WorldWideScience

Sample records for previously developed procedure

  1. Suburethral sling procedures after previous surgery for urinary ...

    African Journals Online (AJOL)

    Objective. To compare the outcome of suburethral sling procedures (tension-free vaginal tape (TVT), obturator tape (Ob-tape)) for stress urinary incontinence (SUI) in women with previous surgery for SUI or pelvic organ prolapse (POP). Methods. A comparative, descriptive, retrospective study was done using information ...

  2. Developing policies and procedures.

    Science.gov (United States)

    Randolph, Susan A

    2006-11-01

    The development of policies and procedures is an integral part of the occupational health nurse's role. Policies and procedures serve as the foundation for the occupational health service and are based on its vision, mission, culture, and values. The design and layout selected for the policies and procedures should be simple, consistent, and easy to use. The same format should be used for all existing and new policies and procedures. Policies and procedures should be reviewed periodically based on a specified time frame (i.e., annually). However, some policies may require a more frequent review if they involve rapidly changing external standards, ethical issues, or emerging exposures.

  3. Aortic pseudoaneurysm detected on external jugular venous distention following a Bentall procedure 10 years previously.

    Science.gov (United States)

    Fukunaga, Naoto; Shomura, Yu; Nasu, Michihiro; Okada, Yukikatsu

    2010-11-01

    An asymptomatic 49-year-old woman was admitted for the purpose of surgery for aortic pseudoaneurysm. She had Marfan syndrome and had undergone an emergent Bentall procedure 10 years previously. About six months previously, she could palpate distended bilateral external jugular veins, which became distended only in a supine position and without any other symptoms. Enhanced computed tomography revealed an aortic pseudoaneurysm originating from a previous distal anastomosis site. During induction of general anesthesia in a supine position, bilateral external jugular venous distention was remarkable. Immediately after a successful operation, distention completely resolved. The present case emphasizes the importance of physical examination leading to a diagnosis of asymptomatic life-threatening diseases in patients with a history of previous aortic surgery.

  4. Modified Latarjet Procedure Without Capsulolabral Repair for the Treatment of Failed Previous Operative Stabilizations in Athletes.

    Science.gov (United States)

    Ranalletta, Maximiliano; Rossi, Luciano A; Bertona, Agustin; Tanoira, Ignacio; Maignon, Gastón D; Bongiovanni, Santiago L

    2018-02-03

    To analyze time to return to sport, functional outcomes, and recurrences of the modified Latarjet procedure without capsulolabral repair in athletes with recurrent anterior shoulder instability after a failed previous operative stabilization. We included athletes with recurrent anterior shoulder instability with a previous failed operative stabilization treated with the modified Latarjet procedure without capsulolabral repair with a minimum of 2-year follow-up. Return to sports, range of motion, the Rowe score, a visual analog scale for pain in sport activity, and the Athletic Shoulder Outcome Scoring System were used to assess functional outcomes. Recurrences were also evaluated. The postoperative bone block position and consolidation were assessed with computed tomography. Between June 2008 and June 2015, 68 athletes were treated with the modified Latarjet procedure without capsulolabral reconstruction for recurrent shoulder instability after a previous failed stabilization surgery. The mean follow-up was 44 months (range, 24-108 months), and the mean age at the time of operation was 26.8 years (range, 17-35 years). All the patients returned to sports, and 95% returned to the same sport they practiced before the surgery, all to the same level. No significant difference in shoulder range of motion was found between preoperative and postoperative results. The Rowe score, visual analog scale, and Athletic Shoulder Outcome Scoring System showed statistical improvement after operation (P Latarjet without capsulolabral repair produced excellent functional outcomes with most athletes returning to sport at the same level they had before the surgery without recurrences. Level IV, therapeutic, case series study. Copyright © 2017 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

  5. Toothbrushing procedure in schoolchildren with no previous formal instruction: variables associated to dental biofilm removal.

    Science.gov (United States)

    Rossi, Glenda N; Sorazabal, Ana L; Salgado, Pablo A; Squassi, Aldo F; Klemonskis, Graciela L

    2016-04-01

    The aim of this study was to establish the association between features regarding brushing procedure performed by schoolchildren without previous formal training and the effectiveness of biofilm removal. Out of a population of 8900 6- and 7-year-old schoolchildren in Buenos Aires City, 600 children were selected from schools located in homogeneous risk areas. Informed consent was requested from parents or guardians and formal assent was obtained from children themselves. The final sample consisted of 316 subjects. The following tooth brushing variables were analyzed: toothbrush-gripping, orientation of active part of bristles with respect to the tooth, type of movement applied, brushing both jaws together or separately, including all 6 sextants and duration of brushing. The level of dental biofilm after brushing was determined by O'Leary's index, acceptable cut-off point = 20%. Four calibrated dentists performed observations and clinical examinations. Frequency distribution, central tendency and dispersion measures were calculated. Cluster analyses were performed; proportions of variables for each cluster were compared with Bonferroni's correction and OR was obtained. The most frequent categories were: palm gripping (71.51%); perpendicular orientation (85.8%); horizontal movement (95.6%); separate addressing of jaws (68%) and inclusion of all 6 sextants (50.6%). Mean duration of brushing was 48.78 ± 27.36 seconds. 42.7% of the children achieved an acceptable biofilm level. The cluster with the highest proportion of subjects with acceptable post-brushing biofilm levels (p<0.05) differed significantly from the rest for the variable "inclusion of all 6 sextants in brushing procedure". OR was 2.538 (CI 95% 1.603 - 4.017). Inclusion of all six sextants could be a determinant variable for the removal of biofilm by brushing in schoolchildren, and should be systematized as a component in oral hygiene education. Sociedad Argentina de Investigación Odontológica.

  6. Reoperative Aortic Root Replacement in Patients with Previous Aortic Root or Aortic Valve Procedures

    Directory of Open Access Journals (Sweden)

    Byung Kwon Chong

    2016-08-01

    Full Text Available Background: Generalization of standardized surgical techniques to treat aortic valve (AV and aortic root diseases has benefited large numbers of patients. As a consequence of the proliferation of patients receiving aortic root surgeries, surgeons are more frequently challenged by reoperative aortic root procedures. The aim of this study was to evaluate the outcomes of redo-aortic root replacement (ARR. Methods: We retrospectively reviewed 66 patients (36 male; mean age, 44.5±9.5 years who underwent redo-ARR following AV or aortic root procedures between April 1995 and June 2015. Results: Emergency surgeries comprised 43.9% (n=29. Indications for the redo-ARR were aneurysm (n=12, pseudoaneurysm (n=1, or dissection (n=6 of the residual native aortic sinus in 19 patients (28.8%, native AV dysfunction in 8 patients (12.1%, structural dysfunction of an implanted bioprosthetic AV in 19 patients (28.8%, and infection of previously replaced AV or proximal aortic grafts in 30 patients (45.5%. There were 3 early deaths (4.5%. During follow- up (median, 54.65 months; quartile 1–3, 17.93 to 95.71 months, there were 14 late deaths (21.2%, and 9 valve-related complications including reoperation of the aortic root in 1 patient, infective endocarditis in 3 patients, and hemorrhagic events in 5 patients. Overall survival and event-free survival rates at 5 years were 81.5%±5.1% and 76.4%±5.4%, respectively. Conclusion: Despite technical challenges and a high rate of emergency conditions in patients requiring redo-ARR, early and late outcomes were acceptable in these patients.

  7. Development of FWD procedures manual.

    Science.gov (United States)

    2010-04-01

    In this project, the state-of-practice in FWD testing and analysis procedures were examined : by looking at the standard protocols of a number of other highway agencies. The specific : needs of NJDOT were also examined and a protocol was developed th...

  8. Reoperative reimplantation procedure after previous remodeling in a patient with Marfan syndrome.

    Science.gov (United States)

    Hechadi, Jawad; De Kerchove, Laurent; Vohra, Hunaid A; El Khoury, Gebrine

    2013-05-01

    A 43-year-old man with Marfan syndrome presented with recurrent aortic root dilatation and aortic regurgitation at ten years after a remodeling (Yacoub) procedure. Herein is described a reoperative valve-sparing procedure employing the reimplantation technique (David procedure) used in the treatment of this patient.

  9. 40 CFR 80.131 - Agreed upon procedures for GTAB, certain conventional gasoline imported by truck, previously...

    Science.gov (United States)

    2010-07-01

    ..., certain conventional gasoline imported by truck, previously certified gasoline used to produce gasoline... gasoline used to produce gasoline, and butane blenders. (a) Attest procedures for GTAB. The following are... conventional gasoline and of RFG produced. Agree the volumes from the tank activity records to the batch volume...

  10. Developing Flexible Procedural Knowledge in Undergraduate Calculus

    Science.gov (United States)

    Maciejewski, Wes; Star, Jon R.

    2016-01-01

    Mathematics experts often choose appropriate procedures to produce an efficient or elegant solution to a mathematical task. This "flexible procedural knowledge" distinguishes novice and expert procedural performances. This article reports on an intervention intended to aid the development of undergraduate calculus students' flexible use…

  11. Developing, adopting and adapting operating procedures

    International Nuclear Information System (INIS)

    Rabouhams, J.

    1986-01-01

    This lecture specifies all the dispositions which have been taken by EDF Nuclear and Fossil Generation Department - according to the fact that availability and safety largely depend on the quality of the procedures and their easy handling - in order to develop, adopt and adapt the operating procedures. The following points are treated: General organization of procedures for plant operation during normal and abnormal conditions; Personnel and extend of responsibility involved into the development of procedures (research center, training center, specialized services, nuclear station, etc.); Validation of the procedures by means of full-scope simulators; Modifications of the procedures taking into account operation experience in material and human fields; Development of simulation softs in order to perform the procedures in abnormal situations; Evolution of operating technics and future skills. (orig.)

  12. Health Code Number (HCN) Development Procedure

    Energy Technology Data Exchange (ETDEWEB)

    Petrocchi, Rocky; Craig, Douglas K.; Bond, Jayne-Anne; Trott, Donna M.; Yu, Xiao-Ying

    2013-09-01

    This report provides the detailed description of health code numbers (HCNs) and the procedure of how each HCN is assigned. It contains many guidelines and rationales of HCNs. HCNs are used in the chemical mixture methodology (CMM), a method recommended by the department of energy (DOE) for assessing health effects as a result of exposures to airborne aerosols in an emergency. The procedure is a useful tool for proficient HCN code developers. Intense training and quality assurance with qualified HCN developers are required before an individual comprehends the procedure to develop HCNs for DOE.

  13. Integrated development environment for checkout procedures

    Science.gov (United States)

    Nicklaußen, Dirk

    2002-07-01

    For the efficient usage of a Checkout System in Space Projects it is mandatory to automate the execution of test procedures and to ensure the consistency of data used in the checkout environment. In this paper a Language System and the according procedure generation environment will be described, which is used in various Space Projects (Columbus System Integration, METOP Satellite Integration, ATV Test Facilities). The Language System described here was developed as part of the Columbus Ground System (CGS). Based on the experience gained in these programmes, the Language System has been continuously extended and the software tools to support the development of checkout procedures have been adapted to the user needs using state-of-the art software technologies. In this paper an overview about the Columbus Ground System (CGS) with the Mission Database (MDB) and the Test Execution Software (TES) is given. Thereafter the Language Systems for the generation of checkout procedures are shortly introduced and the main features are presented. Particular emphasis is put on the latest development, the Integrated Development Environment (IDE) and the associated benefits for the integration process. A key element of the IDE is the integration with the Mission Database including a flexible configuration management system.

  14. Development of symptoms-oriented operating procedures

    International Nuclear Information System (INIS)

    Colquhoun, R.

    1984-01-01

    Until recently, the formal treatment of control room procedures for upset conditions in nuclear power plants has been event-oriented. This orientation was not so much a reflection of power plant operating practice as it was a reflection of design-oriented thinking - design-basis events, therefore event-oriented procedures. Event orientation is not common in other professions. In the medical profession, for example, the stabilization of vital functions through a symptoms-oriented approach has priority over diagnosis and prognosis. The American nuclear power industry has initiated programs for the development and application of a symptoms-oriented approach for handling upset conditions. Canadian programs have independently paralleled the US programs. This article describes the rationale and current applications of the Canadian programs and identifies the relevance of a generic symptoms-based emergency procedure to current operating practices

  15. Predictive factors for the development of diabetes in women with previous gestational diabetes mellitus

    DEFF Research Database (Denmark)

    Damm, P.; Kühl, C.; Bertelsen, Aksel

    1992-01-01

    OBJECTIVES: The purpose of this study was to determine the incidence of diabetes in women with previous dietary-treated gestational diabetes mellitus and to identify predictive factors for development of diabetes. STUDY DESIGN: Two to 11 years post partum, glucose tolerance was investigated in 241...... women with previous dietary-treated gestational diabetes mellitus and 57 women without previous gestational diabetes mellitus (control group). RESULTS: Diabetes developed in 42 (17.4%) women with previous gestational diabetes mellitus (3.7% insulin-dependent diabetes mellitus and 13.7% non......-insulin-dependent diabetes mellitus). Diabetes did not develop in any of the controls. Predictive factors for diabetes development were fasting glucose level at diagnosis (high glucose, high risk), preterm delivery, and an oral glucose tolerance test result that showed diabetes 2 months post partum. In a subgroup...

  16. Impact assessment procedures for sustainable development: A complexity theory perspective

    International Nuclear Information System (INIS)

    Nooteboom, Sibout

    2007-01-01

    The author assumes that effective Impact Assessment procedures should somehow contribute to sustainable development. There is no widely agreed framework for evaluating such effectiveness. The author suggests that complexity theories may offer criteria. The relevant question is 'do Impact Assessment Procedures contribute to the 'requisite variety' of a social system for it to deal with changing circumstances?' Requisite variety theoretically relates to the capability of a system to deal with changes in its environment. The author reconstructs how thinking about achieving sustainable development has developed in a sequence of discourses in The Netherlands since the 1970s. Each new discourse built on the previous ones, and is supposed to have added to 'requisite variety'. The author asserts that Impact Assessment procedures may be a necessary component in such sequences and derives possible criteria for effectiveness

  17. Development of preventive maintenance procedures and schedules

    International Nuclear Information System (INIS)

    Schlenker, H.V.; Hammel, J.

    1977-01-01

    An outline of the procedures and schedules developed for preventive maintenance in power stations within the Rheinisch-Westfaelisches Elektrizitaetswerk (RWE) is presented. After an introduction of maintenance in general the different kinds of preventive maintenance activities are described. This includes also the prerequisite identification systems. The aims of preventive maintenance and the measures are explained that have to be taken, if these aims are to be achieved. A number of examples from actual practice are cited. (orig.) [de

  18. The Case for Laboratory Developed Procedures

    Science.gov (United States)

    Sabatini, Linda M.; Tsongalis, Gregory J.; Caliendo, Angela M.; Olsen, Randall J.; Ashwood, Edward R.; Bale, Sherri; Benirschke, Robert; Carlow, Dean; Funke, Birgit H.; Grody, Wayne W.; Hayden, Randall T.; Hegde, Madhuri; Lyon, Elaine; Pessin, Melissa; Press, Richard D.; Thomson, Richard B.

    2017-01-01

    An explosion of knowledge and technology is revolutionizing medicine and patient care. Novel testing must be brought to the clinic with safety and accuracy, but also in a timely and cost-effective manner, so that patients can benefit and laboratories can offer testing consistent with current guidelines. Under the oversight provided by the Clinical Laboratory Improvement Amendments, laboratories have been able to develop and optimize laboratory procedures for use in-house. Quality improvement programs, interlaboratory comparisons, and the ability of laboratories to adjust assays as needed to improve results, utilize new sample types, or incorporate new mutations, information, or technologies are positive aspects of Clinical Laboratory Improvement Amendments oversight of laboratory-developed procedures. Laboratories have a long history of successful service to patients operating under Clinical Laboratory Improvement Amendments. A series of detailed clinical examples illustrating the quality and positive impact of laboratory-developed procedures on patient care is provided. These examples also demonstrate how Clinical Laboratory Improvement Amendments oversight ensures accurate, reliable, and reproducible testing in clinical laboratories. PMID:28815200

  19. The Case for Laboratory Developed Procedures

    Directory of Open Access Journals (Sweden)

    Karen L. Kaul MD, PhD

    2017-07-01

    Full Text Available An explosion of knowledge and technology is revolutionizing medicine and patient care. Novel testing must be brought to the clinic with safety and accuracy, but also in a timely and cost-effective manner, so that patients can benefit and laboratories can offer testing consistent with current guidelines. Under the oversight provided by the Clinical Laboratory Improvement Amendments, laboratories have been able to develop and optimize laboratory procedures for use in-house. Quality improvement programs, interlaboratory comparisons, and the ability of laboratories to adjust assays as needed to improve results, utilize new sample types, or incorporate new mutations, information, or technologies are positive aspects of Clinical Laboratory Improvement Amendments oversight of laboratory-developed procedures. Laboratories have a long history of successful service to patients operating under Clinical Laboratory Improvement Amendments. A series of detailed clinical examples illustrating the quality and positive impact of laboratory-developed procedures on patient care is provided. These examples also demonstrate how Clinical Laboratory Improvement Amendments oversight ensures accurate, reliable, and reproducible testing in clinical laboratories.

  20. 78 FR 35263 - Freeport LNG Development, L.P.; Application for Blanket Authorization To Export Previously...

    Science.gov (United States)

    2013-06-12

    ... the LNG at the time of export. The Application was filed under section 3 of the Natural Gas Act (NGA... not prohibited by U.S. law or policy. Current Application The current Application is filed in... Freeport LNG Development, L.P.; Application for Blanket Authorization To Export Previously Imported...

  1. Developing Reading Comprehension through Metacognitive Strategies: A Review of Previous Studies

    Science.gov (United States)

    Channa, Mansoor Ahmed; Nordin, Zaimuariffudin Shukri; Siming, Insaf Ali; Chandio, Ali Asgher; Koondher, Mansoor Ali

    2015-01-01

    This paper has reviewed the previous studies on metacognitive strategies based on planning, monitoring, and evaluating in order to develop reading comprehension. The main purpose of this review in metacognition, and reading domain is to help readers to enhance their capabilities and power reading through these strategies. The researchers reviewed…

  2. Procedure Integrated Development Environment (PRIDE), Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA captures and distributes operational knowledge in the form of procedures. These procedures are created and accessed by a range of people performing many...

  3. Procedure Integrated Development Environment (PRIDE), Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA captures and distributes operational knowledge in the form of procedures. These procedures are created and accessed by a range of people performing many...

  4. Development of PSA procedure for a criticality in reprocessing facilities

    International Nuclear Information System (INIS)

    Endo, Shigeki; Takanashi, Mitsuhiro; Ueda, Yoshinori

    2012-08-01

    Utilization of risk information for the nuclear safety regulation is being discussed in Japan. The development of probabilistic safety assessment (PSA) procedure is indispensable for the utilization of risk information. The Japan Nuclear Energy Safety Organization (JNES) has been conducting trial PSA to a model plant for major events, i.e. hydrogen explosion, solution boiling, rapid decomposition of TBP complexes, criticality, solvent fire, leakage of molten glass, leakage of high active concentrated liquid waste, loss of all AC electricity, drop of a fuel assembly, for the purpose of developing the PSA procedure for reprocessing facilities. For criticality events results of trial PSA were summarized as a report in which how to evaluate an amount of radioactive materials released from a facility and a health effect on the public were emphasized. Therefore, for criticality events the results of trial PSA were summarized in this report to emphasize procedures from making event progression scenarios to quantifying event sequences, which were not handled in the previous report, in a style of a document describing PSA procedures. (author)

  5. Mentoring to develop research selfefficacy, with particular reference to previously disadvantaged individuals

    OpenAIRE

    S. Schulze

    2010-01-01

    The development of inexperienced researchers is crucial. In response to the lack of research self-efficacy of many previously disadvantaged individuals, the article examines how mentoring can enhance the research self-efficacy of mentees. The study is grounded in the self-efficacy theory (SET) – an aspect of the social cognitive theory (SCT). Insights were gained from an in-depth study of SCT, SET and mentoring, and from a completed mentoring project. This led to the formulation of three basi...

  6. Antimicrobial Testing Methods & Procedures Developed by EPA's Microbiology Laboratory

    Science.gov (United States)

    We develop antimicrobial testing methods and standard operating procedures to measure the effectiveness of hard surface disinfectants against a variety of microorganisms. Find methods and procedures for antimicrobial testing.

  7. Mentoring to develop research selfefficacy, with particular reference to previously disadvantaged individuals

    Directory of Open Access Journals (Sweden)

    S. Schulze

    2010-07-01

    Full Text Available The development of inexperienced researchers is crucial. In response to the lack of research self-efficacy of many previously disadvantaged individuals, the article examines how mentoring can enhance the research self-efficacy of mentees. The study is grounded in the self-efficacy theory (SET – an aspect of the social cognitive theory (SCT. Insights were gained from an in-depth study of SCT, SET and mentoring, and from a completed mentoring project. This led to the formulation of three basic principles. Firstly, institutions need to provide supportive environmental conditions that facilitate research selfefficacy. This implies a supportive and efficient collective system. The possible effects of performance ratings and reward systems at the institution also need to be considered. Secondly, mentoring needs to create opportunities for young researchers to experience successful learning as a result of appropriate action. To this end, mentees need to be involved in actual research projects in small groups. At the same time the mentor needs to facilitate skills development by coaching and encouragement. Thirdly, mentors need to encourage mentees to believe in their ability to successfully complete research projects. This implies encouraging positive emotional states, stimulating self-reflection and self-comparison with others in the group, giving positive evaluative feedback and being an intentional role model.

  8. Development of quality assurance procedures for research and development

    Energy Technology Data Exchange (ETDEWEB)

    Nam, Ji Hee

    2000-12-01

    The complexity and the diversity of R and D project are increasing and the life cycle in science and technology is getting shorter. It is required that the results of research and development are subject to prove their objectivity. KAERI is performing complex and various R and D projects. It is necessary that the principle of R and D QA should be applicated to projects for the efficient conduct of R and D and the objective and fair evaluation of the results. So, such requirements as are commonly applicable and necessary, regardless of the type of project and the degree of risk, are selected and QA procedures are established therewith.

  9. Development of quality assurance procedures for research and development

    International Nuclear Information System (INIS)

    Nam, Ji Hee

    2000-12-01

    The complexity and the diversity of R and D project are increasing and the life cycle in science and technology is getting shorter. It is required that the results of research and development are subject to prove their objectivity. KAERI is performing complex and various R and D projects. It is necessary that the principle of R and D QA should be applicated to projects for the efficient conduct of R and D and the objective and fair evaluation of the results. So, such requirements as are commonly applicable and necessary, regardless of the type of project and the degree of risk, are selected and QA procedures are established therewith

  10. Rate of torque and electromyographic development during anticipated eccentric contraction is lower in previously strained hamstrings.

    Science.gov (United States)

    Opar, David A; Williams, Morgan D; Timmins, Ryan G; Dear, Nuala M; Shield, Anthony J

    2013-01-01

    The effect of prior strain injury on myoelectrical activity of the hamstrings during tasks requiring high rates of torque development has received little attention. To determine if recreational athletes with a history of unilateral hamstring strain injury will exhibit lower levels of myoelectrical activity during eccentric contraction, rate of torque development (RTD), and impulse (IMP) at 30, 50, and 100 milliseconds after the onset of myoelectrical activity or torque development in the previously injured limb compared with the uninjured limb. Case control study; Level of evidence, 3. Twenty-six recreational athletes were recruited. Of these, 13 athletes had a history of unilateral hamstring strain injury (all confined to biceps femoris long head), and 13 had no history of hamstring strain injury. Following familiarization, all athletes undertook isokinetic dynamometry testing and surface electromyography (integrated EMG; iEMG) assessment of the biceps femoris long head and medial hamstrings during eccentric contractions at -60 and -180 deg·s(-1). In the injured limb of the injured group, compared with the contralateral uninjured limb, RTD and IMP was lower during -60 deg·s(-1) eccentric contractions at 50 milliseconds (RTD: injured limb, 312.27 ± 191.78 N·m·s(-1) vs uninjured limb, 518.54 ± 172.81 N·m·s(-1), P = .008; IMP: injured limb, 0.73 ± 0.30 N·m·s vs uninjured limb, 0.97 ± 0.23 N·m·s, P = .005) and 100 milliseconds (RTD: injured limb, 280.03 ± 131.42 N·m·s(-1) vs uninjured limb, 460.54 ± 152.94 N·m·s(-1), P = .001; IMP: injured limb, 2.15 ± 0.89 N·m·s vs uninjured limb, 3.07 ± 0.63 N·m·s, P contraction. Biceps femoris long head muscle activation was lower at 100 milliseconds at both contraction speeds (-60 deg·s(-1), normalized iEMG activity [×1000]: injured limb, 26.25 ± 10.11 vs uninjured limb, 33.57 ± 8.29, P = .009; -180 deg·s(-1), normalized iEMG activity [×1000]: injured limb, 31.16 ± 10.01 vs uninjured limb, 39.64

  11. The feasibility and safety of single-incision totally extraperitoneal inguinal hernia repair after previous lower abdominal surgery: 350 procedures at a single center.

    Science.gov (United States)

    Wakasugi, Masaki; Suzuki, Yozo; Tei, Mitsuyoshi; Anno, Kana; Mikami, Tsubasa; Tsukada, Ryo; Koh, Masahiro; Furukawa, Kenta; Masuzawa, Toru; Kishi, Kentaro; Tanemura, Masahiro; Akamatsu, Hiroki

    2017-03-01

    To evaluate the feasibility and safety of single-incision laparoscopic surgery for totally extraperitoneal inguinal hernia repair (SILS-TEP) with previous lower abdominal surgery (PLAS). A retrospective analysis of 350 patients undergoing SILS-TEP for a primary inguinal hernia from January 2012 to December 2015 at Osaka Police Hospital was performed, and the outcomes of the patients with and without PLAS were compared. SILS-TEP was performed in 84 patients with PLAS and 266 patients without PLAS. Appendectomy was the most common previous operative procedure. There were more patients with an ASA score of ≥3 in the PLAS group than in the control group (p < 0.05). The mean operative time, and the rates of conversion and postoperative complications were comparable between the two groups. There were no cases of recurrence in either group. SILS-TEP could be safely performed in patients with PLAS and achieved better cosmetic outcomes than conventional laparoscopic surgery.

  12. Effect of previous exhaustive exercise on metabolism and fatigue development during intense exercise in humans

    DEFF Research Database (Denmark)

    Iaia, F. M.; Perez-Gomez, J.; Nordsborg, Nikolai

    2010-01-01

    The present study examined how metabolic response and work capacity are affected by previous exhaustive exercise. Seven subjects performed an exhaustive cycle exercise ( approximately 130%-max; EX2) after warm-up (CON) and 2 min after an exhaustive bout at a very high (VH; approximately 30 s), high...... during a repeated high-intensity exercise lasting 1/2-2 min....

  13. Development and validation of the PROcedural Sedation Assessment Survey (PROSAS) for assessment of procedural sedation quality.

    Science.gov (United States)

    Leffler, Daniel A; Bukoye, Bolanle; Sawhney, Mandeep; Berzin, Tyler; Sands, Kenneth; Chowdary, Sona; Shah, Anita; Barnett, Sheila

    2015-01-01

    More than 20 million invasive procedures are performed annually in the United States. The vast majority are performed with moderate sedation or deep sedation, yet there is limited understanding of the drivers of sedation quality and patient satisfaction. Currently, the major gap in quality assurance for invasive procedures is the lack of procedural sedation quality measures. To develop and validate a robust, patient-centered measure of procedural sedation quality, the PROcedural Sedation Assessment Survey (PROSAS). Through a series of interviews with patients, proceduralists, nurses, anesthesiologists, and an interactive patient focus group, major domains influencing procedural sedation quality were used to create a multipart survey. The pilot survey was administered and revised in sequential cohorts of adults receiving moderate sedation for GI endoscopy. After revision, the PROSAS was administered to a validation cohort. GI endoscopy unit. A expert panel of proceduralists, nurses, and anesthesiologists, an initial survey development cohort of 40 patients, and a validation cohort of 858 patients undergoing sedation for outpatient GI endoscopy with additional surveys completed by the gastroenterologist, procedure nurse, and recovery nurse. Survey characteristics of the PROSAS. Patients were able to independently complete the PROSAS after procedural sedation before discharge. Of the patients, 91.6% reported minimal discomfort; however, 8.4% of patients reported significant discomfort and 2.4% of patients experienced hemodynamic and/or respiratory instability. There was a high correlation between patient-reported intraprocedure discomfort and both clinician assessments of procedural discomfort and patient recall of procedural pain 24 to 48 hours post procedure (P procedural sedation quality. The PROSAS may be useful in both research and clinical settings. Copyright © 2015 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.

  14. Development of Impact Aggregation Procedure for Sustainable Transport System

    OpenAIRE

    Patļins, A; Kuņicina, N

    2009-01-01

    In the investigation, the problems of utility evaluation methodology application for transport development projects evaluation are described. The main steps of development of impact aggregation procedure for sustainable transport system are described in the article. The new 3 stage environmental impact aggregation procedure is suggested.

  15. Developments in radioimmunoassay and related procedures

    International Nuclear Information System (INIS)

    1992-01-01

    The Symposium was organized in tight sessions dealing with methodological developments (two sessions), reagent production, tumour markers, clinical applications, data processing and quality control, nuclear versus non-nuclear assay methods, miscellaneous topics. The individual papers have been indexed separately for inclusion. Refs, figs and tabs

  16. Tendencies of the development of the Lithuanian criminal procedure law

    OpenAIRE

    Ažubalytė, Rima

    2010-01-01

    The tendencies of the development of the Lithuanian criminal procedure within the recent twenty years, after Lithuania has regained its independence, are analyzed in the present article. The main factors which influence lawmaking in the sphere of criminal procedure as well as in the application of the criminal procedure norms are discussed. The constitutional imperatives and the human rights, fixed in international and the European Union agreements as the main factors determining the evolutio...

  17. Synchronous development of breast cancer and chest wall fibrosarcoma after previous mantle radiation for Hodgkin's disease

    International Nuclear Information System (INIS)

    Patlas, Michael; McCready, David; Kulkarni, Supriya; Dill-Macky, Marcus J.

    2005-01-01

    Survivors of Hodgkin's disease are at increased risk of developing a second malignant neoplasm, including breast carcinoma and sarcoma. We report the first case of synchronous development of chest wall fibrosarcoma and breast carcinoma after mantle radiotherapy for Hodgkin's disease. Mammographic, sonographic and MR features are demonstrated. (orig.)

  18. Developments in UK defect assessment procedures R6 revision 4 and BS7910

    International Nuclear Information System (INIS)

    Sharples, J.K.; Ainsworth, R.A.; Budden, P.J.

    2003-01-01

    The R6 defect assessment procedures have been developed over many years by the UK nuclear power generation industry. The procedures are updated on a regular basis, taking into account the information resulting from the R6 development programme and other available information worldwide. A major revision, Revision 4, of the R6 procedures was released in 2000. Just prior to that release, in 1999, the British Standards flaw assessment procedure BS7910 was issued and combined and updated the previous published documents PD6493 and PD6539, for components operating at temperatures where creep was negligible and important, respectively. BS79l0 is also under constant development. This paper provides a brief overview of the BS7910 and R6 Revision 4 procedures and describes updates to the respective documents since they were first issued. Some ongoing developments which will lead to future revisions to the documents are also described. (author)

  19. Sustainable development, tourism and territory. Previous elements towards a systemic approach

    Directory of Open Access Journals (Sweden)

    Pierre TORRENTE

    2009-01-01

    Full Text Available Today, tourism is one of the major challenges for many countries and territories. The balance of payments, an ever-increasing number of visitors and the significant development of the tourism offer clearly illustrate the booming trend in this sector. This macro-economic approach is often used by the organizations in charge of tourism, WTO for instance. Quantitative assessments which consider the satisfaction of customers’ needs as an end in itself have prevailed both in tourism development schemes and in prospective approaches since the sixties.

  20. Automated development, control, and maintenance of plant procedures

    International Nuclear Information System (INIS)

    Gilbert, L.A.

    1990-01-01

    Plants create and track thousands of documents and written procedures every year. Increasing regulations and document requirements demand more and more resources. Not only must the procedures that are written be detailed and technically accurate, they must be controlled and revised to keep pace with changing regulations, procedure requirements and equipment. The basis of this paper is the introduction of a network-based automated approach to developing, tracking, controlling, storing, and revising procedures. This network-based product, referred to herein as PRONET, combines the best of work processing, relational data base management, graphics, and project managements software to provide the capabilities needed to effectively and efficiently automate the development, control, and maintenance of plant procedures

  1. Research on Operating Procedure Development in View of RCM Theory

    International Nuclear Information System (INIS)

    Shi, J.

    2015-01-01

    The operation of NPPs (nuclear power plants) is closely related to SSCs (Structure, System and Component) function implementations and failure recoveries, and strictly follows operating procedure. The philosophy of RCM (Reliability Centered Maintenance) which is a widely-used systematic engineering approach in industry focusing on likewise facility functions and effectiveness of maintenance is accepted in relative analysis of NPPs operation in this paper. Based on the theory of RCM, the paper will discuss general logic of operating procedure development and framework optimization as well combining NPPs engineering design. Since the quality of operating procedures has a significant impact on the safe and reliable operation of NPPs, the paper provides a proposed operating procedure development logic diagramme for reference for the procedure optimization task ahead. (author)

  2. Computer-Based Procedures for Field Workers in Nuclear Power Plants: Development of a Model of Procedure Usage and Identification of Requirements

    Energy Technology Data Exchange (ETDEWEB)

    Katya Le Blanc; Johanna Oxstrand

    2012-04-01

    The nuclear industry is constantly trying to find ways to decrease the human error rate, especially the human errors associated with procedure use. As a step toward the goal of improving procedure use performance, researchers, together with the nuclear industry, have been looking at replacing the current paper-based procedures with computer-based procedure systems. The concept of computer-based procedures is not new by any means; however most research has focused on procedures used in the main control room. Procedures reviewed in these efforts are mainly emergency operating procedures and normal operating procedures. Based on lessons learned for these previous efforts we are now exploring a more unknown application for computer based procedures - field procedures, i.e. procedures used by nuclear equipment operators and maintenance technicians. The Idaho National Laboratory and participants from the U.S. commercial nuclear industry are collaborating in an applied research effort with the objective of developing requirements and specifications for a computer-based procedure system to be used by field workers. The goal is to identify the types of human errors that can be mitigated by using computer-based procedures and how to best design the computer-based procedures to do so. This paper describes the development of a Model of Procedure Use and the qualitative study on which the model is based. The study was conducted in collaboration with four nuclear utilities and five research institutes. During the qualitative study and the model development requirements and for computer-based procedures were identified.

  3. Development of unauthorized airborne emission source identification procedure

    Science.gov (United States)

    Shtripling, L. O.; Bazhenov, V. V.; Varakina, N. S.; Kupriyanova, N. P.

    2018-01-01

    The paper presents the procedure for searching sources of unauthorized airborne emissions. To make reasonable regulation decisions on airborne pollutant emissions and to ensure the environmental safety of population, the procedure provides for the determination of a pollutant mass emission value from the source being the cause of high pollution level and the search of a previously unrecognized contamination source in a specified area. To determine the true value of mass emission from the source, the minimum of the mean-root-square mismatch criterion between the computed and measured pollutant concentration in the given location is used.

  4. Standard Review Plan Update and Development Program. Implementing Procedures Document

    Energy Technology Data Exchange (ETDEWEB)

    1992-05-01

    This implementing procedures document (IPD) was prepared for use in implementing tasks under the standard review plan update and development program (SRP-UDP). The IPD provides comprehensive guidance and detailed procedures for SRP-UDP tasks. The IPD is mandatory for contractors performing work for the SRP-UDP. It is guidance for the staff. At the completion of the SRP-UDP, the IPD will be revised (to remove the UDP aspects) and will replace NRR Office Letter No. 800 as long-term maintenance procedures.

  5. Development of computerized procedures system for nuclear power plants

    International Nuclear Information System (INIS)

    Liu Fei; Zhang Zhijian; Peng Minjun

    2007-01-01

    In order to improve the application of operating procedures, an computerized procedures presentation system (CPS) for normal operation is developed on embedded real-time operation system VxWorks using C language. This paper introduces the composing of CPS, and the design of human-machine interface are stressed. The validation of CPS is described with the example of cold startup. The system helps operators to enhance the veracity of operation and the work load of operators will be reduced. (authors)

  6. Product assurance policies and procedures for flight dynamics software development

    Science.gov (United States)

    Perry, Sandra; Jordan, Leon; Decker, William; Page, Gerald; Mcgarry, Frank E.; Valett, Jon

    1987-01-01

    The product assurance policies and procedures necessary to support flight dynamics software development projects for Goddard Space Flight Center are presented. The quality assurance and configuration management methods and tools for each phase of the software development life cycles are described, from requirements analysis through acceptance testing; maintenance and operation are not addressed.

  7. Procedural memory and speed of grammatical processing: Comparison between typically developing children and language impaired children.

    Science.gov (United States)

    Clark, Gillian M; Lum, Jarrad A G

    2017-12-01

    Procedural memory has been proposed to underlie the acquisition of a range of skills including grammar, reading, and motor skills. In developmental language disorder (DLD) it has been suggested that procedural memory problems lead to the difficulties with grammar in this group. This study aimed to extend previous research by exploring associations between procedural memory and a range of cognitive skills, in children with and without language impairments. Twenty children with DLD and 20 age-matched non-language impaired children undertook tasks assessing procedural memory, grammatical processing speed, single word and nonword reading, and motor skills (as indexed by a pegboard task). For the DLD group, no significant correlations between procedural memory and any of the variables were observed. The typically developing group showed a significant correlation (r=.482, pprocedural memory and grammatical processing speed. Correlations between procedural memory and the remaining variables were all non-significant for this group. This study provides new evidence showing that grammatical processing speed is correlated with procedural memory in typically developing children. Furthermore, results suggest that the relationship with procedural memory does not extend to reading or the types of motor skills used on a pegboard task. For the DLD group the pattern of result indicate grammatical processing, reading, and motor sequencing are not supported by procedural memory or a common memory system. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. NICU procedures are getting sweeter: development of a sucrose protocol for neonatal procedural pain.

    Science.gov (United States)

    Mokhnach, Larisa; Anderson, Marilyn; Glorioso, Rachelle; Loeffler, Katie; Shinabarger, Kelly; Thorngate, Lauren; Yates, Marna; Diercks, Kristi; Berkan, Maureen; Hou, Shwu-Shin; Millar, April; Thomas, Karen A; Walker, Wendy; Zbirun, Ilona

    2010-01-01

    Neonates in the neonatal intensive care nursery experience multiple, painful, tissue-damaging procedures daily. Pain among neonates is often underestimated and untreated, producing untoward consequences. A literature review established strong evidence supporting the use of sucrose as an analgesic for minor procedural pain among neonates. A review of unit practices and nurses' experiential evidence initiated the production of a standardized protocol in our unit at the University of Washington Medical Center NICU in Seattle.Nursing practices surrounding sucrose use differed widely in dose, timing, and patient application. We carefully evaluated evidence documenting the effectiveness as well as the safety of sucrose administration and wrote a protocol and practice standards for our primarily premature patient population. This article describes the development and execution of a standardized, nurse-implemented, sucrose protocol to reduce procedural pain.

  9. The development of simple field based procedures for extraction of ...

    African Journals Online (AJOL)

    Field and laboratory experiments were conducted to develop procedures for extracting volatiles from the vine of Adenia cissampeloides which could effect the highest yield at the lowest extraction costs and also could be produced at the cottage industry level. The participatory rural appraisal technique was used to ensure ...

  10. European wind turbine procedure development blade test methods and techniques

    Energy Technology Data Exchange (ETDEWEB)

    Bulder, B.H.; Dam, J.J.D. van; Delft, D.R.V. van [and others

    1999-03-01

    In this paper the preliminary results obtained by performing the second task of the `European Wind Turbine Testing Procedure Development` project are presented. This project is performed within and with financial support of the Standards, Measurements and Testing programme of the European Commission. (au)

  11. Developing procedures for the handling of highly radioactive materials

    International Nuclear Information System (INIS)

    Wagner, M.L.

    1994-01-01

    Handling procedures for highly radioactive materials must be analyzed for the reduction of radiation dose. In keeping with ALARA principles, time, distance, and shielding must be used to maximum benefit during the job. After an initial risk assessment is accomplished, job pre-planning meetings and cold open-quotes walk-throughsclose quotes are held in order to engineer the best workable procedure given allocated resources, and to reduce personnel exposure. This paper shows the relationship between each step in the job development, over a number of actual jobs, drawing out how subtle changes in practice can affect the individual and team radiation dose

  12. European wind turbine testing procedure developments. Task 2: Power quality

    DEFF Research Database (Denmark)

    Sørensen, Poul Ejnar; Friis Pedersen, Troels; Gerdes, G.

    2001-01-01

    quality measuremnet procedure in the Measnet cooperation of European test stations for wind turbines. The first working item of the project has been toverify the state of the art of the measurement procedures by analyses and comparisons of the measurements and data processing software of the participating......The present report describes the work done in the power quality subtask of the European Wind Turbine Testing Procedure Developments project funded by the EU SMT program. The objective of the power quality subtask has been to make recommendations andprovide background for new standards...... for measurement and testing of wind turbine power quality. The focus in the work has been to support the ongoing standardisation work in IEC with a new standard IEC61400-21 for measurement and assessment of powerquality characteristics of grid connected wind turbines. The work has also been based on the power...

  13. Development of procedure for emergency response in the combined disaster

    International Nuclear Information System (INIS)

    2013-01-01

    Lessons learned from operating experience at the emergency after a East Japan Great Earthquake, have shown that development of decision making procedure and criteria for protective action implementation would be important at the emergency in the combined disaster such as nuclear accidents caused by natural disasters (including tsunami, flood, heavy snow, fire, etc.). In this study, the problemdefinition, the concept of operation and the data development were planned for three years since fiscal year 2011. In tins year, trial calculation of evacuation time estimate (ETE) for the wide area was performed. Moreover, the basic concept and procedure for carrying out ETE condidering the combined emergency were developed based on the last year results. (author)

  14. A case of laparoscopic surgery for endometrial cancer in a patient previously treated with a transvaginal mesh procedure for pelvic organ prolapse

    Directory of Open Access Journals (Sweden)

    Kiyoshi Yoshino

    2017-11-01

    Full Text Available Transvaginal mesh (TVM surgery is an effective treatment option for women with pelvic organ prolapse (POP. Because the TVM procedure preserves the uterus, it is possible for endometrial cancer to occur at a later date. We herein present the first report of such an endometrial cancer, diagnosed well after TVM surgery for POP, and the use of laparoscopic surgery to conduct a simple total hysterectomy to treat it. Keywords: endometrial cancer, laparoscopic surgery, pelvic organ prolapse, transvaginal mesh

  15. Symptom-based emergency operating procedures development for Ignalina NPP

    International Nuclear Information System (INIS)

    Kruglov, Y.

    1999-01-01

    In this paper and lecture are presented: (1) Introduction; (2) EOP project work stages and documentation; (3) Selection and justification of accident management strategy; (4) Content of EOP package; (5) Development of EOP package; (6) EOP package verification; (7) EOP package validation; (8) EOP training; (9) EOP implementation; (10) Conditions of symptom-based emergency operating producers package application and its interconnection with event-based emergency operating procedures; (11) Rules of EOP application; EOP maintenance

  16. Development and Applications of a Stage Stacking Procedure

    Science.gov (United States)

    Kulkarni, Sameer; Celestina, Mark L.; Adamczyk, John J.

    2012-01-01

    The preliminary design of multistage axial compressors in gas turbine engines is typically accomplished with mean-line methods. These methods, which rely on empirical correlations, estimate compressor performance well near the design point, but may become less reliable off-design. For land-based applications of gas turbine engines, off-design performance estimates are becoming increasingly important, as turbine plant operators desire peaking or load-following capabilities and hot-day operability. The current work develops a one-dimensional stage stacking procedure, including a newly defined blockage term, which is used to estimate the off-design performance and operability range of a 13-stage axial compressor used in a power generating gas turbine engine. The new blockage term is defined to give mathematical closure on static pressure, and values of blockage are shown to collapse to curves as a function of stage inlet flow coefficient and corrected shaft speed. In addition to these blockage curves, the stage stacking procedure utilizes stage characteristics of ideal work coefficient and adiabatic efficiency. These curves are constructed using flow information extracted from computational fluid dynamics (CFD) simulations of groups of stages within the compressor. Performance estimates resulting from the stage stacking procedure are shown to match the results of CFD simulations of the entire compressor to within 1.6% in overall total pressure ratio and within 0.3 points in overall adiabatic efficiency. Utility of the stage stacking procedure is demonstrated by estimation of the minimum corrected speed which allows stable operation of the compressor. Further utility of the stage stacking procedure is demonstrated with a bleed sensitivity study, which estimates a bleed schedule to expand the compressors operating range.

  17. Safe procedure development to manage hazardous drugs in the workplace

    Directory of Open Access Journals (Sweden)

    Marisa Gaspar Carreño

    2017-03-01

    Full Text Available Objective: To develop a safety working procedure for the employees in the Intermutual Hospital de Levante (HIL in those areas of activity that deal with the handling of hazardous drugs (MP. Methods: The procedure was developed in six phases: 1 hazard definition; 2 definition and identification of processes and development of general correct work practices about hazardous drugs’ selection and special handling; 3 detection, selection and set of specific recommendations to handle with hazardous drugs during the processes of preparation and administration included in the hospital GFT; 4 categorization of risk during the preparation/administration and development of an identification system; 5 information and training of professionals; 6 implementation of the identification measures and prevention guidelines. Results: Six processes were detected handling HD. During those processes, thirty HD were identified included in the hospital GFT and a safer alternative was found for 6 of them. The HD were classified into 4 risk categories based on those measures to be taken during the preparation and administration of each of them. Conclusions: The development and implementation of specific safety-work processes dealing with medication handling, allows hospital managers to accomplish effectively with their legal obligations about the area of prevention and provides healthcare professional staff with the adequate techniques and safety equipment to avoid possible dangers and risks of some drugs.

  18. Validation of a Previously Developed Geospatial Model That Predicts the Prevalence of Listeria monocytogenes in New York State Produce Fields.

    Science.gov (United States)

    Weller, Daniel; Shiwakoti, Suvash; Bergholz, Peter; Grohn, Yrjo; Wiedmann, Martin; Strawn, Laura K

    2016-02-01

    Technological advancements, particularly in the field of geographic information systems (GIS), have made it possible to predict the likelihood of foodborne pathogen contamination in produce production environments using geospatial models. Yet, few studies have examined the validity and robustness of such models. This study was performed to test and refine the rules associated with a previously developed geospatial model that predicts the prevalence of Listeria monocytogenes in produce farms in New York State (NYS). Produce fields for each of four enrolled produce farms were categorized into areas of high or low predicted L. monocytogenes prevalence using rules based on a field's available water storage (AWS) and its proximity to water, impervious cover, and pastures. Drag swabs (n = 1,056) were collected from plots assigned to each risk category. Logistic regression, which tested the ability of each rule to accurately predict the prevalence of L. monocytogenes, validated the rules based on water and pasture. Samples collected near water (odds ratio [OR], 3.0) and pasture (OR, 2.9) showed a significantly increased likelihood of L. monocytogenes isolation compared to that for samples collected far from water and pasture. Generalized linear mixed models identified additional land cover factors associated with an increased likelihood of L. monocytogenes isolation, such as proximity to wetlands. These findings validated a subset of previously developed rules that predict L. monocytogenes prevalence in produce production environments. This suggests that GIS and geospatial models can be used to accurately predict L. monocytogenes prevalence on farms and can be used prospectively to minimize the risk of preharvest contamination of produce. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  19. [Incidence and clinical risk factors for the development of diabetes mellitus in women with previous gestational diabetes].

    Science.gov (United States)

    Domínguez-Vigo, P; Álvarez-Silvares, E; Alves-Pérez M T; Domínguez-Sánchez, J; González-González, A

    2016-04-01

    Gestational diabetes is considered a variant of diabetes mellitus as they share a common pathophysiological basis: insulin resistance in target and insufficient secretion of it by pancreatic p-cell bodies. Pregnancy is a unique physiological situation provides an opportunity to identify future risk of diabetes mellitus. To determine the long-term incidence of diabetes mellitus in women who have previously been diagnosed with gestational diabetes and identifying clinical risk factors for developing the same. nested case-control cohort study. 671 patients between 1996 and 2009 were diagnosed with gestational diabetes were selected. The incidence of diabetes mellitus was estimated and 2 subgroups were formed: Group A or cases: women who develop diabetes mellitus after diagnosis of gestational diabetes. Group B or control: random sample of 71 women with a history of gestational diabetes in the follow-up period remained normoglycemic. Both groups were studied up to 18 years postpartum. By studying Kaplan Meier survival of the influence of different gestational variables it was obtained in the later development of diabetes mellitus with time parameter and COX models for categorical variables were applied. Significant variables were studied by multivariate Cox analysis. In all analyzes the Hazard ratio was calculated with confidence intervals at 95%. The incidence of diabetes mellitus was 10.3% in patients with a history of gestational diabetes. They were identified as risk factors in the index pregnancy to later development of diabetes mellitus: greater than 35 and younger than 27 years maternal age, BMI greater than 30 kg/m2, hypertensive disorders of pregnancy, insulin therapy, poor metabolic control and more than a complicated pregnancy with gestational diabetes. Clinical factors have been identified in the pregnancy complicated by gestational diabetes that determine a higher probability of progression to diabetes mellitus in the medium and long term.

  20. Planning policy, sustainability and housebuilder practices: The move into (and out of?) the redevelopment of previously developed land.

    Science.gov (United States)

    Karadimitriou, Nikos

    2013-05-01

    This paper explores the transformations of the housebuilding industry under the policy requirement to build on previously developed land (PDL). This requirement was a key lever in promoting the sustainable urban development agenda of UK governments from the early 1990s to 2010 and has survived albeit somewhat relaxed and permutated in the latest National Planning Policy Framework (NPPF). The paper therefore looks at the way in which the policy push towards densification and mixed use affected housebuilders' business strategy and practices and their ability to cope with the 2007 downturn of the housing market and its aftermath. It also points out the eventual feedback of some of these practices into planning policy. Following the gradual shift of British urban policy focus towards sustainability which started in the early 1990s, new configurations of actors, new skills, strategies and approaches to managing risk emerged in property development and housebuilding. There were at least two ways in which housebuilders could have responded to the requirements of developing long term mixed use high density projects on PDL. One way was to develop new products and to employ practices and combinations of practices involving phasing, a flexible approach to planning applications and innovative production methods. Alternatively, they could approach PDL development as a temporary turn of policy or view mixed use high density schemes as a niche market to be explored without drastically overhauling the business model of the entire firm. These transformations of the UK housebuilding sector were unfolding during a long period of buoyancy in the housing market which came to an end in 2007. Very little is known both about how housebuilder strategies and production practices evolved during the boom years as well as about how these firms coped with the effects of the 2007 market downturn. The paper draws on published data (company annual reports, government statistics) and primary

  1. Planning policy, sustainability and housebuilder practices: The move into (and out of?) the redevelopment of previously developed land

    Science.gov (United States)

    Karadimitriou, Nikos

    2013-01-01

    This paper explores the transformations of the housebuilding industry under the policy requirement to build on previously developed land (PDL). This requirement was a key lever in promoting the sustainable urban development agenda of UK governments from the early 1990s to 2010 and has survived albeit somewhat relaxed and permutated in the latest National Planning Policy Framework (NPPF). The paper therefore looks at the way in which the policy push towards densification and mixed use affected housebuilders’ business strategy and practices and their ability to cope with the 2007 downturn of the housing market and its aftermath. It also points out the eventual feedback of some of these practices into planning policy. Following the gradual shift of British urban policy focus towards sustainability which started in the early 1990s, new configurations of actors, new skills, strategies and approaches to managing risk emerged in property development and housebuilding. There were at least two ways in which housebuilders could have responded to the requirements of developing long term mixed use high density projects on PDL. One way was to develop new products and to employ practices and combinations of practices involving phasing, a flexible approach to planning applications and innovative production methods. Alternatively, they could approach PDL development as a temporary turn of policy or view mixed use high density schemes as a niche market to be explored without drastically overhauling the business model of the entire firm. These transformations of the UK housebuilding sector were unfolding during a long period of buoyancy in the housing market which came to an end in 2007. Very little is known both about how housebuilder strategies and production practices evolved during the boom years as well as about how these firms coped with the effects of the 2007 market downturn. The paper draws on published data (company annual reports, government statistics) and primary

  2. Integrated site investigation procedure for environment protection toward sustainable development

    International Nuclear Information System (INIS)

    Omar, R C; Roslan, R; Baharuddin, I N Z

    2013-01-01

    The spatial configuration of cities and their relationship to the urban environment has recently been the subject of empirical, theoretical and policy research. An awareness of environmental issues can assist policy makers, planners, developers and others to recognize the constraints imposed upon development due the physical environment especially in areas, which are susceptible to erosion, flooding and landslide. This paper highlights the key requirements for considering an assessment to protect our urban environment by incorporating three main factor i.e. policy practice, planning process and engineering investigation. Base on this three main factor the framework of the assessment is carried out. The assessment can be divided into three different categories, namely as investigation for planning, investigation for urban development and specialized investigation and mitigation. The minimum requirements for the planning and urban development investigation are listed. These guidelines suggest the level at which the various types of investigation should be carried out as well as the range of application, the scope and methodology to be used for different investigation. It is hoped that this procedure will provide guidance in the establishment and protection of urban ecosystem toward sustainable development.

  3. Development of AMS procedure for measurement of 93Zr

    Science.gov (United States)

    Lu, Wenting; Collon, Philippe; Kashiv, Yoav; Bowers, Matthew; Robertson, Daniel; Schmitt, Christopher

    2011-10-01

    The procedure for measuring 93Zr (t1/2 = 1.5 Ma) by AMS is currently being developed at the Nuclear Science Lab at the University of Notre Dame and we report on first experiments performed in this direction. AMS detection of 93Zr can potentially be applied to address astrophysical and environmental issues: (1) the measurement of the 92Zr(n,γ)93Zr reaction cross-section at nucleosynthesis s-process relevant temperatures, (2) the search for potential live 93Zr from a supernova in deep sea sediments, (3) hydrological and radioactive waste tracing. The measurement of 93Zr requires adequate separation from its stable isobar 93Nb. We are currently working on optimizing this separation by using the GasFilled Magnet technique with additional multiple dE measurements in a focal plane ionization chamber.

  4. Developing Physiologic Models for Emergency Medical Procedures Under Microgravity

    Science.gov (United States)

    Parker, Nigel; O'Quinn, Veronica

    2012-01-01

    Several technological enhancements have been made to METI's commercial Emergency Care Simulator (ECS) with regard to how microgravity affects human physiology. The ECS uses both a software-only lung simulation, and an integrated mannequin lung that uses a physical lung bag for creating chest excursions, and a digital simulation of lung mechanics and gas exchange. METI s patient simulators incorporate models of human physiology that simulate lung and chest wall mechanics, as well as pulmonary gas exchange. Microgravity affects how O2 and CO2 are exchanged in the lungs. Procedures were also developed to take into affect the Glasgow Coma Scale for determining levels of consciousness by varying the ECS eye-blinking function to partially indicate the level of consciousness of the patient. In addition, the ECS was modified to provide various levels of pulses from weak and thready to hyper-dynamic to assist in assessing patient conditions from the femoral, carotid, brachial, and pedal pulse locations.

  5. Criteria procedure development for tender in construction design

    Directory of Open Access Journals (Sweden)

    Malykha Galina Gennad’evna

    Full Text Available This article deals with the problem of criteria optimization in order to objectively evaluate the experience of an applicant (a project organization and the quality of a design product (project documentation. The methodology to be developed is based on introduction of new evaluation criteria (sub-criteria that in conjunction with the applicable criteria specified by the Law on the Contract System will allow developing the optimal procedure to evaluate competitive bids of the participants in tenders and determining the most appropriate candidate, with whom the contract will be further concluded. The article analyzes the existing criteria and their interaction with each other and describes the specifics of tenders for design in the form of open competition. The list decreases to three criteria, such as "contract price", "quality, functional and environmental characteristics of a procurement facility", "qualification of procurement participants, including availability of financial resources, equipment and other material resources necessary for the execution of the contract material resources, the presence of goodwill, professionals and other employees of a certain experience level". However, in order to upgrade the quality of assurance procedures for the design works to be performed, it was decided to apply new evaluation criteria (sub-criteria components, such as "availability of positive findings of the state out-of-departmental examination that are similar to the subject of competition, on a participant in placement of order", "availability of the certificate on approval of architectural and urban planning decisions that are similar to the subject of competition, on a participant in placement of order", "availability of the permit for the commissioning of facilities that are similar to the subject of competition, on a participant in placement of order", "availability of the contract for designer's supervision with a participant in placement of

  6. Development of an elevated temperature in-service welding procedure

    Energy Technology Data Exchange (ETDEWEB)

    Boring, Matthew A. [Edison Welding Institute (EWI), Columbus, OH (United States); Byrd, Bill [T.D. Williamson, Tulsa, OK (United States)

    2005-07-01

    Burn through is a concern when welding onto in-service pipelines. Burn through prediction using the Battelle model has been successfully applied to determine safe in-service welding parameters for a range of conditions, but is rarely used for elevated temperature applications. Recently completed work at EWI developed an in-service welding procedure for carbon steel pipelines up to 800 deg F (427 deg C). The Battelle model showed that increasing the temperature and heat input, but decreasing the wall thickness, increased burn through risk. Laboratory trial welds were metallographically analyzed and compared to Battelle model predictions and correlated well. Test plates were also placed in an 800 deg F (427 deg C) oven after welding for different times to determine if exposure at temperature affected the weld metal mechanical properties. Both plates passed destructive testing and a WPS was developed. For safety, the WPS specifies a maximum allowable heat input of 25 kJ/in. (1.0 kJ/mm) using 3/32-in. (2.4-mm) -diameter electrodes only. The two field trials on an operating pipeline verified the WPS by producing sound welds that were pressure tested and non-destructively examined upon cooling. NDE was performed during one field trial, at temperature, prior to making the hot tap but was unable to be done on the second due to technique limitations. (author)

  7. The Development of An Analytical Overlay Design Procedure

    Directory of Open Access Journals (Sweden)

    Djunaedi Kosasih

    2008-01-01

    Full Text Available Pavement structural evaluation using pavement modulus values resulting from back calculation process on non-destructive deflection data has been adopted to quantify objectively the conditions of existing pavements under various traffic loading and environmental conditions. However, such an advanced technique is not yet followed widely by advances in analytical overlay design procedures. One possible reason is perhaps due to its requirement to perform complex computations. A new module of computer program BackCalc has been developed to do that task based on the allowable maximum deflection criterion specified by the Asphalt Institute’83. The rationale is that adequate overlay thickness will be computed by iteration to result in theoretical maximum deflection that closely matches against the specified allowable maximum deflection. This paper outlines the major components of the program module illustrated by using a practical example. The overlay thickness obtained was found to be comparable with that of the known AASHTO’93 method

  8. Spectrophotometric determination of uranium with arsenazo previous liquid-liquid extraction and colour development in organic medium

    International Nuclear Information System (INIS)

    Palomares Delgado, F.; Vera Palomino, J.; Petrement Eguiluz, J. C.

    1964-01-01

    The determination of uranium with arsenazo is hindered by a great number of cation which form stable complexes with the reactive and may given rise to serious interferences. By studying the optimum conditions of uranium the extraction be means of tributylphosphate solutions dissolved in methylisobuthylketone, under conditions for previous masking of the interfering cations, an organic extract was obtained containing all the uranium together with small amounts of iron. The possible interference derived from the latter element is avoided by reduction with hydroxylammoniumchlorid followed by complex formation of the Fe(II)-ortophenantroline compound in alcoholic medium. (Author) 17 refs

  9. Development of ISA procedure for uranium fuel fabrication and enrichment facilities: overview of ISA procedure and its application

    International Nuclear Information System (INIS)

    Yamate, Kazuki; Yamada, Takashi; Takanashi, Mitsuhiro; Sasaki, Noriaki

    2013-01-01

    Integrated Safety Analysis (ISA) procedure for uranium fuel fabrication and enrichment facilities has been developed for aiming at applying risk-informed regulation to these uranium facilities. The development has carried out referring to the ISA (NUREG-1520) by the Nuclear Regulatory Commission (NRC). The paper presents purpose, principles and activities for the development of the ISA procedure, including Risk Level (RL) matrix and grading evaluation method of IROFS (Items Relied on for Safety), as well as general description and features of the procedure. Also described in the paper is current status in application of risk information from the ISA. Japanese four licensees of the uranium facilities have been conducting ISA for their representative processes using the developed procedure as their voluntary safety activities. They have been accumulating experiences and knowledge on the ISA procedure and risk information through the field activities. NISA (Nuclear and Industrial Safety Agency) and JNES (Japan Nuclear Energy Safety Organization) are studying how to use such risk information for the safety regulation of the uranium facilities, taking into account the licensees' experiences and knowledge. (authors)

  10. Synchronous development of breast cancer and chest wall fibrosarcoma after previous mantle radiation for Hodgkin's disease

    Energy Technology Data Exchange (ETDEWEB)

    Patlas, Michael [Hamilton General Hospital, Department of Radiology, Hamilton, ON (Canada); McCready, David [University Health Network and Mount Sinai Hospital, Department of Surgery, Toronto, ON (Canada); Kulkarni, Supriya; Dill-Macky, Marcus J. [University Health Network and Mount Sinai Hospital, Department of Medical Imaging, Toronto, ON (Canada)

    2005-09-01

    Survivors of Hodgkin's disease are at increased risk of developing a second malignant neoplasm, including breast carcinoma and sarcoma. We report the first case of synchronous development of chest wall fibrosarcoma and breast carcinoma after mantle radiotherapy for Hodgkin's disease. Mammographic, sonographic and MR features are demonstrated. (orig.)

  11. Developing operating procedures for a low-level radioactive waste disposal facility

    International Nuclear Information System (INIS)

    Sutherland, A.A.; Miner, G.L.; Grahn, K.F.; Pollard, C.G.

    1993-10-01

    This document is intended to assist persons who are developing operating and emergency procedures for a low-level radioactive waste disposal facility. It provides 25 procedures that are considered to be relatively independent of the characteristics of a disposal facility site, the facility design, and operations at the facility. These generic procedures should form a good starting point for final procedures on their subjects for the disposal facility. In addition, this document provides 55 annotated outlines of other procedures that are common to disposal facilities. The annotated outlines are meant as checklists to assist the developer of new procedures

  12. Developing operating procedures for a low-level radioactive waste disposal facility

    Energy Technology Data Exchange (ETDEWEB)

    Sutherland, A.A.; Miner, G.L.; Grahn, K.F.; Pollard, C.G. [Rogers and Associates Engineering Corp., Salt Lake City, UT (United States)

    1993-10-01

    This document is intended to assist persons who are developing operating and emergency procedures for a low-level radioactive waste disposal facility. It provides 25 procedures that are considered to be relatively independent of the characteristics of a disposal facility site, the facility design, and operations at the facility. These generic procedures should form a good starting point for final procedures on their subjects for the disposal facility. In addition, this document provides 55 annotated outlines of other procedures that are common to disposal facilities. The annotated outlines are meant as checklists to assist the developer of new procedures.

