, it is developed the draft for the establishment of a regional cooperative mechanism in the field of nuclear safety regulation in this region. This will be utilized as a basic references to plan and conduct regional cooperation in the field of nuclear safety regulation in this region. Through this study, the status of multilateral cooperative mechanisms in nuclear safety field, domestic and international nuclear safety trends, and nuclear safety cooperation status in this region are investigated. Based on this investigation, the draft for the establishment of the Nuclear Regulators Meeting in the Northeast Asia (NUREMA) and its implementation plan are developed. If the NUREMA is successfully established and operated, it will serve as a central basis for exchanging regulatory related information, experience, and techniques, etc., which will strengthen domestic and regional nuclear safety. It is desirable to strengthen the MOST∼NNSA∼METI Tripartite Meeting on a step by step basis for the next few years (4 - 5 years) and finally establish a multilateral cooperative mechanism like NUREMA

  5. Development of tritium-handling technique

    International Nuclear Information System (INIS)

    Ohmura, Hiroshi; Hosaka, Akio; Okamoto, Takahumi

    1988-01-01

    The overview of developing activities for tritium-handling techniques in IHI are presented. To establish a fusion power plant, tritium handling is one of the key technologies. Recently in JAERI, conceptual design of FER (Fusion Experimental Reactor) has been carried out, and the FER system requires a processing system for a large amount of tritium. IHI concentrate on investigation of fuel gas purification, isotope separation and storage systems under contract with Toshiba Corporation. Design results of the systems and each components are reviewed. IHI has been developing fundamental handling techniques which are the ZrNi bed for hydrogen isotope storage and isotope separation by laser. The ZrNi bed with a tritium storage capacity of 1000 Ci has been constructed and recovery capability of the hydrogen isotope until 10 -4 Torr {0.013 Pa} was confirmed. In laser isotope separation, the optimum laser wave length has been determined. (author)

  6. Dosimetric methodology for extremities of individuals occupationally exposed to beta radiation using the optically stimulated luminescence technique

    International Nuclear Information System (INIS)

    Pinto, Teresa Cristina Nathan Outeiro

    2010-01-01

    A dosimetric methodology was established for the determination of extremity doses of individuals occupationally exposed to beta radiation, using Al 2 O 3 :C detectors and the optically stimulated luminescence (OSL) reader system microStar, Landauer. The main parts of the work were: characterization of the dosimetric material Al 2 O 3 :C using the OSL technique; establishment of the dose evaluation methodology; dose rate determination of beta radiation sources; application of the established method in a practical test with individuals occupationally exposed to beta radiation during a calibration simulation of clinical applicators; validation of the methodology by the comparison between the dose results of the practical test using the OSL and the thermoluminescence (TL) techniques. The results show that both the OSL Al-2O 3 :C detectors and the technique may be utilized for individual monitoring of extremities and beta radiation. (author)

  7. Treatment of peat bogs harvested by deep digging technique

    International Nuclear Information System (INIS)

    Hoernsten, L.

    1992-06-01

    The aim of this study is to describe how peat bogs harvested by deep digging technique can be treated after harvesting has come to an end. The study points out treatment methods, how the treatments are carried out and to indicate the most appropriate method of harvest for optimum results. Costs and benefits are calculated for the methods involving cultivation. The knowledge gained from traditional peat harvesting technique indicate forestry, energy wood production and establishment of ponds as possible alternatives. Energy grass cultivation and establishments of game parks have not been tested. but are assumed to be viable on suitable sites. Establishment of duck ponds are also possible, even though conditions for these are better on firm ground. In this study spruce is estimated to produce 200 cubic meters during 105 year whilst pine produces 300 cubic meters. Calculations for pine and spruce estimate costs of respectively 17000 and 18000 SEK per hectare after 105 years. Energy wood production is estimated to be 11.6 tons dry matter per hectare and year which gives a net cost of 19000 SEK per hectare. Similarly energy grass cultivation results in an average annual harvest of 6.5 ton dry matter and a cost of 59000 SEK per hectare. If the results are applied to three specific cases, then forest cultivation and establishment of ponds are possible in all cases. Neither energy wood nor energy grass are appropriate in any of the three regions. At the particular site for this study all methods mentioned are possible. Depending on whether draining leads to a high or low water table, the most appropriate course would be the establishment of a pond respectively a game park of forest cultivation. (59 refs., 12 tabs., 4 figs.)

  8. Establishment of selected acute pulmonary thromboembolism model in experimental sheep

    International Nuclear Information System (INIS)

    Fan Jihai; Gu Xiulian; Chao Shengwu; Zhang Peng; Fan Ruilin; Wang Li'na; Wang Lulu; Wang Ling; Li Bo; Chen Taotao

    2010-01-01

    Objective: To establish a selected acute pulmonary thromboembolism model in experimental sheep suitable for animal experiment. Methods: By using Seldinger's technique the catheter sheath was placed in both the femoral vein and femoral artery in ten sheep. Under C-arm DSA guidance the catheter was inserted through the catheter sheath into the pulmonary artery. Via the catheter appropriate amount of sheep autologous blood clots was injected into the selected pulmonary arteries. The selected acute pulmonary thromboembolism model was thus established. Pulmonary angiography was performed to check the results. The pulmonary arterial pressure, femoral artery pressure,heart rates and partial pressure of oxygen in arterial blood (PaO 2 ) were determined both before and after the treatment. The above parameters obtained after the procedure were compared with the recorded parameters measured before the procedure, and the sheep model quality was evaluated. Results: The baseline of pulmonary arterial pressure was (27.30 ± 9.58) mmHg,femoral artery pressure was (126.4 ± 13.72) mmHg, heart rate was (103 ± 15) bpm and PaO 2 was (87.7 ± 12.04) mmHg. Sixty minutes after the injection of (30 ± 5) ml thrombotic agglomerates, the pulmonary arterial pressures rose to (52 ± 49) mmHg, femoral artery pressures dropped to (100 ± 21) mmHg. The heart rates went up to (150 ± 26) bpm. The PaO 2 fell to (25.3 ± 11.2) mmHg. After the procedure the above parameters were significantly different from that measured before the procedure in all ten animals (P < 0.01). The pulmonary arteriography clearly demonstrated that the selected pulmonary arteries were successfully embolized. Conclusion: The anatomy of sheep's femoral veins,vena cava system, pulmonary artery and right heart system are suitable for the establishment of the catheter passage, for this reason, selected acute pulmonary thromboembolism model can be easily created in experimental sheep. The technique is feasible and the model

  9. Emerging Raman Applications and Techniques in Biomedical and Pharmaceutical Fields

    CERN Document Server

    Morris, Michael D

    2010-01-01

    The book presents the latest technological advances in Raman spectroscopy that are presently redrawing the landscape of many fields of biomedical and pharmaceutical R&D. Numerous examples are given to illustrate the application of the new methods and compared with established and related techniques. The book is suitable for both new researchers and practitioners in this area as well as for those familiar with the Raman technique but seeking to keep abreast of the latest dramatic advances in this field.

  10. Aircraft applications of fault detection and isolation techniques

    Science.gov (United States)

    Marcos Esteban, Andres

    In this thesis the problems of fault detection & isolation and fault tolerant systems are studied from the perspective of LTI frequency-domain, model-based techniques. Emphasis is placed on the applicability of these LTI techniques to nonlinear models, especially to aerospace systems. Two applications of Hinfinity LTI fault diagnosis are given using an open-loop (no controller) design approach: one for the longitudinal motion of a Boeing 747-100/200 aircraft, the other for a turbofan jet engine. An algorithm formalizing a robust identification approach based on model validation ideas is also given and applied to the previous jet engine. A general linear fractional transformation formulation is given in terms of the Youla and Dual Youla parameterizations for the integrated (control and diagnosis filter) approach. This formulation provides better insight into the trade-off between the control and the diagnosis objectives. It also provides the basic groundwork towards the development of nested schemes for the integrated approach. These nested structures allow iterative improvements on the control/filter Youla parameters based on successive identification of the system uncertainty (as given by the Dual Youla parameter). The thesis concludes with an application of Hinfinity LTI techniques to the integrated design for the longitudinal motion of the previous Boeing 747-100/200 model.

  11. Bi Input-extended Kalman filter based estimation technique for speed-sensorless control of induction motors

    International Nuclear Information System (INIS)

    Barut, Murat

    2010-01-01

    This study offers a novel extended Kalman filter (EKF) based estimation technique for the solution of the on-line estimation problem related to uncertainties in the stator and rotor resistances inherent to the speed-sensorless high efficiency control of induction motors (IMs) in the wide speed range as well as extending the limited number of states and parameter estimations possible with a conventional single EKF algorithm. For this aim, the introduced estimation technique in this work utilizes a single EKF algorithm with the consecutive execution of two inputs derived from the two individual extended IM models based on the stator resistance and rotor resistance estimation, differently from the other approaches in past studies, which require two separate EKF algorithms operating in a switching or braided manner; thus, it has superiority over the previous EKF schemes in this regard. The proposed EKF based estimation technique performing the on-line estimations of the stator currents, the rotor flux, the rotor angular velocity, and the load torque involving the viscous friction term together with the rotor and stator resistance is also used in the combination with the speed-sensorless direct vector control of IM and tested with simulations under the challenging 12 scenarios generated instantaneously via step and/or linear variations of the velocity reference, the load torque, the stator resistance, and the rotor resistance in the range of high and zero speed, assuming that the measured stator phase currents and voltages are available. Even under those variations, the performance of the speed-sensorless direct vector control system established on the novel EKF based estimation technique is observed to be quite good.

  12. Bi Input-extended Kalman filter based estimation technique for speed-sensorless control of induction motors

    Energy Technology Data Exchange (ETDEWEB)

    Barut, Murat, E-mail: muratbarut27@yahoo.co [Nigde University, Department of Electrical and Electronics Engineering, 51245 Nigde (Turkey)

    2010-10-15

    This study offers a novel extended Kalman filter (EKF) based estimation technique for the solution of the on-line estimation problem related to uncertainties in the stator and rotor resistances inherent to the speed-sensorless high efficiency control of induction motors (IMs) in the wide speed range as well as extending the limited number of states and parameter estimations possible with a conventional single EKF algorithm. For this aim, the introduced estimation technique in this work utilizes a single EKF algorithm with the consecutive execution of two inputs derived from the two individual extended IM models based on the stator resistance and rotor resistance estimation, differently from the other approaches in past studies, which require two separate EKF algorithms operating in a switching or braided manner; thus, it has superiority over the previous EKF schemes in this regard. The proposed EKF based estimation technique performing the on-line estimations of the stator currents, the rotor flux, the rotor angular velocity, and the load torque involving the viscous friction term together with the rotor and stator resistance is also used in the combination with the speed-sensorless direct vector control of IM and tested with simulations under the challenging 12 scenarios generated instantaneously via step and/or linear variations of the velocity reference, the load torque, the stator resistance, and the rotor resistance in the range of high and zero speed, assuming that the measured stator phase currents and voltages are available. Even under those variations, the performance of the speed-sensorless direct vector control system established on the novel EKF based estimation technique is observed to be quite good.

  13. The challenging image-guided abdominal mass biopsy: established and emerging techniques 'if you can see it, you can biopsy it'.

    Science.gov (United States)

    Sainani, Nisha I; Arellano, Ronald S; Shyn, Paul B; Gervais, Debra A; Mueller, Peter R; Silverman, Stuart G

    2013-08-01

    Image-guided percutaneous biopsy of abdominal masses is among the most commonly performed procedures in interventional radiology. While most abdominal masses are readily amenable to percutaneous biopsy, some may be technically challenging for a number of reasons. Low lesion conspicuity, small size, overlying or intervening structures, motion, such as that due to respiration, are some of the factors that can influence the ability and ultimately the success of an abdominal biopsy. Various techniques or technologies, such as choice of imaging modality, use of intravenous contrast and anatomic landmarks, patient positioning, organ displacement or trans-organ approach, angling CT gantry, triangulation method, real-time guidance with CT fluoroscopy or ultrasound, sedation or breath-hold, pre-procedural image fusion, electromagnetic tracking, and others, when used singularly or in combination, can overcome these challenges to facilitate needle placement in abdominal masses that otherwise would be considered not amenable to percutaneous biopsy. Familiarity and awareness of these techniques allows the interventional radiologist to expand the use of percutaneous biopsy in clinical practice, and help choose the most appropriate technique for a particular patient.

  14. Estimation of Alpine Skier Posture Using Machine Learning Techniques

    Directory of Open Access Journals (Sweden)

    Bojan Nemec

    2014-10-01

    Full Text Available High precision Global Navigation Satellite System (GNSS measurements are becoming more and more popular in alpine skiing due to the relatively undemanding setup and excellent performance. However, GNSS provides only single-point measurements that are defined with the antenna placed typically behind the skier’s neck. A key issue is how to estimate other more relevant parameters of the skier’s body, like the center of mass (COM and ski trajectories. Previously, these parameters were estimated by modeling the skier’s body with an inverted-pendulum model that oversimplified the skier’s body. In this study, we propose two machine learning methods that overcome this shortcoming and estimate COM and skis trajectories based on a more faithful approximation of the skier’s body with nine degrees-of-freedom. The first method utilizes a well-established approach of artificial neural networks, while the second method is based on a state-of-the-art statistical generalization method. Both methods were evaluated using the reference measurements obtained on a typical giant slalom course and compared with the inverted-pendulum method. Our results outperform the results of commonly used inverted-pendulum methods and demonstrate the applicability of machine learning techniques in biomechanical measurements of alpine skiing.

  15. The establishment of enteral nutrition with minimally-invasive interventional procedure under endoscopic or imaging guidance

    International Nuclear Information System (INIS)

    Li Feng; Cheng Yingsheng

    2010-01-01

    For patients unable to get the necessary nutrition orally, a variety of techniques,including surgical way, to make gastrostomy with tube placement have been employed. For recent years, gastrostomy and tube placement with the help of endoscopic guidance or percutaneous interventional management has been developed, which is superior to surgical procedure in minimizing injuries, decreasing cost and reducing complications. In certain clinical situations, both endoscopic method and interventional method can be employed. This paper aims to make a comprehensive review of the indications, techniques and skills, advantages and disadvantages of both the endoscopy-guided and the imaging-guided percutaneous gastrojejunostomy for the establishment of enteral nutrition. (authors)

  16. Tumescent Anethesia : A Useful Technique For Harvesting Split- Thickness Skin Graft

    Directory of Open Access Journals (Sweden)

    Saraf Sanjay

    2004-01-01

    Full Text Available Tumescent anesthesia is a now an established technique for regional anesthesia of the skin and the subcutaneous fatty tissue. The unsurpassed simplicity and safely of this procedure have opened up the gates for newer indications. We have employed this technique for harvesting split-thickness grafts in various conditions. We have found that this technique is extremely simple in which large areas can be anesthetized for harvesting split-thickness skin grafts safely. The good passive resistance achieved facilitates easy harvesting of split-thickness grafts along with minimal bleeding and long lasting pain relief. We found this to be an inexpensive, safe and simple technique with elimination of risks and expenses of general anesthesia.

  17. Group decision-making techniques for natural resource management applications

    Science.gov (United States)

    Coughlan, Beth A.K.; Armour, Carl L.

    1992-01-01

    This report is an introduction to decision analysis and problem-solving techniques for professionals in natural resource management. Although these managers are often called upon to make complex decisions, their training in the natural sciences seldom provides exposure to the decision-making tools developed in management science. Our purpose is to being to fill this gap. We present a general analysis of the pitfalls of group problem solving, and suggestions for improved interactions followed by the specific techniques. Selected techniques are illustrated. The material is easy to understand and apply without previous training or excessive study and is applicable to natural resource management issues.

  18. Establishing sustainable strategies in urban underground engineering.

    Science.gov (United States)

    Curiel-Esparza, Jorge; Canto-Perello, Julian; Calvo, Maria A

    2004-07-01

    Growth of urban areas, the corresponding increased demand for utility services and the possibility of new types of utility systems are overcrowding near surface underground space with urban utilities. Available subsurface space will continue to diminish to the point where utilidors (utility tunnels) may become inevitable. Establishing future sustainable strategies in urban underground engineering consists of the ability to lessen the use of traditional trenching. There is an increasing interest in utility tunnels for urban areas as a sustainable technique to avoid congestion of the subsurface. One of the principal advantages of utility tunnels is the substantially lower environmental impact compared with common trenches. Implementing these underground facilities is retarded most by the initial cost and management procedures. The habitual procedure is to meet problems as they arise in current practice. The moral imperative of sustainable strategies fails to confront the economic and political conflicts of interest. Municipal engineers should act as a key enabler in urban underground sustainable development.

  19. Novel MRI techniques in the assessment of dementia

    Energy Technology Data Exchange (ETDEWEB)

    Teipel, Stefan J. [Ludwig-Maximilian University, Dementia and Neuroimaging Section, Department of Psychiatry, Alzheimer Memorial Center, Munich (Germany); University Rostock, Department of Psychiatry, Rostock (Germany); Meindl, Thomas [Ludwig-Maximilian University, Department of Clinical Radiology, University Hospitals-Grosshadern, Munich (Germany); Grinberg, Lea [Departamento di Patologia da FMUSP, Sao Paulo (Brazil); Instituto Israelita de Ensino e Pesquisa Albert Einstein, Sao Paulo (Brazil); Heinsen, Helmut [University Wuerzburg, Morphological Brain Research Unit, Wuerzburg (Germany); Hampel, Harald [Ludwig-Maximilian University, Dementia and Neuroimaging Section, Department of Psychiatry, Alzheimer Memorial Center, Munich (Germany); The Adelaide and Meath Hospital, Incorporating The National Children' s Hospital and Trinity College Institute of Neuroscience, Discipline of Psychiatry, School of Medicine, Trinity College Dublin, Dublin (Ireland)

    2008-03-15

    Positive markers of Alzheimer's disease (AD) have been established in MRI that may allow early detection of AD in at-risk groups. In the near future, these markers will be of high relevance for the selection of at-risk subjects in secondary preventive trials. We describe the methodology and diagnostic value of manual volumetry of the hippocampus and entorhinal cortex, automated voxel-based morphometry, cortical thickness measurement, basal forebrain volumetry and deformation-based morphometry, implementing multivariate statistics and machine learning algorithms to improve group separation and prediction of AD in at-risk groups. We also describe the methodological basis and results obtained in AD using the recently developed technique of diffusion tensor-based morphometry (DTI). This technique gives access to the integrity of subcortical fibre systems in the human brain. The best established structural biomarker of AD to date is hippocampus volume that already has been implemented as secondary endpoint in clinical trials on disease modification in AD. Automated approaches will gain an increasing role as endpoints of clinical trials in the near future given the interest in these techniques expressed by the regulatory authorities. DTI is still a developing field where analysis techniques are presently being devised to make optimal use of the multivariate data. Data on changes of fibre tract in preclinical AD are still limited, but the first results are promising in respect to a further enhancement of diagnostic accuracy by combining MRI and DTI. Besides their diagnostic use, MRI and DTI will broaden our understanding of the pathophysiology of AD and the structural and functional basis of normal cognition. (orig.)

  20. Novel MRI techniques in the assessment of dementia

    International Nuclear Information System (INIS)

    Teipel, Stefan J.; Meindl, Thomas; Grinberg, Lea; Heinsen, Helmut; Hampel, Harald

    2008-01-01

    Positive markers of Alzheimer's disease (AD) have been established in MRI that may allow early detection of AD in at-risk groups. In the near future, these markers will be of high relevance for the selection of at-risk subjects in secondary preventive trials. We describe the methodology and diagnostic value of manual volumetry of the hippocampus and entorhinal cortex, automated voxel-based morphometry, cortical thickness measurement, basal forebrain volumetry and deformation-based morphometry, implementing multivariate statistics and machine learning algorithms to improve group separation and prediction of AD in at-risk groups. We also describe the methodological basis and results obtained in AD using the recently developed technique of diffusion tensor-based morphometry (DTI). This technique gives access to the integrity of subcortical fibre systems in the human brain. The best established structural biomarker of AD to date is hippocampus volume that already has been implemented as secondary endpoint in clinical trials on disease modification in AD. Automated approaches will gain an increasing role as endpoints of clinical trials in the near future given the interest in these techniques expressed by the regulatory authorities. DTI is still a developing field where analysis techniques are presently being devised to make optimal use of the multivariate data. Data on changes of fibre tract in preclinical AD are still limited, but the first results are promising in respect to a further enhancement of diagnostic accuracy by combining MRI and DTI. Besides their diagnostic use, MRI and DTI will broaden our understanding of the pathophysiology of AD and the structural and functional basis of normal cognition. (orig.)

  1. Revisiting renovascular imaging for renal sympathetic denervation: current techniques and applications

    Energy Technology Data Exchange (ETDEWEB)

    Pua, Uei; Tan, Cher Heng [Tan Tock Seng Hospital, Department of Diagnostic Radiology, Singapore (Singapore); Ho, Hee Hwa; Tan, Julian Ko Beng; Ong, Paul Jau Leong [Tan Tock Seng Hospital, Department of Cardiology, Singapore (Singapore)

    2014-08-28

    Renal sympathetic denervation (RDN) is an emerging technique in the treatment of resistant hypertension, most commonly performed using an endovascular approach. Clinical and anatomical criteria for RDN are well established and imaging plays an integral role in selecting patients with suitable anatomy, procedural planning and device selection. Nevertheless, the current body of literature surrounding imaging related to RDN remains limited. The purpose of this article is to illustrate the expectations and limitations of various imaging techniques, including Doppler ultrasound, CT angiography, MR angiography and newer techniques such as non-contrast MR angiography, in the context of RDN. (orig.)