  13. Development of Procedures for Assessing the Impact of Vocational Education Research and Development on Vocational Education (Project IMPACT). Volume 4--A Case Study of Illinois Projects in Horticulture.

    Science.gov (United States)

    Hook, Colin; Ethridge, James

    As part of Project IMPACT's efforts to identify and develop procedures for complying with the impact requirements of Public Law 94-482, a case study was made of Illinois Projects in Horticulture. Fourteen horticulture projects in high schools and junior colleges were discovered through a previous study, personal interviews with two University of…

  14. Inflatable Antenna for CubeSat: Extension of the Previously Developed S-Band Design to the X-Band

    Science.gov (United States)

    Babuscia, Alessandra; Choi, Thomas; Cheung, Kar-Ming; Thangavelautham, Jekan; Ravichandran, Mithun; Chandra, Aman

    2015-01-01

    The inflatable antenna for CubeSat is a 1 meter antenna reflector designed with one side reflective Mylar, another side clear Mylar with a patch antenna at the focus. The development of this technology responds to the increasing need for more capable communication systems to allow CubeSats to operate autonomously in interplanetary missions. An initial version of the antenna for the S-Band was developed and tested in both anechoic chamber and vacuum chamber. Recent developments in transceivers and amplifiers for CubeSat at X-band motivated the extension from the S-Band to the X-Band. This paper describes the process of extending the design of the antenna to the X-Band focusing on patch antenna redesign, new manufacturing challenges and initial results of experimental tests.

  15. The reliability of the Associate Platinum digital foot scanner in measuring previously developed footprint characteristics: a technical note.

    Science.gov (United States)

    Papuga, M Owen; Burke, Jeanmarie R

    2011-02-01

    An ink pad and paper, pressure-sensitive platforms, and photography have previously been used to collect footprint data used in clinical assessment. Digital scanners have been widely used more recently to collect such data. The purpose of this study was to evaluate the intra- and interrater reliability of a flatbed digital image scanning technology to capture footprint data. This study used a repeated-measures design on 32 (16 male 16 female) healthy subjects. The following measured indices of footprint were recorded from 2-dimensional images of the plantar surface of the foot recorded with an Associate Platinum (Foot Levelers Inc, Roanoke, VA) digital foot scanner: Staheli index, Chippaux-Smirak index, arch angle, and arch index. Intraclass correlation coefficient (ICC) values were calculated to evaluate intrarater, interday, and interclinician reliability. The ICC values for intrarater reliability were greater than or equal to .817, indicating an excellent level of reproducibility in assessing the collected images. Analyses of variance revealed that there were no significant differences between raters for each index (P > .05). The ICC values also indicated excellent reliability (.881-.971) between days and clinicians in all but one of the indices of footprint, arch angle (.689), with good reliability between clinicians. The full-factorial analysis of variance model did not reveal any interaction effects (P > .05), which indicated that indices of footprint were not changing across days and clinicians. Scanning technology used in this study demonstrated good intra- and interrater reliability measurements of footprint indices, as demonstrated by high ICC values. Copyright © 2011 National University of Health Sciences. Published by Mosby, Inc. All rights reserved.

  16. Hemoglobin-Based Oxygen Carrier (HBOC) Development in Trauma: Previous Regulatory Challenges, Lessons Learned, and a Path Forward.

    Science.gov (United States)

    Keipert, Peter E

    2017-01-01

    Historically, hemoglobin-based oxygen carriers (HBOCs) were being developed as "blood substitutes," despite their transient circulatory half-life (~ 24 h) vs. transfused red blood cells (RBCs). More recently, HBOC commercial development focused on "oxygen therapeutic" indications to provide a temporary oxygenation bridge until medical or surgical interventions (including RBC transfusion, if required) can be initiated. This included the early trauma trials with HemAssist ® (BAXTER), Hemopure ® (BIOPURE) and PolyHeme ® (NORTHFIELD) for resuscitating hypotensive shock. These trials all failed due to safety concerns (e.g., cardiac events, mortality) and certain protocol design limitations. In 2008 the Food and Drug Administration (FDA) put all HBOC trials in the US on clinical hold due to the unfavorable benefit:risk profile demonstrated by various HBOCs in different clinical studies in a meta-analysis published by Natanson et al. (2008). During standard resuscitation in trauma, organ dysfunction and failure can occur due to ischemia in critical tissues, which can be detected by the degree of lactic acidosis. SANGART'S Phase 2 trauma program with MP4OX therefore added lactate >5 mmol/L as an inclusion criterion to enroll patients who had lost sufficient blood to cause a tissue oxygen debt. This was key to the successful conduct of their Phase 2 program (ex-US, from 2009 to 2012) to evaluate MP4OX as an adjunct to standard fluid resuscitation and transfusion of RBCs. In 2013, SANGART shared their Phase 2b results with the FDA, and succeeded in getting the FDA to agree that a planned Phase 2c higher dose comparison study of MP4OX in trauma could include clinical sites in the US. Unfortunately, SANGART failed to secure new funding and was forced to terminate development and operations in Dec 2013, even though a regulatory path forward with FDA approval to proceed in trauma had been achieved.

  17. National Economic Development Procedures Manual - Agricultural Flood Damage,

    Science.gov (United States)

    1987-10-01

    the planning process and the NED evaluacion ’- ". procedures for agriculture, as described in the P&G, are thei presented. Also identified are some...be examined to determine the uncertainty inherent in the data or in various assumptions of future economic, demographic, social , attitudinal...8217,- % % .. . . . .- 2.. - A J Risk and uncertainty arise from measurement errors and from the underlying variability of complex natural, social , and economic si’uations

  18. Towards a comprehensive procedure for developing measurement scales for cross-cultural management research

    NARCIS (Netherlands)

    Caramelli, M.; van de Vijver, F.J.R.

    2013-01-01

    A procedure for developing and testing measurement scales for use in cross-cul -tural comparative management research is described. The procedure emphasizes the combination of adequate instrument design if a new instrument is used or adequate adaptation procedures if working with an existing

  19. Development of use of an Operational Procedure Information System (OPIS) for future space missions

    Science.gov (United States)

    Illmer, N.; Mies, L.; Schoen, A.; Jain, A.

    1994-01-01

    A MS-Windows based electronic procedure system, called OPIS (Operational Procedure Information System), was developed. The system consists of two parts, the editor, for 'writing' the procedure and the notepad application, for the usage of the procedures by the crew during training and flight. The system is based on standardized, structured procedure format and language. It allows the embedding of sketches, photos, animated graphics and video sequences and the access to off-nominal procedures by linkage to an appropriate database. The system facilitates the work with procedures of different degrees of detail, depending on the training status of the crew. The development of a 'language module' for the automatic translation of the procedures, for example into Russian, is planned.

  20. Development of Policies, Institutions and Procedures for Water Reuse

    Science.gov (United States)

    Demouche, L.; Pfiefer, J.; Hanson, A.; Skaggs, R.

    2009-12-01

    In the arid, water scarce region of New Mexico and West Texas there is growing interest in the potential for water reuse to extend existing supplies and mitigate drought shortage impacts. There are no new sources of water in New Mexico, except reclaimed water. Communities and individuals are uncertain about and have many unanswered questions about polices, institutions involved (agencies), legal and regulatory requirements, and procedures governing water reuse. Issues to be addressed by this project include: the legal ability to reuse water, ownership of water rights, downstream or third party impacts, regulatory and procedural requirements, water quality concerns, state and local agency involvement, and cost effectiveness of water reuse compared to alternative sources. Presently, there is very little implementation or directives in New Mexico policy that addresses reuse, reclamation, or recycled water. The only regulations pertaining to reuse is New Mexico Environmental Department currently allows the use of reclaimed domestic wastewater for irrigation of golf courses and green spaces, which is listed in the Policy for the Above Ground Use of Reclaimed Domestic Wastewater (NMED, 2003). This document identifies the various reclaimed quality classifications that are required for specific applications and the permits required for application. This document does not identify or address policy applications on the distribution, ownership, or trading of reclaimed water. Even though reclaimed water reuse projects are currently being implemented in many cities in the U.S., mainly for commercial and municipal irrigation (golf courses and green space), its potential has not yet been exploited. A policy analysis matrix (PAM) is being designed to identify and examine the policy framework and consequences of non-policy implementation for decision makers and interest groups and assist them in understanding the consequences of policy actions and project outcomes if no laws or

  1. Good practices with respect to the development and use of nuclear power plant procedures

    International Nuclear Information System (INIS)

    1998-12-01

    This technical publication is intended to provide information to nuclear power plant managers concerning good practices in respect to the development and use of NPP procedures. It is a part of an ongoing project on nuclear power plant instrumentation and control and is based on lessons learned from NPPs and utilities. The overall objective of this project is to provide systematic guidance on current and emerging instrumentation and control technologies including: protection and automation systems, control rooms, operator support systems, training simulators and human factors. It is intended to be applicable to NPPs in Member States that are in operation, under construction or being commissioned. The good practices described are consistent with the IAEA Safety Series recommendations with respect to the development and use of NPP procedures including the four categories: administrative procedures, operating procedures (normal, alarm response, abnormal and emergency procedures), maintenance and technical support procedures, and testing and surveillance procedures

  2. Developing Conceptual Understanding and Procedural Skill in Mathematics: An Iterative Process.

    Science.gov (United States)

    Rittle-Johnson, Bethany; Siegler, Robert S.; Alibali, Martha Wagner

    2001-01-01

    Proposes that conceptual and procedural knowledge develop in an iterative fashion and improved problem representation is one mechanism underlying the relations between them. Two experiments were conducted with 5th and 6th grade students learning about decimal fractions. Results indicate conceptual and procedural knowledge do develop, iteratively,…

  3. [Dental education and preclinical procedures to develop indirect vision].

    Science.gov (United States)

    Díaz Torres, M J; Santos Vallejo, C; Yanguas Bayona, M; Santos Carrillo Baracaldo, J; Vega del Barrio, J M

    1991-05-01

    The technological advance and the development of the odontologic profession, requires the gradual incorporation of more accurate psycho-motrice methods. The aim of this report is the presentation of the systems elaborated for the development of the students' and odontologists' psycho-motive skill. This report describes the method known as "reflection box", for the learning of indirect vision. In order to achieve a training, for the correct odontologic practice, in ergonomic positions that prevent skeleton-muscle disorders resulted from inadequate professional practices, exercises in two and three dimensions should be carried out with said box.

  4. Development of an Evaluative Procedure for Clinical Clerkships.

    Science.gov (United States)

    And Others; Pancorbo, Salvador

    1980-01-01

    In order to evaluate the clinical competencies of graduate pharmacy students upon the completion of a medicine rotation, an oral examination has been developed that requires students to present data and defend decisions. Objectives, responsibilities, and competencies required by the rotation and nine sample exam questions are appended. (JMD)

  5. Test Item Development: Validity Evidence from Quality Assurance Procedures.

    Science.gov (United States)

    Downing, Steven M.; Haladyna, Thomas M.

    1997-01-01

    An ideal process is outlined for test item development and the study of item responses to ensure that tests are sound. Qualitative and quantitative methods are used to assess the item-level validity evidence for high-stakes examinations. A checklist for assessment is provided. (SLD)

  6. Making choices: The development of an assessment procedure.

    NARCIS (Netherlands)

    Oppenheimer, L.J.T.; John-Roberts, E.; Taal, M.

    1998-01-01

    This study developed an instrument for the assessment of children's understanding of processes involved in the formulation of goals, making choices, and the role of own responsibility in making choices (i.e., planning components). In Study 1, a list of concepts consisting of 54 items was presented

  7. Development of an efficient procedure for the preconcentration of ...

    African Journals Online (AJOL)

    A sensitive and selective preconcentration method has been developed for copper(II) using modified sawdust as an adsorbent. Sawdust was chemically modified with diethylenetriamine. Copper as CuCl42- was retained by the adsorbent in the column, eluted by nitric acid and subsequently determined by flame atomic ...

  8. Development of analytical procedures for coprocessing. Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, R.P.; Green, J.B.; Vogh, J.W.

    1991-07-01

    One phase of improving understanding of the fundamental chemistry of coprocessing involves development of the ability to distinguish between products originating from coal versus those originating from petroleum resid. A primary objective of this project was to develop analytical techniques to determine the source (coal versus resid) of the various compound types found in coprocessing products. A corollary objective was to develop an expanded knowledge of the detailed composition of coprocessing products. Two approaches were evaluated for distinguishing between products originating from coal and those originating from petroleum resid. One was based on the use of carbon isotope ratios and the other was based on variations in compound classes in response to changes in the ratio of coal to resid in the coprocessing feed. Other researchers using carbon isotope ratios to determine the origin of products have typically examined distillation fractions. This project involved determination of the origin of chemical classes (e.g., saturates, neutral aromatics, phenols, indoles, etc.) rather than distillate classes. Maya resid and Illinois No. 6 coal (with coal feed varying from 2 to 40 percent) were coprocessed in a batch autoclave to obtain products for detailed analysis.

  9. Methodology for development of health physics procedures at research reactors in agreement states

    International Nuclear Information System (INIS)

    Woodard, R.C.; Bauer, T.L.; Wehring, B.W.

    1991-01-01

    The University of Texas at Austin is awaiting final license approval to operate a new 1 MW TRIGA reactor for teaching and research. All reactor and laboratory operations, experiments, and monitoring are carried out under health physics procedures that address to ensure consideration of all applicable documents as references in order to comply with the regulations and accepted good practices. This paper examines the development of one procedure Radioactive Material Control by use of the method. The process is examined as a tool to apply to any health physics procedure development. Further discussion focuses on the regulatory anomalies observed during development of the procedure and presents the arguments for the authors resolution of these issues. The design of the reactor facility is also detailed to allow for understanding of the problems encountered during procedural development

  10. Development of quality assurance procedures for production of sealed radiation source

    International Nuclear Information System (INIS)

    Nam, J. H.; Han, H. S.; Cho, W. K.; Kim, S. D.; Hong, S. B.; Chang, K. D.; Lim, N. J.; Lee, Y. G.; Kim, K. H.

    2001-11-01

    The quality assurance procedures for sealed radiation sources production using HANARO and RIPF have been developed. The detailed quality assurance procedures are essential to manage the whole work process effectively and ensure the quality of the produced sealed sources. Through applying this quality assurance procedures to the entire production works of the sealed radiation sources, it is expected that the quality of the products, the safety of the works and the satisfaction of the customers will be increased

  11. Development of quality assurance procedures for production of sealed radiation source

    CERN Document Server

    Nam, J H; Cho, W K; Han, H S; Hong, S B; Kim, K H; Kim, S D; Lee, Y G; Lim, N J

    2001-01-01

    The quality assurance procedures for sealed radiation sources production using HANARO and RIPF have been developed. The detailed quality assurance procedures are essential to manage the whole work process effectively and ensure the quality of the produced sealed sources. Through applying this quality assurance procedures to the entire production works of the sealed radiation sources, it is expected that the quality of the products, the safety of the works and the satisfaction of the customers will be increased.

  12. Development of zero conditioning procedure for coal reverse flotation

    Energy Technology Data Exchange (ETDEWEB)

    D.P. Patil; J.S. Laskowski [University of British Columbia, Vancouver, BC (Canada). Mining Engineering Department

    2008-04-15

    The zero conditioning method was developed to facilitate the flotation of gangue minerals in the reverse coal flotation process. Batch and continuous methods were developed to maintain the zero conditioning principle during reverse flotation. Batch zero conditioning was achieved by adding the required amount of DTAB in one step, as soon as the air was introduced into the system. The continuous zero conditioning method involves uninterrupted addition of DTAB through a specially built sparger in the form of aerosol during the flotation experiment. This produces active bubbles that carry collector. The addition of DTAB in the form of aerosol during reverse flotation proved to be better in reducing the ash of a sub-bituminous (LS-26) coal from 34.7% to 22.9% with a froth product (gangue) yield of 36.8% without any depressant. In the presence of coal depressant (dextrin, 0.5 kg/t), the ash content of LS-26 coal was reduced from 34.7% to 16.5% at a clean coal yield of 55%, whereas the conventional (forward) flotation with fuel oil provided a clean coal containing 16.5% ash with only 29.2% yield. These results prove that flotation of gangue minerals is very much improved by maintaining zero conditioning time conditions in a coal reverse flotation process.

  13. Corresponding control of the administration - procedural development and deadlocks

    International Nuclear Information System (INIS)

    Breuer, R.

    1980-01-01

    The author proceeds from a decision of the Higher Administrative Court of Lueneburg of February 2, 1979 which limits the execution of a partial construction permit for a nuclear power plant to the extent that 'the approved plant components may and will only be used under certain conditions'. He critically reflects on the development of administrative legal protection. In principle, corresponding control of the administration leads to a latent change in the function of appeals aiming at cassation. As a rule, this is not against the law, since sect. 80 of the VwGO acknowledges 'individual interim regulations'. In this case it is a condition of a cancelling nature. The discussion of acknowledged and problematic cases of judicial decisions made under certain conditions is followed by the explanation that the Higher Administrative Court of Lueneburg has delegated the decision which is incumbent upon the Court to the Commission on Reactor Safety. Such a delegation of jurisdiction is contradictory to the constitutional postulate of Art. 19/IV and 91 of the Basic Law. (HSCH) [de

  14. Development and application of a welding procedure for remote repair of Magnox reactor internal components

    International Nuclear Information System (INIS)

    Morgan-Warren, E.J.

    1988-01-01

    This paper summarises the development and application of an all-welding repair method for reinforcing magnox reactor internal components. The development was dominated by the necessity for remote operation and the environmental constraints, in particular the oxide covering on the steel reactor structure. The choice of welding process is described, together with the development of the procedure for remote operation. The quality assurance procedure, including the verification of the technique and monitoring of the repair operation, is discussed. (author)

  15. [Anthelmintic resistance in ruminants: development, diagnostics, and procedures].

    Science.gov (United States)

    Knubben-Schweizer, Gabriela; Pfister, Kurt

    2017-08-10

    Anthelmintic resistance of gastrointestinal nematodes in small ruminants, but also in cattle and horses, is now found worldwide. The reason for increasing anthelmintic resistance is, in particular, the extensive use of all the anthelmintic agents available on the market. A non-targeted use leads to the selection of naturally occurring resistance genes within parasite populations. The most practical method for evaluating the efficacy of an anthelmintic is the fecal egg-count reduction test. To reduce the rate of anthelmintic resistance development, the available active substances must be applied less and in a targeted manner. When applying targeted (selective) treatment, part of the herd is left untreated. Therefore, it is necessary to identify the animals that require treatment for health or economic reasons. To decide on anthelmintic treatment, findings can be collected from single animals or from a group of animals in a herd. To determine which groups of animals are to be treated within a herd (targeted treatment), pooled fecal samples (cattle and small ruminants), serum pepsinogen concentration (cattle), or Ostertagia ostertagi antibodies in the bulk milk (cattle) can be analyzed. For individual animal (targeted selective) treatment, criteria including fecal egg count (cattle and small ruminants), conjuctival color as an indicator for infection with Haemonchus contortus (FAMACHA ® , small ruminants), body condition in adult animals (small ruminants), weight gain in juvenile animals (cattle and small ruminants), and the consistency of the feces (small ruminants) are used. These decision criteria can also be combined to enhance the informative value. Furthermore, an efficacy test of the anthelmintics used should be performed regularly at the beginning of the pasture season. During the pasture season, a low infection pressure should be maintained by pasture management strategies. The goal of sustainable parasite management is the reduction of anthelmintic

  16. Bilingualism and Procedural Learning in Typically Developing Children and Children with Language Impairment

    Science.gov (United States)

    Park, Jisook; Miller, Carol A.; Rosenbaum, David A.; Sanjeevan, Teenu; van Hell, Janet G.; Weiss, Daniel J.; Mainela-Arnold, Elina

    2018-01-01

    Purpose: The aim of this study was to investigate whether dual language experience affects procedural learning ability in typically developing children and in children with specific language impairment (SLI). Method: We examined procedural learning in monolingual and bilingual school-aged children (ages 8-12 years) with and without SLI. The…

  17. Development of an Assessment Procedure for Seawater Intrusion Mitigation

    Science.gov (United States)

    Hsi Ting, F.; Yih Chi, T.

    2017-12-01

    The Pingtung Plain is one of the areas with extremely plentiful groundwater resources in Taiwan. Due to that the application of the water resource is restricted by significant variation of precipitation between wet and dry seasons, groundwater must be used as a recharge source to implement the insufficient surface water resource during dry seasons. In recent years, the coastal aquaculture rises, and the over withdrawn of groundwater by private well results in fast drop of groundwater level. Then it causes imbalance of groundwater supply and leads to serious seawater intrusion in the coastal areas. The purpose of this study is to develop an integrated numerical model of groundwater resources and seawater intrusion. Soil and Water Assessment Tool (SWAT), MODFLOW and MT3D models were applied to analyze the variation of the groundwater levels and salinity concentration to investigate the correlation of parameters, which are used to the model applications in order to disposal saltwater intrusion. The data of groundwater levels, pumping capacity and hydrogeological data to were collected to build an integrated numerical model. Firstly, we will collect the information of layered aquifer and the data of hydrological parameters to build the groundwater numerical model at Pingtung Plain, and identify the amount of the groundwater which flow into the sea. In order to deal with the future climate change conditions or extreme weather conditions, we will consider the recharge with groundwater model to improve the seawater intrusion problem. The integrated numerical model which describes that seawater intrusion to deep confined aquifers and shallow unsaturated aquifers. Secondly, we will use the above model to investigate the weights influenced by different factors to the amount area of seawater intrusion, and predict the salinity concentration distribution of evaluation at coastal area of Pingtung Plain. Finally, we will simulate groundwater recharge/ injection at the coastal

  18. Development of a standard operating procedure for analysis of ammonia concentrations in coal fly ash.

    Science.gov (United States)

    2015-04-01

    Research was performed to support the development and recommendation of a standard operating : procedure (SOP) for analyzing the ammonia content in fly ash intended for use in concrete. A review : of existing ash producers found that several differen...

  19. Development of automated generation system of accidental operating procedures for a PWR

    International Nuclear Information System (INIS)

    Artaud, J.L.

    1991-06-01

    The aim of the ACACIA project is to develop an automated generation system of accident operating procedures for a PWR. This research and development study, common at CEA and EDF, has two objectives: at mean-dated the realization of a validation tool and a procedure generation; at long-dated the dynamic generation of real time procedures. This work is consecrated at the realization of 2 prototypes. These prototypes and the technics used are described in detail. The last chapter explores the perspectives given by this type of tool [fr

  20. Developments in the preparation of operating procedures for emergency conditions of nuclear power plants

    International Nuclear Information System (INIS)

    1985-06-01

    In recent years a substantial effort has been devoted by the nuclear community to extend Emergency Operating Procedures (EOPs) to cover all conceivable events and to develop procedure formats that transmit the essential guidance to operators in an optimum way. The information given in this report is based upon the most recent developments in formulating and applying EOPs. It should therefore provide guidance to those involved in preparing or reviewing EOPs on the scope, technical basis, organization and format of such procedures. It also outlines the actions required to validate the adequacy and applicability of these procedures so that the correct operator actions are achieved. Examples are given to illustrate the developments in some Member States

  1. PREVIOUS SECOND TRIMESTER ABORTION

    African Journals Online (AJOL)

    PNLC

    PREVIOUS SECOND TRIMESTER ABORTION: A risk factor for third trimester uterine rupture in three ... for accurate diagnosis of uterine rupture. KEY WORDS: Induced second trimester abortion - Previous uterine surgery - Uterine rupture. ..... scarred uterus during second trimester misoprostol- induced labour for a missed ...

  2. New Procedure to Develop Lumped Kinetic Models for Heavy Fuel Oil Combustion

    KAUST Repository

    Han, Yunqing

    2016-09-20

    A new procedure to develop accurate lumped kinetic models for complex fuels is proposed, and applied to the experimental data of the heavy fuel oil measured by thermogravimetry. The new procedure is based on the pseudocomponents representing different reaction stages, which are determined by a systematic optimization process to ensure that the separation of different reaction stages with highest accuracy. The procedure is implemented and the model prediction was compared against that from a conventional method, yielding a significantly improved agreement with the experimental data. © 2016 American Chemical Society.

  3. From analogue to apps--developing an app to prepare children for medical imaging procedures.

    Science.gov (United States)

    Williams, Gigi; Greene, Siobhan

    2015-01-01

    The Royal Children's Hospital (RCH) in Melbourne has launched a world-first app for children that will help reduce anxiety and the need for anesthesia during medical imaging procedures. The free, game-based app, "Okee in Medical Imaging", helps children aged from four to eight years to prepare for all medical imaging procedures--X-ray, CT, MRI, ultrasound, nuclear medicine, and fluoroscopy. The app is designed to reduce anticipatory fear of imaging procedures, while helping to ensure that children attend imaging appointments equipped with the skills required for efficient and effective scans to be performed. This paper describes how the app was developed.

  4. Ameloblastic fibroma: a stage in the development of a hamartomatous odontoma or a true neoplasm? Critical analysis of 162 previously reported cases plus 10 new cases.

    Science.gov (United States)

    Buchner, Amos; Vered, Marilena

    2013-11-01

    To analyze neoplastic and hamartomatous variants of ameloblastic fibromas (AFs). Analysis of 172 cases (162 previously reported, 10 new). AF emerged as a lesion primarily of children and adolescents (mean age, 14.9 years), with about 80% diagnosed when odontogenesis is completed (age, 22 years are considered true neoplasms, while those in younger patients may be either true neoplasms or odontomas in early stages of development. Although the histopathology of hamartomatous and neoplastic variants of AF are indistinguishable, clinical and radiologic features can be of some help to distinguish between them. Asymptomatic small unilocular lesions with no or minimal bone expansion in young individuals are likely to be developing odontomas, and large, expansile lesions with extensive bone destruction are neoplasms. Copyright © 2013 Elsevier Inc. All rights reserved.

  5. Procedural learning across the lifespan: A systematic review with implications for atypical development.

    Science.gov (United States)

    Zwart, Fenny S; Vissers, Constance Th W M; Kessels, Roy P C; Maes, Joseph H R

    2017-10-08

    This systematic review aimed to investigate procedural learning across the lifespan in typical and atypical development. Procedural learning is essential for the development of everyday skills, including language and communication skills. Although procedural learning efficiency has been extensively studied, there is no consensus yet on potential procedural learning changes during development and ageing. Currently, three conflicting models regarding this trajectory exist: (1) a model of age invariance; (2a) a model with a peak in young adulthood; and (2b) a model with a plateau in childhood followed by a decline. The aims of this study were (1) to investigate this debate on procedural learning across the lifespan by systematically reviewing evidence for each model from studies using the serial reaction time task; and (2) to review procedural learning in autism spectrum disorder (ASD) and specific language impairment (SLI), two developmental disorders characterized by deficits in communication skills, in the light of these models. Our findings on typical development strongly support a model of age-related changes (Model 2a or 2b) and show that mixed findings regarding the developmental trajectory during childhood can be explained by methodological differences across studies. Applying these conclusions to systematic reviews of studies of ASD and SLI makes it clear that there is a strong need for the inclusion of multiple age groups in these clinical studies to model procedural learning in atypical development. Clinical implications of the findings are discussed. Future research should focus on the role of declarative learning in both typical and atypical development. © 2017 The British Psychological Society.

  6. Interpreting "Personality" Taxonomies: Why Previous Models Cannot Capture Individual-Specific Experiencing, Behaviour, Functioning and Development. Major Taxonomic Tasks Still Lay Ahead.

    Science.gov (United States)

    Uher, Jana

    2015-12-01

    As science seeks to make generalisations, a science of individual peculiarities encounters intricate challenges. This article explores these challenges by applying the Transdisciplinary Philosophy-of-Science Paradigm for Research on Individuals (TPS-Paradigm) and by exploring taxonomic "personality" research as an example. Analyses of researchers' interpretations of the taxonomic "personality" models, constructs and data that have been generated in the field reveal widespread erroneous assumptions about the abilities of previous methodologies to appropriately represent individual-specificity in the targeted phenomena. These assumptions, rooted in everyday thinking, fail to consider that individual-specificity and others' minds cannot be directly perceived, that abstract descriptions cannot serve as causal explanations, that between-individual structures cannot be isomorphic to within-individual structures, and that knowledge of compositional structures cannot explain the process structures of their functioning and development. These erroneous assumptions and serious methodological deficiencies in widely used standardised questionnaires have effectively prevented psychologists from establishing taxonomies that can comprehensively model individual-specificity in most of the kinds of phenomena explored as "personality", especially in experiencing and behaviour and in individuals' functioning and development. Contrary to previous assumptions, it is not universal models but rather different kinds of taxonomic models that are required for each of the different kinds of phenomena, variations and structures that are commonly conceived of as "personality". Consequently, to comprehensively explore individual-specificity, researchers have to apply a portfolio of complementary methodologies and develop different kinds of taxonomies, most of which have yet to be developed. Closing, the article derives some meta-desiderata for future research on individuals' "personality".

  7. Development of QC Procedures for Ocean Data Obtained by National Research Projects of Korea

    Science.gov (United States)

    Kim, S. D.; Park, H. M.

    2017-12-01

    To establish data management system for ocean data obtained by national research projects of Ministry of Oceans and Fisheries of Korea, KIOST conducted standardization and development of QC procedures. After reviewing and analyzing the existing international and domestic ocean-data standards and QC procedures, the draft version of standards and QC procedures were prepared. The proposed standards and QC procedures were reviewed and revised by experts in the field of oceanography and academic societies several times. A technical report on the standards of 25 data items and 12 QC procedures for physical, chemical, biological and geological data items. The QC procedure for temperature and salinity data was set up by referring the manuals published by GTSPP, ARGO and IOOS QARTOD. It consists of 16 QC tests applicable for vertical profile data and time series data obtained in real-time mode and delay mode. Three regional range tests to inspect annual, seasonal and monthly variations were included in the procedure. Three programs were developed to calculate and provide upper limit and lower limit of temperature and salinity at depth from 0 to 1550m. TS data of World Ocean Database, ARGO, GTSPP and in-house data of KIOST were analysed statistically to calculate regional limit of Northwest Pacific area. Based on statistical analysis, the programs calculate regional ranges using mean and standard deviation at 3 kind of grid systems (3° grid, 1° grid and 0.5° grid) and provide recommendation. The QC procedures for 12 data items were set up during 1st phase of national program for data management (2012-2015) and are being applied to national research projects practically at 2nd phase (2016-2019). The QC procedures will be revised by reviewing the result of QC application when the 2nd phase of data management programs is completed.

  8. Development of Game-Like Simulations for Procedural Knowledge in Healthcare Education

    Science.gov (United States)

    Torrente, Javier; Borro-Escribano, Blanca; Freire, Manuel; del Blanco, Ángel; Marchiori, Eugenio J.; Martinez-Ortiz, Iván; Moreno-Ger, Pablo; Fernández-Manjón, Baltasar

    2014-01-01

    We present EGDA, an educational game development approach focused on the teaching of procedural knowledge using a cost-effective approach. EGDA proposes four tasks: analysis, design, implementation, and quality assurance that are subdivided in a total of 12 subtasks. One of the benefits of EGDA is that anyone can apply it to develop a game since…

  9. Development of automated operating procedure system using fuzzy colored petri nets for nuclear power plants

    International Nuclear Information System (INIS)

    Lee, Seung Jun; Seong, Poong Hyun

    2004-01-01

    In this work, AuTomated Operating Procedure System (ATOPS) is developed. ATOPS is an automation system for emergency operation of a nuclear power plant (NPP) and it can monitor signals, diagnose statuses, and generate control actions according to corresponding operating procedures without any human operator's help. Main functions of ATOPS are an anomaly detection function and a procedure execution function but only the procedure execution function is implemented in this work because this work is just the first step. In the procedure execution function, operating procedures of NPPs are analyzed and modeled using Fuzzy Colored Petri Nets (FCPN) and executed depending on decision making of the inference engine. In this work, ATOPS prototype is developed to demonstrate its feasibility and it is also validated using the FISA-2/WS simulator. The validation is performed for the cases of a loss of coolant accident (LOCA) and a steam generator tube rupture (SGTR). The simulation results show that ATOPS works correctly in the emergency situations

  10. COPMA-III: a tool for developing effective computerised procedure systems

    International Nuclear Information System (INIS)

    Bisio, R.; Hulsund, J.E.; NiIsen, S.

    2001-01-01

    The management of complicated work processes is often described in terms of procedures. Traditionally, the way to instruct operators has been through paper-based procedure manuals. However, the availability of powerful computer technology has led to development of Computerised Procedures Systems, CPS. Such systems offer assistance to the operators in procedure execution, providing services like automatic control of plant conditions, record of executed instructions, indication of next instructions to execute, automatic execution of actions, etc. CPS can provide very useful support to control room operators in their task and contribute, to safer operation of complex plants. Their design and implementation are, however, not trivial tasks. Many factors must be taken into account, not the least the great variance in the environment in which a CPS should be integrated. Other considerations are the requirements to operators in a distributed environment where operators may be located in different geographical areas. A special case of multi-user environment is when different operators cooperate in executing the same procedure. CPSs must also be able to support different Human Computer Interfaces (HCIs) for different operators. Further, they must permit different levels of automation support, and different strategies to execute procedure, like sequential or parallel execution of instructions. In this report requirements, which we consider crucial for design of powerful CPSs, are discussed. The Halden Project has developed a system, COPMA-III, which meets these requirements through providing a core of basic CPS functionalities that can be customised into a target CPS. (Author)

  11. Development of ISA procedure for uranium fuel fabrication and enrichment facilities

    International Nuclear Information System (INIS)

    Yamate, Kazuki; Arakawa, Tomoyuki; Yamashita, Masahiro; Sasaki, Noriaki; Hirano, Mitsumasa

    2011-01-01

    The integrated safety analysis (ISA) procedure has been developed to apply risk-informed regulation to uranium fuel fabrication and enrichment facilities. The major development efforts are as follows: (a) preparing the risk level matrix as an index for items-relied-on-for-safety (IROFS) identification, (b) defining requirements of IROFS, and (c) determining methods of IROFS importance based on the results of risk- and scenario-based analyses. For the risk level matrix, the consequence and likelihood categories have been defined by taking into account the Japanese regulatory laws, rules, and safety standards. The trial analyses using the developed procedure have been performed for several representative processes of the reference uranium fuel fabrication and enrichment facilities. This paper presents the results of the ISA for the sintering process of the reference fabrication facility. The results of the trial analyses have demonstrated the applicability of the procedure to the risk-informed regulation of these facilities. (author)

  12. Recent developments in the UK R5 procedures for assessing high temperature plant

    International Nuclear Information System (INIS)

    Smith, N.G.; Dean, D.W.

    2003-01-01

    Technical programmes of work managed and undertaken by the UK nuclear power generation industry to develop the R5 high temperature assessment procedures have been ongoing for many years. The development programmes are undertaken by British Energy Generation Limited in collaboration with Serco Assurance. The work programmes have largely been driven by the need to advance the methodologies to enable increasingly complex fitness-for-purpose and plant life extension assessments to be undertaken. This is especially true for plant that has been in operation for a number of years where ageing and material degradation issues are prevalent. The R5 procedures are updated on a regular basis, taking into account the information resulting from the development programmes, and other available information world-wide. This paper provides details of the recent advances in the procedures for assessing creep-fatigue initiation and crack growth in high temperature plant. (author)

  13. Documentation for a Structural Optimization Procedure Developed Using the Engineering Analysis Language (EAL)

    Science.gov (United States)

    Martin, Carl J., Jr.

    1996-01-01

    This report describes a structural optimization procedure developed for use with the Engineering Analysis Language (EAL) finite element analysis system. The procedure is written primarily in the EAL command language. Three external processors which are written in FORTRAN generate equivalent stiffnesses and evaluate stress and local buckling constraints for the sections. Several built-up structural sections were coded into the design procedures. These structural sections were selected for use in aircraft design, but are suitable for other applications. Sensitivity calculations use the semi-analytic method, and an extensive effort has been made to increase the execution speed and reduce the storage requirements. There is also an approximate sensitivity update method included which can significantly reduce computational time. The optimization is performed by an implementation of the MINOS V5.4 linear programming routine in a sequential liner programming procedure.

  14. Development of Radioanalytical and Microanalytical Procedures for the Determination of Actinides in Environmental Samples

    Energy Technology Data Exchange (ETDEWEB)

    Macsik, Zsuzsanna [Institute of Nuclear Techniques, Moegyetem rakpart 9, H-1111 Budapest (Hungary); Vajda, Nora [RadAnal Ltd., Bimbo ut 119/a, H-1026 Budapest (Hungary); Bene, Balazs [National Institute of Standards and Technology, Gaithersburg, MD 20899 (United States); Varga, Zsolt [Institute of Isotopes, Konkoly-Thege M. ut 29-33, H-1121 Budapest (Hungary)

    2008-07-01

    A radio-analytical procedure has been developed for the simultaneous determination of actinides in swipe samples by alpha-spectrometry after the separation of the actinides by extraction chromatography. The procedure is based on the complete decomposition of the sample by destruction with microwave digestion or ashing in furnace. Actinides are separated on an extraction chromatographic column filled with TRU resin (product of Eichrom Industries Inc.). Alpha sources prepared from the separated fractions of americium, plutonium, thorium and uranium are counted by alpha spectrometry. Micro-analytical procedure is being developed for the location and identification of individual particles containing fissile material using solid state nuclear track detectors. The parameters of alpha and fission track detection have been optimized and a procedure has been elaborated to locate the particles on the sample by defining the coordinates of the tracks created by the particles on the track detector. Development of a procedure is planned to separate the located particles using micromanipulator and these particles will be examined individually by different micro- and radio-analytical techniques. (authors)

  15. Development of LABGENE's steam generators tube to tubesheet welding qualification procedure

    Energy Technology Data Exchange (ETDEWEB)

    Pozzo, Renato Del [Centro Tecnologico da Marinha em Sao Paulo (CTMSP), Sao Paulo, SP (Brazil)]. E-mail: delpozzo@ctmsp.mar.mil.br; Vieira, Guilherme Godinho [Centro Tecnologico da Marinha em Sao Paulo (CTMSP), SP (Brazil). Centro Experimental ARAMAR; Patineti Filho, Eloi [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)]. E-mail: epatineti@yahoo.com.br

    2007-07-01

    The welding qualification procedure of LABGENE's Nuclear Electric Generation Laboratory - Steam Generators has special characteristics due to nuclear class 1 requirements, reduced dimensions of the LABGENE's equipment and combination of the materials involved with the tube to tubesheet welding. The welding procedure was performed using an automatic orbital welding machine without material addition. The weld joint was simulated using a sample made of a tube (ext. 12,7 BWG 18 x 90 mm) in SB-163 N08800 material and a plate (48 x 330 x 55 mm) in 20MnMoNi55 material, covered with 8 mm AWS E NiCrFe-3 cladding. For the development of the welding procedure, a lot of welding simulations were performed using machines and special devices designed for the dimensions of the pieces. Procedures related with operating, handling and cleaning conditions, essential to avoid the contamination of the pieces were issued. It was also developed a mixture of gases which contributed for the homogenising of the welding and also to avoid the appearance of cracks and defects on the weld joint. The results obtained with the performed tests fulfilled the requirements of the applied specifications and standards. The welding procedure was developed testing a lot of specimens removed from samples that were representatives of the equipment's tube to tubesheet welding. (author)

  16. Development of Visual Field Screening Procedures: A Case Study of the Octopus Perimeter.

    Science.gov (United States)

    Turpin, Andrew; Myers, Jonathan S; McKendrick, Allison M

    2016-05-01

    We develop a methodology for designing perimetric screening procedures, using Octopus perimeters as a case study. The process has three stages: analytically determining specificity and number of presentations required for different multisampling suprathreshold schemes at a single location of the visual field, ranking visual field locations by their positive predictive value (PPV) for glaucoma, and determining a pass/fail criteria for the test. For the case study the Octopus G-program visual field test pattern is used, and a dataset of 385 glaucoma and 86 normal patients. Using a 1-of-3 sampling strategy at a level equal to the 95 percentile of normal observers gave the most robust specificity under the influences of false-negative responses using an average of 1.5 presentations per location. The PPV analysis gave 19 locations that completely classified our glaucomatous data. A further 9 points were added to screen for nonglaucomatous loss. The final stage found that insisting that 3 locations are missed for the screening to fail gave a simulated specificity and sensitivity of approximately 95% for unreliable responders. Our method gives a principled approach to choosing between the many parameters of a visual field screening procedure. We have developed a procedure for the Octopus that should terminate in less than 1 minute for normal observers with high specificity and sensitivity to glaucoma. Visual field screening is used in community settings and eye care practice. This study provides a principled approach to the development of such screening procedures and details a new procedure.

  17. Development of a 3-dimensional flow analysis procedure for axial pump impellers

    International Nuclear Information System (INIS)

    Kim, Min Hwan; Kim, Jong In; Park, Jin Seok; Huh, Houng Huh; Chang, Moon Hee

    1999-06-01

    A fluid dynamic analysis procedure was developed using the three-dimensional solid model of an axial pump impeller which was theoretically designed using I-DEAS CAD/CAM/CAE software. The CFD software FLUENT was used in the flow field analysis. The steady-state flow regime in the MCP impeller and diffuser was simulated using the developed procedure. The results of calculation were analyzed to confirm whether the design requirements were properly implemented in the impeller model. The validity of the developed procedure was demonstrated by comparing the calculation results with the experimental data available. The pump performance at the design point could be effectively predicted using the developed procedure. The computed velocity distributions have shown a good agreement with the experimental data except for the regions near the wall. The computed head, however, was over-predicted than the experiment. The design period and cost required for the development of an axial pump impeller can be significantly reduced by applying the proposed methodology. (author). 7 refs., 2 tabs

  18. EARLY MORAL CONSCIENCE: THE DEVELOPMENT OF A MORAL SHORT PLAYED STORIES PROCEDURE.

    Science.gov (United States)

    Nicolais, Giampaolo; Fazeli-Fariz Hendi, Sara; Modesti, Camilla; Presaghi, Fabio

    2017-05-01

    We set up a cross-sectional study to investigate how moral core self's mental representations develop from age 3 to 6 years. An ad hoc instrument (Moral Short Played Stories Procedure; MSPSP) was developed to tap into how moral emotions, conducts, and cognitions referred to moral and nonmoral characters. A total of 143 preschoolers completed the MSPSP and moral dilemmas procedures, together with attachment and behavioral inhibition assessment. The main results confirm the hypothesis of a mild developmental trend characterized by the prominence of moral conduct over moral emotion and cognition. In addition, our results stress the emergence of a developmental turning point at around age 4 when procedural moral activation in children predicts the declarative feature of moral conscience. © 2017 Michigan Association for Infant Mental Health.

  19. The application of workflow technology in the development of management procedures in NPPs

    International Nuclear Information System (INIS)

    Fang Zhaoxia; Huang Fang

    2012-01-01

    According to the national nuclear safety standards and guides, operating organizations of NPPs should document management programs against all safety related activities. One of the preconditions for the implementation of these programs is to setup a comprehensive instructions and procedures. The workflow technology which is a concept originally from computer technology can help in analysing work processes of different working areas in NPP, designing and developing management procedures hierarchy and requirements. The application of the workflow can not only comprehensively analyse the work process but also analyse the requirements for personnel which are related to the work process, therefore the procedures and programs developed could meet the requirements of national nuclear safety standards and guides. This paper also covers the application of workflow in other areas in NPPs. (authors)

  20. A study on development of the step complexity measure for emergency operating procedures using entropy concepts

    International Nuclear Information System (INIS)

    Park, J. K.; Jung, W. D.; Kim, J. W.; Ha, J. J.

    2001-04-01

    In complex systems, such as nuclear power plants (NPPs) or airplane control systems, human errors play a major role in many accidents. For example, it was reported that about 70% of aviation accidents are due to human errors, and that approximately 28% of accidents in process industries are caused by human errors. According to related studies, written manuals or operating procedures are revealed as one of the most important factors in aviation and manufacturing industries. In case of NPPs, the importance of procedures is more salient than other industries because not only over 50% of human errors were due to procedures but also about 18% of accidents were caused by the failure of following procedures. Thus, the provision of emergency operating procedures (EOPs) that are designed so that the possibility of human errors can be reduced is very important. To accomplish this goal, a quantitative and objective measure that can evaluate EOPs is indispensable. The purpose of this study is the development of a method that can quantify the complexity of a step included in EOPs. In this regard, the step complexity measure (SC) is developed based on three sub-measures such as the SIC (step information complexity), the SLC (step logic complexity) and the SSC (step size complexity). To verify the SC measure, not only quantitative validations (such as comparing SC scores with subjective evaluation results and with averaged step performance time) but also qualitative validations to clarify physical meanings of the SC measure are performed

  1. A study on development of the step complexity measure for emergency operating procedures using entropy concepts

    Energy Technology Data Exchange (ETDEWEB)

    Park, J. K.; Jung, W. D.; Kim, J. W.; Ha, J. J

    2001-04-01

    In complex systems, such as nuclear power plants (NPPs) or airplane control systems, human errors play a major role in many accidents. For example, it was reported that about 70% of aviation accidents are due to human errors, and that approximately 28% of accidents in process industries are caused by human errors. According to related studies, written manuals or operating procedures are revealed as one of the most important factors in aviation and manufacturing industries. In case of NPPs, the importance of procedures is more salient than other industries because not only over 50% of human errors were due to procedures but also about 18% of accidents were caused by the failure of following procedures. Thus, the provision of emergency operating procedures (EOPs) that are designed so that the possibility of human errors can be reduced is very important. To accomplish this goal, a quantitative and objective measure that can evaluate EOPs is indispensable. The purpose of this study is the development of a method that can quantify the complexity of a step included in EOPs. In this regard, the step complexity measure (SC) is developed based on three sub-measures such as the SIC (step information complexity), the SLC (step logic complexity) and the SSC (step size complexity). To verify the SC measure, not only quantitative validations (such as comparing SC scores with subjective evaluation results and with averaged step performance time) but also qualitative validations to clarify physical meanings of the SC measure are performed.

  2. Development and Execution of Autonomous Procedures Onboard the International Space Station to Support the Next Phase of Human Space Exploration

    Science.gov (United States)

    Beisert, Susan; Rodriggs, Michael; Moreno, Francisco; Korth, David; Gibson, Stephen; Lee, Young H.; Eagles, Donald E.

    2013-01-01

    Now that major assembly of the International Space Station (ISS) is complete, NASA's focus has turned to using this high fidelity in-space research testbed to not only advance fundamental science research, but also demonstrate and mature technologies and develop operational concepts that will enable future human exploration missions beyond low Earth orbit. The ISS as a Testbed for Analog Research (ISTAR) project was established to reduce risks for manned missions to exploration destinations by utilizing ISS as a high fidelity micro-g laboratory to demonstrate technologies, operations concepts, and techniques associated with crew autonomous operations. One of these focus areas is the development and execution of ISS Testbed for Analog Research (ISTAR) autonomous flight crew procedures intended to increase crew autonomy that will be required for long duration human exploration missions. Due to increasing communications delays and reduced logistics resupply, autonomous procedures are expected to help reduce crew reliance on the ground flight control team, increase crew performance, and enable the crew to become more subject-matter experts on both the exploration space vehicle systems and the scientific investigation operations that will be conducted on a long duration human space exploration mission. These tests make use of previous or ongoing projects tested in ground analogs such as Research and Technology Studies (RATS) and NASA Extreme Environment Mission Operations (NEEMO). Since the latter half of 2012, selected non-critical ISS systems crew procedures have been used to develop techniques for building ISTAR autonomous procedures, and ISS flight crews have successfully executed them without flight controller involvement. Although the main focus has been preparing for exploration, the ISS has been a beneficiary of this synergistic effort and is considering modifying additional standard ISS procedures that may increase crew efficiency, reduce operational costs, and

  3. Clustering algorithm evaluation and the development of a replacement for procedure 1. [for crop inventories

    Science.gov (United States)

    Lennington, R. K.; Johnson, J. K.

    1979-01-01

    An efficient procedure which clusters data using a completely unsupervised clustering algorithm and then uses labeled pixels to label the resulting clusters or perform a stratified estimate using the clusters as strata is developed. Three clustering algorithms, CLASSY, AMOEBA, and ISOCLS, are compared for efficiency. Three stratified estimation schemes and three labeling schemes are also considered and compared.

  4. A National Survey of Faculty Development Evaluation Outcome Measures and Procedures

    Science.gov (United States)

    Meyer, Katrina A.; Murrell, Vicki S.

    2014-01-01

    This article presents the results of a national study of 39 higher education institutions that collected information about their evaluation procedures and outcome measures for faculty development for online teaching conducted during 2011-2012. The survey results found that over 90% of institutions used measures of the faculty person's…

  5. Next generation of procedural skills curriculum development: Proficiency-based progression

    Directory of Open Access Journals (Sweden)

    Richard M. Satava

    2015-01-01

    Conclusion: The FRS use a new process (full life-cycle curriculum development with proficiency-based progression which can be used in order to develop any quantitative procedural curriculum, through generic templates that have been developed. Such an approach will dramatically decrease the cost, time and effort to develop a new specific curriculum, while producing uniformity in approach, inter-operability among different curricula and consistency in objective assessment. This process is currently online, open source and freely available, to encourage the adoption of a scholarly and rigorous approach to curriculum development which is flexible enough to be adopted and adapted to most technical skills curriculum needs.

  6. Laparoscopy After Previous Laparotomy

    Directory of Open Access Journals (Sweden)

    Zulfo Godinjak

    2006-11-01

    Full Text Available Following the abdominal surgery, extensive adhesions often occur and they can cause difficulties during laparoscopic operations. However, previous laparotomy is not considered to be a contraindication for laparoscopy. The aim of this study is to present that an insertion of Veres needle in the region of umbilicus is a safe method for creating a pneumoperitoneum for laparoscopic operations after previous laparotomy. In the last three years, we have performed 144 laparoscopic operations in patients that previously underwent one or two laparotomies. Pathology of digestive system, genital organs, Cesarean Section or abdominal war injuries were the most common causes of previouslaparotomy. During those operations or during entering into abdominal cavity we have not experienced any complications, while in 7 patients we performed conversion to laparotomy following the diagnostic laparoscopy. In all patients an insertion of Veres needle and trocar insertion in the umbilical region was performed, namely a technique of closed laparoscopy. Not even in one patient adhesions in the region of umbilicus were found, and no abdominal organs were injured.

  7. Conceptual aspects: analyses law, ethical, human, technical, social factors of development ICT, e-learning and intercultural development in different countries setting out the previous new theoretical model and preliminary findings

    NARCIS (Netherlands)

    Kommers, Petrus A.M.; Smyrnova-Trybulska, Eugenia; Morze, Natalia; Issa, Tomayess; Issa, Theodora

    2015-01-01

    This paper, prepared by an international team of authors focuses on the conceptual aspects: analyses law, ethical, human, technical, social factors of ICT development, e-learning and intercultural development in different countries, setting out the previous and new theoretical model and preliminary

  8. SUPPORTING THE INDUSTRY BY DEVELOPING A DESIGN GUIDANCE FOR COMPUTER-BASED PROCEDURES FOR FIELD WORKERS

    Energy Technology Data Exchange (ETDEWEB)

    Oxstrand, Johanna; LeBlanc, Katya

    2017-06-01

    The paper-based procedures currently used for nearly all activities in the commercial nuclear power industry have a long history of ensuring safe operation of the plants. However, there is potential to greatly increase efficiency and safety by improving how the human interacts with the procedures, which can be achieved through the use of computer-based procedures (CBPs). A CBP system offers a vast variety of improvements, such as context driven job aids, integrated human performance tools and dynamic step presentation. As a step toward the goal of improving procedure use performance, the U.S. Department of Energy Light Water Reactor Sustainability Program researchers, together with the nuclear industry, have been investigating the possibility and feasibility of replacing current paper-based procedures with CBPs. The main purpose of the CBP research conducted at the Idaho National Laboratory was to provide design guidance to the nuclear industry to be used by both utilities and vendors. After studying existing design guidance for CBP systems, the researchers concluded that the majority of the existing guidance is intended for control room CBP systems, and does not necessarily address the challenges of designing CBP systems for instructions carried out in the field. Further, the guidance is often presented on a high level, which leaves the designer to interpret what is meant by the guidance and how to specifically implement it. The authors developed a design guidance to provide guidance specifically tailored to instructions that are carried out in the field based.

  9. Development of a radiochemical procedure for certification of phosphorus implantation dose in silicon

    International Nuclear Information System (INIS)

    Paul, R.L.; Simons, D.S.

    2002-01-01

    The U.S. semiconductor industry relies heavily on secondary ion mass spectrometry (SIMS) for characterization of the depth distribution of dopants such as boron, arsenic, and phosphorus in silicon. To assist the industry in achieving high accuracy measurements, two Standard Reference Materials (SRMs) have been developed by NIST as SIMS calibration standards: SRM 2137 (Boron Implant in Silicon), certified by neutron depth profiling, and SRM 2134 (Arsenic Implant in Silicon), certified by instrumental neutron activation analysis. The industry is still in need of a phosphorus standard. Plans are currently underway to develop a phosphorus implant in silicon SRM, to be certified by radiochemical neutron activation analysis (RNAA). RNAA was chosen because other techniques lack the necessary sensitivity, chemical specificity and matrix independence to measure phosphorus at implantation levels. In order to assess the sensitivity, accuracy, and precision of RNAA for this work, preliminary measurements were carried out on six pieces of a phosphorus-implanted silicon wafer that was previously used in a round-robin study of SIMS measurement repeatability. Standards were prepared by depositing micro litre amounts of a standardized phosphorus solution on aluminum foil. A non-implanted silicon wafer was analysed as a blank. Samples were irradiated at a neutron fluency rate of 1 x 10 14 cm -2 s -1 to convert 31 P to 32 P, then mixed with milligram amounts of phosphorus carrier and dissolved in a mixture of nitric and hydrofluoric acids. Phosphorus was separated from the matrix by precipitation first as ammonium phosphomolybdate then as magnesium ammonium phosphate. The yield (fraction of recovered carrier) was determined gravimetrically as Mg(NH 4 )PO 4 .6H 2 O. 32 P was measured using a beta proportional counter. The measurements yielded a mean and standard deviation of (8.35 ± 0.20) x 10 14 atoms.cm -2 (relative standard deviation = 2.35 %), in agreement with both the nominal

  10. Language learning of children with typical development using a deductive metalinguistic procedure.

    Science.gov (United States)

    Finestack, Lizbeth H

    2014-04-01

    PURPOSE In the current study, the author aimed to determine whether 4- to 6-year-old typically developing children possess requisite problem-solving and language abilities to produce, generalize, and retain a novel verb inflection when taught using an explicit, deductive teaching procedure. METHOD Study participants included a cross-sectional sample of 4-, 5-, and 6-year-old children with typical cognitive and language development. The 66 participants were randomly assigned to either a deductive or inductive teaching condition in which they were taught a novel gender morphological inflection across 4 sessions. Learning was assessed on the basis of performance on learning, generalization, and maintenance probes. RESULTS Across all age groups, children were more likely to successfully use the novel gender form when taught using the deductive procedure than if taught using the inductive procedure (Φ range: .33-.73). Analyses within each age group revealed a robust effect for the 5-year-old children, with less consistent effects across the other age groups. CONCLUSIONS Study results suggest that 4- to 6-year-old children with typical language and cognitive abilities are able to make use of a deductive language teaching procedure when learning a novel gender inflection. Evidence also suggests that this effect is driven by expressive and receptive language ability.

  11. Development of intra-strain self-cloning procedure for breeding baker's yeast strains.

    Science.gov (United States)

    Nakagawa, Youji; Ogihara, Hiroyuki; Mochizuki, Chisato; Yamamura, Hideki; Iimura, Yuzuru; Hayakawa, Masayuki

    2017-03-01

    Previously reported self-cloning procedures for breeding of industrial yeast strains require DNA from other strains, plasmid DNA, or mutagenesis. Therefore, we aimed to construct a self-cloning baker's yeast strain that exhibits freeze tolerance via an improved self-cloning procedure. We first disrupted the URA3 gene of a prototrophic baker's yeast strain without the use of any marker gene, resulting in a Δura3 homozygous disruptant. Then, the URA3 gene of the parental baker's yeast strain was used as a selection marker to introduce the constitutive TDH3 promoter upstream of the PDE2 gene encoding high-affinity cyclic AMP phosphodiesterase. This self-cloning procedure was performed without using DNA from other Saccharomyces cerevisiae strains, plasmid DNA, or mutagenesis and was therefore designated an intra-strain self-cloning procedure. Using this self-cloning procedure, we succeeded in producing self-cloning baker's yeast strains that harbor the TDH3p-PDE2 gene heterozygously and homozygously, designated TDH3p-PDE2 hetero and TDH3p-PDE2 homo strains, respectively. These self-cloning strains expressed much higher levels of PDE2 mRNA than the parental strain and exhibited higher viability after freeze stress, as well as higher fermentation ability in frozen dough, when compared with the parental strain. The TDH3p-PDE2 homo strain was genetically more stable than the TDH3p-PDE2 hetero strain. These results indicate that both heterozygous and homozygous strains of self-cloning PDE2-overexpressing freeze-tolerant strains of industrial baker's yeast can be prepared using the intra-strain self-cloning procedure, and, from a practical viewpoint, the TDH3p-PDE2 homo strain constructed in this study is preferable to the TDH3p-PDE2 hetero strain for frozen dough baking. Copyright © 2016 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

  12. Development of Irradiation Procedure for Gamma Irradiation Chamber Bio beam GM 8000

    International Nuclear Information System (INIS)

    Shuhaimi Shamsudin; Affrida Abu Hassan; Zaiton Ahmad; Abdul Rahim Harun; Ahmad Zainuri Mohd Dzomir

    2015-01-01

    Bio Beam GM 8000 gamma irradiation chamber obtained a conditional approval to operate on March 27, 2012, and later acquired a full approval on December 13, 2012. The objective for the procurement of this gamma chamber is to develop an acute irradiation facility for biological samples, including plants tissues, insects, pupae, microorganisms, as well as animal and human cells. To ensure a smooth and efficient operation, irradiation procedures were developed and improved over time. This paper discusses the operation and management of the Bio Beam GM 8000 facility, including irradiation procedures and sample preparation, application for services through online e-client system, consultancy, quality assurance and information dissemination to internal as well as external clients. In addition, this paper also discusses the potential, constraints and improvement measures taken to optimize the use of this facility in order to meet its objectives. (author)

  13. Developing Procedures to Improve Therapist-Child Rapport in Early Intervention.

    Science.gov (United States)

    Lugo, Ashley M; King, Melissa L; Lamphere, John C; McArdle, Paige E

    2017-12-01

    Rapport is a primary component in the development of a therapeutic relationship between health-service professionals and clients. Presession pairing is a procedure often recommended in behavior analytic practice to build rapport with clients. However, many service providers may not exhibit presession pairing skills correctly or at a sufficient rate. The current study aimed to operationally define therapist behaviors that are indicative of presession pairing and to train direct care staff to implement said skills.

  14. Development of Visual Field Screening Procedures: A Case Study of the Octopus Perimeter

    OpenAIRE

    Turpin, Andrew; Myers, Jonathan S.; McKendrick, Allison M.

    2016-01-01

    Purpose We develop a methodology for designing perimetric screening procedures, using Octopus perimeters as a case study. Methods The process has three stages: analytically determining specificity and number of presentations required for different multisampling suprathreshold schemes at a single location of the visual field, ranking visual field locations by their positive predictive value (PPV) for glaucoma, and determining a pass/fail criteria for the test. For the case study the Octopus G-...

  15. Development of a radiochemical neutron activation analysis procedure for determination of rhenium in biological and environmental samples at ultratrace level

    International Nuclear Information System (INIS)

    Kucera, J.; Lucanikova, M.; Czech Technical Univ., Prague

    2006-01-01

    Radiochemical neutron activation procedures using liquid-liquid extraction with tetraphenylarsonium chloride in chloroform from 1M HCl and solid extraction with ALIQUAT 336 incorporated in a polyacrylonitrile binding matrix from 0.1M HCl were developed for accurate determination of rhenium in biological and environmental samples at the sub-ng x g -1 level. Concentrations of Re in the range of 0.1 to 2.4 ng x g -1 were determined in several botanical reference materials (RM), while in a RM of road dust a value of ∼ 10 ng x g -1 was found. Significantly elevated values of Re, up to 90 ng x g -1 were found in seaweed (brown algae). Results for Re in the brown algae Fucus vesiculosus in which elevated 99 Tc values had previously been determined suggested possible competition between Re and Tc in the accumulation process. (author)

  16. Development of Coring Procedures Applied to Si, CdTe, and CIGS Solar Panels

    Energy Technology Data Exchange (ETDEWEB)

    Moutinho, Helio R [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Johnston, Steven [National Renewable Energy Laboratory (NREL), Golden, CO (United States); To, Bobby [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Jiang, Chun Sheng [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Xiao, Chuanxiao [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Hacke, Peter L [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Moseley, John [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Tynan, Gerald D [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Al-Jassim, Mowafak M [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Dhere, N. G. [Florida Solar Energy Center

    2018-01-04

    Most of the research on the performance and degradation of photovoltaic modules is based on macroscale measurements of device parameters such as efficiency, fill factor, open-circuit voltage, and short-circuit current. Our goal is to develop the capabilities to allow us to study the degradation of these parameters in the micro- and nanometer scale and to relate our results to performance parameters. To achieve this objective, the first step is to be able to access small samples from specific areas of the solar panels without changing the properties of the material. In this paper, we describe two coring procedures that we developed and applied to Si, CIGS, and CdTe solar panels. In the first procedure, we cored full samples, whereas in the second we performed a partial coring that keeps the tempered glass intact. The cored samples were analyzed by different analytical techniques before and after coring, at the same locations, and no damage during the coring procedure was observed.

  17. Analytical quality assurance procedures developed for the IAEA's Reference Asian Man Project (Phase 2)

    International Nuclear Information System (INIS)

    Kawamura, H.; Parr, R.M.; Dang, H.S.; Tian, W.; Barnes, R.M.; Iyengar, G.V.

    2000-01-01

    Analytical quality assurance procedures adopted for use in the IAEA Co-ordinated Research Project on Ingestion and Organ Content of Trace Elements of Importance in Radiological Protection are designed to ensure comparability of the analytical results for Cs, I, Sr, Th, U and other elements in human tissues and diets collected and analysed in nine participating countries. The main analytical techniques are NAA and ICP-MS. For sample preparation, all participants are using identical food blenders which have been centrally supplied after testing for contamination. For quality control of the analyses, six NIST SRMs covering a range of matrices with certified and reference values for the elements of interest have been distributed. A new Japanese reference diet material has also been developed. These quality assurance procedures are summarized here and new data are presented for Cs, I, Sr, Th and U in the NIST SRMs. (author)

  18. Procedure development study: Low strain rate and creep experiments; Yucca Mountain Site Characterization Project

    Energy Technology Data Exchange (ETDEWEB)

    Martin, R.J. III; Boyd, P.J.; Noel, J.S. [New England Research, Inc., White River Junction, VT (United States); Price, R.H. [Sandia National Labs., Albuquerque, NM (United States)

    1991-10-01

    Licensing of the potential nuclear-waste repository at Yucca Mountain by the Nuclear Regulatory Commission would require, among other things, demonstrations of the long term usability of the underground facilities. Such a demonstration involves analysis of the mechanical response of the rock to the presence of underground openings and heat-producing waste, which in turn requires data on the mechanical properties of the rock. This document describes the experimental results from a scoping study which led to the development of procedures for performing quality-affecting rock-mechanics experiments on intact rock. The future experiments performed with these procedures will produce information on the time-dependent deformation of welded tuff and represent one aspect of the overall effort to characterize the rheology of the rock mass. 3 refs., 42 figs., 6 tabs.

  19. Development of manual procedures for care of pregnant patients in radiotherapy service

    International Nuclear Information System (INIS)

    Scarabino, M.L.; Ruggeri, R.M.; Colombo, S.; Mairal, L.; Sardi, M.E.

    2013-01-01

    The work involves the creation of a manual of procedures for the care of pregnant patients in a radiotherapy center in which each instance of treatment is included, from the obstetrician-oncology comprehensive assessment during admission to establishing controls newborn and its subsequent development in multidisciplinary team. For the preparation of the manual had to design an anthropomorphic phantom that resembles a pregnant woman, which was used to carry out internal and external dosimetry. In turn imparted calculations fetal doses using TPS, imaging tests with MRI, avoiding the use of the tomograph and adapted to the resonator involved were carried immobilizer. All experiences and progress made during the treated cases are introduced in the procedures manual, making it a dynamic tool for continuous improvement for the institution

  20. The development of a quantitative measure for the complexity of emergency tasks stipulated in emergency operating procedures of nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jin Kyun; Jung, Won Dea

    2006-11-15

    Previous studies have continuously pointed out that human performance is a decisive factor affecting the safety of complicated process systems. Subsequently, as the result of extensive efforts, it has been revealed that the provision of procedures is one of the most effective countermeasures, especially if human operators have to carry out their tasks under a very stressful environment. That is, since good procedures are helpful to not only enhance the performance of human operators but also the reduction of the possibility of a human error through stipulating detailed tasks to be done by human operators. Ironically, it has been emphasized that the performance of human operators could be impaired due to complicated procedures, because procedures directly govern the physical as well as cognitive behavior of human operators by institutionalizing detailed actions. Therefore, it is a prerequisite to develop a systematic framework that properly evaluate the complexity of tasks described in procedures. For this reason, a measure called TACOM (Task Complexity) that can quantify the complexity of emergency tasks described in the emergency operating procedures (EOPs) of NPPs has been developed. In this report, a technical background as well as practical steps to quantify the complexity of tasks were presented with a series of studies that were conducted to ensure the validity of the TACOM measure. As a result of validation studies, since it is shown that the TACOM measure seem to properly quantify the complexity of emergency tasks, it is desirable that the TACOM measure plays an important role in improving the performance of human operators.

  1. The development of a quantitative measure for the complexity of emergency tasks stipulated in emergency operating procedures of nuclear power plants

    International Nuclear Information System (INIS)

    Park, Jin Kyun; Jung, Won Dea

    2006-11-01

    Previous studies have continuously pointed out that human performance is a decisive factor affecting the safety of complicated process systems. Subsequently, as the result of extensive efforts, it has been revealed that the provision of procedures is one of the most effective countermeasures, especially if human operators have to carry out their tasks under a very stressful environment. That is, since good procedures are helpful to not only enhance the performance of human operators but also the reduction of the possibility of a human error through stipulating detailed tasks to be done by human operators. Ironically, it has been emphasized that the performance of human operators could be impaired due to complicated procedures, because procedures directly govern the physical as well as cognitive behavior of human operators by institutionalizing detailed actions. Therefore, it is a prerequisite to develop a systematic framework that properly evaluate the complexity of tasks described in procedures. For this reason, a measure called TACOM (Task Complexity) that can quantify the complexity of emergency tasks described in the emergency operating procedures (EOPs) of NPPs has been developed. In this report, a technical background as well as practical steps to quantify the complexity of tasks were presented with a series of studies that were conducted to ensure the validity of the TACOM measure. As a result of validation studies, since it is shown that the TACOM measure seem to properly quantify the complexity of emergency tasks, it is desirable that the TACOM measure plays an important role in improving the performance of human operators

  2. The development and work procedures to super speed network for the growing demands for the network

    International Nuclear Information System (INIS)

    Nosaki, Nobuhisa; Aoki, Kazuhisa

    2001-01-01

    Following the recently growing demands for the network, the modification of Local Area Network (LAN) and Wide Area Network (WAN) to super speed network have been reviewed in the Japan Nuclear Cycle Development Institute (JNC). Though the modification of the LAN to super speed network is being developed this year in Heisei 13 fiscal year, it of the WAN was developed in Heisei 12 fiscal year. In spite of various issues, technical reviews and etc., there are a lot of benefits and merit for the super speed network of the WAN and though the modification of it and reduction of the running cost are contradictory to each other, both of those have been achieved in the JNC. This paper introduces the development and work procedures for the WAN. (author)

  3. A case of cutaneous squamous cell carcinoma associated with small cell carcinoma of lung developing a skin metastasis on previously irradiated area

    International Nuclear Information System (INIS)

    Kohda, Mamoru; Takei, Yoji; Ueki, Hiroaki

    1983-01-01

    Squamous cell carcinoma which occurred in the penis of a 61-year-old male patient was treated surgically and by Linac (a total of 10,400 rad). However, it was not cured. Abnormal shadows in the lung and multiple liver tumor was noted one month before death. Autopsy revealed generalized metastases of pulmonary small-cell carcinoma, and persistent squamous cell carcinoma of the penis with no metastases. Skin metastasis of lung carcinoma occurred only in the area previously irradiated. (Ueda, J.)

  4. Assessment of Competence in EVAR Procedures: A Novel Rating Scale Developed by the Delphi Technique.

    Science.gov (United States)

    Strøm, M; Lönn, L; Bech, B; Schroeder, T V; Konge, L

    2017-07-01

    To develop a procedure specific global rating scale for assessment of operator competence in endovascular aortic repair (EVAR). A Delphi approach was used to achieve expert consensus. A panel of 32 international experts (median 300 EVAR procedures, range 200-3000) from vascular surgery (n = 21) and radiology (n = 11) was established. The first Delphi round was based on a review of endovascular skills assessment papers, stent graft instructions for use, and structured interviews. It led to a primary pool of 83 items that were formulated as global rating scale items with tentative anchors. Iterative Delphi rounds were executed. The panellists rated the importance of each item on a 5 point Likert scale. Consensus was defined as 80% of the panel rating an item 4 or 5 in the primary round and 90% in subsequent rounds. Consensus on the final assessment tool was defined as Cronbach's alpha > .8 after a minimum of three rounds. Thirty-two of 35 invited experts participated. Three rounds of surveys were completed with a completion rate of 100% in the first two rounds and 91% in round three. The 83 primary assessment items were supplemented with five items suggested by the panel and reduced to seven pivotal assessment items that reached consensus, Cronbach's alpha = 0.82. The seven item rating scale covers key elements of competence in EVAR stent placement and deployment. Each item has well defined grades with explicit anchors at unacceptable, acceptable, and superior performance on a 5 point Likert scale. The Delphi methodology allowed for international consensus on a new procedure specific global rating scale for assessment of competence in EVAR. The resulting scale, EndoVascular Aortic Repair Assessment of Technical Expertise (EVARATE), represents key elements in the procedure. EVARATE constitutes an assessment tool for providing structured feedback to endovascular operators in training. Copyright © 2017 European Society for Vascular Surgery. Published by Elsevier

  5. Development of regulatory procedures for the disposal of solid radioactive waste in deep, continental formations

    International Nuclear Information System (INIS)

    1980-01-01

    For the disposal of radioactive waste, and in particular, of the high-level and alpha-bearing waste from the nuclear fuel cycle, the most favoured solution in most countries is disposal in deep, continental geological formations. Commitment to this disposal method involves a number of issues related to the various stages of the disposal programme which must be addressed through some reasoned decision-making process. Most countries are opting for regulating such a programme through licensing actions by a body whose purpose is to review, certify and ensure the safety of all the stages of the disposal programme. This regulatory body may either be one single national authority or a system of authorities designated by the government. The key to such regulation is the set of procedures, determined in advance, for the actions of the implementing organization, the review by the regulatory body and the involvement of other parties. This document concerns itself with the procedures which could logically be followed in reaching a set of rational decisions by the regulatory body. Care in the preparation and application of such procedures is an important element in the acceptability of the concept, the site and the other aspects of the disposal programme. The intention of this document is to give guidance as to what issues should be addressed in the licensing review, what decision points are important, and what guidance should be given to the applicant by the regulatory body in the course of the licensing actions. The procedures are keyed to be designed according to the logical steps involved in the development and operation of the repository. However, the document does not pretend to give guidance regarding the optimal interactions between the implementing organization and the regulatory body. This document is oriented to the disposal of solid radioactive waste in deep, continental geological formations using mining techniques

  6. Development of a green procedure of citrus fruits waste processing to recover carotenoids

    OpenAIRE

    Meryem Boukroufa; Chahrazed Boutekedjiret; Farid Chemat

    2017-01-01

    In this study, an original and green procedure of processing waste of the citrus fruits was developed using the concept of bio-refinery, innovative techniques “ultrasound” and “micro-wave”, and a green solvent “limonene” to recover carotenoids. Essential oil extraction was performed by Solvent Free Microwave Extraction (SFME) and compared to steam distillation (SD). The essential oil yields were comparable for both processes: 4.02 ± 0.23% for SFME and 4.16 ± 0.05% for SD. After that, caroteno...

  7. Developing Characterization Procedures for Qualifying both Novel Selective Laser Sintering Polymer Powders and Recycled Powders

    Energy Technology Data Exchange (ETDEWEB)

    Bajric, Sendin [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-09-12

    Selective laser sintering (SLS) is an additive technique which is showing great promise over conventional manufacturing techniques. SLS requires certain key material properties for a polymer powder to be successfully processed into an end-use part, and therefore limited selection of materials are available. Furthermore, there has been evidence of a powder’s quality deteriorating following each SLS processing cycle. The current investigation serves to build a path forward in identifying new SLS powder materials by developing characterization procedures for identifying key material properties as well as for detecting changes in a powder’s quality. Thermogravimetric analyses, differential scanning calorimetry, and bulk density measurements were investigated.

  8. Report on nuclear industry quality assurance procedures for safety analysis computer code development and use

    International Nuclear Information System (INIS)

    Sheron, B.W.; Rosztoczy, Z.R.

    1980-08-01

    As a result of a request from Commissioner V. Gilinsky to investigate in detail the causes of an error discovered in a vendor Emergency Core Cooling System (ECCS) computer code in March, 1978, the staff undertook an extensive investigation of the vendor quality assurance practices applied to safety analysis computer code development and use. This investigation included inspections of code development and use practices of the four major Light Water Reactor Nuclear Steam Supply System vendors and a major reload fuel supplier. The conclusion reached by the staff as a result of the investigation is that vendor practices for code development and use are basically sound. A number of areas were identified, however, where improvements to existing vendor procedures should be made. In addition, the investigation also addressed the quality assurance (QA) review and inspection process for computer codes and identified areas for improvement

  9. Procedure of Improvement of the Marketing Mechanism of Introduction of Innovation Developments

    Directory of Open Access Journals (Sweden)

    Tsapuk Olena Yu.

    2014-01-01

    Full Text Available The article considers the modern state of the power industry and its place in the Ukrainian economy as a basis of sustainable development and competitiveness of the country with consideration of high power intensity of the national gross domestic product. It analyses barriers on the way to increase of power efficiency of the country and pays special attention to the mechanism of implementation of innovation developments and also role of investment and innovation components of programmes of power saving and development of the Ukrainian power industry. It reviews modern scientific approaches to interpretation of the “marketing mechanism” notion, considers essence of the mechanism of implementation of innovation developments in the context of interconnection with marketing and offers a new definition of the marketing mechanism of implementation of innovation developments. It offers and justifies the procedure of improvement of the marketing mechanism of implementation of innovation developments, which takes into account key determinants of external and internal environments, is based on the use of economic and mathematical methods, which allow forecasting behaviour of an industrial consumer, identification of measures on improvement of the organisational and economic provision of implementation of innovation developments and increase of competitiveness of power engineering enterprises.

  10. Development Procedure in Mutation Induction and Tracer Technique for Good Agriculture Practices for Under used Crops

    International Nuclear Information System (INIS)

    Faiz Ahmad; Rusli Ibrahim; Khairuddin Abdul Rahim

    2015-01-01

    Under used crops are those crop species which have high potential value in the supply of important raw material for secondary economy sector in food processing. The yield production of new Under used crops varieties can be used as an important input in food production process for export products. The optimum production cost can be minimized since the price of raw material supplied from agriculture sector is cheaper compared with the international markets. Agriculture output can be increased through the development of Under used crops using radiation mutagenesis and tracer technique for good agricultural practices. This paper work will discuss the development procedure of mutation induction method which includes irradiation of samples such as seeds of groundnut and in vitro shoots of banana using gamma rays and application of N-15 for nutrient use efficiency and screening of potential mutant lines with high yield and resistance to drought. These management practices using established procedures of water and nutrient use efficiency will be recommended to the growers. (author)

  11. Developing standard performance testing procedures for MC and A components at a site

    International Nuclear Information System (INIS)

    Scherer, Carolynn

    2010-01-01

    The condition of a nuclear material control and accountability system (MC and A) and its individual components, as with any system combining technical elements, documentation and the human factor, may be characterized through an aggregate of values for the various parameters that determine the system's ability to perform. The MC and A system's status may be functioning effectively, marginally or not functioning based on a summary of the values of the individual parameters. This work included a review of the following elements and subsystems or components for a material control and accountability system: (1) MC and A Elements: Information subsystem, Measurement subsystem, NM access subsystem, including a tamper-indicating device (TID) program, and Automated information-gathering subsystem; and (2) Detecting NM Loses Elements: Inventory differences, Shipper/receiver differences, Confirmatory measurements and differences with accounting data, and TID or seal violations. In order to detect the absence or loss of nuclear material there must be appropriate interactions among the elements and their respective subsystems (from the list above). Additionally this work includes a review of the status of regulatory requirements for the MC and A system components and potential criteria that support the evaluation of the performance of the listed components. The listed components had performance testing algorithms and procedures developed that took into consideration the regulatory criteria. The developed MC and A performance-testing procedures were the basis for a pilot Guide for MC and A Performance Testing at the MBAs of SSC RF IPPE.

  12. Development of procedure for emergency response in the case of combined disaster

    International Nuclear Information System (INIS)

    2012-01-01

    It has been discussed that there were many differences to international standards and the delay for prior planning implementation of nuclear emergency preparedness. Based on this points, since fiscal year 2011, the framework for execution of the precautionary action etc. in consideration of the international standard to the Guide 'Emergency Preparedness for Nuclear Facilities' has been implemented by NSC (Nuclear Safety Commission) of Japan. On the other hand, it was clarified that there would be many problems for decision making strategies of protective actions at the nuclear disaster (combined disaster) when the natural disasters such as earthquakes and tsunamis, the flood, the heavy snow, and the large-scale fire, etc. occurred, and implementation of criteria and procedure for protective action execution through the experience with protective actions after the East Japan large-scale earthquake. The problem arrangements and data preparations to develop the emergency protective action procedure for the emergency preparedness manuals corresponding to the combined disasters are scheduled to be executed in this study for three years from the fiscal year 2011 based on the experience and the finding in the East Japan large-scale earthquake. Development and verification of the method of Evacuation Time Estimate (ETE) at the combined disaster are executed in this year. (author)

  13. Development of Computational Procedure for Assessment of Patient Dose in Multi-Detector Computed Tomography

    International Nuclear Information System (INIS)

    Park, Dong Wook

    2007-02-01

    Technological development to improve the quality and speed with which images are obtained have fostered the growth of frequency and collective effective dose of CT examination. Especially, High-dose x-ray technique of CT has increased in the concern of patient dose. However CTDI and DLP in CT dosimetry leaves something to be desired to evaluate patient dose. And even though the evaluation of effective dose in CT practice is required for comparison with other radiography, it's not sufficient to show any estimation because it's not for medical purpose. Therefore the calculation of effective dose in CT procedure is needed for that purpose. However modelling uncertainties will be due to insufficient information from manufacturing tolerances. Therefore the purpose of this work is development of computational procedure for assessment of patient dose through the experiment for getting essential information in MDCT. In order to obtain exact absorbed dose, normalization factors must be created to relate simulated dose values with CTDI air measurement. The normalization factors applied to the calculation of CTDI 100 using axial scanning and organ effective dose using helical scanning. The calculation of helical scanning was compared with the experiment of Groves et al.(2004). The result has a about factor 2 of the experiment. It seems because AEC is not simulated. In several studies, when AEC applied to a CT examination, approximately 20-30% dose reduction was appeared. Therefore the study of AEC simulation should be added and modified

  14. Establishment of a Molding Procedure to Facilitate Formulation Development for Co-extrudates.

    Science.gov (United States)

    Eder, Simone; Beretta, Michela; Witschnigg, Andreas; Koutsamanis, Ioannis; Eggenreich, Karin; Khinast, Johannes G; Koscher, Gerold; Paudel, Amrit; Nickisch, Klaus; Friedrich, Maika; Froehlich, Eleonore; Roblegg, Eva

    2017-11-01

    Co-extrusion offers a number of advantages over conventional manufacturing techniques. However, the setup of a co-extrusion line is cost- and time-intense and formulation development is challenging. This work introduces a novel procedure to test the applicability of a co-extruded reservoir-type system at an early product development stage. We propose vacuum compression molding (VCM), a fast procedure that requires only small material amounts, for the manufacturing of cylindrical reservoir-type system. To this end, the commercially available co-extruded product NuvaRing ® and variations thereof were used as test systems. All VCM systems showed a homogeneous skin thickness that adhered well to the core, thereby providing a precise core/skin interface. As drug release is a key criterion for pharmaceutical products, a modified in vitro dissolution method was set up to test the VCM systems. The drug release from the VCM systems was in the same order of magnitude as the corresponding co-extruded strands and followed the same release kinetics. Moreover, the VCM systems were capable of indicating the relative effect of formulation-related modifications on drug release. Overall, this shows that this system is a powerful tool that facilitates formulation tailoring and co-extrusion process setup at the earliest stage.

  15. Probabilistic safety evaluation: Development of procedures with applications on components used in nuclear power plants

    International Nuclear Information System (INIS)

    Dillstroem, P.

    2000-12-01

    A probabilistic procedure has been developed by SAQ Kontroll AB to calculate two different failure probabilities, P F : Probability of failure, defect size given by NDT/NDE. Probability of failure, defect not detected by NDT/NDE. Based on the procedure, SAQ Kontroll AB has developed a computer program PROPSE (PRObabilistic Program for Safety Evaluation). Within PROPSE, the following features are implemented: Two different algorithms to calculate the probability of failure are included: Simple Monte Carlo Simulation (MCS), with an error estimate on P F . First-Order Reliability Method (FORM), with sensitivity factors using the most probable point of failure in a standard normal space. Using these factors, it is possible to rank the parameters within an analysis. Estimation of partial safety factors, given an input target failure probability and characteristic values for fracture toughness, yield strength, tensile strength and defect depth. Extensive validation has been carried out, using the probabilistic computer program STAR6 from Nuclear Electric and the deterministic program SACC from SAQ Kontroll AB. The validation showed that the results from PROPSE were correct, and that the algorithms used in STAR6 were not intended to work for a general problem, when the standard deviation is either 'small' or 'large'. Distributions, to be used in a probabilistic analysis, are discussed. Examples on data to be used are also given

  16. Development of design procedures for fast reactors in the United Kingdom

    International Nuclear Information System (INIS)

    Rose, R.T.; Tomkins, B.; Townley, C.H.A.

    1989-01-01

    A considerable amount of research has been carried out in the United Kingdom during the past two decades to quantify the factors which control the integrity of structural components. The work which has been aimed at understanding the performance of structures at high temperature, is particularly relevant to the Fast Reactor. At the same time, because of the need to demonstrate the tolerance to defects in the low temperature as well as the high temperature components, defect assessment criteria are also of great importance. Emphasis is now being given to the development of design procedures specifically for Fast Reactors, making use of the research so far completed. The United Kingdom proposals are being integrated with those from France, Federal Republic of Germany and Italy as part of the European collaborative venture. The paper outlines the major developments which are currently in hand, and brings up to date the review of United Kingdom activities presented at Tokyo in 1986. (author)

  17. Development of a procedure for evaluating the economics of process options in commercial HTGR fuel cycle

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, W.E.

    1976-05-01

    The report presented describes the status of and calculational procedures used in a machine code being developed for calculating costs of fresh fuel fabrication, chemical reprocessing, and refabrication of HTGR fuel. In its present state of development, the capability is confined principally to calculating annual mainstream and scrap recovery process throughputs in fresh fuel fabrication, chemical reprocessing, and refabrication. The code works from user-supplied reactor build schedules and fuel specifications to approximate changing fuel fabrication requirements over a 20-year (maximum) projection. The availability of a reprocessing facility may be delayed to some specified date beyond the first year of a projection. Some of the cost routines have also been programmed and are described.

  18. Development of procedure using plasma welding process to produce 125I seeds

    International Nuclear Information System (INIS)

    Feher, Anselmo

    2006-01-01

    The prostate cancer, which is the second cause of death by cancer in men, overcome only by lung cancer, is a problem of public health in Brazil. Brachytherapy is among the possible available treatments for prostate cancer, in which small seeds containing 125 I radioisotope are implanted in the prostate. The seed consists of a titanium sealed capsule with 0.8 mm external diameter and 4.5 mm length, containing a central silver wire with adsorbed 125 I. The plasma arc welding is one of the viable techniques for the sealing process. The equipment used in this technique is less costly than in other processes. The main objective of this work was the development and the validation of the welding procedure using plasma welding process and the elaboration of a sealing routine according to Good Manufacturing Practices. The development of this work has presented the following phases: cut and cleaning of the titanium material, determination of the welding parameters, development of a device for holding the titanium tube during the welding process, validation of sealed sources according to ISO 2919 Sealed Radioactive Sources - General Requirements and Classification, leakage test according to ISO 9978 Sealed Radioactive Sources - Leakage Test Methods and metallographic assays. The developed procedure, to seal 125 I seeds using plasma welding process, has shown to be efficient, satisfying all the established requirements of ISO 2919. The results obtained in this work have given the possibility to establish a routine production process according to the orientations presented in resolution RDC number 59 - Good Manufacturing Practices do Medical Products of the ANVISA - Brazilian Nacional Agency of Sanitary Surveillance. (author)

  19. Development of a digital impression procedure using photogrammetry for complete denture fabrication.

    Science.gov (United States)

    Matsuda, Takashi; Goto, Takaharu; Kurahashi, Kosuke; Kashiwabara, Toshiya; Ichikawa, Tetsuo

    We developed an innovative procedure for digitizing maxillary edentulous residual ridges with a photogrammetric system capable of estimating three-dimensional (3D) digital forms from multiple two-dimensional (2D) digital images. The aim of this study was to validate the effectiveness of the photogrammetric system. Impressions of the maxillary residual ridges of five edentulous patients were taken with four kinds of procedures: three conventional impression procedures and the photogrammetric system. Plaster models were fabricated from conventional impressions and digitized with a 3D scanner. Two 3D forms out of four forms were superimposed with 3D inspection software, and differences were evaluated using a least squares best fit algorithm. The in vitro experiment suggested that better imaging conditions were in the horizontal range of ± 15 degrees and at a vertical angle of 45 degrees. The mean difference between the photogrammetric image (Form A) and the image taken from conventional preliminarily impression (Form C) was 0.52 ± 0.22 mm. The mean difference between the image taken of final impression through a special tray (Form B) and Form C was 0.26 ± 0.06 mm. The mean difference between the image taken from conventional final impression (Form D) and Form C was 0.25 ± 0.07 mm. The difference between Forms A and C was significantly larger than the differences between Forms B and C and between Forms D and C. The results of this study suggest that obtaining digital impressions of edentulous residual ridges using a photogrammetric system is feasible and available for clinical use.

  20. Development of Probabilistic Performance Evaluation Procedure for Umbilical Lines of Seismically Isolated NPPs

    International Nuclear Information System (INIS)

    Hahm, Daegi; Park, Junhee; Choi, Inkil

    2013-01-01

    In this study, we proposed a procedure to perform the probabilistic performance evaluation of interface piping system for seismically isolated NPPs, and carried out the preliminary performance evaluation of the target example umbilical line. For EDB level earthquakes, the target performance goal cannot be fulfilled, but we also find out that the result can be changed with respect to the variation of the assumed values, i. e., the distribution of response, and the limit state of piping system. Recently, to design the nuclear power plants (NPPs) more efficiently and safely against the strong seismic load, many researchers focus on the seismic isolation system. For the adoption of seismic isolation system to the NPPs, the seismic performance of isolation devices, structures, and components should be guaranteed firstly. Hence, some researches were performed to determine the seismic performance of such items. For the interface piping system between isolated structure and non-isolated structure, the seismic capacity should be carefully estimated since that the required displacement absorption capacity will be increased significantly by the adoption of the seismic isolation system. Nowadays, in NUREG report, the probabilistic performance criteria for isolated NPP structures and components are proposed. Hence, in this study, we developed the probabilistic performance evaluation method and procedure for interface piping system, and applied the method to an example pipe. The detailed procedure and main results are summarized in next section. For the interface piping system, the seismic capacity should be carefully estimated since that the required displacement absorption capacity will be increased significantly by the adoption of the seismic isolation system

  1. Developing a spatial-statistical model and map of historical malaria prevalence in Botswana using a staged variable selection procedure

    Directory of Open Access Journals (Sweden)

    Mabaso Musawenkosi LH

    2007-09-01

    Full Text Available Abstract Background Several malaria risk maps have been developed in recent years, many from the prevalence of infection data collated by the MARA (Mapping Malaria Risk in Africa project, and using various environmental data sets as predictors. Variable selection is a major obstacle due to analytical problems caused by over-fitting, confounding and non-independence in the data. Testing and comparing every combination of explanatory variables in a Bayesian spatial framework remains unfeasible for most researchers. The aim of this study was to develop a malaria risk map using a systematic and practicable variable selection process for spatial analysis and mapping of historical malaria risk in Botswana. Results Of 50 potential explanatory variables from eight environmental data themes, 42 were significantly associated with malaria prevalence in univariate logistic regression and were ranked by the Akaike Information Criterion. Those correlated with higher-ranking relatives of the same environmental theme, were temporarily excluded. The remaining 14 candidates were ranked by selection frequency after running automated step-wise selection procedures on 1000 bootstrap samples drawn from the data. A non-spatial multiple-variable model was developed through step-wise inclusion in order of selection frequency. Previously excluded variables were then re-evaluated for inclusion, using further step-wise bootstrap procedures, resulting in the exclusion of another variable. Finally a Bayesian geo-statistical model using Markov Chain Monte Carlo simulation was fitted to the data, resulting in a final model of three predictor variables, namely summer rainfall, mean annual temperature and altitude. Each was independently and significantly associated with malaria prevalence after allowing for spatial correlation. This model was used to predict malaria prevalence at unobserved locations, producing a smooth risk map for the whole country. Conclusion We have

  2. Procedural Portfolio Planning in Plastic Surgery, Part 2: Collaboration Between Surgeons and Hospital Administrators to Develop a Funds Flow Model for Procedures Performed at an Academic Medical Center.

    Science.gov (United States)

    Hultman, Charles Scott

    2016-06-01

    Although plastic surgeons make important contributions to the clinical, educational, and research missions of academic medical centers (AMCs), determining the financial value of a plastic surgery service can be difficult, due to complex cost accounting systems. We analyzed the financial impact of plastic surgery on an AMC, by examining the contribution margins and operating income of surgical procedures. We collaborated with hospital administrators to implement 3 types of strategic changes: (1) growth of areas with high contribution margin, (2) curtailment of high-risk procedures with negative contribution margin, (3) improved efficiency of mission-critical services with high resource consumption. Outcome measures included: facility charges, hospital collections, contribution margin, operating margin, and operating room times. We also studied the top 50 Current Procedural Terminology codes (total case number × charge/case), ranking procedures for profitability, as determined by operating margin. During the 2-year study period, we had no turnover in faculty; did not pursue any formal marketing; did not change our surgical fees, billing system, or payer mix; and maintained our commitment to indigent care. After rebalancing our case mix, through procedural portfolio planning, average hospital operating income/procedure increased from $-79 to $+816. Volume and diversity of cases increased, with no change in payer mix. Although charges/case decreased, both contribution margin and operating margin increased, due to improved throughput and decreased operating room times. The 5 most profitable procedures for the hospital were hernia repair, mandibular osteotomy, hand skin graft, free fibula flap, and head and neck flap, whereas the 5 least profitable were latissimus breast reconstruction, craniosynostosis repair, free-flap breast reconstruction, trunk skin graft, and cutaneous free flap. Total operating income for the hospital, from plastic surgery procedures, increased

  3. Development of a simple extraction procedure for chlorpyrifos determination in food samples by immunoassay.

    Science.gov (United States)

    Gabaldón, J A; Maquieira, A; Puchades, R

    2007-02-28

    The suitability of immunoassay methodology for rapid and accurate determination of chlorpyrifos in vegetables was tested. The optimised ELISA detection limit was 0.32ng/ml, with a working range from 0.69 to 6.21ng/ml and an immunoassay test-mid point (IC(50)) of 2.08ng/ml. A rapid sample preparation procedure considering different parameters such as the amount of sample, volume of extractant, extraction time and dilution factor was optimised. The developed direct extraction (DE) and multiresidue (ME) standard procedures were performed in different fortified fresh and processed vegetable samples (tomato, bonnet pepper, bean, pea, asparagus, broccoli, watermelon, melon, lettuce, cucumber, celery and red pepper). Recoveries were in all cases in the whole range 85.2-108.9% for both DE and ME extracts. Also, the comparison of the results obtained by both immunochemical and chromatographic methods for spiked fruits and vegetables were good with a correlation coefficient (r) of 0.97.

  4. Development of a draft of human factors safety review procedures for the Korean next generation reactor

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jung Woon; Moon, B. S.; Park, J. C.; Lee, Y. H.; Oh, I. S.; Lee, H. C. [Korea Atomic Energy Research Institute, Taejeon (Korea)

    2000-02-01

    In this study, a draft of human factors engineering (HFE) safety review procedures (SRP) was developed for the safety review of KNGR based on HFE Safety and Regulatory Requirements and Guidelines (SRRG). This draft includes acceptance criteria, review procedure, and evaluation findings for the areas of review including HFE Program Management, Human Factors Analyses, Human Factors Design, and HFE Verification and Validation, based on Section 15.1 'Human Factors Engineering Design Process' and 15.2 'Control Room Human Factors Engineering' of KNGR Specific Safety Requirements and Chapter 15 'Human Factors Engineering' of KNGR Safety Regulatory Guides. For the effective review, human factors concerns or issues related to advanced HSI design that have been reported so far should be extensively examined. In this study, a total of 384 human factors issues related to the advanced HSI design were collected through our review of a total of 145 documents. A summary of each issue was described and the issues were identified by specific features of HSI design. These results were implemented into a database system. 8 refs., 2 figs. (Author)

  5. Development of low-cost welding procedures for thick sections of HY-150 steel

    Science.gov (United States)

    Schmidt, P. M.; Snow, R. S.

    1972-01-01

    Low cost welding procedures were developed for welding 6-inch thick HY-150 steel to be used in the manufacture of large diameter motor case Y rings and nozzle attachment flanges. An extensive investigation was made of the mechanical and metallurgical properties and fracture toughness of HY-150 base plate and welds made with manual shielded metal arc process and semi-automatic gas metal arc process in the flat position. Transverse tensiles, all-weld metal tensiles, Charpy V-notch specimens and edge notched bend specimens were tested in the course of the program. In addition metallographic studies and hardness tests were performed on the weld, weld HAZ and base metal. The results of the work performed indicate that both the shielded metal arc and gas metal arc processes are capable of producing consistently sound welds as determined by radiographic and ultrasonic inspection. In addition, the weld metal, deposited by each process was found to exhibit a good combination of strength and toughness such that the selection of a rolled and welded procedure for fabricating rocket motor case components would appear to be technically feasible.

  6. Development of a draft of human factors safety review procedures for the Korean Next Generation Reactor

    International Nuclear Information System (INIS)

    Lee, Jung Woon; Moon, B. S.; Park, J. C.; Lee, Y. H.; Oh, I. S.; Lee, H. C.

    2000-02-01

    In this study, a draft of Human Factors Engineering (HFE) Safety Review Procedures (SRP) was developed for the safety review of KNGR based on HFE Safety and Regulatory Requirements and Guidelines (SRRG). This draft includes acceptance criteria, review procedure, and evaluation findings for the areas of review including HFE program management, human factors analyses, human factors design, and HFE verification and validation, based on section 15.1 'human factors engineering design process' and 15.2 'control room human factors engineering' of KNGR specific safety requirements and chapter 15 'human factors engineering' of KNGR safety regulatory guides. For the effective review, human factors concerns or issues related to advanced HSI design that have been reported so far should be extensively examined. In this study, a total of 384 human factors issues related to the advanced HSI design were collected through our review of a total of 145 documents. A summary of each issue was described and the issues were identified by specific features of HSI design. These results were implemented into a database system

  7. Development of Wall-Thinning Evaluation Procedure for Nuclear Power Plant Piping—Part 1: Quantification of Thickness Measurement Deviation

    Directory of Open Access Journals (Sweden)

    Hun Yun

    2016-06-01

    Full Text Available Pipe wall thinning by flow-accelerated corrosion and various types of erosion is a significant and costly damage phenomenon in secondary piping systems of nuclear power plants (NPPs. Most NPPs have management programs to ensure pipe integrity due to wall thinning that includes periodic measurements for pipe wall thicknesses using nondestructive evaluation techniques. Numerous measurements using ultrasonic tests (UTs; one of the nondestructive evaluation technologies have been performed during scheduled outages in NPPs. Using the thickness measurement data, wall thinning rates of each component are determined conservatively according to several evaluation methods developed by the United States Electric Power Research Institute. However, little is known about the conservativeness or reliability of the evaluation methods because of a lack of understanding of the measurement error. In this study, quantitative models for UT thickness measurement deviations of nuclear pipes and fittings were developed as the first step for establishing an optimized thinning evaluation procedure considering measurement error. In order to understand the characteristics of UT thickness measurement errors of nuclear pipes and fittings, round robin test results, which were obtained by previous researchers under laboratory conditions, were analyzed. Then, based on a large dataset of actual plant data from four NPPs, a quantitative model for UT thickness measurement deviation is proposed for plant conditions.

  8. Usability Testing for Developing Effective Interactive Multimedia Software: Concepts, Dimensions, and Procedures

    Directory of Open Access Journals (Sweden)

    Sung Heum Lee

    1999-04-01

    Full Text Available Usability testing is a dynamic process that can be used throughout the process of developing interactive multimedia software. The purpose of usability testing is to find problems and make recommendations to improve the utility of a product during its design and development. For developing effective interactive multimedia software, dimensions of usability testing were classified into the general categories of: learnability; performance effectiveness; flexibility; error tolerance and system integrity; and user satisfaction. In the process of usability testing, evaluation experts consider the nature of users and tasks, tradeoffs supported by the iterative design paradigm, and real world constraints to effectively evaluate and improve interactive multimedia software. Different methods address different purposes and involve a combination of user and usability testing, however, usability practitioners follow the seven general procedures of usability testing for effective multimedia development. As the knowledge about usability testing grows, evaluation experts will be able to choose more effective and efficient methods and techniques that are appropriate to their goals.

  9. Development of a rapid lateral flow immunoassay test for detection of exosomes previously enriched from cell culture medium and body fluids.

    Science.gov (United States)

    Oliveira-Rodríguez, Myriam; López-Cobo, Sheila; Reyburn, Hugh T; Costa-García, Agustín; López-Martín, Soraya; Yáñez-Mó, María; Cernuda-Morollón, Eva; Paschen, Annette; Valés-Gómez, Mar; Blanco-López, Maria Carmen

    2016-01-01

    Exosomes are cell-secreted nanovesicles (40-200 nm) that represent a rich source of novel biomarkers in the diagnosis and prognosis of certain diseases. Despite the increasingly recognized relevance of these vesicles as biomarkers, their detection has been limited due in part to current technical challenges in the rapid isolation and analysis of exosomes. The complexity of the development of analytical platforms relies on the heterogeneous composition of the exosome membrane. One of the most attractive tests is the inmunochromatographic strips, which allow rapid detection by unskilled operators. We have successfully developed a novel lateral flow immunoassay (LFIA) for the detection of exosomes based on the use of tetraspanins as targets. We have applied this platform for the detection of exosomes purified from different sources: cell culture supernatants, human plasma and urine. As proof of concept, we explored the analytical potential of this LFIA platform to accurately quantify exosomes purified from a human metastatic melanoma cell line. The one-step assay can be completed in 15 min, with a limit of detection of 8.54×10(5) exosomes/µL when a blend of anti-CD9 and anti-CD81 were selected as capture antibodies and anti-CD63 labelled with gold nanoparticles as detection antibody. Based on our results, this platform could be well suited to be used as a rapid exosome quantification tool, with promising diagnostic applications, bearing in mind that the detection of exosomes from different sources may require adaptation of the analytical settings to their specific composition.

  10. Development of a rapid lateral flow immunoassay test for detection of exosomes previously enriched from cell culture medium and body fluids

    Directory of Open Access Journals (Sweden)

    Myriam Oliveira-Rodríguez

    2016-08-01

    Full Text Available Exosomes are cell-secreted nanovesicles (40–200 nm that represent a rich source of novel biomarkers in the diagnosis and prognosis of certain diseases. Despite the increasingly recognized relevance of these vesicles as biomarkers, their detection has been limited due in part to current technical challenges in the rapid isolation and analysis of exosomes. The complexity of the development of analytical platforms relies on the heterogeneous composition of the exosome membrane. One of the most attractive tests is the inmunochromatographic strips, which allow rapid detection by unskilled operators. We have successfully developed a novel lateral flow immunoassay (LFIA for the detection of exosomes based on the use of tetraspanins as targets. We have applied this platform for the detection of exosomes purified from different sources: cell culture supernatants, human plasma and urine. As proof of concept, we explored the analytical potential of this LFIA platform to accurately quantify exosomes purified from a human metastatic melanoma cell line. The one-step assay can be completed in 15 min, with a limit of detection of 8.54×105 exosomes/µL when a blend of anti-CD9 and anti-CD81 were selected as capture antibodies and anti-CD63 labelled with gold nanoparticles as detection antibody. Based on our results, this platform could be well suited to be used as a rapid exosome quantification tool, with promising diagnostic applications, bearing in mind that the detection of exosomes from different sources may require adaptation of the analytical settings to their specific composition.

  11. Diagnosis and Dosimetry of Exposure to Sulfur Mustard: Development of Standard Operating Procedures; Further Exploratory Research on Protein Adducts

    National Research Council Canada - National Science Library

    Benschop, H

    1999-01-01

    .... Both procedures could be substantially shortened, while their sensitivities were improved. Furthermore, exploratory research is performed aiming at the development of a fieldable immunochemical assay for sulfur mustard adducts with proteins, i.e...

  12. Development and Analysis of Psychomotor Skills Metrics for Procedural Skills Decay.

    Science.gov (United States)

    Parthiban, Chembian; Ray, Rebecca; Rutherford, Drew; Zinn, Mike; Pugh, Carla

    2016-01-01

    In this paper we develop and analyze the metrics associated with a force production task involving a stationary target with the help of advanced VR and Force Dimension Omega 6 haptic device. We study the effects of force magnitude and direction on the various metrics namely path length, movement smoothness, velocity and acceleration patterns, reaction time and overall error in achieving the target. Data was collected from 47 participants who were residents. Results show a positive correlation between the maximum force applied and the deflection error, velocity while reducing the path length and increasing smoothness with a force of higher magnitude showing the stabilizing characteristics of higher magnitude forces. This approach paves a way to assess and model procedural skills decay.

  13. Development of procedures for the measurement of residual stress by neutron diffraction

    CERN Document Server

    Webster, G A

    2002-01-01

    Neutron diffraction is a non-destructive method for determining residual stresses in crystalline materials. It is a relatively new technique and no standard is currently available for making these measurements. This paper gives the background to research that has been carried out to develop a standard. It outlines the main findings and indicates the precautions that are required to achieve accurate positioning and alignment of specimens (and components) in a neutron beam and the analysis required to obtain reliable results. It also shows that special attention is needed in dealing with near-surface measurements because of surface aberration. It is demonstrated that, provided the recommended procedures are followed, a positional tolerance of +-0.1 mm can be achieved with an accuracy in strain of propor to 10 sup - sup 4 , to give a resolution in residual stress of propor to 7 to 20 MPa in most materials of practical interest. (orig.)

  14. Framing student dialogue and argumentation: Content knowledge development and procedural knowing in SSI inquiry group work

    Directory of Open Access Journals (Sweden)

    Anne Kristine Byhring

    2014-10-01

    Full Text Available In this article, we discuss the negotiation of the situated common ground in classroom conversations. Decision making on socioscientific issues (SSI includes norms of diverse funds of knowledge and interests. Arguments and justification may include warrants that cannot necessarily be weighed on the same scale. We discuss Roberts’ Visions 1 and 2 of scientific literacy as framing the common ground of classroom discussions. Two teacher–student dialogue sequences with 11th grade students from the Norwegian research project ElevForsk exemplify the negotiation of the situated common ground and the students’ deliberations. Our analysis examines what goes on in the thematic content, as well as at the interpersonal level of language use. Further, we suggest that different framings may complement each other and provide a space for the students’ emerging scientific conceptual development as well as for deliberation as a form of emerging procedural knowing.

  15. Developing standard performance testing procedures for material control and accounting components at a site

    International Nuclear Information System (INIS)

    Scherer, Carolynn P.; Bushlya, Anatoly V.; Efimenko, Vladimir F.; Ilyanstev, Anatoly; Regoushevsky, Victor I.

    2010-01-01

    The condition of a nuclear material control and accountability system (MC and A) and its individual components, as with any system combining technical elements and documentation, may be characterized through an aggregate of values for the various parameters that determine the system's ability to perform. The MC and A system's status may be functioning effectively, marginally or not functioning based on a summary of the values of the individual parameters. This work included a review of the following subsystems, MC and A and Detecting Material Losses, and their respective elements for the material control and accountability system: (a) Elements of the MC and A Subsystem - Information subsystem (Accountancy/Inventory), Measurement subsystem, Nuclear Material Access subsystem, including tamper-indicating device (TID) program, and Automated Information-gathering subsystem; (b) Elements for Detecting Nuclear Material Loses Subsystem - Inventory Differences, Shipper/receiver Differences, Confirmatory Measurements and differences with accounting data, and TID or Seal Violations. In order to detect the absence or loss of nuclear material there must be appropriate interactions among the elements and their respective subsystems from the list above. Additionally this work includes a review of regulatory requirements for the MC and A system component characteristics and criteria that support the evaluation of the performance of the listed components. The listed components had performance testing algorithms and procedures developed that took into consideration the regulatory criteria. The developed MC and A performance-testing procedures were the basis for a Guide for MC and A Performance Testing at the material balance areas (MBAs) of State Scientific Center of the Russian Federation - Institute for Physics and Power Engineering (SSC RF-IPPE).

  16. Understanding Nanoemulsion Formation and Developing a Procedure for Porous Material Growth using Assembled Nanoemulsions

    Science.gov (United States)

    Yeranossian, Vahagn Frounzig

    Nanoemulsions as an emerging technology have found many applications in consumer products, drug delivery, and even particle formation. However, knowledge gaps exist in how some of these emulsions are formed, specifically what pathways are traversed to reach the final state. Moreover, how these pathways affect the final properties of the nanoemulsions would affect the applications that these droplets possess. Some nanoemulsions possess unique properties, including the assembly of droplets. While the assembly of droplets is being studied in the Helgeson lab, work must be done to understand how the assembly itself could be used to control the growth of porous materials, such a hydrogels. Thus, this thesis aims to address two factors of nanoemulsions: the formation of water-in-oil nanoemulsions and the use of assemblying droplets in oil-in-water nanoemulsions to form macroporous hydrogels. To elucidate the formation mechanism of water-in-oil nanoemulsions, a combination of dynamic light scattering and small angle neutron scattering were used to study the intermediate and final states of the nanoemulsion during its formation. These nanoemulsions were prepared by slowly adding water to an oil and surfactant mixture and were diluted to effectively measure using scattering techniques without multiple scattering events. To develop a procedure to use assembled nanoemulsions for the growth of porous materials, a combination of optical microscopy and diffusional studies were employed. Optical microscopy images taken at various stages of the procedure help elucidate how the pore sizes of the final porous material is related to the droplet-rich domains of the assembled nanoemulsion. Meanwhile, diffusional measurements help confirm the size and interconnectedness of the macropores. From the work done in the completion of my thesis, the formation mechanism of the water-in-oil nanoemulsion studied has been elucidated. The neutron scattering measurements show that during the

  17. Development of a candidate secondary reference procedure (immunoassay based measurement procedure of higher metrological order) for cardiac troponin I: I. Antibody characterization and preliminary validation.

    Science.gov (United States)

    Noble, James E; Bunk, David M; Christenson, Robert H; Cole, Kenneth D; He, Hua-Jun; Katrukha, Alexei G; Panteghini, Mauro; Porter, Robert A; Schimmel, Heinz; Tate, Jillian R; Wang, Lili

    2010-11-01

    In this study, the first steps in the development of a secondary reference measurement procedure (RMP) 'higher metrological order measurement procedure' to support the cardiac troponin I (cTnI) standardization initiative is described. The RMP should be used to assign values to serum-based secondary reference materials (RMs) without analytical artifacts causing bias. A multiplexed bead-based assay and sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) were used to identify the optimum monoclonal antibody pair (clones 560 and 19C7) for the RMP. Using these antibodies, an ELISA-based procedure was developed to accurately measure the main cTnI forms present in blood. The proposed RMP appears to show no bias when tested on samples containing various troponin complexes, phosphorylated and dephosphorylated forms, and heparin. The candidate assay displayed suitable linearity and sensitivity (limit of detection, 0.052 μg/L) for the measurement of the proposed cTnI secondary RMs. Preliminary comparison data on patient samples with a commercial cTnI assay are also provided to support the suitability of RMP for value assignment to RMs. Full validation and final assessment of the RMP will be performed through transferability and inter-comparison studies.

  18. Strategic environmental assessment and national development plans in Turkey: Towards legal framework and operational procedure

    International Nuclear Information System (INIS)

    Say, Nuriye Peker; Yuecel, Muzaffer

    2006-01-01

    National development plans were started to be prepared in Turkey in 1963. These plans are mandatory for public investments and guiding principles for private investments. They have a quality which guides and sets objectives for other plans in the country. Therefore, they can be evaluated as the main reason of successes and failures of sectoral investments or the problems that they cause directly or indirectly. Turkey is undergoing rapid industrialization, urbanization and population growth, thus environmental problems are on the increase. Although Environmental Impact Assessment (EIA) has been applied to individual investments in Turkey since 1993, natural environment has continued to be affected because of human activities. Today, parallel to the developments in the world, it has been discussed that it is necessary to strengthen project-level Environmental Assessment (EA) and to practice Strategic Environmental Assessment (SEA). The interest in SEA, that is, EA at the level of proposed policies, plans and programs has grown significantly since 2000 in the country. Discussions and preparations have started about regulation which provides the legal and institutional framework for SEA in The Ministry of Environment and Forestry. However, since the scientific approach into the subject is very new in Turkey, it will take time to answer the questions about how and in what fields to practice. This research project aims at analyzing the possible practice opportunities of SEA in Turkey and the practicability of SEA into the National Five-Year Development Plan (FYDP) which is assumed at the highest level of planning hierarchy in the country. The research is conducted on two sections. In the first section, procedural approaches to SEA on national development plans are investigated and a framework for these approaches is adapted at the institutional level. In the second section, SEA form for energy sector in the development plans is developed. In this article, the findings

  19. Qualitative research within trials: developing a standard operating procedure for a clinical trials unit

    Science.gov (United States)

    2013-01-01

    Background Qualitative research methods are increasingly used within clinical trials to address broader research questions than can be addressed by quantitative methods alone. These methods enable health professionals, service users, and other stakeholders to contribute their views and experiences to evaluation of healthcare treatments, interventions, or policies, and influence the design of trials. Qualitative data often contribute information that is better able to reform policy or influence design. Methods Health services researchers, including trialists, clinicians, and qualitative researchers, worked collaboratively to develop a comprehensive portfolio of standard operating procedures (SOPs) for the West Wales Organisation for Rigorous Trials in Health (WWORTH), a clinical trials unit (CTU) at Swansea University, which has recently achieved registration with the UK Clinical Research Collaboration (UKCRC). Although the UKCRC requires a total of 25 SOPs from registered CTUs, WWORTH chose to add an additional qualitative-methods SOP (QM-SOP). Results The qualitative methods SOP (QM-SOP) defines good practice in designing and implementing qualitative components of trials, while allowing flexibility of approach and method. Its basic principles are that: qualitative researchers should be contributors from the start of trials with qualitative potential; the qualitative component should have clear aims; and the main study publication should report on the qualitative component. Conclusions We recommend that CTUs consider developing a QM-SOP to enhance the conduct of quantitative trials by adding qualitative data and analysis. We judge that this improves the value of quantitative trials, and contributes to the future development of multi-method trials. PMID:23433341

  20. Qualitative research within trials: developing a standard operating procedure for a clinical trials unit.

    Science.gov (United States)

    Rapport, Frances; Storey, Mel; Porter, Alison; Snooks, Helen; Jones, Kerina; Peconi, Julie; Sánchez, Antonio; Siebert, Stefan; Thorne, Kym; Clement, Clare; Russell, Ian

    2013-02-21

    Qualitative research methods are increasingly used within clinical trials to address broader research questions than can be addressed by quantitative methods alone. These methods enable health professionals, service users, and other stakeholders to contribute their views and experiences to evaluation of healthcare treatments, interventions, or policies, and influence the design of trials. Qualitative data often contribute information that is better able to reform policy or influence design. Health services researchers, including trialists, clinicians, and qualitative researchers, worked collaboratively to develop a comprehensive portfolio of standard operating procedures (SOPs) for the West Wales Organisation for Rigorous Trials in Health (WWORTH), a clinical trials unit (CTU) at Swansea University, which has recently achieved registration with the UK Clinical Research Collaboration (UKCRC). Although the UKCRC requires a total of 25 SOPs from registered CTUs, WWORTH chose to add an additional qualitative-methods SOP (QM-SOP). The qualitative methods SOP (QM-SOP) defines good practice in designing and implementing qualitative components of trials, while allowing flexibility of approach and method. Its basic principles are that: qualitative researchers should be contributors from the start of trials with qualitative potential; the qualitative component should have clear aims; and the main study publication should report on the qualitative component. We recommend that CTUs consider developing a QM-SOP to enhance the conduct of quantitative trials by adding qualitative data and analysis. We judge that this improves the value of quantitative trials, and contributes to the future development of multi-method trials.

  1. Development of experimental method for self-wastage behavior in sodium-water reaction. Development of test rig (SWAT-2R) and study for experimental procedure

    International Nuclear Information System (INIS)

    Abe, Yuta; Shimoyama, Kazuhito; Kurihara, Akikazu

    2014-07-01

    In case of water leak from a penetrated crack on a tube of steam generator in the sodium cooled fast reactor (SFR), self-wastage, that increases the size of leak, may take place by corrosion related to chemical reaction between sodium and water. If the self-wastage continues in a certain period of time, the intact tube bundle may be damaged as a result of enlarged leak. For the safety evaluation of the accident, JAEA has been developing the analytical method of self-wastage using the multi-dimensional sodium-water reaction code. Experiments conducted so far used mainly crack-type test pieces. However, reproducibility was limited and it was difficult to evaluate individual effects of the phenomena in detail. This report describes the development of new experimental rig (SWAT-2R). SWAT-2R enables to examine corrosion effecting factors that were ambiguous in the previous studies. The report includes description of development of micro-leak test piece, examination of experimental procedure. The results will provide fundamental data for validation of the self-wastage analytical method. (author)

  2. Developing an automated database for monitoring ultrasound- and computed tomography-guided procedure complications and diagnostic yield.

    Science.gov (United States)

    Itri, Jason N; Jones, Lisa P; Kim, Woojin; Boonn, William W; Kolansky, Ana S; Hilton, Susan; Zafar, Hanna M

    2014-04-01

    Monitoring complications and diagnostic yield for image-guided procedures is an important component of maintaining high quality patient care promoted by professional societies in radiology and accreditation organizations such as the American College of Radiology (ACR) and Joint Commission. These outcome metrics can be used as part of a comprehensive quality assurance/quality improvement program to reduce variation in clinical practice, provide opportunities to engage in practice quality improvement, and contribute to developing national benchmarks and standards. The purpose of this article is to describe the development and successful implementation of an automated web-based software application to monitor procedural outcomes for US- and CT-guided procedures in an academic radiology department. The open source tools PHP: Hypertext Preprocessor (PHP) and MySQL were used to extract relevant procedural information from the Radiology Information System (RIS), auto-populate the procedure log database, and develop a user interface that generates real-time reports of complication rates and diagnostic yield by site and by operator. Utilizing structured radiology report templates resulted in significantly improved accuracy of information auto-populated from radiology reports, as well as greater compliance with manual data entry. An automated web-based procedure log database is an effective tool to reliably track complication rates and diagnostic yield for US- and CT-guided procedures performed in a radiology department.

  3. Developing and Institutionalising Supply Chain Management Procedures: A Case Study of the Eastern Cape Dept of Roads and Public Works

    Directory of Open Access Journals (Sweden)

    Vukile Dlova

    2014-03-01

    Full Text Available This article presents findings from a case study research in the Eastern Cape Department of Roads and Public Works. It systematically investigates why public institutions fail to implement their Supply Change Management (SCM policies and procedures. The article provides a clear context for the researchand explains why policies and procedures are vital for organisations. It also illustrateshow policies and procedures are a meansto effective supply chain systems and describes the research method, population and sample. Findings based on the set outcriteria for good institutionalisation of policies and procedures showed that although SCM policies and procedures areprovided to employees and they were aware of the existence of theseinstruments, there was very little participation of employees in the development and review of these policies.  Based on the findings of the research, a key recommendation is that practitioners, are involved in the day to day implementation of the SCM process in public institutions, should also be involved in the development processes of SCM policies and procedures. The research also argues that for public institutions to be effective and efficient, clear departmental guidelines should be simple and straight forward language should be used so as to avoid different interpretations by implementers. These two critical points will contribute to the effective and efficient development and institutionalization of SCM policies and procedures in government institutions.

  4. The Eukaryotic Microbiome: Origins and Implications for Fetal and Neonatal life note bene: previous titles: The Microbiome in the Development of Terrestrial Life,and,The Origins and Development of the Neonatal Microbiome

    Directory of Open Access Journals (Sweden)

    William B. Miller

    2016-09-01

    Full Text Available All eukaryotic organisms are holobionts representing complex collaborations between the entire microbiome of each eukaryote and its innate cells. These linked constituencies form complex localized and interlocking ecologies in which the specific microbial constituents and their relative abundance differ substantially according to age and environmental exposures. Rapid advances in microbiology and genetic research techniques have uncovered a significant previous underestimate of the extent of that microbial contribution and its metabolic and developmental impact on holobionts. Therefore, a re-calibration of the neonatal period is suggested as a transitional phase in development that includes the acquisition of consequential collaborative microbial life from extensive environmental influences. These co-dependent, symbiotic relationships formed in the fetal and neonatal stages extend into adulthood and even across generations.

  5. Development of a standard test procedure for devices on thermal weed control

    Directory of Open Access Journals (Sweden)

    Verschwele, Arnd

    2016-02-01

    Full Text Available In contrast to the standard evaluation of the efficacy of pesticides and the testing of spraying equipment there are no comparable testing procedure for equipment of thermal weed control. It is the aim of the investigations described here to develop a standard procedure for assessing temperature distribution and biological efficacy. This will be the basis for quality testing which can be directly used by practical users. Also it can help engineers to improve devices if constructive gaps will be identified by these tests. The results from testing a flaming device (Green-Flame 850 E demonstrated such a potential for technical improvement: The temperature decreased from 159 °C to 89 °C by increasing driving speed from 0.35 m/s to 0.81 m/s. The variation of the temperature related to the working width was extremely high: The range was 60 °C at highest speed and 79 °C at lowest speed, respectively. The biological efficacy against the test plant species Sinapis arvensis was also affected by the driving speed and the corresponding temperature. A driving speed not higher than 0.53 m/s resulted in efficacy rates of almost 95%. However, the efficacy was only 66% at the highest tested speed of 0.81 m/s. Thus, the needed effective temperature is between 89 °C und 106 °C. In contrast, Lolium perenne was controlled by only 72% under the tested conditions. Here a dose-response relationship was not observed. The variation of the temperature, as well as the biological efficacy, was extremely heterogeneous and not satisfying in terms of an economic and safe use. Similar results were found for other devices on thermal weed control.

  6. Crush performance of redwood for developing design procedures for impact limiters

    International Nuclear Information System (INIS)

    Cramer, S.M.; Hermanson, J.C.; McMurtry, W.M.

    1995-01-01

    Containers for the transportation of hazardous and radioactive materials incorporate redwood in impact limiters. Redwood is an excellent energy absorber, but only the most simplistic information exists on its crush properties. Tbe stress-strain interrelationship for any wood species subject to three-dimensional stresses is largely unknown for any all stress condition and wood behavior at both high strains and high strain-rates is known only in general terms. Both stress-strain and crush failure theories have been developed based only on uniaxial load tests. The anisotropy of wood adds an additional complexity to measuring wood response and developing suitable theories to describe it. A long history of wood utilization in the building industry has led to design procedures and property information related to simple uniaxial loadings that do not inflict damage to the wood. This lack of knowledge may be surprising for a material that has a long history of engineered use, but the result is difficulty in utilizing wood in more sophisticated designs such as impact limiters. This study provides a step toward filling the information gap on wood material response for high performance applications such as impact limiters

  7. Procedure Developed for Ballistic Impact Testing of Composite Fan Containment Concepts

    Science.gov (United States)

    Pereira, J. Michael; Melis, Matthew E.

    1998-01-01

    The fan-containment system in a jet engine is designed to prevent a fan blade from penetrating the engine case in the event that the blade or a portion of the blade separates from the rotor during operation. Usually, these systems consist of a thick metal case that is strong enough to survive such an impact. Other systems consist of a dry aramid fabric wrapped around a relatively thin metal case. In large turbofan engines, metal-containment systems can weigh well over 300 kg, and there is a strong impetus to reduce their weight. As a result, the NASA Lewis Research Center is involved in an effort to develop polymer matrix composite (PMC) fan-containment systems to reduce the weight and cost while maintaining the high levels of safety associated with current systems. Under a Space Act Agreement with AlliedSignal Aircraft Engines, a new ballistic impact test procedure has been developed to quantitatively evaluate the performance of polymer matrix composite systems.

  8. Development of seismic safety reevaluation procedure considering the ageing of NPP facilities

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Myoung Kue [Jeonju Univ., Cheonju (Korea, Republic of); Kim, J. M. [Cheonnam National Univ., Gwangju (Korea, Republic of); Kim, Y. S.; Cheong, S. H.; Kim, I. S.; Lee, M. G.; Kim, D. O. [Andong National Univ., Andong (Korea, Republic of); Lee, G. H. [Mokpo National Maritime Univ., Mokpo (Korea, Republic of)

    2003-03-15

    There are three of Nuclear Power Plants subject to the USI A-46 in Korea, including Kori No 1 and No 2 and Wolsung No 1. For the sake of resolution of the issue the possibility of adopting the GIP developed by the SQUG in USA is very high. In relation to the issue, this study addresses some technical improvements of the GIP including sloshing analysis based on multiple modes, seismic retrofit of cabinet for reduction of ICRS and modification of IRS depending on damping ratio. Dominant degradation factor and its affects NPP concrete elements are reviewed : chloride induced corrosion, carbonation of concrete elements, freezing and thawing of concrete elements, chemical and biological process, crack affect on concrete degradation. Various technical reports and papers about age-related degradation are reviewed for identification of degradation properties of NPP structures and components and degradation trend in NPP structures and components. This report summarizes numerical model for concrete degradation and development procedure of numerical models for concrete degradation. This report proposes the research necessity for performance evaluation of degraded concrete structure and selection of element for further study.

  9. Mathematical études: embedding opportunities for developing procedural fluency within rich mathematical contexts

    Science.gov (United States)

    Foster, Colin

    2013-07-01

    In a high-stakes assessment culture, it is clearly important that learners of mathematics develop the necessary fluency and confidence to perform well on the specific, narrowly defined techniques that will be tested. However, an overemphasis on the training of piecemeal mathematical skills at the expense of more independent engagement with richer, multifaceted tasks risks devaluing the subject and failing to give learners an authentic and enjoyable experience of being a mathematician. Thus, there is a pressing need for mathematical tasks which embed the practice of essential techniques within a richer, exploratory and investigative context. Such tasks can be justified to school management or to more traditional mathematics teachers as vital practice of important skills; at the same time, they give scope to progressive teachers who wish to work in more exploratory ways. This paper draws on the notion of a musical étude to develop a powerful and versatile approach in which these apparently contradictory aspects of teaching mathematics can be harmoniously combined. I illustrate the tactic in three central areas of the high-school mathematics curriculum: plotting Cartesian coordinates, solving linear equations and performing enlargements. In each case, extensive practice of important procedures takes place alongside more thoughtful and mathematically creative activity.

  10. Quantitative evaluation of geodiversity: development of methodological procedures with application to territorial management

    Science.gov (United States)

    Forte, J.; Brilha, J.; Pereira, D.; Nolasco, M.

    2012-04-01

    Although geodiversity is considered the setting for biodiversity, there is still a huge gap in the social recognition of these two concepts. The concept of geodiversity, less developed, is now making its own way as a robust and fundamental idea concerning the abiotic component of nature. From a conservationist point of view, the lack of a broader knowledge concerning the type and spatial variation of geodiversity, as well as its relationship with biodiversity, makes the protection and management of natural or semi-natural areas incomplete. There is a growing need to understand the patterns of geodiversity in different landscapes and to translate this knowledge for territorial management in a practical and effective point of view. This kind of management can also represent an important tool for the development of sustainable tourism, particularly geotourism, which can bring benefits not only for the environment, but also for social and economic purposes. The quantification of geodiversity is an important step in all this process but still few researchers are investing in the development of a proper methodology. The assessment methodologies that were published so far are mainly focused on the evaluation of geomorphological elements, sometimes complemented with information about lithology, soils, hidrology, morphometric variables, climatic surfaces and geosites. This results in very dissimilar areas at very different spatial scales, showing the complexity of the task and the need of further research. This current work aims the development of an effective methodology for the assessment of the maximum elements of geodiversity possible (rocks, minerals, fossils, landforms, soils), based on GIS routines. The main determinant factor for the quantitative assessment is scale, but other factors are also very important, such as the existence of suitable spatial data with sufficient degree of detail. It is expected to attain the proper procedures in order to assess geodiversity

  11. Development of utility generic functional requirements for electronic work packages and computer-based procedures

    Energy Technology Data Exchange (ETDEWEB)

    Oxstrand, Johanna [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2017-06-01

    The Nuclear Electronic Work Packages - Enterprise Requirements (NEWPER) initiative is a step toward a vision of implementing an eWP framework that includes many types of eWPs. This will enable immediate paper-related cost savings in work management and provide a path to future labor efficiency gains through enhanced integration and process improvement in support of the Nuclear Promise (Nuclear Energy Institute 2016). The NEWPER initiative was organized by the Nuclear Information Technology Strategic Leadership (NITSL) group, which is an organization that brings together leaders from the nuclear utility industry and regulatory agencies to address issues involved with information technology used in nuclear-power utilities. NITSL strives to maintain awareness of industry information technology-related initiatives and events and communicates those events to its membership. NITSL and LWRS Program researchers have been coordinating activities, including joint organization of NEWPER-related meetings and report development. The main goal of the NEWPER initiative was to develop a set of utility generic functional requirements for eWP systems. This set of requirements will support each utility in their process of identifying plant-specific functional and non-functional requirements. The NEWPER initiative has 140 members where the largest group of members consists of 19 commercial U.S. nuclear utilities and eleven of the most prominent vendors of eWP solutions. Through the NEWPER initiative two sets of functional requirements were developed; functional requirements for electronic work packages and functional requirements for computer-based procedures. This paper will describe the development process as well as a summary of the requirements.