  2. Revisiting renovascular imaging for renal sympathetic denervation: current techniques and applications

    International Nuclear Information System (INIS)

    Pua, Uei; Tan, Cher Heng; Ho, Hee Hwa; Tan, Julian Ko Beng; Ong, Paul Jau Leong

    2015-01-01

    Renal sympathetic denervation (RDN) is an emerging technique in the treatment of resistant hypertension, most commonly performed using an endovascular approach. Clinical and anatomical criteria for RDN are well established and imaging plays an integral role in selecting patients with suitable anatomy, procedural planning and device selection. Nevertheless, the current body of literature surrounding imaging related to RDN remains limited. The purpose of this article is to illustrate the expectations and limitations of various imaging techniques, including Doppler ultrasound, CT angiography, MR angiography and newer techniques such as non-contrast MR angiography, in the context of RDN. (orig.)

  3. Establishing politically feasible water markets: a multi-criteria approach.

    Science.gov (United States)

    Ballestero, Enrique; Alarcón, Silverio; García-Bernabeu, Ana

    2002-08-01

    A multiple criteria decision-making (MCDM) model to simulate the establishment of water markets is developed. The environment is an irrigated area governed by a non-profit agency, which is responsible for water production, allocation, and pricing. There is a traditional situation of historical rights, average-cost pricing for water allocation, large quantities of water used, and inefficiency. A market-oriented policy could be implemented by accounting for ecological and political objectives such as saving groundwater and safeguarding historical rights while promoting economic efficiency. In this paper, a problem is solved by compromise programming, a multi-criteria technique based on the principles of Simonian logic. The model is theoretically developed and applied to the Lorca region in Spain near the Mediterranean Sea.

  4. Establishing and maintaining international collaborative research teams: an autobiographical insight

    Directory of Open Access Journals (Sweden)

    T J Carr

    2013-07-01

    Full Text Available Despite the growing impetus for international collaborative research teams (ICRT, there are relatively few resources available to guide and support researchers through the processes of establishing and maintaining ICRTs. In particular, no articles were found that provided researchers’ firsthand accounts of being a member of such a team. Having access to such personal accounts can help both experienced and novice researchers learn more directly about what to expect, as well as the benefits, challenges, pitfalls, and success strategies for establishing and maintaining ICRTs. The authors used phenomenological autobiographical reflective journaling to capture their experiences as members of ICRTs. In this article we provide an overview of key themes that emerged from the analysis of our reflections as members of ICRTs. These themes include: benefits, challenges, and strategies for success. Our aim is to share our first-hand experiences of what it is like to establish and participate in ICRT. It is not our intention to provide readers with prescriptive guidelines on how to set up and maintain ICRTs. Every ICRT is unique and some of these ideas may or may not apply in every case. Instead, we are describing what worked for us, hoping that others may benefit from our experience. Consequently, we suggest that the focus of ICRT should be on the benefits thereof which promote and encourage interaction between disciplines, transfer of knowledge and techniques and personal and professional development. Keywords: international, collaborative, research, teams, interdisciplinary

  5. Development and application of the methodology to establish life extension and modernization plan of aged hydropower plants

    International Nuclear Information System (INIS)

    Kim, Jong Sung; Kwon, Hyuck Cheon; Song, Byung Hun; Kwon, Chang Seop

    2009-01-01

    This paper provides how to establish an integrated plan for LE (Life Extension) and MD (MoDernization) of aged hydropower plants. The methodology is developed through review of overseas/domestic LE/MD histories, investigation of the previous overseas methodologies and consideration of domestic practices. The methodology includes reviews of the various factors such as condition, operation and maintenance history, up-to-date technology, and economic benefit. In order to establish the life extension/modernization plan, the methodology is applied to the domestic aged hydropower plants. Finally, priority rankings and draft practice plans for LE/MD are derived.

  6. Nuclear techniques in medicine

    International Nuclear Information System (INIS)

    Basson, J.K.

    1984-01-01

    The use of nuclear techniques in medicine has, also in South Africa, increased enormously, especially as regards diagnosis and reseach. In 1983 in vivo tests with radioisotopes were carried out and also in vitro tests, mainly by radioimmunoassay. Therapy with open and sealed radioactive sources was concentrated mainly on cancer treatments. In 1983 NUCOR supported 83 research projects in the life sciences. Imaging of organs or tissues in the body with nuclear techniques has developed into the most important application of nuclear medicine, with the development of even more specific labelled compounds as the main objective. Radioimmunoassay is at an exciting watershed, now that labelled monoclonal antibodies with high specificity for early diagnosis (also in cancer) and even localised radiotherapy have become available. The establishment of the 200 MeV open-sector cyclotron by the National Accelerator Centre also for medical purposes will, in addition to the large-scale production of the protonrich isotopes, also make a substantial contribution to radiotherapy with nuclear particles such as neutrons, protons and helium-3

  7. Jet-images: computer vision inspired techniques for jet tagging

    Energy Technology Data Exchange (ETDEWEB)

    Cogan, Josh; Kagan, Michael; Strauss, Emanuel; Schwarztman, Ariel [SLAC National Accelerator Laboratory,Menlo Park, CA 94028 (United States)

    2015-02-18

    We introduce a novel approach to jet tagging and classification through the use of techniques inspired by computer vision. Drawing parallels to the problem of facial recognition in images, we define a jet-image using calorimeter towers as the elements of the image and establish jet-image preprocessing methods. For the jet-image processing step, we develop a discriminant for classifying the jet-images derived using Fisher discriminant analysis. The effectiveness of the technique is shown within the context of identifying boosted hadronic W boson decays with respect to a background of quark- and gluon-initiated jets. Using Monte Carlo simulation, we demonstrate that the performance of this technique introduces additional discriminating power over other substructure approaches, and gives significant insight into the internal structure of jets.

  8. Jet-images: computer vision inspired techniques for jet tagging

    International Nuclear Information System (INIS)

    Cogan, Josh; Kagan, Michael; Strauss, Emanuel; Schwarztman, Ariel

    2015-01-01

    We introduce a novel approach to jet tagging and classification through the use of techniques inspired by computer vision. Drawing parallels to the problem of facial recognition in images, we define a jet-image using calorimeter towers as the elements of the image and establish jet-image preprocessing methods. For the jet-image processing step, we develop a discriminant for classifying the jet-images derived using Fisher discriminant analysis. The effectiveness of the technique is shown within the context of identifying boosted hadronic W boson decays with respect to a background of quark- and gluon-initiated jets. Using Monte Carlo simulation, we demonstrate that the performance of this technique introduces additional discriminating power over other substructure approaches, and gives significant insight into the internal structure of jets.

  9. Steganalysis Techniques for Documents and Images

    Science.gov (United States)

    2005-05-01

    steganography . We then illustrated the efficacy of our model using variations of LSB steganography . For binary images , we have made significant progress in...efforts have focused on two areas. The first area is LSB steganalysis for grayscale images . Here, as we had proposed (as a challenging task), we have...generalized our previous steganalysis technique of sample pair analysis to a theoretical framework for the detection of the LSB steganography . The new

  10. Basalt identification by interpreting nuclear and electrical well logging measurements using fuzzy technique (case study from southern Syria)

    International Nuclear Information System (INIS)

    Asfahani, J.; Abdul Ghani, B.; Ahmad, Z.

    2015-01-01

    Fuzzy analysis technique is proposed in this research for interpreting the combination of nuclear and electrical well logging data, which include natural gamma ray, density and neutron-porosity, while the electrical well logging include long and short normal. The main objective of this work is to describe, characterize and establish the lithology of the large extended basaltic areas in southern Syria. Kodana well logging measurements have been used and interpreted for testing and applying the proposed technique. The established lithological cross section shows the distribution and the identification of four kinds of basalt, which are hard massive basalt, hard basalt, pyroclastic basalt and the alteration basalt products, clay. The fuzzy analysis technique is successfully applied on the Kodana well logging data, and can be therefore utilized as a powerful tool for interpreting huge well logging data with higher number of variables required for lithological estimations. - Highlights: • Apply fuzzy analysis technique on the nuclear and electrical well logging data of Kodana well in Southern Syria. • Determine and differentiate between four kinds of basalt. • Establish the lithological section of the studied well.

  11. Emotional Freedom Techniques for Anxiety: A Systematic Review With Meta-analysis.

    Science.gov (United States)

    Clond, Morgan

    2016-05-01

    Emotional Freedom Technique (EFT) combines elements of exposure and cognitive therapies with acupressure for the treatment of psychological distress. Randomized controlled trials retrieved by literature search were assessed for quality using the criteria developed by the American Psychological Association's Division 12 Task Force on Empirically Validated Treatments. As of December 2015, 14 studies (n = 658) met inclusion criteria. Results were analyzed using an inverse variance weighted meta-analysis. The pre-post effect size for the EFT treatment group was 1.23 (95% confidence interval, 0.82-1.64; p freedom technique treatment demonstrated a significant decrease in anxiety scores, even when accounting for the effect size of control treatment. However, there were too few data available comparing EFT to standard-of-care treatments such as cognitive behavioral therapy, and further research is needed to establish the relative efficacy of EFT to established protocols.

  12. Efficacy of gamma sterilization technique for biofertilizer carrier production

    International Nuclear Information System (INIS)

    Rallos, Roland V.; Rivera, Faye G.; Anarna, Julie A.; Rojales, Jacqueline S.

    2013-01-01

    Th use of gamma irradiation as sterilization technique for biofertilizer carrier is very efficient and practical especially in large scale production. The results of this study on the efficacy of gamma sterilization justify research on the effects of established doses of gamma irradiation on the physico-chemical properties of the clay-charcoal mixture

  13. Recent advances on Charpy specimen reconstitution techniques

    Energy Technology Data Exchange (ETDEWEB)

    Andrade, Arnaldo H.P.; Lobo, Raquel M.; Miranda, Carlos Alexandre J., E-mail: aandrade@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2017-07-01

    Charpy specimen reconstitution is widely used around the world as a tool to enhance or supplement surveillance programs of nuclear reactor pressure vessels. The reconstitution technique consists in the incorporation of a small piece from a previously tested specimen into a compound specimen, allowing to increase the number of tests. This is especially important if the available materials is restricted and fracture mechanics parameter have to be determined. The reconstitution technique must fulfill some demands, among them tests results like the original standard specimens and the loaded material of the insert must not be influenced by the welding and machining procedure. It is known that reconstitution of Charpy specimens may affect the impact energy in a consequence of the constraint of plastic deformation by the hardened weldment and HAZ. This paper reviews some recent advances of the reconstitution technique and its applications. (author)

  14. Recent advances on Charpy specimen reconstitution techniques

    International Nuclear Information System (INIS)

    Andrade, Arnaldo H.P.; Lobo, Raquel M.; Miranda, Carlos Alexandre J.

    2017-01-01

    Charpy specimen reconstitution is widely used around the world as a tool to enhance or supplement surveillance programs of nuclear reactor pressure vessels. The reconstitution technique consists in the incorporation of a small piece from a previously tested specimen into a compound specimen, allowing to increase the number of tests. This is especially important if the available materials is restricted and fracture mechanics parameter have to be determined. The reconstitution technique must fulfill some demands, among them tests results like the original standard specimens and the loaded material of the insert must not be influenced by the welding and machining procedure. It is known that reconstitution of Charpy specimens may affect the impact energy in a consequence of the constraint of plastic deformation by the hardened weldment and HAZ. This paper reviews some recent advances of the reconstitution technique and its applications. (author)

  15. Secondary recurrent miscarriage is associated with previous male birth.

    LENUS (Irish Health Repository)

    Ooi, Poh Veh

    2012-01-31

    Secondary recurrent miscarriage (RM) is defined as three or more consecutive pregnancy losses after delivery of a viable infant. Previous reports suggest that a firstborn male child is associated with less favourable subsequent reproductive potential, possibly due to maternal immunisation against male-specific minor histocompatibility antigens. In a retrospective cohort study of 85 cases of secondary RM we aimed to determine if secondary RM was associated with (i) gender of previous child, maternal age, or duration of miscarriage history, and (ii) increased risk of pregnancy complications. Fifty-three women (62.0%; 53\\/85) gave birth to a male child prior to RM compared to 32 (38.0%; 32\\/85) who gave birth to a female child (p=0.002). The majority (91.7%; 78\\/85) had uncomplicated, term deliveries and normal birth weight neonates, with one quarter of the women previously delivered by Caesarean section. All had routine RM investigations and 19.0% (16\\/85) had an abnormal result. Fifty-seven women conceived again and 33.3% (19\\/57) miscarried, but there was no significant difference in failure rates between those with a previous male or female child (13\\/32 vs. 6\\/25, p=0.2). When patients with abnormal results were excluded, or when women with only one previous child were considered, there was still no difference in these rates. A previous male birth may be associated with an increased risk of secondary RM but numbers preclude concluding whether this increases recurrence risk. The suggested association with previous male birth provides a basis for further investigations at a molecular level.

  16. Secondary recurrent miscarriage is associated with previous male birth.

    LENUS (Irish Health Repository)

    Ooi, Poh Veh

    2011-01-01

    Secondary recurrent miscarriage (RM) is defined as three or more consecutive pregnancy losses after delivery of a viable infant. Previous reports suggest that a firstborn male child is associated with less favourable subsequent reproductive potential, possibly due to maternal immunisation against male-specific minor histocompatibility antigens. In a retrospective cohort study of 85 cases of secondary RM we aimed to determine if secondary RM was associated with (i) gender of previous child, maternal age, or duration of miscarriage history, and (ii) increased risk of pregnancy complications. Fifty-three women (62.0%; 53\\/85) gave birth to a male child prior to RM compared to 32 (38.0%; 32\\/85) who gave birth to a female child (p=0.002). The majority (91.7%; 78\\/85) had uncomplicated, term deliveries and normal birth weight neonates, with one quarter of the women previously delivered by Caesarean section. All had routine RM investigations and 19.0% (16\\/85) had an abnormal result. Fifty-seven women conceived again and 33.3% (19\\/57) miscarried, but there was no significant difference in failure rates between those with a previous male or female child (13\\/32 vs. 6\\/25, p=0.2). When patients with abnormal results were excluded, or when women with only one previous child were considered, there was still no difference in these rates. A previous male birth may be associated with an increased risk of secondary RM but numbers preclude concluding whether this increases recurrence risk. The suggested association with previous male birth provides a basis for further investigations at a molecular level.

  17. The importance of establishing an international network of tissue banks and regional tissue processing centers.

    Science.gov (United States)

    Morales Pedraza, Jorge

    2014-03-01

    During the past four decades, many tissue banks have been established across the world with the aim of supplying sterilized tissues for clinical use and research purposes. Between 1972 and 2005, the International Atomic Energy Agency supported the establishment of more than sixty of these tissue banks in Latin America and the Caribbean, Asia and the Pacific, Africa and Eastern Europe; promoted the use of the ionizing radiation technique for the sterilization of the processed tissues; and encouraged cooperation between the established tissue banks during the implementation of its program on radiation and tissue banking at national, regional and international levels. Taking into account that several of the established tissue banks have gained a rich experience in the procurement, processing, sterilization, storage, and medical use of sterilized tissues, it is time now to strengthen further international and regional cooperation among interested tissue banks located in different countries. The purpose of this cooperation is to share the experience gained by these banks in the procurement, processing, sterilization, storage, and used of different types of tissues in certain medical treatments and research activities. This could be done through the establishment of a network of tissue banks and a limited number of regional tissue processing centers in different regions of the world.

  18. Establishment of Approximate Analytical Model of Oil Film Force for Finite Length Tilting Pad Journal Bearings

    Directory of Open Access Journals (Sweden)

    Yongliang Wang

    2015-01-01

    Full Text Available Tilting pad bearings offer unique dynamic stability enabling successful deployment of high-speed rotating machinery. The model of dynamic stiffness, damping, and added mass coefficients is often used for rotordynamic analyses, and this method does not suffice to describe the dynamic behaviour due to the nonlinear effects of oil film force under larger shaft vibration or vertical rotor conditions. The objective of this paper is to present a nonlinear oil force model for finite length tilting pad journal bearings. An approximate analytic oil film force model was established by analysing the dynamic characteristic of oil film of a single pad journal bearing using variable separation method under the dynamic π oil film boundary condition. And an oil film force model of a four-tilting-pad journal bearing was established by using the pad assembly technique and considering pad tilting angle. The validity of the model established was proved by analyzing the distribution of oil film pressure and the locus of journal centre for tilting pad journal bearings and by comparing the model established in this paper with the model established using finite difference method.

  19. Security Techniques for the Electronic Health Records.

    Science.gov (United States)

    Kruse, Clemens Scott; Smith, Brenna; Vanderlinden, Hannah; Nealand, Alexandra

    2017-08-01

    The privacy of patients and the security of their information is the most imperative barrier to entry when considering the adoption of electronic health records in the healthcare industry. Considering current legal regulations, this review seeks to analyze and discuss prominent security techniques for healthcare organizations seeking to adopt a secure electronic health records system. Additionally, the researchers sought to establish a foundation for further research for security in the healthcare industry. The researchers utilized the Texas State University Library to gain access to three online databases: PubMed (MEDLINE), CINAHL, and ProQuest Nursing and Allied Health Source. These sources were used to conduct searches on literature concerning security of electronic health records containing several inclusion and exclusion criteria. Researchers collected and analyzed 25 journals and reviews discussing security of electronic health records, 20 of which mentioned specific security methods and techniques. The most frequently mentioned security measures and techniques are categorized into three themes: administrative, physical, and technical safeguards. The sensitive nature of the information contained within electronic health records has prompted the need for advanced security techniques that are able to put these worries at ease. It is imperative for security techniques to cover the vast threats that are present across the three pillars of healthcare.

  20. Current trends in nuclear borehole logging techniques for elemental analysis

    International Nuclear Information System (INIS)

    1988-06-01

    This report is the result of a consultants' meeting organized by the IAEA and held in Ottawa, Canada, 2-6 November 1987 in order to assess the present technical status of nuclear borehole logging techniques, to find out the well established applications and the development trends. It contains a summary report giving a comprehensive overview of the techniques and applications and a collection of research papers describing work done in industrial institutes. A separate abstract was prepared for each of these 9 papers. Refs, figs and tabs

  1. Mound's decommissioning experience, tooling, and techniques

    International Nuclear Information System (INIS)

    Combs, A.B.; Davis, W.P.; Elswick, T.C.; Garner, J.M.; Geichman, J.R.

    1982-01-01

    Monsanto Research Corporation (MRC), which operates Mound for the Department of Energy (DOE), has been decommissioning radioactively contaminated facilities since 1949. We are currently decommissioning three plutonium-238 contaminated facilities (approximately 50,000 ft 2 ) that contained 1100 linear ft of gloveboxes; 900 linear ft of conveyor housing; 2650 linear ft of dual underground liquid waste lines; and associated contaminated piping, services, equipment, structures, and soil. As of June 1982, over 29,000 Ci of plutonium-238 have been removed in waste and scrap residues. As a result of the current and previous decommissioning projects, valuable experience has been gained in tooling and techniques. Special techniques have been developed in planning, exposure control, contamination control, equipment removal, structural decontamination, and waste packaging

  2. Neural network scatter correction technique for digital radiography

    International Nuclear Information System (INIS)

    Boone, J.M.

    1990-01-01

    This paper presents a scatter correction technique based on artificial neural networks. The technique utilizes the acquisition of a conventional digital radiographic image, coupled with the acquisition of a multiple pencil beam (micro-aperture) digital image. Image subtraction results in a sparsely sampled estimate of the scatter component in the image. The neural network is trained to develop a causal relationship between image data on the low-pass filtered open field image and the sparsely sampled scatter image, and then the trained network is used to correct the entire image (pixel by pixel) in a manner which is operationally similar to but potentially more powerful than convolution. The technique is described and is illustrated using clinical primary component images combined with scatter component images that are realistically simulated using the results from previously reported Monte Carlo investigations. The results indicate that an accurate scatter correction can be realized using this technique

  3. Optical, infrared and radio astronomy from techniques to observation

    CERN Document Server

    Poggiani, Rosa

    2017-01-01

    This textbook presents the established sciences of optical, infrared, and radio astronomy as distinct research areas, focusing on the science targets and the constraints that they place on instrumentation in the different domains. It aims to bridge the gap between specialized books and practical texts, presenting the state of the art in different techniques. For each type of astronomy, the discussion proceeds from the orders of magnitude for observable quantities that drive the building of instrumentation and the development of advanced techniques. The specific telescopes and detectors are then presented, together with the techniques used to measure fluxes and spectra. Finally, the instruments and their limits are discussed to assist readers in choice of setup, planning and execution of observations, and data reduction. The volume also includes worked examples and problem sets to improve student understanding; tables and figures in chapters summarize the state of the art of instrumentation and techniques.

  4. Tissue culture as a plant production technique for horticultural crops

    African Journals Online (AJOL)

    STORAGESEVER

    2009-08-18

    Aug 18, 2009 ... Recovery of regenerants from transformed cells. - Cell culture .... methods. Micropropagation techniques. Micropropagation is a simple concept. The basic pro- tocols were well established by the 1960s and a whole research field and ... the environment are naturally contaminated on their sur- faces (and ...