  12. Support in the development of Regulatory Procedures for licensing Lepse Waste Management Operations

    International Nuclear Information System (INIS)

    2001-05-01

    This report describes a project intended to assist Gosatomnadzor of Russia develop a set of documents defining the regulatory requirements for information to be submitted to Gosatomnadzor in support of any application for a licence relating to the removal of spent nuclear fuel from the depot ship Lepse. The project resulted in the development of three regulatory documents covering the documentation required in support of a licence application, the requirements for quality assurance arrangements and the safety analysis report. The working method adopted involved staged development of draft material and review at workshops involving a wide variety of relevant Russian and western organizations. The input and output of the workshops was fully documented to provide an audit trail for the document development and the rationale for what has been included and what is excluded and why. The availability of the regulatory documents in English should significantly assist in the use of the documents by western partners in the actual industrial project. Important experience and information was exchanged among participants in the project. The developing understanding is an important element in providing confidence, from a western perspective, that appropriate regulatory supervision can be applied to industrial projects supported by organizations such as the European Commission and national agencies. The same working methods could be used in the next phase of Lepse regulatory support, i.e., support in development of the procedures for the regulatory review of licence applications, and, subsequently, support in the application of the regulatory inspection process to ensure licence conditions are being complied with. Similarly, these working methods could be used in providing regulatory support for nuclear and radiation safety related to other industrial projects involving radioactive waste management. The participants in this sub-project described in this report were Norwegian

  13. Development and validation of a screening procedure to identify speech-language delay in toddlers with cleft palate

    DEFF Research Database (Denmark)

    Jørgensen, Line Dahl; Willadsen, Elisabeth

    2017-01-01

    The purpose of this study was to develop and validate a clinically useful speech-language screening procedure for young children with cleft palate +/- cleft lip (CP) to identify those in need of speech-language intervention. Twenty-two children with CP were assigned to a +/- need for intervention...... SLPs, indicating that the screening procedure is a valid way of identifying children with CP who need early intervention. Keywords: Cleft palate, cleft palate speech, early intervention, speech-language screening...

  14. Civil Procedure.

    Science.gov (United States)

    Byer, Robert

    1997-01-01

    Briefly reviews the historical development of civil procedure (the rules that dictate how a civil case can proceed through the courts) and identifies some of its main components. Discusses procedures such as subject matter jurisdiction, personal jurisdiction, venue, discovery, motions practice, pleadings, pretrial conference, and trials. (MJP)

  15. Development of a standard operating procedure for mammography equipment used in calibration of ionized chambers

    International Nuclear Information System (INIS)

    Rodrigues, Yklys Santos; Potiens, Maria da Penha Albuquerque

    2011-01-01

    Mammography is one widely used technique in the detection of breast cancer. In order to optimize the results achieving better images with lower dose rates, a quality assurance programme must be applied to the equipment. Some control tests use ionization chambers to measure air kerma and other quantities. These tests can only be reliable if the ionization chambers used on them are correctly calibrated. In the present work, it was developed a standard operating procedure (SOP) for quality control tests in a commercial mammography equipment installed in the Calibration Laboratory (LCI) at IPEN - Brazilian Institute for energy and nuclear research). Seven tests were performed in the equipment: Tube voltage and exposition time accuracy and reproducibility, linearity and reproducibility of Air kerma and Half Value Layer (HVL). Then, it was made a measurement of the air kerma in the mammography equipment, using a reference ionization chamber with traceability to a primary laboratory in Germany (Physikalisch-Technische Bundesanstalt - PTB), that was later compared with the air kerma measured in an industrial irradiator. This industrial X-ray generator was recently used in the implementation of X-radiation Standards beams, mammography level, following the Standard IEC 61267. The HVL values varied from 0.36 (25kV) to 0.41 mmA1 (35kV), and the measured air kerma rates were between 9.78 and 17.97 mGy/min. (author)

  16. Development of a Portable Training Tool for Simulating Visceral Angiographic Procedures for Beginners

    International Nuclear Information System (INIS)

    Yamagami, Takuji; Osuga, Keigo; Yoshimatsu, Rika; Matsumoto, Tomohiro; Miura, Hiroshi; Terayama, Koshi; Anai, Hiroshi; Takahashi, Masahide; Hasebe, Terumitsu; Nishimura, Tsunehiko

    2009-01-01

    The purpose of this study was to evaluate the usefulness of a tool that we developed to simulate performance of visceral angiography to train beginners in the field of splanchnic angiography. Seven residents and two fellows who were rotating within the Division of Interventional Radiology at our institution between June and August 2008 participated in the evaluation of this tool. They had no experience in performing visceral angiography as an operator. Time for selection of arterial branches arising from the celiac axis on the model was measured before and after training. After such training, the participants performed actual visceral angiography as an operator with instructors beside them. Success of the trainees in selecting visceral arterial branches was evaluated in these real-life cases. In the first test using the model, seven of nine trainees (77.8%) succeeded in selecting all required arteries, while the remaining two failed to select all required arteries. After training using the model, all trainees succeeded in selecting all required arteries just before the actual angiographic study. In the actual angiography, the catheter was successfully inserted from the femoral artery and advanced to the superior mesenteric, celiac, splenic, common hepatic, gastroduodenal, and right and left hepatic arteries by all trainees with only two exceptions. In conclusion, this tool is helpful for training beginners in visceral angiographic procedures.

  17. The development of lavage procedures for the upper and lower respiratory tract of the cat

    International Nuclear Information System (INIS)

    McCarthy, Grainne; Quinn, P.J.

    1986-01-01

    New techniques for routine bronchopulmonary lavage (BPL) and nasal flushing in the anaesthetized cat which are safe, reproducible and simple to use have been developed. Five adult mixed-breed cats from a specific pathogen-free colony were selected, fasted overnight and weighed. The feeding tube was passed through the endotracheal tube and down the trachea until it became wedged in the bronchus. Nasal flushing was then immediately carried out after the BPL with the endotracheal tube in position. Radiological and fluoroscopic examinations were carried out to determine the position of the feeding tube in the lung. Lateral and dorsoventral views of the thorax of each cat were taken. These examinations identified the tube most frequently in the caudal lobe of the lung. The lavage techniques described provide a definite procedure for investigating the cellular and humoral mechanisms operating in the upper and lower respiratory tract of the cat. These methods can be used to sample directly the cellular and humoral constituents contributing to defence mechanisms in the feline respiratory tract and to monitor the local changes accompanying respiratory disease

  18. Manpower development for safe operation of nuclear power plant. China. Emergency operating procedures. Activity: 5.1.4-Task-11. Technical report

    International Nuclear Information System (INIS)

    Walsh, L.A.

    1994-01-01

    This report covers the period of engagement from July 11, 1994 through July 22, 1994. The events and topics of discussion are as follows: History of Emergency Operating Procedure EOP Development; Emergency Operating Procedures (Event Based, Critical Safe Function Status Trees and Functional Recovery Response Procedures); Transition from Emergency Operating Procedures to Severe Accident Management Guidelines

  19. The investigation of the effectiveness on the educational procedure development for physical therapist assistant in Quang Tri province of Vietnam.

    Science.gov (United States)

    Noh, JinWon; Kim, Min Hee; Yoo, Ki-Bong; Kim, Eun Joo

    2017-09-01

    [Purpose] The purpose of the present study was to investigate the effectiveness on the educational procedure development for physical therapist assistant in Quang Tri province of Vietnam. [Subjects and Methods] The subjects consisted of 10 lecturers for the education of physical therapist assistant in Quang Tri medical college. To compare with satisfaction and educational effectiveness according to the participation of educational procedure, the lecturers conducted the survey research. [Results] In the descriptive values of participant satisfaction in educational procedure, most of the scored were higher than 4. There was no significance in the difference between the satisfaction in educational procedure according to gender and degree. However, there was some significance in class according to major. To investigate the educational effectiveness, 5 domains about knowledge of physical therapist assistant included 4 questions each were evaluated the understanding level before and after the education. In all domains, the understanding level after education was notably higher than before. [Conclusion] The present study was to the satisfaction and effectiveness of the educational procedure for physical therapist assistant reflecting the regional specialty in this area. The development of educational procedure for physical therapist assistant helps to improve the situation where the medical specialists for rehabilitation are insufficient.

  20. Development of an optimized procedure bridging design and structural analysis codes for the automatized design of the SMART

    International Nuclear Information System (INIS)

    Kim, Tae Wan; Park, Keun Bae; Choi, Suhn; Kim, Kang Soo; Jeong, Kyeong Hoon; Lee, Gyu Mahn

    1998-09-01

    In this report, an optimized design and analysis procedure is established to apply to the SMART (System-integrated Modular Advanced ReacTor) development. The development of an optimized procedure is to minimize the time consumption and engineering effort by squeezing the design and feedback interactions. To achieve this goal, the data and information generated through the design development should be directly transferred to the analysis program with minimum operation. The verification of the design concept requires considerable effort since the communication between the design and analysis involves time consuming stage for the conversion of input information. In this report, an optimized procedure is established bridging the design and analysis stage utilizing the IDEAS, ABAQUS and ANSYS. (author). 3 refs., 2 tabs., 5 figs

  1. Development of an ICF-based eligibility procedure for education in Switzerland.

    Science.gov (United States)

    Hollenweger, Judith

    2011-05-31

    Starting in January 2011, Switzerland will implement a multidimensional, context-sensitive procedure to establish eligibility in education systems. This paper provides a brief overview of the different eligibility-related practices with a special focus on children with disabilities. The paper then outlines the philosophical and conceptual framework of the eligibility procedure based on the International Classification of Functioning, Disability and Health, and the UN Convention on the Rights of Persons with Disability. The different components and methodology applied to organise information in the process towards establishing eligibility are also presented. Finally, some observations are made regarding transparent and just applications of the eligibility procedure, and the implementation of this new eligibility procedure.

  2. Development of transmucosal patch loaded with anesthetic and analgesic for dental procedures and in vivo evaluation

    Directory of Open Access Journals (Sweden)

    Nidhi M

    2016-06-01

    Full Text Available Malviya Nidhi,1 M Nagaraju Patro,1 Somisetty Kusumvalli,2 Vemula Kusumdevi1 1Department of Pharmaceutics, Al-Ameen College of Pharmacy, 2Department of Endodontics and Conservative Dentistry, Sri Rajiv Gandhi College of Dental Sciences, Bengaluru, Karnataka, India Abstract: Most of the dental surgeries require preoperative anesthetic and postoperative analgesic for painless procedures. A multidrug transmucosal drug delivery system loaded with lignocaine (Lig base for immediate release and solid lipid nanoparticles (SLNs of diclofenac (Dic diethylamine for prolonged release was developed. SLNs were prepared by solvent emulsion–evaporation method with Precirol ATO 5 and Geleol as lipids and Pluronic F 68 as surfactant and optimized with Box–Behnken design for particle size and entrapment efficiency. SLNs were incorporated into the transmucosal patch (TP prepared with hydroxypropyl cellulose-LF (HPC-LF and with a backing layer of ethyl cellulose. Optimized SLNs and TP were characterized for Fourier transform infrared spectrophotometry, differential scanning calorimetry, scanning electron microscopy, X-ray diffraction, in vitro release, ex vivo permeation through porcine buccal mucosa, Caco-2 permeability, and residual solvent analysis by gas chromatography. The TP was also evaluated for swelling index, in vitro residence time, tensile strength, and mucoadhesive strength. Preclinical pharmacokinetic, pharmacodynamic, and histopathological studies by application of TP on the gingiva of New Zealand rabbits were carried out. Particle size and entrapment efficiency of the optimized SLN “S8” were determined as 98.23 nm and 84.36%, respectively. The gingival crevicular fluid and tissue concentrations were greater than plasma concentrations with increase in Cmax and area under the curve (AUC of Lig and Dic when compared to the control group. Pain perception by needle prick showed prolonged combined anesthetic and analgesic effect. The developed TP

  3. Preliminary development of flaw evaluation procedures for delayed hydride cracking initiation under hydride non-ratcheting conditions

    Energy Technology Data Exchange (ETDEWEB)

    Xu, S.; Cui, J.; Kawa, D.; Shek, G.K.; Scarth, D.A. [Kinectrics Inc., Toronto, Ontario (Canada)

    2006-07-01

    The flaw evaluation procedure for Delayed Hydride Cracking (DHC) initiation currently provided in the CSA Standard N285.8 was developed for hydride ratcheting conditions, in which flaw-tip hydrides do not completely dissolve at peak temperature. Test results have shown that hydrided regions formed under non-ratcheting conditions, in which flaw-tip hydrides completely dissolve at peak temperature, have significantly higher resistance to cracking than those formed under ratcheting conditions. This paper presents some preliminary work on the development of a procedure for the evaluation of DHC initiation for flaws under hydride non-ratcheting conditions. (author)

  4. Development of quality control procedures for mass produced and released Bactrocera Philippinensis (Diptera: Tephritidae) for sterile insect technique programs

    International Nuclear Information System (INIS)

    Resilva, S.; Obra, G.; Zamora, N.; Gaitan, E.

    2007-01-01

    Quality control procedures for Bactrocera philippinensis Drew and Hancock 1994 (Diptera: Tephritidae) used in sterile insect technique (SIT) programs were established in the mass rearing facility at the Philippine Nuclear Research Institute. Basic studies on pupal irradiation, holding/packaging systems, shipping procedures, longevity, sterility studies, and pupal eye color determination in relation to physiological development at different temperature regimes were investigated. These studies will provide baseline data for the development of quality control protocols for an expansion of B. philippinensis field programs with an SIT component in the future. (author) [es

  5. Measuring nursing advocacy in procedural pain care--development and validation of an instrument.

    Science.gov (United States)

    Vaartio, Heli; Leino-Kilpi, Helena; Suominen, Tarja; Puukka, Pauli

    2009-12-01

    Nursing advocacy has been defined in several ways, but its structure has not been operationalized. Therefore, different theoretical aspects of advocacy have not been able to be verified empirically. Our aim was to validate the content and structure of the concept of nursing advocacy within procedural pain care from the point of view of both patients and nurses. The concept of nursing advocacy was outlined first by integrative literature review and then delineated with data of semi-structured interviews among adult internal medicine and surgical patients and nurses (phases I-II). Then, the instrument was developed with facet-design approach, and the content and construct validity of it established in two subsamples within otolaryngeal surgical care (phases III-V). These descriptive and explorative studies were conducted from 2003 to 2007 in a total of 12 Finnish hospitals. The findings supported the validity of both the concept and the instrument. Pearson correlations and Cronbach alphas supported the conceptual dimensions of advocacy operationalized in this instrument. Internal consistency validity of the instrument scales were supported by subscale CVI, which ranged from 0.97 to 0.99, and item CVI, which ranged from 0.93 to 1.00. The instrument structure was strengthened with exploratory factor analysis, which explained 65% (sample of patients) or 57% (sample of nurses) of the variance in antecedents, 75% or 74% of the variance in activities, and 60% or 56% of the variance in the consequences of advocacy. This four-part 56-item (58-item for nurses) instrument promises to measure the dimensions of nursing advocacy. However, the instrument needs further validation in different settings.

  6. Development and Optimization of a Flocculation Procedure for Improved Solid-Liquid Separation of Digested Biomass

    Energy Technology Data Exchange (ETDEWEB)

    Patton, Caroline; Lischeske, James J.; Sievers, David A.

    2015-11-03

    One viable treatment method for conversion of lignocellulosic biomass to biofuels begins with saccharification (thermochemical pretreatment and enzymatic hydrolysis), followed by fermentation or catalytic upgrading to fuels such as ethanol, butanol, or other hydrocarbons. The post-hydrolysis slurry is typically 4-8 percent insoluble solids, predominantly consisting of lignin. Suspended solids are known to inhibit fermentation as well as poison catalysts and obstruct flow in catalyst beds. Thus a solid-liquid separation following enzymatic hydrolysis would be highly favorable for process economics, however the material is not easily separated by filtration or gravimetric methods. Use of a polyacrylamide flocculant to bind the suspended particles in a corn stover hydrolyzate slurry into larger flocs (1-2mm diameter) has been found to be extremely helpful in improving separation. Recent and ongoing research on novel pretreatment methods yields hydrolyzate material with diverse characteristics. Therefore, we need a thorough understanding of rapid and successful flocculation design in order to quickly achieve process design goals. In this study potential indicators of flocculation performance were investigated in order to develop a rapid analysis method for flocculation procedure in the context of a novel hydrolyzate material. Flocculation conditions were optimized on flocculant type and loading, pH, and mixing time. Filtration flux of the hydrolyzate slurry was improved 170-fold using a cationic polyacrylamide flocculant with a dosing of approximately 22 mg flocculant/g insoluble solids at an approximate pH of 3. With cake washing, sugar recovery exceeded 90 percent with asymptotic yield at 15 L wash water/kg insoluble solids.

  7. Development of internal dose assessment procedure for workers in industries using raw materials containing naturally occurring radioactive materials

    International Nuclear Information System (INIS)

    Choi, Cheol Kyu; KIm, Yong Geon; Ji, Seung Woo; Kim, Kwang Pyo; Koo, Bon Cheol; Chang, Byung Uck

    2016-01-01

    It is necessary to assess radiation dose to workers due to inhalation of airborne particulates containing naturally occurring radioactive materials (NORM) to ensure radiological safety required by the Natural Radiation Safety Management Act. The objective of this study is to develop an internal dose assessment procedure for workers at industries using raw materials containing natural radionuclides. The dose assessment procedure was developed based on harmonization, accuracy, and proportionality. The procedure includes determination of dose assessment necessity, preliminary dose estimation, airborne particulate sampling and characterization, and detailed assessment of radiation dose. The developed dose assessment procedure is as follows. Radioactivity concentration criteria to determine dose assessment necessity are 10 Bq·g-1 for 40K and 1 Bq·g-1 for the other natural radionuclides. The preliminary dose estimation is performed using annual limit on intake (ALI). The estimated doses are classified into 3 groups (<0.1 mSv, 0.1-0.3 mSv, and >0.3 mSv). Air sampling methods are determined based on the dose estimates. Detailed dose assessment is performed using air sampling and particulate characterization. The final dose results are classified into 4 different levels (<0.1 mSv, 0.1-0.3 mSv, 0.3-1 mSv, and >1 mSv). Proper radiation protection measures are suggested according to the dose level. The developed dose assessment procedure was applied for NORM industries in Korea, including coal combustion, phosphate processing, and monazite handing facilities. The developed procedure provides consistent dose assessment results and contributes to the establishment of optimization of radiological protection in NORM industries

  8. Placental complications after a previous cesarean section

    OpenAIRE

    Milošević Jelena; Lilić Vekoslav; Tasić Marija; Radović-Janošević Dragana; Stefanović Milan; Antić Vladimir

    2009-01-01

    Introduction The incidence of cesarean section has been rising in the past 50 years. With the increased number of cesarean sections, the number of pregnancies with the previous cesarean section rises as well. The aim of this study was to establish the influence of the previous cesarean section on the development of placental complications: placenta previa, placental abruption and placenta accreta, as well as to determine the influence of the number of previous cesarean sections on the complic...

  9. Development, test and evaluation of a computerized procedure for using Landsat data to estimate spring small grains acreage

    Science.gov (United States)

    Mohler, R. R. J.; Palmer, W. F.; Smyrski, M. M.; Baker, T. C.; Nazare, C. V.

    1982-01-01

    A number of methods which can provide information concerning crop acreages on the basis of a utilization of multispectral scanner (MSS) data require for their implementation a comparatively large amount of labor. The present investigation is concerned with a project designed to improve the efficiency of analysis through increased automation. The Caesar technique was developed to realize this objective. The processability rates of the Caesar procedure versus the historical state-of-the-art proportion estimation procedures were determined in an experiment. Attention is given to the study site, the aggregation technology, the results of the aggregation test, and questions of error characterization. It is found that the Caesar procedure, which has been developed for the spring small grains region of North America, is highly efficient and provides accurate results.

  10. Medical tongue piercing – development and evaluation of a surgical protocol and the perception of procedural discomfort of the participants

    Science.gov (United States)

    2014-01-01

    Background A system providing disabled persons with control of various assistive devices with the tongue has been developed at Aalborg University in Denmark. The system requires an activation unit attached to the tongue with a small piercing. The aim of this study was to establish and evaluate a safe and tolerable procedure for medical tongue piercing and to evaluate the expected and perceived procedural discomfort. Methods Four tetraplegic subjects volunteered for the study. A surgical protocol for a safe insertion of a tongue barbell piercing was presented using sterilized instruments and piercing parts. Moreover, post-procedural observations of participant complications such as bleeding, edema, and infection were recorded. Finally, procedural discomforts were monitored by VAS scores of pain, changes in taste and speech as well as problems related to hitting the teeth. Results The piercings were all successfully inserted in less than 5 min and the pain level was moderate compared with oral injections. No bleeding, infection, embedding of the piercing, or tooth/gingival injuries were encountered; a moderate edema was found in one case without affecting the speech. In two cases the piercing rod later had to be replaced by a shorter rod, because participants complained that the rod hit their teeth. The replacements prevented further problems. Moreover, loosening of balls was encountered, which could be prevented with the addition of dental glue. No cases of swallowing or aspiration of the piercing parts were recorded. Conclusions The procedure proved simple, fast, and safe for insertion of tongue piercings for tetraplegic subjects in a clinical setting. The procedure represented several precautions in order to avoid risks in these susceptible participants with possible co-morbidity. No serious complications were encountered, and the procedure was found tolerable to the participants. The procedure may be used in future studies with tongue piercings being a

  11. European wind turbine testing procedure developments. Task 1: Measurement method to verify wind turbine performance characteristics

    DEFF Research Database (Denmark)

    Hunter, R.; Friis Pedersen, Troels; Dunbabin, P.

    2001-01-01

    There is currently significant standardisation work ongoing in the context of wind farm energy yield warranty assessment and wind turbine power performance testing. A standards maintenance team is revising the current IEC (EN) 61400-12 Ed 1 standard forwind turbine power performance testing...... standard. The work was wide ranging and addressed 'grey' areas of knowledge, regarding existing methodologies or to carry out basic research in support offundamentally new procedures. The work has given rise to recommendations in all areas of the work, including site calibration procedures, nacelle...

  12. 22 CFR 208.610 - What procedures does the U.S. Agency for International Development use in suspension and...

    Science.gov (United States)

    2010-04-01

    ... Principles Relating to Suspension and Debarment Actions § 208.610 What procedures does the U.S. Agency for..., we handle the actions as informally as practicable, consistent with principles of fundamental... International Development use in suspension and debarment actions? 208.610 Section 208.610 Foreign Relations...

  13. The Psychology Department Model Advisement Procedure: A Comprehensive, Systematic Approach to Career Development Advisement

    Science.gov (United States)

    Howell-Carter, Marya; Nieman-Gonder, Jennifer; Pellegrino, Jennifer; Catapano, Brittani; Hutzel, Kimberly

    2016-01-01

    The MAP (Model Advisement Procedure) is a comprehensive, systematic approach to developmental student advisement. The MAP was implemented to improve advisement consistency, improve student preparation for internships/senior projects, increase career exploration, reduce career uncertainty, and, ultimately, improve student satisfaction with the…

  14. The Approach to Development the Human Resources Intellectual Management System. Management Procedures

    OpenAIRE

    Benger, Roman; Antonova, Elena

    2008-01-01

    The Article suggests an approach to designing the Human Resources Intellectual Management System in order to increase Human Resources reliability, using the management methods known from the Theory of Management.. The Article examines the realization of the Subsystem of implementing management methods by the number of management procedures, executing the corresponding management method.

  15. Complex Problem Exercises in Developing Engineering Students' Conceptual and Procedural Knowledge of Electromagnetics

    Science.gov (United States)

    Leppavirta, J.; Kettunen, H.; Sihvola, A.

    2011-01-01

    Complex multistep problem exercises are one way to enhance engineering students' learning of electromagnetics (EM). This study investigates whether exposure to complex problem exercises during an introductory EM course improves students' conceptual and procedural knowledge. The performance in complex problem exercises is compared to prior success…

  16. Powertrain Test Procedure Development for EPA GHG Certification of Medium- and Heavy-Duty Engines and Vehicles

    Energy Technology Data Exchange (ETDEWEB)

    Chambon, Paul H. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Deter, Dean D. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-07-01

    xiii ABSTRACT The goal of this project is to develop and evaluate powertrain test procedures that can accurately simulate real-world operating conditions, and to determine greenhouse gas (GHG) emissions of advanced medium- and heavy-duty engine and vehicle technologies. ORNL used their Vehicle System Integration Laboratory to evaluate test procedures on a stand-alone engine as well as two powertrains. Those components where subjected to various drive cycles and vehicle conditions to evaluate the validity of the results over a broad range of test conditions. Overall, more than 1000 tests were performed. The data are compiled and analyzed in this report.

  17. Development of SCR Aircraft takeoff and landing procedures for community noise abatement and their impact on flight safety

    Science.gov (United States)

    Grantham, W. D.; Smith, P. M.

    1980-01-01

    Piloted simulator studies to determine takeoff and landing procedures for a supersonic cruise transport concept that result in predicted community noise levels which meet current Federal Aviation Administration (FAA) standards are discussed. The results indicate that with the use of advanced procedures, the subject simulated aircraft meets the FAA traded noise levels during takeoff and landing utilizing average flight crew skills. The advanced takeoff procedures developed involved violating three of the current Federal Aviation Regulations (FAR) noise test conditions. These were: (1) thrust cutbacks at altitudes below 214 meters (700 ft); (2) thrust cutback level below those presently allowed; and (3) configuration change, other than raising the landing gear. It was not necessary to violate any FAR noise test conditions during landing approach. It was determined that the advanced procedures developed do not compromise flight safety. Automation of some of the aircraft functions reduced pilot workload, and the development of a simple head-up display to assist in the takeoff flight mode proved to be adequate.

  18. Developing best practices teaching procedures for skinfold assessment: observational examination using the Think Aloud method.

    Science.gov (United States)

    Holmstrup, Michael E; Verba, Steven D; Lynn, Jeffrey S

    2015-12-01

    Skinfold assessment is valid and economical; however, it has a steep learning curve, and many programs only include one exposure to the technique. Increasing the number of exposures to skinfold assessment within an undergraduate curriculum would likely increase skill proficiency. The present study combined observational and Think Aloud methodologies to quantify procedural and cognitive characteristics of skinfold assessment. It was hypothesized that 1) increased curricular exposure to skinfold assessment would improve proficiency and 2) the combination of an observational and Think Aloud analysis would provide quantifiable areas of emphasis for instructing skinfold assessment. Seventy-five undergraduates with varied curricular exposure performed a seven-site skinfold assessment on a test subject while expressing their thoughts aloud. A trained practitioner recorded procedural observations, with transcripts generated from audio recordings to capture cognitive information. Skinfold measurements were compared with a criterion value, and bias scores were generated. Participants whose total bias fell within ±3.5% of the criterion value were proficient, with the remainder nonproficient. An independent-samples t-test was used to compare procedural and cognitive observations across experience and proficiency groups. Additional curricular exposure improved performance of skinfold assessment in areas such as the measurement of specific sites (e.g., chest, abdomen, and thigh) and procedural (e.g., landmark identification) and cognitive skills (e.g., complete site explanation). Furthermore, the Think Aloud method is a valuable tool for determining curricular strengths and weaknesses with skinfold assessment and as a pedagogical tool for individual instruction and feedback in the classroom. Copyright © 2015 The American Physiological Society.

  19. Laparoscopic Ladd procedure in infants: Report of three cases from a developing country

    Directory of Open Access Journals (Sweden)

    Youssef Mohammed

    2008-01-01

    Full Text Available Infants with intestinal malrotation present with bilious emesis and the diagnosis is generally obtained by an upper gastrointestinal barium study. Malrotation is suspected if the ligament of Treitz is not positioned to the left of the vertebral body. Three patients were admitted to our department from March 2006 to May 2007, aged three weeks,one month and eight months, weighing 3,3.200 and 8 kg respectively to whom laparoscopic Ladd′s procedure was done successfully.

  20. Definition, development, and demonstration of analytical procedures for the structured assessment approach. Final report

    International Nuclear Information System (INIS)

    1979-01-01

    Analytical procedures were refined for the Structural Assessment Approach for assessing the Material Control and Accounting systems at facilities that contain special nuclear material. Requirements were established for an efficient, feasible algorithm to be used in evaluating system performance measures that involve the probability of detection. Algorithm requirements to calculate the probability of detection for a given type of adversary and the target set are described

  1. Robotic technology-probably a safe tool for development of completely endoscopic coronary revascularization procedures.

    Science.gov (United States)

    Bonatti, Johannes; Schachner, Thomas; Bonaros, Nikolaos; Rützler, Elisabeth; Weidinger, Felix; Schistek, Roland; Feuchtner, Gudrun; Friedrich, Guy; Pachinger, Otmar; Laufer, Günther

    2008-05-01

    : Totally endoscopic coronary artery bypass grafting (TECAB) requires telemanipulation technologies because attempts using conventional thoracoscopic instrumentation have completely failed. These complex operations require individual and team learning curves and necessitate a stepwise approach. The aim of this study is to assess risk adjusted outcome in robotically assisted coronary artery bypass grafting (CABG) after the first 6 years of application. : From 2001 to 2007, 177 CABG procedures were performed using the da Vinci system. A low risk patient population [age 59 (31-76) years, EuroSCORE 1 (0-7)] was treated. The following procedures were carried out: endoscopic internal mammary artery takedown in minimally invasive direct coronary artery bypass, Off-pump coronary artery bypass, and CABG (n = 26); robotic suturing of left internal mammary artery to left anterior descending artery anastomoses through sternotomy (n = 32); TECAB on the arrested heart (n = 108); TECAB on the beating heart (n = 11). : There was no hospital mortality, and cumulative risk adjusted mortality plots showed that 2.76 predicted events did not occur. Given 177 event free procedures Clopper Pearson estimations revealed a 95% confidence interval between 0.0% and 2.3% for perioperative mortality. : Introduction of robotic TECAB grafting appears to meet current CABG safety standards. Initial application in low risk patients and a stepwise approach towards completely endoscopic versions of the operation are worthwhile. Despite a high grade of innovation and despite learning curves, perioperative mortality may be lower than predicted.

  2. Enhancement of proton beam writing in PMMA through optimization of the development procedure

    International Nuclear Information System (INIS)

    Bolhuis, S.; Kan, J.A. van; Watt, F.

    2009-01-01

    The development step of the proton beam writing (PBW) process plays an important role in the performance characteristics that can be achieved with a resist-developer system. A common developer for PBW in PMMA resist is the mixture IPA/water, used in combination with conventional dip development. In this paper, we investigate the use of the GG-developer, much used in the LIGA-process, and show that the GG-developer is able to dip develop proton beam written structures of feature sizes down to 133 nm in a PMMA layer of 2.4 μm thickness. Moreover, both contrast and sensitivity are found to be higher for the GG-developer compared to dip development in 7:3 IPA/water. The development method as well as the type of developer influences resist development. The effect of megasonic agitation (frequency of 1 MHz) on the development of structures in PMMA was investigated for the developer 7:3 IPA/water. Compared to conventional dip development, structures developed with megasonic agitation showed larger feature sizes, indicating that the development rate was increased. However, performance characteristics were not enhanced: both contrast and sensitivity were found to be lower than after dip development in 7:3 IPA/water.

  3. Procedure for developing biological input for the design, location, or modification of water-intake structures

    Energy Technology Data Exchange (ETDEWEB)

    Neitzel, D.A.; McKenzie, D.H.

    1981-12-01

    To minimize adverse impact on aquatic ecosystems resulting from the operation of water intake structures, design engineers must have relevant information on the behavior, physiology and ecology of local fish and shellfish. Identification of stimulus/response relationships and the environmental factors that influence them is the first step in incorporating biological information in the design, location or modification of water intake structures. A procedure is presented in this document for providing biological input to engineers who are designing, locating or modifying a water intake structure. The authors discuss sources of stimuli at water intakes, historical approaches in assessing potential/actual impact and review biological information needed for intake design.

  4. The development of 126Sn separation procedure by means of TBP resin

    International Nuclear Information System (INIS)

    Andris, Boris; Bena, Jozef

    2016-01-01

    Separation possibilities of 126 Sn with a new extraction-chromatographic material TBP Resin were studied. Suitable conditions for tin separation were determined in hydrochloric acid medium. 126 Sn was concentrated on TBP resin from 6 mol L -1 HCl and was eluted with 0.1 mol L -1 HCl. A purification step to remove 137 Cs with AMP-PAN column was necessary to obtain sufficiently purified samples which were directly measured with gamma spectrometry for 126 Sn activity. Separation of 126 Sn from a raw sludge sample was done according to proposed procedure, 126 Sn was detected and its activity was determined. (author)

  5. Development of a rapid radiochemical procedure for the separation of /sup 235m/U from 239Pu

    International Nuclear Information System (INIS)

    Attrep, M. Jr.; Efurd, D.W.; Roensch, F.R.

    1987-01-01

    We have developed a rapid radiochemical procedure for the isolation and purification of /sup 235m/U (t/sub 1/2/ = 26 minutes) from 239 Pu samples up to 250 mg. Purpose of developing the procedure was to measure the thermal neutron fission cross section of the isomeric meta state of 235 U. We used rapid small-scale anion exchange columns that absorbed uranium in concentrated HBr but did not absorb plutonium. Uranium was easily eluted with very dilute HF. The separation time required 25 to 35 minutes. We were able to attain a separation factor of uranium from plutonium of approximately 1 x 10 10 with samples ranging from 1 x 10 10 to 3 x 10 11 . The ratio of the fission cross sections for the meta to ground state was measured to be 1.42. 4 figs., 1 tab

  6. Use of Formal Procedures in Developing Dialogue Between Operator and Regulator on Radioactive Waste Disposal

    International Nuclear Information System (INIS)

    Yearsley, Roger; Duerden, Susan; Bennett, David

    2001-01-01

    The Environment Agency (the Agency) is responsible, in England and Wales, for authorisation of radioactive waste disposal under the Radioactive Substances Act 1993. British Nuclear Fuels plc (BNFL) is currently authorised to dispose of solid low level radioactive waste at its Drigg site near Sellafield in Cumbria. Drigg is the primary site for the disposal of solid low level radioactive waste generated by the UK nuclear industry. A small facility operated by United Kingdom Atomic Energy Authority (UKAEA) at Dounreay on the north coast of Scotland is used solely for wastes arising on the UKAEA site. Drigg also offers a disposal route for smaller users of radioactive substances, such as hospitals and universities. Significant benefits have been derived from implementing a formal Issue Resolution Procedure as part of a soundly based process for dialogue between the Agency and BNFL. Benefits include improved understanding of the Agency's expectations, which has in turn led to improvements in BNFL's documentation and technical approach. The Agency considers the use of a formal Issue Resolution Procedure has placed the dialogue with BNFL on firm foundations for the planned assessment of the PostClosure Safety Case for Drigg when it is submitted in September 2002

  7. The development of new analysis procedures for reactor internals under pipe breaks

    International Nuclear Information System (INIS)

    Song, Heuy Gap; Jhung, Myung Jo; Chang, Sang Gyun; Lee, Gyu Man

    1993-04-01

    This study investigates the horizontal responses of the reactor internals due to a 14 inch safety injection nozzle break which is expected to cause the largest loads of the branch line pipe breaks defined for the YGN 3 and 4. It examines the effects of two forcing terms, RV motions and internals hydraulic loads, and suggests new procedure which can be used for the tributary pipe break analysis. The analysis result confirms the applicability of suggested procedure to a small size tributary pipe break analysis. Also, this study calculates the horizontal responses of the reactor internals due to a 3 inch pressurizer spray line nozzle break which is the only one remaining in the primary side after leak-before-break evaluation, and secondary side pipe breaks such as main steam line and economizer feedwater line. The responses are compared with those of safe shutdown earthquake(SSE) to show that SSE loads with a conservative margin may be used for the pipe break loads in the preliminary design. (Author)

  8. Remote maintenance systems requirements are being developed to provide design guidelines for machine components, to define maintenance interfaces, and to quantify maintenance equipment and procedures needed

    International Nuclear Information System (INIS)

    Spampinato, P.T.; Tabor, M.A.

    1988-01-01

    Remote maintenance systems requirements are being developed to provide design guidelines for machine components, to define maintenance interfaces, and to quantify maintenance equipment and procedures needed

  9. Development of a VR training system of robotic peroral operation procedure for endoscopic surgery of digestive tracts

    International Nuclear Information System (INIS)

    Suzuki, Naoki; Hattori, Asaki; Tanoue, Kazuo; Ieiri, Satoshi; Konishi, Kozo; Tomikawa, Morimasa; Kenmotsu, Hajime; Hashizume, Makoto

    2010-01-01

    This report presents the development of a VR (virtual real) training system of robotic peroral operation procedure for endoscopic resection of gastric mucosa as the training is essential because the procedure differs from usual one hitherto. For VR operation space, used is reporters' sphere-filled organ model (SFM), which is deformed by and repels to, the outside force as a soft tissue rapidly in the real time. The deformation and repellence are computable. The SFM space is reconstructed to 3D of the inner environment of stomach using MRI data. The endoscope has, at the right and left side of its top, 2 arms of inner needle knife-equipped robotic forceps and is inserted perorally for operation. In VR, the forceps can grab the gastric mucosa, cut it with the knife to complete resection and carry the specimen out of the body. For the procedure training, the time required for hemostasis, bleeding volume, trace of the arms, intensity and direction of the outer force given are recorded, with which trainee's safety and degree of skill are evaluable in VR. Hydration step and clipping to close the wound are to be further added in the procedure. (T.T.)

  10. Co-existence of exfoliation syndrome, previous iris surgery, and heterochromia.

    Science.gov (United States)

    Konstas, A G; Williamson, T H

    1993-12-01

    A case is described where exfoliation syndrome developed in a relatively young patient with heterochromia. The patient had previously undergone large radial iridotomies as part of penetrating keratoplasty procedures. This case illustrates an association between iris surgery and early manifestation of exfoliation syndrome.

  11. 24 CFR 5.380 - Public housing programs: Procedure for development of pet rules.

    Science.gov (United States)

    2010-04-01

    ... for development of pet rules. 5.380 Section 5.380 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development GENERAL HUD PROGRAM REQUIREMENTS; WAIVERS Pet Ownership for the Elderly or Persons With Disabilities Pet Ownership Requirements for Public Housing...

  12. 24 CFR 5.353 - Housing programs: Procedure for development of pet rules.

    Science.gov (United States)

    2010-04-01

    ... development of pet rules. 5.353 Section 5.353 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development GENERAL HUD PROGRAM REQUIREMENTS; WAIVERS Pet Ownership for the Elderly or Persons With Disabilities Pet Ownership Requirements for Housing Programs § 5.353 Housing...

  13. Toxic trace elements in Chilean seafoods; Development of analytical quality control procedures

    Energy Technology Data Exchange (ETDEWEB)

    De Gregori, I.; Delgado, D.; Pinochet, H. (Catholic University of Valparaiso (Chile). Chemical Institute); Gras, N.; Thieck, M.; Munoz, L. (Chilean Nuclear Energy Commission, Nuclear Center La Reina, Santiago (Chile). Neutron Activation Analysis Laboratory); Bruhn, C.; Navarrete, G. (University of Concepcion (Chile). Pharmacy Faculty, Instrumental Analysis Department)

    1992-01-15

    Chile is a well known producer and exporter of shell fish. These seafoods, like other specimens of marine origin, are susceptible to environmental and other contaminations like trace elements, including toxicants. Therefore adequate analytical quality assurance is mandatory before accepting analytical results. In this context, use of at least 2 independent methods of determination and validation with certified reference materials (CRM) provides acceptable criteria for judging the reliability of the data. This paper describes sample treatments and analytical procedures for Cd, Cu and Hg determinations in mollusc samples. Three independent analytical techniques, namely differential pulse anodic stripping voltammetry, neutron activation analysis and atomic absorption spectrometry, were used. CRM standards of the IAEA, NIST and BCR were analyzed to evaluate quality assurance. Following the quality control phase, the concentrations of cadmium, copper, and mercury in fresh and canned mollusc samples Tagelus dombeii and Semelle solida (Navajuelas and Almejas chilenas respectively) from different locations were determined. (author). 32 refs.; 4 figs.; 7 tabs.

  14. Toxic trace elements in Chilean seafoods: development of analytical quality control procedures.

    Science.gov (United States)

    De Gregori, I; Delgado, D; Pinochet, H; Gras, N; Thieck, M; Muñoz, L; Bruhn, C; Navarrete, G

    1992-01-15

    Chile is a well known producer and exporter of shell fish. These seafoods, like other specimens of marine origin, are susceptible to environmental and other contamination by trace elements, including toxicants. Therefore, adequate analytical quality assurance is mandatory before accepting analytical results. In this context, the use of at least two independent methods of determination and validation with certified reference materials (CRM) provides acceptable criteria for judging the reliability of the data. This paper describes sample treatments and analytical procedures for Cd, Cu and Hg determinations in mollusc samples. Three independent analytical techniques, namely differential pulse anodic stripping voltammetry, neutron activation analysis and atomic absorption spectrometry, were used. CRM standards of the IAEA, NIST and BCR were analyzed to evaluate quality assurance. Following the quality control phase, the concentrations of cadmium, copper and mercury in fresh and canned mollusc samples Tagelus dombeii and Semelle solida (Navajuelas and Almejas chilenas respectively) from different locations were determined.

  15. Developing a Noninvasive Procedure Using Labeled Monoclonal Antibody Anti-VEGF (Bevacizumab) for Detection of Endometriosis

    Science.gov (United States)

    Machado, Daniel Escorsim; Perini, Jamila Alessandra; Orlando, Margarida Maria Camoes

    2015-01-01

    The off-label use of bevacizumab labeled with 99mTc as a new radiopharmaceutical for imaging of endometriosis is a promising noninvasive, new clinical procedure. The bevacizumab in monoclonal antibodies targeted at vascular endothelial growth factor (VEGF) is superexpressed in cases of endometriosis. In this study we evaluate the imaging of endometriosis lesion in rats (induced to endometriosis) using bevacizumab-99mTc. The results showed that bevacizumab-99mTc imaged the lesion and support his use for Nuclear Medicine applied to gynecology. Also the results appointed that this radiopharmaceutical has a hepatobiliary excretion. It is important to notice that the dose used was almost 0,01% of the usual dose for the bevacizumab. PMID:26240826

  16. Procedures development and methodology of control for application of good manufacture practices (GMP) on human blood irradiation

    International Nuclear Information System (INIS)

    Boghi, Claudio

    2008-01-01

    The irradiation of human blood is used to avoid the TA-GVHD (transfusion-associated graft-versus-host-disease), a rare but devastating adverse effect of leukocytes present in blood components for a immunocompetent transfusion recipients. Usually this irradiation practice is performed to a physical elimination of leukocytes. The implementation of the procedures will assure that the properly dose in a range of 25 Gy to 50 Gy will be delivered to the blood in the bag collected in a blood tissue bank. The studies of the procedures in order to establish a GMP (Good Manufacturing Practices) were developed under the guidelines of the standard ISO 11137 - Sterilization of health care products - Requirements for validation and routine control - Radiation sterilization. In this work, two dosimetric systems were used for dose mapping during the studies of irradiator qualification, loading pattern, irradiation process validation and auditing. The CaS0 4 :Dy dosimeter presented difficulties concerning to uncertainty on dose measurement, stability, traceability and calibration. The PMMA and Gafchromic dosimetric systems have shown a better performance and were adopted on studies of irradiators qualification that are necessary to implementation of GMP. The irradiation tests have been done in a Gammacell 220 irradiator. The developed procedures can be adapted for different kinds of gamma irradiators, allowing implanting a quality assurance program and a GMP for blood irradiation. (author)

  17. Development of a Nucleic Acid Extraction Procedure for Simultaneous Recovery of DNA and RNA from Diverse Microbes in Water

    Directory of Open Access Journals (Sweden)

    Vincent R. Hill

    2015-05-01

    Full Text Available Drinking and environmental water samples contain a diverse array of constituents that can interfere with molecular testing techniques, especially when large volumes of water are concentrated to the small volumes needed for effective molecular analysis. In this study, a suite of enteric viruses, bacteria, and protozoan parasites were seeded into concentrated source water and finished drinking water samples, in order to investigate the relative performance of nucleic acid extraction techniques for molecular testing. Real-time PCR and reverse transcription-PCR crossing threshold (CT values were used as the metrics for evaluating relative performance. Experimental results were used to develop a guanidinium isothiocyanate-based lysis buffer (UNEX buffer that enabled effective simultaneous extraction and recovery of DNA and RNA from the suite of study microbes. Procedures for bead beating, nucleic acid purification, and PCR facilitation were also developed and integrated in the protocol. The final lysis buffer and sample preparation procedure was found to be effective for a panel of drinking water and source water concentrates when compared to commercial nucleic acid extraction kits. The UNEX buffer-based extraction protocol enabled PCR detection of six study microbes, in 100 L finished water samples from four drinking water treatment facilities, within three CT values (i.e., within 90% difference of the reagent-grade water control. The results from this study indicate that this newly formulated lysis buffer and sample preparation procedure can be useful for standardized molecular testing of drinking and environmental waters.

  18. Development and application of procedures to evaluate air quality and visibility impacts of low-altitude flying operations

    Energy Technology Data Exchange (ETDEWEB)

    Liebsch, E.J.

    1990-08-01

    This report describes the development and application of procedures to evaluate the effects of low-altitude aircraft flights on air quality and visibility. The work summarized in this report was undertaken as part of the larger task of assessing the various potential environmental impacts associated with low-altitude military airspaces. Accomplishing the air quality/visibility analysis for the GEIS included (1) development and application of an integrated air quality model and aircraft emissions database specifically for Military Training Route (MTR) or similar flight operations, (2) selection and application of an existing air quality model to analyze the more widespread and less concentrated aircraft emissions from military Operations Areas (MOAs) and Restricted Areas (RAs), and (3) development and application of procedures to assess impacts of aircraft emissions on visibility. Existing air quality models were considered to be inadequate for predicting ground-level concentrations of pollutants emitted by aircraft along MTRs; therefore, the Single-Aircraft Instantaneous Line Source (SAILS) and Multiple-Aircraft Instantaneous Line Source (MAILS) models were developed to estimate potential impacts along MTRs. Furthermore, a protocol was developed and then applied in the field to determine the degree of visibility impairment caused by aircraft engine exhaust plumes. 19 refs., 2 figs., 3 tabs.

  19. Development of Procedures for the Analysis of Components of Dumped Chemical Weapons and Their Principal Transformation Products in Sea Water

    International Nuclear Information System (INIS)

    Saveleva, E. I.; Koryagina, N. L.; Radilov, A. S.; Khlebnikova, N. S.; Khrustaleva, V. S.

    2007-01-01

    A package of chemical analytical procedures was developed for the detection of products indicative of the presence of damped chemical weapons in the Baltic Sea. The principal requirements imposed upon the procedures were the following: high sensitivity, reliable identification of target compounds, wide range of components covered by survey analysis, and lack of interferences from sea salts. Thiodiglycol, a product of hydrolysis of sulfur mustard reportedly always detected in the sites of damping chemical weapons in the Baltic Sea, was considered the principal marker. We developed a high-sensitivity procedure for the determination of thiodiglycol in sea water, involving evaporation of samples to dryness in a vacuum concentrator, followed by tert-butyldimethylsilylation of the residue and GCMS analysis in the SIM mode with meta-fluorobenzoic acid as internal reference. The detection limit of thiodiglycol was 0.001 mg/l, and the procedure throughput was up to 30 samples per day. The same procedure, but with BSTFA as derivatizing agent instead of MTBSTFA, was used for preparing samples for survey analysis of nonvolatile components. In this case, full mass spectra were measured in the GCMS analysis. The use of BSTFA was motivated by the fact that trimethylsilyl derivatives are much wider represented in electronic mass spectral databases. The identification of sulfur mustard, volatile transformation products of sulfur mustard and lewisite, as well as chloroacetophenone in sea water was performed by means of GCMS in combination with SPME. The survey GC-MS analysis was focused on the identification of volatile and nonvolatile toxic chemicals whose mass spectra are included in the OPCW database (3219 toxic chemicals, precursors, and transformation products) with the use of AMDIS software (version 2.62). Using 2 GC-MS instruments, we could perform the survey analysis for volatile and nonvolatile components of up to 20 samples per day. Thus, the package of three procedures

  20. A PROCEDURAL AND COST ANALYSIS STUDY OF MEDIA IN INSTRUCTIONAL SYSTEMS DEVELOPMENT, PARTS A AND B.

    Science.gov (United States)

    BARSON, JOHN; JONES, GARDNER, M.

    A TWO-PART STUDY WAS CONDUCTED TO IDENTIFY THE FACTORS WHICH CONTRIBUTE TO SUCCESSFUL MEDIA INNOVATION AND INSTRUCTIONAL DEVELOPMENT, AND TO ESTABLISH GUIDELINES TO SERVE OTHERS. IN PART A, THE OPERATION OF MEDIA SUPPORT AGENCIES AT MICHIGAN STATE UNIVERSITY AND THE DEVELOPMENT OF SELECTED COURSES OF STUDY EMPLOYING THE NEWER MEDIA WERE REVIEWED.…

  1. "Heidelberg standard examination" and "Heidelberg standard procedures" - Development of faculty-wide standards for physical examination techniques and clinical procedures in undergraduate medical education.

    Science.gov (United States)

    Nikendei, C; Ganschow, P; Groener, J B; Huwendiek, S; Köchel, A; Köhl-Hackert, N; Pjontek, R; Rodrian, J; Scheibe, F; Stadler, A-K; Steiner, T; Stiepak, J; Tabatabai, J; Utz, A; Kadmon, M

    2016-01-01

    The competent physical examination of patients and the safe and professional implementation of clinical procedures constitute essential components of medical practice in nearly all areas of medicine. The central objective of the projects "Heidelberg standard examination" and "Heidelberg standard procedures", which were initiated by students, was to establish uniform interdisciplinary standards for physical examination and clinical procedures, and to distribute them in coordination with all clinical disciplines at the Heidelberg University Hospital. The presented project report illuminates the background of the initiative and its methodological implementation. Moreover, it describes the multimedia documentation in the form of pocketbooks and a multimedia internet-based platform, as well as the integration into the curriculum. The project presentation aims to provide orientation and action guidelines to facilitate similar processes in other faculties.

  2. Collection of Pyrethroids in Water and Sediment Matrices: Development and Validation of a Standard Operating Procedure

    Science.gov (United States)

    Hladik, Michelle; Orlando, James L.; Kuivila, Kathryn

    2009-01-01

    Loss of pyrethroid insecticides onto surfaces during sample collection can confound the interpretation of analytical and toxicity test results. Sample collection devices, container materials, and water matrix composition have a significant influence on the association of pyrethroids to container walls, which can be as high as 50 percent. Any sample collection method involving transfer through multiple containers or pieces of equipment increases the potential for pyrethroid loss. This loose 'surface-association' with container walls can be reversed through agitation. When sampling water matrices with pumps or autosamplers, no pyrethroids were lost as long as the water was moving continuously through the system. When collecting water matrices in containers, the material with the least amount of pyrethroid sorption is as follows: glass less than (pyrethroids were easier to re-suspend from the glass container walls. Since the amount of surface-association is proportional to the ratio of volume-to-contact-area of the sample, taking larger-volume field samples (greater than 3 liters) reduced pyrethroid losses to less than 10 percent. The amount of surface-association cannot be predicted easily because of the dependence on water matrix composition; samples with higher dissolved organic carbon or suspended-sediment concentrations were observed to have lower percent loss. Sediment samples were not affected by glass-container sorption (the only containers tested). Standardized sample-collection protocols are critical to yield accurate pyrethroid concentrations for assessment of potential effects, and have been summarized in an accompanying standard operating procedure.

  3. Development of the QA/QC Procedures for a Neutron Interrogation System

    Energy Technology Data Exchange (ETDEWEB)

    Obhodas, Jasmina; Sudac, Davorin; Valkovic, Vladivoj [Ruder Boskovic Institute, 10000 Zagreb (Croatia)

    2015-07-01

    In order to perform QA/QC procedures for a system dedicated to the neutron interrogation of objects for the presence of threat materials one needs to perform measurements of reference materials (RM) having the same (or similar) atomic ratios as real materials. It is well known that explosives, drugs, and various other benign materials, contain chemical elements such as hydrogen, oxygen, carbon and nitrogen in distinctly different quantities. For example, a high carbon-to-oxygen ratio (C/O) is characteristic of drugs. Explosives can be differentiated by measurement of both C/O and nitrogen-to-oxygen (N/O) ratios. The C/N ratio of the chemical warfare agents, coupled with the measurement of elements such as fluorine and phosphorus, clearly differentiate them from the conventional explosives. Correlations between theoretical values and experimental results obtained in laboratory conditions for C/O and N/C ratios of simulants of hexogen (RDX), TNT, DLM2, TATP, cocaine, heroin, yperite, tetranitromethane, peroxide methylethyl-ketone, nitromethane and ethyleneglycol dinitrate are presented. (authors)

  4. State and Federal project development procedures for bus rapid transit : managing differences and reducing implementation delays

    Science.gov (United States)

    2011-08-01

    This report documents an investigation into the transportation project development process in the : context of the implementation of bus rapid transit systems on the State Highway System as well as such : systems being part of the Federal New Starts ...

  5. Development of K-Version of the Finite Element Method: A Robust Mathematical and Computational Procedure

    National Research Council Canada - National Science Library

    Reddy, J. N

    2006-01-01

    This report summarizes the research carried out under Grant F49620-03-1-0201 on the development of least-squares based finite element models of viscous compressible and incompressible flows as well...

  6. Development of the NASA VALT digital navigation system. [for approach and landing procedures of VTOL aircraft

    Science.gov (United States)

    Mcconnell, W. J., Jr.; Skutecki, E. R.; Calzado, A. J.

    1975-01-01

    The research to develop and fabricate a terminal area navigation system for use in the NASA VTOL Approach and Landing Technology (VALT) program. The results of that effort are reported. The navigation system developed and fabricated was based on a general purpose airborne digital computer. A set of flight hardware units was fabricated to create the necessary analog, digital and human interface with the computer. A comprehensive package of software was created to implement the control and guidance laws required for automatic and flight director approaches that are curved in two planes. A technique was developed that enables the generation of randomly shaped lateral paths from simple input data. The lateral path concept combines straight line and elliptical-curved segments to fit a continuous curved path to the data points. A simple, fixed base simulation was put together to assist in developing and evaluating the system. The simulation was used to obtain system performance data during simulated curved-path approaches.

  7. Development of new test procedures for measuring fine and coarse aggregates specific gravity.

    Science.gov (United States)

    2009-09-01

    The objective of the research is to develop and evaluate new test methods at determining the specific gravity and absorption of both fine and coarse aggregates. Current methods at determining the specific gravity and absorption of fine and coarse agg...

  8. Development of a versatile procedure for the biofunctionalization of Ti-6Al-4V implants

    Energy Technology Data Exchange (ETDEWEB)

    Rezvanian, Parsa; Arroyo-Hernández, María [Centro de Tecnología Biomédica, Universidad Politécnica de Madrid, 28223 Pozuelo de Alarcón, Madrid (Spain); Departamento de Ciencia de Materiales, ETSI Caminos, Canales y Puertos, Universidad Politécnica de Madrid, 28040 Madrid (Spain); Ramos, Milagros [Centro de Tecnología Biomédica, Universidad Politécnica de Madrid, 28223 Pozuelo de Alarcón, Madrid (Spain); Daza, Rafael; Elices, Manuel; Guinea, Gustavo V. [Centro de Tecnología Biomédica, Universidad Politécnica de Madrid, 28223 Pozuelo de Alarcón, Madrid (Spain); Departamento de Ciencia de Materiales, ETSI Caminos, Canales y Puertos, Universidad Politécnica de Madrid, 28040 Madrid (Spain); Pérez-Rigueiro, José, E-mail: jperez@mater.upm.es [Centro de Tecnología Biomédica, Universidad Politécnica de Madrid, 28223 Pozuelo de Alarcón, Madrid (Spain); Departamento de Ciencia de Materiales, ETSI Caminos, Canales y Puertos, Universidad Politécnica de Madrid, 28040 Madrid (Spain)

    2016-11-30

    Highlights: • Surface of Ti-6Al-4V was functionalized by Activated Vapor Silanization (AVS). • AVS is proven to be a reliable procedure for functionalizing Ti-6Al-4V samples. • The functional layer was characterized by AFM and fluorescence microscopy. • The cytocompatibility of the functionalized samples was assessed by cell cultures. • The stability of the functional layer under physiological conditions was confirmed. - Abstract: Titanium (Ti) and titanium alloys are among the most-commonly used metallic materials for implantation in the human body for the purpose of replacing hard tissue. Although Ti and its alloys are widely used for such an aim, in implants of a long duration they exhibit some shortcomings due to the loosening of the very implant. This phenomenon is highly dependent on the interaction between the organic tissues and the surface of the implant. In this study, the authors introduce a surface treatment technique for functionalization of the surface of Ti-6Al-4V alloy with amino groups that could help to control this interaction. The functionalized layer was deposited by activated vapor silanization (AVS), which has been proven as a reliable and robust technique with other materials. The resulting biofunctional layers were characterized by atomic force microscopy and fluorescence microscopy, with the optimal conditions for the deposition of a homogeneous film with a high density of amino groups being determined. Additionally, the non-toxic nature and stability of the biofunctional layer were confirmed by cell culturing. The results show the formation of a homogeneous biofunctional amine layer on Ti-6Al-4V alloy that may be used as a platform for the subsequent covalent immobilization of proteins or other biomolecules.

  9. Biobanking human endometrial tissue and blood specimens: standard operating procedure and importance to reproductive biology research and diagnostic development.

    Science.gov (United States)

    Sheldon, Elizabeth; Vo, Kim Chi; McIntire, Ramsey A; Aghajanova, Lusine; Zelenko, Zara; Irwin, Juan C; Giudice, Linda C

    2011-05-01

    To develop a standard operating procedure (SOP) for collection, transport, storage of human endometrial tissue and blood samples, subject and specimen annotation, and establishing sample priorities. The SOP synthesizes sound scientific procedures, the literature on ischemia research, sample collection and gene expression profiling, good laboratory practices, and the authors' experience of workflow and sample quality. The National Institutes of Health, University of California, San Francisco, Human Endometrial Tissue and DNA Bank. Women undergoing endometrial biopsy or hysterectomy for nonmalignant indications. Collecting, processing, storing, distributing endometrial tissue and blood samples under approved institutional review board protocols and written informed consent from participating subjects. Standard operating procedure. The SOP addresses rigorous and consistent subject annotation, specimen processing and characterization, strict regulatory compliance, and a reference for researchers to track collection and storage times that may influence their research. The comprehensive and systematic approach to the procurement of human blood and endometrial tissue in this SOP ensures the high quality, reliability, and scientific usefulness of biospecimens made available to investigators by the National Institutes of Health, University of California, San Francisco, Human Endometrial Tissue and DNA Bank. The detail and perspective in this SOP also provides a blueprint for implementation of similar collection programs at other institutions. Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  10. Developing BrightHearts: A Pediatric Biofeedback-Mediated Relaxation App to Manage Procedural Pain and Anxiety.

    Science.gov (United States)

    Morrow, Angela M; Burton, Karen L O; Watanabe, Melissa M; Cloyd, Benjamin H; Khut, George P

    2017-10-27

    The objective of this study was to develop a child-friendly biofeedback-mediated relaxation device called BrightHearts. Qualitative data were collected at a tertiary pediatric hospital to inform an iterative design process. Clinicians participated in expert group interviews to identify practical considerations that would facilitate the use of BrightHearts during procedures and provide feedback on prototype designs. Children 7 to 18 years of age participated in interactive exhibitions of the prototypes and were interviewed about their experiences using BrightHearts. Twenty-four clinicians participated in 6 group interviews. Thirty-nine children participated in interactive exhibitions, and 21 were interviewed. Clinicians placed high value on the following factors in the management of procedural pain: providing children with an element of control, the use of relaxation techniques, and the use of portable electronic devices such as iPads. They highlighted the need for BrightHearts to be cost effective, portable, and capable of engaging children's interest. They confirmed the utility of developing a biofeedback-assisted relaxation device for children. Based on the factors identified by clinicians, BrightHearts was developed as an iPad application (app) paired with a wireless heart rate monitor. The BrightHearts heart rate biofeedback app displays digital geometric artwork that responds to changes in heart rate. Children 7 to 17 years of age understood the concept of biofeedback and operated the app by slowing their heart rates. The BrightHearts app can be used to teach children biofeedback-assisted relaxation. Ongoing studies are evaluating its efficacy for the management of procedural pain in children. © 2017 World Institute of Pain.

  11. Mixing Interviews and Rasch Modeling: Demonstrating a Procedure Used to Develop an Instrument That Measures Trust

    Science.gov (United States)

    David, Shannon L.; Hitchcock, John H.; Ragan, Brian; Brooks, Gordon; Starkey, Chad

    2018-01-01

    Developing psychometrically sound instruments can be difficult, especially if little is known about the constructs of interest. When constructs of interest are unclear, a mixed methods approach can be useful. Qualitative inquiry can be used to explore a construct's meaning in a way that informs item writing and allows the strengths of one analysis…

  12. [Biomagnetism from the neuropsychiatric viewpoint--principles of recent developments in diagnostic procedure].

    Science.gov (United States)

    Kühne, G E; Lemke, S

    1985-04-01

    The following survey is intended to demonstrate and discuss some principle problems of biomagnetism and the application in clinical fields. The development of special technical parameters especially by the SQUID method is initiating new possibilities of research and completing the neurobiologically determinated basis and conditions of neuropsychiatric disorders. The Magnetoencephalography (MEG) will be represent an important role of a new functional diagnostic method.

  13. Procedures for Developing Evidence-Informed Performance Checklists for Improving Early Childhood Intervention Practices

    Science.gov (United States)

    Dunst, Carl J.

    2017-01-01

    A conceptualization-operationalization-measurement framework is described for developing evidence-informed early childhood intervention performance checklists. Performance checklists include lists of practice indicators where the indicators, taken together, operationally define particular types of intervention practices that, when used as…

  14. 76 FR 31887 - Procedures by Which the Agricultural Marketing Service Develops, Revises, Suspends, or Terminates...

    Science.gov (United States)

    2011-06-02

    ... develop and improve standards of quality, condition, quantity, grade, and packaging, and recommend and... CFR part 36). Background: AMS received a petition from the American Frozen Food Institute (AFFI... format consistent with recent revisions of other U.S. grade standards. This format has been designed to...