  5. Maternally Perceived Barriers to and Facilitators of Establishing and Maintaining Tooth-Brushing Routines with Infants and Preschoolers

    Directory of Open Access Journals (Sweden)

    Sarah Elison

    2014-07-01

    Full Text Available Establishing effective toothbrushing routines using fluoridated toothpaste in infancy has been suggested as important to dental health throughout childhood and into adulthood. However, previous studies have revealed a number of potential barriers to, and facilitators of caregivers ability to establish early dyadic toothbrushing routines with pre-schoolers. However, as yet no qualitative research has been conducted to ascertain potential barriers and facilitators of the earliest dyadic toothbrushing in infancy, and nor has any previous research specifically focused on how novice mothers of first-born infants and preschoolers manage this task. This study therefore outlines findings from a qualitative interview study with first-time mothers of children aged 24–30 months (n = 16 exploring perceived barriers to and facilitators of early dyadic toothbrushing routines with infants and preschoolers. A number of key themes were identified from interview transcripts and an ‘ecological’ approach conceptualised maternally perceived barriers to and facilitators of dyadic toothbrushing. Proximal influences were found to be located within the caregiver-child relationship (‘micro-system’, including parental cognitions (e.g., PSE, parental behaviours (e.g., parenting practices and infant and preschooler temperament and behaviours (e.g., tantrums. Distal factors were also identified as relevant to the establishment and maintenance of these routines, such as social support (‘exosystem’ and family history of tooth-brushing (‘chronosystem’.

  6. Reoperative sentinel lymph node biopsy after previous mastectomy.

    Science.gov (United States)

    Karam, Amer; Stempel, Michelle; Cody, Hiram S; Port, Elisa R

    2008-10-01

    Sentinel lymph node (SLN) biopsy is the standard of care for axillary staging in breast cancer, but many clinical scenarios questioning the validity of SLN biopsy remain. Here we describe our experience with reoperative-SLN (re-SLN) biopsy after previous mastectomy. Review of the SLN database from September 1996 to December 2007 yielded 20 procedures done in the setting of previous mastectomy. SLN biopsy was performed using radioisotope with or without blue dye injection superior to the mastectomy incision, in the skin flap in all patients. In 17 of 20 patients (85%), re-SLN biopsy was performed for local or regional recurrence after mastectomy. Re-SLN biopsy was successful in 13 of 20 patients (65%) after previous mastectomy. Of the 13 patients, 2 had positive re-SLN, and completion axillary dissection was performed, with 1 having additional positive nodes. In the 11 patients with negative re-SLN, 2 patients underwent completion axillary dissection demonstrating additional negative nodes. One patient with a negative re-SLN experienced chest wall recurrence combined with axillary recurrence 11 months after re-SLN biopsy. All others remained free of local or axillary recurrence. Re-SLN biopsy was unsuccessful in 7 of 20 patients (35%). In three of seven patients, axillary dissection was performed, yielding positive nodes in two of the three. The remaining four of seven patients all had previous modified radical mastectomy, so underwent no additional axillary surgery. In this small series, re-SLN was successful after previous mastectomy, and this procedure may play some role when axillary staging is warranted after mastectomy.

  7. Relationship Establishment in SCM in a Market with Enforcement and Regulation Challenges

    DEFF Research Database (Denmark)

    Nandonde, Felix Adamu; Nguni, Winnie

    2015-01-01

    of this chapter is to explore establishment of a relationship between supplier-logistic firms in a post planned economy. The study employed case study interview with two petroleum products distributors in Tanzania to achieve its objective. Data were analyzed by thematic analytical techniques. Three major findings...... regarding buyersuppliers relationships in developing economies are presented: actors do not prefer to enforce contract that they sign, discretional relationships exist in petroleum business among actors and ‘undugunization’ is the strongest criteria in selection of actors. Study implies that for a supplier-logistic...

  8. Provenance Establishment of Stingless Bee Honey Using Multi-element Analysis in Combination with Chemometrics Techniques.

    Science.gov (United States)

    Shadan, Aidil Fahmi; Mahat, Naji A; Wan Ibrahim, Wan Aini; Ariffin, Zaiton; Ismail, Dzulkiflee

    2018-01-01

    As consumption of stingless bee honey has been gaining popularity in many countries including Malaysia, ability to identify accurately its geographical origin proves pertinent for investigating fraudulent activities for consumer protection. Because a chemical signature can be location-specific, multi-element distribution patterns may prove useful for provenancing such product. Using the inductively coupled-plasma optical emission spectrometer as well as principal component analysis (PCA) and linear discriminant analysis (LDA), the distributions of multi-elements in stingless bee honey collected at four different geographical locations (North, West, East, and South) in Johor, Malaysia, were investigated. While cross-validation using PCA demonstrated 87.0% correct classification rate, the same was improved (96.2%) with the use of LDA, indicating that discrimination was possible for the different geographical regions. Therefore, utilization of multi-element analysis coupled with chemometrics techniques for assigning the provenance of stingless bee honeys for forensic applications is supported. © 2017 American Academy of Forensic Sciences.

  9. Modelling merchantable volumes for uneven aged maritime pine (Pinus pinaster Aiton stands establi-shed by natural regeneration in the central Portugal

    Directory of Open Access Journals (Sweden)

    Cristina Alegria

    2013-12-01

    Full Text Available Uneven aged maritime pine stands established by natural regeneration have a great expression in Portugal. These stands being overstocked, as opposed to those established from plantations, provide straight and cylindrical tree boles and logs with less knots that makes them very suitable for certain industrial purposes. Therefore, the aim of this study was to fit a set of equations to predict total volume and merchantable volumes to any merchantable limit for uneven aged maritime pine stands established by natural regeneration in the central inland region of Portugal. Data were collected in 30 circular sampling plots of 500 m2 of area, on 1426 trees and 314 sample trees for volume assessment, corresponding to 2353 diameter/height mea-surements. A total height equation, a total volume equation, a volume ratio equation to any top height limit and a taper equation, over bark, were fitted. To select among the best models, several statistics were computed during model fitting and the independent validation procedure to evaluate model fitting, collinearity and prediction performances. A ranking index was used to support the final decision. The models selected were then fitted again using robust regression and weighted regression techniques, because studentized residuals distribution normality and homogeneity assumptions were not observed. This research showed that the models selected for these stands were not the same as those selected in previous studies for the species in this region, suggesting that these results may be due to the influence of stand density conditions on diameter and total height growth, and consequently, on stem form and volume. This set of equations will also be included as components in a single tree growth and yield model developed for these stands. 

  10. Tracer techniques in karst hydrogeology. Application to the location of karst aquifers

    International Nuclear Information System (INIS)

    Mangin, A.; Molinari, J.

    1976-01-01

    From the recent progress in karst aquifer simulation techniques and the improved knowledge of tracers, the old-established tracer technique has become an invaluable instrument for hydrogeological survey work. Typical information obtainable includes karst system boundaries features and location of hydrodynamic discontinuities, flow variation in both space and time. Tracer methods are a basic requirement for investigation of karst groundwater supplies and determining protection zones for water supply points [fr

  11. New technique for producing the alloys based on transition metals

    International Nuclear Information System (INIS)

    Dolukhanyan, S.K.; Aleksanyan, A.G.; Shekhtman, V.Sh.; Mantashyan, A.A.; Mayilyan, D.G.; Ter-Galstyan, O.P.

    2007-01-01

    In principle new technique was elaborated for obtaining the alloys of refractory metals by their hydrides compacting and following dehydrogenation. The elaborated technique is described. The conditions of alloys formation from different hydrides of appropriate metals was investigated in detail. The influence of the process parameters such as: chemical peculiarities, composition of source hydrides, phase transformation during dehydrogenation, etc. on the alloys formation were established. The binary and tertiary alloys of α and ω phases: Ti 0 .8Zr 0 .8; Ti 0 .66Zr 0 .33; Ti 0 .3Zr 0 .8; Ti 0 .2Zr 0 .8; Ti 0 .8Hf 0 .2; Ti 0 .6Hf 0 .4Ti 0 .66Zr 0 .23Hf 0 .11; etc were recieved. Using elaborated special hydride cycle, an earlier unknown effective process for formation of alloys of transition metals was realized. The dependence of final alloy structure on the composition of initial mixture and hydrogen content in source hydrides was established

  12. Experimental determination of liquidus of Fe-Zr by spot technique

    International Nuclear Information System (INIS)

    Ramakrishna, P.; Samanta, B.; Balakrishnan, S.

    2016-01-01

    Metallic fuel alloy for fast reactor mainly consist of U-Pu-Zr housed in T91 clad. Study of thermophysical properties of fuel element and cladding material is vital for the fuel designer to optimize the design feature and predict the fuel behavior under reactor operating conditions.To understand the fuel-clad interaction the phase diagram study of Fe-Zr system is very important since future reactors use U-Pu-Zr alloy as fuel and stainless steel as clad. The eutectic temperature in Fe-Zr alloy system has been established experimentally by various methods. Information on the liquidus temperatures of Fe-Zr is scanty in the literature excepting a very few experimental measurements. Hence measurement of liquidus temperatures is very essential to establish the phase diagram. Present work concentrates more on the generation of liquidus data of Fe-Zr binary alloy system by Spot-technique. This is one among the advanced techniques for measuring the solid-liquid phase transition temperatures. (author)

  13. A Simple Technique of Supine Craniospinal Irradiation

    International Nuclear Information System (INIS)

    Munshi, Anusheel; Jalali, Rakesh

    2008-01-01

    We describe a simple procedure of craniospinal irradiation in supine position. The procedure was carried out with a 100-cm isocenter linear accelerator and compatible simulator. Treatment was with a 1 or 2 posteroanterior (PA)-directed spinal fields abutting lateral-directed cranial fields. Abutment of the fields was established by placement of markers on the neck of the patient, which provided a measure of the divergence of the spinal field. The precision and reproducibility of this technique, including the placement of junctions, appeared to be as good as for treatment in the prone position. The same could be verified with port films. We conclude that this new technique of supine craniospinal treatment is a simple and convenient alternative to traditional treatment in the prone position

  14. Learning mediastinoscopy: the need for education, experience and modern techniques--interdependency of the applied technique and surgeon's training level.

    Science.gov (United States)

    Walles, Thorsten; Friedel, Godehard; Stegherr, Tobias; Steger, Volker

    2013-04-01

    Mediastinoscopy represents the gold standard for invasive mediastinal staging. While learning and teaching the surgical technique are challenging due to the limited accessibility of the operation field, both benefited from the implementation of video-assisted techniques. However, it has not been established yet whether video-assisted mediastinoscopy improves the mediastinal staging in itself. Retrospective single-centre cohort analysis of 657 mediastinoscopies performed at a specialized tertiary care thoracic surgery unit from 1994 to 2006. The number of specimens obtained per procedure and per lymph node station (2, 4, 7, 8 for mediastinoscopy and 2-9 for open lymphadenectomy), the number of lymph node stations examined, sensitivity and negative predictive value with a focus on the technique employed (video-assisted vs standard technique) and the surgeon's experience were calculated. Overall sensitivity was 60%, accuracy was 90% and negative predictive value 88%. With the conventional technique, experience alone improved sensitivity from 49 to 57% and it was predominant at the paratracheal right region (from 62 to 82%). But with the video-assisted technique, experienced surgeons rose sensitivity from 57 to 79% in contrast to inexperienced surgeons who lowered sensitivity from 49 to 33%. We found significant differences concerning (i) the total number of specimens taken, (ii) the amount of lymph node stations examined, (iii) the number of specimens taken per lymph node station and (iv) true positive mediastinoscopies. The video-assisted technique can significantly improve the results of mediastinoscopy. A thorough education on the modern video-assisted technique is mandatory for thoracic surgeons until they can fully exhaust its potential.

  15. Establishing stereotactic body radiotherapy with flattening filter free techniques in the treatment of pulmonary lesions - initial experiences from a single institution

    International Nuclear Information System (INIS)

    Rieber, Juliane; Tonndorf-Martini, Eric; Schramm, Oliver; Rhein, Bernhard; König, Laila; Adeberg, Sebastian; Meyerhof, Eva; Mohr, Angela; Kappes, Jutta; Hoffmann, Hans; Debus, Jürgen; Rieken, Stefan

    2016-01-01

    Stereotactic body radiotherapy (SBRT) using flattening filter free (FFF)-techniques has been increasingly applied during the last years. However, clinical studies investigating this emerging technique are still rare. Hence, we analyzed toxicity and clinical outcome of pulmonary SBRT with FFF-techniques and performed dosimetric comparison to conventional techniques using flattening filters (FF). Between 05/2014 and 06/2015, 56 consecutive patients with 61 pulmonary lesions were treated with SBRT in FFF-mode. Central lesions received 8 × 7.5 Gy delivered to the conformally enclosing 80 %-isodose, while peripheral lesions were treated with 3 × 15 Gy, prescribed to the 65 %-isodose. Early and late toxicity (after 6 months) as well as initial clinical outcomes were evaluated. Furthermore, [deleted] plan quality and efficiency were evaluated by analyzing conformity, beam- on and total treatment delivery times in comparison to plans with FF-dose application. Median follow-up time was 9.3 months (range 1.5–18.0 months). Early toxicity was low with only 5 patients (8.9 %) reporting CTCAE 2° or higher side-effects. Only one patient (1.8 %) was diagnosed with radiation-induced pneumonitis CTCAE 3°, while 2 (3.6 %) patients suffered from pneumonitis CTCAE 2°. After 6 months, no toxicity greater than CTCAE 2° was reported. 1-year local progression-free survival, distant progression-free survival and overall survival were 92.8 %, 78.0 %, and 94.4 %, respectively. While plan quality was similar for FFF- and FF-plans in respect to conformity (p = 0.275), median beam-on time as well as total treatment time were significantly reduced for SBRT in FFF-mode compared to FF-mode (p ≤ 0.001, p ≤ 0.001). Patient treatment with SBRT using FFF-techniques is safe and provides promising clinical results with only modest toxicity at significantly increased dose delivery speed

  16. 77 FR 70176 - Previous Participation Certification

    Science.gov (United States)

    2012-11-23

    ... participants' previous participation in government programs and ensure that the past record is acceptable prior... information is designed to be 100 percent automated and digital submission of all data and certifications is... government programs and ensure that the past record is acceptable prior to granting approval to participate...

  17. Dose measurement techniques for high-energy photon and electron radiation

    International Nuclear Information System (INIS)

    Hohlfeld, K.; Roos, M.

    1992-08-01

    By law the Federal Institute of Physics and Technology (PTB) has been assigned the tasks of representing, preserving and passing on dose units. The analogous continuation of these tasks consists in improving, at the user level, dosimetry techniques in radiation therapy for the benefit of patients. The PTB had an essential share in working out the scientific foundations of dosimetry for high-energy radiation, and the corresponding DIN standards were established with the PTB playing a prominent part. The seminar aimed at presenting the measuring techniques fixed in the new DIN standard 6800 part 2 'Dose measurement techniques according to the probe method - ionization dosimetry', to discuss their physical background and practical implications resulting from them. (orig.) [de

  18. Techniques for Scaling Up Analyses Based on Pre-interpretations

    DEFF Research Database (Denmark)

    Gallagher, John Patrick; Henriksen, Kim Steen; Banda, Gourinath

    2005-01-01

    a variety of analyses, both generic (such as mode analysis) and program-specific (with respect to a type describing some particular property of interest). Previous work demonstrated the approach using pre-interpretations over small domains. In this paper we present techniques that allow the method...

  19. Integrating Hypermedia Techniques with Augmented Reality Environments

    OpenAIRE

    Sinclair, Patrick

    2004-01-01

    Augmented Reality systems, which overlay virtual information over the real world, can benefit greatly from the techniques established by the Open Hypermedia research field. Storing information and links separately from a document can be advantageous for augmented reality applications and can enable the adaption of content to suit users’ preferences. This thesis explores how Open Hypermedia systems might be used as the information systems behind AR environments. This provides benefits to augme...

  20. Generic Techniques for the Calibration of Robots with Application of the 3-D Fixtures and Statistical Technique on the PUMA 500 and ARID Robots

    Science.gov (United States)

    Tawfik, Hazem

    1991-01-01

    A relatively simple, inexpensive, and generic technique that could be used in both laboratories and some operation site environments is introduced at the Robotics Applications and Development Laboratory (RADL) at Kennedy Space Center (KSC). In addition, this report gives a detailed explanation of the set up procedure, data collection, and analysis using this new technique that was developed at the State University of New York at Farmingdale. The technique was used to evaluate the repeatability, accuracy, and overshoot of the Unimate Industrial Robot, PUMA 500. The data were statistically analyzed to provide an insight into the performance of the systems and components of the robot. Also, the same technique was used to check the forward kinematics against the inverse kinematics of RADL's PUMA robot. Recommendations were made for RADL to use this technique for laboratory calibration of the currently existing robots such as the ASEA, high speed controller, Automated Radiator Inspection Device (ARID) etc. Also, recommendations were made to develop and establish other calibration techniques that will be more suitable for site calibration environment and robot certification.

  1. Application of metabonomic analytical techniques in the modernization and toxicology research of traditional Chinese medicine.

    Science.gov (United States)

    Lao, Yong-Min; Jiang, Jian-Guo; Yan, Lu

    2009-08-01

    In the recent years, a wide range of metabonomic analytical techniques are widely used in the modern research of traditional Chinese medicine (TCM). At the same time, the international community has attached increasing importance to TCM toxicity problems. Thus, many studies have been implemented to investigate the toxicity mechanisms of TCM. Among these studies, many metabonomic-based methods have been implemented to facilitate TCM toxicity investigation. At present, the most prevailing methods for TCM toxicity research are mainly single analysis techniques using only one analytical means. These techniques include nuclear magnetic resonance (NMR), gas chromatography-mass spectrometry (GC-MS), and liquid chromatography-mass spectrometry (LC-MS), etc.; with these techniques, some favourable outcomes have been gained in the toxic reaction studies of TCM, such as the action target organs assay, the establishment of action pattern, the elucidation of action mechanism and the exploration of action material foundation. However, every analytical technique has its advantages and drawbacks, no existing analytical technique can be versatile. Multi-analysed techniques can partially overcome the shortcomings of single-analysed techniques. Combination of GC-MS and LC-MS metabolic profiling approaches has unravelled the pathological outcomes of aristolochic acid-induced nephrotoxicity, which can not be achieved by single-analysed techniques. It is believed that with the further development of metabonomic analytical techniques, especially multi-analysed techniques, metabonomics will greatly promote TCM toxicity research and be beneficial to the modernization of TCM in terms of extending the application of modern means in the TCM safety assessment, assisting the formulation of TCM safety norms and establishing the international standards indicators.

  2. Utilization of Cell-Transfer Technique for Molecular Testing on Hematoxylin-Eosin-Stained Sections: A Viable Option for Small Biopsies That Lack Tumor Tissues in Paraffin Block.

    Science.gov (United States)

    Wu, Howard H; Jovonovich, Stephen M; Randolph, Melissa; Post, Kristin M; Sen, Joyashree D; Curless, Kendra; Cheng, Liang

    2016-12-01

    - In some instances the standard method of doing molecular testing from formalin-fixed, paraffin-embedded block is not possible because of limited tissue. Tumor cell-enriched cell-transfer technique has been proven useful for performing immunocytochemistry and molecular testing on cytologic smears. - To establish the cell-transfer technique as a viable option for isolating tumor cells from hematoxylin-eosin (H&E)-stained slides. - Molecular testing was performed by using the cell-transfer technique on 97 archived H&E-stained slides from a variety of different tumors. Results were compared to the conventional method of molecular testing. - Polymerase chain reaction-based molecular testing via the cell-transfer technique was successfully performed on 82 of 97 samples (85%). This included 39 of 47 cases for EGFR, 10 of 11 cases for BRAF, and 33 of 39 cases for KRAS mutations. Eighty-one of 82 cell-transfer technique samples (99%) showed agreement with previous standard method results, including 4 mutations and 35 wild-type alleles for EGFR, 4 mutations and 6 wild-type alleles for BRAF, and 11 mutations and 21 wild-type alleles for KRAS. There was only 1 discrepancy: a cell-transfer technique with a false-negative >KRAS result (wild type versus G12C). - Molecular testing performed on H&E-stained sections via cell-transfer technique is useful when tissue from cell blocks and small surgical biopsy samples is exhausted and the only available material for testing is on H&E-stained slides.

  3. Metallographic techniques for evaluation of thermal barrier coatings

    Science.gov (United States)

    Brindley, William J.; Leonhardt, Todd A.

    1990-01-01

    The performance of ceramic thermal barrier coatings is strongly dependent on the amount and shape of the porosity in the coating. Current metallographic techniques do not provide polished surfaces that are adequate for a repeatable interpretation of the coating structures. A technique recently developed at NASA-Lewis for preparation of thermal barrier coating sections combines epoxy impregnation, careful sectioning and polishing, and interference layering to provide previously unobtainable information on processing-induced porosity. In fact, increased contrast and less ambiguous structure developed by the method make automatic quantitative metallography a viable option for characterizing thermal barrier coating structures.

  4. Drug Establishments Current Registration Site

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Drug Establishments Current Registration Site (DECRS) is a database of current information submitted by drug firms to register establishments (facilities) which...

  5. Effectiveness of relaxation techniques before diagnostic screening of cancer patients

    Directory of Open Access Journals (Sweden)

    Montserrat Aiger

    2016-07-01

    Full Text Available Psychophysiological arousal was observed in cancer patients during the application of relaxation techniques prior to a diagnostic scan (PET-CT. The aim of the study is twofold: firstly, it is sought to establish whether such techniques can minimize patient arousal before diagnostic screening begins, and secondly to measure which of them are most effective. The dependent variable is electrodermal activity, recording the attentional level and emotional response, and the independent variable comprises the relaxation techniques used, namely Jacobson, breathing and visualization. The 39 patients were split into experimental groups to whom the relaxation techniques (Jacobson, breathing exercises, and visualization were applied before they went for the PET-CT. An activity-module procedure was applied to track electrodermal activity during the relaxation sessions, consisting of instructions, timeout; wait, task; relaxation and end of the recording session. The control group received no relaxation techniques before the PET-CT. Session-end results show that patients who perform relaxation techniques achieve greater attentional focus using Jacobson's technique (M = .212 and enhanced emotional containment using visualization (M = .206. It is concluded that relaxation techniques minimize the state of activation during the waiting period before a diagnostic scan.

  6. Effects of previous intrusion pressure on territorial responses in nightingales

    NARCIS (Netherlands)

    Sprau, P.; Roth, T.; Amrhrein, V.; Naguib, M.

    2014-01-01

    In territorial animals, establishing and defending a territory against rivals is commonly a prerequisite for successful reproduction. Yet, often, non-territorial males that are seeking to establish their own territory may intrude into occupied territories and persistently challenge residents in

  7. The establishment of histology in the curriculum of the London medical schools:1826-1886.

    OpenAIRE

    Bracegirdle, P. H.

    1996-01-01

    This thesis sets out the way in which histology became established in the curriculum of the London medical schools between 1826 and 1886. The text provides a very large number of references to original material, some of it previously unreported. Histology had its origins in continental Europe in the early years of the nineteenth century, in the work of Bichat. The introductory chapter examines how this was translated both as to language and as to practical experience into En...

  8. Establishment of a clonal bank of Caesalpinia spinosa (Mol.) O. Kuntz by selection of plus trees and grafting

    OpenAIRE

    Jenny E Nuñez; Elisa Quiala; Manuel de Feria; Saúl Mestanza; Rafael Gómez-Kosky; Franklin R Cuadrado; Michel Leiva-Mora

    2017-01-01

    In Ecuador, plant propagation techniques are not available commercially to establish clonal banks of Caesalpinia spinosa (Mol.) O. Kuntz (guarango) plus trees, which limits the development of in vitro propagation protocols of this specie. The objective of the present work was to establish a clonal bank of C. spinosa by selecting plus trees and grafting. Guarango trees belonging to the province of Chimborazo, Guano canton were selected based on total height, height at the beginning of the crow...

  9. Contemporary behavior management techniques in clinical pediatric dentistry: out with the old and in with the new?

    Science.gov (United States)

    Oliver, Kelly; Manton, David John

    2015-01-01

    Effective behavior management guides children through the complex social context of dentistry utilizing techniques based on a current understanding of the social, emotional, and cognitive development of children. Behavior management techniques facilitate effective communication and establish social and behavioral guidelines for the dental environment. Contemporary parenting styles, expectations, and attitudes of modern parents and society have influenced the use of behavior management techniques with a prevailing emphasis on communicative techniques and pharmacological management over aversive techniques.

  10. [Prevalence of previously diagnosed diabetes mellitus in Mexico.

    Science.gov (United States)

    Rojas-Martínez, Rosalba; Basto-Abreu, Ana; Aguilar-Salinas, Carlos A; Zárate-Rojas, Emiliano; Villalpando, Salvador; Barrientos-Gutiérrez, Tonatiuh

    2018-01-01

    To compare the prevalence of previously diagnosed diabetes in 2016 with previous national surveys and to describe treatment and its complications. Mexico's national surveys Ensa 2000, Ensanut 2006, 2012 and 2016 were used. For 2016, logistic regression models and measures of central tendency and dispersion were obtained. The prevalence of previously diagnosed diabetes in 2016 was 9.4%. The increase of 2.2% relative to 2012 was not significant and only observed in patients older than 60 years. While preventive measures have increased, the access to medical treatment and lifestyle has not changed. The treatment has been modified, with an increase in insulin and decrease in hypoglycaemic agents. Population aging, lack of screening actions and the increase in diabetes complications will lead to an increase on the burden of disease. Policy measures targeting primary and secondary prevention of diabetes are crucial.

  11. An analog simulation technique for distributed flow systems

    DEFF Research Database (Denmark)

    Jørgensen, Sten Bay; Kümmel, Mogens

    1973-01-01

    earlier[3]. This is an important extension since flow systems are frequently controlled through manipulation of the flow rate. Previously the tech­nique has been applied with constant flows [4, 5]. Results demonstrating the new hardware are presented from simula­tion of a transportation lag and a double......Simulation of distributed flow systems in chemical engine­ering has been applied more and more during the last decade as computer techniques have developed [l]. The applications have served the purpose of identification of process dynamics and parameter estimation as well as improving process...... and process control design. Although the conventional analog computer has been expanded with hybrid techniques and digital simulation languages have appeared, none of these has demonstrated superiority in simulating distributed flow systems in general [l]. Conventional analog techniques are expensive...

  12. Experimental Technique of Titanium Fire in Aero-engine

    Directory of Open Access Journals (Sweden)

    MI Guangbao

    2016-06-01

    Full Text Available Titanium fire is the typical catastrophic fault in the aero-engine. Aiming at the urgent demand for experimental technique of titanium fire from advanced high thrust-weight ratio aero-engine, the combustion technology and theory of titanium alloy based on friction oxygen concentration method (FOC were systematically studied. The evaluation method of fireproof property and the friction ignition model were built, and the fireproof mechanism was illustrated. By generalizing recent progress in experimental technique of titanium fire from three levels, including evolutionary rule, mechanism and prevention and control technology, the ideas and directions of experimental technique associated with the application research of titanium fire in the future were proposed, namely overall evaluation of fireproof property close to air flow environment of the aero-engine, prediction model of fireproof property and experimental verification of fireproof technique under the air flow environment of aero-engine. It is necessary to establish the prevention system of titanium fire in aero-engine, which contributes to the realization of "full titanium" in compressor and to the increase of high thrust-weight ratio.

  13. Digital mapping techniques '06 - Workshop proceedings

    Science.gov (United States)

    Soller, David R.

    2007-01-01

    The Digital Mapping Techniques `06 (DMT`06) workshop was attended by more than 110 technical experts from 51 agencies, universities, and private companies, including representatives from 27 state geological surveys (see Appendix A of these Proceedings). This workshop was similar in nature to the previous nine meetings, which were held in Lawrence, Kansas (Soller, 1997), Champaign, Illinois (Soller, 1998), Madison, Wisconsin (Soller, 1999), Lexington, Kentucky (Soller, 2000), Tuscaloosa, Alabama (Soller, 2001), Salt Lake City, Utah (Soller, 2002), Millersville, Pennsylvania (Soller, 2003), Portland, Oregon (Soller, 2004), and Baton Rouge, Louisiana (Soller, 2005). This year?s meeting was hosted by the Ohio Geological Survey, from June 11-14, 2006, on the Ohio State University campus in Columbus, Ohio. As in the previous meetings, the objective was to foster informal discussion and exchange of technical information. It is with great pleasure that I note that the objective was successfully met, as attendees continued to share and exchange knowledge and information, and renew friendships and collegial work begun at past DMT workshops.Each DMT workshop has been coordinated by the Association of American State Geologists (AASG) and U.S. Geological Survey (USGS) Data Capture Working Group, the latter of which was formed in August 1996 to support the AASG and the USGS in their effort to build a National Geologic Map Database (see Soller, this volume, and http://ngmdb.usgs.gov/info/standards/datacapt/). The Working Group was formed because increased production efficiencies, standardization, and quality of digital map products were needed for the database - and for the State and Federal geological surveys - to provide more high-quality digital maps to the public.At the 2006 meeting, oral and poster presentations and special discussion sessions emphasized: 1) methods for creating and publishing map products (here, "publishing" includes Web-based release); 2) field data

  14. Review of nipple reconstruction techniques and introduction of v to y technique in a bilateral wise pattern mastectomy or reduction mammaplasty.

    Science.gov (United States)

    Riccio, Charles A; Zeiderman, Matthew R; Chowdhry, Saeed; Wilhelmi, Bradon J

    2015-01-01

    Nipple-areola complex reconstruction (NAR) is the final procedure in breast reconstruction after the majority of mastectomies. Many methods of NAR have been described, each with inherent advantages and disadvantages depending on local healthy tissue availability, previous scarring and procedures, and the operative morbidity of the NAR technique. Nipple reconstructions may be complicated by scars or previous nipple reconstruction, making the procedure more challenging. We propose the use of the V-Y advancement flap as a new method that is suitable for both novice and experienced surgeons wishing to broaden their range of techniques for difficult nipple reconstructions. A traditional V-Y advancement flap is lifted at the site of the future nipple. Mastectomy scars from prior mastectomy, mammoplasty, or nipple reconstruction can be incorporated into the flap. The flap is folded caudally upon itself and the secondary defect at the apex of the flap is linearly closed. At 6-month postoperative evaluation, adequate nipple projection and patient satisfaction were achieved with this method. The V-Y advancement flap is a suitable method for achieving satisfactory results when faced with challenging NAR. The method is easy to perform, reproducible, has low operative morbidity, and incorporates previous wise pattern mastectomy or mammaplasty scars into the newly reconstructed nipple, thereby decreasing new scar formation on the breast and leading to favorable cosmetic results.

  15. Experimental techniques for single cell and single molecule biomechanics

    International Nuclear Information System (INIS)

    Lim, C.T.; Zhou, E.H.; Li, A.; Vedula, S.R.K.; Fu, H.X.

    2006-01-01

    Stresses and strains that act on the human body can arise either from external physical forces or internal physiological environmental conditions. These biophysical interactions can occur not only at the musculoskeletal but also cellular and molecular levels and can determine the health and function of the human body. Here, we seek to investigate the structure-property-function relationship of cells and biomolecules so as to understand their important physiological functions as well as establish possible connections to human diseases. With the recent advancements in cell and molecular biology, biophysics and nanotechnology, several innovative and state-of-the-art experimental techniques and equipment have been developed to probe the structural and mechanical properties of biostructures from the micro- down to picoscale. Some of these experimental techniques include the optical or laser trap method, micropipette aspiration, step-pressure technique, atomic force microscopy and molecular force spectroscopy. In this article, we will review the basic principles and usage of these techniques to conduct single cell and single molecule biomechanics research

  16. Selecting a Sustainable Disinfection Technique for Wastewater Reuse Projects

    Directory of Open Access Journals (Sweden)

    Jorge Curiel-Esparza

    2014-09-01

    Full Text Available This paper presents an application of the Analytical Hierarchy Process (AHP by integrating a Delphi process for selecting the best sustainable disinfection technique for wastewater reuse projects. The proposed methodology provides project managers a tool to evaluate problems with multiple criteria and multiple alternatives which involve non-commeasurable decision criteria, with expert opinions playing a major role in the selection of these treatment technologies. Five disinfection techniques for wastewater reuse have been evaluated for each of the nine criteria weighted according to the opinions of consulted experts. Finally, the VIKOR method has been applied to determine a compromise solution, and to establish the stability of the results. Therefore, the expert system proposed to select the optimal disinfection alternative is a hybrid method combining the AHP with the Delphi method and the VIKOR technique, which is shown to be appropriate in realistic scenarios where multiple stakeholders are involved in the selection of a sustainable disinfection technique for wastewater reuse projects.

  17. Development of automatic techniques for GPS data management

    International Nuclear Information System (INIS)

    Park, Pil Ho

    2001-06-01

    It is necessary for GPS center to establish automatization as effective management of GPS network including data gathering, data transformation, data backup, data sending to IGS (International GPS Service for geodynamics), and precise ephemerides gathering. The operating program of GPS center has been adopted at KCSC (Korea Cadastral Survey Corporation), NGI (National Geography Institute), MOMAF (Ministry of Maritime Affairs and Fisheries) without self-development of core technique. The automatic management of GPS network is consists of GPS data management and data processing. It is also fundamental technique, which should be accomplished by every GPS centers. Therefore, this study carried out analyzing of Japanese GPS center, which has accomplished automatization by module considering applicability for domestic GPS centers

  18. Technique to match mantle and para-aortic fields

    International Nuclear Information System (INIS)

    Lutz, W.R.; Larsen, R.D.

    1983-01-01

    A technique is described to match the mantle and para-aortic fields used in treatment of Hodgkin's disease, when the patient is treated alternately in supine and prone position. The approach is based on referencing the field edges to a point close to the vertebral column, where uncontrolled motion is minimal and where accurate matching is particularly important. Fiducial surface points are established in the simulation process to accomplish the objective. Dose distributions have been measured to study the combined effect of divergence differences, changes in body angulation and setup errors. Even with the most careful technique, the use of small cord blocks of 50% transmission is an advisable precaution for the posterior fields

  19. Hyphenated analytical techniques for materials characterisation

    International Nuclear Information System (INIS)

    Armstrong, Gordon; Kailas, Lekshmi

    2017-01-01

    This topical review will provide a survey of the current state of the art in ‘hyphenated’ techniques for characterisation of bulk materials, surface, and interfaces, whereby two or more analytical methods investigating different properties are applied simultaneously to the same sample to better characterise the sample than can be achieved by conducting separate analyses in series using different instruments. It is intended for final year undergraduates and recent graduates, who may have some background knowledge of standard analytical techniques, but are not familiar with ‘hyphenated’ techniques or hybrid instrumentation. The review will begin by defining ‘complementary’, ‘hybrid’ and ‘hyphenated’ techniques, as there is not a broad consensus among analytical scientists as to what each term means. The motivating factors driving increased development of hyphenated analytical methods will also be discussed. This introduction will conclude with a brief discussion of gas chromatography-mass spectroscopy and energy dispersive x-ray analysis in electron microscopy as two examples, in the context that combining complementary techniques for chemical analysis were among the earliest examples of hyphenated characterisation methods. The emphasis of the main review will be on techniques which are sufficiently well-established that the instrumentation is commercially available, to examine physical properties including physical, mechanical, electrical and thermal, in addition to variations in composition, rather than methods solely to identify and quantify chemical species. Therefore, the proposed topical review will address three broad categories of techniques that the reader may expect to encounter in a well-equipped materials characterisation laboratory: microscopy based techniques, scanning probe-based techniques, and thermal analysis based techniques. Examples drawn from recent literature, and a concluding case study, will be used to explain the

  20. Hyphenated analytical techniques for materials characterisation

    Science.gov (United States)

    Armstrong, Gordon; Kailas, Lekshmi

    2017-09-01

    This topical review will provide a survey of the current state of the art in ‘hyphenated’ techniques for characterisation of bulk materials, surface, and interfaces, whereby two or more analytical methods investigating different properties are applied simultaneously to the same sample to better characterise the sample than can be achieved by conducting separate analyses in series using different instruments. It is intended for final year undergraduates and recent graduates, who may have some background knowledge of standard analytical techniques, but are not familiar with ‘hyphenated’ techniques or hybrid instrumentation. The review will begin by defining ‘complementary’, ‘hybrid’ and ‘hyphenated’ techniques, as there is not a broad consensus among analytical scientists as to what each term means. The motivating factors driving increased development of hyphenated analytical methods will also be discussed. This introduction will conclude with a brief discussion of gas chromatography-mass spectroscopy and energy dispersive x-ray analysis in electron microscopy as two examples, in the context that combining complementary techniques for chemical analysis were among the earliest examples of hyphenated characterisation methods. The emphasis of the main review will be on techniques which are sufficiently well-established that the instrumentation is commercially available, to examine physical properties including physical, mechanical, electrical and thermal, in addition to variations in composition, rather than methods solely to identify and quantify chemical species. Therefore, the proposed topical review will address three broad categories of techniques that the reader may expect to encounter in a well-equipped materials characterisation laboratory: microscopy based techniques, scanning probe-based techniques, and thermal analysis based techniques. Examples drawn from recent literature, and a concluding case study, will be used to explain the

  1. The establishment and spread of myxomatosis and its effect on rabbit populations.

    Science.gov (United States)

    Ross, J; Tittensor, A M

    1986-12-15

    The establishment of myxomatosis, the spread of the disease and its effects on rabbit populations in Australia and in Britain are briefly reviewed. Though the disease is endemic, with regular outbreaks in most rabbit populations, its effect is now much less dramatic than previously. Recent epidemiological studies have shown that the rate of spread of infection, the proportion of rabbits infected and the proportion dying from the disease are very much smaller than recorded in earlier outbreaks. The reasons for these changes are discussed, and the epidemiology of the disease in Britain is compared with that in Australia.

  2. An improved technique for fission track dating

    International Nuclear Information System (INIS)

    Zhao Yunlong; Wu Zhaohui; Xia Yuliang

    1996-01-01

    The necessity of improving the fission track dating (FTD) technique both at home and abroad is illustrated. The ways of making such improvement are also proposed. It is suggested to calibrate the constant b value of the uranium standard glass by using the method of fission products activity. The 3 kinds of uranium standard glass which have been calibrated are NBS SRM962a, UB 1 and UB 2 . An established new method σ·Φ ρ d /b, to measure neutron fluence, avoids the influence of the varying neutron spectrum on measuring neutron fluence. The improved etching technique for fission tracks in zircon adopted a two-step method which includes the molten alkali system etching using NaOH + KOH and the mixed acid system etching using HNO 3 + HF; this technique results in adequate track etching, increased track clarity and less interference. In this way the intensity of tracks is authentically reflected. Dividing angular zone in accordance with the angular distribution of spontaneous fission track on the crystal surface of minerals to count the tracks and using the improved etching technique to remove the non-uniform angular distribution of spontaneous fission tracks in zircon, ensure the accuracy of tracks count. The improved FTD techniques were used to finish Laboratory Standardized Calibration. The tests using international FTD age standards samples have proved that above mentioned techniques are reliable and practical in obtaining the accurate FTD data. (8 tabs.; 3 figs.)

  3. Public Relations and Publicity: Tools and Techniques for Student Organizations.

    Science.gov (United States)

    DeFeo, Carol Jean

    Based on the idea that to be successful, a student organization must have a sound public relations and publicity program, this handbook considers techniques of internal communication that establish good public relations with various special groups: the student body, the administration, the faculty, and the staff. The handbook states that…

  4. Scaling Analysis Techniques to Establish Experimental Infrastructure for Component, Subsystem, and Integrated System Testing

    Energy Technology Data Exchange (ETDEWEB)

    Sabharwall, Piyush [Idaho National Laboratory (INL), Idaho Falls, ID (United States); O' Brien, James E. [Idaho National Laboratory (INL), Idaho Falls, ID (United States); McKellar, Michael G. [Idaho National Laboratory (INL), Idaho Falls, ID (United States); Housley, Gregory K. [Idaho National Laboratory (INL), Idaho Falls, ID (United States); Bragg-Sitton, Shannon M. [Idaho National Laboratory (INL), Idaho Falls, ID (United States)

    2015-03-01

    Hybrid energy system research has the potential to expand the application for nuclear reactor technology beyond electricity. The purpose of this research is to reduce both technical and economic risks associated with energy systems of the future. Nuclear hybrid energy systems (NHES) mitigate the variability of renewable energy sources, provide opportunities to produce revenue from different product streams, and avoid capital inefficiencies by matching electrical output to demand by using excess generation capacity for other purposes when it is available. An essential step in the commercialization and deployment of this advanced technology is scaled testing to demonstrate integrated dynamic performance of advanced systems and components when risks cannot be mitigated adequately by analysis or simulation. Further testing in a prototypical environment is needed for validation and higher confidence. This research supports the development of advanced nuclear reactor technology and NHES, and their adaptation to commercial industrial applications that will potentially advance U.S. energy security, economy, and reliability and further reduce carbon emissions. Experimental infrastructure development for testing and feasibility studies of coupled systems can similarly support other projects having similar developmental needs and can generate data required for validation of models in thermal energy storage and transport, energy, and conversion process development. Experiments performed in the Systems Integration Laboratory will acquire performance data, identify scalability issues, and quantify technology gaps and needs for various hybrid or other energy systems. This report discusses detailed scaling (component and integrated system) and heat transfer figures of merit that will establish the experimental infrastructure for component, subsystem, and integrated system testing to advance the technology readiness of components and systems to the level required for commercial

  5. Moisture availability limits subalpine tree establishment.

    Science.gov (United States)

    Andrus, Robert A; Harvey, Brian J; Rodman, Kyle C; Hart, Sarah J; Veblen, Thomas T

    2018-03-01

    In the absence of broad-scale disturbance, many temperate coniferous forests experience successful seedling establishment only when abundant seed production coincides with favorable climate. Identifying the frequency of past establishment events and the climate conditions favorable for seedling establishment is essential to understanding how climate warming could affect the frequency of future tree establishment events and therefore future forest composition or even persistence of a forest cover. In the southern Rocky Mountains, USA, research on the sensitivity of establishment of Engelmann spruce (Picea engelmannii) and subalpine fir (Abies lasiocarpa)-two widely distributed, co-occurring conifers in North America-to climate variability has focused on the alpine treeline ecotone, leaving uncertainty about the sensitivity of these species across much of their elevation distribution. We compared annual germination dates for >450 Engelmann spruce and >500 subalpine fir seedlings collected across a complex topographic-moisture gradient to climate variability in the Colorado Front Range. We found that Engelmann spruce and subalpine fir established episodically with strong synchrony in establishment events across the study area. Broad-scale establishment events occurred in years of high soil moisture availability, which were characterized by above-average snowpack and/or cool and wet summer climatic conditions. In the recent half of the study period (1975-2010), a decrease in the number of fir and spruce establishment events across their distribution coincided with declining snowpack and a multi-decadal trend of rising summer temperature and increasing moisture deficits. Counter to expected and observed increases in tree establishment with climate warming in maritime subalpine forests, our results show that recruitment declines will likely occur across the core of moisture-limited subalpine tree ranges as warming drives increased moisture deficits. © 2018 by the

  6. Preconditioned conjugate gradient technique for the analysis of symmetric anisotropic structures

    Science.gov (United States)

    Noor, Ahmed K.; Peters, Jeanne M.