  15. Logistic regression modelling: procedures and pitfalls in developing and interpreting prediction models

    Directory of Open Access Journals (Sweden)

    Nataša Šarlija

    2017-01-01

    Full Text Available This study sheds light on the most common issues related to applying logistic regression in prediction models for company growth. The purpose of the paper is 1 to provide a detailed demonstration of the steps in developing a growth prediction model based on logistic regression analysis, 2 to discuss common pitfalls and methodological errors in developing a model, and 3 to provide solutions and possible ways of overcoming these issues. Special attention is devoted to the question of satisfying logistic regression assumptions, selecting and defining dependent and independent variables, using classification tables and ROC curves, for reporting model strength, interpreting odds ratios as effect measures and evaluating performance of the prediction model. Development of a logistic regression model in this paper focuses on a prediction model of company growth. The analysis is based on predominantly financial data from a sample of 1471 small and medium-sized Croatian companies active between 2009 and 2014. The financial data is presented in the form of financial ratios divided into nine main groups depicting following areas of business: liquidity, leverage, activity, profitability, research and development, investing and export. The growth prediction model indicates aspects of a business critical for achieving high growth. In that respect, the contribution of this paper is twofold. First, methodological, in terms of pointing out pitfalls and potential solutions in logistic regression modelling, and secondly, theoretical, in terms of identifying factors responsible for high growth of small and medium-sized companies.

  16. General procedure to aid the development of continuous pharmaceutical processes using multivariate statistical modeling - an industrial case study.

    Science.gov (United States)

    Tomba, Emanuele; De Martin, Marialuisa; Facco, Pierantonio; Robertson, John; Zomer, Simeone; Bezzo, Fabrizio; Barolo, Massimiliano

    2013-02-28

    Streamlining the manufacturing process has been recognized as a key issue to reduce production costs and improve safety in pharmaceutical manufacturing. Although data available from earlier developmental stages are often sparse and unstructured, they can be very useful to improve the understanding about the process under development. In this paper, a general procedure is proposed for the application of latent variable statistical methods to support the development of new continuous processes in the presence of limited experimental data. The proposed procedure is tested on an industrial case study concerning the development of a continuous line for the manufacturing of paracetamol tablets. The main driving forces acting on the process are identified and ranked according to their importance in explaining the variability in the available data. This improves the understanding about the process by elucidating how different active pharmaceutical ingredient pretreatments, different formulation modes and different settings on the processing units affect the overall operation as well as the properties of the intermediate and final products. The results can be used as a starting point to perform a comprehensive and science-based quality risk assessment that help to define a robust control strategy, possibly enhanced with the integration of a design space for the continuous process at a later stage. Copyright © 2013 Elsevier B.V. All rights reserved.

  17. DEVELOPING HISTORIC BUILDING INFORMATION MODELLING GUIDELINES AND PROCEDURES FOR ARCHITECTURAL HERITAGE IN IRELAND

    Directory of Open Access Journals (Sweden)

    M. Murphy

    2017-08-01

    Full Text Available Cultural heritage researchers have recently begun applying Building Information Modelling (BIM to historic buildings. The model is comprised of intelligent objects with semantic attributes which represent the elements of a building structure and are organised within a 3D virtual environment. Case studies in Ireland are used to test and develop the suitable systems for (a data capture/digital surveying/processing (b developing library of architectural components and (c mapping these architectural components onto the laser scan or digital survey to relate the intelligent virtual representation of a historic structure (HBIM. While BIM platforms have the potential to create a virtual and intelligent representation of a building, its full exploitation and use is restricted to narrow set of expert users with access to costly hardware, software and skills. The testing of open BIM approaches in particular IFCs and the use of game engine platforms is a fundamental component for developing much wider dissemination. The semantically enriched model can be transferred into a WEB based game engine platform.

  18. Developing Historic Building Information Modelling Guidelines and Procedures for Architectural Heritage in Ireland

    Science.gov (United States)

    Murphy, M.; Corns, A.; Cahill, J.; Eliashvili, K.; Chenau, A.; Pybus, C.; Shaw, R.; Devlin, G.; Deevy, A.; Truong-Hong, L.

    2017-08-01

    Cultural heritage researchers have recently begun applying Building Information Modelling (BIM) to historic buildings. The model is comprised of intelligent objects with semantic attributes which represent the elements of a building structure and are organised within a 3D virtual environment. Case studies in Ireland are used to test and develop the suitable systems for (a) data capture/digital surveying/processing (b) developing library of architectural components and (c) mapping these architectural components onto the laser scan or digital survey to relate the intelligent virtual representation of a historic structure (HBIM). While BIM platforms have the potential to create a virtual and intelligent representation of a building, its full exploitation and use is restricted to narrow set of expert users with access to costly hardware, software and skills. The testing of open BIM approaches in particular IFCs and the use of game engine platforms is a fundamental component for developing much wider dissemination. The semantically enriched model can be transferred into a WEB based game engine platform.

  19. Development of a human reliability analysis procedure for a low power/shutdown probabilistic safety assessment in pressurized light water reactors

    Energy Technology Data Exchange (ETDEWEB)

    Kang, D. I.; Sung, T. Y.; Park, J. H.; Kim, T. W.; Han, S. H.; Kim, K. Y.; Yang, J. E.; Jung, W. D.; Lee, Y. H.; Hwang, M. J.

    1997-09-01

    A human reliability analysis (HRA) procedure is developed for a low power/shutdown probalistic safety assessment (PSA) in pressurized light water reactors. At first, the HRA procedure developed is based on the two major current methods: THERP (technique for human error rate prediction) and SHARP (systematic human action reliability procedure). Then, it focuses on the specific situation of low power and shutdown operation of pressurized light water reactors. Major characteristics of the HRA procedure are as follows; 1) The use of the work sheet developed increase the plausibility and credibility of the quantification process of human actions and enable use to trace easily it. 2) The explicit use of decision tree could partly eliminate the possible subjectiveness in human reliability analyst`s judgement used for HRA. It is expected that the HRA procedure developed allow human reliability analyst to perform a systematic and consistent HRA. (author). 26 refs., 13 tabs., 8 figs.

  20. A Guide for Developing Standard Operating Job Procedures for the Pump Station Process Wastewater Treatment Facility. SOJP No. 3.

    Science.gov (United States)

    Perley, Gordon F.

    This is a guide for standard operating job procedures for the pump station process of wastewater treatment plants. Step-by-step instructions are given for pre-start up inspection, start-up procedures, continuous routine operation procedures, and shut-down procedures. A general description of the equipment used in the process is given. Two…

  1. Development of pre-concentration procedure for the determination of Hg isotope ratios in seawater samples

    International Nuclear Information System (INIS)

    Štrok, Marko; Hintelmann, Holger; Dimock, Brian

    2014-01-01

    Highlights: • The method for the quantitative pre-concentration of Hg from seawater was developed. • First report of Hg isotope ratios in seawater is presented. • A unique mass independent 200 Hg isotope fractionation was observed. • This fractionation has unique potential to distinguish anthropogenic and natural Hg. - Abstract: Hg concentrations in seawater are usually too low to allow direct (without pre-concentration and removal of salt matrix) measurement of its isotope ratios with multicollector-inductively coupled plasma mass spectrometry (MC-ICP-MS). Therefore, a new method for the pre-concentration of Hg from large volumes of seawater was developed. The final method allows for relatively fast (about 2.5 L h −1 ) and quantitative pre-concentration of Hg from seawater samples with an average Hg recovery of 98 ± 6%. Using this newly developed method we determined Hg isotope ratios in seawater. Reference seawater samples were compared to samples potentially impacted by anthropogenic activity. The results show negative mass dependent fractionation relative to the NIST 3133 Hg standard with δ 202 Hg values in the range from −0.50‰ to −1.50‰. In addition, positive mass independent fractionation of 200 Hg was observed for samples from reference sites, while impacted sites did not show significant Δ 200 Hg values. Although the influence of the impacted sediments is limited to the seawater and particulate matter in very close proximity to the sediment, this observation may raise the possibility of using Δ 200 Hg to distinguish between samples from impacted and reference sites

  2. A simple procedure eliminating multiple optimization steps required in developing multiplex PCR reactions

    Energy Technology Data Exchange (ETDEWEB)

    Grondin, V.; Roskey, M.; Klinger, K.; Shuber, T. [Integrated Genetics, Framingham, MA (United States)

    1994-09-01

    The PCR technique is one of the most powerful tools in modern molecular genetics and has achieved widespread use in the analysis of genetic diseases. Typically, a region of interest is amplified from genomic DNA or cDNA and examined by various methods of analysis for mutations or polymorphisms. In cases of small genes and transcripts, amplification of single, small regions of DNA are sufficient for analysis. However, when analyzing large genes and transcripts, multiple PCRs may be required to identify the specific mutation or polymorphism of interest. Ever since it has been shown that PCR could simultaneously amplify multiple loci in the human dystrophin gene, multiplex PCR has been established as a general technique. The properities of multiplex PCR make it a useful tool and preferable to simultaneous uniplex PCR in many instances. However, the steps for developing a multiplex PCR can be laborious, with significant difficulty in achieving equimolar amounts of several different amplicons. We have developed a simple method of primer design that has enabled us to eliminate a number of the standard optimization steps required in developing a multiplex PCR. Sequence-specific oligonucleotide pairs were synthesized for the simultaneous amplification of multiple exons within the CFTR gene. A common non-complementary 20 nucleotide sequence was attached to each primer, thus creating a mixture of primer pairs all containing a universal primer sequence. Multiplex PCR reactions were carried out containing target DNA, a mixture of several chimeric primer pairs and primers complementary to only the universal portion of the chimeric primers. Following optimization of conditions for the universal primer, limited optimization was needed for successful multiplex PCR. In contrast, significant optimization of the PCR conditions were needed when pairs of sequence specific primers were used together without the universal sequence.

  3. Time Synchronization Prototype, Server Upgrade Procedure Support and Remote Software Development

    Science.gov (United States)

    Sanders, Shania R.

    2014-01-01

    Networks are roadways of communication that connect devices. Like all roadways, there are rules and regulations that govern whatever (information in this case) travels along them. One type of rule that is commonly used is called a protocol. More specifically, a protocol is a standard that specifies how data should be transmitted over a network. The project outlined in this document seeks to implement one protocol in particular, Precision Time Protocol, within the Kennedy Ground Control Subsystem network at Kennedy Space Center. This document also summarizes work completed for server upgrades, remote software developer training and how all three assignments demonstrated the importance of accountability and security.

  4. Development of an asphalt aging procedure to assess long-term binder performance

    KAUST Repository

    Juristyarini, Pramitha

    2011-09-07

    Nine asphalts, including seven Strategic Highway Research Program asphalts and two Texas asphalts, were aged at several conditions of temperature and oxygen pressure to develop an aging test. Values for a dynamic shear rheometer function, a combination of both elastic and viscous properties that serves as an indicator of susceptibility to age-related pavement cracking, were measured for both aged and unaged samples. Each aging condition was ranked and calibrated against environmental room aging (60°C, 1 atm air), used to simulate road aging. PAV thin-film aging at 90°C, 20 atm air for 32 hr best represented environmental room aging. © Taylor & Francis Group, LLC.

  5. Development of procedures for the identification of human papilloma virus DNA fragments in laser plume

    Science.gov (United States)

    Woellmer, Wolfgang; Meder, Tom; Jappe, Uta; Gross, Gerd; Riethdorf, Sabine; Riethdorf, Lutz; Kuhler-Obbarius, Christina; Loening, Thomas

    1996-01-01

    For the investigation of laser plume for the existence of HPV DNA fragments, which possibly occur during laser treatment of virus infected tissue, human papillomas and condylomas were treated in vitro with the CO2-laser. For the sampling of the laser plume a new method for the trapping of the material was developed by use of water-soluble gelatine filters. These samples were analyzed with the polymerase chain reaction (PCR) technique, which was optimized in regard of the gelatine filters and the specific primers. Positive PCR results for HPV DNA fragments up to the size of a complete oncogene were obtained and are discussed regarding infectiousity.

  6. Development of a biamperometric procedure for the determination of saccharin in dietary products

    OpenAIRE

    Assumpção, Mônica H. M. T.; Medeiros, Roberta Antigo; Madi, Alexandro; Fatibello-Filho, Orlando

    2008-01-01

    In this work was developed a method for the determination of saccharin in dietary products by a biamperometric titration, using two silver electrodes as working electrodes and silver nitrate as titrant. It were used products as juices (light) and sweeteners with saccharin in concentrations ranged from 8.73 x 10-5 mol L-1 to 1.0 x 10-2 mol L-1, and the results were in close agreement with those data found using a HPLC method at a confidence level of 95%. The main advantages of the proposed met...

  7. Research on the development of advanced system safety assessment procedures (3)

    International Nuclear Information System (INIS)

    Suzuki, Kazuhiko

    2005-02-01

    For the safety of chemical plants, safety design based on the concept of independent protection layers (IPLs) has been introduced in chemical/oil refinery industries. Risk assessment support system is proposed to integrate safety design environment to apply it to ISA (Integrated Safety Assessment) for Nuclear Reprocessing Facilities. In abnormal situations operators have to make sequential important and strategic task and decisions; (ex. Interpreting sensor information, defining cause/consequence and target states, deciding corrective actions) considering a large amount of process information within very limited time. We have developed HAZOP and Maintenance database which has optimum architecture to utilize safety information for operator support. Operator decision support system based on database is implemented by using Microsoft Access. The Computer-aided HAZOP system has been applied to Nuclear Reprocessing Facilities. However, it also became clear that the disadvantages are difficulty in developing models for analyzing the detailed information about equipments in plants. In this report, structure on models have been improved to apply practical plants. We have successfully applied the system to the Nuclear Reprocessing Facilities. (author)

  8. Development of pre-concentration procedure for the determination of Hg isotope ratios in seawater samples.

    Science.gov (United States)

    Štrok, Marko; Hintelmann, Holger; Dimock, Brian

    2014-12-03

    Hg concentrations in seawater are usually too low to allow direct (without pre-concentration and removal of salt matrix) measurement of its isotope ratios with multicollector-inductively coupled plasma mass spectrometry (MC-ICP-MS). Therefore, a new method for the pre-concentration of Hg from large volumes of seawater was developed. The final method allows for relatively fast (about 2.5Lh(-1)) and quantitative pre-concentration of Hg from seawater samples with an average Hg recovery of 98±6%. Using this newly developed method we determined Hg isotope ratios in seawater. Reference seawater samples were compared to samples potentially impacted by anthropogenic activity. The results show negative mass dependent fractionation relative to the NIST 3133 Hg standard with δ(202)Hg values in the range from -0.50‰ to -1.50‰. In addition, positive mass independent fractionation of (200)Hg was observed for samples from reference sites, while impacted sites did not show significant Δ(200)Hg values. Although the influence of the impacted sediments is limited to the seawater and particulate matter in very close proximity to the sediment, this observation may raise the possibility of using Δ(200)Hg to distinguish between samples from impacted and reference sites. Copyright © 2014 Elsevier B.V. All rights reserved.

  9. Research and development on procedures to stabilize acaricides in livestock dips. Proceedings of a final research co-ordination meeting

    International Nuclear Information System (INIS)

    1997-11-01

    Ticks and mites are serious ectoparasites of livestock in many countries. As vectors of animal diseases they pose a threat to livestock production. Traditionally, different types of acaricides are used to control them. One of the most commonly used tick control techniques is to force animals to walk through an acaricide suspension in a trough or Cattle Dip. Dipping is quite effective as the entire body of the animal gets treated with the acaricide. However, with increased usage the concentration of the acaricide in the 'dip' declines due to removal by the animal and degradation by biological and chemicals processes. The dissipation of the acaricide results in loss of efficacy of the 'dip', and may also enhance the development of resistance by the ectoparasites to the acaricides. Maintenance of an effective concentration, by periodic recharge or stabilization of the acaricide, is essential to assure efficient and cost-effective control and to minimize chances of resistance to develop. In 1990, the FAO/IAEA Joint Division, recognizing the need for co-ordinated research on studying the dissipation of acaricides in cattle dips and developing procedures to stabilize them, established a 5-year Co-ordinated Research Programme on Development of Procedures to Stabilize Acaricides in Livestock Dips and of Simplified Methods to Measure Their Concentration, Using Nuclear Techniques. In initiating this programme, the Joint Division recognized that major gaps exist in the knowledge in this area which, if filled, would greatly aid developing countries in their effort to more effectively use acaricides to protect animal health. This TECDOC reports the accomplishments of this programme

  10. Are impact assessment procedures actually promoting sustainable development? Institutional perspectives on barriers and opportunities found in the Swedish committee system

    International Nuclear Information System (INIS)

    Nykvist, Bjoern; Nilsson, Mans

    2009-01-01

    Impact assessment frameworks are gaining increasing attention as a procedure to integrate sustainability concerns in European and national policy-making. The gap between political visions on sustainable development and the reality of policy-making is, however, still pronounced, and a very limited range and scope of available assessment methods are used in practice. This study examines why this pattern prevails, in this case within the Swedish Committees of Inquiry, with a focus on institutional factors determining the function of Impact Assessments. The findings suggest that assessment procedures have little value when not accompanied by clear specific instructions on priorities. A range of institutional constraints emerge in the interface between policy makers and knowledge providers in committees. Dominant professional, organisational, and disciplinary cultures constrain the assessment, and socio-economic priorities are by tradition most important. Based on our analysis, we conclude that to enhance the potential for integrating sustainability concerns, it seems less fruitful to develop more advanced and complex assessment frameworks and models than strengthening institutional arenas for social learning. Such arenas should be; defined by a broad mandate and instructions, characterised by key personal skills and resources, and build institutional capacity for a range of stakeholders to engage with them

  11. Research on the development of advanced system safety assessment procedures. 2

    International Nuclear Information System (INIS)

    Suzuki, Kazuhiko

    2004-02-01

    The past research reports in the area of safety engineering proposed the Computer-aided HAZOP system to be applied to Nuclear Reprocessing Facilities. Automated HAZOP system has great advantage compared with human analysts in terms of accuracy of the results, and time required to conduct HAZOP studies. However, it also became clear that the disadvantages are difficulty in analyzing the detailed information about a substance and a reaction peculiar to each plant or a process. And the outputted results may contain excess and deficiency compared with the HAZOP results performed by specialists. To improve HAZOP System, function of interventions by human is added to the system. Database-Bridge, which applies information management technology such as SQL operation, Query, is developed to perform intervention function. As the result the HAZOP system can give appropriate measures information to protect accidents to uses. Such HAZOP data is applied to safety management of Nuclear Reprocessing Facilities. (author)

  12. Development of the calibration transfer procedures for the XRF analyser AF-20

    CERN Document Server

    Kowalska, E

    2001-01-01

    Two standardization techniques; Direct (DS) and Picewise Direct Standardization (PDS) were applied to multivariate models developed using x-ray spectra. The data were obtained for the determination of Ca and fe in flying ash from brown coal using low resolution XRF analysis. The analyser AF-20 was used with an argon proportional counter and a Cd-109 radioisotope source. Number and comparison of samples from the calibration set were selected. Root mean square error of prediction (RMSEPr) was used as a criterion for assessment of the standardization quality. The best performance was obtained for the PDS method using 5 samples chosen with the leverage method. The RMSEPr value was 4 times lower for Ca determination and 2 times lower for Fe compared with the results without standardization. Software package was designed for fast computation of the standardization transform. The program can be used when the instrument parameters have changed as well as for calibration of the new instrument.

  13. Comparative assessment of supervision and decision-making procedures regarding sustainable development

    International Nuclear Information System (INIS)

    Carlevaro, F.; Garbely, M.; Genoud, S.

    2002-01-01

    This final report for the Swiss Federal Office of Energy (SFOE) presents the results of a study made on the possibilities of establishing a system of indicators that allows the monitoring of sustainable development and its effects, as stipulated in the Agenda 21. The report presents the findings of the study on criteria and indicators for sustainability in the energy area. The challenge posed by the synthesis of information from a system of indicators is discussed and four general approaches are proposed, compared and tested for the monitoring of sustainability in the energy area. These include the calculation of a composite index from several indicators, a similar process that uses statistical methods of dimensional reduction, methods for the measurement of productivity loaned from economics and a method for decision-making using multiple criteria. Examples for the four approaches are given and experience gained in their use - partly in other countries and in United Nations agencies - is discussed

  14. Image Processing of Welding Procedure Specification and Pre-process program development for Finite Element Modelling

    International Nuclear Information System (INIS)

    Kim, K. S.; Lee, H. J.

    2009-11-01

    PRE-WELD program, which generates automatically the input file for the finite element analysis on the 2D butt welding at the dissimilar metal weld part, was developed. This program is pre-process program of the FEM code for analyzing the residual stress at the welding parts. Even if the users have not the detail knowledge for the FEM modelling, the users can make the ABAQUS INPUT easily by inputting the shape data of welding part, the weld current and voltage of welding parameters. By using PRE-WELD program, we can save the time and the effort greatly for preparing the ABAQUS INPUT for the residual stress analysis at the welding parts, and make the exact input without the human error

  15. Developing Ultra-small Scale Mechanical Testing Methods and Microstructural Investigation Procedures for Irradiated Materials

    Energy Technology Data Exchange (ETDEWEB)

    Hosemann, Peter; Kaoumi, Djamel

    2018-04-02

    Nuclear materials are an essential aspect of nuclear engineering. While great effort is spent on designing more advanced reactors or enhancing a reactor’s safety, materials have been the bottleneck of most new developments. The designs of new reactor concepts are driven by neutronic and thermodynamic aspects, leading to unusual coolants (liquid metal, liquid salt, gases), higher temperatures, and higher radiation doses than conventional light water reactors have. However, any (nuclear) engineering design must consider the materials used in the anticipated application in order to ever be realized. Designs which may look easy, simple and efficient considering thermodynamics or neutronic aspects can show their true difficulty in the materials area, which then prevents them from being deployed. In turn, the materials available are influencing the neutronic and thermodynamic designs and therefore must be considered from the beginning, requiring close collaborations between different aspects of nuclear engineering. If a particular design requires new materials, the licensing of the reactor must be considered, but licensing can be a costly and time consuming process that results in long lead times to realize true materials innovation. Extensive materials evaluation and irradiation campaigns need to be conducted in order to introduce a new material in a nuclear system. For licensing purposes, standard materials testing is key. However, basic scientific studies on new materials or even already used materials have the potential to accelerate the process of materials development or foster predictability of materials that are already in service and therefore are essential in order not to face difficulties later in the development or service stage. Therefore a combination of engineering scale materials evaluation as well as basic scientific understanding of the materials property changes under service condition is key to address potential issues in the process. Ion

  16. Development of opto-mechanical tools and procedures for the new generation of RICH-detectors at CERN

    CERN Document Server

    Laub, M; Ullaland, O

    2001-01-01

    This thesis is focused on development of opto-mechanical tools and procedures, which would contribute to the achievement of the best possible performance of new Ring Imaging Cherenkov (RICH) detectors. On the base of requirements, given by the physics objective of the LHCb detector, and an analysis of the detector opto-mechanical system, specifications of individual opto-mechanical components were determined. Spherical mirrors, planar mirrors and mirror adjustable mounts were the components of interest. Next, their parameters to be characterised were defined. Possible measurement methods were studied and relevant set ups based on suitable methods were developed. Meanwhile, available modern metrology technologies, like laser operated instruments or digital image processing, were applied with an attempt to innovate them and to increase their achievable performance limits. When applicable, the set ups were automated in order to make the measurements fast and reliable. An optical laboratory, devoted to the charac...

  17. OIE philosophy, policy and procedures for the development of food safety standards.

    Science.gov (United States)

    Droppers, W F G L

    2006-08-01

    Food safety was identified as a high priority area in the 2001-2005 World Organisation for Animal Health (OIE) Strategic Plan. Member Countries of the OIE considered that the organisation should be more active in issues of public health and consumer protection and that this should include more involvement in the area of diseases or pathogens transmissible through food, whether or not animals are affected by such diseases or pathogens. A permanent Working Group on Animal Production Food Safety was established in 2002 to coordinate the OIE's activities in food safety. The Working Group was requested to focus on food safety measures applicable at farm level and to monitor the ongoing cooperation between the OIE and Codex Alimentarius. More emphasis is now placed on the public health aspects of a disease when OIE standards are developed or revised. For example, the revised chapter on bovine tuberculosis in the Terrestrial Animal Health Code includes food safety recommendations for meat and meat products and for milk and milk products. The revised chapter was approved by the OIE International Committee of Member Countries at their 73rd General Session in May 2005. More chapters will follow, beginning with a chapter addressing bovine brucellosis.

  18. Maize sugary enhancer1 (se1) is a presence-absence variant of a previously uncharacterized gene and development of educational videos to raise the profile of plant breeding and improve curricula

    Science.gov (United States)

    Haro von Mogel, Karl J.

    Carbohydrate metabolism is a biologically, economically, and culturally important process in crop plants. Humans have selected many crop species such as maize (Zea mays L.) in ways that have resulted in changes to carbohydrate metabolic pathways, and understanding the underlying genetics of this pathway is therefore exceedingly important. A previously uncharacterized starch metabolic pathway mutant, sugary enhancer1 (se1), is a recessive modifier of sugary1 (su1) sweet corn that increases the sugar content while maintaining an appealing creamy texture. This allele has been incorporated into many sweet corn varieties since its discovery in the 1970s, however, testing for the presence of this allele has been difficult. A genetic stock was developed that allowed the presence of se1 to be visually scored in segregating ears, which were used to genetically map se1 to the deletion of a single gene model located on the distal end of the long arm of chromosome 2. An analysis of homology found that this gene is specific to monocots, and the gene is expressed in the endosperm and developing leaf. The se1 allele increased water soluble polysaccharide (WSP) and decreased amylopectin in maize endosperm, but there was no overall effect on starch content in mature leaves due to se1. This discovery will lead to a greater understanding of starch metabolism, and the marker developed will assist in breeding. There is a present need for increased training for plant breeders to meet the growing needs of the human population. To raise the profile of plant breeding among young students, a series of videos called Fields of Study was developed. These feature interviews with plant breeders who talk about what they do as plant breeders and what they enjoy about their chosen profession. To help broaden the education of students in college biology courses, and assist with the training of plant breeders, a second video series, Pollination Methods was developed. Each video focuses on one or two

  19. Environmental procedures

    International Nuclear Information System (INIS)

    1992-01-01

    The European Bank has pledged in its Agreement to place environmental management at the forefront of its operations to promote sustainable economic development in central and eastern Europe. The Bank's environmental policy is set out in the document titled, Environmental Management: The Bank's Policy Approach. This document, Environmental Procedures, presents the procedures which the European Bank has adopted to implement this policy approach with respect to its operations. The environmental procedures aim to: ensure that throughout the project approval process, those in positions of responsibility for approving projects are aware of the environmental implications of the project, and can take these into account when making decisions; avoid potential liabilities that could undermine the success of a project for its sponsors and the Bank; ensure that environmental costs are estimated along with other costs and liabilities; and identify opportunities for environmental enhancement associated with projects. The review of environmental aspects of projects is conducted by many Bank staff members throughout the project's life. This document defines the responsibilities of the people and groups involved in implementing the environmental procedures. Annexes contain Environmental Management: The Bank's Policy Approach, examples of environmental documentation for the project file and other ancillary information

  20. A novel surrogate lung material for impact studies: Development and testing procedures.

    Science.gov (United States)

    Parsa, H; Karac, A; Ivankovic, A

    2017-10-03

    This work focuses on the development of a surrogate lung material (SLM) that reproduces the dynamic response of a human lung under various loading conditions and also allows for the analysis of the extent and distribution of damage. The SLM consists of polyurethane foam used to mimic the spongy lung tissue and fluid-filled gelatine microcapsules used to simulate the damage of alveoli. The bursting pressure of the microcapsules was investigated by conducting low and high rate compression tests on single microcapsules. A bursting pressure of around 5bar was measured which is comparable to the reported lung overpressure at injury level. Low and high rate compression tests were conducted on the SLMs. From the measured mechanical properties and mass density, the stress wave speed was calculated and found to be well in the range of the reported values for human lungs (16-70m/s). In order to study the extent and distribution of damage in the SLMs, as represented by burst microcapsules, a CT scan analysis was carried out before and after the impacts. The CT scan results clearly demonstrated the magnitude and distribution of damage within the specimen. The results are then compared to the Bowen curves, the most often used criteria for predicting blast injuries in humans. An excellent agreement was found between the observed damage in the surrogate lungs and the expected damage in real human lungs. In general, the SLM showed similar stress wave speed, bursting pressure and damage to that of the real lungs. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Meso-scale testing and development of test procedures to maintain mass balance.

    Science.gov (United States)

    Bonner, James; Page, Cheryl; Fuller, Chris

    2003-01-01

    The Conrad Blucher Institute for Surveying and Science (Texas A&M University--Corpus Christi) has conducted numerous petroleum experiments at the Shoreline Environmental Research Facility (Corpus Christi, Texas, USA). The meso-scale facility has multiple wave tanks, permitting some control in experimental design of the investigations, but allowing for real-world conditions. This paper outlines the evolution of a materials balance approach in conducting petroleum experiments at the facility. The first attempt at a materials balance was during a 1998 study on the fate/effects of dispersant use on crude oil. Both water column and beach sediment samples were collected. For the materials balance, the defined environmental compartments for oil accumulation were sediments, water column, and the water surface, while the discharge from the tanks was presumed to be the primary sink. The "lessons learned" included a need to quantify oil adhesion to the tank surfaces. This was resolved by adhering strips of the polymer tank lining to the tank sides that could be later removed and extracted for oil. Also, a protocol was needed to quantify any floating oil on the water surface. A water surface (oil slick) quantification protocol was developed, involving the use of solid-phase extraction disks. This protocol was first tested during a shoreline cleaner experiment, and later refined in subsequent dispersant effectiveness studies. The effectiveness tests were designed to simulate shallow embayments which created the need for additional adjustments in the tanks. Since dispersant efficacy is largely affected by hydrodynamics, it was necessary to scale the hydrodynamic conditions of the tanks to those expected in our prototype system (Corpus Christi Bay, Texas). The use of a scaled model permits the experiment to be reproduced and/or evaluated under different conditions. To minimize wave reflection in the tank, a parabolic wave dissipater was built. In terms of materials balance, this

  2. An actor-oriented transfer perspective on high school students’ development of the use of procedures to solve problems on “rate of change”.

    NARCIS (Netherlands)

    Roorda, Gerrit; Goedhart, Martin; Vos, Pauline

    2015-01-01

    This article reports on a longitudinal observation study about students’ development in their use of procedures to calculate instantaneous rate of change. Different procedures for solving tasks on rate of change are taught in mathematics and physics classes, and together they form a repertoire. Our

  3. Development of a procedure for the multi-element determination of trace elements in wine by ICP-MS

    Energy Technology Data Exchange (ETDEWEB)

    Castineira, M.M.; Brandt, R.; von Bohlen, A.; Jakubowski, N. [Institut fuer Spektrochemie und Angewandte Spektroskopie e.V., Dortmund (Germany)

    2001-07-01

    An inductively coupled plasma mass spectrometric (ICP-MS) procedure has been developed for the determination of trace elements in wine. The procedure consists in simple 1+1 dilution of the wine and semi-quantitative analysis (without external calibration) using In as internal standard. Thirty-one elements at concentrations ranging from 0.1 mg mL{sup -1} to 0.5 ng mL{sup -1} can be determined by ICP-MS analysis with and without digestion. It was investigated whether a matrix effect observed for EtOH in the wine matrix can be overcome by application of a micro-concentric nebulizer with a membrane desolvator (MCN 6000). The results obtained for the MCN 6000 are compared with those obtained by use of a conventional Meinhard nebulizer. It is shown that the observed matrix effect can only be compensated by use of an internal standard for the Meinhard nebulizer, but not for the MCN 6000. Results for ICP-MS are compared with those obtained by total reflection X-ray fluorescence spectrometry (TXRF). (orig.)

  4. Accurate monitoring developed by EDF for FA-3-EPRTM and UK-EPRTM: chemistry-radiochemistry design and procedures

    International Nuclear Information System (INIS)

    Tigeras, Arancha; Bouhrizi, Sofia; Pierre, Marine; L'Orphelin, Jean-Matthieu

    2012-09-01

    The monitoring of chemistry and radiochemistry parameters is a fundamental need in nuclear power plants in order to ensure: - The reactivity control in real time, - The barrier integrity surveillance by means of the fuel cladding failures detection and the primary-pressure boundary components control, - The water quality to limit the radiation build-up and the material corrosion permitting to prepare the maintenance, radioprotection and waste operations. - The efficiency of treatment systems and hence the minimization of chemical and radiochemical substances discharges The relevant chemistry and radiochemistry parameters to be monitored are selected depending on the chemistry conditioning of systems, the source term evaluations, the corrosion mechanisms and the radioactivity consequences. In spite of the difficulties for obtaining representative samples under all circumstances, the EPR M design provides the appropriate provisions and analytical procedures for ensuring the reliable and accurate monitoring of parameters in compliance with the specification requirements. The design solutions, adopted for Flamanville 3-EPR M and UK-EPR M , concerning the sampling conditions and locations, the on-line and analytical equipment, the procedures and the results transmission to control room and chemistry laboratory are supported by ALARP considerations, international experience and researches concerning the nuclides behavior (corrosion product and actinides solubility, fission product degassing, impurities and additives reactions also). This paper details the means developed by EDF for making successful and meaningful sampling and measurements to achieve the essential objectives associated with the monitoring. (authors)

  5. DEVELOPMENT AND TESTING OF PROCEDURES FOR CARRYING OUT EMERGENCY PHYSICAL INVENTORY TAKING AFTER DETECTING ANOMALY EVENTS CONCERNING NM SECURITY

    International Nuclear Information System (INIS)

    VALENTE, J.; FISHBONE, L.

    2003-01-01

    In the State Scientific Center of Russian Federation - Institute of Physics and Power Engineering (SSC RF-IPPE, Obninsk), which is under Minatom jurisdiction, the procedures for carrying out emergency physical inventory taking (EPIT) were developed and tested in cooperation with the Brookhaven National Laboratory (USA). Here the emergency physical inventory taking means the PIT, which is carried out in case of symptoms indicating a possibility of NM loss (theft). Such PIT often requires a verification of attributes and quantitative characteristics for all the NM items located in a specific Material Balance Area (MBA). In order to carry out the exercise, an MBA was selected where many thousands of NM items containing highly enriched uranium are used. Three clients of the computerized material accounting system (CMAS) are installed in this MBA. Labels with unique (within IPPE site) identification numbers in the form of digit combinations and an appropriate bar code have been applied on the NM items, containers and authorized locations. All the data to be checked during the EPIT are stored in the CMAS database. Five variants of anomalies initiating EPIT and requiring different types of activities on EPIT organization are considered. Automatic working places (AWP) were created on the basis of the client computers in order to carry out a large number of measurements within a reasonable time. In addition to a CMAS client computer, the main components of an AWP include a bar-code reader, an electronic scale and an enrichment meter with NaI--detector--the lMCA Inspector (manufactured by the Canberra Company). All these devices work together with a client computer in the on-line mode. Special computer code (Emergency Inventory Software-EIS) was developed. All the algorithms of interaction between the operator and the system, as well as algorithms of data exchange during the measurements and data comparison, are implemented in this software. Registration of detected

  6. Development of analytical procedures for the determination of hexavalent chromium in corrosion prevention coatings used in the automotive industry.

    Science.gov (United States)

    Séby, F; Castetbon, A; Ortega, R; Guimon, C; Niveau, F; Barrois-Oudin, N; Garraud, H; Donard, O F X

    2008-05-01

    The European directive 2000/53/EC limits the use of Cr(VI) in vehicle manufacturing. Although a maximum of 2 g of Cr(VI) was authorised per vehicle for corrosion prevention coatings of key components, since July 2007 its use has been prohibited except for some particular applications. Therefore, the objective of this work was to develop direct analytical procedures for Cr(VI) determination in the different steel coatings used for screws. Instead of working directly with screws, the optimisation of the procedures was carried out with metallic plates homogeneously coated to improve the data comparability. Extraction of Cr(VI) from the metallic parts was performed by sonication. Two extraction solutions were tested: a direct water extraction solution used in standard protocols and an ammonium/ammonia buffer solution at pH 8.9. The extracts were further analysed for Cr speciation by high-performance liquid chromatography (HPLC) inductively coupled plasma (ICP) atomic emission spectrometry or HPLC ICP mass spectrometry depending on the concentration level. When possible, the coatings were also directly analysed by solid speciation techniques (X-ray photoelectron spectroscopy, XPS, and X-ray absorption near-edge structure, XANES) for validation of the results. Very good results between the different analytical approaches were obtained for the sample of coating made up of a heated paint containing Zn, Al and Cr when using the extracting buffer solution at pH 8.9. After a repeated four-step extraction procedure on the same portion test, taking into account the depth of the surface layer reached, good agreement with XPS and XANES results was obtained. In contrast, for the coatings composed of an alkaline Zn layer where Cr(VI) and Cr(III) are deposited, only the extraction procedure using water allowed the detection of Cr(VI). To elucidate the Cr(VI) reduction during extraction at pH 8.9, the reactivity of Cr(VI) towards different species of Zn generally present in the

  7. The role of motor memory in action selection and procedural learning: insights from children with typical and atypical development

    Directory of Open Access Journals (Sweden)

    Jessica Tallet

    2015-07-01

    Full Text Available Motor memory is the process by which humans can adopt both persistent and flexible motor behaviours. Persistence and flexibility can be assessed through the examination of the cooperation/competition between new and old motor routines in the motor memory repertoire. Two paradigms seem to be particularly relevant to examine this competition/cooperation. First, a manual search task for hidden objects, namely the C-not-B task, which allows examining how a motor routine may influence the selection of action in toddlers. The second paradigm is procedural learning, and more precisely the consolidation stage, which allows assessing how a previously learnt motor routine becomes resistant to subsequent programming or learning of a new – competitive – motor routine. The present article defends the idea that results of both paradigms give precious information to understand the evolution of motor routines in healthy children. Moreover, these findings echo some clinical observations in developmental neuropsychology, particularly in children with Developmental Coordination Disorder. Such studies suggest that the level of equilibrium between persistence and flexibility of motor routines is an index of the maturity of the motor system.

  8. [Placental complications after a previous cesarean section].

    Science.gov (United States)

    Milosević, Jelena; Lilić, Vekoslav; Tasić, Marija; Radović-Janosević, Dragana; Stefanović, Milan; Antić, Vladimir

    2009-01-01

    The incidence of cesarean section has been rising in the past 50 years. With the increased number of cesarean sections, the number of pregnancies with the previous cesarean section rises as well. The aim of this study was to establish the influence of the previous cesarean section on the development of placental complications: placenta previa, placental abruption and placenta accreta, as well as to determine the influence of the number of previous cesarean sections on the complication development. The research was conducted at the Clinic of Gynecology and Obstetrics in Nis covering 10-year-period (from 1995 to 2005) with 32358 deliveries, 1280 deliveries after a previous cesarean section, 131 cases of placenta previa and 118 cases of placental abruption. The experimental groups was presented by the cases of placenta previa or placental abruption with prior cesarean section in obstetrics history, opposite to the control group having the same conditions but without a cesarean section in medical history. The incidence of placenta previa in the control group was 0.33%, opposite to the 1.86% incidence after one cesarean section (pcesarean sections and as high as 14.28% after three cesarean sections in obstetric history. Placental abruption was recorded as placental complication in 0.33% pregnancies in the control group, while its incidence was 1.02% after one cesarean section (pcesarean sections. The difference in the incidence of intrapartal hysterectomy between the group with prior cesarean section (0.86%) and without it (0.006%) shows a high statistical significance (pcesarean section is an important risk factor for the development of placental complications.

  9. Modernization of a programmable scanning device used to develop remote inspection procedures related to the nondestructive examination of nuclear components

    International Nuclear Information System (INIS)

    Alencar, Donizete A.; Silva Junior, Silverio F.; Viana, Sadraque S.; Alves, Michel R.C.; Horta, Thamyris C.R.

    2011-01-01

    At CDTN's nondestructive test laboratory there is an electromechanical probe scanning device. That equipment is an important tool used in the development of procedures to be applied in remote inspections of nuclear equipment and components. In order to adequate its functionality an update was planned and executed. Keeping its excellent existing mechanical parts and DC motors, the original electronic power supply and the control unit was replaced by a new one. Furthermore, trajectory control and data processing algorithms were implemented by means of National Instruments LabVIEW 8.6 programming tool. So, both trajectory control and data acquisition/plotting systems were integrated as PC executable software. This paper presents details of the whole process, including the updated hardware, some screen shots showing the trajectory control program and a typical data presentation window. (author)

  10. Modernization of a programmable scanning device used to develop remote inspection procedures related to the nondestructive examination of nuclear components

    Energy Technology Data Exchange (ETDEWEB)

    Alencar, Donizete A.; Silva Junior, Silverio F., E-mail: daa@cdtn.b, E-mail: silvasf@cdtn.b [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil); Viana, Sadraque S.; Alves, Michel R.C.; Horta, Thamyris C.R. [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Dept. de Engenharia Eletronica

    2011-07-01

    At CDTN's nondestructive test laboratory there is an electromechanical probe scanning device. That equipment is an important tool used in the development of procedures to be applied in remote inspections of nuclear equipment and components. In order to adequate its functionality an update was planned and executed. Keeping its excellent existing mechanical parts and DC motors, the original electronic power supply and the control unit was replaced by a new one. Furthermore, trajectory control and data processing algorithms were implemented by means of National Instruments LabVIEW 8.6 programming tool. So, both trajectory control and data acquisition/plotting systems were integrated as PC executable software. This paper presents details of the whole process, including the updated hardware, some screen shots showing the trajectory control program and a typical data presentation window. (author)

  11. Response to the independent technical review of the UMTRA Project procedures and practices for well drilling and development

    International Nuclear Information System (INIS)

    1994-07-01

    This report is a response to the findings and recommendations contained in the ITR report. The text of this document summarizes each ITR finding and recommendation, presents the TAC response, and concludes that implementation of many of the recommendations would benefit the UMTRA Project. Implementation of the recommendations represents ongoing improvement to the TAC well installation and development procedures and will result, in lower overall project costs. Appendix B is an implementation plan that groups similar or complementary action items, provides a schedule for implementation, identifies the group or people responsible for the changes, and estimates hours to implement the changes. The four major action items are as follows: (1) ITR Reevaluation, (2) Well Installation SOP Review and Revision, (3) Well Installation Contract Review and Revision, and (4) TAC and DOE Communications Improvement. The hours listed to implement the improvements are intended to be estimates for budgeting and planning purposes for the remainder of this fiscal year and the upcoming fiscal year

  12. Response to the independent technical review of the UMTRA Project procedures and practices for well drilling and development

    Energy Technology Data Exchange (ETDEWEB)

    1994-07-01

    This report is a response to the findings and recommendations contained in the ITR report. The text of this document summarizes each ITR finding and recommendation, presents the TAC response, and concludes that implementation of many of the recommendations would benefit the UMTRA Project. Implementation of the recommendations represents ongoing improvement to the TAC well installation and development procedures and will result, in lower overall project costs. Appendix B is an implementation plan that groups similar or complementary action items, provides a schedule for implementation, identifies the group or people responsible for the changes, and estimates hours to implement the changes. The four major action items are as follows: (1) ITR Reevaluation, (2) Well Installation SOP Review and Revision, (3) Well Installation Contract Review and Revision, and (4) TAC and DOE Communications Improvement. The hours listed to implement the improvements are intended to be estimates for budgeting and planning purposes for the remainder of this fiscal year and the upcoming fiscal year.

  13. Development of Procedures for Assessing the Impact of Vocational Education Research and Development on Vocational Education (Project IMPACT). Volume 8--A Field Study of Predicting Impact of Research and Development Projects in Vocational and Technical Education.

    Science.gov (United States)

    Malhorta, Man Mohanlal

    As part of Project IMPACT's effort to identify and develop procedures for complying with the impact requirements of Public Law 94-482, a field study was conducted to identify and validate variables and their order of importance in predicting and evaluating impact of research and development (R&D) projects in vocational and technical education.…

  14. Isotopic and other techniques for organic micronutrient analysis and development of quality assurance procedures. Report of a consultants meeting

    International Nuclear Information System (INIS)

    2001-01-01

    between expert and non-expert laboratories for vitamin A/carotenoids, folate, and other B vitamins; (iii) circulate existing food and biological CRMs and other QC material to existing and new networks of laboratories in developing countries for the analysis of vitamin A/carotenoids, folate, and other B vitamins; (iv) develop accessible/inexpensive control materials for these vitamins; (v) develop isotopically labeled reference materials (isolates and intrinsically labeled foods) for use in bioavailability studies and (vi) develop appropriate LC-MS procedures for vitamin A/carotenoids and folates in regional centers. (author)

  15. Obtaining of CD34+ cells from healthy blood donors: development of a rapid and efficient procedure using leukoreduction filters.

    Science.gov (United States)

    Peytour, Yann; Guitart, Amélie; Villacreces, Arnaud; Chevaleyre, Jean; Lacombe, Francis; Ivanovic, Zoran; Praloran, Vincent

    2010-10-01

    Human CD34+ cells are mandatory to study many aspects of human hematopoiesis. Their low frequency in blood or marrow and ethical reasons limit their obtainment in large quantities. Leukoreduction filters (LRFs) are discarded after preparation of red blood cells. The CD34+ cell concentration in healthy donor blood is low (1×10(3) -4×10(3) /mL), but their number trapped in one LRF after filtration of 400 to 450mL of blood is high (0.4×10(6) -1.6×10(6) ). To develop a procedure allowing obtainment of purified CD34+ cells from LRFs with a good yield, white blood cell (WBC) recoveries after a 500-mL continuous or after sequential elution (50- or 20-mL fractions) were compared. Different WBC and mononuclear cell (MNC) centrifugation methods were tested to minimize their PLT contamination before the CD34+ cell immunomagnetic selection. Cell functionality was finally analyzed under various culture conditions. The 20-mL back-flushing of LRFs allowed the most efficient WBC recovery. The next steps (110×g centrifugation, MNC separation on Ficoll, and washes) resulted in a cell suspension in which the lymphocyte recovery was approximately 76±10% and the PLT contamination below 1.6%. After immunomagnetic selection, 4×10(5) to 6×10(5) cells containing approximately 85% of functional CD34+ cells were obtained. This procedure allows the easy, rapid (Blood Banks.

  16. Development of an isotope dilution GC-MS procedure for the routine determination of creatinine in complex serum samples.

    Science.gov (United States)

    Fernández-Fernández, Mario; González-Antuña, Ana; Rodríguez-González, Pablo; Añón Álvarez, M Elena; Álvarez, Francisco V; García Alonso, J Ignacio

    2014-04-20

    The accurate determination of creatinine in serum is essential for the diagnosis and treatment of kidney diseases. The determination of serum creatinine in clinical laboratories is routinely carried out by the Jaffe method or by enzymatic methods that may suffer from interferences. So, the development of reliable, fast and interference-free routine methods for complex serum samples is required. A fast method using isotope dilution mass spectrometry (IDMS) and gas chromatography mass spectrometry (GC-MS) was developed using minimally (13)C labeled creatinine analogs, multiple linear regression and rapid derivatization of creatinine with acetylacetone in 2 min by using focused microwave technology. The proposed method was validated with the analyses of two Certified Reference Materials (ERM-DA252a and ERM-DA253a) and compared with the Jaffe and enzymatic methods when analyzing real serum samples containing variable levels of bilirubin The proposed method is capable of providing accurate serum creatinine concentrations in less than 45 min from sample arrival to full data treatment and can be an alternative routine procedure for creatinine determinations in complex serum samples. Copyright © 2014 Elsevier B.V. All rights reserved.

  17. Rapid fish stock depletion in previously unexploited seamounts: the ...

    African Journals Online (AJOL)

    Rapid fish stock depletion in previously unexploited seamounts: the case of Beryx splendens from the Sierra Leone Rise (Gulf of Guinea) ... A spectral analysis and red-noise spectra procedure (REDFIT) algorithm was used to identify the red-noise spectrum from the gaps in the observed time-series of catch per unit effort by ...

  18. Identification of potential participant scientists and development of procedures for a national inventory of selected biological monitoring programs: a mail questionnaire survey

    Energy Technology Data Exchange (ETDEWEB)

    Kemp, H.T.; Goff, F.G.; Ross, J.W.

    1978-03-01

    Procedural details of how the National Biological Monitoring Inventory was conducted are described. Results of a nationwide telephone campaign to identify principal investigators and also of a nationwide questionnaire mailing to the investigators identified are presented. On the basis of percentage of questionnaire returns (nearly 50 percent), the Inventory was judged to be successful. The communication procedures, guidelines, and formats developed may be useful to others engaged in this type of research.

  19. Scoring Writing Samples in Educational Research: Selecting and Developing an Appropriate Procedure for Evaluating Elementary Student Writing.

    Science.gov (United States)

    Hawk, Anne W.; Cross, James Logan

    This study involved the selection and adaptation of a writing assessment procedure for teachers and researchers in the Duval County Public Schools (Florida) to use in assessing changes in writing ability among elementary grade students. Through a review of the literature, four writing assessment procedures (analytic, holistic, focused holistic,…

  20. A Guide for Developing Standard Operating Job Procedures for the Grit Removal Process Wastewater Treatment Facility. SOJP No. 2.

    Science.gov (United States)

    Deal, Gerald A.; Montgomery, James A.

    This guide describes standard operating job procedures for the grit removal process of wastewater treatment plants. Step-by-step instructions are given for pre-start up inspection, start-up, continuous operation, and shut-down procedures. A description of the equipment used in the process is given. Some theoretical material is presented. (BB)

  1. Indiscriminate behaviors in previously institutionalized young children.

    Science.gov (United States)

    Gleason, Mary Margaret; Fox, Nathan A; Drury, Stacy S; Smyke, Anna T; Nelson, Charles A; Zeanah, Charles H

    2014-03-01

    This study included 54-month-old children with a history of institutional care. Our goal was to: (1) examine differences in indiscriminate social behaviors in children with a history of institutional care compared with home-reared children; (2) test whether foster care reduces indiscriminate social behaviors in a randomized controlled trial; and (3) examine early predictors of indiscriminate behaviors. Participants were 58 children with a history of institutional care and 31 never-institutionalized control (NIG) subjects enrolled in a randomized controlled trial of foster care for institutional care, assessed from toddlerhood to 54 months. Indiscriminate social behaviors were measured naturalistically by using the Stranger at the Door procedure. In the Stranger at the Door procedure, children with a history of institutional care left with a stranger at higher rates than NIG subjects (33% vs. 3.5%; P Children in the care as usual group left more than NIG subjects (41.9% vs. 3.6%; P ≤ .001). The differences between the foster care group (24.1%) and the care as usual group and between foster care group and NIG were not significant. In a logistic regression, early disorganized attachment behaviors, baseline developmental quotient, and caregiving quality after randomization contributed to variance at 54 months. In the same analysis using only children with a history of institutional care, only disorganized attachment contributed significantly to 54-month indiscriminate social behaviors (Exp[B] = 1.6 [95% confidence interval: 1.1-2.5]). Observed socially indiscriminate behaviors at 54 months were associated with prolonged exposure to institutional care. Young children raised in conditions of deprivation who fail to develop organized attachments as toddlers are at increased risk for subsequent indiscriminate behaviors.

  2. A non-linear procedure for the numerical analysis of crack development in beams failing in shear

    Directory of Open Access Journals (Sweden)

    P. Bernardi

    2016-01-01

    Full Text Available In this work, a consistent formulation for the representation of concrete behavior before and after cracking has been implemented into a non-linear model for the analysis of reinforced concrete structures, named 2D-PARC. Several researches have indeed pointed out that the adoption of an effective modeling for concrete, combined with an accurate failure criterion, is crucial for the correct prediction of the structural behavior, not only in terms of failure load, but also with reference to a realistic representation of crack initiation and development. This last aspect is particularly relevant at serviceability conditions in order to verify the fulfillment of structural requirements provided by Design Codes, which limit the maximum crack width due to appearance and durability issues. In more details, a constitutive model originally proposed by Ottosen and based on non-linear elasticity has been here incorporated into 2D-PARC in order to improve the numerical efficiency of the adopted algorithm, providing at the same time an accurate prediction of the structural response. The effectiveness of this procedure has been verified against significant experimental results available in the technical literature and relative to reinforced concrete beams without stirrups failing in shear, which represent a problem of great theoretical and practical importance in the field of structural engineering. Numerical results have been compared to experimental evidences not only in terms of global structural response (i.e. applied load vs. midspan deflection, but also in terms of crack pattern evolution and maximum crack widths.

  3. Development of an engineering design process and associated systems and procedures for a UK geological disposal facility - 59160

    International Nuclear Information System (INIS)

    Rendell, Philip; Breen, Brendan; Clark, Alastair; Reece, Steve; O'Grady, Henry

    2012-01-01

    implemented for the identification, capture, analysis, update, verification, validation and acceptance of requirements for the GDF. This is to ensure that there are traceable links between requirements, and to identify and record the verification/ validation of individual requirements. This paper describes the engineering design process and the supporting documents, systems and procedures. The paper addresses the relationship to the geological disposal programme timeline in 'Geological Disposal - Steps towards implementation' and, from there, to the UK Government 'Managing Radioactive Waste Safely' Programme. It also describes the next steps in the development of the design process, and some of the lessons learnt to date. (authors)

  4. Crown lengthening procedures

    Directory of Open Access Journals (Sweden)

    AA. Khoshkhonejad

    1994-06-01

    Full Text Available Nowadays, due to recent developments and researches in dental science, it is possible to preserve and restore previously extracted cases such as teeth with extensive caries, fractured or less appropriate cases for crown coverage as well as teeth with external perforation caused by restorative pins. In order to restore the teeth with preservation of periodontium, we should know thoroughly physiological aspects of periodontium and protection of Biologic Width which is formed by epithelial and supracrestal connective tissue connections. Considering biologic width is one of the principal rules of teeth restoration, otherwise we may destruct periodontal tissues. Several factors are involved in placing a restoration and one of the most important ones is where the restoration margin is terminated. Many studies have been conducted on the possible effects of restoration margin on the gingiva and due to the results of these studies it was concluded that restoration margin should be finished supragingivally. However, when we have to end the restoration under Gingival Crest, First a healthy gingival sulcus is required. Also, we should not invade the biological width. Since a normal biologic with is reported 2 mm and sound tooth tissue should be placed at least 2 mm coronal to the epithelial tissue, the distance between sound tooth tissue and crown margin should be at least 4mm. Thus, performing crown lengthening is essential to increase the clinical crown length. Basically, two objectives are considered: 1 restorative 2 esthetic (gummy smile Surgical procedure includes gingivectomy and flap procedure. Orthodontic procedure involves orthodontic extrusion or force eruption technique which is controlled vertical movements of teeth into occlusion. Besides, this procedure can also used to extrude teeth defects from the gingival tissue. By crown lengthening, tooth extraction is not required and furthermore, adjacent teeth preparation for placing a fixed

  5. Development and operation of a quality assurance system for deviations from standard operating procedures in a clinical cell therapy laboratory.

    Science.gov (United States)

    McKenna, D; Kadidlo, D; Sumstad, D; McCullough, J

    2003-01-01

    Errors and accidents, or deviations from standard operating procedures, other policy, or regulations must be documented and reviewed, with corrective actions taken to assure quality performance in a cellular therapy laboratory. Though expectations and guidance for deviation management exist, a description of the framework for the development of such a program is lacking in the literature. Here we describe our deviation management program, which uses a Microsoft Access database and Microsoft Excel to analyze deviations and notable events, facilitating quality assurance (QA) functions and ongoing process improvement. Data is stored in a Microsoft Access database with an assignment to one of six deviation type categories. Deviation events are evaluated for potential impact on patient and product, and impact scores for each are determined using a 0- 4 grading scale. An immediate investigation occurs, and corrective actions are taken to prevent future similar events from taking place. Additionally, deviation data is collectively analyzed on a quarterly basis using Microsoft Excel, to identify recurring events or developing trends. Between January 1, 2001 and December 31, 2001 over 2500 products were processed at our laboratory. During this time period, 335 deviations and notable events occurred, affecting 385 products and/or patients. Deviations within the 'technical error' category were most common (37%). Thirteen percent of deviations had a patient and/or a product impact score > or = 2, a score indicating, at a minimum, potentially affected patient outcome or moderate effect upon product quality. Real-time analysis and quarterly review of deviations using our deviation management program allows for identification and correction of deviations. Monitoring of deviation trends allows for process improvement and overall successful functioning of the QA program in the cell therapy laboratory. Our deviation management program could serve as a model for other laboratories in

  6. Implant breast reconstruction after salvage mastectomy in previously irradiated patients.

    Science.gov (United States)

    Persichetti, Paolo; Cagli, Barbara; Simone, Pierfranco; Cogliandro, Annalisa; Fortunato, Lucio; Altomare, Vittorio; Trodella, Lucio

    2009-04-01

    The most common surgical approach in case of local tumor recurrence after quadrantectomy and radiotherapy is salvage mastectomy. Breast reconstruction is the subsequent phase of the treatment and the plastic surgeon has to operate on previously irradiated and manipulated tissues. The medical literature highlights that breast reconstruction with tissue expanders is not a pursuable option, considering previous radiotherapy a contraindication. The purpose of this retrospective study is to evaluate the influence of previous radiotherapy on 2-stage breast reconstruction (tissue expander/implant). Only patients with analogous timing of radiation therapy and the same demolitive and reconstructive procedures were recruited. The results of this study prove that, after salvage mastectomy in previously irradiated patients, implant reconstruction is still possible. Further comparative studies are, of course, advisable to draw any conclusion on the possibility to perform implant reconstruction in previously irradiated patients.

  7. Partial updating of clinical practice guidelines often makes more sense than full updating: a systematic review on methods and the development of an updating procedure.

    Science.gov (United States)

    Becker, Monika; Neugebauer, Edmund A M; Eikermann, Michaela

    2014-01-01

    To conduct a systematic review of the methods used to determine when and how to update clinical practice guidelines (CPGs) and develop a procedure for updating CPGs. We searched MEDLINE, Embase, and the Cochrane Methodology Register for methodological publications on updating CPGs. Guideline development manuals were obtained from the Web sites of guideline-developing organizations. Using the information obtained from these records, a procedure for updating CPGs was developed. A total of 5,116 journal articles were screened, and seven articles met the criteria for inclusion. Forty-seven manuals were included; of these, eight included details about the methods used to update the guidelines. Most of the included publications focused on assessing whether the CPGs needed updating and not on how to update them. The developed procedure includes a systematic monitoring system and a scheduled process for updating the CPGs, which includes guidance on how to determine the type and scope of an update. Partial updating often makes more sense than updating the whole CPG because topics and recommendations differ in terms of the need for updating. Guideline developers should implement a systematic updating procedure that includes an ongoing monitoring system that is appropriate for the nature of the guideline topics and the capabilities of the developers. Copyright © 2014 Elsevier Inc. All rights reserved.

  8. A unified framework for developing effective hygiene procedures for hands, environmental surfaces and laundry in healthcare, domestic, food handling and other settings

    Directory of Open Access Journals (Sweden)

    Bloomfield, Sally F.

    2017-06-01

    Full Text Available Hygiene procedures for hands, surfaces and fabrics are central to preventing spread of infection in settings including healthcare, food production, catering, agriculture, public settings, and home and everyday life. They are used in situations including hand hygiene, clinical procedures, decontamination of environmental surfaces, respiratory hygiene, food handling, laundry hygiene, toilet hygiene and so on. Although the principles are common to all, approaches currently used in different settings are inconsistent. A concern is the use of inconsistent terminology which is misleading, especially to people we need to communicate with such as the public or cleaning professionals.This paper reviews the data on current approaches, alongside new insights to developing hygiene procedures. Using this data, we propose a more scientifically-grounded framework for developing procedures that maximize protection against infection, based on consistent principles and terminology, and applicable across all settings.A key feature is use of test models which assess the state of surfaces after treatment rather than product performance alone. This allows procedures that rely on removal of microbes to be compared with those employing chemical or thermal inactivation. This makes it possible to ensure that a consistent “safety target level” is achieved regardless of the type of procedure used, and allows us deliver maximum health benefit whilst ensuring prudent usage of antimicrobial agents, detergents, water and energy.

  9. Spectrophotometric determination of uranium with arsenazo previous liquid-liquid extraction and colour development in organic medium; Determinacion espectrofotometrica de uranio con arsenazo, previa extraccion y desarrollo del color en medio organico

    Energy Technology Data Exchange (ETDEWEB)

    Palomares Delgado, F.; Vera Palomino, J.; Petrement Eguiluz, J. C.

    1964-07-01

    The determination of uranium with arsenazo is hindered by a great number of cation which form stable complexes with the reactive and may given rise to serious interferences. By studying the optimum conditions of uranium the extraction be means of tributylphosphate solutions dissolved in methylisobuthylketone, under conditions for previous masking of the interfering cations, an organic extract was obtained containing all the uranium together with small amounts of iron. The possible interference derived from the latter element is avoided by reduction with hydroxylammoniumchlorid followed by complex formation of the Fe(II)-ortophenantroline compound in alcoholic medium. (Author) 17 refs.

  10. Quantization Procedures

    International Nuclear Information System (INIS)

    Cabrera, J. A.; Martin, R.

    1976-01-01

    We present in this work a review of the conventional quantization procedure, the proposed by I.E. Segal and a new quantization procedure similar to this one for use in non linear problems. We apply this quantization procedures to different potentials and we obtain the appropriate equations of motion. It is shown that for the linear case the three procedures exposed are equivalent but for the non linear cases we obtain different equations of motion and different energy spectra. (Author) 16 refs

  11. Field Laboratory in the Osage Reservation -- Determination of the Status of Oil and Gas Operations: Task 1. Development of Survey Procedures and Protocols

    Energy Technology Data Exchange (ETDEWEB)

    Carroll, Herbert B.; Johnson, William I.

    1999-04-27

    Procedures and protocols were developed for the determination of the status of oil, gas, and other mineral operations on the Osage Mineral Reservation Estate. The strategy for surveying Osage County, Oklahoma, was developed and then tested in the field. Two Osage Tribal Council members and two Native American college students (who are members of the Osage Tribe) were trained in the field as a test of the procedures and protocols developed in Task 1. Active and inactive surface mining operations, industrial sites, and hydrocarbon-producing fields were located on maps of the county, which was divided into four more or less equal areas for future investigation. Field testing of the procedures, protocols, and training was successful. No significant damage was found at petroleum production operations in a relatively new production operation and in a mature waterflood operation.

  12. Local recurrence risk after previous salvage mastectomy.

    Science.gov (United States)

    Tanabe, M; Iwase, T; Okumura, Y; Yoshida, A; Masuda, N; Nakatsukasa, K; Shien, T; Tanaka, S; Komoike, Y; Taguchi, T; Arima, N; Nishimura, R; Inaji, H; Ishitobi, M

    2016-07-01

    Breast-conserving surgery is a standard treatment for early breast cancer. For ipsilateral breast tumor recurrence (IBTR) after breast-conserving surgery, salvage mastectomy is the current standard surgical procedure. However, it is not rare for patients with IBTR who have received salvage mastectomy to develop local recurrence. In this study, we examined the risk factors of local recurrence after salvage mastectomy for IBTR. A total of 118 consecutive patients who had histologically confirmed IBTR without distant metastases and underwent salvage mastectomy without irradiation for IBTR between 1989 and 2008 were included from eight institutions in Japan. The risk factors of local recurrence were assessed. The median follow-up period from salvage mastectomy for IBTR was 4.6 years. Patients with pN2 or higher on diagnosis of the primary tumor showed significantly poorer local recurrence-free survival than those with pN0 or pN1 at primary tumor (p mastectomy for IBTR. Further research and validation studies are needed. (UMIN-CTR number UMIN000008136). Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. Human factoring administrative procedures

    International Nuclear Information System (INIS)

    Grider, D.A.; Sturdivant, M.H.