    1987-01-01

    An efficient preconditioned conjugate gradient (PCG) technique and a computational procedure are presented for the analysis of symmetric anisotropic structures. The technique is based on selecting the preconditioning matrix as the orthotropic part of the global stiffness matrix of the structure, with all the nonorthotropic terms set equal to zero. This particular choice of the preconditioning matrix results in reducing the size of the analysis model of the anisotropic structure to that of the corresponding orthotropic structure. The similarities between the proposed PCG technique and a reduction technique previously presented by the authors are identified and exploited to generate from the PCG technique direct measures for the sensitivity of the different response quantities to the nonorthotropic (anisotropic) material coefficients of the structure. The effectiveness of the PCG technique is demonstrated by means of a numerical example of an anisotropic cylindrical panel.

  7. Doxorubicin and ifosfamide combination chemotherapy in previously treated acute leukemia in adults: a Southwest Oncology Group pilot study.

    Science.gov (United States)

    Ryan, D H; Bickers, J N; Vial, R H; Hussein, K; Bottomley, R; Hewlett, J S; Wilson, H E; Stuckey, W J

    1980-01-01

    The Southwest Oncology Group did a limited institutional pilot study of the combination of doxorubicin and ifosfamide in the treatment of previously treated adult patients with acute leukemia. Thirty-four patients received one or two courses of the combination. All patients had received prior chemotherapy and 32 had received prior anthracycline chemotherapy. Three patients died before their responses could be fully evaluated. Fourteen patients achieved complete remission (41%) and one patient achieved partial remission. The complete remission rate was 27% for patients with acute myeloblastic leukemia (myelomonoblastic leukemia, monoblastic leukemia, and erythroleukemia) and 89% for patients with acute lymphocytic and undifferentiated leukemia (ALL). Toxic effects included severe hematologic reactions in 33 of 34 patients, hematuria in six patients, altered sensorium in one patient, and congestive heart failure in one patient. The safety of the combination was established and toxic side effects of this therapy were tolerable. The 89% complete remission rate for previously treated patients with ALL suggests that the combination of doxorubicin and ifosfamide may be particularly effective in ALL.

  8. Industrial technique

    International Nuclear Information System (INIS)

    Robertson, D.H.

    1975-01-01

    Techniques for selectively extracting and storing only krypton and xenon in the waste gases that are released from a pressurized water nuclear power reactor are described. The illustrative fluorocarbon absorption system has three separation stages: an initial gas-fluorocarbon absorber, a flash chamber and fractionator for segregating all of the absorbed gases from the loaded absorber stage fluorocarbon (save for the krypton and xenon), and a stripper that receives the partially loaded fluorocarbon liquid directly from the fractionator in order to separate only the krypton and xenon. A molecular sieve filter dries the input process gas, a cartridge type solvent filter is used to remove radiation degradation products from the loaded liquid that flows from the absorber, a cold trap gas drier is provided to remove residual solvent vapor from the separated krypton and xenon, and radiation detectors automatically activate valves to establish safe conditions in the event of an accident or plant failure. (U.S.)

  9. Precise determination of Pb isotope ratios by simple double spike MC-ICP-MS technique without Tl addition

    Digital Repository Service at National Institute of Oceanography (India)

    Makishima, A.; Nath, B.N.; Nakamura, E.

    A double-spike multicollector ICP-MS (DS-MC-ICP-MS) technique for Pb isotope analysis without Tl addition is established and its analytical performance is examined in detail. This simple DS-MC-ICP-MS technique using 20 ng ml sup(-1) gave averages...

  10. [Establishment of a novel HLA genotyping method for preimplantation genetic diagnonis using multiple displacement amplification-polymerase chain reaction-sequencing based technique].

    Science.gov (United States)

    Zhang, Yinfeng; Luo, Haining; Zhang, Yunshan

    2015-12-01

    To establish a novel HLA genotyping method for preimplantation genetic diagnonis (PGD) using multiple displacement amplification-polymerase chain reaction-sequencing based technique (MDA-PCR-SBT). Peripheral blood samples and 76 1PN, 2PN, 3PN discarded embryos from 9 couples were collected. The alleles of HLA-A, B, DR loci were detected from the MDA product with the PCR-SBT method. The HLA genotypes of the parental peripheral blood samples were analyzed with the same protocol. The genotypes of specific HLA region were evaluated for distinguishing the segregation of haplotypes among the family members, and primary HLA matching was performed between the embryos. The 76 embryos were subjected to MDA and 74 (97.4%) were successfully amplified. For the 34 embryos from the single blastomere group, the amplification rate was 94.1%, and for the 40 embryos in the two blastomeres group, the rate was 100%. The dropout rates for DQ allele and DR allele were 1.3% and 0, respectively. The positive rate for MDA in the single blastomere group was 100%, with the dropout rates for DQ allele and DR allele being 1.5% and 0, respectively. The positive rate of MDA for the two blastomere group was 100%, with the dropout rates for both DQ and DR alleles being 0. The recombination rate of fetal HLA was 20.2% (30/148). Due to the improper classification and abnormal fertilized embryos, the proportion of matched embryos HLA was 20.3% (15/74),which was lower than the theoretical value of 25%. PGD with HLA matching can facilitate creation of a HLA-identical donor (saviour child) for umbilical cord blood or bone marrow stem cells for its affected sibling with a genetic disease. Therefore, preimplantation HLA matching may provide a tool for couples desiring to conceive a potential donor progeny for transplantation for its sibling with a life-threatening disorder.

  11. Two techniques for mapping and area estimation of small grains in California using Landsat digital data

    Science.gov (United States)

    Sheffner, E. J.; Hlavka, C. A.; Bauer, E. M.

    1984-01-01

    Two techniques have been developed for the mapping and area estimation of small grains in California from Landsat digital data. The two techniques are Band Ratio Thresholding, a semi-automated version of a manual procedure, and LCLS, a layered classification technique which can be fully automated and is based on established clustering and classification technology. Preliminary evaluation results indicate that the two techniques have potential for providing map products which can be incorporated into existing inventory procedures and automated alternatives to traditional inventory techniques and those which currently employ Landsat imagery.

  12. Performance Monitoring Techniques Supporting Cognitive Optical Networking

    DEFF Research Database (Denmark)

    Caballero Jambrina, Antonio; Borkowski, Robert; Zibar, Darko

    2013-01-01

    High degree of heterogeneity of future optical networks, such as services with different quality-of-transmission requirements, modulation formats and switching techniques, will pose a challenge for the control and optimization of different parameters. Incorporation of cognitive techniques can help...... to solve this issue by realizing a network that can observe, act, learn and optimize its performance, taking into account end-to-end goals. In this letter we present the approach of cognition applied to heterogeneous optical networks developed in the framework of the EU project CHRON: Cognitive...... Heterogeneous Reconfigurable Optical Network. We focus on the approaches developed in the project for optical performance monitoring, which enable the feedback from the physical layer to the cognitive decision system by providing accurate description of the performance of the established lightpaths....

  13. Digital Mapping Techniques '10-Workshop Proceedings, Sacramento, California, May 16-19, 2010

    Science.gov (United States)

    Soller, David R.; Soller, David R.

    2012-01-01

    The Digital Mapping Techniques '10 (DMT'10) workshop was attended by 110 technical experts from 40 agencies, universities, and private companies, including representatives from 19 State geological surveys (see Appendix A). This workshop, hosted by the California Geological Survey, May 16-19, 2010, in Sacramento, California, was similar in nature to the previous 13 meetings (see Appendix B). The meeting was coordinated by the U.S. Geological Survey's (USGS) National Geologic Map Database project. As in the previous meetings, the objective was to foster informal discussion and exchange of technical information. It is with great pleasure that I note that the objective was again successfully met, as attendees continued to share and exchange knowledge and information, and renew friendships and collegial work begun at past DMT workshops. At this meeting, oral and poster presentations and special discussion sessions emphasized (1) methods for creating and publishing map products ("publishing" includes Web-based release); (2) field data capture software and techniques, including the use of LiDAR; (3) digital cartographic techniques; (4) migration of digital maps into ArcGIS Geodatabase format; (5) analytical GIS techniques; and (6) continued development of the National Geologic Map Database.

  14. In vitro techniques for crop improvement

    International Nuclear Information System (INIS)

    1985-01-01

    The film refers to principles of plant tissue culture - laboratory requirements, media preparation, explant establishment and subculturing method. In vitro growth and development of crop plants are demonstrate and the application of in vitro techniques in plant breeding is discussed. The second part of the film shows the application of cell, tissue and organ culture in plants. Micropropagation and virus eradication are important technologies for the improvement of vegetatively propagated plants; zygotic embryo rescue techniques are used for distant hybridization, especially in cereals. Plant biotechnology offers a potent means for the in vitro generation of enhanced genetic variability - somaclonal and mutagen induced variation. Principles of the isolation and culture of plant protoplasts are explained and their potential for somatic hybridization in higher plants is demonstrated. Haploids are valuable to accelerate breeding cycles of plants. Plant biotechnology is described as an important complementary tool to conventional plant breeding methods

  15. Solar Cell Calibration and Measurement Techniques

    Science.gov (United States)

    Bailey, Sheila; Brinker, Dave; Curtis, Henry; Jenkins, Phillip; Scheiman, Dave

    2004-01-01

    The increasing complexity of space solar cells and the increasing international markets for both cells and arrays has resulted in workshops jointly sponsored by NASDA, ESA and NASA. These workshops are designed to obtain international agreement on standardized values for the AMO spectrum and constant, recommend laboratory measurement practices and establish a set of protocols for international comparison of laboratory measurements. A working draft of an ISO standard, WD15387, "Requirements for Measurement and Calibration Procedures for Space Solar Cells" was discussed with a focus on the scope of the document, a definition of primary standard cell, and required error analysis for all measurement techniques. Working groups addressed the issues of Air Mass Zero (AMO) solar constant and spectrum, laboratory measurement techniques, and te international round robin methodology. A summary is presented of the current state of each area and the formulation of the ISO document.

  16. Proceedings of the OECD/NEA/CSNI workshop on the implementation of hydrogen mitigation techniques

    International Nuclear Information System (INIS)

    Koroll, G.W.; Rohde, J.; Royen, J.

    1997-03-01

    The Workshop on the Implementation of Hydrogen Mitigation Techniques was held in Winnipeg, Manitoba,Canada from 1996 May 13 to 15. It was organized in collaboration with the Whiteshell Laboratories of Atomic Energy of Canada Limited (AECL), Ontario Hydro and the CANDU Owner's Group (COG). Sixty-five experts from twelve OECD Member countries and the Russian Federation attended the meeting. Papers presented in the sessions included topics: accident management and analysis, relevant aspects of hydrogen production, distribution and mixing, engineering, technology, possible side-effects consequences and new designs. The objectives of the Workshop were the following: to establish the state of the art of hydrogen mitigation techniques, with emphasis on igniters and catalytic recombiners; to exchange information on Member countries' strategies in managing hydrogen mitigation, and to establish dialogue as to differences in approach; to determine whether there is now an adequate technical basis for such strategies or whether more work is needed; to exchange information on future plans for implementation of hydrogen mitigation techniques

  17. 75 FR 76056 - FEDERAL REGISTER CITATION OF PREVIOUS ANNOUNCEMENT:

    Science.gov (United States)

    2010-12-07

    ... SECURITIES AND EXCHANGE COMMISSION Sunshine Act Meeting FEDERAL REGISTER CITATION OF PREVIOUS ANNOUNCEMENT: STATUS: Closed meeting. PLACE: 100 F Street, NE., Washington, DC. DATE AND TIME OF PREVIOUSLY ANNOUNCED MEETING: Thursday, December 9, 2010 at 2 p.m. CHANGE IN THE MEETING: Time change. The closed...

  18. Implant breast reconstruction after salvage mastectomy in previously irradiated patients.

    Science.gov (United States)

    Persichetti, Paolo; Cagli, Barbara; Simone, Pierfranco; Cogliandro, Annalisa; Fortunato, Lucio; Altomare, Vittorio; Trodella, Lucio

    2009-04-01

    The most common surgical approach in case of local tumor recurrence after quadrantectomy and radiotherapy is salvage mastectomy. Breast reconstruction is the subsequent phase of the treatment and the plastic surgeon has to operate on previously irradiated and manipulated tissues. The medical literature highlights that breast reconstruction with tissue expanders is not a pursuable option, considering previous radiotherapy a contraindication. The purpose of this retrospective study is to evaluate the influence of previous radiotherapy on 2-stage breast reconstruction (tissue expander/implant). Only patients with analogous timing of radiation therapy and the same demolitive and reconstructive procedures were recruited. The results of this study prove that, after salvage mastectomy in previously irradiated patients, implant reconstruction is still possible. Further comparative studies are, of course, advisable to draw any conclusion on the possibility to perform implant reconstruction in previously irradiated patients.

  19. Lightweight and Statistical Techniques for Petascale PetaScale Debugging

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Barton

    2014-06-30

    This project investigated novel techniques for debugging scientific applications on petascale architectures. In particular, we developed lightweight tools that narrow the problem space when bugs are encountered. We also developed techniques that either limit the number of tasks and the code regions to which a developer must apply a traditional debugger or that apply statistical techniques to provide direct suggestions of the location and type of error. We extend previous work on the Stack Trace Analysis Tool (STAT), that has already demonstrated scalability to over one hundred thousand MPI tasks. We also extended statistical techniques developed to isolate programming errors in widely used sequential or threaded applications in the Cooperative Bug Isolation (CBI) project to large scale parallel applications. Overall, our research substantially improved productivity on petascale platforms through a tool set for debugging that complements existing commercial tools. Previously, Office Of Science application developers relied either on primitive manual debugging techniques based on printf or they use tools, such as TotalView, that do not scale beyond a few thousand processors. However, bugs often arise at scale and substantial effort and computation cycles are wasted in either reproducing the problem in a smaller run that can be analyzed with the traditional tools or in repeated runs at scale that use the primitive techniques. New techniques that work at scale and automate the process of identifying the root cause of errors were needed. These techniques significantly reduced the time spent debugging petascale applications, thus leading to a greater overall amount of time for application scientists to pursue the scientific objectives for which the systems are purchased. We developed a new paradigm for debugging at scale: techniques that reduced the debugging scenario to a scale suitable for traditional debuggers, e.g., by narrowing the search for the root-cause analysis

  20. 28 CFR 10.5 - Incorporation of papers previously filed.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Incorporation of papers previously filed... CARRYING ON ACTIVITIES WITHIN THE UNITED STATES Registration Statement § 10.5 Incorporation of papers previously filed. Papers and documents already filed with the Attorney General pursuant to the said act and...

  1. Established and emerging methods for assessment of small and large intestinal motility

    DEFF Research Database (Denmark)

    Grønlund, D; Poulsen, J L; Sandberg, T H

    2017-01-01

    and validation of objective methods to evaluate motility of the whole gut is important. Such techniques may be applied in clinical settings as diagnostic tools, in research to elucidate underlying mechanisms of diseases, and to evaluate how the gut responds to various drugs. A wide array of such methods exists...... emerged, with the advantages that they are less invasive, use no radiation, and provide much more detailed information. PURPOSE: This review outlines well-established and emerging methods to evaluate small bowel and colonic motility in clinical settings and in research. The latter include the 3D...

  2. The application of a shift theorem analysis technique to multipoint measurements

    OpenAIRE

    M. E. Dieckmann; M. E. Dieckmann; S. C. Chapman

    1999-01-01

    A Fourier domain technique has been proposed previously which, in principle, quantifies the extent to which multipoint in-situ measurements can identify whether or not an observed structure is time stationary in its rest frame. Once a structure, sampled for example by four spacecraft, is shown to be quasi-stationary in its rest frame, the structure's velocity vector can be determined with respect to the sampling spacecraft. We investigate the properties of this technique, wh...

  3. Physical protection philosophy and techniques in Sweden

    International Nuclear Information System (INIS)

    Dufva, B.

    1988-01-01

    The circumstances for the protection of nuclear power plants are special in Sweden. A very important factor is that armed guards at the facilities are alien to the Swedish society. They do not use them. The Swedish concept of physical protection accepts that the aggressor will get into the facility. With this in mind, the Swedish Nuclear Power Inspectorate (SKI) has established the policy that administrative, technical, and organizational measures will be directed toward preventing an aggressor from damaging the reactor, even if he has occupied the facility. In addition, the best conditions possible shall be established for the operator and the police to reoccupy the plant. The author believes this policy is different from that of many other countries. Therefore, he focusses on the Swedish philosophy and techniques for the physical protection of nuclear power plants

  4. Kalijodo transformation in establishment of healthy environment in Jakarta

    Science.gov (United States)

    Sutanto, Erik; Junadi, Purnawan

    2018-03-01

    A good city setting can create a healthy environment. One of the structuring of cities that can create a healthy environment is the development of public space like Green Open Space (RTH) and Child-Friendly Integrated Public Space (RPTRA) such as in Kalijodo, Jakarta, Indonesia. The objective of building a public space in Kalijodo is to restore the functioning of the green zone in the area that previously used for housing residents and prostitution businesses to increase public space in Jakarta. The purpose of this study is to describe the formation of a healthy environment and the impact felt by users of this public space. The research method used in this research is descriptive qualitative with a phenomenological approach through interview, observation and documentation. There are three types of community activities in the public sphere, such as sports, children’s playground, and relaxation. The results show that the decline in crime rates and the presence of facilities and infrastructure in time to establish a healthy environment. The construction of facilities in the public spaces changes the image of Kalijodo from the previous place that has a negative image then turned into a positive image because the environment of Kalijodo became healthy. We also find that this changing image creates a positive spirit of the surrounding community and people are generally healthier and happier.

  5. An improved visualization-based force-measurement technique for short-duration hypersonic facilities

    Energy Technology Data Exchange (ETDEWEB)

    Laurence, Stuart J.; Karl, Sebastian [Institute of Aerodynamics and Flow Technology, Spacecraft Section, German Aerospace Center (DLR), Goettingen (Germany)

    2010-06-15

    This article is concerned with describing and exploring the limitations of an improved version of a recently proposed visualization-based technique for the measurement of forces and moments in short-duration hypersonic wind tunnels. The technique is based on tracking the motion of a free-flying body over a sequence of high-speed visualizations; while this idea is not new in itself, the use of high-speed digital cinematography combined with a highly accurate least-squares tracking algorithm allows improved results over what have been previously possible with such techniques. The technique precision is estimated through the analysis of artificially constructed and experimental test images, and the resulting error in acceleration measurements is characterized. For wind-tunnel scale models, position measurements to within a few microns are shown to be readily attainable. Image data from two previous experimental studies in the T5 hypervelocity shock tunnel are then reanalyzed with the improved technique: the uncertainty in the mean drag acceleration is shown to be reduced to the order of the flow unsteadiness, 2-3%, and time-resolved acceleration measurements are also shown to be possible. The response time of the technique for the configurations studied is estimated to be {proportional_to}0.5 ms. Comparisons with computations using the DLR TAU code also yield agreement to within the overall experimental uncertainty. Measurement of the pitching moment for blunt geometries still appears challenging, however. (orig.)

  6. Differential sensor in front photopyroelectric technique: II. Experimental

    International Nuclear Information System (INIS)

    Ivanov, R; Moreno, I; Araujo-Andrade, C; MarIn, E; Cruz-Orea, A; Pichardo-Molina, J L

    2009-01-01

    We describe the differential cell design and the experimental (optical and electronic) setup for the differential front photopyroelectric technique, whose theory has been developed in the first part of this paper (Ivanov et al 2008 J. Phys. D: Appl. Phys. 41 085106). We will show first how the direct (non-differential) front photopyroelectric theory described in our previous paper reproduces well the experimental results. The usefulness of the differential technique is demonstrated by means of experimental measurements of the thermal effusivity in binary ethanol-water and glycerol-water mixtures, based on a theoretical methodology that simplifies the measurement procedure and diminishes the experimental uncertainty.

  7. Differential sensor in front photopyroelectric technique: II. Experimental

    Energy Technology Data Exchange (ETDEWEB)

    Ivanov, R; Moreno, I; Araujo-Andrade, C [Facultad de Fisica, Universidad Autonoma de Zacatecas, Calz. Solidaridad Esquina Paseo de la Bufa s/n, CP 98060, Zacatecas, Zac. (Mexico); MarIn, E [Centro de Investigacion en Ciencia Aplicada y TecnologIa Avanzada-Instituto Politecnico Nacional, Legaria 694, Col. Irrigacion, CP 11500, Mexico D.F. (Mexico); Cruz-Orea, A [Departamento de Fisica, CINVESTAV-IPN, Av. IPN No. 2508, Col. San Pedro Zacatenco, CP 07360, Mexico D.F. (Mexico); Pichardo-Molina, J L, E-mail: rumen@fisica.uaz.edu.m [Centro de Investigaciones en Optica, Loma del Bosque 115, Loma del Campestre, CP 37150, Leon, Guanajuato (Mexico)

    2009-06-21

    We describe the differential cell design and the experimental (optical and electronic) setup for the differential front photopyroelectric technique, whose theory has been developed in the first part of this paper (Ivanov et al 2008 J. Phys. D: Appl. Phys. 41 085106). We will show first how the direct (non-differential) front photopyroelectric theory described in our previous paper reproduces well the experimental results. The usefulness of the differential technique is demonstrated by means of experimental measurements of the thermal effusivity in binary ethanol-water and glycerol-water mixtures, based on a theoretical methodology that simplifies the measurement procedure and diminishes the experimental uncertainty.

  8. Colorimetry Technique for Scalable Characterization of Suspended Graphene.

    Science.gov (United States)

    Cartamil-Bueno, Santiago J; Steeneken, Peter G; Centeno, Alba; Zurutuza, Amaia; van der Zant, Herre S J; Houri, Samer

    2016-11-09

    Previous statistical studies on the mechanical properties of chemical-vapor-deposited (CVD) suspended graphene membranes have been performed by means of measuring individual devices or with techniques that affect the material. Here, we present a colorimetry technique as a parallel, noninvasive, and affordable way of characterizing suspended graphene devices. We exploit Newton's rings interference patterns to study the deformation of a double-layer graphene drum 13.2 μm in diameter when a pressure step is applied. By studying the time evolution of the deformation, we find that filling the drum cavity with air is 2-5 times slower than when it is purged.

  9. Development of techniques for monitoring corrosion in Magnox plant

    International Nuclear Information System (INIS)

    Haines, N.F.; Whittle, I.; Wilson, R.

    1974-01-01

    Steel oxidation in Magnox reactors has led to the development of techniques for measuring oxide thicknesses. An account is given of the methods used by the CEGB for making non-destructive measurements of oxide coatings both in the laboratory and remotely in the core regions of reactors. Specific techniques include β back-scattering which is compared with conventional microscope or weight gain methods for particular applications. The laser corrosion monitor and an ultrasonic method are described and compared as in-reactor techniques. An eddy current method is being developed for reactor regions where access is extremely restricted. A discussion considers the effect of oxide form upon the response of the instruments. The necessary further work is described which establishes the usefulness of each instrument over a range of oxide thicknesses and steels of different physical properties. (author)

  10. Criteria and evaluation of three decontamination techniques

    Energy Technology Data Exchange (ETDEWEB)

    Tripp, J.L.

    1994-01-01

    Past decontamination and solvent recovery activities at the Idaho Chemical Processing Plant (ICPP), which is part of the Idaho National Engineering Laboratory (INEL), have resulted in the accumulation of 1.5 million gallons of radioactively contaminated sodium-bearing liquid waste. Future decontamination activities at the ICPP could result in the production of 5 million gallons or more of sodium-bearing waste using the current decontamination techniques of chemical/water flushes and steam jet cleaning. This waste requires a large amount of cold chemical additive to process because the low melting temperatures of sodium and potassium salts cause agglomeration in the bed of the calciner vessel. Criteria have been established for evaluating methods and technologies available for decontaminating equipment and facilities. The criteria were weighted according to their relative importance using a Kepner-Tregoe Problem Solving process. These criteria were used to rank three decontamination techniques new to the ICPP: laser ablation, liquid abrasive blasting and CO{sub 2} pellet blasting, against the standard decontamination techniques of sodium-based chemical cleaning and water/steam jets used.

  11. Criteria and evaluation of three decontamination techniques

    International Nuclear Information System (INIS)

    Tripp, J.L.

    1994-01-01

    Past decontamination and solvent recovery activities at the Idaho Chemical Processing Plant (ICPP), which is part of the Idaho National Engineering Laboratory (INEL), have resulted in the accumulation of 1.5 million gallons of radioactively contaminated sodium-bearing liquid waste. Future decontamination activities at the ICPP could result in the production of 5 million gallons or more of sodium-bearing waste using the current decontamination techniques of chemical/water flushes and steam jet cleaning. This waste requires a large amount of cold chemical additive to process because the low melting temperatures of sodium and potassium salts cause agglomeration in the bed of the calciner vessel. Criteria have been established for evaluating methods and technologies available for decontaminating equipment and facilities. The criteria were weighted according to their relative importance using a Kepner-Tregoe Problem Solving process. These criteria were used to rank three decontamination techniques new to the ICPP: laser ablation, liquid abrasive blasting and CO 2 pellet blasting, against the standard decontamination techniques of sodium-based chemical cleaning and water/steam jets used

  12. Establishing gene models from the Pinus pinaster genome using gene capture and BAC sequencing.

    Science.gov (United States)

    Seoane-Zonjic, Pedro; Cañas, Rafael A; Bautista, Rocío; Gómez-Maldonado, Josefa; Arrillaga, Isabel; Fernández-Pozo, Noé; Claros, M Gonzalo; Cánovas, Francisco M; Ávila, Concepción

    2016-02-27

    In the era of DNA throughput sequencing, assembling and understanding gymnosperm mega-genomes remains a challenge. Although drafts of three conifer genomes have recently been published, this number is too low to understand the full complexity of conifer genomes. Using techniques focused on specific genes, gene models can be established that can aid in the assembly of gene-rich regions, and this information can be used to compare genomes and understand functional evolution. In this study, gene capture technology combined with BAC isolation and sequencing was used as an experimental approach to establish de novo gene structures without a reference genome. Probes were designed for 866 maritime pine transcripts to sequence genes captured from genomic DNA. The gene models were constructed using GeneAssembler, a new bioinformatic pipeline, which reconstructed over 82% of the gene structures, and a high proportion (85%) of the captured gene models contained sequences from the promoter regulatory region. In a parallel experiment, the P. pinaster BAC library was screened to isolate clones containing genes whose cDNA sequence were already available. BAC clones containing the asparagine synthetase, sucrose synthase and xyloglucan endotransglycosylase gene sequences were isolated and used in this study. The gene models derived from the gene capture approach were compared with the genomic sequences derived from the BAC clones. This combined approach is a particularly efficient way to capture the genomic structures of gene families with a small number of members. The experimental approach used in this study is a valuable combined technique to study genomic gene structures in species for which a reference genome is unavailable. It can be used to establish exon/intron boundaries in unknown gene structures, to reconstruct incomplete genes and to obtain promoter sequences that can be used for transcriptional studies. A bioinformatics algorithm (GeneAssembler) is also provided as a

  13. International cooperative research with Japan for the establishment of cooperation structure and technology for dynamic neutron radiography using HANARO

    International Nuclear Information System (INIS)

    Lim, I. C.; Sim, C. M.; Lee, B. H.; Choi, Y. S.; Baek, W. P.; Cha, J. E.; Yoon, B. J.; Chu, I. C.

    2007-07-01

    DNR is the technique to obtain radiography image continuously using a imaging system and Japan is the leading country in this field. Considering that no research has been performed to obtain quantitative parameters using DNR in Korea, it was necessary to establish a cooperative structure with Japanese experts and to develop the DNR technique throughout this project. The objectives of the project were to conduct 4 cooperative experiments using the HANARO BNCT facility and to establish a relationship with Japanese experts which makes it possible to maintain continuous communication. 4 experiments such as the void fraction and flow pattern measurement in a channel simulating HANARO fuel channel, observation of flow field in Pb/Bi field and the observation of cavity in a diesel engine nozzle were successfully completed. Also, the continuos communication and cooperation between the experts of two countries will be made. In this sense, this project is believed as a model project to use the mega research facility such as HANARO for the international cooperation

  14. Left thoracotomy HeartWare implantation with outflow graft anastomosis to the descending aorta: a simplified bridge for patients with multiple previous sternotomies.

    Science.gov (United States)

    Umakanthan, Ramanan; Haglund, Nicholas A; Stulak, John M; Joyce, Lyle D; Ahmad, Rashid; Keebler, Mary E; Maltais, Simon

    2013-01-01

    Advances in mechanical circulatory support have been critical in bridging patients awaiting heart transplantation. In addition, improvement in device durability has enabled left ventricular assist device therapy to be applied as destination therapy in those not felt to be transplant candidate. Because of the increasing complexity of patients, there continues to be a need for alternative strategies for device implantation to bridge high-risk patients awaiting heart transplantation, wherein the risks of numerous previous sternotomies may be prohibitive. We present a unique technique for placement of the HeartWare ventricular assist device via left anterior thoracotomy to the descending aorta in a patient awaiting heart transplantation with a history of multiple previous sternotomies.

  15. No discrimination against previous mates in a sexually cannibalistic spider

    Science.gov (United States)

    Fromhage, Lutz; Schneider, Jutta M.

    2005-09-01

    In several animal species, females discriminate against previous mates in subsequent mating decisions, increasing the potential for multiple paternity. In spiders, female choice may take the form of selective sexual cannibalism, which has been shown to bias paternity in favor of particular males. If cannibalistic attacks function to restrict a male's paternity, females may have little interest to remate with males having survived such an attack. We therefore studied the possibility of female discrimination against previous mates in sexually cannibalistic Argiope bruennichi, where females almost always attack their mate at the onset of copulation. We compared mating latency and copulation duration of males having experienced a previous copulation either with the same or with a different female, but found no evidence for discrimination against previous mates. However, males copulated significantly shorter when inserting into a used, compared to a previously unused, genital pore of the female.

  16. Establishment of a dosimetry method for the exposure evaluation to the ultraviolet radiation

    International Nuclear Information System (INIS)

    Gronchi, Claudia Carla

    2009-01-01

    A dosimetric method for the exposure evaluation to ultraviolet radiation was established with Al 2 O 3 :C InLight detectors and an OSL microStar reader and software, of Landauer, associated to the techniques of Optically Stimulated Luminescence (OSL) and Photo transferred Optically Stimulated Luminescence (PTOSL). The main phases of this work were: characterization of the Al 2 O 3 :C InLight detectors, without pre-conditioning, exposed to ultraviolet radiation (RUV) of solar and artificial sources, using the OSL technique; characterization of the Al 2 O 3 :C InLight detectors, pre-conditioned, exposed to RUV solar and artificial sources, using the PTOSL technique; practical applications of the Al 2 O 3 :C InLight detectors to the solar and artificial RUV, originating from TIG (Tungsten Inert Gas) and electric welding. The Al 2 O 3 :C InLight detectors presented satisfactory OSL and PTOSL responses in relation to the parameters: wavelength, UV illumination time, irradiance, radiance exposure and angular dependence to the RUV. Those detectors presented maximum OSL and PTOSL stimulation for the wavelength of 330 nm, showing that they are may be useful for UVA radiation detection and dosimetry. (author)

  17. High-precision numerical simulation with autoadaptative grid technique in nonlinear thermal diffusion

    International Nuclear Information System (INIS)

    Chambarel, A.; Pumborios, M.

    1992-01-01

    This paper reports that many engineering problems concern the determination of a steady state solution in the case with strong thermal gradients, and results obtained using the finite-element technique are sometimes inaccurate, particularly for nonlinear problems with unadapted meshes. Building on previous results in linear problems, we propose an autoadaptive technique for nonlinear cases that uses quasi-Newtonian iterations to reevaluate an interpolation error estimation. The authors perfected an automatic refinement technique to solve the nonlinear thermal problem of temperature calculus in a cast-iron cylinder head of a diesel engine

  18. ELECTRONIC SYSTEM FOR EXPERIMENTATION IN AC ELECTROGRAVIMETRY I: TECHNIQUE FUNDAMENTALS

    Directory of Open Access Journals (Sweden)

    Róbinson Torres

    Full Text Available Basic fundamentals of AC electrogravimetry are introduced. Their main requirements and characteristics are detailed to establish the design of an electronic system that allows the appropriate extraction of data needed to determine the electrogravimetric transfer function (EGTF and electrochemical impedance (EI, in an experimental set-up for the AC electrogravimetry technique.

  19. Reliability of single kidney glomerular filtration rate measured by a 99mTc-DTPA gamma camera technique

    International Nuclear Information System (INIS)

    Rehling, M.; Moller, M.L.; Jensen, J.J.; Thamdrup, B.; Lund, J.O.; Trap-Jensen, J.

    1986-01-01

    The reliability of a previously published method for determination of single kidney glomerular filtration rate (SKGFR) by means of technetium-99m-diethylenetriaminepenta-acetate (99mTc-DTPA) gamma camera renography was evaluated. The day-to-day variation in the calculated SKGFR values was earlier found to be 8.8%. The technique was compared to the simultaneously measured renal clearance of inulin in 19 unilaterally nephrectomized patients with GFR varying from 11 to 76 ml/min. The regression line (y = 1.04 X -2.5) did not differ significantly from the line of identity. The standard error of estimate was 4.3 ml/min. In 17 patients the inter- and intraobserver variation of the calculated SKGFR values was 1.2 ml/min and 1.3 ml/min, respectively. In 21 of 25 healthy subjects studied (age range 27-29 years), total GFR calculated from the renograms was within an established age-dependent normal range of GFR

  20. An overview of environmental pollution and monitoring techniques

    International Nuclear Information System (INIS)

    Qureshi, I.H.

    1997-01-01

    Environmental pollution has become a world-wide concern as it is likely to affect the ecological system and human health. The indiscriminate release of harmful chemicals and toxic heavy metals in the environment by industrial, agricultural and other activities of man may adversely affect the quality of our air, water and food resources. These toxic chemicals may find their way to living organisms and human body through food chain and may induce various metabolic disorders. It is, therefore, necessary to assess the quality of environment by measuring the concentration of pollutants in air, water, soil and food materials and to establish base-line level. Since the pollutants are present in extremely small amounts, sensitive and accurate analytical techniques have to be employed to obtain reliable data. Studies on the measurement of essential and toxic inorganic elements in various food items and other materials have been carried out at PINSTECH with a view to assess the safety of diet and to establish baseline values. These values will he helpful, in future, to monitor the degree of pollution and to suggest possible remedial and control measures. The estimation of some of the inorganic pollutants and the techniques used in our laboratories and briefly discussed. (author)

  1. Transformer Incipient Fault Prediction Using Combined Artificial Neural Network and Various Particle Swarm Optimisation Techniques.

    Directory of Open Access Journals (Sweden)

    Hazlee Azil Illias

    Full Text Available It is important to predict the incipient fault in transformer oil accurately so that the maintenance of transformer oil can be performed correctly, reducing the cost of maintenance and minimise the error. Dissolved gas analysis (DGA has been widely used to predict the incipient fault in power transformers. However, sometimes the existing DGA methods yield inaccurate prediction of the incipient fault in transformer oil because each method is only suitable for certain conditions. Many previous works have reported on the use of intelligence methods to predict the transformer faults. However, it is believed that the accuracy of the previously proposed methods can still be improved. Since artificial neural network (ANN and particle swarm optimisation (PSO techniques have never been used in the previously reported work, this work proposes a combination of ANN and various PSO techniques to predict the transformer incipient fault. The advantages of PSO are simplicity and easy implementation. The effectiveness of various PSO techniques in combination with ANN is validated by comparison with the results from the actual fault diagnosis, an existing diagnosis method and ANN alone. Comparison of the results from the proposed methods with the previously reported work was also performed to show the improvement of the proposed methods. It was found that the proposed ANN-Evolutionary PSO method yields the highest percentage of correct identification for transformer fault type than the existing diagnosis method and previously reported works.

  2. Transformer Incipient Fault Prediction Using Combined Artificial Neural Network and Various Particle Swarm Optimisation Techniques.

    Science.gov (United States)

    Illias, Hazlee Azil; Chai, Xin Rui; Abu Bakar, Ab Halim; Mokhlis, Hazlie

    2015-01-01

    It is important to predict the incipient fault in transformer oil accurately so that the maintenance of transformer oil can be performed correctly, reducing the cost of maintenance and minimise the error. Dissolved gas analysis (DGA) has been widely used to predict the incipient fault in power transformers. However, sometimes the existing DGA methods yield inaccurate prediction of the incipient fault in transformer oil because each method is only suitable for certain conditions. Many previous works have reported on the use of intelligence methods to predict the transformer faults. However, it is believed that the accuracy of the previously proposed methods can still be improved. Since artificial neural network (ANN) and particle swarm optimisation (PSO) techniques have never been used in the previously reported work, this work proposes a combination of ANN and various PSO techniques to predict the transformer incipient fault. The advantages of PSO are simplicity and easy implementation. The effectiveness of various PSO techniques in combination with ANN is validated by comparison with the results from the actual fault diagnosis, an existing diagnosis method and ANN alone. Comparison of the results from the proposed methods with the previously reported work was also performed to show the improvement of the proposed methods. It was found that the proposed ANN-Evolutionary PSO method yields the highest percentage of correct identification for transformer fault type than the existing diagnosis method and previously reported works.

  3. Transformer Incipient Fault Prediction Using Combined Artificial Neural Network and Various Particle Swarm Optimisation Techniques

    Science.gov (United States)

    2015-01-01

    It is important to predict the incipient fault in transformer oil accurately so that the maintenance of transformer oil can be performed correctly, reducing the cost of maintenance and minimise the error. Dissolved gas analysis (DGA) has been widely used to predict the incipient fault in power transformers. However, sometimes the existing DGA methods yield inaccurate prediction of the incipient fault in transformer oil because each method is only suitable for certain conditions. Many previous works have reported on the use of intelligence methods to predict the transformer faults. However, it is believed that the accuracy of the previously proposed methods can still be improved. Since artificial neural network (ANN) and particle swarm optimisation (PSO) techniques have never been used in the previously reported work, this work proposes a combination of ANN and various PSO techniques to predict the transformer incipient fault. The advantages of PSO are simplicity and easy implementation. The effectiveness of various PSO techniques in combination with ANN is validated by comparison with the results from the actual fault diagnosis, an existing diagnosis method and ANN alone. Comparison of the results from the proposed methods with the previously reported work was also performed to show the improvement of the proposed methods. It was found that the proposed ANN-Evolutionary PSO method yields the highest percentage of correct identification for transformer fault type than the existing diagnosis method and previously reported works. PMID:26103634

  4. Evidence required for establishing the absence of tsetse and trypanosomosis associated with tsetse eradication programmes

    International Nuclear Information System (INIS)

    McDermott, J.J.

    2000-01-01

    This paper considers entomological and epidemiological criteria for establishing the absence of tsetse and trypanosomosis associated with tsetse eradication programmes. The sampling goal is simple - to maximise the probability of detecting tsetse flies in the field or trypanosomes in hosts, if they exist. Sampling strategies cannot guarantee the absence of tsetse and trypanosomes but they can be used to estimate the probability of their eradication. Because tsetse eradication programmes are targeted at defined areas, geographical information system (GIS) tools are very useful in guiding spatial sampling strategies. Two approaches to assess tsetse eradication are discussed. The first depends only on information on the sensitivity of tsetse trapping methods used. The second combines information on pre-eradication tsetse trapping and the proportion of time during which no tsetse have been trapped, assuming either a stable or declining (preferred) pre-eradication tsetse population. For establishing the absence of trypanosomosis in host populations, there are standard sampling techniques that can be adjusted for the sensitivity and specificity of the trypanosome detection methods used. Required sample sizes can be calculated for both direct trypanosome detection methods of 100% specificity or indirect tests with imperfect sensitivity and specificity. For the latter, both the sample size and the number of reactors (assumed to be false positive) are estimated for the required confidence level. These entomological and epidemiological methods were then applied to assess the eradication of tsetse and trypanosomosis from Unguja island of Zanzibar using the sterile insect technique (SIT). Pre- and post-eradication data collected were sufficient to establish with 95% confidence that both tsetse and trypanosomosis were eradicated. (author)

  5. Establishing a PWR burn-up library

    International Nuclear Information System (INIS)

    Lutz, D.C.

    1981-01-01

    Starting out from data file ENDF/B IV /1/, a cross-section library has been established for the calculation of operating conditions in pressurized water reactors of the type used in BIBLIS B. The library includes macroscopic, homogenized 2-group cross-sections for all types of fuel elements used in this reactor, including those equipped with boron glass rods. For their calculation the previous irradiation of the fuel has been taken into consideration by approximation. Information on fuel consumption from cell burn-up calculations has been stored in a separate data file. It was designed as a base for the determination of cross sections to be used in the calculation of the incident ''main-steam pipe fracture''. For this library the description of cross sections as a function of the moderator status chose the water densities at 300 0 C/155 bar, 190 0 C/140 bar and 100 0 C/100 bar as fixed values. The burn-up library has been tested by a three-dimensional calculation for the 1sup(st) cycle of the BIBLIS B-reactor using program QUABOX /2/. This showed variances with the anticipated course concerning critically, which can be explained almost quantitatively by known deficiencies of the ENDF/b-IV library. (orig.) [de

  6. Genetic algorithms - A new technique for solving the neutron spectrum unfolding problem

    International Nuclear Information System (INIS)

    Freeman, David W.; Edwards, D. Ray; Bolon, Albert E.