    1991-01-01

    In nonnuclear business, administrative procedures bring to mind such mundane topics as filing correspondence and scheduling vacation time. In the nuclear industry, on the other hand, administrative procedures play a vital role in assuring the safe operation of a facility. For some time now, industry focus has been on improving technical procedures. Significant efforts are under way to produce technical procedure requires that a validated technical, regulatory, and administrative basis be developed and that the technical process be established for each procedure. Producing usable technical procedures requires that procedure presentation be engineered to the same human factors principles used in control room design. The vital safety role of administrative procedures requires that they be just as sound, just a rigorously formulated, and documented as technical procedures. Procedure programs at the Tennessee Valley Authority and at Boston Edison's Pilgrim Station demonstrate that human factors engineering techniques can be applied effectively to technical procedures. With a few modifications, those same techniques can be used to produce more effective administrative procedures. Efforts are under way at the US Department of Energy Nuclear Weapons Complex and at some utilities (Boston Edison, for instance) to apply human factors engineering to administrative procedures: The techniques being adapted include the following

  14. Micro-computed tomography-based phenotypic approaches in embryology: procedural artifacts on assessments of embryonic craniofacial growth and development

    Directory of Open Access Journals (Sweden)

    Logan C Cairine

    2010-02-01

    Full Text Available Abstract Background Growing demand for three dimensional (3D digital images of embryos for purposes of phenotypic assessment drives implementation of new histological and imaging techniques. Among these micro-computed tomography (μCT has recently been utilized as an effective and practical method for generating images at resolutions permitting 3D quantitative analysis of gross morphological attributes of developing tissues and organs in embryonic mice. However, histological processing in preparation for μCT scanning induces changes in organ size and shape. Establishing normative expectations for experimentally induced changes in size and shape will be an important feature of 3D μCT-based phenotypic assessments, especially if quantifying differences in the values of those parameters between comparison sets of developing embryos is a primary aim. Toward that end, we assessed the nature and degree of morphological artifacts attending μCT scanning following use of common fixatives, using a two dimensional (2D landmark geometric morphometric approach to track the accumulation of distortions affecting the embryonic head from the native, uterine state through to fixation and subsequent scanning. Results Bouin's fixation reduced average centroid sizes of embryonic mouse crania by approximately 30% and substantially altered the morphometric shape, as measured by the shift in Procrustes distance, from the unfixed state, after the data were normalized for naturally occurring shape variation. Subsequent μCT scanning produced negligible changes in size but did appear to reduce or even reverse fixation-induced random shape changes. Mixtures of paraformaldehyde + glutaraldehyde reduced average centroid sizes by 2-3%. Changes in craniofacial shape progressively increased post-fixation. Conclusions The degree to which artifacts are introduced in the generation of random craniofacial shape variation relates to the degree of specimen dehydration during the

  15. Micro-computed tomography-based phenotypic approaches in embryology: procedural artifacts on assessments of embryonic craniofacial growth and development.

    Science.gov (United States)

    Schmidt, Eric J; Parsons, Trish E; Jamniczky, Heather A; Gitelman, Julian; Trpkov, Cvett; Boughner, Julia C; Logan, C Cairine; Sensen, Christoph W; Hallgrímsson, Benedikt

    2010-02-17

    Growing demand for three dimensional (3D) digital images of embryos for purposes of phenotypic assessment drives implementation of new histological and imaging techniques. Among these micro-computed tomography (microCT) has recently been utilized as an effective and practical method for generating images at resolutions permitting 3D quantitative analysis of gross morphological attributes of developing tissues and organs in embryonic mice. However, histological processing in preparation for microCT scanning induces changes in organ size and shape. Establishing normative expectations for experimentally induced changes in size and shape will be an important feature of 3D microCT-based phenotypic assessments, especially if quantifying differences in the values of those parameters between comparison sets of developing embryos is a primary aim. Toward that end, we assessed the nature and degree of morphological artifacts attending microCT scanning following use of common fixatives, using a two dimensional (2D) landmark geometric morphometric approach to track the accumulation of distortions affecting the embryonic head from the native, uterine state through to fixation and subsequent scanning. Bouin's fixation reduced average centroid sizes of embryonic mouse crania by approximately 30% and substantially altered the morphometric shape, as measured by the shift in Procrustes distance, from the unfixed state, after the data were normalized for naturally occurring shape variation. Subsequent microCT scanning produced negligible changes in size but did appear to reduce or even reverse fixation-induced random shape changes. Mixtures of paraformaldehyde + glutaraldehyde reduced average centroid sizes by 2-3%. Changes in craniofacial shape progressively increased post-fixation. The degree to which artifacts are introduced in the generation of random craniofacial shape variation relates to the degree of specimen dehydration during the initial fixation. Fixation methods that

  16. Induced vaginal birth after previous caesarean section

    Directory of Open Access Journals (Sweden)

    Akylbek Tussupkaliyev

    2016-11-01

    Full Text Available Introduction The rate of operative birth by Caesarean section is constantly rising. In Kazakhstan, it reaches 27 per cent. Research data confirm that the percentage of successful vaginal births after previous Caesarean section is 50–70 per cent. How safe the induction of vaginal birth after Caesarean (VBAC remains unclear. Methodology The studied techniques of labour induction were amniotomy of the foetal bladder with the vulsellum ramus, intravaginal administration of E1 prostaglandin (Misoprostol, and intravenous infusion of Oxytocin-Richter. The assessment of rediness of parturient canals was conducted by Bishop’s score; the labour course was assessed by a partogram. The effectiveness of labour induction techniques was assessed by the number of administered doses, the time of onset of regular labour, the course of labour and the postpartum period and the presence of complications, and the course of the early neonatal period, which implied the assessment of the child’s condition, described in the newborn development record. The foetus was assessed by medical ultrasound and antenatal and intranatal cardiotocography (CTG. Obtained results were analysed with SAS statistical processing software. Results The overall percentage of successful births with intravaginal administration of Misoprostol was 93 per cent (83 of cases. This percentage was higher than in the amniotomy group (relative risk (RR 11.7 and was similar to the oxytocin group (RR 0.83. Amniotomy was effective in 54 per cent (39 of cases, when it induced regular labour. Intravenous oxytocin infusion was effective in 94 per cent (89 of cases. This percentage was higher than that with amniotomy (RR 12.5. Conclusions The success of vaginal delivery after previous Caesarean section can be achieved in almost 70 per cent of cases. At that, labour induction does not decrease this indicator and remains within population boundaries.

  17. Development of a procedure for qualitative and quantitative evaluation of human factors as a part of probabilistic safety assessments of nuclear power plants. Part A

    International Nuclear Information System (INIS)

    Richei, A.

    1998-01-01

    The objective of this project is the development of a procedure for the qualitative and quantitative evaluation of human factors in the probabilistic safety assessment for nuclear power plants. The Human Error Rate Assessment and Optimizing System (HEROS) is introduced. The evaluation of a task with HEROS is realized in the three evaluation levels, i.e. 'Management Structure', 'Working Environment' and 'Man-Machine-Interface'. The developed expert system uses the fuzzy set theory for an assessment. For the evaluation of cognitive tasks evaluation criteria are derived also. The validation of the procedure is based on three examples, reflecting the common practice of probabilistic safety assessments and including problems, which cannot, respectively - only insufficiently - be evaluated with the established human risk analysis procedures. HERO applications give plausible and comprehensible results. (orig.) [de

  18. New Strategies for Cultivation and Detection of Previously Uncultured Microbes

    Science.gov (United States)

    Stevenson, Bradley S.; Eichorst, Stephanie A.; Wertz, John T.; Schmidt, Thomas M.; Breznak, John A.

    2004-01-01

    An integrative approach was used to obtain pure cultures of previously uncultivated members of the divisions Acidobacteria and Verrucomicrobia from agricultural soil and from the guts of wood-feeding termites. Some elements of the cultivation procedure included the following: the use of agar media with little or no added nutrients; relatively long periods of incubation (more than 30 days); protection of cells from exogenous peroxides; and inclusion of humic acids or a humic acid analogue (anthraquinone disulfonate) and quorum-signaling compounds (acyl homoserine lactones) in growth media. The bacteria were incubated in the presence of air and in hypoxic (1 to 2% O2 [vol/vol]) and anoxic atmospheres. Some bacteria were incubated with elevated concentrations of CO2 (5% [vol/vol]). Significantly more Acidobacteria were found on isolation plates that had been incubated with 5% CO2. A simple, high-throughput, PCR-based surveillance method (plate wash PCR) was developed. This method greatly facilitated detection and ultimate isolation of target bacteria from as many as 1,000 colonies of nontarget microbes growing on the same agar plates. Results illustrate the power of integrating culture methods with molecular techniques to isolate bacteria from phylogenetic groups underrepresented in culture. PMID:15294811

  19. Development of an Estimating Procedure for the Annual PLAN Process - with Special Emphasis on the Estimating Group

    International Nuclear Information System (INIS)

    Lichtenberg, Steen

    2003-01-01

    This research study deals with the PLAN 2000 procedure. This complex annual estimating procedure is based on the Swedish law on financing, 1992:1537. It requires the Swedish Nuclear Power inspectorate, SKI, to submit to the Government a fully supported annual proposal for the following year's unit fee for nuclear generated electricity to be paid by the owners of the Swedish nuclear power plants. The function of this Fund, KAF, is to finance the future Swedish decommissioning programme. The underlying reason for the study is current criticism of the existing procedure, not least of the composition and working conditions of the analysis group. The purpose of the study is to improve the procedure. The aim is (1) to maximise the realism and neutrality of the necessary estimates in order to allow the KAF Fund to grow steadily at the current rate to the desired target size, allowing it to pay all relevant costs associated with this large decommissioning programme; (2) to do this with a controlled degree of safety; (3) to improve the transparency of the whole procedure in order to avoid any distrust of the procedure and its results. The scope covers all technical and statistical issues; and to some degree also the directly related organisational aspects, notably in respect of the present law and its administration. However, some details are dealt with which seem contrary to the aim of the law. Since 1996, SKI has delegated to the Swedish Nuclear Fuel and Waste Management Co., SKB, the task of performing the basic part of the necessary annual estimating procedure. SKI has then evaluated and supplemented the base estimate before the drafting of the final proposals for the Government and the Board of the Fund, KAFS. Some basic requirements are crucial to the quality of the result of the study: (1) full identification of all potential sources of major uncertainty and the subsequent correct handling of these, (2) balanced and unbiased quantitative evaluation of uncertain

  20. Predicting the Risk to Develop Preeclampsia in the First Trimester Combining Promoter Variant -98A/C of LGALS13 (Placental Protein 13), Black Ethnicity, Previous Preeclampsia, Obesity, and Maternal Age.

    Science.gov (United States)

    Madar-Shapiro, Liora; Karady, Ido; Trahtenherts, Alla; Syngelaki, Argryo; Akolekar, Ranjit; Poon, Liona; Cohen, Ruth; Sharabi-Nov, Adi; Huppertz, Berthold; Sammar, Marei; Juhasz, Kata; Than, Nandor Gabor; Papp, Zoltan; Romero, Roberto; Nicolaides, Kypros H; Meiri, Hamutal

    2017-07-21

    LGALS13 (placental protein 13 [PP13]) promoter DNA polymorphisms was evaluated in predicting preeclampsia (PE), given PP13's effects on hypotension, angiogenesis, and immune tolerance. First-trimester plasma samples (49 term and 18 intermediate) of PE cases matched with 196 controls were collected from King's College Hospital, London, repository. Cell-free DNA was extracted and the LGALS13 exons were sequenced after PCR amplification. Expression of LGALS13 promoter reporter constructs was determined in BeWo trophoblast-like cells with luciferase assays. Adjusted odds ratio (OR) was calculated for the A/A genotype combined with maternal risk factors. The A/A, A/C, and C/C genotypes in the -98 promoter position were in Hardy-Weinberg equilibrium in the control but not in the PE group (p 35, black ethnicity, and maternal age >40 were 15.6 and 11.0, respectively (p promoter variant had lower expression than the "-98C" variant in non-differentiated (-13%, p = 0.04) and differentiated (-26%, p promoter region position (compared to "C") and high OR calculated for the A/A genotype in the -98A/C promoter region position, history of previous PE, BMI >35, advanced maternal age >40, and black ethnicity could serve to aid in PE prediction in the first trimester. © 2017 S. Karger AG, Basel.

  1. Development and validation of a screening procedure to identify speech-language delay in toddlers with cleft palate

    DEFF Research Database (Denmark)

    Jørgensen, Line Dahl; Willadsen, Elisabeth

    2017-01-01

    condition based on assessment of consonant inventory using a real-time listening procedure in combination with parent-reported expressive vocabulary. These measures allowed evaluation of early speech-language skills found to correlate significantly with later speech-language difficulties in longitudinal...... intervention. The results of real-time listening assessment showed good-excellent inter-rater agreement on different consonant inventory measures. Furthermore, there was almost perfect agreement between the children selected for intervention with the screening procedure and the clinical judgment of experienced...

  2. Diagnosis and dosimetry of exposure to sulfur mustard: Development of a standard operating procedure for hemoglobin adducts: Exploratory research on albumin and keratin adducts

    NARCIS (Netherlands)

    Noort, D.; Fidder, A.; Jong, L.P.A. de; Schans, G.P. van der; Benschop, H.P.

    2000-01-01

    A standard operating procedure (SOP) for determination of the sulfur mustard adduct to the N-terminal valine in hemoglobin was developed. By using this SOP, it was found that the Nterminal valine adduct in globin of hairless guinea pigs and marmosets which had been exposed to sulfur mustard (0.5

  3. Diagnosis and dosimetry of exposure to sulfur mustard: Development of a standard operating procedure for mass spectrometric analysis of haemoglobin adducts - Exploratory research on albumin and keratin adducts

    NARCIS (Netherlands)

    Noort, D.; Fidder, A.; Hulst, A.G.; Jong, L.P.A. de; Benschop, H.P.

    2000-01-01

    Experiments were carried out to develop a standard operating procedure for analysis of sulfur mustard adducts to the N-terminal valine in haemoglobin and to explore adduct formation with albumin and keratin. In the first approach, gas chromatography-negative chemical ionization/mass spectrometry

  4. A Guide for Developing Standard Operating Job Procedures for the Activated Sludge - Aeration & Sedimentation Process Wastewater Treatment Facility. SOJP No. 5.

    Science.gov (United States)

    Mason, George J.

    This guide for developing standard operating job procedures for wastewater treatment facilities is devoted to the activated sludge aeration and sedimentation process. This process is for conversion of nonsettleable and nonfloatable materials in wastewater to settleable, floculated biological groups and separation of the settleable solids from the…

  5. Assisted Medical Procedures (AMP)

    Data.gov (United States)

    National Aeronautics and Space Administration — DOCUMENTATION, DEVELOPMENT, AND PROGRESS The AMP was initially being developed as part the Advanced Integrated Clinical System (AICS)-Guided Medical Procedure System...

  6. Preoperative electrocardiography: its cost-effectiveness in detecting abnormalities when a previous tracing exists.

    Science.gov (United States)

    Rabkin, S W; Horne, J M

    1979-01-01

    In 812 patients who underwent routine preoperative electrocardiography a mean of 24.6 months after undergoing electrocardiography at the same institution, the frequency of new abnormalities was estimated to evaluate the cost-effectiveness of this procedure prior to an operation. New abnormalities were judged to be either relevant or irrelevant to the assessment of operative risk, depending upon their previously demonstrated correlation with operative and postoperative morbidity and mortality. Since new abnormalities, especially new relevant abnormalities, were found to be relatively infrequent, the cost-effectiveness of routine preoperative electrocardiography was considered to be low. The evidence suggested that when a previous tracing exists preoperative electrocardiography is most clearly indicated for patients who are 60 years of age or older or whose previous tracing exhibited abnormalities. However, further research is required to develop more sensitive and specific protocols, and to evaluate the role of repeat electrocardiography in clinical decision-making. PMID:111793

  7. Development of a modular lightweight tumour endoprosthesis with novel textile attachment points for the refixation of previously detached muscle groups: Poster presented at 18th EFORT Congress, Sports Activities & Orthopaedic Practice 31 May to 02 June 2017, Vienna

    OpenAIRE

    Grunert, Ronny; Schmidt, Michael; Kopper, Michael; Töppel, Thomas; Rädel, Thomas; Hanus, Sybille; Prietzel, Torsten

    2017-01-01

    Motivation: In tumor endoprosthetics, implants are applied to reconstruct the proximal femur. The main problems of these implants are often the high weight and the biomechanically not optimal attachment of soft tissue. The aim of this work is to solve these problems in order to develop a long-term stable biomechanically correct implant of a proximal femoral replacement. Methods Based on lightweight construction concepts from vehicle construction, a topology optimization was performed with an ...

  8. Developing School Policies and Procedures for Physical Restraint and Seclusion in Nebraska Schools. A Technical Assistance Document

    Science.gov (United States)

    Peterson, Reece L.

    2010-01-01

    The purpose of this document is to provide information and guidance for Nebraska School districts in creating new, or revising existing policies and procedures related to the use of physical restraint and seclusion in school settings. The goal is to create policies that are informed by national policy directions, research, good practice and…

  9. Emotional Development across Adulthood: Differential Age-Related Emotional Reactivity and Emotion Regulation in a Negative Mood Induction Procedure

    Science.gov (United States)

    Kliegel, Matthias; Jager, Theodor; Phillips, Louise H.

    2007-01-01

    The present study examines the hypothesis that older adults might differentially react to a negative versus neutral mood induction procedure than younger adults. The rationale for this expectation was derived from Socioemotional Selectivity Theory (SST), which postulates differential salience of emotional information and ability to regulate…

  10. Design, Development and Evaluation of Collaborative Team Training Method in Virtual Worlds for Time-Critical Medical Procedures

    Science.gov (United States)

    Khanal, Prabal

    2014-01-01

    Medical students acquire and enhance their clinical skills using various available techniques and resources. As the health care profession has move towards team-based practice, students and trainees need to practice team-based procedures that involve timely management of clinical tasks and adequate communication with other members of the team.…

  11. A Guide for Developing Standard Operating Job Procedures for the Sludge Conditioning & Dewatering Process Wastewater Treatment Facility. SOJP No. 11.

    Science.gov (United States)

    Schwing, Carl M.

    This guide describes standard operating job procedures for the sludge conditioning and dewatering process of wastewater treatment facilities. In this process, sludge is treated with chemicals to make the sludge coagulate and give up its water more easily. The treated sludge is then dewatered using a vacuum filter. The guide gives step-by-step…

  12. A Guide for Developing Standard Operating Job Procedures for the Primary Sedimentation Process Wastewater Treatment Facility. SOJP No. 4.

    Science.gov (United States)

    Charles County Community Coll., La Plata, MD.

    This guide describes standard operating job procedures for the primary sedimentation process of wastewater treatment plants. The primary sedimentation process involves removing settleable and suspended solids, in part, from wastewater by gravitational forces, and scum and other floatable solids from wastewater by mechanical means. Step-by-step…

  13. A Guide for Developing Standard Operating Job Procedures for the Screening & Grinding Process Wastewater Treatment Facility. SOJP No. 1.

    Science.gov (United States)

    Deal, Gerald A.; Montgomery, James A.

    This guide describes standard operating job procedures for the screening and grinding process of wastewater treatment facilities. The objective of this process is the removal of coarse materials from the raw waste stream for the protection of subsequent equipment and processes. The guide gives step-by-step instructions for safety inspection,…

  14. A Guide for Developing Standard Operating Job Procedures for the Sludge Thickening Process Wastewater Treatment Facility. SOJP No. 9.

    Science.gov (United States)

    Schwing, Carl M.

    This guide describes standard operating job procedures for the screening and grinding process of wastewater treatment facilities. The objective of this process is the removal of coarse materials from the raw waste stream for the protection of subsequent equipment and processes. The guide gives step-by-step instructions for safety inspection,…

  15. A Guide for Developing Standard Operating Job Procedures for the Tertiary Multimedia Filtration Process Wastewater Treatment Facility. SOJP No. 7.

    Science.gov (United States)

    Petrasek, Al, Jr.

    This guide describes the standard operating job procedures for the tertiary multimedia filtration process of wastewater treatment plants. The major objective of the filtration process is the removal of suspended solids from the reclaimed wastewater. The guide gives step-by-step instructions for pre-start up, start-up, continuous operation, and…

  16. A Guide for Developing Standard Operating Job Procedures for the Digestion Process Wastewater Treatment Facility. SOJP No. 10.

    Science.gov (United States)

    Schwing, Carl M.

    This guide describes standard operating job procedures for the digestion process of wastewater treatment facilities. This process is for reducing the volume of sludge to be treated in subsequent units and to reduce the volatile content of sludge. The guide gives step-by-step instructions for pre-startup, startup, continuous operating, shutdown,…

  17. Procedure generation and verification

    International Nuclear Information System (INIS)

    Sheely, W.F.

    1986-01-01

    The Department of Energy has used Artificial Intelligence of ''AI'' concepts to develop two powerful new computer-based techniques to enhance safety in nuclear applications. The Procedure Generation System, and the Procedure Verification System, can be adapted to other commercial applications, such as a manufacturing plant. The Procedure Generation System can create a procedure to deal with the off-normal condition. The operator can then take correct actions on the system in minimal time. The Verification System evaluates the logic of the Procedure Generator's conclusions. This evaluation uses logic techniques totally independent of the Procedure Generator. The rapid, accurate generation and verification of corrective procedures can greatly reduce the human error, possible in a complex (stressful/high stress) situation

  18. Is a Previously or Currently Reduced Testosterone Level in Male Patients with Type 2 Diabetes Mellitus a Risk Factor for the Development of Coronary Artery Disease? A Systematic Review and Meta-analysis.

    Science.gov (United States)

    Huang, Feng

    2018-04-04

    We aimed to systematically investigate the association between testosterone level and cardiovascular risk in male patients with type 2 diabetes mellitus (T2DM) by comparing male T2DM patients with low testosterone levels to male T2DM patients with normal testosterone levels at baseline in terms of the number of cases of coronary artery disease (CAD). Online databases were carefully searched for studies relating to testosterone, diabetes mellitus, and cardiovascular risk by using the search terms 'testosterone,' 'diabetes mellitus,' and 'coronary artery/cardiovascular disease.' The only endpoint in this analysis was CAD/atherosclerosis/coronary plaque/major adverse coronary event prior to or following testosterone reduction at baseline. The analytical parameters used in this analysis were the risk ratio (RR) with the 95% confidence interval (CI), as obtained using the RevMan 5.3 software. 3467 male patients with T2DM (1079 patients with a low testosterone level versus 2388 patients with a normal testosterone level) were included. The results of this analysis showed that when a random effects model was used, a higher risk of CAD/cardiovascular disease was observed in diabetic patients with a low testosterone level than in those with a normal testosterone level (RR 1.24, 95% CI 0.94-1.63; P = 0.13). However, the difference in risk was not statistically significant. Similarly, with a fixed effects model, a low testosterone level was associated with a higher CAD/cardiovascular risk of disease (RR 1.12, 95% CI 0.98-1.34; P = 0.08); in this case, the difference in risk between the T2DM patients with low and normal testosterone levels approached statistical significance. A previously or currently reduced testosterone level was not found to be statistically significantly associated with a high risk of CAD/cardiovascular disease in male patients with T2DM. However, the difference in risk between the T2DM patients with low and normal testosterone levels was observed

  19. Development of hazard analysis by critical control points (HACCP) procedures to control organic chemical hazards in the agricultural production of raw food commodities.

    Science.gov (United States)

    Ropkins, Karl; Ferguson, Andrew; Beck, Angus J

    2003-01-01

    Hazard Analysis by Critical Control Points (HACCP) is a systematic approach to the identification, assessment, and control of hazards in the food chain. Effective HACCP requires the consideration of all chemical microbiological, and physical hazards. However, current procedures focus primarily on microbiological and physical hazards, while chemical aspects of HACCP have received relatively little attention. In this article we discuss the application of HACCP to organic chemical contaminants and the problems that are likely to be encountered in agriculture. We also present generic templates for the development of organic chemical contaminant HACCP procedures for selected raw food commodities, that is, cereal crops,raw meats, and milk.

  20. Percutaneous endoscopic gastrostomy following previous abdominal surgery.

    Science.gov (United States)

    Stellato, T A; Gauderer, M W; Ponsky, J L

    1984-01-01

    During a 36-month period, 89 patients have undergone percutaneous endoscopic gastrostomy without mortality. Of these patients, 25 (13 infants and children, 12 adults) had prior abdominal procedures that increased their risk for the endoscopic procedure. With two exceptions, all gastrostomies were performed utilizing local anesthesia. There was one major complication, a gastrocolic fistula, which was successfully managed by repeating the endoscopic gastrostomy procedure at a location more cephalad in the stomach. Twenty-two of the gastrostomies were placed for feeding purposes and all of these patients were able to leave the hospital with alimentation accomplished via the tube. Three of the endoscopically placed gastrostomies were for gastrointestinal tract decompression. A total of 255 patient months have been accumulated in these patients with the endoscopically placed gastrostomy in situ. The technique can be safely performed in patients with prior abdominal surgery and in the majority of cases is the technique of choice for establishing a tube gastrostomy. PMID:6428334

  1. Procedural justice, legitimacy beliefs, and moral disengagement in emerging adulthood: Explaining continuity and desistance in the moral model of criminal lifestyle development.

    Science.gov (United States)

    Walters, Glenn D

    2018-02-01

    Research has shown that procedural justice reliably predicts future offending behavior, although there is some indication that this may be more a function of legitimacy beliefs than of procedural justice per se. The current study sought to explain continuity and desistance in the moral model of criminal lifestyle development by comparing legitimacy beliefs, procedural justice, and moral disengagement as initiators and mediators of pathways leading to early adult offending. It was hypothesized that low legitimacy beliefs but not perceived procedural (in)justice or moral disengagement would initiate, and that moral disengagement but not low legitimacy beliefs or procedural injustice would mediate, the effect of low legitimacy beliefs on subsequent offending behavior. This hypothesis was tested in a group of 1,142 young adult males (age range = 18 to 20) from the Pathways to Desistance study (Mulvey, 2012). Results showed that as predicted, the target pathway (legitimacy → moral disengagement → offending) but none of the control pathways achieved a significant indirect effect. Hence, 1 way legitimacy beliefs reduce future offending and lead to desistance is by inhibiting moral disengagement. Besides the theoretical implications of these results, there is also the suggestion that legitimacy beliefs and moral disengagement should be considered for inclusion in secondary prevention and criminal justice intervention programs. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  2. Developing the Implicit Relational Assessment Procedure (IRAP) as a Measure of Bias Towards Pupils with Attention Deficit Hyperactivity Disorder (ADHD)

    OpenAIRE

    Gallagher, Roisin

    2017-01-01

    Negative attitudes toward Attention Deficit Hyperactivity Disorder (ADHD) can lead to delays in help-seeking, negative self-image, social isolation, social rejection, and treatment barriers. The aim of the current research was to extend the research literature on ADHD by using a measure of implicit cognition to complement existing questionnaire/self-report data. Study 1 used a behavioural implicit measure known as the Implicit Relational Assessment Procedure (IRAP) and three explicit measures...

  3. Development and Assessment of a Novel Task Trainer and Targeting Tasks for Ultrasound-guided Invasive Procedures.

    Science.gov (United States)

    Nitsche, Joshua F; Shumard, Kristina M; Brost, Brian C

    2017-06-01

    The American Institute of Ultrasound in Medicine (AIUM) recommends that all providers performing ultrasound-guided invasive procedures be competent in a core set of guidance skills common to all ultrasound-guided procedures, including in-plane and out-of-plane needle guidance and needle imaging optimization techniques such as probe translation, rotation, and heel-toe standoff. To allow for the practice and assessment of these core skills, we have created a novel task trainer and set of targeting tasks, and sought to obtain validity evidence in the content and response process domains for this training and assessment system according to the Standards for Educational and Psychological Testing. We have constructed an ultrasound-guided invasive procedure training system and five targeting tasks that focused on the needle guidance skills outlined by the AIUM. All tasks were performed by obstetrics and gynecology or maternal-fetal medicine physicians with and without experience in ultrasound-guided invasive procedures during a series of simulation workshops. All participants completed a survey regarding the trainer's and the tasks' usefulness in the training of inexperienced physicians. The physicians who completed the tasks had favorable views of task trainer and curriculum. The targeting curriculum was felt to allow practice of all of the core guidance skills outlined by the AIUM. The average response provided for all of the tasks was 4.0 or greater, with half of the items having an average response of 4.5 or higher. We have constructed a task trainer that incorporates all of the core skills outlined by the AIUM. All five tasks received very favorable reviews from both experienced and inexperienced providers. Taken together, our findings suggest they have strong content and response process validity evidence. Copyright © 2017 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

  4. The development of spelling procedures in French-speaking, normal and reading-disabled children: effects of frequency and lexicality.

    OpenAIRE

    Alegria Iscoa, Jesus; Mousty, Philippe

    1996-01-01

    The spelling procedures of normal and reading-disabled French-speaking children matched for reading level were examined. Subjects had to spell frequent and infrequent words containing either inconsistent nondominant graphonemes (e.g. /s/ spelled "c" as in "cigarette," the dominant spelling for /s/ being "s") or consistent context-dependent graphonemes (e.g. /g/ followed by "i"-->"gu") as well as pseudo-words including inconsistent graphonemes presented in different phonological contexts (e.g....

  5. Preoperative screening: value of previous tests.

    Science.gov (United States)

    Macpherson, D S; Snow, R; Lofgren, R P

    1990-12-15

    To determine the frequency of tests done in the year before elective surgery that might substitute for preoperative screening tests and to determine the frequency of test results that change from a normal value to a value likely to alter perioperative management. Retrospective cohort analysis of computerized laboratory data (complete blood count, sodium, potassium, and creatinine levels, prothrombin time, and partial thromboplastin time). Urban tertiary care Veterans Affairs Hospital. Consecutive sample of 1109 patients who had elective surgery in 1988. At admission, 7549 preoperative tests were done, 47% of which duplicated tests performed in the previous year. Of 3096 previous results that were normal as defined by hospital reference range and done closest to the time of but before admission (median interval, 2 months), 13 (0.4%; 95% CI, 0.2% to 0.7%), repeat values were outside a range considered acceptable for surgery. Most of the abnormalities were predictable from the patient's history, and most were not noted in the medical record. Of 461 previous tests that were abnormal, 78 (17%; CI, 13% to 20%) repeat values at admission were outside a range considered acceptable for surgery (P less than 0.001, frequency of clinically important abnormalities of patients with normal previous results with those with abnormal previous results). Physicians evaluating patients preoperatively could safely substitute the previous test results analyzed in this study for preoperative screening tests if the previous tests are normal and no obvious indication for retesting is present.

  6. Automatic electromagnetic valve for previous vacuum

    International Nuclear Information System (INIS)

    Granados, C. E.; Martin, F.

    1959-01-01

    A valve which permits the maintenance of an installation vacuum when electric current fails is described. It also lets the air in the previous vacuum bomb to prevent the oil ascending in the vacuum tubes. (Author)

  7. Photodigitizing procedures

    Science.gov (United States)

    Kilgore, P. D.; Gottbrath, J. H.

    1984-02-01

    This report documents procedures and programs for efficiently running the Photo Digitizing System at the Naval Biodynamics Laboratory. Procedures have been tested and have been found to be effective. Any future acquisitions of programs or changes to current programs should be incorporated in these procedures. On-going research programs use high speed instrumentation cameras to record the motion of test subjects during biodynamic experiments. The films are digitized and the 3-dimensional motion is reconstructed and analyzed. Experimental research is performed to determine the effects of aircraft crashes, ship motion, vibration, aircraft ejection and parachute opening forces on the health and performance of Navy personnel.

  8. Decision-making Procedures

    DEFF Research Database (Denmark)

    Aldashev, Gani; Kirchsteiger, Georg; Sebald, Alexander Christopher

    2009-01-01

    It is a persistent finding in psychology and experimental economics that people's behavior is not only shaped by outcomes but also by decision-making procedures. In this paper we develop a general framework capable of modelling these procedural concerns. Within the context of psychological games we...... define procedures as mechanisms that influence the probabilities of reaching different endnodes. We show that for such procedural games a sequential psychological equilibrium always exists. Applying this approach within a principal-agent context we show that the way less attractive jobs are allocated...

  9. Procedures for the quantification of whole-tissue immunofluorescence images obtained at single-cell resolution during murine tubular organ development.

    Directory of Open Access Journals (Sweden)

    Tsuyoshi Hirashima

    Full Text Available Whole-tissue quantification at single-cell resolution has become an inevitable approach for further quantitative understanding of morphogenesis in organ development. The feasibility of the approach has been dramatically increased by recent technological improvements in optical tissue clearing and microscopy. However, the series of procedures required for this approach to lead to successful whole-tissue quantification is far from developed. To provide the appropriate procedure, we here show tips for each critical step of the entire process, including fixation for immunofluorescence, optical clearing, and digital image processing, using developing murine internal organs such as epididymis, kidney, and lung as an example. Through comparison of fixative solutions and of clearing methods, we found optimal conditions to achieve clearer deep-tissue imaging of specific immunolabeled targets and explain what methods result in vivid volume imaging. In addition, we demonstrated that three-dimensional digital image processing after optical clearing produces objective quantitative data for the whole-tissue analysis, focusing on the spatial distribution of mitotic cells in the epididymal tubule. The procedure for the whole-tissue quantification shown in this article should contribute to systematic measurements of cellular processes in developing organs, accelerating the further understanding of morphogenesis at the single cell level.

  10. Oculoplastic procedures

    Science.gov (United States)

    ... procedures may be done on the: Eyelids Eye sockets Eyebrows Cheeks Tear ducts Face or forehead These ... eyes. These lenses help protect your eyes and shield them from the bright lights of the surgical ...

  11. Concomitant and previous osteoporotic vertebral fractures.

    Science.gov (United States)

    Lenski, Markus; Büser, Natalie; Scherer, Michael

    2017-04-01

    Background and purpose - Patients with osteoporosis who present with an acute onset of back pain often have multiple fractures on plain radiographs. Differentiation of an acute osteoporotic vertebral fracture (AOVF) from previous fractures is difficult. The aim of this study was to investigate the incidence of concomitant AOVFs and previous OVFs in patients with symptomatic AOVFs, and to identify risk factors for concomitant AOVFs. Patients and methods - This was a prospective epidemiological study based on the Registry of Pathological Osteoporotic Vertebral Fractures (REPAPORA) with 1,005 patients and 2,874 osteoporotic vertebral fractures, which has been running since February 1, 2006. Concomitant fractures are defined as at least 2 acute short-tau inversion recovery (STIR-) positive vertebral fractures that happen concomitantly. A previous fracture is a STIR-negative fracture at the time of initial diagnostics. Logistic regression was used to examine the influence of various variables on the incidence of concomitant fractures. Results - More than 99% of osteoporotic vertebral fractures occurred in the thoracic and lumbar spine. The incidence of concomitant fractures at the time of first patient contact was 26% and that of previous fractures was 60%. The odds ratio (OR) for concomitant fractures decreased with a higher number of previous fractures (OR =0.86; p = 0.03) and higher dual-energy X-ray absorptiometry T-score (OR =0.72; p = 0.003). Interpretation - Concomitant and previous osteoporotic vertebral fractures are common. Risk factors for concomitant fractures are a low T-score and a low number of previous vertebral fractures in cases of osteoporotic vertebral fracture. An MRI scan of the the complete thoracic and lumbar spine with STIR sequence reduces the risk of under-diagnosis and under-treatment.

  12. Procedure for Market Analysis in the Research, Development and Innovation Management Unit (R+D+I of the University of Mindelo

    Directory of Open Access Journals (Sweden)

    Joao Dias−da Silva

    2016-12-01

    Full Text Available Research, development and innovation (R + D + i is a competitive factor in organizations and refers to a set of specificities that determine the need for efficient and efficient management. The objective of this scientific paper was to show the application of a procedure for the market analysis of the R & D & I management unit of the University of Mindelo, Republic of Cape Verde. The results achieved by the application of the procedure allowed to perfect the decision-making process in response to the needs of the clients represented by the companies ENAPOR, ELECTRA, among others. In the same way strengthen projects related to the development of software to support business management and its financing from external sources, as well as the competitiveness of the organization.

  13. Development and evaluation of Standard Operating Procedures (SOPs) for quality control tests and radiological protection activities in a Nuclear Medicine Service

    International Nuclear Information System (INIS)

    Krempser, Alexandre R.; Soares, Alexandre B.; Corbo, Rossana

    2011-01-01

    The quality management in Nuclear Medicine Services is a requirement of national and international standards. The Brazilian regulatory agency in health surveillance, the Agencia Nacional de Vigilancia Sanitaria (ANVISA), in its Resolucao de Diretoria Colegiada (Collegiate Directory Resolution) no. 38, requires the elaboration of documents describing the technical and clinical routine activities. This study aimed to elaborate, implement and evaluate Standard Operating Procedures (SOPs) for quality control tests and radiological protection activities in the Nuclear Medicine Service of a university hospital. Eighteen SOPs were developed, involving tasks related to dose calibrator, gamma camera, Geiger-Muller detectors and radiological protection activities. The performance of its application was evaluated for a period of six months. It was observed a reduction in 75% of reported operational errors and 42% of the number of reported incidents with contamination by radioactive material. The SOPs were adequate and successful in its application. New procedures involving clinical activities will also be developed and evaluated. (author)

  14. SU-G-BRB-07: Developing a QA Procedure for Gated VMAT SABR Treatments Using 10 MV Beam in Flattening-Filter Free Mode

    Energy Technology Data Exchange (ETDEWEB)

    Chitsazzadeh, S [University of Victoria, Victoria, British Columbia (Canada); Wells, D [British Columbia Cancer Agency, Victoria, British Columbia (Canada); Mestrovic, A [British Columbia Cancer Agency, Vancouver, British Columbia (Canada)

    2016-06-15

    Purpose: To develop a QA procedure for gated VMAT stereotactic ablative radiotherapy (SABR) treatments. Methods: An interface was constructed to attach the translational stage of a Quasar respiratory motion phantom to a pinpoint ion chamber insert and move the ion chamber inside an ArcCheck diode array. The Quasar phantom controller used a patient specific breathing pattern to translate the ion chamber in a superior-inferior direction inside the ArcCheck. An amplitude-based RPM tracking system was specified to turn the beam on during the exhale phase of the breathing pattern. SABR plans were developed using Eclipse for liver PTVs ranging in size from 3-12 cm in diameter using a 2-arc VMAT technique. Dose was measured in the middle of the penumbra region, where the high dose gradient allowed for sensitive detection of any inaccuracies in gated dose delivery. The overall fidelity of the dose distribution was confirmed using ArcCheck. The sensitivity of the gating QA procedure was investigated with respect to the following four parameters: PTV size, duration of exhale, baseline drift, and gating window size. Results: The difference between the measured dose to a point in the penumbra and the Eclipse calculated dose was under 2% for small residual motions. The QA procedure was independent of PTV size and duration of exhale. Baseline drift and gating window size, however, significantly affected the penumbral dose measurement, with differences of up to 30% compared to Eclipse. Conclusion: This study described a highly sensitive QA procedure for gated VMAT SABR treatments. The QA outcome was dependent on the gating window size and baseline drift. Analysis of additional patient breathing patterns will be required to determine a clinically relevant gating window size and an appropriate tolerance level for this procedure.

  15. Development of an electrothermal atomization laser-excited atomic fluorescence spectrometry procedure for direct measurements of arsenic in diluted serum.

    Science.gov (United States)

    Swart, D J; Simeonsson, J B

    1999-11-01

    A procedure for the direct determination of arsenic in diluted serum by electrothermal atomization laser-excited atomic fluorescence spectrometry (ETA-LEAFS) is reported. Laser radiation needed to excite As at 193.696 and 197.197 nm is generated as the second anti-Stokes stimulated Raman scattering output of a frequency-doubled dye laser operating near 230.5 and 235.5 nm, respectively. Two different LEAFS schemes have been utilized and provide limits of detection of 200-300 fg for As in aqueous standards. When measurements of serum samples diluted 1:10 with deionized water are performed, a stable background signal is observed that can be accounted for by taking measurements with the laser tuned off-wavelength. No As is detected in any of the bovine or human serum samples analyzed. Measurements of 100 pg/mL standard additions of As to a diluted bovine serum sample utilizing either inorganic or organic As species demonstrate a linear relationship of the fluorescence signal to As spike concentration, but exhibit a sensitivity of approximately half that observed in pure aqueous standards. The limit of detection for As in 1:10 diluted serum samples is 65 pg/mL or 650 fg absolute mass, which corresponds to 0.65 ng/mL As in undiluted serum. To our knowledge, the ETA-LEAFS procedure is currently the only one capable of directly measuring As in diluted serum at these levels.

  16. SUPPORT OF ADOPTION OF ADMINISTRATIVE DECISIONS WHEN CARRYING OUT PROCEDURE OF THE CHOICE OF THE PLACE OF PASSING OF PROFESSIONAL DEVELOPMENT OF THE PERSONNEL

    Directory of Open Access Journals (Sweden)

    Yaroslav E. Prokushev

    2015-01-01

    Full Text Available The article is devoted to a problem ofsupport of decision-making for a choiceof the program of passing of professionaldevelopment of the personal. The scope of the work is the sphere of theoreticaland applied questions of human resourcemanagement. The procedure of a choice of the program of professional development of the personal taking into accountthe available needs for its training isoffered.

  17. Fiscal year 1980-81 implementation plan in support of technical development and integration of sampling and aggregation procedures. [crop acreage estimation

    Science.gov (United States)

    1981-01-01

    The specific objectives of the FY 1980-81 tasks are: (1) further refinements to the weighted aggregation procedure; (2) improved approaches for estimating within-stratum variance; (3) more intensive investigation of alternative sampling strategies such as full-frame sampling strategy, and (4) further developments in regard to a simulated approach for assessing the performance of the overall designed sampling and aggregation system.

  18. Uterine rupture without previous caesarean delivery

    DEFF Research Database (Denmark)

    Thisted, Dorthe L. A.; H. Mortensen, Laust; Krebs, Lone

    2015-01-01

    OBJECTIVE: To determine incidence and patient characteristics of women with uterine rupture during singleton births at term without a previous caesarean delivery. STUDY DESIGN: Population based cohort study. Women with term singleton birth, no record of previous caesarean delivery and planned...... vaginal delivery (n=611,803) were identified in the Danish Medical Birth Registry (1997-2008). Medical records from women recorded with uterine rupture during labour were reviewed to ascertain events of complete uterine rupture. Relative Risk (RR) and adjusted Relative Risk Ratio (aRR) of complete uterine...... rupture with 95% confidence intervals (95% CI) were ascertained according to characteristics of the women and of the delivery. RESULTS: We identified 20 cases with complete uterine rupture. The incidence of complete uterine rupture among women without previous caesarean delivery was about 3...

  19. Reoperative sentinel lymph node biopsy after previous mastectomy.

    Science.gov (United States)

    Karam, Amer; Stempel, Michelle; Cody, Hiram S; Port, Elisa R

    2008-10-01

    Sentinel lymph node (SLN) biopsy is the standard of care for axillary staging in breast cancer, but many clinical scenarios questioning the validity of SLN biopsy remain. Here we describe our experience with reoperative-SLN (re-SLN) biopsy after previous mastectomy. Review of the SLN database from September 1996 to December 2007 yielded 20 procedures done in the setting of previous mastectomy. SLN biopsy was performed using radioisotope with or without blue dye injection superior to the mastectomy incision, in the skin flap in all patients. In 17 of 20 patients (85%), re-SLN biopsy was performed for local or regional recurrence after mastectomy. Re-SLN biopsy was successful in 13 of 20 patients (65%) after previous mastectomy. Of the 13 patients, 2 had positive re-SLN, and completion axillary dissection was performed, with 1 having additional positive nodes. In the 11 patients with negative re-SLN, 2 patients underwent completion axillary dissection demonstrating additional negative nodes. One patient with a negative re-SLN experienced chest wall recurrence combined with axillary recurrence 11 months after re-SLN biopsy. All others remained free of local or axillary recurrence. Re-SLN biopsy was unsuccessful in 7 of 20 patients (35%). In three of seven patients, axillary dissection was performed, yielding positive nodes in two of the three. The remaining four of seven patients all had previous modified radical mastectomy, so underwent no additional axillary surgery. In this small series, re-SLN was successful after previous mastectomy, and this procedure may play some role when axillary staging is warranted after mastectomy.

  20. Development, optimization, and validation of a novel extraction procedure for the removal of opiates from human hair's surface.

    Science.gov (United States)

    Restolho, José; Barroso, Mário; Saramago, Benilde; Dias, Mário; Afonso, Carlos A M

    2015-05-01

    Room temperature ionic liquids (ILs) have proved to be efficient extraction media for several systems, and their ability to capture volatile compounds from the atmosphere is well established. We report herein a contactless extraction procedure for the removal of opiate drugs from the surface of human hair. The compounds were chosen as a model drug, particularly due to their low volatility. Equal amounts of IL and hair (about 100 mg) were introduced in a customized Y-shaped vial, and the process occurred simply by heating. After testing several ILs, some of them (e.g. 1-methyl-3-ethanol-imidazolium tetrafluoroborate, phenyl-trimethyl-ammonium triflate or bis(dimethyl) diheptylguanidinium iodide) showed extraction efficiencies higher than 80% for the two studied compounds, morphine and 6-monoacetylmorphine. Using the design of experiments (DOE) approach as an optimization tool, and bearing in mind the hygroscopic properties of the ILs (in particular, 1-methyl-3-ethanol-imidazolium tetrafluoroborate), the process was optimized concerning the following variables: temperature (50-120 ºC), extraction time (8-24 h), IL amount (50-200 mg) and water content of the IL (0.01-60%). This study not only provided the optimum conditions for the process (120 ºC, 16 h, 100 mg of IL containing 40% of water), but has also showed that the water content of the IL represents the variable with the most significant effect on the extraction efficiency. Finally, we validated our method through the comparison of the results obtained by treating hair samples with the described procedure to those obtained using a standard washing method and criteria for positivity. Copyright © 2014 John Wiley & Sons, Ltd.

  1. INTRODUCTION Previous reports have documented a high ...

    African Journals Online (AJOL)

    pregnancy if they were married, educated, had dental insurance, previously used dental services when not pregnant, or had knowledge about the possible connection between oral health and pregnancy outcome8. The purpose of this study was to explore the factors determining good oral hygiene among pregnant women ...

  2. Empowerment perceptions of educational managers from previously ...

    African Journals Online (AJOL)

    The perceptions of educational manag ers from previously disadvantaged primary and high schools in the Nelson Mandela Metropole regarding the issue of empowerment are outlined and the perceptions of educational managers in terms of various aspects of empowerment at different levels reflected. A literature study ...

  3. Management of choledocholithiasis after previous gastrectomy.

    Science.gov (United States)

    Anwer, S; Egan, R; Cross, N; Guru Naidu, S; Somasekar, K

    2017-09-01

    Common bile duct stones in patients with a previous gastrectomy can be a technical challenge because of the altered anatomy. This paper presents the successful management of two such patients using non-traditional techniques as conventional endoscopic retrograde cholangiopancreatography was not possible.

  4. Laboratory Grouping Based on Previous Courses.

    Science.gov (United States)

    Doemling, Donald B.; Bowman, Douglas C.

    1981-01-01

    In a five-year study, second-year human physiology students were grouped for laboratory according to previous physiology and laboratory experience. No significant differences in course or board examination performance were found, though correlations were found between predental grade-point averages and grouping. (MSE)

  5. Interdisciplinary Development of an Improved Emergency Department Procedural Work Surface Through Iterative Design and Use Testing in Simulated and Clinical Environments.

    Science.gov (United States)

    Zhang, Xiao C; Bermudez, Ana M; Reddy, Pranav M; Sarpatwari, Ravi R; Chheng, Darin B; Mezoian, Taylor J; Schwartz, Victoria R; Simmons, Quinneil J; Jay, Gregory D; Kobayashi, Leo

    2017-03-01

    A stable and readily accessible work surface for bedside medical procedures represents a valuable tool for acute care providers. In emergency department (ED) settings, the design and implementation of traditional Mayo stands and related surface devices often limit their availability, portability, and usability, which can lead to suboptimal clinical practice conditions that may affect the safe and effective performance of medical procedures and delivery of patient care. We designed and built a novel, open-source, portable, bedside procedural surface through an iterative development process with use testing in simulated and live clinical environments. The procedural surface development project was conducted between October 2014 and June 2016 at an academic referral hospital and its affiliated simulation facility. An interdisciplinary team of emergency physicians, mechanical engineers, medical students, and design students sought to construct a prototype bedside procedural surface out of off-the-shelf hardware during a collaborative university course on health care design. After determination of end-user needs and core design requirements, multiple prototypes were fabricated and iteratively modified, with early variants featuring undermattress stabilizing supports or ratcheting clamp mechanisms. Versions 1 through 4 underwent 2 hands-on usability-testing simulation sessions; version 5 was presented at a design critique held jointly by a panel of clinical and industrial design faculty for expert feedback. Responding to select feedback elements over several surface versions, investigators arrived at a near-final prototype design for fabrication and use testing in a live clinical setting. This experimental procedural surface (version 8) was constructed and then deployed for controlled usability testing against the standard Mayo stands in use at the study site ED. Clinical providers working in the ED who opted to participate in the study were provided with the prototype

  6. Development of manual procedures for care of pregnant patients in radiotherapy service; Desarrollo de manual de procedimentos para atencion de pacientes embarazadas en servicio de radioterapia

    Energy Technology Data Exchange (ETDEWEB)

    Scarabino, M.L., E-mail: maliscarabino@gmail.com [Hospital Italiano de Buenos Aires (HIBA), Buenos Aires (Argentina); Ruggeri, R.M.; Colombo, S.; Mairal, L.; Sardi, M.E., E-mail: ricardoruggeri@gmail.com [Mevaterapia Centro Medico, Buenos Aires (Argentina)

    2013-11-01

    The work involves the creation of a manual of procedures for the care of pregnant patients in a radiotherapy center in which each instance of treatment is included, from the obstetrician-oncology comprehensive assessment during admission to establishing controls newborn and its subsequent development in multidisciplinary team. For the preparation of the manual had to design an anthropomorphic phantom that resembles a pregnant woman, which was used to carry out internal and external dosimetry. In turn imparted calculations fetal doses using TPS, imaging tests with MRI, avoiding the use of the tomograph and adapted to the resonator involved were carried immobilizer. All experiences and progress made during the treated cases are introduced in the procedures manual, making it a dynamic tool for continuous improvement for the institution.

  7. Development of a simple desulfurization procedure for the determination of butyltins in complex sediment samples using gas chromatography-pulsed flame photometric detection.

    Science.gov (United States)

    Bravo, M; Valenzuela, A; Quiroz, W; Pinto, M; Flores, M; Pinochet, H

    2010-05-15

    In this study a rapid solid phase extraction (SPE) procedure was developed to minimize the effect of different sulfur species for the determination of butyltin in sediments. The organosulfur species and organotins were firstly retained on C8 cartridges and then organotins were selectively eluted and analyzed by gas chromatography-pulsed flame photometric detection (GC-PFPD). Optimal conditions for the SPE procedure were obtained using an experimental design approach. The method's accuracy was established by analyzing a certified reference material (CRM), BCR-646 freshwater sediment. The experimental values were found to be in agreement with the assigned values for butyltins. Finally, complex sediment samples collected from a Chilean harbor were analyzed using this methodology to demonstrate its analytical potential for the determination of butyltin in environmental samples.

  8. Previously unknown organomagnesium compounds in astrochemical context

    OpenAIRE

    Ruf, Alexander

    2018-01-01

    We describe the detection of dihydroxymagnesium carboxylates (CHOMg) in astrochemical context. CHOMg was detected in meteorites via ultrahigh-resolving chemical analytics and represents a novel, previously unreported chemical class. Thus, chemical stability was probed via quantum chemical computations, in combination with experimental fragmentation techniques. Results propose the putative formation of green-chemical OH-Grignard-type molecules and triggered fundamental questions within chemica...

  9. Pixel value measurement of microcalcification specks in digitized X-ray film images for image quality assessment. Automatic procedure developed using excel functions

    International Nuclear Information System (INIS)

    Ehara, Norishige; Imamura, Keiko; Inada, Youichi; Nakajima, Yasuo; Fukuda, Mamoru; Higashida, Yoshiharu

    2003-01-01

    We previously reported a method of pixel value averaging for microcalcification specks on digitized mammographic phantom images. These average values are considered to represent the pixel value of a speck for quality control in comparison to its maximal peak value. In this report, we described an automatic processing procedure using a spreadsheet to derive the average and peak values of the pixel value of a speck. A hundred and twenty specks in 10 phantoms were processed using the spread-sheet, and average and peak values were compared. In the examination of the digitized mammography images of RMI 156 phantoms for two calcification speck groups, the average and peak values showed good correlation. Therefore, we concluded the peak values could be used as substitutes for the average values for a quality control purpose. However, as the regression coefficients of the two speck groups were significantly different, the relationship between the average and peak value seemed to depend on speck sizes. (author)

  10. Development of procedures for calculating stiffness and damping properties of elastomers in engineering applications. Part 1: Verification of basic methods

    Science.gov (United States)

    Chiang, T.; Tessarzik, J. M.; Badgley, R. H.

    1972-01-01

    The primary aim of this investigation was verification of basic methods which are to be used in cataloging elastomer dynamic properties (stiffness and damping) in terms of viscoelastic model constants. These constants may then be used to predict dynamic properties for general elastomer shapes and operating conditions, thereby permitting optimum application of elastomers as energy absorption and/or energy storage devices in the control of vibrations in a broad variety of applications. The efforts reported involved: (1) literature search; (2) the design, fabrication and use of a test rig for obtaining elastomer dynamic test data over a wide range of frequencies, amplitudes, and preloads; and (3) the reduction of the test data, by means of a selected three-element elastomer model and specialized curve fitting techniques, to material properties. Material constants thus obtained have been used to calculate stiffness and damping for comparison with measured test data. These comparisons are excellent for a number of test conditions and only fair to poor for others. The results confirm the validity of the basic approach of the overall program and the mechanics of the cataloging procedure, and at the same time suggest areas in which refinements should be made.

  11. Integration of the Response Surface Methodology with the Compromise Decision Support Problem in Developing a General Robust Design Procedure

    Science.gov (United States)

    Chen, Wei; Tsui, Kwok-Leung; Allen, Janet K.; Mistree, Farrokh

    1994-01-01

    In this paper we introduce a comprehensive and rigorous robust design procedure to overcome some limitations of the current approaches. A comprehensive approach is general enough to model the two major types of robust design applications, namely, robust design associated with the minimization of the deviation of performance caused by the deviation of noise factors (uncontrollable parameters), and robust design due to the minimization of the deviation of performance caused by the deviation of control factors (design variables). We achieve mathematical rigor by using, as a foundation, principles from the design of experiments and optimization. Specifically, we integrate the Response Surface Method (RSM) with the compromise Decision Support Problem (DSP). Our approach is especially useful for design problems where there are no closed-form solutions and system performance is computationally expensive to evaluate. The design of a solar powered irrigation system is used as an example. Our focus in this paper is on illustrating our approach rather than on the results per se.

  12. Development of a reliable estimation procedure of radioactivity inventory in a BWR plant due to neutron irradiation for decommissioning

    Science.gov (United States)

    Tanaka, Ken-ichi; Ueno, Jun

    2017-09-01

    Reliable information of radioactivity inventory resulted from the radiological characterization is important in order to plan decommissioning planning and is also crucial in order to promote decommissioning in effectiveness and in safe. The information is referred to by planning of decommissioning strategy and by an application to regulator. Reliable information of radioactivity inventory can be used to optimize the decommissioning processes. In order to perform the radiological characterization reliably, we improved a procedure of an evaluation of neutron-activated materials for a Boiling Water Reactor (BWR). Neutron-activated materials are calculated with calculation codes and their validity should be verified with measurements. The evaluation of neutron-activated materials can be divided into two processes. One is a distribution calculation of neutron-flux. Another is an activation calculation of materials. The distribution calculation of neutron-flux is performed with neutron transport calculation codes with appropriate cross section library to simulate neutron transport phenomena well. Using the distribution of neutron-flux, we perform distribution calculations of radioactivity concentration. We also estimate a time dependent distribution of radioactivity classification and a radioactive-waste classification. The information obtained from the evaluation is utilized by other tasks in the preparatory tasks to make the decommissioning plan and the activity safe and rational.

  13. Development of a dual-isotope procedure for the tagging and identification of manufactured products: application to explosives.

    Science.gov (United States)

    Carames-Pasaron, Isabel; Rodríguez-Castrillón, José Ángel; Moldovan, Mariella; Alonso, J Ignacio García

    2012-01-03

    A novel chemical tagging approach, based on a dual-isotope procedure, is presented. The method has been applied to explosives tagging. The method is based on the addition to the explosive of two enriched isotopes of the same element, which may be already present within it, at a given molar ratio. This dual-isotope approach will give a unique fingerprint to the tagged explosive. Further, the authentication of the tagged explosive or its residues will be obtained by comparison of the ratio of molar fractions experimentally measured by inductively coupled plasma mass spectrometry (ICP-MS) with the molar fraction ratio of the tagging mixture. The novelty of this tagging method relies on working with isotope abundances and molar fraction ratios instead of the classical isotope ratios, and this fact constitutes the strong point of the described approach since the molar ratio is not affected by physical, chemical, or biochemical processes, and it is also not disturbed by environmental contamination with the natural abundance element. Furthermore, the use of molar fraction ratios overcomes the nonhomogeneous distribution of the tagging element within the explosive. As the tagging element can be present at trace or ultratrace levels, a very small amount of enriched isotopes needs to be added, denoting a low cost solution. Also, the use of enriched stable isotopes of nontoxic elements will have negligible health effects or affect the environment. © 2011 American Chemical Society

  14. The U.S. Agency-Level Bid Protest Mechanism: A Model for Bid Challenge Procedures in Developing Nations

    National Research Council Canada - National Science Library

    Troff, Erik A

    2005-01-01

    ... comply with established procurement rules. The decisive question for a developing nation is which of the available structural options best integrates the essential elements of an effective bid protest system in the context of existing legal...

  15. Endoscopic ultrasound-guided fine-needle aspiration in patients with mediastinal abnormalities and previous extrathoracic malignancy

    NARCIS (Netherlands)

    Kramer, H; Koeter, GH; Sleijfer, DT; van Putten, JWG; Groen, HJM

    Enlarged mediastinal lymph nodes inpatients with previous extrathoracic malignancy require pathological verification. However, surgical procedures lead to morbidity and (rarely) mortality. Endoscopic ultrasound with fine-needle aspiration (EUS-FNA) is a minimally invasive, outpatient procedure. We

  16. Development of a voltammetric procedure for assay of the antihistamine drug hydroxyzine at a glassy carbon electrode: Quantification and pharmacokinetic studies.

    Science.gov (United States)

    Beltagi, A M; Abdallah, O M; Ghoneim, M M

    2008-01-15

    An electrochemical study of hydroxyzine at a glassy carbon electrode was carried out in the Britton-Robinson universal buffer of pH 2-11. Hydroxyzine was oxidized in a single two-electron irreversible process controlled mainly by adsorption. A simple, sensitive and time-saving square-wave adsorptive anodic stripping voltammetric procedure has been developed for determination of hydroxyzine in its commercial tablets and human serum without prior extraction. The optimized procedural conditions were: frequency=120Hz, scan increment=10mV, pulse-amplitude=25mV, accumulation potential=-0.3V, accumulation time=90-300s and a Britton-Robinson universal buffer of pH 4 as a supporting electrolyte. Mean recoveries of 100.5+/-0.71 and 98.6+/-1.12% (n=5) were achieved for assay of hydroxyzine in Atarax 10 and 25mg dosage forms, respectively. Limit of detection of 1.5x10(-8)molL(-1) (5.624ngmL(-1)) and limit of quantitation of 5.0x10(-8)molL(-1) (18.746ngmL(-1)) were achieved in human serum with a mean recovery of 98.4+/-1.22%, without prior extraction of the drug. Moreover, the described procedure was applied for evaluating the pharmacokinetic parameters of hydroxyzine in plasma of two healthy volunteers after administration of a single oral dose (Atarax)-25mg).

  17. Radiochemical procedures

    International Nuclear Information System (INIS)

    Lyon, W.S.

    1982-01-01

    The modern counting instrumentation has largely obviated the need for separation processes in the radiochemical analysis but problems in low-level radioactivity measurement, environmental-type analyses, and special situations caused in the last years a renaissance of the need for separation techniques. Most of the radiochemical procedures, based on the classic works of the Manhattan Project chemists of the 1940's, were published in the National Nuclear Energy Series (NNES). Improvements such as new solvent extraction and ion exchange separations have been added to these methods throughout the years. Recently the Los Alamos Group have reissued their collected Radiochemical Procedures containing a short summary and review of basic inorganic chemistry - 'Chemistry of the Elements on the Basis of Electronic Configuration'. (A.L.)

  18. Japanese experiences in human resources development in the nuclear fields and proposal on procedure of the 1st seminar

    International Nuclear Information System (INIS)

    Murao, Yoshio

    2000-01-01

    The Atomic Energy Basic Act was enforced in 1956. The law prescribed establishment of the Atomic Energy Commission (establishment of the Nuclear Safety Commission was added in 1978), definition of administrative bodies for nuclear fuel materials and reactors and radiation protection, and necessary regulatory laws. The law also prescribed establishment of a national nuclear center for R and D and human resources development, i.e. Japan Atomic Energy Research Institute (JAERI) was established in 1956. The Nuclear Technology and Education Center (NuTEC) RI school was opened in 1958. Establishments of Power Reactor and Nuclear Fuel Development Corporation and National Institute of Radiological Science were in 1956 and 1957, respectively. In universities, nuclear facilities were constructed for supplying young human resources based on decision by Ministry of Education after 1961. The foundation of Japan Atomic Energy Power Co. (JAPCO) was in 1957. In the NuTEC, a variety of training courses had been prepared and carried out to meet the requirements of the nuclear community. Many leaders and experts had been produced and they worked for development of nuclear infrastructure in Japan. International training programs were started in 1985 and the experiences were applied for helping Asian countries to develop the manpower for nuclear infrastructure. Japanese safety actions for nuclear technology had strongly depended on that of USA. Therefore, much efforts on safety evaluation and phenomenological understanding are necessary in Japan. Recent tendency is changed from development-minded approach to safety-minded approach and is focused more on efforts to get public consent on nuclear energy. However, Japanese experiences will be useful for developing human resources in other countries. The NuTEC of JAERI will operate the seminar once a year. The seminar will be implemented; to get mutual recognition on present status and problems of regional countries by gathering information

  19. Approache Pluraliste du Developpement et Etude des Variations Procedurals en Production D'Orthographes Inventees. [A Pluralistic Approach to the Development and Study of Procedural Variations in the Production of Invented Spelling.