    1999-01-01

    A new technique utilizing genetic algorithms has been applied to the Bonner sphere neutron spectrum unfolding problem. Genetic algorithms are part of a relatively new field of 'evolutionary' solution techniques that mimic living systems with computer-simulated 'chromosome' solutions. Solutions mate and mutate to create better solutions. Several benchmark problems, considered representative of radiation protection environments, have been evaluated using the newly developed UMRGA code which implements the genetic algorithm unfolding technique. The results are compared with results from other well-established unfolding codes. The genetic algorithm technique works remarkably well and produces solutions with relatively high spectral qualities. UMRGA appears to be a superior technique in the absence of a priori data - it does not rely on 'lucky' guesses of input spectra. Calculated personnel doses associated with the unfolded spectra match benchmark values within a few percent

  7. Clinical potential of boron neutron capture therapy for locally recurrent inoperable previously irradiated head and neck cancer

    International Nuclear Information System (INIS)

    Lim, Diana; Quah, Daniel SC; Leech, Michelle; Marignol, Laure

    2015-01-01

    This review compares the safety and efficacy of boron neutron capture therapy (BNCT) in the treatment of previously irradiated, inoperable locoregional recurrent HNC patients and compares BNCT against the standard treatment of platinum-based chemotherapy. Our analysis of published clinical trials highlights efficacy of BNCT associated with mild side effects. However, the use of BNCT should be explored in stratified randomised trials. - Highlights: • BNCT can prolong median overall survival. • BNCT can be associated with severe adverse effects. • BNCT may be comparable to chemotherapy-based regimens. • BNCT may be comparable to re-irradiation techniques regimens in patients with low performance status.

  8. Camphor: a good model for illustrating NMR techniques; Canfora: um bom modelo para ilustrar tecnicas de RMN

    Energy Technology Data Exchange (ETDEWEB)

    Yoneda, Julliane Diniz; Leal, Katia Zaccur [Universidade Federal Fluminense (UFF), Niteroi, RJ (Brazil). Dept. de Fisico-Quimica]. E-mail: kzl@rmn.uff.br; Seidl, Peter Rudolf [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Escola de Quimica. Dept. de Processos Organicos; Azeredo, Rodrigo Bagueira de V. [Universidade Federal Fluminense (UFF), Niteroi, RJ (Brazil). Inst. de Quimica. Dept. de Quimica Organica; Kleinpeter, Erich [Universitaet Potsdam (Germany). Chemisches Institut

    2007-07-01

    The use of Nuclear Magnetic Resonance spectroscopy to establish the three-dimensional structures of molecules is an important component of modern Chemistry courses. The combination of techniques that can be used for this purpose is conveniently illustrated by their application to the camphor molecule. This paper presents applications of several techniques used in NMR spectral interpretation in an increasing order of complexity. The result of individual experiments is illustrated in order to familiarize the user with the way connectivity through bonds and through space is established from 1D/2D-NMR spectra and molecular stereochemistry is determined from different NMR experiments. (author)

  9. Microvascular imaging: techniques and opportunities for clinical physiological measurements

    International Nuclear Information System (INIS)

    Allen, John; Howell, Kevin

    2014-01-01

    The microvasculature presents a particular challenge in physiological measurement because the vessel structure is spatially inhomogeneous and perfusion can exhibit high variability over time. This review describes, with a clinical focus, the wide variety of methods now available for imaging of the microvasculature and their key applications. Laser Doppler perfusion imaging and laser speckle contrast imaging are established, commercially-available techniques for determining microvascular perfusion, with proven clinical utility for applications such as burn-depth assessment. Nailfold capillaroscopy is also commercially available, with significant published literature that supports its use for detecting microangiopathy secondary to specific connective tissue diseases in patients with Raynaud's phenomenon. Infrared thermography measures skin temperature and not perfusion directly, and it has only gained acceptance for some surgical and peripheral microvascular applications. Other emerging technologies including imaging photoplethysmography, optical coherence tomography, photoacoustic tomography, hyperspectral imaging, and tissue viability imaging are also described to show their potential as techniques that could become established tools for clinical microvascular assessment. Growing interest in the microcirculation has helped drive the rapid development in perfusion imaging of the microvessels, bringing exciting opportunities in microvascular research. (topical review)

  10. A study on the hollow-out radiation technique applied to the protection of the spinal cord

    International Nuclear Information System (INIS)

    Matsuda, Tadayoshi

    1975-01-01

    The hollow-out radiation technique to protect the spinal cord in linear accelerator X-ray treatment of malignant diseases has been established in this study. Several kinds of diseases were selected as the subjects of the hollow-out technique to protect the cervical spinal cord, thoracic spinal cord, and dorsolumbar spinal cord from radiation, plus fundamental data, such as the materials, shapes and sizes of absorber, which are most appropriate for each of the diseases, were established. In all the cases receiving this technique, the necessary areas of therapy are covered by 80-90% dose distribution and the radiation dose of the spinal cord is kept below 40%. The fundamental data and irradiation conditions for the hollow-out technique of every part of the spinal cord were arranged from the results of phantom examinations on every part of the human body and from 42 cases actually treated. In the present study, the hollow-out technique for the cervical spinal cord, thoracic spinal cord, and dorsolumbar spinal cord is divided into 5 categories, and a method for the planning of radiation therapy and the actual treatment are described. The hollow-out radiation technique on the spinal cord is useful radiation therapy which can give better results by preventing radiation myelopathy. (auth.)

  11. A previous hamstring injury affects kicking mechanics in soccer players.

    Science.gov (United States)

    Navandar, Archit; Veiga, Santiago; Torres, Gonzalo; Chorro, David; Navarro, Enrique

    2018-01-10

    Although the kicking skill is influenced by limb dominance and sex, how a previous hamstring injury affects kicking has not been studied in detail. Thus, the objective of this study was to evaluate the effect of sex and limb dominance on kicking in limbs with and without a previous hamstring injury. 45 professional players (males: n=19, previously injured players=4, age=21.16 ± 2.00 years; females: n=19, previously injured players=10, age=22.15 ± 4.50 years) performed 5 kicks each with their preferred and non-preferred limb at a target 7m away, which were recorded with a three-dimensional motion capture system. Kinematic and kinetic variables were extracted for the backswing, leg cocking, leg acceleration and follow through phases. A shorter backswing (20.20 ± 3.49% vs 25.64 ± 4.57%), and differences in knee flexion angle (58 ± 10o vs 72 ± 14o) and hip flexion velocity (8 ± 0rad/s vs 10 ± 2rad/s) were observed in previously injured, non-preferred limb kicks for females. A lower peak hip linear velocity (3.50 ± 0.84m/s vs 4.10 ± 0.45m/s) was observed in previously injured, preferred limb kicks of females. These differences occurred in the backswing and leg-cocking phases where the hamstring muscles were the most active. A variation in the functioning of the hamstring muscles and that of the gluteus maximus and iliopsoas in the case of a previous injury could account for the differences observed in the kicking pattern. Therefore, the effects of a previous hamstring injury must be considered while designing rehabilitation programs to re-educate kicking movement.

  12. Establishing experimental model of human internal carotid artery siphon segment in canine common carotid artery

    International Nuclear Information System (INIS)

    Cui Xuee; Li Minghua; Wang Yongli; Cheng Yingsheng; Li Wenbin

    2005-01-01

    Objective: To study the feasibility of establishing experimental model of human internal carotid artery siphon segment in canine common carotid artery (CCA) by end-to-end anastomoses of one side common carotid artery segment with the other side common carotid artery. Methods: Surgical techniques were used to make siphon model in 8 canines. One side CCA was taken as the parent artery and anastomosing with the cut off contra-lateral CCA segment which has passed through within the S-shaped glass tube. Two weeks after the creation of models angiography showed the model siphons were patent. Results: Experimental models of human internal carotid artery siphon segment were successfully made in all 8 dogs. Conclusions: It is practically feasible to establish experimental canine common carotid artery models of siphon segment simulating human internal carotid artery. (authors)

  13. The use of coal refuse bike substratoun in cultivate techniques without soils; Utilizacion de los Esteriles de Carbon como Sustratos en Cultivos sin Suelo 2 Fase

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-11-01

    Coal refuse poses several problems as regards both their storage and environmental impact: landscape alteration, pollution, high costs, an increasing difficulty in finding appropriate places for storage, etc. Therefore, the companies HUMOSA, HORPLASA and the C. S. I. C. Centre for Environmental Sciences carried out a joint study financed by OCICARBON. This study, completing other ones carried out previously, was aimed at determining the use as both a soilless medium for growing other vegetables than tomatoes and a basic component for container gardening. Then, based on previous experiments, two types of coal refuse were selected: coal refuse from dumps and burnt coal refuse. The characterization of the coal refuse was carried out and the investigation-line was established: (I) the adaption of techniques and know-how obtained up to that moment to the production of kidney beans faba de la granja, green beans and pepper; (II) to study the possibilities of coal refuse as basic components of substrates for container gardening of decorative outdoor plants different from the already investigated conifers in order examine thoroughly the cultivation techniques and, in particular, the methods of fertilization by irrigation. Exhaustive controls were carried out with both types of cultivation using as reference other cultivations with conventional substrates. The results obtained proved that coal refuse can be used as soilles growing medium for vegetables and for container gardening of decorative plants.

  14. Subsequent childbirth after a previous traumatic birth.

    Science.gov (United States)

    Beck, Cheryl Tatano; Watson, Sue

    2010-01-01

    Nine percent of new mothers in the United States who participated in the Listening to Mothers II Postpartum Survey screened positive for meeting the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria for posttraumatic stress disorder after childbirth. Women who have had a traumatic birth experience report fewer subsequent children and a longer length of time before their second baby. Childbirth-related posttraumatic stress disorder impacts couples' physical relationship, communication, conflict, emotions, and bonding with their children. The purpose of this study was to describe the meaning of women's experiences of a subsequent childbirth after a previous traumatic birth. Phenomenology was the research design used. An international sample of 35 women participated in this Internet study. Women were asked, "Please describe in as much detail as you can remember your subsequent pregnancy, labor, and delivery following your previous traumatic birth." Colaizzi's phenomenological data analysis approach was used to analyze the stories of the 35 women. Data analysis yielded four themes: (a) riding the turbulent wave of panic during pregnancy; (b) strategizing: attempts to reclaim their body and complete the journey to motherhood; (c) bringing reverence to the birthing process and empowering women; and (d) still elusive: the longed-for healing birth experience. Subsequent childbirth after a previous birth trauma has the potential to either heal or retraumatize women. During pregnancy, women need permission and encouragement to grieve their prior traumatic births to help remove the burden of their invisible pain.

  15. ArthroBroström Lateral Ankle Stabilization Technique: An Anatomic Study.

    Science.gov (United States)

    Acevedo, Jorge I; Ortiz, Cristian; Golano, Pau; Nery, Caio

    2015-10-01

    Arthroscopic ankle lateral ligament repair techniques have recently been developed and biomechanically as well as clinically validated. Although there has been 1 anatomic study relating suture and anchor proximity to anatomic structures, none has evaluated the ArthroBroström procedure. To evaluate the proximity of anatomic structures for the ArthroBroström lateral ankle ligament stabilization technique and to define ideal landmarks and "safe zones" for this repair. Descriptive laboratory study. Ten human cadaveric ankle specimens (5 matched pairs) were screened for the study. All specimens underwent arthroscopic lateral ligament repair according to the previously described ArthroBroström technique with 2 suture anchors in the fibula. Three cadaveric specimens were used to test the protocol, and 7 were dissected to determine the proximity of anatomic structures. Several distances were measured, including those of different anatomic structures to the suture knots, to determine the "safe zones." Measurements were obtained by 2 separate observers, and statistical analysis was performed. None of the specimens revealed entrapment by either of the suture knots of the critical anatomic structures, including the superficial peroneal nerve (SPN), sural nerve, peroneus tertius tendon, peroneus brevis tendon, or peroneus longus tendon. The internervous safe zone between the intermediate branch of the SPN and sural nerve was a mean of 51 mm (range, 39-64 mm). The intertendinous safe zone between the peroneus tertius and peroneus brevis was a mean of 43 mm (range, 37-49 mm). On average, a 20-mm (range, 8-36 mm) safe distance was maintained from the most medial suture to the intermediate branch of the SPN. The amount of inferior extensor retinaculum (IER) grasped by either suture knot varied from 0 to 12 mm, with 86% of repairs including the retinaculum. The results indicate that there is a relatively wide internervous and intertendinous safe zone when performing the Arthro

  16. Detection of radiation deformation in crystalline polymers using the speckle photography technique

    International Nuclear Information System (INIS)

    El-Ghandoor, H.; Hashem, A.A.; Sharaf, F.

    1995-01-01

    In order to measure the resulting deformation due to gamma irradiation of polymers, a new optical technique, namely speckle-photography, was established and used. Thin films of tetrafluoroethene, with constant thickness were irradiated by different doses of gamma rays and the diffraction patterns of a laser beam passing through these films were recorded using the speckle photography technique. This technique has been applied to detect the radiation deformation in (Teflon) TFE, which is a crystalline polymer. A diffraction pattern due to the TFE thin layer is obtained and superimposed on the interference pattern displaying the speckle pattern pairs recorded on the same emulsion. (author)

  17. The preparation of aneurysm model in rabbits by vessel ligation and elastase-induced technique

    International Nuclear Information System (INIS)

    Lu Chuan; Xie Qianyu; Liu Linxiang

    2010-01-01

    Objective: To establish an aneurysm model, which is quite similar to the human intracranial aneurysm in morphology, in rabbits by means of vessel ligation together with elastase-induced technique. Methods: Sixteen New Zealand white rabbits were used in this study. Distal carotid ligation and intraluminal elastase incubation was employed in ten rabbits (study group) to create aneurysm on the right common carotid artery. And surgical suture of a segment of the left carotid common artery was carried out in six rabbits (used as control group) to establish the aneurysm model. DSA exam of the created aneurysms by using catheterization via femoral artery was performed at one week and at one month after surgery. The patency, morphology and pathology of the aneurysms were observed. The results were statistically analyzed. Results: The aneurysms in both groups remained patent after they were created. Angiography one week after the surgery showed that all the aneurysms in study group were patent, while in control group only two aneurysms showed opacification with contrast medium and the remaining four aneurysms were all occluded. DSA at one month after the procedure demonstrated that all the aneurysms in study group remained patent, and the previous two patent aneurysms in control group became occluded. The mean width and length of the aneurysmal cavity in study group immediately after the procedure were (3.70 ± 0.16) mm and (6.53 ± 0.65) mm respectively, which enlarged to (5.06 ± 0.31) mm and (9.0 ± 0.52) mm respectively one month after the surgery. The difference in size changes was statistically significant (P < 0.05). Pathologically, almost complete absence of the internal elastic lamina and medial wall elastin of the aneurysms was observed. Conclusion: The aneurysm model prepared with vessel ligation together with elastase-induced technique carries high patent rate and possesses the feature of spontaneous growing, moreover, its morphology is quite similar to the

  18. Memory of opponents is more potent than visual sign stimuli after social hierarchy has been established

    DEFF Research Database (Denmark)

    Korzan, W.J.; Höglund, Erik; Watt, M.J.

    2007-01-01

    During agonistic interactions between male Anolis carolinensis, perception of a visual sign stimulus (darkened eyespots) not only inhibits aggression and promotes initial attainment of dominant social status, but also evokes distinct neuroendocrine responses in each opponent. This study was desig......During agonistic interactions between male Anolis carolinensis, perception of a visual sign stimulus (darkened eyespots) not only inhibits aggression and promotes initial attainment of dominant social status, but also evokes distinct neuroendocrine responses in each opponent. This study...... was designed to examine the effect of eyespot manipulation on behavior and social rank during a second interaction between opponents that had previously established a natural dyadic social hierarchy. Prior to a second interaction, eyespots of familiar size-matched combatants were manipulated to reverse...... information conveyed by this visual signal. Eyespots on the previously dominant male were masked with green paint to indicate low aggression and social status. Previously subordinate males had their eyespots permanently marked with black paint to convey high aggression and status. Opponents were then re...

  19. Grid Generation Techniques Utilizing the Volume Grid Manipulator

    Science.gov (United States)

    Alter, Stephen J.

    1998-01-01

    This paper presents grid generation techniques available in the Volume Grid Manipulation (VGM) code. The VGM code is designed to manipulate existing line, surface and volume grids to improve the quality of the data. It embodies an easy to read rich language of commands that enables such alterations as topology changes, grid adaption and smoothing. Additionally, the VGM code can be used to construct simplified straight lines, splines, and conic sections which are common curves used in the generation and manipulation of points, lines, surfaces and volumes (i.e., grid data). These simple geometric curves are essential in the construction of domain discretizations for computational fluid dynamic simulations. By comparison to previously established methods of generating these curves interactively, the VGM code provides control of slope continuity and grid point-to-point stretchings as well as quick changes in the controlling parameters. The VGM code offers the capability to couple the generation of these geometries with an extensive manipulation methodology in a scripting language. The scripting language allows parametric studies of a vehicle geometry to be efficiently performed to evaluate favorable trends in the design process. As examples of the powerful capabilities of the VGM code, a wake flow field domain will be appended to an existing X33 Venturestar volume grid; negative volumes resulting from grid expansions to enable flow field capture on a simple geometry, will be corrected; and geometrical changes to a vehicle component of the X33 Venturestar will be shown.

  20. Lower subcortical gray matter volume in both younger smokers and established smokers relative to non-smokers

    Science.gov (United States)

    Hanlon, Colleen A.; Owens, Max M.; Joseph, Jane E.; Zhu, Xun; George, Mark S.; Brady, Kathleen T.; Hartwell, Karen J.

    2014-01-01

    Although established adult smokers with long histories of nicotine dependence have lower neural tissue volume than non-smokers, it is not clear if lower regional brain volume is also observed in younger, less established smokers. The primary goal of this study was to investigate neural tissue volume in a large group of smokers and non-smokers, with a secondary goal of measuring the impact of age on these effects. We used voxel-based morphometry to compare regional gray matter volume in 118 individuals (59 smokers, 59 age- and gender-matched non-smokers). Younger smokers had significantly lower gray matter volume in the left thalamus and the left amygdala than their non-smoking peers (family-wise error-corrected clusters, P smokers. Established smokers had significantly lower gray matter volume than age-matched non-smokers in the insula, parahippocampal gyrus and pallidum. Medial prefrontal cortex gray matter volume was negatively correlated with pack-years of smoking among the established smokers, but not the younger smokers. These data reveal that regional tissue volume differences are not limited exclusively to established smokers. Deficits in young adults indicate that cigarette smoking may either be deleterious to the thalamus and amygdala at an earlier age than previously reported, or that pre-existing differences in these areas may predispose individuals to the development of nicotine dependence. PMID:25125263

  1. Evaluation of conformal radiotherapy techniques through physics and biologic criteria; Avaliacao de tecnicas radioterapicas conformacionais utilizando criterios fisicos e biologicos

    Energy Technology Data Exchange (ETDEWEB)

    Bloch, Jonatas Carrero

    2012-07-01

    In the fight against cancer, different irradiation techniques have been developed based on technological advances and aiming to optimize the elimination of tumor cells with the lowest damage to healthy tissues. The radiotherapy planning goal is to establish irradiation technical parameters in order to achieve the prescribed dose distribution over the treatment volumes. While dose prescription is based on radiosensitivity of the irradiated tissues, the physical calculations on treatment planning take into account dosimetric parameters related to the radiation beam and the physical characteristics of the irradiated tissues. To incorporate tissue's radiosensitivity into radiotherapy planning calculations can help particularize treatments and establish criteria to compare and elect radiation techniques, contributing to the tumor control and the success of the treatment. Accordingly, biological models of cellular response to radiation have to be well established. This work aimed to study the applicability of using biological models in radiotherapy planning calculations to aid evaluating radiotherapy techniques. Tumor control probability (TCP) was studied for two formulations of the linear-quadratic model, with and without repopulation, as a function of planning parameters, as dose per fraction, and of radiobiological parameters, as the α/β ratio. Besides, the usage of biological criteria to compare radiotherapy techniques was tested using a prostate planning simulated with Monte Carlo code PENELOPE. Afterwards, prostate planning for five patients from the Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto, USP, using three different techniques were compared using the tumor control probability. In that order, dose matrices from the XiO treatment planning system were converted to TCP distributions and TCP-volume histograms. The studies performed allow the conclusions that radiobiological parameters can significantly influence tumor control

  2. The state-of-the Art of the Established Conventional and Advanced NDE-Techniques and Procedures for Defect Detection and Sizing - Part D: application of ultrasonic techniques for the inspection of austenitic components

    International Nuclear Information System (INIS)

    Edelmann, X.