    Science.gov (United States)

    Gelet, Isabelle Montesinos

    2002-01-01

    This study used a pluralistic model to examine the procedures used by two preschoolers to achieve written productions using invented orthographies. The model allows children's procedural variations to be taken into consideration by understanding the hierarchy of different processing modes available to children in completing the task and…

  20. Model of Procedure Usage – Results from a Qualitative Study to Inform Design of Computer-Based Procedures

    Energy Technology Data Exchange (ETDEWEB)

    Johanna H Oxstrand; Katya L Le Blanc

    2012-07-01

    The nuclear industry is constantly trying to find ways to decrease the human error rate, especially the human errors associated with procedure use. As a step toward the goal of improving procedure use performance, researchers, together with the nuclear industry, have been looking at replacing the current paper-based procedures with computer-based procedure systems. The concept of computer-based procedures is not new by any means; however most research has focused on procedures used in the main control room. Procedures reviewed in these efforts are mainly emergency operating procedures and normal operating procedures. Based on lessons learned for these previous efforts we are now exploring a more unknown application for computer based procedures - field procedures, i.e. procedures used by nuclear equipment operators and maintenance technicians. The Idaho National Laboratory, the Institute for Energy Technology, and participants from the U.S. commercial nuclear industry are collaborating in an applied research effort with the objective of developing requirements and specifications for a computer-based procedure system to be used by field operators. The goal is to identify the types of human errors that can be mitigated by using computer-based procedures and how to best design the computer-based procedures to do this. The underlying philosophy in the research effort is “Stop – Start – Continue”, i.e. what features from the use of paper-based procedures should we not incorporate (Stop), what should we keep (Continue), and what new features or work processes should be added (Start). One step in identifying the Stop – Start – Continue was to conduct a baseline study where affordances related to the current usage of paper-based procedures were identified. The purpose of the study was to develop a model of paper based procedure use which will help to identify desirable features for computer based procedure prototypes. Affordances such as note taking, markups

  1. 22 CFR 1508.610 - What procedures does the African Development Foundation use in suspension and debarment actions?

    Science.gov (United States)

    2010-04-01

    ... informally as practicable, consistent with principles of fundamental fairness. (a) For suspension actions, we... Foundation use in suspension and debarment actions? 1508.610 Section 1508.610 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) General Principles Relating to...

  2. Development of a procedure to model high-resolution wind profiles from smoothed or low-frequency data

    Science.gov (United States)

    Camp, D. W.

    1977-01-01

    The derivation of simulated Jimsphere wind profiles from low-frequency rawinsonde data and a generated set of white noise data are presented. A computer program is developed to model high-resolution wind profiles based on the statistical properties of data from the Kennedy Space Center, Florida. Comparison of the measured Jimsphere data, rawinsonde data, and the simulated profiles shows excellent agreement.

  3. Activities with regard to research and development of technics for SNR 300 reactor vessel in-service inspection procedures

    International Nuclear Information System (INIS)

    Hoeller, K.; Kirchner, G.; Menck, J.

    1980-01-01

    During the development of SNR 300 in-service inspection equipment, several branches were tested by experiment. In this report special steps for testing of manipulation systems and additional engineering equipment for control systems, such as coupling fluid circuit or camera cooling system are considered more in detail

  4. Endoscopic Third Ventriculostomy in Previously Shunted Children

    Directory of Open Access Journals (Sweden)

    Eva Brichtova

    2013-01-01

    Full Text Available Endoscopic third ventriculostomy (ETV is a routine and safe procedure for therapy of obstructive hydrocephalus. The aim of our study is to evaluate ETV success rate in therapy of obstructive hydrocephalus in pediatric patients formerly treated by ventriculoperitoneal (V-P shunt implantation. From 2001 till 2011, ETV was performed in 42 patients with former V-P drainage implantation. In all patients, the obstruction in aqueduct or outflow parts of the fourth ventricle was proved by MRI. During the surgery, V-P shunt was clipped and ETV was performed. In case of favourable clinical state and MRI functional stoma, the V-P shunt has been removed 3 months after ETV. These patients with V-P shunt possible removing were evaluated as successful. In our group of 42 patients we were successful in 29 patients (69%. There were two serious complications (4.7%—one patient died 2.5 years and one patient died 1 year after surgery in consequence of delayed ETV failure. ETV is the method of choice in obstructive hydrocephalus even in patients with former V-P shunt implantation. In case of acute or scheduled V-P shunt surgical revision, MRI is feasible, and if ventricular system obstruction is diagnosed, the hydrocephalus may be solved endoscopically.

  5. Books average previous decade of economic misery.

    Science.gov (United States)

    Bentley, R Alexander; Acerbi, Alberto; Ormerod, Paul; Lampos, Vasileios

    2014-01-01

    For the 20(th) century since the Depression, we find a strong correlation between a 'literary misery index' derived from English language books and a moving average of the previous decade of the annual U.S. economic misery index, which is the sum of inflation and unemployment rates. We find a peak in the goodness of fit at 11 years for the moving average. The fit between the two misery indices holds when using different techniques to measure the literary misery index, and this fit is significantly better than other possible correlations with different emotion indices. To check the robustness of the results, we also analysed books written in German language and obtained very similar correlations with the German economic misery index. The results suggest that millions of books published every year average the authors' shared economic experiences over the past decade.

  6. Soviet-designed pressurized water reactor symptomatic emergency operating instruction analytical procedure: approach, methodology, development and application

    International Nuclear Information System (INIS)

    Beelman, R.J.

    1999-01-01

    A symptom approach to the analytical validation of symptom-based EOPs includes: (1) Identification of critical safety functions to the maintenance of fission product barrier integrity; (2) Identification of the symptoms which manifest an impending challenge to critical safety function maintenance; (3) Development of a symptomatic methodology to delineate bounding plant transient response modes; (4) Specification of bounding scenarios; (5) Development of a systematic calculational approach consistent with the objectives of the methodology; (6) Performance of thermal-hydraulic computer code calculations implementing the analytical methodology; (7) Interpretation of the analytical results on the basis of information available to the operator; (8) Application of the results to the validation of the proposed operator actions; (9) Production of a technical basis document justifying the proposed operator actions. (author)

  7. Development of a Procedure to Increase Awareness and Reporting of Counterintelligence and Terrorism Indicators: Personal Acknowledgment of Staff Security (PASS)

    Science.gov (United States)

    2013-02-27

    unstructured clinical judgment, actuarial , and structured professional judgment. Most of the available assessment instruments were designed to be used in...who was involved and at what point in the research process they were conducted. For instance, personnel at the FBI Behavioral Science Unit were...Low base rates also make it difficult to develop empirically based actuarial prediction instruments for this type of threat assessment (Pressman, 2009

  8. Limit of detection and limit of quantification development procedures for organochlorine pesticides analysis in water and sediment matrices

    Science.gov (United States)

    2013-01-01

    Background Reliable values for method validity of organochlorine pesticides determination were investigated, in water by solid phase extraction and in sediment by Soxhlet extraction, followed by gas chromatography equipped with an electron capture detector. Organochlorine pesticides are categorized as Persistent Organic Pollutants. Hence, critical decisions to control exposure to these chemicals in the environment are based on their levels in different media; it is important to find valid qualitative and quantitative results for these components. In analytical chemistry, internal quality procedures are applied to produce valid logical results. Result In this study, 18 organochlorine pesticides were targeted for analysis and determination in water and river sediment. Experiments based on signal-to-noise ratio, calibration curve slope and laboratory fortified blank methods were conducted to determine the limits of qualification and quantification. The data were compared with each other. The limitation values, following Laboratory Fortified Blank, showed significant differences in the signal-to-noise ratio and calibration curve slope methods, which are assumed in the results for the sample concentration factor to be 1,000 times in water and 10 times in sediment matrices. The method detection limit values were found to be between 0.001 and 0.005 μg/L (mean of 0.002 ± 0.001) and 0.001 and 0.005 μg/g (mean of 0.001 ± 0.001). The quantification limits were found to be between 0.002 and 0.016 μg/L (mean of 0.006 ± 0.004) and 0.003 and 0.017 μg/g (mean of 0.005 ± 0.003 μg/L) for water and sediment, respectively, based on the laboratory fortified blank method. Because of different slopes in the calibration methods, it was also found that the limitation values for some components from the internal standard were higher than from external standard calibration, because in the latter a factor for injection efficiency is applied for calibration

  9. Reforming Russian Civil Procedur

    Directory of Open Access Journals (Sweden)

    Dmitry Maleshin

    2016-01-01

    Full Text Available The II Annual Symposium of the journal Herald of Civil Procedure ‘2015: The Civil Procedure 2.0: Reform and Current State’ took place on October 9, 2015, at the Faculty of Law of Kazan (Volga region Federal University.The Symposium is now an established tradition for the University. In 2015 it brought together in Kazan eminent scholars of civil procedure from cities across the whole of Russia: Moscow, St. Petersburg, Saratov, Ekaterinburg, Omsk, Samara, Nizhnekamsk and others. This large-scale event attracted the attention not only of Russian scholars, but also of legal scholars from abroad: Elisabetta Silvestri (Professor, University of Pavia, Italy, William B. Simons (Professor, University of Tartu, Estonia, Jaroslav Turlukovsky (Professor, Warsaw University, Poland, Stuart H. Schultz (Practising Attorney, USA, Irina Izarova (Associate Professor, Taras Shevchenko National University of Kyiv, Ukraine.The opening ceremony of the Symposium began with greetings to all participants and best wishes for productive discussions. Participants were welcomed with remarks by Marat Khairullin, Deputy Chair of the Supreme Court of the Republic of Tatarstan, Radik Ilyasov, Head of the Federal Bailiff Service of the Republic of Tatarstan, and Ildar Tarkhanov, Academic Supervisor at the Faculty of Law. They expressed their appreciation for the great value of the journal Herald of Civil Procedure in the growth of the science of civil procedure and enforcement procedure, and for its contributions to the development of the judicial system of the Russian Federation.In addition to hearing prepared reports and discussing viewpoints on current issues of civil and arbitration procedure, participants attended presentations by representatives from procedural law periodicals in the frame of the Symposium. The Editor-in-Chief of Herald of Civil Procedure, Damir Valeev, and the Commercial Director of the Statut Publishing House (Moscow, Kirill Samoilov, presented new

  10. Development of a sufficient and effective procedure for transformation of an oleaginous yeast, Rhodosporidium toruloides DMKU3-TK16.

    Science.gov (United States)

    Tsai, Yung-Yu; Ohashi, Takao; Kanazawa, Takenori; Polburee, Pirapan; Misaki, Ryo; Limtong, Savitree; Fujiyama, Kazuhito

    2017-05-01

    Rhodosporidium toruloides DMKU3-TK16 (TK16), a basidiomycetous yeast isolated in Thailand, can produce a large amount of oil corresponding to approximately 70 % of its dry cell weight. However, lack of a sufficient and efficient transformation method makes further genetic manipulation of this organism difficult. We here developed a new transformation system for R. toruloides using a lithium acetate method with the Sh ble gene as a selective marker under the control of the R. toruloides ATCC 10657 GPD1 promoter. A linear DNA fragment containing the Sh ble gene expression cassette was integrated into the genome, and its integration was confirmed by colony PCR and Southern blot. Then, we further optimized the parameters affecting the transformation efficiency, such as the amount of linear DNA, the growth phase, the incubation time in the transformation mixture, the heat shock treatment temperature, the addition of DMSO and carrier DNA, and the recovery incubation time. With the developed method, the transformation efficiency of approximately 25 transformants/μg DNA was achieved. Compared with the initial trial, transformation efficiency was enhanced 417-fold. We further demonstrated the heterologous production of EGFP in TK16 by microscopic observation and immunoblot analysis, and use the technique to disrupt the endogenous URA3 gene. The newly developed method is thus simple and time saving, making it useful for efficient introduction of an exogenous gene into R. toruloides strains. Accordingly, this new practical approach should facilitate the molecular manipulation, such as target gene introduction and deletion, of TK16 and other R. toruloides strains as a major source of biodiesel.

  11. Philosophy, policy and procedures of the World Organisation for Animal Health for the development of standards in animal welfare.

    Science.gov (United States)

    Petrini, A; Wilson, D

    2005-08-01

    Animal welfare was identified as a priority for the World Organisation for Animal Health (OIE) in the 2001-2005 OIE Strategic Plan. Member Countries recognised that, as animal protection is a complex, multi-faceted public policy issue which includes important scientific, ethical, economic and political dimensions, the OIE needed to develop a detailed vision and strategy incorporating and balancing these dimensions. A permanent working group on animal welfare was established in order to provide guidance to the OIE in its work on the development of science-based standards and guidelines. The Working Group decided to give priority to the welfare of animals used in agriculture and aquaculture, and that, within those groups, the topics of transportation, slaughter for human consumption and killing for disease control purposes would be addressed first. Some guiding principles were approved by the International Committee of OIE Member Countries during the 72nd General Session in May 2004, and these have been followed by four specific guidelines on the priority topics listed above.

  12. Development of indicators for a nationwide cross-sectoral quality assurance procedure for mental health care of patients with schizophrenia, schizotypal and delusional disorders in Germany.

    Science.gov (United States)

    Stegbauer, Constance; Willms, Gerald; Kleine-Budde, Katja; Bramesfeld, Anke; Stammann, Carina; Szecsenyi, Joachim

    2017-10-01

    This paper describes the development of quality indicators for an external statutory and cross-sectoral quality assurance (QA) procedure in the context of the German health care system for adult patients suffering from schizophrenia, schizotypal and delusional disorders (F20-F29). Indicators were developed by a modified RAND/UCLA Appropriateness Method with 1) the compilation of an indicator register based on a systematic literature search and analyses of health care claims data, 2) the selection of indicators by an expert panel that rated them for relevance and for feasibility regarding implementation. Indicators rated positive for both relevance and feasibility formed the final indicator set. 847 indicators were identified by different searches. Out of these, 56 were selected for the indicator register. During the formal consensus process the expert panel recommended another 45 indicators so that a total of 101 indicators needed to be considered by the panel. Of these, 27 indicators rated both relevant and feasible were included in the final set of indicators: this set included 4 indicators addressing structures, 19 indicators addressing processes and 4 indicators addressing outcomes. 17 indicators of the set will be reported by hospitals and 8 by psychiatric outpatient facilities. Two indicators considered to be cross-sectoral will be reported by both sectors. F20-F29 and its treatment show some specific features which so far have not been addressed by any procedure within the statutory QA program of the German health care system. These features include: Schizophrenia and related disorders a) are potentially chronic conditions, b) are mainly treated in outpatient settings, c) require a multi-professional treatment approach and d) are treated regionally in catchment areas. These specific features in combination with the peculiarities of some legal, political and organizational characteristics of the German health care system and its statutory QA program have

  13. Development of a sequential injection-liquid microextraction procedure with GC-FID for analysis of short-chain fatty acids in palm oil mill effluent.

    Science.gov (United States)

    Pruksatrakul, Thapanee; Phoopraintra, Pattamaporn; Wilairat, Prapin; Chaiyen, Pimchai; Chantiwas, Rattikan

    2017-04-01

    Short-chain fatty acids, such as acetic, propionic, butyric, iso-valeric and valeric acids, play an important role in methanogenesis activity for biogas production processes. Thus, simple and rapid procedures for monitoring the levels of short-chain fatty acids are requisite for sustaining biogas production. This work presents the development of a sequential injection-liquid microextraction (SI-LME) procedure with GC-FID analysis for determination of short-chain fatty acids. GC-FID was employed for detection of the short-chain fatty acids. Calibration curves were linear with good coefficients of determination (r 2 >0.999), using methacrylic acid as the internal standard. Limits of quantification (LOQ) were in the range of 0.03-0.19mM. The SI-LME procedure employed tert-butyl methyl ether (TBME) as the extracting solvent. Various SI-LME conditions were investigated and optimized to obtain the highest recovery of extraction. With these optimized conditions, an extraction recovery of the five key short-chain fatty acids of 67-90% was obtained, with less than 2% RSD (n=3). The final SI-LME procedure employed two fluidic zones of TBME with a single aqueous fluidic zone of sample sandwiched between the TBME zones, with 5 cycles of flow reversal at a flow rate of 5µL/s for the extraction process. Intra- and inter-day precision values were 0.5-4.0% RSD and 3.3-4.8% RSD, respectively. Accuracy based on percentage of sample recovery were in the range of 69-96, 102-107, and 82-101% (n=4) for acetic, propionic and butyric acids, respectively. The proposed method was applied for the measurement of short-chain fatty acids in palm oil mill effluents used in biogas production in a factory performing palm oil extraction process. The SI-LME method provides improved extraction performance with high precision, and is both simple and rapid with its economical extraction technique. The SI-LME procedure with GC-FID has strong potential for use as a quality control process for monitoring

  14. Specialty training: Minimizing the impact of procedure upgrade

    International Nuclear Information System (INIS)

    Haberstroh-Timpano, S.

    1991-01-01

    Virginia Power (VP) is currently undertaking a major effort in the area of procedure upgrade. AH station/corporate administrative and station technical procedures are scheduled to be upgraded over the next 5-7 years. Administrative procedures are being revised to create a generic set of station administrative procedures to be used at both sites and by corporate, when corporate staff performs station functions. AH station technical procedures are being revised to include the most current INPO and NRC recommendations, consistent format, a commitment flagging system, and the latest technical and human factors information/processes. The implications for procedure training are tremendous. Although VP has always had a category for Modifications and Experiences in their continuing training programs, this category has been used previously to cover those changes that occur in the plant and within procedures as part of normal operation. Suddenly, Training is faced with the possibility of providing training on all technical, as well as administrative, procedures. The evaluation of training needs and the development of the support materials emphasize the need for direct communications between Training and the procedure groups. The initial attempts at developing this relationship were less than effective. Over the last several months, vp has a combination of methods which involves a hand-in-hand approach that it feels has become quite successful

  15. Connectivity among computer-aided engineering methods, procedures, and tools used in developing the SSC collider magnets

    International Nuclear Information System (INIS)

    Kallas, N.; Jalloh, A.R.

    1992-03-01

    The accomplishment of functional productivity for the computer aided engineering (CAE) environment at the magnet engineering department (ME) of the magnet systems divisions (MSD) at the Superconducting Super Collider Laboratory (SSCL) involves most of the basic aspects of information engineering. It is highly desirable to arrive at a software and hardware topology that offers total, two-way (back and forth), automatic and direct software and hardware connectivity among computer-aided design and drafting (CADD), analysis codes, and office automation tools applicable to the disciplines involved. This paper describes the components, data flow, and practices employed in the development of the CAE environment from a systems engineering aspect rather than from the analytical angle. When appropriate, references to case studies are made in order to demonstrate the connectivity of the techniques used

  16. Development of a relatively cheap and simple automated separation system for a routine separation procedure based on extraction chromatography

    International Nuclear Information System (INIS)

    Petro Zoriy; Reinhold Flucht; Mechthild Burow; Peter Ostapczuk; Reinhard Lennartz; Myroslav Zoriy

    2010-01-01

    A robust analytical method has been developed in our laboratory for the separation of radionuclides by means of extraction chromatography using an automated separation system. The proposed method is both cheap and simple and provides the advantageous, rapid and accurate separation of the element of interest. The automated separation system enables a shorter separation time by maintaining a constant flow rate of solution and by avoiding clogging or bubbling in the chromatographic column. The present separation method was tested with two types of samples (water and urine) using UTEVA-, TRU- and Sr-specific resins for the separation of U, Th, Am, Pu and Sr. The total separation time for one radionuclide ranged from 60 to 100 min with the separation yield ranging from 68 to 98% depending on the elements separated. We used ICP-QMS, multi-low-level counter and alpha spectroscopy to measure the corresponding elements. (author)

  17. [Opportunity for development of laparoscopic procedures in the hospital setting: costs and benefits for the surgical unit].

    Science.gov (United States)

    Vino, F; Trerotoli, P; Serio, G

    2002-01-01

    Physician are induced, by technical development, to demand new devices and instruments and to introduce new method for diagnosis and treatment. In order to do a right economic planning in public health, it's necessary to evaluate costs of technologies, because sometimes there isn't neither a right plan for acquisition nor an efficient control system. One the most stressed medical branch by innovative technologies is the surgery, in particular after the coming of laparoscopic surgery. The will to do, in every way laparoscopic approach, induces to evaluate costs of this surgery, specially cholecystectomy, that is identified by four specific DRGs. In this paper we compare laparotomic versus laparoscopic cholecystectomy in terms of costs and length of stay; the break-even analysis has been performed to determine the number of laparoscopic operations necessary to balance the costs.

  18. Procedure for Development and Establishment of Indicators to Measure the Effectiveness of Customs Authority and its Departments

    Directory of Open Access Journals (Sweden)

    July G. Kishinskiy

    2016-12-01

    Full Text Available In this article author analyzes the organizational and legal framework for the development and establishment of indicators for assessing the effectiveness of the activities of the customs body of the Russian Federation and its structural divisions at the present stage. In the conclusion author states that the current performance indicators for the performance of customs authorities and their structural units are a system of great importance in the practical activities of customs officials, cover the implementation of the strategic goal of the customs service, most of the tasks and functions established by the state for customs officers and are "Indicator" of their achievement, allowing to identify "weaknesses" in the current work and to take new accurate and effective management solutions.

  19. Development of a procedure for qualitative and quantitative evaluation of human factors as a part of probabilistic safety assessments of nuclear power plants. Part B. Technical documentation

    International Nuclear Information System (INIS)

    Richei, A.

    1998-01-01

    As international studies have shown, accidents in plants are increasingly caused by combinations of technical failures and human errors. Therefore careful investigations of man-machine-interactions to determine human reliability are gaining importance worldwide. Regarding nuclear power plants such investigations are usually carried out within the scope of probabilistic safety assessments. A great number of procedures to evaluate human factors has been developed up to now. However, none of them is able to take into account the whole spectrum of requirements - as for instance transferability of date to other plants, analysis of weak points, and evaluation of cognitive tasks - for a complete and reliable probabilistic safety assessment. Based on an advanced model for a man-machine-system, the Human Error Rate Assessment and Optimizing System (HEROS) and a corresponding expert system of the same name are introduced. This expert system enables the quantification of human error probabilities for plant operator actions on the one hand and is also capable of providing quantitative statements regarding the optimization of man-machine-system in terms of human error probability minimization on the other one. Three relevant evaluation levels, i.e. 'Management Structure', 'Working Environment' and 'Man-Machine-Interface', are derived from a model of the man-machine-system. Linguistic variables are assigned to all performance shaping factors at these levels. These variables are used to establish a rule-based expert system. The knowledge bases of this system are represented by rules. Processing of these rules is carried out by means of the fuzzy set theory, after provision of relevant data for a particular personal action to be evaluated. This procedure enables a simple and effective use of ergonomic studies as the relevant database, which is also transferable to other plants with any design. The expert system consist in total of 16 rule bases in which all ascertainable and

  20. Prevalence of Infraumbilical Adhesions in Women With Previous Laparoscopy

    Science.gov (United States)

    Ku, Lowell; Wong, Herb; Liu, C. Y.; Phelps, John Y.

    2007-01-01

    Background and Objectives: The aim of this study is to evaluate the prevalence of intraabdominal adhesions to the umbilicus following gynecologic laparoscopy through an umbilical incision. Methods: A retrospective review was performed of all gynecologic laparoscopic procedures in a private practice setting to identify patients with a repeat laparoscopy who had a history of a previous laparoscopy through an umbilical incision. Patients with a history of other surgeries were excluded. All repeat laparoscopies used a left upper quadrant entry technique where the abdominal cavity was surveyed for adhesions. We also reviewed adverse events attributable to the left upper quadrant entry approach. Results: We identified 151 patients who underwent a second laparoscopy and had a previous umbilical scar. Thirty-two of the 151 (21.2%) patients with a history of a laparoscopy had evidence of adhesions to the umbilical undersurface. No adverse events or injuries were attributed to the left upper quadrant entry technique. Conclusions: Adhesions to the umbilical undersurface occur in 21.2% of patients who have undergone a prior laparoscopy through an umbilical incision. For this reason, we recommend an alternate location for entry in patients with an umbilical scar from a previous laparoscopy. PMID:17651555

  1. Improvements to previous algorithms to predict gene structure and isoform concentrations using Affymetrix Exon arrays

    Directory of Open Access Journals (Sweden)

    Aramburu Ander

    2010-11-01

    Full Text Available Abstract Background Exon arrays provide a way to measure the expression of different isoforms of genes in an organism. Most of the procedures to deal with these arrays are focused on gene expression or on exon expression. Although the only biological analytes that can be properly assigned a concentration are transcripts, there are very few algorithms that focus on them. The reason is that previously developed summarization methods do not work well if applied to transcripts. In addition, gene structure prediction, i.e., the correspondence between probes and novel isoforms, is a field which is still unexplored. Results We have modified and adapted a previous algorithm to take advantage of the special characteristics of the Affymetrix exon arrays. The structure and concentration of transcripts -some of them possibly unknown- in microarray experiments were predicted using this algorithm. Simulations showed that the suggested modifications improved both specificity (SP and sensitivity (ST of the predictions. The algorithm was also applied to different real datasets showing its effectiveness and the concordance with PCR validated results. Conclusions The proposed algorithm shows a substantial improvement in the performance over the previous version. This improvement is mainly due to the exploitation of the redundancy of the Affymetrix exon arrays. An R-Package of SPACE with the updated algorithms have been developed and is freely available.

  2. ¡Cocinar Para Su Salud! Development of a Culturally Based Nutrition Education Curriculum for Hispanic Breast Cancer Survivors Using a Theory-Driven Procedural Model.

    Science.gov (United States)

    Aycinena, Ana Corina; Jennings, Kerri-Ann; Gaffney, Ann Ogden; Koch, Pamela A; Contento, Isobel R; Gonzalez, Monica; Guidon, Ela; Karmally, Wahida; Hershman, Dawn; Greenlee, Heather

    2017-02-01

    We developed a theory-based dietary change curriculum for Hispanic breast cancer survivors with the goal of testing the effects of the intervention on change in dietary intake of fruits/vegetables and fat in a randomized, clinical trial. Social cognitive theory and the transtheoretical model were used as theoretical frameworks to structure curriculum components using the Nutrition Education DESIGN Procedure. Formative assessments were conducted to identify facilitators and barriers common to Hispanic women and test the degree of difficulty and appropriateness of program materials. Focus groups provided valuable insight and informed preimplementation modifications to the dietary program. The result was a systematically planned, evidence-based, culturally tailored dietary intervention for Hispanic breast cancer survivors, ¡Cocinar Para Su Salud! (Cook for Your Health!). The methodology described here may serve as a framework for the development of future dietary interventions among diverse and minority populations. Short- and long-term study results will be reported elsewhere.

  3. Development of procedures for spectrometer brand Spectral Products to capture spectra of incoherent optical radiation for the Laboratorio de Fotonica y Tecnologia Laser Aplicada

    International Nuclear Information System (INIS)

    Arias Avendano, Fabio Andres

    2008-01-01

    The procedure to capture spectra of incoherent optical radiation for the Laboratorio de Fotonica y Tecnologia Laser Aplicada (LAFTLA), of the Escuela de Ingenieria Electrica de la Universidad de Costa Rica is developed through the use of a spectrometer brand Spectral Products. The thorough understanding of manuals spectrometer brand Spectral Products was necessary for the satisfactory development of the project. Spectrometer and the card National Instruments are installed and run both devices with a montage of suitable laboratory. Two catches of spectrum for two different sources of optical radiation are performanced, since damages to the files .ddl precluded that the SM 240 spectrometer worked properly to take more catches to other sources of optical radiation. A final report containing the two catches is produced with the respective analysis. (author) [es

  4. Development and validation of a procedure for the determination of minoxidil in hair-regrowth formulations using two variants of capillary zone electrophoresis.

    Science.gov (United States)

    Patterson, S C; Ramstad, T; Mills, K A

    2005-01-01

    A high performance capillary electrophoresis method was developed and validated for purity assessment of minoxidil bulk drug and for determination of minoxidil in Rogaine. The principal use of the method was in analyzing illicit minoxidil-containing hair-regrowth samples. Although validated for Rogaine, the procedure proved equally viable on illicit minoxidil-containing preparations. The developed method fulfilled the goal of providing an orthogonal technique to HPLC for confirmation of the presence of minoxidil in these imitations. The method was validated on two instruments, one utilizing EK injection, the other gravity injection. It is selective for minoxidil, which is separated from known process impurities and the single degradation impurity. Validation figures of merit for linearity/recovery (accuracy) and precision were in accordance with current expectations for method validation.

  5. FFTF operations procedures preparation guide. Revision 2

    International Nuclear Information System (INIS)

    1976-12-01

    The Guide is intended to provide guidelines for the initial preparation of FFTF Operating Procedures. The Procedures Preparation Guide was developed from the plan presented and approved in the FFTF Reactor Plant Procedures Plan, PC-1, Revision 3

  6. Child healthcare nurses believe that bilingual children show slower language development, simplify screening procedures and delay referrals.

    Science.gov (United States)

    Nayeb, Laleh; Wallby, Thomas; Westerlund, Monica; Salameh, Eva-Kristina; Sarkadi, Anna

    2015-02-01

    A significant number of children living in Sweden are bilingual, but how language screening is performed in this group is unknown. We investigated child healthcare nurses' perceptions of the language screening of bilingual children aged 30-36 months, together with their clinical practices. An online questionnaire was completed by 863 nurses who performed language screening of bilingual children in Sweden at least once a month, corresponding to 89% of the target population. Cox regression identified predictors of the nurses' tendency to simplify the screening of bilingual children. The nurses reported a greater lack of confidence and more difficulties in interpreting screening outcomes for bilingual than monolingual children (p bilingual children and 74% postponed referrals to speech and language services, basing these adaptations on their perceptions of the children's Swedish language skills (p bilingual children, and this was the strongest predictor of simplified screening practices (RR=2.00, 95% CI 1.44-2.77). Child healthcare nurses need easily accessible information and clear guidelines on the language development of bilingual children to ensure that bilingual and monolingual children receive equitable language screening services. ©2014 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

  7. Development of quality control procedures for mass produced and released oriental fruit flies, Bactrocera philippinensis for SIT programmes

    International Nuclear Information System (INIS)

    Resilva, Sotero S.; Obra, Glenda B.

    2001-01-01

    This report summarizes different quality control tests necessary to monitor the behavior of oriental fruit fly, B. philippinensis from the mass rearing facility to the release site. Results of routine quality control tests revealed that pupal size, emergence, fliers, sex ration, stress tests, mating index and fertility tests were all above satisfactory levels in pre-and post-irradiation treatment. Tests at the release site showed similar findings except for mating index where poor performance of flies were observed. Fertility and fecundity tests indicate that complete sterility of OFF was achieved at dose ranging from 68-104 Gy. Standard specifications required for weekly and monthly quality control tests was not yet established because release of sterile flies in Guimaras started only last April, 2001. In determining eye color changes in relation to physiological development, eye appearance of the pupae is dark yellowish brown (HUE 10 YR 3/6) at 7 days old where irradiation is to be applied for sterilization. Cross correlation of results showed large pupae had great advantage over medium and small pupae in terms of flight dispersal. Poor emergence and fliers of small pupae were observed when irradiated and chilled for 24 hours. However, no significant difference was observed on mating preference, longevity and fertility among the three pupal size groups. (Author)

  8. Development and optimization of the SPE procedure for determination of pharmaceuticals in water samples by HPLC-diode array detection.

    Science.gov (United States)

    Mutavdzić Pavlović, Dragana; Babić, Sandra; Dolar, Davor; Asperger, Danijela; Kosutić, Kresimir; Horvat, Alka J M; Kastelan-Macan, Marija

    2010-02-01

    This paper focuses on the investigation of different types of SPE sorbents for the preconcentration of eight veterinary pharmaceuticals from water samples. The pharmaceuticals studied were sulfamethazine, sulfadiazine, sulfaguanidine, trimethoprim, oxytetracycline, enrofloxacin, norfloxacin and penicillin G/procaine. Five different SPE materials (Strata-X, Strata-X-C, Strata SDB-L, Strata C8 and Strata C18) from Phenomenex were compared with Oasis HLB with a view to obtaining the best cartridges for all pharmaceuticals investigated. Extraction efficiency was determined by HPLC with diode array detection (DAD). HPLC-DAD separation and quantification of the selected pharmaceuticals were carried out under gradient elution by a binary mixture of 0.01 M oxalic acid and ACN based on cyano modified column (LiChrosphere 100 CN) from Merck. Strata-X provided the best results in the preconcentration of 100 mL water samples, yielding average pharmaceutical recoveries of higher than 90%, except for sulfaguanidine (76.1%). The developed Strata-X-HLPC-DAD method was validated and applied, for the efficient investigation of reverse osmosis/nanofiltration membranes and for the removal of these eight pharmaceuticals from the production wastewater samples. NF90 and XLE membranes were shown to be the best for the rejection of all investigated pharmaceuticals.

  9. Balance and bilateral skills of selected previously disadvantaged ...

    African Journals Online (AJOL)

    Balance and bilateral skills of selected previously disadvantaged children aged 9 to 12 years. Eileen K Africa, Karel J Van Deventer. Abstract. The main aim of the study was to design an appropriate motor skills development programme that could be implemented in any primary school to improve the fundamental motor ...

  10. 24 CFR 1710.552 - Previously accepted state filings.

    Science.gov (United States)

    2010-04-01

    ... of Substantially Equivalent State Law § 1710.552 Previously accepted state filings. (a) Materials... and contracts or agreements contain notice of purchaser's revocation rights. In addition see § 1715.15..., unless the developer is obligated to do so in the contract. (b) If any such filing becomes inactive or...

  11. Executive Function in Previously Institutionalized Children.

    Science.gov (United States)

    Merz, Emily C; Harlé, Katia M; Noble, Kimberly G; McCall, Robert B

    2016-06-01

    In studies of children adopted from institutions, being raised in an institution has been associated consistently with an increased risk of persistent cognitive, academic, and social-emotional problems. These findings raise questions about the neurocognitive mechanisms that contribute to these negative outcomes. Theory and models based on studies of animals indicate that development of the prefrontal cortex (PFC) and executive function (EF) may be particularly susceptible to environmental influences during early childhood. In this article, we review recent studies of postinstitutionalized children that examined EF components such as inhibitory control, working memory, shifting, and planning. We then describe emerging research on the structure and function of the PFC. Converging evidence suggests both EF difficulties and alterations in development of the PFC following early institutionalization. We conclude by discussing possible explanations for these findings and implications for prevention and intervention, and by offering suggestions for ongoing research.

  12. Development of a solid phase extraction procedure for HPLC-DAD determination of several angiotensin II receptor antagonists in human urine using mixture design.

    Science.gov (United States)

    Ferreirós, N; Iriarte, G; Alonso, R M; Jiménez, R M

    2007-10-15

    The optimisation of a solid phase extraction procedure involves several variables whose influence has been widely studied. However, in most cases, only process variables are taken into account. In this work, the influence of those process variables together with the fact of using mixtures of solvents during the elution step of the solid phase extraction of four angiotensin II receptor antagonist drugs has been studied. Since the influence on the extraction efficiency of several process variables were simultaneously tested, a D-optimal design was constructed. The composition of the elution solvent (a mixture of methanol, acetonitrile, ethanol and acetone at different proportions from 0 to 100% each solvent), the percentage and pH of the buffer solution added to the urine samples at the beginning of the extraction procedure; the percentage of the organic component and the volume of the washing solution, the drying time and the volume of the elution solvent were the studied variables. The chromatographic separation was carried out by gradient elution mode with 0.026% trifluoroacetic acid (TFA) in the organic phase and 0.031% TFA in the aqueous phase using an Atlantis dC18, 100mmx3.9mm I.D. chromatographic column at a flow rate of 1mL/min and a column temperature of 35+/-0.2 degrees C. For detection a diode array detector set at 232nm was used. The extraction procedure for spiked human urine samples was developed using C8 cartridges, phosphate buffer pH 6.8 as conditioning agent, a drying step of 10min, a washing step with methanol-phosphate buffer (20:80, v/v) and methanol as eluent. Recovery percentages obtained: 84% for eprosartan, 74% for telmisartan, 74% for irbesartan and 89% for valsartan allow the determination of these drugs concentration levels in urine.

  13. Incidence of previously undetected disease in routine paediatric otolaryngology admissions.

    Science.gov (United States)

    Zeitoun, H; Robinson, P

    1996-06-01

    The process of clerking routine pre-operative admissions involves the house officer taking a full medical history and performing a full physical examination. The diagnostic yield is thought to be low, and the educational value to the house officer is also small. This study addresses the question as to whether routine physical examination is always indicated. One hundred and nine children admitted for routine Otolaryngology procedures were prospectively studied to identify the importance of examination in the pre-operative assessment of patients. The results showed that 51 per cent of the children admitted had risk factors. The medical history was sufficient to identify these risk factors in all patients with the exception of one cardiac condition. This study concludes that a suitable alternative to the current process of clerking such as a standardized nurse history could be safely and efficiently undertaken. Eliminating the tiny percentage of previously unrecognized disease would be a prerequisite for such a change.

  14. Percutaneous endoscopic jejunostomy in a patient with previous esophagectomy.

    Science.gov (United States)

    de la Torre, R A; Scott, J S; Unger, S W

    1991-04-01

    Establishment of a percutaneous endoscopic jejunostomy via direct jejunal puncture was accomplished in a 45-year-old woman five years after a partial esophagectomy with cervical esophagogastrostomy for adenocarcinoma of the esophagus. The patient had recurrence of the cancer at the anastomotic site with subsequent inability to eat, necessitating a feeding tube for prolonged enteral nutrition. Although percutaneous puncture of the jejunum has been previously described, it has been limited to patients who had undergone partial or complete gastrectomies with Bilroth II anastomoses. This case report of direct endoscopic jejunal tube placement in a patient after esophagectomy further establishes this procedure as a viable alternative to surgically placed feeding tubes in patients with altered gastric anatomy.

  15. [Potential of cooperative learning in project development : Relevance of cooperative participation procedure for the further development of generation-appropriate accomodation in structurally weak rural areas].

    Science.gov (United States)

    Kaufmann, Gerd; Frankenberg, Olga; Sommer, Ralf-Rüdiger; Jost, Annemarie

    2017-04-01

    A joint initiative of existing senior care organizations, the municipality of Meyenburg and the state of Brandenburg was further developed by affiliation of an institute of the Brandenburg University of Technology Cottbus-Senftenberg (ABV) in cooperation with members of the architecture and social work departments in 2014. A cooperative process between different players was central to create an appropriate structure of services for this region. Cooperative projects are necessary to establish new forms of generation-appropriate living and care concepts in rural areas. Cooperative learning methods are needed to develop new forms of generation-appropriate living and care concepts in rural areas, which take the diversity of elderly people, the rural context, intergenerational residential arrangements and affordable accommodation that meets the requirements of the social security system into account. Furthermore, the project had to reflect the recent developments of the German care insurance. The article describes the participatory methods, the coordination process and the resulting concept.

  16. Ensuring due process in the IACUC and animal welfare setting: considerations in developing noncompliance policies and procedures for institutional animal care and use committees and institutional officials.

    Science.gov (United States)

    Hansen, Barbara C; Gografe, Sylvia; Pritt, Stacy; Jen, Kai-Lin Catherine; McWhirter, Camille A; Barman, Susan M; Comuzzie, Anthony; Greene, Molly; McNulty, Justin A; Michele, Daniel Eugene; Moaddab, Naz; Nelson, Randall J; Norris, Karen; Uray, Karen D; Banks, Ron; Westlund, Karin N; Yates, Bill J; Silverman, Jerald; Hansen, Kenneth D; Redman, Barbara

    2017-10-01

    Every institution that is involved in research with animals is expected to have in place policies and procedures for the management of allegations of noncompliance with the Animal Welfare Act and the U.S. Public Health Service Policy on the Humane Care and Use of Laboratory Animals. We present here a model set of recommendations for institutional animal care and use committees and institutional officials to ensure appropriate consideration of allegations of noncompliance with federal Animal Welfare Act regulations that carry a significant risk or specific threat to animal welfare. This guidance has 3 overarching aims: 1 ) protecting the welfare of research animals; 2 ) according fair treatment and due process to an individual accused of noncompliance; and 3 ) ensuring compliance with federal regulations. Through this guidance, the present work seeks to advance the cause of scientific integrity, animal welfare, and the public trust while recognizing and supporting the critical importance of animal research for the betterment of the health of both humans and animals.-Hansen, B. C., Gografe, S., Pritt, S., Jen, K.-L. C., McWhirter, C. A., Barman, S. M., Comuzzie, A., Greene, M., McNulty, J. A., Michele, D. E., Moaddab, N., Nelson, R. J., Norris, K., Uray, K. D., Banks, R., Westlund, K. N., Yates, B. J., Silverman, J., Hansen, K. D., Redman, B. Ensuring due process in the IACUC and animal welfare setting: considerations in developing noncompliance policies and procedures for institutional animal care and use committees and institutional officials. © FASEB.

  17. New design procedure development of future reactor critical power estimation. (1) Practical design-by-analysis method for BWR critical power design correlation

    International Nuclear Information System (INIS)

    Yamamoto, Yasushi; Mitsutake, Toru

    2007-01-01

    For present BWR fuels, the full mock-up thermal-hydraulic test, such as the critical power measurement test, pressure drop measurement test and so on, has been needed. However, the full mock-up test required the high costs and large-scale test facility. At present, there are only a few test facilities to perform the full mock-up thermal-hydraulic test in the world. Moreover, for future BWR, the bundle size tends to be larger, because of reducing the plant construction costs and minimizing the routine check period. For instance, AB1600, improved ABWR, was proposed from Toshiba, whose bundle size was 1.2 times larger than the conventional BWR fuel size. It is too expensive and far from realistic to perform the full mock-up thermal-hydraulic test for such a large size fuel bundle. The new design procedure is required to realize the large scale bundle design development, especially for the future reactor. Therefore, the new design procedure, Practical Design-by-Analysis (PDBA) method, has been developed. This new procedure consists of the partial mock-up test and numerical analysis. At present, the subchannel analysis method based on three-fluid two-phase flow model only is a realistic choice. Firstly, the partial mock-up test is performed, for instance, the 1/4 partial mock-up bundle. Then, the first-step critical power correlation coefficients are evaluated with the measured data. The input data, such as the spacer effect model coefficient, on the subchannel analysis are also estimated with the data. Next, the radial power effect on the critical power of the full-bundle size was estimated with the subchannel analysis. Finally, the critical power correlation is modified by the subchannel analysis results. In the present study, the critical power correlation of the conventional 8x8 BWR fuel was developed with the PDBA method by 4x4 partial mock-up tests and the subchannel analysis code. The accuracy of the estimated critical power was 3.8%. The several themes remain to

  18. Combined thoracoscopic and laparoscopic robotic-assisted minimally invasive esophagectomy using a four-arm platform: experience, technique and cautions during early procedure development.

    Science.gov (United States)

    Sarkaria, Inderpal S; Rizk, Nabil P; Finley, David J; Bains, Manjit S; Adusumilli, Prasad S; Huang, James; Rusch, Valerie W

    2013-05-01

    This study reports an early, single-institution experience of combined thoracoscopic and laparoscopic robotic-assisted minimally invasive esophagectomy (RAMIE) using a four-arm robotic platform, with special attention given to the pitfalls and complications during procedure development. We conducted a prospective, single-cohort, observational study of patients undergoing RAMIE at a single institution. A total of 21 patients (median age, 62 years [range, 37-83 years]) underwent RAMIE with a four-arm robotic platform (17 by Ivor Lewis and 4 by McKeown). Of the patients, 17 (81%) had a complete (R0) resection, and 16 (76%) received induction treatment, the majority (14/21 [67%]) with combined chemoradiation. The median operative time was 556 min (range, 395-807 min), which decreased to 414 min (range, 405-543 min) for the last 5 cases in the series. The median estimated blood loss was 307 cm(3) (range, 200-500 cm(3)), and the median length of hospital stay was 10 days (range, 7-70 days). The median number of lymph nodes resected was 20 (range, 10-49). Five (24%) patients were converted to open procedures. Five patients (24%) had major complications. One (5%) died of complications on postoperative Day 70, and 3 (14%) had clinically significant anastomotic leaks (Grade II or greater, by Common Terminology Criteria for Adverse Events version 3.0). Three patients (14%) in this early experience developed airway fistulas. While four-arm RAMIE may offer advantages over standard minimally invasive esophagectomy approaches, its adoption in a structured program, with critical evaluation of adverse events and subsequent adjustment of technique, is paramount to maximize patient safety, minimize complications and improve the conduct of operation early in the learning curve. Particular technical consideration should be given to prevention of airway complications.

  19. Development of an analytical procedure for the determination of polybrominated diphenyl ethers in environmental water samples by GC-ICP-MS.

    Science.gov (United States)

    Novak, Petra; Zuliani, Tea; Milačič, Radmila; Ščančar, Janez

    2014-05-27

    Polybrominated diphenyl ethers (PBDEs) are flame retardants, which due to their widespread use are frequently present as pollutants in the environment. In the EU Water Framework Directive (WFD) six PBDE congeners (BDE 28, BDE47, BDE 99, BDE 100, BDE 153 and BDE 154) are listed as priority substances. The uncertainty of the analytical method used for their determination in water samples at environmental quality standard (EQS) level (0.5 ng L(-1) for the ΣPBDEs) should be equal or less than 50% and the limit of quantification (LOQ) for ΣPBDEs below 0.15 ng L(-1). To meet these requirements, an analytical procedure for the determination of these six PBDEs in environmental water samples by gas chromatography-inductively coupled plasma mass spectrometry (GC-ICP-MS) was developed. The acidification of water samples to pH 2 maintained the stability of PBDEs for at least 20 days. The use of Tris-citrate buffer enabled efficient desorption of PBDEs from suspended particulate matter (SPM) and humic acids (HA), and their further quantitative solvent extraction into 2 mL of iso-octane. When 300 mL of water sample was used for analysis and the organic phase concentrated to 25 μL, the expanded uncertainty for determination of PBDEs at EQS level was found to be around 40% (a coverage factor for a confidence level of 95%, k=2), and the LOQ for the ΣPBDEs 0.109 ng L(-1). Finally, to demonstrate the applicability of the newly developed GC-ICP-MS procedure, PBDEs were determined in river and sea water samples. Copyright © 2014 Elsevier B.V. All rights reserved.

  20. Tubal anastomosis after previous sterilization: a systematic review.

    Science.gov (United States)

    van Seeters, Jacoba A H; Chua, Su Jen; Mol, Ben W J; Koks, Carolien A M

    2017-05-01

    Female sterilization is one of the most common contraceptive methods. A small number of women, however, opt for reversal of sterilization procedures after they experience regret. Procedures can be performed by laparotomy or laparoscopy, with or without robotic assistance. Another commonly utilized alternative is IVF. The choice between surgery and IVF is often influenced by reimbursement politics for that particular geographic location. We evaluated the fertility outcomes of different surgical methods available for the reversal of female sterilization, compared these to IVF and assessed the prognostic factors for success. Two search strategies were employed. Firstly, we searched for randomized and non-randomized clinical studies presenting fertility outcomes of sterilization reversal up to July 2016. Data on the following outcomes were collected: pregnancy rate, ectopic pregnancy rate, cost of the procedure and operative time. Eligible study designs included prospective or retrospective studies, randomized controlled trials, cohort studies, case-control studies and case series. No age restriction was applied. Exclusion criteria were patients suffering from tubal infertility from any other reason (e.g. infection, endometriosis and adhesions from previous surgery) and studies including sterilization reversal procedures were then evaluated: female age, BMI and duration and method of sterilization. Secondly, we searched for randomized and non-randomized clinical studies that compared reversal of sterilization to IVF and evaluated them for pregnancy outcomes and cost effectiveness. We included 37 studies that investigated a total of 10 689 women. No randomized controlled trials were found. Most studies were retrospective cohort studies of a moderate quality. The pooled pregnancy rate after sterilization reversal was 42-69%, with heterogeneity seen from the different methods utilized. The reported ectopic pregnancy rate was 4-8%. The only prognostic factor affecting the

  1. Formalizing physical security procedures

    NARCIS (Netherlands)

    Meadows, C.; Pavlovic, Dusko

    Although the problems of physical security emerged more than 10,000 years before the problems of computer security, no formal methods have been developed for them, and the solutions have been evolving slowly, mostly through social procedures. But as the traffic on physical and social networks is now

  2. Rates of induced abortion in Denmark according to age, previous births and previous abortions

    Directory of Open Access Journals (Sweden)

    Marie-Louise H. Hansen

    2009-11-01

    Full Text Available Background: Whereas the effects of various socio-demographic determinants on a woman's risk of having an abortion are relatively well-documented, less attention has been given to the effect of previous abortions and births. Objective: To study the effect of previous abortions and births on Danish women's risk of an abortion, in addition to a number of demographic and personal characteristics. Data and methods: From the Fertility of Women and Couples Dataset we obtained data on the number of live births and induced abortions by year (1981-2001, age (16-39, county of residence and marital status. Logistic regression analysis was used to estimate the influence of the explanatory variables on the probability of having an abortion in a relevant year. Main findings and conclusion: A woman's risk of having an abortion increases with the number of previous births and previous abortions. Some interactions were was found in the way a woman's risk of abortion varies with calendar year, age and parity. The risk of an abortion for women with no children decreases while the risk of an abortion for women with children increases over time. Furthermore, the risk of an abortion decreases with age, but relatively more so for women with children compared to childless women. Trends for teenagers are discussed in a separate section.

  3. Optimization of hydraulic machinery by exploiting previous successful designs

    Energy Technology Data Exchange (ETDEWEB)

    Kyriacou, S A; Giannakoglou, K C [National Technical University of Athens, Parallel CFD and Optimization Unit, PO Box 64069, Athens 15710 (Greece); Weissenberger, S; Grafenberger, P, E-mail: stelios.Kyriacou@gmail.co [Andritz HYDRO, RD, Lunzerstrasse 78, 4031 Linz (Austria)

    2010-08-15

    A design-optimization method for hydraulic machinery is proposed. Optimal designs are obtained using the appropriate CFD evaluation software driven by an evolutionary algorithm which is also assisted by artificial neural networks used as surrogate evaluation models or metamodels. As shown in a previous IAHR paper by the same authors, such an optimization method substantially reduces the CPU cost, since the metamodels can discard numerous non-promising candidate solutions generated during the evolution, at almost negligible CPU cost, without evaluating them by means of the costly CFD tool. The present paper extends the optimization method of the previous paper by making it capable to accommodate and exploit pieces of useful information archived during previous relevant successful designs. So, instead of parameterizing the geometry of the hydraulic machine components, which inevitably leads to many design variables, enough to slow down the design procedure, in the proposed method all new designs are expressed as weighted combinations of the archived ones. The archived designs act as the design space bases. The role of the optimization algorithms is to find the set (or sets, for more than one objectives, where the Pareto front of non-dominated solutions is sought) of weight values, corresponding to the hydraulic machine configuration(s) with optimal performance. Since the number of weights is much less that the number of design variables of the conventional shape parameterization, the design space dimension reduces and the CPU cost of the metamodel-assisted evolutionary algorithm is much lower. The design of a Francis runner is used to demonstrate the capabilities of the proposed method.

  4. Material control assessment procedure

    International Nuclear Information System (INIS)

    Adams, R.W.; Spogen, L.R.

    1977-06-01

    The material control system assessment procedure being developed by the Lawrence Livermore Laboratory for the U.S. Nuclear Regulatory Commission is reviewed. It consists of five major sections: Target Identification, Adversary Sequence and Simuli Generation, Material Control System Response Determination, Safeguard System Outcome Determination, and Safeguard System Utility Determination. When adopted, this procedure will reduce safeguards licensing problems by providing compatibility with future performance based regulations, explicit evaluation rules and requirements, well-defined trade-off structures, and user-oriented and systematic evaluation and design tools

  5. Surface cleanliness measurement procedure

    Science.gov (United States)

    Schroder, Mark Stewart; Woodmansee, Donald Ernest; Beadie, Douglas Frank

    2002-01-01

    A procedure and tools for quantifying surface cleanliness are described. Cleanliness of a target surface is quantified by wiping a prescribed area of the surface with a flexible, bright white cloth swatch, preferably mounted on a special tool. The cloth picks up a substantial amount of any particulate surface contamination. The amount of contamination is determined by measuring the reflectivity loss of the cloth before and after wiping on the contaminated system and comparing that loss to a previous calibration with similar contamination. In the alternative, a visual comparison of the contaminated cloth to a contamination key provides an indication of the surface cleanliness.

  6. Previously infertile couples and the newborn intensive care unit.

    Science.gov (United States)

    Lind, R F; Pruitt, R L; Greenfeld, D

    1989-05-01

    Having a newborn child admitted to a newborn intensive care unit can be a traumatic experience for parents; however, parents who previously have been infertile face unique problems in coping with this situation. The authors discuss the difficulties parents must overcome in resolving their crises and in developing a good relationship with their child, or, in some cases, coming to terms with the child's death or ongoing disability. In addition, the authors offer suggestions for effective social work intervention.

  7. Assisted Medical Procedures (AMP) Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Documentation and Development: The AMP was initially being developed as part the Advanced Integrated Clinical System (AICS)-Guided Medical Procedure System for the...

  8. THE VALUE OF REMOVING DAILY OBSTACLES VIA EVERYDAY PROBLEM SOLVING THEORY: DEVELOPING AN APPLIED NOVEL PROCEDURE TO INCREASE SELF-EFFICACY FOR EXERCISE

    Directory of Open Access Journals (Sweden)

    Daniele eArtistico

    2013-01-01

    Full Text Available The objective of the study was to develop a novel procedure to increase self-efficacy for exercise. Gains in one’s ability to resolve day-to-day obstacles for entering an exercise routine were expected to cause an increase in self-efficacy for exercise. Fifty-five sedentary participants (did not exercise regularly for at least 4 months prior to the study who expressed an intention to exercise in the near future were selected for the study. Participants were randomly assigned to one of three conditions: 1 an Experimental Group in which they received a problem-solving training session to learn new strategies for solving day-to-day obstacles that interfere with exercise, 2 a Control Group with Problem Solving Training which received a problem solving training session focused on a typical day-to-day problem unrelated to exercise, or 3 a Control Group which did not receive any problem-solving training. Assessment of obstacles to exercise and perceived self-efficacy for exercise were conducted at baseline; perceived self-efficacy for exercise was reassessed post-intervention (one week later. No differences in perceived challenges posed by obstacles to exercise or self-efficacy for exercise were observed across groups at baseline. The Experimental Group reported greater improvement in self-efficacy for exercise compared to the Control Group with Training (p < 0.01 and the Control Group (p < 0.01. Results of this study suggest that a novel procedure that focuses on removing obstacles to intended planned fitness activities is effective in increasing self-efficacy to engage in exercise among sedentary adults. Implications of these findings for use in applied settings and treatment studies are discussed.

  9. A new development of the dynamic procedure in large-eddy simulation based on a Finite Volume integral approach. Application to stratified turbulence

    Science.gov (United States)

    Denaro, Filippo Maria; de Stefano, Giuliano

    2011-10-01

    A Finite Volume-based large-eddy simulation method is proposed along with a suitable extension of the dynamic modelling procedure that takes into account for the integral formulation of the governing filtered equations. Discussion about the misleading interpretation of FV in some literature is addressed. Then, the classical Germano identity is congruently rewritten in such a way that the determination of the modelling parameters does not require any arbitrary averaging procedure and thus retains a fully local character. The numerical modelling of stratified turbulence is the specific problem considered in this study, as an archetypal of simple geophysical flows. The original scaling formulation of the dynamic sub-grid scale model proposed by Wong and Lilly (Phys. Fluids 6(6), 1994) is suitably extended to the present integral formulation. This approach is preferred with respect to traditional ones since the eddy coefficients can be independently computed by avoiding the addition of unjustified buoyancy production terms in the constitutive equations. Simple scaling arguments allow us not to use the equilibrium hypothesis according to which the dissipation rate should equal the sub-grid scale energy production. A careful a priori analysis of the relevance of the test filter shape as well as the filter-to-grid ratio is reported. Large-eddy simulation results are a posteriori compared with a reference pseudo-spectral direct numerical solution that is suitably post-filtered in order to have a meaningful comparison. In particular, the spectral distribution of kinetic and thermal energy as well as the viscosity and diffusivity sub-grid scale profiles are illustrated. The good performances of the proposed method, in terms of both evolutions of global quantities and statistics, are very promising for the future development and application of the method.

  10. Pandemic risk prevention in European countries: role of the ECDC in preparing for pandemics. Development and experience with a national self-assessment procedure, 2005-2008.

    Science.gov (United States)

    Nicoll, A

    2010-12-01

    To be effective risk prevention work takes place well before pandemics through the three Ps: Planning, Preparedness and Practise. Between 2005 and 2008 the European Centre for Disease Prevention and Control (ECDC) worked with the European Commission (EC) and the WHO Regional Office for Europe (WHO-Euro) to assist European countries in preparing themselves for a future influenza pandemic. All eligible countries in the European Union and European Economic Area participated with energy and commitment. Indicators of preparedness were developed based on WHO planning guidance and these were set within a simple assessment which included a formal country visit. The procedure evolved considerably with field experience. As the complexity of pandemic preparedness was appreciated it changed from being a classical short external assessment to longer national self-assessments with demonstrable impact, especially when self-assessments were published. There were essential supporting activities undertaken including a series of pan-European pandemic preparedness workshops organised by EC, WHO-Euro, ECDC and countries holding the European Union Presidency. The self-assessments highlighted additional work and documentation that was needed by national authorities from the ECDC. This work was undertaken and the document produced. The benefits of the self-assessments were seen in the 2009 pandemic in that EU/EEA countries performed better than some others. A number of the guidance documents were updated to fit the specific features of the pandemic. However the pandemic revealed many weaknesses and brought new challenges for European countries, notably over communication and vaccines, the need to prepare for a variety of scenarios and to factor severity estimates into preparedness, to improve surveillance for severe disease and to deliver seroepidemiology. Any revised self-assessment procedure will need to respond to these challenges.

  11. Anesthesia for radiologic procedures

    International Nuclear Information System (INIS)

    Forestner, J.E.

    1987-01-01

    Anesthetic techniques for neurodiagnostic studies and radiation therapy have been recently reviewed, but anesthetic involvement in thoracic and abdominal radiology has received little attention. Patient reactions to radiologic contrast media may be of concern to the anesthesiologist, who is often responsible for injecting these agents during diagnostic procedures, and thus is included in this discussion. Finally, the difficulties of administering anesthesia for magnetic resonance imaging (MRI) scans are outlined, in an effort to help anesthesiologist to anticipate problems with this new technologic development. Although there are very few indications for the use of general anesthesia for diagnostic radiologic studies in adults, most procedures performed with children, the mentally retarded, or the combative adult require either heavy sedation or general anesthesia. In selecting an anesthetic technique for a specific procedure, both the patient's disease process and the requirements of the radiologist must be carefully balanced

  12. Congruency sequence effects are driven by previous-trial congruency, not previous-trial response conflict

    OpenAIRE

    Weissman, Daniel H.; Carp, Joshua

    2013-01-01

    Congruency effects in distracter interference tasks are often smaller after incongruent trials than after congruent trials. However, the sources of such congruency sequence effects (CSEs) are controversial. The conflict monitoring model of cognitive control links CSEs to the detection and resolution of response conflict. In contrast, competing theories attribute CSEs to attentional or affective processes that vary with previous-trial congruency (incongruent vs. congruent). The present study s...

  13. ADVANCED PROCEDURE FOR THE MONITORING OF SETTLEMENT AND OPEN SPACE DEVELOPMENT ON BASIS OF TOPOGRAPHICAL GEODATA SETS IN THE IOER-MONITOR

    Directory of Open Access Journals (Sweden)

    G. Meinel

    2012-08-01

    Full Text Available Concept, Procedures and Results of the Monitor of settlement and open space development are presented. The monitoring system will describe the state and the development of land use especially in regard to its sustainability for the entire Federal Republic of Germany. To this end, for the first time ever it makes use of topographical geobasis data (digital landscape model of the Authoritative Topographic-Cartographic Information System, short ATKIS. These data allow for a more precise spatial and contentwise description of land use than that of the land register data, which serve as the basis for the official land use statistics. On the basis of the geobasis data an automatic calculation of indicators from the fields of settlement, open space, nature reserves, population, traffic occurs and landscape fragmentation. The indicators are depicted in thematic maps, thus allowing for spatial and chronological comparisons. In addition to administrative spatial units (federal state, region, district, municipality, the indicator values are also presented in scales of various cell widths. For calculating building-based settlement indicators, the patented program SEMENTA® is used, which is based on an automated evaluation of analogue maps.

  14. Effectiveness of disinfection with alcohol 70% (w/v of contaminated surfaces not previously cleaned

    Directory of Open Access Journals (Sweden)

    Maurício Uchikawa Graziano

    Full Text Available OBJECTIVE: To evaluate the disinfectant effectiveness of alcohol 70% (w/v using friction, without previous cleaning, on work surfaces, as a concurrent disinfecting procedure in Health Services. METHOD: An experimental, randomized and single-blinded laboratory study was undertaken. The samples were enamelled surfaces, intentionally contaminated with Serratia marcescens microorganisms ATCC 14756 106 CFU/mL with 10% of human saliva added, and were submitted to the procedure of disinfection WITHOUT previous cleaning. The results were compared to disinfection preceded by cleaning. RESULTS: There was a reduction of six logarithms of the initial microbial population, equal in the groups WITH and WITHOUT previous cleaning (p=0.440 and a residual microbial load ≤ 102 CFU. CONCLUSION: The research demonstrated the acceptability of the practice evaluated, bringing an important response to the area of health, in particular to Nursing, which most undertakes procedures of concurrent cleaning /disinfecting of these work surfaces.

  15. Effectiveness of disinfection with alcohol 70% (w/v of contaminated surfaces not previously cleaned

    Directory of Open Access Journals (Sweden)

    Maurício Uchikawa Graziano

    2013-04-01

    Full Text Available OBJECTIVE: To evaluate the disinfectant effectiveness of alcohol 70% (w/v using friction, without previous cleaning, on work surfaces, as a concurrent disinfecting procedure in Health Services. METHOD: An experimental, randomized and single-blinded laboratory study was undertaken. The samples were enamelled surfaces, intentionally contaminated with Serratia marcescens microorganisms ATCC 14756 106 CFU/mL with 10% of human saliva added, and were submitted to the procedure of disinfection WITHOUT previous cleaning. The results were compared to disinfection preceded by cleaning. RESULTS: There was a reduction of six logarithms of the initial microbial population, equal in the groups WITH and WITHOUT previous cleaning (p=0.440 and a residual microbial load ≤ 102 CFU. CONCLUSION: The research demonstrated the acceptability of the practice evaluated, bringing an important response to the area of health, in particular to Nursing, which most undertakes procedures of concurrent cleaning /disinfecting of these work surfaces.

  16. Effectiveness of disinfection with alcohol 70% (w/v) of contaminated surfaces not previously cleaned

    OpenAIRE

    Graziano, Maurício Uchikawa; Graziano, Kazuko Uchikawa; Pinto, Flávia Morais Gomes; Bruna, Camila Quartim de Moraes; Souza, Rafael Queiroz de; Lascala, Cesar Angelo

    2013-01-01

    OBJECTIVE: To evaluate the disinfectant effectiveness of alcohol 70% (w/v) using friction, without previous cleaning, on work surfaces, as a concurrent disinfecting procedure in Health Services. METHOD: An experimental, randomized and single-blinded laboratory study was undertaken. The samples were enamelled surfaces, intentionally contaminated with Serratia marcescens microorganisms ATCC 14756 106 CFU/mL with 10% of human saliva added, and were submitted to the procedure of disinfection W...

  17. Improvement and Validation of Weld Residual Stress Modelling Procedure

    International Nuclear Information System (INIS)

    Zang, Weilin; Gunnars, Jens; Dong, Pingsha; Hong, Jeong K.

    2009-06-01

    The objective of this work is to identify and evaluate improvements for the residual stress modelling procedure currently used in Sweden. There is a growing demand to eliminate any unnecessary conservatism involved in residual stress assumptions. The study was focused on the development and validation of an improved weld residual stress modelling procedure, by taking advantage of the recent advances in residual stress modelling and stress measurement techniques. The major changes applied in the new weld residual stress modelling procedure are: - Improved procedure for heat source calibration based on use of analytical solutions. - Use of an isotropic hardening model where mixed hardening data is not available. - Use of an annealing model for improved simulation of strain relaxation in re-heated material. The new modelling procedure is demonstrated to capture the main characteristics of the through thickness stress distributions by validation to experimental measurements. Three austenitic stainless steel butt-welds cases are analysed, covering a large range of pipe geometries. From the cases it is evident that there can be large differences between the residual stresses predicted using the new procedure, and the earlier procedure or handbook recommendations. Previously recommended profiles could give misleading fracture assessment results. The stress profiles according to the new procedure agree well with the measured data. If data is available then a mixed hardening model should be used

  18. Use of a scenario-development procedure to identify potentially disruptive scenarios, Greater Confinement Disposal facility, Area 5, Nevada Test Site

    Energy Technology Data Exchange (ETDEWEB)

    Guzowski, R.V. [Science Applications International Corp., San Diego, CA (United States)]|[Sandia National Labs., Albuquerque, NM (United States). Safety and Risk Assessment Dept.

    1994-12-31

    The Greater Confinement Disposal (GCD) facility includes four boreholes that contain transuranic (TRLT) waste. Presence of the TRU waste means that this facility must comply with the US Environmental Protection Agency`s Environmental Radiation Protection Standards for Management and Disposal of Spent Nuclear Fuel, High-Level and Transuranic Waste-Final Rule 40 CFR Part 191. To comply with the Containment Requirements of this rule, all potentially disruptive events and processes, and by implication all potentially disruptive combinations of events and processes (scenarios), must be identified for possible inclusion in performance assessments. Screening of the FEPs identified four events for scenario development: exploratory drilling for natural resources, drilling withdrawal wells, irrigation, and subsidence. Recent environmental-isotope analyses of the vadose zone suggest that radionuclide transport from the boreholes to the water table by infiltration is not a feasible transport mechanism within the time frame of regulatory concern. For this reason, the event of drilling withdrawal wells was merged with exploratory drilling for resources. The descriptions of the remaining three events were modified slightly to aid in estimation of event probabilities and consequence analyses. The three events are: exploratory drilling for resources penetrates a TRU borehole, irrigation occurs at the Radioactive Waste Management Site (RWMS), and subsidence occurs at the RWMS. Use of a logic diagram with these three events resulted in the construction of eight scenarios, including base-case (undisturbed) conditions. Screening these scenarios at this stage of scenario development was beyond the scope of this task. Based on the implementation assumptions, this scenario-development procedure produced a comprehensive set of mutually exclusive scenarios that are reproducible and auditable for use in GCD performance assessments.

  19. Pollutant Assessments Group procedures manual: Volume 2, Technical procedures

    Energy Technology Data Exchange (ETDEWEB)

    1992-03-01

    This is volume 2 of the manuals that describes the technical procedures currently in use by the Pollution Assessments Group. This manual incorporates new developments in hazardous waste assessment technology and administrative policy. Descriptions of the equipment, procedures and operations of such things as radiation detection, soil sampling, radionuclide monitoring, and equipment decontamination are included in this manual. (MB)

  20. Electronic Procedures for Medical Operations

    Science.gov (United States)

    2015-01-01

    Electronic procedures are replacing text-based documents for recording the steps in performing medical operations aboard the International Space Station. S&K Aerospace, LLC, has developed a content-based electronic system-based on the Extensible Markup Language (XML) standard-that separates text from formatting standards and tags items contained in procedures so they can be recognized by other electronic systems. For example, to change a standard format, electronic procedures are changed in a single batch process, and the entire body of procedures will have the new format. Procedures can be quickly searched to determine which are affected by software and hardware changes. Similarly, procedures are easily shared with other electronic systems. The system also enables real-time data capture and automatic bookmarking of current procedure steps. In Phase II of the project, S&K Aerospace developed a Procedure Representation Language (PRL) and tools to support the creation and maintenance of electronic procedures for medical operations. The goal is to develop these tools in such a way that new advances can be inserted easily, leading to an eventual medical decision support system.

  1. Surgical treatment of breast cancer in previously augmented patients.

    Science.gov (United States)

    Karanas, Yvonne L; Leong, Darren S; Da Lio, Andrew; Waldron, Kathleen; Watson, James P; Chang, Helena; Shaw, William W

    2003-03-01

    The incidence of breast cancer is increasing each year. Concomitantly, cosmetic breast augmentation has become the second most often performed cosmetic surgical procedure. As the augmented patient population ages, an increasing number of breast cancer cases among previously augmented women can be anticipated. The surgical treatment of these patients is controversial, with several questions remaining unanswered. Is breast conservation therapy feasible in this patient population and can these patients retain their implants? A retrospective review of all breast cancer patients with a history of previous augmentation mammaplasty who were treated at the Revlon/UCLA Breast Center between 1991 and 2001 was performed. During the study period, 58 patients were treated. Thirty patients (52 percent) were treated with a modified radical mastectomy with implant removal. Twenty-eight patients (48 percent) underwent breast conservation therapy, which consisted of lumpectomy, axillary lymph node dissection, and radiotherapy. Twenty-two of the patients who underwent breast conservation therapy initially retained their implants. Eleven of those 22 patients (50 percent) ultimately required completion mastectomies with implant removal because of implant complications (two patients), local recurrences (five patients), or the inability to obtain negative margins (four patients). Nine additional patients experienced complications resulting from their implants, including contracture, erosion, pain, and rupture. The data illustrate that breast conservation therapy with maintenance of the implant is not ideal for the majority of augmented patients. Breast conservation therapy with explantation and mastopexy might be appropriate for rare patients with large volumes of native breast tissue. Mastectomy with immediate reconstruction might be a more suitable choice for these patients.

  2. A Guide for Developing Standard Operating Job Procedures for the Tertiary Chemical Treatment - Lime Precipitation Process Wastewater Treatment Facility. SOJP No. 6.

    Science.gov (United States)

    Petrasek, Al, Jr.

    This guide describes the standard operating job procedures for the tertiary chemical treatment - lime precipitation process of wastewater treatment plants. Step-by-step instructions are given for pre-start up, start-up, continuous operation, and shut-down procedures. In addition, some theoretical material is presented along with some relevant…

  3. Construction of a Logo Environment Supporting the Development of Procedural Skills=Elaboration D'Un Environnement Logo Favorable Au Developpement D'Habiletes En Manipulation Procedurale.

    Science.gov (United States)

    Lemerise, Tamara; And Others

    1992-01-01

    Learning environment that facilitated the acquisition and expression of procedural skills in LOGO was set up for children in the 10- to 12-year range. Ten participants were placed in a series of situations that required them to manipulate programing procedures in LOGO. Analysis of children's behavior revealed their competence in manipulating…

  4. Series expansion of the modified Einstein Procedure

    Science.gov (United States)

    Seema Chandrakant Shah-Fairbank

    2009-01-01

    This study examines calculating total sediment discharge based on the Modified Einstein Procedure (MEP). A new procedure based on the Series Expansion of the Modified Einstein Procedure (SEMEP) has been developed. This procedure contains four main modifications to MEP. First, SEMEP solves the Einstein integrals quickly and accurately based on a series expansion. Next,...

  5. Genomic variability in Potato virus M and the development of RT-PCR and RFLP procedures for the detection of this virus in seed potatoes

    Directory of Open Access Journals (Sweden)

    Nie Jingbai

    2010-02-01

    Full Text Available Abstract Potato virus M (PVM, Carlavirus is considered to be one of the most common potato viruses distributed worldwide. Sequences of the coat protein (CP gene of several Canadian PVM isolates were determined. Phylogenetic analysis indicated that all known PVM isolates fell into two distinct groups and the isolates from Canada and the US clustered in the same group. The Canadian PVM isolates could be further divided into two sub-groups. Two molecular procedures, reverse transcription - polymerase chain reaction (RT-PCR and restriction fragment length polymorphism (RFLP were developed in this study for the detection and identification of PVM in potato tubers. RT-PCR was highly specific and only amplified PVM RNA from potato samples. PVM RNAs were easily detected in composite samples of 400 to 800 potato leaves or 200 to 400 dormant tubers. Restriction analysis of PCR amplicons with MscI was a simple method for the confirmation of PCR tests. Thus, RT-PCR followed by RFLP analysis may be a useful approach for screening potato samples on a large scale for the presence of PVM.

  6. Algorithm for video summarization of bronchoscopy procedures.

    Science.gov (United States)

    Leszczuk, Mikołaj I; Duplaga, Mariusz

    2011-12-20

    The duration of bronchoscopy examinations varies considerably depending on the diagnostic and therapeutic procedures used. It can last more than 20 minutes if a complex diagnostic work-up is included. With wide access to videobronchoscopy, the whole procedure can be recorded as a video sequence. Common practice relies on an active attitude of the bronchoscopist who initiates the recording process and usually chooses to archive only selected views and sequences. However, it may be important to record the full bronchoscopy procedure as documentation when liability issues are at stake. Furthermore, an automatic recording of the whole procedure enables the bronchoscopist to focus solely on the performed procedures. Video recordings registered during bronchoscopies include a considerable number of frames of poor quality due to blurry or unfocused images. It seems that such frames are unavoidable due to the relatively tight endobronchial space, rapid movements of the respiratory tract due to breathing or coughing, and secretions which occur commonly in the bronchi, especially in patients suffering from pulmonary disorders. The use of recorded bronchoscopy video sequences for diagnostic, reference and educational purposes could be considerably extended with efficient, flexible summarization algorithms. Thus, the authors developed a prototype system to create shortcuts (called summaries or abstracts) of bronchoscopy video recordings. Such a system, based on models described in previously published papers, employs image analysis methods to exclude frames or sequences of limited diagnostic or education value. The algorithm for the selection or exclusion of specific frames or shots from video sequences recorded during bronchoscopy procedures is based on several criteria, including automatic detection of "non-informative", frames showing the branching of the airways and frames including pathological lesions. The paper focuses on the challenge of generating summaries of

  7. Algorithm for Video Summarization of Bronchoscopy Procedures

    Directory of Open Access Journals (Sweden)

    Leszczuk Mikołaj I

    2011-12-01

    Full Text Available Abstract Background The duration of bronchoscopy examinations varies considerably depending on the diagnostic and therapeutic procedures used. It can last more than 20 minutes if a complex diagnostic work-up is included. With wide access to videobronchoscopy, the whole procedure can be recorded as a video sequence. Common practice relies on an active attitude of the bronchoscopist who initiates the recording process and usually chooses to archive only selected views and sequences. However, it may be important to record the full bronchoscopy procedure as documentation when liability issues are at stake. Furthermore, an automatic recording of the whole procedure enables the bronchoscopist to focus solely on the performed procedures. Video recordings registered during bronchoscopies include a considerable number of frames of poor quality due to blurry or unfocused images. It seems that such frames are unavoidable due to the relatively tight endobronchial space, rapid movements of the respiratory tract due to breathing or coughing, and secretions which occur commonly in the bronchi, especially in patients suffering from pulmonary disorders. Methods The use of recorded bronchoscopy video sequences for diagnostic, reference and educational purposes could be considerably extended with efficient, flexible summarization algorithms. Thus, the authors developed a prototype system to create shortcuts (called summaries or abstracts of bronchoscopy video recordings. Such a system, based on models described in previously published papers, employs image analysis methods to exclude frames or sequences of limited diagnostic or education value. Results The algorithm for the selection or exclusion of specific frames or shots from video sequences recorded during bronchoscopy procedures is based on several criteria, including automatic detection of "non-informative", frames showing the branching of the airways and frames including pathological lesions. Conclusions

  8. Martius procedure revisited for urethrovaginal fistula

    Directory of Open Access Journals (Sweden)

    N P Rangnekar

    2000-01-01

    Full Text Available Background: Urethrovaginal fistula is a dreadful com-plication of obstetric trauma due to prolonged labour or obstetric intervention commonly seen in developing coun-tries. Due to prolonged ischaemic changes, the fistula is resistant to healing. The strategic location of the fistula leads to postoperative impairment of continence mecha-nism. Anatomical repair was previously the commonest mode of surgical management, but was associated with a miserable cumulative cure rate ranging from 16-60%. Hence we tried to study the efficacy of Martius procedure in the management of urethrovaginal fistula. Material and Methods: We studied the outcome of 12 urethrovaginal fistulae, all caused by obstetric trauma, treated surgically with Martius procedure in 8 and with anatomical repair in 4, retrospectively. 9 patients had re-current fistulae while I patient had multiple fistulae. Pa-tients were followed up for the period ranging from 6 months to 4′/2 years for fistula healing, continence and postoperative complications like dvspareunia. Results: Cumulative cure rate ofMartius procedure was 87.5% with no postoperative stress incontinence, while fistula healing rate of anatomical repair was only 25% (I patient out of 4 which was also complicated by Intrin-sic Sphincter Deficiency (ISD. In case of recurrent fistu-lae the success rate of anatomical repair was 0% compared to 83.33% with Martius procedure. Conclusions: Martius procedure has shown much bet-ter overall cure rate compared to anatomical repair be-cause - a it provides better reinforcement to urethral suture line, b it provides better blood supply and lymph drainage to the ischaemic fistulous area, c provides sur-face for epithelialization and, d helps to maintain conti-nence. Hence we recommend Martius procedure as a surgical modality for the treatment of urethrovaginal fis-tula.

  9. Endovascular thrombectomy and post-procedural headache.

    Science.gov (United States)

    Khan, Sabrina; Amin, Faisal Mohammad; Holtmannspötter, Markus; Hansen, Klaus; Florescu, Anna Maria; Fakhril-Din, Zainab; Petersen, Julie Falkenberg; Ghanizada, Hashmat; Ayata, Cenk; Gaist, David; Ashina, Messoud

    2017-12-01

    We investigated the prevalence of post-procedural headache in patients who have undergone thrombectomy for ischemic stroke, and correlated history of migraine with risk of peri-procedural complications. A total of 314 patients underwent thrombectomy at the Danish National Hospital from January 2012 to December 2014. Eligible subjects were phone-interviewed using a purpose-developed semi-structured questionnaire according to the International Classification of Headache Disorders 3, beta version criteria. Among 96 eligible subjects, there was a significant decrease in migraine (p = 0.022) within the first 3 months after EVT compared to 1 year before treatment, which was further evident at interview time (on average 1.6 years after EVT, p = 0.013). A minority of patients experienced headaches for the first time within 3 months of their EVT (migraine 2, TTH 9), which persisted at interview time for subjects with migraine. Out of 12 subjects with peri-procedural complications, 2 had a history of migraine with aura. Thrombectomy leads to a significant decrease in previously known migraine, and new onset of headache in a small subset of patients. A history of migraine does not appear to predispose to peri-procedural complications.

  10. Development and Psychometric Validation of the FACE-Q Skin, Lips, and Facial Rhytids Appearance Scales and Adverse Effects Checklists for Cosmetic Procedures.

    Science.gov (United States)

    Klassen, Anne F; Cano, Stefan J; Schwitzer, Jonathan A; Baker, Stephen B; Carruthers, Alastair; Carruthers, Jean; Chapas, Anne; Pusic, Andrea L

    2016-04-01

    Patient-reported outcomes data are needed to determine the efficacy of cosmetic procedures. To describe the development and psychometric evaluation of 8 appearance scales and 2 adverse effect checklists for use in minimally invasive cosmetic procedures. We performed a psychometric study to select the most clinically sensitive items for inclusion in item-reduced scales and to examine reliability and validity with patients. Recruitment of the sample for this study took place from June 6, 2010, through July 28, 2014. Data analysis was performed from December 11, 2014, to December 22, 2015. Pretreatment and posttreatment patients 18 years and older who were consulting for any type of facial aesthetic treatment were studied. Patients were from plastic surgery and dermatology outpatient clinics in the United States and Canada (field-test sample) and a clinical trial of a minimally invasive lip treatment in the United Kingdom and France (clinical trial sample). The FACE-Q scales that measure appearance of the skin, lips, and facial rhytids (ie, overall, forehead, glabella, lateral periorbital area, lips, and marionette lines), with scores ranging from 0 (lowest) to 100 (highest), and the FACE-Q adverse effects checklists for problems after skin and lip treatment. Of 783 patients recruited, 503 field-test patients (response rate, 90%) and 280 clinical trial participants were studied. The mean (SD) age of the patients was 47.4 (14.0) years in the field-test sample and 47.7 (12.3) years in the clinical trial sample. Most of the patients were female (429 [85.3%] in the field-test sample and 274 [97.9%] in the clinical trial sample). Rasch Measurement Theory analyses led to the refinement of 8 appearance scales with 66 total items. All FACE-Q scale items had ordered thresholds and acceptable item fit. Reliability, measured with the Personal Separation Index (range, 0.88-0.95) and Cronbach α (range, 0.93-0.98), was high. Lower scores for appearance scales that measured the

  11. Development of a digital image correlation procedure adapted for kinematic measurements in polycrystals: application to the identification of crystal plasticity laws parameters

    International Nuclear Information System (INIS)

    Guery, Adrien

    2014-01-01

    A digital image correlation procedure adapted to kinematic measurements in polycrystals has been developed in this work to identify parameters of crystal plasticity laws. 2D kinematic measurements are performed on the surface of 316LN austenitic steel polycrystals from a sequence of images acquired using a Scanning Electron Microscope (SEM) during in-situ tensile tests for various mean grain sizes. To enable digital image correlation, a speckle adapted to the microscopic scale is deposited onto the specimen surface by a microlithography process. Spatial distortions resulting from both patterning and SEM imaging techniques are quantified. The knowledge of the microstructure at the surface by electron backscattered diffraction allows for kinematic measurements to be performed using an unstructured finite element mesh taking as support the grain or twin boundaries. This same mesh is then used for the simulation of each tensile test on the experimental microstructure with the measured nodal displacements prescribed as boundary conditions with their time evolution. Two local crystal plasticity laws are considered to simulate the observed strain heterogeneities, namely, the Meric-Cailletaud model and the DD-CFC law developed at EDF R and D. Comparisons between measurements and simulations are performed in terms of displacements, strains but also activated slip systems. Last, an inverse identification method is proposed for the identification of the sought constitutive parameters based on both the local displacement fields and the material homogenized behavior. The parameters associated with isotropic hardening of Meric-Cailletaud law are thus identified for various mean grain sizes. It is also shown that some of the interaction parameters of slip systems can be estimated. (author)

  12. Cutaneous protothecosis in a patient with previously undiagnosed HIV infection.

    Science.gov (United States)

    Fong, Kenneth; Tee, Shang-Ian; Ho, Madeline S L; Pan, Jiun Yit

    2015-08-01

    Protothecosis is an uncommon condition resulting from infection by achlorophyllous algae of the Prototheca species. Immunocompromised individuals are generally most susceptible to protothecal infection and tend to develop severe and disseminated disease. However, the association between protothecosis and HIV-induced immunosuppression is not clear, with only a handful of cases having been described to date. Here we report a case of cutaneous protothecosis in a Chinese man with previously undiagnosed HIV infection that responded well to oral itraconazole. © 2014 The Australasian College of Dermatologists.

  13. Considerations for the selection of an applicable energy efficiency test procedure for electric motors in Malaysia: Lessons for other developing countries

    International Nuclear Information System (INIS)

    Yanti, P.A.A.; Mahlia, T.M.I.

    2009-01-01

    Electric motors are a major energy-consuming appliance in the industrial sector. According to a survey, electric motors account for more than 70% of the total growth from 1991 to 2004 in electricity consumption in this sector in Malaysia. To reduce electricity consumption, Malaysia should consider resetting the minimum energy efficiency standards for electric motors sometime in the coming year. The first step towards adopting energy efficiency standards is the creation of a procedure for testing and rating equipment. An energy test procedure is the technical foundation for all energy efficiency standards, energy labels and other related programs. The test conditions in the test procedure must represent the conditions of the country. This paper presents the process for the selection of an energy test procedure for electric motors in Malaysia based on the country's conditions and requirements. The adoption of test procedures for electric motors internationally by several countries is also discussed in this paper. Even though the paper only discusses the test procedure for electric motors in Malaysia, the methods can be directly applied in other countries without major modifications.

  14. Repeat coronary angiography with previously normal arteries: a futile exercise?

    Science.gov (United States)

    Rowe, Rebecca; Parviz, Yasir; Iqbal, Javaid; Heppenstall, James; Teare, Dawn; Gunn, Julian

    2015-02-15

    Up to 20% of coronary angiograms reveal normal arteries. How long they stay normal is poorly understood. This study investigated the fate of normal coronary arteries and determined the rate of development of coronary artery disease. We interrogated the angiographic archive of the South Yorkshire Cardiothoracic Centre between 2004 and 2013 to identify patients with truly normal coronary arteries who underwent repeat coronary angiography more than 1 year later. Follow up angiograms were scored for the severity and extent of CAD (graded per segment as 0%, 1-50%, >50%). Risk factors for the development of coronary artery disease were documented. Univariate predictors of disease development were identified and entered into a logistic regression model to identify independent predictors. Out of over 25,000 angiographic procedures in the archives we found 6068 patients reported to have normal coronary arteries. Of these, 162 patients had also undergone subsequent repeat coronary angiography. Of these, 97 had truly normal (smooth) coronary arteries at baseline and had undergone repeat angiography >1 year later. At a median 51 months, 87 continued to have normal arteries, and all the remaining 10 had mild disease only (average 37% stenosis in an average 1.2 segments). No patients developed any significant (>50% stenosis) disease. Advanced age, time between angiograms, and smoking status were identified as independent predictors of development of CAD. Truly normal coronary arteries do not progress to significant disease within a time frame of 4 years. Repeat coronary angiography within that period is probably not indicated. © 2014 Wiley Periodicals, Inc.

  15. Serratia liquefaciens Infection of a Previously Excluded Popliteal Artery Aneurysm

    Directory of Open Access Journals (Sweden)

    A. Coelho

    Full Text Available : Introduction: Popliteal artery aneurysms (PAAs are rare in the general population, but they account for nearly 70% of peripheral arterial aneurysms. There are several possible surgical approaches including exclusion of the aneurysm and bypass grafting, or endoaneurysmorrhaphy and interposition of a prosthetic conduit. The outcomes following the first approach are favorable, but persistent blood flow in the aneurysm sac has been documented in up to one third of patients in the early post-operative setting. Complications from incompletely excluded aneurysms include aneurysm enlargement, local compression symptoms, and sac rupture. Notably infection of a previously excluded and bypassed PAA is rare. This is the third reported case of PAA infection after exclusion and bypass grafting and the first due to Serratia liquefaciens. Methods: Relevant medical data were collected from the hospital database. Results: This case report describes a 54 year old male patient, diagnosed with acute limb ischaemia due to a thrombosed PAA, submitted to emergency surgery with exclusion and venous bypass. A below the knee amputation was necessary 3 months later. Patient follow-up was lost until 7 years following surgical repair, when he was diagnosed with aneurysm sac infection with skin fistulisation. He had recently been diagnosed with alcoholic hepatic cirrhosis Child–Pugh Class B. The patient was successfully treated by aneurysm resection, soft tissue debridement and systemic antibiotics. Conclusion: PAA infection is a rare complication after exclusion and bypass procedures but should be considered in any patient with evidence of local or systemic infection. When a PAA infection is diagnosed, aneurysmectomy, local debridement, and intravenous antibiotic therapy are recommended. The “gold standard” method of PAA repair remains controversial. PAA excision or endoaneurysmorrhaphy avoids complications from incompletely excluded aneurysms, but is associated with

  16. The Groningen ART cohort study: Does ovarian hyperstimulation, the in vitro procedure or a combination of both influence cognitive and behavioural development of 4-year-old IVF-offspring?

    NARCIS (Netherlands)

    Schendelaar, P.; La Bastide-Van Gemert, S.; Heineman, M.J.; Middelburg, K.J.; Seggers, J.; Van Den Heuvel, E.R.; Hadders-Algra, M.

    2014-01-01

    Study question: Evaluating the effects and underlying causal relationships of ovarian hyperstimulation, the in vitro procedure and the combination of both on cognitive and behavioural development in 4-year-olds. Summary answer: Our preliminary results suggest that ovarian hyperstimulation, the in

  17. PACS policies and procedures.

    Science.gov (United States)

    Knepper, Daniel

    2007-01-01

    Documentation of policies and procedures are critical for the proper operation and management of a picture archival and communication system (PACS). Policies, procedures, and site specific documentation may be organized in several categories. Through the use of broad categories one can easily begin to break down the specific areas which require attention and prioritize them as necessary. One way to categorize them is: administration, maintenance, support, architecture and integration, and disaster recovery/business continuity. One area that requires a great deal of focus and discipline is a policy for "change management." It is essential to have a policy in place for making changes to the information system. This would include not only changes to the system such as software upgrades, but changes to workflows such as how images are being distributed, compression settings, network settings, monitor settings, locations of workstations, integration, and disaster recovery/ business continuity. Modifying existing information technology (IT) policies and using published resources can largely simplify the development of organization specific policies and procedures.

  18. Development of a new procedure for the determination of captopril in pharmaceutical formulations employing chemiluminescence and a multicommuted flow analysis approach.

    Science.gov (United States)

    Lima, Manoel J A; Fernandes, Ridvan N; Tanaka, Auro A; Reis, Boaventura F

    2016-02-01

    This paper describes a new technique for the determination of captopril in pharmaceutical formulations, implemented by employing multicommuted flow analysis. The analytical procedure was based on the reaction between hypochlorite and captopril. The remaining hypochlorite oxidized luminol that generated electromagnetic radiation detected using a homemade luminometer. To the best of our knowledge, this is the first time that this reaction has been exploited for the determination of captopril in pharmaceutical products, offering a clean analytical procedure with minimal reagent usage. The effectiveness of the proposed procedure was confirmed by analyzing a set of pharmaceutical formulations. Application of the paired t-test showed that there was no significant difference between the data sets at a 95% confidence level. The useful features of the new analytical procedure included a linear response for captopril concentrations in the range 20.0-150.0 µmol/L (r = 0.997), a limit of detection (3σ) of 2.0 µmol/L, a sample throughput of 164 determinations per hour, reagent consumption of 9 µg luminol and 42 µg hypochlorite per determination and generation of 0.63 mL of waste. A relative standard deviation of 1% (n = 6) for a standard solution containing 80 µmol/L captopril was also obtained. Copyright © 2015 John Wiley & Sons, Ltd.

  19. Apollo experience report: The development of design-loads criteria, methods, and operational procedures for prelaunch, lift-off, and midboost conditions

    Science.gov (United States)

    Mackey, A. C.; Schwartz, R. D.

    1973-01-01

    The prelaunch, lift-off, and midboost conditions that are important to the design of spacecraft are described. Original Apollo design concepts that were deficient in realistic and accurate analysis of spacecraft structural loads in a wind environment also are included. Important improvements in design criteria, mathematical models, wind-monitoring procedures, and loads analyses are discussed. Recommendations for future programs are presented.

  20. Integrating Mobile Phones into Science Teaching to Help Students Develop a Procedure to Evaluate the Corrosion Rate of Iron in Simulated Seawater

    Science.gov (United States)

    Moraes, Edgar P.; Confessor, Mario R.; Gasparotto, Luiz H. S.

    2015-01-01

    This article proposes an indirect method to evaluate the corrosion rate of iron nail in simulated seawater. The official procedure is based on the direct measurement of the specimen's weight loss over time; however, a highly precise scale is required and such equipment may not be easily available. On the other hand, mobile phones equipped with…

  1. High-Grade Leiomyosarcoma Arising in a Previously Replanted Limb

    Directory of Open Access Journals (Sweden)

    Tiffany J. Pan

    2015-01-01

    Full Text Available Sarcoma development has been associated with genetics, irradiation, viral infections, and immunodeficiency. Reports of sarcomas arising in the setting of prior trauma, as in burn scars or fracture sites, are rare. We report a case of a leiomyosarcoma arising in an arm that had previously been replanted at the level of the elbow joint following traumatic amputation when the patient was eight years old. He presented twenty-four years later with a 10.8 cm mass in the replanted arm located on the volar forearm. The tumor was completely resected and pathology examination showed a high-grade, subfascial spindle cell sarcoma diagnosed as a grade 3 leiomyosarcoma with stage pT2bNxMx. The patient underwent treatment with brachytherapy, reconstruction with a free flap, and subsequently chemotherapy. To the best of our knowledge, this is the first case report of leiomyosarcoma developing in a replanted extremity. Development of leiomyosarcoma in this case could be related to revascularization, scar formation, or chronic injury after replantation. The patient remains healthy without signs of recurrence at three-year follow-up.

  2. MITG test procedure and results

    International Nuclear Information System (INIS)

    Eck, M.E.; Mukunda, M.

    1983-01-01

    Elements and modules for Radioisotope Thermoelectric Generator have been performance tested since the inception of the RTG program. These test articles seldom resembled flight hardware and often lacked adequate diagnostic instrumentation. Because of this, performance problems were not identified in the early stage of program development. The lack of test data in an unexpected area often hampered the development of a problem solution. A procedure for conducting the MITG Test was developed in an effort to obtain data in a systematic, unambiguous manner. This procedure required the development of extensive data acquisition software and test automation. The development of a facility to implement the test procedure, the facility hardware and software requirements, and the results of the MITG testing are the subject of this paper

  3. Uranium hexafluoride: Handling procedures and container descriptions

    International Nuclear Information System (INIS)

    1987-09-01

    The US Department of Energy (DOE) guidelines for packaging, measuring, and transferring uranium hexafluoride (UF 6 ) have been undergoing continual review and revision for several years to keep them in phase with developing agreements for the supply of enriched uranium. Initially, K-1323 ''A Brief Guide to UF 6 Handling,'' was issued in 1957. This was superceded by ORO-651, first issued in 1966, and reissued in 1967 to make editorial changes and to provide minor revisions in procedural information. In 1968 and 1972, Revisions 2 and 3, respectively, were issued as part of the continuing effort to present updated information. Revision 4 issued in 1977 included revisions to UF 6 cylinders, valves, and methods to use. Revision 5 adds information dealing with pigtails, overfilled cylinders, definitions and handling precautions, and cylinder heel reduction procedures. Weighing standards previously presented in ORO-671, Vol. 1 (Procedures for Handling and Analysis of UF 6 ) have also been included. This revision, therefore, supercedes ORO-671-1 as well as all prior issues of this report. These guidelines will normally apply in all transactions involving receipt or shipment of UF 6 by DOE, unless stipulated otherwise by contracts or agreements with DOE or by notices published in the Federal Register. Any questions or requests for additional information on the subject matter covered herein should be directed to the United States Department of Energy, P.O. Box E, Oak Ridge, Tennessee 37831, Attention: Director, Uranium Enrichment Operations Division. 33 figs., 12 tabs

  4. Working, declarative and procedural memory in specific language impairment

    Science.gov (United States)

    Lum, Jarrad A.G.; Conti-Ramsden, Gina; Page, Debra; Ullman, Michael T.

    2012-01-01

    According to the Procedural Deficit Hypothesis (PDH), abnormalities of brain structures underlying procedural memory largely explain the language deficits in children with specific language impairment (SLI). These abnormalities are posited to result in core deficits of procedural memory, which in turn explain the grammar problems in the disorder. The abnormalities are also likely to lead to problems with other, non-procedural functions, such as working memory, that rely at least partly on the affected brain structures. In contrast, declarative memory is expected to remain largely intact, and should play an important compensatory role for grammar. These claims were tested by examining measures of working, declarative and procedural memory in 51 children with SLI and 51 matched typically-developing (TD) children (mean age 10). Working memory was assessed with the Working Memory Test Battery for Children, declarative memory with the Children’s Memory Scale, and procedural memory with a visuo-spatial Serial Reaction Time task. As compared to the TD children, the children with SLI were impaired at procedural memory, even when holding working memory constant. In contrast, they were spared at declarative memory for visual information, and at declarative memory in the verbal domain after controlling for working memory and language. Visuo-spatial short-term memory was intact, whereas verbal working memory was impaired, even when language deficits were held constant. Correlation analyses showed neither visuo-spatial nor verbal working memory was associated with either lexical or grammatical abilities in either the SLI or TD children. Declarative memory correlated with lexical abilities in both groups of children. Finally, grammatical abilities were associated with procedural memory in the TD children, but with declarative memory in the children with SLI. These findings replicate and extend previous studies of working, declarative and procedural memory in SLI. Overall, we

  5. Specified assurance level sampling procedure

    International Nuclear Information System (INIS)

    Willner, O.

    1980-11-01

    In the nuclear industry design specifications for certain quality characteristics require that the final product be inspected by a sampling plan which can demonstrate product conformance to stated assurance levels. The Specified Assurance Level (SAL) Sampling Procedure has been developed to permit the direct selection of attribute sampling plans which can meet commonly used assurance levels. The SAL procedure contains sampling plans which yield the minimum sample size at stated assurance levels. The SAL procedure also provides sampling plans with acceptance numbers ranging from 0 to 10, thus, making available to the user a wide choice of plans all designed to comply with a stated assurance level

  6. 22 CFR 40.91 - Certain aliens previously removed.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Certain aliens previously removed. 40.91... IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Aliens Previously Removed § 40.91 Certain aliens previously removed. (a) 5-year bar. An alien who has been found inadmissible, whether as a result...

  7. Numerical comparison between different strength after impact test procedures

    Directory of Open Access Journals (Sweden)

    Klaus M.

    2010-06-01

    Full Text Available Different procedures are established to investigate the residual properties of sandwich panels after impact damage. Two used procedures for the testing of this properties are compression after impact (CAI and 4-point bending. In this paper a numerical procedure is presented for a first prediction of the behaviour of pre-damaged sandwich specimens under different boundary conditions (or testing procedures. A sequence of impact experiments using a drop tower is performed to assess the damage tolerance of sandwich panels with aramid paper foldcores and CFRP skins. The tested impact energy range allowed to investigate a variety of damage scenarios from barely visible damages (BVID to fibre fractures in all plies of the impacted face sheet. Additionally 4-point bending tests are performed with the panels previously damaged by impact loadings to assess the residual bending strength of these samples. The developed numerical procedure is used to reproduce these experiments (the impact as well as the 4-point bending tests. Also the same procedure is employed in an attempt to predict the behaviour of samples with the same build-up in simulated compression after impact tests.

  8. Use of scripts and script-fading procedures and activity schedules to develop spontaneous social interaction in a three-year-old girl with autism

    Directory of Open Access Journals (Sweden)

    Anna Budzińska

    2014-05-01

    Full Text Available Autism entails serious deficiencies in communication and social behaviors. Individuals with autism, even those who have received intensive language intervention, are often viewed as lacking spontaneous language. In addition, some children with autism lack the ability of spontaneously seeking to share enjoyment, interests, or achievements with other people (e.g., a lack of showing, bringing, or pointing out objects of interest to other people. The aim of the study was to use ABA teaching techniques such as script and script fading procedure and activity schedule to teach three-year-old girl with autism spontaneous social interaction and shape joint attention skills. The result shows that ABA techniques were very effective in teaching many verbal skills such as answering questions, making requests, initiating conversation and asking question. Comparison made after implemented teaching procedure shows her initiating of joint attention skill (IJA is at the appropriate level for her age.

  9. Determining root correspondence between previously and newly detected objects

    Science.gov (United States)

    Paglieroni, David W.; Beer, N Reginald

    2014-06-17

    A system that applies attribute and topology based change detection to networks of objects that were detected on previous scans of a structure, roadway, or area of interest. The attributes capture properties or characteristics of the previously detected objects, such as location, time of detection, size, elongation, orientation, etc. The topology of the network of previously detected objects is maintained in a constellation database that stores attributes of previously detected objects and implicitly captures the geometrical structure of the network. A change detection system detects change by comparing the attributes and topology of new objects detected on the latest scan to the constellation database of previously detected objects.

  10. 10 CFR 26.157 - Procedures.

    Science.gov (United States)

    2010-01-01

    ...) Written chain-of-custody procedures must describe the methods to be used to maintain control and...) Calibration procedures; (4) Derivation of results; (5) Linearity of methods; (6) Sensitivity of the methods... laboratories shall develop, implement, and maintain written procedures for instrument setup and normal...

  11. Clinical Risk Factors Affecting Procedure-Related Major Neurological Complications in Unruptured Intracranial Aneurysms.

    Science.gov (United States)

    Jang, E-Wook; Kim, Yong Bae; Chung, Joonho; Suh, Sang Hyun; Hong, Chang-Ki; Joo, Jin-Yang

    2015-07-01

    The operative risk and natural history rupture risk for the treatment of unruptured intracranial aneurysms (UIAs) should be evaluated. The purpose of this study was to report our experience with treating UIAs and to outline clinical risk factors associated with procedure-related major neurological complications. We treated 1158 UIAs in 998 patients over the last 14 years. All patients underwent operation performed by a single microvascular surgeon and two interventionists at a single institution. Patient factors, aneurysm factors, and clinical outcomes were analyzed in relation to procedure-related complications. The total complication rate was 22 (2.2%) out of 998 patients. Among them, complications developed in 14 (2.3%) out of 612 patients who underwent microsurgery and in 8 (2.1%) out of 386 patients who underwent endovascular procedures. One patient died due to intraoperative rupture during an endovascular procedure. The procedure-related complication was highly correlated with age (p=0.004), hypertension (p=0.002), and history of ischemic stroke (p<0.001) in univariate analysis. The multivariate analysis revealed previous history of ischemic stroke (p=0.001) to be strongly correlated with procedure-related complications. A history of ischemic stroke was strongly correlated with procedure-related major neurological complications when treating UIAs. Accordingly, patients with UIAs who have a previous history of ischemic stroke might be at risk of procedure-related major neurological complications.

  12. Integrated System Validation Usability Questionnaire: Computerized Procedures

    International Nuclear Information System (INIS)

    Garcés, Ma. I.; Torralba, B.

    2015-01-01

    The Research and Development (R&D) project on “Theoretical and Methodological Approaches to Integrated System Validation of Control Rooms, 2014-2015”, in which the research activities described in this report are framed, has two main objectives: to develop the items for an usability methodology conceived as a part of the measurement framework for performance-based control room evaluation that the OECD Halden Reactor Project will test in the experiments planned for 2015; and the statistical analysis of the data generated in the experimental activities of the Halden Man-Machine Laboratory (HAMMLAB) facility, with previous usability questionnaires, in 2010 and 2011. In this report, the procedure designed to meet the first goal of the project is described, in particular, the process followed to identify the items related to operating procedures, both computer and paper-based, one of the elements to be included in the usability questionnaire. Three phases are performed, in the first one, the approaches developed by the United States Nuclear Regulatory Commission, NRC, are reviewed, the models used by the nuclear industry and their technical support organizations, mainly, the Electric Power Research Institute, EPRI, are analyzed, and scientist advances are also explored. In the remaining stages, general and specific guidelines for computerized and paper-based procedures are compared and criteria for the preliminary selection of the items that should be incorporated into the usability questionnaire are defined. This proposal will be reviewed and adapted by the Halden Reactor Project to the design of the specific experiments performed in HAMLAB.

  13. Development of analytical procedures for determination of total chromium by quadrupole ICP-MS and high-resolution ICP-MS, and hexavalent chromium by HPLC-ICP-MS, in different materials used in the automotive industry.

    Science.gov (United States)

    Séby, F; Gagean, M; Garraud, H; Castetbon, A; Donard, O F X

    2003-10-01

    A European directive was recently adopted limiting the use of hazardous substances such as Pb, Hg, Cd, and Cr(VI) in vehicle manufacturing. From July 2003 a maximum of 2 g Cr(VI) will be authorised per vehicle in corrosion-preventing coatings of key components. As no standardised procedures are available to check if produced vehicles are in agreement with this directive, the objective of this work was to develop analytical procedures for total chromium and Cr(VI) determination in these materials. The first step of this study was to optimise digestion procedures for total chromium determination in plastic and metallic materials by inductively coupled plasma mass spectrometry (ICP-MS). High resolution (HR) ICP-MS was used to examine the influence of polyatomic interferences on the detection of the (52)Cr(+) and (53)Cr(+) isotopes. If there was strong interference with m/ z 52 for plastic materials, it was possible to use quadrupole ICP-MS for m/ z 53 if digestions were performed with HNO(3)+H(2)O(2). This mixture was also necessary for digestion of chromium from metallic materials. Extraction procedures in alkaline medium (NH(4)(+)/NH(3) buffer solution at pH 8.9) assisted by sonication were developed for determining Cr(VI) in four different corrosion-preventing coatings by HPLC-ICP-MS. After optimisation and validation with the only solid reference material certified for its Cr(VI) content (BCR 545; welding dusts), the efficiency of this extraction procedure for screw coatings was compared with that described in the EN ISO 3613 standard generally used in routine laboratories. For coatings comprising zinc and aluminium passivated in depth with chromium oxides the extraction procedure developed herein enabled determination of higher Cr(VI) concentrations. This was also observed for the screw covered with a chromium passivant layer on zinc-nickel. For coating comprising a chromium passivant layer on alkaline zinc the standardized extraction procedure was more efficient

  14. Design Procedure for Hybrid Ventilation

    DEFF Research Database (Denmark)

    Heiselberg, Per; Tjelflaat, Per Olaf

    Mechanical and natural ventilation systems have developed separately during many years. The natural next step in this development is development of ventilation concepts that utilises and combines the best features from each system into a new type of ventilation system - Hybrid Ventilation....... Buildings with hybrid ventilation often include other sustainable technologies and an energy optimisation requires an integrated approach in the design of the building and its mechanical systems. Therefore, the hybrid ventilation design procedure differs from the design procedure for conventional HVAC....... The first ideas on a design procedure for hybrid ventilation is presented and the different types of design methods, that is needed in different phases of the design process, is discussed....

  15. Fusion Imaging for Procedural Guidance.

    Science.gov (United States)

    Wiley, Brandon M; Eleid, Mackram F; Thaden, Jeremy J

    2017-11-27

    The field of percutaneous structural heart interventions has grown tremendously in recent years. This growth has fueled the development of new imaging protocols and technologies in parallel to help facilitate these minimally-invasive procedures. Fusion imaging is an exciting new technology that combines the strength of 2 imaging modalities and has the potential to improve procedural planning and the safety of many commonly performed transcatheter procedures. In this review we discuss the basic concepts of fusion imaging along with the relative strengths and weaknesses of static vs dynamic fusion imaging modalities. This review will focus primarily on echocardiographic-fluoroscopic fusion imaging and its application in commonly performed transcatheter structural heart procedures. Copyright © 2017 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.

  16. Measles Outbreak among Previously Immunized Adult Healthcare Workers, China, 2015

    Directory of Open Access Journals (Sweden)

    Zhengyi Zhang

    2016-01-01

    Full Text Available Measles is caused by measles virus belonging to genus Morbillivirus of the family Paramyxoviridae. Vaccination has played a critical role in controlling measles infection worldwide. However, in the recent years, outbreaks of measles infection still occur in many developing countries. Here, we report an outbreak of measles among healthcare workers and among the 60 measles infected patients 50 were healthcare workers including doctors, nurses, staff, and medics. Fifty-one patients (85% tested positive for IgM antibodies against the measles virus and 50 patients (83.3% tested positive for measles virus RNA. Surprisingly, 73.3% of the infected individuals had been previously immunized against measles. Since there is no infection division in our hospital, the fever clinics are located in the Emergency Division. In addition, the fever and rash were not recognized as measles symptoms at the beginning of the outbreak. These factors result in delay in isolation and early confirmation of the suspected patients and eventually a measles outbreak in the hospital. Our report highlights the importance of following a two-dose measles vaccine program in people including the healthcare workers. In addition, vigilant attention should be paid to medical staff with clinical fever and rash symptoms to avoid a possible nosocomial transmission of measles infection.

  17. Coronary collateral vessels in patients with previous myocardial infarction

    International Nuclear Information System (INIS)

    Nakatsuka, M.; Matsuda, Y.; Ozaki, M.

    1987-01-01

    To assess the degree of collateral vessels after myocardial infarction, coronary angiograms, left ventriculograms, and exercise thallium-201 myocardial scintigrams of 36 patients with previous myocardial infarction were reviewed. All 36 patients had total occlusion of infarct-related coronary artery and no more than 70% stenosis in other coronary arteries. In 19 of 36 patients with transient reduction of thallium-201 uptake in the infarcted area during exercise (Group A), good collaterals were observed in 10 patients, intermediate collaterals in 7 patients, and poor collaterals in 2 patients. In 17 of 36 patients without transient reduction of thallium-201 uptake in the infarcted area during exercise (Group B), good collaterals were seen in 2 patients, intermediate collaterals in 7 patients, and poor collaterals in 8 patients (p less than 0.025). Left ventricular contractions in the infarcted area were normal or hypokinetic in 10 patients and akinetic or dyskinetic in 9 patients in Group A. In Group B, 1 patient had hypokinetic contraction and 16 patients had akinetic or dyskinetic contraction (p less than 0.005). Thus, patients with transient reduction of thallium-201 uptake in the infarcted area during exercise had well developed collaterals and preserved left ventricular contraction, compared to those in patients without transient reduction of thallium-201 uptake in the infarcted area during exercise. These results suggest that the presence of viable myocardium in the infarcted area might be related to the degree of collateral vessels

  18. Knee Osteoarthritis Is Associated With Previous Meniscus and Anterior Cruciate Ligament Surgery Among Elite College American Football Athletes

    Science.gov (United States)

    Smith, Matthew V.; Nepple, Jeffrey J.; Wright, Rick W.; Matava, Matthew J.; Brophy, Robert H.

    2016-01-01

    Background: Football puts athletes at risk for knee injuries such meniscus and anterior cruciate ligament (ACL) tears, which are associated with the development of osteoarthritis (OA). Previous knee surgery, player position, and body mass index (BMI) may be associated with knee OA. Hypothesis: In elite football players undergoing knee magnetic resonance imaging at the National Football League’s Invitational Combine, the prevalence of knee OA is associated with previous knee surgery and BMI. Study Design: Retrospective cohort. Level of Evidence: Level 4. Methods: A retrospective review was performed of all participants of the National Football League Combine from 2005 to 2009 who underwent magnetic resonance imaging of the knee because of prior knee injury, surgery, or knee-related symptoms or concerning examination findings. Imaging studies were reviewed for evidence of OA. History of previous knee surgery—including ACL reconstruction, meniscal procedures, and articular cartilage surgery—and position were recorded for each athlete. BMI was calculated based on height and weight. Results: There was a higher prevalence of OA in knees with a history of previous knee surgery (23% vs 4.0%, P 30 kg/m2 was also associated with a higher risk of OA (P = 0.007) but player position was not associated with knee OA. Conclusions: Previous knee surgery, particularly ACL reconstruction and partial meniscectomy, and elevated BMI are associated with knee OA in elite football players. Future research should investigate ways to minimize the risk of OA after knee surgery in these athletes. Clinical Relevance: Treatment of knee injuries in football athletes should consider chondroprotection, including meniscal preservation and cartilage repair, when possible. PMID:27940573

  19. Knee Osteoarthritis Is Associated With Previous Meniscus and Anterior Cruciate Ligament Surgery Among Elite College American Football Athletes.

    Science.gov (United States)

    Smith, Matthew V; Nepple, Jeffrey J; Wright, Rick W; Matava, Matthew J; Brophy, Robert H

    Football puts athletes at risk for knee injuries such meniscus and anterior cruciate ligament (ACL) tears, which are associated with the development of osteoarthritis (OA). Previous knee surgery, player position, and body mass index (BMI) may be associated with knee OA. In elite football players undergoing knee magnetic resonance imaging at the National Football League's Invitational Combine, the prevalence of knee OA is associated with previous knee surgery and BMI. Retrospective cohort. Level 4. A retrospective review was performed of all participants of the National Football League Combine from 2005 to 2009 who underwent magnetic resonance imaging of the knee because of prior knee injury, surgery, or knee-related symptoms or concerning examination findings. Imaging studies were reviewed for evidence of OA. History of previous knee surgery-including ACL reconstruction, meniscal procedures, and articular cartilage surgery-and position were recorded for each athlete. BMI was calculated based on height and weight. There was a higher prevalence of OA in knees with a history of previous knee surgery (23% vs 4.0%, P 30 kg/m 2 was also associated with a higher risk of OA ( P = 0.007) but player position was not associated with knee OA. Previous knee surgery, particularly ACL reconstruction and partial meniscectomy, and elevated BMI are associated with knee OA in elite football players. Future research should investigate ways to minimize the risk of OA after knee surgery in these athletes. Treatment of knee injuries in football athletes should consider chondroprotection, including meniscal preservation and cartilage repair, when possible.

  20. Towards the Development of a More Accurate Monitoring Procedure for Invertebrate Populations, in the Presence of an Unknown Spatial Pattern of Population Distribution in the Field

    Directory of Open Access Journals (Sweden)

    Natalia B. Petrovskaya

    2018-02-01

    Full Text Available Studies addressing many ecological problems require accurate evaluation of the total population size. In this paper, we revisit a sampling procedure used for the evaluation of the abundance of an invertebrate population from assessment data collected on a spatial grid of sampling locations. We first discuss how insufficient information about the spatial population density obtained on a coarse sampling grid may affect the accuracy of an evaluation of total population size. Such information deficit in field data can arise because of inadequate spatial resolution of the population distribution (spatially variable population density when coarse grids are used, which is especially true when a strongly heterogeneous spatial population density is sampled. We then argue that the average trap count (the quantity routinely used to quantify abundance, if obtained from a sampling grid that is too coarse, is a random variable because of the uncertainty in sampling spatial data. Finally, we show that a probabilistic approach similar to bootstrapping techniques can be an efficient tool to quantify the uncertainty in the evaluation procedure in the presence of a spatial pattern reflecting a patchy distribution of invertebrates within the sampling grid.

  1. Achieving Procedural Competence during Nephrology Fellowship Training: Current Requirements and Educational Research.

    Science.gov (United States)

    Clark, Edward; Barsuk, Jeffrey H; Karpinski, Jolanta; McQuillan, Rory

    2016-12-07

    Concerns have previously been raised as to whether training programs are ensuring that nephrology fellows achieve competence in the procedural skills required for independent practice. We sought to review the current requirements for procedural training as well as educational research pertaining to achieving competence in the core nephrology procedures of nontunneled (temporary) hemodialysis catheter insertion and percutaneous kidney biopsy. At this time, there is no universal approach to procedural training and assessment during nephrology fellowship. Nonetheless, simulation-based mastery learning programs have been shown to be effective in improving fellows' skills in nontunneled (temporary) hemodialysis catheter insertion and should be provided by all nephrology training programs. For percutaneous kidney biopsy, the development and evaluation of inexpensive simulators are a promising starting point for future study. Current practice with respect to procedural training during nephrology fellowship remains imperfect; however, the ongoing shift toward competency-based evaluation provides opportunities to refocus on improvement. Copyright © 2016 by the American Society of Nephrology.

  2. 2 CFR 1.215 - Relationship to previous issuances.

    Science.gov (United States)

    2010-01-01

    ... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false Relationship to previous issuances. 1.215 Section 1.215 Grants and Agreements ABOUT TITLE 2 OF THE CODE OF FEDERAL REGULATIONS AND SUBTITLE A Introduction toSubtitle A § 1.215 Relationship to previous issuances. Although some of the guidance was...

  3. 2 CFR 230.45 - Relationship to previous issuance.

    Science.gov (United States)

    2010-01-01

    ... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false Relationship to previous issuance. 230.45 Section 230.45 Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET CIRCULARS AND GUIDANCE Reserved COST PRINCIPLES FOR NON-PROFIT ORGANIZATIONS (OMB CIRCULAR A-122) § 230.45 Relationship to previous issuance. (a...

  4. Research Note Effects of previous cultivation on regeneration of ...

    African Journals Online (AJOL)

    Research Note Effects of previous cultivation on regeneration of Julbernadia globiflora and Brachystegia spiciformis in grazing areas of Mupfurudzi ... Plant attributes for Julbernadia globiflora and Brachystegia spiciformis were measured in previously cultivated and uncultivated sites making up rangelands of the scheme.

  5. 49 CFR 173.23 - Previously authorized packaging.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Previously authorized packaging. 173.23 Section... REQUIREMENTS FOR SHIPMENTS AND PACKAGINGS Preparation of Hazardous Materials for Transportation § 173.23 Previously authorized packaging. (a) When the regulations specify a packaging with a specification marking...

  6. 75 FR 76056 - FEDERAL REGISTER CITATION OF PREVIOUS ANNOUNCEMENT:

    Science.gov (United States)

    2010-12-07

    ... SECURITIES AND EXCHANGE COMMISSION Sunshine Act Meeting FEDERAL REGISTER CITATION OF PREVIOUS ANNOUNCEMENT: STATUS: Closed meeting. PLACE: 100 F Street, NE., Washington, DC. DATE AND TIME OF PREVIOUSLY ANNOUNCED MEETING: Thursday, December 9, 2010 at 2 p.m. CHANGE IN THE MEETING: Time change. The closed...

  7. Triple outlet right ventricle: a previously unknown cardiac malformation.

    Science.gov (United States)

    Tingo, Jennifer E; Carroll, Sheila J; Crystal, Matthew A

    2015-03-01

    We present the case of an infant with three distinct outflow tracts from the right ventricle. Three outlets from the heart have been previously named the "Tritruncal Heart". We review the two previously reported cases of tritruncal hearts and describe the anatomy, diagnosis, surgical management, and outcome of our case. Embryologic implications are also discussed.

  8. No discrimination against previous mates in a sexually cannibalistic spider

    Science.gov (United States)

    Fromhage, Lutz; Schneider, Jutta M.

    2005-09-01

    In several animal species, females discriminate against previous mates in subsequent mating decisions, increasing the potential for multiple paternity. In spiders, female choice may take the form of selective sexual cannibalism, which has been shown to bias paternity in favor of particular males. If cannibalistic attacks function to restrict a male's paternity, females may have little interest to remate with males having survived such an attack. We therefore studied the possibility of female discrimination against previous mates in sexually cannibalistic Argiope bruennichi, where females almost always attack their mate at the onset of copulation. We compared mating latency and copulation duration of males having experienced a previous copulation either with the same or with a different female, but found no evidence for discrimination against previous mates. However, males copulated significantly shorter when inserting into a used, compared to a previously unused, genital pore of the female.

  9. The procedural egalitarian solution

    NARCIS (Netherlands)

    Dietzenbacher, Bas; Borm, Peter; Hendrickx, Ruud

    2017-01-01

    In this paper we introduce and analyze the procedural egalitarian solution for transferable utility games. This new concept is based on the result of a coalitional bargaining procedure in which egalitarian considerations play a central role. The procedural egalitarian solution is the first

  10. The Procedural Egalitarian Solution

    NARCIS (Netherlands)

    Dietzenbacher, Bas; Borm, Peter; Hendrickx, Ruud

    2016-01-01

    In this paper we introduce and analyze the procedural egalitarian solution for transferable utility games. This new concept is based on the result of a coalitional bargaining procedure in which egalitarian considerations play a central role. The procedural egalitarian solution is the first

  11. Designing Flightdeck Procedures: Literature Resources

    Science.gov (United States)

    Feldman, Jolene; Barshi, Immanuel; Degani, Asaf; Loukopoulou, Loukia; Mauro, Robert

    2017-01-01

    This technical publication contains the titles, abstracts, summaries, descriptions, and/or annotations of available literature sources on procedure design and development, requirements, and guidance. It is designed to provide users with an easy access to available resources on the topic of procedure design, and with a sense of the contents of these sources. This repository of information is organized into the following publication sources: Research (e.g., journal articles, conference proceedings), Manufacturers' (e.g., operation manuals, newsletters), and Regulatory and/or Government (e.g., advisory circulars, reports). An additional section contains synopses of Accident/Incident Reports involving procedures. This work directly supports a comprehensive memorandum by Barshi, Mauro, Degani, & Loukopoulou (2016) that summarizes the results of a multi-year project, partially funded by the FAA, to develop technical reference materials that support guidance on the process of developing cockpit procedures (see "Designing Flightdeck Procedures" https://ntrs.nasa.gov/archive/nasa/casi.ntrs.nasa.gov/20160013263.pdf). An extensive treatment of this topic is presented in a forthcoming book by the same authors.

  12. Writer`s guide for technical procedures

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-01

    A primary objective of operations conducted in the US Department of Energy (DOE) complex is safety. Procedures are a critical element of maintaining a safety envelope to ensure safe facility operation. This DOE Writer`s Guide for Technical Procedures addresses the content, format, and style of technical procedures that prescribe production, operation of equipment and facilities, and maintenance activities. The DOE Writer`s Guide for Management Control Procedures and DOE Writer`s Guide for Emergency and Alarm Response Procedures are being developed to assist writers in developing nontechnical procedures. DOE is providing this guide to assist writers across the DOE complex in producing accurate, complete, and usable procedures that promote safe and efficient operations that comply with DOE orders, including DOE Order 5480.19, Conduct of Operations for DOE Facilities, and 5480.6, Safety of Department of Energy-Owned Nuclear Reactors.

  13. Adolescents previously involved in Satanism experiencing mental health problems

    Directory of Open Access Journals (Sweden)

    H Heathcote

    1999-09-01

    Full Text Available No research has previously been done regarding the phenomenon of adolescents who have previously been involved in Satanism and who experience obstacles in their strive for mental health. Adolescents previously involved in Satanism present behavioral problems like aggressive outbursts, depression, “ psychosis” or suicide attempts, that could lead to suicide. In the phenomenonanalysis semi-structured, phenomenological interviews were performed with the respondents and their parents. The respondents were requested to write a naïve sketch about their life. After completion of the data-control, guidelines for nursing staff were set.

  14. Rupture of a previously scarred uterus during second trimester ...

    African Journals Online (AJOL)

    Misoprostol is useful in ripening the cervix prior to mid-trimester termination of pregnancy. It is particularly indicated in cases of missed abortions whether the uterus is scarred or not. The procedure is safe in the majority of cases. We present a case of uterine rupture during induction of labour with vaginal misoprostol for a ...

  15. Development of a simple proton nuclear magnetic resonance-based procedure to estimate the approximate distribution coefficient at physiological pH (logD7.4)

    DEFF Research Database (Denmark)

    Stéen, E Johanna L; Nyberg, Nils; Lehel, Szabolcs

    2017-01-01

    D7.4) in 1-octanol and D2O buffer. The method can be applied to both UV and non-UV active compounds. In addition, neither calibration curves nor internal/external standards are needed. We have demonstrated that logD7.4 can be accurately measured using 1H NMR for compounds within the logD7.4 interval...... between 0.7 and 3.3. The method was also compared to a previously described HPLC method....

  16. Automated emergency operating procedures

    International Nuclear Information System (INIS)

    Perez-Ramirez, G.; Nelson, P.F.

    1990-01-01

    This paper describes the development of a training tool for the symptom oriented emergency operating procedures used at the Laguna Verde Nuclear Power Plant. EOPs and operator training are intended to assist the operator for managing accident situations. A prototype expert system based on the EOPs has been developed for operator training. The demonstration expert system was developed using a commercial shell. The knowledge base consists of two parts. The specific operator actions to be executed for 5 selected accident sequences and the EOPs steps for the reactor pressure vessel control of the water level, pressure, and power. The knowledge is expressed in the form of IF-THEN production rules. A typical training session will display a set of conditions and will prompt the trainee to indicate the appropriate step to perform. This mode will guide the trainee through selected accident sequences. A second mode of the expert system will prompt the trainee for the current plant conditions and the expert system will respond with the EOPs which are required to be performed under these conditions. This allows the trainee to study What if situations

  17. Procedure to determine the optimal main primary coolant pump parameters of the FRG-1 reactor. P.1: Development concept, optimization criteria and general logical structure of the procedure; Verfahren zur Bestimmung der optimalen Kenndaten der Hauptprimaerumwaelzpumpe nach der Kernkompaktierung des Reaktors FRG-1. T.1: Entwicklungskonzept, Optimierungskriterien und allgemeine logische Struktur des Verfahrens

    Energy Technology Data Exchange (ETDEWEB)

    Pihowicz, W. [GKSS-Forschungszentrum Geesthacht GmbH (Germany). Zentralabteilung Forschungsreaktoren

    1998-12-31

    First a development concept of the procedure was derived. Following this concept the procedure has to be derived stepwise, i.e. on subsequent logical levels. Furthermore, the report contains the results of the first two logical levels. On the first (basic) level the optimization criteria had been formulated. The general logical structure of the procedure results from the second logical level (macro level) of the evaluation process. This structure consists of four determination blocks, one identification unit and some determination elements as well as their logical interconnections in the form of decision and result units. The blocks serve for the realization of the closed and composed partial tasks of the procedure. They themselves form the complicated but not yet deviced partial structures, which again are the logical connections of the determination elements. In contrast to the blocks all determination elements are simple enough, so that their direct mathematical determination becomes possible. They serve for the solution of simple partial tasks. (orig.) [Deutsch] Zuerst wurde ein Konzept zur Entwicklung des Verfahrens erstellt. Nach dem Konzept soll das Verfahren stufenweise, auf nacheinander folgenden logischen Ebenen abgeleitet werden. Ausserdem enthaelt die Abhandlung noch die auf den zwei anfaenglichen logischen Ebenen des Entwicklungsprozesses erzielten Resultate. Auf der ersten Ebene (Grundebene) wurden die Optimierungskriterien formuliert. Die allgemeine logische Struktur des Verfahrens ergibt sich als Resultat der zweiten logischen Ebene (Makroebene) des Entwicklungsprozesses. Diese Struktur setzt sich aus vier Bestimmungsbloecken, einer Identifikationseinheit und einigen Bestimmungselementen sowie ihrer logischen Verknuepfung in Form der Entscheidungs- und Ergebniseinheiten zusammen. Die Bloecke dienen zur Realisierung der geschlossenen und zusammengesetzten Teilaufgaben des Verfahrens. Sie bilden selbst die komplizierten, jedoch noch nicht abgeleiteten

  18. Influence of previous participation in physical activity on its ...

    African Journals Online (AJOL)

    ... participation can influence perceptions of PA among the students. Physical activity promotion programmes should consider the role of these factors which should be emphasised from childhood. Keywords: physical activity, students, perceived benefits, perceived barriers, previous participation, sedentary lifestyle, Rwanda

  19. Choice of contraception after previous operative delivery at a family ...

    African Journals Online (AJOL)

    Choice of contraception after previous operative delivery at a family planning clinic in Northern Nigeria. Amina Mohammed‑Durosinlorun, Joel Adze, Stephen Bature, Caleb Mohammed, Matthew Taingson, Amina Abubakar, Austin Ojabo, Lydia Airede ...

  20. Payload specialist Reinhard Furrer show evidence of previous blood sampling

    Science.gov (United States)

    1985-01-01

    Payload specialist Reinhard Furrer shows evidence of previous blood sampling while Wubbo J. Ockels, Dutch payload specialist (only partially visible), extends his right arm after a sample has been taken. Both men show bruises on their arms.