    1997-01-01

    Ultrasonic examination of austenitic welds is possible in many cases but special techniques have often to be applied. The 'Handbook on the Ultrasonic Examination of Austenitic Welds' of the International Institute of Welding gives advice how to devise procedures for the detection, location and evaluation of ultrasonic indications of weld defects. In most circumstances it is necessary to use angled longitudinal wave probes. Austenitic weld examination is more complex and more expensive than ferritic weld examination. Detection and characterization of intergranular stress corrosion cracking has been improved by special qualification programs of the EPRI NDE Center. Dissimilar Metal welds are difficult to examine. Techniques have been developed for detection of circumferential and axial defects. Cast stainless steel structures are in general still extremely difficult to examine as a recent round robin test of the PISC program has shown. Mechanized examination with adequate data acquisition processing and presentation techniques enables better interpretation of examination results. (author)

  3. Effect of Seed Priming on Germination Properties and Seedling Establishment of Cowpea (Vigna sinensis

    Directory of Open Access Journals (Sweden)

    Hamdollah ESKANDARI

    2011-11-01

    Full Text Available Early emergence and stand establishment of cowpea are considered to be the most important yield-contributing factors in rainfed areas. Laboratory tests and afield experiment were conducted in RCB design in 2011 at a research farm in Ramhormoz, Iran, to evaluate the effects of hydropriming (8, 12 and 16 hours duration and halo priming (solutions of 1.5% KNO3 and 0.8% NaCl on seedling vigor and field establishment of cowpea. Analysis of variance of laboratory data showed that hydropriming significantly improved germination rate, seed vigor index, and seedling dry weights. However, germination percentage for seeds primed with KNO3 and non-primed seeds were statistically similar, but higher than those for NaCl priming. Overall, hydropriming treatment was comparatively superior in the laboratory tests. Invigoration of cowpea seeds by hydropriming and NaCl priming resulted in higher seedling emergence and establishment in the field, compared to control and seed priming with KNO3. Seedling emergence rate was also enhanced by priming seeds with water, suggesting that hydropriming is a simple, low cost and environmentally friendly technique for improving seed and seedling vigor of cowpea.

  4. Comparison of Parameter Identification Techniques

    Directory of Open Access Journals (Sweden)

    Eder Rafael

    2016-01-01

    Full Text Available Model-based control of mechatronic systems requires excellent knowledge about the physical behavior of each component. For several types of components of a system, e.g. mechanical or electrical ones, the dynamic behavior can be described by means of a mathematic model consisting of a set of differential equations, difference equations and/or algebraic constraint equations. The knowledge of a realistic mathematic model and its parameter values is essential to represent the behaviour of a mechatronic system. Frequently it is hard or impossible to obtain all required values of the model parameters from the producer, so an appropriate parameter estimation technique is required to compute missing parameters. A manifold of parameter identification techniques can be found in the literature, but their suitability depends on the mathematic model. Previous work dealt with the automatic assembly of mathematical models of serial and parallel robots with drives and controllers within the dynamic multibody simulation code HOTINT as fully-fledged mechatronic simulation. Several parameters of such robot models were identified successfully by our embedded algorithm. The present work proposes an improved version of the identification algorithm with higher performance. The quality of the identified parameter values and the computation effort are compared with another standard technique.

  5. Performance analysis of clustering techniques over microarray data: A case study

    Science.gov (United States)

    Dash, Rasmita; Misra, Bijan Bihari

    2018-03-01

    Handling big data is one of the major issues in the field of statistical data analysis. In such investigation cluster analysis plays a vital role to deal with the large scale data. There are many clustering techniques with different cluster analysis approach. But which approach suits a particular dataset is difficult to predict. To deal with this problem a grading approach is introduced over many clustering techniques to identify a stable technique. But the grading approach depends on the characteristic of dataset as well as on the validity indices. So a two stage grading approach is implemented. In this study the grading approach is implemented over five clustering techniques like hybrid swarm based clustering (HSC), k-means, partitioning around medoids (PAM), vector quantization (VQ) and agglomerative nesting (AGNES). The experimentation is conducted over five microarray datasets with seven validity indices. The finding of grading approach that a cluster technique is significant is also established by Nemenyi post-hoc hypothetical test.

  6. [Correlation and conversion of plasma cholinesterase activity values using three techniques].

    Science.gov (United States)

    Carmona-Fonseca, Jaime

    2007-07-01

    To determine mathematical correlations of three quantitative techniques to measure plasma cholinesterase, using reference values already established for two populations in the department of Antioquia, Colombia. In this descriptive, cross-sectional, prospective study, two independent, representative samples of working adults (18 to 65 years old) were examined. In both samples the adults worked for businesses associated with Colombia's Social Security system. Adults in the two samples had not been exposed to cholinesterase-inhibiting pesticides. The samples were from two neighboring regions of the department of Antioquia: one sample (415 adults) was from the Aburrá Valley, and the other (412 adults) was from Oriente Antioqueño (Eastern Antioquia). Plasma cholinesterase (EC 3.1.1.8) was measured using three quantitative methods: Michel, EQM, and Monotest. Linear regression equations were developed to correlate results of these three techniques. Six simple linear regression equations were defined to show the relationship of three measurement techniques for plasma cholinesterase. There was a moderate correlation of the three techniques (r = 0.686 to 0.771), but it increased (r = 0.744 to 0.811) when 12 (1.5%) outliers were eliminated. Associations among the three techniques were highly significant (P EQM (U/mL) = 0.40773 + 1.8757 (Michel [delta pH/h]); Michel (delta pH/h) = 0.25799 + 0.33871 (EQM [U/mL]); Monotest (U/L) = 462.0 + 4 565.0 (Michel [delta pH/h]); Michel (delta pH/h) = 0.42956 + 0.00012125 (Monotest [U/L]); EQM (U/mL) = 0.75333 + 0.00031056 (Monotest [U/L]); and Monotest (U/L) = 262.0 + 2 118.0 (EQM [U/mL]). The proposed mathematical models allow conversion of cholinesterase activity values using the Michel, EQM, and Monotest techniques. These models can be of assistance in Colombia and other countries where a variety of measurement techniques are used, and where it becomes difficult to compare the results of different studies. Having mathematical models

  7. Estratégia de análise da qualidade de madeira de Eucalyptus sp. para produção de celulose A laboratory technique to establish Eucalyptus sp. wood quality for kraft pulp production

    Directory of Open Access Journals (Sweden)

    José Lívio Gomide

    2004-06-01

    Full Text Available Estudou-se uma nova técnica laboratorial de análise de qualidade da madeira de Eucalyptus sp. para produção de polpa celulósica kraft. A técnica consiste em realizar, simultaneamente, quatro cozimentos de cavacos utilizando diferentes cargas de álcali ativo para estabelecer a característica de deslignificação da madeira. Pelo uso de equações de regressão, calcula-se o álcali ativo necessário para obter o número kappa desejado, o rendimento, a viscosidade e álcali consumido para o kappa objetivo. Os estudos estatísticos evidenciaram que uma única batelada de quatro cozimentos é suficiente, não sendo necessário realizar repetições.A new laboratory technique was tested to determine Eucalyptus sp. wood quality for kraft pulp production. This technique consists in performing four cooks simultaneously using different active alkali charges to establish the wood delignification characteristics. Based on regression equation it is possible to determine the alkali charge necessary to obtain a desired kappa number and the yield, viscosity and the alkali consumed for the target kappa. Statistical analysis demonstrated that a set of four cooks without replication is sufficient to determine the wood quality characteristics.

  8. Broadcast Expenses Controlling Techniques in Mobile Ad-hoc Networks: A Survey

    Directory of Open Access Journals (Sweden)

    Naeem Ahmad

    2016-07-01

    Full Text Available The blind flooding of query packets in route discovery more often characterizes the broadcast storm problem, exponentially increases energy consumption of intermediate nodes and congests the entire network. In such a congested network, the task of establishing the path between resources may become very complex and unwieldy. An extensive research work has been done in this area to improve the route discovery phase of routing protocols by reducing broadcast expenses. The purpose of this study is to provide a comparative analysis of existing broadcasting techniques for the route discovery phase, in order to bring about an efficient broadcasting technique for determining the route with minimum conveying nodes in ad-hoc networks. The study is designed to highlight the collective merits and demerits of such broadcasting techniques along with certain conclusions that would contribute to the choice of broadcasting techniques.

  9. Development of a computerized tomographic system based on the FAN-BEAM technique

    International Nuclear Information System (INIS)

    Junqueira, M.M.; Santos, C.A.C.; Borges, J.C.

    1986-01-01

    The Nuclear Instrumentation Laboratory, at COPPE/UFRJ, concentrates its researches in the development of computerized tomographic systems, looking for applications in industrial and medical non destructive analysing techniques. In this work we have projected and constructed a tomographic prototype, based on the FAN-BEAM technique for irradiating the object under analysis. An algorithm previously developed to analyse parallel beams, was modified and adapted to the FAN-BEAM geometry. (Author) [pt

  10. The use of multiple respiratory inhalers requiring different inhalation techniques has an adverse effect on COPD outcomes

    Directory of Open Access Journals (Sweden)

    Bosnic-Anticevich S

    2016-12-01

    Full Text Available Sinthia Bosnic-Anticevich,1 Henry Chrystyn,2 Richard W Costello,3,4 Myrna B Dolovich,5 Monica J Fletcher,6 Federico Lavorini,7 Roberto Rodríguez-Roisin,8 Dermot Ryan,9,10 Simon Wan Yau Ming,2 David B Price2,11 1Woolcock Institute of Medical Research, School of Medical Sciences, University of Sydney and Sydney Local Health District, Sydney, NSW, Australia; 2Observational and Pragmatic Research Institute Pte Ltd, Singapore; 3RCSI Medicine, Royal College of Surgeons, 4RCSI Education & Research Centre, Beaumont Hospital, Beaumont, Dublin, Ireland; 5Department of Medicine, Respirology, McMaster University, ON, Canada; 6Education for Health, Warwick, UK; 7Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; 8Respiratory Institute, Hospital Clinic, Universitat de Barcelona, Barcelona, Spain; 9Optimum Patient Care, Cambridge, 10Centre for Population Health Sciences, University of Edinburgh, Edinburgh, 11Academic Primary Care, University of Aberdeen, Aberdeen, UK Background: Patients with COPD may be prescribed multiple inhalers as part of their treatment regimen, which require different inhalation techniques. Previous literature has shown that the effectiveness of inhaled treatment can be adversely affected by incorrect inhaler technique. Prescribing a range of device types could worsen this problem, leading to poorer outcomes in COPD patients, but the impact is not yet known. Aims: To compare clinical outcomes of COPD patients who use devices requiring similar inhalation technique with those who use devices with mixed techniques. Methods: A matched cohort design was used, with 2 years of data from the Optimum Patient Care Research Database. Matching variables were established from a baseline year of follow-up data, and two cohorts were formed: a “similar-devices cohort” and a “mixed-devices cohort”. COPD-related events were recorded during an outcome year of follow-up. The primary outcome measure was an

  11. Remarks about the displaced spectra techniques

    International Nuclear Information System (INIS)

    Behringer, K.; Pineyro, J.

    1989-01-01

    In a recent paper a new method, called displaced spectra techniques, was presented for distinguishing between sinusoidal components and narrowband random noise contributions in otherwise random noise data. It is based on Fourier transform techniques, and uses the power spectral density (PSD) and a newly-introduced second-order displaced power spectra density (SDPSD) function. In order to distinguish between the two peak types, a validation criterion has been established. In this note, three topics are covered: a) improved numerical data for the validation criterion are given by using the refined estimation procedure of the PSD and SDPSD functions by the Welch method; b) the validation criterion requires the subtraction of the background below the peaks. A semiautomatic procedure is described; c) it was observed that peaks in the real part of the SDPSD function can be accompanied by fine structure phenomena which are unresolved in the PSD function. A few remarks are made about this problem. (author)

  12. Advances in process research by radionuclide techniques

    International Nuclear Information System (INIS)

    Merz, A.; Vogg, H.

    1978-01-01

    Modifications and transformations of materials and their technical implementation in process systems require movement of materials. Radionuclide techniques can greatly help in understanding and describing these mechanisms. The specialized measuring technique is demonstrated by three examples selected from various fields of process technology. Radioactive tracer studies performed on a rotary kiln helped, inter alia, to establish a subdivision into process zones and to pinpoint areas of dust generation. Mixing and feeding actions were studied in a twin screw extruder equipped with a special screw and mixer disk arrangement. Tracer experiments conducted in two secondary settling basins indicate the differences in the mechanisms of movement of the aqueous phase if the mean residence time and the residence time distribution may be influenced not only by hydraulic loads, but also by design variants of the overflow flumes. (orig./HP) [de

  13. Legal technique: approaches to section on types

    Directory of Open Access Journals (Sweden)

    І. Д. Шутак

    2015-11-01

    Full Text Available Legal technique is a branch of knowledge about the rules of doing legal work and creating in the process a variety of legal documents, which had previously been part of the theory of law. In modern conditions of the legal technique are isolated in a separate branch of legal science, focused on solving practical problems. The purpose of this article is to analyze the types of legal techniques, in particular, on the basis of theoretical propositions about legal technique to allocate substantial characteristics and types of legal technique. O. Malko and M. Matuzov consider legal technique as a set of rules, techniques, methods of preparation, creation, registration of legal documents, their classification and accounting for their excellence, efficient use. A similar meaning is investing in this concept Alekseev, determining that the legal technique is a set of tools and techniques used in accordance with accepted rules in the formulation and systematization of legal acts to ensure their perfection. So, legal technique – theoretical and applied legal science, which studies the regularities of rational legal practice in the creation, interpretation and implementation of law. In relation to the type of legal techniques in the literature proposed different classifications. For example, G. Muromtsev technique, which is used only in the field of law, divide on the technique of law-making (legislative technique, technique of law enforcement, interpretation, technique of judicial speech, interrogation, notarial activities. V. Kartashov shared legal technique on law making and enforcement (prorealtime, interpretive yourself and prevacidrebatezw, judicial or investigative, prosecutorial, and the like. Some authors clearly indicate that the criterion by which to distinguish types of legal techniques. So, S. Alekseev notes that legal technique is classified from the point of view of the legal nature of the act made on: a techniques of legal acts; b the

  14. A New Linearization Technique Using Multi-sinh Doublet

    Directory of Open Access Journals (Sweden)

    CEHAN, V.

    2009-06-01

    Full Text Available In this paper a new linearization technique using multi-sinh doublet, implemented with a second generation current conveyor is presented. This new linearization technique is compared with the one based on multi-tanh doublets with linearization series connected diodes on the branches. The comparative study of the two linearization techniques is carried out using both dynamic range analysis, expressed by linearity error and the THD value calculation of output current, and the noise behavior of the two analyzed doublets. For the multi-sinh linearization technique proposed in the paper a method which assures the increase of the dynamic range, keeping the transconductance value constant is presented. This is done by using two design parameters: the number of series connected diodes N, which specifies the desired linear operating range and the k emitters areas ratio of the input stage transistors, which establishes the transconductance value. In the paper is also shown that if the transconductances of the two analyzed doublets are identical, and for the same values of N and k parameters, respectively, the current consumption of the multi-sinh doublet is always smaller than for the multi-tanh doublet.

  15. International Conference on Soft Computing Techniques and Engineering Application

    CERN Document Server

    Li, Xiaolong

    2014-01-01

    The main objective of ICSCTEA 2013 is to provide a platform for researchers, engineers and academicians from all over the world to present their research results and development activities in soft computing techniques and engineering application. This conference provides opportunities for them to exchange new ideas and application experiences face to face, to establish business or research relations and to find global partners for future collaboration.

  16. Evaluation of analytical techniques to determine matals in Sodium

    International Nuclear Information System (INIS)

    Biancifiori, M.A.; Zappa, G.; Amico, A.

    1985-01-01

    The influence of some instrumental parameters on the analysis of CA, Co, Cr, Cu, Fe, K, Mg, Mn, and Ni in Sodium solutions, by means of Flame Atomic Absorption Spectroscopy (FAAS), is evaluated. The best operating parameters are established and the possibility of application of this analytical technique to the detection of the metallic impurities in Sodium is evaluated, considering the concentration values of nuclear interest

  17. TAPP - Stuttgart technique and result of a large single center series

    Directory of Open Access Journals (Sweden)

    Bittner R

    2006-01-01

    Full Text Available Laparoscopic hernioplasty is assessed as a difficult operation. Operative technique determines the frequency of complications, the time of recovery and the rate of recurrences. A proper technique is absolutely necessary to achieve results that are superior to open hernia surgery. Technique: The key points in our technique are 1 use of nondisposable instruments; 2 use of blunt trocars, consisting of expanding and non-incisive cone-shaped tips; 3 spacious and curved opening to the peritoneum, high above all possible hernia openings; 4 meticulous dissection of the entire pelvic floor; 5 complete reduction of the hernial sac; 6 wide parietalization of the peritoneal sac, at least down to the mid of psoas muscle; 7 implantation of a large mesh, at least 10 cm x 15 cm; 8 fixation of the mesh by clip to Cooper′s ligament, to the rectus muscle and lateral to the epigastric vessels, high above the ileopubic tract; 9 the use of glue allows fixation also to the latero-caudial region; and 10 closure of the peritoneum by running suture. Results: With this technique in 12,678 hernia repairs, the following results could be achieved: operating time - 40 min; morbidity - 2.9%; recurrence rate - 0.7%; disability of work - 14 days. In all types of hernias (recurrence after previous open surgery, recurrence after previous preperitoneal operation, scrotal hernia, hernia in patients after transabdominal prostate resection, similar results could be achieved. Summary: Laparoscopic hernia repair can be performed successfully in clinical practice even by surgeons in training. Precondition for the success is a strictly standardized operative technique and a well-structured educational program.

  18. Dosimetry tools and techniques for IMRT

    International Nuclear Information System (INIS)

    Low, Daniel A.; Moran, Jean M.; Dempsey, James F.; Dong Lei; Oldham, Mark

    2011-01-01

    Intensity modulated radiation therapy (IMRT) poses a number of challenges for properly measuring commissioning data and quality assurance (QA) radiation dose distributions. This report provides a comprehensive overview of how dosimeters, phantoms, and dose distribution analysis techniques should be used to support the commissioning and quality assurance requirements of an IMRT program. The proper applications of each dosimeter are described along with the limitations of each system. Point detectors, arrays, film, and electronic portal imagers are discussed with respect to their proper use, along with potential applications of 3D dosimetry. Regardless of the IMRT technique utilized, some situations require the use of multiple detectors for the acquisition of accurate commissioning data. The overall goal of this task group report is to provide a document that aids the physicist in the proper selection and use of the dosimetry tools available for IMRT QA and to provide a resource for physicists that describes dosimetry measurement techniques for purposes of IMRT commissioning and measurement-based characterization or verification of IMRT treatment plans. This report is not intended to provide a comprehensive review of commissioning and QA procedures for IMRT. Instead, this report focuses on the aspects of metrology, particularly the practical aspects of measurements that are unique to IMRT. The metrology of IMRT concerns the application of measurement instruments and their suitability, calibration, and quality control of measurements. Each of the dosimetry measurement tools has limitations that need to be considered when incorporating them into a commissioning process or a comprehensive QA program. For example, routine quality assurance procedures require the use of robust field dosimetry systems. These often exhibit limitations with respect to spatial resolution or energy response and need to themselves be commissioned against more established dosimeters. A chain of

  19. Establish an automated flow injection ESI-MS method for the screening of fragment based libraries: Application to Hsp90.

    Science.gov (United States)

    Riccardi Sirtori, Federico; Caronni, Dannica; Colombo, Maristella; Dalvit, Claudio; Paolucci, Mauro; Regazzoni, Luca; Visco, Carlo; Fogliatto, Gianpaolo

    2015-08-30

    ESI-MS is a well established technique for the study of biopolymers (nucleic acids, proteins) and their non covalent adducts, due to its capacity to detect ligand-target complexes in the gas phase and allows inference of ligand-target binding in solution. In this article we used this approach to investigate the interaction of ligands to the Heat Shock Protein 90 (Hsp90). This enzyme is a molecular chaperone involved in the folding and maturation of several proteins which has been subjected in the last years to intensive drug discovery efforts due to its key role in cancer. In particular, reference compounds, with a broad range of dissociation constants from 40pM to 100μM, were tested to assess the reliability of ESI-MS for the study of protein-ligand complexes. A good agreement was found between the values measured with a fluorescence polarization displacement assay and those determined by mass spectrometry. After this validation step we describe the setup of a medium throughput screening method, based on ESI-MS, suitable to explore interactions of therapeutic relevance biopolymers with chemical libraries. Our approach is based on an automated flow injection ESI-MS method (AFI-MS) and has been applied to screen the Nerviano Medical Sciences proprietary fragment library of about 2000 fragments against Hsp90. In order to discard false positive hits and to discriminate those of them interacting with the N-terminal ATP binding site, competition experiments were performed using a reference inhibitor. Gratifyingly, this group of hits matches with the ligands previously identified by NMR FAXS techniques and confirmed by X-ray co-crystallization experiments. These results support the use of AFI-MS for the screening of medium size libraries, including libraries of small molecules with low affinity typically used in fragment based drug discovery. AFI-MS is a valid alternative to other techniques with the additional opportunities to identify compounds interacting with

  20. Auralization of an orchestra using multichannel and multisource technique (A)

    DEFF Research Database (Denmark)

    Vigeant, Michelle C.; Wang, Lily M.; Rindel, Jens Holger

    2006-01-01

    Previous work has shown the importance of including source directivity in computer modeling for auralizations. A newer method to capture source directivity in auralizations is the multichannel technique, which uses multichannel anechoic recordings. In this study, five-channel anechoic recordings ...... made with a single channel orchestral anechoic recording using (ii) a surface source and (iii) a single omni-directional source. [Work supported by the National Science Foundation.]......Previous work has shown the importance of including source directivity in computer modeling for auralizations. A newer method to capture source directivity in auralizations is the multichannel technique, which uses multichannel anechoic recordings. In this study, five-channel anechoic recordings...... were obtained for every orchestral part of two symphonies at the Technical University of Denmark. Five-channel auralizations were then created for each instrument, located at its typical position on-stage in a concert hall, by convolving five impulse responses from sources that each represent...